-- dump date   	20140618_205853
-- class       	Genbank::Feature
-- table       	feature
-- table       	main
-- field 1	id
-- field 2	type
-- field 3	name
-- field 4	contig
-- field 5	start_pos
-- field 6	end_pos
-- field 7	strand
-- field 8	description
-- field 9	chrom_position
-- field 10	organism
-- field 11	GeneID
-- header
-- id	type	name	contig	start_pos	end_pos	strand	description	chrom_position	organism	GeneID
62928000001	SEQ_END	SEQ_END	NC_008702.1	4376040	4376040	DR	NC_008702.1; contig end	4376040..4376040	Azoarcus sp. BH72	<NULL_VALUE>
YP_931506.1	CDS	dnaA	NC_008702.1	1	1443	D	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein	1..1443	Azoarcus sp. BH72	4610202
YP_931507.1	CDS	dnaN	NC_008702.1	1502	2611	D	DNA polymerase III beta chain (EC 2.7.7.7). DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA It slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity). InterPro: DNA polymerase III beta chain dnan: DNA polymerase III beta subunit; High confidence in function and specificity; DNA-directed DNA polymerase	1502..2611	Azoarcus sp. BH72	4608630
YP_931508.1	CDS	gyrB	NC_008702.1	2821	5310	D	negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B	2821..5310	Azoarcus sp. BH72	4608638
YP_931509.1	CDS	hsdM	NC_008702.1	5505	7346	D	METHYLATION OF SPECIFIC ADENINE RESIDUES; REQUIRED FOR BOTH RESTRICTION AND MODIFICATION ACTIVITIES (BY SIMILARITY), TREMBL:Q7VCN2 (55% identity). InterPro (IPR002296): N6 adenine-specific DNA methyltransferase,N12 class. InterPro (IPR003356): N-6 DNA methylase. InterPro (IPR003665): Type I restriction-modification system M subunit. Pfam (PF02384): N-6 DNA Methylase. Pfam (PF02506): Type I restriction modification system, M protein.; High confidence in function and specificity; site-specific DNA-methyltransferase	5505..7346	Azoarcus sp. BH72	4608976
YP_931510.1	CDS	mloB	NC_008702.1	7453	8910	D	Putative restriction modification gene,; Function unclear; putative restriction modification gene	7453..8910	Azoarcus sp. BH72	4609031
YP_931511.1	CDS	azo0006	NC_008702.1	8919	9038	D	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank no domains predicted no signal peptide no TMHS; hypothetical protein	8919..9038	Azoarcus sp. BH72	4609226
YP_931512.1	CDS	hsdS	NC_008702.1	9035	10384	D	S subunit, DNA SPECIFICITY SUBUNIT REQUIRED FOR RESTRICTION AND MODIFICATION, TREMBL:Q9AAH7 (31% identity); TREMBL:Q8PIJ8 (28% identity). Pfam (PF01420): Type I restriction modification DNA specificity domain. InterPro (IPR000055): Restriction modification system DNA specificity domain.; High confidence in function and specificity; Type I site-specific deoxyribonuclease	9035..10384	Azoarcus sp. BH72	4606149
YP_931513.1	CDS	azo0008	NC_008702.1	10381	11256	D	Conserved hypothetical protein. Homology to RB11641 of R.baltica of 42% (tremble:Q7TTG8). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	10381..11256	Azoarcus sp. BH72	4609033
YP_931514.1	CDS	azo0009	NC_008702.1	11468	11794	D	Transcriptional regulatory protein, 35% identity to TrEMBL;Q89JK0. Has Prosite, PS01117; HTH_MARR_1 domain; The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH)domain of about 135 amino acids present in transcription regulators of the marR/slyA family,involved in the development of antibiotic resistance; Function unclear; transcriptional regulator	11468..11794	Azoarcus sp. BH72	4606150
YP_931515.1	CDS	hsdR	NC_008702.1	11948	15061	D	SUBUNIT R IS REQUIRED FOR BOTH NUCLEASE AND ATPASE ACTIVITIES BUT NOT FOR MODIFICATION (BY SIMILARITY),TREMBL:Q9AAH5 (64% identity); TREMBL:Q8FUH0 (40% identity). InterPro (IPR001410): DEAD/DEAH box helicase TIGRFAM (TIGR00348): Type I site-specific deoxyribonuclease, HsdR family.; High confidence in function and specificity; Type I site-specific deoxyribonuclease	11948..15061	Azoarcus sp. BH72	4606151
YP_931516.1	CDS	azo0011	NC_008702.1	15231	16085	R	The short-chain dehydrogenases/reductases family is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases, similarity to SWISSPROT:P37959 (35% identity); TREMBL:Q930L8 (44% identity); TREMBL:Q9I3W5 (41% identity). Pfam (PF00106): Short chain dehydrogenase. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase.; Specificity unclear; short-chain dehydrogenase	complement(15231..16085)	Azoarcus sp. BH72	4609032
YP_931517.1	CDS	bdhR	NC_008702.1	16203	17150	D	Transcriptional regulator, LysR family,; High confidence in function and specificity; LysR family transcriptional regulator	16203..17150	Azoarcus sp. BH72	4606152
YP_931518.1	CDS	rluA1	NC_008702.1	17232	17876	D	Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs .; Family membership; pseudouridine synthase A	17232..17876	Azoarcus sp. BH72	4608384
YP_931519.1	CDS	nifF1	NC_008702.1	18010	18567	R	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA	complement(18010..18567)	Azoarcus sp. BH72	4609731
YP_931520.1	CDS	azo0015	NC_008702.1	18971	19501	R	Conserved hypothetical protein, 50% identitcal(67% similarity) to TrEMBL;Q888U7.TrEMBL;Q747X0(33% identity). Has PF03473, MOSC domain;IPR005302; The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms such as P32157, or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine,and delivers it for the formation of diverse sulfur-metal clusters.; Function unclear; hypothetical protein	complement(18971..19501)	Azoarcus sp. BH72	4609361
YP_931521.1	CDS	azo0016	NC_008702.1	19505	19855	R	Conserved hypothetical membrane protein. Homology to Daro03002995 of Dechloromonas aromatica of 34% (ZP_00348572.1). No signal peptide present. TMHMM reporting one transmembrane helix. No domains predicted.; Conserved hypothetical protein; hypothetical protein	complement(19505..19855)	Azoarcus sp. BH72	4606153
YP_931522.1	CDS	azo0017	NC_008702.1	19882	20355	R	Hypothetical protein, 28% identity to TrEMBL;Q8E8U4. Has PF07049, Protein of unknown function (DUF1332); IPR010755;This family consists of several hypothetical bacterial proteins of around 165 residues in length. The function of this family is unknown.; Function unclear; hypothetical protein	complement(19882..20355)	Azoarcus sp. BH72	4606154
YP_931523.1	CDS	azo0018	NC_008702.1	20480	21061	R	InterPro (IPR002818): ThiJ/PfpI. Pfam (PF01965): DJ-1/PfpI family.; Specificity unclear; ThiJ/PfpI family protein	complement(20480..21061)	Azoarcus sp. BH72	4606155
YP_931524.1	CDS	azo0019	NC_008702.1	21263	22402	D	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to trembl|Q8XVG7 (38%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Function unclear; extracellular ligand binding protein	21263..22402	Azoarcus sp. BH72	4606156
YP_931525.1	CDS	azo0020	NC_008702.1	22404	23309	R	Probable transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	complement(22404..23309)	Azoarcus sp. BH72	4606157
YP_931526.1	CDS	iorA	NC_008702.1	23470	23928	D	Probable isoquinoline 1-oxidoreductase, alpha subunit Homology to iroA of B. diminuta of 58% (sprot|IORA_BREDI). InterPro: [2Fe-2S] binding domain (IPR002888); Ferredoxin (IPR001041) Pfam: 2FE-2S iron-sulfur cluster binding domein, [2Fe-2S] binding domain no signal peptide no TMHs; Specificity unclear; isoquinoline 1-oxidoreductase subunit alpha	23470..23928	Azoarcus sp. BH72	4606158
YP_931527.1	CDS	iorB	NC_008702.1	23939	26152	D	Putative isoquinoline 1-oxidoreductase, beta subunit Homology to iorB of B. diminuta of 34% (sprot|IORB_BREDI). InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus (IPR000674) Pfam: Aldehyde oxidase and xanthine dehydrogenase signal peptide no TMHs; Family membership; putative isoquinoline 1-oxidoreductase subunit beta	23939..26152	Azoarcus sp. BH72	4609085
YP_931528.1	CDS	azo0023	NC_008702.1	26175	27197	D	Conserved hypothetical protein (Xanthine like-dehydrogenase accessory factor). Homology to Rsc1464 (hyp. protein) of R. solanacearum of 66% (CAD15165). InterPro: DUF182 Pfam: uncharacterized BCR, COG1975 no signal peptide no TMHs; hypothetical protein	26175..27197	Azoarcus sp. BH72	4609086
YP_931529.1	CDS	azo0024	NC_008702.1	27194	27763	D	Purine catabolism protein pucB. TREMBL:Q8XZ0: 40% identity, 47% similarity Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase. FUNCTION: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) (By similarity). PATHWAY: Molybdenum cofactor biosynthesis. SUBCELLULAR LOCATION: Cytoplasmic (By similarity). SIMILARITY: Belongs to the mobA family. Pfam:UPF0007:Uncharacterized protein family UPF000 ispD: 4-diphosphocytidyl-2C-methyl-D-er Non-secretory protein with signal peptide probability: 0 No TMH's (TMHMM predicted).; Function unclear; hypothetical protein	27194..27763	Azoarcus sp. BH72	4606159
YP_931530.1	CDS	azo0025	NC_008702.1	28052	28618	D	Hypothetical protein yddH. TREMBL:Q7NTI1:66% identity, 76% similarity InterPro:IPR002563; Flavin_Reduct. Pfam:PF01613; Flavin_Reduct; InterPro: Flavin reductase-like domain Non-secretory protein with no signal peptide. No transmembrane helices TIGR00357: PilB-related protein; High confidence in function and specificity; hypothetical protein	28052..28618	Azoarcus sp. BH72	4606160
YP_931531.1	CDS	acbB	NC_008702.1	28631	29569	R	dTDP-glucose 4,6-dehydratase, AcbB,probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. 30% dTDP_gluc_dehyt.IPR001509; Epimerase_Dh. Pfam:PF01370; Epimerase; 1. TIGRFAMs:TIGR01181; dTDP_gluc_dehyt; 1.; High confidence in function and specificity; putative dTDP-glucose 4-6-dehydratase	complement(28631..29569)	Azoarcus sp. BH72	4606161
YP_931532.1	CDS	exoU	NC_008702.1	29590	30477	D	Putative glycosyl transferase. Weak Homology with hits spanning the entire length of protein. 24% identitcal to TrEMBL;Q8F209.TrEMBL; Q89D69(33% identity) Has PF00535,Glycosyl transferase:IPR001173;Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. The biosynthesis of disaccharides,oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These are enzymes that catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules,forming glycosidic bonds.; Family membership; glycosyltransferase	29590..30477	Azoarcus sp. BH72	4608253
YP_931533.1	CDS	azo0028	NC_008702.1	30502	30732	R	Conserved hypothetical membrane protein Homology to cv0580 of C. violaceum of 41% (trembl|Q7P0I7(SRS)) no domains predicted no signal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(30502..30732)	Azoarcus sp. BH72	4608706
YP_931534.1	CDS	azo0029	NC_008702.1	30906	31676	D	Similar to a tellurium resistance protein TerC. Belongs to the terC family. This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. Similar to a putative membrane protein TerC,80% identity to TrEMBL; Q5P410 from Azoarcus sp EnN1. 50% RNA_rec_mot.IPR005496; TerC. Pfam:PF03741; TerC; 1. TIGR:SPTO2691. TMHelix:5.; Conserved hypothetical protein; hypothetical protein	30906..31676	Azoarcus sp. BH72	4606162
YP_931535.1	CDS	gltR	NC_008702.1	31735	32625	R	HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; LysR family transcriptional regulator	complement(31735..32625)	Azoarcus sp. BH72	4606163
YP_931536.1	CDS	azo0031	NC_008702.1	32784	34019	D	Permease member of the Major Facilitator Superfamily (MFS).MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 25% MFS.IPR005828; Sub_transporter. Pfam:PF00083; sugar_tr; 1. TMHelix: 10.; High confidence in function and specificity; putative MFS transporter permease	32784..34019	Azoarcus sp. BH72	4608917
YP_931537.1	CDS	azo0032	NC_008702.1	34326	34814	R	Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 31% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(34326..34814)	Azoarcus sp. BH72	4606164
YP_931538.1	CDS	azo0033	NC_008702.1	35113	35601	D	Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 42% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	35113..35601	Azoarcus sp. BH72	4606165
YP_931539.1	CDS	azo0034	NC_008702.1	35640	37502	D	Conserved hypothetical secreted protein. Homology to PP2042 of P. putida of 34% (TrEMBL;Q88L93) Has PF06980:(IPR010727)Protein of unknown function (DUF1302);This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. No TMHs signal peptide present.; Conserved hypothetical protein; hypothetical protein	35640..37502	Azoarcus sp. BH72	4606166
YP_931540.1	CDS	azo0035	NC_008702.1	37514	38869	D	Conserved hypothetical secreted protein. Homology to PA3421 of P. aeruginosa of 50% (TrEMBL;Q9HYI4) Has (IPR010752)PF07044:Protein of unknown function (DUF1329);This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs signal peptide present; Conserved hypothetical protein; hypothetical protein	37514..38869	Azoarcus sp. BH72	4606167
YP_931541.1	CDS	azo0036	NC_008702.1	38945	40102	D	Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 40% (trembl|Q88I01). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide no TMHs; Function unclear; hypothetical protein	38945..40102	Azoarcus sp. BH72	4606168
YP_931542.1	CDS	azo0037	NC_008702.1	40095	42521	D	Putative membrane protein MJ1562. TREMBL:Q88LB6: 47% identity, 63% similarity InterPro:IPR000731; SSD_5TM InterPro: HMGCR/Patched 5TM box Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide absent. Presence of 12 transmembrane helices; Family membership; RND efflux transporter	40095..42521	Azoarcus sp. BH72	4606169
YP_931543.1	CDS	azo0038	NC_008702.1	42527	43336	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. EntA,a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase enzyme,is involved in the third stage of enterobactin biosynthesis and converts isochorismate to 2,3-dihydroxybenzoic acid (DHBA), SWISSPROT:Q10855 (37% identity); TREMBL:Q89M15 (36% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. InterPro (IPR003560): 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	42527..43336	Azoarcus sp. BH72	4606170
YP_931544.1	CDS	azo0039	NC_008702.1	43466	45670	D	Conservd hypothetical protein, 79% identity(85% similarity) to TrEMBL;Q88GU7. Has PF02566, OsmC-like protein; IPR003718; Osmotically inducible protein C (OsmC) (P23929) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein (O68390) that has a novel pattern of oxidative stress regulation. Has PF02624, YcaO-like fatty acid binding protein;IPR003776, DUF181;This is a family of proteins of unknown function.; hypothetical protein	43466..45670	Azoarcus sp. BH72	4606171
YP_931545.1	CDS	azo0040	NC_008702.1	45701	46612	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(45701..46612)	Azoarcus sp. BH72	4606172
YP_931546.1	CDS	azo0041	NC_008702.1	46800	47561	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q9I376 (49% identity); SWISSPROT:P50197 (44% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	46800..47561	Azoarcus sp. BH72	4606173
YP_931547.1	CDS	azo0042	NC_008702.1	47901	48494	D	Conserved hypothetical secreted protein. Homology to bll2189 of B. japonicum of 48% (trembl|Q89T61). Has PF06577, Protein of unknown function (DUF1134);IPR008325,UCP033924; This family consists of several hypothetical bacterial proteins of unknown function. Signal peptide. TMH present in signal peptide.; Conserved hypothetical protein; hypothetical protein	47901..48494	Azoarcus sp. BH72	4606174
YP_931548.1	CDS	azo0043	NC_008702.1	48804	49574	R	Hypothetical UPF0271 protein PYRAB09930. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes,lamA and lamB, involved in the utilization of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression [1]. The exact molecular function of the proteins in this family is unknown. SPROT:Q89LH6: 47% identity, 62% similarity InterPro:IPR005501; LamB_YcsF. Pfam:PF03746; LamB_YcsF urease_gam: urease gamma subunit Nonsecretory protein with Signal peptide probability 0 No transmembrane helices; Family membership; hypothetical protein	complement(48804..49574)	Azoarcus sp. BH72	4606175
YP_931549.1	CDS	azo0044	NC_008702.1	49571	50671	R	Conserved hypothetical urea amidolyase-related protein. Homology to ybgK of E. coli of 36% (sprot|YBGK_ECOLI). InterPro: DUF183 (IPR003778) Uncharacterized domain in proteins of unknown function. This domain is found in a multifunctional enzyme, urea amidolyase, from yeast. Pfam: DFU182, uncharcterized ACR,COG1984 no signal peptide no TMHs; Function unclear; hypothetical protein	complement(49571..50671)	Azoarcus sp. BH72	4606176
YP_931550.1	CDS	azo0045	NC_008702.1	50668	51462	R	Conserved hypothetical protein ybgJ. Homology to ybgJ of E. coli of 41% (sprot|YBGJ_ECOLI) InterPro: DUF213 (IPR003833) Pfam: DUF213, uncharacterized ACR, COG2049 no signal peptide no TMHs; Function unclear; hypothetical protein	complement(50668..51462)	Azoarcus sp. BH72	4606177
YP_931551.1	CDS	dehH	NC_008702.1	51590	52516	R	Hypothetical haloacetate dehalogenase H-1 (EC 3.8.1.3). Haloacetate + H(2)O = glycolate + halide TREMBL:Q8Y2S9: 58% identity, 67% similarity Gene name:dehH from Ralstonia solanacearum genome project. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1 nadp_idh_euk: isocitrate dehydrogenase No TMH present absence of signal peptide.; Family membership; haloacetate dehalogenase	complement(51590..52516)	Azoarcus sp. BH72	4606178
YP_931552.1	CDS	azo0047	NC_008702.1	52582	53337	R	Conserved hypothetical secreted protein Homology to pa4487 of P. aeruginosa of 52% (trembl|Q9HVT4(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(52582..53337)	Azoarcus sp. BH72	4608618
YP_931553.1	CDS	azo0048	NC_008702.1	53315	54151	R	Conserved hypothetical secreted protein. Homology to rsc3028 of R. solanacearum of 57% (trembl|Q8XV04(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(53315..54151)	Azoarcus sp. BH72	4606179
YP_931554.1	CDS	azo0049	NC_008702.1	54285	56000	R	Conserved hypothetical secreted protein. Homology to PA4488 of P. aeruginosa of 47% (trembl|Q9HVT3(SRS)) No domains predicted. No TMHs. Singal Peptide Present.; Conserved hypothetical protein; hypothetical protein	complement(54285..56000)	Azoarcus sp. BH72	4606180
YP_931555.1	CDS	phaZ	NC_008702.1	56050	57162	R	This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate,TREMBL:Q9LBN6 (35% identity); TREMBL:Q46334 (34% identity). SignalP predicting signal peptide.; High confidence in function and specificity; Poly (3-hydroxybutyrate) depolymerase	complement(56050..57162)	Azoarcus sp. BH72	4606181
YP_931556.1	CDS	azo0051	NC_008702.1	57268	58020	R	Conserved hypothetical membrane protein. Homology to ebA624 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA624(KEGG)) . no domains predicted. no signal peptide. 3 TMHs; hypothetical protein	complement(57268..58020)	Azoarcus sp. BH72	4609538
YP_931557.1	CDS	azo0052	NC_008702.1	58066	59952	D	Hypothetical secreted protein. No homology of the entire protein to the data bank. InterPro:Esterase/lipase/thioesterase family active site Pfam:Putative serine esterase (DUF676) This family of proteins are probably serine esterase type enzymes. Signal peptide present (Signal P predicted) No transmembrane helices.; hypothetical protein	58066..59952	Azoarcus sp. BH72	4606182
YP_931558.1	CDS	rstB	NC_008702.1	59974	61287	R	Probable two component sensor histidine kinase,; Specificity unclear; sensor histidine kinase	complement(59974..61287)	Azoarcus sp. BH72	4606183
YP_931559.1	CDS	rstA	NC_008702.1	61284	62054	R	Two component response regulator,; Specificity unclear; two-component response regulator	complement(61284..62054)	Azoarcus sp. BH72	4609829
YP_931560.1	CDS	azo0055	NC_008702.1	62241	62975	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O54136 (41% identity); TREMBL:Q8RCZ7 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; ABC transporter ATP-binding protein	62241..62975	Azoarcus sp. BH72	4609828
YP_931561.1	CDS	azo0056	NC_008702.1	62972	64369	D	Conserved hypothetical membrane protein. Homology to cv3942 of C. violaceum of 30% (trembl|Q7NR42) InterPro: DUF214 (IPR003838) Pfam: Predicted permease This is a family of predicted permeases and hypothetical transmembrane proteins. One member has been shown to transport lipids targeted to the outer membrane across the inner membrane, a step which requires ATP. Signal peptide 3 TMHs; Conserved hypothetical protein; hypothetical protein	62972..64369	Azoarcus sp. BH72	4606184
YP_931562.1	CDS	azo0057	NC_008702.1	64362	65171	D	Conserved hypothetical secreted protein. Homology to BPSS2323 of Burkholderia pseudomallei of 45% (trembl:Q63HU7). no domains predicted. singal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	64362..65171	Azoarcus sp. BH72	4606185
YP_931563.1	CDS	azo0058	NC_008702.1	65168	66349	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide TMHs inside of the signal peptide.; hypothetical protein	65168..66349	Azoarcus sp. BH72	4606186
YP_931564.1	CDS	azo0059	NC_008702.1	66440	71053	R	Conserved hypothetical secreted protein. Homology to rsc3030 of R. solanacearum of 48% (sprot|YU30_RALSO) Pfam: Alpha-2-macroglobulin family Nterminal region (PF01835, PF07703) signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(66440..71053)	Azoarcus sp. BH72	4606187
YP_931565.1	CDS	azo0060	NC_008702.1	71064	71747	R	Conserved hypothetical secreted protein. Homology to RS04726 of R. solanacearum of 55% (trembl|Q8XV01(SRS)) Has PF06672;(IPR009558)Protein of unknown function (DUF1175):This family consists of several hypothetical bacterial proteins of around 210 residues in length. The function of this family is unknown. No TMHs signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(71064..71747)	Azoarcus sp. BH72	4606188
YP_931566.1	CDS	azo0061	NC_008702.1	71744	73438	R	Conserved hypothetical secreted protein. Homology to RS04725 of Ralstonia solanacearum of 43% (trembl|Q8XV00(SRS)) No domains predicted. Signal Peptide Present. NO TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(71744..73438)	Azoarcus sp. BH72	4606189
YP_931567.1	CDS	azo0062	NC_008702.1	73627	75072	D	Conserved hypothetical protein. Homology to MCA0287 of Methylococcus capsulatus of 48% (trembl:Q60C24). no domains predicted. no signal peptide. no TMHs; hypothetical protein	73627..75072	Azoarcus sp. BH72	4606190
YP_931568.1	CDS	azo0063	NC_008702.1	75089	75535	D	Hypothetical protein. No good homology to the data bank. No domains predicted. No TMHs Probable signal peptide.; hypothetical protein	75089..75535	Azoarcus sp. BH72	4606191
YP_931569.1	CDS	azo0064	NC_008702.1	75546	76649	R	Hypothetical protein ydiK.Integral membrane protein (potential). similarity:belongs to the upf0118 (perm) family TREMBL:Q7WQ94: 68% identity; 81% similarity. PIR:AD2790; AD2790.C97569; C97569. InterPro:IPR000585; Hemopexin. IPR002549; UPF0118. Pfam: PF01594; UPF0118; 2A0604s01: protein-export membrane pro Pfam: presence of DUF20 domain and branched chain amino acid transport. TIGRFAM: general nitrate transport. Signal P predicted signal peptide and TMHMM predicted transmembrane helices.; Function unclear; permease	complement(75546..76649)	Azoarcus sp. BH72	4606192
YP_931570.1	CDS	azo0065	NC_008702.1	76751	77287	R	64% similarity with ABC-type multidrug transport system, ATPase and permease components [Dechloromonas aromatica RCB]. and; hypothetical protein	complement(76751..77287)	Azoarcus sp. BH72	4606193
YP_931571.1	CDS	azo0066	NC_008702.1	77284	78402	R	Enoyl-CoA hydratase and 3-2trans-enoyl-CoA isomerase are two enzymes involved in fatty acid metabolism. ECH catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA and ECI shifts the 3- double bond of the intermediates of unsaturated fatty acid oxidation to the 2-trans position.In Escherichia coli (gene fadB) and Pseudomonas fragi (gene faoA), ECH and ECI are also part of a multifunctional enzyme which contains both a HCDH and a 3-hydroxybutyryl-CoA epimerase domain. InterPro: Enoyl-CoA hydratase/isomerase Entry name TREMBL:Q8PMW0 Prim. accession # Q8PMW0 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1 Identities = 169/379 (44%) Number of predicted TMHs: 0 Signal peptide probability: 0.000; Family membership; enoyl-CoA hydratase/isomerase	complement(77284..78402)	Azoarcus sp. BH72	4606194
YP_931572.1	CDS	polC	NC_008702.1	78461	79156	D	DNA polymerase III polC-type (EC 2.7.7.7) (PolIII). Required for replicative DNA synthesis. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). InterPro: Exonuclease dnaq: DNA polymerase III epsilon subun; High confidence in function and specificity; DNA-directed DNA polymerase	78461..79156	Azoarcus sp. BH72	4606195
YP_931573.1	CDS	azo0068	NC_008702.1	79164	79916	R	Hypothetical protein. No good homology with any hits of this length protein. No Domains/Features/motifs/signal peptide present.; hypothetical protein	complement(79164..79916)	Azoarcus sp. BH72	4609597
YP_931574.1	CDS	azo0069	NC_008702.1	80013	80393	D	Conserved hypothetical globin-like protein. Homology to rpa2719 of R. palustris of 46% (tremblnew|CAE28161). Interpro: IPR009050 Globin-like. Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. No signal peptide. No TMHs; Function unclear; globin-like protein	80013..80393	Azoarcus sp. BH72	4606196
YP_931575.1	CDS	azo0070	NC_008702.1	80397	80645	R	Hypothetical membrane protein. no homology to the data bank. no domains predicted.signal peptide. 1 TMHs; hypothetical protein	complement(80397..80645)	Azoarcus sp. BH72	4606197
YP_931576.1	CDS	azo0071	NC_008702.1	80784	82139	D	Sigma-54 dependent response regulator,; Specificity unclear; sigma-54 dependent response regulator	80784..82139	Azoarcus sp. BH72	4606198
YP_931577.1	CDS	azo0072	NC_008702.1	82158	84344	D	Putative two component sensor histidine kinase,; Specificity unclear; putative sensor histidine kinase	82158..84344	Azoarcus sp. BH72	4606199
YP_931578.1	CDS	azo0073	NC_008702.1	84372	85583	D	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Probable sugar-proton symporter transmembrane protein ProP proline/betaine transporter. Low homology to the hypothetical protein ycxA (ORF5)involved in the biosynthesis of the pepitde antibiotic Bacitracin in B. subtilis. Signal peptide; Specificity unclear; putative MFS permease	84372..85583	Azoarcus sp. BH72	4606200
YP_931579.1	CDS	azo0074	NC_008702.1	85691	87382	D	Hypothetical protein yfbK. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders [1]. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. trembl:Q8P6Q2: 55% identity; 66% similarity InterPro:IPR002016; Peroxidase. IPR002035; VWF_A. Pfam: PF00092; VWA; 1. SMART: SM00327; VWA; 1. cdhD: CO dehydrogenase/acetyl-CoA syn Signal peptide present (0.927 probability); SignalP predicted. No transmembrane helices (TMHMM predicted).; Function unclear; hypothetical protein	85691..87382	Azoarcus sp. BH72	4606201
YP_931580.1	CDS	rpoE	NC_008702.1	87379	87978	D	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor	87379..87978	Azoarcus sp. BH72	4606202
YP_931581.1	CDS	azo0076	NC_008702.1	87975	88751	D	Conserved hypothetical membrane protein. Homology to BB3269 of Bordetella bronchiseptica of 31% (trembl|Q7WHD9(SRS)). No domains predicted. no signal peptide 1 TMH; Conserved hypothetical protein; hypothetical protein	87975..88751	Azoarcus sp. BH72	4609798
YP_931582.1	CDS	azo0077	NC_008702.1	88772	88993	R	Hypothetical protein. No Good homologs. No Domains/Features/Motifs reported present.; hypothetical protein	complement(88772..88993)	Azoarcus sp. BH72	4606203
YP_931583.1	CDS	azo0078	NC_008702.1	89004	89966	R	Hypothetical protein. Weak homology with hits over entire length. PS50821; PAZ domain present(Prosite); hypothetical protein	complement(89004..89966)	Azoarcus sp. BH72	4606204
YP_931584.1	CDS	rtcB	NC_008702.1	90144	91352	R	rtcB protein, 57% identical(70% similairty) to TrEMBL;Q7NZ85 TrEMBL;Q8FCS7(56% identity). Has IPR001233;UPF0027(PF01139, Uncharacterized protein family):A number of uncharacterized proteins including Escherichia coli rtcB, Mycobacterium tuberculosis MtCY441.01., Caenorhabditis elegans F16A11.2 and Methanococcus jannaschii MJ0682 belong to this family. Has no Signal peptide or TMH present.; High confidence in function and specificity; rtcB protein	complement(90144..91352)	Azoarcus sp. BH72	4606205
YP_931585.1	CDS	prfC	NC_008702.1	91812	93434	D	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3	91812..93434	Azoarcus sp. BH72	4609831
YP_931586.1	CDS	azo0081	NC_008702.1	93454	93981	D	Conserved hypothetical membrane protein. Homology to pa4965 ao P. aeruginosa of 50% (trembl|Q9HUK0) Pfam: Retroviral aspartyl protease no signal peptide 1 TMHs; Conserved hypothetical protein; hypothetical protein	93454..93981	Azoarcus sp. BH72	4609625
YP_931587.1	CDS	rdgC	NC_008702.1	94431	95405	R	Required for efficient pilin antigenic variation; recombination associated protein	complement(94431..95405)	Azoarcus sp. BH72	4606206
YP_931588.1	CDS	azo0083	NC_008702.1	95476	95943	R	hypothetical protein	complement(95476..95943)	Azoarcus sp. BH72	4609699
YP_931589.1	CDS	rsuA	NC_008702.1	96022	96768	D	Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70) (16S pseudouridylate 516 synthase) (16S pseudouridine 516 synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.; Family membership; pseudouridylate synthase	96022..96768	Azoarcus sp. BH72	4606207
YP_931590.1	CDS	azo0085	NC_008702.1	97020	98186	D	Conserved hypothetical protein. Homology to RS04117 of R.solanacearum of 52% (tremble:Q8Y0H4) No domains predicted. No signal peptide. No TMHs; hypothetical protein	97020..98186	Azoarcus sp. BH72	4609830
YP_931591.1	CDS	efp	NC_008702.1	98247	98804	D	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P	98247..98804	Azoarcus sp. BH72	4606208
YP_931592.1	CDS	azo0087	NC_008702.1	98928	99359	D	Hypothetical secreted protein. Homology to RS00193 of R. solanacearum of 26% (tremble:Q8XVC9) PF02987, Late embryogenesis abundant protein;IPR004238;Different types of LEA proteins are expressed at different stages of late embryogenesis in higher plant seed embryos and under conditions of dehydration stress. The function of these proteins is unknown. No TMHs Signal peptide present; hypothetical protein	98928..99359	Azoarcus sp. BH72	4608662
YP_931593.1	CDS	uvrA1	NC_008702.1	99435	105044	D	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A). The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity). InterPro: Excinuclease ABC A subunit; High confidence in function and specificity; putative excinuclease ABC subunit	99435..105044	Azoarcus sp. BH72	4606209
YP_931594.1	CDS	azo0089	NC_008702.1	105090	105788	D	Conserved hypothetical hydrogenase cytochrome b-type subunit. Homology to C. vinosum of 56% (trembl|Q46471). Involved in electron transfer from hydrogen to oxygen. probable signal peptide probable 4 TMHs; Family membership; hydrogenase cytochrome b-type subunit	105090..105788	Azoarcus sp. BH72	4610080
YP_931595.1	CDS	cycA1	NC_008702.1	105850	106314	R	Probable cytochrome c'. Homology to cycA of C. vinosum of 61% (sprot|CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. Pfam: Cytochrome c. signal peptide no TMHs; Function unclear; cytochrome c'	complement(105850..106314)	Azoarcus sp. BH72	4606210
YP_931596.1	CDS	azo0091	NC_008702.1	106574	108199	D	Methyl-accepting chemotaxis protein,; Specificity unclear; methyl-accepting chemotaxis protein	106574..108199	Azoarcus sp. BH72	4608548
YP_931597.1	CDS	mucD1	NC_008702.1	108207	109646	R	Probable serine protease. Homology to mucD of P. aeruginosa of 55% (AAC43718). Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs; High confidence in function and specificity; serine protease MucD	complement(108207..109646)	Azoarcus sp. BH72	4606211
YP_931598.1	CDS	irgA1	NC_008702.1	109778	111763	R	23% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1.; High confidence in function and specificity; putative TonB-dependent receptor	complement(109778..111763)	Azoarcus sp. BH72	4609283
YP_931599.1	CDS	oxyR	NC_008702.1	111975	112913	D	oxyR, Hydrogen peroxide-inducible genes activator. BELONGS TO THE LYSR FAMILY OF TRANSCRIPTIONAL REGULATORS REQUIRED FOR THE INDUCTION OF A REGULON OF HYDROGEN PEROXIDE INDUCIBLE GENES SUCH AS CATALASE GLUTATHIONE-REDUCTASE ETC. (BY SIMILARITY). mreB: cell shape determining protein M 51% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity; putative oxyR	111975..112913	Azoarcus sp. BH72	4609087
YP_931600.1	CDS	azo0095	NC_008702.1	112981	115554	R	decatenates replicating daughter chromosomes; DNA topoisomerase III	complement(112981..115554)	Azoarcus sp. BH72	4609464
YP_931601.1	CDS	azo0096	NC_008702.1	115666	116133	R	Protein smg homolog, 45% identity (65% similarity) to SwissProt;P30853 43% identity to SwissProt;Q8X8F6,E.coli smg protein. Has PF04361(IPR007456):Protein of unknown function (DUF494);Members of this family of uncharacterised proteins are often named Smg. No signal peptide or TMH reported present.; hypothetical protein	complement(115666..116133)	Azoarcus sp. BH72	4606212
YP_931602.1	CDS	drpA	NC_008702.1	116194	117312	R	Putative DNA processing protein DrpA (Smf protein). Homology to drpA of H. influcenzae The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation InterPro: SMF family Tigerfam: dprA: DNA processing protein DprA,putative Pfam SMF family no signal peptide no TMHs; Family membership; putative DNA processing protein DrpA	complement(116194..117312)	Azoarcus sp. BH72	4606213
YP_931603.1	CDS	azo0098	NC_008702.1	117316	118503	R	Conseved hypothetical membrane protein. Homology to RSO2271 of R. solanacearum of 36% (trembl|Q8Y3B1(SRS)). Pfam: Lysin motif (SM00257) This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. No signal peptide 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(117316..118503)	Azoarcus sp. BH72	4608652
YP_931604.1	CDS	def	NC_008702.1	118530	119033	D	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase	118530..119033	Azoarcus sp. BH72	4606214
YP_931605.1	CDS	fmt	NC_008702.1	119079	120044	D	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase	119079..120044	Azoarcus sp. BH72	4608616
YP_931606.1	CDS	htpX	NC_008702.1	120104	120946	D	Putative protease HtpX Homolog to htpX of E. coli of 30% (AAA62779) InterPro: Peptidase family M48 (IPR001915) Pfam: Peptidase family M48 signal peptide TMHs3; Family membership; M48 family peptidase	120104..120946	Azoarcus sp. BH72	4608815
YP_931607.1	CDS	helX	NC_008702.1	120960	121487	D	Putative thiol:disulfide oxidoreductase. Homology to helX of R. casulata of 35% Periplasmic protein thiol:disulphide oxidoreductase is involved in the biogenesis of c-type cytochromes as well as in disulphide bond formation in some periplasmic proteins. Tigrfam: dsbE: periplasmic protein thiol:disulfide signal peptide no TMHs; High confidence in function and specificity; putative thiol:disulfide oxidoreductase	120960..121487	Azoarcus sp. BH72	4609040
YP_931608.1	CDS	azo0103	NC_008702.1	121484	122596	D	Conserved hypothetical secreted protein. Homology to SMa0025 of S. meliloti of 46% pir|D95263(SRS). Pfam: Transglutaminase_like Superfamily signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	121484..122596	Azoarcus sp. BH72	4608979
YP_931609.1	CDS	azo0104	NC_008702.1	122689	123570	D	Conserved hypothetical secreted protein. Homology to ebA582 of Azoacrus sp EbN1 (trembl:Q5P8D6). No domains predicted. SignalP reporting signal peptid. no TMHs; Conserved hypothetical protein; hypothetical protein	122689..123570	Azoarcus sp. BH72	4606215
YP_931610.1	CDS	tpx	NC_008702.1	123626	124126	D	Probable thiol peroxidase. Homology to E. coli of 62% (sprot:TPX_ECOLI) Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity). Pfam: AhpC/TSA family no signal peptide no TMHs; High confidence in function and specificity; thiol peroxidase	123626..124126	Azoarcus sp. BH72	4606216
YP_931611.1	CDS	azo0106	NC_008702.1	124218	125105	D	Conserved hypothetical membrane protein. Homology to an orf of R. palustris (tremblnew|CAE28417). Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter InterPro: Integral membrane protein DUF6 Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHs; Conserved hypothetical protein; hypothetical protein	124218..125105	Azoarcus sp. BH72	4609965
YP_931612.1	CDS	azo0107	NC_008702.1	125118	125834	R	conserved hypothetical membrane proteins, 42% identity (59% similarity) to TrEMBL;Q73PF0 Has PF02592;Uncharacterized ACR, YhhQ family COG1738;IPR003744:This is a family of uncharacterized proteins. Conserved regions of hydrophobicity suggest that all members of the family may be integral membrane proteins. no signal peptide. 4 TMH.; Conserved hypothetical protein; hypothetical protein	complement(125118..125834)	Azoarcus sp. BH72	4606217
YP_931613.1	CDS	azo0108	NC_008702.1	126088	127293	D	Conserved hypothetical secreted protein. Homology to XCC0740 of Xanthomonas campestris of 33% (trembl|Q8PCI6(SRS) Pfam: Glycosyl hydrolases family 2,TIM barrel domain This family contains beta-galactosidase,beta-mannosidase and beta-glucuronidase activities. No TMHs Signal peptide: present.; Conserved hypothetical protein; hypothetical protein	126088..127293	Azoarcus sp. BH72	4606218
YP_931614.1	CDS	yihZ	NC_008702.1	127357	127812	D	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase	127357..127812	Azoarcus sp. BH72	4606219
YP_931615.1	CDS	azo0110	NC_008702.1	127825	128703	R	Pirin-like protein. TREMBL:Q8P799: 52% identity,65% similarity. InterPro: DUF209 his region is found the C-terminal half of the Pirin protein. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body although it is expressed most strongly in the liver and heart. Pirin is known to be a nuclear protein, exclusively localised within the nucleoplasma and predominantly concentrated within dot-like subnuclear structures. A tomato homologue of human Pirin has been found to be induced during programmed cell death. Human Pirin interacts with Bcl-3 and NFI and hence is probably involved in the regulation of DNA transcription and replication. It appears to be an Fe(II)-containing member of the Cupin superfamil InterPro:IPR007113; Cupin_sup. IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam PF02678; Pirin; 1. PF05726; Pirin_C molyb_syn: molybdenum cofactor synthesis Absence of transmembrane helices (TMHMM predicted); Function unclear; pirin-related protein	complement(127825..128703)	Azoarcus sp. BH72	4610186
YP_931616.1	CDS	adhA	NC_008702.1	128838	129824	D	Putative Alcohol dehydrogenase. Homology to adh-HT of B. stearothermophilus (sprot|ADH3_BACST) THERMOSTABLE AND THERMOPHILIC NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. BEARS MAINLY AN ETHANOL-DEHYDROGENASE ACTIVITY. CATALYTIC ACTIVITY:An alcohol + NAD(+) = an aldehyde or ketone + NADH. COFACTOR: Binds 2 zinc ions per subunit (By similarity). Pfam: Zinc-binding dehydrogenase Tirgfam: tdh: L-threonine 3-dehydrogenase no signal peptide no TMHs; Family membership; putative alcohol dehydrogenase	128838..129824	Azoarcus sp. BH72	4606220
YP_931617.1	CDS	gstR1	NC_008702.1	129841	130737	R	Putative transcriptional regulator. Homology to gstR of R. leguminosarum of 37% (tremble:Q52827). Has PF00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family.IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC,iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR,nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini. Has PF03466, LysR substrate binding domain;IPR005119, LysR_subst; The structure of this domain is known and is; High confidence in function and specificity; putative transcriptional regulator	complement(129841..130737)	Azoarcus sp. BH72	4608279
YP_931618.1	CDS	gstA	NC_008702.1	130842	131489	D	Probabe glutathione transferase. Homology to gstA of R. leguminosarum of 58% (sprot:GSTA_RHILE) Conjugation of reduced glutathione to a variety of targets. Pfam: PF02798, GST_N, Glutathione S-transferase, N-terminal domain; PF00043, GST_C, Glutathione S-transferase, C-terminal domain Interpro: IPR004045, GST_Nterm; IPR004046,GST_Cterm; no signal peptide no TMHs; High confidence in function and specificity; glutathione transferase	130842..131489	Azoarcus sp. BH72	4608959
YP_931619.1	CDS	azo0114	NC_008702.1	131492	132490	D	Conserved hypothetical protein. Homology to bp2124 of B. pertussis of 48% (trembl|Q7VWS5). Pfam: Pyridoxamine 5-phosphate oxidase no signal peptide no TMHs; hypothetical protein	131492..132490	Azoarcus sp. BH72	4608957
YP_931620.1	CDS	azo0115	NC_008702.1	132910	133359	R	MaoC protein (Phenylacetic acid degradation protein paaZ). Entry name :- TREMBL:Q8XXS0 Prim. accession # Q8XXS0 InterPro:-IPR002539; MaoC_dehydratas. Pfam:-PF01575; MaoC_dehydratas; 1. Identities = 77/145 (53%) Number of predicted TMHs: 0; hypothetical protein	complement(132910..133359)	Azoarcus sp. BH72	4606221
YP_931621.1	CDS	amn	NC_008702.1	133377	134873	R	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase	complement(133377..134873)	Azoarcus sp. BH72	4606222
YP_931622.1	CDS	braF	NC_008702.1	135086	135853	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XU49 (72%) and to sprot|BRAF_PSEAE (40%). Pfam: ABC transporter Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	135086..135853	Azoarcus sp. BH72	4608311
YP_931623.1	CDS	azo0118	NC_008702.1	135870	136592	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7W5F6 (63%) and to trembl|Q8U8G7 (59%). Pfam (PF00005): ABC transporter Smart (SM00382): ATPase superfamily; Specificity unclear; ABC transporter ATP-binding protein	135870..136592	Azoarcus sp. BH72	4608405
YP_931624.1	CDS	azo0119	NC_008702.1	136627	137841	D	ABC transporter substrate binding proteins count to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q8XU51 (58%) and to tremblnew|CAE27314 (45%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; ABC transporter substrate-binding protein	136627..137841	Azoarcus sp. BH72	4606223
YP_931625.1	CDS	azo0120	NC_008702.1	137898	138782	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q92LQ5 (71%) and to trembl|Q8XU52 (69%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix.; Specificity unclear; ABC transporter permease	137898..138782	Azoarcus sp. BH72	4606224
YP_931626.1	CDS	livM1	NC_008702.1	138807	139763	D	Putative branched-chain amino acid transport permease. Homology to livM of S. typhimurium of 25%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: branch-chain amino acid transport system probable signal peptide probable 6 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	138807..139763	Azoarcus sp. BH72	4606225
YP_931627.1	CDS	azo0122	NC_008702.1	139919	141091	R	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N	complement(139919..141091)	Azoarcus sp. BH72	4609158
YP_931628.1	CDS	azo0123	NC_008702.1	141038	141463	D	putative threonine efflux protein	141038..141463	Azoarcus sp. BH72	4606226
YP_931629.1	CDS	azo0124	NC_008702.1	141533	141742	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted signal peptide no TMHs; hypothetical protein	141533..141742	Azoarcus sp. BH72	4606227
YP_931630.1	CDS	azo0125	NC_008702.1	141717	142061	D	Conserved hypothetical secreted protein,; Conserved hypothetical protein; hypothetical protein	141717..142061	Azoarcus sp. BH72	4606228
YP_931631.1	CDS	azo0126	NC_008702.1	142061	142369	D	Conserved hypothetical protein with 74% similarity(57% identity)to Conserved hypothetical protein [Sinorhizobium meliloti]. No Signal peptide reported to be present. No TMH reported to be present. Has PF07045,Protein of unknown function (DUF1330)This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown. TIGRFAM:acolac_sm: acetolactate synthase,small s; Family membership; hypothetical protein	142061..142369	Azoarcus sp. BH72	4606229
YP_931632.1	CDS	azo0127	NC_008702.1	142468	142659	D	Hypothetical protein, 40% identity to TrEMBL;Q73S36 Weak Homology with most protein hits in the database. No Domains/Features/Motifs predicted present.; hypothetical protein	142468..142659	Azoarcus sp. BH72	4606230
YP_931633.1	CDS	azo0128	NC_008702.1	142690	143106	R	Conserved hypothetical membrane protein, 50% identity (62% similarity) to TrEMBL;Q7NQ67. No domains predicted TMHMM2 reporting 1 TMH's present. No signal peptide reported present.; Conserved hypothetical protein; hypothetical protein	complement(142690..143106)	Azoarcus sp. BH72	4606231
YP_931634.1	CDS	tap	NC_008702.1	143294	144907	D	The Tap (taxis toward peptides) receptor and the periplasmic dipeptide-binding protein (DBP) of Escherichia coli together mediate chemotactic responses to dipeptides. Similar trembl|Q7P0E0 (32%) and to SWISSPROT:MCPC_SALTY (23%). Pfam(PF00015): Bacterial chemotaxis sensory transducer Pfam (PF00672):HAMP domain TMHMM reporting two TMH. SignalP reporting Signalpeptid.; Specificity unclear; putative dipeptide chemoreceptor	143294..144907	Azoarcus sp. BH72	4606232
YP_931635.1	CDS	nahY	NC_008702.1	145152	146765	D	The ability of bacteria to recognize and swim toward aromatic hydrocarbons is possibly an important prelude to their degradation. In Pseudomonas putida G7,NahY is the receptor required for the chemotaxis to naphthalene. Similar to trembl|Q7NU44 (38%) and to trembl|Q7NY58 (33%). Smart: HAMP domain Pfam (PF00015): Methyl-accepting chemotaxis protein (MCP) signalling domain SignalP reporting Signal Peptide.; Specificity unclear; putative aromatic hydrocarbon chemotaxis transducer	145152..146765	Azoarcus sp. BH72	4609915
YP_931636.1	CDS	dmpI	NC_008702.1	146889	147092	D	Probable tautomerase lin2709 (EC 5.3.2.2). TREMBL:Q7UE84: 67% identity, 86% similarity InterPro:IPR004370; Taut. ProDom: PD404143 InterPro: 4-oxalocrotonate tautomerase taut: 4-oxalocrotonate tautomerase No signal peptide no TMH's; High confidence in function and specificity; 4-oxalocrotonate tautomerase	146889..147092	Azoarcus sp. BH72	4609326
YP_931637.1	CDS	azo0132	NC_008702.1	147273	148154	D	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	147273..148154	Azoarcus sp. BH72	4608628
YP_931638.1	CDS	ilvE1	NC_008702.1	148401	149321	D	Branched-chain amino acid aminotransferase (EC 2.6.1.42) (BCAT). Acts on leucine isoleucine and valine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity; branched-chain-amino-acid transaminase	148401..149321	Azoarcus sp. BH72	4606233
YP_931639.1	CDS	ydaM	NC_008702.1	149318	150751	R	Hypothetical response regulator, TREMBL: trembl|Q7MSI2 (24% Wolinella succinogenes, hypothetical protein ws0414) InterPro: IPR001610 PAC. IPR000014 PAS. IPR001789 Response_reg. IPR000160 GGDEF. Pfam: PF00990 GGDEF domain. PF00072 Response_reg. PF00785 PAC. PF00989 PAS. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box.; Conserved hypothetical protein; putative response regulator	complement(149318..150751)	Azoarcus sp. BH72	4609072
YP_931640.1	CDS	azo0135	NC_008702.1	150748	151149	R	Putative response regulator; putative response regulator	complement(150748..151149)	Azoarcus sp. BH72	4610163
YP_931641.1	CDS	azo0136	NC_008702.1	151184	153406	R	Putative hybrid sensor and regulator protein; putative hybrid sensor and regulator protein	complement(151184..153406)	Azoarcus sp. BH72	4606234
YP_931642.1	CDS	amiC1	NC_008702.1	153403	154701	R	Aliphatic amidase expression-regulating protein,AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to sprot|AMIC_PSEAE (31%) and to trembl|P74390 (50%).Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative aliphatic amidase expression-regulating protein	complement(153403..154701)	Azoarcus sp. BH72	4606235
YP_931643.1	CDS	azo0138	NC_008702.1	154860	155846	D	Conserved hypothetical protein.Similarity to b.subtilis bmru and to synechocystis pcc 6803 sll0036. Identities = 29/85 (34%) Entry name SWISSPROT:YEGS_ECOLI Prim. accession # P76407 InterPro IPR005218; Cons_hypoth147. IPR001206; DAGKc. Pfam PF00781; DAGKc; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; hypothetical protein	154860..155846	Azoarcus sp. BH72	4608308
YP_931644.1	CDS	cpdA	NC_008702.1	155860	156708	D	Serine/threonine (S/T) phosphatases catalyse the dephosphorylation of phosphoserine and phosphothreonine residues. In mammalian tissues four different types of PP have been identified and are known as PP1, PP2A, PP2B and PP2C. Except for PP2C, these enzymes are evolutionary related. The catalytic regions of the proteins are well conserved TREMBL:Q7VZQ9: 41% identity, 50% similarity InterPro:IPR004843; M-ppestrase. Pfam:PF00149; Metallophos InterPro: Serine/threonine specific protein phosphatase No transmembrane helices sbcd: exonuclease SbcD; High confidence in function and specificity; phosphodiesterase	155860..156708	Azoarcus sp. BH72	4606236
YP_931645.1	CDS	azo0140	NC_008702.1	156692	157861	R	Conserved hypothetical protein. Homology to an orf of Ralstonia eutropha of 61% (ZP_00167955). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(156692..157861)	Azoarcus sp. BH72	4608525
YP_931646.1	CDS	gidA	NC_008702.1	158045	159949	D	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA	158045..159949	Azoarcus sp. BH72	4606237
YP_931647.1	CDS	gidB	NC_008702.1	159946	160584	D	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB	159946..160584	Azoarcus sp. BH72	4608876
YP_931648.1	CDS	parA1	NC_008702.1	160716	161486	D	putative chromosome partitioning protein; High confidence in function and specificity; ParA family protein	160716..161486	Azoarcus sp. BH72	4608877
YP_931649.1	CDS	azo0144	NC_008702.1	161496	161789	D	Hypothetical protein MJ0435. trembl:Q8DGT1:51% identity, 64% similarity InterPro: IPR002934; NTP_transf. Pfam: PF01909; NTP_transf_2 No signal peptide (Signal P predicted) No transmembrane helices (TMHMM predicted). hstdl_phs_rel: histidinol phosphatase-r; Specificity unclear; nucleotidyltransferase	161496..161789	Azoarcus sp. BH72	4609497
YP_931650.1	CDS	azo0145	NC_008702.1	161786	162148	D	Conserved hypothetical secreted protein. Homology to TLL2231 of Thermosynechococcus elongatus of 34% (tremble:Q8DGT2). Signal peptide present. No TMH reported present. Has (IPR008201)PF01934 Protein of unknown function DUF86;The function of members of this family is unknown.; Conserved hypothetical protein; hypothetical protein	161786..162148	Azoarcus sp. BH72	4606238
YP_931651.1	CDS	parB	NC_008702.1	162150	163013	D	Probable chromosome partitioning protein,; High confidence in function and specificity; chromosome partitioning protein ParB	162150..163013	Azoarcus sp. BH72	4606239
YP_931652.1	CDS	azo0147	NC_008702.1	163114	165879	R	Conserved hypothetical membrane protein. Homology to RS05051 of Ralstonia solanacearum of 45% (trembl|Q8Y1A4(SRS)). TMHMM2 reporting the presence of 26 TMH's. Signal P reporting Signal Peptide present. Coils2 program reporting presence of Coiled coil.; Conserved hypothetical protein; hypothetical protein	complement(163114..165879)	Azoarcus sp. BH72	4609500
YP_931653.1	CDS	azo0148	NC_008702.1	165901	167784	R	Similar to the Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-gpe acyltransferase); acyl-acyl carrier protein synthetase (acyl-acp synthetase)].Plays a role in lysophospholipid acylation. 25% Acyltransferase.IPR000873; AMP-bind. Pfam:PF01553; Acyltransferase; 1.PF00501; AMP-binding; 1. TMhelix:10; Function unclear; putative acyltransferase family protein	complement(165901..167784)	Azoarcus sp. BH72	4606240
YP_931654.1	CDS	uxuA	NC_008702.1	167781	169031	R	tremblnew|AAR36422:35% identity, 46% similarity EMBL:AE017218; AAR36422.1; TIGR:GSU3030; This Fe2+-requiring enzyme plays a role in D-glucuronate catabolism in Escherichia coli. Mannonate dehydratase converts D-mannonate to 2-dehydro-3-deoxy-D-gluconate. An apparent equivalog is found in a glucuronate utilization operon in Bacillus stearothermophilus T-6. Interpro:IPR004628;Man_dehyd SignalP predicted signal peptide present. No. of transmembrane helices: 1 (TMHMM predicted) pyrC_dimer: dihydroorotase homodimeric; Specificity unclear; putative mannonate dehydratase	complement(167781..169031)	Azoarcus sp. BH72	4606241
YP_931655.1	CDS	aas	NC_008702.1	169028	171166	R	AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Acyltransferase. TIGRFAM (TIGR00530): 1-acyl-sn-glycerol-3-phosphate acyltransferases. SignalP reporting signal peptide.; High confidence in function and specificity; bifunctional Aas protein	complement(169028..171166)	Azoarcus sp. BH72	4610086
YP_931656.1	CDS	smtB	NC_008702.1	171247	171558	R	Putative transcriptional repressor,; High confidence in function and specificity; putative transcriptional repressor	complement(171247..171558)	Azoarcus sp. BH72	4608243
YP_931657.1	CDS	azo0152	NC_008702.1	171735	172085	D	Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein; hypothetical protein	171735..172085	Azoarcus sp. BH72	4609878
YP_931658.1	CDS	atpB	NC_008702.1	172088	172936	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A	172088..172936	Azoarcus sp. BH72	4606242
YP_931659.1	CDS	atpE	NC_008702.1	172992	173237	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C	172992..173237	Azoarcus sp. BH72	4608367
YP_931660.1	CDS	atpF	NC_008702.1	173279	173752	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B	173279..173752	Azoarcus sp. BH72	4608370
YP_931661.1	CDS	atpH	NC_008702.1	173756	174289	D	putive ATP synthase delta chain. Homology to atpH of E. coli of 32% (sprot|ATPD_ECOLI). Key component of the F-type ATPases (EC 3.6.3.14). The ATPase has 2 components,CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha, beta,gamma, delta, epsilon. CF(0) has three main subunits: a, b and c. Subunit delta seems to be part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) into CF(1) or is implicated in proton conduction. InterPro: ATP synthase delta (OSCP) subunit (IPR000711) Pfam: ATP synthase delta (OSCP) subunit no signal peptide no TMHs; High confidence in function and specificity; putative ATP synthase delta chain	173756..174289	Azoarcus sp. BH72	4608371
YP_931662.1	CDS	atpA	NC_008702.1	174303	175841	D	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha	174303..175841	Azoarcus sp. BH72	4608373
YP_931663.1	CDS	atpG	NC_008702.1	175863	176732	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma	175863..176732	Azoarcus sp. BH72	4608366
YP_931664.1	CDS	atpD	NC_008702.1	176757	178157	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta	176757..178157	Azoarcus sp. BH72	4608372
YP_931665.1	CDS	atpC	NC_008702.1	178210	178635	D	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon	178210..178635	Azoarcus sp. BH72	4608369
YP_931666.1	CDS	azo0161	NC_008702.1	178705	179283	R	Conserved hypothetical protein. Homology to rsc0460 of R. solanacearum of 39% (trembl|Q8Y276(SRS) Pfam: DUF1243 This family consists of a number of hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown. no signal peptide no TMHs; hypothetical protein	complement(178705..179283)	Azoarcus sp. BH72	4608368
YP_931667.1	CDS	ubiE1	NC_008702.1	179327	180064	R	Ubiquinone/menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-). Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). InterPro: ubiE/COQ5 methyltransferase hemK_rel_arch: methylase putative; High confidence in function and specificity; ubiquinone/menaquinone biosynthesis methyltransferase	complement(179327..180064)	Azoarcus sp. BH72	4606243
YP_931668.1	CDS	azo0163	NC_008702.1	180072	180494	R	Conserved hypothetical protein. Homology to rs04443 of R. solanacearum of 69% (trembl|Q8Y279). Pfam: PF06155,Protein of unknown function (DUF971) Interpro: IPR010376; This family consists of several short bacterial proteins and one sequence (Q8RZ62) from Oryza sativa. The function of this family is unknown. No Signal Peptide. No TMH present.; hypothetical protein	complement(180072..180494)	Azoarcus sp. BH72	4610058
YP_931669.1	CDS	phoB	NC_008702.1	180644	181354	D	Phosphate regulon transcriptional regulatory protein,; High confidence in function and specificity; phosphate regulon transcriptional regulatory protein	180644..181354	Azoarcus sp. BH72	4606244
YP_931670.1	CDS	phoR	NC_008702.1	181446	182717	D	Phosphate regulon sensor protein, 3 Signal P reporting signal peptide TMHMM reporting 1 transmembrane helices. MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM PHOR/PHOB INVOLVED IN THE PHOSPHATE REGULON GENES EXPRESSION. PHOR MAY FUNCTION AS A MEMBRANE-ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES PHOB IN RESPONSE TO ENVIRONMENTAL SIGNALS.; High confidence in function and specificity; phosphate regulon sensor protein	181446..182717	Azoarcus sp. BH72	4609550
YP_931671.1	CDS	azo0166	NC_008702.1	182683	184287	R	Conserved hypothetical protein. Homology to ebA3023 of Azoarcus sp. EbN1 of 61% (trembl:Q5P4D4). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(182683..184287)	Azoarcus sp. BH72	4609551
YP_931672.1	CDS	azo0167	NC_008702.1	184317	184733	R	55% HIT. Pfam:PF01230; HIT; 1. The Histidine Triad (HIT) motif, His-phi-His-phi-His-phi-phi (phi, a hydrophobic amino acid) was identified as being highly conserved in a variety of organisms.; hypothetical protein	complement(184317..184733)	Azoarcus sp. BH72	4606245
YP_931673.1	CDS	azo0168	NC_008702.1	184801	185625	R	Conserved hypothetical glutamine amidotransferases class-II (Gn-AT), YafJ-type. Homology to ebA3026 of Azoarcus sp. EbN1 of 75% (gnl|keqq|eba:ebA3026(KEGG)). Pfam: Glutamine amidotransferases class-II. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has an Ntn hydrolase; Conserved hypothetical protein; glutamine amidotransferases class-II-like protein	complement(184801..185625)	Azoarcus sp. BH72	4606246
YP_931674.1	CDS	azo0169	NC_008702.1	185689	186207	R	Conserved hypothetical secreted protein. Homology to bll7463 of B. japonicum of 30% (tremble:Q89DH6). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(185689..186207)	Azoarcus sp. BH72	4606247
YP_931675.1	CDS	gatB	NC_008702.1	186300	187760	R	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B	complement(186300..187760)	Azoarcus sp. BH72	4606248
YP_931676.1	CDS	azo0171	NC_008702.1	187818	188330	R	Conserved hypothetical secreted protein. Homology to an orf of Dechloromonas aromatica of 41% (gi|46141061|ref|ZP_00152875.2|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide present. NO TMH present.; Conserved hypothetical protein; hypothetical protein	complement(187818..188330)	Azoarcus sp. BH72	4608862
YP_931677.1	CDS	gatA	NC_008702.1	188336	189799	R	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A	complement(188336..189799)	Azoarcus sp. BH72	4606249
YP_931678.1	CDS	gatC	NC_008702.1	189852	190139	R	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C	complement(189852..190139)	Azoarcus sp. BH72	4608861
YP_931679.1	CDS	mreB	NC_008702.1	190256	191299	D	functions in MreBCD complex in some organisms; rod shape-determining protein MreB	190256..191299	Azoarcus sp. BH72	4608863
YP_931680.1	CDS	mreC	NC_008702.1	191345	192262	D	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC	191345..192262	Azoarcus sp. BH72	4609272
YP_931681.1	CDS	mreD	NC_008702.1	192266	192787	D	Rod shape-determining protein mreD. Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.; High confidence in function and specificity; rod shape-determining protein	192266..192787	Azoarcus sp. BH72	4609273
YP_931682.1	CDS	pbpA	NC_008702.1	192797	194686	D	Penicillin-binding protein 2 (PBP-2). CELL WALL FORMATION; PBP2 IS RESPONSIBLE FOR THE DETERMINATION OF THE ROD SHAPE OF THE CELL. ITS SYNTHESIZE CROSS- LINKED PEPTIDOGLYCAN FROM THE LIPID INTERMEDIATES. InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity; penicillin-binding protein	192797..194686	Azoarcus sp. BH72	4609274
YP_931683.1	CDS	rodA	NC_008702.1	194683	195819	D	Rod shape-determining protein rodA. THIS IS ONE OF THE PROTEINS RESPONSIBLE FOR THE ROD SHAPE OF THE CELL. IT IS REQUIRED FOR THE EXPRESSION OF THE ENZYMATIC ACTIVITY OF PBP2 WHICH IS THOUGHT TO SYNTHESIZE PEPTIDOGLYCAN IN THE STEP OF INITIATION OF CELL ELONGATION.; High confidence in function and specificity; rod shape-determining protein	194683..195819	Azoarcus sp. BH72	4609502
YP_931684.1	CDS	rlpA	NC_008702.1	195800	196840	D	RlpA-like protein precursor.; Function unclear; lipoprotein	195800..196840	Azoarcus sp. BH72	4609756
YP_931685.1	CDS	dacC	NC_008702.1	196966	198096	D	Probable D-alanyl-D-alanine carboxypeptidase. Homology to dacD of E. coli of 41% (sprot|DACD_ECOLI) Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Pfam: D-alanyl-D-alanine carboxypeptidase signal peptide no TMHs; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase	196966..198096	Azoarcus sp. BH72	4609729
YP_931686.1	CDS	daaA	NC_008702.1	198136	198993	D	D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity; D-alanine transaminase	198136..198993	Azoarcus sp. BH72	4608577
YP_931687.1	CDS	azo0182	NC_008702.1	198986	199267	D	Conserved hypothetical protein. Homology to RSC0326 of Ralstonia solanacearum of 53% (tremble:Q8Y2K9) Has PF04359;Protein of unknown function (DUF493);This family includes several proteins of uncharacterised function. InterPro;IPR007454 No Signal Peptdie or TMH present.; hypothetical protein	198986..199267	Azoarcus sp. BH72	4608575
YP_931688.1	CDS	lipB	NC_008702.1	199264	199947	D	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B	199264..199947	Azoarcus sp. BH72	4606250
YP_931689.1	CDS	lipA	NC_008702.1	199989	200936	D	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase	199989..200936	Azoarcus sp. BH72	4609147
YP_931690.1	CDS	azo0185	NC_008702.1	201005	201682	D	Conserved hypothetical secreted protein. Homology to PP1518 of P. putida of 54% (trembl|Q88MQ2(SRS) No domains predicted Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	201005..201682	Azoarcus sp. BH72	4609146
YP_931691.1	CDS	rep	NC_008702.1	201756	203750	D	ATP-dependent DNA helicase rep (EC 3.6.1.-). REP HELICASE IS A SINGLE-STRANDED DNA-DEPENDENT ATPASE INVOLVED IN DNA REPLICATION; IT CAN INITIATE UNWINDING AT A NICK IN THE DNA. IT BINDS TO THE SINGLE-STRANDED DNA AND ACTS IN A PROGRESSIVE FASHION ALONG THE DNA IN THE 3 TO 5 DIRECTION (BY SIMILARITY). InterPro: UvrD/REP helicase.; High confidence in function and specificity; ATP-dependent DNA helicase	201756..203750	Azoarcus sp. BH72	4606251
YP_931692.1	CDS	azo0187	NC_008702.1	203837	204298	R	Conserved hypothetical cytochrome c5. Homology to vc0168 of V. cloreae of 38% (tremble: Q9KVH8). This basic c-type monoheme cytochrome has an unusally low redox potential compaired with mitochaondrial cytochrome C. It is reactive with cytochrome c oxidase but not with reductase. Pfam: Cytrochrome C probable signal peptide no TMHs; Family membership; cytochrome c5	complement(203837..204298)	Azoarcus sp. BH72	4609713
YP_931693.1	CDS	yueD	NC_008702.1	210014	210739	R	Putative benzil reductase. Homology to yueD of B. cereus of 32% (trembl|Q8RJ14). Belongs to the short-chain dehydrogenases/reductases (SDR) family. Transform benzil to (S)-benzion. Interpro: short-chain dehydrogenase/reductase SDR (IPR002198) Pfam: short chain dehydrogenase (PF00106) no signal peptide no TMHs; Family membership; short chain dehydrogenase	complement(210014..210739)	Azoarcus sp. BH72	4608231
YP_931694.1	CDS	azo0190	NC_008702.1	210838	211857	D	Conserved hypothetical protein. Homology to an orf of R. oxalatica of 31% (trembl|Q84ES1). Pfam: 37-kD nucleoid-associaed bacterial protein The Escherichia coli nucleoid contains DNA in a condensed but functional form. Analysis of proteins released from isolated spermidine nucleoids after treatment with DNase I reveals significant amounts of two proteins not previously detected in wild-type Escherichia coli. Partial amino-terminal sequencing has identified them as the products of rdgC and yejK. no signal peptide no TMHs; hypothetical protein	210838..211857	Azoarcus sp. BH72	4610199
YP_931695.1	CDS	azo0191	NC_008702.1	211933	212409	D	Entry name TREMBL:Q988L8 Prim. accession # Q988L8 InterPro IPR002539; MaoC_dehydratas. Identities = 63/131 (48%) Pfam PF01575; MaoC_dehydratas; 1. Number of predicted TMHs: 0 Probable MaoC protein (Phenylacetic acid degradation protein paaZ).; hypothetical protein	211933..212409	Azoarcus sp. BH72	4606253
YP_931696.1	CDS	apbA1	NC_008702.1	212402	213313	D	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Function unclear; 2-dehydropantoate 2-reductase	212402..213313	Azoarcus sp. BH72	4606254
YP_931697.1	CDS	trxC1	NC_008702.1	213319	213780	R	Probable protein-disulfide reductase. Homology with trxC of E. coli of 45% (AAB88587). Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin Tigrfam: redox_disulf_1: redox-active disulfide Pfam: Thioredoxin no TMHs no signal peptide; Family membership; protein-disulfide reductase	complement(213319..213780)	Azoarcus sp. BH72	4608325
YP_931698.1	CDS	hvrA1	NC_008702.1	213935	214333	D	Putative trans-acting regulatory protein. Homology to hvrA of R. capsulatus of 27% (sprot|HVRA_RHOCA). The histone-like nucleoid-structuring (H-NS) protein belongs to a family of bacterial proteins that play a role in the formation of nucleoid structure and affect gene expression under certain conditions (e.g. light). Interpro: Histone -like nucleotide-structuring protein H-Ns (IPR001801) Pfam: H-NS histone family no signal peptide no TMHs; Family membership; putative trans-acting regulatory protein HvrA	213935..214333	Azoarcus sp. BH72	4610043
YP_931699.1	CDS	azo0195	NC_008702.1	214378	214626	D	Conserved hypothetical secreted protein. Homology to CV3728 of Chromobacterium violaceum of 57% (tremble:Q7NRQ2) No domains predicted. No TMHs signal peptide present; Conserved hypothetical protein; hypothetical protein	214378..214626	Azoarcus sp. BH72	4609055
YP_931700.1	CDS	azo0196	NC_008702.1	214688	215722	R	Conserved hypothetical transcription factor,; Conserved hypothetical protein; hypothetical protein	complement(214688..215722)	Azoarcus sp. BH72	4606255
YP_931701.1	CDS	azo0197	NC_008702.1	215834	216118	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs; hypothetical protein	215834..216118	Azoarcus sp. BH72	4606256
YP_931702.1	CDS	pabB	NC_008702.1	216106	217965	R	Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear; para-aminobenzoate synthase component I	complement(216106..217965)	Azoarcus sp. BH72	4606257
YP_931703.1	CDS	sbcD	NC_008702.1	218051	219196	D	Exonuclease sbcD homolog. Probably involved in genetic recombination. InterPro: DNA repair exonuclease. sbcd: exonuclease SbcD.; High confidence in function and specificity; exonuclease SbcD	218051..219196	Azoarcus sp. BH72	4609487
YP_931704.1	CDS	sbcC	NC_008702.1	219193	222264	D	Nuclease sbcCD subunit C. SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity (By similarity). sbcc: exonuclease SbcC.; High confidence in function and specificity; exonuclease SbcC	219193..222264	Azoarcus sp. BH72	4609840
YP_931705.1	CDS	azo0201	NC_008702.1	222387	223202	R	Arylesterase (EC 3.1.1.2) (Aryl-ester hydrolase) pir:C75401:39% identity, 52% similarity:hydrolase-related protein - Deinococcus radiodurans . IS A BIFUNCTIONAL ENZYME CAPABLE OF BOTH ESTER HYDROLYSIS AND HALOGENATION. ACTS ON MANY PHENOLIC ESTERS. Pfam: PF00561: alpha/beta hydrolase fold (74-271) InterPro: IPR000073: Alpha/beta hydrolase fold IPR000379: Esterase/lipase/thioesterase Pfam:Zn binding dehydrogenase mobB: molybdopterin-guanine dinucleotid; Family membership; aryl-ester hydrolase	complement(222387..223202)	Azoarcus sp. BH72	4609839
YP_931706.1	CDS	azo0202	NC_008702.1	223457	224176	D	Conserved hypothetical protein. Homology only to r01975 of S. meliloti of 31% (trembl|Q92P21). no signal peptide no TMHs; hypothetical protein	223457..224176	Azoarcus sp. BH72	4606258
YP_931707.1	CDS	azo0203	NC_008702.1	224493	225563	D	TREMBL:Q82XH5: 33% identity, 44% similarity InterPro:IPR007404; DUF457. Pfam: PF04307; DUF457 fnt: formate/nitrite transporter Non-secretory protein with signal peptide probability of 0.391 TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein; hypothetical protein	224493..225563	Azoarcus sp. BH72	4606259
YP_931708.1	CDS	bmpA	NC_008702.1	225594	226691	R	Description:abc transporter periplasmic binding protein.This is a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. All of these proteins are outer membrane proteins and are thus antigenic in nature when possessed by the pathogenic members of the family Probable CD4+ T cell-stimulating antigen precursor. TREMBL: Q8XXD8: 64% identity, 79% similarity InterPro:IPR003760; Bmp. Pfam: PF02608; Bmp Secretory protein with high signal peptide probablity (Signal P predicted). No. of transmembrane helices: 1 (TMHMM predicted) prok_nadp_idh: isocitrate dehydrogenas; Specificity unclear; lipoprotein	complement(225594..226691)	Azoarcus sp. BH72	4606260
YP_931709.1	CDS	hipO1	NC_008702.1	226835	228079	R	Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7VUP2: 43% identity, 57% similarity InterPro; IPR002933; Peptidase_M20. InterPro; IPR010168; Pept_M20D_amidh. Pfam; PF01546; Peptidase_M20; 1. TIGRFAMs; TIGR01891; amidohydrolases TIGR00003: copper-ion-binding protein No signal peptide (Signal P predicted) No transmembrane helices present; High confidence in function and specificity; hippurate hydrolase	complement(226835..228079)	Azoarcus sp. BH72	4608400
YP_931710.1	CDS	azo0206	NC_008702.1	228076	228660	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(228076..228660)	Azoarcus sp. BH72	4608997
YP_931711.1	CDS	azo0207	NC_008702.1	228700	229056	D	Conserved hypothetical protein. Homology to bb1472 of B. bronchiseptica of 46% (trembl|Q7WMC0). Interpro: Protein of unknown function DUF861 (IPR008579). Pfam: Cupin_3 (former DUF861) (PFO5899). This family consists of several proteins which seem to be specific to plants and bacteria. The function of this family is unknown. No signal peptide. No TMHs; hypothetical protein	228700..229056	Azoarcus sp. BH72	4606261
YP_931712.1	CDS	azo0208	NC_008702.1	229064	229267	R	Hypothetical protein, 45% identity to TrEMBL;Q7U8P5. Weak Homology with hits. No domains,repeats, motifs or features predicted Present.; Function unclear; hypothetical protein	complement(229064..229267)	Azoarcus sp. BH72	4606262
YP_931713.1	CDS	agaE	NC_008702.1	229633	230862	R	Sarcosine oxidase,subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q88AX8 (49%) and to trembl|Q987J9 (43%). Pfam (PF01266): FAD dependent oxidoreductase Pfam (PF01494): FAD binding domain Pfam (PF00070): Pyridine nucleotide-disulphide oxidoreductase; Function unclear; sarcosine oxidase subunit beta	complement(229633..230862)	Azoarcus sp. BH72	4606263
YP_931714.1	CDS	ooxA	NC_008702.1	230859	232241	R	Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership; putative opine oxidase subunit A	complement(230859..232241)	Azoarcus sp. BH72	4608285
YP_931715.1	CDS	azo0211	NC_008702.1	232223	232552	R	hypothetical protein	complement(232223..232552)	Azoarcus sp. BH72	4609450
YP_931716.1	CDS	prp	NC_008702.1	232564	233067	R	Probable proline dehydrogenase transcriptional activator. Similar to sprot|PUTR_AGRTU (31% Agrobacterium tumefaciens, proline dehydrogenase transcriptional activator prp or putR) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; proline dehydrogenase transcriptional activator	complement(232564..233067)	Azoarcus sp. BH72	4606264
YP_931717.1	CDS	azo0213	NC_008702.1	233142	234524	R	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (78-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). bioA: adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Specificity unclear; hypothetical protein	complement(233142..234524)	Azoarcus sp. BH72	4609635
YP_931718.1	CDS	azo0214	NC_008702.1	235059	235934	R	Conserved hypothetical acetyltransferase. Homology to putative acetaltransferase (GNAT family) of P. syringae of 42% (trembl|Q88AY8). Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHs; Family membership; acetyltransferase	complement(235059..235934)	Azoarcus sp. BH72	4606265
YP_931719.1	CDS	aldH	NC_008702.1	236153	237637	D	Putative aldehyde dehydrogenase (NAD+) (EC 1.2.1.3). Homology to adlH of E. coli of 35% (sprot|DHAL_ECOLI). Aldehyde dehydrogenases (EC: 1.2.1.3 and EC: 1.2.1.5) are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity; putative aldehyde dehydrogenase (NAD+)	236153..237637	Azoarcus sp. BH72	4606266
YP_931720.1	CDS	hadL	NC_008702.1	237835	238500	D	Probable 2-haloalkanoic acid dehalogenase (EC 3.8.1.2) (L-2-haloacid dehalogenase) (Halocarboxylic acid halidohydrolase). TREMBL:Q92Y68: 68% identity, 82% similarity These proteins catalyze the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids [1]. They belong to the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases InterPro:IPR006328; HAD_II. IPR006388; HAD_SF_IA_v2. IPR005834; Hydrolase. Pfam PF00702; Hydrolase rpiB_lacA_lacB: sugar-phosphate isomer No signal peptide No transmembrane helices; High confidence in function and specificity; haloalkanoic acid dehalogenase	237835..238500	Azoarcus sp. BH72	4608295
YP_931721.1	CDS	ordL	NC_008702.1	238541	239833	D	This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase, D-aspartate oxidase. Similar to trembl|Q88AY5 (61%) and to sprot|ORDL_ECOLI (32%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site; Family membership; FAD dependent oxidoreductase family protein	238541..239833	Azoarcus sp. BH72	4608977
YP_931722.1	CDS	dppA	NC_008702.1	239850	241457	D	Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide periplasmic-binding protein dppA in E.coli. DIPEPTIDE-BINDING PROTEIN OF AN OSMOTIC-SHOCKABLE TRANSPORT SYSTEM. DPPA IS ALSO REQUIRED FOR PEPTIDE CHEMOTAXIS. InterPro: Bacterial extracellular solute-binding protein family 5 Signal peptide; Specificity unclear; putative dipeptide transport system periplasmic-binding protein	239850..241457	Azoarcus sp. BH72	4609456
YP_931723.1	CDS	dppB	NC_008702.1	241462	242418	D	Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease, DppB in E.coli.; Specificity unclear; putative dipeptide transport system permease	241462..242418	Azoarcus sp. BH72	4608643
YP_931724.1	CDS	dppC	NC_008702.1	242415	243290	D	Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease, DppC in E.coli.; Specificity unclear; ABC transporter permease	242415..243290	Azoarcus sp. BH72	4608644
YP_931725.1	CDS	dppD	NC_008702.1	243283	245109	D	Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system.; Specificity unclear; putative dipeptide transport system ATP-binding protein	243283..245109	Azoarcus sp. BH72	4608645
YP_931726.1	CDS	gabD1	NC_008702.1	245317	246789	D	Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of R. eutropha of 68% (AAF19796). Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity; succinate semialdehyde dehydrogenase	245317..246789	Azoarcus sp. BH72	4608646
YP_931727.1	CDS	azo0223	NC_008702.1	247001	247369	D	Conserved hypothetical secreted protein. Homology to an orf of Polaromonas sp. JS666 of 34% (ZP_00360285) . No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	247001..247369	Azoarcus sp. BH72	4608851
YP_931728.1	CDS	azo0224	NC_008702.1	247500	248717	D	Hypotethical outer membrane efflux protein. Homology to PA2525 of P. aeruginosa of 25%. signal peptide. no TMHs; outer membrane efflux protein	247500..248717	Azoarcus sp. BH72	4606267
YP_931729.1	CDS	azo0225	NC_008702.1	248714	249310	D	Hypothetical secreted protein. No homology to the data bank no domains predicted signal peptide no TMHs; hypothetical protein	248714..249310	Azoarcus sp. BH72	4606268
YP_931730.1	CDS	azo0226	NC_008702.1	249307	250452	D	Conserved hypothetical secreted protein. Homology to cc1787 of C. crescentus of 30% (trembl|Q9A7D6) no domains predicted signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	249307..250452	Azoarcus sp. BH72	4606269
YP_931731.1	CDS	czcA1	NC_008702.1	250466	253597	D	Cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA). In A.eutrophus has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.Czca and Czcb together would act in zinc efflux nearly as effectively as the complete czc efflux system (czcABC).Belongs to the acrb/acrd/acrf family. 41% similarity to the A.eutrophus CzcA protein. SWISSPROT:CZCA_ALCEU:P13511 InterPro: Heavy metal efflux pump CzcA. InterPro:IPR001036; Acrflvin_res.IPR004763: CzcA. Pfam:PF00873; ACR_tran; 1. InterPro:TIGR00914:Heavy metal efflux pump CzcA InterPro:PF00873:Acriflavin resistance protein Signal peptide: present.; High confidence in function and specificity; putative cation efflux system protein	250466..253597	Azoarcus sp. BH72	4606270
YP_931732.1	CDS	azo0228	NC_008702.1	253594	254088	D	Hypothetical protein, 32% identity to TrEMBL;Q82T66 No Signal Peptide/Features/Domains/TMH detected.; hypothetical protein	253594..254088	Azoarcus sp. BH72	4608569
YP_931733.1	CDS	fhuA1	NC_008702.1	254346	256517	D	In E.coli this receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin. Signal peptide.; Specificity unclear; ferrichrome-iron TonB-dependent receptor	254346..256517	Azoarcus sp. BH72	4606271
YP_931734.1	CDS	azo0230	NC_008702.1	256540	257289	D	Conserved hypothetical secreted protein. Homology to RPA1846 of R.palustris of 39% (trembl:Q6N8Q7). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	256540..257289	Azoarcus sp. BH72	4608760
YP_931735.1	CDS	azo0231	NC_008702.1	257937	259160	D	Conserved hypothetical membrane protein. Homology to SO1157 of Shewanella oneidensis of 50% (trembl|Q8EHR0(SRS)). No domains predicted. Signal peptide. 7 TMHs; Conserved hypothetical protein; hypothetical protein	257937..259160	Azoarcus sp. BH72	4606272
YP_931736.1	CDS	exbB1	NC_008702.1	259217	260059	D	Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 35%. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. PFam: MotA/TolQ/ExbB proton channel family signals peptide most probable 4 TMHs; Family membership; putative biopolymer transport protein ExbB	259217..260059	Azoarcus sp. BH72	4606273
YP_931737.1	CDS	exbD1	NC_008702.1	260085	260513	D	putative biopolymer transport protein ExbD. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton grandient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership; putative biopolymer transport protein ExbD	260085..260513	Azoarcus sp. BH72	4608696
YP_931738.1	CDS	exbD2	NC_008702.1	260535	260960	D	Putative biopolymer transport protein ExbD. Homology to exbD2 of X. campestris of 36% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership; putative biopolymer transport protein ExbD	260535..260960	Azoarcus sp. BH72	4608700
YP_931739.1	CDS	azo0235	NC_008702.1	260989	261636	D	Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	260989..261636	Azoarcus sp. BH72	4608701
YP_931740.1	CDS	add	NC_008702.1	261880	262902	R	Adenosine deaminase (Adenosine aminohydrolase). InterPro: Adenosine and AMP deaminase; High confidence in function and specificity; adenosine deaminase	complement(261880..262902)	Azoarcus sp. BH72	4606274
YP_931741.1	CDS	npd1	NC_008702.1	262974	263831	R	Putative NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog). Modulates the activities of several enzymes which are inactive in their acetylated form. Similar to SWISSPROT: sprot|NPD_AERPE (27% Aeropyrum pernix, NpdA or aq_2170) Pfam: PF02146 Sir2 family.; High confidence in function and specificity; putative NAD-dependent deacetylase	complement(262974..263831)	Azoarcus sp. BH72	4608278
YP_931742.1	CDS	azo0238	NC_008702.1	263828	264958	R	Hypothetical membrane protein no homology to the data bank no domains predicted no signal predicted 7 TMHs; hypothetical protein	complement(263828..264958)	Azoarcus sp. BH72	4609408
YP_931743.1	CDS	azo0239	NC_008702.1	264970	266250	R	Hypothetical protein, showing only very low similarity to known proteins (SWISSPROT: sprot|FRAH_ANASP; >10% Anabaena sp., FraH). Important Domains are: Pfam: PF00034 Cytochrome c. SMART: SM00438 ZnF_NFX TMHMM reporting 1 transmembrane helices.; hypothetical protein	complement(264970..266250)	Azoarcus sp. BH72	4606275
YP_931744.1	CDS	dctP1	NC_008702.1	266442	267473	D	Putative ABC transporter periplasmic binding protein, DctP: TRAP dicarboxylate transporter.Binds C4-dicarboxylates; part of the binding-protein- dependent transport system for uptake of c4-dicarboxylates. 28% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide:present. TMhelix:1; Specificity unclear; putative C4-dicarboxylate-binding periplasmic protein	266442..267473	Azoarcus sp. BH72	4606276
YP_931745.1	CDS	dctQ1	NC_008702.1	267570	268058	D	C4-dicarboxylate transport system,permease small protein,DctQ. The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:4.; High confidence in function and specificity; DctQ1 protein	267570..268058	Azoarcus sp. BH72	4608602
YP_931746.1	CDS	dctM1	NC_008702.1	268055	269338	D	TRAP-type C4-dicarboxylate transport system, large permease component, DctM.The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 34% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. Signal peptide: present. TMhelix:11.; Specificity unclear; TRAP-type C4-dicarboxylate transport system large permease	268055..269338	Azoarcus sp. BH72	4608608
YP_931747.1	CDS	uidR	NC_008702.1	269367	270011	R	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	complement(269367..270011)	Azoarcus sp. BH72	4608597
YP_931748.1	CDS	azo0244	NC_008702.1	270224	271426	D	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8XRL2 (55% identity); SWISSPROT:P31223 (53% identity). Pfam (PF00529): HlyD family secretion protein. SignalP predicting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership; membrane fusion protein	270224..271426	Azoarcus sp. BH72	4610067
YP_931749.1	CDS	azo0245	NC_008702.1	271438	274596	D	Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q8E8H2 (65% identity); SWISSPROT:P31224 (63% identity). InterPro (IPR001036): Acriflavin resistance protein. InterPro (IPR004764): Hydrophobe/amphiphile efflux-1 HAE1. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. Pfam (PF00873): AcrB/AcrD/AcrF family. TMHMM reporting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	271438..274596	Azoarcus sp. BH72	4606277
YP_931750.1	CDS	oprM1	NC_008702.1	274611	276014	D	Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 57%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Pfam: Outer membrane efflux protein signal peptide no TMHS; Family membership; outer membrane efflux protein	274611..276014	Azoarcus sp. BH72	4606278
YP_931751.1	CDS	bfr1	NC_008702.1	276172	276657	D	Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis. InterPro: Bacterioferritin. Non-secretory protein; High confidence in function and specificity; putative bacterioferritin	276172..276657	Azoarcus sp. BH72	4609453
YP_931752.1	CDS	dksA1	NC_008702.1	276847	277365	D	Probable dnaK suppressor protein,; High confidence in function and specificity; dnaK suppressor protein	276847..277365	Azoarcus sp. BH72	4608386
YP_931753.1	CDS	azo0249	NC_008702.1	277409	277567	D	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHS; hypothetical protein	277409..277567	Azoarcus sp. BH72	4608624
YP_931754.1	CDS	azo0250	NC_008702.1	277561	278289	R	Hypothetical flavodoxin reductase. Homology to the N-terminal part of bb4317 of B. bronchisptica of 40% (trembl|Q7WFF6). InterPro: Oxidoreductase FAD and NAD(P)-binding domain ((IPR001433); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidorectase FAD-binding domain; Oxidoreductase NAD-binding domain no signal peptide no TMHs; flavodoxin reductase	complement(277561..278289)	Azoarcus sp. BH72	4606279
YP_931755.1	CDS	azo0251	NC_008702.1	278417	279895	D	Conserved hypothetical membrane protein, 38% similarity to trEMBL;Q7WDT1,Putative membrane protein [BB4906] [Bordetella bronchiseptica (Alcaligenes bronchisepticus)]. TMHMM2 predicts 6 TMH's present. No signal peptide present.; Family membership; hypothetical protein	278417..279895	Azoarcus sp. BH72	4606280
YP_931756.1	CDS	azo0252	NC_008702.1	279963	281318	D	conserved hypothetical protein, 54% identity to TrEMBL;Q9JYD1 Hypothetical protein NMB1644 [NMB1644] [Neisseria meningitidis(serogroup B)]. Has PF00009:Elongation factor Tu GTP binding domain:IPR000795 ProtSyn_GTPbind: This domain contains a P-loop motif, also found in several other families such as Ras, Arf and Myosin_head. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains. Elongation factors belong to a family of proteins that promote the GTP-dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis,and catalyse the translocation of the synthesised protein chain from the A to the P site. The proteins are all relatively similar in the vicinity of their C-termini, and are also highly; hypothetical protein	279963..281318	Azoarcus sp. BH72	4606281
YP_931757.1	CDS	azo0253	NC_008702.1	281341	282051	R	Conserved hypothetical protein. Homology to MCA0921 of Methylococcus capsulatus of 54% (trembl:Q60AE3). N domains predicted. No TMHs. NO signal peptide.; hypothetical protein	complement(281341..282051)	Azoarcus sp. BH72	4606282
YP_931758.1	CDS	azo0254	NC_008702.1	282048	282746	R	Conserved polysaccharide deacetylase. Homology to rs03397 of R. solanacearum of 62% (trembl|Q8Y2A8). Interpro: Polysaccharide deacetylase (IPR002509). Pfam: Polysaccharide deacetylase (PF01522). The family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan. No signal peptide. No TMHs; Conserved hypothetical protein; polysaccharide deacetylase	complement(282048..282746)	Azoarcus sp. BH72	4606283
YP_931759.1	CDS	azo0255	NC_008702.1	282948	283649	R	Hypothetical protein. No good homology to the data bank. No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(282948..283649)	Azoarcus sp. BH72	4606284
YP_931760.1	CDS	azo0256	NC_008702.1	283646	286057	R	Conserved hypothetical membrane protein. Homology to rsc0429 of R. solanacearum of 52% (trembl|Q8Y2A7). Tigrfam: 2A0604s01: protein-export membrane protein signal peptide 10 TMHs; Function unclear; hypothetical protein	complement(283646..286057)	Azoarcus sp. BH72	4606285
YP_931761.1	CDS	azo0257	NC_008702.1	286054	286632	R	Conserved hypothetical secreted protein. Homology to RS03399 of R. solanacearum of 47% (trembl|Q8Y2A6(SRS)) No domains predicted. Signal Peptide present. No TMH reported.; Conserved hypothetical protein; hypothetical protein	complement(286054..286632)	Azoarcus sp. BH72	4606286
YP_931762.1	CDS	azo0258	NC_008702.1	286629	287561	R	Conserved hypothetical acetyltransferase. Homology to rsc0431 of R. solanacearum of 61% (trembl|Q8Y2A5) Pfam: Bacterial lipid A biosynthesis acetyltransferase no signal peptide no TMHs; Conserved hypothetical protein; acetyltransferase	complement(286629..287561)	Azoarcus sp. BH72	4606287
YP_931763.1	CDS	azo0259	NC_008702.1	287558	287869	R	Conserved hypothetical protein. Homology to xac 4098 of X. axonapodis of 36% (trembl|Q8PF87). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(287558..287869)	Azoarcus sp. BH72	4606288
YP_931764.1	CDS	azo0260	NC_008702.1	287866	289215	R	Entry name:- TREMBL:Q87EI7 InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 2. Identity :- 45% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; hypothetical protein	complement(287866..289215)	Azoarcus sp. BH72	4606289
YP_931765.1	CDS	azo0261	NC_008702.1	289232	289885	R	Conserved hypothetical membrane protein. Homology to rsc3402 of R. solanacearum of 46% (trembl|Q8Y2A3(SRS)) no domains predicted signal peptide 5 TMHs; Conserved hypothetical protein; hypothetical protein	complement(289232..289885)	Azoarcus sp. BH72	4606290
YP_931766.1	CDS	azo0262	NC_008702.1	289885	290169	R	Similar to TREMBL:Q9PFA7 (61% identity); TREMBL:Q87AD9 (61% identity); SWISSPROT:Q7VKH6 (34% identity).; Function unclear; ORF1; hypothetical protein	complement(289885..290169)	Azoarcus sp. BH72	4606291
YP_931767.1	CDS	azo0263	NC_008702.1	290292	291683	R	Probable sensor protein,; High confidence in function and specificity; two-component system histidine kinase	complement(290292..291683)	Azoarcus sp. BH72	4606292
YP_931768.1	CDS	qseB1	NC_008702.1	291680	292336	R	Transcriptional regulatory protein,; High confidence in function and specificity; transcriptional regulator	complement(291680..292336)	Azoarcus sp. BH72	4606293
YP_931769.1	CDS	azo0265	NC_008702.1	292491	292763	D	Conserved hypothetical secreted protein. Homology to bd0091 of B. bacteriovorus of 52% (tremblnew|CAE77770(SRS)). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein; hypothetical protein	292491..292763	Azoarcus sp. BH72	4609686
YP_931770.1	CDS	azo0266	NC_008702.1	292777	293298	D	Conserved hypothetical cytochrome b561 family protein. Homology to rsc2354 of R. solanacearum of 43% (trembl|Q8XWW6). Involved in electron transfer from hydrogen to oxygene. Pfam: Nickel-dependen hydrogenase b-type cytochrome no signal peptide probable 4 TMHs; Family membership; cytochrome b561 family protein	292777..293298	Azoarcus sp. BH72	4606294
YP_931771.1	CDS	czcB	NC_008702.1	293415	294473	D	Putative membrane fusion protein. Homology to cnrb of A. eutrophus of 30% (pir|F47056). Proteins of the MFP family function as auxiliary proteins or 'adaptors',connecting a primary porter in the cytoplasmic membrane of a Gram-negative bacterium with an outer membrane factor protein that serves a porin or channel function in the outer membrane. In A. eutrophus is this protein involved in cobalt and nickel resistance. No domains predicted. No signal peptide No TMHs; Family membership; putative membrane fusion protein	293415..294473	Azoarcus sp. BH72	4606295
YP_931772.1	CDS	czcA2	NC_008702.1	294470	297574	D	Cobalt-zinc-cadmium resistance protein CzcA (cation efflux system protein CzcA). In A.eutrophus has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.Czca and Czcb together would act in zinc efflux nearly as effectively as the complete czc efflux system (czcABC).Belongs to the acrb/acrd/acrf family. 41% similarity to the A.eutrophus CzcA protein. SWISSPROT:CZCA_ALCEU:P13511 InterPro: Heavy metal efflux pump CzcA. InterPro:IPR001036; Acrflvin_res.IPR004763: CzcA. Pfam:PF00873; ACR_tran; 1. InterPro:TIGR00914:Heavy metal efflux pump CzcA InterPro:PF00873:Acriflavin resistance protein Signal peptide: present.; High confidence in function and specificity; putative cation efflux system protein	294470..297574	Azoarcus sp. BH72	4608571
YP_931773.1	CDS	azo0269	NC_008702.1	297571	297885	D	Conserved hypothetical protein.30% identical to TrEMBL; Q89MS9. Signal Peptide present.; hypothetical protein	297571..297885	Azoarcus sp. BH72	4608570
YP_931774.1	CDS	azo0270	NC_008702.1	297885	299159	D	Hypothetical secreted protein. Homology to cnfc of Ralstonia sp CH34 of 28% (tremblnew|CAB82451(SRS). Pfam: outer membrane protein. Interpro: Type I antifreeze protein (IPR000104). singal peptide. no TMHs; hypothetical protein	297885..299159	Azoarcus sp. BH72	4606296
YP_931775.1	CDS	azo0271	NC_008702.1	299301	300887	R	Conserved hypothetical protein. Homology to Daro03000974 of Dechloromonas aromatica of 68% (gi|46140980|ref|ZP_00152750.2|(NBCI ENTREZ)). Pfam: Elongator protein 3, MiaB family, Radical SAM. This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases; Pfam: B12 binding domain. This domain binds to B12 (adenosylcobamide), it is found in several enzymes, such as glutamate mutase Q05488, methionine synthase Q99707 and methylmalonyl-CoA mutase. no signal peptide. no TMHs; hypothetical protein	complement(299301..300887)	Azoarcus sp. BH72	4606297
YP_931776.1	CDS	azo0272	NC_008702.1	301090	301368	R	Hypothetical protein. No homology to protein of similar size in the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	complement(301090..301368)	Azoarcus sp. BH72	4606298
YP_931777.1	CDS	sigW	NC_008702.1	301346	301972	R	Putative RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ.; High confidence in function and specificity; ECF family RNA polymerase sigma factor	complement(301346..301972)	Azoarcus sp. BH72	4606299
YP_931778.1	CDS	azo0274	NC_008702.1	301969	302409	R	Conserved hypothetical secreted protein. Homology to XCC0845 of X. campestris of 30% (trembl|Q8PC89). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(301969..302409)	Azoarcus sp. BH72	4609868
YP_931779.1	CDS	azo0275	NC_008702.1	302583	302924	D	Conserved hypothetical secreted protein. Homology to CC3220 of Caulobacter crescentus of 34% (trembl|Q9A3I4(SRS)) No domains predicted. Signal Peptide present. NO TMH present.; Conserved hypothetical protein; hypothetical protein	302583..302924	Azoarcus sp. BH72	4606300
YP_931780.1	CDS	azo0276	NC_008702.1	303050	303640	D	Putative Hypothetical protein. No Good homologous hits in the DB. No domains/features/signal peptide or motifs present.; hypothetical protein	303050..303640	Azoarcus sp. BH72	4606301
YP_931781.1	CDS	azo0277	NC_008702.1	303727	304134	D	Hypothetical protein. Weak Homology. 39% identity to TrEMBL;Q8EWG7. No domains, repeats, motifs or features present.; hypothetical protein	303727..304134	Azoarcus sp. BH72	4606302
YP_931782.1	CDS	azo0278	NC_008702.1	304110	304865	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs; hypothetical protein	complement(304110..304865)	Azoarcus sp. BH72	4606303
YP_931783.1	CDS	azo0279	NC_008702.1	305070	305825	D	Conserved hypothetical protein. Homology to BB1132 of B.bronchiseptica of 42% (tremble:Q7WNA8). No domains predicted. No Signal peptide or TMH present.; hypothetical protein	305070..305825	Azoarcus sp. BH72	4606304
YP_931784.1	CDS	azo0280	NC_008702.1	305877	308081	D	Conserved hypothetical membrane protein. Homology to rs03062 of R. solanacearum of 48% (tremble:Q8XQ05) no domains predicted signal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	305877..308081	Azoarcus sp. BH72	4606305
YP_931785.1	CDS	azo0281	NC_008702.1	308084	308728	D	Outer membrane protein A precursor. Homology with hypothetical transmembrane protein and probable outer membrane protein of 56% as well as with motB (flagellar motor protein B) from amino acid 84 of 34%. Pfam: OmpA no signal peptide probable 1 TMH; Conserved hypothetical protein; hypothetical protein	308084..308728	Azoarcus sp. BH72	4606306
YP_931786.1	CDS	azo0282	NC_008702.1	308721	309476	D	Conserved hypothetical protein. Homology to RS03060 of R.solanacearum of 35% (tremble:Q8XQ03) No domains predicted. No signal peptide or TMH present.; hypothetical protein	308721..309476	Azoarcus sp. BH72	4606307
YP_931787.1	CDS	azo0283	NC_008702.1	309473	310132	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no TMHs. no signal peptide; hypothetical protein	complement(309473..310132)	Azoarcus sp. BH72	4606308
YP_931788.1	CDS	azo0284	NC_008702.1	310129	311193	R	Pfam (PF02801): Beta-ketoacyl synthase, C-terminal domain. Pfam (PF00109): Beta-ketoacyl synthase, N-terminal domain.; Function unclear; putative Beta-ketoacyl synthase family protein	complement(310129..311193)	Azoarcus sp. BH72	4606309
YP_931789.1	CDS	azo0285	NC_008702.1	311190	311462	R	Conserved hypothetical acyl carrier protein. Homology to psptO5093 of P. syringae of 44% (trembl|Q87V48). Interpro: Phosphopanteteine-binding (IPR00613). Pfam: Phosphopantetheine attachment site (PF00550) Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. Tigrfam: acyl_carrier: acyl carrier protein. no signal peptide. no TMHs; Conserved hypothetical protein; acyl carrier protein	complement(311190..311462)	Azoarcus sp. BH72	4606310
YP_931790.1	CDS	azo0286	NC_008702.1	311480	312718	R	Similar to TREMBL:Q7NFQ1 (27% identity); TREMBL:Q97E48 (20% identity); TREMBL:Q8FWI9 (21% identity). TMHMM predicting six transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; putative ABC transporter permease	complement(311480..312718)	Azoarcus sp. BH72	4606311
YP_931791.1	CDS	azo0287	NC_008702.1	312733	313155	R	Probable DNA mismatch repair protein mutS. TREMBL:Q92SQ4:42% identity, 55% similarity. InterPro:IPR002716; PIN. Pfam: PF01850; PIN Absence of signal peptide Absence of transmembrane helices L17: ribosomal protein L17; Function unclear; hypothetical protein	complement(312733..313155)	Azoarcus sp. BH72	4606312
YP_931792.1	CDS	azo0288	NC_008702.1	313152	313379	R	no significant homologies; hypothetical protein	complement(313152..313379)	Azoarcus sp. BH72	4606313
YP_931793.1	CDS	azo0289	NC_008702.1	313482	314405	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8R788 (35% identity); TREMBL:Q81S77 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; ABC transporter ATP-binding protein	complement(313482..314405)	Azoarcus sp. BH72	4606314
YP_931794.1	CDS	azo0290	NC_008702.1	314413	315417	R	Conserved hypothetical protein. Homology to Daro03001929 of Dechloromonas aromatica of 68% (gi|53730629|ref|ZP_00348881.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(314413..315417)	Azoarcus sp. BH72	4606315
YP_931795.1	CDS	azo0291	NC_008702.1	315418	315813	R	Conserved hypothetical protein. Homology to Daro03001928 of Dechloromonas aromatica of 59% (gi|41724574|ref|ZP_00151411.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(315418..315813)	Azoarcus sp. BH72	4606316
YP_931796.1	CDS	darB	NC_008702.1	315826	316980	R	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; this condensing enzyme differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase	complement(315826..316980)	Azoarcus sp. BH72	4606317
YP_931797.1	CDS	darA	NC_008702.1	316973	317914	R	Probable dialkylrecorsinol condensing enzyme. Homology to darA of P. aurantiaca of 56% (trembl|Q84H30(SRS)) no domains predicted no signal peptide 1 TMHs; Family membership; dialkylrecorsinol condensing protein	complement(316973..317914)	Azoarcus sp. BH72	4608587
YP_931798.1	CDS	azo0294	NC_008702.1	317928	319742	R	INVOLVED IN CELL WALL BIOSYNTHESIS AND MAY ALSO ACT AS A SENSOR OF EXTERNAL PENICILLINS, TREMBL:Q7UMP8 (30% identity); TREMBL:Q988N4 (27% identity).; Family membership; putative penicillin-binding protein	complement(317928..319742)	Azoarcus sp. BH72	4608586
YP_931799.1	CDS	azo0295	NC_008702.1	320022	320456	D	Conserved hypothetical protein. Homology to CV2374 of C.violaceum of 31% (tremble:Q7NVG9). No domains predicted. No signal peptide or TMH present.; hypothetical protein	320022..320456	Azoarcus sp. BH72	4606318
YP_931800.1	CDS	azo0296	NC_008702.1	320512	321492	R	InterPro:IPR001279- Metallo-beta-lactamase superfamily,glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. TREMBL:Q7WEK1-55% Identity. Pfam-Presence of phosphoribosyltransferase, tissue factor, and GMP reductaseC like domains Signal P predicting signal peptide and TMHMM predicting transmembrane helices. ccoP: cytochrome c oxidase cbb3-type s; High confidence in function and specificity; metallo-beta-lactamase superfamily protein	complement(320512..321492)	Azoarcus sp. BH72	4606319
YP_931801.1	CDS	azo0297	NC_008702.1	321614	321958	R	Conserved hypothetical protein, 66% similarity to TrEMBL; Q6NA86. Signal peptide present. No TMH reported present.; hypothetical protein	complement(321614..321958)	Azoarcus sp. BH72	4606320
YP_931802.1	CDS	paaY	NC_008702.1	321964	322572	R	pathway:carnitine metabolism (conversion of carnitine to gamma-butyrobetaine). TREMBL:Q9F9V3: 71% identity, 83% similarity similarity:belongs to the transferase hexapeptide repeat family Carnitine operon protein caiE. InterPro:IPR001451; Hexapep_transf. Pfam:PF00132; Hexapep InterPro: Bacterial transferase hexapeptide repeat TIGR00094: conserved hypothetical protein; High confidence in function and specificity; phenyl acetic acid degradation protein	complement(321964..322572)	Azoarcus sp. BH72	4606321
YP_931803.1	CDS	paaZ	NC_008702.1	322766	324430	R	Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership; dehydrogenase	complement(322766..324430)	Azoarcus sp. BH72	4609485
YP_931804.1	CDS	paaG1	NC_008702.1	324719	325522	D	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	324719..325522	Azoarcus sp. BH72	4609486
YP_931805.1	CDS	paaH1	NC_008702.1	325526	327073	D	converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase	325526..327073	Azoarcus sp. BH72	4609472
YP_931806.1	CDS	paaI	NC_008702.1	327066	327536	D	Phenylacetic acid aerobic catabolism. Similar to TREMBL:Q9F9V0 (74% identity); SWISSPROT:P76084 (48% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; High confidence in function and specificity; phenylacetic acid degradation protein PaaI	327066..327536	Azoarcus sp. BH72	4609478
YP_931807.1	CDS	paaK	NC_008702.1	327612	328934	D	Phenylacetate-coenzyme A ligase (EC 6.2.1.30) (Phenylacetyl-CoA ligase) (PA-CoA ligase). catalyzes the activation of phenylacetic acid to phenylacetyl-coA; High confidence in function and specificity; phenylacetate--CoA ligase	327612..328934	Azoarcus sp. BH72	4609480
YP_931808.1	CDS	paaA	NC_008702.1	328992	329987	D	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA	328992..329987	Azoarcus sp. BH72	4609483
YP_931809.1	CDS	paaB	NC_008702.1	330089	330376	D	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB	330089..330376	Azoarcus sp. BH72	4609465
YP_931810.1	CDS	paaC	NC_008702.1	330388	331158	D	Probable phenylacetic acid degradation protein PaaC. Homology to paaI of P. putida of 46% (trembl|O84983). Part of a catabolic pathway of phenylacetic acid. These proteins forms part of a dioxygenase complex. Interpro: Phenylacetic acid catabolic (IPR007814) Pfam: Phenylacetic acid catabolic protein (PF05138) no signal peptide no TMHs; High confidence in function and specificity; phenylacetic acid degradation protein PaaC	330388..331158	Azoarcus sp. BH72	4609466
YP_931811.1	CDS	paaD	NC_008702.1	331218	331709	D	Probable pheylacetic acid degradation protein PaaD. Homology to phaH of P. putida of 54% (trembl|Q88HS8) Interpro: Protein of unknown function DUF59 (IPR002744) Pfam: Domain of unknoen function DUF59 (PF01883). Domain of unknown function DUF59;IPR002744; This family includes prokaryotic proteins of unknown function. The family also includes PhaH O84984 from Pseudomonas putida. PhaH forms a complex with PhaF O84982, PhaG O84983 and PhaI O84985,which hydroxylates phenylacetic acid to 2-hydroxyphenylacetic acid. So members of this family may all be components of ring hydroxylating complexes. no signal peptide no TMHs; High confidence in function and specificity; phenylacetic acid degradation protein PaaD	331218..331709	Azoarcus sp. BH72	4609467
YP_931812.1	CDS	paaE	NC_008702.1	331742	332809	D	Probable phenylacetic acid degradation NADH oxidoreductase paaE. Homology to paaE of E. coli of 50% (sprot|PAAE_ECOLI). Probable PART OF A MULTICOMPONENT OXYGENASE involved in aerobic degradation of phenylacetic acid. InterPro: Oxidoreductase FAD and NAD(P)-binding domain(IPR001433); 2Fe-2S Ferredoxin (IPR006057); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity; phenylacetic acid degradation NADH oxidoreductase PaaE	331742..332809	Azoarcus sp. BH72	4609468
YP_931813.1	CDS	paaR	NC_008702.1	332869	333513	D	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	332869..333513	Azoarcus sp. BH72	4609469
YP_931814.1	CDS	paaJ1	NC_008702.1	333560	334762	D	catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase	333560..334762	Azoarcus sp. BH72	4609484
YP_931815.1	CDS	azo0311	NC_008702.1	334888	336033	D	ABC transporter substrate binding proteins count to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q8XU64 (71%) and to sprot|LIVJ_ECOLI (16%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; ABC transporter substrate-binding protein	334888..336033	Azoarcus sp. BH72	4609481
YP_931816.1	CDS	azo0312	NC_008702.1	336157	337194	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W5E8 (62%), to sprot|BRAD_PSEAE (25%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting nine Tmhelix.; Specificity unclear; ABC transporter permease	336157..337194	Azoarcus sp. BH72	4606322
YP_931817.1	CDS	azo0313	NC_008702.1	337260	339053	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (54%) and to trembl|Q8UFI6 (47%). Pfam: ABC transporter Pfam (PF02653): Branched-chain amino acid transport system / permease component Smart : AAA ATPase SignalP reporting Signal peptide. TMHMM reporting nine Tmhelix.; Specificity unclear; ABC transporter ATP-binding protein/permease	337260..339053	Azoarcus sp. BH72	4606323
YP_931818.1	CDS	azo0314	NC_008702.1	339053	339814	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (68%) and to trembl|Q7WCY5 (63%). Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	339053..339814	Azoarcus sp. BH72	4606324
YP_931819.1	CDS	hupB	NC_008702.1	340402	340677	D	DNA-binding protein HU (DNA-binding protein II) (HB). Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it and thus to prevent its denaturation under extreme environmental conditions. InterPro: Bacterial histone-like DNA-binding protein; High confidence in function and specificity; DNA-binding protein HU	340402..340677	Azoarcus sp. BH72	4606325
YP_931820.1	CDS	rhlE1	NC_008702.1	341121	342464	D	ATP-dependent RNA helicase; Family membership; putative ATP-dependent RNA helicase	341121..342464	Azoarcus sp. BH72	4609042
YP_931821.1	CDS	nusB	NC_008702.1	342549	343016	R	Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB	complement(342549..343016)	Azoarcus sp. BH72	4609716
YP_931822.1	CDS	ribH	NC_008702.1	343013	343483	R	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase	complement(343013..343483)	Azoarcus sp. BH72	4609434
YP_931823.1	CDS	ribAB	NC_008702.1	343535	344626	R	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein	complement(343535..344626)	Azoarcus sp. BH72	4609725
YP_931824.1	CDS	ribE	NC_008702.1	344623	345237	R	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha	complement(344623..345237)	Azoarcus sp. BH72	4609721
YP_931825.1	CDS	cutA2	NC_008702.1	345296	347116	R	Putative Protein disulfide-isomerase (EC 5.3.4.1). Homology to dsbD of E. coli of 37% (sprot|DSBD_ECOLI). Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity). Pfam: Cytochrom C biogenesis protein transporter signal peptide probable 8 TMHs; Family membership; putative protein disulfide-isomerase	complement(345296..347116)	Azoarcus sp. BH72	4609723
YP_931826.1	CDS	cutA1	NC_008702.1	347169	347492	R	Periplasmic divalent cation tolerance protein .36% similarity to E.coli CutA1 protein involved in copper tolerance. InterPro:IPR004323; CutA1. Pfam:PF03091; CutA1; 1.; High confidence in function and specificity; divalent cation tolerance protein	complement(347169..347492)	Azoarcus sp. BH72	4608545
YP_931827.1	CDS	naoA	NC_008702.1	347536	348780	R	TREMBL:Q7MBF3: 80% identity, 89% similarity InterPro:IPR004136; 2nprop_dioxygen. IPR003009; FMN_enzyme. Pfam: PF03060; NPD tim: triosephosphate isomerase Non-secretory protein with no signal peptide. TMHMM predicted no transmembrane helices.; High confidence in function and specificity; 2-nitropropane dioxygenase	complement(347536..348780)	Azoarcus sp. BH72	4608544
YP_931828.1	CDS	azo0324	NC_008702.1	348990	349301	D	Conserved hypothetical protein. Homology to GSU0176 of G.sulfurreducens of 42% (tremble:Q74GR9) No domains predicted. No signal peptide or TMH reported present.; hypothetical protein	348990..349301	Azoarcus sp. BH72	4609327
YP_931829.1	CDS	azo0325	NC_008702.1	349421	350749	D	Putative flavocytochrome protein. 48% FAD_binding_6.IPR001433; Oxred_FAD/NAD(P). Pfam:PF00970; FAD_binding_6; 1.PF00175; NAD_binding_1; 1. TMhelix: 6. Siganl peptide: present.; Function unclear; putative flavocytochrome protein	349421..350749	Azoarcus sp. BH72	4606326
YP_931830.1	CDS	azo0326	NC_008702.1	350997	351800	D	conserved hypothetical protein. Homology to cv0811 of C. violaceum of 43% (trembl|Q7NPT0(SRS) no domains predicted no signal peptide no TMHs; hypothetical protein	350997..351800	Azoarcus sp. BH72	4606327
YP_931831.1	CDS	azo0327	NC_008702.1	351835	352428	R	Putative TetR family transcriptional regulator,; Conserved hypothetical protein; TetR family transcriptional regulator	complement(351835..352428)	Azoarcus sp. BH72	4606328
YP_931832.1	CDS	livK1	NC_008702.1	352603	353745	D	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_SALTY (23%) and to trembl|Q8XUX2 (46%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative leucine-specific binding protein	352603..353745	Azoarcus sp. BH72	4606329
YP_931833.1	CDS	azo0329	NC_008702.1	353800	354273	R	Conserved hypothetical protein. Homology to SCO5300 of Streptomyces coelicolor of 46% (tremble:Q9XAE9). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(353800..354273)	Azoarcus sp. BH72	4609153
YP_931834.1	CDS	blaA	NC_008702.1	354344	355339	R	HTH-type transcriptional regulator blaA (Beta-lactamase regulatory protein blaA). Positive regulator of the expression of the gene (blab) for beta-lactamase. Similar to SWISSPROT: sprot|BLAA_PROVU (32% Proteus vulgaris, HTH-type transcriptional regulator BlaA) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; LysR family transcriptional regulator	complement(354344..355339)	Azoarcus sp. BH72	4606330
YP_931835.1	CDS	azo0331	NC_008702.1	355556	356023	D	Conserved hypothetical protein, 41% similarity to TrEMBL;Q88JC7. Has IPR005544 DUF_HHE:PF03794;Domain of Unknown function:This domain normally occurs as tandem repeats and is found in bacteria, yeast and plants. It contains two fully conserved histidines and one glutamate residue. Members of the family include DnrN, NorA and ScdA, which have been implicated in NO response and cell wall physiology. Has no Signal peptide or TMH reported present.; hypothetical protein	355556..356023	Azoarcus sp. BH72	4608398
YP_931836.1	CDS	azo0332	NC_008702.1	356048	357376	R	Hypothetical protein yqhO. This family consists of various patatin glycoproteins from the total soluble protein in potato tubers.Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids SPROT:P54513: 23% identity, 33% similarity SubtiList: BG11703; yqhO. InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin No signal peptide TMHMM predicted 2 transmembrane helices mobB: molybdopterin-guanine dinucleot; Family membership; putative esterase	complement(356048..357376)	Azoarcus sp. BH72	4606331
YP_931837.1	CDS	azo0333	NC_008702.1	357462	358568	D	Hypothetical protein Rv1063c/MT1093/Mb1092c. TREMBL:Q89EP5: 29% identity, 42% similarity InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin 2A0108: nitrate transporter Absence of signal peptide No. of TMH's: 2 (TMHMM predicted).; Family membership; putative esterase	357462..358568	Azoarcus sp. BH72	4606332
YP_931838.1	CDS	azo0334	NC_008702.1	358579	359157	R	Conserved hypothetical secreted protein. Homology to BPP2140 of Bordetella parapertussis 0f 44% (trembl|Q7W8J3(SRS)) No domains predicted. Signal peptide present. No TMH present. 6PTHBS: 6-pyruvoyl tetrahydrobiopterin; Conserved hypothetical protein; hypothetical protein	complement(358579..359157)	Azoarcus sp. BH72	4606333
YP_931839.1	CDS	azo0335	NC_008702.1	359461	360240	D	EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.; Conserved hypothetical protein; EAL-domain-containing protein	359461..360240	Azoarcus sp. BH72	4606334
YP_931840.1	CDS	azo0336	NC_008702.1	360237	361499	D	PAS/PAC/GGDEF-domain containing protein, suggesting involvement into signalling processes. Similarity to SWISSPROT: sprot|YDAM_ECOLI (24% Escherichia coli, hyp. protein) / TREMBL: trembl|Q887F0 (59% Pseudomonas syringae, hyp. protein) Pfam: PF00990 GGDEF domain. This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box.; Conserved hypothetical protein; PAS/PAC/GGDEF-domain-containing protein	360237..361499	Azoarcus sp. BH72	4606335
YP_931841.1	CDS	azo0337	NC_008702.1	361535	362107	R	Probable hypothetical Protein. Extremely weak homology with hits in the PDB. No Motif/Features/TMH/ or Signal peptide present.; hypothetical protein	complement(361535..362107)	Azoarcus sp. BH72	4606336
YP_931842.1	CDS	pstS1	NC_008702.1	362400	363443	D	38% Peri-phosph.IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR00975; 3a0107s03; 1. Signal peptide present.; High confidence in function and specificity; putative phosphate-binding periplasmic protein	362400..363443	Azoarcus sp. BH72	4606337
YP_931843.1	CDS	azo0339	NC_008702.1	363495	363989	R	Conserved hypothetical membrane protein. Homology to an orf of Acinetobacter sp. (strain ADP1) of 43% (tremble:Q6F6W4). no domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(363495..363989)	Azoarcus sp. BH72	4609643
YP_931844.1	CDS	azo0340	NC_008702.1	364232	364546	R	Conserved hypothetical membrane protein. No homology to the data bank No domains predicted No signal peptide 2 TMHs; hypothetical protein	complement(364232..364546)	Azoarcus sp. BH72	4606338
YP_931845.1	CDS	azo0341	NC_008702.1	364615	365061	D	Putative cytochrome c'. Homology to cytochrome c of R. gelatineosus (sprot|CYCP_RHOGE). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. InterPro: Cytochrome c class II (IPR002321) Pfam: Cytochrome C probable signal peptide no TMHs; Function unclear; putative cytochrome c'	364615..365061	Azoarcus sp. BH72	4606339
YP_931846.1	CDS	nhoA	NC_008702.1	365077	365901	R	Belongs to the arylamine n-acetyltransferase family. Arylamine N-acetyltransferase is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Similar to TREMBL:Q98D42 (47% identity); TREMBL:Q8FHI6 (39% identity); SWISSPROT:P77567 (39% identity). InterPro (IPR001447): N-acetyltransferase Pfam (PF00797): N-acetyltransferase.; High confidence in function and specificity; N-hydroxyarylamine O-acetyltransferase	complement(365077..365901)	Azoarcus sp. BH72	4606340
YP_931847.1	CDS	parA2	NC_008702.1	366042	366704	D	Sporulation initiation inhibitor protein soj. INHIBITS THE INITIATION OF SPORULATION SPO0J ANTAGONIZES THIS INHIBITION. SOJ ULTIMATELY INHIBITS THE ACTIVATION (PHOSPHORYLATION) OF SPO0A. IT IS NOT REQUIRED FOR CHROMOSOME PARTITIONING. InterPro: ParA family ATPase; Function unclear; ParA family protein	366042..366704	Azoarcus sp. BH72	4609356
YP_931848.1	CDS	azo0344	NC_008702.1	366705	367574	D	Probable Hypothetical Protein. No domains,features,motifs, or signal peptide present.; hypothetical protein	366705..367574	Azoarcus sp. BH72	4609498
YP_931849.1	CDS	azo0345	NC_008702.1	367763	369865	R	ATP-dependent DNA helicase pcrA (EC 3.6.1.-). InterPro: UvrD/REP helicase; Specificity unclear; ATP-dependent DNA helicase	complement(367763..369865)	Azoarcus sp. BH72	4606341
YP_931850.1	CDS	azo0346	NC_008702.1	369965	371605	D	42% Na_H_porter.IPR004705; NaHantiport_bac.Bacterial Na+/H+ antiporter Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00831; a_cpa1; 1. Signal peptide present TMHelix: 12; High confidence in function and specificity; putative Na+/H+ antiporter	369965..371605	Azoarcus sp. BH72	4606342
YP_931851.1	CDS	azo0347	NC_008702.1	371653	372096	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal P reporting Signal Peptide present. No TMH reported Present.; hypothetical protein	371653..372096	Azoarcus sp. BH72	4606343
YP_931852.1	CDS	azo0348	NC_008702.1	372236	373684	D	Prenyltransferase family protein. InterPro: UbiA prenyltransferase; Specificity unclear; hypothetical protein	372236..373684	Azoarcus sp. BH72	4606344
YP_931853.1	CDS	azo0349	NC_008702.1	373681	374046	D	Putative Small Multi-Drug resistant(SMR)family protein, 30% identical to TrEMBL;Q8XZS2. Has PF00893,Small Multidrug Resistance protein;IPR000390, Smr:This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx.; putative small multi-drug resistant family protein	373681..374046	Azoarcus sp. BH72	4606345
YP_931854.1	CDS	azo0350	NC_008702.1	374102	375397	R	Conserved hypothetical secreted protein. Homology to gll2146 of G. violaceus of 44% (trembl|Q7NIN7(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(374102..375397)	Azoarcus sp. BH72	4606346
YP_931855.1	CDS	nodJ	NC_008702.1	375522	376307	R	Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family.; High confidence in function and specificity; ABC transporter permease NodJ	complement(375522..376307)	Azoarcus sp. BH72	4606347
YP_931856.1	CDS	azo0352	NC_008702.1	376345	376629	R	Conserved hypothetical protein. Homology to mvpT of E. carotovora of 44% (trembl:Q6D393) No domains predicted. No TMHs No signal peptide; hypothetical protein	complement(376345..376629)	Azoarcus sp. BH72	4609391
YP_931857.1	CDS	azo0353	NC_008702.1	376663	376758	R	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide No TMHs; hypothetical protein	complement(376663..376758)	Azoarcus sp. BH72	4606348
YP_931858.1	CDS	azo0354	NC_008702.1	377176	378156	D	Region start changed from 377491 to 377176 (315 bases); putative methylase	377176..378156	Azoarcus sp. BH72	4606349
YP_931859.1	CDS	azo0355	NC_008702.1	378157	379323	R	Conserved hypothetical protein. Homology to lpg1234 of L.pneumophila of 42% (gnl|keqq|lpn:lpg1234(KEGG)). Has PF04471, Restriction endonuclease;IPR007560, Mrr_cat; Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. No TMHs. No signal peptide.; hypothetical protein	complement(378157..379323)	Azoarcus sp. BH72	4606350
YP_931860.1	CDS	vsr	NC_008702.1	379320	379709	R	Putative hypothetical very short patch repair endonuclease. Homology to vrs of E. coli of 29% (sprot|VSR_ECOLI) All proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. Interpro: DNA mismatch endonuclease vsr (IPR004603) Pfam: DNA mismatch endonuclease Vsr Tigrfam: vsr: DNA mismatch endonuclease no signal peptide no TMHs; Family membership; very short patch repair endonuclease	complement(379320..379709)	Azoarcus sp. BH72	4606351
YP_931861.1	CDS	azo0357	NC_008702.1	379781	380920	R	hypothetical protein	complement(379781..380920)	Azoarcus sp. BH72	4610095
YP_931862.1	CDS	azo0358	NC_008702.1	380934	383189	R	Region start changed from 382943 to 383189 (246 bases); putative two-component sensor kinase	complement(380934..383189)	Azoarcus sp. BH72	4606352
YP_931863.1	CDS	azo0359	NC_008702.1	383349	384059	R	Conserved hypothetical membrane protein. Homology to MS2110 of M.succiniciproducens of 40% (gi|52426165|ref|YP_089302.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Family membership; hypothetical protein	complement(383349..384059)	Azoarcus sp. BH72	4606353
YP_931864.1	CDS	nodI	NC_008702.1	384192	385178	R	Nod factor export ATP-binding protein. Part of the ABC transporter complex nodIJ (TC 3.A.1.102.1) involved in the export of LCO (lipo-chitin oligosaccharide) and a modified beta-14-linked N- acetylglucosamine oligosaccharide. Responsible for energy coupling to the transport system, TREMBL:Q7W9D3 (58% identity); SWISSPROT:O52618 (53% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. Pfam (PF00005): ABC transporter. TC (3.A.1.102) The Lipooligosaccharide Exporter (LOSE) Family.; High confidence in function and specificity; ABC transporter ATP-binding protein	complement(384192..385178)	Azoarcus sp. BH72	4606354
YP_931865.1	CDS	azo0361	NC_008702.1	385249	385866	R	Conserved hypothetical glutathione S-transferase. Homology to cv3306 of C. violaceum of 50% (trembl|Q7NSW3). Conjugation of reduced glutathione to a variety of targets. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain. no signal peptide. no TMHs; Conserved hypothetical protein; glutathione S-transferase	complement(385249..385866)	Azoarcus sp. BH72	4609390
YP_931866.1	CDS	azo0362	NC_008702.1	385891	386562	R	Conserved hypothetical protein. Homology to rsc0328 of R. solanacearum of 59% (trembl|Q8Y2K7). Pfam: Prolyl oligopeptidas family no signal peptide no TMHs; hypothetical protein	complement(385891..386562)	Azoarcus sp. BH72	4606355
YP_931867.1	CDS	fer21	NC_008702.1	386572	386892	R	Putative ferredoxin 2fe-2s protein. Homology to fer2 of C. pasteruianum of 35% (sprot|FER2_CLOPA). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide no TMHs; Family membership; putative ferredoxin 2Fe-2S protein	complement(386572..386892)	Azoarcus sp. BH72	4606356
YP_931868.1	CDS	azo0364	NC_008702.1	386915	388000	R	Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors . no signal peptide 10 TMHs; Conserved hypothetical protein; hypothetical protein	complement(386915..388000)	Azoarcus sp. BH72	4608757
YP_931869.1	CDS	azo0365	NC_008702.1	388715	389227	D	Conserved Hypothetical protein, Q82Y48,Rhodanese type protein. Has SMART SM00450 Rhodanese Homology Domain(RHOD)starting at position 47-153aa;Rhodanese, a sulfurtransferase involved in cyanide detoxification (see IPR001307) shares evolutionary relationship with a large family of proteins. No Signal peptide or TMH reported Present.; Family membership; hypothetical protein	388715..389227	Azoarcus sp. BH72	4606357
YP_931870.1	CDS	srpH	NC_008702.1	389292	390254	D	Probable serine O-acetyltransferase plasmid (EC 2.3.1.30) (SAT). Homology to srpH of Synechococcus of 55% (sprot|SRPH_SYNP7) no signal peptide no TMHs; High confidence in function and specificity; serine O-acetyltransferase	389292..390254	Azoarcus sp. BH72	4606358
YP_931871.1	CDS	azo0367	NC_008702.1	390251	390484	D	SgrAlc control protein,; High confidence in function and specificity; SgrAlc control protein	390251..390484	Azoarcus sp. BH72	4609891
YP_931872.1	CDS	mmpI	NC_008702.1	390602	391528	D	Probable immunodominant 35 kDa protein. Homology to mmpI of Mycobacterium avium of 69% (gi|2498566|sp|Q48899|MMP1_MYCAV(SwissProt (ExPASy)). No domains predicted. No signal peptide. No TMHs.,; High confidence in function and specificity; immunodominant 35kDa protein	390602..391528	Azoarcus sp. BH72	4606359
YP_931873.1	CDS	csdB	NC_008702.1	391503	393335	D	Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear; cysteine desulfurase	391503..393335	Azoarcus sp. BH72	4609230
YP_931874.1	CDS	azo0370	NC_008702.1	393595	394170	D	Conserved hypothetical membrane protein. Homology to NE2493 of Nitrosomonas europaea of 67% (trembl|Q82S65(SRS)). Has PF01169, Uncharacterized protein family UPF0016;IPR001727; This family contains integral membrane proteins of unknown function. Most members of the family contain two copies of a region that contains an EXGD motif. No signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	393595..394170	Azoarcus sp. BH72	4608537
YP_931875.1	CDS	azo0371	NC_008702.1	394317	395381	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	394317..395381	Azoarcus sp. BH72	4606360
YP_931876.1	CDS	azo0372	NC_008702.1	395413	395931	R	Entry name SWISSPROT:YHBT_ECOLI Prim. accession # P45474 InterPro IPR003033; SCP2. Pfam PF02036; SCP2; 1. Prediction: Non-secretory protein Signal peptide probability: 0.001 Number of predicted TMHs: 0 Identities = 46/107 (42%); hypothetical protein	complement(395413..395931)	Azoarcus sp. BH72	4606361
YP_931877.1	CDS	azo0373	NC_008702.1	395946	396842	R	Conserved hypothetical peptidase. Homology to Rsp0969 of R. solanacearum of 51% (trembl|Q8XR90). Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership; peptidase	complement(395946..396842)	Azoarcus sp. BH72	4606362
YP_931878.1	CDS	azo0374	NC_008702.1	396857	397870	R	Conserved hypothetical peptidase. Homology to cv4084 of C. violaceum of 64% (trembl|Q7NQQ39. Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership; peptidase	complement(396857..397870)	Azoarcus sp. BH72	4606363
YP_931879.1	CDS	azo0375	NC_008702.1	398061	399524	R	TREMBL:Q8Y273: 59% identity, 72% similarity Osmoregulated proline transporter (Sodium/proline symporter). CATALYZES THE SODIUM-DEPENDENT UPTAKE OF EXTRACELLULAR PROLINE. InterPro: Sodium:solute symporter family InterPro:IPR001734; Na/solut_symport. Pfam:PF00474; SSF; TMHMM predicted transmembrane helices sss: SSS sodium solute transporter sup; Function unclear; sodium/solute symporter transmembrane protein	complement(398061..399524)	Azoarcus sp. BH72	4606364
YP_931880.1	CDS	azo0376	NC_008702.1	399721	401841	R	Conserved hypothetical protein. Homology to ebA3609 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA3609(KEGG)). InterPro: Aminotransferase class-III (IPR005814), Arginase family (IPR00594). Pfam: Aminotransferase class-III,Arginase family. Tigrfam: argD: acetylornithine and succinylornithine aminotransferase, GABAtrnsam:4-aminobutyrate aminotransferase. no signal peptide. no TMHs; hypothetical protein	complement(399721..401841)	Azoarcus sp. BH72	4606365
YP_931881.1	CDS	ubiB	NC_008702.1	401938	403467	R	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB	complement(401938..403467)	Azoarcus sp. BH72	4606366
YP_931882.1	CDS	azo0378	NC_008702.1	403712	405787	R	Putative TonB-dependent receptor. Homology to bpp0186 ao B. parapertussis of 54% (trembl|Q7W206) The TonB protein interacts with outer membrane receptor proteins that carry out high-affinity binding and energy-dependent uptake of specific substrates into the periplasmic space. These substrates are either poorly permeable through the porin channels or are encountered at very low concentrations. In the absence of TonB these receptors bind their substrates but do not carry out active transport. Interpro: TonB-dependent receptor (IPR000531) Pfam: TonB-dependent receptor (PF00593) signal Peptide no TMHs; Family membership; putative TonB-dependent receptor	complement(403712..405787)	Azoarcus sp. BH72	4606367
YP_931883.1	CDS	azo0379	NC_008702.1	405969	406301	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. No TMHs; hypothetical protein	complement(405969..406301)	Azoarcus sp. BH72	4606368
YP_931884.1	CDS	argS	NC_008702.1	406538	408301	D	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase	406538..408301	Azoarcus sp. BH72	4606369
YP_931885.1	CDS	azo0381	NC_008702.1	408318	408902	D	Conserved hypothetical secreted protein. Homology to CV3999 of C.violaceum of 34% (trembl|Q7NQY6(SRS)). Pfam: Sporulation related repeat This 35 residue repeat is found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This repeat might be involved in binding peptidoglycan (Bateman A pers obs). No TMHs. Signal peptide present; Conserved hypothetical protein; hypothetical protein	408318..408902	Azoarcus sp. BH72	4608341
YP_931886.1	CDS	dsbA	NC_008702.1	408982	409629	D	Putative protein disulfide-isomerase. Homology to dsbA of P. flourescens of 34%. Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Tigrfam: redox_disulf_1: redox-active disulfid Pfam: DSBA Oxidoreductase signal peptide no TMHS; Family membership; putative protein disulfide-isomerase	408982..409629	Azoarcus sp. BH72	4606370
YP_931887.1	CDS	azo0383	NC_008702.1	409658	410446	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8Y2Q1 (42% identity); SWISSPROT:P25970 (34% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short chain dehydrogenase	409658..410446	Azoarcus sp. BH72	4608653
YP_931888.1	CDS	azo0384	NC_008702.1	410530	410949	D	Hypothetical protein. No Good homologs in the DB matching the length of the protein. No Significant domains,features,motifs present.; hypothetical protein	410530..410949	Azoarcus sp. BH72	4606371
YP_931889.1	CDS	azo0385	NC_008702.1	410991	412268	D	Hypothetical membrane protein. Homology to vng2292h of Halobacterium sp. of 25% (trembl|Q9HN16(SRS). no domains predicted .no signal peptide. 10 TMHs; hypothetical protein	410991..412268	Azoarcus sp. BH72	4606372
YP_931890.1	CDS	azo0386	NC_008702.1	412265	413521	D	Hypothetical membrane protein. No good homology to a protein of similar length in the data bank. no domains predicted no singal peptide 9 TMHs; hypothetical protein	412265..413521	Azoarcus sp. BH72	4606373
YP_931891.1	CDS	azo0387	NC_008702.1	413530	414396	D	Conserved hypothetical periplasmic binding proten. Homology to rs03250 of R. solanacearum of 53% (trembl|Q8Y2Q2). Interpro: Periplasmic binding protein (IPR002491). Pfam: Periplasmic binding protein (PF01497). This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport. no signal peptide. no TMHs.; Conserved hypothetical protein; periplasmic binding protein	413530..414396	Azoarcus sp. BH72	4606374
YP_931892.1	CDS	azo0388	NC_008702.1	414428	414877	R	Conserved hypothetical protein. Homology to ebA3626 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA3626(KEGG)). InterPro: Protein of unknown function DUF132 InterPro:IPR002850; DUF132. IPR002716; PIN. IPR006596; PINc. Pfam:PF01850; PIN; SMART:SM00670; PINc; TIGRFAMs:TIGR00305; DUF132 TIGR00305: conserved hypothetical protein T. Non-secretory protein with very low signalpeptide probability (0.003) (Signal P predicted). Absence of transmembrane helices; hypothetical protein	complement(414428..414877)	Azoarcus sp. BH72	4606375
YP_931893.1	CDS	phbC1	NC_008702.1	414946	416775	R	Function:-Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name TREMBL:Q8KXD5 Prim. accession # Q8KXD5 Identities = 354/607 (58%) InterPro IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Number of predicted TMHs: 0; High confidence in function and specificity; poly-beta-hydroxybutyrate synthase	complement(414946..416775)	Azoarcus sp. BH72	4606376
YP_931894.1	CDS	azo0390	NC_008702.1	416816	417844	R	conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices.; Specificity unclear; hypothetical protein	complement(416816..417844)	Azoarcus sp. BH72	4609541
YP_931895.1	CDS	azo0391	NC_008702.1	417987	418430	D	Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif.; Family membership; MerR family transcriptional regulator	417987..418430	Azoarcus sp. BH72	4606377
YP_931896.1	CDS	azo0392	NC_008702.1	418560	419027	D	Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050.; Function unclear; hypothetical protein	418560..419027	Azoarcus sp. BH72	4606378
YP_931897.1	CDS	fadAx	NC_008702.1	419104	420315	D	Probable acyl-CoA thiolase. Homology to fadAx of P. putida of 67% (gnl|keqq|ppu:PP2215(KEGG)). IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC:2.3.1.9) and 3-ketoacyl-CoA thiolase (EC:2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid -oxidation. Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of acetoacetyl-CoA and involved in biosynthetic pathways such as poly -hydroxybutyrate synthesis or steroid biogenesis.Prediction: Non-secretory protein Signal peptide probability: 0.002 Number of predicted TMHs: 0; Specificity unclear; acyl-CoA thiolase	419104..420315	Azoarcus sp. BH72	4606379
YP_931898.1	CDS	fadfX	NC_008702.1	420508	421641	D	Activity:- Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q9AHX9 Prim. accession # Q9AHX9 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 244/375 (65%) Number of predicted TMHs: 0; Family membership; acyl-CoA dehydrogenase	420508..421641	Azoarcus sp. BH72	4608719
YP_931899.1	CDS	azo0395	NC_008702.1	421777	422394	D	Similar to TREMBL:Q8Y2R2 (42% identity); TREMBL:Q7WEK4 (30% identity); TREMBL:Q88IW7 (27% identity). Pfam (HCCA_isomerase): 2-hydroxychromene-2-carboxylate isomerase.; Family membership; 2-hydroxychromene-2-carboxylate isomerase	421777..422394	Azoarcus sp. BH72	4608727
YP_931900.1	CDS	azo0396	NC_008702.1	422445	422642	D	Conserved hypothetical protein. Homology to cc1308 of C. crescentus of 35% (trembl|Q9A8P5). Pfam:DUF1289 This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. no signal peptide no TMHs; hypothetical protein	422445..422642	Azoarcus sp. BH72	4606380
YP_931901.1	CDS	azo0397	NC_008702.1	422639	422824	D	Hypothetical protein, 54% identity to TrEMBl;Q8YGQ7. Has PF06945, Protein of unknown function (DUF1289);IPR010710;This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown.; hypothetical protein	422639..422824	Azoarcus sp. BH72	4606381
YP_931902.1	CDS	azo0398	NC_008702.1	422821	423738	D	Probable Hypothetical protein ycbL. TREMBL:Q8Y2S7-43% identity,57% similarity. TIGRFAM:2A0115-Benzoate transport proteins belong to this group. Benzyl alcohol,benzaldehyde, benzoate, and anthranilate are metabolized via catechol, cis,cis-muconate, and the beta-ketoadipate pathway in some bacteria InterPro: Metallo-beta-lactamase superfamily Pfam:Metallo Beta lactamase superfamily, Phage lysozyme TMHMM predicted transmembrane heleces ftsZ: cell division protein FtsZ; Function unclear; putative beta lactamase	422821..423738	Azoarcus sp. BH72	4606382
YP_931903.1	CDS	azo0399	NC_008702.1	423811	424689	D	Hypothetical UPF0042 protein YPO3586/Y0158. SWISPROT:Q82TN5: 6i% identity, 78% similarity This is a family of putative P-loop ATPases. Many of the proteins in this family are hypothetical and kinase activity has been proposed for some family members InterPro:IPR005337; UPF0042. Pfam: PF03668; ATP_bind_2 No Signal peptide (Signal P predicted) No transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Function unclear; hypothetical protein	423811..424689	Azoarcus sp. BH72	4606383
YP_931904.1	CDS	azo0400	NC_008702.1	424686	425081	D	Conserved hypothetical membrane protein. Homology to TP1032 of Treponema pallidum of 32% (sprot|YA32_TREPA(SRS)). Has PF07009(IPR010739):Protein of unknown function (DUF1312);This family consists of several bacterial proteins of around 120 residues in length. The function of this family is unknown. No singal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	424686..425081	Azoarcus sp. BH72	4606384
YP_931905.1	CDS	azo0401	NC_008702.1	425062	425604	D	Heptaprenyl diphosphate synthase component I, 23% identity (45% similarity) to TrEMBL;Q896H9. Has PF07456,Heptaprenyl diphosphate synthase component I;IPR010898,Hpre_diP_synt_I: This family contains component I of bacterial heptaprenyl diphosphate synthase (approximately 170 residues long). This is one of the two dissociable subunits that form the enzyme, both of which are required for the catalysis of the biosynthesis of the side chain of menaquinone-7.; heptaprenyl diphosphate synthase component I	425062..425604	Azoarcus sp. BH72	4606385
YP_931906.1	CDS	cheB1	NC_008702.1	425612	426709	R	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase	complement(425612..426709)	Azoarcus sp. BH72	4606386
YP_931907.1	CDS	cheR1	NC_008702.1	426736	427560	R	Probable chemotaxis protein methyltransferase,CheR_Metranf. IPR001601; Methyltransf. IPR000051; SAM_bind. Pfam: PF01739; CheR. PF03705; CheR_N. SMART: SM00138; MeTrc. Chemotaxis protein methyltransferase (EC 2.1.1.80). METHYLATION OF THE MEMBRANE-BOUND METHYL-ACCEPTING CHEMOTAXIS PROTEINS (MCP) TO FORM GAMMA-GLUTAMYL METHYL ESTER RESIDUES IN MCP.Annotation derived from meta auto annotator.; High confidence in function and specificity; chemotaxis protein methyltransferase	complement(426736..427560)	Azoarcus sp. BH72	4608467
YP_931908.1	CDS	cheD	NC_008702.1	427566	428156	R	Conserved hypothetical chemotaxis protein CheD. Homology to cheD of S. oneidensis of 41% (trembl|Q8EF62). Interpro: CheD (IPR005659). Pfam: CheD (PF03975). This chemotaxis protein stimulates methylation of MCP proteins. no signal peptide. no TMHs; Conserved hypothetical protein; chemotaxis protein CheD	complement(427566..428156)	Azoarcus sp. BH72	4608470
YP_931909.1	CDS	cheW1	NC_008702.1	428223	428765	R	Probable positive regulator of CheA protein activity, CheW. Pfam: PF01584; CheW. SMART: SM00260; CheW. Chemotaxis protein cheW.Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges chea to the mcps (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to cheY and cheB.; High confidence in function and specificity; positive regulator of CheA protein activity	complement(428223..428765)	Azoarcus sp. BH72	4608469
YP_931910.1	CDS	azo0406	NC_008702.1	428787	431225	R	Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Family membership; putative methyl-accepting chemotaxis protein	complement(428787..431225)	Azoarcus sp. BH72	4608474
YP_931911.1	CDS	azo0407	NC_008702.1	431253	433700	R	Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices.; Family membership; putative methyl-accepting chemotaxis protein	complement(431253..433700)	Azoarcus sp. BH72	4606387
YP_931912.1	CDS	cheA1	NC_008702.1	433738	435933	R	Putative chemotaxis histidine kinase protein,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY.; High confidence in function and specificity; putative chemotaxis protein histidine kinase	complement(433738..435933)	Azoarcus sp. BH72	4606388
YP_931913.1	CDS	azo0409	NC_008702.1	435947	436255	R	Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; Function unclear; STAS domain-containing protein	complement(435947..436255)	Azoarcus sp. BH72	4608464
YP_931914.1	CDS	azo0410	NC_008702.1	436258	437526	R	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Function unclear; putative methyl-accepting chemotaxis protein	complement(436258..437526)	Azoarcus sp. BH72	4606389
YP_931915.1	CDS	cheY1	NC_008702.1	437534	437899	R	Probable chemotaxis response regulator,; High confidence in function and specificity; chemotaxis response regulator	complement(437534..437899)	Azoarcus sp. BH72	4606390
YP_931916.1	CDS	azo0412	NC_008702.1	438349	439440	R	Conserved hypothetical membrane protein. Homology to rsc0739 of R. solanacearum of 52% (trembl|Q8Y1F1). Pfam: DUF395 This family includes YeeE and YedE from E. coli. These proteins are integral membrane proteins of unknown function. Many of these proteins contain two homologous regions that are represented by this family. This region contains several conserved glycines and an invariant cysteine that is probably an important functional residue. signal peptide 8 TMHs; Conserved hypothetical protein; hypothetical protein	complement(438349..439440)	Azoarcus sp. BH72	4610008
YP_931917.1	CDS	exsB	NC_008702.1	439455	440141	R	Conserved hypothetical ExsB protein. Homology to exsB of P. syringae of 70% (trembl|Q87Y44). This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In Rhizobium meliloti, a species in which the exo genes make succinoglycan, a symbiotically important exopolysaccharide, exsB is located nearby and affects succinoglycan levels, probably through polar effects on exsA expression or the same polycistronic mRNA. Interpro: ExsB (IPR004479). Pfam: ExsB (PF06508). Tigrfam: TIGR00364: exsB protein. Has signal peptide present. No TMHs; Family membership; ExsB protein	complement(439455..440141)	Azoarcus sp. BH72	4606391
YP_931918.1	CDS	azo0414	NC_008702.1	440170	440832	R	Conserved hypothetical radical activating enzyme. Homology to xac3139 of X. axonopodis of 60% (trembl|Q8PHW0). InterPro: Radical activating enzymes (IPR001989) Pfam: Radical activating enzyme no signal peptide no TMHs; Family membership; putative radical activating enzyme	complement(440170..440832)	Azoarcus sp. BH72	4608707
YP_931919.1	CDS	azo0415	NC_008702.1	440843	441562	R	Conserved hypothetical secreted protein. Homology to RS05116 of R.solanacearum of 38% (trembl|Q8Y1F3(SRS)) No domains predicted. No TMHs Has signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(440843..441562)	Azoarcus sp. BH72	4606392
YP_931920.1	CDS	pal	NC_008702.1	441562	442080	R	Putative peptidoglycan-associated lipoprotein. Homology to pal of E. coli of 36% (sprot|PAL_ECOLI). Thought to play a role in bacterial envelope integrity. Very strongly associated with the peptidoglycan. Pfam: ompA family signal peptide no TMHs; Family membership; putative peptidoglycan-associated lipoprotein	complement(441562..442080)	Azoarcus sp. BH72	4606393
YP_931921.1	CDS	tolB	NC_008702.1	442120	443403	R	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB	complement(442120..443403)	Azoarcus sp. BH72	4609491
YP_931922.1	CDS	tolA	NC_008702.1	443450	444292	R	Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(443450..444292)	Azoarcus sp. BH72	4609958
YP_931923.1	CDS	tolR	NC_008702.1	444289	444702	R	Putative translocation protein TolR. Holomology to tolR of P. aeruginosa of 30% (sprot|TOLR_PSEAE) Involved in eth TonB-independent uptake of proteins. no signal peptide probable 1 TMH; Family membership; putative translocation protein TolR	complement(444289..444702)	Azoarcus sp. BH72	4609957
YP_931924.1	CDS	tolQ	NC_008702.1	444721	445395	R	Translocation protein TolQ. Homology to tolQ of R. solanacearum of 52%. Involved in the tonB-independent uptake of proteins. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHs; High confidence in function and specificity; translocation protein TolQ	complement(444721..445395)	Azoarcus sp. BH72	4609961
YP_931925.1	CDS	azo0421	NC_008702.1	445392	445859	R	Conserved hypothetical thioesterase. Homology to bb4233 of B. bronchiseptica of 41% (trembl|Q7WFN8). Tigrfam: TIGR00051: conserved hypothetical protein .Pfam: 4-hydroxybenzol-CoA thioesterase (PF0361). Interpro: 4-hydroxybenzol-CoA thioesterase (IPR006684); thioesterase superfamily (IPR006683) This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. no signal peptide. no TMHs; Family membership; putative thioesterase	complement(445392..445859)	Azoarcus sp. BH72	4609960
YP_931926.1	CDS	azo0422	NC_008702.1	445887	447230	D	SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP predicted). No transmembrane helices present (TMHMM predicted); Function unclear; hypothetical protein	445887..447230	Azoarcus sp. BH72	4606394
YP_931927.1	CDS	hslV	NC_008702.1	447262	447798	D	heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit	447262..447798	Azoarcus sp. BH72	4606395
YP_931928.1	CDS	hslU	NC_008702.1	447833	449164	D	heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU	447833..449164	Azoarcus sp. BH72	4609037
YP_931929.1	CDS	mdcF1	NC_008702.1	449266	450138	D	Putative malonate transporter. subcellular location:integral membrane protein (potential). similarity: belongs to the auxin efflux carrier (tc 2.a.69) family. SPROT:P56948:24% identity, 41% similarity. InterPro: IPR004776; Auxin_eff. Pfam:PF03547; Auxin_eff 2a69: Auxin Efflux Carrier; Specificity unclear; putative malonate transporter	449266..450138	Azoarcus sp. BH72	4609036
YP_931930.1	CDS	azo0426	NC_008702.1	450142	452085	R	GGDEF/PAS-domain containing protein; diguanylate cyclase	complement(450142..452085)	Azoarcus sp. BH72	4609201
YP_931931.1	CDS	hslR	NC_008702.1	452338	452742	R	Heat shock protein 15 homolog (HSP15). INVOLVED IN THE RECYCLING OF FREE 50S RIBOSOMAL SUBUNITS THAT STILL CARRY A NASCENT CHAIN. BINDS RNA MORE SPECIFICALLY THAN DNA. BINDS WITH VERY HIGH AFFINITY TO THE FREE 50S RIBOSOMAL SUBUNIT. DOES NOT BIND IT WHEN IT IS PART OF THE 70S RIBOSOME; Conserved hypothetical protein; heat shock protein	complement(452338..452742)	Azoarcus sp. BH72	4606396
YP_931932.1	CDS	cysN/C	NC_008702.1	452792	454072	R	55% Adenylylsulfate kinase (EC 2.7.1.25) (APS kinase) (ATP adenosine-5-phosphosulfate 3-phosphotransferase)], from Pseudomonas aeruginosa. FUNCTION:ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity (By similarity). FUNCTION:APS kinase catalyzes the synthesis of activated sulfate (By similarity). CATALYTIC ACTIVITY:ATP + sulfate = diphosphate + adenylylsulfate. CATALYTIC ACTIVITY:ATP + adenylylsulfate=ADP +3'-phosphoadenylylsulfate. PATHWAY: Sulfate activation; cysteine biosynthesis reductive branch; first step. PATHWAY:Sulfate activation; cysteine biosynthesis reductive branch; second step. SUBUNIT:Heterodimer composed of cysD, the smaller subunit,and cysN (By similarity). SIMILARITY:In the N-terminal section; belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily. SIMILARITY:In the C-terminal section; Belongs to the APS kinase family. SWISSPROT:CYSN_PSEAE:O50274. InterPro:IPR002891;APS_kinase.IPR004161;EFTU_D2.IPR009001; Elong_init_C.IPR000795; ProtSyn_GTPbind.IPR005225; Small_GTP.IPR009000; Translat_factor. Pfam:PF01583; APS_kinase; 1.PF00009; GTP_EFTU; 1.PF03144; GTP_EFTU_D2;1. TIGRFAMs:TIGR00455; apsK; 1.TIGR00231; small_GTP; 1.; High confidence in function and specificity; putative sulfate adenylyltransferase subunit 1/adenylylsulfate kinase	complement(452792..454072)	Azoarcus sp. BH72	4609035
YP_931933.1	CDS	cysD	NC_008702.1	454492	455406	R	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2	complement(454492..455406)	Azoarcus sp. BH72	4608562
YP_931934.1	CDS	cysH	NC_008702.1	455534	456304	R	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase	complement(455534..456304)	Azoarcus sp. BH72	4608556
YP_931935.1	CDS	azo0431	NC_008702.1	456301	456831	R	Conserved hypothetical protein. Homology to PA1837 of P.aeruginosa of 50% (tremble:Q9I2Q8). Has PF06073,Bacterial protein of unknown function (DUF934);IPR008318 UCP030820: This family consists of several bacterial proteins of unknown function. One of the members of this family Q8YEW3 is thought to be an oxidoreductase. No signal peptide. No TMHs; hypothetical protein	complement(456301..456831)	Azoarcus sp. BH72	4608558
YP_931936.1	CDS	cysI	NC_008702.1	456824	458506	R	49% Fd-NiR.IPR011255; NiR_SiRalpha_1/3.IPR006067; Nir_Sir_4Fe4S.IPR005117; NiR_SiR_beta_fer. Pfam:PF01077; NIR_SIR; 2.PF03460; NIR_SIR_ferr; 2.; High confidence in function and specificity; putative sulfite reductase	complement(456824..458506)	Azoarcus sp. BH72	4606397
YP_931937.1	CDS	azo0433	NC_008702.1	458559	459338	R	Conserved hypothetical membrane protein. Homology to bll1489 of B. japonicum of 58% (trembl|Q89UC8(SRS)) InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 Presence of 8 transmembrane helices (TMHMM predicted) probable transmembrane protein of unknown function) no signal peptide; Conserved hypothetical protein; hypothetical protein	complement(458559..459338)	Azoarcus sp. BH72	4608559
YP_931938.1	CDS	cysB	NC_008702.1	459444	460385	D	HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator). this protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of l-cysteine from inorganic sulfate. the inducer for cysb is n-acetylserine. cysb inhibits its own transcription.; High confidence in function and specificity; transcriptional regulator CysB-like protein	459444..460385	Azoarcus sp. BH72	4606398
YP_931939.1	CDS	azo0435	NC_008702.1	460530	461414	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal peptide present. No TMHs; hypothetical protein	460530..461414	Azoarcus sp. BH72	4608555
YP_931940.1	CDS	azo0436	NC_008702.1	461424	462398	R	L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase).; Family membership; L-asparaginase II	complement(461424..462398)	Azoarcus sp. BH72	4606399
YP_931941.1	CDS	azo0437	NC_008702.1	462427	463827	R	Region start changed from 463959 to 463827 (-132 bases); aspartate ammonia-lyase	complement(462427..463827)	Azoarcus sp. BH72	4606400
YP_931942.1	CDS	ansB2	NC_008702.1	463964	465061	R	L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase).; High confidence in function and specificity; periplasmic L-asparaginase II	complement(463964..465061)	Azoarcus sp. BH72	4606401
YP_931943.1	CDS	glnQ1	NC_008702.1	465187	465915	R	Glutamine transport ATP-binding protein glnQ. Homology with glnQ of B. stearothermophilus of 56% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs; High confidence in function and specificity; glutamine transport ATP-binding protein	complement(465187..465915)	Azoarcus sp. BH72	4608321
YP_931944.1	CDS	glnM	NC_008702.1	465947	466627	R	Putative glutamine transport permease. Homology to glnM of B. subtilis of 30% (TREMBL:O34671) Probably part of the binding-protein-dependent transport system of amino acids. Probably responsible for the translocation of the substrate across the membrane InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component no signal peptide probable 5 TMHs; Family membership; putative glutamine transport permease	complement(465947..466627)	Azoarcus sp. BH72	4608902
YP_931945.1	CDS	glnP	NC_008702.1	466629	467366	R	Glutamate/aspartate transport system permease gltJ. Homology to glnP of B. subtilis of 23% (CAA93320). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component HTH-motif probable 4 TMHs no signal peptide; Family membership; putative glutamine transport permease	complement(466629..467366)	Azoarcus sp. BH72	4608900
YP_931946.1	CDS	glnH	NC_008702.1	467763	468662	R	Putative glutamine-binding protein. Homology to glnH of B. stearothermophilus of 28% (sprot|GLNH_BACST). Involved in glutamine-transport system. Interacts with the glutamine-transport system glnPQM. Pfam: Bacterial extracellular solute binding protein no TMHs signal peptide; Family membership; putative glutamine-binding protein	complement(467763..468662)	Azoarcus sp. BH72	4608901
YP_931947.1	CDS	azo0443	NC_008702.1	468959	470002	D	Conserved Hypothetical protein(Metallo-beta-lactamase superfamily). Has PF00753, Metallo-beta-lactamase superfamily; IPR001279, Blactmase-like;These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.; Family membership; beta-lactamase	468959..470002	Azoarcus sp. BH72	4608898
YP_931948.1	CDS	lig2	NC_008702.1	469999	471642	D	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; ATP-dependent DNA ligase	469999..471642	Azoarcus sp. BH72	4606402
YP_931949.1	CDS	azo0445	NC_008702.1	471695	474442	D	Putative ATP-dependent helicase MTH1802. TREMBL:Q88NV1: 57% identity, 66% similarity InterPro:IPR001410; DEAD/DEAH box helicase IPR001650; Helicase_C. Pfam: PF00270; DEAD; 1. PF00271; Helicase_C; 1. SMART: SM00487; DEXDc; 1. SM00490: HELICc livcs: branched-chain amino acid trans Non secretory protein with low probablity of cleavage site (0.167): Signal P predicted. No transmembrane helices (TMHMM predicted); High confidence in function and specificity; ATP-dependent helicase	471695..474442	Azoarcus sp. BH72	4609138
YP_931950.1	CDS	azo0446	NC_008702.1	474445	475113	D	Probable Hypothetical protein MJ0037. Members of this uncharacterized family share a motif approximating DXH(X25)GDXXD(X25)GNHD as found in several phosphoesterases, including the nucleases SbcD and Mre11. SbcD is a subunit of the SbcCD nuclease of Escherichia coli that can cleave DNA hairpins to unblock stalled DNA replication. All members of this family are archaeal TREMBL:Q88NV2: 46% identity, 59% similarity InterPro:IPR004843; M-ppestrase. Pfam: PF00149; Metallophos; No transmembrane helices TIGR00024: conserved hypothetical prot; Function unclear; hypothetical protein	474445..475113	Azoarcus sp. BH72	4606403
YP_931951.1	CDS	dctD1	NC_008702.1	475122	476456	R	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity; transcriptional regulator	complement(475122..476456)	Azoarcus sp. BH72	4606404
YP_931952.1	CDS	dctB1	NC_008702.1	476453	478414	R	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity; sensor histidine kinase	complement(476453..478414)	Azoarcus sp. BH72	4608595
YP_931953.1	CDS	kefB	NC_008702.1	478380	480146	R	Glutathione-regulated potassium-efflux system protein kefB,(K+/H+ antiporter).Transport system that facilitates potassium-efflux possibly by potassium-proton antiport. 32% K_eff.IPR006153; Na_H_porter.IPR006036;TrkA_Kuptake. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA-N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:12. Belongs to the monovalent cation:proton antiporter 2 (cpa2) transporter (TC 2.A.37) family. KefB subfamily.; High confidence in function and specificity; putative glutathione-regulated potassium-efflux system protein	complement(478380..480146)	Azoarcus sp. BH72	4608593
YP_931954.1	CDS	azo0450	NC_008702.1	480291	482036	D	PAS/PAC/GGDEF-domain containing protein,implicating involvement into signalling processes. Similarity to TREMBL: trembl|Q98JA6 (30% Rhizobium loti,hypothetical protein mlr2027) InterPro: IPR000160 GGDEF. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. Pfam: PF00990 GGDEF. SMART: SM00086 PAC. SM00091 PAS. TIGRFAM: TIGR00254 GGDEF. TIGR00229 sensory_box.; PAS/PAC/GGDEF-domain-containing protein	480291..482036	Azoarcus sp. BH72	4609105
YP_931955.1	CDS	azo0451	NC_008702.1	482053	482613	R	Hypothetical secreted protein. No homology with hits in the Database. No domains predicted. Signal peptide present. No TMHs; hypothetical protein	complement(482053..482613)	Azoarcus sp. BH72	4606405
YP_931956.1	CDS	trxB1	NC_008702.1	482675	483571	R	Putative thioredoxin reductase. Homology to trxB of S. coelicolor of 25% (sprot|TRXB_STRCO). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership; putative thioredoxin-disulfide reductase	complement(482675..483571)	Azoarcus sp. BH72	4606406
YP_931957.1	CDS	atm1	NC_008702.1	483653	485464	R	Probable composite transport ATP-binding permease protein. Homology to amt1 of S. cereviciae of 48% (sprot|ATM1_YEAST). COULD BE INVOLVED IN THE TRANSPORT OF yet unknow substrates (probable HEME) FROM THE MITOCHONDRIA TO THE CYTOSOL. InterPro: ABC transporter transmembrane region (IPR001140), ATP/GTP-binding site motif A (P loop) (IPR001687), ABC transporter (IPR003439),AAA_ATPase sperfamily (IPR003593) Pfam: ATP transporterABC transporter transmembrane region no signal peptide probable 6 TMHs; Specificity unclear; composite transport ATP-binding permase	complement(483653..485464)	Azoarcus sp. BH72	4610041
YP_931958.1	CDS	azo0454	NC_008702.1	485487	486122	R	Conserved hypothetical threonine efflux protein. Homology to rsc0148 of R. solanaxearum of 52% (trembl|Q8Y2B8). InterPro: Lysine exporter protein (LYSE/YGGA) (IPR001123) Pfam: LysE type translocator Tigrfam: 2A76: Homoserine/Threonine efflux protein signal peptide Probable 6 TMHs; Family membership; putative threonine efflux protein	complement(485487..486122)	Azoarcus sp. BH72	4608364
YP_931959.1	CDS	azo0455	NC_008702.1	486445	487725	D	This family of proteins contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomonas denitrificans [1]. TREMBL:Q8YJP6: 40% identity, 54% similarity. Pfam:PF02492; Cobalmine synthesis protein; pfkB family carbohydrate kinase; FAD binding domain. TIGRFAM:proC: pyrroline 5 carboxylate reductase. mobB: molybdopterin-guanine dinucleotide; Family membership; putative cobalmin snthesis protein	486445..487725	Azoarcus sp. BH72	4606407
YP_931960.1	CDS	azo0456	NC_008702.1	487845	488045	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. no TMHs; hypothetical protein	487845..488045	Azoarcus sp. BH72	4606408
YP_931961.1	CDS	ragA	NC_008702.1	488198	488884	D	Response regulator,; High confidence in function and specificity; two-component response regulator	488198..488884	Azoarcus sp. BH72	4606409
YP_931962.1	CDS	ragB	NC_008702.1	488874	490262	D	Putative sensor kinase,; High confidence in function and specificity; putative two component sensor kinase	488874..490262	Azoarcus sp. BH72	4609693
YP_931963.1	CDS	amtD	NC_008702.1	490448	491650	D	Putative ammonium transporter MJ1343. A number of evolutionarily-related proteins have been found to be involved in the transport of ammonium ions across membranes.Represent a family of high affinity ammonium transporters. These proteins are highly hydrophobic and seem to contain from 10 to 12 transmembrane domain. TREMBL:Q88L29: 73% identity, 84% similarity InterPro: Ammonium transporter family InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp; 1. PROSITE: PS01219; AMMONIUM_TRANSP amt: ammonium transporter Non secretory protein with signal peptide probability of 0.174 (SignalP predicted) TMHMM predicted 11 TMH's; High confidence in function and specificity; ammonia permease	490448..491650	Azoarcus sp. BH72	4609694
YP_931964.1	CDS	dnr	NC_008702.1	491666	492280	R	Putative Dnr-like transcriptional activator. Similar to SWISSPROT: sprot|FIXK_RHIME (28% Rhizobium meliloti, FixK) InterPro: IPR000595 cNMP_binding. IPR001808 HTH_Crp. Pfam: PF00027 cNMP_binding. HTH reporting nucleic acid binding motif.; Family membership; putative Dnr-like transcriptional activator	complement(491666..492280)	Azoarcus sp. BH72	4608317
YP_931965.1	CDS	azo0461	NC_008702.1	492369	492854	D	Hypthetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has signal peptide.; hypothetical protein	492369..492854	Azoarcus sp. BH72	4608641
YP_931966.1	CDS	azo0462	NC_008702.1	492897	495704	R	Conserved hypothetical secreted protein. Homology to an orf of Trichodesmium erythraeum of 45% (gi|48892210|ref|ZP_00325608.1|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(492897..495704)	Azoarcus sp. BH72	4606410
YP_931967.1	CDS	fadE	NC_008702.1	495962	498433	D	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase	495962..498433	Azoarcus sp. BH72	4606411
YP_931968.1	CDS	fadA1	NC_008702.1	498430	499902	D	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase	498430..499902	Azoarcus sp. BH72	4608726
YP_931969.1	CDS	fadB1	NC_008702.1	499899	501935	D	alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1.; Family membership; enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase	499899..501935	Azoarcus sp. BH72	4608717
YP_931970.1	CDS	azo0466	NC_008702.1	501932	502336	D	Conserved hypothetical acyl-CoA thioesterase. Homology to an orf of Azoarcus sp. EbN1 (trembl|Q8G9D6). Pfam: cytosolic long-chain acyl-CoA thioesterase Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. Interpro: Thioesterase superfamily (IPR006683) no signal peptide no. TMHs; Family membership; acyl-CoA thioesterase	501932..502336	Azoarcus sp. BH72	4608720
YP_931971.1	CDS	fadL	NC_008702.1	502438	503721	D	Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) (Outer membrane flp protein). Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel (By similarity). Entry name:- Q8G9D7 Primary accession number:- Q8G9D7 InterPro:- IPR005017; Toluene_X. Pfam:- PF03349; Toluene_X; 1. identity:- 66% Prediction: Signal peptide Signal peptide probability: 1.0 Number of predicted TMHs: 0; High confidence in function and specificity; long-chain fatty acid ABC transporter	502438..503721	Azoarcus sp. BH72	4606412
YP_931972.1	CDS	fadB2	NC_008702.1	503770	506154	D	Short-chain enoyl-CoA hydratase activity . Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership; 3-hydroxyacyl-CoA dehydrogenase	503770..506154	Azoarcus sp. BH72	4608728
YP_931973.1	CDS	fadA2	NC_008702.1	506636	507868	D	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase	506636..507868	Azoarcus sp. BH72	4608721
YP_931974.1	CDS	paaG2	NC_008702.1	507945	508745	D	Function:- COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). CATALYTIC ACTIVITY:-(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name SWISSPROT:PAAG_ECOLI Prim. accession # P77467 InterPro:- IPR001753; EnCoA_hydrtse. Pfam:-PF00378; ECH; 1. Identities = 92/265 (34%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; enoyl-CoA hydratase	507945..508745	Azoarcus sp. BH72	4608718
YP_931975.1	CDS	azo0471	NC_008702.1	508774	509625	R	Conserved hypothetical membrane protein. Homology to cv1508 of C. violaceum of 37% (trembl|Q7NXW8). Pfam: uncharacterized ACR, COG1434. no signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(508774..509625)	Azoarcus sp. BH72	4609473
YP_931976.1	CDS	azo0472	NC_008702.1	509624	510913	D	Probable O-acetylhomoserine aminocarboxypropyltransferase. Homology to cysD of A. nidulans of 54% (sprot|CYSD_EMENI). Transforms O-acetylhomoserine into homocysteine. InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes (IPR000277) Pfam: Cys/Met metabolism PLP-dependent enzymes no signal peptide no TMHs; High confidence in function and specificity; O-acetylhomoserine aminocarboxypropyltransferase	509624..510913	Azoarcus sp. BH72	4606413
YP_931977.1	CDS	azo0473	NC_008702.1	510910	511497	D	Hypothetical membrane protein. No good homology to the data bank. No domains predicted. 1 TMHs No signal peptide present.; hypothetical protein	510910..511497	Azoarcus sp. BH72	4606414
YP_931978.1	CDS	azo0474	NC_008702.1	511494	512357	D	Exported protein with sporulation related repeat. Pfam: Sporulation related repeat. InterPro: Proline-rich region; Function unclear; peptidoglycan-binding protein	511494..512357	Azoarcus sp. BH72	4606415
YP_931979.1	CDS	azo0475	NC_008702.1	512441	512881	D	binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW	512441..512881	Azoarcus sp. BH72	4606416
YP_931980.1	CDS	azo0476	NC_008702.1	512981	513361	D	Conserved hypothetical endoribonuclase L-PSP. Homology to orf1 of A. vineladii of 74% (sprot|YVN1_AZOVI(SRS)) This protein was described initially as an inhibitor of protein synthesis intiation but is now viewed as an endoribonuclease active on single-stranded mRNA. The cleavage of mRNA is responsible for the inhibition of protein synthesis. A role in purine regulation has also been suggested. Tigrfam: Endoribonuclease L-PSP, putative Pfam: Endoribonuclease L-PSP (=YipgF family) no TMHs weak indication for signal peptide; Conserved hypothetical protein; endoribonuclease L-PSP	512981..513361	Azoarcus sp. BH72	4606417
YP_931981.1	CDS	recG	NC_008702.1	513369	515408	D	catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG	513369..515408	Azoarcus sp. BH72	4606418
YP_931982.1	CDS	ubiC	NC_008702.1	515463	516032	D	Chorismate:pyruvate lyase (EC 4.-.-.-). catalytic activity: chorismate = 4-hydroxybenzoate + pyruvate. pathway: ubiquinone biosynthesis; first step.; Specificity unclear; putative chorismate:pyruvate lyase	515463..516032	Azoarcus sp. BH72	4609706
YP_931983.1	CDS	ubiA	NC_008702.1	516019	516882	D	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase	516019..516882	Azoarcus sp. BH72	4610057
YP_931984.1	CDS	azo0480	NC_008702.1	516980	520849	R	Conserved hypothetical irons-sulfur binding oxidase. Homology to cv4235 of C. violaceum of 70% (trembl|Q7NQA5) Pfam: FAD binding domain; FAD linked oxidase, Cterminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership; iron-sulfur binding oxidase	complement(516980..520849)	Azoarcus sp. BH72	4610056
YP_931985.1	CDS	azo0481	NC_008702.1	520972	521325	R	hypothetical protein	complement(520972..521325)	Azoarcus sp. BH72	4606419
YP_931986.1	CDS	azo0482	NC_008702.1	521370	521783	R	Conserved hypothetical membrane protein. Homology to yqaA of Nitrosomonas europaea of 50% (trembl|Q82TH7(SRS)) No domains predicted. Signal peptide present. TMHMM2 reporting presence of 2 TMH's.; Conserved hypothetical protein; hypothetical protein	complement(521370..521783)	Azoarcus sp. BH72	4606420
YP_931987.1	CDS	azo0483	NC_008702.1	521919	522353	D	Conserved hypothetical secreted protein. Homology to PA4874 of P.aeruginosa of 36% (trembl|Q9HUT9(SRS)) No domains predicted. Signal petide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	521919..522353	Azoarcus sp. BH72	4606421
YP_931988.1	CDS	azo0484	NC_008702.1	522433	523299	R	FHA domain containing protein. Best similarity to SWISSPROT: sprot|REPB_AGRRH (9% Agrobacterium rhizogenes,possible replication protein b) Pfam: PF00211 Adenylate and Guanylate cyclase catalytic domain. SMART: SM00240 FHA Forkhead associated domain.; FHA domain-containing protein	complement(522433..523299)	Azoarcus sp. BH72	4606422
YP_931989.1	CDS	azo0485	NC_008702.1	523396	524316	R	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase	complement(523396..524316)	Azoarcus sp. BH72	4606423
YP_931990.1	CDS	azo0486	NC_008702.1	524389	525135	R	Involved in pteridine salvage and antifolate resistance; pteridine reductase	complement(524389..525135)	Azoarcus sp. BH72	4606424
YP_931991.1	CDS	azo0487	NC_008702.1	525247	526419	D	Conserved hypothetical protein. Homology to NE1166 of N.europaea of 49% (tremble:Q82VC8) Has PF02636,Uncharacterized ACR, COG1565;IPR003788 ,DUF185; This family contains several uncharacterised proteins. Q8YI87 has been described as an ATP synthase beta subunit transcription termination factor rho protein. No signal peptide. No TMHs.; hypothetical protein	525247..526419	Azoarcus sp. BH72	4606425
YP_931992.1	CDS	azo0488	NC_008702.1	526459	526677	R	Conserved hypothetical protein. Homology to ebA3372 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA3372(KEGG)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(526459..526677)	Azoarcus sp. BH72	4606426
YP_931993.1	CDS	azo0489	NC_008702.1	526664	526792	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	526664..526792	Azoarcus sp. BH72	4606427
YP_931994.1	CDS	azo0490	NC_008702.1	526887	527693	R	TREMBL:Q8F3A6: 43% identity, 60% similarity Non-heme chloroperoxidase (EC 1.11.1.10) (Chloride peroxidase) (CPO-P) (Chloroperoxidase P). CHLORINATES AND BROMINATES SUITABLE ORGANIC COMPOUNDS. INVOLVED IN THE BIOSYNTHESIS OF THE ANTIBIOTIC PYRROLNITRIN. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR003089: AB_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1; 1 TIGRFAM:dsbE: periplasmic protein thiol:disulf; Family membership; putative acetone-cyanohydrin lyase	complement(526887..527693)	Azoarcus sp. BH72	4606428
YP_931995.1	CDS	isoJ	NC_008702.1	527690	528310	R	Probable glutathione S-transferase. Homology to isoJ of Rhodococcus sp AD45 of 48% (trembl|Q9RBP3). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity; glutathione S-transferase	complement(527690..528310)	Azoarcus sp. BH72	4606429
YP_931996.1	CDS	azo0492	NC_008702.1	528392	528589	D	Conserved hypothetical membrane protein. Homology to BH1226 of Bacillus halodurans of 40% (pir|B83803) no domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	528392..528589	Azoarcus sp. BH72	4609093
YP_931997.1	CDS	cca	NC_008702.1	528605	529843	R	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase	complement(528605..529843)	Azoarcus sp. BH72	4606430
YP_931998.1	CDS	sspA1	NC_008702.1	529843	530487	R	Putative stringent starvation protein A. Homology to sspA of E. coli of 26% (sprot|SSPA_ECOLI). FORMS AN EQUIMOLAR COMPLEX WITH THE RNA POLYMERASE HOLOENZYME (RNAP) BUT NOT WITH THE CORE ENZYME. IT IS SYNTHESIZED PREDOMINANTLY WHEN CELLS ARE EXPOSED TO AMINO ACID STARVATION AT WHICH TIME IT ACCOUNTS FOR OVER 50% OF THE TOTAL PROTEIN SYNTHESIZED. InterPro: Glutathione S-transferase N terminus (IPR001045) Pfam: Glutathione S-transferase, N-terminal domaine no signal peptide no TMHs; Family membership; putative stringent starvation protein A	complement(529843..530487)	Azoarcus sp. BH72	4608441
YP_931999.1	CDS	azo0495	NC_008702.1	530568	531536	R	33%; Specificity unclear; putative NADH dehydrogenase	complement(530568..531536)	Azoarcus sp. BH72	4609895
YP_932000.1	CDS	sltY	NC_008702.1	531552	533480	R	Putative soluble lytic murein transglycosylase. Homology to slt of E. coli of 24% (sprot|SLT_ECOLI). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. InterPro: SLT domain (IPR000189) Pfam: Transglycosylase SLT domain singal peptide no TMHs; High confidence in function and specificity; putative soulbe lytic murein transglycosylase	complement(531552..533480)	Azoarcus sp. BH72	4606431
YP_932001.1	CDS	azo0497	NC_008702.1	533521	534114	D	5-formyltetrahydrofolate cyclo-ligase InterPro: 5-formyltetrahydrofolate cyclo-ligase; Specificity unclear; hypothetical protein	533521..534114	Azoarcus sp. BH72	4609874
YP_932002.1	CDS	azo0498	NC_008702.1	534121	536826	R	GGDEF/PAS/PAC-domain containing protein. Similarity to SWISSPROT: sprot|Y4LL_RHISN (13% Rhizobium sp. (strain NGR234), hypothetical 91.8 kda protein y4ll) / TREMBL: trembl|Q55955 (14% Synechocystis sp. (strain PCC 6803),sll0779) Pfam: PF00990 GGDEF domain. PF00989 PAS. PF00785 PAC. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box. TMHMM reporting 2 transmembrane helices.; diguanylate cyclase	complement(534121..536826)	Azoarcus sp. BH72	4606432
YP_932003.1	CDS	pheC	NC_008702.1	536846	537652	R	Putative cyclohexadienyl dehydratase precursor. Homology to pheC of P. aeruginosa of 36% (sprot|PHEC_PSEAE) FORMS ALTERNATIVE PATHWAY FOR PHENYLALANINE BIOSYNTHESIS. CAN CATALYZE TWO REACTIONS: PREPHENATE DEHYDRATASE AND AROGENATE DEHYDRATASE. MAY HAVE A ROLE IN CHEMOTAXIS OR TRANSPORT. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638), solute-binding protein/glutamate receptor (IPR001311) Pfam: Bacterial extracellular solute-binding proteins signal peptide no TMHs; Function unclear; putative cyclohexadienyl dehydratase	complement(536846..537652)	Azoarcus sp. BH72	4606433
YP_932004.1	CDS	ilvA	NC_008702.1	537808	539328	R	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase	complement(537808..539328)	Azoarcus sp. BH72	4609545
YP_932005.1	CDS	hprK	NC_008702.1	539453	540394	R	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase	complement(539453..540394)	Azoarcus sp. BH72	4609068
YP_932006.1	CDS	ptsN	NC_008702.1	540363	540848	R	Probable nitrogen regulatory IIA protein,; High confidence in function and specificity; protein-Npi-phosphohistidine-sugar phosphotransferase	complement(540363..540848)	Azoarcus sp. BH72	4609026
YP_932007.1	CDS	rpoX	NC_008702.1	540982	541305	R	Probable sigma 54 modulation protein,; High confidence in function and specificity; sigma-54 modulation protein	complement(540982..541305)	Azoarcus sp. BH72	4609651
YP_932008.1	CDS	rpoN1	NC_008702.1	541320	542780	R	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54	complement(541320..542780)	Azoarcus sp. BH72	4609803
YP_932009.1	CDS	yhbG	NC_008702.1	542790	543512	R	Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity; ABC transporter ATPase	complement(542790..543512)	Azoarcus sp. BH72	4609800
YP_932010.1	CDS	recX	NC_008702.1	543499	543948	R	Regulatory protein recX. Modulates recA activity (By similarity). TREMBL: Q7WKM9: 45% identity, 63% similarity InterPro: RecX regulatory protein InterPro; IPR003783; RecX. Pfam: PF02631; RecX PPR: pentatricopeptide repeat domain No transmembrane helices present; Family membership; regulatory protein	complement(543499..543948)	Azoarcus sp. BH72	4610180
YP_932011.1	CDS	recA	NC_008702.1	543971	545005	R	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A	complement(543971..545005)	Azoarcus sp. BH72	4609711
YP_932012.1	CDS	ygaD1	NC_008702.1	545130	545615	R	Hypothetical 17.2 kDa protein 1 in recA 5region. TREMBL:Q9KUH9: 54% identity, 64% similarity CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation [1]. This is a C-terminal region of putative competence-damaged proteins from the cin operon InterPro:IPR008136; CinA_C. Pfam: PF02464; CinA cinA_cterm: competence/damage-inducible p No signal peptide. No transmembrane helices; High confidence in function and specificity; CinA-like protein	complement(545130..545615)	Azoarcus sp. BH72	4609702
YP_932013.1	CDS	azo0509	NC_008702.1	545618	546100	R	Region start changed from 546007 to 546100 (93 bases); putative phosphatidylglycerophosphatase A	complement(545618..546100)	Azoarcus sp. BH72	4610175
YP_932014.1	CDS	thiL	NC_008702.1	546104	547114	R	Thiamine-phosphate kinase. catalytic activity: atp + thiamine phosphate = adp + thiamine diphosphate. pathway: thiamine biosynthesis.; High confidence in function and specificity; thiamine-phosphate kinase	complement(546104..547114)	Azoarcus sp. BH72	4606434
YP_932015.1	CDS	azo0511	NC_008702.1	547249	547530	R	hypothetical protein	complement(547249..547530)	Azoarcus sp. BH72	4609938
YP_932016.1	CDS	rnfE1	NC_008702.1	547551	548285	R	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex subunit RsxE	complement(547551..548285)	Azoarcus sp. BH72	4606435
YP_932017.1	CDS	rnfG1	NC_008702.1	548296	548922	R	Probable electron transport complex protein rnfG. Homolog to rnfG of R. capsulata of 51% (sprot|RNFG_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. signal peptide no TMHs; High confidence in function and specificity; electron transport complex protein RnfG	complement(548296..548922)	Azoarcus sp. BH72	4609748
YP_932018.1	CDS	rnfD1	NC_008702.1	548939	549994	R	Probable electron transport complex protein rnfD. Homology to rnfD of R. capsulatus of 42% (sprot|RNFD_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity). InterPro: NQR2 and RnfD/E related proteins (IPR004338) Pfam: NQR2, RnfD, RnfE family no signal peptide probable 7 TMHs; High confidence in function and specificity; electron transport complex protein RnfD	complement(548939..549994)	Azoarcus sp. BH72	4609750
YP_932019.1	CDS	rnfC1	NC_008702.1	549991	551550	R	Probable electron transport complex protein RnfC. Homology to rnfC of R. capsulatus of 48% (sprot|RNFC_RHOCA) Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Stabilizes rnfB. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); 4Fe-4S ferredoxin, iron-sulfur bidning domain (IPR001450) Pfam: Respiratory-chain NADH dehydrogenase; 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity; electron transport complex protein RnfC	complement(549991..551550)	Azoarcus sp. BH72	4609746
YP_932020.1	CDS	rnfB1	NC_008702.1	551561	552088	R	Probable electron transport complex protein rnfB. Homology to rnfB of R. capsulatus of 48% (sprot|RNFB_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Stabilizes rnfC. Pfam: 4Fe-4S binding domain signal peptide no TMHs; High confidence in function and specificity; electron transport complex protein RnfB	complement(551561..552088)	Azoarcus sp. BH72	4609744
YP_932021.1	CDS	rnfA1	NC_008702.1	552106	552687	R	Probable electron transport complex protein RnfA. Homology to rnfA of R. capsultatus of 66% (RNFA_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Required for stable existence of rnfB and rnfC. InterPro: RnfA-Nqr electron transport subunit (IPR003667) Pfam: Rnf-Nqr subunit, membrane protein no signal peptide 6 TMHs; High confidence in function and specificity; electron transport complex protein RnfA	complement(552106..552687)	Azoarcus sp. BH72	4609742
YP_932022.1	CDS	nifL	NC_008702.1	553036	554607	D	Nitrogen fixation regulatory protein (EC 2.7.3.-). Required for the inhibition of nifA activity in response to oxygen and low level of fixed nitrogen. Similar to SWISSPROT: sprot|NIFL_AZOVI (41% Azotobacter vinelandii,nitrogen fixation regulatory protein (EC 2.7.3.-), NifL) InterPro: IPR003661 His_kinA_N. The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR000014 PAS. PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. IPR000700 PAS-assoc_C. IPR004358 Bact_sens_pr_C. IPR003594 ATPbind_ATPase. Pfam: PF00512 HisKA. PF00989 PAS. PF00785 PAC. TIGRFAM: TIGR00229 PAS domain S-box.; High confidence in function and specificity; nitrogen fixation regulatory protein	553036..554607	Azoarcus sp. BH72	4609740
YP_932023.1	CDS	nifA	NC_008702.1	554604	556157	D	Nif-specific regulatory protein. NIFA A TRANSCRIPTIONAL ACTIVATOR IS REQUIRED FOR ACTIVATION OF MOST NIF OPERONS WHICH ARE DIRECTLY INVOLVED IN NITROGEN FIXATION. NIFA INTERACTS WITH SIGMA-54. InterPro: Sigma-54 factor interaction domain; High confidence in function and specificity; nif-specific regulatory protein	554604..556157	Azoarcus sp. BH72	4609365
YP_932024.1	CDS	azo0520	NC_008702.1	556202	557770	R	Conserved hypothetical secreted protein. Homology to Gmet02000900 of Geobacter metallireducens of 45% (gi|48846570|ref|ZP_00300831.1|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(556202..557770)	Azoarcus sp. BH72	4609357
YP_932025.1	CDS	azo0521	NC_008702.1	557796	558329	R	Hypothetical secreted protein. No Hits in the PDB. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(557796..558329)	Azoarcus sp. BH72	4606436
YP_932026.1	CDS	sodC	NC_008702.1	558326	558853	R	Superoxide dismutase [Cu-Zn]precursor (EC 1.15.1.1), sodC.Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May function against extracytoplasmic toxic oxygen species. 45% SOD_CU_ZN.Copper/Zinc superoxide dismutase. Pfam: PF00080; sodcu; 1. TIGR:CC1579. Signal peptide: present.; High confidence in function and specificity; superoxide dismutase	complement(558326..558853)	Azoarcus sp. BH72	4606437
YP_932027.1	CDS	nifB	NC_008702.1	559180	560676	D	FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR.; High confidence in function and specificity; nitrogen fixation protein	559180..560676	Azoarcus sp. BH72	4609880
YP_932028.1	CDS	azo0524	NC_008702.1	560794	561084	D	Conserved hypothetical ferredoxin. Homology to fdx of P. stuzeri of 57% (trembl|Q93JV5). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4FE-4S binding domain no signal peptide no TMHs; Family membership; ferredoxin	560794..561084	Azoarcus sp. BH72	4609358
YP_932029.1	CDS	azo0525	NC_008702.1	561181	561630	D	Conserved hypothetical protein. Homology to an orf of P. stuzeri of 49% (trembl|Q93JV4). Tigrfam: arsC: arsenate reductase. Pfam: ArsC family (PF03960) no signal peptide. no TMHs; hypothetical protein	561181..561630	Azoarcus sp. BH72	4606438
YP_932030.1	CDS	fprA	NC_008702.1	561627	562916	D	Probable type A flavoprotein fprA . Homology to frpA of R. capsulatus of 58% (sprot|FPRA_RHOCA) Low-potential electron donor to a number of redox enzymes (Potential). InterPro: Metallo-beta-lactamase superfamily (IPR001279); Flavodoxin (IPR001226) Pfam: Metallo-beta-lactamase superfamily; Flavodoxin no singal peptide no TMHs; Family membership; type A flavoprotein	561627..562916	Azoarcus sp. BH72	4606439
YP_932031.1	CDS	fdxC	NC_008702.1	562926	563213	D	Ferredoxin IV (FdIV) (Ferredoxin plant-type). Homology to fdxC of R. capsulatus of 62% (FER4_RHOCA). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. Pfam: 2Fe-2S iron-sulfur clauster binding domain no signal peptide no TMHs; High confidence in function and specificity; ferredoxin IV	562926..563213	Azoarcus sp. BH72	4608826
YP_932032.1	CDS	fdxD	NC_008702.1	563265	563615	D	Ferredoxin V (FdV) (Ferredoxin plant-type). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. InterPro: Ferredoxin; High confidence in function and specificity; ferredoxin V	563265..563615	Azoarcus sp. BH72	4608749
YP_932033.1	CDS	nifQ	NC_008702.1	563680	564255	D	Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership; putative NifQ protein	563680..564255	Azoarcus sp. BH72	4608750
YP_932034.1	CDS	draG1	NC_008702.1	564301	565239	D	Probable ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 44% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase (DraT) transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs; ADP-ribosyl-[dinitrogen reductase] hydrolase	564301..565239	Azoarcus sp. BH72	4609369
YP_932035.1	CDS	azo0531	NC_008702.1	565267	566196	R	Conserved hypothetical secreted protein. Homology to PA2778 of P.aeruginosa of 39% (trembl|Q9I065(SRS)) Has Signal Peptide. No TMH present. Has PF03412:Peptidase C39 family;Lantibiotic and non-lantibiotic bacteriocins are synthesised as precursor peptides containing N-terminal extensions (leader peptides) which are cleaved off during maturation. Most non-lantibiotics and also some lantibiotics have leader peptides of the so-called double-glycine type. These leader peptides share consensus sequences and also a common processing site with two conserved glycine residues in positions -1 and -2. The double- glycine-type leader peptides are unrelated to the N-terminal signal sequences which direct proteins across the cytoplasmic membrane via the sec pathway. Their processing sites are also different from typical signal peptidase cleavage sites, suggesting that a different processing enzyme is involved. Peptide bacteriocins are exported across the cytoplasmic membrane by a dedicated ATP-binding cassette (ABC) transporter. The ABC transporter is the maturation protease and its proteolytic domain resides in the N-terminal part of the protein. This peptidase domain is found in a wide range of ABC transporters, however the presumed catalytic cysteine and histidine are not conserved in all members of this family.; Conserved hypothetical protein; hypothetical protein	complement(565267..566196)	Azoarcus sp. BH72	4608648
YP_932036.1	CDS	azo0532	NC_008702.1	566198	566773	R	Hypothetical membrane protein. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	complement(566198..566773)	Azoarcus sp. BH72	4606440
YP_932037.1	CDS	yjdF	NC_008702.1	566665	567276	R	Hypothetical protein yjdF,44% identity (56% similarity) to TrEMBL;Q8XDT2. SwissProt;P39270. Signal P reporting Signal peptide present. TMHMM2 reporting 3 TMH's present.; hypothetical protein	complement(566665..567276)	Azoarcus sp. BH72	4606441
YP_932038.1	CDS	azo0534	NC_008702.1	567329	568462	R	Hypothetical membrane protein. TREMBL:Q83LX6: 27% identity, 42% similarity. similarity to E.coli ybeT. some,to yeast skt5 and s.pombe spac24b11.10c InterPro; IPR006597; Sel_like. InterPro; IPR001440; TPR. InterPro; IPR008941; TPR-like Pfam:DsbD:Cytochrome C biogenesis protein trans SMART:SM00671; SEL1 Signal peptide present (Signal P) transmembrane helices: 5 (TMHMM predicted).; Function unclear; hypothetical protein	complement(567329..568462)	Azoarcus sp. BH72	4610187
YP_932039.1	CDS	dcrH1	NC_008702.1	568662	569072	R	DcrH: hemerythrin protein,is a transmembrane methyl-accepting protein probably involved in bacterial chemotaxis. 36% Hemerythrin. Hemerythrin family non-heme Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity; putative hemerythrin-like protein	complement(568662..569072)	Azoarcus sp. BH72	4606442
YP_932040.1	CDS	azo0536	NC_008702.1	569083	569934	R	Conserved hypothetical protein. Homology to an orf of Pseudomonas stutzeri of 52% (tremble:Q9EVM9). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(569083..569934)	Azoarcus sp. BH72	4608590
YP_932041.1	CDS	draT	NC_008702.1	570131	570973	R	Putative NAD(+)-dinitrogen-reductase ADP-D-ribosyltransferase (EC 2.4.2.37) (ADP-ribosyltransferase). Homology to draT of R. rubrum of 39% (sprot|DRAT_RHORU(SRS) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: DRAT no signal peptide no TMHs; High confidence in function and specificity; putative NAD(+)-dinitrogen-reductase ADP-D-ribosyltransferase	complement(570131..570973)	Azoarcus sp. BH72	4606443
YP_932042.1	CDS	nifH	NC_008702.1	571215	572108	D	88% NifH.IPR000392; NitrogenaseII. Pfam:PF00142; Fer4_NifH; 1. TIGRFAMs:TIGR02016; BchX; 1.TIGR01287; nifH; 1.; High confidence in function and specificity; putative nitrogenase iron protein	571215..572108	Azoarcus sp. BH72	4608650
YP_932043.1	CDS	nifD	NC_008702.1	572230	573705	D	Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein.; High confidence in function and specificity; nitrogenase molybdenum-iron protein subunit alpha	572230..573705	Azoarcus sp. BH72	4609363
YP_932044.1	CDS	nifK	NC_008702.1	573809	575377	D	Nitrogenase molybdenum-iron protein beta chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein. InterPro: Oxidoreductase nitrogenase component 1 araD: L-ribulose-5-phosphate 4-epimer; High confidence in function and specificity; nitrogenase molybdenum-iron protein subunit beta	573809..575377	Azoarcus sp. BH72	4609359
YP_932045.1	CDS	nifT	NC_008702.1	575484	575708	D	Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present.; High confidence in function and specificity; nitrogen fixation protein NifT	575484..575708	Azoarcus sp. BH72	4609364
YP_932046.1	CDS	fdxN	NC_008702.1	575735	575938	D	Ferredoxin. Pubilication: Egner et al., 2001, J Bacteriol 183, 3752-3760 (trembl|Q9F0V6) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding daimain no signal peptide no TMHs; High confidence in function and specificity; FdxN protein	575735..575938	Azoarcus sp. BH72	4609371
YP_932047.1	CDS	nifY1	NC_008702.1	576021	576743	D	NifY protein. Homology to nifY of Azoarcus sp. BH72 of 99% (gi|11493644|gb|AF200742.1|AF200742(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Function unclear; NifY protein	576021..576743	Azoarcus sp. BH72	4608751
YP_932048.1	CDS	azo0544	NC_008702.1	576740	577012	D	ORF1; Conserved hypothetical protein. Homology to orf1 of Azoarcus sp. BH72 of 100% (gi|11493650|gb|AAG35591.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	576740..577012	Azoarcus sp. BH72	4609376
YP_932049.1	CDS	azo0545	NC_008702.1	577211	578842	D	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Specificity unclear; putative methyl-accepting chemotaxis protein	577211..578842	Azoarcus sp. BH72	4606444
YP_932050.1	CDS	nifM	NC_008702.1	578928	579785	R	Probable peptidylprolyl isomerase. Homology with nifM of A. chroococcum of 43% (sprot|NIFM_AZOCH) REQUIRED FOR THE ACTIVATION AND STABILIZATION OF THE IRON-COMPONENT (NIFH) OF NITROGENASE. PROBABLE PPIASE. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain no signal peptide no TMHs hydrog_prot: hydrogenase maturation pro; High confidence in function and specificity; peptidyl-prolyl isomerase	complement(578928..579785)	Azoarcus sp. BH72	4606445
YP_932051.1	CDS	nifZ	NC_008702.1	579782	580273	R	Nitrogen Fixation protein[nifZ], 51% identity (67% similarity) SwissProt;P14889,66% similarity to SwissProt;P23124. Has PF04319:NifZ domain;(IPR007415)This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal Peptide Or TMH reported Present.; High confidence in function and specificity; nitrogen fixation protein	complement(579782..580273)	Azoarcus sp. BH72	4609366
YP_932052.1	CDS	nifW	NC_008702.1	580294	580614	R	Nitrogenase stabilizing/protective protein nifW,50% identity (68% similarity) to SwissProt;P14888.TrEMBL; Q6US88(60% similarity). Has PF03206:Nitrogen fixation protein NifW;(IPR004893)Nitrogenase is a complex metalloenzyme composed of two proteins designated the Fe-protein and the MoFe-protein. Apart from these two proteins, a number of accessory proteins are essential for the maturation and assembly of nitrogenase. Even though experimental evidence suggests that these accessory proteins are required for nitrogenase activity, the exact roles played by many of these proteins in the functions of nitrogenase are unclear. Using yeast two-hybrid screening it has been shown that NifW can interact with itself as well as NifZ. No Signal Peptide or TMH present.; High confidence in function and specificity; nitrogen fixation protein NifW	complement(580294..580614)	Azoarcus sp. BH72	4609378
YP_932053.1	CDS	azo0549	NC_008702.1	580638	581177	R	Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present.; hypothetical protein	complement(580638..581177)	Azoarcus sp. BH72	4609374
YP_932054.1	CDS	nifP	NC_008702.1	581177	582025	R	Serine acetyltransferase (EC 2.3.1.30). Homology to nifP of A. chrooccum of 58% (pir|D43706). PROBABLE SERINE ACETYLTRANSFERASE REQUIRED FOR OPTIMIZING THE EXPRESSION OF NITROGENASE ACTIVITY. NIFP MAY BE REQUIRED TO BOOST RATES OF SYNTHESIS OR INTRACELLULAR CONCENTRATIONS OF CYSTEINE OR METHIONINE. InterPro: Bacterial transferase hexapeptide repeat (IPR001451) no signal peptide no TMHs; High confidence in function and specificity; serine O-acetyltransferase	complement(581177..582025)	Azoarcus sp. BH72	4606446
YP_932055.1	CDS	nifV	NC_008702.1	582028	583218	R	Homocitrate synthase is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into homocitrate. Similar to sprot|NIFV_AZOVI (51%) and to sprot|NIV1_ANASP (42%). Pfam (PF00682): HMG-CoA Lyase-like family InterPro (PS00815): Alpha-isopropylmalate and homocitrate synthase; High confidence in function and specificity; homocitrate synthase	complement(582028..583218)	Azoarcus sp. BH72	4609368
YP_932056.1	CDS	nifS	NC_008702.1	583307	584530	R	Cysteine desulfurase(Nitrogenase metalloclusters biosynthesis protein nifS). Homology to nifS of A. chroococcum of 71% (sprot|NIFS_AZOCH) CATALYZES THE REMOVAL OF ELEMENTAL SULFUR ATOMS FROM CYSTEINE TO PRODUCE ALANINE. SEEMS TO PARTICIPATE IN THE BIOSYNTHESIS OF THE NITROGENASE METALLOCLUSTERS BY PROVIDING THE INORGANIC SULFUR REQUIRED FOR THE FE-S CORE FORMATION. Pfam: aminotransferase class-V no signal peptide no TMHs; High confidence in function and specificity; cysteine desulfurase	complement(583307..584530)	Azoarcus sp. BH72	4609373
YP_932057.1	CDS	nifU	NC_008702.1	584713	585603	R	Probable nitrogen fixation protein NifU. Homology to nifU of A. vinelandii of 67% (sprot|NIFU_AZOVI). INVOLVED IN THE FORMATION OR REPAIR OF [FE-S] CLUSTERS PRESENT IN IRON-SULFUR PROTEINS. Pfam: NifU-like N-terminal domain, NifU-like domain no signal peptide no TMHs; High confidence in function and specificity; nitrogen fixation protein NifU	complement(584713..585603)	Azoarcus sp. BH72	4609370
YP_932058.1	CDS	hesB	NC_008702.1	585625	585948	R	HesB/yadR/yfhF family protein, 45% identity to TrEMBL;Q9KJL2,Q6HRJ0. SwissProt;P37026(41% identity) Has PF01521, HesB-like domain;IPR000361, HesB_yadR_yfhF;This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation.; High confidence in function and specificity; HesB/yadR/yfhF family protein	complement(585625..585948)	Azoarcus sp. BH72	4609372
YP_932059.1	CDS	azo0555	NC_008702.1	586209	586601	R	Conserved hypothetical protein. Homology to Daro03002610 of Dechloromonas aromatica of 39% (gi|41724013|ref|ZP_00150903.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(586209..586601)	Azoarcus sp. BH72	4608991
YP_932060.1	CDS	fdxB	NC_008702.1	586611	586898	R	Probable ferredoxin. Homology to fdxB of R. capsulatus of 45% (sprot|FER3_RHOCA) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership; ferredoxin	complement(586611..586898)	Azoarcus sp. BH72	4606447
YP_932061.1	CDS	azo0557	NC_008702.1	587039	587254	R	Conserved hypothetical protein Shows similarity to hypothetical 7.7 kDa protein in fixX 3'region (ORF1) of Azorhizobium caulinodans. TIGR00162: conserved hypothetical protein; hypothetical protein	complement(587039..587254)	Azoarcus sp. BH72	4608748
YP_932062.1	CDS	azo0558	NC_008702.1	587265	587750	R	Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present.; Family membership; hypothetical protein	complement(587265..587750)	Azoarcus sp. BH72	4606448
YP_932063.1	CDS	azo0559	NC_008702.1	587769	588176	R	Hypothetical sigma-E factor regulatory protein,best similarity to SWISSPROT: sprot|Y850_HAEIN (Haemophilus influenzae, hypothetical protein hi0850) / sprot|RSEC_ECOLI (23% Escherichia coli, sigma-e factor regulatory protein RseC). TMHMM reporting 2 transmembrane helices.; sigma-E factor regulatory protein	complement(587769..588176)	Azoarcus sp. BH72	4606449
YP_932064.1	CDS	nifX	NC_008702.1	588173	588700	R	Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Conserved hypothetical protein; NifX protein	complement(588173..588700)	Azoarcus sp. BH72	4606450
YP_932065.1	CDS	nifN	NC_008702.1	588618	590012	R	functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe; nitrogenase molybdenum-cofactor biosynthesis protein NifN	complement(588618..590012)	Azoarcus sp. BH72	4609375
YP_932066.1	CDS	nifE	NC_008702.1	590023	591525	R	Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. Homology to nifE of A. vielandii of 70% (sprot|NIFE_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; nitrogenase iron-molybdenum cofactor biosynthesis protein NifE	complement(590023..591525)	Azoarcus sp. BH72	4609367
YP_932067.1	CDS	azo0563	NC_008702.1	591714	592715	R	Probale Hypothetical protein. Very Weak homology spanning the entire length of protein in the data base. No Significant domains,Features,TMH's or Signal Peptide present.; Function unclear; hypothetical protein	complement(591714..592715)	Azoarcus sp. BH72	4609360
YP_932068.1	CDS	azo0564	NC_008702.1	592764	593639	R	Conserved hypothetical protein. Has PF05484:LRV protein FeS4 cluster(IPR008665);This Iron sulphur cluster is found at the N-terminus of some proteins containing LRV repeats. Has 6,(IPR004830) PF01816:Leucine rich repeat variant;The function of this repeat is unknown. It has an unusual structure of two helices. One is an alpha helix,the other is the much rarer 3-10 helix.; Function unclear; hypothetical protein	complement(592764..593639)	Azoarcus sp. BH72	4606451
YP_932069.1	CDS	morA	NC_008702.1	593892	597104	D	GGDEF/EAL/PAS/PAC/GAF-domain containing protein; diguanylate cyclase	593892..597104	Azoarcus sp. BH72	4606452
YP_932070.1	CDS	azo0566	NC_008702.1	597165	597449	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	597165..597449	Azoarcus sp. BH72	4609260
YP_932071.1	CDS	azo0567	NC_008702.1	597475	598143	R	Similar to TREMBL:Q82SF8 (45% identity); TREMBL:Q7P0W9 (43% identity); TREMBL:Q8XV73 (40% identity).; hypothetical protein	complement(597475..598143)	Azoarcus sp. BH72	4606453
YP_932072.1	CDS	vsrA	NC_008702.1	598310	599704	D	Putative sensory box histidine kinase,; High confidence in function and specificity; putative sensory box histidine kinase	598310..599704	Azoarcus sp. BH72	4606454
YP_932073.1	CDS	vsrD1	NC_008702.1	599710	600345	R	DNA-binding response regulator,; High confidence in function and specificity; DNA-binding response regulator	complement(599710..600345)	Azoarcus sp. BH72	4610096
YP_932074.1	CDS	azo0570	NC_008702.1	600348	601409	R	Similar to TREMBL:Q89KB0 (34% identity); TREMBL:Q8XXG5 (34% identity).; hypothetical protein	complement(600348..601409)	Azoarcus sp. BH72	4610098
YP_932075.1	CDS	ruvC	NC_008702.1	601871	602422	R	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase	complement(601871..602422)	Azoarcus sp. BH72	4610009
YP_932076.1	CDS	ybjQ	NC_008702.1	602457	602777	R	Conserved hypothetical protein, ybjQ, 65% identity to SwissProt;P75819. SwiisProt;Q8XGV2(66% identity). TrEMBL;Q83LS2( 65% identity) Has PF01906, Domain of unknown function DUF74;IPR002765; Members of this protein family have no known function. The domain is about 100 amino acids long and found in prokaryotes.; High confidence in function and specificity; hypothetical protein	complement(602457..602777)	Azoarcus sp. BH72	4609837
YP_932077.1	CDS	azo0573	NC_008702.1	602808	603686	R	Conserved hypothetical membrane protein. Hamology to PA3358 of P. aeruginosa of 56% InterPro: Integral membrane protein DUF6 Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHs; Conserved hypothetical protein; hypothetical protein	complement(602808..603686)	Azoarcus sp. BH72	4610151
YP_932078.1	CDS	yebC	NC_008702.1	603781	604506	R	Conserved hypothetical protein,yebC,48% identity (63% similarity) to SwissProt;Q8FGR1,P24237,Q8XFD4. TrEMBL;Q9S4S9. Has PF01709, Domain of unknown function DUF28;IPR002876; This domain is found in bacterial and yeast proteins it compromises the entire length or central region of most of the proteins in the family, all of which are hypothetical with no known function. The average length of this domain is approximately 230 amino acids long.; High confidence in function and specificity; hypothetical protein	complement(603781..604506)	Azoarcus sp. BH72	4606456
YP_932079.1	CDS	azo0575	NC_008702.1	604637	605281	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide Present.; hypothetical protein	604637..605281	Azoarcus sp. BH72	4610169
YP_932080.1	CDS	azo0576	NC_008702.1	605320	606831	D	Conserved hypothetical protein. Homology to yjgR of E. coli of 66% (sprot|YJGR_ECOLI). no signal peptide no TMHs; Family membership; hypothetical protein	605320..606831	Azoarcus sp. BH72	4606457
YP_932081.1	CDS	gstR2	NC_008702.1	606869	607759	R	Probable transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	complement(606869..607759)	Azoarcus sp. BH72	4606458
YP_932082.1	CDS	emrY	NC_008702.1	607889	609352	D	Multidrug resistance protein B homolog. TRANSLOCASE THAT CONFERS RESISTANCE TO SUBSTANCES OF HIGH HYDROPHOBICITY (BY SIMILARITY). Presence of signal peptide and 14 transmembrane helices. Presence of DUF domains,CbiM, and bacterial cytochrome ubiquinol oxidase like domains efflux_EmrB: drug resistance transport; High confidence in function and specificity; multidrug resistence transmembrane protein	607889..609352	Azoarcus sp. BH72	4608960
YP_932083.1	CDS	azo0579	NC_008702.1	609429	610385	D	Conserved hypothetical membrane protein. Homology to RSc2187 of R. solanacerarum of 44%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter Pfam: Intergral membrane protein DUF6 no signal peptide probable 6 TMHs; Conserved hypothetical protein; hypothetical protein	609429..610385	Azoarcus sp. BH72	4608667
YP_932084.1	CDS	azo0580	NC_008702.1	610477	612138	D	Putative methyl-accepting chemotaxis transducer,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices. Methyl-accepting chemotaxis serine transducer. CHEMOTACTIC-SIGNAL TRANSDUCERS RESPOND TO CHANGES IN THE CONCENTRATION OF ATTRACTANTS AND REPELLENTS IN THE ENVIRONMENT TRANSDUCE A SIGNAL FROM THE OUTSIDE TO THE INSIDE OF THE CELL AND FACILITATE SENSORY ADAPTATION THROUGH THE VARIATION OF THE LEVEL OF METHYLATION. ATTRACTANTS INCREASE THE LEVEL OF METHYLATION WHILE REPELLENTS DECREASE THE LEVEL OF METHYLATION THE METHYL GROUPS ARE ADDED BY THE METHYLTRANSFERASE CHER AND REMOVED BY THE METHYLESTERASE CHEB. recN: DNA repair protein RecN; Specificity unclear; putative methyl-accepting chemotaxis transducer	610477..612138	Azoarcus sp. BH72	4606459
YP_932085.1	CDS	araJ	NC_008702.1	612146	613330	R	May be involved in either the transport or processing of arabinose polymers.Belongs to the major facilitator superfamily. 36% MFS.IPR005828; Sub_transporter. TMhelix:12.; High confidence in function and specificity; putative transmembrane efflux protein	complement(612146..613330)	Azoarcus sp. BH72	4606460
YP_932086.1	CDS	azo0582	NC_008702.1	613443	614654	R	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 25% MFS.IPR005828; Sub_transporter.IPR005829; Sug_transporter.InterPro: General substrate transporters Pfam:PF00083; sugar_tr; 1. TMHelix: 12; Specificity unclear; major facilitator superfamily permease	complement(613443..614654)	Azoarcus sp. BH72	4608330
YP_932087.1	CDS	lysR	NC_008702.1	614751	615716	D	Putative transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	614751..615716	Azoarcus sp. BH72	4606461
YP_932088.1	CDS	metF	NC_008702.1	615741	616574	R	510-methylenetetrahydrofolate reductase InterPro: Methylenetetrahydrofolate reductase fadh2: 510-methylenetetrahydrofolate reductase; High confidence in function and specificity; 5,10-methylenetetrahydrofolate reductase	complement(615741..616574)	Azoarcus sp. BH72	4609187
YP_932089.1	CDS	tlyA	NC_008702.1	616561	617238	R	Probable hemolysin.46% identity to TrEMBL;Q7NQ39. Has PF01728, FtsJ-like methyltransferase; IPR002877,RrmJFtsJ_mtfrase; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesised that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.; High confidence in function and specificity; hypothetical protein	complement(616561..617238)	Azoarcus sp. BH72	4609208
YP_932090.1	CDS	azo0586	NC_008702.1	617454	617696	R	Hypothetical protein. Weak Homology with hits in the Database. No domains, repeats, motifs or features could be predicted above threshold value.; hypothetical protein	complement(617454..617696)	Azoarcus sp. BH72	4609952
YP_932091.1	CDS	acyH	NC_008702.1	617790	619199	R	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase	complement(617790..619199)	Azoarcus sp. BH72	4606462
YP_932092.1	CDS	azo0588	NC_008702.1	619475	620047	D	Conserved hypothetical secreted protein. Homology to PA0776 of Pseudomonas aeruginosa of 30% (trembl|Q9I5G2(SRS)) No domains predicted Signal Peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	619475..620047	Azoarcus sp. BH72	4608276
YP_932093.1	CDS	metK	NC_008702.1	620087	621253	R	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase	complement(620087..621253)	Azoarcus sp. BH72	4606463
YP_932094.1	CDS	htrB	NC_008702.1	621534	622355	D	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase	621534..622355	Azoarcus sp. BH72	4609210
YP_932095.1	CDS	msbBa	NC_008702.1	622384	623160	D	Putative Lipid A biosynthesis acyltransferase Homology to msbB of of E. coli of 27% (AAA24181). Homology only with the N-terminus. no signal peptide. 1 TMH. Tigrfam: lipid_A_htrB, lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase. Pfam: Lip_A_acyltrans,Bacterial lipid A biosynthesis acyltransferase.; Family membership; putative lipid A biosynthesis acyltransferase,truncated	622384..623160	Azoarcus sp. BH72	4609041
YP_932096.1	CDS	msbBb	NC_008702.1	623157	623261	D	Putative Lipid A biosynthesis acyltransferase Homology to.msbB of of E. coli of 27% (AAA24181). Homology only with the N-terminus. no signal peptide. 1 TMH. Tigrfam: lipid_A_htrB, lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase. Pfam: Lip_A_acyltrans,Bacterial lipid A biosynthesis acyltransferase.; Function unclear; putative lipid A biosynthesis acyltransferase,truncated	623157..623261	Azoarcus sp. BH72	4609277
YP_932097.1	CDS	azo0593	NC_008702.1	623255	623521	R	Conserved hypothetical membrane protein. Homology to Daro03000819 of Dechloromonas aromatica of 32% (gi|46140899|ref|ZP_00152594.2|(NBCI ENTREZ)). No domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(623255..623521)	Azoarcus sp. BH72	4609278
YP_932098.1	CDS	dapF	NC_008702.1	623683	624516	D	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase	623683..624516	Azoarcus sp. BH72	4606464
YP_932099.1	CDS	azo0595	NC_008702.1	624557	625210	D	Conserved hypothetical protein. Coils2 Program reporting presence of 1 Coiled-Coil. Has SMART;SM00065,GAF domain;This domain is present in phytochromes and cGMP-specific phosphodiesterases. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyses the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. A phytochrome is a regulatory photoreceptor which exists in 2 forms that are reversibly interconvertible by light, the PR form that absorbs maximally in the red region of the spectrum, and the PFR form that absorbs maximally in the far-red region. This domain is also found in NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.; Specificity unclear; 3',5'-cyclic-nucleotide phosphodiesterase	624557..625210	Azoarcus sp. BH72	4608585
YP_932100.1	CDS	xerC	NC_008702.1	625290	626201	D	Tyrosine recombinase xerC. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or psi) sites. In the complex xerC specifically exchanges the top DNA strands (By similarity).; High confidence in function and specificity; site-specific recombinase	625290..626201	Azoarcus sp. BH72	4606465
YP_932101.1	CDS	azo0597	NC_008702.1	626345	626848	D	Conserved hypothetical protein. Homology to ebA3954 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA3954(KEGG)). No domains predictied. No signal peptide. No TMHs. helix-turn-helix present.; hypothetical protein	626345..626848	Azoarcus sp. BH72	4610127
YP_932102.1	CDS	azo0598	NC_008702.1	626914	628101	D	Hypothetical protein yccW TREMBL:Q8Y3C9: 52% identity, 62% similarity. InterPro; IPR002478; PUA. InterPro; IPR000051; SAM_bind. Pfam:Met_1:Met-10+ like-protein SMART; SM00359 TIGR00095: conserved hypothetical protein No transmembrane helices; High confidence in function and specificity; SAM dependent methyl transferase	626914..628101	Azoarcus sp. BH72	4606466
YP_932103.1	CDS	azo0599	NC_008702.1	628098	628448	R	Conserved hypothetical membrane protein. Homology to ebA3957 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA3957(KEGG)). No domains predicted. signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(628098..628448)	Azoarcus sp. BH72	4606467
YP_932104.1	CDS	azo0600	NC_008702.1	628448	628666	R	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	complement(628448..628666)	Azoarcus sp. BH72	4606468
YP_932105.1	CDS	ruvB	NC_008702.1	628671	629729	R	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB	complement(628671..629729)	Azoarcus sp. BH72	4606469
YP_932106.1	CDS	ruvA	NC_008702.1	629785	630384	R	plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA	complement(629785..630384)	Azoarcus sp. BH72	4609836
YP_932107.1	CDS	azo0603	NC_008702.1	630563	631267	D	Conserved hypothetical membrane protein. Homology to BP3397 of B. pertussis of 41% (bpe:BP3397(KEGG)). Tigrfam: azlC: azlC protein (azlC). 6 TMHs no signal peptide; Conserved hypothetical protein; hypothetical protein	630563..631267	Azoarcus sp. BH72	4609835
YP_932108.1	CDS	azo0604	NC_008702.1	631264	631590	D	Conserved hypothetical membrane protein. Homology to RS04896 of Ralstonia solanacearum o 43% (trembl|Q8Y1W8) Has PF06063, Domain of unknown function (DUF931);IPR010337;Family of transmembrane proteins with undetermined function. singal peptide. 2 THMs; Conserved hypothetical protein; hypothetical protein	631264..631590	Azoarcus sp. BH72	4606470
YP_932109.1	CDS	azo0605	NC_008702.1	631597	631851	R	Hypothetical protein. Homology to Daro03002672 of Dechloromonas aromatica of 51% (gi|41723577|ref|ZP_00150487.1|(NBCI ENTREZ)). Has PF04023, FeoA domain;IPR007167; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese. no signal peptide. no TMHs; hypothetical protein	complement(631597..631851)	Azoarcus sp. BH72	4606471
YP_932110.1	CDS	feoB	NC_008702.1	631860	633851	R	Ferrous iron transport protein B, FeoB.Probable GTP-driven transporter of ferrous ion.Invovled in iron II uptake. 29% FeoB.IPR005289; GTP-bindding_dom.IPR005225; Small_GTP. Pfam:PF02421; FeoB; 1.TIGRFAMs TIGR00437; feoB; 1.TIGR00650; MG442; 1. TIGR00231; small_GTP; 1. TMHelix:12 Siganl pepetide present.; High confidence in function and specificity; putative ferrous iron transport protein B	complement(631860..633851)	Azoarcus sp. BH72	4606472
YP_932111.1	CDS	azo0607	NC_008702.1	634049	636247	D	Outer membrane TonB-dependent, hydroxamate-type ferrisiderophore receptor. Probably involved in iron transport. 30% TONB_C.IPR000531; TonB_receptor.IPR010105; TonB_siderophor. InterPro: TonB-dependent receptor protein Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide present.; High confidence in function and specificity; putative TonB-dependent receptor	634049..636247	Azoarcus sp. BH72	4608756
YP_932112.1	CDS	ybiX	NC_008702.1	636324	637007	D	Putative PKHD-type hydroxylase, 69% Identity(82% simialrity) to SwissProt;P59727,Q8FJM69, (48% identity) Has SMART;SM00702, P4Hc,Prolyl 4-hydroxylase alpha subunit homologues: IPR006620; Pro_4_hyd_alph; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. Has PF03171,2OG-Fe(II) oxygenase superfamily;IPR005123;This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases,isopenicillin synthases and AlkB.; High confidence in function and specificity; putative hydroxylase	636324..637007	Azoarcus sp. BH72	4606473
YP_932113.1	CDS	gox	NC_008702.1	637000	638121	D	Probable (S)-2-hydroxy-acid oxidase. Homology to gox of S. oleracea (spinach) of 42% (sprot|GOX_SPIOL). CATALYTIC ACTIVITY: (S)-2-hydroxy-acid + O(2) = 2-oxo acid + H(2)O(2). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009) Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs guaA_Cterm: GMP synthase C-terminal d; Family membership; (S)-2-hydroxy-acid oxidase	637000..638121	Azoarcus sp. BH72	4610150
YP_932114.1	CDS	oprM2	NC_008702.1	638132	639553	R	Putative outer membrane efflux protein. Homology to orpM in P. aeruginosa of 36%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Interpro: Outer membran efflux protein Pfam: Outer membran efflux protein signal peptide no TMHs; Family membership; putative outer membrane efflux protein	complement(638132..639553)	Azoarcus sp. BH72	4608931
YP_932115.1	CDS	macB	NC_008702.1	639568	641538	R	Putative efflux transporter for macrolide antibiotics, TREMBL:Q92NU9 (57% identity); TREMBL:Q884D4 (49% identity). Pfam (PF00005): ABC transporter. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122): The Macrolide Exporter Family.; Specificity unclear; ABC transporter ATP-binding protein/permease	complement(639568..641538)	Azoarcus sp. BH72	4609454
YP_932116.1	CDS	macA	NC_008702.1	641535	642686	R	Macrolide-specific efflux protein macA precursor. Efflux transporter for macrolide antibiotics (By similarity). Membrane Fusion Protein (MFP) family.; High confidence in function and specificity; periplasmic protein of efflux system	complement(641535..642686)	Azoarcus sp. BH72	4609191
YP_932117.1	CDS	exbD3	NC_008702.1	642997	643413	R	Probable fiopolymer transport protein ExbD. Homology to exbD1 of X. campestris of 43%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; High confidence in function and specificity; biopolymer transport protein ExbD	complement(642997..643413)	Azoarcus sp. BH72	4609190
YP_932118.1	CDS	exbB2	NC_008702.1	643413	644174	R	Probable biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 50% ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide no TMHs; Family membership; biopolymer transport protein ExbB	complement(643413..644174)	Azoarcus sp. BH72	4608702
YP_932119.1	CDS	tonB1	NC_008702.1	644177	644926	R	Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear; putative TonB protein	complement(644177..644926)	Azoarcus sp. BH72	4608697
YP_932120.1	CDS	bfr2	NC_008702.1	645213	645689	R	Bacterioferritin (BFR)(Cytochrome B-1)(Cytochrome B-557).May perform analogous functions in iron detoxification and storage to that of animal ferritins.Key role in iron homeostasis. 71% Bacterioferritin.IPR008331; Ferritin_Dps.IPR009040; Ferritin_like. Pfam:PF00210; ferritin; 1. TIGRFAMs:TIGR00754; bfr; 1.; High confidence in function and specificity; putative bacterioferritin	complement(645213..645689)	Azoarcus sp. BH72	4609962
YP_932121.1	CDS	bfd	NC_008702.1	645686	645928	R	Bacterioferritin-associated ferredoxin. Homology to psto4159 of P. syringae of 33% (trembl|Q87XL9). SEEMS TO ASSOCIATE WITH BFR; COULD BE A GENERAL REDOX AND/OR REGULATORY COMPONENT PARTICIPATING IN THE IRON STORAGE MOBILIZATION FUNCTIONS OF BFR. COULD PARTICIPATE IN THE RELEASE OR THE DELIVERY OF IRON FROM/TO BACTERIOFERRITIN (OR OTHER IRON COMPLEXES). Pfam: BFD-like [2Fe-2S] binding domain no signal peptide no TMHs; Conserved hypothetical protein; bacterioferritin-associated ferredoxin	complement(645686..645928)	Azoarcus sp. BH72	4608387
YP_932122.1	CDS	azo0618	NC_008702.1	645969	646178	R	47% DUF1008. Pfam:PF06228; DUF1008; 1.; High confidence in function and specificity; putative hemin uptake protein	complement(645969..646178)	Azoarcus sp. BH72	4608385
YP_932123.1	CDS	azo0619	NC_008702.1	646348	647070	D	Similar to TREMBL:Q8Y2F3 (57% identity); TREMBL:Q7VVV4 (55% identity); TREMBL:Q9I111 (53% identity). Pfam (FAA_hydrolase): Fumarylacetoacetate (FAA) hydrolase family.; hypothetical protein	646348..647070	Azoarcus sp. BH72	4606474
YP_932124.1	CDS	azo0620	NC_008702.1	647080	647529	R	Conserved hypothetical secreted protein. Homology to an orf of G. sulfurreducens of 34% (tremblnew|AAR35905(SRS)). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(647080..647529)	Azoarcus sp. BH72	4606475
YP_932125.1	CDS	azo0621	NC_008702.1	647516	648724	R	Conserved hypothetical secreted protein. Homology to ebA1833 of Azoarcus sp. EbN1 of 48% (gnl|keqq|eba:ebA1833(KEGG)). No domains predicted. Signal peptide Present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(647516..648724)	Azoarcus sp. BH72	4606476
YP_932126.1	CDS	azo0622	NC_008702.1	648721	651168	R	Conserved hypothetical signaling protein. Homology to ebA1830 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA1830(KEGG)). Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. PF00672 HAMP. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. TMHMM reporting 2 transmembrane helices of which one is in the signal peptide. Signal peptide present.; Conserved hypothetical protein; putative signaling protein	complement(648721..651168)	Azoarcus sp. BH72	4606477
YP_932127.1	CDS	matA	NC_008702.1	651269	652651	R	Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. 40% Malonyl_CoA_deC. Pfam:PF05292; MCD; 1.; High confidence in function and specificity; putative malonyl-CoA decarboxylase	complement(651269..652651)	Azoarcus sp. BH72	4606478
YP_932128.1	CDS	azo0624	NC_008702.1	652780	653454	D	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; PAS/PAC domain-containing protein	652780..653454	Azoarcus sp. BH72	4609195
YP_932129.1	CDS	azo0625	NC_008702.1	653521	653943	D	Hypothetical two-component system response regulator, very low similarity to a part of YehT: SWISSPROT: sprot|YEHT_ECOLI (16% Escherichia coli, YehT) Pfam: PF00072 Response_reg.; two-component system response regulator	653521..653943	Azoarcus sp. BH72	4606479
YP_932130.1	CDS	lgt	NC_008702.1	653963	654760	R	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase	complement(653963..654760)	Azoarcus sp. BH72	4606480
YP_932131.1	CDS	yceH	NC_008702.1	654774	655454	R	Conserved hypothetical protein, 47% identity (59% similarity)to TrEMBL;Q8FIR0.TrEMBL;Q83LI7 Has PF04337,Protein of unknown function, DUF480;IPR007432;This family consists of several proteins of uncharacterised function. Coils2 program reporting presence of Coiled-Coil.; High confidence in function and specificity; hypothetical protein	complement(654774..655454)	Azoarcus sp. BH72	4609135
YP_932132.1	CDS	azo0628	NC_008702.1	655581	657689	D	Putative adenylate/guanylate cyclase,; Conserved hypothetical protein; putative adenylate/guanylate cyclase	655581..657689	Azoarcus sp. BH72	4610157
YP_932133.1	CDS	azo0629	NC_008702.1	657725	658321	R	Conserved hypothetical secreted protein. Homology to Daro03000403 of Dechloromonas aromatica of 37% (gi|46140621|ref|ZP_00152222.2|(NBCI ENTREZ)). InterPro: Bacterial outer membrane protein (IPR006664). Pfam: OmpA family. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(657725..658321)	Azoarcus sp. BH72	4606481
YP_932134.1	CDS	azo0630	NC_008702.1	658318	658761	R	Conserved hypothetical secreted protein. Homology to PJS6w01004783 of Polaromonas sp. JS666 of 45% (gi|54028512|ref|ZP_00360661.1|(NBCI ENTREZ)). No domains predicted. signal peptide. TMH in signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(658318..658761)	Azoarcus sp. BH72	4606482
YP_932135.1	CDS	azo0631	NC_008702.1	658869	661868	D	HD-domain containing protein; HD-domain-containing protein	658869..661868	Azoarcus sp. BH72	4606483
YP_932136.1	CDS	ilvD	NC_008702.1	661937	663787	D	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase	661937..663787	Azoarcus sp. BH72	4606484
YP_932137.1	CDS	azo0633	NC_008702.1	663873	664067	D	Conserved hypothetical protein. Homology to Mflag03001107 of Methylobacillus flagellatus of 42% (gi|53759956|ref|ZP_00350342.1|(NBCI ENTREZ)). No Signal peptide or TMH present. No domains predicted.; hypothetical protein	663873..664067	Azoarcus sp. BH72	4609071
YP_932138.1	CDS	azo0634	NC_008702.1	664076	664372	D	Conserved hypothetical protein. Homology to NE1890 of N.europaea of 35% (tremble:Q82TJ7) Has PF05164, Family of unknown function (DUF710);IPR007838;Family of eubacterial hypothetical proteins. No signal peptid. No TMHs; hypothetical protein	664076..664372	Azoarcus sp. BH72	4606485
YP_932139.1	CDS	azo0635	NC_008702.1	664722	665201	D	Hypothetical protein, 72% identity(81% similarity) to TrEMBL;Q82TJ8. TrEMBL;Q8XWR7(62% identity). Has PF04543, Family of unknown function (DUF589);IPR007628 ;Family of uncharacterised proteins; Function unclear; hypothetical protein	664722..665201	Azoarcus sp. BH72	4606486
YP_932140.1	CDS	azo0636	NC_008702.1	665191	665997	D	Conserved hypothetical membrane protein. TREMBL:Q82TJ9: 43% identity, 59% similarity InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 no signal peptide. 8 TMHs; Conserved hypothetical protein; hypothetical protein	665191..665997	Azoarcus sp. BH72	4606487
YP_932141.1	CDS	azo0637	NC_008702.1	666063	666431	D	Hypothetical protein Extremely poor homology with hits in the DB. NO features/signal Peptide/Domains present.; hypothetical protein	666063..666431	Azoarcus sp. BH72	4606488
YP_932142.1	CDS	azo0638	NC_008702.1	666529	667926	D	Conserved hypothtecial protein. Homology to Avin02002811 of Azotobacter vinelandii of 50% (gi|23103464|ref|ZP_00089946.1|(NBCI ENTREZ)). InterPro: Domain of unknown function DUF224 (IPR004017). no signal peptide. no TMHs; hypothetical protein	666529..667926	Azoarcus sp. BH72	4606489
YP_932143.1	CDS	azo0639	NC_008702.1	668039	668347	D	Hypothetical protein. 22% identity to SwissProt;P45905 No domains, repeats, motifs or features present.; hypothetical protein	668039..668347	Azoarcus sp. BH72	4606490
YP_932144.1	CDS	mntC1	NC_008702.1	668355	669284	R	Part of the ABC transporter complex mntABC involved in manganese uptake. 41% Similar to the putative periplasmic-binding protein MntC precursor in E.coli. The MntC protein is also involved in the resistance to oxidative stress in N gonorrhoaeae. TREMBL E.coli:Q9F4F6. InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system periplasmic-binding protein	complement(668355..669284)	Azoarcus sp. BH72	4606491
YP_932145.1	CDS	mntB1	NC_008702.1	669287	670171	R	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system permease	complement(669287..670171)	Azoarcus sp. BH72	4609239
YP_932146.1	CDS	mntA1	NC_008702.1	670168	670938	R	Manganese transport system ATP-binding protein mntA. This protein is probably a component of a manganese permease a binding protein-dependent ATP-driven transport system (mntABC). Probably responsible for energy coupling to the transport system. 36% AAA_ATPase.IPR003439,AAA ATPase superfamily; ABC_transporter. Pfam: PF00005; ABC_tran; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system ATP-asa protein	complement(670168..670938)	Azoarcus sp. BH72	4609236
YP_932147.1	CDS	azo0643	NC_008702.1	670947	671174	R	Conserved hypothetical membrane protein. Homology to ebA1811 of Azoarcus sp. EbN1 of 38% (gi|56476415|ref|YP_158004.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(670947..671174)	Azoarcus sp. BH72	4609234
YP_932148.1	CDS	azo0644	NC_008702.1	671152	671676	R	Putative regulator protein, probably involved in the regulation of cation uptake systems. 32% FUR.IPR009058; Wing_hlx_DNA_bnd. Pfam:PF01475; FUR; 1.Fur family protein 30%; Function unclear; putative regulatory protein	complement(671152..671676)	Azoarcus sp. BH72	4606492
YP_932149.1	CDS	azo0645	NC_008702.1	671714	672076	R	Conserved hypothetical protein. Homology to PSPTO4639 of P.syringae of 41% (tremble:Q87WB4) No domains predicted. No TMHs. No signal peptide; hypothetical protein	complement(671714..672076)	Azoarcus sp. BH72	4606493
YP_932150.1	CDS	azo0646	NC_008702.1	672312	674498	D	HlyB-family protein. Similar to TREMBL:Q7WBM7 (50% identity); TREMBL:Q9KKL9 (41% identity); SWISSPROT:P18770 (28% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting four transmembrane helices. TC (3.A.1.109.3): LapA adhesin protein exporter, LapB.; High confidence in function and specificity; toxin secretion ABC transporter permease and ATP-binding protein	672312..674498	Azoarcus sp. BH72	4606494
YP_932151.1	CDS	hylD	NC_008702.1	674498	675913	D	Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership; HlyD family secretion protein	674498..675913	Azoarcus sp. BH72	4606495
YP_932152.1	CDS	azo0648	NC_008702.1	675910	676521	D	Putative DNA-binding response regulator, LuxR family,; Function unclear; LuxR family transcriptional regulator	675910..676521	Azoarcus sp. BH72	4609057
YP_932153.1	CDS	azo0649	NC_008702.1	676646	679489	D	Conserved hypothetical protein. Homology to ebA1795 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebA1795(KEGG)). No domains predicted. No TMHs.; hypothetical protein	676646..679489	Azoarcus sp. BH72	4606496
YP_932154.1	CDS	azo0650	NC_008702.1	679569	680795	D	Conserved hypothetical glycosyltransferase. Homology to gsu0991 of G. sulfurreducens of 30% (tremblnew|AAR34318) Pfam: Glycosyl transferase group 1 no signal peptide no TMHs; Conserved hypothetical protein; glycosyltransferase	679569..680795	Azoarcus sp. BH72	4606497
YP_932155.1	CDS	azo0651	NC_008702.1	680822	681160	D	Conserved hypothetical protein. Homology to ebB52 Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebB52(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	680822..681160	Azoarcus sp. BH72	4606498
YP_932156.1	CDS	azo0652	NC_008702.1	681161	683074	R	Conserved hypothetical GGDF domain protein. Homology to CV0310 of Chromobacterium violaceum of 34% (trembl|Q7P1A3). Has IPR003660_HAMP,SMART;SM00304:This domain is known as the HAMP domain for histidine kinases,adenylyl cyclases, methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160_GGDEF(SMART;SM00267);This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Has DUF2: This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site. It often but not always occurs along with PAS IPR000014 and DUF9 IPR000160 domains that are also found in many signalling proteins. signal peptide 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(681161..683074)	Azoarcus sp. BH72	4606499
YP_932157.1	CDS	azo0653	NC_008702.1	683109	683831	R	Conserved hypothetical secreted protein. Homology to BB1185 of Bordetella bronchiseptica of 49% (trembl|Q7WN55(SRS)) Signal peptide present. No TMHs Has PF06035, Bacterial protein of unknown function (DUF920);IPR010319; This family consists of several hypothetical bacterial proteins of unknown function.; Conserved hypothetical protein; hypothetical protein	complement(683109..683831)	Azoarcus sp. BH72	4606500
YP_932158.1	CDS	aggA	NC_008702.1	684035	685477	D	Putative outer membrane efflux protein. Homology to aggA from P. putida of 35%. The OEP family (outer membrane efflux protein) allow export of a variety of substrates in Gram negative bacteria. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Function unclear; putative outer membrane efflux protein	684035..685477	Azoarcus sp. BH72	4606501
YP_932159.1	CDS	azo0655	NC_008702.1	685558	689061	D	Putative two-component sensor histidine kinase. TrEMBL; Q87XU6( 47% identity, 64% similarity),Q6F9J5(43% identity,61% similarity),Q6NAD6(44% Identity,61% similarity). TMHMM2 reporting 2 TMH's present. No Signal peptide Present. Has PF02133;Permease for cytosine/purines, uracil, thiamine, allantoin: IPR001248;Cyt_pur_permease:The Nucleobase Cation Symporter-1 (NCS1) family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess twelve putative transmembrane a-helical spanners (TMSs). At least some of them have been shown to function in uptake by substrate:H+ symport mechanism. Has PF07578:Lipid A Biosynthesis N-terminal domain;This family is found at the N-terminus of a group of Chlamydial Lipid A biosynthesis proteins. It is also found by itself in a family of proteins of unknown function. Has SMART;SM00388:(IPR003661)Dimerisation and phosphoacceptor domain of histidine kinases.The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR003594;ATPbind_ATPase;(SM00387)This domain is found in several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins. SM00448;IPR001789;Response_reg:This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.; High confidence in function and specificity; putative two-component sensor histidine kinase	685558..689061	Azoarcus sp. BH72	4608286
YP_932160.1	CDS	azo0656	NC_008702.1	689058	690014	D	Putative transcriptional regulator, LuxR family,Response_reg. IPR000792; HTH_LuxR. Pfam: PF00072; response_reg. PF00196; GerE. SMART: SM00448; REC. SM00421; HTH_LUXR. HTH reporting reporting nucleic acid binding motif.; Family membership; LuxR family transcriptional regulator	689058..690014	Azoarcus sp. BH72	4606502
YP_932161.1	CDS	azo0657	NC_008702.1	691405	692367	D	Conserved hypothetical membrane protein. Homology to Raeut03005995 of Ralstonia eutropha of 34% (gi|53760601|ref|ZP_00350538.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 10 TMHs; Conserved hypothetical protein; hypothetical protein	691405..692367	Azoarcus sp. BH72	4606503
YP_932162.1	CDS	azo0658	NC_008702.1	692364	693995	D	Hypothetical membrane protein. No homology of the entire protein to the data bank. No domains predicted. No signal peptide. 12 TMHs; hypothetical protein	692364..693995	Azoarcus sp. BH72	4606504
YP_932163.1	CDS	gor	NC_008702.1	694005	695342	R	Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and specificity; glutathione-disulfide reductase	complement(694005..695342)	Azoarcus sp. BH72	4606505
YP_932164.1	CDS	azo0660	NC_008702.1	695491	697395	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q87G83 (52% identity); TREMBL:Q9K1A3 (61% identity); SWISSPROT:Q57180 (60% identity). Pfam (PF00005): ABC transporter. TMHMM reporting five transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear; ABC transporter permease and ATP-binding protein	695491..697395	Azoarcus sp. BH72	4608930
YP_932165.1	CDS	azo0661	NC_008702.1	697403	697951	D	Hypothetical protein ygjP. TREMBL:Q83JJ6: 60% identity,74% similarity (probable metal dependent hydrolase) Members of this family are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C terminus being the most conserved region, containing three conserved histidines InterPro:IPR002725; DUF45. Pfam:PF01863; DUF45 Non secretory protein with probability of signal peptide being 0.243 No transmembrane helices gmhA: phosphoheptose isomerase; High confidence in function and specificity; hypothetical protein	697403..697951	Azoarcus sp. BH72	4606506
YP_932166.1	CDS	azo0662	NC_008702.1	697992	698543	R	conserved hypothetical secreted protein. Homology to bA4595 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA4595(KEGG)) . No domains predicted. No TMHs. Signal Peptide present.; Conserved hypothetical protein; hypothetical protein	complement(697992..698543)	Azoarcus sp. BH72	4606507
YP_932167.1	CDS	azo0663	NC_008702.1	698767	699378	D	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. Entry name Q8PQ18 Primary accession number: Q8PQ18 InterPro IPR000462; CDP-OH_P_trans. Pfam PF01066; CDP-OH_P_transf; 1. Identities = 114/203 (56%),Prediction: Signal peptide Signal peptide probability: 0.988 Number of predicted TMHs: 3; Family membership; CDP-alcohol phosphatidyltransferase	698767..699378	Azoarcus sp. BH72	4606508
YP_932168.1	CDS	azo0664	NC_008702.1	699386	701152	D	Similar to TREMBL:Q87TY0 (64% identity); TREMBL:Q8PQ17 (61% identity); SWISSPROT:P76092 (55% identity).; hypothetical protein	699386..701152	Azoarcus sp. BH72	4606509
YP_932169.1	CDS	azo0665	NC_008702.1	701149	702507	D	Entry name:- Q9I0U5 Primary accession number:-Q9I0U5 InterPro:- IPR008934; AcPase_VanPerase. IPR000340; DS_phosphatase. IPR000326; PA_PTPase. Number of predicted TMHs: 8 Prediction: Non-secretory protein Signal peptide probability: 0.061 IPR000387; TYR_phosphatase. Pfam PF00782; DSPc; 1. PF01569; PAP2; 1. Identity:- 58%; hypothetical protein	701149..702507	Azoarcus sp. BH72	4606510
YP_932170.1	CDS	azo0666	NC_008702.1	702500	702943	D	Conserved hypothetical membrane protein. Homology to PA2538 of Pseudomonas aeruginosa of 36% (trembl|Q9I0U6). No domains predicted. No signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	702500..702943	Azoarcus sp. BH72	4606511
YP_932171.1	CDS	azo0667	NC_008702.1	702973	703596	D	FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-acyl carrier protein as the fatty acyl donor. CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:-SWISSPROT:PLSC_ECOLI Prim. accession # P26647 InterPro:-IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam:-PF01553; Acyltransferase; 1. Identities = 42/127 (33%) Prediction: Non-secretory protein Signal peptide probability: 0.014 Number of predicted TMHs: 0; Family membership; putative acyltransferase	702973..703596	Azoarcus sp. BH72	4606512
YP_932172.1	CDS	azo0668	NC_008702.1	703602	704546	D	Conserved hypothetical phoshpatidate cytidyltransferase. Homology to pa2536 of P. aeruginosa (trembl|Q9I0U8). Phosphatidate cytidylyltransferase is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate (PA): CTP + phosphatidate = diphosphate + CDP-diacylglycerol Pfam: Phospatidate cytidyltransferase signal peptide 7 TMHs InterPro: Phosphatidate cytidylyltransferase stp: serine transporter; Family membership; phosphatidate cytidylyltransferase	703602..704546	Azoarcus sp. BH72	4606513
YP_932173.1	CDS	napC1	NC_008702.1	704566	705237	R	Probable cytochrome c-type protein NapC. Homology to napC of r. sphaeroides of 67% (sprot|NAPC_RHOSH). MEDIATES ELECTRON FLOW FROM QUINONES TO THE NAPAB COMPLEX. signal peptide no TMHs; High confidence in function and specificity; cytochrome C-type protein NapC	complement(704566..705237)	Azoarcus sp. BH72	4606514
YP_932174.1	CDS	napB1	NC_008702.1	705250	705717	R	probable diheme cytochrome c. Homology to napB of A. eutrophus of 51% (sprot|NAPB_ALCEU). SMALL SUBUNIT OF THE PERIPLASMIC NITRATE REDUCTASE (NAP). ONLY EXPRESSED AT HIGH LEVELS DURING AEROBIC GROWTH. NAPAB COMPLEX RECEIVES ELECTRONS FROM THE MEMBRANE-ANCHORED TETRAHEME NAPC PROTEIN THUS ALLOWING ELECTRON FLOW BETWEEN MEMBRANE AND PERIPLASM. ESSENTIAL FUNCTION FOR NITRATE ASSIMILATION AND MAY HAVE A ROLE IN ANAEROBIC METABOLISM. signal peptide no TMHs; High confidence in function and specificity; diheme cytochrome C	complement(705250..705717)	Azoarcus sp. BH72	4609332
YP_932175.1	CDS	napA1	NC_008702.1	705728	708220	R	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit	complement(705728..708220)	Azoarcus sp. BH72	4609330
YP_932176.1	CDS	napD1	NC_008702.1	708192	708494	R	Putative NapD protein, component of of periplasmic nitrate reductase system. Plays a role in the correct assembly of subunits of the periplasmic napAB enzyme. Homology to napD of Rhodobacter sphaeroides of 26% (gi|3345484|dbj|AB016290.1|). InterPro:IPR005623; NapD. Pfam:PF03927; NapD; 1. no signal peptide. No TMHs.; Function unclear; putative NapD protein	complement(708192..708494)	Azoarcus sp. BH72	4609328
YP_932177.1	CDS	napE	NC_008702.1	708506	708664	R	Putative periplasmic nitrate reductase accessory protein NapE. Homology to napE of R. sphaeroides of 36% (trembl|O88159). Pfam: Periplasmic nitrate reductase NapE (PF06796) This family consists of several bacterial periplasmic nitrate reductase NapE proteins. NapE is thought to be a transmembrane protein of the reductase. Interpro: Periplasmic nitrate reductase NapE (IPR010649) no signal peptide 1 TMH; Family membership; putative periplasmic nitrate reductase accessory protein NapE	complement(708506..708664)	Azoarcus sp. BH72	4609334
YP_932178.1	CDS	amiC2	NC_008702.1	709010	710266	D	AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to trembl|Q87VQ0 (80%) and to sprot|AMIC_PSEAE (27%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative aliphatic amidase expression-regulating protein	709010..710266	Azoarcus sp. BH72	4609336
YP_932179.1	CDS	azo0675	NC_008702.1	710535	712166	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q87VP9 (50%)and to pir|AB0146 (48%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting nine Tmhelix. SignalP reporting Signal peptide.; Specificity unclear; ABC transporter permease	710535..712166	Azoarcus sp. BH72	4608309
YP_932180.1	CDS	urtC	NC_008702.1	712360	713553	D	Probable ABC transporter membrane spanning protein. Homology to urtC of Anabaena sp. of 41% (involved in urea transport). Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system signal peptide probable 9 TMHs; Function unclear; ABC transporter membrane protein	712360..713553	Azoarcus sp. BH72	4606515
YP_932181.1	CDS	urtD	NC_008702.1	713550	714407	D	Conserved hypothetical ABC transporter ATP binding protein. Homology to pp4844 of P. putida of 70% (trembl|Q88DI1). Probable component of a branched-chain amino-acid transport system. Pfam: ABC-Transporter no signal peptide no TMHs; Family membership; ABC transporter ATP-binding protein	713550..714407	Azoarcus sp. BH72	4610076
YP_932182.1	CDS	urtE	NC_008702.1	714834	715526	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q88DI0 (59%) and to sprot|BRAG_PSEAE (35%). Pfam: ABC transporter Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	714834..715526	Azoarcus sp. BH72	4610077
YP_932183.1	CDS	nodD	NC_008702.1	715560	716513	D	Probable nodulation protein,; Function unclear; nodulation protein	715560..716513	Azoarcus sp. BH72	4610078
YP_932184.1	CDS	caiD	NC_008702.1	716527	717309	R	Function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotobetainyl-CoA. Entry name CAID_ECO57 Primary accession number Q8XA35 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1. Identities = 30% Prediction: Non-secretory protein Signal peptide probability: 0.003 Number of predicted TMHs: 0; Family membership; putative carnitinyl-CoA dehydratase	complement(716527..717309)	Azoarcus sp. BH72	4609389
YP_932185.1	CDS	azo0681	NC_008702.1	717556	717876	D	Conserved hypothetical membrane protein. Homology to PP2796 of P. putida of 44% (trembl|Q88J53) PF04341,Protein of unknown function, DUF485;IPR007436;This family includes several putative integral membrane proteins. signal peptide 1 TMHs; Conserved hypothetical protein; hypothetical protein	717556..717876	Azoarcus sp. BH72	4608411
YP_932186.1	CDS	actP	NC_008702.1	717876	719555	D	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease	717876..719555	Azoarcus sp. BH72	4606516
YP_932187.1	CDS	ytfL1	NC_008702.1	719709	721004	D	Hypothetical protein ytfL. TREMBL:Q7NQ98: 61% identity, 78% similarity InterPro IPR002550; CBS. IPR000644; CBS_domain. IPR005170; CorC_transpt-asc. Pfam: PF00571; CBS; 2. PF03471; CorC_HlyC; PF01595; DUF21; gntP: gluconate transporter Signal peptide present (Signal P predicted) Transmembrane helices 4 (TMHMM predicted); High confidence in function and specificity; hemolysin	719709..721004	Azoarcus sp. BH72	4606517
YP_932188.1	CDS	mdcY	NC_008702.1	721389	722060	R	Transcriptional regulator, GntR-family,; High confidence in function and specificity; GntR family transcriptional regulator	complement(721389..722060)	Azoarcus sp. BH72	4610197
YP_932189.1	CDS	mutB	NC_008702.1	722387	724552	D	MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase	722387..724552	Azoarcus sp. BH72	4609205
YP_932190.1	CDS	argK	NC_008702.1	724619	725632	D	functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase	724619..725632	Azoarcus sp. BH72	4609295
YP_932191.1	CDS	pccB	NC_008702.1	725698	727233	D	Activity:- ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA Entry name:-TREMBL:Q8U9Y9 Prim. accession # Q8U9Y9 InterPro:-IPR000438; ACoACC_transB. IPR000022; Carboxyl_trans. Pfam:- PF01039; Carboxyl_trans; 1. Identities = 363/511 (71%) Number of predicted TMHs: 0; Family membership; propionyl-coa carboxylase subunit beta	725698..727233	Azoarcus sp. BH72	4608339
YP_932192.1	CDS	pccA	NC_008702.1	727372	729378	D	Activity:- ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA Entry name :- Q8U9Z4 Primary accession number:- Q8U9Z4 InterPro:- IPR001882; Biotin_BS. IPR005482; Biotin_carb_C. IPR000089; Biotin_lipoyl. IPR005481; CPase_L_N. IPR005479; Cphp_synth_L_D2. Pfam:- PF02785; Biotin_carb_C; 1. PF00364; Biotin_lipoyl; 1. PF00289; CPSase_L_chain; 1. PF02786; CPSase_L_D2; 1. Identities = 400/673 (59%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; propionyl-CoA carboxylase subunit alpha	727372..729378	Azoarcus sp. BH72	4609507
YP_932193.1	CDS	azo0689	NC_008702.1	729561	732017	D	GGEF/EAL/PAS/PAC-domain containing protein, sym; pNGR234a) / TREMBL: trembl|Q7NYX4 (40% Chromobacterium violaceum, cv1148) InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001633 EAL. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.; GGEF/EAL/PAS/PAC-domain-containing protein	729561..732017	Azoarcus sp. BH72	4609506
YP_932194.1	CDS	azo0690	NC_008702.1	732026	733909	D	Conserved hypothetical protein. Homology to PA4929 of P.aeruginosa of 32% (trembl|Q9HUN5(SRS)). Signal P reporting presence of signal peptide. 7 TMHs Has PF07696: 7TMR-DISM extracellular 2; This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives. Has PF07695:7TM diverse intracellular signalling domain;This entry represents the transmembrane region of the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules). Has IPR000160;GGDEF:(SM00267)This domain is found linked to a wide range of non-homologous domains. The function of this domain is unknown This domain is found in proteins which contain bacterial signaling domains. Has PF07696:7TMR-DISM extracellular 2 domain;This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives.; hypothetical protein	732026..733909	Azoarcus sp. BH72	4606518
YP_932195.1	CDS	azo0691	NC_008702.1	734005	734865	D	Conserved hypothetical metallopeptidase. Homology to bpp2257 of B. parapertussis of 63% (trembl|Q7W887). Members of this family of bacterial proteins are described as hypothetical proteins or zinc metallopeptidases. The majority have a HExxH zinc-binding motif characteristic of neutral zinc metallopeptidases, however there is no evidence to support their function as metallopeptidases. Pfam: putaive neutral zinc metallopeptidase no signal peptide 1 TMH; Specificity unclear; metallopeptidase	734005..734865	Azoarcus sp. BH72	4606519
YP_932196.1	CDS	gloA1	NC_008702.1	734887	735363	R	Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway in the following reaction: glutathione + methylglyoxal = (R)-S-lactoylglutathione,; Function unclear; lactoylglutathione lyase	complement(734887..735363)	Azoarcus sp. BH72	4606520
YP_932197.1	CDS	virG	NC_008702.1	735949	736680	R	Probable DNA-binding response regulator,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC.; Specificity unclear; DNA-binding response regulator	complement(735949..736680)	Azoarcus sp. BH72	4608907
YP_932198.1	CDS	azo0694	NC_008702.1	736677	738734	R	Putative hybrid sensor and regulator protein,; Specificity unclear; putative hybrid sensor and regulator protein	complement(736677..738734)	Azoarcus sp. BH72	4610094
YP_932199.1	CDS	oruR1	NC_008702.1	738888	739898	R	Putative ornithine utilization regulator,; Specificity unclear; putative ornithine utilization regulator	complement(738888..739898)	Azoarcus sp. BH72	4606521
YP_932200.1	CDS	azo0696	NC_008702.1	740204	743470	D	Methylmalonyl-CoA mutase mitochondrial precursor (EC 5.4.99.2) (MCM). INVOLVED IN MAN IN THE DEGRADATION OF SEVERAL AMINO ACIDS ODD-CHAIN FATTY ACIDS AND CHOLESTEROL VIA PROPIONYL-COA TO THE TRICARBOXYLIC ACID CYCLE. MCM HAS DIFFERENT FUNCTIONS IN OTHER SPECIES. Activity:- (R)-2-Methylmalonyl-CoA = succinyl-CoA Entry name :-TREMBL:Q8Y2U5 Prim. accession # Q8Y2U5 Identities = 797/1103 (72%) InterPro:- IPR006159; Acid_CoA_mut_C. IPR005129; ArgK. IPR006158; B12-binding. IPR006099; MMCoA_mutase. IPR006098; MMCoA_mutase_N. Pfam:- PF03308; ArgK; 1. PF02310; B12-binding; 1. PF01642; MM_CoA_mutase; 1. Prediction: Non-secretory protein Signal peptide probability: 0.005 Number of predicted TMHs: 0; Family membership; methylmalonyl-coa mutase	740204..743470	Azoarcus sp. BH72	4609458
YP_932201.1	CDS	azo0697	NC_008702.1	743567	743848	R	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	complement(743567..743848)	Azoarcus sp. BH72	4606522
YP_932202.1	CDS	fumC	NC_008702.1	743845	745224	R	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase	complement(743845..745224)	Azoarcus sp. BH72	4606523
YP_932203.1	CDS	azo0699	NC_008702.1	745304	746044	R	Hypothetical secreted protein. No significant homology to the data bank. no domains pedicted. signal peptide. TMH in signal peptide; hypothetical protein	complement(745304..746044)	Azoarcus sp. BH72	4608846
YP_932204.1	CDS	azo0700	NC_008702.1	746188	747486	R	Hypothetical protein, 52% identity to TrEMBL;Q8XYG9. Has PF03781, Domain of unknown function (DUF323);IPR005532 ;This presumed domain is found in bacterial proteins. In some cases these proteins also contain a protein kinase domain. The function of this domain is unknown. The domain has also been found in a eukaryotic protein, required for post-translational sulphatase modification.; Function unclear; hypothetical protein	complement(746188..747486)	Azoarcus sp. BH72	4606524
YP_932205.1	CDS	nagZ1	NC_008702.1	747598	748953	R	(N-acetyl-beta-glucosaminidase)(Beta-N- acetylhexosaminidase). Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity). Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D-glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta-GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. May play a role in signal transduction between host and organism. 34% Glyco_hydro_3N. Pfam:PF00933; Glyco_hydro_3; 1. TMhelix:2.; High confidence in function and specificity; putative beta-hexosaminidase	complement(747598..748953)	Azoarcus sp. BH72	4606525
YP_932206.1	CDS	creD	NC_008702.1	748950	750281	R	CreD confers tolerance to colicin E2. Similar to SWISSPROT:P08369 (35% identity). TMHMM reporting six transmembrane helices.; High confidence in function and specificity; hypothetical protein	complement(748950..750281)	Azoarcus sp. BH72	4609315
YP_932207.1	CDS	creC	NC_008702.1	750394	751824	R	part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC	complement(750394..751824)	Azoarcus sp. BH72	4608532
YP_932208.1	CDS	creB	NC_008702.1	751848	752555	R	response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB	complement(751848..752555)	Azoarcus sp. BH72	4608531
YP_932209.1	CDS	mgtE	NC_008702.1	752570	754012	R	Probable magnesium transporter MgtE. Members of this family probably transport Mg2+ or other divalent cations into the cell. 26% CBS_domain.IPR006667; MgtE_integrmembr. Pfam:PF00571; CBS; 2.PF01769; MgtE; 1. TMHleix: 3.; Function unclear; putative magnesium transport protein	complement(752570..754012)	Azoarcus sp. BH72	4608530
YP_932210.1	CDS	mtgA	NC_008702.1	754167	754862	R	glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase	complement(754167..754862)	Azoarcus sp. BH72	4609216
YP_932211.1	CDS	aroE	NC_008702.1	754859	755704	R	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase	complement(754859..755704)	Azoarcus sp. BH72	4609282
YP_932212.1	CDS	azo0708	NC_008702.1	755718	756620	R	Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(755718..756620)	Azoarcus sp. BH72	4608345
YP_932213.1	CDS	azo0709	NC_008702.1	756666	758567	R	Putative exoribonuclease II (EC: 3.1.13.1), RNase R / VacB protein) / TREMBL: trembl|Q7P1X0 (50% Chromobacterium violaceum, probable ribonuclease ll,cv0092) InterPro: IPR001900 Ribonuclease_II. Pfam: PF00773 RNB-like protein.; Conserved hypothetical protein; putative exoribonuclease II	complement(756666..758567)	Azoarcus sp. BH72	4606526
YP_932214.1	CDS	azo0710	NC_008702.1	758634	759479	R	Similar to TREMBL:Q8KNG7 (29% identity); TREMBL:Q8UEX8 (27% identity). Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear; putative methyltransferase	complement(758634..759479)	Azoarcus sp. BH72	4606527
YP_932215.1	CDS	azo0711	NC_008702.1	759510	760103	R	Conserrved hypothetical protein. Homology to rsc2781 of R. solanacearum of 51% (trembl|Q8XVP9) Pfam: UPF0227 Despite being classed as uncharacterised proteins,the members of this family are almost certainly enzymes that are distantly related to the Abhydrolase_1. no signal peptide no TMHs; hypothetical protein	complement(759510..760103)	Azoarcus sp. BH72	4606528
YP_932216.1	CDS	uppP	NC_008702.1	760137	760961	R	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase	complement(760137..760961)	Azoarcus sp. BH72	4606529
YP_932217.1	CDS	azo0713	NC_008702.1	761053	761304	R	Hypothetical protein PA1578.1. TREMBL:Q7W9P0:69% identity, 78% similarity TREMBL: Q8PDJ2: 69% identity, 74% similarity (predicted proteinase inhibitor)) Probable Fe-S cluster bearing oxidoreductase function. InterPro:IPR005358; UPF0153. Pfam:PF03692; UPF0153; High confidence in function and specificity; hypothetical protein	complement(761053..761304)	Azoarcus sp. BH72	4610069
YP_932218.1	CDS	azo0714	NC_008702.1	761309	761842	R	Conserved hypothetical protein. Homology to RPA1001 of R.palustris of 37% (tremble:Q6NB29). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(761309..761842)	Azoarcus sp. BH72	4606530
YP_932219.1	CDS	azo0715	NC_008702.1	761844	762548	R	Conserved hypothetical protein. Homology to DP0001 of Desulfotalea psychrophila of 43% (gnl|keqq|dps:DP0001(KEGG)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(761844..762548)	Azoarcus sp. BH72	4606531
YP_932220.1	CDS	hrpA	NC_008702.1	762691	766773	D	ATP-dependent helicase hrpA. Not yet known. InterPro: DEAD/DEAH box helicase; High confidence in function and specificity; putative ATP-dependent helicase	762691..766773	Azoarcus sp. BH72	4606532
YP_932221.1	CDS	azo0717	NC_008702.1	766798	767121	R	Conserved hypothetical secreted protein. Homology to ebA3912 of Azoarcus sp. EbN1 of 45% (gi|56477657|ref|YP_159246.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(766798..767121)	Azoarcus sp. BH72	4609029
YP_932222.1	CDS	rpsF	NC_008702.1	767369	767752	D	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6	767369..767752	Azoarcus sp. BH72	4606533
YP_932223.1	CDS	priB	NC_008702.1	767768	768079	D	Putative primosomal replication protein N Homology to priB of E. coli of 31% (sprot|PRIB_ECOLI) Component of the preprimosomal complex composed of priA, priB, priC,dnaB and dnaT. Upon transient interaction with dnaG it forms the primosome. Binds single-stranded DNA. Pfam: Single-stranded binding protein family (PF00436) Interpro: Single stranded binding (IPR010913) no signal peptide no TMHs; Family membership; putative primosomal replication proteinN	767768..768079	Azoarcus sp. BH72	4609809
YP_932224.1	CDS	rpsR	NC_008702.1	768081	768356	D	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18	768081..768356	Azoarcus sp. BH72	4609627
YP_932225.1	CDS	rplI	NC_008702.1	768375	768830	D	in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9	768375..768830	Azoarcus sp. BH72	4609821
YP_932226.1	CDS	dnaB	NC_008702.1	768968	770377	D	Replicative DNA helicase (EC 3.6.1.-). PARTICIPATES IN INITIATION AND ELONGATION DURING CHROMOSOME REPLICATION; IT EXHIBITS DNA-DEPENDENT ATPASE ACTIVITY AND CONTAINS DISTINCT ACTIVE SITES FOR ATP BINDING DNA BINDING AND INTERACTION WITH DNAC PROTEIN PRIMASE AND OTHER PREPRIMING PROTEINS. InterPro: DnaB helicase; High confidence in function and specificity; DnaB protein	768968..770377	Azoarcus sp. BH72	4609768
YP_932227.1	CDS	azo0723	NC_008702.1	776049	777212	D	Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity; ubiquinone biosynthesis hydroxylase family protein	776049..777212	Azoarcus sp. BH72	4608237
YP_932228.1	CDS	dsbC	NC_008702.1	777226	777951	D	Putative protein disulfide-isomerase. Homology to dsbC of E. coli of 29% (sprot|DSBC_ECOLI) REQUIRED FOR DISULFIDE BOND FORMATION IN SOME PERIPLASMIC PROTEINS. ACTS BY TRANSFERRING ITS DISULFIDE BOND TO OTHER PROTEINS AND IS REDUCED IN THE PROCESS. DSBC IS REOXIDIZED BY A YET UNCHARACTERIZED PROTEIN. ALSO ACTS AS A DISULFIDE ISOMERASE. signal peptide no TMHs; Family membership; putative protein disulfide-isomerase	777226..777951	Azoarcus sp. BH72	4606534
YP_932229.1	CDS	mltA	NC_008702.1	777974	779038	R	Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) (Murein hydrolase A) (Mlt38). MUREIN-DEGRADING ENZYME. MAY PLAY A ROLE IN RECYCLING OF MUROPEPTIDES DURING CELL ELONGATION AND/OR CELL DIVISION. OPTIMAL ACTIVITY IS BETWEEN PH 4.0 AND 4.5; LOSES ITS ACTIVITY RAPIDLY AT TEMPERATURES ABOVE 30 DEGREES CELSIUS. DEGRADES MUREIN GLYCAN STRANDS AND INSOLUBLE HIGH-MOLECULAR WEIGHT MUREIN SACCULI. ssl1: transcription factor ssl1; High confidence in function and specificity; membrane-bound transglycosylase	complement(777974..779038)	Azoarcus sp. BH72	4608655
YP_932230.1	CDS	azo0726	NC_008702.1	779280	779393	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	779280..779393	Azoarcus sp. BH72	4609227
YP_932231.1	CDS	azo0727	NC_008702.1	779386	780249	D	Conserved hypothetical ATPase family protein. Homology to bb4427 of B. bronchiseptica of 65% (trembl|Q7WF53). Pfam: ATPase family associated with various cellular activities This large family has the key feature that they share a conserved region of about 220 amino acids that contains an ATP-binding site. no signal peptide no TMHs; Conserved hypothetical protein; ATPase family protein	779386..780249	Azoarcus sp. BH72	4606535
YP_932232.1	CDS	azo0728	NC_008702.1	780242	781198	D	NUDIX hydrolase/thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity). InterPro: NUDIX hydrolase TIGRFAM: mutt: mutator mutT protein; High confidence in function and specificity; hypothetical protein	780242..781198	Azoarcus sp. BH72	4606536
YP_932233.1	CDS	azo0729	NC_008702.1	781195	781395	R	Conserved hypothetical protein. Homology to RSc2830 of Ralstonia solanacearum of 53% (trembl:Q8XVK0). Has PF03884, Domain of unknown function (DUF329);IPR005584;The function of this short domain is unknown it contains four conserved cysteines and may therefore be involved in zinc binding. no TMHs. No signal peptide.; hypothetical protein	complement(781195..781395)	Azoarcus sp. BH72	4606537
YP_932234.1	CDS	yacF	NC_008702.1	781398	782153	R	Hypothetical protein, yacF, 32% identitcal to SwissProt;P36680,Q8FL56. Has PF07072, Protein of unknown function (DUF1342);IPR009777 ;This family consists of several hypothetical bacterial proteins of around 250 residues in length. Members of this family are often known as YacF after the Escherichia coli protein P36680. The function of this family is unknown. cobA: cob(I)alamin adenosyltransferase; hypothetical protein	complement(781398..782153)	Azoarcus sp. BH72	4606538
YP_932235.1	CDS	coaE	NC_008702.1	782235	782855	R	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase	complement(782235..782855)	Azoarcus sp. BH72	4610135
YP_932236.1	CDS	azo0732	NC_008702.1	782852	783562	R	Conserved hypothetical secreted protein. Homology to rs03277 of R. solanacearum of 30% (TrEMBL:Q8Y2M5). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(782852..783562)	Azoarcus sp. BH72	4608496
YP_932237.1	CDS	baf	NC_008702.1	783572	784363	R	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase	complement(783572..784363)	Azoarcus sp. BH72	4606539
YP_932238.1	CDS	birA	NC_008702.1	784360	785088	R	BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. birA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-coa:carbon- dioxide ligase. this protein also activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins. InterPro: Biotin--acetyl-CoA-carboxylase ligase birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear; biotin--[acetyl-CoA-carboxylase] ligase	complement(784360..785088)	Azoarcus sp. BH72	4608375
YP_932239.1	CDS	ntrC	NC_008702.1	785250	786680	R	Nitrogen regulation protein NR(I),; High confidence in function and specificity; nitrogen regulation protein NR(I)	complement(785250..786680)	Azoarcus sp. BH72	4608396
YP_932240.1	CDS	ntrB	NC_008702.1	786724	787797	R	Nitrogen regulation protein NR(II),; High confidence in function and specificity; nitrogen regulation protein NR(II)	complement(786724..787797)	Azoarcus sp. BH72	4609414
YP_932241.1	CDS	azo0737	NC_008702.1	787859	788335	R	Conserved hypothetical secreted protein. Homology to cv3590 of C. violaceum of 39% (trembl|Q7NS37(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(787859..788335)	Azoarcus sp. BH72	4609413
YP_932242.1	CDS	glnA	NC_008702.1	788464	789873	R	Glutamine synthetase I (GS) plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to pir|G83005 (70%) and to pir|AJECQ (66%). Pfam (PF00120): Glutamine synthetase, catalytic domain Pfam (PF03951): Glutamine synthetase, beta-Grasp domain; High confidence in function and specificity; glutamine synthetase	complement(788464..789873)	Azoarcus sp. BH72	4606540
YP_932243.1	CDS	czcD1	NC_008702.1	790055	791269	R	CzcD: Members of this family (TC 2.A.4) are integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc,and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. (Slc30a subfamily). Similar to the cobalt-zinc-cadmium resistance protein CzcD (cation efflux system protein) from Alcaligenes eutrophus (Ralstonia eutropha). SWISSPROT:CZCD_ALCEU.P13512. InterPro:IPR002524; Cation_efflux.InterPro: Cation efflux family. Pfam:PF01545; Cation_efflux; 1. TIGRFAMs:TIGR01297; CDF; 1. TMHelix: 4.; High confidence in function and specificity; putative cobalt-zinc-cadmium resistance protein	complement(790055..791269)	Azoarcus sp. BH72	4608894
YP_932244.1	CDS	azo0740	NC_008702.1	791287	791739	D	Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. InterPro: Rhodanese/cdc25 fold; Specificity unclear; putative sulfurtransferase	791287..791739	Azoarcus sp. BH72	4608573
YP_932245.1	CDS	nadA	NC_008702.1	791814	792914	D	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase	791814..792914	Azoarcus sp. BH72	4606541
YP_932246.1	CDS	azo0742	NC_008702.1	792936	793685	D	Conserved hypothetical protein. Homology to rs04427 of R. solanacearum of 55% (trembl|Q8Y267). Pfam: Endonuclease/Exonuclease/phosphatase family (PF03372). Interpro: Endonuclease/Exonuclease/phosphatase family (IPR005135). no signal peptide. no TMHs; hypothetical protein	792936..793685	Azoarcus sp. BH72	4609302
YP_932247.1	CDS	cls1	NC_008702.1	793682	794839	D	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Affects resistance to the gyrase inhibitor novobiocin. Entry name: CLS_ECOLI Primary accession number P31071 InterPro IPR001736; PLD. Pfam PF00614; PLDc; 2 Identity:- 28% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; putative cardiolipin synthetase	793682..794839	Azoarcus sp. BH72	4606542
YP_932248.1	CDS	azo0744	NC_008702.1	794846	795355	R	Protein yccU. TREMBL:Q982W3: 50% identity, 70% similarity. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. InterPro:IPR003781; CoA_binding. Pfam: PF02629; CoA_binding FRU: PTS enzyme-IIB fructose permease No signal peptide. No transmembrane helices present.; Function unclear; hypothetical protein	complement(794846..795355)	Azoarcus sp. BH72	4608492
YP_932249.1	CDS	azo0745	NC_008702.1	795366	796367	R	Putative glutamyl-tRNA synthetase-related protein,58% identity to TrEMBl; Q5P2J9,47% identity to TrEMBL; Q7NSJ1. Has PF00749, tRNA synthetases class I (E and Q),catalytic domain.Other tRNA synthetase sub-families are too dis; Specificity unclear; glutamate-tRNA ligase	complement(795366..796367)	Azoarcus sp. BH72	4606543
YP_932250.1	CDS	azo0746	NC_008702.1	796481	798106	D	Hypothetical membrane protein. Homology to la0834 of L. interrogans of 25% (trembl|Q8F7U9). InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase (IPR003342). Dolichyl-phosphate-mannose-protein mannosyltransferases belong to the glycosyltransferase family 39 and are responsible for O-linked glycosylation of proteins. They catalyse the reaction: Dolichyl phosphate D-mannose + protein -> dolichyl phosphate + O-D-mannosyl-protein. Pfam: Dolichyl-phosphate-mannose-protein mannosyltransferase. signal peptide. 10 TMHs; hypothetical protein	796481..798106	Azoarcus sp. BH72	4606544
YP_932251.1	CDS	azo0747	NC_008702.1	798162	799442	D	40% GH_BNR. Pfam:PF02012; BNR; 2. TMHelix:1. Signal peptide: present.; Function unclear; hypothetical protein	798162..799442	Azoarcus sp. BH72	4606545
YP_932252.1	CDS	azo0748	NC_008702.1	799936	800856	R	Probable cellobiose phosphorylase, 31% identity to TrEMBL;Q7NYW4. Has PF04794, YdjC-like protein;IPR006879; Family of YdjC-like proteins. This region is possibly involved in the the cleavage of cellobiose-phosphate.; Function unclear; cellobiose phosphorylase	complement(799936..800856)	Azoarcus sp. BH72	4606546
YP_932253.1	CDS	azo0749	NC_008702.1	800954	801982	D	Conserved hypothetical glycosyl transferase. Homology to cc2889 of. C. crescentus (trembl|Q9A4E5). Pfam: Glycosyl transferase family 2(PF00535). Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. Interpro: Glycosyl transferase family 2 (IPR001173). no signal peptide. 2 TMHs.; Conserved hypothetical protein; glycosyl transferase family protein	800954..801982	Azoarcus sp. BH72	4606547
YP_932254.1	CDS	azo0750	NC_008702.1	802057	803655	D	Conserved hypothetical membrane protein. TREMBL:Q89QQ8: 34% identity This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permeases involved in the transport across the membrane of several compounds. This entry contains the inner components of this multicomponent transport system InterPro: IPR000522; FecD. Pfam: PF01032; FecCD ncs1: NCS1 nucleoside transporter fam Nonsecretory protein with signal peptide probability 0.203 (Signal P predicted). TMHMM predicted 9 transmembrane helices.; Function unclear; hypothetical protein	802057..803655	Azoarcus sp. BH72	4606548
YP_932255.1	CDS	azo0751	NC_008702.1	803652	804053	D	Conserved hypothetical membrane protein. Homology to PA4820 of P. aeruginosa of 38% (trembl|Q9HUZ0(SRS)) Has PF04138, GtrA-like protein;IPR007267;Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. no signal peptide 4 TMHs; Conserved hypothetical protein; hypothetical protein	803652..804053	Azoarcus sp. BH72	4606549
YP_932256.1	CDS	ychF	NC_008702.1	804105	805196	R	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD	complement(804105..805196)	Azoarcus sp. BH72	4606550
YP_932257.1	CDS	pth	NC_008702.1	805193	805849	R	Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase	complement(805193..805849)	Azoarcus sp. BH72	4610159
YP_932258.1	CDS	rplY	NC_008702.1	805889	806491	R	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc	complement(805889..806491)	Azoarcus sp. BH72	4609646
YP_932259.1	CDS	prsA	NC_008702.1	806573	807523	R	Ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase); High confidence in function and specificity; ribose-phosphate diphosphokinase	complement(806573..807523)	Azoarcus sp. BH72	4609784
YP_932260.1	CDS	ipk	NC_008702.1	807698	808546	R	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	complement(807698..808546)	Azoarcus sp. BH72	4609990
YP_932261.1	CDS	lolB	NC_008702.1	808543	809124	R	conserved hypothetical outer-membrane lipoprotein. Homology to lolB of C. violaceum of 32% (sprot|LOLB_CHRVO) Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein (By similarity). Tigrfam: lolB: outer membrane lipoprotein LolB Pfam: outer membrane lipoprotein LolB signal peptide no TMHs; Family membership; outer membrane lipoprotein	complement(808543..809124)	Azoarcus sp. BH72	4609096
YP_932262.1	CDS	azo0758	NC_008702.1	809121	810836	R	Conserved hypothetical secreted protein. Homology to cv4061 of C. violaceum of 37% (trembl|Q7NQS6). InterPro: TPR repeat (IPR001440) signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(809121..810836)	Azoarcus sp. BH72	4609169
YP_932263.1	CDS	mutM	NC_008702.1	810989	811807	D	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase	810989..811807	Azoarcus sp. BH72	4606551
YP_932264.1	CDS	azo0760	NC_008702.1	811931	813898	D	TREMBL:Q8Y2D6:42% identity, 59% similarity Hypothetical protein in xynA 3region (ORF6) (Fragment). Pfam:dynamin_2 :Dynamin central region; FH2:Formin Homology 2 Domain surE: stationary-phase survival prote No transmembrane helices(TMHMM predicted); Function unclear; hypothetical protein	811931..813898	Azoarcus sp. BH72	4609297
YP_932265.1	CDS	fdx1	NC_008702.1	813966	814223	R	Probable ferredoxin. Homology to fdx of C. vinosum of 67% (sprot|FER_CHRVI). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership; ferredoxin	complement(813966..814223)	Azoarcus sp. BH72	4606552
YP_932266.1	CDS	coaD	NC_008702.1	814240	814731	R	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase	complement(814240..814731)	Azoarcus sp. BH72	4608745
YP_932267.1	CDS	azo0763	NC_008702.1	814728	815249	R	Putative methylase; Family membership; putative methylase	complement(814728..815249)	Azoarcus sp. BH72	4608495
YP_932268.1	CDS	azo0764	NC_008702.1	815264	816616	R	Hypothetical zinc protease-like protein y4wB. TREMBL:Q8Y2E8: 43% identity; 57% similarity. InterPro: Insulinase family (Peptidase family M16) InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. Pfam:PF00675; Peptidase_M16 (Insulinase); homoserine_dh; aldehyde dehydrogenase; PF05193:Peptidase_M16_C; precor6x_red: precorrin-6x reductase TIGRFAM:folate/biopterin transporter SignalP predicted signal peptide and TMHMM predicted transmembrane helix; Specificity unclear; Zn dependent peptidase	complement(815264..816616)	Azoarcus sp. BH72	4606553
YP_932269.1	CDS	azo0765	NC_008702.1	816645	818111	R	TREMBL:Q8Y2E9: 55% identity, 68% similarity. Hypothetical zinc protease y4wA. InterPro:IPR001431; Peptidase_M16. IPR007863: Peptidase_M16_C. cofactor:binds 1 zinc ion per subunit (by similarity). belongs to peptidase family m16. similarity:to y4wb. Pfam:PF00675; Peptidase_M16; 1. PF05193:Peptidase_M16_C TIGRFAM: uxuA SignalP predicted signal peptide and TMHMM predicted transmembrane helices menD: 2-succinyl-6-hydroxy-24-cyclohex; Specificity unclear; Zn dependent peptidase	complement(816645..818111)	Azoarcus sp. BH72	4606554
YP_932270.1	CDS	FtsY	NC_008702.1	818232	819365	D	Probable signal recognition particle-docing protein FtsY Homology to ftsY of C. violaceum of 65% (trembl|Q7NQD7) In E.coli, ftsY is an essential gene located in an operon with cell division genes ftsE and ftsX, but its apparent function is as the signal recognition particle docking protein. Pfam: SRP54-type protein, helical bundle domain (PF02881); SRP54-type protein, GTPase domain Tigrfam: ftsY: signal recognition particale-docking protein FtsY no signal peptide no TMHs; High confidence in function and specificity; signal recognition particle-docing protein FtsY	818232..819365	Azoarcus sp. BH72	4606555
YP_932271.1	CDS	FtsE	NC_008702.1	819362	820021	D	High confidence in function and specificity; cell division ATP-binding protein FtsE	819362..820021	Azoarcus sp. BH72	4608842
YP_932272.1	CDS	FtsX	NC_008702.1	820018	820914	D	Putative cell division protein FtsX. Homology to ftsX of E. coli of 33% (sprot|FTSX_ECOLI). FtsX is an integral membrane protein encoded in the same operon as signal recognition particle docking protein FtsY and FtsE. Might be a permease. Tigrfam: ftsX: cell division ABC transporter protein probable signal peptide probable 4 TMHs; Family membership; cell division protein FtsX	820018..820914	Azoarcus sp. BH72	4608833
YP_932273.1	CDS	ahpC	NC_008702.1	821109	821672	D	Alkyl hydroperoxide reductase subunit C. Homology to aphC of X. campestris of 84% (trembl|O06464). Directly reduces organic hydroperoxides in its reduced dithiol form. InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) Pfam: AhpC/TSA family no signal peptide no TMHs; High confidence in function and specificity; alkyl hydroperoxide reductase subunit C	821109..821672	Azoarcus sp. BH72	4608841
YP_932274.1	CDS	ahpF	NC_008702.1	821802	823355	D	Alkyl hydroperoxide reductase subunit F. Homology to aphF of X. campestris of 71% (sprot|AHPF_XANCH) Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AHPC protein. Pfam: Pyridine nucleotide-disulphide oxidareductase no TMHs; High confidence in function and specificity; alkyl hydroperoxide reductase subunit F	821802..823355	Azoarcus sp. BH72	4608287
YP_932275.1	CDS	azo0771	NC_008702.1	824754	826058	R	Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase; C-5 cytosine-specific DNA methylase	complement(824754..826058)	Azoarcus sp. BH72	4608288
YP_932276.1	CDS	rnhA1	NC_008702.1	826594	827043	R	Ribonuclease H (EC 3.1.26.4) (RNase H). This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically (By similarity). InterPro: RNase H; High confidence in function and specificity; RnhA1 protein	complement(826594..827043)	Azoarcus sp. BH72	4606556
YP_932277.1	CDS	azo0773	NC_008702.1	827040	827819	R	Hypothetical protein , 32% identity to TrEMBL;Q8NZP4 No domains, repeats, motifs or features present.; hypothetical protein	complement(827040..827819)	Azoarcus sp. BH72	4609752
YP_932278.1	CDS	azo0774	NC_008702.1	828127	828822	R	hypothetical protein	complement(828127..828822)	Azoarcus sp. BH72	4606557
YP_932279.1	CDS	azo0775	NC_008702.1	829733	830302	R	Putative DNA-invertase from lambdoid prophage Rac. InterPro: Site-specific recombinase Pfam: Resolvase; Family membership; putative resolvase	complement(829733..830302)	Azoarcus sp. BH72	4606558
YP_932280.1	CDS	azo0776	NC_008702.1	830685	832355	R	Family membership; putative integrase	complement(830685..832355)	Azoarcus sp. BH72	4606559
YP_932281.1	CDS	azo0777	NC_008702.1	832729	833076	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	832729..833076	Azoarcus sp. BH72	4610010
YP_932282.1	CDS	azo0778	NC_008702.1	833091	834440	D	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase	833091..834440	Azoarcus sp. BH72	4606561
YP_932283.1	CDS	ybeZ	NC_008702.1	834440	835423	D	PhoH-like protein,; High confidence in function and specificity; PhoH-like protein	834440..835423	Azoarcus sp. BH72	4606562
YP_932284.2	CDS	azo0780	NC_008702.1	835359	836174	D	contains unknown N-terminal domain/putative metalloprotease C-terminal domain; unkown domain/metalloprotease fusion protein	835359..836174	Azoarcus sp. BH72	4610147
YP_932285.1	CDS	corC	NC_008702.1	836270	837115	D	Magnesium and cobalt efflux protein corC. Plays a role in the transport of magnesium and cobalt ions. Also mediates transport of cobalt and nickel. 43% CBS_domain.IPR005170; CorC_transpt-asc. Pfam:PF00571; CBS; 2.PF03471; CorC_HlyC; 1. Belongs to the UPF0053 family.Contains 2 cbs domains.; High confidence in function and specificity; putative magnesium and cobalt efflux protein	836270..837115	Azoarcus sp. BH72	4606563
YP_932286.1	CDS	lnt	NC_008702.1	837115	838629	D	Putative apolipoprotein N-acyltransferase. Homology to cutE of E. coli of 36% (sprot|LNT_ECOLI). Transfers the fatty acyl group on membrane lipoproteins. InterPro: Apolipoprotein N-acyltransferase (IPR004563); Carbon-nitrogen hydrolase (IPR003010) Tigrfam: lnt: apolipoprotein N-acyltransferase Pfam: Carbon-nitrogen hydrolase signal peptide 6 TMHs; High confidence in function and specificity; putative apolipoprotein N-acyltransferase	837115..838629	Azoarcus sp. BH72	4608519
YP_932287.1	CDS	azo0783	NC_008702.1	838754	839893	D	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7NHP0 (27% identity); SignalP predicting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership; membrane fusion protein	838754..839893	Azoarcus sp. BH72	4609167
YP_932288.1	CDS	azo0784	NC_008702.1	839904	842957	D	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A3K6 (38% identity); TREMBL:Q89XF8 (40% identity). InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	839904..842957	Azoarcus sp. BH72	4606564
YP_932289.1	CDS	glyQ	NC_008702.1	843084	844010	D	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha	843084..844010	Azoarcus sp. BH72	4606565
YP_932290.1	CDS	glyS	NC_008702.1	844007	846094	D	Glycyl-tRNA synthetase beta chain (EC 6.1.1.14) (Glycine--tRNA ligase beta chain) (GlyRS).; High confidence in function and specificity; glycyl-tRNA synthetase subunit beta	844007..846094	Azoarcus sp. BH72	4606566
YP_932291.1	CDS	azo0787	NC_008702.1	846144	846677	D	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase	846144..846677	Azoarcus sp. BH72	4608925
YP_932292.1	CDS	azo0788	NC_008702.1	846695	847453	D	Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:- Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:- IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership; acyltransferase	846695..847453	Azoarcus sp. BH72	4606567
YP_932293.1	CDS	azo0789	NC_008702.1	847542	848102	R	Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 69% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; Family membership; phasin	complement(847542..848102)	Azoarcus sp. BH72	4606568
YP_932294.1	CDS	paaF1	NC_008702.1	848399	849175	R	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	complement(848399..849175)	Azoarcus sp. BH72	4606569
YP_932295.1	CDS	azo0791	NC_008702.1	849202	849774	R	Conserved hypothetical secreted protein. Homology to rsc0410 of R. solanacearum of 42% (trembl|Q8Y2C6(SRS)) Pfam: OstA-like protein This family of proteins are mostly uncharacterised. However the family does include E. coli OstA P31554 that has been characterised as an organic solvent tolerance protein. signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(849202..849774)	Azoarcus sp. BH72	4609470
YP_932296.1	CDS	azo0792	NC_008702.1	849771	850349	R	Conserved hypothetical secreted protein. Homology to ebA1318 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA1318(KEGG)). Has PF06835, Protein of unknown function (DUF1239);IPR010664;This family consists of several hypothetical bacterial proteins of around 190 residues in length. The function of this family is unknown. No TMHs. Signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(849771..850349)	Azoarcus sp. BH72	4606570
YP_932297.1	CDS	azo0793	NC_008702.1	850359	850880	R	Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices.; Specificity unclear; phosphatase	complement(850359..850880)	Azoarcus sp. BH72	4606571
YP_932298.1	CDS	azo0794	NC_008702.1	850880	851875	R	Arabinose 5-phosphate isomerase (EC 5.3.1.13). Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate (By similarity). InterPro: KpsF/GutQ family protein kpsF: KpsF/GutQ family protein; High confidence in function and specificity; sugar-phosphate isomerase	complement(850880..851875)	Azoarcus sp. BH72	4606572
YP_932299.1	CDS	azo0795	NC_008702.1	852075	854042	D	Probable glutathione-regulated potassium-efflux system protein (K(+)/H(+) antiporter). Transport system that facilitate potassium-efflux possibly by potassium-proton antiport. 50% Na_H_porter.IPR006037; TrkAC.IPR003148; TrkA_N. Pfam: PF00999; Na_H_Exchanger; 1.PF02080; TrkA_C; 1.PF02254; TrkA_N; 1. TMhelix: 11.; High confidence in function and specificity; putative glutathione-regulated potassium-efflux system protein	852075..854042	Azoarcus sp. BH72	4606573
YP_932300.1	CDS	azo0796	NC_008702.1	854050	854697	R	Conserved hypothetical membrabe protein. Homology to Mflag03002444 of Methylobacillus flagellatus of 48% (gi|46120631|ref|ZP_00201765.1|(NBCI ENTREZ)). no domains predicted. No signal peptide. 1 TMHs; hypothetical protein	complement(854050..854697)	Azoarcus sp. BH72	4606574
YP_932301.1	CDS	azo0797	NC_008702.1	854732	855430	R	Conserved hypothetical secreted protein. Homology to Daro03002886 of Dechloromonas aromatica of 31% (gi|53729825|ref|ZP_00150246.2|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide.; hypothetical protein	complement(854732..855430)	Azoarcus sp. BH72	4606575
YP_932302.1	CDS	azo0798	NC_008702.1	855418	856656	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(855418..856656)	Azoarcus sp. BH72	4606576
YP_932303.1	CDS	azo0799	NC_008702.1	856671	857057	R	Hypothetical secreted protein. no homology with the data bank. no domains predicted. signal peptide. no TMHS; hypothetical protein	complement(856671..857057)	Azoarcus sp. BH72	4606577
YP_932304.1	CDS	azo0800	NC_008702.1	857054	857644	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(857054..857644)	Azoarcus sp. BH72	4606578
YP_932305.1	CDS	azo0801	NC_008702.1	857641	859065	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide present. 1 TMH present.; hypothetical protein	complement(857641..859065)	Azoarcus sp. BH72	4606579
YP_932306.1	CDS	gspF1	NC_008702.1	859072	860277	R	Type II secretory pathway component F,; Specificity unclear; general secretion pathway protein F	complement(859072..860277)	Azoarcus sp. BH72	4606580
YP_932307.1	CDS	gspE1	NC_008702.1	860274	861974	R	Bacterial type II secretion system protein E,; Specificity unclear; general secretion pathway protein E	complement(860274..861974)	Azoarcus sp. BH72	4608952
YP_932308.1	CDS	azo0804	NC_008702.1	861980	862615	R	Hypothetical protein. No homology to a protein of similar size. No domains predicted. No signal peptide. No TMHs; hypothetical protein	complement(861980..862615)	Azoarcus sp. BH72	4608949
YP_932309.1	CDS	gspD1	NC_008702.1	862681	864423	R	Type II secretory pathway component D, weak similarity to SWISSPROT:HOFQ_ECOLI (18%). A number of proteins are involved in the general secretion pathway (GSP); one of these is known as protein D (GSPD protein). Protein D is involved in the type II general secretion pathway within Gram-negative bacteria, a signal sequence-dependent process responsible for protein export. InterPro (PF00263): General (type II) secretion pathway (GSP) D protein; Specificity unclear; general secretion pathway protein D	complement(862681..864423)	Azoarcus sp. BH72	4606581
YP_932310.1	CDS	azo0806	NC_008702.1	864497	865330	D	Conserved hypothetical ABC transporter ATP-binding protein. Homology to rs01335 of R. solanacearum of 67% (trembl|Q8XV69). ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. They are minimally composed of four domains, with two transmembrane domains (TMDs) responsible for allocrite binding and transport and two nucleotide-binding domains (NBDs) responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Both NBDs are capable of ATP hydrolysis. Pfam: ABC transporter (PF00005). No signal peptide. No TMHs; Family membership; ABC transporter ATP-binding protein	864497..865330	Azoarcus sp. BH72	4608947
YP_932311.1	CDS	azo0807	NC_008702.1	865327	866118	D	Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.; hypothetical protein	865327..866118	Azoarcus sp. BH72	4606582
YP_932312.1	CDS	azo0808	NC_008702.1	866118	866591	D	Conserved hypothetical secreted protein. Similar to TREMBL:Q8XV71 (59% identity); TREMBL:Q82SF7 (55% identity); TREMBL:Q7VSZ8 (55% identity). Pfam (PF02470): mce related protein. This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within,the macrophage. This family contains proteins of unknown function from other bacteria. SignalP reoprting signal peptide. TMH in signal peptide; Family membership; hypothetical protein	866118..866591	Azoarcus sp. BH72	4606583
YP_932313.1	CDS	vacJ	NC_008702.1	866632	867492	D	Putative surface lipoprotein. Homology to vacJ of S. flexneri of 26% (sprot|VACJ_SHIFL) Required for intercellular spreading. Pfam: VacJ like lipoprotein signal peptide no TMHs; Family membership; putative surface lipoprotein	866632..867492	Azoarcus sp. BH72	4606584
YP_932314.1	CDS	azo0810	NC_008702.1	867498	868145	D	Conserved hypothetical secreted protein. Similar to TREMBL:Q82SF8 (54% identity); TREMBL:Q8XV73 (42% identity); TREMBL:Q7VSZ6 (40% identity). SignalP reporting signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	867498..868145	Azoarcus sp. BH72	4610088
YP_932315.1	CDS	azo0811	NC_008702.1	868216	868497	D	Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs; hypothetical protein	868216..868497	Azoarcus sp. BH72	4606585
YP_932316.1	CDS	azo0812	NC_008702.1	868505	869401	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7P0X8 (62% identity); TREMBL:Q82SG0 (58% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; ABC transporter ATP-binding protein	868505..869401	Azoarcus sp. BH72	4606586
YP_932317.1	CDS	azo0813	NC_008702.1	869394	870194	D	Similar to TREMBL:Q8XV76 (69% identity); TREMBL:Q7P0X7 (66% identity); TREMBL:Q82SG1 (64% identity). InterPro (IPR000412): ABC transporter family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear; ABC-2 type transporter permease	869394..870194	Azoarcus sp. BH72	4606587
YP_932318.1	CDS	azo0814	NC_008702.1	870223	870480	D	Conserved hypothetical BolA-like protein. Homology to ne2377 of N. europaea of 47% (trembl|Q82SG2). InterPro: BolA-like protein This family consist of the morphoprotein BolA from E. coli and its various homologues. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5. Pfam: BolA-like binding protein no signal peptide no TMHs; Function unclear; BolA-like protein	870223..870480	Azoarcus sp. BH72	4606588
YP_932319.1	CDS	murA	NC_008702.1	870517	871767	D	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	870517..871767	Azoarcus sp. BH72	4606589
YP_932320.1	CDS	rnk	NC_008702.1	871799	872206	R	Regulator of nucleoside diphosphate kinase. RNK AND SSPA CAN FUNCTIONALLY REPLACE P.AERUGINOSA ALGINATE REGULATORY GENE ALGR2. 49% 1.; High confidence in function and specificity; putative regulator of nucleoside diphosphate kinase	complement(871799..872206)	Azoarcus sp. BH72	4609287
YP_932321.1	CDS	hisG	NC_008702.1	872316	872990	D	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit	872316..872990	Azoarcus sp. BH72	4609755
YP_932322.1	CDS	hisD	NC_008702.1	872987	874297	D	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase	872987..874297	Azoarcus sp. BH72	4609006
YP_932323.1	CDS	aspC	NC_008702.1	874352	875542	R	Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes,such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies; these sequences are defined by the aminotransferases class-I pyridoxal-phosphate attachment site signature, which contains the lysine residue involved in pyridoxal-phosphate binding. Similar to pir|D83057 (55%) and to trembl|Q8P544 (55%). Pfam (PF00155): Aminotransferases class-I pyridoxal-phosphate-binding site HTH reporting nucleic acid binding motif.; Specificity unclear; hypothetical protein	complement(874352..875542)	Azoarcus sp. BH72	4609003
YP_932324.1	CDS	pckG	NC_008702.1	875655	877499	R	catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase	complement(875655..877499)	Azoarcus sp. BH72	4608361
YP_932325.1	CDS	maeB1	NC_008702.1	877831	880107	D	NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate; malic enzyme	877831..880107	Azoarcus sp. BH72	4609509
YP_932326.1	CDS	azo0822	NC_008702.1	880162	881298	D	Probable Hypothetical UPF0028 family protein YML059C. TREMBL:Q82SM1: 50% identity, 68% similariry InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin bioF: 8-amino-7-oxononanoate synthase Signal peptide present (SinalP predicted) TMHMM predicted TMH's; Function unclear; hypothetical protein	880162..881298	Azoarcus sp. BH72	4609192
YP_932327.1	CDS	pbpG	NC_008702.1	881699	882541	D	Penicillin-binding protein 5 precursor (PBP-5) (D-alanyl-D-alanine- endopeptidase) (DD-endopeptidase).; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase	881699..882541	Azoarcus sp. BH72	4606590
YP_932328.1	CDS	allR	NC_008702.1	882604	883407	R	Probable negative regulator of allantoin and glyoxylate utilization operons,; High confidence in function and specificity; negative regulator of allantoin and glyoxylate utilization operons	complement(882604..883407)	Azoarcus sp. BH72	4609503
YP_932329.1	CDS	azo0825	NC_008702.1	883506	883727	D	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	883506..883727	Azoarcus sp. BH72	4608305
YP_932330.1	CDS	azo0826	NC_008702.1	883724	884674	D	Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A). PLAYS A CENTRAL ROLE IN ASSIMILATION OF CARBON. IT CONVERTS HYDROXYPYRUVATE TO GLYCERATE AS A KEY STEP IN THE SERINE CYCLE AND MAY ALSO PLAY AN IMPORTANT ROLE IN C2 REACTIONS BY INTERCONVERTING GLYOXYLATE AND GLYCOLATE.; Specificity unclear; glycerate dehydrogenase	883724..884674	Azoarcus sp. BH72	4606591
YP_932331.1	CDS	azo0827	NC_008702.1	884876	886135	D	Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 64% (tremble:BAB1967) Has PF07399:(IPR009978)Protein of unknown function (DUF1504); This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein	884876..886135	Azoarcus sp. BH72	4606592
YP_932332.1	CDS	azo0828	NC_008702.1	886288	887790	D	Putative RNA pseudouridylate synthase. Homology with hits in the database only for the first half of protein. Has PF00849, RNA pseudouridylate synthase; IPR006145, PseudoU_synth; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD P33643, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA. Has SMART;SM00363, S4 RNA-binding domain;IPR002942;The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.; Family membership; pseudouridylate synthase	886288..887790	Azoarcus sp. BH72	4606593
YP_932333.1	CDS	nuoB1	NC_008702.1	887858	888337	R	Conderved hypothetical NADH-quinone oxidoreductase chain B. Homology to nuoB of C. violaceum of 77% (trembl|Q7NUE5). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). Pfam: NADH ubiquinone oxidoreductase, 20 kd no signal peptide no TMHs; Family membership; NADH-quinone oxidoreductase subunit B	complement(887858..888337)	Azoarcus sp. BH72	4606594
YP_932334.1	CDS	azo0830	NC_008702.1	888370	889254	R	Putative AraC-family transcriptional regulator,; Conserved hypothetical protein; AraC family transcriptional regulator	complement(888370..889254)	Azoarcus sp. BH72	4609419
YP_932335.1	CDS	azo0831	NC_008702.1	889332	889562	R	Conserved hypothetical protein. Homology to Daro03000467 of Dechloromonas aromatica of 50% (gi|41725519|ref|ZP_00152277.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(889332..889562)	Azoarcus sp. BH72	4606595
YP_932336.1	CDS	azo0832	NC_008702.1	890060	891259	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8DJ46 (29% identity); TREMBL:Q8YZK5 (29% identity). InterPro (IPR003838): Protein of unknown function DUF214. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family.; Specificity unclear; ABC transporter permease	complement(890060..891259)	Azoarcus sp. BH72	4606596
YP_932337.1	CDS	azo0833	NC_008702.1	891269	892477	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8YZK5 (28% identity); TREMBL:Q8DJ46 (29% identity). Pfam (DUF214): Predicted permease. TMHMM reporting five transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family.; Specificity unclear; ABC transporter permease	complement(891269..892477)	Azoarcus sp. BH72	4606597
YP_932338.1	CDS	azo0834	NC_008702.1	892474	893181	R	Putative efflux transporter for macrolide antibiotics (MacB-family). Acts in conjunction with MacA. Similar to TREMBL:Q82W68 (59% identity); TREMBL:Q8RAL4 (46% identity); SWISSPROT:P75831 (41% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1.122): The Macrolide Exporter (MacB) Family.; Family membership; ABC transporter ATP-binding protein	complement(892474..893181)	Azoarcus sp. BH72	4606598
YP_932339.1	CDS	azo0835	NC_008702.1	893195	894343	R	The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership; membrane fusion protein	complement(893195..894343)	Azoarcus sp. BH72	4606599
YP_932340.1	CDS	glnS	NC_008702.1	894555	896288	R	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase	complement(894555..896288)	Azoarcus sp. BH72	4606600
YP_932341.1	CDS	azo0837	NC_008702.1	896453	896836	D	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB	896453..896836	Azoarcus sp. BH72	4608904
YP_932342.1	CDS	azo0838	NC_008702.1	896956	897630	D	Conserved hypothetical puter membrane protein Homology to cv1891 of c. violaceum of 64% (trembl|Q7NWT8) InterPro: Bacterial outer membrane protein (IPR006664) Pfam: OmpA family signal peptide 2 TMHs; Family membership; outer membrane protein	896956..897630	Azoarcus sp. BH72	4606601
YP_932343.1	CDS	azo0839	NC_008702.1	897685	900981	R	SWI/SNF family helicase Pfam: Helicase conserved C-terminal domain; Specificity unclear; SWI/SNF family helicase	complement(897685..900981)	Azoarcus sp. BH72	4606602
YP_932344.1	CDS	thiC	NC_008702.1	901163	903079	R	required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC	complement(901163..903079)	Azoarcus sp. BH72	4606603
YP_932345.1	CDS	thiD1	NC_008702.1	903169	904023	R	Phosphomethylpyrimidine kinase (EC 2.7.4.7) (HMP-phosphate kinase) (HMP-P kinase). CATALYZES THE PHOSPHORYLATION OF HMP-P TO HMP-PP. TIGRFAM: HMP-P_kinase: phosphomethylpyrimidine kinase; High confidence in function and specificity; phosphomethylpyrimidine kinase	complement(903169..904023)	Azoarcus sp. BH72	4609934
YP_932346.1	CDS	ecaA	NC_008702.1	904277	905893	D	Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase).Involved in the reversible hydration of carbon dioxide. 40% Euk_COanhd.IPR000437; Prok_lipoprot_S.IPR006311;Tat. InterPro: belongs to the eukaryotic-type carbonic anhydrase family. Pfam:PF00194; carb_anhydrase; 1. TIGRFAMs:TIGR01409; TAT_signal_seq; 1. Signal peptide present.; High confidence in function and specificity; putative carbonic anhydrase	904277..905893	Azoarcus sp. BH72	4609935
YP_932347.1	CDS	azo0843	NC_008702.1	905906	907309	R	Conserved hypothetical transcriptional regulator. Homology to rsc0989 of r. solanacearum of 47% (CAD14691). Pfam: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II no signal peptide no TMHs bioF: 8-amino-7-oxononanoate synthase; Specificity unclear; putative transcriptional regulator	complement(905906..907309)	Azoarcus sp. BH72	4608661
YP_932348.1	CDS	azo0844	NC_008702.1	907471	907926	D	Hypothetical secreted protein. No homology to the data base. No domain predicted. No TMHs. Signal peptide.; hypothetical protein	907471..907926	Azoarcus sp. BH72	4606604
YP_932349.1	CDS	azo0845	NC_008702.1	908009	908686	D	Conserved hypothetical transcriptional regulator. Homology to RSc0698 of alstonia solanacearum of 48% (gnl|keqq|rso:RS01603(KEGG)). InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins,tetR family. HTH reporting nucleic acid binding motif. No signal peptide. No TMHs.; Conserved hypothetical protein; putative transcriptional regulator	908009..908686	Azoarcus sp. BH72	4606605
YP_932350.1	CDS	azo0846	NC_008702.1	908683	909771	D	Similar to TREMBL:Q7NR61 (35% identity); TREMBL:Q8XYV3 (33% identity); TREMBL:Q88MQ4 (32% identity). InterPro (IPR006143): Secretion protein HlyD. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family.; Family membership; membrane fusion protein	908683..909771	Azoarcus sp. BH72	4606606
YP_932351.1	CDS	azo0847	NC_008702.1	909768	912986	D	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9A7D5 (35% identity); TREMBL:Q9HXW4 (55% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	909768..912986	Azoarcus sp. BH72	4606607
YP_932352.1	CDS	pcm1	NC_008702.1	913062	913715	D	Putative protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). InterPro: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (IPR000682), SAM binding motif (IPR000051) Tigrfam: pimt: protein-L-isoaspartate O-methyltransfase Pfam: Protein-L-isoaspartate (D-aspartate) O-methyltransferase no signal peptide no TMHs; High confidence in function and specificity; putative protein-L-isoaspartate O-methyltransferase	913062..913715	Azoarcus sp. BH72	4606608
YP_932353.1	CDS	azo0849	NC_008702.1	913724	914047	D	Putative rhodanese-related sulfurtransferase. TIGR:NMB1884. InterPro:IPR001763; Rhodanese-like. InterPro: Rhodanese/cdc25 fold. Pfam:PF00581; Rhodanese; 1.; Function unclear; putative sulfurtransferase	913724..914047	Azoarcus sp. BH72	4609510
YP_932354.1	CDS	tolC	NC_008702.1	914066	915382	D	Putative outer membrane effluxe protein protein. Homology to tolC from E. coli of 33%. The OEP family (outer membreane effluxe protein) allow export of a variety of substrates in Gram negative bacteria. TolC is believed to be a membre af an ABC transporter system for protein secretion without cleavage of a signal sequence. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership; putative outer membrane efflux protein	914066..915382	Azoarcus sp. BH72	4606609
YP_932355.1	CDS	waaA	NC_008702.1	915379	916623	R	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase	complement(915379..916623)	Azoarcus sp. BH72	4609959
YP_932356.1	CDS	wbnF	NC_008702.1	916809	917816	D	Probably involved in the biosynthesis of exopolysaccharides. 68% Epimerase_Dh.IPR008089; Nuc_sugar_epim. Pfam:PF01370; Epimerase; 1.; High confidence in function and specificity; putative nucleotide sugar epimerase	916809..917816	Azoarcus sp. BH72	4610100
YP_932357.1	CDS	apaH	NC_008702.1	917838	918635	D	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase	917838..918635	Azoarcus sp. BH72	4610110
YP_932358.1	CDS	plsC	NC_008702.1	918645	919436	R	Function:-Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:- PLSC_NEIGO Primary accession number :- Q59601 InterPro IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam PF01553; Acyltransferase; 1. Identities = 68/182 (37%) Prediction: Non-secretory protein Signal peptide probability: 0.096 Number of predicted TMHs: 0; Family membership; putative 1-acyl-sn-glycerol-3-phosphate acyltransferase	complement(918645..919436)	Azoarcus sp. BH72	4608324
YP_932359.1	CDS	azo0855	NC_008702.1	919508	920266	R	Conserved hypothetical protein. Homology to cv0660 of C. violaceum of 59% (trembl|Q7P0A7) no domains predicted no singal peptide no TMHs; hypothetical protein	complement(919508..920266)	Azoarcus sp. BH72	4609584
YP_932360.1	CDS	azo0856	NC_008702.1	920383	921654	D	Similar to amylovoran biosynthesis glycosyl transferase amsK (EC 2.-.-.-). INVOLVED IN THE BIOSYNTHESIS OF AMYLOVORAN WHICH FUNCTIONS AS A VIRULENCE FACTOR. Similar to protein annotated as sulfolipid sulfoquinovosyldiacylglycerol biosynthesis proteins.; Family membership; glycosyltransferase	920383..921654	Azoarcus sp. BH72	4606610
YP_932361.1	CDS	azo0857	NC_008702.1	921718	922653	D	38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1.; Specificity unclear; putative carbohydrate kinase	921718..922653	Azoarcus sp. BH72	4606611
YP_932362.1	CDS	slyB	NC_008702.1	922647	923120	D	Outer membrane lipoprotein SlyB. Homology to slyB of E. coli of 32% (sprot|SLYB_ECOLI) no domains predicted signal peptide no TMHs; Family membership; putative outer membrane protein SlyB	922647..923120	Azoarcus sp. BH72	4606612
YP_932363.1	CDS	dgkA	NC_008702.1	923122	923514	R	Probable Diacylglycerol kinase. Homology to dgkA of E. coli of 40% (sprot|KDGL_ECOLI) RECYCLING OF DIACYLGLYCEROL PRODUCED DURING THE TURNOVER OF MEMBRANE PHOSPHOLIPID (BY SIMILARITY). Pfam: prokaryotic diacylglycerol kinase no signal peptide 2 TMHs; High confidence in function and specificity; diacylglycerol kinase	complement(923122..923514)	Azoarcus sp. BH72	4609875
YP_932364.1	CDS	azo0860	NC_008702.1	923623	924912	R	Hypothetical protein. No Domains,Features,Signal Pepetide or TMH reported Present. Most top hits suggest the possibillity of Transmembrane protein, but due to non existance of any TMH's domains it cant be considered as a choice.; Specificity unclear; hypothetical protein	complement(923623..924912)	Azoarcus sp. BH72	4608620
YP_932365.1	CDS	prmA	NC_008702.1	924919	925803	R	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase	complement(924919..925803)	Azoarcus sp. BH72	4606613
YP_932366.1	CDS	accC1	NC_008702.1	925814	927175	R	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit	complement(925814..927175)	Azoarcus sp. BH72	4609631
YP_932367.1	CDS	azo0863	NC_008702.1	927168	927296	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(927168..927296)	Azoarcus sp. BH72	4608256
YP_932368.1	CDS	accB	NC_008702.1	927305	927757	R	Function:-Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP). THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A CARBOXYLASE COMPLEX; FIRST BIOTIN CARBOXYLASE CATALYZES THE CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA. Entry name:-SWISSPROT:BCCP_ECOLI Prim. accession # P02905 InterPro :-IPR001249; AcCoA_biotinCC. IPR001882; Biotin_BS. IPR000089; Biotin_lipoyl. Pfam:- PF00364; Biotin_lipoyl; 1. Number of predicted TMHs: 0 Identity:- 94/157 (59%); High confidence in function and specificity; biotin carboxyl carrier protein of acetyl-CoA carboxylase	complement(927305..927757)	Azoarcus sp. BH72	4606614
YP_932369.1	CDS	aroQ	NC_008702.1	927813	928310	R	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase	complement(927813..928310)	Azoarcus sp. BH72	4608255
YP_932370.1	CDS	azo0866	NC_008702.1	928372	928908	R	Hypothetical thioredoxin. Homology with BPP3919 of B. parapertussis of 38%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. Tigrfam: dsbE: periplasmic protein thiol:disulfi signal peptide probable 1 TMHs; Family membership; putative thioredoxin	complement(928372..928908)	Azoarcus sp. BH72	4608349
YP_932371.1	CDS	azo0867	NC_008702.1	928905	929594	R	Conserved hypothetical protein, 39% identity to TrEMBL;Q8XVP7; Signal Peptide present. Coils2 program reporting presence of coiled coil. No TMH present. TIGR00004: endoribonuclease L-PSP putat; hypothetical protein	complement(928905..929594)	Azoarcus sp. BH72	4606615
YP_932372.1	CDS	mpl	NC_008702.1	929650	930996	D	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso- diaminopimelate ligase (EC 6.3.2.-) (Murein peptide ligase). REUTILIZES THE INTACT TRIPEPTIDE L-ALANYL-GAMMA-D- GLUTAMYL-MESO-DIAMINOPIMELATE BY LINKING IT TO UDP-N-ACETYLMURAMIC ACID. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity; UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	929650..930996	Azoarcus sp. BH72	4606616
YP_932373.1	CDS	azo0869	NC_008702.1	931018	931668	R	Conserved hypothetical secreted protein. Homology to rsc3264 of R. solanacearum (trembl|Q8XUC7). Smart: Bacterial OsmY and nodulation domain (BON) The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins; outside of this group the distribution is more disparate. signal peptide TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(931018..931668)	Azoarcus sp. BH72	4609267
YP_932374.1	CDS	gmhA	NC_008702.1	931665	932258	R	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase	complement(931665..932258)	Azoarcus sp. BH72	4606617
YP_932375.1	CDS	azo0871	NC_008702.1	932374	932787	R	Conserved hypothetical protein. Homology to pa4424 of P. aeruginosa of 44% (pir|H83091). Pfam: Uncharacterised protein family UPF0102 (PF02021). Interpro: Protein of unkown function UPF0102 (IPR003509). no signal peptide. no TMHs.; hypothetical protein	complement(932374..932787)	Azoarcus sp. BH72	4608927
YP_932376.1	CDS	azo0872	NC_008702.1	932786	933673	D	Conserved hypothetical protein. Homology to pp1326 of P. putida of 56% ((AAN66950). InterPro: Uncharacterized protein family UPF0011 (IPR008189) TIGR00096: conserved hypothetical protein Pfam: Tetropyrrole (Crrin/Porphyrin) methyltransferase no signal peptide no TMHs; hypothetical protein	932786..933673	Azoarcus sp. BH72	4606618
YP_932377.1	CDS	pyrC	NC_008702.1	933728	934762	D	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase	933728..934762	Azoarcus sp. BH72	4606619
YP_932378.1	CDS	azo0874	NC_008702.1	934759	935190	D	Conserved hypothetical secreted protein. Homology to Daro03003273 of Dechloromonas aromatica of 35% (gi|41723286|ref|ZP_00150229.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	934759..935190	Azoarcus sp. BH72	4609669
YP_932379.1	CDS	mraZ	NC_008702.1	935993	936436	D	MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ	935993..936436	Azoarcus sp. BH72	4606620
YP_932380.1	CDS	mraW	NC_008702.1	936433	937371	D	S-adenosyl-methyltransferase mraW (EC 2.1.1.-). Exhibits a S-adenosyl-dependent methyltransferase activity (By similarity). TIGR00006: conserved hypothetical prote; High confidence in function and specificity; S-adenosyl-methyltransferase MraW	936433..937371	Azoarcus sp. BH72	4609270
YP_932381.1	CDS	FtsL	NC_008702.1	937368	937631	D	Putative cell division protein FtsL. Homology to ftsL of E. coli of 32% (sprot|FTSL_ECOLI). Protein involved in cell division and cell growth. May play some role in coupling cell division and peptidoglycan physiology. Pfam: Cell division protein FtsL signal peptide no TMHs; Family membership; putative cell division protein FtsL	937368..937631	Azoarcus sp. BH72	4609268
YP_932382.1	CDS	FtsI	NC_008702.1	937628	939388	D	Probable peptidoglycan glycosyltransferase. Homology to ftsI of E. coli of 43% (sprot|FTSI_ECOLI) Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates. InterPro: Penicillin binding protein transpeptidase domain (IPR001460) Pfam: Penicillin-binding protein dimerisation domain; Penicillin binding proetin transpeptidas domain signal peptide no TMHs; High confidence in function and specificity; peptidoglycan glycosyltransferase	937628..939388	Azoarcus sp. BH72	4608838
YP_932383.1	CDS	murE	NC_008702.1	939385	940890	D	Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase Homology to murE of E. coli of 40% (sprot|MURE_ECOLI) Cell wall formation. Diaminopimelic acid adding enzyme (By similarity). Pfam: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase no signal peptide no TMHs; High confidence in function and specificity; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase	939385..940890	Azoarcus sp. BH72	4608835
YP_932384.1	CDS	murF	NC_008702.1	940863	942299	D	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10) (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme). Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity). InterPro: Cytoplasmic peptidoglycan synthetases N-terminal mobB: molybdopterin-guanine dinucleot; High confidence in function and specificity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase	940863..942299	Azoarcus sp. BH72	4609291
YP_932385.1	CDS	mraY	NC_008702.1	942301	943389	D	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase	942301..943389	Azoarcus sp. BH72	4609292
YP_932386.1	CDS	murD	NC_008702.1	943386	944804	D	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase	943386..944804	Azoarcus sp. BH72	4609269
YP_932387.1	CDS	FtsW	NC_008702.1	944801	946033	D	This is a septum-peptidoglycan biosynthetic protein involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division.; High confidence in function and specificity; cell division protein FtsW	944801..946033	Azoarcus sp. BH72	4609290
YP_932388.1	CDS	murG	NC_008702.1	946030	947100	D	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase	946030..947100	Azoarcus sp. BH72	4608840
YP_932389.1	CDS	murC	NC_008702.1	947097	948500	D	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase	947097..948500	Azoarcus sp. BH72	4609293
YP_932390.1	CDS	ddl	NC_008702.1	948497	949411	D	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase	948497..949411	Azoarcus sp. BH72	4609289
YP_932391.1	CDS	FtsQ	NC_008702.1	949404	950234	D	Putative cell division protein FtsQ. Homology to ftsQ of E. coli of 23% (Sprot:FTSQ_ECOLI) This protein may be involved in septum formation. Pfam: Cell division protein FtsQ no signal peptide 1 TMHs; Family membership; putative cell division protein FtsQ	949404..950234	Azoarcus sp. BH72	4608613
YP_932392.1	CDS	FtsA	NC_008702.1	950231	951460	D	This protein may be involved in anomalous filament growth. May be a component of the septum. It may interact with ftsZ. InterPro: Cell division protein FtsA; High confidence in function and specificity; cell division protein FtsA	950231..951460	Azoarcus sp. BH72	4608839
YP_932393.1	CDS	FtsZ	NC_008702.1	951602	952744	D	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ	951602..952744	Azoarcus sp. BH72	4608832
YP_932394.1	CDS	lpxC	NC_008702.1	952910	953833	D	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase	952910..953833	Azoarcus sp. BH72	4608843
YP_932395.1	CDS	azo0891	NC_008702.1	953868	954056	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 1 TMH; hypothetical protein	953868..954056	Azoarcus sp. BH72	4609176
YP_932396.1	CDS	azo0892	NC_008702.1	954061	954489	R	Conserved hypothetical protein. Homology to CV4285 of C.violaceum of 32% (tremble:Q7NQ55). No domains predicted. No TMHs No signal peptide.; hypothetical protein	complement(954061..954489)	Azoarcus sp. BH72	4606621
YP_932397.1	CDS	secA	NC_008702.1	954595	957324	D	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA	954595..957324	Azoarcus sp. BH72	4606622
YP_932398.1	CDS	azo0894	NC_008702.1	957401	958882	D	GAF-domain containing protein,; Conserved hypothetical protein; GAF-domain-containing protein	957401..958882	Azoarcus sp. BH72	4609857
YP_932399.1	CDS	argJ	NC_008702.1	958968	960209	D	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase	958968..960209	Azoarcus sp. BH72	4606623
YP_932400.1	CDS	azo0896	NC_008702.1	960324	961154	D	Putative phosphoprotein phosphatase,; Conserved hypothetical protein; putative phosphoprotein phosphatase	960324..961154	Azoarcus sp. BH72	4608338
YP_932401.1	CDS	azo0897	NC_008702.1	961167	962186	D	Hypothetical secreted protein. Homology to pp3428 of P. putida of 26% (tremble:Q88HD2). Domain structure: 111 aa - 157 aa LysM; 232 aa - 313 aa TRP. Pfam: LysM domain; TRP. signal peptide. no TMHs; hypothetical protein	961167..962186	Azoarcus sp. BH72	4606624
YP_932402.1	CDS	azo0898	NC_008702.1	962191	963855	R	Putative serine/threonine protein kinase,; Family membership; putative serine/threonine protein kinase	complement(962191..963855)	Azoarcus sp. BH72	4606625
YP_932403.1	CDS	azo0899	NC_008702.1	963863	964384	R	Hypothetical membrane protein. No good homology to a protein of similar size of the data bank. Pfam: FHA domain (PF00498). The forkhead-associated (FHA) domain is a putative nuclear signalling domain found in a variety of otherwise unrelated proteins. The FHA domain comprise approximately 55 to 75 amino acids and contains three highly conserved blocks separated by divergent spacer regions.To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not archaeal genomes. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins,transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes - DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples. Interpro: Forkhead-associated (IPR000253). no signal peptide. 1 TMHs; hypothetical protein	complement(963863..964384)	Azoarcus sp. BH72	4606626
YP_932404.1	CDS	apaG	NC_008702.1	964488	964871	R	protein associated with Co2+ and Mg2+ efflux; ApaG protein	complement(964488..964871)	Azoarcus sp. BH72	4606627
YP_932405.1	CDS	purB	NC_008702.1	965057	966433	D	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase	965057..966433	Azoarcus sp. BH72	4608323
YP_932406.1	CDS	azo0902	NC_008702.1	966512	966829	D	Conserved hypothetical protein. Homology to RS03757 of R.solanacearum of 44% (tremble:Q8XS71). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	966512..966829	Azoarcus sp. BH72	4609655
YP_932407.1	CDS	secF	NC_008702.1	966923	967855	R	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF	complement(966923..967855)	Azoarcus sp. BH72	4606628
YP_932408.1	CDS	secD	NC_008702.1	967876	969750	R	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD	complement(967876..969750)	Azoarcus sp. BH72	4609861
YP_932409.1	CDS	yajC	NC_008702.1	969851	970180	R	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC	complement(969851..970180)	Azoarcus sp. BH72	4609859
YP_932410.1	CDS	azo0906	NC_008702.1	970362	971201	D	Conserved hypothetical signal transduction protein. Homology to Daro03002984 of Dechloromonas aromatica of 39% (gi|53729872|ref|ZP_00150342.2|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs; Conserved hypothetical protein; putative signal transduction protein	970362..971201	Azoarcus sp. BH72	4610141
YP_932411.1	CDS	tgt	NC_008702.1	971214	972326	R	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase	complement(971214..972326)	Azoarcus sp. BH72	4606629
YP_932412.1	CDS	queA	NC_008702.1	972316	973353	R	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase	complement(972316..973353)	Azoarcus sp. BH72	4609932
YP_932413.1	CDS	nhaR	NC_008702.1	973554	974405	R	Transcriptional activator protein nhaR (Na+/H+ antiporter regulatory protein). Plays a role in the positive regulation of nhaA. Similar to SWISSPROT: sprot|NHAR_ECOLI (34% Escherichia coli, and Shigella flexneri, transcriptional activator protein NhaR (na+/h+ antiporter regulatory protein)) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family.; High confidence in function and specificity; LysR family transcriptional regulator	complement(973554..974405)	Azoarcus sp. BH72	4610002
YP_932414.1	CDS	azo0910	NC_008702.1	974584	974925	D	Conserved hypothetical protein. Homology to ebD81 Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebD81(KEGG)). No domains predicted. No signal peptid. No TMHs; hypothetical protein	974584..974925	Azoarcus sp. BH72	4609355
YP_932415.1	CDS	yccA	NC_008702.1	974987	975652	D	Hypothetical protein PA2604. pir:D85624: 57% identity.73% similarity SIMILARITY:Belongs to the BI1 family. InterPro:Uncharacterized protein family UPF0005 IPR006213; Bax_inhbtr1. IPR006214; UPF0005. Pfam:ZIP: Zinc transporter Probable glutamatereceptor Signal peptide present (SignalP predicted) and transmembrane helices 7 (TMHMM predicted) Pfam:PF01027; UPF0005; InterPro: Uncharacterized protein family UPF0005 2_A_01_02: Multidrug resistance protein; Specificity unclear; carrier/transport protein	974987..975652	Azoarcus sp. BH72	4606630
YP_932416.1	CDS	rosB	NC_008702.1	975796	977517	D	Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12.; High confidence in function and specificity; putative potassium/proton antiporter	975796..977517	Azoarcus sp. BH72	4610155
YP_932417.1	CDS	ytfL2	NC_008702.1	977524	978858	R	Hypothetical protein sll0260. CBS domains are found in the intracellular regions of a number of different integral membrane proteins. Two CBS domains are found in intracellular loops of several voltage gated chloride channels. A family of magnesium transporters also contain CBS domains. TREMBL:Q8KEZ1: 61% identity, 74% similarity InterPro: Domain of unknown function DUF21 InterPro:IPR002550; CBS. IPR000644: CBS_domain. IPR005170: CorC_transpt-asc. Pfam: PF00571; CBS; 2. PF03471: CorC_HlyC; 1. PF01595: DUF21; gntP: gluconate transporter Signal peptide present Transmembrane helices 3; Specificity unclear; hemolysin	complement(977524..978858)	Azoarcus sp. BH72	4609757
YP_932418.1	CDS	terC	NC_008702.1	979395	980357	D	Tellurium resistance protein terC. Could conceivably alter the intracellular level of tellurium in a manner leading to resistance. Alternatively its presence in the membrane may provide a barrier to entry of the tellurium ions.32% TerC. Pfam: PF03741; TerC; 1. TMHelix:9.; High confidence in function and specificity; putative tellurium resistance protein	979395..980357	Azoarcus sp. BH72	4610198
YP_932419.1	CDS	accA	NC_008702.1	980435	981400	D	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha	980435..981400	Azoarcus sp. BH72	4609927
YP_932420.1	CDS	tilS	NC_008702.1	981412	982758	D	Putative tRNA(Ile)-lysidine synthetase. Homology to tils of E.coli of 34% (gnl|keqq|eco:b0188(KEGG)). Pfam: PP-loop family. Tigrfam: tRNA(Ile)-lysidine synthetase. The only examples in which the wobble position of a tRNA must discriminate between G and A of mRNA are AUA (Ile) vs. AUG (Met) and UGA (stop) vs. UGG (Trp). In all bacteria, the wobble position of the tRNA(Ile) recognizing AUA is lysidine, a lysine derivative of cytidine. This family describes a protein domain found, apparently, in all bacteria in a single copy. Eukaryotic sequences appear to be organellar. The domain archictecture of this protein family is variable; some, including characterized proteins of E. coli and B. subtilis known to be tRNA(Ile)-lysidine synthetase, include a conserved 50-residue domain that many other members lack. This protein belongs to the ATP-binding PP-loop family ( PF01171). It appears in the literature and protein databases as TilS, YacA, and putative cell cycle protein MesJ (a misnomer). No signal peptide. No TMHs.; Family membership; putative tRNA(Ile)-lysidine synthetase	981412..982758	Azoarcus sp. BH72	4608254
YP_932421.1	CDS	azo0917	NC_008702.1	982714	983319	R	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity; two-component response regulator	complement(982714..983319)	Azoarcus sp. BH72	4609948
YP_932422.1	CDS	dctS	NC_008702.1	983320	985311	R	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity; two-component sensor kinase	complement(983320..985311)	Azoarcus sp. BH72	4606631
YP_932423.1	CDS	dctP2	NC_008702.1	985540	986544	D	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 70% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present. TMhelix:1; High confidence in function and specificity; c4-dicarboxylate-binding periplasmic protein	985540..986544	Azoarcus sp. BH72	4608612
YP_932424.1	CDS	dctQ2	NC_008702.1	986612	987310	D	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 45% DctQ. Pfam:PF04290; DctQ; 1. TMhelix:4.; High confidence in function and specificity; putative TRAP-type C4-dicarboxylate transport system small permease	986612..987310	Azoarcus sp. BH72	4608603
YP_932425.1	CDS	dctM2	NC_008702.1	987325	988611	D	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 60% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMhelix:13. Signal peptide: present.; High confidence in function and specificity; putative TRAP-type C4-dicarboxylate transport system large permease	987325..988611	Azoarcus sp. BH72	4608609
YP_932426.1	CDS	dedA	NC_008702.1	988762	989409	D	DedA family protein, 57% identity(75% similarity) to TrEMBL;Q88QF4. TrEMBl;Q889M5(57% identity). SwissProt;P09548(55% identity) Has PF00597, DedA family;IPR000252;This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; High confidence in function and specificity; DedA protein	988762..989409	Azoarcus sp. BH72	4608598
YP_932427.1	CDS	ndk	NC_008702.1	989496	989921	D	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase	989496..989921	Azoarcus sp. BH72	4608615
YP_932428.1	CDS	azo0924	NC_008702.1	990009	991136	D	Hypothetical protein yfgB. putative fe-s-cluster redox enzyme TREMBL:Q7NS85: 70% identity; 80% similarity. InterPro:IPR004383; Cons_hypoth48. IPR007197: Radical_SAM. Pfam:PF04055; Radical_SAM; No signal peptide. No transmembrane helices. TIGR00048: conserved hypothetical prote; Function unclear; hypothetical protein	990009..991136	Azoarcus sp. BH72	4609350
YP_932429.1	CDS	pilF	NC_008702.1	991136	991951	D	Type 4 pilus biogenesis protein,; Function unclear; putative type 4 pilus biogenesis protein	991136..991951	Azoarcus sp. BH72	4606632
YP_932430.1	CDS	azo0926	NC_008702.1	991948	992856	D	Transcriptional regulator , 36% identity to TrEMBL;Q88PJ8. Weak homology with other proteins spanning entire length. Prosite,PS50943; HTH_CROC1; The cro/C1-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 50-60 residues present in transcriptional regulators. The domain is named after the transcriptional repressors cro and C1 of temperate bacteriophages 434 and lambda, respectively.; Specificity unclear; transcriptional regulator	991948..992856	Azoarcus sp. BH72	4609560
YP_932431.1	CDS	ispG	NC_008702.1	992856	994103	D	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase	992856..994103	Azoarcus sp. BH72	4606633
YP_932432.1	CDS	hisS	NC_008702.1	994138	995439	D	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase	994138..995439	Azoarcus sp. BH72	4608868
YP_932433.1	CDS	azo0929	NC_008702.1	995426	996070	D	Putative membrane protein, 32% identity to TrEMBL;Q7WHN2. Signal Peptide present.; Specificity unclear; hypothetical protein	995426..996070	Azoarcus sp. BH72	4609009
YP_932434.1	CDS	azo0930	NC_008702.1	996074	997216	D	PQQ enzyme repeat protein, 40% identical(60% similarity)to TrEMBL;Q82XU7. Signal Peptide present. Has 6 copies SMART;SM00564, PQQ, beta-propeller repeat;IPR002372; Beta-propeller repeat occurrs in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.; Specificity unclear; hypothetical protein	996074..997216	Azoarcus sp. BH72	4606634
YP_932435.1	CDS	engA	NC_008702.1	997232	998560	D	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA	997232..998560	Azoarcus sp. BH72	4606635
YP_932436.1	CDS	hfq	NC_008702.1	998667	998909	D	Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq	998667..998909	Azoarcus sp. BH72	4608668
YP_932437.1	CDS	hflX1	NC_008702.1	998991	1000130	D	GTP-binding protein hflX. trembl:Q7NS94: 66% identity; 78% similarity. InterPro:IPR006073; GTP1_OBG. These proteins contain GTP-binding motifs and are GTP1OBG Pfam:MMR_HSR1:GTPase of unknown function thdF: tRNA modification GTPase TrmE No Signal peptide present (SignalP predicted) Absence of transmembrane helices (TMHMM predicted); Family membership; GTP-binding subunit of protease specific for phage lambda	998991..1000130	Azoarcus sp. BH72	4608996
YP_932438.1	CDS	hflK	NC_008702.1	1000148	1001389	D	Putative HflK protein. Homology to hflK of E. coli of 40% (sprot|HFLK_ECOLI). hflc and hflk govern the stability of phage lambda cii protein and have been proposed to encode or regulate a cii- specific protease. Pfam: SPFH domain/band 7 family no signal peptide 1 TMH; Family membership; putative Hflk protein	1000148..1001389	Azoarcus sp. BH72	4608994
YP_932439.1	CDS	hflC	NC_008702.1	1001389	1002270	D	Conserved hypothetical protein. Homology to hflC of E. coli of 37% (sprot|HFLC_ECOLI). hflc and hflk govern the stability of phage lambda cii protein and have been proposed to encode or regulate a cii- specific protease. Pfam: SPFH domain/ Band 7 family signal peptide; Family membership; hypothetical protein	1001389..1002270	Azoarcus sp. BH72	4608993
YP_932440.1	CDS	azo0936	NC_008702.1	1002278	1002463	D	Conserved hypothetical membrane protein. Homology to NE1283 of Nitrosomonas europaea of 60% (trembl|Q82V27). No domains predicted. Signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	1002278..1002463	Azoarcus sp. BH72	4608992
YP_932441.1	CDS	hisZ	NC_008702.1	1002471	1003625	D	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit	1002471..1003625	Azoarcus sp. BH72	4606636
YP_932442.1	CDS	purA	NC_008702.1	1003629	1004939	D	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase	1003629..1004939	Azoarcus sp. BH72	4609010
YP_932443.1	CDS	vacB	NC_008702.1	1005674	1008655	D	Ribonuclease R (EC 3.1.-.-) (RNase R) (VacB protein homolog). 3-exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A) poly(U) and ribosomal RNAs. Similar to SWISSPROT: sprot|RNR_ECOLI (38% Escherichia coli, ribonuclease R; RNase R / VacB protein) InterPro: IPR004476 3_prime_RNase. IPR003029 RNA binding S1. Pfam: PF00773 RNB-like protein. TIGRFAM: TIGR00358 VacB and RNase II family 3'-5' exoribonucleases.; High confidence in function and specificity; exoribonuclease II	1005674..1008655	Azoarcus sp. BH72	4610004
YP_932444.1	CDS	azo0940	NC_008702.1	1008648	1009412	D	Specificity unclear; tRNA/rRNA methyltransferase	1008648..1009412	Azoarcus sp. BH72	4610087
YP_932445.1	CDS	azo0941	NC_008702.1	1009579	1010880	D	Probable nitrate regulatory protein,; High confidence in function and specificity; nitrate regulatory protein	1009579..1010880	Azoarcus sp. BH72	4606637
YP_932446.1	CDS	nasF	NC_008702.1	1011215	1012474	D	Part of the ABC transporter complex NasFED involved in nitrate import. 59% Similar to the putative periplasmic-binding protein NasF in Klebsiella oxytoca. TREMBL:Q48466 InterPro:IPR010067; SsuA_fam.IPR006311; Tat. TIGRFAMs:TIGR01728; SsuA_fam; 1.TIGR01409; TAT_signal_seq; 1. Signal peptide present.; High confidence in function and specificity; nitrate transport system periplasmic-binding protein	1011215..1012474	Azoarcus sp. BH72	4606638
YP_932447.1	CDS	nasE	NC_008702.1	1012491	1013423	D	Nitrate transport permease nasE. 41% Similar to the nitrate permease, nrtB in Synechococcus sp.Part of the ABC transporter complex nrtBCD involved in nitrate import.Probably responsible for the translocation of the substrate across the membrane. SWISSPROT:NRTB_SYNP7.P38044. InterPro:IPR000515; BPD_transp.IPR005889; NtrB. Pfam:PF00528; BPD_transp; 1. TIGRFAMs:TIGR01183; ntrB; 1. TMHelix: 4.; High confidence in function and specificity; putative nitrate transport system permease	1012491..1013423	Azoarcus sp. BH72	4609345
YP_932448.1	CDS	nasD	NC_008702.1	1013436	1014230	D	Part of the ABC transporter complex nasFED involved in nitrate import. 64% Similar to the nitrate transport membrane protein, nasD in Klebsella oxytoca. Probably responsible for energy coupling to the transport system. SWISSPROT:NASD_KLEOX.P39459. InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter.IPR005890; NtrCD. Pfam:PF00005; ABC_tran; 1. TIGRFAMs:TIGR01184; ntrCD; 1.; High confidence in function and specificity; putative nitrate transport system ATP-binding protein	1013436..1014230	Azoarcus sp. BH72	4609344
YP_932449.1	CDS	cobA1	NC_008702.1	1014601	1015365	D	Uroporphyrin-III C-methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). CATALYZES BOTH METHYLATIONS AT C-2 AND C-7 OF UROGEN III LEADING TO PRECORRIN-1 AND PRECORRIN-2; THEIR OXIDATIVE ESTERIFICATION GIVES RESPECTIVELY FACTOR I OCTAMETHYL ESTER AND SIROHYDROCHLORIN (BY SIMILARITY). dph5: diphthine synthase; High confidence in function and specificity; uroporphyrin-III C-methyltransferase	1014601..1015365	Azoarcus sp. BH72	4609343
YP_932450.1	CDS	nasC	NC_008702.1	1015380	1016627	D	Putative nitrate reducatse small subunit. Homology to nasC of K. oxytoca of 38% (trembl|Q48467). NasC probably mediates electron transfer from NADH to NasA, the nitrate reductase. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs; Family membership; putative nitrate reductase small subunit	1015380..1016627	Azoarcus sp. BH72	4608497
YP_932451.1	CDS	nasA	NC_008702.1	1016664	1019438	D	Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity; nitrate reductase	1016664..1019438	Azoarcus sp. BH72	4609342
YP_932452.1	CDS	azo0948	NC_008702.1	1019477	1020664	D	Putative methyl-accepting chemotaxis protein,; Specificity unclear; putative methyl-accepting chemotaxis protein	1019477..1020664	Azoarcus sp. BH72	4609341
YP_932453.1	CDS	azo0949	NC_008702.1	1020736	1021629	D	Conserved hypothetical secreted protein. Homology to Daro03002329 of Dechloromonas aromatica of 40% (gi|53730441|ref|ZP_00348795.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	1020736..1021629	Azoarcus sp. BH72	4606639
YP_932454.1	CDS	azo0950	NC_008702.1	1021632	1023464	D	GGEF/EAL/PAS/PAC-domain containing protein; GGEF/EAL/PAS/PAC-domain-containing protein	1021632..1023464	Azoarcus sp. BH72	4606640
YP_932455.1	CDS	azo0951	NC_008702.1	1023516	1023875	D	50%Cupin.IPR007113; Cupin_sup. Pfam:PF00190; Cupin; 1. 28%; phosphomannose protein	1023516..1023875	Azoarcus sp. BH72	4606641
YP_932456.1	CDS	azo0952	NC_008702.1	1024028	1024933	D	Conserved hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q7WXG4 Signal Peptide Present.TMH not Present. Has PF04471:Restriction endonuclease;(IPR007560:Mrr_cat):Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. PF01396:Topoisomerase DNA binding C4 zinc finger;(IPR000380 DNA_tpisomrase):Prokaryotic topoisomerase I , otherwise known as relaxing enzyme,untwisting enzyme or swivelase, catalyses the ATP-independent breakage of single- stranded DNA, followed by passage and rejoining of another single-stranded DNA region [4]. This reaction brings about the conversion of one topological isomer of DNA into another: e.g.,relaxation of superhelical turns; interconversion of simple and knotted rings of single-stranded DNA; and intertwisting of single-stranded rings of complementary sequences.; Family membership; hypothetical protein	1024028..1024933	Azoarcus sp. BH72	4606642
YP_932457.1	CDS	nfsA	NC_008702.1	1024961	1025785	R	Putative oxygen-insensitive NADPH nitroreductase. Homology to snrA of S. typhimurium of 37% (sprot|NFSA_SALTY) REDUCTION OF NITROAROMATIC COMPOUNDS USING NADH. REDUCES NITROFURAZONE BY A PING-PONG BI-BI MECHANISM POSSIBLY TO GENERATE A TWO-ELECTRON TRANSFER PRODUCT. MAJOR COMPONENT OF THE OXYGEN- INSENSITIVE NITROREDUCTASE ACTIVITY IN E.COLI. Pfam: Nitroreductase family no signal peptide no TMHs; Family membership; putative oxygen-insentive NADPH nitroreductase	complement(1024961..1025785)	Azoarcus sp. BH72	4606643
YP_932458.1	CDS	isiB	NC_008702.1	1025891	1026424	R	Probable flavodoxin. Homology to isiB of Synechococcus sp. of 45% (pir|B47673) Flavodoxins are electron-transfer proteins that function in various electron transport systems. Flavodoxins bind one FMN molecule, which serves as a redox-active prosthetic group and are functionally interchangeable with ferredoxins. Pfam: Flavodoxin no signal peptide no TMHs; High confidence in function and specificity; flavodoxin	complement(1025891..1026424)	Azoarcus sp. BH72	4609354
YP_932459.1	CDS	gufA	NC_008702.1	1026770	1027678	R	Putative GufA protein. 31% Zn_transpt_Zip.InterPro: ZIP Zinc transporter Pfam: PF02535; Zip; 1. TMHelix: 9. Signal peptide present.; Specificity unclear; putative cation transporter protein	complement(1026770..1027678)	Azoarcus sp. BH72	4609092
YP_932460.1	CDS	cfa1	NC_008702.1	1027781	1029013	R	catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase	complement(1027781..1029013)	Azoarcus sp. BH72	4608964
YP_932461.1	CDS	dnaX	NC_008702.1	1029315	1031303	D	DNA polymerase III subunit tau (EC 2.7.7.7) [Contains: DNA polymerase III subunit gamma]. The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA. InterPro: AAA-protein (ATPases associated with various cellular activities); High confidence in function and specificity; DNA polymerase III subunit tau	1029315..1031303	Azoarcus sp. BH72	4608462
YP_932462.1	CDS	azo0958	NC_008702.1	1031349	1031678	D	conserved hypothetical protein Pfam: Uncharacterized BCR, YbaB family; hypothetical protein	1031349..1031678	Azoarcus sp. BH72	4608640
YP_932463.1	CDS	recR	NC_008702.1	1031759	1032358	D	involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR	1031759..1032358	Azoarcus sp. BH72	4606644
YP_932464.1	CDS	petA1	NC_008702.1	1032540	1033133	D	Probable ubiquinol-cytochrome c reductase iron-sulfur protein (Rieske iron-sulfur protein) (RISP). Homology to petA of R. gelantinosus of 63% (trembl|Q93SY7). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Pfam: Rieske [2Fe-2S] domain singal peptide no TMHs; High confidence in function and specificity; ubiquinol-cytochrome c reductase iron-sulfur protein	1032540..1033133	Azoarcus sp. BH72	4606645
YP_932465.1	CDS	petB	NC_008702.1	1033137	1034405	D	Ubiquinol-cytochrome c reductase cytochrome b protein. Homology to petB of R. gelatinosus of 72% (trembl|Q93SY6). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). Pfam: Cytochrome b (N-terminal)/b6/petB; cytochrome b (C-terminal)/b6/petD no signal peptide 10 TMHs; High confidence in function and specificity; ubiquinol-cytochrome c reductase cytochrome b protein	1033137..1034405	Azoarcus sp. BH72	4609524
YP_932466.1	CDS	petC	NC_008702.1	1034402	1035157	D	Conserved hypothetical ubiquinol-cytochrome c reductase cytochrome c1 protein. Homology to petC of R. solanacearum of 52% (trembl|Q8XVA4). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. InterPro: Cytochrome c1 (IPR002326) Pfam: Cytochrome_c1 signal peptide 1 TMH; Conserved hypothetical protein; putative ubiquinol-cytochrome c reductase cytochrome c1 protein	1034402..1035157	Azoarcus sp. BH72	4609526
YP_932467.1	CDS	sspA2	NC_008702.1	1035265	1035861	D	Probable Stringent starvation protein A. Homology to sspA of E. coli of 43% (sprot|SSPA_ECOLI). FORMS AN EQUIMOLAR COMPLEX WITH THE RNA POLYMERASE HOLOENZYME (RNAP) BUT NOT WITH THE CORE ENZYME. IT IS SYNTHESIZED PREDOMINANTLY WHEN CELLS ARE EXPOSED TO AMINO ACID STARVATION AT WHICH TIME IT ACCOUNTS FOR OVER 50% OF THE TOTAL PROTEIN SYNTHESIZED. Pfam: Glutatione S-transferase,N-terminale domaine no TMHs; Family membership; stringent starvation protein A	1035265..1035861	Azoarcus sp. BH72	4609527
YP_932468.1	CDS	sspB	NC_008702.1	1035915	1036355	D	Putative stringent starvation protein B. Homology to sspB of E. coli of 38% (sprot|SSPB_ECOLI) Seems to act in concert with sspA in the regulation of several proteins during exponential and stationary-phase growth. The exact function of sspB is not yet known. Pfam: Stringent starvation protein B no signal peptide no TMHs; ClpXP protease specificity-enhancing factor	1035915..1036355	Azoarcus sp. BH72	4609896
YP_932469.1	CDS	azo0965	NC_008702.1	1036339	1037562	R	InterPro: Glycosyl transferases group 1; Family membership; glycosyltransferase	complement(1036339..1037562)	Azoarcus sp. BH72	4609897
YP_932470.1	CDS	azo0966	NC_008702.1	1037729	1038217	D	Hemerythrin-like protein, 49% Identity to SProt;Q8Y1B3. Has PF01814, Hemerythrin HHE cation binding domain; IPR002063, Hemerythrin; Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor P80255 binds Cadmium so as to protect the organism from toxicity . However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96 is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.; cation-binding hemerythrin HHE family protein	1037729..1038217	Azoarcus sp. BH72	4606646
YP_932471.1	CDS	dadA1	NC_008702.1	1038235	1039485	R	The L-alanine catabolic pathway proceeds in two steps: racemization of the L-isomer to D-alanine by alanine racemase and oxidative deamination of D-alanine to pyruvate and ammonia by D- amino acid dehydrogenase. Similar to trembl|Q7NRT8 (52%) and to sprot|DADA_ECOLI (40%). Pfam (PF01266): D-amino acid oxidase; Specificity unclear; D-amino acid dehydrogenase small subunit	complement(1038235..1039485)	Azoarcus sp. BH72	4606647
YP_932472.1	CDS	cbbF	NC_008702.1	1039663	1040664	D	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase	1039663..1040664	Azoarcus sp. BH72	4608578
YP_932473.1	CDS	azo0969	NC_008702.1	1040676	1042403	D	conserved hypothetical outer membrane protein. Homology to ne0930 of N. europaea of 44% (trembl|Q82VX0) Pfam: Bacterial surface protein signal peptide no TMHs; Family membership; outer membrane protein	1040676..1042403	Azoarcus sp. BH72	4608421
YP_932474.1	CDS	azo0970	NC_008702.1	1042491	1043462	D	Conserved hypothetical secreted protein. Homology to bb3356 of B. bronchiseptica of 83% (trembl|Q7WH54). Pfam: DUF534 This is a family of putative secreted proteins of unknown function. signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	1042491..1043462	Azoarcus sp. BH72	4606648
YP_932475.1	CDS	azo0971	NC_008702.1	1043538	1044428	D	Conserved hypothetical ABC transporter permease. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851) Pfam: Branched-chain amino acid transport system/permease component no signal peptide 8 TMHs 2A78: Carboxylate/Amino Acid/Amine Tran; Specificity unclear; ABC transporter permease	1043538..1044428	Azoarcus sp. BH72	4606649
YP_932476.1	CDS	azo0972	NC_008702.1	1044430	1045224	D	Thiamine transport ATP-binding protein thiQ. PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM TBPA-THIPQ FOR THIAMINE AND TPP. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q7WH56: 84% identity, 92% similarity Description:putative abc-transporter atp-binding component InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; ProDom PD000006; ABC_transporter; 1. SMART SM00382; AAA recf: DNA replication and repair protein NO transmembrane helices; Function unclear; ABC transporter ATP-binding protein	1044430..1045224	Azoarcus sp. BH72	4606650
YP_932477.1	CDS	groES1	NC_008702.1	1045436	1045726	D	Chaperonin GroES. Homolgy to groES of B. japonicum of 61% (sprot|CH11_BRAJA) Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. InterPro: Chaperonins cpn10 (10 Kd subunit)(IPR001476) Pfam: Chaperonin 10 kd subunit no signal peptide no TMH; High confidence in function and specificity; chaperonin GroES	1045436..1045726	Azoarcus sp. BH72	4606651
YP_932478.1	CDS	groEL	NC_008702.1	1045775	1047424	D	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL	1045775..1047424	Azoarcus sp. BH72	4608940
YP_932479.1	CDS	basR	NC_008702.1	1047710	1048396	D	Probable two-component response regulatory protein,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC.; Specificity unclear; two-component response regulatory protein	1047710..1048396	Azoarcus sp. BH72	4608937
YP_932480.1	CDS	basS	NC_008702.1	1048371	1049858	D	Putative two-component system histidine kinase,; Specificity unclear; putative two-component system histidine kinase	1048371..1049858	Azoarcus sp. BH72	4608377
YP_932481.1	CDS	azo0977	NC_008702.1	1050037	1050345	D	Conserved hypothetical membrane protein. Homology to XCC4058 of Xanthomonas campestris of 55% (trembl|Q8P3L3) Has PF04341, Protein of unknown function,DUF485; IPR007436;This family includes several putative integral membrane proteins. no signal peptide 1 TMH; Conserved hypothetical protein; hypothetical protein	1050037..1050345	Azoarcus sp. BH72	4608378
YP_932482.1	CDS	actP	NC_008702.1	1050342	1052060	D	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease	1050342..1052060	Azoarcus sp. BH72	4606652
YP_932483.1	CDS	tctD	NC_008702.1	1052174	1052845	R	Probable transcriptional regulatory protein,Response_reg. IPR001867; Trans_reg_C. Pfam: PF00072; response_reg. PF00486; trans_reg_C. SMART: SM00448; REC. Transcriptional regulatory protein tctD. TRANSCRIPTIONAL ACTIVATOR OF THE TCTI TRICARBOXYLATE TRANSPORT SYSTEM OPERON.; Specificity unclear; transcriptional regulator	complement(1052174..1052845)	Azoarcus sp. BH72	4606653
YP_932484.1	CDS	hemA	NC_008702.1	1053183	1054436	D	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase	1053183..1054436	Azoarcus sp. BH72	4610012
YP_932485.1	CDS	prfA	NC_008702.1	1054469	1055554	D	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1	1054469..1055554	Azoarcus sp. BH72	4606654
YP_932486.1	CDS	hemK	NC_008702.1	1055551	1056387	D	Protein methyltransferase hemK (EC 2.1.1.-) (Protein-glutamine N- methyltransferase hemK) (Protein-(glutamine-N5) MTase hemK) (M.StyLTHemKP). Methylates the translation termination release factor RF1 on Gln-235 and RF2 on Gln-252.; Family membership; HemK protein	1055551..1056387	Azoarcus sp. BH72	4609623
YP_932487.1	CDS	azo0983	NC_008702.1	1056474	1056797	D	Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; hypothetical protein	1056474..1056797	Azoarcus sp. BH72	4608986
YP_932488.1	CDS	azo0984	NC_008702.1	1056828	1057925	R	Conserved hypothetical secreted protein. Homology to NE1634 of Nitrosomonas europaea of 34% (trembl|Q82U71(SRS)) No domains predicted. No TMHs Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(1056828..1057925)	Azoarcus sp. BH72	4606655
YP_932489.1	CDS	azo0985	NC_008702.1	1057916	1058776	R	Conserved hypothetical protein, 35% identity (56% similarity) to TrEMBL;Q82U70. Signal peptide Present. No TMH reported Present.; hypothetical protein	complement(1057916..1058776)	Azoarcus sp. BH72	4606656
YP_932490.1	CDS	azo0986	NC_008702.1	1058789	1059091	R	Hypothetical Protein. No Good functional or similar proteins matching in the database. No domains, repeats,motifs or features present.; hypothetical protein	complement(1058789..1059091)	Azoarcus sp. BH72	4606657
YP_932491.1	CDS	azo0987	NC_008702.1	1059121	1059837	R	Hypothetical protein predicted by Glimmer/Critica. No homology to data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(1059121..1059837)	Azoarcus sp. BH72	4606658
YP_932492.1	CDS	azo0988	NC_008702.1	1060017	1061303	R	Putative serine/threonine protein kinase,; Family membership; putative serine/threonine protein kinase	complement(1060017..1061303)	Azoarcus sp. BH72	4606659
YP_932493.1	CDS	argH	NC_008702.1	1061310	1062752	R	catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase	complement(1061310..1062752)	Azoarcus sp. BH72	4606660
YP_932494.1	CDS	algZ	NC_008702.1	1062841	1063866	D	Putative alginate biosynthesis protein AlgZ/FimS,; High confidence in function and specificity; putative alginate biosynthesis protein AlgZ/FimS	1062841..1063866	Azoarcus sp. BH72	4608337
YP_932495.1	CDS	algR	NC_008702.1	1063863	1064624	D	Probable alginate biosynthesis regulatory protein AlgR,; High confidence in function and specificity; alginate biosynthesis regulatory protein AlgR	1063863..1064624	Azoarcus sp. BH72	4608301
YP_932496.1	CDS	ppc	NC_008702.1	1064654	1067407	R	catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase	complement(1064654..1067407)	Azoarcus sp. BH72	4608298
YP_932497.1	CDS	hemC	NC_008702.1	1067713	1068663	D	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase	1067713..1068663	Azoarcus sp. BH72	4609608
YP_932498.1	CDS	hemD	NC_008702.1	1068679	1069476	D	Uroporphyrinogen-III synthase (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]). catalytic activity: hydroxymethylbilane = uroporphyrinogen-iii + h(2)o. pathway:porphyrin biosynthesis; fourth step. ribH: riboflavin synthase beta subunit; Specificity unclear; HemD protein	1068679..1069476	Azoarcus sp. BH72	4608981
YP_932499.1	CDS	hemX	NC_008702.1	1069486	1070682	D	Putative uroporphyrin-III C-methyltransferase. catalytic activity: 2 s-adenosyl-l-methionine + uroporphyrin iii = 2 s-adenosyl-l-homocysteine + sirohydrochlorin. pathway: siroheme and cobalamin biosynthesis.; Specificity unclear; uroporphyrin-III C-methyltransferase	1069486..1070682	Azoarcus sp. BH72	4608982
YP_932500.1	CDS	hemY	NC_008702.1	1070695	1071894	D	HemY protein. involved in a late step of protoheme ix synthesis.; High confidence in function and specificity; HemY protein	1070695..1071894	Azoarcus sp. BH72	4608989
YP_932501.1	CDS	glcC	NC_008702.1	1072050	1072769	D	Glc operon transcriptional activator,; High confidence in function and specificity; glc operon transcriptional activator	1072050..1072769	Azoarcus sp. BH72	4608990
YP_932502.1	CDS	glcD1	NC_008702.1	1072863	1074362	D	Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity; glycolate oxidase subunit GlcD	1072863..1074362	Azoarcus sp. BH72	4608879
YP_932503.1	CDS	azo0999	NC_008702.1	1074367	1074513	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal pepitde. 1 TMH; hypothetical protein	1074367..1074513	Azoarcus sp. BH72	4608880
YP_932504.1	CDS	glcE	NC_008702.1	1074510	1075571	D	Probable glycolate oxidase subunit GlcE. Homology to glcE of E. coli of 47% (sprot|GLCE_ECOLI) InterPro: FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain Tigrfam: glcD: glycolate oxidase subunit GlcD no singla peptide no TMHs; High confidence in function and specificity; glycolate oxidase FAD binding subunit	1074510..1075571	Azoarcus sp. BH72	4606661
YP_932505.1	CDS	glcF	NC_008702.1	1075575	1076819	D	Probable glycolate oxidase iron-sulfur subunit. Homology to glcF of E. coli of 56% (sprot|GLCF_ECOLI) Pfam: Domain of unknown function (DUF224) (192-256 aa; 329-391 aa) no signal peptide no TMHs; High confidence in function and specificity; glycolate oxidase iron-sulfur subunit	1075575..1076819	Azoarcus sp. BH72	4608882
YP_932506.1	CDS	azo1002	NC_008702.1	1076945	1077721	D	Putative phosphoprotein phosphatase,; Conserved hypothetical protein; putative phosphoprotein phosphatase	1076945..1077721	Azoarcus sp. BH72	4608883
YP_932507.1	CDS	pntAA	NC_008702.1	1077900	1079021	D	Probable NAD(P) transhydrogenase, subunit alpha part 1. Homology to pntAA of R. rubrum of 44% (sprot|PNAA_RHORU). The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. Tirfam: pntA: NAD(P) transhydrogenase alpha subunit Pfam: Alanine dehydrogenase/pyridine nucleotide dehydrogenase no signal peptide no TMHs; High confidence in function and specificity; NAD(P) transhydrogenase subunit alpha part 1	1077900..1079021	Azoarcus sp. BH72	4606662
YP_932508.1	CDS	pntAB	NC_008702.1	1079035	1079343	D	Conserved hypothetical NAD(P) transhydrogenase,subunit alpha part 2. Homology to pntA of X. axonopodis of 74% (trembl|Q8PNW6). The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. 3 TMHs no signal peptide; High confidence in function and specificity; NAD(P) transhydrogenase subunit alpha part 2	1079035..1079343	Azoarcus sp. BH72	4609590
YP_932509.1	CDS	pntB	NC_008702.1	1079340	1080719	D	Probable NAD(P) transhydrogenase, subunit beta. Homology to pntB of R. rubrum of 46% (sprot|PNTB_RHORU) The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. Pfam: NAD(P) transhydrogenase beta subunit signal peptide 7 TMHs; High confidence in function and specificity; NAD(P) transhydrogenase subunit beta	1079340..1080719	Azoarcus sp. BH72	4609591
YP_932510.1	CDS	azo1006	NC_008702.1	1080834	1081184	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	1080834..1081184	Azoarcus sp. BH72	4609592
YP_932511.1	CDS	azo1007	NC_008702.1	1081178	1083613	R	Hypothetical signaling protein; signaling protein	complement(1081178..1083613)	Azoarcus sp. BH72	4606663
YP_932512.1	CDS	rhlE2	NC_008702.1	1083711	1085195	R	Putative ATP-dependent RNA helicase rhlE.; Family membership; putative ATP-dependent RNA helicase	complement(1083711..1085195)	Azoarcus sp. BH72	4606664
YP_932513.2	CDS	azo1009	NC_008702.1	1085393	1086454	R	Conserved hypothetical protein. Homology to xcc0816 of X. campestris of 49% (trembl|Q8PCB8) Pfam: FtsJ-like methyltransferase no signal peptide no TMHs; putative RNA 2'-O-ribose methyltransferase	complement(1085393..1086454)	Azoarcus sp. BH72	4609717
YP_932514.1	CDS	tas	NC_008702.1	1086606	1087658	D	Probable oxidoreductase Tas. Homology to tas of E. coli of 51% (sprot|TAS_ECOLI). InterPro: Aldo/keto reductase family (IPR001395) Pfam: Aldo/keto reductase family no signal peptide no TMHs; Function unclear; oxidoreductase Tas	1086606..1087658	Azoarcus sp. BH72	4606665
YP_932515.1	CDS	azo1011	NC_008702.1	1087666	1088040	R	Conserved hypothetical secreted protein. Homology to Rgel02001790 of Rubrivivax gelatinosus of 45% (gi|47573892|ref|ZP_00243929.1|(NBCI ENTREZ)) . No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(1087666..1088040)	Azoarcus sp. BH72	4609917
YP_932516.1	CDS	ugpB	NC_008702.1	1088233	1089531	D	Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present.; High confidence in function and specificity; putative glycerol-3-phosphate-binding periplasmic protein	1088233..1089531	Azoarcus sp. BH72	4606666
YP_932517.1	CDS	ugpQ	NC_008702.1	1089536	1090285	D	hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase	1089536..1090285	Azoarcus sp. BH72	4610065
YP_932518.1	CDS	ispB	NC_008702.1	1090402	1091427	D	Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of polyprenyl synthetase enzymes which catalyze a 1'4-condensation between 5 carbon isoprene units. It has been shown that all the above enzymes share some regions of sequence similarity. Two of these regions are rich in aspartic-acid residues and could be involved in the catalytic mechanism and/or the binding of the substrates.; High confidence in function and specificity; octaprenyl-diphosphate synthase	1090402..1091427	Azoarcus sp. BH72	4610066
YP_932519.1	CDS	azo1015	NC_008702.1	1091631	1092566	D	Probable transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	1091631..1092566	Azoarcus sp. BH72	4610013
YP_932520.1	CDS	lldA	NC_008702.1	1092645	1093793	D	L-lactate dehydrogenase. Homology to lldA of N. meningitidis of 72% (trembl|Q51135). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Proteins binding FMN and related compounds core region (IPR003009 Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs; High confidence in function and specificity; L-lactate dehydrogenase	1092645..1093793	Azoarcus sp. BH72	4606667
YP_932521.1	CDS	comL	NC_008702.1	1093840	1094649	R	probable competence lipoprotein comL precursor. Homology to comL of N. gonorrhoeae of 47% (sprot|COML_NEIGO(SRS)) REQUIRED FOR EFFICIENT TRANSFORMATION OF NEISSERIA MENINGITIDIS BY SPECIES-RELATED DNA (By similarity). InterPro: TPR repeat (IPR001440) no signal peptide no TMH ccoS: cytochrome oxidase maturation pro; High confidence in function and specificity; competence lipoprotein	complement(1093840..1094649)	Azoarcus sp. BH72	4609164
YP_932522.1	CDS	rluD	NC_008702.1	1094663	1095637	D	Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil at positions 1911 1915 and 1917 in 23S ribosomal RNA.; Family membership; pseudouridylate synthase	1094663..1095637	Azoarcus sp. BH72	4608512
YP_932523.1	CDS	azo1019	NC_008702.1	1095700	1096395	D	Conserved hypothetical protein. Homology to CV2191 of C.violaceum of 64% (tremble:Q7NVZ9). Has PF02578,Uncharacterised ACR, YfiH family COG1496. InterPro;IPR003730. No signal peptide. No TMHs. TIGR00726: conserved hypothetical protein; hypothetical protein	1095700..1096395	Azoarcus sp. BH72	4609734
YP_932524.1	CDS	azo1020	NC_008702.1	1096434	1096655	R	Conserved hypothetical membrane protein. Homology to RS03993 of R.solanacearum of 48% (trembl|Q8XYX6(SRS)). No domains. No signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(1096434..1096655)	Azoarcus sp. BH72	4606668
YP_932525.1	CDS	phaC	NC_008702.1	1096743	1098485	D	Entry name :- TREMBL:Q9ZB54 Prim. accession # Q9ZB54 Identities = 290/560 (51%) InterPro:- IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam:- PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Prediction: Signal peptide Signal peptide probability: 0.999 Number of predicted TMHs: 0; Family membership; polyhydroxyalkanoate synthase	1096743..1098485	Azoarcus sp. BH72	4606669
YP_932526.1	CDS	phbB1	NC_008702.1	1098596	1099336	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (60% identity); TREMBL:Q8XYX3 (59% identity). Pfam (PF00106): Short chain dehydrogenase.; High confidence in function and specificity; acetoacetyl-CoA reductase	1098596..1099336	Azoarcus sp. BH72	4609535
YP_932527.1	CDS	phbB2	NC_008702.1	1099528	1100268	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (62% identity); TREMBL:Q8XYX3 (62% identiy). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. SignalP reporting signal peptide.; High confidence in function and specificity; acetoacetyl-CoA reductase	1099528..1100268	Azoarcus sp. BH72	4609539
YP_932528.1	CDS	phbF	NC_008702.1	1100389	1101018	D	phbF protein, 57% identity to TrEMBL;Q7NYA7. Has 2 copies of PF05233, PHB accumulation regulatory domain;IPR007897, PHB_accumulat: The proteins this domain is found in are typically involved in regulating polymer accumulation in bacteria, particularly poly-beta-hydroxybutyrate (PHB); High confidence in function and specificity; hypothetical protein	1100389..1101018	Azoarcus sp. BH72	4609540
YP_932529.1	CDS	rimO	NC_008702.1	1101080	1102411	D	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase	1101080..1102411	Azoarcus sp. BH72	4609543
YP_932530.1	CDS	ychK	NC_008702.1	1102525	1103373	D	Hypothetical protein ychK. TREMBL:Q89IT4: 42% identity, 58% similarity InterPro: Uncharacterized protein family UPF0028 InterPro:IPR002641; Patatin. Pfam:PF01734; Patatin hypA: hydrogenase expression/formation Non-secretory protein with signalpeptide probability:0.141 (SignalP predicted) Absence of TMH's; Family membership; esterase	1102525..1103373	Azoarcus sp. BH72	4606670
YP_932531.1	CDS	glcD2	NC_008702.1	1103397	1104803	D	Putative glycolate oxidase subunit GlcD. Homology to glcD of E. coli of 32% (sprot|GLCD_ECOLI). InterPro: FAD linked oxidase C-terminal (IPR004113);m FAD linked oxidas, N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership; putative glycolate oxidase subunit GlcD	1103397..1104803	Azoarcus sp. BH72	4610160
YP_932532.1	CDS	hbdA	NC_008702.1	1105799	1106650	D	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase	1105799..1106650	Azoarcus sp. BH72	4609988
YP_932533.1	CDS	rho	NC_008702.1	1106727	1108178	R	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho	complement(1106727..1108178)	Azoarcus sp. BH72	4608978
YP_932534.1	CDS	trxA1	NC_008702.1	1108162	1108488	R	Thioredoxin-disulfide reductase. Homology to trxA of T. ferrooxidans of 69% (THIO_THIFE). Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide. InterPro: Thioredoxin (IPR006662) Pfam: Thioredoxin no signal peptide no TMHs; Specificity unclear; thioredoxin-disulfide reductase	complement(1108162..1108488)	Azoarcus sp. BH72	4609719
YP_932535.1	CDS	fdxA	NC_008702.1	1108784	1109107	D	Probable ferredoxin. Homology to fdxA of A. vineladii of 66% (sprot|FER1_AZOVI(SRS)). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN COULD PLAY A ROLE IN REGULATING GENE EXPRESSION BY INTERACTING DIRECTLY WITH DNA. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain IPR001450); 7Fe ferredoxin (IPR000813) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity; ferredoxin	1108784..1109107	Azoarcus sp. BH72	4610039
YP_932536.1	CDS	azo1032	NC_008702.1	1109179	1109628	D	TREMBL:Q8XZ43; 52% identity, 70% similarity. TREMBL:Q8F5Y8; 30% identity, 56% similarity. Protein At5g10860 mitochondrial precursor. IPR000644: CBS domain Pfam:PF00571 - GARS_N TIGRFAM: rrf2 family, KpsF/GutQ family (by similarity) kpsF: KpsF/GutQ family protein; Specificity unclear; hypothetical protein	1109179..1109628	Azoarcus sp. BH72	4608747
YP_932537.1	CDS	fadD1	NC_008702.1	1109767	1111458	D	Esterification concomitant with transport of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q7NY16 (61% identity); TREMBL:Q7WLG0 (63% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme.; High confidence in function and specificity; long-chain-fatty-acid-CoA ligase	1109767..1111458	Azoarcus sp. BH72	4606671
YP_932538.1	CDS	ilvB	NC_008702.1	1111730	1113397	D	Acetolactate synthase isozyme I large subunit (AHAS-I) (Acetohydroxy-acid synthase I large subunit) (ALS-I). InterPro: Acetolactate synthase large subunit biosynthetic type acolac_lg: acetolactate synthase large subunit,biosynthetic type; High confidence in function and specificity; acetolactate synthase catalytic subunit	1111730..1113397	Azoarcus sp. BH72	4608722
YP_932539.1	CDS	ilvN	NC_008702.1	1113400	1113714	D	with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit	1113400..1113714	Azoarcus sp. BH72	4609069
YP_932540.1	CDS	aroC	NC_008702.1	1113825	1114961	D	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase	1113825..1114961	Azoarcus sp. BH72	4609076
YP_932541.1	CDS	azo1037	NC_008702.1	1114958	1116148	D	Putative transport protein. Similarity to sugar transporters (lacY): lactose permease 2A0105.Similar to POT family of proteins with DUF domains and 12 transmembrane helices. 31% identity and 47% similarity to putative MFS metabolite transporter from Pseudomonas aeruginosa PA01; Family membership; putative MFS metabolite transporter	1114958..1116148	Azoarcus sp. BH72	4608344
YP_932542.1	CDS	azo1038	NC_008702.1	1116163	1116984	D	Conserved hypothetical secreted protein. Homology to bb2112 of B. bronchiseptica of 55% (trembl|Q7WKJ4). Pfam: Peptidase family M48 signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	1116163..1116984	Azoarcus sp. BH72	4606672
YP_932543.1	CDS	leuC	NC_008702.1	1117079	1118488	D	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit	1117079..1118488	Azoarcus sp. BH72	4606673
YP_932544.1	CDS	leuD	NC_008702.1	1118505	1119143	D	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit	1118505..1119143	Azoarcus sp. BH72	4609132
YP_932545.1	CDS	leuB	NC_008702.1	1119180	1120244	D	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase	1119180..1120244	Azoarcus sp. BH72	4609133
YP_932546.1	CDS	asd	NC_008702.1	1120327	1121427	D	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase	1120327..1121427	Azoarcus sp. BH72	4609131
YP_932547.1	CDS	fimV1	NC_008702.1	1121643	1124558	D	In Pseudomonas aeruginosa, FimV ist probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (28%). Pfam (PF01476): LysM domain Pfam (PF04102): SlyX, may be a coiled-coil structure SignalP reporting Signal peptide; Function unclear; putative type 4 pilus biogenesis	1121643..1124558	Azoarcus sp. BH72	4608357
YP_932548.1	CDS	azo1044	NC_008702.1	1124621	1125232	D	Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership; hypothetical protein	1124621..1125232	Azoarcus sp. BH72	4608764
YP_932549.1	CDS	truA	NC_008702.1	1125226	1126023	D	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A	1125226..1126023	Azoarcus sp. BH72	4606674
YP_932550.1	CDS	trpF	NC_008702.1	1126024	1126647	D	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase	1126024..1126647	Azoarcus sp. BH72	4606675
YP_932551.1	CDS	trpB	NC_008702.1	1126595	1127848	D	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta	1126595..1127848	Azoarcus sp. BH72	4610034
YP_932552.1	CDS	trpA	NC_008702.1	1127891	1128706	D	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha	1127891..1128706	Azoarcus sp. BH72	4610030
YP_932553.1	CDS	accD	NC_008702.1	1128703	1129575	D	Function:-THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A CARBOXYLASE COMPLEX; FIRST BIOTIN CARBOXYLASE CATALYZES THE CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA (BY SIMILARITY). Entry name :-SWISSPROT:ACCD_ECOLI Prim. accession # P08193 Identities = 178/287 (62%) InterPro:- IPR000438; ACoACC_transB. IPR000022; Carboxyl_trans. Pfam:- PF01039; Carboxyl_trans; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; High confidence in function and specificity; acetyl-coenzyme A carboxylase carboxyl transferase subunit b	1128703..1129575	Azoarcus sp. BH72	4610029
YP_932554.1	CDS	folC	NC_008702.1	1129592	1130890	D	FolC bifunctional protein [Includes: Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); Dihydrofolate synthase (EC 6.3.2.12)]. Conversion of folates to polyglutamate derivatives.; High confidence in function and specificity; dihydrofolate synthase/tetrahydrofolylpolyglutamate synthase	1129592..1130890	Azoarcus sp. BH72	4608258
YP_932555.1	CDS	azo1051	NC_008702.1	1130902	1131543	D	Conserved hypothetical membrane proteine. Homology to BB2598 of Bordetella bronchiseptica of 37% (trembl|Q7WJA1(SRS)). Has 2 copies of PF05036, Sporulation related repeat;IPR007730, SPOR; This 35 residue repeat is found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This repeat might be involved in binding peptidoglycan (Bateman A pers obs). FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localises to the septum ring complex. The CwlM gene is a cell wall hydrolase so this repeat may help localise the protein to the cell wall. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	1130902..1131543	Azoarcus sp. BH72	4608819
YP_932556.1	CDS	cvpA	NC_008702.1	1131554	1132045	D	Colicin V production protein (dedE protein) (Pur regulon 18 kDa protein). REQUIRED FOR COLICIN V PRODUCTION FROM PLASMID INCFI COLV3-K30. TREMBL:Q82WH7: 29% identity,38% similarity InterPro:IPR003825; Colicin_V. Pfam:PF02674; Colicin_V TIGR00304: conserved hypothetical protei Signal peptide present (Signal P predicted) TMH's 4 (TMHMM predicted); High confidence in function and specificity; putative colicin V production protein	1131554..1132045	Azoarcus sp. BH72	4606676
YP_932557.1	CDS	purF	NC_008702.1	1132057	1133586	D	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase	1132057..1133586	Azoarcus sp. BH72	4608546
YP_932558.1	CDS	metZ	NC_008702.1	1133594	1134763	D	catalyzes the conversion of O-succinylhomoserine into homocysteine; O-succinylhomoserine sulfhydrylase	1133594..1134763	Azoarcus sp. BH72	4609659
YP_932559.1	CDS	lpxH	NC_008702.1	1134854	1135654	R	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase	complement(1134854..1135654)	Azoarcus sp. BH72	4609213
YP_932560.1	CDS	ppiB	NC_008702.1	1135647	1136141	R	Peptidyl-prolyl cis-trans isomerase B. Homology to ppiB of E.coli of 71% (sprot|PPIB_ECOLI). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase(IPR002130) Pfam: Cyclophilin-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMH; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase B	complement(1135647..1136141)	Azoarcus sp. BH72	4609178
YP_932561.1	CDS	ppiA	NC_008702.1	1136158	1136739	R	Probable peptidyl-prolyl cis-trans isomerase. Homology to ppiA of E. coli of 56% (SWISSPROT:PPIA_ECOLI) PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase (IPR002130) Pfam: Cyclophilin-type peptidyl-prolyl cis-trans isomerase Signal peptide no TMHs; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase A	complement(1136158..1136739)	Azoarcus sp. BH72	4609610
YP_932562.1	CDS	azo1058	NC_008702.1	1136784	1137980	R	Conserved hypothetical secreted proteins. Homology to of Dechloromonas aromatica of 56% (gi|41723709|ref|ZP_00150619.1|(NBCI ENTREZ)). Signal Peptide Present. No TMH present. Has PF03734:(IPR005490)ErfK/YbiS/YcfS/YnhG;This family of proteins are found in a range of bacteria. The conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate.; Conserved hypothetical protein; hypothetical protein	complement(1136784..1137980)	Azoarcus sp. BH72	4609609
YP_932563.1	CDS	azo1059	NC_008702.1	1137983	1139239	R	Conserved hypothetical secreted protein. Homology to Daro03002816 of Dechloromonas aromatica of 42% (gi|53730051|ref|ZP_00348646.1|(NBCI ENTREZ)). domain structure: 59 aa - 92 aa TRP; 93 aa- 126 aa TRP; 127 aa -155 aa TRP. InterPro: TPR repeat (IPR001440); Type I antifreeze protein (IPR000104). Pfam: TRP Domain. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(1137983..1139239)	Azoarcus sp. BH72	4606677
YP_932564.1	CDS	cysS	NC_008702.1	1139410	1140792	D	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase	1139410..1140792	Azoarcus sp. BH72	4606678
YP_932565.1	CDS	azo1061	NC_008702.1	1140857	1142011	R	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to trembl|Q8XQ39 (40%) and to trembl|Q89G00 (32%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Family membership; extracellular ligand binding protein	complement(1140857..1142011)	Azoarcus sp. BH72	4608564
YP_932566.1	CDS	dnaJ1	NC_008702.1	1142201	1143328	R	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ	complement(1142201..1143328)	Azoarcus sp. BH72	4606679
YP_932567.1	CDS	dnaK	NC_008702.1	1143424	1145349	R	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK	complement(1143424..1145349)	Azoarcus sp. BH72	4608634
YP_932568.1	CDS	grpE	NC_008702.1	1145464	1146030	R	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE	complement(1145464..1146030)	Azoarcus sp. BH72	4608636
YP_932569.1	CDS	azo1065	NC_008702.1	1146167	1146412	D	Conserved hypothetical protein. Homology to an orf of Polaromonas sp. JS666 of 43% ( ZP_00361754). No domains predicted. No singal peptide. No TMHs; hypothetical protein	1146167..1146412	Azoarcus sp. BH72	4608942
YP_932570.1	CDS	gyrA	NC_008702.1	1146520	1149153	D	negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A	1146520..1149153	Azoarcus sp. BH72	4606680
YP_932571.1	CDS	serC	NC_008702.1	1149150	1150247	D	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase	1149150..1150247	Azoarcus sp. BH72	4608975
YP_932572.1	CDS	pheA	NC_008702.1	1150262	1151326	D	Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity; chorismate mutase/prephenate dehydratase	1150262..1151326	Azoarcus sp. BH72	4609867
YP_932573.1	CDS	hisC1	NC_008702.1	1151344	1152441	D	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase	1151344..1152441	Azoarcus sp. BH72	4609544
YP_932574.1	CDS	tyrA	NC_008702.1	1152457	1153347	D	Prephenate dehydrogenases are involved in tyrosine biosynthesis. Similar to trembl|Q7NSL5 (54%) and to trembl|Q82XD9 (47%). Pfam: PDH, Prephenate dehydrogenase. TMHMM reporting one Tmhelix. SignalP reporting Signal peptide.; Specificity unclear; prephenate dehydrogenase	1152457..1153347	Azoarcus sp. BH72	4609001
YP_932575.1	CDS	aroA	NC_008702.1	1153344	1155305	D	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; catalyzes CMP phosphorylation; bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidine monophosphate kinase	1153344..1155305	Azoarcus sp. BH72	4610054
YP_932576.1	CDS	rpsA	NC_008702.1	1155409	1157115	D	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1	1155409..1157115	Azoarcus sp. BH72	4608342
YP_932577.1	CDS	ihfB	NC_008702.1	1157126	1157410	D	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta	1157126..1157410	Azoarcus sp. BH72	4609805
YP_932578.1	CDS	azo1074	NC_008702.1	1157501	1157806	D	38% identity with Hypothetical protein from Chromobacterium violaceum TrEMBL:Q7NTL0,Genename CV3044 Signal Peptide present TMHMM reporting for transmembrane helices:2 present.; Conserved hypothetical protein; hypothetical protein	1157501..1157806	Azoarcus sp. BH72	4609067
YP_932579.1	CDS	azo1075	NC_008702.1	1157814	1158989	D	Putative N-acetylglucosaminyl transferase. Enzyme that is involved in the catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol. 36% Cas_TM1810_C.IPR001574; RIP.IPR001440; TPR.IPR008941; TPR-like.InterPro: TPR repeat TIGRFAMs:TIGR01870; cas_TM1810; 1. TMHx:1; Specificity unclear; tetratricopeptide repeat protein	1157814..1158989	Azoarcus sp. BH72	4606681
YP_932580.1	CDS	ugd	NC_008702.1	1159107	1160429	D	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).; High confidence in function and specificity; UDP-glucose 6-dehydrogenase	1159107..1160429	Azoarcus sp. BH72	4606682
YP_932581.1	CDS	cysM	NC_008702.1	1160583	1161473	D	catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B	1160583..1161473	Azoarcus sp. BH72	4610064
YP_932582.1	CDS	azo1078	NC_008702.1	1161512	1162306	D	Probable DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A). TIGR00099: conserved hypothetical protein.; Function unclear; hypothetical protein	1161512..1162306	Azoarcus sp. BH72	4608561
YP_932583.1	CDS	thrS	NC_008702.1	1162660	1164576	D	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase	1162660..1164576	Azoarcus sp. BH72	4610025
YP_932584.1	CDS	infC	NC_008702.1	1164657	1165127	D	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3	1164657..1165127	Azoarcus sp. BH72	4606684
YP_932585.1	CDS	rpmI	NC_008702.1	1165275	1165472	D	50S ribosomal protein L35.; Family membership; 50S ribosomal protein L35	1165275..1165472	Azoarcus sp. BH72	4609084
YP_932586.1	CDS	rplT	NC_008702.1	1165485	1165844	D	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20	1165485..1165844	Azoarcus sp. BH72	4609792
YP_932587.1	CDS	pheS	NC_008702.1	1165911	1166942	D	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha	1165911..1166942	Azoarcus sp. BH72	4609779
YP_932588.1	CDS	pheT	NC_008702.1	1166949	1169339	D	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta	1166949..1169339	Azoarcus sp. BH72	4609546
YP_932589.1	CDS	ihfA	NC_008702.1	1169336	1169647	D	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha	1169336..1169647	Azoarcus sp. BH72	4609547
YP_932590.1	CDS	azo1086	NC_008702.1	1169628	1170008	D	Putative MerR-family transcriptional regulator,similar toTREMBL: trembl|Q83C17 (51% Coxiella burnetii,cbu1319) Pfam: PF00376 MerR family regulatory protein. HTH reporting nucleic acid binding motif.; MerR family transcriptional regulator	1169628..1170008	Azoarcus sp. BH72	4609066
YP_932591.1	CDS	surE	NC_008702.1	1170324	1171067	D	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE	1170324..1171067	Azoarcus sp. BH72	4610014
YP_932592.1	CDS	pcm2	NC_008702.1	1171112	1171717	D	Protein-L-isoaspartate O-methyltransferase, 56% Identity to TrEMBL;Q7VXN1.51% Identity to TrEMBL;Q82VW0,Q7NRV0. SProt;Q886L4(52% Idnetity), Q87LQ6(51%),P24206(47%) Has PF01135, Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);IPR000682, PCMT; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MEDLINE: (which is also known as L-isoaspartyl protein carboxyl methyltransferase) is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to the free carboxyl groups of D-aspartyl or L-isoaspartyl residues in a variety of peptides and proteins. The enzyme does not act on normal L-aspartyl residues L-isoaspartyl and D-aspartyl are the products of the spontaneous deamidation and/or isomerization of normal L-aspartyl and L- asparaginyl residues in proteins. PCMT plays a role in the repair and/or degradation of these damaged proteins; the enzymatic methyl esterification of the abnormal residues can lead to their conversion to normal L-aspartyl residues.; protein-L-isoaspartate (D-aspartate) O-methyltransferase	1171112..1171717	Azoarcus sp. BH72	4609911
YP_932593.1	CDS	nlpD	NC_008702.1	1171714	1172622	D	Conserved hypothetical lipoprotein. Homology to nlpD of R. gelatinosus of 43% (trembl|Q9JP90) InterPro: Peptidase family M23/M37 (IPR002886); LysM motif (IPR002482) Pfam: LysM domain; Peptidase family m23/M27 signal peptide no TMHs; Conserved hypothetical protein; lipoprotein	1171714..1172622	Azoarcus sp. BH72	4609511
YP_932594.1	CDS	rpoS	NC_008702.1	1172633	1173568	D	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS	1172633..1173568	Azoarcus sp. BH72	4609384
YP_932595.1	CDS	mltB	NC_008702.1	1173565	1174575	R	Putative membrane-bound lytic murein transglycosylase. homology to mltb of E. coli of 38% (sprot|MLTB_ECOLI) Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. no domains prediced signal peptide no TMHs; Family membership; putative membrane-bound lytic murein transglycosylase	complement(1173565..1174575)	Azoarcus sp. BH72	4609802
YP_932596.1	CDS	azo1092	NC_008702.1	1174572	1176551	R	Conserved hypotetical membrane protein. Homology to RSp0111 of R. solanacearum of 41% (trembl|Q8XTJ7(SRS)) Pfam: Transglutaminase-like superfamily signal peptide probable 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1174572..1176551)	Azoarcus sp. BH72	4609228
YP_932597.1	CDS	azo1093	NC_008702.1	1176544	1177527	R	Conserved hypothetical membrane protein. Homology to RS03012 of Ralstonia solanacearum of 40% (trembl|Q8XTJ8) InterPro: Protein of unknown function DUF58 This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterterPro: IPR002881; DUF58. Pfam: PF01882; DUF58; Non-secretory with low signal peptide probability (Signal P predicted). TMHMM predicted 2 transmembrane helices.; Conserved hypothetical protein; hypothetical protein	complement(1176544..1177527)	Azoarcus sp. BH72	4606686
YP_932598.1	CDS	moxR1	NC_008702.1	1177527	1178444	R	MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBL:Q883V0: 60% identity, 73% similarity SMART: SM00382; AAA InterPro: IPR003593; AAA_ATPase. IPR001270; Chaprnin_clpA/B. IPR003442; UPF0079. Pfam: PF02367; UPF0079; Pfam: Mg_chelatase:Magnesium chelatase, subunit ChlI ruvB: Holliday junction DNA helicase Ru No signal peptide and transmembrane helices; High confidence in function and specificity; MoxR protein	complement(1177527..1178444)	Azoarcus sp. BH72	4606687
YP_932599.1	CDS	azo1095	NC_008702.1	1178599	1179525	D	Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are all members of an ancient protein superfamily, TREMBL:Q7VZF1 (58% identity); TREMBL:Q7NRU4 (57% identity). InterPro (IPR000286): Histone deacetylase family Pfam (PF00850): Histone deacetylase domain.; Family membership; histone deacetylase family protein	1178599..1179525	Azoarcus sp. BH72	4609264
YP_932600.1	CDS	dapA	NC_008702.1	1179632	1180510	D	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase	1179632..1180510	Azoarcus sp. BH72	4606688
YP_932601.1	CDS	nlpB	NC_008702.1	1180537	1181676	D	Putative lipoprotein. Homology to nlpB of E. coli of 20% (sprot|NLPB_ECOLI) This family consists of a number of bacterial lipoproteins often known as NlpB or DapX. This lipoprotein is detected in outer membrane vesicles in Escherichia coli and appears to be nonessential. Pfam: NlpB/DapX lipoprotein singal peptide no TMHs; Family membership; putative lipoprotein	1180537..1181676	Azoarcus sp. BH72	4608580
YP_932602.1	CDS	azo1098	NC_008702.1	1181789	1182073	R	Conserved hypothetical secreted protein. Homology to NMB1523 of N.meningitidis of 50% (tremble:Q9JYL7) No domains predicted. No TMHs Signal Peptide present.; Conserved hypothetical protein; hypothetical protein	complement(1181789..1182073)	Azoarcus sp. BH72	4609383
YP_932603.1	CDS	azo1099	NC_008702.1	1182332	1183447	R	Conserved hypothetical protein. Homology to CV3581 of C.violaceum of 48% (tremble:Q7NS46) SM00558;JmjC:Probable enzymes, but of unknown functions,that regulate chromatin reorganisation processes. No signal peptide or TMH present. lytR_cpsA_psr: cell envelope-related fu; hypothetical protein	complement(1182332..1183447)	Azoarcus sp. BH72	4606689
YP_932604.1	CDS	rumA	NC_008702.1	1183539	1184840	D	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase	1183539..1184840	Azoarcus sp. BH72	4606690
YP_932605.1	CDS	azo1101	NC_008702.1	1185090	1185695	D	Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Family membership; pseudouridylate synthase	1185090..1185695	Azoarcus sp. BH72	4610016
YP_932606.1	CDS	azo1102	NC_008702.1	1185730	1186185	D	Conserved hypothetical secreted protein. Homology to rsc2494 of R. solanacearum of 48% (trembl|Q8XWI0(SRS)). Pfam: DUF192 signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	1185730..1186185	Azoarcus sp. BH72	4606692
YP_932607.1	CDS	flhB	NC_008702.1	1186321	1187466	D	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB	1186321..1187466	Azoarcus sp. BH72	4606693
YP_932608.1	CDS	flhA	NC_008702.1	1187481	1189580	D	membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA	1187481..1189580	Azoarcus sp. BH72	4608790
YP_932609.1	CDS	flhF	NC_008702.1	1189724	1191256	D	positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF	1189724..1191256	Azoarcus sp. BH72	4608789
YP_932610.1	CDS	fleN	NC_008702.1	1191259	1192041	D	Hypothetical flagellar related protein FleN. Homology to fleN of Pseudomonas fluorescens of 27% (AAN03366). No domains predicted. No signal peptide. No TMHs; flagellar-like protein FleN	1191259..1192041	Azoarcus sp. BH72	4608793
YP_932611.1	CDS	fliA	NC_008702.1	1192166	1192936	D	RNA polymerase sigma factor for flagellar operon (Sigma-F factor) (Sigma-27) (Sigma-28). THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS ALTERNATIVE SIGMA FACTOR IS SPECIFIC FOR CLASS 3 FLAGELLAR OPERONS. Similar to SWISSPROT: sprot|FLIA_PSEAE (46% Pseudomonas aeruginosa, RNA polymerase sigma factor for flagellar operon (sigma-f factor) (sigma-28)). InterPro: IPR000943 Sigma_70. Pfam: PF00140 Sigma-70 factor, region 1.2. HTH reporting nucleic acid binding motif. gatB_rel: aspartyl-tRNA(Asn) amidotrans; High confidence in function and specificity; RNA polymerase sigma factor	1192166..1192936	Azoarcus sp. BH72	4608773
YP_932612.1	CDS	motC	NC_008702.1	1193004	1193744	D	homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC; flagellar motor protein	1193004..1193744	Azoarcus sp. BH72	4608794
YP_932613.1	CDS	tar	NC_008702.1	1193801	1195465	R	E. coli uses five MCP-family receptors to promote chemotactic movements toward different attractant compounds: Tar is the aspartate and maltose chemoreceptor. Methyl-accepting chemotaxis protein,; Specificity unclear; putative aspartate chemoreceptor protein	complement(1193801..1195465)	Azoarcus sp. BH72	4606694
YP_932614.1	CDS	motB1	NC_008702.1	1195645	1196484	D	Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; flagellar motor protein MotD	1195645..1196484	Azoarcus sp. BH72	4609916
YP_932615.1	CDS	dcrH2	NC_008702.1	1196592	1197074	D	DcrH:hemerythrin protein, is transmembrane methyl-accepting protein probably involved in bacterial chemotaxis . 31% Hemerythrin. Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity; putative hemerythrin-like protein	1196592..1197074	Azoarcus sp. BH72	4609262
YP_932616.1	CDS	azo1112	NC_008702.1	1197195	1199600	R	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A	complement(1197195..1199600)	Azoarcus sp. BH72	4608591
YP_932617.1	CDS	azo1113	NC_008702.1	1199800	1200315	R	Conserved hypothetical protein. Homology to Bucepa03000705 of Burkholderia cepacia of 33% (gi|46323973|ref|ZP_00224335.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1199800..1200315)	Azoarcus sp. BH72	4606695
YP_932618.1	CDS	lhpp	NC_008702.1	1200393	1201181	R	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. Enzyme that hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine,phosphohistidine and imidodiphosphate in vitro. 38% HAD_SF_IIA.IPR006355; HAD_SF_IIA_hyp2.IPR005834; Hydrolase. Pfam:PF00702;Hydrolase; 1. TIGRFAMs:TIGR01460; HAD-SF-IIA; 1.TIGR01458; HAD-SF-IIA-hyp3; 1. TMHelix:1; High confidence in function and specificity; putative inorganic pyrophosphate phosphatase	complement(1200393..1201181)	Azoarcus sp. BH72	4606696
YP_932619.1	CDS	parE	NC_008702.1	1201275	1203248	R	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B	complement(1201275..1203248)	Azoarcus sp. BH72	4609137
YP_932620.1	CDS	azo1116	NC_008702.1	1203341	1203955	R	Conserved hypothetical membrane protein,TrEMBL;Q8NSJ9(49% identity,73% similarity),TrEMBL;Q7VSN7(53% identity, 72% similarity). Has 2 PF03458(IPR005115 ):UPF0126 domain;Domain always found as pair in bacterial membrane proteins of unknown function. This domain contains three transmembrane helices. The conserved glycines are suggestive of an ion channel (C. Yeats unpublished obs.). signal peptide 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1203341..1203955)	Azoarcus sp. BH72	4609501
YP_932621.1	CDS	aceA	NC_008702.1	1204519	1205832	R	Isocitrate lyase. Homology to aceA of E. coli of 73% (sprot|ACEA_ECOLI). Isocitrate lyase is an enzyme that catalyzes the conversion of isocitrate to succinate and glyoxylate. This is the first step in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants. InterPro: Isocitrate lyase (IPR000918) Pfam: Isocitrate lyase family no signal peptide no TMHs; High confidence in function and specificity; AceA protein	complement(1204519..1205832)	Azoarcus sp. BH72	4606697
YP_932622.1	CDS	azo1118	NC_008702.1	1206325	1207365	D	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	1206325..1207365	Azoarcus sp. BH72	4608259
YP_932623.1	CDS	crtI	NC_008702.1	1207554	1209134	D	Phytoene dehydrogenase (EC 1.14.99.-) (Phytoene desaturase). Phytoene dehydrogenase (phytoene desaturase) is an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene, TREMBL:Q8XYC4 (50% identity); SWISSPROT:P06108 (26% identity). InterPro (IPR008150): Bacterial-type phytoene dehydrogenase Pfam (Phytoene_dh): Phytoene dehydrogenase related enzyme.; High confidence in function and specificity; phytoene dehydrogenase	1207554..1209134	Azoarcus sp. BH72	4606698
YP_932624.1	CDS	azo1120	NC_008702.1	1209318	1210130	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8XYC0 (36% identity); TREMBL:Q9EX74 (34% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short chain dehydrogenase	complement(1209318..1210130)	Azoarcus sp. BH72	4608536
YP_932625.1	CDS	azo1121	NC_008702.1	1210127	1210732	R	This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoatesynthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, TREMBL:Q9HZE2 (34% identity); TREMBL:Q8XSM9 (39% identity). Pfam (PF00857): Isochorismatase family.; Family membership; isochorismatase family protein	complement(1210127..1210732)	Azoarcus sp. BH72	4606699
YP_932626.1	CDS	carBa1	NC_008702.1	1210885	1211421	R	Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. The beta subunit is may be responsible for the substrate specificity of the enzyme. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzene 12-dioxygenase beta subunit (EC 1.14.12.3), involved in benzoate degradation.Degradation of benzoate to 2-hydro-12-dihydroxybenzoate (dhb).; Conserved hypothetical protein; putative dioxygenase, hydroxylase small subunit	complement(1210885..1211421)	Azoarcus sp. BH72	4606700
YP_932627.1	CDS	carBb1	NC_008702.1	1211408	1212763	R	Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. 81% simialr to a Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by Pseudomonas resinovorans sp. strain CA10. TREMBL:Q8GI28 InterPro:IPR005806; Rieske_reg.IPR001663; Ring_hydroxyl_A. Pfam:PF00355; Rieske; 1. PF00848; Ring_hydroxyl_A; 1.; High confidence in function and specificity; putative dioxygenase hydroxylase large subunit	complement(1211408..1212763)	Azoarcus sp. BH72	4608416
YP_932628.1	CDS	vanB1	NC_008702.1	1212783	1213730	R	Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 40% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. InterPro: NADH:cytochrome b5 reductase (CBR)(IPR001834); Ferredoxin (IPR001041); Oxidoreductase FAD and NAD(P) binding domain (IPR001433) Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership; vanillate O-demethylase oxidoreductase	complement(1212783..1213730)	Azoarcus sp. BH72	4608418
YP_932629.1	CDS	azo1125	NC_008702.1	1214284	1215204	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W060 (64%) and to sprot|LIVH_ECOLI (24%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting eight Tmhelix.; Specificity unclear; ABC transporter permease	1214284..1215204	Azoarcus sp. BH72	4610090
YP_932630.1	CDS	livM2	NC_008702.1	1215207	1216199	D	Putative branched-chain amino acid transport permease Homology to livM of S. typhimurium of 28%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system signal peptide probable 9 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	1215207..1216199	Azoarcus sp. BH72	4606701
YP_932631.1	CDS	azo1127	NC_008702.1	1216196	1216945	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP binding domains are responsible for coupling the energy of ATP hydrolysis to conformational changes in the ransmembrane domains. Similar to trembl|Q7W058 (49%) and to sprot|LIVG_ECOLI (39%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily; Specificity unclear; ABC transporter ATP-binding protein	1216196..1216945	Azoarcus sp. BH72	4609159
YP_932632.1	CDS	azo1128	NC_008702.1	1216942	1217658	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7W057 (65%) and to trembl|Q84HI4 (49%). Smart (SM00382): ATPase superfamily Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; ABC transporter ATP-binding protein	1216942..1217658	Azoarcus sp. BH72	4606702
YP_932633.1	CDS	azo1129	NC_008702.1	1217770	1218957	D	ABC transporter substrate binding proteins counts to the family of extracellular ligand binding proteins. It is a component of the high affinity amino acid transport system. Similar to trembl|Q83V39 (51%) and to trembl|Q7WF58 (49%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Function unclear; ABC transporter substrate-binding protein	1217770..1218957	Azoarcus sp. BH72	4606703
YP_932634.1	CDS	azo1130	NC_008702.1	1219045	1219530	R	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA	complement(1219045..1219530)	Azoarcus sp. BH72	4606704
YP_932635.1	CDS	azo1131	NC_008702.1	1219713	1220327	R	Conserved hypothetical protein. Homology to Daro03001685 of Dechloromonas aromatica of 46% (gi|41725028|ref|ZP_00151838.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1219713..1220327)	Azoarcus sp. BH72	4606705
YP_932636.1	CDS	clpA	NC_008702.1	1220421	1222703	R	ATP-dependent Clp protease ATP-binding subunit clpA. Homology to clpA of E. coli of 63% (sprot|CLPA_ECOLI). ATP-dependent specificity component of the clpP protease. It directs the protease to specific substrates. The primary function of the clpA-clpP complex appears to be the degradation of unfolded or abnormal proteins. InterPro: AAA-protein (ATPases associated with various cellular activities)(IPR003959); AAA ATPase superfamily (IPR003593); Clp amino terminus (IPR004176); chaperonins clpA/B (IPR001270); Bacterial typeII secretion system protein E (IPR001482) Pfam: Clp amino ternimal domain; ATPase family associated with cellular activites no signal peptide no TMHs; High confidence in function and specificity; ATP-dependent Clp protease ATP-binding subunit clpA	complement(1220421..1222703)	Azoarcus sp. BH72	4606706
YP_932637.1	CDS	clpS	NC_008702.1	1222704	1223012	R	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS	complement(1222704..1223012)	Azoarcus sp. BH72	4608486
YP_932638.1	CDS	cspE	NC_008702.1	1223446	1223649	D	Cold-shock protein cspE, (When Escherichia coli is exposed to a temperature drop from 37 to 10 degrees centigrade, a 4-5 hour lag phase occurs, after which growth is resumed at a reduced rate. During the lag phase,the expression of around 13 proteins, which contain specific DNA-binding regions, is increased 2-10 fold. These so-called 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature.); High confidence in function and specificity; cold-shock protein	1223446..1223649	Azoarcus sp. BH72	4608490
YP_932639.1	CDS	rpmG	NC_008702.1	1223918	1224085	R	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33	complement(1223918..1224085)	Azoarcus sp. BH72	4608539
YP_932640.1	CDS	rpmB	NC_008702.1	1224147	1224383	R	required for 70S ribosome assembly; 50S ribosomal protein L28	complement(1224147..1224383)	Azoarcus sp. BH72	4609791
YP_932641.1	CDS	radC	NC_008702.1	1224488	1225165	R	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC	complement(1224488..1225165)	Azoarcus sp. BH72	4609786
YP_932642.1	CDS	dfp	NC_008702.1	1225220	1226419	D	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase	1225220..1226419	Azoarcus sp. BH72	4609691
YP_932643.1	CDS	dut	NC_008702.1	1226436	1226885	D	catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase	1226436..1226885	Azoarcus sp. BH72	4608619
YP_932644.1	CDS	azo1140	NC_008702.1	1226887	1227312	D	Conserved hypothetical MutT family protein. Homology to AGR_C_3368 of Agrobacterium tumefaciens of 33% (tremble:Q7CYF2). Pfam: NUDIX domain MutT is a small bacterial protein (~12-15Kd) involved in the GO system MEDLINE:1328155 responsible for removing an oxidatively damaged form of guanine (8-hydroxy- guanine or 7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with near equal efficiency, leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate, with the concomitant release of pyrophosphate. A short conserved N-terminal region of mutT (designated the MutT domain) is also found in a variety of other prokaryotic, viral and eukaryotic proteins. No signal peptide. No TMH; Family membership; mutT family protein	1226887..1227312	Azoarcus sp. BH72	4608657
YP_932645.1	CDS	soxF	NC_008702.1	1227315	1228592	R	Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership; sulfide dehydrogenase, flavoprtein subunit	complement(1227315..1228592)	Azoarcus sp. BH72	4606707
YP_932646.1	CDS	soxE	NC_008702.1	1228607	1228906	R	Putative sulfide dehydrogenase, cytochrome subunit. Homology to fccA of C. limicola of 26% (sprot|CYSD_CHLLT(SRS)) InterPro: Cytochrome c class I (IPR003088); cytochrome c class IC (IPR008168) Pfam: Cytochrome C signal peptide no TMHs; putative sulfide dehydrogenase, cytochrome subunit	complement(1228607..1228906)	Azoarcus sp. BH72	4609883
YP_932647.1	CDS	soxY	NC_008702.1	1229108	1229551	D	sulfur covalently-binding protein	1229108..1229551	Azoarcus sp. BH72	4609882
YP_932648.1	CDS	soxZ	NC_008702.1	1229562	1229873	D	Gene Function; High confidence in function and specificity; phosphodiesterase I	1229562..1229873	Azoarcus sp. BH72	4609885
YP_932649.1	CDS	aceK	NC_008702.1	1229883	1231652	R	catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase	complement(1229883..1231652)	Azoarcus sp. BH72	4609886
YP_932650.1	CDS	icd2	NC_008702.1	1232133	1234370	D	Isocitrate dehydrogenase [NADP]. Homology to icd2 of A. eutrophus of 80% (trembl|Q8KLU4) This monomeric type of isocitrate dehydrogenase is NADP-specific. It is an important enzyme of the TCA. Interpro: Isocitrate dehydrogenase NADP-dependent, monomeric type (IPR004436) Tigrfam: monomer-idh: isocitrate dehydrogenase NADP-dependent no singal peptide no TMHs; High confidence in function and specificity; isocitrate dehydrogenase	1232133..1234370	Azoarcus sp. BH72	4608261
YP_932651.1	CDS	icd1	NC_008702.1	1234547	1235824	D	Isocitrate dehydrogenase [NADP]. Homology to icd1 of A. eutropus of 75% (trembl|Q8KLU5) Isocitrate dehydrogenase is an important enzyme of the TCA which catalyzes the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+ Pfam: Isocitrate/isopropylmalate dehydrogenase Tigrfam: prok_nadp_idh: isocitrate dehydrogenase no signal peptide no TMHs; High confidence in function and specificity; isocitrate dehydrogenase	1234547..1235824	Azoarcus sp. BH72	4609065
YP_932652.1	CDS	azo1148	NC_008702.1	1236048	1236302	D	Conserved hypothetical membrane protein. Homology to ws0602 of W. succinogenes of 63% (trembl|Q7MSB5(SRS)) no domains predicted no singal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	1236048..1236302	Azoarcus sp. BH72	4609064
YP_932653.1	CDS	azo1149	NC_008702.1	1236315	1238120	D	Conserved hypothetical sodium:solute symporter. Homology to to ws0601 of W. succinogenes of 68% (trembl|Q7M9X9). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. InterPro: Sodium:solute symporter family (IPR001734) Tigrfam: sss: SSS sodium solute transporter superfamily no signal peptide 12 TMHs; Family membership; putative sodium:solute symporter	1236315..1238120	Azoarcus sp. BH72	4606708
YP_932654.1	CDS	azo1150	NC_008702.1	1238249	1238617	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No singal peptide 3 TMHs; hypothetical protein	1238249..1238617	Azoarcus sp. BH72	4606709
YP_932655.1	CDS	azo1151	NC_008702.1	1238632	1238925	R	Conserved hypothetical membrane protein. Homology to vv11244 of V. vulnificus of 42% (trembl|Q8DCZ3(SRS)) no domains predicted no signal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1238632..1238925)	Azoarcus sp. BH72	4606710
YP_932656.1	CDS	fusA1	NC_008702.1	1238922	1240967	R	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G	complement(1238922..1240967)	Azoarcus sp. BH72	4606711
YP_932657.1	CDS	azo1153	NC_008702.1	1241063	1242703	R	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 61%; Function unclear; major facilitator superfamily permease	complement(1241063..1242703)	Azoarcus sp. BH72	4608848
YP_932658.1	CDS	azo1154	NC_008702.1	1243088	1243822	R	Conserved hypothetical membrane protein. Homology to rsc2670 of R. solanacearum of 64% (tremble: Q8XWO5) Pfam: LrgB-like family The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance. no signal peptide 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1243088..1243822)	Azoarcus sp. BH72	4606712
YP_932659.1	CDS	azo1155	NC_008702.1	1243819	1244181	R	Conserved hypothetical membrane protein. This family is uncharacterised. It contains the protein LrgA that has been hypothesised to export murein hydrolases TREMBL:Q8XW06: 56% identity, 73% similarity InterPro:IPR005538; LrgA. Pfam: PF03788; LrgA; 1. ProDom: PD009239; LrgA Signal peptide present (Signal P predicted) TMH's 3 (TMHMM predicted); Conserved hypothetical protein; hypothetical protein	complement(1243819..1244181)	Azoarcus sp. BH72	4606713
YP_932660.1	CDS	azo1156	NC_008702.1	1244251	1245189	R	Conserved hypothetical membrane protein. Homology to Daro03002578 of Dechloromonas aromatica of 75% (gi|41723981|ref|ZP_00150871.1|(NBCI ENTREZ)). Has PF07670, Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for determining nucleoside specificity in the human CNT1 and CNT2 proteins. In the FeoB proteins, which are believed to be Fe2+ transporters, it includes the membrane pore region, so the function of this region is likely to be more general than just nucleoside specificity. This family may represent the pore and gate, with a wide potential range of specificity. Hence its name 'Gate'. no signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1244251..1245189)	Azoarcus sp. BH72	4606714
YP_932661.1	CDS	azo1157	NC_008702.1	1245583	1245789	R	Hypothetical secreted protein. Signal Peptide present. No good homolgous hits in the PDB. No TMHs No domains predicted.; hypothetical protein	complement(1245583..1245789)	Azoarcus sp. BH72	4606715
YP_932662.1	CDS	ncd2	NC_008702.1	1246197	1247258	D	TREMBL:Q9HWH9: 45% identity, 52% similarity 2-nitropropane dioxygenase (EC 1.13.11.32) (Nitroalkane oxidase) (2-NPD). CATALYZES THE OXYGENATIVE DENITRIFICATION OF VARIOUS ANIONIC NITROALKANES. InterPro: 2-nitropropane dioxygenase InterPro:IPR004136; 2nprop_dioxygen. IPR003009; FMN_enzyme. Pfam PF03060; NPD thiE: thiamine-phosphate pyrophosphoryl No transmembrane helices (TMHMM predicted); High confidence in function and specificity; 2-nitropropane dioxygenase	1246197..1247258	Azoarcus sp. BH72	4606716
YP_932663.1	CDS	aceB	NC_008702.1	1247367	1248971	R	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase	complement(1247367..1248971)	Azoarcus sp. BH72	4609346
YP_932664.1	CDS	azo1160	NC_008702.1	1248990	1249772	R	Conserved hypothetical membrane protein. Homology to mlr4286 of M. loti of 43% (trembl|Q98EE2) InterPro: IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices; Conserved hypothetical protein; hypothetical protein	complement(1248990..1249772)	Azoarcus sp. BH72	4608260
YP_932665.1	CDS	azo1161	NC_008702.1	1249955	1250920	D	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear; LysR family transcriptional regulator	1249955..1250920	Azoarcus sp. BH72	4606717
YP_932666.1	CDS	ttuD	NC_008702.1	1250865	1252127	R	Putative hydroxypyruvate reductase. Degrades an unidentified toxic product from the first step of tartrate degradation. Involved in the second step of the tartrate degradation pathway. 59% MOFRL.IPR005346; UPF0125. Pfam:PF05161; MOFRL; 1.PF03658; UPF0125; 1. Signal peptide present.; High confidence in function and specificity; hydroxypyruvate reductase	complement(1250865..1252127)	Azoarcus sp. BH72	4606718
YP_932667.1	CDS	gip	NC_008702.1	1252153	1252941	R	Hydroxypyruvate isomerase (EC 5.3.1.22).Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).Belongs to the hyi family. 52%; High confidence in function and specificity; putative hydroxypyruvate isomerase	complement(1252153..1252941)	Azoarcus sp. BH72	4610047
YP_932668.1	CDS	azo1164	NC_008702.1	1253717	1254214	D	Conserved hypothetical protein. Homology to ORF153 of Rubrivivax gelatinosus of 48% (gi|55832787|gb|AAV66902.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1253717..1254214	Azoarcus sp. BH72	4608878
YP_932669.1	CDS	lctP	NC_008702.1	1254523	1256169	R	L-lactate permease. Homology to lctP of E. coli of 72% (sprot|LLDP_ECOLI) Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity). Tigrfam: lctP: L-lactate transport Pfam: L-lactate permease signal peptide 12 TMHs; High confidence in function and specificity; LctP protein	complement(1254523..1256169)	Azoarcus sp. BH72	4606719
YP_932670.1	CDS	azo1166	NC_008702.1	1256528	1259305	R	Conserved hypothetical iron-sulfur binding oxidase. Homology to pa4772 of P. aeruginosa of 53% (pir|H83050) InterPro: FAD linked oxidase C-terminal (IPR004413) Pfam: FAD binding domain ; Fad linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership; iron-sulfur binding oxidase	complement(1256528..1259305)	Azoarcus sp. BH72	4609124
YP_932671.1	CDS	azo1167	NC_008702.1	1259517	1260968	R	Conserved hypothetical iron-sulfur protein. Homology to cv3028 of C. violaceum of 68% (trembl|Q7NTM6) Tigrfam: TIGR00273: iron-sulfur cluster binding protein Pfam: 4Fe-4S binding domain no TMHs no signal peptide; Conserved hypothetical protein; iron-sulfur protein	complement(1259517..1260968)	Azoarcus sp. BH72	4606720
YP_932672.1	CDS	azo1168	NC_008702.1	1260965	1261639	R	Conserved hypothetical protein. Homology to DVU1781 of D.vulgaris of 45% (tremble:Q72B57). Has PF02589 DUF162 domain:Uncharacterized ACR, YkgG family. No signal peptide or TMH reported present.; hypothetical protein	complement(1260965..1261639)	Azoarcus sp. BH72	4606721
YP_932673.1	CDS	azo1169	NC_008702.1	1261636	1262442	R	Conserved hypothetical protein. Homologyt to nma1648 of N. meiningitidis of 55% (trembl|Q825P5) InterPro: Domain of unknown function DUF224 (IPR004017) Pfam: Domain of unknown function no signal no TMHS; hypothetical protein	complement(1261636..1262442)	Azoarcus sp. BH72	4606722
YP_932674.1	CDS	lldR	NC_008702.1	1262710	1263492	D	Putative L-lactate dehydrogenase operon regulatory protein,; High confidence in function and specificity; L-lactate dehydrogenase operon regulatory protein	1262710..1263492	Azoarcus sp. BH72	4606723
YP_932675.1	CDS	azo1171	NC_008702.1	1264770	1265240	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide. no TMH; hypothetical protein	1264770..1265240	Azoarcus sp. BH72	4609166
YP_932676.1	CDS	azo1172	NC_008702.1	1265498	1265653	D	Conserved hypothetical protein. Homology to the N-terminus of NE0717 of Nitrosomonas europaea of 56% (tremble:Q82WG3). Pfam: Cold shock protein domain RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. No signal peptide. No TMHs; hypothetical protein	1265498..1265653	Azoarcus sp. BH72	4606724
YP_932677.1	CDS	azo1173	NC_008702.1	1265650	1266129	D	Conserved hypothetical membrane protein. Homology to the C-terminus of ne0717 of N. europaea of 57% (trembl|Q82WG3). Pfam: Protein of unknown function (DUF1294). No signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	1265650..1266129	Azoarcus sp. BH72	4606725
YP_932678.1	CDS	azo1174	NC_008702.1	1266287	1266538	D	Hypothetical protein. No homology to the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	1266287..1266538	Azoarcus sp. BH72	4606726
YP_932679.1	CDS	nirB	NC_008702.1	1266596	1269127	D	Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4). 76% EGF_like.IPR001327; FAD_pyr_redox. IPR007419;Fer2_BFD.IPR006066; Nir_Si.IPR006067; Nir_Sir_4Fe4S. IPR005117; NiR_SiR_beta_fer. IPR001100; Pyr_redox. Pfam: PF04324; Fer2_BFD; 1.PF01077; NIR_SIR; 1.PF03460; NIR_SIR_ferr; 1. PF00070; Pyr_redox; 1. In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center.; High confidence in function and specificity; nitrite reductase (NAD(P)H) large subunit	1266596..1269127	Azoarcus sp. BH72	4606727
YP_932680.1	CDS	nirD	NC_008702.1	1269149	1269487	D	Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4). REQUIRED FOR ACTIVITY OF THE REDUCTASE. 66% simialr to the nirD protein from R. solanacearum,a probable nitrite reductase NADPH (small subunit) oxidoreductase [EC:1.7.1.4]. TREMBL:Q8XQK3. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit In E.coli, the NADH-dependent nitrite reductase catalyzes the six-electron reduction of nitrite to ammonia and also catalyzes the two-electron reduction of hydroxylamine to ammonia. The enzyme is a FAD-flavoprotein, and also contains a siroheme and one 2Fe-2S center.; Conserved hypothetical protein; nitrite reductase small subunit	1269149..1269487	Azoarcus sp. BH72	4609380
YP_932681.1	CDS	nirC	NC_008702.1	1269519	1270331	D	76% For/Nit_transpt. Pfam: PF01226; Form_Nir_trans; 1. In E. coli, NirC is a putative nitrite transporter which is a member of the FNT family of formate and nitrite transporters. The nirC gene is located in the nir operon which codes for a NADH-dependent nitrite reductase. NirC may function to import nitrite as a substrate for this enzyme complex. The nir operon is anaerobically expressed and is repressed by oxygen. TMhelix:6; High confidence in function and specificity; putative nitrite transporter	1269519..1270331	Azoarcus sp. BH72	4609382
YP_932682.1	CDS	azo1178	NC_008702.1	1270372	1272093	D	Putative serin/threonin protein kinase,; Family membership; putative serine/threonine protein kinase	1270372..1272093	Azoarcus sp. BH72	4609381
YP_932683.1	CDS	allA	NC_008702.1	1272191	1272715	R	High confidence in function and specificity; ureidoglycolate hydrolase	complement(1272191..1272715)	Azoarcus sp. BH72	4606728
YP_932684.1	CDS	alc	NC_008702.1	1272715	1273755	R	catalyzes the formation of S-ureidoglycolate and urea from allantoate; allantoicase	complement(1272715..1273755)	Azoarcus sp. BH72	4608304
YP_932685.1	CDS	azo1181	NC_008702.1	1274116	1275063	R	Polysaccharide deacetylase family protein.This family of polysaccharide deacetylases includes NodB(nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase.It also includes chitin deacetylase from yeast,and endoxylanases which hydrolyses glucosidic bonds in xylan. 62% Polysac_deacet. Pfam:PF01522; Polysacc_deac_1. TIGR:PP4286.; Function unclear; deacetylase	complement(1274116..1275063)	Azoarcus sp. BH72	4608292
YP_932686.1	CDS	azo1182	NC_008702.1	1275084	1275611	R	Conserved hypothetical protein. Homology to RS01483 of R.solanacearum of 55% (tremble:Q8XXJ2). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1275084..1275611)	Azoarcus sp. BH72	4606729
YP_932687.1	CDS	azo1183	NC_008702.1	1275648	1276844	R	Conserved hypothetical membrane protein. Homology to RS01489 of Ralstonia solanacearum of 50% (trembl|Q8XXJ8(SRS)) Has PF06181:Protein of unknown function (DUF989);This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide 8 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1275648..1276844)	Azoarcus sp. BH72	4606730
YP_932688.1	CDS	azo1184	NC_008702.1	1276863	1277213	R	Conserved hypothetical transthyretin. Homology to pa1518 of P. aeruniosa of 62% (sprot|YF18_PSEAE) InterPro: Transthyretin precursor (IPR000895) Pfam: Transthyretin precursor no signal peptide no TMHs; Conserved hypothetical protein; putative transthyretin	complement(1276863..1277213)	Azoarcus sp. BH72	4606731
YP_932689.1	CDS	pip	NC_008702.1	1277327	1278304	R	TREMBL:Q8PC98: 42% identity, 54% similarity. Proline iminopeptidase (EC 3.4.11.5) (Prolyl aminopeptidase) (PAP). SPECIFICALLY CATALYZES THE REMOVAL OF N-TERMINAL PROLINE RESIDUES FROM PEPTIDES (BY SIMILARITY). InterPro:IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR002410; Peptidase_S33. IPR005944; Pept_S33. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; TIGRFAMs: TIGR01249; pro_imino_pep_1 TIGR00149: conserved hypothetical protein; Specificity unclear; proline iminopeptidase	complement(1277327..1278304)	Azoarcus sp. BH72	4606732
YP_932690.1	CDS	azo1186	NC_008702.1	1278781	1279233	D	hypothetical protein	1278781..1279233	Azoarcus sp. BH72	4609582
YP_932691.1	CDS	pqqB	NC_008702.1	1279714	1280628	D	possibly involved in transport of pyrroloquinoline quinone transport; pyrroloquinoline quinone biosynthesis protein PqqB	1279714..1280628	Azoarcus sp. BH72	4606733
YP_932692.1	CDS	pqqC	NC_008702.1	1280664	1281455	D	Required in the synthesis of PPQ, but its exact function is unknown; pyrroloquinoline quinone biosynthesis protein PqqC	1280664..1281455	Azoarcus sp. BH72	4609618
YP_932693.1	CDS	pqqD	NC_008702.1	1281634	1281900	D	Coenzyme PQQ synthesis protein D .This family contains several bacterial coenzyme PQQ synthesis protein D (PqqD) sequences. This protein is required for coenzyme pyrrolo-quinoline-quinone (PQQ) biosynthesis. 65% similarity with Klebsiella pneumoniae and 80%; Family membership; PqqD protein	1281634..1281900	Azoarcus sp. BH72	4609619
YP_932694.1	CDS	pqqE	NC_008702.1	1281902	1283056	D	Coenzyme PQQ synthesis protein E (Pyrroloquinoline quinone biosynthesis protein E).PART OF THE PQQ OPERON. Q88QV8: 58% identity, 74% similarity with Klebsiella pneumoniae InterProIPR000385, InterProIPR007197,PfamPF04055, SMARTSM00729, InterProIPR006638 cofactor:iron-sulfur cluster (potential). pathway:pyrroloquinoline quinone (pqq) biosynthesis. similarity: belongs to the radical sam superfamily, pqqE family TIGR PP0376; HAMAP MF_00660; Pfam PF04055; Radical_SAM; PROSITE: PS01305; MOAA_NIFB_PQQE; High confidence in function and specificity; pyrroloquinoline quinone biosynthesis protein PqqE	1281902..1283056	Azoarcus sp. BH72	4609620
YP_932695.1	CDS	azo1191	NC_008702.1	1283387	1283563	R	Hypothetical protein. Has very bad homology with hits in the database. No Signficant motifs, domains or Signal peptide known to be present.; hypothetical protein	complement(1283387..1283563)	Azoarcus sp. BH72	4610020
YP_932696.1	CDS	azo1192	NC_008702.1	1283668	1284468	R	Conserved hypothetical protein. Homology to XAC0112 of X.axonopodis of 44% (trembl:Q8PR54). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1283668..1284468)	Azoarcus sp. BH72	4606734
YP_932697.1	CDS	hppD	NC_008702.1	1284477	1285598	R	Probable 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase). Homology to hppD of Pseudomonas sp. of 56% (pir|S21209) Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2. Pfam: Glaxolase/Bleomycin resistance protein no signal peptide no TMHs; Family membership; 4-hydroxyphenylpyruvate dioxygenase	complement(1284477..1285598)	Azoarcus sp. BH72	4606735
YP_932698.1	CDS	azo1194	NC_008702.1	1286022	1287257	D	Permease member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 2A0121: H+ Antiporter protein 24% similarity to NorA who confer relatively high resistance to hydrophilic quinolones such as norfloxacin, enoxacin, ofloxacin, and ciprofloxacin in S. aureus. 20% similarity to TapA a multidrug efflux pump wich confers low level of resistance to aminoglycosides and tetracycline in Mycobaterium fortuitum and M. tuberculosis.; Specificity unclear; putative integral membrane efflux protein	1286022..1287257	Azoarcus sp. BH72	4609025
YP_932699.1	CDS	argD	NC_008702.1	1287319	1288497	D	DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase	1287319..1288497	Azoarcus sp. BH72	4606736
YP_932700.1	CDS	azo1196	NC_008702.1	1288769	1289806	R	Conserved hypothetical protein. Homology to ypo3484 of y. pestis of 60% (trembl|Q8ZBD2). Pfam: Luciferase-like monooxygenase. no signla peptide no TMHs; hypothetical protein	complement(1288769..1289806)	Azoarcus sp. BH72	4608340
YP_932701.1	CDS	azo1197	NC_008702.1	1289811	1290620	R	similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; putative GTP cyclohydrolase	complement(1289811..1290620)	Azoarcus sp. BH72	4606737
YP_932702.1	CDS	dxs	NC_008702.1	1290707	1292566	R	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase	complement(1290707..1292566)	Azoarcus sp. BH72	4606738
YP_932703.1	CDS	ispA	NC_008702.1	1292594	1293496	R	Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity; geranyltranstransferase	complement(1292594..1293496)	Azoarcus sp. BH72	4608659
YP_932704.1	CDS	xseB	NC_008702.1	1293493	1293747	R	Probable Probable exodeoxyribonuclease VII small subunit . InterPro: Exonuclease VII small subunit.; Function unclear; exodeoxyribonuclease VII	complement(1293493..1293747)	Azoarcus sp. BH72	4609094
YP_932705.1	CDS	alcE	NC_008702.1	1293877	1294977	D	AlcE: iron-sulfur-containing dioxygenases, probably involved in alcaligin biosynthesis pathway in Bordetella species. Putative iron-sulfure protein involved in aromatic compounds degradations. Choline monooxygenase chloroplast precursor (EC 1.14.15.7). Catalyzes the first step of the osmoprotectant glycine betaine synthesis. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit hypA: hydrogenase expression/formation pr; Function unclear; putative iron-sulfur protein	1293877..1294977	Azoarcus sp. BH72	4610130
YP_932706.1	CDS	ispH	NC_008702.1	1295352	1296290	R	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase	complement(1295352..1296290)	Azoarcus sp. BH72	4608293
YP_932707.1	CDS	slpA	NC_008702.1	1296320	1296748	R	Putative peptidyl-prolyl cis-trans isomerase. Homology to slpA of E. coli of 39% (sprot|FKBX_ECOLI) Accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)(IPR001179) Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMHs; Family membership; putative peptidyl-prolyl cis-trans isomerase	complement(1296320..1296748)	Azoarcus sp. BH72	4609189
YP_932708.1	CDS	lspA	NC_008702.1	1296745	1297275	R	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase	complement(1296745..1297275)	Azoarcus sp. BH72	4609872
YP_932709.1	CDS	ileS	NC_008702.1	1297268	1300066	R	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase	complement(1297268..1300066)	Azoarcus sp. BH72	4609182
YP_932710.1	CDS	ribF	NC_008702.1	1300081	1301079	R	Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthetase)]. ribF: riboflavin biosynthesis protein R; High confidence in function and specificity; riboflavin kinase/FMN adenylyltransferase	complement(1300081..1301079)	Azoarcus sp. BH72	4606739
YP_932711.1	CDS	azo1207	NC_008702.1	1301459	1301782	D	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	1301459..1301782	Azoarcus sp. BH72	4609724
YP_932712.1	CDS	gloB1	NC_008702.1	1301779	1302555	D	Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II). Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid. Zn dependent Hydrolase belonging to glyoxalase II family of proteins. Presence of KOW motif,and PA domain.Presence of signal peptide. probably functioning as Carbamoylphosphate synthase L chain. 50% identity and 60% similarity to Bordetella pertussis hydrolase. InterPro: Metallo-beta-lactamase superfamily gidA: glucose-inhibited division protein; Family membership; hydroxyacylglutathione hydrolase	1301779..1302555	Azoarcus sp. BH72	4606740
YP_932713.1	CDS	azo1209	NC_008702.1	1302969	1303301	D	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1302969..1303301	Azoarcus sp. BH72	4608909
YP_932714.1	CDS	azo1210	NC_008702.1	1303298	1304290	D	TREMBLnew:CAE26305: 46% identity, 65% similarity. sprot:YJIA_ECOLI, 33% identity, 55% similarity Hypothetical protein. Pfam:cobW: Cobalmine synthesis protein; ABC_tran TIGRFAM: MMR_HSR1- GTPASE of unknown function InterPro: Cobalamin synthesis protein/P47K mobB: molybdopterin-guanine dinucleotid; Conserved hypothetical protein; putative GTPase	1303298..1304290	Azoarcus sp. BH72	4606741
YP_932715.1	CDS	azo1211	NC_008702.1	1304287	1305360	D	Conserved hypothetical protein. Homology bll7767 of B. japonicum of 30% (trembl|Q89CN0) Pfam: WD domain, G-beta repeat no signal peptide no TMHs; hypothetical protein	1304287..1305360	Azoarcus sp. BH72	4606742
YP_932716.1	CDS	azo1212	NC_008702.1	1305397	1305612	D	Conserved hypothetical protein. Homology to Rsph03000178 of Rhodobacter sphaeroides of 37%. No domains predicted. No signal peptide. No TMHs; hypothetical protein	1305397..1305612	Azoarcus sp. BH72	4606743
YP_932717.1	CDS	qbdB1	NC_008702.1	1305750	1306688	D	Conserved hypothetical secreted protein. Homology to qbdB of Pseudomonas putida of 50% (gi|22779360|dbj|BAC15558.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	1305750..1306688	Azoarcus sp. BH72	4606744
YP_932718.1	CDS	azo1214	NC_008702.1	1306817	1307347	D	Conserved hypothetical membrane protein. Homology to Rgel02003151 of Rubrivivax gelatinosus of 37% (gi|47572524|ref|ZP_00242567.1|(NBCI ENTREZ)). PF06496,Protein of unknown function (DUF1097);IPR009476;This family consists of several bacterial putative membrane proteins. signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	1306817..1307347	Azoarcus sp. BH72	4609677
YP_932719.1	CDS	mntC2	NC_008702.1	1307593	1308540	D	Part of the ABC transporter complex mntABC involved in manganese uptake. 28% Similar to the putative periplasmic-binding protein MntC precursor in N gonorrhoaeae, also involved in the resistance to oxidative stress. TREMBL:Q9F4F6 InterPro:IPR006128; Lipoprotein_4.IPR006127; SBP_bac_9. Pfam:PF01297; SBP_bac_9; 1. Signal peptide present.TMHelix:1 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.This protein also could act as an adhesin which is involved on adherence to extracellular matrix.; High confidence in function and specificity; putative periplasmic solute binding protein	1307593..1308540	Azoarcus sp. BH72	4606745
YP_932720.1	CDS	mntA2	NC_008702.1	1308560	1309357	D	Manganese transport system ATP-binding protein mntA. This protein is probably a component of a manganese permease a binding protein-dependent ATP-driven transport system (mntABC). Probably responsible for energy coupling to the transport system. 40% AAA_ATPase.IPR003439,AAA ATPase superfamily; ABC_transporter. Pfam: PF00005; ABC_tran; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system ATP-binding protein	1308560..1309357	Azoarcus sp. BH72	4609240
YP_932721.1	CDS	mntB2	NC_008702.1	1309369	1310265	D	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. 28% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. TmHelix:8 This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system permease	1309369..1310265	Azoarcus sp. BH72	4609235
YP_932722.1	CDS	mntB3	NC_008702.1	1310262	1311221	D	Part of the ABC transporter complex mntABC involved in manganese import. Probably responsible for the translocation of the substrate across the membrane. Similar to the permease, MntB in Synechocystis 6803. 30% IPR001626; ABC_transpt3. Pfam; PF00950; ABC-3; 1. This operon probably is also involved in other cations uptake like Fe,Cu and Zn.; High confidence in function and specificity; putative manganese transport system permease	1310262..1311221	Azoarcus sp. BH72	4609237
YP_932723.1	CDS	azo1219	NC_008702.1	1311744	1313414	D	Conserved hypothetical aromatic/alkene monooxygenase, subunit alpha Homology to blr3677 of B. japonicum (trembl|Q89P06(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). InterPro:IPR003430 Pfam: Methane/Phenol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear; aromatic/alkene monooxygenase subunit alpha	1311744..1313414	Azoarcus sp. BH72	4609238
YP_932724.1	CDS	azo1220	NC_008702.1	1313496	1314539	D	Conserved hypothetical aromatic/alkene monooxygenase, subunit gamma. Homology to blr3678 of B. japonicum of 60% (trembl|Q89P05(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Phenol hydroxylase reductase family (IPR001221); Oxidoredutase FAD and NAD(P)-binding domain (IPR000134); NADH:cytochrome b5 reductase (CBR) (IPR000134) Pfam: 2Fe-2S iron-sulfur cluster binding domain; oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain no signal peptide no TMHs; Specificity unclear; aromatic/alkene monooxygenase subunit gamma	1313496..1314539	Azoarcus sp. BH72	4606746
YP_932725.1	CDS	azo1221	NC_008702.1	1314604	1315695	D	Conserved hypothetical aromatic/alkene monooxygenase, subunit beta Homology to blr3679 of B. japonicum of 53% (trembl|Q89P04(SRS) Bacterial aromatic/alkene monooxygenase is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives (like methane and toulene). Interpro: Methane/Penol/Toluene hydroxylase (IPR003430) Pfam: Methane/Penol/Toluene hydroxylase (PF02332) no signal peptide no TMHs; Specificity unclear; aromatic/alkene monooxygenase subunit beta	1314604..1315695	Azoarcus sp. BH72	4606747
YP_932726.1	CDS	dmpM	NC_008702.1	1315744	1316100	D	Phenol hydroxylase P2 protein (Phenol 2-monooxygenase P2 component)68% similarity to SWISSPROT:P19731,Pseudomonas sp DmpM or Phenol hydroxylase component P2, this protein lacks redox co-factors and is required for optimal turnover of Phenol hydroxylase . Phenol hydroxylase catabolises phenol and some of its methylated derivatives in the first step of phenol biodegradation, and is required for growth on phenol. The multicomponent enzyme is made up of P0, P1, P2, P3, P4 and P5 polypeptides. Pfam:PF02406, InterPro:IPR003454 91% similarity with hypothetical protein Rgel01002820 [Rubrivivax gelatinosus PM1] NO Signal Peptide No TMH's. MmoB/DmpM family; High confidence in function and specificity; phenol 2-monooxygenase	1315744..1316100	Azoarcus sp. BH72	4606748
YP_932727.1	CDS	groEL	NC_008702.1	1316323	1317960	D	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; chaperonin GroEL	1316323..1317960	Azoarcus sp. BH72	4608629
YP_932728.1	CDS	azo1224	NC_008702.1	1318051	1318197	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	1318051..1318197	Azoarcus sp. BH72	4608938
YP_932729.1	CDS	azo1225	NC_008702.1	1318385	1320445	D	Some bacterial regulatory proteins activate the expression of genes from promoters recognized by core RNA polymerase associated with the alternative sigma-54 factor. These have a conserved domain of about 230 residues involved in the ATP-dependent interaction with sigma-54, TREMBL:Q8RM05 (41% identity); TREMBL:Q880V5 (32% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; Family membership; sigma-54 dependent transcriptional regulator	1318385..1320445	Azoarcus sp. BH72	4606749
YP_932730.1	CDS	lguL	NC_008702.1	1320918	1321319	D	Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Similar to trembl|Q8YEJ0 (61%), to trembl|Q8DB12 (58%) and to trembl|Q8UCM7 (52%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase; Specificity unclear; lactoylglutathione lyase	1320918..1321319	Azoarcus sp. BH72	4606750
YP_932731.1	CDS	azo1227	NC_008702.1	1321373	1321966	D	Conserved hypothetical secreted protein. Homology to blr7490 of B. japonicum of 31% (trembl|Q89DE9(SRS)). No domains predicted. No TMHs Signal peptide present; Conserved hypothetical protein; hypothetical protein	1321373..1321966	Azoarcus sp. BH72	4609136
YP_932732.1	CDS	gdhAlpha1	NC_008702.1	1321992	1323557	D	Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 29% (trembl|Q8GQE7) InterPro: NAD binding site (IPR000205) Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear; putative glucose dehydrogenase subunit alpha	1321992..1323557	Azoarcus sp. BH72	4606751
YP_932733.1	CDS	azo1229	NC_008702.1	1323688	1324407	D	Hypothetical secreted protein. No good homology with hits in the database. Signal peptide present. No TMHs. No domains predicted; hypothetical protein	1323688..1324407	Azoarcus sp. BH72	4608873
YP_932734.1	CDS	azo1230	NC_008702.1	1324442	1324726	R	Conserved hypothetical membrane protein, 40% identity (49% Similarity) to TrEMBL;Q6D7F7. Signa P reporting Signal peptide present. TMHMM2 reporting 2 TMH's present.; Conserved hypothetical protein; hypothetical protein	complement(1324442..1324726)	Azoarcus sp. BH72	4606752
YP_932735.1	CDS	cydB	NC_008702.1	1324874	1326016	R	Cytochrome D ubiquinol oxidase subunit II (EC 1.10.3.-) (Cytochrome BD-I oxidase subunit II). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. Tigrfam: cydB: cytochrome d ubiquinol oxidase subunit II Pfam: cytochrome oxidase subunit II no signal peptide 8 TMHs; High confidence in function and specificity; cytochrome bd type terminal oxidase subunit II	complement(1324874..1326016)	Azoarcus sp. BH72	4606753
YP_932736.1	CDS	cydA	NC_008702.1	1326028	1327596	R	Probable cytochrome bd type terminal oxidase,subunit I. Homology to cydA of A. vinelandii of 67% (sprot|CYDA_AZOVI). Cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake. Members of this family are integral membrane proteins and contain a protoheame IX center B558. It may play an important role in microaerobic nitrogen fixation. InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no singal peptide 9 TMHs; High confidence in function and specificity; cytochrome bd type terminal oxidase subunit I	complement(1326028..1327596)	Azoarcus sp. BH72	4608553
YP_932737.1	CDS	azo1233	NC_008702.1	1327586	1327813	R	Hypothetical membrane protein. no homology to to the data bank. no domains predicted. no signal peptide. 1 TMHs; hypothetical protein	complement(1327586..1327813)	Azoarcus sp. BH72	4608552
YP_932738.1	CDS	azo1234	NC_008702.1	1327954	1329348	D	Probable ranscriptional regulator,; Specificity unclear; transcriptional regulator	1327954..1329348	Azoarcus sp. BH72	4606754
YP_932739.1	CDS	petA2	NC_008702.1	1329607	1330194	D	Ubiquinol-cytochrome C reductase iron-sulfur protein. Homology to petA of R. gelantinosus of 60% (trembl|Q93SY7). Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Pfam: Riedke [2Fe-2S] domain no TMHs signal peptide; High confidence in function and specificity; ubiquinol-cytochrome C reductase iron-sulfur protein	1329607..1330194	Azoarcus sp. BH72	4606755
YP_932740.1	CDS	azo1236	NC_008702.1	1330265	1332022	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q88H94 (52% identity); TREMBL:Q9RXZ1 (29% identity); SWISSPROT:Q9WYC4 (25% identity). Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting six transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; ABC transporter permease and ATP-binding protein	1330265..1332022	Azoarcus sp. BH72	4609525
YP_932741.1	CDS	subC	NC_008702.1	1332019	1332723	D	Subtilisin Savinase precursor, 36% identity to SwissProt; P29600. Has PF00082, Subtilase family;IPR000209, Pept_S8_S53;Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see Trypsin). Structure is an alpha/beta fold containing a 7-stranded parallel beta sheet, order 2314567. PROSITE;) PS00136; SUBTILASE_ASP; 1. PS00137; SUBTILASE_HIS; 1. PS00138; SUBTILASE_SER; 1.; subtilisin	1332019..1332723	Azoarcus sp. BH72	4606756
YP_932742.1	CDS	azo1238	NC_008702.1	1332713	1334038	D	Conserved hypothetical secreted protein. Homology to ebA2217 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA2217(KEGG)). C-terminus is not homolog to COG0644. signal peptide present. no TMHS.; Conserved hypothetical protein; hypothetical protein	1332713..1334038	Azoarcus sp. BH72	4609903
YP_932743.1	CDS	qhpA	NC_008702.1	1334490	1336076	D	Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpA of P.putida of 50% (gi|18655859|pdb|1JMZ|A(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain, alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. Has PF00034, Cytochromes c (cytC). Interpro (IPR009111) Quinohemoprotein amine dehydrogenase, alpha chain, domain 3. Signal peptide present. No TMHs.; High confidence in function and specificity; quinohemoprotein amine dehydrogenase subunit alpha	1334490..1336076	Azoarcus sp. BH72	4606757
YP_932744.1	CDS	qhpX	NC_008702.1	1336144	1337574	D	Conserved hypothetical qinohemoprotein amine dehydrogenase, unknown subunit. Homology to P. putida of 71% (gi|16950513|dbj|BAB72009.1|(NBCI ENTREZ)). InterPro:IPR000385; MoaA_NifB_PqqE. IPR007197; Radical_SAM. Pfam:PF04055; Radical_SAM. No signal peptide. No TMHs; Family membership; putative qinohemoprotein amine dehydrogenase	1336144..1337574	Azoarcus sp. BH72	4609679
YP_932745.1	CDS	qhpC	NC_008702.1	1337576	1337902	D	Probable quinohemoprotein amine dehydrogenase,gamma subunit. Homology to qhnDH of P. putida of 54% (sprot|QADG_PSEPK(SRS). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain,alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. no domains predicted. no signal peptide. no TMHs; High confidence in function and specificity; quinohemoprotein amine dehydrogenase subunit gamma	1337576..1337902	Azoarcus sp. BH72	4609682
YP_932746.1	CDS	qhpB	NC_008702.1	1337920	1339065	D	Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpB of P.putida of 50% (gi|34809688|pdb|1PBY|B(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric enzyme containing alpha, beta and gamma chains encoded by separate genes. The alpha chain makes contact with both the beta and gamma chains. The small gamma chain forms three intra-chain cross-links via thioester bonds between cysteine and aspartic or glutamic acid residues, thereby encaging the cysteine tryptophylquinone cofactor. The largest chain, alpha, contains two heme c groups. The alpha chain is folded into four domains, domain 1 forming a diheme cytochrome. Domains 2, 3 and 4 are antiparallel beta-barrel structures. Interpro (IPR0011044) Quinoprotein amine dehydrogenase, beta chain-like. Signal peptide present. No TMHs.,; High confidence in function and specificity; quinohemoprotein amine dehydrogease subunit beta	1337920..1339065	Azoarcus sp. BH72	4609681
YP_932747.1	CDS	azo1243	NC_008702.1	1339138	1340523	R	Conserved hypothetical N-acetylmuramoyl-L-alanine amidase. Homology to amiC of R. solanaceraum of 50% (trembl|Q8XWD5) CELL-WALL HYDROLASE PROBABLY INVOLVED IN CELL-WALL HYDROLYSIS SEPTATION OR RECYCLING (BY SIMILARITY). Pfam: N-acetylmuramoyl-L-alanine amidase no signal peptide no TMHs; Family membership; N-acetylmuramoyl-L-alanine amidase	complement(1339138..1340523)	Azoarcus sp. BH72	4609680
YP_932748.1	CDS	azo1244	NC_008702.1	1340466	1340987	R	Conserved hypothetical protein having uncharacterised P-loop hydrolase, 47% Identity to TrEMBL;Q82WL4,Q63WN1. Has PF02367, Uncharacterised P-loop hydrolase UPF0079;IPR003442; This signature is found in a family of bacterial proteins, which contain a P-loop.; hypothetical protein	complement(1340466..1340987)	Azoarcus sp. BH72	4606758
YP_932749.1	CDS	azo1245	NC_008702.1	1341000	1342058	D	Conserved hypothetical electron transport protein. Homology to pa4950 of P. aeruginosa of 63% (trembl|Q9HUL4). Pfam: 4Fe-4S- binding domain Tigrfam: TIG00276: iron-sulfur cluster binding protein, putative no TMHs no signal peptide TIGR00276: iron-sulfur cluster binding pr; Conserved hypothetical protein; electron transport protein	1341000..1342058	Azoarcus sp. BH72	4606759
YP_932750.1	CDS	azo1246	NC_008702.1	1342145	1343311	R	Conserved hypothetical mandelate racemase. Homology to bll6730 of B. japonicum of 76% (trembl|Q89FH0) Mandelate racemase and muconate lactonizing enzyme are two bacterial enzymes involved in aromatic acid catabolism. They catalyze mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures. InterPro: Mandelate racemase/muconate lactonizing enzyme family (IPR001354) Pfam: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain; Specificity unclear; mandelate racemase	complement(1342145..1343311)	Azoarcus sp. BH72	4606760
YP_932751.1	CDS	azo1247	NC_008702.1	1343604	1344530	D	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear; LysR family transcriptional regulator	1343604..1344530	Azoarcus sp. BH72	4606761
YP_932752.1	CDS	nifY2	NC_008702.1	1344671	1345414	D	NifY-like protein. Homology to Daro03003760 of Dechloromonas aromatica of 65% (gi|46140358|ref|ZP_00203574.1|(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs.; Family membership; NifY protein	1344671..1345414	Azoarcus sp. BH72	4606762
YP_932753.1	CDS	azo1249	NC_008702.1	1345528	1345794	D	Hypothetical protein predicted by Glimmer/Critica. No homology to the data bank. No domains predicted. No signal peptide No TMHs; hypothetical protein	1345528..1345794	Azoarcus sp. BH72	4609377
YP_932754.1	CDS	azo1250	NC_008702.1	1345875	1346084	D	Conserved Hypotheitcal protein. Very strong consideration to be a homolog for SlyX protein. TrEMBL: Q7WMX4, 32% identity. Has PF04102|SlyX;(IPR007236):The SlyX protein has no known function. It is short less than 80 amino acids and is found close to the slyD gene. The SlyX protein has a conserved PPH(Y/W) motif at its C-terminus. The protein may be a coiled-coil structure. No Signal peptide present. No TMH present.; Family membership; hypothetical protein	1345875..1346084	Azoarcus sp. BH72	4606763
YP_932755.1	CDS	azo1251	NC_008702.1	1346107	1348047	R	Conserved hypothetical peptidase. Homology to cv0266 of C. violaceum of 58% (cvi:CV0266). InterPro: Peptidase family U32 Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership; peptidase	complement(1346107..1348047)	Azoarcus sp. BH72	4606764
YP_932756.1	CDS	azo1252	NC_008702.1	1348202	1348510	R	Conserved hypothetical membrane protein. Homology to XCC3430 of Xanthomonas campestris of 38% (trembl:Q8P5B1). Has PF04892, VanZ like family;IPR006976 ; This family contains several examples of the VanZ protein,but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin, showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal peptide. 2 TMHs.; Conserved hypothetical protein; hypothetical protein	complement(1348202..1348510)	Azoarcus sp. BH72	4606765
YP_932757.1	CDS	azo1253	NC_008702.1	1348736	1349905	D	Similar to the GdhB protein, a putative glucose dehydrogenase-B, periplasmic protein [EC:1.1.5.2], from Synechocystis. SPTR: P73001. Signal peptide:present; hypothetical protein	1348736..1349905	Azoarcus sp. BH72	4606766
YP_932758.1	CDS	azo1254	NC_008702.1	1349902	1351638	R	Conserved hypothetical signaling protein. Homology to Bcep02001865 of Burkholderia fungorum of 44% (gi|48787085|ref|ZP_00283167.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices (in signal peptide).; Conserved hypothetical protein; putative signaling protein	complement(1349902..1351638)	Azoarcus sp. BH72	4606767
YP_932759.1	CDS	potD	NC_008702.1	1351635	1352795	R	Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Similar to trembl|Q986V8 (37%). Pfam (PF01547): Bacterial extracellular solute-binding protein; Family membership; extracellular solute-binding protein	complement(1351635..1352795)	Azoarcus sp. BH72	4606768
YP_932760.1	CDS	azo1256	NC_008702.1	1352950	1355322	D	Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases).; Family membership; putative serine/threonine protein kinase	1352950..1355322	Azoarcus sp. BH72	4609598
YP_932761.1	CDS	azo1257	NC_008702.1	1355479	1356123	D	Conserved hypothetical protein. Homology to CV1784 of C.violaceum of 40% (tremble:Q7NX45). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1355479..1356123	Azoarcus sp. BH72	4606769
YP_932762.1	CDS	azo1258	NC_008702.1	1356239	1358347	D	hypothetical membrane protein no homology to entire proteins seven transmembrane domains predicted, no signal peptide predicted; Family membership; hypothetical protein	1356239..1358347	Azoarcus sp. BH72	4606770
YP_932763.1	CDS	pepD	NC_008702.1	1358370	1359830	D	Probable aminoacyl-histidine dipeptidase (EC 3.4.13.3) (Xaa-His dipeptidase) (X-His dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Peptidase D). Homology to pepD of E. coli of 44%. THIS DIPEPTIDASE HAS SPECIFICITY FOR THE UNUSUAL DIPEPTIDE BETA-ALANYL-L-HISTIDINE. InterPro: Peptidase family M20/M25/M40 (IPR002933) Pfam: Peptidase family M20/M25/M40 no signal peptide no TMHs; High confidence in function and specificity; aminoacyl-histidine dipeptidase	1358370..1359830	Azoarcus sp. BH72	4606771
YP_932764.1	CDS	azo1260	NC_008702.1	1359827	1360354	R	Conserved hypothetical protein. Homology to RPA1575 of R.palustris of 41% (tremble:Q6N9H4). Has PF04536:(IPR007621)Domain of unknown function (DUF477);This is a family of uncharacterised proteins. They are found in both eukarya and eubacteria. No TMHs. No signal peptide.; hypothetical protein	complement(1359827..1360354)	Azoarcus sp. BH72	4609520
YP_932765.1	CDS	azo1261	NC_008702.1	1360403	1361335	R	Conserved hypothetical membrane protein. Homology to Bll7266 of B. japonicum of 45% (trembel:Q89E21) InterPro:IPR007621; DUF477. Pfam:PF04536; DUF477 Signal peptide present (Signal P predicted). Presence of 2 transmembrane helices.; Conserved hypothetical protein; hypothetical protein	complement(1360403..1361335)	Azoarcus sp. BH72	4606772
YP_932766.1	CDS	lemA1	NC_008702.1	1361353	1361979	R	Putative lipoprotein [lemA],57 % identity (75% similarity) to TrEMBL;Q72TG3,TrEMBL;Q6N9H6(60% identity). No signl peptide or TMH present. Has PF04011:LemA family(IPR007156,lemA);The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular [1]. The exact molecular function of this protein is uncertain.; Conserved hypothetical protein; LemA family protein	complement(1361353..1361979)	Azoarcus sp. BH72	4606773
YP_932767.1	CDS	azo1263	NC_008702.1	1362162	1362374	D	Conserved yhpothetical protein. Homology to BP1565 of B.pertussis of 66% (tremble:Q7VY02) Has PF07311:Protein of unknown function (DUF1458)(IPR009923 );This family consists of several hypothetical bacterial proteins as well as one archaeal sequence Q9HPW4. Members of this family are typically of around 70 residues in length. The function of this family is unknown. No signal peptide or TMH present.; hypothetical protein	1362162..1362374	Azoarcus sp. BH72	4609125
YP_932768.1	CDS	azo1264	NC_008702.1	1362410	1363681	D	Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices.; putative transmembrane sensor protein	1362410..1363681	Azoarcus sp. BH72	4606774
YP_932769.1	CDS	azo1265	NC_008702.1	1363688	1363981	R	Hypothetical protein, 26% identity(49% similarity) to TrEMBL;Q8XT66. TrEMBL;Q7P1L8(34% identity). No domains,repeats, motifs or features present.; hypothetical protein	complement(1363688..1363981)	Azoarcus sp. BH72	4606775
YP_932770.1	CDS	dnaJ2	NC_008702.1	1364049	1365062	R	Putative chaperone protein dnaJ. homology to dnaJ of E. coli of 32% (sprot|DNAJ_ECOLI) Acts as a co-chaperone. Stimulates jointly with grpE the ATPase activity of dnaK (By similarity). Pfam: DnaJ domain, DnaJ central domain (4 repeats), DnaJ Cterminal region no singal peptide no TMHs; Family membership; putative chaperone protein DnaJ	complement(1364049..1365062)	Azoarcus sp. BH72	4606776
YP_932771.1	CDS	azo1267	NC_008702.1	1365220	1365705	D	Entry name TREMBL:Q7W380 Prim. accession # Q7W380 Identities = 111/150 (74%) InterPro IPR006683; Thioestr_supf. Pfam PF03061; 4HBT; 1. Prediction: Non-secretory protein Signal peptide probability: 0.179 Number of predicted TMHs: 0; Family membership; acyl-CoA thioester hydrolase	1365220..1365705	Azoarcus sp. BH72	4608635
YP_932772.1	CDS	azo1268	NC_008702.1	1365702	1365947	D	Conserved hypothetical protein. Homology to PBPRB0126 of Photobacterium profundum of 54% (trembl:Q6LL06). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1365702..1365947	Azoarcus sp. BH72	4606777
YP_932773.1	CDS	purT	NC_008702.1	1365959	1367140	R	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2	complement(1365959..1367140)	Azoarcus sp. BH72	4606778
YP_932774.1	CDS	azo1270	NC_008702.1	1367335	1368981	D	Probable Branched-chain amino acid aminotransferase (EC 2.6.1.42) (Transaminase B) (BCAT). thrC: threonine synthase.; Function unclear; hypothetical protein	1367335..1368981	Azoarcus sp. BH72	4609664
YP_932775.1	CDS	azo1271	NC_008702.1	1368995	1369639	R	Conserved hypothetical secreted protein. Homology to pa3214 of P. aeruginosa of 52% (trembl|Q9HZ26). Pfam: DUF330 signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	complement(1368995..1369639)	Azoarcus sp. BH72	4606779
YP_932776.1	CDS	azo1272	NC_008702.1	1369636	1370577	R	Conserved hypothetical secreted protein. Similar to TREMBL:Q9HZ27 (53% identity); TREMBL:Q88RI9 (46% identity); TREMBL:Q8PGP4 (33% identity). Pfam (PF02470): mce related protein. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(1369636..1370577)	Azoarcus sp. BH72	4606780
YP_932777.1	CDS	azo1273	NC_008702.1	1370579	1371361	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8PGP5 (60% identity); TREMBL:Q9PDS7 (57% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear; putative ABC transporter ATP-binding protein	complement(1370579..1371361)	Azoarcus sp. BH72	4606781
YP_932778.1	CDS	azo1274	NC_008702.1	1371358	1372500	R	TREMBL:Q88RI7 (56% identity); TREMBL:Q8PGP6 (42% identity). Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting six transmembrane helices.; Specificity unclear; putative ABC transporter permease	complement(1371358..1372500)	Azoarcus sp. BH72	4606782
YP_932779.1	CDS	yjjK	NC_008702.1	1372520	1374184	R	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein	complement(1372520..1374184)	Azoarcus sp. BH72	4606783
YP_932780.1	CDS	azo1276	NC_008702.1	1374585	1375484	D	Putative methyltransferase Rv0089/MT0098/Mb0092 (EC 2.1.1.-). Methyl transfer from the ubiquitous S-adenosyl-L-methionine (AdoMet) to either nitrogen, oxygen or carbon atoms is frequently employed in diverse organisms TREMBL:AAS95087-36%identity,50% similarity InterPro: SAM (and some other nucleotide) binding motif rrmJ: ribosomal RNA large subunit methylation TIGRFAM:Transcription regulator, AsR family, Ubi/COQ family.; Family membership; putative O-methyltransferase	1374585..1375484	Azoarcus sp. BH72	4610190
YP_932781.1	CDS	azo1277	NC_008702.1	1375505	1375996	R	conserved hypothetical glutathione peroxidase. Homolgy to pp1874 pf P. putida of 66% (trembl|Q88LQ5) Glutathione peroxidase (GSHPx), an enzyme whose principal function is to protect against damage from endogenously-formed hydroxyperoxides, catalyses the reduction of hydroxyperoxides by glutathione Pfam: Glutatione peroxidase no signal peptide no TMHs; Family membership; glutathione peroxidase	complement(1375505..1375996)	Azoarcus sp. BH72	4606784
YP_932782.1	CDS	azo1278	NC_008702.1	1376095	1378737	R	EAL/GGDEF/PAS/PAC-domain containing signalling protein,; Conserved hypothetical protein; EAL/GGDEF/PAS/PAC-domain-containing signalling protein	complement(1376095..1378737)	Azoarcus sp. BH72	4606785
YP_932783.1	CDS	azo1279	NC_008702.1	1378734	1379822	R	Probable cytochrome c peroxidase (EC 1.11.1.5), an electron-transfer proteins having one or several haem c groups, bound to the protein by one or, more generally,two thioether bonds involving sulphydryl groups of cysteine residues. CytC possess a wide range of properties and function in a large number of different redox processes. Similar to yhjA from E.coli.; High confidence in function and specificity; putative cytochrome C peroxidase	complement(1378734..1379822)	Azoarcus sp. BH72	4606786
YP_932784.1	CDS	fpr1	NC_008702.1	1379865	1380641	R	Ferredoxin-NADP+ reductase (EC 1.18.1.2) Homology to fpr of A. vinelandii of 79% (sprot|FENR_AZOVI). CATALYTIC ACTIVITY: Reduced ferredoxin + NADP(+) = oxidized ferredoxin + NADPH. Pfam: Oxidoreductase FAD-binding doamin; Oxidoreductase NAD-binding domain no signal peptide no TMHs; High confidence in function and specificity; ferredoxin-NADP+ reductase	complement(1379865..1380641)	Azoarcus sp. BH72	4606787
YP_932785.1	CDS	azo1281	NC_008702.1	1380741	1381667	D	Probable transcriptional regulator, LysR family proteins.57% Identity to TrEMBL;Q9HYK6, Q87XZ5, Q88MD6. Has PF03466, LysR substrate binding domain;IPR005119,LysR_subst; The structure of this domain is known and is IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family,groups together a range of proteins, including ampR, catM,catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR,mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR,syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini.; High confidence in function and specificity; LysR family transcriptional regulator	1380741..1381667	Azoarcus sp. BH72	4608824
YP_932786.1	CDS	ndvB	NC_008702.1	1381825	1384443	R	Beta-(1-3)-glucosyl transferase, involved in the synthesis of the cyclic beta-(1,3),(1,6)-D-glucan. 36% Glyco_trans_2. Pfam:PF00535; Glycos_transf_2. Signal peptide: present. TMhelix:9.; Function unclear; putative Beta-(1-3)-glucosyl transferase	complement(1381825..1384443)	Azoarcus sp. BH72	4606788
YP_932787.1	CDS	azo1283	NC_008702.1	1384729	1385121	D	Conserved hypothetical membrane protein. Homology to PP1739 of P. putida of 30% (trembl|Q8EA80) No domains predicted. signal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	1384729..1385121	Azoarcus sp. BH72	4609351
YP_932788.1	CDS	ndvC	NC_008702.1	1385065	1386660	R	Glucan 1-3-beta-glucosidase precursor.(Exo-13-beta-glucanase).Glucanases possibly play a role in cell expansion during growth in cell-cell fusion during mating and in spore release during sporulation. This enzyme may be involved in beta- glucan degradation and also function biosynthetically as a transglycosylase. 47%; Function unclear; putative glucan 1,3-beta-glucosidase	complement(1385065..1386660)	Azoarcus sp. BH72	4606789
YP_932789.1	CDS	gcvP	NC_008702.1	1386740	1389619	R	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase	complement(1386740..1389619)	Azoarcus sp. BH72	4609352
YP_932790.1	CDS	gcvH	NC_008702.1	1389681	1390064	R	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H	complement(1389681..1390064)	Azoarcus sp. BH72	4608871
YP_932791.2	CDS	gcvT	NC_008702.1	1390115	1391206	R	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T	complement(1390115..1391206)	Azoarcus sp. BH72	4608870
YP_932792.1	CDS	narK	NC_008702.1	1397768	1398982	D	Probable nitrate transporters are involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. NarK is polytopic membrane protein with 12 transmembrane domains which is involved in nitrate uptake and nitrite excretion and is thought to function as a nitrate/nitrite antiporter. At low concentrations of nitrate, NarK mediates the electrogenic excretion of nitrite rather than nitrate/nitrite exchange., 90% similarity to a probable nitrate transporter protein in Azoarcus sp. EbN1., InterPRo:04737: nitrate transporterSignal peptide no present, TMHx:12 ,; High confidence in function and specificity; putative nitrate transporter	1397768..1398982	Azoarcus sp. BH72	4608235
YP_932793.1	CDS	azo1289	NC_008702.1	1399088	1400770	D	Putative serine/threonine protein kinase,; Family membership; putative serine/threonine protein kinase	1399088..1400770	Azoarcus sp. BH72	4609340
YP_932794.1	CDS	azo1290	NC_008702.1	1400786	1401718	R	Conserved hypothetical protein. Homology to ebA98 of Azoarcus sp. EbN1 of 67% (gnl|keqq|eba:ebA983(KEGG)). No domains predicted. No signal peptide. No TMHs; hypothetical protein	complement(1400786..1401718)	Azoarcus sp. BH72	4606790
YP_932795.1	CDS	sixA	NC_008702.1	1401860	1402312	R	Putative phosphohistidine phosphatase, SixA. TIGRFAM: TIGR00249; sixA. Phosphohistidine phosphatase sixA (EC 3.1.3.-) (RX6). EXHIBITS PHOSPHOHISTIDINE PHOSPHATASE ACTIVITY TOWARDS THE HPT DOMAIN OF THE ARCB SENSOR INVOLVED IN THE MULTISTEP HIS- ASP PHOSPHORELAY.; Specificity unclear; putative phosphohistidine phosphatase	complement(1401860..1402312)	Azoarcus sp. BH72	4606791
YP_932796.1	CDS	azo1292	NC_008702.1	1402375	1403868	R	Conserved hypothetical protein,40% identity to TrEMBL;Q88AR4 Has PF01928|CYTH domain(IPR008172);These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3',5'-cyclic AMP and pyrophosphate. Has PF05235:CHAD domain(IPR007899);The CHAD domain is an alpha-helical domain functionally associated with the CYTH domains. It has conserved histidines that may chelate metals.; adenylate cyclase	complement(1402375..1403868)	Azoarcus sp. BH72	4609871
YP_932797.1	CDS	glnE	NC_008702.1	1403946	1406627	R	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase	complement(1403946..1406627)	Azoarcus sp. BH72	4606792
YP_932798.1	CDS	azo1294	NC_008702.1	1406776	1410699	D	Conserved hypothetical protein. Homology to cv2096 of C. violaceum of 32% (trembl|Q7NW94(SRS) no domains predicted no signal peptide 1 TMHs; hypothetical protein	1406776..1410699	Azoarcus sp. BH72	4608897
YP_932799.1	CDS	azo1295	NC_008702.1	1410696	1411553	D	conserved hypothetical carbon-nitrogen hydrolase. Homolog to bb1933 of B. bronchiseptica (trembl|Q7WL17). InterPro: Carbon-nitrogen hydrolase (IPR003010) Pfam: Carbon-nitorgen hydrolase no signal peptide no TMHs; Conserved hypothetical protein; carbon-nitrogen hydrolase	1410696..1411553	Azoarcus sp. BH72	4606793
YP_932800.1	CDS	tldD	NC_008702.1	1411624	1413069	D	Probable TldD protein. Homology to tldD of E. coli of 59% (sprot|TLDD_ECOLI). Suppresses the inhibitory activity of the carbon storage regulator (csrA). Pfam: putative modulator of DNA gyrase no signal peptide no TMHs; Function unclear; TldD protein	1411624..1413069	Azoarcus sp. BH72	4606794
YP_932801.1	CDS	azo1297	NC_008702.1	1413077	1413520	R	Conserved hypothetical protein. Homology to CV3985 of C.violaceum of 42% (tremble:Q7NR00). Has PF07025:(IPR010745)Protein of unknown function (DUF1316);This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. No signal peptide or TMH present.; hypothetical protein	complement(1413077..1413520)	Azoarcus sp. BH72	4609951
YP_932802.1	CDS	azo1298	NC_008702.1	1413533	1414231	R	Conserved hypothetical membrane protein. Homology to cv3984 of C. violaceum of 47% (trembl|Q7NR01(SRS)) no domains predicted no signal peptide 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(1413533..1414231)	Azoarcus sp. BH72	4606795
YP_932803.1	CDS	azo1299	NC_008702.1	1414245	1415591	R	Hypothetical protein,50% identity (67% similarity)to TrEMBL;Q7NR02. TrEMBL;Q88IA6(39%),Q8XRU1(37%). Has PF05936(IPR010263):Bacterial protein of unknown function (DUF876);This family consists of a series of hypothetical bacterial sequences of unknown function. No Signal Peptide or TMH reported present.; Function unclear; hypothetical protein	complement(1414245..1415591)	Azoarcus sp. BH72	4606796
YP_932804.1	CDS	azo1300	NC_008702.1	1415603	1416217	R	Hypothetical protein,34% identity (52% similarity) to TrEMBL;Q7NR03. No domains, repeats, motifs or features were predicted with confidence.; Function unclear; hypothetical protein	complement(1415603..1416217)	Azoarcus sp. BH72	4606797
YP_932805.1	CDS	azo1301	NC_008702.1	1416388	1417059	D	Hypothetical membrane protein. No homology of the entire protein with the data bank. Pfam: D-alanyl-D-alanine carboxypeptidase (101-209 aa) no signal peptide 1 TMHs; hypothetical protein	1416388..1417059	Azoarcus sp. BH72	4606798
YP_932806.1	CDS	azo1302	NC_008702.1	1417056	1420748	D	Conserved hypothetical membrane protein. Homology to CV3712 of Chromobacterium violaceum of 35% (trembl|Q7NR05) Signal P reporting Signal Peptide Present. TMHMM2 reporting 2 TMH's present. Has PF06761:(IPR009612)ImcF-related;This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed [1] to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical proteins. Has PF06744,(IPR010623)Protein of unknown function (DUF1215);This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency.; Conserved hypothetical protein; hypothetical protein	1417056..1420748	Azoarcus sp. BH72	4606799
YP_932807.1	CDS	azo1303	NC_008702.1	1420836	1421360	D	Hypothetical protein,50% identity (66% Similarity) to TrEMBL;Q8XRT8. TrEMBL;Q7NR06(60% identity,74% similarity). Has PF05591;Protein of unknown function (DUF770)(IPR008312)This family consists of several proteins of unknown function from various bacterial species. No Signal peptide or TMH present.; Function unclear; hypothetical protein	1420836..1421360	Azoarcus sp. BH72	4606800
YP_932808.1	CDS	azo1304	NC_008702.1	1421344	1422837	D	Hypothetical protein,63% identity (81% similarity) to TrEMBL;Q8XRT7. TrEMBL;Q7NR07(73% identity,86% similarity). Has (IPR010269 )PF05943:Protein of unknown function (DUF877);This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown. No Signal peptide or TMH present.; Function unclear; hypothetical protein	1421344..1422837	Azoarcus sp. BH72	4606801
YP_932809.1	CDS	azo1305	NC_008702.1	1422881	1423378	D	Conserved hypothetical protein. Homology to CV3977 of C.violaceum of 77% (tremble:Q7NR08). Has PF05638:(IPR008514)Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. No signal peptide or TMH present.; hypothetical protein	1422881..1423378	Azoarcus sp. BH72	4606802
YP_932810.1	CDS	azo1306	NC_008702.1	1423378	1423854	D	Hypothetical secreted protein. Homology to CV3976 of Chromobacterium violaceum of 26% (trembl|Q7NR09(SRS)). No TMHs Signal Peptide Present. Has PF00691:OmpA family;(IPR006665 OmpA/MotB):The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.; hypothetical protein	1423378..1423854	Azoarcus sp. BH72	4606803
YP_932811.1	CDS	azo1307	NC_008702.1	1423911	1426628	D	Probable vgr-related protein,41% identity (55% similarity) to TrEMBL;Q7NY43. TrEMBL;Q8XSF8 Has (IPR006533 Rhs_Vgr)PF04524:Protein of unknown function, DUF586;This family contains a conserved region in several bacterial proteins of unknown function. Coils2 program predicts presence of a coiled coil.; Vgr related protein	1423911..1426628	Azoarcus sp. BH72	4606804
YP_932812.1	CDS	azo1308	NC_008702.1	1426635	1428473	D	Conserved hypothetical protein. Homology to CV3969 of C.violaceum of 56% (tremble: Q7NR16). Has (IPR010272)PF05947:Bacterial protein of unknown function (DUF879);This family consists of several hypothetical bacterial proteins of unknown function. No signal peptide or TMH present.; hypothetical protein	1426635..1428473	Azoarcus sp. BH72	4606805
YP_932813.1	CDS	azo1309	NC_008702.1	1428437	1429453	D	Conserved hypothetical protein. Homology to CV3967 of C.violaceum of 45% (tremble:Q7NR18) Has (IPR010732)PF06996:Protein of unknown function (DUF1305);This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence. No signal peptide or TMH reported present.; hypothetical protein	1428437..1429453	Azoarcus sp. BH72	4606806
YP_932814.1	CDS	azo1310	NC_008702.1	1429450	1430565	R	Conserved hypothetical protein. Homology to CV3963 of C.violaceum of 37% (tremble:Q7NR22). Has (IPR01065)PF06812:ImpA-related N-terminal;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins. No signal peptide present. No TMH present.; hypothetical protein	complement(1429450..1430565)	Azoarcus sp. BH72	4606807
YP_932815.1	CDS	azo1311	NC_008702.1	1430572	1430835	R	conserved hypothetical protein Has 2 PF05488 PAAR motif(IPR008727);This motif is found usually in pairs in a family of bacterial membrane proteins. It is also found as a triplet of tandem repeats comprising the entire length in a another family of hypothetical proteins.; Function unclear; hypothetical protein	complement(1430572..1430835)	Azoarcus sp. BH72	4606808
YP_932816.1	CDS	azo1312	NC_008702.1	1431039	1432133	D	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase	1431039..1432133	Azoarcus sp. BH72	4606809
YP_932817.1	CDS	phnA	NC_008702.1	1432168	1432506	D	PhnA protein: Phosphonoacetate hydrolase is a novel carbon-phosphorus bond cleavage enzyme.The phnA gene is part of a large operon in Escherichia coli associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. PhnA is found in both gram positive 69% PhnA.PhnA protein Pfam:PF03831; PhnA; 1. TIGRFAMs:TIGR00686; phnA; 1.; High confidence in function and specificity; putative phosphonoacetate hydrolase	1432168..1432506	Azoarcus sp. BH72	4606810
YP_932818.1	CDS	azo1314	NC_008702.1	1432522	1432893	R	Conserved hypothetical protein. Homology to ebA3072 Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA3072(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1432522..1432893)	Azoarcus sp. BH72	4609549
YP_932819.1	CDS	azo1315	NC_008702.1	1432952	1433749	R	Conserved hypothetical membrane protein. Homology to blr8071 of B. japonicum of 56% (trembl|Q89BS7). No domains predicted signal peptide probable 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1432952..1433749)	Azoarcus sp. BH72	4606811
YP_932820.1	CDS	azo1316	NC_008702.1	1433746	1434351	R	47% AAA_ATPase.IPR003439; ABC_transporter.IPR008995. Pfam:PF00005; ABC_tran; 1. SMART:SM00382; AAA; 1. non-secretory protein; Function unclear; putative ATP binding protein	complement(1433746..1434351)	Azoarcus sp. BH72	4606812
YP_932821.1	CDS	azo1317	NC_008702.1	1434635	1435387	D	Conserved hypothetical protein. Homology to CCO1214 of Campylobacter coli of 38% (gi|57168023|ref|ZP_00367162.1|(NBCI ENTREZ)). Has PF07021, Methionine biosynthesis protein MetW;IPR010743; This family consists of several bacterial and one archaeal methionine biosynthesis MetW proteins. Biosynthesis of methionine from homoserine in Pseudomonas putida takes place in three steps. The first step is the acylation of homoserine to yield an acyl-L-homoserine. This reaction is catalysed by the products of the metXW genes and is equivalent to the first step in enterobacteria, gram-positive bacteria and fungi, except that in these microorganisms the reaction is catalysed by a single polypeptide (the product of the metA gene in Escherichia coli and the met5 gene product in Neurospora crassa). In Pseudomonas putida, as in gram-positive bacteria and certain fungi, the second and third steps are a direct sulfhydrylation that converts the O-acyl-L-homoserine into homocysteine and further methylation to yield methionine. The latter reaction can be mediated by either of the two methionine synthetases present in the cells. No signal peptide. No TMHs.; hypothetical protein	1434635..1435387	Azoarcus sp. BH72	4606813
YP_932822.1	CDS	azo1318	NC_008702.1	1435529	1436443	R	Conserved hypothetical membrane protein. Homology to RS04440 of Ralstonia solanacearum of 40% (trembl|Q8Y277) TMHMM2 reporting 2 TMH's present. Signal peptide Present. Has PF04280;Tim44-like domain(IPR007379):Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region. This family includes the C-terminal region of Tim44 that has been shown to form a stable proteolytic fragment in yeast. This region is also found in a set of smaller bacterial proteins. The molecular function of the bacterial members of this family is unknown but transport seems likely.; Conserved hypothetical protein; hypothetical protein	complement(1435529..1436443)	Azoarcus sp. BH72	4606814
YP_932823.1	CDS	azo1319	NC_008702.1	1436614	1437468	R	Hypothetical protein Rv1403c/MT1447/Mb1438c precursor. TREMBL:Q92U99_Putative methyl transferase, S-adenosyl-L-methionine (SAM)-29% identity, 42% similarity. InterPro: ubiE/COQ5 methyltransferase pimt: protein-L-isoaspartate O-methyltr Pfam: ubiE/COQ5 methyl transferase family, Dihydrodipicolinate synthetase family, TerD (Bacterial stress protein domains). HTH_1 predicted regulatory helix turn helix. TIGRFAM: moaC, met p-daseII; Specificity unclear; putative methyltransferase	complement(1436614..1437468)	Azoarcus sp. BH72	4606815
YP_932824.1	CDS	azo1320	NC_008702.1	1437635	1438639	D	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	1437635..1438639	Azoarcus sp. BH72	4606816
YP_932825.1	CDS	azo1321	NC_008702.1	1438850	1439548	D	Conserved hypothetical protein. Homology to Psyc03001842 of Psychrobacter sp. 273-4 of 57% (gi|52853589|ref|ZP_00145853.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1438850..1439548	Azoarcus sp. BH72	4606817
YP_932826.1	CDS	azo1322	NC_008702.1	1439761	1440165	D	hypothetical protein	1439761..1440165	Azoarcus sp. BH72	4606818
YP_932827.1	CDS	azo1323	NC_008702.1	1440382	1441617	D	Probable protein kinase InterPro: Protein kinase,Protein kinase-like; protein kinase	1440382..1441617	Azoarcus sp. BH72	4606819
YP_932828.1	CDS	azo1324	NC_008702.1	1441791	1442165	R	C-terminal part of GTP-binding protein hflX. TREMBL:Q7NU63: 66% identity; 83% similarity ( the protein of query matches only with C-terminal part (124 aminoacids) of putative GTP binding proteins in the database) InterPro:IPR006073; GTP1_OBG. PRINTS:PR00326; GTP1OBG Pfam:Sigma54_activat: Sigma-54 interaction domain Absence of transmembrane helices (TMHMM predicted); Function unclear; GTP binding protein	complement(1441791..1442165)	Azoarcus sp. BH72	4606820
YP_932829.1	CDS	azo1325	NC_008702.1	1442281	1443378	R	Region start changed from 1443402 to 1443378 (-24 bases), , Changed start codon from att to next atg; hypothetical protein	complement(1442281..1443378)	Azoarcus sp. BH72	4606821
YP_932830.1	CDS	azo1326	NC_008702.1	1443478	1443669	D	Hypothetical Protein. No domains, repeats, motifs or features could be predicted above threshold scores.; hypothetical protein	1443478..1443669	Azoarcus sp. BH72	4606822
YP_932831.1	CDS	hflX2	NC_008702.1	1443843	1445237	R	GTP-binding protein hflX. trembl:Q7NU63:77% identity, 83% similarity The proteins contain GTP-binding motifs and are GTP1_OBG. PRINTS:PR00326; GTP1OBG Pfam:MMR_HSR1:GTPase of unknown function thdF: tRNA modification GTPase TrmE No signal peptide present (SignalP predicted). No transmembrane helices present (TMHMM predicted); Family membership; GTP-binding protein HflX	complement(1443843..1445237)	Azoarcus sp. BH72	4606823
YP_932832.1	CDS	azo1328	NC_008702.1	1445591	1446979	D	Conserved hypothetical protein. Fusion Protein of bacterial extracellular solute-binding protein and transglycosylase Homology to pp1036 of P. putida of 37% (trembl|Q88P17) InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein/glutamate receptor (IPR001311); SLT domain (IPR000189) Pfam: Bacterial extracellular solute-binding protein; Transglycosylase SLT domain signal peptide no TMHs recN: DNA repair protein RecN; hypothetical protein	1445591..1446979	Azoarcus sp. BH72	4610017
YP_932833.1	CDS	aapM	NC_008702.1	1446976	1448064	R	Putative amino-acid ABC transporter permease. Homology to aapM of R. leguminosarum of 38% (sprot|AAPM_RHILV) PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YDHWXYZ FOR AN AMINO ACID; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. Pfam: binding-protein-dependent transport system signal peptide probable 8 TMHs; Family membership; putative amino acid permease	complement(1446976..1448064)	Azoarcus sp. BH72	4606824
YP_932834.1	CDS	aapQ	NC_008702.1	1448061	1449080	R	Putative amino acid permease. Homology to aapQ of R. leguminosarum of 35% (sprot|AAPQ_RHILVast). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS. AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein -dependent transport system 1 HTH no signal peptide probable 4 TMHs; Family membership; putative amino acid permease	complement(1448061..1449080)	Azoarcus sp. BH72	4608241
YP_932835.1	CDS	aapJ	NC_008702.1	1449038	1450072	R	Putative amino acid ABC transporter periplasmic binding protein. Homology to aapJ of R. leguminosarum of 52% (sprot|AAPJ_RHILV). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein/glutamate receptor (IPR001311) Pfam: Bacterial extracellular solute-binding proteins signal peptide no TMHs TIGR00045: conserved hypothetical prote; High confidence in function and specificity; putative amino acid-binding protein	complement(1449038..1450072)	Azoarcus sp. BH72	4608242
YP_932836.1	CDS	cbl	NC_008702.1	1450197	1451132	R	HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 55% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity; transcriptional regulator CysB-like protein	complement(1450197..1451132)	Azoarcus sp. BH72	4608240
YP_932837.1	CDS	cysA	NC_008702.1	1451135	1452220	R	Sulfate/thiosulfate import ATP-binding protein cysA (EC 3.6.3.25) (Sulfate-transporting ATPase). Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system (By similarity). InterPro: AAA ATPase superfamily ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity; putative sulfate transport ATP-binding protein	complement(1451135..1452220)	Azoarcus sp. BH72	4608436
YP_932838.1	CDS	cysW	NC_008702.1	1452232	1453119	R	Sulfate transport system permease cysW. Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component uppS: undecaprenyl diphosphate synthase; High confidence in function and specificity; putative sulfate transport system permease	complement(1452232..1453119)	Azoarcus sp. BH72	4608554
YP_932839.1	CDS	cysT	NC_008702.1	1453119	1453973	R	Probable sulfate transport system permease cysT. Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). InterPro: Binding-protein-dependent transport systems inner membrane component gntP: gluconate transporter; High confidence in function and specificity; sulfate transporter permease	complement(1453119..1453973)	Azoarcus sp. BH72	4608566
YP_932840.1	CDS	cysP	NC_008702.1	1453973	1454983	R	CysP: sulfate/thiosulfate periplasmic binding protein. Sulfate-binding protein precursor (Sulfate starvation-induced protein 2) (SSI2). This protein specifically binds sulfate and is involved in its transmembrane transport. mazG: MazG family protein; High confidence in function and specificity; putative sulfate transport system substrate-binding protein	complement(1453973..1454983)	Azoarcus sp. BH72	4608565
YP_932841.1	CDS	azo1337	NC_008702.1	1455298	1456512	D	Conserved hypothetical peptidoglycan binding protein. Homology to bb3579 of b. bronchiseptica of 69% (trembl|Q7WGL0) InterPro: Putative peptidoglycan binding domain 1 (IPR002477) Pfam: Putative peptidoglycan binding domain This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. signal peptide no TMHs; Family membership; peptidoglycan-binding protein	1455298..1456512	Azoarcus sp. BH72	4608563
YP_932842.1	CDS	azo1338	NC_008702.1	1456606	1457373	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8FWK3 (58% identity); TREMBL:Q9AHY1 (58% identity). Pfam (PF00106): Short chain dehydrogenase.; Family membership; short-chain dehydrogenase	1456606..1457373	Azoarcus sp. BH72	4606825
YP_932843.1	CDS	ccoI	NC_008702.1	1457532	1460015	D	36% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg. IPR006121; HeavyMe_transpt.IPR000695; H_ATPase.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TMHs:8; Specificity unclear; putative cation-transporting ATPase	1457532..1460015	Azoarcus sp. BH72	4606826
YP_932844.1	CDS	ccoS	NC_008702.1	1460020	1460229	D	Conserved hypothetical cytochrome oxidase maturation protein. Homology to cco of P.Putida of 42% (gnl|keqq|ppu:PP4262(KEGG)). Pfam: Cytochrome oxidase maturation protein cbb3-type. Genes encoding a cytochrome cbb3 oxidase were initially designated fixNOQP (ccoNOQP),the ccoNOQP operon is always found close to a second gene cluster, known as fixGHIS (ccoGHIS) whose expression is necessary for the assembly of a functional cbb3 oxidase. On the basis of their derived amino acid sequences each of the four proteins encoded by the ccoGHIS operon are thought to be membrane-bound. It has been suggested that they may function in concert as a multi-subunit complex,possibly playing a role in the uptake and metabolism of copper required for the assembly of the binuclear centre of cytochrome cbb3 oxidase. Interpro: IPR004714 Cytochrome oxidase maturation protein cbb3-type. No signal peptide. 1 TMHs; Conserved hypothetical protein; cytochrome oxidase maturation protein	1460020..1460229	Azoarcus sp. BH72	4608453
YP_932845.1	CDS	ccoN	NC_008702.1	1460596	1462020	D	CcoN; FixN; cbb3-type cytochrome c oxidase subunit I	1460596..1462020	Azoarcus sp. BH72	4608458
YP_932846.1	CDS	ccoO	NC_008702.1	1462036	1462671	D	CcoO; FixO; cbb3-type cytochrome c oxidase subunit II	1462036..1462671	Azoarcus sp. BH72	4608454
YP_932847.1	CDS	ccoQ	NC_008702.1	1462691	1462864	D	Cbb3-type cytochrome oxidase, subunit ccoQ , 44% Identity to TrEMBL;Q8D9I3, Q7MKV5,Q9KS21. Has PF05545,Cbb3-type cytochrome oxidase component FixQ; IPR008621;This family consists of several Cbb3-type cytochrome oxidase components (FixQ/CcoQ). FixQ is found in nitrogen fixing bacteria. Since nitrogen fixation is an energy-consuming process, effective symbioses depend on operation of a respiratory chain with a high affinity for O2, closely coupled to ATP production. This requirement is fulfilled by a special three-subunit terminal oxidase (cytochrome terminal oxidase cbb3), which was first identified in Bradyrhizobium japonicum as the product of the fixNOQP operon.; Cbb3-type cytochrome oxidase subunit	1462691..1462864	Azoarcus sp. BH72	4608455
YP_932848.1	CDS	ccoP	NC_008702.1	1462868	1463761	D	Probable cytochrome C oxidase subunit III. Homology to ccoP of P. stutzeri of 46% (trembl|Q8KS19) CYTOCHROME C OXIDASE IS THE COMPONENT OF THE RESPIRATORY CHAIN THAT CATALYZES THE REDUCTION OF OXYGEN TO WATER. SUBUNITS 1- 3 FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. CO I IS THE CATALYTIC SUBUNIT OF THE ENZYME. ELECTRONS ORIGINATING IN CYTOCHROME C OR A QUINOL ARE TRANSFERRED TO THE BIMETALLIC CENTER FORMED BY A HIGH-SPIN HEME AND COPPER B. Tigrfam: ccoP: cytochrome c oxidase cbb3-type Pfam: cytochrome c no signal peptide probable 2 TMHs; High confidence in function and specificity; cytochrome c oxidase, cbb3-type subunit III	1462868..1463761	Azoarcus sp. BH72	4608457
YP_932849.1	CDS	ccoG	NC_008702.1	1463836	1465260	D	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to fixG of R. meliloti of 36% (FIXG_RHIME). Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; they fall into several subgroups according to the nature of their iron-sulphur cluster(s). One group,originally found in bacteria, has been termed ''bacterial-type'', in which the active centre is a 4Fe-4S cluster. 4Fe-4S ferredoxins may in turn be subdivided into further groups, based on their sequence properties. Most contain at least one conserved domain, including four Cys residues that bind to a 4Fe-4S centre. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) probable 5 TMHs . No signal peptide predicted.; Family membership; putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein	1463836..1465260	Azoarcus sp. BH72	4608456
YP_932850.1	CDS	ccoH	NC_008702.1	1465265	1465780	D	Conserved hypothetical membrane protein. Homology to ebA5136 Azoarcus sp. EbN1 of 51% (gnl|keqq|eba:ebA5136(KEGG)). Has PF05751, FixH;IPR008620; This family consists of several Rhizobium FixH like proteins. It has been suggested that suggested that the four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalysed by FixG. No signal peptide predicted. 1 TMHs; Conserved hypothetical protein; hypothetical protein	1465265..1465780	Azoarcus sp. BH72	4608451
YP_932851.1	CDS	azo1347	NC_008702.1	1465806	1465955	D	Hypothetical membrane protein. No homology to the data bank. No domain predicted. No signal peptide 1 TMH; hypothetical protein	1465806..1465955	Azoarcus sp. BH72	4608452
YP_932852.1	CDS	azo1348	NC_008702.1	1465986	1466222	D	Probable transmemebrane Protein, 38% Idneity to TrEMBL;Q8XZW3 Signal P reporting Signal peptide present. TMHMM2 reporting 1 TMH present.; transmembrane protein	1465986..1466222	Azoarcus sp. BH72	4606827
YP_932853.1	CDS	azo1349	NC_008702.1	1466484	1466927	R	Putative universal stress protein F,; Conserved hypothetical protein; putative universal stress protein f	complement(1466484..1466927)	Azoarcus sp. BH72	4609982
YP_932854.1	CDS	phbC2	NC_008702.1	1467151	1468884	D	FUNCTION: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name :-PHBC_AZOCA Primary accession number:- O66392 Identity:-41% InterPro :- IPR000073; A/b_hydrolase. Pfam:- PF07167; PhaC_N; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; poly-beta-hydroxybutyrate synthase	1467151..1468884	Azoarcus sp. BH72	4606829
YP_932855.1	CDS	fnr	NC_008702.1	1468907	1469707	R	Fumarate and nitrate reduction regulatory protein. Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor O(2) is no longer available it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration. Similar to SWISSPROT: sprot|FNR_ECOLI (39% Escherichia coli, fumarate and nitrate reduction regulatory protein Fnr) / sprot|ANR_PSEAE (40% Pseudomonas aeruginosa,transcriptional activator protein Anr) InterPro: IPR000595 cNMP_binding. IPR001808 HTH_Crp. Pfam: PF00027 cNMP_binding. PF00325 Crp. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; fumarate and nitrate reduction regulatory protein	complement(1468907..1469707)	Azoarcus sp. BH72	4609542
YP_932856.1	CDS	hemN	NC_008702.1	1469756	1471147	D	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase	1469756..1471147	Azoarcus sp. BH72	4608816
YP_932857.1	CDS	azo1353	NC_008702.1	1471235	1471951	D	Conserved hypothetical membrane protein. Homology to ebA5153 of Azoarcus sp. EbN1 of 79% (gnl|keqq|eba:ebA5153(KEGG)). Has PF02683;Cytochrome C biogenesis protein transmembrane region (IPR003834 Ctytoch_TM): This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family. No signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	1471235..1471951	Azoarcus sp. BH72	4608988
YP_932858.1	CDS	copY	NC_008702.1	1471968	1472363	R	Heavy metal dependent transcription regulator 2. TRANSCRIPTIONAL REGULATOR INVOLVED IN ACID TOLERANCE. BINDS COPPER (By similarity). It contains a n-terminal dna binding region and a c- terminal metal binding region (by similarity). 35% HTH_MerR.IPR009061; Putativ_DNA_bind. Pfam:PF00376; MerR; 1. TIGR00372: conserved hypothetical protei; High confidence in function and specificity; putative regulatory protein	complement(1471968..1472363)	Azoarcus sp. BH72	4606830
YP_932859.1	CDS	copA	NC_008702.1	1472442	1474877	D	CopA: copper transporting P-type ATPase,involved in the uptake and metabolism of copper. 44% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR001756; Cu_ATPase.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg.IPR006121; HeavyMe_transpt.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TIGR00003: copper-ion-binding protein. TMHs:8.; High confidence in function and specificity; putative Cu2+ transporting ATPase	1472442..1474877	Azoarcus sp. BH72	4608516
YP_932860.1	CDS	copZ	NC_008702.1	1474902	1475111	D	Conserved hypothetical copper chaperon. Homology to copZ of copZ Azoarcus sp. EbN1 of 66%. Pfam: Heavy-metal-associated domain. Proteins that transport heavy metals in micro-organisms and mammals share similarities in their sequences and structures. Tigrfam: TIGR00003: copper-ion-binding protein. No signal peptide. No TMHs.; Conserved hypothetical protein; copper chaperon	1474902..1475111	Azoarcus sp. BH72	4608513
YP_932861.1	CDS	azo1357	NC_008702.1	1475126	1477969	R	EAL/GGDEF/PAS/PAC-domain containing signalling protein,; Conserved hypothetical protein; EAL/GGDEF/PAS/PAC-domain-containing signalling protein	complement(1475126..1477969)	Azoarcus sp. BH72	4608517
YP_932862.1	CDS	ppa	NC_008702.1	1478241	1478768	D	Probable inorganic pyrophosphatase. Homology to ppa of E. coli of 66% (sprot|IPYR_ECOLI). CATALYTIC ACTIVITY Diphosphate + H(2)O = 2 phosphate. Pfam: Inorganic pyrophospatease no signal peptide no TMHs; High confidence in function and specificity; inorganic pyrophosphatase	1478241..1478768	Azoarcus sp. BH72	4606831
YP_932863.1	CDS	azo1359	NC_008702.1	1478841	1479977	R	Conserved hypothetical protein. Homology to BB3581 of B.bronchiseptica of 53% (tremble:Q7WGK8). Has PF04339:(IPR00743)Protein of unknown function, DUF482;This family contains several proteins of uncharacterised function. NO signal peptide or TMH present.; hypothetical protein	complement(1478841..1479977)	Azoarcus sp. BH72	4609607
YP_932864.1	CDS	nadE	NC_008702.1	1480139	1481755	D	NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase	1480139..1481755	Azoarcus sp. BH72	4606832
YP_932865.1	CDS	glnB	NC_008702.1	1481805	1482143	D	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ2 (100%) and to trembl|Q8XWX5 (82%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity; PII-like signal transmitter protein GlnB	1481805..1482143	Azoarcus sp. BH72	4609306
YP_932866.1	CDS	azo1362	NC_008702.1	1482173	1483225	R	Hypothetical protein. no homology of the entire protein with the data bank. Pfam: Smr domain InterPro: Smr domain This family includes the Smr (Small MutS Related) proteins, and the C-terminal region of the MutS2 protein. It has been suggested that this domain interacts with the MutS1 protein in the case of Smr proteins and with the N-terminal MutS related region of MutS2. no signal peptide no TMHs; hypothetical protein	complement(1482173..1483225)	Azoarcus sp. BH72	4608895
YP_932867.1	CDS	trxB2	NC_008702.1	1483241	1484191	R	Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity; thioredoxin-disulfide reductase	complement(1483241..1484191)	Azoarcus sp. BH72	4606833
YP_932868.1	CDS	vfr	NC_008702.1	1484423	1485094	D	Probable cyclic amp receptor-like protein,; High confidence in function and specificity; cyclic AMP receptor protein	1484423..1485094	Azoarcus sp. BH72	4610042
YP_932869.1	CDS	FtsK	NC_008702.1	1485243	1487531	D	DNA translocase ftsK 2. InterPro: FtsK/SpoIIIE family; High confidence in function and specificity; putative cell division protein	1485243..1487531	Azoarcus sp. BH72	4610092
YP_932870.1	CDS	lolA	NC_008702.1	1487528	1488205	D	Putative outer-membrane lipoprotein carrier protein. Homology to lolA of E. coli of 25% (sprot|LOLA_ECOLI) Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity). Pfam: outer membrane lipoprotein carrier protein LolA Tigrfam: lolA: outer membrane lipoprotein carrier singal peptide no TMHs; Family membership; putative outer membrane lipoprotein carrier protein	1487528..1488205	Azoarcus sp. BH72	4608837
YP_932871.1	CDS	azo1367	NC_008702.1	1488217	1489554	D	Hypothetical protein CBU1189. InterPro: AAA-protein (ATPases associated with various cellular activities) ruvB: Holliday junction DNA helicase R.; Specificity unclear; recombination factor protein RarA	1488217..1489554	Azoarcus sp. BH72	4609168
YP_932872.1	CDS	azo1368	NC_008702.1	1489593	1489856	R	Conserved hypothetical protein. Homology to ebA7035 of Azoarcus sp. EbN1 of 79% (gnl|keqq|eba:ebA7035(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1489593..1489856)	Azoarcus sp. BH72	4606834
YP_932873.1	CDS	azo1369	NC_008702.1	1490125	1491417	D	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase	1490125..1491417	Azoarcus sp. BH72	4606835
YP_932874.1	CDS	azo1370	NC_008702.1	1491592	1493208	D	Aerotaxis receptor protein,; Specificity unclear; putative aerotaxis receptor protein	1491592..1493208	Azoarcus sp. BH72	4606836
YP_932875.1	CDS	lpdA	NC_008702.1	1493285	1495105	R	Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089); Pyridine nucleotide-disulphide oxidoreductase dimersiation domain (IPR004099); NAD binding site (IPR000205); 2-oxo acid dehydrogenase acetyltransferase, classI (IPR003016) Pfam: Biotin-requiring enzyme; Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide oxidoreductase dimersation domain no TMHs no signal peptide; High confidence in function and specificity; dihydrolipoamide dehydrogenase	complement(1493285..1495105)	Azoarcus sp. BH72	4606837
YP_932876.1	CDS	pdhB	NC_008702.1	1495116	1496804	R	Probable dihydrolipoamide acetyltransferase. Homology to pdhB of A. eutrophus of 62% (sprot|ODP2_ALCEU) THE PYRUVATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF PYRUVATE TO ACETYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF THREE ENZYMATIC COMPONENTS: PYRUVATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2) & LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: 2-Oxo acid dehydrogenase acyltransferase catalytic domain (IPR001078); Type I antifreeze protein (IPR000104); Biotin/Lipoyl attachment (IPR000089); E3 binding domain (IPR004167); 2-Oxo acid dehydrogenase acyltransferase component lipoyl binding site (IPR003016) Pfam: Biotin-requiring enzyme; E3 binding domain; 2-oxo dehydrogenase acyltransferase Tigrfam: BCCP: acetyl-CoA carboxylase biotin carboxyl carrier protein no TMHs no signal peptide; High confidence in function and specificity; dihydrolipoamide acetyltransferase	complement(1495116..1496804)	Azoarcus sp. BH72	4609173
YP_932877.1	CDS	aceE	NC_008702.1	1496825	1499506	R	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1	complement(1496825..1499506)	Azoarcus sp. BH72	4609514
YP_932878.1	CDS	azo1374	NC_008702.1	1499913	1501118	R	This family includes extracellular ligand binding domains of a wide range of receptors and it also includes the bacterial amino acid binding proteins of known structure. Similar to tremblnew|AAR35111 (24%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Family membership; extracellular ligand binding protein	complement(1499913..1501118)	Azoarcus sp. BH72	4609513
YP_932879.1	CDS	azo1375	NC_008702.1	1501285	1503999	D	Putative two-component sensor kinase,; Specificity unclear; putative two-component sensor kinase	1501285..1503999	Azoarcus sp. BH72	4606838
YP_932880.1	CDS	fixJ2	NC_008702.1	1503974	1504612	D	Probable transcriptional regulatory protein,; Specificity unclear; transcriptional regulator	1503974..1504612	Azoarcus sp. BH72	4606839
YP_932881.1	CDS	folD	NC_008702.1	1504697	1505572	D	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase	1504697..1505572	Azoarcus sp. BH72	4608767
YP_932882.1	CDS	purE	NC_008702.1	1505580	1506092	D	Phosphoribosylaminoimidazole carboxylase(AIR carboxylase) (AIRC). InterPro: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; High confidence in function and specificity; phosphoribosylaminoimidazole carboxylase	1505580..1506092	Azoarcus sp. BH72	4608820
YP_932883.1	CDS	purK	NC_008702.1	1506220	1507401	D	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit	1506220..1507401	Azoarcus sp. BH72	4609658
YP_932884.1	CDS	azo1380	NC_008702.1	1507398	1508429	D	Hypothetical protein ywlC. TIGR00057: Sua5/YciO/YrdC/YwlC family; Specificity unclear; hypothetical protein	1507398..1508429	Azoarcus sp. BH72	4609661
YP_932885.1	CDS	carA	NC_008702.1	1508792	1509934	D	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit	1508792..1509934	Azoarcus sp. BH72	4609979
YP_932886.1	CDS	carB	NC_008702.1	1509989	1513216	D	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit	1509989..1513216	Azoarcus sp. BH72	4608414
YP_932887.1	CDS	greA	NC_008702.1	1513213	1513689	D	Transcription elongation factor GreA Transcription elongation factor greA (Transcript cleavage factor greA). Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as greA or greB allows the resumption of elongation from the new 3terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity). Belongs to the greA/greB family. 58% 1. PF03449 GreA_GreB_N; 1. TIGFRAM TIGR01462; greA; 1. PurN: phosphoribosylglycinamide formylt; High confidence in function and specificity; putative transcription elongation factor	1513213..1513689	Azoarcus sp. BH72	4608415
YP_932888.1	CDS	azo1384	NC_008702.1	1513701	1514171	D	Conserved hypothetical membrane protein. Homology to RS03781 of Ralstonia solanacearum of 39% (trembl|Q8XZ81(SRS)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	1513701..1514171	Azoarcus sp. BH72	4608935
YP_932889.1	CDS	azo1385	NC_008702.1	1514202	1514663	R	hypothetical protein	complement(1514202..1514663)	Azoarcus sp. BH72	4606841
YP_932890.1	CDS	FtsJ	NC_008702.1	1514707	1515324	D	Ribosomal RNA large subunit methyltransferase J (EC 2.1.1.-) (rRNA (uridine-2-O-)-methyltransferase) (23S rRNA m2U2552 methyltransferase) (Cell division protein ftsJ homolog). Specifically methylates the uridine in position 2552 of 23S rRNA in the 50S particle; High confidence in function and specificity; ribosomal RNA large subunit methyltransferase J	1514707..1515324	Azoarcus sp. BH72	4606842
YP_932891.1	CDS	FtsH	NC_008702.1	1515440	1517332	D	Cell division protease ftsH. Homology to ftsH of E. coli of 64% (SWISSPROT:FTSH_ECOLI) SEEMS TO ACT AS AN ATP-DEPENDENT ZINC METALLOPEPTIDASE. INVOLVED IN THE DEGRADATION OF SIGMA-32. DEGRADES CARBOXY- TERMINAL-TAGGED CYTOPLASMIC PROTEINS. THESE PROTEINS ARE TAGGED WITH AN 11-AMINO-ACID NONPOLAR DESTABILIZING TAIL VIA A MECHANISM INVOLVING THE 10SA (SSRA) STABLE RNA (By similarity). Pfam: ATPase family associated with various celluar activities;Peptidase family M41 probable signal peptide probable 1 TMH; High confidence in function and specificity; cell division protein FtsH	1515440..1517332	Azoarcus sp. BH72	4608836
YP_932892.1	CDS	folP	NC_008702.1	1517394	1518215	D	Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase). DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide (By similarity).; High confidence in function and specificity; dihydropteroate synthase	1517394..1518215	Azoarcus sp. BH72	4608834
YP_932893.1	CDS	glmM	NC_008702.1	1518249	1519604	D	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase	1518249..1519604	Azoarcus sp. BH72	4608823
YP_932894.1	CDS	pstS2	NC_008702.1	1519717	1520757	D	61% Peri-phosph.IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR00975; 3a0107s03; 1. Signal peptide present.; High confidence in function and specificity; phosphate-binding periplasmic protein	1519717..1520757	Azoarcus sp. BH72	4608891
YP_932895.1	CDS	pstC	NC_008702.1	1520867	1521829	D	part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC	1520867..1521829	Azoarcus sp. BH72	4609644
YP_932896.1	CDS	azo1392	NC_008702.1	1521902	1522681	D	Region start changed from 1521840 to 1521903 (-63 bases); phosphate ABC transporter permease	1521902..1522681	Azoarcus sp. BH72	4609642
YP_932897.1	CDS	pstB	NC_008702.1	1522714	1523478	D	Phosphate import ATP-binding protein pstB (EC 3.6.3.27) (Phosphate- transporting ATPase) (ABC phosphate transporter) (Peripheral membrane protein B). Part of the ABC transporter complex pstSACB (TC 3.A.1.7.1) involved in phosphate import. Responsible for energy coupling to the transport system. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity; phosphate ABC transporter ATP-binding protein	1522714..1523478	Azoarcus sp. BH72	4606843
YP_932898.1	CDS	tpiA	NC_008702.1	1523592	1524320	D	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase	1523592..1524320	Azoarcus sp. BH72	4609641
YP_932899.1	CDS	secG	NC_008702.1	1524363	1524725	D	Protein-export membrane protein secG. Involved in protein export. Participates in an early event of protein translocation (By similarity). Together with SecY and SecG, SecE forms a multimeric channel through which preproteins are translocated, using both proton motive forces and ATP-driven secretion. pfam: preprotein translocase tigerfam: preprotein translocase most propable TMH: 2 no signal peptide InterPro: Preprotein translocase SecG subunit Pfam: secG: preprotein translocase SecG subuni; High confidence in function and specificity; preprotein translocase subunit SecG	1524363..1524725	Azoarcus sp. BH72	4609949
YP_932900.1	CDS	nuoA	NC_008702.1	1524978	1525352	D	NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3). Ndh-1 shuttles electrons from nadh, via fmn and iron- sulfur (fe-s) centers, to quinones in the respiratory chain. the immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (by similarity).; High confidence in function and specificity; putative NADH-ubiquinone oxidoreductase subunit A	1524978..1525352	Azoarcus sp. BH72	4610005
YP_932901.1	CDS	nuoB2	NC_008702.1	1525357	1525833	D	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B	1525357..1525833	Azoarcus sp. BH72	4609418
YP_932902.1	CDS	nuoC	NC_008702.1	1525851	1526456	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C	1525851..1526456	Azoarcus sp. BH72	4609420
YP_932903.1	CDS	nuoD	NC_008702.1	1526449	1527702	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D	1526449..1527702	Azoarcus sp. BH72	4609421
YP_932904.1	CDS	nuoE	NC_008702.1	1527783	1528262	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E	1527783..1528262	Azoarcus sp. BH72	4609422
YP_932905.1	CDS	nuoF	NC_008702.1	1528259	1529578	D	NADH-quinone oxidoreductase chain F (EC 1.6.99.5) (NADH dehydrogenase I chain F) (NDH-1 chain F). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit gnd_rel: 6-phosphogluconate dehydrogenas; High confidence in function and specificity; putative NADH-ubiquinone oxidoreductase subunit F	1528259..1529578	Azoarcus sp. BH72	4609423
YP_932906.1	CDS	nuoG	NC_008702.1	1529572	1531887	D	Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G	1529572..1531887	Azoarcus sp. BH72	4609424
YP_932907.1	CDS	nuoH	NC_008702.1	1531887	1532936	D	NADH-quinone oxidoreductase chain H (EC 1.6.99.5) (NADH dehydrogenase I chain H) (NDH-1 chain H). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). InterPro: Respiratory-chain NADH dehydrogenase subunit 1 nup: nucleoside transporter; High confidence in function and specificity; putative NADH-ubiquinone oxidoreductase subunit H	1531887..1532936	Azoarcus sp. BH72	4609425
YP_932908.1	CDS	nuoI	NC_008702.1	1532947	1533432	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I	1532947..1533432	Azoarcus sp. BH72	4609426
YP_932909.1	CDS	nuoJ	NC_008702.1	1533469	1534071	D	NADH-quinone oxidoreductase chain J (EC 1.6.99.5) (NADH dehydrogenase I chain J) (NDH-1 chain J). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. MIP: MIP family channel proteins; High confidence in function and specificity; NADH-ubiquinone oxidoreductase subunit J	1533469..1534071	Azoarcus sp. BH72	4609427
YP_932910.1	CDS	nuoK	NC_008702.1	1534128	1534433	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K	1534128..1534433	Azoarcus sp. BH72	4609428
YP_932911.1	CDS	nuoL	NC_008702.1	1534446	1536470	D	NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH dehydrogenase I chain L) (NDH-1 chain L). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient (By similarity). 2A0310: amino acid permease (yeast); High confidence in function and specificity; NADH-ubiquinone oxidoreductase subunit L	1534446..1536470	Azoarcus sp. BH72	4609429
YP_932912.1	CDS	nuoM	NC_008702.1	1536546	1538027	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M	1536546..1538027	Azoarcus sp. BH72	4609430
YP_932913.1	CDS	nuoN	NC_008702.1	1538065	1539540	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N	1538065..1539540	Azoarcus sp. BH72	4609431
YP_932914.1	CDS	azo1410	NC_008702.1	1539628	1540179	D	ADPribose diphosphatase. ACTIVE ON ADENOSINE(5)TRIPHOSPHO(5)ADENOSINE (AP3A) ADP-RIBOSE NADH ADENOSINE(5)DIPHOSPHO(5)ADENOSINE (AP2A). InterPro: NUDIX hydrolase TIGR00052: conserved hypothetical protein.; High confidence in function and specificity; ADP-ribose diphosphatase	1539628..1540179	Azoarcus sp. BH72	4609432
YP_932915.1	CDS	azo1411	NC_008702.1	1540276	1543152	R	Conserved hypothetical ribonucleoside reductase. Homology to nrdE of C. violaceum of 62% (trembl|Q7NY29). Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides precursors that are necessary for DNA synthesis (By similarity). InterPro: Ribonucleotide reductase large subunit (IPR000788) Pfam: Ribonucleotide reductase, all-alpha domein; Ribonucleotide reductase, barrel domain no signal peptide no TMHs; High confidence in function and specificity; putative ribonucleoside reductase	complement(1540276..1543152)	Azoarcus sp. BH72	4606844
YP_932916.1	CDS	hoxF	NC_008702.1	1543481	1545289	D	Probable hydrogen dehydrogenase, alpha subunit. Homology to hoxF of A. eutrophus of 41% (sprot|HOXF_ALCEU). SUBUNITS ALPHA AND GAMMA OF HOXS CONSTITUTE AN NADH-OXIDOREDUCTASE. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); Respiratory-chain NADH dehydrogenase 24 Kd subunit (IPR002023) Pfam: Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit no signal peptide no TMHs; High confidence in function and specificity; hydrogen dehydrogenase subunit alpha	1543481..1545289	Azoarcus sp. BH72	4606845
YP_932917.1	CDS	hoxU	NC_008702.1	1545286	1545990	D	Probable hydrogen dehydrogenase, gamma subunit. Homology to hoxU of A. eutrophus of 40% (pir|B35385(PIR). Binds 3 4Fe-4S clusters per subunit (Potential). Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity; hydrogen dehydrogenase subunit gamma	1545286..1545990	Azoarcus sp. BH72	4609019
YP_932918.1	CDS	hoxY	NC_008702.1	1545987	1546559	D	Probable hydrogen dehydrogenase, delta subunit. Homology to hoxY of a. eutrophus of 45% (sprot|HOXY_ALCEU). InterPro: Respiratory-chain NADH dehydrogenase 20 Kd subunit Pfam: NADH ubiquinone oxidoreductase, 20 kD subunit no signal peptie no TMHs; High confidence in function and specificity; hydrogen dehydrogenase subunit delta	1545987..1546559	Azoarcus sp. BH72	4609022
YP_932919.1	CDS	hoxH	NC_008702.1	1546567	1548030	D	Probable hydrogen dehydrogenase, beta subunit. Homology to hoxH of a. eutrophus of 48% (sprot|HOXH_ALCEU). Pfam: Nickel-dependent hydrogenase no signal peptide no TMHs; High confidence in function and specificity; hydrogen dehydrogenase subunit beta	1546567..1548030	Azoarcus sp. BH72	4609023
YP_932920.1	CDS	azo1416	NC_008702.1	1548062	1548553	D	conserved hypothetical protein. Homology to an orf of R. capsulata of 42% (trembl|Q9XBW7). Tigrfam: hycI: hydrogenase maturation protease no signal peptide no TMHs; hypothetical protein	1548062..1548553	Azoarcus sp. BH72	4609020
YP_932921.1	CDS	azo1417	NC_008702.1	1548563	1549420	R	Conserved hypothetical protein. Homology to GSU0904 of Geobacter sulfurreducens of 31% (gnl|keqq|gsu:GSU0904(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1548563..1549420)	Azoarcus sp. BH72	4606846
YP_932922.1	CDS	czcD2	NC_008702.1	1549449	1550681	R	CzcD: Members of this family are integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. 41% Cation_efflux. Pfam:PF01545; Cation_efflux; 1. TMhelix:6.; High confidence in function and specificity; putative cobalt-zinc-cadmium resistance protein	complement(1549449..1550681)	Azoarcus sp. BH72	4606847
YP_932923.1	CDS	azo1419	NC_008702.1	1550659	1551510	D	Conserved hypothetical protein. Homology to Rsc1208 of R. solanacearum of 45% (trembl|Q8Y036). InterPro: AP endonucleases family 1 (IPR000097) tigrfam: xth: exodeoxyribonuclease III (xth) All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family 1 no signal peptide no TMHs; hypothetical protein	1550659..1551510	Azoarcus sp. BH72	4608574
YP_932924.1	CDS	azo1420	NC_008702.1	1551523	1552323	R	Conserved hypothetical membrane protein. Homology to CV3790 of Chromobacterium violaceum of 42% (trembl|Q7NRJ1). No domains predicted. no signal peptide 5 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1551523..1552323)	Azoarcus sp. BH72	4606848
YP_932925.1	CDS	azo1421	NC_008702.1	1552425	1553234	R	TREMBLNEW:CAE27009: Probable carboxylesterase, 50% identity, 60% similarity. Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). InterPro: Alpha/beta hydrolase fold: IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1 InterPro: Alpha/beta hydrolase fold kdgT: 2-keto-3-deoxygluconate permease; Family membership; carboxylesterase	complement(1552425..1553234)	Azoarcus sp. BH72	4606849
YP_932926.1	CDS	azo1422	NC_008702.1	1553238	1554542	R	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase	complement(1553238..1554542)	Azoarcus sp. BH72	4606850
YP_932927.1	CDS	azo1423	NC_008702.1	1554602	1554817	R	Conserved hypothetical protein. Homology to bsr7110 of B.japonicum of 48% (tremble:Q89EH5). Pfam:Protein of unknown function (DUF465) Family members are found in small bacterial proteins, and also in the heavy chains of eukaryotic myosin and kinesin, C terminal of the motor domain (Myosin Myosin_head, Kinesin Kinesin). Members of this family may form coiled coil structures. No signal peptide present. No TMH; hypothetical protein	complement(1554602..1554817)	Azoarcus sp. BH72	4606851
YP_932928.1	CDS	greB	NC_008702.1	1554874	1555542	D	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB	1554874..1555542	Azoarcus sp. BH72	4606852
YP_932929.1	CDS	htpG	NC_008702.1	1555626	1557557	D	molecular chaperone; heat shock protein 90	1555626..1557557	Azoarcus sp. BH72	4608936
YP_932930.1	CDS	yadQ	NC_008702.1	1557627	1558949	R	Chloride channel protein, yadQ.In E.coli the product of yadQ gene is named EriC.This family of ion channels contains 10 or 12 transmembrane helices. Each protein forms a single pore. It has been shown that some members of this family form homodimers. These proteins contain two CBS domains. Voltage-gated ClC-type chloride channel clcA. Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation as part of the extreme acid resistance (XAR) response (By similarity).; High confidence in function and specificity; putative chloride channel protein	complement(1557627..1558949)	Azoarcus sp. BH72	4609039
YP_932931.1	CDS	mexR	NC_008702.1	1559286	1559798	D	Putative MarR-family transcriptional regulator,; Family membership; MarR family transcriptional regulator	1559286..1559798	Azoarcus sp. BH72	4610136
YP_932932.1	CDS	azo1428	NC_008702.1	1560019	1560789	D	Conserved hypothetical flavoprotein. Homology to rsc2212 of P. solanacearum of 59% (trembl|Q8XXA4). Pfam: Methallo-beta-lactamase no signal peptide no TMHs; Conserved hypothetical protein; flavoprotein	1560019..1560789	Azoarcus sp. BH72	4609214
YP_932933.1	CDS	azo1429	NC_008702.1	1560826	1562004	R	Conserved hypothetical protein, 63% Identitcal (77% similarity) to TrEMBL;Q8Y0P7,65% identity to TrEMBL;Q7WCK6. Most good homologous hits do not have the same VWA domain represented by this. Has PF05762(IPR008912):VWA domain containing CoxE-like protein;This family is annotated by SMART as containing a VWA type domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria. No Signal peptide or TMH reported present.; Function unclear; hypothetical protein	complement(1560826..1562004)	Azoarcus sp. BH72	4606853
YP_932934.1	CDS	azo1430	NC_008702.1	1562015	1563343	R	Conserved hypothetical secreted protein. Homology to TdenA01001626 of Thiobacillus denitrificans of 32% (gi|52006684|ref|ZP_00334063.1|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(1562015..1563343)	Azoarcus sp. BH72	4606854
YP_932935.1	CDS	azo1431	NC_008702.1	1563353	1564201	R	TREMBL: Q8Y0P5 : 81% identity, 90% similarity. Probable Cell division protein ftsH homolog (EC 3.4.24.-). InterPro:IPR003593; AAA_ATPase. IPR003959; AAA_ATPase_centr. Pfam: PF00004; AAA; ATPase family associated with various SMART: SM00382; AAA; Absence of transmembrane helices (TMHMM predicted) NON secretory protein ruvB: Holliday junction DNA helicase Ru; Specificity unclear; hypothetical protein	complement(1563353..1564201)	Azoarcus sp. BH72	4606855
YP_932936.1	CDS	azo1432	NC_008702.1	1564276	1564599	D	Conserved hypothetical cytochrome c-type protein. Homology to rsc0999 of R. solanacearum of 62% (trembl|Q8Y0P4). Pfam: Cytochrome c signal peptide no TMHs; Conserved hypothetical protein; cytochrome c-type protein	1564276..1564599	Azoarcus sp. BH72	4606856
YP_932937.1	CDS	azo1433	NC_008702.1	1564596	1564937	D	Conserved hypothetical cytochrome c-type protein. Homology to ebA4874 of Azoarcus_EbN1 of 60% (gnl|keqq|eba:ebA4874(KEGG)). Interpro: cytochrome c,classI (IPRoo3088); cytochrome c, class IC (IPR008168). Pfam: cytochrome C. singal peptide. no TMHs; Conserved hypothetical protein; cytochrome c-type protein	1564596..1564937	Azoarcus sp. BH72	4606857
YP_932938.1	CDS	azo1434	NC_008702.1	1565036	1565467	R	Hypothetical protein similar by 78% to RSc1001 [RS04291] [Ralstonia solanacearum(Pseudomonas solanacearum)].TrEMBL Q8Y0P2. No Signal Peptide Reported No TMH Reported.; hypothetical protein	complement(1565036..1565467)	Azoarcus sp. BH72	4606858
YP_932939.1	CDS	nth	NC_008702.1	1565496	1566137	R	Endonuclease III . Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines thymines and guanines. Acts on a damaged strand 5 from the damaged site (By similarity). TIGRFAM: comE: comEA protein; High confidence in function and specificity; DNA-(apurinic or apyrimidinic site) lyase	complement(1565496..1566137)	Azoarcus sp. BH72	4606859
YP_932940.1	CDS	rnfE2	NC_008702.1	1566139	1566852	R	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex subunit RsxE	complement(1566139..1566852)	Azoarcus sp. BH72	4609412
YP_932941.1	CDS	rnfG2	NC_008702.1	1566849	1567523	R	Putative electron transport complex protein rnfG. Homolog to rnfG of R. capsulata of 36% (sprot|RNFG_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. signal peptide no TMHs; High confidence in function and specificity; putative electron transport complex protein RnfG	complement(1566849..1567523)	Azoarcus sp. BH72	4609749
YP_932942.1	CDS	rnfD2	NC_008702.1	1567520	1568527	R	Putative electron transport complex protein rnfD. Homology to rnfD of R. capsulatus of 33% (sprot|RNFD_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity). InterPro: NQR2 and RnfD/E related proteins (IPR004338) Pfam: NQR2, RnfD, RnfE family signal peptide probable 6 TMHs; Family membership; putative electron transport complex protein RnfD	complement(1567520..1568527)	Azoarcus sp. BH72	4609751
YP_932943.1	CDS	rnfC2	NC_008702.1	1568524	1570182	R	part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC	complement(1568524..1570182)	Azoarcus sp. BH72	4609747
YP_932944.1	CDS	rnfB2	NC_008702.1	1570179	1570730	R	part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB	complement(1570179..1570730)	Azoarcus sp. BH72	4609745
YP_932945.1	CDS	rnfA2	NC_008702.1	1570739	1571323	R	Probable electron transport complex protein RnfA. Homology to rnfA of R. capsultatus of 57% (RNFA_RHOCA). Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase. Required for stable existence of rnfB and rnfC. InterPro: RnfA-Nqr electron transport subunit (IPR003667) Pfam: Rnf-Nqr subunit, membrane protein no signal peptide 6 TMHs; High confidence in function and specificity; electron transport complex promplex protein RnfA	complement(1570739..1571323)	Azoarcus sp. BH72	4609743
YP_932946.1	CDS	azo1442	NC_008702.1	1571407	1572036	R	HNH family of nucleases is found in bacteria,viruses, eukaryotes and includes yeast intron 1 protein,MutS, and bacterial colicins and pyocins. InterPro (IPR003615): HNH nuclease InterPro (IPR002711): HNH endonuclease. Pfam (PF01844): HNH endonuclease.; Family membership; putative nuclease	complement(1571407..1572036)	Azoarcus sp. BH72	4609741
YP_932947.1	CDS	azo1443	NC_008702.1	1572157	1572723	R	Conserved hypothetical NUDIX hydrolase. Homology to ne1158 of N. europaea of 58% (trembl|Q82VD6) The generic name 'NUDIX hydrolases' (NUcleoside DIphosphate linked to some other moiety X) has been coined for this domain family. The family can be divided into a number of subgroups, of which MutT anti-mutagenic activity represents only one type; most of the rest hydrolyse diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). InterPro: NUDIX hydrolase (IPR000086) Pfam: MutT-like domain no signal peptide no TMHs; Function unclear; NUDIX hydrolase	complement(1572157..1572723)	Azoarcus sp. BH72	4606860
YP_932948.1	CDS	mmoQ	NC_008702.1	1572893	1574863	D	Probable response regulator,; Family membership; response regulator	1572893..1574863	Azoarcus sp. BH72	4606861
YP_932949.1	CDS	azo1445	NC_008702.1	1574860	1576590	D	EAL/GGDEF-domain containing signaling protein,; Conserved hypothetical protein; EAL/GGDEF domain-containing protein	1574860..1576590	Azoarcus sp. BH72	4609229
YP_932950.1	CDS	flhD	NC_008702.1	1576751	1577074	D	Flagellar transcriptional activator,flhD. This family consists of several bacterial flagellar transcriptional activator proteins. FlhD combines with FlhC to form a regulatory complex in Escherichia coli. This complex has been shown to be a global regulator involved in many cellular processes as well as a flagellar transcriptional activator TrEMBL: Q82SD3 InterPro:IPR007911 Pfam:PF05247 FUNCTION: Transcriptional activator. Involved in the regulation of a number of genetic systems (By similarity). SUBUNIT: Homodimer; disulfide-linked. Forms a heterotetrameric complex with two subunits of flhC (By similarity). SUBCELLULAR LOCATION: Cytoplasmic (By similarity). Belongs to the flhD family. No Signal Peptide. No TMH Present.; Family membership; flagellar transcriptional activator FlhD	1576751..1577074	Azoarcus sp. BH72	4606862
YP_932951.1	CDS	flhC	NC_008702.1	1577079	1577633	D	with FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC	1577079..1577633	Azoarcus sp. BH72	4608792
YP_932952.1	CDS	motA2	NC_008702.1	1577773	1578627	D	Flagellar motor protein MotA (Chemotaxis motA protein). Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). signal peptide probable 4 TMHs; High confidence in function and specificity; flagellar motor protein MotA	1577773..1578627	Azoarcus sp. BH72	4608791
YP_932953.1	CDS	motB2	NC_008702.1	1578688	1579761	D	Flagellar motor protein MotB (Chemotaxis motB protein. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall. Pfam: OmpA family no signal peptide probable 1 TMHs; High confidence in function and specificity; flagellar motor protein MotB	1578688..1579761	Azoarcus sp. BH72	4609261
YP_932954.1	CDS	cheY2	NC_008702.1	1579813	1580229	D	Putative chemotaxis response regulator,; Family membership; putative chemotaxis response regulator	1579813..1580229	Azoarcus sp. BH72	4609263
YP_932955.1	CDS	cheA2	NC_008702.1	1580242	1582332	D	Chemotaxis protein cheA; INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY. EMBL AE005411; AAG56878.1; -. AP002559; BAB36021.1; -. PIR B85802; B85802. F90953; F90953. InterPro IPR003594; ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR000629; DEAD_box. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR009082; His_kin_homodim. IPR008207; Hpt. IPR008208; Hpt_N. Pfam PF01584; CheW; 1. PF02895; H-kinase_dim; 1. PF02518; HATPase_c; 1. PF01627; Hpt; 1. PRINTS PR00344; BCTRLSENSOR.; High confidence in function and specificity; chemotaxis protein cheA	1580242..1582332	Azoarcus sp. BH72	4608477
YP_932956.1	CDS	cheW2	NC_008702.1	1582399	1582908	D	Positive regulator of CheA protein activity,; High confidence in function and specificity; positive regulator of CheA protein activity	1582399..1582908	Azoarcus sp. BH72	4608465
YP_932957.1	CDS	tsr	NC_008702.1	1582905	1584779	D	The Escherichia coli chemoreceptor Tsr mediates tactic responses to serine, repellents, and changes in temperature. Similar to sprot|MCP1_ECOLI (31%)and to trembl|Q7NSI6 (36%). Bacterial chemotactic-signal transducers are proteins that respond to changes in the concentration of attractants and repellents in the environment, and transduce a signal from the outside to the inside of the cell. These proteins undergo two covalent modifications: deamidation and reversible methylation. Attractants increase the level of methylation while repellents decrease it. The methyl groups are added by the methyl-transferase cheR and are removed by the methylesterase cheB. Pfam (PF00015): MCPsignal TMHMM reporting two TMH.; Specificity unclear; putative serine chemoreceptor protein	1582905..1584779	Azoarcus sp. BH72	4608475
YP_932958.1	CDS	tcp	NC_008702.1	1584776	1587298	D	Salmonella typhimurium shows an attractant response to citrate and a repellent response to phenol, and a chemoreceptor mediating these responses has been identified and named Tcp (taxis to citrate and away from phenol). Similar to sprot|MCPC_SALTY (32%)and to trembl|Q82TM2. InterPro (IPR004089): Bacterial chemotaxis sensory transducer InterPro (IPR003660): HAMP InterPro (IPR004090): Methyl-accepting chemotaxis protein InterPro (IPR001610): PAC InterPro (IPR000014): PAS_domain Pfam (PF00672): HAMP Pfam (PF00015): MCPsignal Pfam (PF00785): PAC Pfam (PF00989):PAS TIGRFAMs (TIGR00229): sensory_box TMHMM reporting two TMH.; Specificity unclear; putative citrate chemoreceptor protein	1584776..1587298	Azoarcus sp. BH72	4610046
YP_932959.1	CDS	cheR2	NC_008702.1	1587301	1588254	D	Methylase of chemotaxis methyl-accepting proteins,; High confidence in function and specificity; chemotaxis protein methyltransferase	1587301..1588254	Azoarcus sp. BH72	4609924
YP_932960.1	CDS	cheB2	NC_008702.1	1588263	1589384	D	Chemotaxis response regulator protein-glutamate methylesterase, catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by cheR.; High confidence in function and specificity; protein glutamate-methylesterase	1588263..1589384	Azoarcus sp. BH72	4608471
YP_932961.1	CDS	azo1457	NC_008702.1	1589532	1591208	D	Methyl-accepting chemotaxis protein,; Specificity unclear; methyl accepting chemotaxis protein	1589532..1591208	Azoarcus sp. BH72	4608468
YP_932962.1	CDS	cheV1	NC_008702.1	1591411	1592376	D	Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION.; High confidence in function and specificity; chemotaxis protein CheV-like	1591411..1592376	Azoarcus sp. BH72	4606863
YP_932963.1	CDS	cheV2	NC_008702.1	1592386	1593342	D	Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION.; High confidence in function and specificity; chemotaxis protein CheV-like	1592386..1593342	Azoarcus sp. BH72	4608472
YP_932964.1	CDS	cheY3	NC_008702.1	1593373	1593774	D	Chemotaxis response regulator, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. Chemotaxis protein cheY. Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form cheY exhibits enhanced binding to a switch component fliM at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity).; High confidence in function and specificity; chemotaxis response regulator	1593373..1593774	Azoarcus sp. BH72	4608473
YP_932965.1	CDS	cheZ	NC_008702.1	1593809	1594702	D	cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ	1593809..1594702	Azoarcus sp. BH72	4608478
YP_932966.1	CDS	cheA3	NC_008702.1	1594779	1596674	D	Chemotaxis histidine kinase,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY.; High confidence in function and specificity; chemotaxis protein cheA	1594779..1596674	Azoarcus sp. BH72	4608479
YP_932967.1	CDS	azo1463	NC_008702.1	1596794	1597105	D	Hypothetical protein, 31% identity (47% similarity) to TrEMBL:Q8KLF6 Coils2 program reports the presence of coiled-coil.; hypothetical protein	1596794..1597105	Azoarcus sp. BH72	4608466
YP_932968.1	CDS	tal	NC_008702.1	1597121	1598236	R	catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase	complement(1597121..1598236)	Azoarcus sp. BH72	4606864
YP_932969.1	CDS	azo1465	NC_008702.1	1598208	1598990	R	tRNA pseudouridine synthase C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; High confidence in function and specificity; ORF3; hypothetical protein	complement(1598208..1598990)	Azoarcus sp. BH72	4609913
YP_932970.1	CDS	azo1466	NC_008702.1	1599073	1599657	R	SodB: Superoxide dismutase [Fe] (EC 1.15.1.1).Catalyse the conversion of superoxide radicals to molecular oxygen. Their function is to destroy the radicals that are normally produced within cells and are toxic to biological systems. 76% SODismutase. Pfam:PF02777; Sod_Fe_C; 1. PF00081; Sod_Fe_N; 1.; High confidence in function and specificity; putative superoxide dismutase	complement(1599073..1599657)	Azoarcus sp. BH72	4606865
YP_932971.1	CDS	xseA	NC_008702.1	1599814	1601193	R	Probable exodeoxyribonuclease VII large subunit . Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides which are then degraded further into small acid-soluble oligonucleotides (By similarity). TIGRFAM: xseA: exodeoxyribonuclease VII large.; High confidence in function and specificity; exodeoxyribonuclease VII	complement(1599814..1601193)	Azoarcus sp. BH72	4606866
YP_932972.1	CDS	exbB3	NC_008702.1	1601484	1602092	D	conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership; biopolymer transport protein ExbB	1601484..1602092	Azoarcus sp. BH72	4610129
YP_932973.1	CDS	exbD4	NC_008702.1	1602104	1602526	D	Putative biopolymer transport exbD2 protein. Homology to exbD2 of V. choloera of 31% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership; putative biopolymer transport protein ExbD	1602104..1602526	Azoarcus sp. BH72	4608698
YP_932974.1	CDS	lpxK	NC_008702.1	1602530	1603555	D	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase	1602530..1603555	Azoarcus sp. BH72	4608703
YP_932975.1	CDS	ycaR	NC_008702.1	1603536	1603724	D	Putative inner membrane protein [ycaR], 66% identity (85% similarity) to SwissProt;P75844(E.coli) and 65% identity to TrEMBL;Q7CQT7. Has PF03966:Protein of unknown function (DUF343);This family of short proteins have no known function. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus contains the strongest conservation. Signal Peptide or TMH not present.; Function unclear; hypothetical protein	1603536..1603724	Azoarcus sp. BH72	4609179
YP_932976.1	CDS	kdsB	NC_008702.1	1603733	1604506	D	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase	1603733..1604506	Azoarcus sp. BH72	4610152
YP_932977.1	CDS	adk	NC_008702.1	1604626	1605279	D	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase	1604626..1605279	Azoarcus sp. BH72	4609104
YP_932978.1	CDS	pfkA	NC_008702.1	1605395	1606660	D	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase	1605395..1606660	Azoarcus sp. BH72	4608282
YP_932979.1	CDS	ggt	NC_008702.1	1606678	1608399	D	Gamma-glutamyltranspeptidase catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Similar to trembl|Q88H30 (43%)and to trembl|Q8UJH0 (36%). TIGRfam (TIGR00066): Gamma-glutamyltranspeptidase Pfam (PF01019): Gamma-glutamyltranspeptidase SignalP reporting Signal peptide.; Specificity unclear; Ggt protein	1606678..1608399	Azoarcus sp. BH72	4609528
YP_932980.1	CDS	azo1476	NC_008702.1	1608393	1610963	R	Conserved hypothetical membrane protein,; Conserved hypothetical protein; hypothetical protein	complement(1608393..1610963)	Azoarcus sp. BH72	4608875
YP_932981.1	CDS	drgA	NC_008702.1	1611123	1611704	R	Putative NAD(P)H oxidoreductase HI1544 (EC 1.6.5.2 ). trembl:Q88J60: 64% identity; 80% similarity This family consists of bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC: 1.6.5.2 that catalyses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species [1]. This enzyme uses a FAD co-factor InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 SignalP predicted signal peptide present No transmembrane helices (TMHMM predicted); High confidence in function and specificity; NAD(P)H quinone oxidoreductase	complement(1611123..1611704)	Azoarcus sp. BH72	4606867
YP_932982.1	CDS	azo1478	NC_008702.1	1611764	1612186	R	Probable MerR-family transcriptional regulator,; Family membership; MerR family transcriptional regulator	complement(1611764..1612186)	Azoarcus sp. BH72	4608651
YP_932983.1	CDS	gltX	NC_008702.1	1612279	1613682	D	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase	1612279..1613682	Azoarcus sp. BH72	4606868
YP_932984.1	CDS	azo1480	NC_008702.1	1613749	1614060	R	Probable Nitrogen regulatory protein P-II 1. Could be involved in the regulation of nitrogen fixation.Belongs to the P(II) protein family.55% similarity with Methanothermobacter thermautotrophicus,TrEMBL:O26758 Pfam:PF00543, InterPro:IPR002332,IPR002187 No Signal peptide present. No TMH reported.; nitrogen regulatory protein P-II	complement(1613749..1614060)	Azoarcus sp. BH72	4608918
YP_932985.1	CDS	azo1481	NC_008702.1	1614063	1615001	R	Conserved hypothetical membrane protein. Homology to ttc139 of T. termophilus of 49% (trembl|Q72LC0). no domains no singal peptide 8 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1614063..1615001)	Azoarcus sp. BH72	4606869
YP_932986.1	CDS	mnmC	NC_008702.1	1615045	1616952	R	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase	complement(1615045..1616952)	Azoarcus sp. BH72	4606870
YP_932987.1	CDS	azo1483	NC_008702.1	1617116	1619113	R	Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its activity. Has PF00149,Calcineurin-like phosphoesterase; IPR004843, M-pesterase; This family includes a diverse range of phosphoesterases,including protein phosphoserine phosphatases,nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD P13457 or yeast MRE11 P32829. The most conserved regions in this superfamily centre around the metal chelating residues.; High confidence in function and specificity; 5'-nucleotidase	complement(1617116..1619113)	Azoarcus sp. BH72	4610171
YP_932988.1	CDS	nucH	NC_008702.1	1619180	1622011	R	Putative extracellular nuclease. Homology to nucH of A. hydrophila of 33% (trembl|Q44070) Tigrfam: xth: exodeoxyribonuclease III (xth) Pfam: Endonuclease/ Exonuclease/ Phoshatase family singal peptide no TMHs; Family membership; putative extracellular nuclease	complement(1619180..1622011)	Azoarcus sp. BH72	4606871
YP_932989.1	CDS	azo1485	NC_008702.1	1622218	1622907	D	Conserved hypothetical membrane protein. Homology ebA4071 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA4071(KEGG)). Has PF06930, Protein of unknown function (DUF1282); IPR009698; This family consists of several hypothetical proteins of around 200 residues in length. The function of this family is unknown although a number of family members are thought to be putative membrane proteins. no signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	1622218..1622907	Azoarcus sp. BH72	4609417
YP_932990.1	CDS	azo1486	NC_008702.1	1622923	1624122	R	Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs.; Conserved hypothetical protein; putative signaling protein	complement(1622923..1624122)	Azoarcus sp. BH72	4606872
YP_932991.1	CDS	lysS	NC_008702.1	1624335	1625837	R	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase	complement(1624335..1625837)	Azoarcus sp. BH72	4606873
YP_932992.1	CDS	azo1488	NC_008702.1	1625995	1626372	D	Conserved hypothetical protein. Homology to Daro03003756 of Dechloromonas aromatica of 53% (gi|41722684|ref|ZP_00149673.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	1625995..1626372	Azoarcus sp. BH72	4609188
YP_932993.1	CDS	azo1489	NC_008702.1	1626384	1626902	R	Hypothetical protein CT2219. SPROT:Q8KAE4: 65% identity; 78% similarity. TREMBL:Q7NS63: 60% identity, 72% similarity putative ACR related to the C-terminal domain of histone macroH2A1 This domain is found in a number of protein associated with DNA and/or RNA unwinding InterPro; IPR002589; A1pp. Pfam; PF01661; A1pp; 1. SMART; SM00506; A1pp non-secretory protein with no signal peptide (SignalP predicted). No transmembrane helices (TMHMM predicted); Function unclear; hypothetical protein	complement(1626384..1626902)	Azoarcus sp. BH72	4606874
YP_932994.1	CDS	azo1490	NC_008702.1	1627018	1630287	R	Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein; putative signaling protein	complement(1627018..1630287)	Azoarcus sp. BH72	4606875
YP_932995.1	CDS	divK	NC_008702.1	1630292	1630687	R	Probable polar differentiation response regulator,; Family membership; polar differentiation response regulator	complement(1630292..1630687)	Azoarcus sp. BH72	4606876
YP_932996.1	CDS	divJ	NC_008702.1	1630684	1632525	R	Putative histidine protein kinase,; Specificity unclear; putative histidine protein kinase	complement(1630684..1632525)	Azoarcus sp. BH72	4608623
YP_932997.1	CDS	azo1493	NC_008702.1	1632830	1634692	R	Conserved hypothetical membrane protein. Homology to Avar03001212 of Anabaena variabilis of 34% (gi|53765559|ref|ZP_00161954.2|(NBCI ENTREZ)). Pfam: Peptidase family M48. 2 TMHs. no signal peptide; Conserved hypothetical protein; hypothetical protein	complement(1632830..1634692)	Azoarcus sp. BH72	4608622
YP_932998.1	CDS	azo1494	NC_008702.1	1634819	1637611	R	Similarity to hypothetical protein in C. violaceum.; hypothetical protein	complement(1634819..1637611)	Azoarcus sp. BH72	4606877
YP_932999.1	CDS	azo1495	NC_008702.1	1637617	1638315	R	Conserved hypothetical protein. Homology to CV0860 of Chromobacterium violaceum of 50% (trembl: Q7NZR1). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1637617..1638315)	Azoarcus sp. BH72	4606878
YP_933000.1	CDS	azo1496	NC_008702.1	1638326	1639639	R	Conserved Hypothetical protein Signal Peptide present. Has Prosite PS00380; RHODANESE_1; Rhodanese (thiosulfate sulfurtransferase) (EC 2.8.1.1)is an enzyme which catalyzes the transfer of the sulfane atom of thiosulfate to cyanide, to form sulfite and thiocyanate. In vertebrates, rhodanese is a mitochondrial enzyme of about 300 amino-acid residues involved in forming iron-sulfur complexes and cyanide detoxification. A cysteine residue takes part in the catalytic mechanism.; hypothetical protein	complement(1638326..1639639)	Azoarcus sp. BH72	4606879
YP_933001.1	CDS	prfB	NC_008702.1	1639694	1640815	R	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2	complement(1639694..1640815)	Azoarcus sp. BH72	4606880
YP_933002.1	CDS	azo1498	NC_008702.1	1640905	1641321	D	Conserved hypothetical membrane protein Homology to an orf of C. violaceum of 41% (trembl|Q7NSF3(SRS)) No domains predicted Signal Peptide present. TMHMM2 reporting 2 TMH's present.; Conserved hypothetical protein; hypothetical protein	1640905..1641321	Azoarcus sp. BH72	4609624
YP_933003.1	CDS	azo1499	NC_008702.1	1641332	1641760	R	TREMBL:Q8XSIO: 58% identity, 73% similarity Hypothetical HIT-like protein Rv0759c/MT0784/Mb0782c. InterPro:IPR001310; HIT. Pfam: PF01230; HIT; 1. PRINTS: PR00332; HISTRIAD InterPro: HIT (Histidine triad) family hupD: hydrogenase expression/formation pr; Family membership; HIT family protein	complement(1641332..1641760)	Azoarcus sp. BH72	4606881
YP_933004.1	CDS	azo1500	NC_008702.1	1641939	1642796	D	Hypothetical secreted protein. Weak homology with hits in the database. Signal Peptide present. No domains predicted. No TMHs; hypothetical protein	1641939..1642796	Azoarcus sp. BH72	4606882
YP_933005.1	CDS	azo1501	NC_008702.1	1642934	1643425	D	Hypothetical protein. No homology to the data bank. Has 2 copies of SMART;SM00671, SEL1, Sel1-like repeats.These represent a subfamily of TPR (tetratricopeptide repeat) sequences. No TMHs. No signal peptide.; hypothetical protein	1642934..1643425	Azoarcus sp. BH72	4606883
YP_933006.1	CDS	azo1502	NC_008702.1	1643422	1643817	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 3 TMHs; hypothetical protein	1643422..1643817	Azoarcus sp. BH72	4606884
YP_933007.1	CDS	azo1503	NC_008702.1	1644105	1644740	R	Putative two-component response regulator,; Family membership; putative two-component response regulator	complement(1644105..1644740)	Azoarcus sp. BH72	4606885
YP_933008.1	CDS	moxY	NC_008702.1	1644737	1646212	R	Putative two-component sensor histidine kinase,; Specificity unclear; putative two-component sensor histidine kinase	complement(1644737..1646212)	Azoarcus sp. BH72	4606886
YP_933009.1	CDS	recJ	NC_008702.1	1646272	1647963	R	Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-). SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE. REQUIRED FOR MANY TYPES OF RECOMBINATIONAL EVENTS ALTHOUGH THE STRINGENCY OF THE REQUIREMENT FOR RECJ APPEARS TO VARY WITH THE TYPE OF RECOMBINATIONAL EVENT MONITORED AND THE OTHER RECOMBINATION GENE PRODUCTS WHICH ARE AVAILABLE. InterPro: Single-stranded-DNA-specific exonuclease RecJ. recJ: single-stranded-DNA-specific exo.; High confidence in function and specificity; single-stranded-DNA-specific exonuclease	complement(1646272..1647963)	Azoarcus sp. BH72	4609266
YP_933010.1	CDS	azo1506	NC_008702.1	1647960	1649036	R	Conserved hypothetical protein. Homology to CV2476 of C.violaceum of 38% (tremble:Q7NV68) No domains predicted. No signal peptide or TMH present.; hypothetical protein	complement(1647960..1649036)	Azoarcus sp. BH72	4609707
YP_933011.1	CDS	azo1507	NC_008702.1	1649253	1651382	D	Conserved hypothetical protein. Homology to cv1738 of C. violaceum (sprot|YH38_CHRVO) InterPro: Uncharacterized protein family UPF0004 (IPR005839) no signal peptide no TMHs TIGR00089: conserved hypothetical prote; hypothetical protein	1649253..1651382	Azoarcus sp. BH72	4606887
YP_933012.1	CDS	azo1508	NC_008702.1	1651391	1651927	R	Hypothetical membrane protein. No homology to the data bank. No domaine predicted. No signal peptide. 2 TMHs; hypothetical protein	complement(1651391..1651927)	Azoarcus sp. BH72	4606888
YP_933013.1	CDS	lolE1	NC_008702.1	1652224	1653480	D	Putative lipoprotein transporter permease. Homology to lolE of E. coli of 36% (sprot|LOLE_ECOLI). Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA (By similarity). Pfam: Predicted permease signal peptide 3 TMHs; High confidence in function and specificity; putative lipoprotein transporter permease	1652224..1653480	Azoarcus sp. BH72	4606889
YP_933014.1	CDS	lolD	NC_008702.1	1653473	1654180	D	Lipoprotein releasing system ATP-binding protein lolD. Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA. Similar to TREMBL:Q82VL9; TREMBL:Q8Y0C6; SWISSPROT:P75957 (58% identity). Pfam (PF00005): ABC transporter. TC (3.A.1.125): The Lipoprotein Translocase (LPT) Family.; High confidence in function and specificity; lipoprotein releasing system ATP-binding protein	1653473..1654180	Azoarcus sp. BH72	4609171
YP_933015.1	CDS	azo1511	NC_008702.1	1654177	1654722	R	Conserved hypothetical membrane protein. Homology to ne0829 of N. europaea of 46% (trembl|Q82W66(SRS)) No domains predicted No signal peptide 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1654177..1654722)	Azoarcus sp. BH72	4609170
YP_933016.1	CDS	comA	NC_008702.1	1654821	1657130	D	Competence protein comA. Essential for natural transformation. Could be a transporter involved in DNA uptake. InterPro: DNA internalization-related competence protein ComEC/Rec2 function: transporter activity TREMBL:Q82SD2: 38% identity,50% similarity. InterPro:IPR001279; Blactmase-like. IPR004477; ComEC_N-term. IPR004797; ComEC_Rec2. Pfam PF03772; Competence; 1. PF00753; Lactamase_B; 1. TIGRFAMs:TIGR00360; ComEC_N-term; 1. TIGR00361; ComEC_Rec2; ComEC_Rec2: DNA internalization-relate TMHMM predicted 8 transmembrane helices; High confidence in function and specificity; putative DNA uptake/competence protein	1654821..1657130	Azoarcus sp. BH72	4606890
YP_933017.1	CDS	azo1513	NC_008702.1	1657199	1658110	D	TREMBL:Q8XZ32: 54% identity, 66% similarity Probable Hypothetical protein Rv2715/MT2788/Mb2734. InterPro:IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 InterPro: Alpha/beta hydrolase fold Mtu_fam_11: Mycobacterium tuberculosis pa; Family membership; hydrolase	1657199..1658110	Azoarcus sp. BH72	4608510
YP_933018.1	CDS	azo1514	NC_008702.1	1658292	1659710	D	Conserved hypothetical protein. Homology to RS04633 of R.solanacearum of 73% (tremble:Q8Y0C3). Has PF04169(IPR007297);Domain of unknown function (DUF404);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). No signal Peptide or TMH present.; hypothetical protein	1658292..1659710	Azoarcus sp. BH72	4606891
YP_933019.1	CDS	azo1515	NC_008702.1	1659734	1660678	D	Conserved Hypothetical protein, 57% identity to TrEMBL;Q8Y0C2 Has PF04168;(IPR00729)Bacterial domain of unknown function (DUF403):This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF404 (IPR007297) and DUF407 (IPR007302). No Signal peptide or TMH reported Present.; Function unclear; hypothetical protein	1659734..1660678	Azoarcus sp. BH72	4606892
YP_933020.1	CDS	yjeQ	NC_008702.1	1660725	1661654	R	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase	complement(1660725..1661654)	Azoarcus sp. BH72	4606893
YP_933021.1	CDS	azo1517	NC_008702.1	1661656	1662909	R	Putative metalloprotease. Homology to ste24 of S. cerevisiae of 32% (sprot|ST24_YEAST). CAAX prenyl protease 1 (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (PPSEP 1) (A-factor converting enzyme). Proteolytically removes the C-terminal three residues of farnesylated A-factor mating pheromone. Also acts to cleave the N-terminal extension of the pheromone. probable signal peptide probable 7 TMHs; Family membership; putative metalloprotease	complement(1661656..1662909)	Azoarcus sp. BH72	4610188
YP_933022.1	CDS	orn	NC_008702.1	1663104	1663652	D	3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease	1663104..1663652	Azoarcus sp. BH72	4606894
YP_933023.1	CDS	pgi	NC_008702.1	1663676	1665385	R	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase	complement(1663676..1665385)	Azoarcus sp. BH72	4609457
YP_933024.1	CDS	azo1520	NC_008702.1	1665304	1666938	R	Conserved hypothetical membrane protein. Homology to CV1748 of C. violaceum of 32% (trembl|Q7NX80(SRS)). No domains predicted. No signal peptide 11 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1665304..1666938)	Azoarcus sp. BH72	4609530
YP_933025.1	CDS	rpmE	NC_008702.1	1667147	1667365	R	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31	complement(1667147..1667365)	Azoarcus sp. BH72	4606895
YP_933026.1	CDS	azo1522	NC_008702.1	1667410	1668510	D	putative TIM-barrel protein; Specificity unclear; hypothetical protein	1667410..1668510	Azoarcus sp. BH72	4609789
YP_933027.1	CDS	yggH	NC_008702.1	1668539	1669234	D	tRNA (guanine-N(7)-)-methyltransferase, 29% identity to SwissProt;Q8EBX8. SwissProt;Q8Y1I7(25% Identity),Q8FE22(25% identity). Has PF02390,Methyltransf_4,Putative methyltransferase;IPR003358; This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity.; tRNA (guanine-N7-)-methyltransferase	1668539..1669234	Azoarcus sp. BH72	4606896
YP_933028.1	CDS	azo1524	NC_008702.1	1669231	1669941	D	Conserved hypothetical protein. Homology to ct227 of C. tepidum of 32% (trembl|Q8KA93). Pfam: SEC-C motif This motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain. no TMHs; hypothetical protein	1669231..1669941	Azoarcus sp. BH72	4610177
YP_933029.1	CDS	azo1525	NC_008702.1	1669934	1670281	D	Conserved hypothetical protein. Homology to PA3209 of Pseudomonas aeruginosa of 43% (trembl:Q9HZ31). Has PF03692, Uncharacterised protein family (UPF0153); IPR005358;This family of proteins contain 8 conserved cysteines that may form a metal binding site. The function of these proteins is unknown but might be an Fe-S cluster as part of an oxidoreductase complex. No signal peptide. No TMHs; hypothetical protein	1669934..1670281	Azoarcus sp. BH72	4606897
YP_933030.1	CDS	azo1526	NC_008702.1	1670316	1670681	D	TREMBL:Q8XH16: 56% identity, 66% similarity. SPROT:P71300: 53% identity, 67% similarity Hypothetical protein ykgJ; This family of proteins contain 8 conserved cysteines that may form a zinc binding site. The function of these proteins is unknown InterPro:IPR005358; UPF0153. Pfam: PF03692; UPF0153 No signal peptide. No transmembrane helices; High confidence in function and specificity; ferredoxin	1670316..1670681	Azoarcus sp. BH72	4606898
YP_933031.1	CDS	azo1527	NC_008702.1	1670701	1671576	R	Function unclear; putative ATP adenylyltransferase	complement(1670701..1671576)	Azoarcus sp. BH72	4606899
YP_933032.1	CDS	azo1528	NC_008702.1	1671664	1671888	D	Conserved hypothetical protein. Homology to XAC2816 of Xanthomonas axonopodis of 52% (trembl:Q8PIS9). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1671664..1671888	Azoarcus sp. BH72	4606900
YP_933033.1	CDS	azo1529	NC_008702.1	1671902	1673644	R	42% K+channel_pore.IPR003148; TrkA_N. Pfam:PF02254; TrkA_N; 2. TMhelix:3; Function unclear; fused NAD-binding/uncharacterized domain-containing protein	complement(1671902..1673644)	Azoarcus sp. BH72	4606901
YP_933034.1	CDS	azo1530	NC_008702.1	1673655	1674038	R	Conserved hypothetical membrane protein. Homology to AQ_302 of Aquifex aeolicus of 38% (trembl|O66649). No domains predicted. No signal peptide 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1673655..1674038)	Azoarcus sp. BH72	4606902
YP_933035.1	CDS	azo1531	NC_008702.1	1674393	1675244	D	Hypothetical secreted protein. Weak homology with hits in the database. Signal Peptide present. No TMHs. No domains predicted; hypothetical protein	1674393..1675244	Azoarcus sp. BH72	4606903
YP_933036.1	CDS	azo1532	NC_008702.1	1675220	1675543	R	Hypothetical protein, 65% Identity (77% similarity) to SwissProt; Q7NS67.56% identity to SwissProt;Q8Y2R5. No domains, repeats, motifs or features present.; hypothetical protein	complement(1675220..1675543)	Azoarcus sp. BH72	4606904
YP_933037.1	CDS	acnA	NC_008702.1	1675840	1678551	R	Catalyzes the conversion of citrate to isocitrate; aconitate hydratase	complement(1675840..1678551)	Azoarcus sp. BH72	4606905
YP_933038.1	CDS	acnB	NC_008702.1	1678824	1681421	D	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	1678824..1681421	Azoarcus sp. BH72	4608263
YP_933039.1	CDS	azo1535	NC_008702.1	1681615	1684014	D	Conserved hypothetical signaling protein. Homology to ebA3785 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebA3785(KEGG)). Pfam: PF00990 GGDEF domain. PF01590 GAF domain. PF00563 EAL domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs.; Conserved hypothetical protein; putative signaling protein	1681615..1684014	Azoarcus sp. BH72	4608264
YP_933040.1	CDS	azo1536	NC_008702.1	1684130	1684609	D	Conserved hypothetical secreted protein. Homology to bd2668 of B. bacteriovorus of 53% (tremblnew|CAE80459). no domains signal peptide no TMHs; Conserved hypothetical protein; hypothetical protein	1684130..1684609	Azoarcus sp. BH72	4606906
YP_933041.1	CDS	azo1537	NC_008702.1	1684668	1685216	D	Conserved hypothetical protein. Homology to Raeut03004638 of Ralstonia eutropha of 37% (gi|45515835|ref|ZP_00167389.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	1684668..1685216	Azoarcus sp. BH72	4606907
YP_933042.1	CDS	ptsp	NC_008702.1	1685213	1686571	D	Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear; putative phosphoenolpyruvate-protein phosphotransferase	1685213..1686571	Azoarcus sp. BH72	4606908
YP_933043.1	CDS	acoA1	NC_008702.1	1686698	1687660	D	Putative acetoin dehydrogenase, alpha subunit. Homology to acoA of C. magnum of 36% (trembl|Q46142) CATALYZES THE 26-DICHLOROPHENOLINDOPHENOL-DEPENDENT CLEAVAGE OF ACETOIN INTO ACETATE AND ACETALDEHYDE IN VITRO. THE ALPHA SUBUNIT IS PROBABLY THE CATALYTIC SUBUNIT OF THE ENZYME. Pfam: Dehydrogenase E1 component no signal peptide no TMHs; Family membership; putative acetion dehydrogenase subunit alpha	1686698..1687660	Azoarcus sp. BH72	4609652
YP_933044.1	CDS	acoB1	NC_008702.1	1687671	1688627	D	Probable acetoin dehydrogenase, beta subunit. Homology to acoB of A. eutrophus of 41% (sprot|ACOB_ALCEU) Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde, in vitro. The beta subunit is probably not the catalytic subunit of the enzyme. Pfam: Transketolase, pyridine binding; Transketolase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity; acetoin dehydrogenase subunit beta	1687671..1688627	Azoarcus sp. BH72	4608265
YP_933045.1	CDS	gst	NC_008702.1	1688741	1689355	D	Putative glutathione transferase. Homology to gst of E. coli of 36% (sprot|GT_ECOLI). Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. InterPro: Glutathione S-transferase C terminus (IPR004046); Glutathione S-transferase N terminus (IPR004045) Pfam: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal no signal peptide no TMHs; High confidence in function and specificity; putative glutathione transferase	1688741..1689355	Azoarcus sp. BH72	4608267
YP_933046.1	CDS	azo1542	NC_008702.1	1689373	1690617	R	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Homolog to E. coli ynfM, an hypothetical transport protein,probably involved in antibiotic resistance. InterPro: General substrate transporters 2A0108: nitrate transporter; High confidence in function and specificity; putative membrane transport protein	complement(1689373..1690617)	Azoarcus sp. BH72	4608956
YP_933047.1	CDS	azo1543	NC_008702.1	1690740	1691627	D	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	1690740..1691627	Azoarcus sp. BH72	4606909
YP_933048.1	CDS	azo1544	NC_008702.1	1691763	1694249	D	GGDEF/EAL/PAC/PAS-domain containing protein, sym; pNGR234a) / TREMBL: trembl|Q88A61 (38% Pseudomonas syringae (pv. tomato), sensory box/ggdef domain/eal domain protein pspto0536) InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.; Conserved hypothetical protein; diguanylate cyclase	1691763..1694249	Azoarcus sp. BH72	4606910
YP_933049.1	CDS	azo1545	NC_008702.1	1694263	1695135	D	Hypotheical protein. No good homology of the entire protein with the data base. No domains predicted. No THs. No signal peptide.; hypothetical protein	1694263..1695135	Azoarcus sp. BH72	4606911
YP_933050.1	CDS	citE	NC_008702.1	1695143	1696138	R	Probable Citrate lyase beta chain(EC 4.1.3.6)(Citrase)(Citryl-CoA lyase subunit)(EC 4.1.3.34). In citrate-utilising prokaryotes, citrate lyase cleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha,beta, and gamma subunits.The alpha subunit substitutes citryl for the acetyl group to form citryl-S-ACP. The beta subunit completes the reaction by cleaving the citryl to yield oxaloacetate and (regenerated) acetyl-S-ACP. Similar to the CitE protein from L.mesenteroides where is part of a gene cluster citCDEFG. SWISSPROT:CILB_LEUMC.O53078. InterPro:IPR006475; CitE.IPR001465; Malate_synthase. TIGRFAMs:TIGR01588; citE; 1.; Function unclear; putative citrate lyase subunit beta	complement(1695143..1696138)	Azoarcus sp. BH72	4606912
YP_933051.1	CDS	mdh	NC_008702.1	1696246	1697238	R	catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase	complement(1696246..1697238)	Azoarcus sp. BH72	4608485
YP_933052.1	CDS	frlR	NC_008702.1	1697454	1698182	D	Putative GntR-family transcriptional regulator,; Family membership; GntR family transcriptional regulator	1697454..1698182	Azoarcus sp. BH72	4609206
YP_933053.1	CDS	sdhC	NC_008702.1	1698280	1698669	D	Succinate dehydrogenase cytochrome b-556 subunit,sdhC.58% Identity to TrEMBL;Q7NZ57.52% to TrEMBL;Q9JRJ0,36% to SwissProt;P10446. Has PF01127,Succinate dehydrogenase cytochrome b subunit;IPR000701 Sdh_cyt; Succinate dehydrogenase (SDH) is a membrane-bound complex of two main components: a membrane-extrinsic component composed of an FAD-binding flavoprotein and an iron-sulphur protein, and a hydrophobic component composed of a cytochrome b and a membrane anchor protein.The cytochrome b component is a mono heme transmembrane protein belonging to a family that includes cytochrome b-556 from bacterial SDH (gene sdhC); cytochrome b560 from the mammalian mitochondrial SDH complex and that encoded in the mitochondrial genome of some algae and in the plant Marchantia polymorpha; cytochrome b from yeast mitochondrial SDH complex (gene SDH3 or CYB3); and protein cyt-1 from Caenorhabditis. These cytochromes are proteins of about 130 residues that comprise three transmembrane regions. There are two conserved histidines which may be involved in binding the heme group.; succinate dehydrogenase	1698280..1698669	Azoarcus sp. BH72	4608829
YP_933054.1	CDS	sdhD	NC_008702.1	1698666	1699010	D	Succinate dehydrogenase, hydrophobic membrane anchor subunit. Homology to sdhD of C. burnetii of 41% (sprot|DHSD_COXBU). THIS IS THE HYDROPHOBIC COMPONENT OF THE SUCCINATE DEHYDROGENASE COMPLEX. IT IS SUGGESTED THAT IT IS REQUIRED TO ANCHOR THE CATALYTIC COMPONENTS TO THE CYTOPLASMIC MEMBRANE. no signal peptide 3 TMHS; Family membership; succinate dehydrogenase, hydrophobic membrane anchor subunit	1698666..1699010	Azoarcus sp. BH72	4609855
YP_933055.1	CDS	sdhA	NC_008702.1	1699013	1700806	D	Probable succinate dehydrogenase, flavoprotein subunit. Homology to sdhA of C. burnetii of 54% (sprot|DHSA_COXBU) Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein,cytochrome b-556 and a hydrophobic protein. CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced acceptor. InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal (IPR003953); Fumarate reductase/succinate dehydrogenase FAD-binding site (IPR003952); Fumarate reductase/succinate dehydrogenase, C-terminal (IPR004112) Pfam: FAD-binding domain; Fumarate reductase/succinate dehydrogenase no TMHs no signal peptide gidA: glucose-inhibited division prot; High confidence in function and specificity; succinate dehydrogenase, flavoprotein subunit	1699013..1700806	Azoarcus sp. BH72	4609856
YP_933056.1	CDS	sdhB	NC_008702.1	1700826	1701536	D	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit	1700826..1701536	Azoarcus sp. BH72	4609853
YP_933057.1	CDS	azo1553	NC_008702.1	1701539	1701775	D	Conserved hypothetical protein, 39% identity to Swissprot;Q46825, ygfY of Escherichia coli. Has PF03937:(IPR005631, DUF339)TPR repeat region;This family represents a set of three divergent TPR repeats found in a small group of uncharacterised proteins. No Signal Peptide or TMH present.; Family membership; hypothetical protein	1701539..1701775	Azoarcus sp. BH72	4609854
YP_933058.1	CDS	gltA	NC_008702.1	1701845	1703140	D	Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity; citrate synthase	1701845..1703140	Azoarcus sp. BH72	4606913
YP_933059.1	CDS	sucA	NC_008702.1	1703300	1706131	D	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component	1703300..1706131	Azoarcus sp. BH72	4608914
YP_933060.1	CDS	odhB	NC_008702.1	1706183	1707385	D	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase	1706183..1707385	Azoarcus sp. BH72	4609436
YP_933061.1	CDS	odhL	NC_008702.1	1707467	1708891	D	E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase	1707467..1708891	Azoarcus sp. BH72	4609437
YP_933062.1	CDS	azo1558	NC_008702.1	1708972	1711326	R	conserved hypothetical protein but a part of protein have similarity to potassium-transporting ATPase,A subunit. TIGR Cellular role(s):Transport and binding proteins: Cations Entry name :- SWISSPROT:YACK_RHIME Prim. accession # Q9X447 Identity:-46% interPro :-IPR004623; K_ATPaseA. Pfam PF03814; KdpA; 1. Number of predicted TMHs: 0 Signal peptide probability: 0.082; hypothetical protein	complement(1708972..1711326)	Azoarcus sp. BH72	4609438
YP_933063.1	CDS	afg	NC_008702.1	1711473	1712678	D	Hypothetical protein yhcM. TREMBL:Q8XZX3: 54% identity, 69% similarity This family of proteins contains a P-loop motif and are predicted to be ATPases InterPro:IPR005654; AFG1_ATPase. Pfam PF03969; AFG1_ATPase No signal peptide No transmembrane helices L9: ribosomal protein L9; Specificity unclear; ATPase	1711473..1712678	Azoarcus sp. BH72	4606914
YP_933064.1	CDS	yoaA	NC_008702.1	1712686	1714659	D	Probable ATP-dependent helicase,; Family membership; ATP-dependent helicase	1712686..1714659	Azoarcus sp. BH72	4608284
YP_933065.1	CDS	mobB1	NC_008702.1	1714770	1715264	D	Molybdopterin-guanine dinucleotide biosynthesis protein B. may bind the guanine nucleotide required for the synthesis of molybdopterin guanine dinucleotide. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity; molybdopterin-guanine dinucleotide biosynthesis protein B	1714770..1715264	Azoarcus sp. BH72	4610194
YP_933066.1	CDS	moeA1	NC_008702.1	1715261	1716466	D	Molybdopterin biosynthesis protein moeA. Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin) necessary for molybdo-enzymes. Seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum. InterPro: Molybdenum cofactor biosynthesis protein molyb_syn: molybdenum cofactor synthesis; High confidence in function and specificity; molybdopterin cofactor biosynthesis protein	1715261..1716466	Azoarcus sp. BH72	4609246
YP_933067.1	CDS	moaD	NC_008702.1	1716479	1716733	D	Molybdopterin converting factor subunit 1 (MPT synthase subunit 1) (Molybdopterin synthase subunit 1) (Molybdenum cofactor biosynthesis protein D) . Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur atoms are provided by the active form of the small subunit whose activation involves the acquisition of sulfur and the activity of moeB/chlN.; High confidence in function and specificity; molybdopterin converting factor subunit	1716479..1716733	Azoarcus sp. BH72	4609257
YP_933068.1	CDS	moaE	NC_008702.1	1716738	1717208	D	Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2) . Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.; High confidence in function and specificity; molybdenum cofactor biosynthesis protein E	1716738..1717208	Azoarcus sp. BH72	4609243
YP_933069.1	CDS	phaP	NC_008702.1	1717276	1717779	R	Putative phasin protein PhaP.A family of small proteins found associated with inclusions in bacterial cells. Most associate with polyhydroxyalkanoate (PHA) inclusions, the most common of which consist of polyhydroxybutyrate (PHB). These are designated granule-associate proteins or phasins. However, the member from Magnetospirillum sp. AMB-1 is called a magnetic particle membrane-specific GTPase. TrEMBL: Q93QF2 InterPro:IPR010127,TIGR01841 NO TMH Present No Signal Peptide Present; Family membership; putative phasin protein	complement(1717276..1717779)	Azoarcus sp. BH72	4609244
YP_933070.1	CDS	clpB1	NC_008702.1	1718010	1720592	D	Probable ATP-dependent Clp protease, ATP-binding subunit ClpB. Homology to clpB of E. coli of 66% (sprot|CLPB_ECOLI). The protein is thought to be subunits of ATP-dependent proteases which act as chaperones to target the proteases to substrates. Pfam: ATPase family assocciated with various cellular activities; CPL amino terminal domain no signal peptide no TMHs; High confidence in function and specificity; ATP-dependent Clp protease ATP-binding subunit ClpB	1718010..1720592	Azoarcus sp. BH72	4609537
YP_933071.1	CDS	azo1567	NC_008702.1	1720639	1723911	R	GGDEF/EAL-domain containing protein; diguanylate cyclase	complement(1720639..1723911)	Azoarcus sp. BH72	4608487
YP_933072.1	CDS	ppiD	NC_008702.1	1724061	1725956	D	Putative peptidyl-prolyl cis-trans isomerase. Homology to ppiD of E. coli of 23% (sprot|PPID_ECOLI). PPIASES ACCELERATE THE FOLDING OF PROTEINS. SEEMS TO BE INVOLVED IN THE FOLDING OF OUTER MEMBRANE PROTEINS. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain probable 1 TMH no signal peptide; Family membership; putative peptidyl-prolyl cis-trans isomerase	1724061..1725956	Azoarcus sp. BH72	4606915
YP_933073.1	CDS	fabI1	NC_008702.1	1726037	1726828	R	CATALYTIC ACTIVITY: Acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH Entry name:- SWISSPROT:FABI_PSEAE Prim. accession # Q9ZFE4 Identities = 173/260 (66%) InterPro :- IPR002198; ADH_short. Pfam:- PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.044 Number of predicted TMHs: 0; High confidence in function and specificity; enoyl-acyl carrier protein reductase	complement(1726037..1726828)	Azoarcus sp. BH72	4609611
YP_933074.1	CDS	azo1570	NC_008702.1	1726995	1727903	D	Conserved hypothetical membrane protein. Homology to RSC3414 of Ralstonia solanacearum of 48% (sprot|YY14_RALSO(SRS)), Has PF05249:(IPR007913);Uncharacterised protein family (UPF0187);This family of proteins is functionally uncharacterised. signal peptide 2 TMHs; Conserved hypothetical protein; hypothetical protein	1726995..1727903	Azoarcus sp. BH72	4608714
YP_933075.1	CDS	azo1571	NC_008702.1	1727944	1730145	D	Conserved hypothetical protein. Homology to hbpA of N. europaea of 56%. Protein consist of two domains: 1. bacterial extracellular sloute protein with homology to heme-binding protein A which is important for the heme aquisition and 2. a transmembrane helix a the C-terminus (unusual combination). Interpro: Bacterial extracellular solute-binding protein, family 5 (IPR000914) Pfam: Bacterial extracellular solute binding protein Signal peptide one TMH; hypothetical protein	1727944..1730145	Azoarcus sp. BH72	4606916
YP_933076.1	CDS	appB	NC_008702.1	1730147	1731124	D	Dipeptide transport system permease dppB. Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component crcB: crcB protein; High confidence in function and specificity; putative oligopeptide ABC transporter permease	1730147..1731124	Azoarcus sp. BH72	4606917
YP_933077.1	CDS	appC	NC_008702.1	1731121	1732533	D	Oligopeptide transport system permease appC. This protein is a component of an oligopeptide permease a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence though unlike OPP is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity). pts-Glc: PTS system maltose and gluco; High confidence in function and specificity; oligopeptide ABC transporter permease	1731121..1732533	Azoarcus sp. BH72	4608328
YP_933078.1	CDS	azo1574	NC_008702.1	1732640	1734199	D	Conserved hypothetical protein. Homology to XCC2284 of X.campestris of 67% (tremble:Q8P8F8) Has PF02696;Uncharacterized ACR, YdiU/UPF0061 family(Protein of Unknown Function), IPR003846. No signal peptide. No TMHs; hypothetical protein	1732640..1734199	Azoarcus sp. BH72	4608329
YP_933079.1	CDS	nnrU	NC_008702.1	1734206	1734787	R	Probable NnrU protein, 31% identity to TrEMBL;Q92Z13, Q9AAA0 Has PF07298(IPR009915):NnrU protein;This family consists of several plant and bacterial NnrU proteins. NnrU is thought to be involved in the reduction of nitric oxide. The exact function of NnrU is unclear. It is thought however that NnrU and perhaps NnrT are required for expression of both nirK and nor; NnrU family protein	complement(1734206..1734787)	Azoarcus sp. BH72	4606918
YP_933080.1	CDS	smpB	NC_008702.1	1734888	1735334	R	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein	complement(1734888..1735334)	Azoarcus sp. BH72	4609388
YP_933081.1	CDS	azo1577	NC_008702.1	1735447	1735884	D	Entry name TREMBL:Q8XZH0 Prim. accession # Q8XZH0 InterPro :- IPR005340; UPF0083. Pfam PF03654; ARPF; 1. Identities = 78/142 (54%), Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; hypothetical protein	1735447..1735884	Azoarcus sp. BH72	4609877
YP_933082.1	CDS	azo1578	NC_008702.1	1735881	1736204	D	Conserved hypothetical protein. Homology to CV3462 of C.violaceum of 54% (tremble:Q7NSG4) Has PF03658;Uncharacterised protein family (UPF0125). IPR005346 Has no signal peptide or TMH present.; hypothetical protein	1735881..1736204	Azoarcus sp. BH72	4606919
YP_933083.1	CDS	azo1579	NC_008702.1	1736223	1736780	R	Conserved hypothetical secreted protein. Homology to RS05265 of R. solanacearum of 30% (trembl|Q8XZG8(SRS)) No domains predicted Signal peptide present No TMH reported.; Conserved hypothetical protein; hypothetical protein	complement(1736223..1736780)	Azoarcus sp. BH72	4606920
YP_933084.1	CDS	guaB	NC_008702.1	1736897	1738357	D	IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase) (Inosinic acid dehydrogenase) (Inosinate dehydrogenase) (IMP oxidoreductase) (Inosine monophosphate oxidoreductase) kpsF: KpsF/GutQ family protein; High confidence in function and specificity; IMP dehydrogenase	1736897..1738357	Azoarcus sp. BH72	4606921
YP_933085.1	CDS	guaA	NC_008702.1	1738436	1740001	D	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase	1738436..1740001	Azoarcus sp. BH72	4608962
YP_933086.1	CDS	azo1582	NC_008702.1	1740086	1740970	R	HTH-type transcriptional activator,; Specificity unclear; HTH-type transcriptional activator	complement(1740086..1740970)	Azoarcus sp. BH72	4608961
YP_933087.1	CDS	nqo1	NC_008702.1	1741067	1741870	D	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase). The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis (By similarity). trembl:Q9I4B4:72%identity; 81% similarity InterPro: NAD(P)H dehydrogenase (quinone) InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 crcB: crcB protein No signal peptide present Absence of transmembrane helices (TMHMM predicted); High confidence in function and specificity; NAD(P)H dehydrogenase, quinone 1	1741067..1741870	Azoarcus sp. BH72	4606922
YP_933088.1	CDS	azo1584	NC_008702.1	1741890	1743509	R	Putative two-component hybrid sensor and regulator ,; Function unclear; putative two-component hybrid sensor and regulator	complement(1741890..1743509)	Azoarcus sp. BH72	4609410
YP_933089.1	CDS	azo1585	NC_008702.1	1743693	1744202	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 1 TMH; hypothetical protein	complement(1743693..1744202)	Azoarcus sp. BH72	4606923
YP_933090.1	CDS	azo1586	NC_008702.1	1744406	1744909	R	Conserved hypothetical secreted protein. Homology to Avin02003713 of Azotobacter vinelandii of 35% (gi|53610668|ref|ZP_00089587.2|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(1744406..1744909)	Azoarcus sp. BH72	4606924
YP_933091.1	CDS	azo1587	NC_008702.1	1744963	1746744	R	Putative two-component system sensor protein,; Function unclear; putative two-component system sensor protein	complement(1744963..1746744)	Azoarcus sp. BH72	4606925
YP_933092.1	CDS	cumB	NC_008702.1	1746847	1747311	D	Cytidine deaminase (EC: 3.5.4.5) (cytidine aminohydrolase) catalyzes the hydrolysis of cytidine into uridine and ammonia while deoxycytidylate deaminase (EC: 3.5.4.12) (dCMP deaminase) hydrolyzes dCMP into dUMP. Both enzymes are known to bind zinc and to require it for their catalytic activity [1, 2]. These two enzymes do not share any sequence similarity with the exception of a region that contains three conserved histidine and cysteine residues which are thought to be involved in the binding of the catalytic zinc ion.; High confidence in function and specificity; cytidine deaminase	1746847..1747311	Azoarcus sp. BH72	4606926
YP_933093.1	CDS	azo1589	NC_008702.1	1747313	1747792	D	Conserved hypothetical protein. Homology to CBU1080 of C.burnetii of 59% (tremble:Q83CN1) Has PF03734;ErfK/YbiS/YcfS/YnhG;(IPR005490)This family of proteins are found in a range of bacteria. Th conserved region contains a conserved histidine and cysteine,suggesting that these proteins have an enzymatic activity. Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate. No TMHs. No signal peptide.; hypothetical protein	1747313..1747792	Azoarcus sp. BH72	4608542
YP_933094.1	CDS	azo1590	NC_008702.1	1747789	1748220	D	Conserved hypothetical acetyltransferase. Homology to glr3404 of G. violaceus of 52% (trembl|Q7NFX1). InterPro: GCN5-related N-acetyltransferase (IPR000182) Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHS; Family membership; acetyltransferase	1747789..1748220	Azoarcus sp. BH72	4606927
YP_933095.1	CDS	azo1591	NC_008702.1	1748232	1748999	R	Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present.; hypothetical protein	complement(1748232..1748999)	Azoarcus sp. BH72	4606928
YP_933096.1	CDS	azo1592	NC_008702.1	1748990	1749307	R	Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1748990..1749307)	Azoarcus sp. BH72	4606929
YP_933097.1	CDS	azo1593	NC_008702.1	1749321	1750349	R	Conserved hypothetical protein aminomethyltransferase . Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein; Specificity unclear; aminomethyltransferase	complement(1749321..1750349)	Azoarcus sp. BH72	4606930
YP_933098.1	CDS	azo1594	NC_008702.1	1750580	1751584	D	Hypothetical protein HI0457. This entry describes proteins of unknown function TREMBL:Q8XYH5: 50% identity,66% similarity InterPro:IPR003770; DUF175. Pfam:PF02618; ADC_lyas Non secretory protein with signal peptide probability 0.977 (Signal P predicted) No. of transmembrane helices: 1 (TMHMM predicted) This entry describes proteins of unknown function 2A0108: nitrate transporter; Function unclear; hypothetical protein	1750580..1751584	Azoarcus sp. BH72	4606931
YP_933099.1	CDS	tmk	NC_008702.1	1751590	1752210	D	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase	1751590..1752210	Azoarcus sp. BH72	4606932
YP_933100.1	CDS	holB	NC_008702.1	1752207	1753256	D	DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime.; High confidence in function and specificity; DNA-directed DNA polymerase	1752207..1753256	Azoarcus sp. BH72	4609953
YP_933101.1	CDS	pilZ	NC_008702.1	1753253	1753624	D	Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875 ;This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown.; type IV pilus assembly protein PilZ	1753253..1753624	Azoarcus sp. BH72	4609013
YP_933102.1	CDS	azo1598	NC_008702.1	1753650	1754420	D	Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family.; Specificity unclear; putative deoxyribonuclease	1753650..1754420	Azoarcus sp. BH72	4609581
YP_933103.1	CDS	ank1	NC_008702.1	1754407	1755096	D	Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro: Ankyrin-repeat Pfam:Phage_integr_N:Phage integrase, N-terminal SAM-like wecB_tagA_cpsF: glycosyl transferase. Transmembrane helices 0 and presence of signal peptide (Signal P)for exporting.(probably signal peptide bearing exported protein); Specificity unclear; ankyrin repeat-containing protein	1754407..1755096	Azoarcus sp. BH72	4606933
YP_933104.1	CDS	azo1600	NC_008702.1	1755103	1755936	R	Conserved hypothetical protein. Homology to Rgel02003216 of Rubrivivax gelatinosus of 54% (gi|47572589|ref|ZP_00242632.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(1755103..1755936)	Azoarcus sp. BH72	4608320
YP_933105.1	CDS	azo1601	NC_008702.1	1755933	1756850	R	Histone deacetylases catalyse the removal of the acetyl group from histones. Histone deacetylase, acetoin utilization proteins and acetylpolyamine amidohydrolases are all members of an ancient family, TREMBL:Q7NVL6 (58% identity); TREMBL:Q8XZ00 (57% identity). InterPro (IPR000286): Histone deacetylase superfamily Pfam (PF00850): Histone deacetylase domain.; Family membership; histone deacetylase family protein	complement(1755933..1756850)	Azoarcus sp. BH72	4606934
YP_933106.1	CDS	azo1602	NC_008702.1	1756888	1757868	R	Conserved hypothetical protein. Homology to Rv2569c/MT2645/Mb2599c of M. bovis of 38%. Pfam: Transglutaminase-like superfamily. no signal peptide no TMHs; Specificity unclear; hypothetical protein	complement(1756888..1757868)	Azoarcus sp. BH72	4606935
YP_933107.1	CDS	azo1603	NC_008702.1	1757930	1760416	R	Conserved hypothetical protein,52% Identity to TrEMBL;Q9HUN7. Has PF04169;Domain of unknown function (DUF404);(IPR007297)This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). Has PF04168;Bacterial domain of unknown function (DUF403);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF404 (IPR007297) and DUF407 (IPR007302).; Specificity unclear; hypothetical protein	complement(1757930..1760416)	Azoarcus sp. BH72	4606936
YP_933108.1	CDS	azo1604	NC_008702.1	1760466	1763846	R	Transglutaminase-like superfamily domain protein;67% identity (79% similarity) to TrEMBL;Q87VL0. TrEMBL;Q6N3E0(57% identity). Has SMART;SM00460,TGc;Transglutaminase/protease-like homologues: (IPR002931):Transglutaminases are enzymes that establish covalent links between proteins. A subset of transglutaminase homologues appear to catalyse the reverse reaction, the hydrolysis of peptide bonds. Proteins with this domain are both extracellular and intracellular, and it is likely that the eukaryotic intracellular proteins are involved in signalling events. NO signal peptide or TMH present.; High confidence in function and specificity; hypothetical protein	complement(1760466..1763846)	Azoarcus sp. BH72	4606937
YP_933109.1	CDS	hipO2	NC_008702.1	1764095	1765264	D	Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7WFU4: 48% identity, 58% similarity InterPro:IPR002933; Peptidase_M20. IPR010168; Pept_M20D_amidh. Pfam: PF01546; Peptidase_M20; 1. TIGRFAMs TIGR01891; amidohydrolases No signal peptide present No transmembrane helices present mreB: cell shape determining protein M; High confidence in function and specificity; hippurate hydrolase	1764095..1765264	Azoarcus sp. BH72	4606938
YP_933110.1	CDS	azo1606	NC_008702.1	1765274	1767766	D	Similar to TREMBL:Q7WGZ1 (41% identity); TREMBL:Q7W9R7 (41% identity); TREMBL:Q8XXM2 (37% identity). Pfam (DUF214): Predicted permease. TMHMM reporting 10 transmembrane helices.; Specificity unclear; putative inner membrane transport permease	1765274..1767766	Azoarcus sp. BH72	4608998
YP_933111.1	CDS	moaA	NC_008702.1	1767782	1768855	R	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A	complement(1767782..1768855)	Azoarcus sp. BH72	4606939
YP_933112.1	CDS	azo1608	NC_008702.1	1769067	1769345	D	hypothetical protein having 55% similarity with Nitrosomonas europaea No Signal peptide present No TMH reported.; hypothetical protein	1769067..1769345	Azoarcus sp. BH72	4609241
YP_933113.1	CDS	azo1609	NC_008702.1	1769477	1771894	D	Conserved hypothetical ATP-dependent protease. Homology to gsu2433 of G. sulfurreducens of 40% (tremblnew|AAR35806). Tigrfam:lon_rel: ATP-dependent protease puta no signal peptide no TMHs; High confidence in function and specificity; ATP-dependent protease	1769477..1771894	Azoarcus sp. BH72	4606940
YP_933114.1	CDS	tyrB	NC_008702.1	1772287	1773495	R	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase	complement(1772287..1773495)	Azoarcus sp. BH72	4609986
YP_933115.1	CDS	uvrB	NC_008702.1	1773639	1775714	D	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B	1773639..1775714	Azoarcus sp. BH72	4610055
YP_933116.1	CDS	ptpA	NC_008702.1	1775724	1776188	D	Low molecular weight protein-tyrosine-phosphatase,; High confidence in function and specificity; PtpA protein	1775724..1776188	Azoarcus sp. BH72	4610082
YP_933117.1	CDS	rne	NC_008702.1	1776283	1779327	R	Probable ribonuclease E (EC 3.1.4.-) (RNase E). Homology to rne of E. coli of 44% (sprot|RNE_ECOLI) This protein matures 5S rRNA from its precursors from all the rRNA genes. It is the major endoribonuclease participating in mRNA turnover. Interpro: Ribonuclease E and G (IPR004659); S1 RNA binding domain (IPR003029) Pfam: S1 RNA binding domain Tigrfam: RNase EG: ribonuclease,Rne/Rng family no signal peptide no TMHs; Family membership; ribonuclease E	complement(1776283..1779327)	Azoarcus sp. BH72	4609647
YP_933118.1	CDS	rluC	NC_008702.1	1779739	1780698	D	Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil at positions 955 2504 and 2580 in 23S ribosomal RNA.; Family membership; ribosomal large subunit pseudouridine synthase C	1779739..1780698	Azoarcus sp. BH72	4609739
YP_933119.1	CDS	azo1615	NC_008702.1	1780691	1781347	D	TREMBL:Q7VSFO: Probable hydrolase, 55% identity,63% similarity Phosphoglycolate phosphatase (PGP). InterPro:PR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Haloacid dehaloginase like hydrolase TIGRFAMs:TIGR01549; HAD-SF-IA-v1; TIGR01509; HAD-SF-IA-v3; serB: phosphoserine phosphatase SerB hstdl_phs_rel: histidinol phosphatase-; Function unclear; hydrolase	1780691..1781347	Azoarcus sp. BH72	4609733
YP_933120.1	CDS	azo1616	NC_008702.1	1781326	1781682	D	Conserved hypothetical ferredoxin subunits of nitrite reductase. Conserved Rieske domain is present. Similar to NirD from E.Coli. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit Non-secretory protein; Function unclear; ferredoxin protein	1781326..1781682	Azoarcus sp. BH72	4606942
YP_933121.1	CDS	azo1617	NC_008702.1	1781715	1782626	D	Conserved hypothetical peptidase. Haomology to ne1024 of N. europaea of 59% (trembl|Q82VP2) InterPro: Peptidase family U7 (IPR002142) Tigrfam: SppA_dom: signal peptide peptidase SppA Pfam: Peptidase family U7 no signal peptide probable 1 TMH; High confidence in function and specificity; peptidase	1781715..1782626	Azoarcus sp. BH72	4606943
YP_933122.1	CDS	azo1618	NC_008702.1	1782623	1783348	R	Conserved hypothetical protein. Homology to bpp3312 of B. parapertussis (trembl|Q7WD15). TIGR00096: conserved hypothetical protein Pfam: Tetrapyrrole (Corrin/Porphyrin) Methyltransferase no signal peptide no TMHs; hypothetical protein	complement(1782623..1783348)	Azoarcus sp. BH72	4606944
YP_933123.1	CDS	yceF	NC_008702.1	1783345	1783923	R	Maf-like protein yceF. InterPro: Maf-like protein; Family membership; Maf-like protein	complement(1783345..1783923)	Azoarcus sp. BH72	4606945
YP_933124.1	CDS	azo1620	NC_008702.1	1784046	1784531	D	Conserved hypothetical protein. Homology to CV3419 of Chromobacterium violaceum of 42% (trembl:Q7NSK4). Has PF02620, Uncharacterized ACR,IPR003772;This entry describes proteins of unknown function. No signal peptide. No TMHs; hypothetical protein	1784046..1784531	Azoarcus sp. BH72	4610156
YP_933125.1	CDS	rpmF	NC_008702.1	1784569	1784748	D	some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32	1784569..1784748	Azoarcus sp. BH72	4606946
YP_933126.1	CDS	plsX	NC_008702.1	1784837	1785853	D	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX	1784837..1785853	Azoarcus sp. BH72	4609790
YP_933127.1	CDS	fabH	NC_008702.1	1785850	1786815	D	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase	1785850..1786815	Azoarcus sp. BH72	4609585
YP_933128.1	CDS	fabD	NC_008702.1	1786843	1787772	D	Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity; malonyl CoA-acyl carrier protein transacylase	1786843..1787772	Azoarcus sp. BH72	4608713
YP_933129.1	CDS	fabG	NC_008702.1	1787775	1788524	D	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase	1787775..1788524	Azoarcus sp. BH72	4608708
YP_933130.1	CDS	acpP	NC_008702.1	1788618	1788857	D	carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein	1788618..1788857	Azoarcus sp. BH72	4608711
YP_933131.1	CDS	fabF1	NC_008702.1	1788940	1790175	D	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II	1788940..1790175	Azoarcus sp. BH72	4608270
YP_933132.1	CDS	azo1628	NC_008702.1	1790198	1790665	D	Conserved hypothetical membrane protein. Homology to ebA5460 of Azoarcus sp. EbN1 of 32% (gnl|keqq|eba:ebA5460(KEGG)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	1790198..1790665	Azoarcus sp. BH72	4608709
YP_933133.1	CDS	nadB	NC_008702.1	1790655	1792244	R	catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase	complement(1790655..1792244)	Azoarcus sp. BH72	4606947
YP_933134.1	CDS	algU	NC_008702.1	1792464	1793063	D	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE	1792464..1793063	Azoarcus sp. BH72	4609303
YP_933135.1	CDS	rseA	NC_008702.1	1793073	1793618	D	Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity; putative sigma-E factor, negative regulatory protein	1793073..1793618	Azoarcus sp. BH72	4608299
YP_933136.1	CDS	rseB	NC_008702.1	1793615	1794586	D	Putative sigma factor regulatory protein,; High confidence in function and specificity; putative sigma factor regulatory protein	1793615..1794586	Azoarcus sp. BH72	4609825
YP_933137.1	CDS	rseC	NC_008702.1	1794586	1795026	D	Putative sigma-E factor regulatory protein RseC,; High confidence in function and specificity; putative sigma-E factor regulatory protein RseC	1794586..1795026	Azoarcus sp. BH72	4609826
YP_933138.1	CDS	mucD2	NC_008702.1	1795023	1796441	D	Probable serine protease MucD. Homology to mucD of P. aruginosa of 47% (trembl|Q57155) InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (also known as DHR or GLGF) (IPR001478); Chymotrypsin serin protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs ahpD_dom: alkylhydroperoxidase AhpD fam; High confidence in function and specificity; serine protease MucD	1795023..1796441	Azoarcus sp. BH72	4609827
YP_933139.1	CDS	azo1635	NC_008702.1	1796438	1796695	D	Conserved hypothetical thioredoxin. Homology to a putative thioredoxin of N. menigitidis (NMA0966) of 50%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. no signal peptide no TMHs; Function unclear; thioredoxin-disulfide reductase	1796438..1796695	Azoarcus sp. BH72	4609284
YP_933140.1	CDS	azo1636	NC_008702.1	1796728	1797744	R	HTH-type transcriptional regulator,; Family membership; HTH-type transcriptional regulator	complement(1796728..1797744)	Azoarcus sp. BH72	4606948
YP_933141.1	CDS	azo1637	NC_008702.1	1797863	1798198	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide 3 TMHs; hypothetical protein	1797863..1798198	Azoarcus sp. BH72	4606949
YP_933142.1	CDS	azo1638	NC_008702.1	1798230	1799195	D	Putative exported protein, 39% identity (54% similarity)to TrEMBL;Q7VUI5 TrEMBL;Q7WNJ8. Has PF03401;Bordetella uptake gene (bug) product;(IPR005064)These probable extra-cytoplasmic solute receptors are strongly overrepresented in several beta-proteobacteria. SIgnal Peptide Present. No TMH reported present.; Specificity unclear; hypothetical protein	1798230..1799195	Azoarcus sp. BH72	4606950
YP_933143.1	CDS	lepA	NC_008702.1	1799548	1801344	D	binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA	1799548..1801344	Azoarcus sp. BH72	4606951
YP_933144.1	CDS	lepB	NC_008702.1	1801366	1802154	D	Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I). SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one or two N-terminal transmembrane domains, with the main part of the protein protuding in the periplasmic space. SPase I can cleave N-terminal leader sequences of nonlipoprotein that are exported by the SecYEG pathway or the twin arginine translocation (Tat) pathway. Pfam: Peptidase_S26 probable 2 TMH no signal peptide; High confidence in function and specificity; LepB protein	1801366..1802154	Azoarcus sp. BH72	4609127
YP_933145.1	CDS	azo1641	NC_008702.1	1802170	1802529	D	Conserved hypothetical secreted protein. Homology with NE2325 of N.europaea of 41% (tremble:Q82SJ5) No domains predicted. Signal peptide Present. No TMH reported.; Conserved hypothetical protein; hypothetical protein	1802170..1802529	Azoarcus sp. BH72	4609128
YP_933146.1	CDS	rnc	NC_008702.1	1802535	1803206	D	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III	1802535..1803206	Azoarcus sp. BH72	4606952
YP_933147.1	CDS	era	NC_008702.1	1803203	1804117	D	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era	1803203..1804117	Azoarcus sp. BH72	4609738
YP_933148.1	CDS	recO	NC_008702.1	1804142	1804873	D	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO	1804142..1804873	Azoarcus sp. BH72	4608674
YP_933149.1	CDS	pdxJ	NC_008702.1	1804870	1805619	D	involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase	1804870..1805619	Azoarcus sp. BH72	4609709
YP_933150.1	CDS	acpS	NC_008702.1	1805634	1806011	D	Holo-[acyl-carrier-protein] synthase, 50% Identity to TrEMBL;Q7NWB8, Q820I1. SProt;Q9KPB6(49%). Has PF01648,4'-phosphopantetheinyl transferase superfamily; IPR008278 4-PPT_transf; Members of this family transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to the invariant serine of PP-binding. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP. This superfamily consists of two subtypes: The ACPS type such as P24224 and the Sfp type such as P39135. The structure of the Sfp type is known which shows the active site accommodates a magnesium ion. The most highly conserved regions of the alignment are involved in binding the magnesium ion.; holo-[acyl-carrier-protein] synthase	1805634..1806011	Azoarcus sp. BH72	4609517
YP_933151.1	CDS	nagZ2	NC_008702.1	1806008	1807141	D	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase	1806008..1807141	Azoarcus sp. BH72	4608271
YP_933152.1	CDS	uvrC	NC_008702.1	1807351	1809171	D	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C	1807351..1809171	Azoarcus sp. BH72	4609316
YP_933153.1	CDS	pgsA	NC_008702.1	1809267	1809839	D	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGP synthase). It catalyses the conversion of CDP-diacylglycerol and glycerol-3-phosphate to CMP and 3-(3-phosphatidyl)-glycerol 1-phosphate in the commited step to the synthesis of acidic phospholipids. It is an integral membrane protein. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. Entry name :-SWISSPROT:PGSA_ECOLI Prim. accession # P06978 Identities = 50% InterPro IPR000462; CDP-OH_P_trans. IPR004570; PgsA. Pfam PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 5 Prediction: Non-secretory protein Signal peptide probability: 0.109; Family membership; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	1809267..1809839	Azoarcus sp. BH72	4610083
YP_933154.1	CDS	azo1650	NC_008702.1	1810266	1811441	D	Probable Serine--pyruvate aminotransferase mitochondrial precursor (EC 2.6.1.51) (SPT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44) (AGT). TREMBL:Q7P1E0:36% identity, 45% similarity This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase I / nucleotide pyrophosphatase (nppase). These enzymes catalyse the cleavage of phosphodiester and phosphosulphate bonds in NAD, deoxynucleotides and nucleotide sugars InterPro:IPR002591; Phosphodiest. Pfam:PF01663; Phosphodiest; bcpB: phosphonopyruvate decarboxylase-rel No transmembrane helices; Function unclear; putative phosphodiesterase	1810266..1811441	Azoarcus sp. BH72	4609994
YP_933155.1	CDS	azo1651	NC_008702.1	1811528	1811716	D	Hypothetical protein. No homologs in the database. Has No domains, repeats, motifs or features.; hypothetical protein	1811528..1811716	Azoarcus sp. BH72	4606953
YP_933156.1	CDS	azo1652	NC_008702.1	1811729	1812199	R	Conserved hypothetical protein. Homology to RS03611 of R.solanacearum of 40% (trembl:Q8XXR7). Has PF06676(IPR009562):Protein of unknown function (DUF1178);This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. No signal peptide or TMH reported present.; hypothetical protein	complement(1811729..1812199)	Azoarcus sp. BH72	4606954
YP_933157.1	CDS	azo1653	NC_008702.1	1812617	1815325	D	Putative Autotransporter30% identity to TrEMBL;Q87UU2. Weak homology with hits in the DB. Signal Peptide present. No TMH reported present. Has PF03797;Autotransporter beta-domain;The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.; autotransporter	1812617..1815325	Azoarcus sp. BH72	4610006
YP_933158.1	CDS	azo1654	NC_008702.1	1815335	1815595	R	Homology to cell division topological specificity factor minE.; Family membership; putative cell division topological specificity factor	complement(1815335..1815595)	Azoarcus sp. BH72	4606956
YP_933159.1	CDS	minD	NC_008702.1	1815597	1816409	R	Septum site-determining protein minD (Cell division inhibitor minD).; High confidence in function and specificity; putative septum site-determining protein	complement(1815597..1816409)	Azoarcus sp. BH72	4606957
YP_933160.1	CDS	azo1656	NC_008702.1	1816439	1817209	R	Probable septum site-determining protein minC.; Family membership; putative cell division inhibitor	complement(1816439..1817209)	Azoarcus sp. BH72	4609224
YP_933161.1	CDS	hslO	NC_008702.1	1817301	1818167	R	Putative 33 kDa chaperonin. Homology to hslO of E. coli of 32% (sprot|HSLO_ECOLI) Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity). InterPro: Hsp33 protein (IPR000397) Pfam: Hsp33 protein no signal peptide no TMHs; Family membership; putative 33 kDa chaperonin	complement(1817301..1818167)	Azoarcus sp. BH72	4606958
YP_933162.1	CDS	azo1658	NC_008702.1	1818164	1818496	R	45% Arsen_reductase.IPR006504; Cons_hypoth_ArsC. Pfam:PF03960; ArsC; 1. ArsC:arsenate reductase, catalyzes the reduction of arsenate to arsenite. Probably involved in arsenic resistance.; High confidence in function and specificity; putative arsenate reductase	complement(1818164..1818496)	Azoarcus sp. BH72	4609034
YP_933163.1	CDS	tex	NC_008702.1	1818545	1820866	R	Transcription accessory protein (S1-domain containing RNA binding protein),; High confidence in function and specificity; transcription accessory protein	complement(1818545..1820866)	Azoarcus sp. BH72	4606959
YP_933164.1	CDS	azo1660	NC_008702.1	1820983	1821834	R	Possible aldose 1-epimerase.Aldose 1-epimerase (mutarotase), responsible for the anomeric interconversion of D-glucose and other aldoses between their alpha- and beta-forms. InterPro:IPR008183; Ald1_epimerase. Pfam:PF01263; Aldose_epim; 1.; hypothetical protein	complement(1820983..1821834)	Azoarcus sp. BH72	4609930
YP_933165.1	CDS	azo1661	NC_008702.1	1821839	1824526	R	Conserved hypothetical protein. Homology to cv3676 of C. violaceum of 47% (trembl|Q7NRV4). InterPro: DUF184 (IPR003781). Pfam: CoA binding domain; Acetyltransferase (GNAT) family. No signal peptide. No TMHs; hypothetical protein	complement(1821839..1824526)	Azoarcus sp. BH72	4606960
YP_933166.1	CDS	azo1662	NC_008702.1	1824697	1826376	R	Putative two-component system sensor protein, 3 Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices.; Function unclear; putative two-component system sensor protein	complement(1824697..1826376)	Azoarcus sp. BH72	4606961
YP_933167.1	CDS	tehB	NC_008702.1	1826675	1827214	D	TREMBL:Q8EI75-35% identity, 54% similarity TREMBLnew:AAS81097 InterPro: SAM (and some other nucleotide) binding motif tehB: tellurite resistance protein TehB. Toxin production and resistance responsible for potassium tellurite resistance when present in high copy number, probably by increasing the reduction rate of tellurite to metallic tellurium within the bacterium. otherwise, phenotypically silent.cytoplasmic (potential). was originally (ref.1) thought to be plasmid encoded.InterPro IPR000051; SAM_bind. IPR004537; TehB. Pfam PF03848; TehB; 1. TIGRFAMs:TIGR00477; tehB; 1. INDUCES AGGLUTINATION OF NEURAMINIDASE-TREATED ERYTHROCYTES.; Conserved hypothetical protein; putative tellurite resistance protein	1826675..1827214	Azoarcus sp. BH72	4606962
YP_933168.1	CDS	azo1664	NC_008702.1	1827218	1828321	R	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase	complement(1827218..1828321)	Azoarcus sp. BH72	4609926
YP_933169.1	CDS	azo1665	NC_008702.1	1828320	1829360	D	catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase	1828320..1829360	Azoarcus sp. BH72	4606963
YP_933170.1	CDS	tesA1	NC_008702.1	1829378	1829989	R	Probable acyl-CoA thioesterase. Homology to tesA of E. coli of 42% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase with GDSL-like motif signal peptide no TMH; Family membership; acyl-CoA thioesterase	complement(1829378..1829989)	Azoarcus sp. BH72	4606964
YP_933171.1	CDS	azo1667	NC_008702.1	1829973	1830689	D	Similar to TREMBL:Q82UM8 (55% identity); TREMBL:Q8XYP0 (59% identity); TREMBL:Q7W685 (59% identity). Pfam (PF00005): ABC transporter.; Specificity unclear; putative ABC transporter ATP-binding protein	1829973..1830689	Azoarcus sp. BH72	4609928
YP_933172.1	CDS	serB	NC_008702.1	1830700	1831530	R	Phosphoserine phosphatase, SerB, catalyzes the final step in serine biosynthesis in E. coli. It hydrolyses the phosphate group from phosphoserine to yield serine. Similar to trembl|Q82X56 (54%) and to sprot|SERB_ECOLI (37%). TIGRFAM: phosphoserine phosphatase SerB Pfam (PF00702): haloacid dehalogenase-like hydrolase; Specificity unclear; phosphoserine phosphatase	complement(1830700..1831530)	Azoarcus sp. BH72	4606965
YP_933173.1	CDS	aroF	NC_008702.1	1831527	1832603	R	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase	complement(1831527..1832603)	Azoarcus sp. BH72	4609866
YP_933174.1	CDS	azo1670	NC_008702.1	1832786	1833313	D	Conserved hypothetical secreted protein. Homology to PA2869 of P.aeruginosa of 32% (trembl:Q9HZX7). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	1832786..1833313	Azoarcus sp. BH72	4608346
YP_933175.1	CDS	azo1671	NC_008702.1	1833366	1835738	D	GGDEF/EAL/PAS/PAC-domain containing protein; diguanylate cyclase	1833366..1835738	Azoarcus sp. BH72	4606966
YP_933176.1	CDS	corA	NC_008702.1	1835746	1836711	R	Magnesium and cobalt transport protein CorA. Plays a role in the transport of Magnesium and Cobalt ions. Homolog to E.coli and S.typhimurium, magnesium and cobalt proteins. InterPro:IPR002523; Mg2+_transptCorA. Pfam: PF01544; CorA; 1. THM:2; Function unclear; putative magnesium and cobalt transport protein	complement(1835746..1836711)	Azoarcus sp. BH72	4606967
YP_933177.1	CDS	mfd	NC_008702.1	1836734	1840186	R	Transcription-repair coupling factor (TRCF). NECESSARY FOR STRAND-SPECIFIC REPAIR. A LESION IN THE TEMPLATE STRAND BLOCKS THE RNA POLYMERASE COMPLEX (RNAP). THE RNAP-DNA-RNA COMPLEX IS SPECIFICALLY RECOGNIZED BY TRCF WHICH RELEASES RNAP AND THE TRUNCATED TRANSCRIPT; THE TCRF MAY REPLACE RNAP AT THE LESION SITE AND THEN RECRUIT THE UVRA/B/C REPAIR SYSTEM. mfd: transcription-repair coupling fa; High confidence in function and specificity; transcription-repair coupling factor	complement(1836734..1840186)	Azoarcus sp. BH72	4608518
YP_933178.1	CDS	azo1674	NC_008702.1	1840295	1840948	R	Conserved hypothetical protein. Homology to CV1155 of Chromobacterium violaceum of 35% (gnl|keqq|cvi:CV1155(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(1840295..1840948)	Azoarcus sp. BH72	4609215
YP_933179.1	CDS	azo1675	NC_008702.1	1841025	1841771	R	Probable DNA fragmentation factor 40 kDa subunit (EC 3.-.-.-) (DFF-40) (Caspase-activated deoxyribonuclease) (Caspase-activated DNase) (CAD). Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes,which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate. This family includes a range of diverse phosphoribosyl transferase enzymes TREMBL:Q7WXA5: 29% identity, 47% similarity InterPro:IPR000836; PRtransferase. Pfam: PF00156; Pribosyltran; 1. acid_CoA_mut_C: methylmalonyl-CoA muta Non-secretory protein with low probability of signal peptide (0.001) No transmembrane helices; Function unclear; putative phosphoribosyltransferase	complement(1841025..1841771)	Azoarcus sp. BH72	4606968
YP_933180.1	CDS	pflA	NC_008702.1	1841802	1842875	R	conserved hypothetical pyruvat formate-lyase activiating enzyme. Homology to pflA of M. tuberculosis of 64% (trembl|P95188). no domains predicted no signal peptide no TMHs; Family membership; putative pyruvate formate-lyase activating enzyme	complement(1841802..1842875)	Azoarcus sp. BH72	4606969
YP_933181.1	CDS	azo1677	NC_008702.1	1842957	1843337	R	Conserved hypothetical protein. Homology to Daro03002649 of Dechloromonas aromatica of 39% (gi|41723559|ref|ZP_00150469.1|(NBCI ENTREZ)). No domains predicted. No TMH. No signal peptide.; hypothetical protein	complement(1842957..1843337)	Azoarcus sp. BH72	4609529
YP_933182.1	CDS	azo1678	NC_008702.1	1843392	1844072	R	Putative cyclic nucleotide-binding protein,; Specificity unclear; putative cyclic nucleotide-binding protein	complement(1843392..1844072)	Azoarcus sp. BH72	4606970
YP_933183.1	CDS	azo1679	NC_008702.1	1844113	1844679	R	Hypothetical protein, 38% identity to SwissProt;O26945 Has PF01871;AMMECR1;(IPR002733, DUF 51)This family consists of several AMMECR1 as well as several uncharacterised proteins. The contiguous gene deletion syndrome AMME is characterised by Alport syndrome, midface hypoplasia, mental retardation and elliptocytosis and is caused by a deletion in Xq22.3,comprising several genes including COL4A5, FACL4 and AMMECR1. This family contains sequences from several eukaryotic species as well as archaebacteria and it has been suggested that the AMMECR1 protein may have a basic cellular function, potentially in either the transcription, replication, repair or translation machinery.; Specificity unclear; hypothetical protein	complement(1844113..1844679)	Azoarcus sp. BH72	4606971
YP_933184.1	CDS	azo1680	NC_008702.1	1844660	1845484	R	Hypothetical UPF0103 protein ST2062. This gene is conserved in several species ranging from Caenorhabditis elegans and yeast to plants and micro-organisms although no function has yet been ascribed to the other proteins in this family. TREMBL:Q843N3: 38% identity,52% similarity InterPro:IPR002733; DUF51. IPR002737; DUF52. Pfam: PF01871; AMMECR1; 1. PF01875; UPF0103 Signal peptide present No transmembrane helices holB: DNA polymerase III delta prime sub; Function unclear; hypothetical protein	complement(1844660..1845484)	Azoarcus sp. BH72	4606972
YP_933185.1	CDS	azo1681	NC_008702.1	1845532	1846800	R	Conserved hypothetical membrane protein. TrEMBL; Q82Y76(48% identity). TMHMM2 reporting 14 TMH's present. Signal Peptide not present. Has PF02308;MgtC family;(IPR003416 MgtCSapB_transpt)The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known, but it is thought that MgtC may act as an accessory protein for MgtB, thus mediating magnesium influx into the cytosol. Also included in this family are the Bacillus subtilis SapB protein and several hypothetical proteins. Has PF04093 rod shape-determining protein MreD;IPR007227; MreD (murein formation D) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.; Conserved hypothetical protein; hypothetical protein	complement(1845532..1846800)	Azoarcus sp. BH72	4606973
YP_933186.1	CDS	ispD	NC_008702.1	1846917	1847627	D	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	1846917..1847627	Azoarcus sp. BH72	4606974
YP_933187.1	CDS	ispF	NC_008702.1	1847624	1848112	D	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	1847624..1848112	Azoarcus sp. BH72	4606975
YP_933188.1	CDS	azo1684	NC_008702.1	1848221	1848658	R	Conserved hypothetical protein. Homology to pc0921 of Parachlamydia_UWE25 of 34% (pcu:pc0921(KEGG)). No signal peptide reported to be present. No TMH reported to be present. No domains predicted.; hypothetical protein	complement(1848221..1848658)	Azoarcus sp. BH72	4609097
YP_933189.1	CDS	azo1685	NC_008702.1	1848851	1849654	R	Conserved hypothetical protein. Homology to NE0619 of Nitrosomonas europaea of 44% (trembl:Q82WP5). Has PF06167, IPR010384; Protein of unknown function (DUF980);Family of uncharacterised bacterial sequences. No signal peptide. No TMHs.; hypothetical protein	complement(1848851..1849654)	Azoarcus sp. BH72	4606976
YP_933190.1	CDS	azo1686	NC_008702.1	1849657	1850562	R	Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 42% (tremble:Q7NV15) InterPro: Integral membrane protein DUF6 Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport Pfam: Integral membrane protein DUF6 no signal peptide probable 10 TMHS; Conserved hypothetical protein; hypothetical protein	complement(1849657..1850562)	Azoarcus sp. BH72	4606977
YP_933191.1	CDS	azo1687	NC_008702.1	1850648	1853737	R	Similar to membrane carboxypeptidases.; Family membership; hypothetical protein	complement(1850648..1853737)	Azoarcus sp. BH72	4606978
YP_933192.1	CDS	relA	NC_008702.1	1853847	1856048	D	GTP pyrophosphokinase,; High confidence in function and specificity; GTP diphosphokinase	1853847..1856048	Azoarcus sp. BH72	4606979
YP_933193.1	CDS	ppk	NC_008702.1	1856085	1858166	R	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase	complement(1856085..1858166)	Azoarcus sp. BH72	4609712
YP_933194.1	CDS	ppx	NC_008702.1	1858259	1859809	D	45% Ppx_GppA. Pfam:PF02541; Ppx-GppA; 1.; High confidence in function and specificity; putative exopolyphosphatase	1858259..1859809	Azoarcus sp. BH72	4609612
YP_933195.1	CDS	azo1691	NC_008702.1	1859915	1861012	D	Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.; hypothetical protein	1859915..1861012	Azoarcus sp. BH72	4609617
YP_933196.1	CDS	azo1692	NC_008702.1	1861009	1861785	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7W0L5 (51% identity); TREMBL:Q9A5X8 (46% identity). InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; putative ABC transporter ATP-binding protein	1861009..1861785	Azoarcus sp. BH72	4606980
YP_933197.1	CDS	azo1693	NC_008702.1	1861775	1862713	D	Conserved hypothetical secreted protein. Homology to bb0165 of B. bronchiseptica of 31% (TREMBL:Q7WR07). Pfam: mce related protein This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within, the macrophage. This family contains proteins of unknown function from other bacteria. Signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	1861775..1862713	Azoarcus sp. BH72	4606981
YP_933198.1	CDS	azo1694	NC_008702.1	1862703	1863353	D	Conserved hypothetical protein. Homology to ebA6519 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA6519(KEGG)). no domains predicted. signal peptide present. no TMHs.; hypothetical protein	1862703..1863353	Azoarcus sp. BH72	4606982
YP_933199.1	CDS	azo1695	NC_008702.1	1863402	1865054	D	activates fatty acids by binding to coenzyme A; acyl-CoA synthetase	1863402..1865054	Azoarcus sp. BH72	4606983
YP_933200.1	CDS	paaF2	NC_008702.1	1865171	1865971	D	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	1865171..1865971	Azoarcus sp. BH72	4606984
YP_933201.1	CDS	yjjV	NC_008702.1	1865974	1866795	D	Putative deoxyribonuclease yjjV (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family.; High confidence in function and specificity; putative deoxyribonuclease	1865974..1866795	Azoarcus sp. BH72	4609471
YP_933202.1	CDS	azo1698	NC_008702.1	1866763	1867386	R	Tetracycline repressor protein class G. Similar to SWISSPROT: sprot|TER7_VIBAN (21% Vibrio anguillarum (Listonella anguillarum), tetracycline repressor protein class G). TETR IS THE REPRESSOR OF THE TETRACYCLINE RESISTANCE ELEMENT; ITS AMINO-TERMINAL REGION FORMS A HELIX-TURN-HELIX STRUCTURE AND BINDS DNA. BINDING OF TETRACYCLINE TO TETR REDUCES THE REPRESSOR AFFINITY FOR THE TETRACYCLINE RESISTANCE GENE (TETA) PROMOTER OPERATOR SITES. InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins, tetR family. HTH reporting nucleic acid binding motif.; Family membership; TetR family transcriptional regulator	complement(1866763..1867386)	Azoarcus sp. BH72	4610191
YP_933203.1	CDS	etfB1	NC_008702.1	1867564	1868313	D	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity; electron transfer flavoprotein subunit beta	1867564..1868313	Azoarcus sp. BH72	4606985
YP_933204.1	CDS	etfA1	NC_008702.1	1868313	1869248	D	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 65% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity; electron transfer flavoprotein subunit alpha	1868313..1869248	Azoarcus sp. BH72	4608682
YP_933205.1	CDS	azo1701	NC_008702.1	1869332	1869952	D	Conserved hypothetical membrane protein. Homology to CV1589 of Chromobacterium violaceum of 36% (trembl|Q7NXN7(SRS)). Has PF01891;CbiM;(IPR002751)This integral membrane protein is involved in cobalamin synthesis. No signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	1869332..1869952	Azoarcus sp. BH72	4608678
YP_933206.1	CDS	azo1702	NC_008702.1	1870013	1871812	D	Acyl-CoA dehydrogenase short/branched chain specific mitochondrial precursor (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase). Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA isobutyryl-CoA and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent. Entry name TREMBL:Q8Y0W8 Identities = 358/596 (60%) InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1.; Family membership; acyl-CoA dehydrogenase	1870013..1871812	Azoarcus sp. BH72	4606986
YP_933207.1	CDS	cbf2	NC_008702.1	1871903	1872685	R	Cell binding factor 2 precursor (Major antigen peb4A). Homology to cbf2 of C. jejuni of 34% (sprot|CBF2_CAMJE). Belongs to the ppic/parvulin rotamase family InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain signal peptide no TMH; Family membership; putative cell binding factor	complement(1871903..1872685)	Azoarcus sp. BH72	4606987
YP_933208.1	CDS	azo1704	NC_008702.1	1872682	1872975	R	Region start changed from 1873054 to 1872976 (-78 bases); putative BolA-like protein	complement(1872682..1872975)	Azoarcus sp. BH72	4608423
YP_933209.1	CDS	yciI	NC_008702.1	1872972	1873271	R	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein	complement(1872972..1873271)	Azoarcus sp. BH72	4606988
YP_933210.1	CDS	ispZ	NC_008702.1	1873271	1873879	R	Involved in cell division; probably involved in intracellular septation; intracellular septation protein A	complement(1873271..1873879)	Azoarcus sp. BH72	4610161
YP_933211.1	CDS	azo1707	NC_008702.1	1873923	1874336	R	Conserved hypothetical globin-like protein. Homology to bd2638 of B. bacteriovorus of 57% (tremblnew|CAE80431). Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. However they can also be found in some protozoa and plants as well. InterPro: Protozoan/cyanobacterial globins (IPR001486) Pfam: Bacterial-like globin. no signal peptide. no TMHs; Family membership; globin-like protein	complement(1873923..1874336)	Azoarcus sp. BH72	4609098
YP_933212.1	CDS	envZ1	NC_008702.1	1874441	1875826	R	Probable osmolarity sensor protein EnvZ,; Specificity unclear; osmolarity sensor protein	complement(1874441..1875826)	Azoarcus sp. BH72	4606989
YP_933213.1	CDS	ompR	NC_008702.1	1875852	1876598	R	part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator	complement(1875852..1876598)	Azoarcus sp. BH72	4608671
YP_933214.1	CDS	azo1710	NC_008702.1	1876813	1877142	D	Hypothetical secreted protein. No homologs in the database. Signal Peptide present. No TMHs. No domains predicted; hypothetical protein	1876813..1877142	Azoarcus sp. BH72	4609446
YP_933215.1	CDS	azo1711	NC_008702.1	1877212	1877901	D	Conserved hypothetical glycoprotease. Homology to yeaZ of N. europae of 41% (trembl|Q82US9). InterPro: Glycoprotease (M22) metallo-protease family (IPR000905). Tigrfam: gcp: metalloendopeptidase putative glycoprotease family. Pfam: Glyocprotease family. no signal peptide. no TMHs.; Family membership; glycoprotease	1877212..1877901	Azoarcus sp. BH72	4606990
YP_933216.1	CDS	azo1712	NC_008702.1	1877931	1878353	D	Conserved hypothetical ribosomal-protein-alanine acetyltransferase. Homology to ebA6491 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA6491(KEGG)). Pfam: Acetyltransferase (GNAT) family. Tigrfam: ribosomal-protein-alanine acetyltransferase. No signal peptide. No TMHs.; Conserved hypothetical protein; putative ribosomal-protein-alanine acetyltransferase	1877931..1878353	Azoarcus sp. BH72	4606991
YP_933217.1	CDS	azo1713	NC_008702.1	1878350	1879201	D	Putative DNA polymerase-related protein,bacteriophage-type. TIGRFAM: rad23: UV excision repair protein Rad23; Specificity unclear; DNA-directed DNA polymerase	1878350..1879201	Azoarcus sp. BH72	4606992
YP_933218.1	CDS	azo1714	NC_008702.1	1879223	1880473	R	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Homolog to the hypothetical protein ygeD, a putative resistence protein from Y. pestis(by similarity). 2A0121: H+ Antiporter protein; High confidence in function and specificity; lysophospholipid transporter LplT	complement(1879223..1880473)	Azoarcus sp. BH72	4606993
YP_933219.1	CDS	rbcR	NC_008702.1	1880629	1881549	D	Trans-acting transcriptional regulator of RuBisCO genes expression Putative HTH-type transcriptional regulator Contains 1 HTH lysR-type DNA-binding domain,belonds to the LysR family InterPro: Bacterial regulatory protein LysR family ModE_repress: ModE molybdate transport 32% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1; High confidence in function and specificity; RuBisCO operon transcriptional regulator (RbcR)	1880629..1881549	Azoarcus sp. BH72	4606994
YP_933220.1	CDS	radA	NC_008702.1	1881549	1882919	D	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA	1881549..1882919	Azoarcus sp. BH72	4609695
YP_933221.1	CDS	azo1717	NC_008702.1	1882984	1883250	R	Hypothetical protein . Extremely weak homology with any hits in the database. No Features,signal Peptide,motifs are known domains present.; hypothetical protein	complement(1882984..1883250)	Azoarcus sp. BH72	4609690
YP_933222.1	CDS	azo1718	NC_008702.1	1883575	1884198	D	Hypothetical protein, has very weak homology with hits in the Database(TrEMBL;Q63I29) Coils2 program reporting presence of coiled-coiled.; hypothetical protein	1883575..1884198	Azoarcus sp. BH72	4606995
YP_933223.1	CDS	azo1719	NC_008702.1	1884227	1885696	D	Conserved hypothetical protein. Homology to ebA7025 of Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA7025(KEGG)). Pfam: Glycos_transf_2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. No signal peptide. No TMHs; hypothetical protein	1884227..1885696	Azoarcus sp. BH72	4606996
YP_933224.1	CDS	azo1720	NC_008702.1	1885699	1886832	D	Family membership; glycosyltransferase	1885699..1886832	Azoarcus sp. BH72	4606997
YP_933225.1	CDS	azo1721	NC_008702.1	1886756	1887814	R	Similar to waaQ.; Family membership; heptosyltransferase	complement(1886756..1887814)	Azoarcus sp. BH72	4606998
YP_933226.1	CDS	azo1722	NC_008702.1	1887936	1888283	D	Hypothetical protein, weak homology with hits. TrEMBL;Q9KPT2(45% identity) No domains, repeats, motifs or features present.; hypothetical protein	1887936..1888283	Azoarcus sp. BH72	4606999
YP_933227.1	CDS	azo1723	NC_008702.1	1888362	1889357	D	Conserved hypothetical protein. Homology to blr5713 of B.japonicum of 45% (tremble:Q89IC6). No domains predicted. No TMHs. SignalP 3.0 predicts no signal peptide.; hypothetical protein	1888362..1889357	Azoarcus sp. BH72	4607000
YP_933228.1	CDS	azo1724	NC_008702.1	1889404	1889835	D	Conserved hypothetical protein. Homology to SMA1058 of S.meliloti of 48% (trembl:Q92ZB7). No domains predicted. No signal peptide. No TMHs; hypothetical protein	1889404..1889835	Azoarcus sp. BH72	4607001
YP_933229.1	CDS	glgB1	NC_008702.1	1889835	1891748	D	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein	1889835..1891748	Azoarcus sp. BH72	4607002
YP_933230.1	CDS	pep1	NC_008702.1	1891732	1893780	D	O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety.Probable glucanohydrolase Pep1B. Could convert glycogen into units that may be subsequently converted into trehalose.Belongs to family 13 of glycosyl hydrolases. Glge subfamily. 47% Alpha_amyl_cat. Pfam:PF00128; alpha-amylase; 1.; High confidence in function and specificity; putative glucanohydrolase	1891732..1893780	Azoarcus sp. BH72	4608885
YP_933231.1	CDS	treS	NC_008702.1	1893796	1897116	D	Trehalose synthase(Maltose alpha-D-glucosyltransferase).Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation. 54% Alp_amyl_cat_sub.IPR006047; Alpha_amyl_cat.InterPro: Glycoside hydrolase family 13. Pfam:PF00128; alpha-amylase; 1.; High confidence in function and specificity; putative trehalose synthase	1893796..1897116	Azoarcus sp. BH72	4609518
YP_933232.1	CDS	azo1728	NC_008702.1	1897139	1897705	R	Conserved hypothetical secreted protein. Homology to BPP3320 of B.bronchiseptica of 31% (tremble:Q7W5H1). No domains predicted. Signap P reporting signal peptide. No TMH reported.; Conserved hypothetical protein; hypothetical protein	complement(1897139..1897705)	Azoarcus sp. BH72	4609966
YP_933233.1	CDS	azo1729	NC_008702.1	1897982	1899142	D	Conserved hypothetical protein. Homology to mm2747 of M. mazei of 39% (trembl|Q8PTG8(SRS). no domains predicted. no TMHs. no signal peptide.; hypothetical protein	1897982..1899142	Azoarcus sp. BH72	4607003
YP_933234.1	CDS	azo1730	NC_008702.1	1899198	1899947	D	Conserved hypothetical protein. Homology to ebA6994 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA6994(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1899198..1899947	Azoarcus sp. BH72	4607004
YP_933235.1	CDS	azo1731	NC_008702.1	1899978	1900238	D	Hypothetical membrane protein. No homology to the data bank. No domain prediction. No signal peptide. 1 TMH; hypothetical protein	1899978..1900238	Azoarcus sp. BH72	4607005
YP_933236.1	CDS	azo1732	NC_008702.1	1900291	1901157	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Family membership; short-chain dehydrogenase	1900291..1901157	Azoarcus sp. BH72	4607006
YP_933237.1	CDS	azo1733	NC_008702.1	1901147	1901629	R	Hypothetical protein with unknown function. Domain predicted by Pfam, PF01381 Helix-turn-helix.; hypothetical protein	complement(1901147..1901629)	Azoarcus sp. BH72	4607007
YP_933238.1	CDS	azo1734	NC_008702.1	1901759	1904050	D	Entry name TREMBL:Q89PM4 Identities = 257/546 (47%) Prediction: Non-secretory protein Signal peptide probability: 0.018 Number of predicted TMHs: 0 pts-lac: PTS system lactose/cellobios; hypothetical protein	1901759..1904050	Azoarcus sp. BH72	4607008
YP_933239.1	CDS	azo1735	NC_008702.1	1904135	1904476	D	Conserved hypothetical protein. Homology to rO1139 of S. meliloti of 48% (trembl|Q92QZ6). No domains predicted. No signal peptide. No TMHs; hypothetical protein	1904135..1904476	Azoarcus sp. BH72	4607009
YP_933240.1	CDS	azo1736	NC_008702.1	1904512	1905063	R	Hypothetical protein. No good homology with any Hits in the database.; hypothetical protein	complement(1904512..1905063)	Azoarcus sp. BH72	4607010
YP_933241.1	CDS	azo1737	NC_008702.1	1905343	1906143	D	Conserved hypothetical membrane protein. Homology to ebA6987 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA6987(KEGG)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	1905343..1906143	Azoarcus sp. BH72	4607011
YP_933242.1	CDS	azo1738	NC_008702.1	1906182	1906676	D	Hypothetical protein has weak homology to Transglycosylase of penicillin-binding protein 1c(pbpC).TrEMBL:Q8ZN47(56%). ***Contains PRC-barrel domain(pfam05239). The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins conserved in all known euryarchaea are composed entirely of a single stand-alone copy of the domain. No Signal Peptide reported. No TMH's reported.; hypothetical protein	1906182..1906676	Azoarcus sp. BH72	4607012
YP_933243.1	CDS	azo1739	NC_008702.1	1906742	1907686	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:O32291 (45% identity); SWISSPROT:P54554 (28% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short chain dehydrogenase	complement(1906742..1907686)	Azoarcus sp. BH72	4607013
YP_933244.1	CDS	azo1740	NC_008702.1	1907834	1908745	D	conserved hypothetical protein, 49% identity to TrEMBL;Q7W766. Has SMART;SM00559;Ku78;Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen;(IPR006164);This is a single stranded DNA- and ATP-depedent helicase that has a role in chromosome translocation. This is a domain of unknown function C-terminal to its von Willebrand factor A domain, that also occurs in bacterial hypothetical proteins.; hypothetical protein	1907834..1908745	Azoarcus sp. BH72	4607014
YP_933245.1	CDS	ligD	NC_008702.1	1908782	1911427	D	catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase	1908782..1911427	Azoarcus sp. BH72	4607015
YP_933246.1	CDS	azo1742	NC_008702.1	1911701	1912390	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal peptide present. No TMHs.; hypothetical protein	1911701..1912390	Azoarcus sp. BH72	4607016
YP_933247.1	CDS	azo1743	NC_008702.1	1912374	1913198	R	Conserved hypothetical protein. Homology to ebA6983 of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA6983(KEGG)). Pfam: N-formylglutamate amidohydrolase. Formylglutamate amidohydrolase (FGase) catalyses the terminal reaction in the five-step pathway for histidine utilisation in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolysed to produce L-glutamate plus formate. no signal peptide. no TMHs; hypothetical protein	complement(1912374..1913198)	Azoarcus sp. BH72	4607017
YP_933248.1	CDS	azo1744	NC_008702.1	1913153	1914424	R	Hypothetical protein,32% identity (49% similarity) to SwissProt;O27977 Has PF04107;Glutamate-cysteine ligase family 2(GCS2);(IPR006336)Also known as gamma-glutamylcysteine synthetase and gamma-ECS. This enzyme catalyses the first and rate limiting step in de novo glutathione biosynthesis. Members of this family are found in archaea, bacteria and plants. May and Leaver [1] discuss the possible evolutionary origins of glutamate-cysteine ligase enzymes in different organisms and suggest that it evolved independently in different eukaryotes,from an ancestral bacterial enzyme. They also state that Arabidopsis thaliana gamma-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and Escherichia coli homologues. In plants, there are separate cytosolic and chloroplast forms of the enzyme.; glutamate-cysteine ligase	complement(1913153..1914424)	Azoarcus sp. BH72	4607018
YP_933249.1	CDS	rimK	NC_008702.1	1914421	1915890	R	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) rimK_fam: S6 modification enzyme RimK; Specificity unclear; ribosomal protein S6 modification protein-like protein	complement(1914421..1915890)	Azoarcus sp. BH72	4607019
YP_933250.1	CDS	azo1746	NC_008702.1	1915934	1916671	R	Conserved hypothetical protein. Homology to TdenA01000334 of Thiobacillus denitrificans of 67% (gi|52008038|ref|ZP_00335415.1|(NBCI ENTREZ)). No domains present. No signal peptide. No TMHs.; hypothetical protein	complement(1915934..1916671)	Azoarcus sp. BH72	4609727
YP_933251.1	CDS	azo1747	NC_008702.1	1916675	1917442	R	Hypothetical secreted protein. No homology to the data bank. No TMHs Signal Peptide present. Has PS50914; BON;The BON (bacterial OsmY and nodulation) domain is found in the bacterial osmotic-shock-resistance protein OsmY, a family of haemolysins, a group of nodulation specificity proteins and secretory channels, and several hypothetical proteins. It is typically about 60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions.; hypothetical protein	complement(1916675..1917442)	Azoarcus sp. BH72	4607020
YP_933252.1	CDS	azo1748	NC_008702.1	1917567	1918007	D	Hypothetical protein yhcV. TREMBL:Q92V69:54%identity, 76% similarity. TREMBL:Q81UY6 Pfam:CBS domain, Anticodon binding domain. TIGRFAM: KpsF/GutQ family proteins. No signal peptide or transmembrane helix reported. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. Pairs of CBS domains dimerise to form a stable globular domain. Two CBS domains are found in inosine-monophosphate dehydrogenase from all species, however the CBS domains are not needed for activity. CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role. The region containing the CBS domains in Cystathionine-beta synthase is involved in regulation by S-AdoMet.. A number of disease states are associated with CBS-containing proteins including homocystinuria, Becker's and Thomsen disease. InterPro: CBS domain urease_gam: urease gamma subunit; Function unclear; hypothetical protein	1917567..1918007	Azoarcus sp. BH72	4607021
YP_933253.1	CDS	azo1749	NC_008702.1	1918070	1918228	R	Conserved hypothetical membrane protein. Homology to r02018 of S. meliloti of 72% (trembl|Q92K67(SRS). no damains predicted .signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(1918070..1918228)	Azoarcus sp. BH72	4607022
YP_933254.1	CDS	azo1750	NC_008702.1	1918212	1918685	D	Hypothetical membrane protein. No homology of the entire protein to the data bank. Has DUF1328(Protein of Unknown family) domain. PF07043;IPR009760; This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. no signal peptide. 3 TMHs; hypothetical protein	1918212..1918685	Azoarcus sp. BH72	4607023
YP_933255.1	CDS	azo1751	NC_008702.1	1918699	1919052	D	Conserved hypothetical secreted protein. Homology to ebA6968 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA6968(KEGG)). Pfam: Putative phospholipid-binding domain This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	1918699..1919052	Azoarcus sp. BH72	4607024
YP_933256.1	CDS	azo1752	NC_008702.1	1919143	1919466	D	Conserved hypothetical secreted protein: Homology to ne0129 of N. europaea of 43% (trembl|Q82XW6). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	1919143..1919466	Azoarcus sp. BH72	4607025
YP_933257.1	CDS	cls2	NC_008702.1	1919438	1920847	D	Function:- Cardiolipin synthetase (CL synthase),cls. Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Entry name :-SWISSPROT:CLS_ECOLI Prim. accession # P31071 InterPro:IPR001736; PLD. Identities = 114/379 (30%) Pfam:PF00614; PLDc; 2. TMhelix=1 Signal peptide probability: 1.0; Family membership; putative cardiolipin synthetase	1919438..1920847	Azoarcus sp. BH72	4607026
YP_933258.1	CDS	azo1754	NC_008702.1	1920896	1921315	D	Conserved hypothetical membrane protein. Homology Avin02003871 of Azotobacter vinelandii of 47% (gi|53610588|ref|ZP_00089122.2|(NBCI ENTREZ)). Has PF03653, Uncharacterised protein family (UPF0093). Interpro: IPR005265; Cons_hypoth701; It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	1920896..1921315	Azoarcus sp. BH72	4608493
YP_933259.1	CDS	azo1755	NC_008702.1	1921312	1921959	R	Conserved hypothetical membrane protein. Homology ebA159 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA159(KEGG)). No domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1921312..1921959)	Azoarcus sp. BH72	4607027
YP_933260.1	CDS	qoxB	NC_008702.1	1922011	1922682	D	Probable quniol oxidase, subunit II. Homology to qoxB of Rhodobacter sphaeroides of 41% (gi|4416093|gb|AAD20226.1|(NBCI ENTREZ)). InterPro: Cytochrome c oxidase subunit II (IPR002429); Cu(A) centre of cytochrome c oxidase, subunit II and nitrous oxide reductase (IPR001505). Pfam: Cytochrome c oxidase subunit II, periplasmic. no signal peptide. 2 TMHs; Family membership; quniol oxidase subunit II	1922011..1922682	Azoarcus sp. BH72	4607028
YP_933261.1	CDS	qoxA	NC_008702.1	1922679	1925261	D	Probable quinol oxidase, subunit I. Homology to qoxA of R. sphaeroides of 52% (trembl|Q9Z605). InterPro: Cytochrome c oxidase subunit III (IPR000298); Cytochrome coxidase, subunit I (IPR000883) Pfam: Cytochrom C and quinol oxidase poly polypeptide signal peptide 17 TMHs; Family membership; quinol oxidase subunit I	1922679..1925261	Azoarcus sp. BH72	4609685
YP_933262.1	CDS	azo1758	NC_008702.1	1925258	1925599	D	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 3 TMHs; hypothetical protein	1925258..1925599	Azoarcus sp. BH72	4609684
YP_933263.1	CDS	azo1759	NC_008702.1	1925590	1926420	D	Conserved hypothetical membrane protein. Homology to Avin02003353 of Azotobacter vinelandii of 48% (gi|53610930|ref|ZP_00342175.1|(NBCI ENTREZ)). No domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein; hypothetical protein	1925590..1926420	Azoarcus sp. BH72	4607029
YP_933264.1	CDS	azo1760	NC_008702.1	1926417	1927421	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8KUH7 (41% identity); SWISSPROT:P14802 (30% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short chain dehydrogenase	1926417..1927421	Azoarcus sp. BH72	4607030
YP_933265.1	CDS	azo1761	NC_008702.1	1927438	1931043	R	Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748).; Specificity unclear; hypothetical protein	complement(1927438..1931043)	Azoarcus sp. BH72	4607031
YP_933266.1	CDS	azo1762	NC_008702.1	1931040	1932170	R	Conserved hypothetical membrane protein. Homology to XCC0079 of Xanthomonas campestris (trembl|Q8PEA2(SRS)). InterPro:IPR002549; UPF0118. Pfam PF01594; domain of DUF20 present. no signal peptide. 8 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1931040..1932170)	Azoarcus sp. BH72	4607032
YP_933267.1	CDS	mucD3	NC_008702.1	1932167	1933585	R	Probable serine protease MucD. Homology to mucD of P. aeruginosa of 40% (trembl|Q57155). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serine protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940); PDZ domain (also known as DHR or GLGF) (IPR001478) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity; serine protease MucD	complement(1932167..1933585)	Azoarcus sp. BH72	4607033
YP_933268.1	CDS	azo1764	NC_008702.1	1933759	1934097	D	Conserved hypothetical secreted protein. Homology to bb3588 of B. bronchiseptica of 41% (trembl|Q7WGK1). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	1933759..1934097	Azoarcus sp. BH72	4609285
YP_933269.1	CDS	azo1765	NC_008702.1	1934286	1934459	D	Conserved hypothetical membrane protein. Homology to Atu4467 of Agrobacterium tumefaciens of 58% (trembl|Q8U7I2). Has PF07043, Protein of unknown function (DUF1328);IPR009760;This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	1934286..1934459	Azoarcus sp. BH72	4607034
YP_933270.1	CDS	ndh1	NC_008702.1	1934490	1935986	R	Probable NADH dehydrogenase. Homology to ndh of P. fluorescens of 48% (trembl|Q9KGX0). TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro: FAD-dependent pyridine nucleotide-dislphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disluphide oxidoreductase no signal peptide no TMHs; Family membership; NADH dehydrogenase	complement(1934490..1935986)	Azoarcus sp. BH72	4607035
YP_933271.1	CDS	azo1767	NC_008702.1	1936009	1936383	R	Conserved hypothetical protein. Homology to an orf of Polyangium cellulosum of 69% (tremble:Q9L8D1). Has PF07100;(IPR009794)Protein of unknown function (DUF1362);This family consists of several hypothetical bacterial proteins of around 125 resides in length. The function of this family is unknown. No signal peptide or TMH reported present.; hypothetical protein	complement(1936009..1936383)	Azoarcus sp. BH72	4609348
YP_933272.1	CDS	azo1768	NC_008702.1	1936817	1937137	D	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domains predicted no signal peptide 1 TMH; hypothetical protein	1936817..1937137	Azoarcus sp. BH72	4607036
YP_933273.1	CDS	azo1769	NC_008702.1	1937286	1938023	R	Conserved hypothetical protein. Weak homology with hits in the database. Coils2 program predicts presence of coiled coil.; hypothetical protein	complement(1937286..1938023)	Azoarcus sp. BH72	4607037
YP_933274.1	CDS	azo1770	NC_008702.1	1938484	1938891	D	Conserved hypothetical DnaK suppressor protein. Homology to BPSS2280 of Burkholderia pseudomallei of 34% (gnl|keqq|bps:BPSS2280(KEGG). Has PF01258, Prokaryotic dksA/traR C4-type zinc finger; IPR000962 Znf_DskA/TraR; The dksA gene product suppresses the temperature-sensitive growth and filamentation of a dnaK deletion mutant of Escherichia coli. Gene knockout and deletion experiments have shown the gene to be non-essential, mutations causing a mild sensitivity to UV light, but not affecting DNA recombination. The protein contains a C-terminal region thought to fold into a 4-cysteine zinc finger. Other proteins found to contain a similar domain include the traR gene product, present on the conjugative plasmid F,and several hypothetical proteins from bacteria and bacteriophages. No TMHs. No signal peptide.; Conserved hypothetical protein; DnaK suppressor protein	1938484..1938891	Azoarcus sp. BH72	4607038
YP_933275.1	CDS	cioA	NC_008702.1	1938905	1940323	D	Probable cyanide insensitive terminal oxidase,subunit I Homology to cioA of P. aeruginose of 44% (TREMBL:O07440) InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no signal peptide no TMHs; High confidence in function and specificity; cyanide insensitive terminal oxidase subunit I	1938905..1940323	Azoarcus sp. BH72	4607039
YP_933276.1	CDS	cioB	NC_008702.1	1940316	1941338	D	Probable cyanide insensitive terminal oxidase,subunit II. Homology to cioB of P. aeruginosa of 40% (trembl|O07441). Tigrfam: cydB: cytochrome d ubiquinol oxidase, subunit II Pfam: cytochrome oxidase, subunit II no signal peptide 8 TMHs; High confidence in function and specificity; cyanide insensitive terminal oxidase subunit II	1940316..1941338	Azoarcus sp. BH72	4608483
YP_933277.1	CDS	azo1773	NC_008702.1	1941818	1942150	D	Conserved hypothetical protein. Homology to an orf of P. putida of 58% (trembl|O68643). no TMHs. no signal peptide. No domains predicted.; hypothetical protein	1941818..1942150	Azoarcus sp. BH72	4608484
YP_933278.1	CDS	azo1774	NC_008702.1	1942244	1943044	D	Conserved hypothetical protein. Homology to Avin02003958 of Azotobacter vinelandii of 38% (gi|53610498|ref|ZP_00089565.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1942244..1943044	Azoarcus sp. BH72	4607040
YP_933279.1	CDS	azo1775	NC_008702.1	1943128	1943709	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	complement(1943128..1943709)	Azoarcus sp. BH72	4607041
YP_933280.1	CDS	azo1776	NC_008702.1	1943822	1944037	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	1943822..1944037	Azoarcus sp. BH72	4607042
YP_933281.1	CDS	azo1777	NC_008702.1	1944084	1945133	D	Hypothetical LuxR-family transcriptional regulator. Similarity to other known proteins (dctR or narP or esaR) only in the domain part. Pfam: PF00196 Bacterial regulatory proteins, luxR family. HTH reporting nucleic acid binding motif. The 'helix-turn-helix' DNA-binding motif of this protein is located in the C-terminal section of the sequence.; Conserved hypothetical protein; LuxR family transcriptional regulator	1944084..1945133	Azoarcus sp. BH72	4607043
YP_933282.1	CDS	azo1778	NC_008702.1	1945382	1945816	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 3 TMHs; hypothetical protein	1945382..1945816	Azoarcus sp. BH72	4607044
YP_933283.1	CDS	ampD1	NC_008702.1	1945848	1946708	D	This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). InterPro (IPR002502): N-acetylmuramoyl-L-alanine amidase (family 2). Pfam (PF01510): N-acetylmuramoyl-L-alanine amidase.; Family membership; N-acetylmuramoyl-L-alanine amidase	1945848..1946708	Azoarcus sp. BH72	4607045
YP_933284.1	CDS	azo1780	NC_008702.1	1946826	1947452	D	Hypothetical protein. no homology of the entire protein to the data bank InterPro: Putative peptidoglycan binding domain 1 (IPR002477) Pfam: Putative peptidoglycan binding domain 1 no signal peptide no TMHs; hypothetical protein	1946826..1947452	Azoarcus sp. BH72	4608312
YP_933285.1	CDS	azo1781	NC_008702.1	1948908	1949294	R	Conserved hypothetical protein. Homology to map2952a of M. paratuberculosis of 51% (AAS05269). Pfam: CahB; Rho terminator factor, N-terminal. domain no signal peptide. no TMHs; hypothetical protein	complement(1948908..1949294)	Azoarcus sp. BH72	4607046
YP_933286.1	CDS	azo1782	NC_008702.1	1949308	1950150	R	Conserved hypothetical protein. Homology to mlr2853 of M. loti of 31% (trembl|Q98HI7). Tigrfam: xth: exodeoxyribonuclease III (xth). All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family I. no signal peptide. no TMHs; hypothetical protein	complement(1949308..1950150)	Azoarcus sp. BH72	4607047
YP_933287.1	CDS	azo1783	NC_008702.1	1950122	1952401	R	Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(1950122..1952401)	Azoarcus sp. BH72	4607048
YP_933288.1	CDS	bfr3	NC_008702.1	1952414	1952968	R	Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis.InterPro: Bacterioferritin. Non-secretory protein bfr: bacterioferritin; High confidence in function and specificity; putative bacterioferritin	complement(1952414..1952968)	Azoarcus sp. BH72	4607049
YP_933289.1	CDS	azo1785	NC_008702.1	1953247	1954419	D	InterPro: Glycosyl transferases group 1; Family membership; glycosyltransferase	1953247..1954419	Azoarcus sp. BH72	4608388
YP_933290.1	CDS	azo1786	NC_008702.1	1954400	1954948	D	Conserved hypothetical phosphoesterase family protein. Homology to ebA6940 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebA6940(KEGG)). InterPro IPR008934; AcPase_VanPerase. IPR000326; PA_PTPase. Pfam PF01569; PAP2; Number of predicted TMHs: 3#. Prediction: Non-secretory protein Signal peptide probability: 0.000; Conserved hypothetical protein; phosphoesterase family protein	1954400..1954948	Azoarcus sp. BH72	4607050
YP_933291.1	CDS	azo1787	NC_008702.1	1954864	1955775	R	TIGR00093: conserved hypothetical protein; Function unclear; hypothetical protein	complement(1954864..1955775)	Azoarcus sp. BH72	4607051
YP_933292.1	CDS	azo1788	NC_008702.1	1955772	1956905	R	InterPro: Glycosyl transferases group 1; Family membership; glycosyltransferase	complement(1955772..1956905)	Azoarcus sp. BH72	4607052
YP_933293.1	CDS	azo1789	NC_008702.1	1957010	1957564	R	Conserved hypothetical protein. Homology to bp0770 of B. pertussis of 37% (TrEMBL:Q7VZW1). no domains reported. no signal peptide. no TMHs; hypothetical protein	complement(1957010..1957564)	Azoarcus sp. BH72	4607053
YP_933294.1	CDS	rpoN2	NC_008702.1	1957602	1959068	R	RNA polymerase sigma-54 factor. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|RP54_ALCEU (46% Alcaligenes eutrophus (Ralstonia eutropha), RpoN or NtrA) / sprot|RP54_ECOLI (41% Escherichia coli, RpoN or NtrA) Pfam:PF00309 Sigma54_AID. PF04963 Sigma54_CBD. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; RNA polymerase sigma-54 factor	complement(1957602..1959068)	Azoarcus sp. BH72	4607054
YP_933295.1	CDS	azo1791	NC_008702.1	1959413	1960084	D	Conserved hypothetical secreted protein. Homology to ebA6930 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	1959413..1960084	Azoarcus sp. BH72	4609801
YP_933296.1	CDS	azo1792	NC_008702.1	1960085	1961215	D	Conserved hypothetical membrane protein. Homology to xcc0923 of X. campestris of 46% (trembl|Q8PC30). InterPro: Uncharacterized protein family UPF0003 (IPR006685). Pfam: Mechanosensitive ion chanell. Mechanosensitive (MS) channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. no signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	1960085..1961215	Azoarcus sp. BH72	4607055
YP_933297.1	CDS	azo1793	NC_008702.1	1961212	1962507	D	Conserved hypothetical protein.Weak Homology with Hits in the Database. Has IPR000967 Znf_NFX1;(SMART;SM00438)This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C, where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C. No signal peptide or TMH reported present.; hypothetical protein	1961212..1962507	Azoarcus sp. BH72	4607056
YP_933298.1	CDS	glgX	NC_008702.1	1962504	1964684	D	Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1.; High confidence in function and specificity; putative glycogen debranching enzyme	1962504..1964684	Azoarcus sp. BH72	4607057
YP_933299.1	CDS	azo1795	NC_008702.1	1964688	1965785	D	DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein.; Specificity unclear; hypothetical protein	1964688..1965785	Azoarcus sp. BH72	4608888
YP_933300.1	CDS	glgB2	NC_008702.1	1965782	1967599	D	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein	1965782..1967599	Azoarcus sp. BH72	4607058
YP_933301.1	CDS	glgC	NC_008702.1	1967706	1968920	D	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase	1967706..1968920	Azoarcus sp. BH72	4608886
YP_933302.1	CDS	treZ	NC_008702.1	1968917	1970977	D	Malto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1.; Specificity unclear; putative malto-oligosyltrehalose trehalohydrolase	1968917..1970977	Azoarcus sp. BH72	4608887
YP_933303.1	CDS	azo1799	NC_008702.1	1971003	1976207	D	amylomaltase; acts to release glucose from maltodextrins; putative bifunctional 4-alpha-glucanotransferase/malto-oligosyltrehalose synthase	1971003..1976207	Azoarcus sp. BH72	4609967
YP_933304.1	CDS	glk1	NC_008702.1	1976211	1977182	R	Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 34% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1.; High confidence in function and specificity; putative glucokinase	complement(1976211..1977182)	Azoarcus sp. BH72	4607059
YP_933305.1	CDS	glgA	NC_008702.1	1977251	1978927	D	Glycogen synthase (Starch [bacterial glycogen] synthase) GlgA. Synthesizes alpha-14-glucan chains using ADP-glucose. 46% Glyco_trans_1. Pfam:PF00534; Glycos_transf_1; 1.; High confidence in function and specificity; putative glycogen synthase	1977251..1978927	Azoarcus sp. BH72	4608889
YP_933306.1	CDS	azo1802	NC_008702.1	1978903	1979856	R	67% Epimerase_Dh. Pfam: PF01370; Epimerase; 1. No signal peptide.; Family membership; putative dTDP-glucose 4,6-dehydratase	complement(1978903..1979856)	Azoarcus sp. BH72	4608884
YP_933307.1	CDS	azo1803	NC_008702.1	1979858	1980823	R	Conserved hypothetical glycosyltransferase. Homology to ebA6914 of Azoarcus sp. EbN1 of 72% (gnl|keqq|eba:ebA6914(KEGG)). Pfam: Glycos_transf_1. Interpro: Glycosyl transferase, group 1. Proteins containign this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis,lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid. No signal peptide. No TMHs.; Conserved hypothetical protein; glycosyltransferase	complement(1979858..1980823)	Azoarcus sp. BH72	4607060
YP_933308.1	CDS	azo1804	NC_008702.1	1980849	1981829	R	Hypothetical 55.3 kDa protein in thcA 5region (ORF1).; High confidence in function and specificity; membrane-anchored glycosyltransferase	complement(1980849..1981829)	Azoarcus sp. BH72	4607061
YP_933309.1	CDS	azo1805	NC_008702.1	1981826	1983562	R	Hypothetical conserved hypothetical cabamoyltransferase. Homology to sco6480 of S. coelicolor of 49% (trembl|Q8CJN9). Pfam: Carbamyltransferase. no signal peptide. no TMHS; Conserved hypothetical protein; carbamoyltransferase	complement(1981826..1983562)	Azoarcus sp. BH72	4607062
YP_933310.1	CDS	waaF1	NC_008702.1	1983567	1984781	R	ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-). pdxJ: pyridoxal phosphate biosynthetic; High confidence in function and specificity; ADP-heptose--LPS heptosyltransferase II	complement(1983567..1984781)	Azoarcus sp. BH72	4607063
YP_933311.1	CDS	azo1807	NC_008702.1	1984769	1985425	R	Hypothetical protein yaeD.; High confidence in function and specificity; heptose phosphatase	complement(1984769..1985425)	Azoarcus sp. BH72	4610105
YP_933312.1	CDS	azo1808	NC_008702.1	1985416	1986156	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8YLL2 (35% identity); TREMBL:Q9HWN3 (37% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	complement(1985416..1986156)	Azoarcus sp. BH72	4607064
YP_933313.1	CDS	azo1809	NC_008702.1	1986153	1987412	R	Hypothetical protein Rv0486/MT0504/Mb0496. InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(1986153..1987412)	Azoarcus sp. BH72	4607065
YP_933314.1	CDS	azo1810	NC_008702.1	1987667	1988008	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	1987667..1988008	Azoarcus sp. BH72	4607066
YP_933315.1	CDS	azo1811	NC_008702.1	1987987	1988523	R	Conserved hypothetical membrane protein. Homology to BPP2658 of B. parapertussis of 48% (trembl|Q7W772(SRS)). 3 TMHs. no signal protein. Has PF04239;Protein of unknown function (DUF421);IPR007353 DUF421; Conserved hypothetical protein; hypothetical protein	complement(1987987..1988523)	Azoarcus sp. BH72	4607067
YP_933316.1	CDS	azo1812	NC_008702.1	1988694	1990121	D	Probable transcriptional regulatory protein,; Specificity unclear; transcriptional regulator	1988694..1990121	Azoarcus sp. BH72	4607068
YP_933317.1	CDS	azo1813	NC_008702.1	1990267	1990617	D	Hypothetical protein. Weak homology with hits.; hypothetical protein	1990267..1990617	Azoarcus sp. BH72	4607069
YP_933318.1	CDS	azo1814	NC_008702.1	1990819	1991112	D	Conserved hypothetical protein. Homology to ebD123 of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebD123(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	1990819..1991112	Azoarcus sp. BH72	4607070
YP_933319.1	CDS	azo1815	NC_008702.1	1991120	1991503	D	Hypothetical membrane protein. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. 2 TMHs; hypothetical protein	1991120..1991503	Azoarcus sp. BH72	4607071
YP_933320.1	CDS	azo1816	NC_008702.1	1991500	1991976	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted No signal peptide 2 TMHs; hypothetical protein	1991500..1991976	Azoarcus sp. BH72	4607072
YP_933321.1	CDS	azo1817	NC_008702.1	1992008	1995052	D	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembrane helices.; Conserved hypothetical protein; putative two-component hybrid sensor and regulator	1992008..1995052	Azoarcus sp. BH72	4607073
YP_933322.1	CDS	azo1818	NC_008702.1	1995107	1996027	D	Putative ribonuclease RNASE BN (RBN)Protein, 31% identity (44% similarity) to TrEMBL; Q8XPH6. Has PF03631; Ribonuclease BN-like family;IPR004664, RNase_BN;This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Family membership; exoribonuclease II	1995107..1996027	Azoarcus sp. BH72	4607074
YP_933323.1	CDS	azo1819	NC_008702.1	1996190	1997581	D	Hypothetical protein. Homology to dr0392 of D. radiodurans of 25% (trembl|Q9RXC3) Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. no signal peptide no TMHs; High confidence in function and specificity; hypothetical protein	1996190..1997581	Azoarcus sp. BH72	4607075
YP_933324.1	CDS	azo1820	NC_008702.1	1997651	1998100	D	Conserved hypothetical protein. Homology to BB2852 of B.bronchiseptica of 53% (tremble:Q7WIJ9). Has pfam05239, PRC, PRC-barrel domain. The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins conserved in all known euryarchaea are composed entirely of a single stand-alone copy of the domain. NO signal peptide reported to be present. No TMH reported to be present.; hypothetical protein	1997651..1998100	Azoarcus sp. BH72	4607076
YP_933325.1	CDS	azo1821	NC_008702.1	1998158	2000881	D	Conserved hypothetical membrane protein. Homology to ebA6882 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebA6882(KEGG)). Domian structure: 373 aa -599 aa AAA ATPase; 638 aa - 726 aa HATPase_c; 750 aa - 877 aa Rec InterPro: ABC transporter (IPR003439); AAA ATPase superfamily (IPR003593); ABC transporter transmembrane region (IPR001140); ATP/GTP-binding site motif A ((P-loop) (IPR001687); (Response regulator reciver (IPR001789); Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase (IPR003594) Pfam: ABC-transporter ABC transmembrane region; Response regulator reciver domain. no signal peptide. probable 5 TMHs; Conserved hypothetical protein; hypothetical protein	1998158..2000881	Azoarcus sp. BH72	4607077
YP_933326.1	CDS	azo1822	NC_008702.1	2000904	2001464	D	Conserved hypothetical protein. Signal peptide present.; hypothetical protein	2000904..2001464	Azoarcus sp. BH72	4607078
YP_933327.1	CDS	azo1823	NC_008702.1	2001475	2002209	D	Putative Mg(2+) transporter ATPase [attV], 58% identity (77% similarity) to TrEMBL;Q8UKG4, Q9WWC7. TrEMBBL;Q7W456(66% identity). Has PF02308;MgtC family;(IPR003416, MgtCSapB_transpt):The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known. No Signal peptide or TMH reported present.; Family membership; putative Mg(2+) transporter	2001475..2002209	Azoarcus sp. BH72	4607079
YP_933328.1	CDS	ygaD2	NC_008702.1	2002246	2002746	R	Protein ygaD. TREMBL:Q7W761: 58% identity, 68% similarity CinA is a DNA damage- or competence-inducible protein that is polycistronic with recA in a number of species. Several bacterial species have a protein consisting largely of the C-terminal domain of CinA but lacking the N-terminal domain. InterPro: Competence-damaged protein InterPro: IPR008136; CinA_C. Pfam: PF02464 cinA_cterm: competence/damage-inducible No Signal peptide (Signal P predicted) No transmembrane helices; Function unclear; CinA domain-containing protein	complement(2002246..2002746)	Azoarcus sp. BH72	4607080
YP_933329.1	CDS	azo1825	NC_008702.1	2002713	2003273	R	Conserved hypothetical membrane protein. Homology to smb20339 of S. meliloti of 30% (trembl|Q92WL4(SRS)). No domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2002713..2003273)	Azoarcus sp. BH72	4610176
YP_933330.1	CDS	azo1826	NC_008702.1	2003309	2004646	D	39%; NADH dehydrogenase	2003309..2004646	Azoarcus sp. BH72	4607081
YP_933331.1	CDS	azo1827	NC_008702.1	2004654	2005118	D	Conserved hypothetical membrane protein. Homology to CC2898 of Caulobacter crescentus of 56% (trembl|Q89WY3(SRS)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	2004654..2005118	Azoarcus sp. BH72	4607082
YP_933332.1	CDS	azo1828	NC_008702.1	2005129	2006316	R	Hypothetical secreted protein. No significant homology over the entire protein length with the data bank. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (IPR001834). Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain. signal peptide. no TMHs; hypothetical protein	complement(2005129..2006316)	Azoarcus sp. BH72	4607083
YP_933333.1	CDS	azo1829	NC_008702.1	2006232	2007008	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide. 1 TMHs; hypothetical protein	complement(2006232..2007008)	Azoarcus sp. BH72	4607084
YP_933334.1	CDS	azo1830	NC_008702.1	2007034	2009067	R	Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. ilvC: ketol-acid reductoisomerase; Function unclear; putative TonB-denpendent receptor	complement(2007034..2009067)	Azoarcus sp. BH72	4607085
YP_933335.1	CDS	mauG	NC_008702.1	2009546	2010928	D	Di-heme cytochrome c peroxidase MauG, required for the synthesis of the tryptophan tryptophylquinone (TTQ) prosthetic group of MADH in P.denitrificans . INVOLVED IN METHYLAMINE METABOLISM. ESSENTIAL FOR THE MATURATION OF THE BETA SUBUNIT OF MADH PRESUMABLY VIA A STEP IN THE BIOSYNTHESIS OF TRYPTOPHAN TRYPTOPHYLQUINONE (TTQ) THE COFACTOR OF MADH. urease_gam: urease gamma subunit; High confidence in function and specificity; putative cytochrome c551 peroxidase	2009546..2010928	Azoarcus sp. BH72	4607086
YP_933336.1	CDS	azo1832	NC_008702.1	2010939	2011565	D	Conserved hypothetical secreted protein. Homology ebA6930 of Azoarcus EbN1 of 31% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	2010939..2011565	Azoarcus sp. BH72	4609200
YP_933337.1	CDS	alkA	NC_008702.1	2011690	2012379	D	DNA-3-methyladenine glycosylase 1 (3-methyladenine DNA glycosidase 1) (3MEA DNA glycosylase 1). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE OR 7-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. CAN RELEASE ETHYLATED AND PROPYLATED BASES FROM DNA IN ADDITION TO 3-METHYLADENINE. TIGR00274: glucokinase regulator-related.; High confidence in function and specificity; DNA-3-methyladenine glycosylase II	2011690..2012379	Azoarcus sp. BH72	4607087
YP_933338.1	CDS	ndh2	NC_008702.1	2012480	2013760	R	Probable NADH dehydrogenase. Homology to ndh of P. fluorescens of 45% (trembl|Q9KGX09 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; NADH dehydrogenase	complement(2012480..2013760)	Azoarcus sp. BH72	4608302
YP_933339.1	CDS	azo1835	NC_008702.1	2013981	2014892	R	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	complement(2013981..2014892)	Azoarcus sp. BH72	4609349
YP_933340.1	CDS	azo1836	NC_008702.1	2015262	2016950	D	Hypothetical protein sharing 76% similarity(61% identity) with Hypothetical protein [Thauera aromatica]TrEMBl O87938. Has pfam06980, DUF1302 domain,Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.(IPR010727) No Signal peptide or TMH being reported to be present.; Function unclear; hypothetical protein	2015262..2016950	Azoarcus sp. BH72	4607088
YP_933341.1	CDS	azo1837	NC_008702.1	2016980	2018332	D	Conserved hypothetical secreed protein. Homology to PA3081 of P.aeruginosa of 40% (tremble:Q9HZC7). Has DUF1329 domain(PF07044,IPRO10752). Protein of unknown function (DUF1329):This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs. Signal present.; Conserved hypothetical protein; hypothetical protein	2016980..2018332	Azoarcus sp. BH72	4607089
YP_933342.1	CDS	azo1838	NC_008702.1	2018425	2019552	D	Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 46% (trembl|Q88I01). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear; hypothetical protein	2018425..2019552	Azoarcus sp. BH72	4607090
YP_933343.1	CDS	azo1839	NC_008702.1	2019552	2021942	D	Putative membrane protein MJ1562. TREMBL:Q88I00: 66% identity, 51% similarity The sterol-sensing domain (SSD) consists of approximately 180 amino acids organized into a cluster of five consecutive membrane-spanning domains and is found in proteins which have key roles in different aspects of cholesterol homeostasis or cholesterol-linked signalling such as sterol-regulated movement or the trafficking of specific cargoes. InterPro:IPR000731; SSD_5TM Found in :IPR003392: Patched family IPR004816: Hydroxymethylglutaryl-CoA reductase (NADPH Pfam:Patched:Patched family TIGRFAM:2A060602:transmembrane receptor Patch 2A0604s01: protein-export membrane pro TMHMM predicted 12 transmembrane helices; Family membership; transporter	2019552..2021942	Azoarcus sp. BH72	4607091
YP_933344.1	CDS	azo1840	NC_008702.1	2021961	2022410	D	Putative universal stress protein,; Conserved hypothetical protein; putative universal stress protein	2021961..2022410	Azoarcus sp. BH72	4607092
YP_933345.1	CDS	azo1841	NC_008702.1	2022415	2023890	D	Methyl-accepting chemotaxis protein,; Specificity unclear; methyl-accepting chemotaxis transducer	2022415..2023890	Azoarcus sp. BH72	4607093
YP_933346.1	CDS	lapR	NC_008702.1	2024002	2025687	D	Transcriptional regulatory protein lapR. In Pseudomonas sp. strain KL28 the genes, designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation. The lapR gene is transcribed independently and encodes a member of the XylR/DmpR positive transcriptional regulators. Similarity to SWISSPROT: sprot|XYLR_PSEPU (45% Pseudomonas putida, XylR) / TREMBL: trembl|Q7WYF6 (63% Pseudomonas strain KL28,LapR) InterPro: IPR002078 Sig54_interact. IPR004096 V4R. IPR003593 AAA_ATPase. IPR002197 HTH_Fis. Pfam: PF02954 HTH_8. PF00158 Sigma54_activat. PF02830 V4R. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; transcriptional regulator	2024002..2025687	Azoarcus sp. BH72	4607094
YP_933347.1	CDS	azo1843	NC_008702.1	2026337	2026654	D	plant type ferredoxin like protein cofactor: binds 1 2fe-2s cluster (by similarity). Pfam: fer2 2Fe-2S iron-sulfur cluster binding do; Function unclear; plant type ferredoxin like protein	2026337..2026654	Azoarcus sp. BH72	4609123
YP_933348.1	CDS	lapB1	NC_008702.1	2026691	2027626	D	In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation. Catechol 2,3-dioxygenase LapB,; High confidence in function and specificity; catechol 2,3-dioxygenase	2026691..2027626	Azoarcus sp. BH72	4607095
YP_933349.1	CDS	lapK	NC_008702.1	2027628	2027888	D	Phenol 2-monooxygenase p0 component,; High confidence in function and specificity; phenol 2-monooxygenase	2027628..2027888	Azoarcus sp. BH72	4609109
YP_933350.1	CDS	lapL	NC_008702.1	2027934	2028926	D	Phenol hydroxylase p1 protein. Catabolizes phenol and some of its methylated derivates. P1 is required for growth on phenol and for in vitro phenol hydroxylase activity. Similar to SWISSPROT: sprot|DMPL_PSESP (52% Pseudomonas sp. (strain CF600), DmpL) / TREMBL: trembl|Q7WYF3 (67% Pseudomonas sp. KL28, LapL) InterPro: IPR003430 Phenol_Hydrox. Pfam: PF02332 Methane/Phenol/Toluene Hydroxylase. Part of the lap operon: In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. The lap genes are located in a 13.2 kb region with 14 ORFs in the order lapRBKLMNOPCEHIFG and with the same transcriptional orientation.; High confidence in function and specificity; phenol 2-monooxygenase subunit p1	2027934..2028926	Azoarcus sp. BH72	4609117
YP_933351.1	CDS	lapM	NC_008702.1	2028935	2029204	D	Phenol 2-monooxygenase p2 component,; High confidence in function and specificity; phenol 2-monooxygenase subunit p2	2028935..2029204	Azoarcus sp. BH72	4609118
YP_933352.1	CDS	lapN	NC_008702.1	2029221	2030738	D	Phenol 2-monooxygenase p3 component,; High confidence in function and specificity; phenol 2-monooxygenase subunit p3	2029221..2030738	Azoarcus sp. BH72	4609119
YP_933353.1	CDS	lapO	NC_008702.1	2030817	2031173	D	Phenol 2-monooxygenase p4 component,; High confidence in function and specificity; phenol 2-monooxygenase subunit p4	2030817..2031173	Azoarcus sp. BH72	4609120
YP_933354.1	CDS	lapP	NC_008702.1	2031229	2032290	D	Phenol hydroxylase P5 protein (EC 1.14.13.7) (Phenol 2-monooxygenase P5 component). Probable electron transfer from NADPH via FAD and the 2Fe-2S center to the oxygenase activity site of the enzyme.; High confidence in function and specificity; phenol 2-monooxygenase	2031229..2032290	Azoarcus sp. BH72	4609121
YP_933355.1	CDS	azo1851	NC_008702.1	2032562	2033650	R	Conserved hypothetical protein. Homology to an orf of Vibrio vulnificus of 41% (gi|51242695|gb|AAT99285.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2032562..2033650)	Azoarcus sp. BH72	4609122
YP_933356.1	CDS	lapC	NC_008702.1	2034874	2036334	D	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase,; High confidence in function and specificity; 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase	2034874..2036334	Azoarcus sp. BH72	4607096
YP_933357.1	CDS	lapE	NC_008702.1	2036713	2037510	D	Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate, involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. Belongs to the todj/xyli/xylj/hpcg family, TREMBL:Q93JW5 (62% identity); SWISSPROT:P23107 (58% identity). Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity; 2-oxopent-4-enoate hydratase	2036713..2037510	Azoarcus sp. BH72	4609111
YP_933358.1	CDS	lapH	NC_008702.1	2037507	2038310	D	Conversion of 4-oxalocrotonate into 2-oxopent-4-enoate, involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. Belongs to the todJ/xylI/xylJ/hpcG family, TREMBL:Q8RQD3 (56% identity); SWISSPROT:P23107. Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity; 4-oxalocrotonate decarboxylase	2037507..2038310	Azoarcus sp. BH72	4609112
YP_933359.1	CDS	lapI	NC_008702.1	2038330	2038551	D	4-oxalocrotonate isomerase,; High confidence in function and specificity; oxaloacetate tautomerase	2038330..2038551	Azoarcus sp. BH72	4609115
YP_933360.1	CDS	lapF	NC_008702.1	2038548	2039462	D	catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase	2038548..2039462	Azoarcus sp. BH72	4609116
YP_933361.1	CDS	lapG	NC_008702.1	2039462	2040505	D	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase	2039462..2040505	Azoarcus sp. BH72	4609113
YP_933362.1	CDS	xylE	NC_008702.1	2041184	2042116	D	Catechol 2,3-dioxygenase XylE catalyzes the ring cleavage of catechol and some substituted catechols. Similar to pir|JE0112 (52%), to trembl|Q45459 (48%)and to sprot|XYE2_PSEPU (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD000977): Extradiol ring-cleavage dioxygenase; Specificity unclear; catechol 2,3-dioxygenase	2041184..2042116	Azoarcus sp. BH72	4609114
YP_933363.1	CDS	azo1859	NC_008702.1	2042142	2042897	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q82N83 (22% identity); TREMBL:Q9F8V0 (21% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	2042142..2042897	Azoarcus sp. BH72	4610133
YP_933364.1	CDS	azo1860	NC_008702.1	2042908	2043327	D	Putative tautomerase Weak Homology with others similar proteins. Has 2 copies of PF01361, Tautomerase enzyme;IPR004370, Taut;This family includes the enzyme 4-oxalocrotonate tautomerase Q01468 that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate.; putative tautomerase	2042908..2043327	Azoarcus sp. BH72	4607097
YP_933365.1	CDS	azo1861	NC_008702.1	2043439	2044947	R	Hypothetical protein. No homology of the entire protein to the data base. Has (IPR002790)PF01936;Protein of unknown function DUF88; This highly conserved bacterial protein has no known function. The alignment contains many conserved aspartates, suggesting an enzymatic function such as an endonuclease or glycosyl hydrolase (Bateman A pers. obs). No Signal peptide or TMH present.; hypothetical protein	complement(2043439..2044947)	Azoarcus sp. BH72	4607098
YP_933366.1	CDS	rluA2	NC_008702.1	2045147	2045857	D	Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.; Family membership; pseudouridine synthase A	2045147..2045857	Azoarcus sp. BH72	4607099
YP_933367.1	CDS	azo1863	NC_008702.1	2046178	2047254	D	Integrase. INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION WITH EXCISIONASE INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE PROPHAGE FROM THE HOST GENOME.; Specificity unclear; phage integrase family site specific recombinase	2046178..2047254	Azoarcus sp. BH72	4610007
YP_933368.1	CDS	azo1864	NC_008702.1	2047997	2048656	D	Hypothetical protein , 27% identity to TrEMBL;Q84EQ6. No domains, repeats, motifs or features present.; hypothetical protein	2047997..2048656	Azoarcus sp. BH72	4607100
YP_933369.1	CDS	azo1865	NC_008702.1	2048746	2049024	D	Hypothetical protein. No matches in the database. No domains, repeats, motifs or features present.; hypothetical protein	2048746..2049024	Azoarcus sp. BH72	4607101
YP_933370.1	CDS	azo1866	NC_008702.1	2049041	2049337	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2049041..2049337	Azoarcus sp. BH72	4607102
YP_933371.1	CDS	azo1867	NC_008702.1	2049341	2049763	D	Hypothetical protein. Very weak homology with hits in the database. No domains, repeats, motifs or features present.; hypothetical protein	2049341..2049763	Azoarcus sp. BH72	4607103
YP_933372.1	CDS	azo1868	NC_008702.1	2050193	2050453	D	Hypothetical protein, very weak homology with hits in the Database. No Motifs,domains, or Signal peptide present.; hypothetical protein	2050193..2050453	Azoarcus sp. BH72	4607104
YP_933373.1	CDS	azo1869	NC_008702.1	2050453	2050995	D	Putative Hypothetical protein. Very weak homology with hits in the Database. No signficant domains, motifs or Signal Peptide present.; hypothetical protein	2050453..2050995	Azoarcus sp. BH72	4607105
YP_933374.1	CDS	azo1870	NC_008702.1	2050956	2052833	D	Putative protease encoded ATP-dependent Clp protease family protein similar(30 Identity,45% similarity in function) to TrEMBL:Q8X866. IPR001907. Has pfam00574,CLP_protease, Clp protease. The Clp protease has an active site catalytic triad. In E. coli Clp protease, ser-111,his-136 and asp-185 form the catalytic triad. One member has lost all of these active site residues and is therefore inactive. Some members contain one or two large insertions. Peptidase family S49 domain present. Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). PF00574;CLP_protease PR00127;CLPPROTEASEP PS00381;CLP_PROTEASE_SER PS00382;CLP_PROTEASE_HIS TIGR00493;clpP No Signal peptide or TMH being reported as present.; High confidence in function and specificity; endopeptidase Clp	2050956..2052833	Azoarcus sp. BH72	4607106
YP_933375.1	CDS	azo1871	NC_008702.1	2052959	2053276	D	hypothetical protein	2052959..2053276	Azoarcus sp. BH72	4607107
YP_933376.1	CDS	azo1872	NC_008702.1	2053263	2055575	D	Hypothetical phage tail tape measure protein. Controls phage tail length no signal peptide. no TMH; phage tail tape measure protein	2053263..2055575	Azoarcus sp. BH72	4607108
YP_933377.1	CDS	azo1873	NC_008702.1	2055575	2056312	D	Hypothetical protein, 26% Identity to TrEMBL;Q9PFZ1. No domains, repeats, motifs or features could be predicted above threshold.; hypothetical protein	2055575..2056312	Azoarcus sp. BH72	4607109
YP_933378.1	CDS	rmlC	NC_008702.1	2056922	2057467	R	dTDP-4-dehydrorhamnose 35-epimerase (EC 5.1.3.13) (dTDP-4-keto-6- deoxyglucose 35-epimerase) (dTDP-L-rhamnose synthetase). InterPro: dTDP-4-dehydrorhamnose 35-epimerase; High confidence in function and specificity; dTDP-4-dehydrorhamnose 3,5-epimerase	complement(2056922..2057467)	Azoarcus sp. BH72	4607110
YP_933379.1	CDS	rmlA	NC_008702.1	2057467	2058351	R	Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase).; High confidence in function and specificity; glucose-1-phosphate thymidylyltransferase	complement(2057467..2058351)	Azoarcus sp. BH72	4609737
YP_933380.1	CDS	azo1876	NC_008702.1	2058363	2059253	R	Region start changed from 2059335 to 2059254 (-81 bases); dTDP-4-dehydrorhamnose reductase	complement(2058363..2059253)	Azoarcus sp. BH72	4609735
YP_933381.1	CDS	rmlB	NC_008702.1	2059250	2060326	R	dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; dTDP-glucose 4,6-dehydratase	complement(2059250..2060326)	Azoarcus sp. BH72	4607111
YP_933382.1	CDS	azo1878	NC_008702.1	2060555	2061478	D	Conserved hypothetical secreted protein. Homology to pp4172 of P. putida of 33% (trembl|Q88FC6). Pfam: DUF534 This is a family of putative secreted proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2060555..2061478	Azoarcus sp. BH72	4609736
YP_933383.1	CDS	azo1879	NC_008702.1	2061475	2063547	D	Conserved hypothetical signaling protein. Homology to Daro03001110 of Dechloromonas aromatica of 33% (gi|46141071|ref|ZP_00203851.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00563 EAL domain. PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 3 transmembrane helices.; Conserved hypothetical protein; putative signaling protein	2061475..2063547	Azoarcus sp. BH72	4607112
YP_933384.1	CDS	azo1880	NC_008702.1	2063554	2064687	R	Conserved hypothetical secreted protein. TREMBL:O86370 (36% identity); TREMBL:Q7U0W8 (36% identity). No domains predicted. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(2063554..2064687)	Azoarcus sp. BH72	4607113
YP_933385.1	CDS	azo1881	NC_008702.1	2064687	2067200	R	Similar to TREMBL:Q82US4 (29% identity). Pfam (DUF214): Predicted permease. TMHMM predicting 10 transmembrane helices.; Specificity unclear; ABC transporter permease	complement(2064687..2067200)	Azoarcus sp. BH72	4607114
YP_933386.1	CDS	azo1882	NC_008702.1	2067197	2067874	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q89X55 (42% identity); SWISSPROT:P31219 (40% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transporter.; Family membership; ABC transporter ATP-binding protein	complement(2067197..2067874)	Azoarcus sp. BH72	4607115
YP_933387.1	CDS	crtB1	NC_008702.1	2067967	2068812	D	Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 30% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership; putative phytoene synthase	2067967..2068812	Azoarcus sp. BH72	4607116
YP_933388.1	CDS	crtB2	NC_008702.1	2068913	2069746	D	Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 35% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership; putative phytoene synthase	2068913..2069746	Azoarcus sp. BH72	4608534
YP_933389.1	CDS	azo1885	NC_008702.1	2069751	2071058	D	Putative oxidoreductase precursor, 27% identity (38% similarity) to TrEMBL;Q6N3F3. TrEMBL;Q9RI54. Has PF00070;Pyridine nucleotide-disulphide oxidoreductase; IPR001327 FAD_pyr_redox:This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. Has PF01593,Flavin containing amine oxidoreductase;(IPR002937,Amino_oxidase):This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters,neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Has PF01494, FAD binding domain;(IPR002938 Moxy_FAD_binding);This domain is involved in FAD binding in a number of enzymes.; Family membership; putative oxidoreductase	2069751..2071058	Azoarcus sp. BH72	4608535
YP_933390.1	CDS	azo1886	NC_008702.1	2071071	2072195	R	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl|Q8XXV5). no domain predicted. no signal peptide. no TMHs; hypothetical protein	complement(2071071..2072195)	Azoarcus sp. BH72	4607117
YP_933391.1	CDS	azo1887	NC_008702.1	2072225	2073010	R	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583 ;Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; hypothetical protein	complement(2072225..2073010)	Azoarcus sp. BH72	4607118
YP_933392.1	CDS	bioA	NC_008702.1	2073125	2074477	D	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; adenosylmethionine-8-amino-7-oxononanoate aminotransferase	2073125..2074477	Azoarcus sp. BH72	4607119
YP_933393.1	CDS	bioF	NC_008702.1	2074477	2075649	D	8-amino-7-oxononanoate synthase (EC 2.3.1.47) (AONS) (8-amino-7- ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase). InterPro: Aminotransferases class-I bioF: 8-amino-7-oxononanoate synthase; High confidence in function and specificity; 8-amino-7-oxononanoate synthase	2074477..2075649	Azoarcus sp. BH72	4608389
YP_933394.1	CDS	bioH	NC_008702.1	2075642	2076406	D	BioH protein.Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). Seems to be implicated in the early steps of biotin biosynthesis.; Function unclear; BioH protein	2075642..2076406	Azoarcus sp. BH72	4608394
YP_933395.1	CDS	bioC1	NC_008702.1	2076399	2077193	D	Biotin synthesis protein bioC. bioc is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin.; Specificity unclear; biotin synthesis protein	2076399..2077193	Azoarcus sp. BH72	4608395
YP_933396.1	CDS	bioD	NC_008702.1	2077190	2077876	D	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase	2077190..2077876	Azoarcus sp. BH72	4608391
YP_933397.1	CDS	azo1893	NC_008702.1	2077881	2078672	R	Region start changed from 2079087 to 2078673 (-414 bases); RNA methyltransferase	complement(2077881..2078672)	Azoarcus sp. BH72	4608393
YP_933398.1	CDS	azo1894	NC_008702.1	2078681	2079136	R	Conserved hypothetical membrane protein. Homology to PA1044 of P. aeruginosa of 44% (trembl|Q9I4T0). No domains predicted. Signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2078681..2079136)	Azoarcus sp. BH72	4607120
YP_933399.1	CDS	rnhB	NC_008702.1	2079133	2079747	R	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII	complement(2079133..2079747)	Azoarcus sp. BH72	4607121
YP_933400.1	CDS	lpxB	NC_008702.1	2079720	2080895	R	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase	complement(2079720..2080895)	Azoarcus sp. BH72	4609754
YP_933401.1	CDS	lpxA	NC_008702.1	2080900	2081670	R	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase	complement(2080900..2081670)	Azoarcus sp. BH72	4609175
YP_933402.1	CDS	fabZ	NC_008702.1	2081667	2082104	R	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase	complement(2081667..2082104)	Azoarcus sp. BH72	4609174
YP_933403.1	CDS	lpxD	NC_008702.1	2082110	2083135	R	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	complement(2082110..2083135)	Azoarcus sp. BH72	4608716
YP_933404.1	CDS	ompH	NC_008702.1	2083149	2083649	R	Probable outer membrane protein. Homology to ompH of Y. enterocolitica of 30% (sprot|OMPH_YEREN). Pfam: outer membrane protein (OmpH-like) signal peptide no TMHs; High confidence in function and specificity; outer membrane protein	complement(2083149..2083649)	Azoarcus sp. BH72	4609177
YP_933405.1	CDS	oma	NC_008702.1	2083683	2085962	R	InterPro: Bacterial surface antigen (D15); Function unclear; outer membrane protein	complement(2083683..2085962)	Azoarcus sp. BH72	4609445
YP_933406.1	CDS	azo1902	NC_008702.1	2086001	2087365	R	Conserved hypothetical membrane-associated zinc metalloprotease. Homology to ne1711 of N. europaea of 51% (trembl|Q82U02). Tigrfam: TIGR00054: membrane-associated zinc metalloprotease. Pfam: PDZ domain (Also known as DHR or GLGF). no signal peptide. 4 TMHs; Family membership; membrane-associated zinc metalloprotease	complement(2086001..2087365)	Azoarcus sp. BH72	4609441
YP_933407.1	CDS	dxr	NC_008702.1	2087365	2088564	R	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase	complement(2087365..2088564)	Azoarcus sp. BH72	4607122
YP_933408.1	CDS	cdsA	NC_008702.1	2088581	2089405	R	Phosphatidate cytidylyltransferase :- catalytic activity ctp + phosphatidate = diphosphate + cdp-diacylglycerol. pathway :-phospholipid biosynthesis. Entry name:- CDSA_ECOLI Primary accession number :- P06466 InterPro:- IPR000374; PC_trans. Identities = 89/252 (35%) Pfam PF01148; CTP_transf_1; 1. Number of predicted TMHs: 7 Prediction: Signal peptide Signal peptide probability: 1.0; Family membership; putative phosphatidate cytidylyltransferase	complement(2088581..2089405)	Azoarcus sp. BH72	4608658
YP_933409.1	CDS	uppS	NC_008702.1	2089398	2090198	R	Undecaprenyl pyrophosphate synthetase :- Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of the carrier lipid for peptidoglycan synthesis (By similarity). Identities = 124/228 (54%) Entry name SWISSPROT:UPPS_ECOLI Prim. accession # P60472 InterPro :- IPR001441; UPP_synth. Pfam:- PF01255; UPP_synthetase; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.0; Family membership; undecaprenyl pyrophosphate synthetase	complement(2089398..2090198)	Azoarcus sp. BH72	4608461
YP_933410.1	CDS	frr	NC_008702.1	2090246	2090803	R	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor	complement(2090246..2090803)	Azoarcus sp. BH72	4610070
YP_933411.1	CDS	pyrH	NC_008702.1	2090814	2091530	R	Catalyzes the phosphorylation of UMP to UDP; uridylate kinase	complement(2090814..2091530)	Azoarcus sp. BH72	4608830
YP_933412.1	CDS	tsf	NC_008702.1	2091541	2092434	R	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts	complement(2091541..2092434)	Azoarcus sp. BH72	4609674
YP_933413.1	CDS	rpsB	NC_008702.1	2092546	2093301	R	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2	complement(2092546..2093301)	Azoarcus sp. BH72	4610045
YP_933414.1	CDS	map	NC_008702.1	2093581	2094399	D	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase	2093581..2094399	Azoarcus sp. BH72	4607123
YP_933415.1	CDS	glnD	NC_008702.1	2094419	2097004	D	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase	2094419..2097004	Azoarcus sp. BH72	4609194
YP_933416.1	CDS	azo1912	NC_008702.1	2097065	2097700	R	Conserved hypothetical membrane protein. Homology to RPA0231 of Rhodopseudomonas palustris of 39% (trembl|Q6ND78). Has PF03350,(IPR005134) Uncharacterized protein family, UPF0114: This conserved hypothetical protein family with four predicted transmembrane regions is found in E. coli, Haemophilus influenzae, and Helicobacter pylori, among completed genomes. No signal peptide. 3 TMHs; hypothetical protein	complement(2097065..2097700)	Azoarcus sp. BH72	4608896
YP_933417.1	CDS	azo1913	NC_008702.1	2097850	2099463	D	Conserved hypothetical protein. Homology to pp1134 of P. putida of 77% (trembl|Q88NS1). Pfam: Phytoene dehydrogenase related enzyme. no signal peptide. no TMHs; hypothetical protein	2097850..2099463	Azoarcus sp. BH72	4607124
YP_933418.1	CDS	dctD2	NC_008702.1	2099467	2100810	R	C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity; transcriptional regulator	complement(2099467..2100810)	Azoarcus sp. BH72	4607125
YP_933419.1	CDS	dctB2	NC_008702.1	2100821	2102704	R	C4-dicarboxylate transport sensor protein,; High confidence in function and specificity; sensor histidine kinase	complement(2100821..2102704)	Azoarcus sp. BH72	4608596
YP_933420.1	CDS	azo1916	NC_008702.1	2102656	2103072	R	Conserved hypothetical secreted protein. Homology to blr1303 of B. japonicum of 38% (trembl|Q89UV6(SRS)) No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(2102656..2103072)	Azoarcus sp. BH72	4608594
YP_933421.1	CDS	azo1917	NC_008702.1	2103072	2105108	R	Conserved hypothetical membrane protein. Homology to so0455 of S. oneidensis of 65% (trembl|Q8EJK8). Tigrfam: dctM: TRAP dicarboxylate transporter-DctM subunit. Pfam: TRAP C4-dicarboxylate transport (Dct) system permease DctM subunit. This domain represents a conserved region located towards the N terminus of the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. no signal peptide. 17 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2103072..2105108)	Azoarcus sp. BH72	4607126
YP_933422.1	CDS	azo1918	NC_008702.1	2105234	2106184	R	Conserved hypothetical secreted protein. Homology to pp3954 pf P. putida of 64% (trembl|Q88FX3). no domains predicted. singal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(2105234..2106184)	Azoarcus sp. BH72	4607127
YP_933423.1	CDS	azo1919	NC_008702.1	2106499	2107608	D	Hypothetical protein MG039 homolog (D09_orf384). D-amino acid oxidase (EC: 1.4.3.3) (DAMOX or DAO) is an FAD flavoenzyme that catalyzes the oxidation of neutral and basic D-amino acids into their corresponding keto acids. DAOs have been characterized and sequenced in fungi and vertebrates where they are known to be located in the peroxisomes. InterPro: D-amino acid oxidase Putative conserved exported protein. TREMBL:Q7WG75: 55% identity,65% similarity. TREMBLnew:CAE29609. Pfam:NAD binding FAD dependent oxidoreductase. TIGRFAM:UDP-GALP mutase. Signal P predicted signal peptide and TMHMM predicted transmembrane helices. gidA: glucose-inhibited division prot; Specificity unclear; oxidoreductase	2106499..2107608	Azoarcus sp. BH72	4607128
YP_933424.1	CDS	gabD2	NC_008702.1	2107621	2109078	R	Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of P. aeruginosa of 62% (trembl|Q9RBF6) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity; succinate semialdehyde dehydrogenase	complement(2107621..2109078)	Azoarcus sp. BH72	4607129
YP_933425.1	CDS	etfA2	NC_008702.1	2109292	2110215	R	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 66% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity; electron transfer flavoprotein subunit alpha	complement(2109292..2110215)	Azoarcus sp. BH72	4608852
YP_933426.1	CDS	etfB2	NC_008702.1	2110306	2111055	R	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity; electron transfer flavoprotein subunit beta	complement(2110306..2111055)	Azoarcus sp. BH72	4608679
YP_933427.1	CDS	azo1923	NC_008702.1	2111082	2112305	R	Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs; hypothetical protein	complement(2111082..2112305)	Azoarcus sp. BH72	4608683
YP_933428.1	CDS	gcdH1	NC_008702.1	2112858	2114045	R	CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q98HG5 Prim. accession # Q98HG5 Identities = 253/397 (63%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; glutaryl-CoA dehydrogenase	complement(2112858..2114045)	Azoarcus sp. BH72	4607130
YP_933429.1	CDS	azo1925	NC_008702.1	2114231	2115175	D	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	2114231..2115175	Azoarcus sp. BH72	4608864
YP_933430.1	CDS	azo1926	NC_008702.1	2115279	2116043	D	Hypothetical protein. no homology over the entire protein. no domain structure no signal peptide no TMHs; hypothetical protein	2115279..2116043	Azoarcus sp. BH72	4607131
YP_933431.1	CDS	azo1927	NC_008702.1	2116100	2116894	R	Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or3)-enoyl-CoA + H2O. Entry name TREMBL:Q7VU52 Prim. accession # Q7VU52 Identities = 124/266 (46%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; High confidence in function and specificity; enoyl-CoA hydratase	complement(2116100..2116894)	Azoarcus sp. BH72	4607132
YP_933432.1	CDS	abmE	NC_008702.1	2116903	2117298	R	Conserved hypothetical protein. Homology to orf5 of Azoarcus evansii of 78% (tremble:Q93FB4). Pfam: Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. No signal peptide. No TMHs; hypothetical protein	complement(2116903..2117298)	Azoarcus sp. BH72	4607133
YP_933433.1	CDS	azo1929	NC_008702.1	2117291	2117746	R	TREMBL:Q89PR6: 50% identity; 71% similarity Probable 4-hydroxybenzoyl-CoA thioesterase . InterPro:IPR008272; 4HBcoA_thiost_AS Pfam:4HBT:4-hydroxybenzoyl-CoA thioesterase TIGR00051: conserved hypothetical protein No transmembrane helices; Function unclear; 4-hydroxybenzoyl CoA thioesterase	complement(2117291..2117746)	Azoarcus sp. BH72	4608251
YP_933434.1	CDS	gcdH2	NC_008702.1	2117761	2118942	R	Glutaryl-CoA dehydrogenase mitochondrial precursor CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q88RH2 Prim. accession # Q88RH2 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number of predicted TMHs: 0; Family membership; glutaryl-CoA dehydrogenase	complement(2117761..2118942)	Azoarcus sp. BH72	4607134
YP_933435.1	CDS	abmD	NC_008702.1	2118989	2120140	R	Catalysis of the reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q98BT9 Prim. accession # Q98BT9 InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. Number of predicted TMHs: 0; Family membership; putative acyl-CoA dehydrogenase	complement(2118989..2120140)	Azoarcus sp. BH72	4608865
YP_933436.1	CDS	abmC	NC_008702.1	2120148	2120993	R	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	complement(2120148..2120993)	Azoarcus sp. BH72	4608250
YP_933437.1	CDS	abmB	NC_008702.1	2121433	2122242	R	Probable beta-hydroxyacyl-CoA dehydrogenase. Homology to abmB of A. evansii of 79%. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. No signal peptide. No TMHs.; Specificity unclear; beta-hydroxyacyl-CoA dehydrogenase	complement(2121433..2122242)	Azoarcus sp. BH72	4608249
YP_933438.1	CDS	abmA	NC_008702.1	2122523	2124838	R	catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; salicylyl-CoA 5-hydroxylase	complement(2122523..2124838)	Azoarcus sp. BH72	4608248
YP_933439.1	CDS	azo1935	NC_008702.1	2124973	2125479	R	Putative MarR-family transcriptional regulator,; Family membership; MarR family transcriptional regulator	complement(2124973..2125479)	Azoarcus sp. BH72	4608247
YP_933440.1	CDS	azo1936	NC_008702.1	2125695	2126702	D	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	2125695..2126702	Azoarcus sp. BH72	4607135
YP_933441.1	CDS	azo1937	NC_008702.1	2126825	2127613	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q9AQN5 (39% identity); TREMBL:Q987X7 (35% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short chain dehydrogenase	2126825..2127613	Azoarcus sp. BH72	4607136
YP_933442.1	CDS	styA	NC_008702.1	2127668	2128966	D	Putative styrene monooxygenase. Homology to styA of P. fluorescens of 25% (TREMBL:O06834) Encode a styrene monooxygenase responsible for the transformation of styrene to epoxystyrene Pfam: FAD binding domain no signal peptide no TMHs; Family membership; putative styrene monooxygenase	2127668..2128966	Azoarcus sp. BH72	4607137
YP_933443.1	CDS	nmoB	NC_008702.1	2129059	2129544	D	Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q93NA5:48% identity, 62% similarity InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam:PF01613; Flavin_Reduct Non-secretory protein with low signal peptide probability (0.002) Absence of transmembrane helices; High confidence in function and specificity; monooxygenase component B	2129059..2129544	Azoarcus sp. BH72	4609902
YP_933444.1	CDS	azo1940	NC_008702.1	2129896	2130807	R	Conserved hypothetical membrane protein. Homology to PP4294 of P. putida of 67% (trembl|Q88F06). Has PF05661, Protein of unknown function (DUF808);IPR008526;This family consists of several bacterial proteins of unknown function. no signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2129896..2130807)	Azoarcus sp. BH72	4609385
YP_933445.1	CDS	gdhAlpha2	NC_008702.1	2130993	2132576	R	Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 28% (trembl|Q8GQE7). InterPro: NAD binding site (IPR000205); UBA/THIF-type NAD/FAD binding fold (IPR000594), $Fe-4s ferredoxin, ion-sulfur binding domain (IPR001450) Pfam: GMC oxidoreductase no signal peptide no TMHs gid: gid protein; Function unclear; putative glucose dehydrogenase subunit alpha	complement(2130993..2132576)	Azoarcus sp. BH72	4607138
YP_933446.1	CDS	azo1942	NC_008702.1	2132573	2133175	R	Hypothetical secreted protein. No good homology with hits in the database. No domains predicted. Signal peptide present. No TMHs; hypothetical protein	complement(2132573..2133175)	Azoarcus sp. BH72	4608874
YP_933447.1	CDS	hpaC	NC_008702.1	2133386	2133904	R	Putative flavin:NADH reductase ycdH (EC 1.6.8.-). Catalyzes the reduction of free flavins (FMN FAD and riboflavin) by NADH (By similarity). TREMBL:Q8RLG2: 41% identity, 60% similarity InterPro: Flavin reductase-like domain InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam PF01613; Flavin_Reduct gmhA: phosphoheptose isomerase No signal peptide Absence of transmembrane helices; Function unclear; HPA reductase	complement(2133386..2133904)	Azoarcus sp. BH72	4607139
YP_933448.1	CDS	azo1944	NC_008702.1	2133901	2135031	R	Conserved hypothetical protein. Homology to mll3445) of M. loti of 71% (trembl|Q98G8). InterPro: Bacterial luciferase (IPR002103). Pfam: Luciferase-like monooxygenase. no signal peptide. no TMHS; hypothetical protein	complement(2133901..2135031)	Azoarcus sp. BH72	4609024
YP_933449.1	CDS	azo1945	NC_008702.1	2135167	2136183	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(2135167..2136183)	Azoarcus sp. BH72	4607140
YP_933450.1	CDS	padB	NC_008702.1	2136465	2139191	D	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padB of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA5393(KEGG)). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655). Pfam: Molypdopterin oxidoreductase; Molydopterin dinucleotide binding domain. no signal peptide. no TMHs; Function unclear; phenylacetyl-CoA:acceptor oxidoreductase	2136465..2139191	Azoarcus sp. BH72	4607141
YP_933451.1	CDS	padC	NC_008702.1	2139188	2139835	D	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padC of A. evansiin of 61% (trembl|Q8L3B5). Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes (By similarity). Pfam: 4Fe-4S binding domain. Tigrfam: napF: ferredoxin-type protein NapF. no signal peptide. no TMHs; Family membership; phenylacetyl-CoA:acceptor oxidoreductase	2139188..2139835	Azoarcus sp. BH72	4609488
YP_933452.1	CDS	padD	NC_008702.1	2139832	2140698	D	Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padD of A. evansii of 43% (trembl|Q8L3B4(SRS) Pfam: DMSO reductase anchor subunit (DmsC) The terminal electron transfer enzyme Me2SO reductase of Escherichia coli is a heterotrimeric enzyme composed of a membrane extrinsic catalytic dimer (DmsAB) and a membrane intrinsic polytopic anchor subunit (DmsC). no signal peptide. 8 TMHs; Family membership; phenylacetyl-CoA:acceptor oxidoreductase	2139832..2140698	Azoarcus sp. BH72	4609489
YP_933453.1	CDS	azo1949	NC_008702.1	2140807	2141832	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(2140807..2141832)	Azoarcus sp. BH72	4609490
YP_933454.1	CDS	azo1950	NC_008702.1	2142429	2143481	D	Conserved hypothetical membrane protein. Homology to Daro03003315 of Dechloromonas aromatica of 48% (gi|53729651|ref|ZP_00348492.1|(NBCI ENTREZ)). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. no singal peptide. 1 TMHs; hypothetical protein	2142429..2143481	Azoarcus sp. BH72	4607142
YP_933455.1	CDS	azo1951	NC_008702.1	2143526	2145898	D	Probable Putative membrane protein MJ1562. TREMBL:Q8G9A8:32% identity, 52% similarity InterPro:IPR000873; AMP-bind. IPR002114; HPr_SerP_S Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide present (Signal P predicted) TMH's 10 (TMHMM predicted); Family membership; RND superfamily exporter	2143526..2145898	Azoarcus sp. BH72	4607143
YP_933456.1	CDS	azo1952	NC_008702.1	2145954	2147552	D	Conserved hypothetical secreted protein. Homology to Daro03003313 of Dechloromonas aromatica of 60% (gi|53729649|ref|ZP_00149978.2|(NBCI ENTREZ)). Has PF06980, Protein of unknown function (DUF1302);IPR010727,DUF1302;This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMHs; Conserved hypothetical protein; hypothetical protein	2145954..2147552	Azoarcus sp. BH72	4607144
YP_933457.1	CDS	azo1953	NC_008702.1	2147569	2148837	D	Conserved hypothetical secreted protein. Homology to Raeut03000741 of Ralstonia eutropha of 45% (gi|46131405|ref|ZP_00169583.2|(NBCI ENTREZ)). Pfam: Protein of unknown function (DUF1329). This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	2147569..2148837	Azoarcus sp. BH72	4607145
YP_933458.1	CDS	azo1954	NC_008702.1	2149426	2150184	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	complement(2149426..2150184)	Azoarcus sp. BH72	4607146
YP_933459.1	CDS	tms	NC_008702.1	2150473	2151930	R	catalyzes the formation of indole-3-acetic acid from indole-3-acetamide; indole acetimide hydrolase	complement(2150473..2151930)	Azoarcus sp. BH72	4607147
YP_933460.1	CDS	amiD	NC_008702.1	2151974	2153371	R	Putative amidase amiD; Family membership; amidase	complement(2151974..2153371)	Azoarcus sp. BH72	4609954
YP_933461.1	CDS	mhpC	NC_008702.1	2153368	2154240	R	TREMBLNEW:47357: 69% identity, 80% similarity. 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate hydrolase. The alpha/beta hydrolase fold [1] is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices Pfam: Ndr family. TIGR00148: conserved hypothetical protein; High confidence in function and specificity; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase	complement(2153368..2154240)	Azoarcus sp. BH72	4608310
YP_933462.1	CDS	azo1958	NC_008702.1	2154237	2154995	R	Putative Hydantoin racemase,28% Identity toTrEMBL;Q7NTB3,Q885G0,Q6YNI1. SProt;Q00924. Has PF01177,Asp/Glu/Hydantoin racemase;IPR001920, Asp/Glu_race; This family contains aspartate racemase, glutamate racemase,hydantoin racemase and arylmalonate decarboxylase. Aspartate racemase (EC: 5.1.1.13) and glutamate racemase (EC: 5.1.1.3) are two evolutionary related bacterial enzymes that do not seem to require a cofactor for their activity . Glutamate racemase, which interconverts L-glutamate into D-glutamate, is required for the biosynthesis of peptidoglycan and some peptide-based antibiotics such as gramicidin S. In addition to characterized aspartate and glutamate racemases, this family also includes a hypothetical protein from Erwinia carotovora and one from Escherichia coli (ygeA).Two conserved cysteines are present in the sequence of these enzymes. They are expected to play a role in catalytic activity by acting as bases in proton abstraction from the substrate.; putative Hydantoin racemase	complement(2154237..2154995)	Azoarcus sp. BH72	4609219
YP_933463.1	CDS	azo1959	NC_008702.1	2155368	2156693	R	Hypothetical protein SignalP reporting Non-secretory protein.; hypothetical protein	complement(2155368..2156693)	Azoarcus sp. BH72	4607148
YP_933464.1	CDS	oxoR	NC_008702.1	2156716	2157738	R	Reductase component OxoR, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation.; High confidence in function and specificity; putative 2-oxo-1 2-dihydroquinoline 8-monooxygenase reductase subunit	complement(2156716..2157738)	Azoarcus sp. BH72	4607149
YP_933465.1	CDS	oxoO1	NC_008702.1	2157971	2159311	R	Oxygenase component OxoO, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation.; Function unclear; putative 2-oxo-1 2-dihydroquinoline 8-monooxygenase oxygenase subunit	complement(2157971..2159311)	Azoarcus sp. BH72	4609463
YP_933466.1	CDS	azo1962	NC_008702.1	2159507	2160076	R	Conserved hypothetical flavin reductase. Homology to rsc0763 of R. solanacearum of 43% (TREMBL:Q8Y1C7). Pfam: Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. no signal peptide. no TMHs; Conserved hypothetical protein; flavin reductase	complement(2159507..2160076)	Azoarcus sp. BH72	4609461
YP_933467.1	CDS	azo1963	NC_008702.1	2160073	2161302	R	Conserved Hypothetical protein has strong similarity 70% and 51% identity to PUTATIVE OXYGENASE SUBUNIT PROTEIN [Ralstonia solanacearum GMI1000],TrEMBL:Q8XYC1, which has IPR003042; Rng_mnoxygenase and IPR001327; FAD_pyr_redox domain which is absent in this case. No Signal peptide or TMH being reported as present.; Function unclear; hypothetical protein	complement(2160073..2161302)	Azoarcus sp. BH72	4607150
YP_933468.1	CDS	azo1964	NC_008702.1	2161449	2162435	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(2161449..2162435)	Azoarcus sp. BH72	4607151
YP_933469.1	CDS	azo1965	NC_008702.1	2162520	2163521	R	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(2162520..2163521)	Azoarcus sp. BH72	4607152
YP_933470.1	CDS	todE	NC_008702.1	2163648	2164532	R	Methylcatechol 2,3-dioxygenase, TodE, is involved in the degradation of toluene. Similar to sprot|TODE_PSEPU (38%) and to trembl|Q52031 (36%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Specificity unclear; 3-methylcatechol 2,3-dioxygenase	complement(2163648..2164532)	Azoarcus sp. BH72	4607153
YP_933471.1	CDS	azo1967	NC_008702.1	2164557	2165000	R	Conserved hypothetical protein. Homology to Daro03003325 of Dechloromonas aromatica of 52% (gi|53729660|ref|ZP_00348498.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(2164557..2165000)	Azoarcus sp. BH72	4609956
YP_933472.1	CDS	xylF	NC_008702.1	2165047	2165901	R	TREMBL:Q93JW6: 67% identity, 81% similarity. 2-hydroxymuconic semialdehyde hydrolase (HMSH). hydrolysis of C-C bonds in ketonic substances CONVERSION OF 2-HYDROXYMUCONIC ACID SEMIALDEHYDE TO 2-HYDROXYPENT-24-DIENOATE. Pfam: abhydrolase: alpha/Beta hydrolase fold; thioesterase domain Absence of transmembrane helices (TMHMM predicted) prfB: peptide chain release factor 2; High confidence in function and specificity; 2-hydroxy-muconic semialdehyde hydrolase	complement(2165047..2165901)	Azoarcus sp. BH72	4607154
YP_933473.1	CDS	bphS	NC_008702.1	2166074	2166811	D	GntR family transcriptional regulator,; High confidence in function and specificity; GntR family transcriptional regulator	2166074..2166811	Azoarcus sp. BH72	4610134
YP_933474.1	CDS	azo1970	NC_008702.1	2166833	2167366	R	Conserved hypothetical protein. Homology to an orf of Rhizobium sp. NGR234 of 50% (tremblnew|AAQ87234(SRS)). No domain predicted. No signal peptide or TMH reported present.; hypothetical protein	complement(2166833..2167366)	Azoarcus sp. BH72	4608403
YP_933475.1	CDS	azo1971	NC_008702.1	2167420	2168526	R	SPROT:ADH1_BACST:31% identity; 45% similarity Alcohol dehydrogenase (EC 1.1.1.1) (ADH-T). THERMOSTABLE NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. an alcohol + nad(+) = an aldehyde or ketone + nadh. cofactor:binds 2 zinc ions per subunit (by similarity). InterPro: IPR002328; ADH_zinc. IPR002085:Adh_zn_family. Pfam:PF00107; ADH_zinc_N tdh: L-threonine 3-dehydrogenase; Specificity unclear; putative alcohol dehydrogenase	complement(2167420..2168526)	Azoarcus sp. BH72	4607155
YP_933476.1	CDS	mhpE	NC_008702.1	2168585	2169613	R	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase	complement(2168585..2169613)	Azoarcus sp. BH72	4607156
YP_933477.1	CDS	mhpF	NC_008702.1	2169628	2170548	R	catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase	complement(2169628..2170548)	Azoarcus sp. BH72	4609221
YP_933478.1	CDS	mhpD	NC_008702.1	2170617	2171411	R	This family consist of various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds, TREMBL:Q51981 (54% identity); SWISSPROT:P77608 (50% identity). InterPro (IPR002607): Hydratase/decarboxylase Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity; MhpD protein	complement(2170617..2171411)	Azoarcus sp. BH72	4609222
YP_933479.1	CDS	mhpB	NC_008702.1	2171448	2172401	R	catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase	complement(2171448..2172401)	Azoarcus sp. BH72	4609220
YP_933480.1	CDS	ohpC	NC_008702.1	2172426	2173322	R	Hypothetical protein Rv2715/MT2788/Mb2734. TREMBL:Q9KH20: 58% identity, 73% similarity 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; OhpC [Rhodococcus sp.] Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate. Pfam: alpha/ beta hydrolase; Ndr family; B12 binding domain. No signal peptide (Signal P predicted) or transmembrane helices (TMHMM predited) TIGRFAM: Co A. E activ TIGR00044: conserved hypothetical protein; Family membership; 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase	complement(2172426..2173322)	Azoarcus sp. BH72	4609218
YP_933481.1	CDS	oxoO2	NC_008702.1	2173724	2175064	R	Oxygenase component OxoO, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit arcC: carbamate kinase; Function unclear; putative 2-oxo-1 2-dihydroquinoline 8-monooxygenase oxygenase subunit	complement(2173724..2175064)	Azoarcus sp. BH72	4609439
YP_933482.1	CDS	azo1978	NC_008702.1	2175414	2176190	D	TREMBL:Q89PP9: 66% identity, 79% similarity. InterPro:IPR007325; Cyclase. Pfam:PF04199; Cyclase No signal peptide present. Absence of trans-membrane helices (TMHMM predicted).; Function unclear; hypothetical protein	2175414..2176190	Azoarcus sp. BH72	4609462
YP_933483.1	CDS	azo1979	NC_008702.1	2176634	2176756	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2176634..2176756	Azoarcus sp. BH72	4607157
YP_933484.1	CDS	azo1980	NC_008702.1	2176749	2178953	D	Conserved hypothetical indolepyruvate oxidoreductase, alpha subunit. Homology to mlr5448 of M. loti of 69% (trembl|Q98BS4). CATALYZES THE FERREDOXIN-DEPENDENT OXIDATIVE DECARBOXYLATION OF ARYLPYRUVATES (BY SIMILARITY). no signal peptide. no TMHs; Conserved hypothetical protein; indolepyruvate ferredoxin oxidoreductase subunit alpha	2176749..2178953	Azoarcus sp. BH72	4607158
YP_933485.1	CDS	azo1981	NC_008702.1	2178974	2180560	D	Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.; putative indolepyruvate oxidoreductase subunit B	2178974..2180560	Azoarcus sp. BH72	4607159
YP_933486.1	CDS	vanB2	NC_008702.1	2180606	2181583	D	Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 42% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership; vanillate O-demethylase oxidoreductase	2180606..2181583	Azoarcus sp. BH72	4607160
YP_933487.1	CDS	carBb2	NC_008702.1	2181600	2182922	D	Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB).; High confidence in function and specificity; putative dioxygenase hydroxylase large subunit	2181600..2182922	Azoarcus sp. BH72	4610091
YP_933488.1	CDS	carBa2	NC_008702.1	2183143	2183625	D	Hydroxylase large component of 1,2-dioxygenase complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyX: Benzoate 12-dioxygenase alpha subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). THE BETA SUBUNIT MAY BE RESPONSIBLE FOR THE SUBSTRATE SPECIFICITY OF THE ENZYME. InterPro: Aromatic-ring-hydroxylating dioxygenase beta subunit; High confidence in function and specificity; putative dioxygenase, hydroxylase small subunit	2183143..2183625	Azoarcus sp. BH72	4608419
YP_933489.1	CDS	azo1985	NC_008702.1	2183639	2185273	D	Similar to TREMBL:Q89PS8 (59% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme.; Function unclear; putative AMP-binding protein	2183639..2185273	Azoarcus sp. BH72	4608417
YP_933490.1	CDS	azo1986	NC_008702.1	2185270	2186448	D	Entry name TREMBL:Q89PQ1 Prim. accession # Q89PQ1 Identities = 241/381 (63%) Thiolase, N-terminal domain (Pfam predicted) Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; hypothetical protein	2185270..2186448	Azoarcus sp. BH72	4607161
YP_933491.1	CDS	azo1987	NC_008702.1	2186445	2187704	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear; short-chain dehydrogenase	2186445..2187704	Azoarcus sp. BH72	4607162
YP_933492.1	CDS	azo1988	NC_008702.1	2187853	2188638	D	TREMBL:Q8XYC3: 64% identity, 75% similarity Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site. InterPro:IPR007325; Cyclase. Pfam: PF04199; Cyclase Absence of signal peptide. Absence of transmembrane helices; Function unclear; hypothetical protein	2187853..2188638	Azoarcus sp. BH72	4607163
YP_933493.1	CDS	azo1989	NC_008702.1	2188649	2189377	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q7WG84 (46% identity); SWISSPROT:P17611 (30% identity). Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	2188649..2189377	Azoarcus sp. BH72	4607164
YP_933494.1	CDS	braC	NC_008702.1	2189440	2190591	D	The transport of branched-chain amino acids in P. aeruginosa is mediated by two distinct systems, the leucine, isoleucine, and valine I and II transports systems. Periplasmic binding proteins are found to participate in the transport of amino acids, sugars, and ions. BraC is the structural gene for periplasmic binding proteins in P. aeruginosa. Similar to trembl|Q9RYP6 (49%) and to sprot|BRAC_PSEAE (22%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative Leu/Ile/Val-binding protein	2189440..2190591	Azoarcus sp. BH72	4607165
YP_933495.1	CDS	azo1991	NC_008702.1	2190910	2191947	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q8XRX6 (55%) and to trembl|Q7WCY3 (53%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting nine Tmhelix.; Specificity unclear; ABC transporter permease	2190910..2191947	Azoarcus sp. BH72	4608404
YP_933496.1	CDS	azo1992	NC_008702.1	2191944	2193803	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. The integral inner-membrane proteins translocate the substrate across the membrane. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX5 (52%) and to trembl|Q89CG4 (45%). Pfam (PF00005): ABC transporter Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop) TMHMM reporting nine Tmhelix.; Specificity unclear; ABC transporter ATP-binding protein/permease	2191944..2193803	Azoarcus sp. BH72	4607166
YP_933497.1	CDS	azo1993	NC_008702.1	2193803	2194564	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (66%) and to trembl|Q89PQ7 (62%). Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	2193803..2194564	Azoarcus sp. BH72	4607167
YP_933498.1	CDS	apbA2	NC_008702.1	2195039	2196049	D	Putative 2-dehydropantoate 2-reductase (EC 1.1.1.169) (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Specificity unclear; 2-dehydropantoate 2-reductase	2195039..2196049	Azoarcus sp. BH72	4607168
YP_933499.1	CDS	azo1995	NC_008702.1	2196116	2196889	D	41% Aldolase_II_N. Class II Aldolase and Adducin N-terminal domain Pfam: PF00596; Aldolase_II; 1. fucA: L-fuculose phosphate aldolase; High confidence in function and specificity; hypothetical protein	2196116..2196889	Azoarcus sp. BH72	4608326
YP_933500.1	CDS	acS1	NC_008702.1	2197112	2198719	D	Acetyl-coenzyme A synthetase enables the cell to use acetate during aerobic growth to generate energy via the tca cycle, and biosynthetic compounds via the glyoxylate shunt. acetylates chey, the response regulator involved in flagellar movement and chemotaxis. Entry name SWISSPROT:ACSA_ECOLI Prim. accession # P27550 Identities = 145/546 (26%) Pfam PF00501; AMP-binding; 1. InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 1. Number of predicted TMHs: 0; Family membership; putative acetyl-coenzyme a synthetase	2197112..2198719	Azoarcus sp. BH72	4607169
YP_933501.1	CDS	badR	NC_008702.1	2198864	2199388	D	Putative transcriptional activatory protein BadR (Benzoate anaerobic degradation regulator). Similar to SWISSPROT: sprot|BADR_RHOPA (25% Rhodopseudomonas palustris, transcriptional activatory protein BadR (benzoate anaerobic degradation regulator)) InterPro: IPR000835 HTH_MarR. Pfam: PF01047 MarR family.; Family membership; MarR family transcriptional regulator	2198864..2199388	Azoarcus sp. BH72	4608272
YP_933502.1	CDS	azo1998	NC_008702.1	2199402	2200142	R	Catalyzes the phosphorolytic cleavage of 6-oxopurine nucleosides; 5'-methylthioadenosine phosphorylase	complement(2199402..2200142)	Azoarcus sp. BH72	4608374
YP_933503.1	CDS	typA	NC_008702.1	2200267	2202084	D	GTP-binding elongation factor,; High confidence in function and specificity; GTP-binding elongation factor	2200267..2202084	Azoarcus sp. BH72	4607170
YP_933504.1	CDS	galU	NC_008702.1	2202353	2203258	R	UTP--glucose-1-phosphate uridylyltransferase 1 (EC 2.7.7.9) (UDP- glucose pyrophosphorylase 1) (UDPGP 1) (Alpha-D-glucosyl-1-phosphate uridylyltransferase 1) (Uridine diphosphoglucose pyrophosphorylase 1). InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity; UTP-glucose-1-phosphate uridylyltransferase	complement(2202353..2203258)	Azoarcus sp. BH72	4610053
YP_933505.1	CDS	azo2001	NC_008702.1	2203255	2205336	R	DNA ligase (Polydeoxyribonucleotide synthase [NAD+]). This protein catalyzes the formation of phosphodiester linkages between 5-phosphoryl and 3-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. TIGRFAM: dnlj: DNA ligase NAD-dependent.; High confidence in function and specificity; DNA ligase	complement(2203255..2205336)	Azoarcus sp. BH72	4608857
YP_933506.1	CDS	azo2002	NC_008702.1	2205341	2206462	R	Conserved hypothetical membrane protein. Homology to ne2283 of N. europaea of 35% (trembl|Q82SM8(SRS)). Pfam: ZipA, C-ternial FtsZ-binding domaine. This family represents the ZipA C-terminal domain. ZipA is involved in septum formation in bacterial cell division. Its C-terminal domain binds FtsZ, a major component of the bacterial septal ring. The structure of this domain is an alpha-beta fold with three alpha helices and a beta sheet of six antiparallel beta strands. The major loops protruding from the beta sheet surface are thought to form a binding site for FtsZ. no singal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2205341..2206462)	Azoarcus sp. BH72	4607171
YP_933507.1	CDS	smc	NC_008702.1	2206478	2210014	R	Chromosome partition protein smc. PLAYS AN IMPORTANT ROLE IN CHROMOSOME STRUCTURE AND PARTITIONING. ESSENTIAL FOR CHROMOSOME PARTITION. InterPro: SMC family C-terminal domain; High confidence in function and specificity; chromosome segregation protein	complement(2206478..2210014)	Azoarcus sp. BH72	4607172
YP_933508.1	CDS	dapC	NC_008702.1	2210146	2211420	D	catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate; succinyldiaminopimelate transaminase	2210146..2211420	Azoarcus sp. BH72	4609876
YP_933509.1	CDS	dapD	NC_008702.1	2211431	2212252	D	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase	2211431..2212252	Azoarcus sp. BH72	4608582
YP_933510.1	CDS	azo2006	NC_008702.1	2212337	2213524	D	Tfp pilus retraction protein pilU, probable involved in twitching motility mechanism,; Specificity unclear; twitching motility protein	2212337..2213524	Azoarcus sp. BH72	4608583
YP_933511.1	CDS	dapE	NC_008702.1	2213566	2214708	D	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase	2213566..2214708	Azoarcus sp. BH72	4607173
YP_933512.1	CDS	azo2008	NC_008702.1	2214717	2215679	D	involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase	2214717..2215679	Azoarcus sp. BH72	4608584
YP_933513.1	CDS	rcp1	NC_008702.1	2215747	2216205	D	Putative Response regulator rcp1. Forms a two-component system with cph1 in which it acts as reciever substrate. Similar to SWISSPROT: sprot|RCP1_SYNY3 (30% Synechocystis sp., Rcp1) Pfam: PF00072 Response_reg.; Function unclear; putative two-component response regulator	2215747..2216205	Azoarcus sp. BH72	4607174
YP_933514.1	CDS	azo2010	NC_008702.1	2216245	2216439	R	Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384 ; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present.; hypothetical protein	complement(2216245..2216439)	Azoarcus sp. BH72	4609696
YP_933515.1	CDS	fdx2	NC_008702.1	2216436	2216780	R	Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI ). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity; Fdx2 protein	complement(2216436..2216780)	Azoarcus sp. BH72	4607175
YP_933516.1	CDS	hscA	NC_008702.1	2216777	2218645	R	involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA	complement(2216777..2218645)	Azoarcus sp. BH72	4608746
YP_933517.1	CDS	hscB	NC_008702.1	2218661	2219194	R	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB	complement(2218661..2219194)	Azoarcus sp. BH72	4607176
YP_933518.1	CDS	yfhF	NC_008702.1	2219199	2219522	R	Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation.; High confidence in function and specificity; putative regulatory protein	complement(2219199..2219522)	Azoarcus sp. BH72	4609030
YP_933519.1	CDS	iscU	NC_008702.1	2219543	2219926	R	NifU-related protein. Homology to iscU of A. vinelandii of 79% (trembl|O31270). IscU is a homologue of the N-terminal region of NifU, an protein MAY BE INVOLVED IN THE FORMATION OR REPAIR OF [FE-S] CLUSTERS PRESENT IN IRON-SULFUR PROTEINS mostly found in nitrogen-fixing bacteria. InterPro: NifU-like N terminal domain (IPR002871) Pfam: NifU-like N-terminal domain no signal peptide no TMHs; High confidence in function and specificity; scaffold protein	complement(2219543..2219926)	Azoarcus sp. BH72	4610173
YP_933520.1	CDS	iscS1	NC_008702.1	2219958	2221169	R	Cysteine desulfurase (NifS protein homolog). Homology to iscS of E. coli of 72% (sprot|ISCS_ECOLI). Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Functions as a sulfur delivery protein for nad, biotin and fe-s cluster synthesis. Pfam: Aminotransferase class V no signal peptide no TMHs; High confidence in function and specificity; cysteine desulfurase	complement(2219958..2221169)	Azoarcus sp. BH72	4609091
YP_933521.1	CDS	iscS2	NC_008702.1	2221203	2222351	R	Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership; cysteine desulfurase	complement(2221203..2222351)	Azoarcus sp. BH72	4609089
YP_933522.1	CDS	azo2018	NC_008702.1	2222358	2222840	R	RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic acid binding motif.; Family membership; Rrf2 family protein	complement(2222358..2222840)	Azoarcus sp. BH72	4609090
YP_933523.1	CDS	cysE	NC_008702.1	2222961	2223716	R	Probable serine acetyltransferase (EC 2.3.1.30). Homology to cysE of B. subtilis of 48% (sprot|CYSE_BACSU). no signal peptide no TMHs; Family membership; serine O-acetyltransferase	complement(2222961..2223716)	Azoarcus sp. BH72	4607177
YP_933524.1	CDS	azo2020	NC_008702.1	2223803	2224531	R	tRNA/rRNA methyltransferase; Specificity unclear; RNA methyltransferase	complement(2223803..2224531)	Azoarcus sp. BH72	4608557
YP_933525.1	CDS	suhB1	NC_008702.1	2224621	2225433	D	Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase) (Inositol-1- phosphatase) (I-1-Pase).May act by enhancing the synthesis or degradation of phosphorylated messenger molecules. Catalytic activity: myo-inositol 1-phosphate + h(2)o = myo- inositol + phosphate. 52% Inositol_P. Pfam:PF00459; inositol_P; 1.; High confidence in function and specificity; putative inositol-1-monophosphatase	2224621..2225433	Azoarcus sp. BH72	4607178
YP_933526.1	CDS	azo2022	NC_008702.1	2225579	2226112	R	Conserved hypotheticalsecreted protein. Homology to bll4707 of B.japonicum of 40% (tremble:Q89L41). No domains predicted. Signal P reporting signal peptide present. No TMH reported to be present.; Conserved hypothetical protein; hypothetical protein	complement(2225579..2226112)	Azoarcus sp. BH72	4609906
YP_933527.1	CDS	azo2023	NC_008702.1	2227005	2227280	D	Family membership; hypothetical protein	2227005..2227280	Azoarcus sp. BH72	4607179
YP_933528.1	CDS	yoeB	NC_008702.1	2227270	2227524	D	Conserved Hypothetical protein,[yoeB],69% identical(85% similarity) to SwissPort;P56605. TrEMBL;Q8FG53 Has PF05015, Plasmid maintenance system killer protein (IPR007711, Plasmid_killer) ;Several plasmids with proteic killer gene systems have been reported. All of them encode a stable toxin and an unstable antidote. Upon loss of the plasmid, the less stable inhibitor is inactivated more rapidly than the toxin, allowing the toxin to be activated. The activation of those systems result in cell filamentation and cessation of viable cell production. It has been verified that both the stable killer and the unstable inhibitor of the systems are short polypeptides. This family corresponds to the toxin. Has (IPR009614)PF06769, Protein of unknown function (DUF1224);This family consists of several short, hypothetical bacterial proteins of around 85 residues in length. The function of this family is unknown.; hypothetical protein	2227270..2227524	Azoarcus sp. BH72	4607180
YP_933529.1	CDS	azo2025	NC_008702.1	2227858	2228355	R	Conserved hypothetical acetyltransferase. Homology to glr3475 of G. violaceus of 40% (trembl|Q7NFP9). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Family membership; acetyltransferase	complement(2227858..2228355)	Azoarcus sp. BH72	4610195
YP_933530.1	CDS	azo2026	NC_008702.1	2228352	2228645	R	Conserved hypothetical protein. Homology to plu0180 of P.luminescens of 37% (trembl:Q7N9X1). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2228352..2228645)	Azoarcus sp. BH72	4607181
YP_933531.1	CDS	azo2027	NC_008702.1	2229090	2229269	D	Conserved hypothetical truncated transposase. Homology to Reut02001235 of Ralstonia metallidurans of 31% (gi|48772472|ref|ZP_00276814.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; Conserved hypothetical protein; putative transposase	2229090..2229269	Azoarcus sp. BH72	4607182
YP_933532.1	CDS	azo2028	NC_008702.1	2229309	2229731	D	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	2229309..2229731	Azoarcus sp. BH72	4607183
YP_933533.1	CDS	azo2029	NC_008702.1	2229758	2230090	D	Conserved hypothetical transposase. Homology to ebB8 of Azoarcus sp. EbN1 of 91% (gnl|keqq|eba:ebB8(KEGG)). Pfam: IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition. No signal peptide. Probable 1 TMHs; Conserved hypothetical protein; putative transposase	2229758..2230090	Azoarcus sp. BH72	4607184
YP_933534.1	CDS	azo2030	NC_008702.1	2230168	2230368	D	Hypothetical truncated transposase. Homology to the N-terminus of ebA290 of Azoarcus sp. EbN1 of 92% (gnl|keqq|eba:ebA290(KEGG)). No domains predicted. No signal peptide. No TMHs.; putative transposase	2230168..2230368	Azoarcus sp. BH72	4607185
YP_933535.1	CDS	azo2031	NC_008702.1	2230396	2231724	D	Hypothetical truncated transposase. Homology to the C-terminus of ebA290 of Azoarcus sp. EbN1 of 67% (gnl|keqq|eba:ebA290(KEGG)). Pfam: Transposase IS66 family. No signal peptide. No TMHs; putative transposase	2230396..2231724	Azoarcus sp. BH72	4607186
YP_933536.1	CDS	azo2032	NC_008702.1	2231721	2232221	D	Hypothetical protein, very weak homology with hits in the database. Has No domains, repeats, motifs or features detected.; hypothetical protein	2231721..2232221	Azoarcus sp. BH72	4607187
YP_933537.1	CDS	azo2033	NC_008702.1	2232140	2232754	R	Hypothetical truncated transposase. Homology to the N-terminus of tnp16A of Azoarcus sp. EbN1 of 54% (gnl|keqq|eba:ebA690(KEGG)). No domains predicted. No TMHs. No signal peptide.; putative transposase	complement(2232140..2232754)	Azoarcus sp. BH72	4607188
YP_933538.1	CDS	azo2034	NC_008702.1	2232808	2233167	R	Conserved hypothetical transposase helper protein. Homology to ebB98 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebB98(KEGG)). Pfam: IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition. No signal peptide. No TMHs.; Conserved hypothetical protein; putative transposase helper protein	complement(2232808..2233167)	Azoarcus sp. BH72	4607189
YP_933539.1	CDS	azo2035	NC_008702.1	2233167	2233475	R	Conserved hypothetical protein. Homology to ebD29 of Azoarcus sp. EbN1 of 55% (gnl|keqq|eba:ebD29(KEGG)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(2233167..2233475)	Azoarcus sp. BH72	4607190
YP_933540.1	CDS	azo2036	NC_008702.1	2234650	2235642	R	hypothetical protein	complement(2234650..2235642)	Azoarcus sp. BH72	4607191
YP_933541.1	CDS	azo2037	NC_008702.1	2236135	2236755	R	Conserved hypothetical protein. Homology to XAC2237 of X.axonopodis of 33% (trembl:Q8PKD8). No domain predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2236135..2236755)	Azoarcus sp. BH72	4607192
YP_933542.1	CDS	azo2038	NC_008702.1	2237096	2237575	R	Conserved hypothetical protein. Homology to RL074 of Pseudomonas aeruginosa of 34% (trembl:Q7WXY6). No domains predicted. No TMHs. No singal peptide.; hypothetical protein	complement(2237096..2237575)	Azoarcus sp. BH72	4607193
YP_933543.1	CDS	azo2039	NC_008702.1	2237967	2238542	D	Hypothetical protein predicted by Glimmer/Gritica. No homology to the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	2237967..2238542	Azoarcus sp. BH72	4607194
YP_933544.1	CDS	repA	NC_008702.1	2238649	2239074	D	Probable replicase,functional similarity(67%) to TrEMBL Q6I6A6,PF04796;IPR006881 Has pfam04796, RepA_C domain, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood. No Signal peptide or TMH are reported to be present.; Specificity unclear; replicase RepA	2238649..2239074	Azoarcus sp. BH72	4607195
YP_933545.1	CDS	azo2041	NC_008702.1	2239144	2239623	D	Probable replicase(repA),functional similarity(67%) to TrEMBL Q6I6A6,PF04796;IPR006881 Has pfam04796, RepA_C domain, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood. No Signal peptide or TMH are reported to be present.; protein kinase	2239144..2239623	Azoarcus sp. BH72	4609714
YP_933546.1	CDS	azo2042	NC_008702.1	2239863	2240681	D	Conserved hypothetical membrane protein. Homology to ebA436 of Azoarcus sp. EbN1 of 49% (gnl|keqq|eba:ebA436(KEGG)). No domains predicted. No signal peptide. TMHMM2 reporting presence of 2 TMH's.; Conserved hypothetical protein; hypothetical protein	2239863..2240681	Azoarcus sp. BH72	4607196
YP_933547.1	CDS	azo2043	NC_008702.1	2240702	2241337	D	Conserved hypothetical secreted protein. Homology to ebA439 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA439(KEGG)). No domains predicted. No TMHs signal peptide present.; Conserved hypothetical protein; hypothetical protein	2240702..2241337	Azoarcus sp. BH72	4607197
YP_933548.1	CDS	azo2044	NC_008702.1	2241354	2241563	D	Conserved hypothetical protein. No homology to a protein of similar size in the data base. No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2241354..2241563	Azoarcus sp. BH72	4607198
YP_933549.1	CDS	azo2045	NC_008702.1	2242277	2244052	D	Hypothetical protein, 28% identity (45% similarity) to TrEMBL;Q7VHD7. Weak homology with hits in the Database spanning the entire lenghth of Protein. Has PF03235,Protein of unknown function DUF262; Interpro;IPR004919.; Function unclear; hypothetical protein	2242277..2244052	Azoarcus sp. BH72	4607199
YP_933550.1	CDS	azo2046	NC_008702.1	2244049	2246235	D	Hypothetical protein 27% identity to TrEMBL;Q7VHD8. Signal Peptide, or any known features not present.; hypothetical protein	2244049..2246235	Azoarcus sp. BH72	4607200
YP_933551.1	CDS	radC2	NC_008702.1	2246568	2247158	D	DNA repair protein radC homolog.; High confidence in function and specificity; DNA repair protein	2246568..2247158	Azoarcus sp. BH72	4607201
YP_933552.1	CDS	azo2048	NC_008702.1	2247594	2248190	D	Hypothetical protein yfdR. The HD domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved in the nucleic acid metabolism, signal transduction and possibly other functions in bacteria,archaea and eukaryotes TREMBL:Q8HAA3: 41% identity,52% similarity InterPro:IPR003607; Met_phsphohydro. SMART:SM00471; HDc hstdl_phs_rel: histidinol phosphatase-r No signal peptide No transmembrane helices; Function unclear; hypothetical protein	2247594..2248190	Azoarcus sp. BH72	4609692
YP_933553.1	CDS	azo2049	NC_008702.1	2248683	2248952	D	Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs; hypothetical protein	2248683..2248952	Azoarcus sp. BH72	4607202
YP_933554.1	CDS	azo2050	NC_008702.1	2249016	2250140	R	Putative H repeat-associated protein PF01609 Transposase_11, Transposase DDE domain. Transposases are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda. SignalP reporting signal Peptide to be present No TMH reproted as present.; High confidence in function and specificity; H repeat-containing protein	complement(2249016..2250140)	Azoarcus sp. BH72	4607203
YP_933555.1	CDS	azo2051	NC_008702.1	2250271	2251566	R	Integrase. INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION WITH EXCISIONASE INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE PROPHAGE FROM THE HOST GENOME. InterPro: Phage integrase; High confidence in function and specificity; phage integrase family site specific recombinase	complement(2250271..2251566)	Azoarcus sp. BH72	4607204
YP_933556.1	CDS	azo2052	NC_008702.1	2251818	2254355	D	This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS	2251818..2254355	Azoarcus sp. BH72	4607205
YP_933557.1	CDS	speE1	NC_008702.1	2254352	2255107	D	Spermidine synthase (Putrescine aminopropyltransferase),; Conserved hypothetical protein; putative spermidine synthase	2254352..2255107	Azoarcus sp. BH72	4607206
YP_933558.1	CDS	dnaQ	NC_008702.1	2255112	2255831	R	DNA polymerase III epsilon chain. DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THE EPSILON SUBUNIT CONTAIN THE EDITING FUNCTION AND IS A PROOFREADING 3-5 EXONUCLEASE (BY SIMILARITY). InterPro: Exonuclease. TIGRFAM: dnaq: DNA polymerase III epsilon chain.; High confidence in function and specificity; DNA-directed DNA polymerase	complement(2255112..2255831)	Azoarcus sp. BH72	4609887
YP_933559.1	CDS	rnhA2	NC_008702.1	2255849	2256307	R	Ribonuclease H (RNase H). This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically (By similarity).; High confidence in function and specificity; ribonuclease H	complement(2255849..2256307)	Azoarcus sp. BH72	4608639
YP_933560.1	CDS	azo2056	NC_008702.1	2256308	2257072	R	Similar to TREMBL:Q82XV9 (41% identity, generic methyl-transferase); TREMBL:Q7NYL9 (45% identity).; hypothetical protein	complement(2256308..2257072)	Azoarcus sp. BH72	4609753
YP_933561.1	CDS	gloB2	NC_008702.1	2257071	2257832	D	Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase II) (Glx II). Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid.Similarity to bacterial stress protein TerD. 49% identity and 64% similarity to similar product from Nitrosomonas europaea ATCC InterPro: Metallo-beta-lactamase superfamily CoA_E_activ: CoA-substrate-specific enz; Family membership; hydroxyacylglutathione hydrolase	2257071..2257832	Azoarcus sp. BH72	4607207
YP_933562.1	CDS	ccdB	NC_008702.1	2257836	2258222	R	Probable response regulator,; Specificity unclear; response regulator	complement(2257836..2258222)	Azoarcus sp. BH72	4608910
YP_933563.1	CDS	wspR1	NC_008702.1	2258225	2259202	R	Probable REC/GGDEF-domain containing protein,; Function unclear; REC/GGDEF-domain-containing protein	complement(2258225..2259202)	Azoarcus sp. BH72	4608443
YP_933564.1	CDS	azo2060	NC_008702.1	2259430	2260878	D	Region start changed from 2259236 to 2259431 (-195 bases); membrane-bound lytic murein transglycosylase D	2259430..2260878	Azoarcus sp. BH72	4610115
YP_933565.1	CDS	dppF	NC_008702.1	2260891	2262891	R	Hypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity; ABC transporter ATP-binding protein	complement(2260891..2262891)	Azoarcus sp. BH72	4607208
YP_933566.1	CDS	azo2062	NC_008702.1	2262996	2263481	R	Conserved hypothetical peptidyl-prolyl cis-trans isomerase. Homology to slyD of E. coli of 41% (sprot|SLYD_ECOLI) but around 30 aa at the C-terminus are missing. Peptidylprolyl isomerases accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) (IPR001179). Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase. no signal peptide. no TMHs; Family membership; peptidyl-prolyl cis-trans isomerase	complement(2262996..2263481)	Azoarcus sp. BH72	4608647
YP_933567.1	CDS	bcp1	NC_008702.1	2263441	2263950	R	Putative bacterioferritin comigratory protein. Homology to bcp of E. coli of 37% (srot:BCP_ECOLI) Interpro: Alkyl hydroperoxid reductase/ Thiol specific antioxidant / Mal Alergern (IPR000866) Pfam: AhpcC/TSA family no signal peptide no TMH; Family membership; putative bacterioferritin comigratory protein	complement(2263441..2263950)	Azoarcus sp. BH72	4607209
YP_933568.1	CDS	lexA	NC_008702.1	2264217	2264825	D	Represses a number of genes involved in the response to DNA damage; LexA repressor	2264217..2264825	Azoarcus sp. BH72	4608379
YP_933569.1	CDS	azo2065	NC_008702.1	2264839	2265489	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 4 TMHs; hypothetical protein	2264839..2265489	Azoarcus sp. BH72	4609134
YP_933570.1	CDS	norM	NC_008702.1	2265492	2266883	D	The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae,and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. Functions as a Na(+)/drug antiporter. These proteins have 12 probable TMS,TREMBL:Q7NXN3 (35% identity); SWISSPROT:Q9K015 (32% identity). Pfam (UPF0013): Uncharacterized membrane protein family. TIGRFAM (TIGR00797): matE. TMHMM reporting 11 transmembrane helices. TC (2.A.66.1.): The Multi Antimicrobial Extrusion (MATE) Family.; High confidence in function and specificity; multidrug resistance protein	2265492..2266883	Azoarcus sp. BH72	4607210
YP_933571.1	CDS	azo2067	NC_008702.1	2266889	2267239	R	Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier). REDUCTION OF ARSENATE [AS(V)] TO ARSENITE [AS(III)]. THIS PROTEIN EXPANDS THE SUBSTRATE SPECIFICITY OF ARSAB PUMP WHICH CAN EXTRUDE ARSENITE AND ANTIMONITE TO ALLOW FOR ARSENATE PUMPING AND RESISTANCE. arsC: arsenate reductase; High confidence in function and specificity; arsenate reductase	complement(2266889..2267239)	Azoarcus sp. BH72	4609398
YP_933572.1	CDS	azo2068	NC_008702.1	2267239	2269050	R	Conserved hypothetical protein. Homology to rsc2890 of R. solanacearum of 53% (trembl|Q8XVE1). InterPro: PDZ domain (also known as DHR or GLGF)(IPR001478). Pfam: PDZ domain (also known as DHR or GLGF); M61 glycyl aminopeptidase PDZ domains are found in diverse signaling proteins in bacteria, yeasts, plants, insects and vertebrates. They may function in targeting signalling molecules to sub-membranous sites. Some PDZs have been shown to bind C-terminal polypeptides; others appear to bind internal (non-C-terminal) polypeptides. Different PDZs possess different binding specificities. Glycyl aminopeptidase is an unusual peptidase in that it has a preference for substrates with an N-terminal glycine or alanine. no signal peptide. no TMHs.; Family membership; hypothetical protein	complement(2267239..2269050)	Azoarcus sp. BH72	4607211
YP_933573.1	CDS	azo2069	NC_008702.1	2269613	2271997	R	Region start changed from 2272064 to 2271998 (-66 bases); ATP-dependent protease La	complement(2269613..2271997)	Azoarcus sp. BH72	4610028
YP_933574.1	CDS	clpX	NC_008702.1	2272107	2273375	R	binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX	complement(2272107..2273375)	Azoarcus sp. BH72	4607213
YP_933575.1	CDS	clpP	NC_008702.1	2273393	2274031	R	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit	complement(2273393..2274031)	Azoarcus sp. BH72	4608491
YP_933576.1	CDS	tig	NC_008702.1	2274050	2275363	R	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor	complement(2274050..2275363)	Azoarcus sp. BH72	4608489
YP_933577.1	CDS	prkA	NC_008702.1	2275699	2277621	D	Putative serine protein kinase. Homology to prkA of Bacillus subtilis of 32% (gnl|keqq|bsu:BG10804 ). Pfam: PrkA serine kinase. This is a family of PrkA bacterial and archaeal serine kinases approximately 630 residues long. PrkA possesses the A-motif of nucleotide-binding proteins and exhibits distant homology to eukaryotic protein kinases. Note that many family members are hypothetical. Interpro: IPR010650 PrkA serine kinase. No signal peptide. No TMHs.,; Family membership; PrkA protein	2275699..2277621	Azoarcus sp. BH72	4609947
YP_933578.1	CDS	yeaH	NC_008702.1	2277682	2278950	D	Conserved hypothetical protein,[yeaH]54% identical (71% similarity )to SwissProt;P59349. Has PF04285(IPR006698), Protein of unknown function (DUF444);Bacterial protein of unknown function. One family member (Q97LI1) is predicted to contain a von Willebrand factor (vWF) type A domain (Smart:VWA). No Signal peptide or TMH present.; hypothetical protein	2277682..2278950	Azoarcus sp. BH72	4609628
YP_933579.1	CDS	ycgB	NC_008702.1	2278947	2280482	D	Putative cytoplasmic protein[ycgB],67% identical (79% similarity) SwissProt;P29013. TrEMBL;Q8XDL3(67% identical)TrEMBL;Q8ZP16. Has PF04293, SpoVR like protein;IPR007390; Family member P37875 is Bacillus subtilis stage V sporulation protein R,which is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR. No Signal peptide or TMH present.; Family membership; SpoVR family protein	2278947..2280482	Azoarcus sp. BH72	4610165
YP_933580.1	CDS	azo2076	NC_008702.1	2280524	2282053	D	38% UPF0031.IPR004443; YjeF_Nterm. Pfam:PF01256; Carb_kinase; 1.PF03853; YjeF_N; 1. TIGRFAMs:TIGR00196; yjeF_cterm; 1.TIGR00197; yjeF_nterm; 1.; Specificity unclear; hypothetical protein	2280524..2282053	Azoarcus sp. BH72	4610158
YP_933581.1	CDS	azo2077	NC_008702.1	2282131	2283384	D	HD-domain containing protein,; Conserved hypothetical protein; HD-domain-containing protein	2282131..2283384	Azoarcus sp. BH72	4607214
YP_933582.1	CDS	azo2078	NC_008702.1	2283461	2284315	D	Conserved hypothetical membrane protein. Homology to PA0239 pf P. aeruginosa of 41%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport. Pfam: Integral membrane protein DUF6. 10 TMHs. no signal peptide; Conserved hypothetical protein; hypothetical protein	2283461..2284315	Azoarcus sp. BH72	4607215
YP_933583.1	CDS	nadC	NC_008702.1	2284399	2285247	D	Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase). TIGRFAM: nadC: nicotinate-nucleotide pyrophosphorylase; High confidence in function and specificity; nicotinate-nucleotide diphosphorylase	2284399..2285247	Azoarcus sp. BH72	4607216
YP_933584.1	CDS	thrC	NC_008702.1	2285402	2286865	R	catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase	complement(2285402..2286865)	Azoarcus sp. BH72	4609304
YP_933585.1	CDS	hom	NC_008702.1	2287025	2288332	R	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase	complement(2287025..2288332)	Azoarcus sp. BH72	4609944
YP_933586.1	CDS	yfbQ	NC_008702.1	2288377	2289705	R	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT	complement(2288377..2289705)	Azoarcus sp. BH72	4609015
YP_933587.1	CDS	azo2083	NC_008702.1	2289870	2290250	D	Conserved hypothetical protein. Homology to RS02847 of R.solanacearum of 49% (trembl:Q8XZS0). Has PF04635,Protein of unknown function, DUF598;IPR006729; This family contains several uncharacterised proteins. No signal peptide or TMH present.; hypothetical protein	2289870..2290250	Azoarcus sp. BH72	4610170
YP_933588.1	CDS	azo2084	NC_008702.1	2290256	2291482	R	Member of the Major Facilitator Superfamily (MFS). MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Hypothetical transport protein yjjL. InterPro: General substrate transporters 2A0104: phosphoglycerate transporter; Function unclear; putative membrane transport protein	complement(2290256..2291482)	Azoarcus sp. BH72	4607217
YP_933589.1	CDS	xanB	NC_008702.1	2291561	2293009	R	Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership; xanthan biosynthesis protein XanB	complement(2291561..2293009)	Azoarcus sp. BH72	4607218
YP_933590.1	CDS	azo2086	NC_008702.1	2293152	2293907	R	Putative transcriptional activator protein,; Function unclear; putative transcriptional activator protein	complement(2293152..2293907)	Azoarcus sp. BH72	4610122
YP_933591.1	CDS	xcmX	NC_008702.1	2293904	2294440	R	In Pseudomonas putida strain GB-1, XcmX is involved in a novel Xcp-related system for the transport of manganese-oxidizing enzymes to the cell surface. Similar trembl|Q8KSG3 (33%). TMHMM reporting one TMH. SignalP reporting a signal peptid.; Function unclear; putative Gsp-related pathway protein	complement(2293904..2294440)	Azoarcus sp. BH72	4607219
YP_933592.1	CDS	azo2088	NC_008702.1	2294427	2294819	R	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide.; Conserved hypothetical protein; hypothetical protein	complement(2294427..2294819)	Azoarcus sp. BH72	4610123
YP_933593.1	CDS	gspG1	NC_008702.1	2294825	2295301	R	General secretion pathway protein G,; Specificity unclear; general secretion pathway protein G	complement(2294825..2295301)	Azoarcus sp. BH72	4607220
YP_933594.1	CDS	gspD2	NC_008702.1	2295298	2297325	R	Protein D is involved in the type II general secretion pathway within Gram-negative bacteria, a signal sequence-dependent process responsible for protein export. The most probable location of protein D is the outer membrane. This suggests that protein D constitutes the apparatus of the accessory mechanism, and is thus involved in transporting exoproteins from the periplasm, across the outer membrane, to the extracellular environment. Similar to trembl|Q8XTG8 (39%). Pfam (PF00263): General (type II) secretion pathway (GSP) D protein Pfam (PF07660): Secretin and TonB N terminus short domain Pfam (PF03958): Bacterial type II/III secretion system short domain SignalP reporting Signal peptide.; Specificity unclear; general secretion pathway protein D	complement(2295298..2297325)	Azoarcus sp. BH72	4608954
YP_933595.1	CDS	azo2091	NC_008702.1	2297322	2297813	R	Conserved hypothetical secreted protein. Homology to rs02976 of R. solanacearum of 35% (trembl|Q8XTG7(SRS)). No domains predicted. Signal peptide present. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(2297322..2297813)	Azoarcus sp. BH72	4608948
YP_933596.1	CDS	azo2092	NC_008702.1	2297810	2298373	R	Conserved hypothetical membrane protein. Homology to ebA1234 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA1234(KEGG)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2297810..2298373)	Azoarcus sp. BH72	4607221
YP_933597.1	CDS	azo2093	NC_008702.1	2298370	2298918	R	Conserved hypothetical protein. Homology to ebA1229 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA1229(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2298370..2298918)	Azoarcus sp. BH72	4607222
YP_933598.1	CDS	azo2094	NC_008702.1	2298915	2299715	R	Conserved hypothetical protein. Homology to ebD34 of Azoarcus sp. EbN1 of 33% (gnl|keqq|eba:ebD34(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2298915..2299715)	Azoarcus sp. BH72	4607223
YP_933599.1	CDS	gspE2	NC_008702.1	2299696	2301372	R	General secretion pathway protein E (Type II traffic warden ATPase) INVOLVED IN A GENERAL SECRETION PATHWAY (GSP) FOR THE EXPORT OF PROTEINS. Similar to sprot|PILF_NEIGO (33%) and trembl|Q82U87 (54%). InterPro (PF00437): Bacterial type II secretion system protein E InterPro (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; general secretion pathway protein E	complement(2299696..2301372)	Azoarcus sp. BH72	4607224
YP_933600.1	CDS	gspF2	NC_008702.1	2301369	2302541	R	General secretion pathway protein F,similar trembl|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial general secretion pathway protein F TMHMM reporting five TMH.; Specificity unclear; general secretion pathway protein F	complement(2301369..2302541)	Azoarcus sp. BH72	4608950
YP_933601.1	CDS	gspG2	NC_008702.1	2302565	2303020	R	General secretion pathway GSPG-related transmembrane protein,; Specificity unclear; general secretion pathway protein G	complement(2302565..2303020)	Azoarcus sp. BH72	4608953
YP_933602.1	CDS	slt	NC_008702.1	2303193	2303888	D	Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) (Slt70). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). flhB_rel: FlhB domain protein; Family membership; soluble lytic murein transglycosylase	2303193..2303888	Azoarcus sp. BH72	4608955
YP_933603.1	CDS	azo2099	NC_008702.1	2303995	2305512	D	Conserved hypothetical secreted protein. Homology to xac2776 of X. axonopodis of 50% (trembl|Q8PIW9). Pfam: DUF839 This family consists of several bacterial proteins of unknown function. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2303995..2305512	Azoarcus sp. BH72	4609873
YP_933604.1	CDS	azo2100	NC_008702.1	2305593	2306900	R	catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase	complement(2305593..2306900)	Azoarcus sp. BH72	4607225
YP_933605.1	CDS	azo2101	NC_008702.1	2307012	2307671	R	Hypothetical membrane protein. No homology with hits in the database. No domains predicted. Signal peptide present. TMHMM2 reporting 1 TMH present.; hypothetical protein	complement(2307012..2307671)	Azoarcus sp. BH72	4607226
YP_933606.1	CDS	dksA2	NC_008702.1	2308537	2308899	D	DnaK suppressor protein,; High confidence in function and specificity; DksA2 protein	2308537..2308899	Azoarcus sp. BH72	4610015
YP_933607.1	CDS	pnp	NC_008702.1	2308958	2311057	R	Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase). Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3 to 5 direction. Involved in the RNA degradosome a multi-enzyme complex important in RNA processing and messenger RNA degradation.; High confidence in function and specificity; polynucleotide phosphorylase/polyadenylase	complement(2308958..2311057)	Azoarcus sp. BH72	4608625
YP_933608.1	CDS	rpsO	NC_008702.1	2311255	2311524	R	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15	complement(2311255..2311524)	Azoarcus sp. BH72	4609589
YP_933609.1	CDS	truB	NC_008702.1	2311618	2312520	R	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B	complement(2311618..2312520)	Azoarcus sp. BH72	4609818
YP_933610.1	CDS	rbfA	NC_008702.1	2312537	2312917	R	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A	complement(2312537..2312917)	Azoarcus sp. BH72	4610038
YP_933611.1	CDS	infB	NC_008702.1	2312921	2315743	R	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2	complement(2312921..2315743)	Azoarcus sp. BH72	4607228
YP_933612.1	CDS	nusA	NC_008702.1	2315757	2317232	R	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA	complement(2315757..2317232)	Azoarcus sp. BH72	4609083
YP_933613.1	CDS	azo2109	NC_008702.1	2317260	2317694	R	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein	complement(2317260..2317694)	Azoarcus sp. BH72	4609433
YP_933614.1	CDS	azo2110	NC_008702.1	2317918	2318988	R	Conserved hypothetical protein; Family membership; pseudouridylate synthase	complement(2317918..2318988)	Azoarcus sp. BH72	4607229
YP_933615.1	CDS	scpB	NC_008702.1	2318924	2319532	R	Putative segregation and condensation protein B,; Conserved hypothetical protein; putative segregation and condensation protein B	complement(2318924..2319532)	Azoarcus sp. BH72	4607230
YP_933616.1	CDS	azo2112	NC_008702.1	2319510	2320340	R	Hypothetical protein, 51% identity(64% similarity) to TrEMBL;Q8XWT4. Has PF02616, Uncharacterised ACR,COG1354;This entry describes proteins of unknown function. InterPro; IPR003768; Specificity unclear; hypothetical protein	complement(2319510..2320340)	Azoarcus sp. BH72	4609852
YP_933617.1	CDS	azo2113	NC_008702.1	2320366	2321025	R	Conserved hypothetical membrane protein. Homology to NE1726 of N.europaea of 61% (trembl:Q82TY8). InterPro: IPR008915; Peptidase_M50. Pfam: PF02163; Peptidase_M50. Non-secretory protein signal peptide probability: 0.235. TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein; hypothetical protein	complement(2320366..2321025)	Azoarcus sp. BH72	4607231
YP_933618.1	CDS	azo2114	NC_008702.1	2321072	2321704	R	InterPro: Sua5/YciO/YrdC/YwlC protein family TIGR00057: Sua5/YciO/YrdC/YwlC family p; High confidence in function and specificity; hypothetical protein	complement(2321072..2321704)	Azoarcus sp. BH72	4607232
YP_933619.1	CDS	trpH	NC_008702.1	2321712	2322563	R	TREMBL:Q7VZ25: 48% identity; 57% similarity SWISSPROT:TRPH_HAEIN:Protein trpH (38% identity). InterPro:IPR003141; PHP_N.PHP domain C-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. This family is often associated with an N-terminal region Pfam: PF02231; PHP_N; SMART: SM00481; POLIIIAc; thiE: thiamine-phosphate pyrophosphoryl; High confidence in function and specificity; hypothetical protein	complement(2321712..2322563)	Azoarcus sp. BH72	4607233
YP_933620.1	CDS	azo2116	NC_008702.1	2322571	2323473	R	Probable Serine hydrolase-like protein (EC 3.1.-.-). TREMBL:Q8Y0A9: 49% identity, 63% similarity. Pfam: abhydrolase; thioesterase TIGRFAM: murB: UDP-N-acetylenolpyruvoylglucosamine No transmembrane helix (predicted by TMHMM); Function unclear; hydrolase or acytransferase	complement(2322571..2323473)	Azoarcus sp. BH72	4610036
YP_933621.1	CDS	azo2117	NC_008702.1	2323493	2323834	D	Hypothetical protein. Very bad homology with hits. Has No domains, repeats, motifs or features detected.; hypothetical protein	2323493..2323834	Azoarcus sp. BH72	4607234
YP_933622.1	CDS	azo2118	NC_008702.1	2323896	2324195	D	Conserved hypothetical protein. Very Bad homology with hits in the database. Has SMART;SM00438;IPR000967,Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C, where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C.; hypothetical protein	2323896..2324195	Azoarcus sp. BH72	4607235
YP_933623.1	CDS	pcD	NC_008702.1	2324230	2325735	D	probable piperideine-6-carboxylate dehydrogenase. Homology to pcd of F. lutescens of 53% (trembl|Q9F1U8) InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership; piperideine-6-carboxylate dehydrogenase	2324230..2325735	Azoarcus sp. BH72	4607236
YP_933624.1	CDS	ylqF	NC_008702.1	2325732	2326607	R	Hypothetical protein MG442 homolog (K05_orf271). TREMBL:Q7NR72: 48% identity, 66% similarity InterPro; IPR005289; GTP-bindding_dom. InterPro; IPR002917; MMR_HSR1. Pfam; PF01926; MMR_HSR1; thiE: thiamine-phosphate pyrophosphor NO signal peptide No transmembrane helices; Specificity unclear; GTPase	complement(2325732..2326607)	Azoarcus sp. BH72	4609508
YP_933625.1	CDS	cspA	NC_008702.1	2326914	2327123	D	Cold shock-like protein,; High confidence in function and specificity; cold shock-like protein	2326914..2327123	Azoarcus sp. BH72	4610193
YP_933626.1	CDS	deaD	NC_008702.1	2327305	2329257	D	Cold-shock DEAD-box protein A (ATP-dependent RNA helicase deaD). HAS A HELIX-DESTABILIZING ACTIVITY. PLAYS A KEY ROLE IN OPTIMAL CELL GROWTH AT LOW TEMPERATURE AND IS REQUIRED FOR NORMAL CELL DIVISION (BY SIMILARITY).; Family membership; ATP-dependent RNA helicase	2327305..2329257	Azoarcus sp. BH72	4608538
YP_933627.1	CDS	tesA2	NC_008702.1	2329257	2329883	D	Putative acyl-CoA thioesterase. Homology to tesA of E. coli of 32% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase GDSL-like motif signal peptide no TMH; Family membership; putative acyl-CoA thioesterase I	2329257..2329883	Azoarcus sp. BH72	4608614
YP_933628.1	CDS	azo2124	NC_008702.1	2329949	2330935	D	catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase	2329949..2330935	Azoarcus sp. BH72	4609929
YP_933629.1	CDS	azo2125	NC_008702.1	2331002	2331898	D	TREMBL:Q9HT60:67% identity, 80% similarity to putative hydrolase. Hypothetical protein yqjL. InterPro: Alpha/beta hydrolase fold Pfam: abhydrolase; thioesterase domain uppS: undecaprenyl diphosphate synthase; Specificity unclear; hypothetical protein	2331002..2331898	Azoarcus sp. BH72	4607237
YP_933630.1	CDS	yaeQ	NC_008702.1	2331887	2332435	R	Putative cytoplasmic protein [yaeQ],49% identity (64% similarity) to TrEMBL;Q79ID7. TrEMBL;Q8FKZ7(57% identity) SwissProt;P52100. Has PF07152, YaeQ protein;This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialised transcription elongation protein. YaeQ is known to compensate for loss of RfaH function. No Signal Peptide or TMH present.; High confidence in function and specificity; putative cytoplasmic protein	complement(2331887..2332435)	Azoarcus sp. BH72	4607238
YP_933631.1	CDS	azo2127	NC_008702.1	2332443	2333228	R	Conserved hypothetical protein. Homology to ebA6182 Azoarcus sp. EbN1 of 55% (gnl|keqq|eba:ebA6182(KEGG)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(2332443..2333228)	Azoarcus sp. BH72	4610137
YP_933632.1	CDS	azo2128	NC_008702.1	2333487	2334902	D	GGDEF-domain containing protein,; Conserved hypothetical protein; diguanylate cyclase	2333487..2334902	Azoarcus sp. BH72	4607239
YP_933633.1	CDS	azo2129	NC_008702.1	2334907	2335401	R	Hypothetical protein, 32% identity to TrEMBL;Q6MXJ8. No Signal Peptide, features or Domains present.; hypothetical protein	complement(2334907..2335401)	Azoarcus sp. BH72	4607240
YP_933634.1	CDS	fabI2	NC_008702.1	2335612	2336391	D	Catalytic activity :-acyl-[acyl-carrier protein] + nad(+) = trans- 2,3-dehydroacyl-[acyl-carrier protein] + nadh. pathway:- fatty acid biosynthesis pathway; second reduction step. Entry name SWISSPROT:FABI_ECOLI InterPro IPR002198; ADH_short. Identities = 108/252 (42%) Pfam PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; High confidence in function and specificity; enoyl-(acyl carrier protein) reductase	2335612..2336391	Azoarcus sp. BH72	4607241
YP_933635.1	CDS	azo2131	NC_008702.1	2336402	2336998	D	Conserved hypothetical protein. Homology to Daro03002758 of Dechloromonas aromatica of 51% (gi|53730017|ref|ZP_00150562.2|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2336402..2336998	Azoarcus sp. BH72	4608715
YP_933636.1	CDS	azo2132	NC_008702.1	2337022	2337999	R	Conserved hypothetical ATPase. Homology to Daro03000733 of Dechloromonas aromatica of 64% (gi|41725756|ref|ZP_00152514.1|(NBCI ENTREZ)). Domain structure: 101 aa - 293 aa AAA-protein. InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959); AAA ATPase superfamily (IPR003593). Pfam: ATPases associated with various cellular activities. no signal peptide. no TMHS; Conserved hypothetical protein; ATPase	complement(2337022..2337999)	Azoarcus sp. BH72	4607242
YP_933637.1	CDS	folE	NC_008702.1	2338181	2338852	D	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I	2338181..2338852	Azoarcus sp. BH72	4607243
YP_933638.1	CDS	azo2134	NC_008702.1	2338856	2339185	R	Hypothetical protein, has no good homology over the entire length with hits in Database. TrEMBL Q9HT58 Hypothetical protein PA5515 [PA5515] [Pseudomonas aeruginosa. No Signal Peptide or TMH being reported as present.; Family membership; hypothetical protein	complement(2338856..2339185)	Azoarcus sp. BH72	4608821
YP_933639.1	CDS	azo2135	NC_008702.1	2339196	2340776	R	Probable low-affinity phosphate transporter protein.Involved in phosphate transport depending on the proton motive force. InterPro: Phosphate transporter family Similar to PitA a cation-phosphate transporter in E.coli. No signal peptide; High confidence in function and specificity; putative phosphate permease	complement(2339196..2340776)	Azoarcus sp. BH72	4607244
YP_933640.1	CDS	azo2136	NC_008702.1	2340834	2341187	R	Hypothetical protein ypjD. TREMBL:Q7W7V7: 56% identity, 65% similarity SPROT:YPJD_BACSU:P42979: 27% identity, 49% similarity This group of prokaryotic proteins has no known function. It includes the uncharacterized protein MazG in Escherichia coli. InterPro:IPR004518; MazG. Pfam: PF03819 No transmembrane helices (TMHMM predicted); Specificity unclear; hypothetical protein	complement(2340834..2341187)	Azoarcus sp. BH72	4607245
YP_933641.1	CDS	azo2137	NC_008702.1	2341245	2342090	R	Conserved hypothetical protein. Homology to cv2345 of C. violaceum of 54% (trembl|Q7NVJ7). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(2341245..2342090)	Azoarcus sp. BH72	4607246
YP_933642.1	CDS	azo2138	NC_008702.1	2342306	2342851	D	Hypothetical protein PA3753. A variety of bacterial transferases contain a repeat structure composed of tandem repeats of a [LIV]-G-X(4) hexapeptide, which, in the tertiary structure of LpxA (UDP N-acetylglucosamine acyltransferase) [1], has been shown to form a left-handed parallel beta helix TREMBL:Q9A526: 55% identity; 75% similarity bacterial transferase family protein. Superfamily: ferripyochelin binding protein InterPro:IPR001451; Hexapep_transf.Bacterial transferase hexapeptide repeat Pfam:PF00132; Hexapep; presence of DUF99 domain. No signal peptide (Signal P) or transmembrane helices (TMHMM).; Specificity unclear; hypothetical protein	2342306..2342851	Azoarcus sp. BH72	4607247
YP_933643.1	CDS	azo2139	NC_008702.1	2342971	2343666	D	Conserved hypothetical secreted protein. Homology to CV3305 of C.violaceum of 37% (tremble:Q7NSW4). Has PF04402, Protein of unknown function (DUF541);IPR007497:Members of this family have so far been found in bacteria and mouse SwissProt or TrEMBL entries. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs. A mouse family member has been named SIMPL (signalling molecule that associates with mouse pelle-like kinase). SIMPL appears to facilitate and/or regulate complex formation between IRAK/mPLK (IL-1 receptor-associated kinase) and IKK (inhibitor of kappa-B kinase) containing complexes, and thus regulate NF-kappa-B activity. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	2342971..2343666	Azoarcus sp. BH72	4607248
YP_933644.1	CDS	azo2140	NC_008702.1	2343704	2344009	D	Conserved hypothetical secreted protein. Homology to ebD110 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD110(KEGG)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	2343704..2344009	Azoarcus sp. BH72	4607249
YP_933645.1	CDS	azo2141	NC_008702.1	2344066	2344623	D	Conserved hypothetical secreted protein. Homology to CV2523 of Chromobacterium violaceum of 48% (trembl:Q7NV23). Pfam: NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins. Signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	2344066..2344623	Azoarcus sp. BH72	4607250
YP_933646.1	CDS	azo2142	NC_008702.1	2344733	2345164	D	Hypothetical protein MK0525 (OrfX). trembl|Q9V230 (Q9V230) Inosine-5'-monophosphate dehydrogenase related; 34% identity, 55% similarity. InterPro: CBS domain (IPR005857, IPR004840) TIGRFAM: kpsF/GutQ family TMHMM predicted absence of transmembrane helices; Specificity unclear; putative inosine-5'-monophosphate dehydrogenase related protein	2344733..2345164	Azoarcus sp. BH72	4607251
YP_933647.1	CDS	azo2143	NC_008702.1	2345219	2345494	R	Conserved hypothetical membrane protein. Homology to CV3460 of C. violaceum of 54% (trembl|Q7NSG6(SRS)). Pfam: Septum formation initiator DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2345219..2345494)	Azoarcus sp. BH72	4607252
YP_933648.1	CDS	eno	NC_008702.1	2345585	2346874	R	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase	complement(2345585..2346874)	Azoarcus sp. BH72	4607253
YP_933649.1	CDS	kdsA	NC_008702.1	2346959	2347798	R	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase	complement(2346959..2347798)	Azoarcus sp. BH72	4608670
YP_933650.1	CDS	pyrG	NC_008702.1	2347810	2349450	R	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase	complement(2347810..2349450)	Azoarcus sp. BH72	4609103
YP_933651.1	CDS	azo2147	NC_008702.1	2349604	2350314	D	Hypothetical membrane protein. No homology to the data bank. No domains predicted. Signal peptide present. TMHMM2 reporting 3 TMH present.; hypothetical protein	2349604..2350314	Azoarcus sp. BH72	4609673
YP_933652.1	CDS	sndH	NC_008702.1	2350311	2351624	R	L-sorbosone dehydrogenase. Converts L-sorbosone to 2-keto-l-gulonic acid (2kga). 63% Peptidase_M14.IPR000595; cNMP_binding. Signal peptide:present.; High confidence in function and specificity; putative L-sorbosone dehydrogenase	complement(2350311..2351624)	Azoarcus sp. BH72	4607254
YP_933653.1	CDS	acsA	NC_008702.1	2351727	2353712	R	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase	complement(2351727..2353712)	Azoarcus sp. BH72	4609879
YP_933654.1	CDS	azo2150	NC_008702.1	2353748	2354155	R	Probable Hypothetical protein AQ_1494. TREMBL:Q7WIS5: 37% identity; 51% similarity. This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT (EC: 3.1.2.23) which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl-CoA thioester hydrolases. Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. InterPro:IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No transmembrane helices TIGR00051: conserved hypothetical protein; Family membership; hypothetical protein	complement(2353748..2354155)	Azoarcus sp. BH72	4608274
YP_933655.1	CDS	etf1	NC_008702.1	2354316	2355959	D	Probable electron transfer flavoprotein-ubiquinone oxidoreductase. Homology to etfdh of H. sapiens of 57% (sprot|ETFD_HUMAN) Accepts electrons and reduces ubiquinone. Pfam: FAD_binding_3; ETF_QO no signal peptide no TMHs; electron transfer flavoprotein-ubiquinone oxidoreductase	2354316..2355959	Azoarcus sp. BH72	4607255
YP_933656.1	CDS	azo2152	NC_008702.1	2356040	2357077	R	Hypothetical secreted protein. Homology to GSU2347 of G. sulfurreducens of 26% (tremblnew|AAR35721(SRS)). Has PF04338;Protein of unknown function, DUF481; This family includes several proteins of uncharacterised function. Signal P reporting signal peptide present. NO TMH reported to be present.; hypothetical protein	complement(2356040..2357077)	Azoarcus sp. BH72	4608676
YP_933657.1	CDS	azo2153	NC_008702.1	2357201	2357677	R	Conserved hypothetical secreted protein. Homology to PP2380 of P. putida of 47% (trembl:Q88KB0). Has PF04314, Protein of unknown function (DUF461);Putative membrane or periplasmic protein. Signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(2357201..2357677)	Azoarcus sp. BH72	4607256
YP_933658.1	CDS	azo2154	NC_008702.1	2357725	2358195	R	Conserved hypothetical secreted protein. 33% similarity to TrEMBL Q8XQF8 PROBABLE SIGNAL PEPTIDE PROTEIN [RS05314] [Ralstonia solanacearum (Pseudomonas solanacearum)]. No domains predicted. Signal P reporting signal peptide present. No TMH reported being present.; Conserved hypothetical protein; hypothetical protein	complement(2357725..2358195)	Azoarcus sp. BH72	4607257
YP_933659.1	CDS	azo2155	NC_008702.1	2358192	2359436	R	Conserved hypothetical secreted protein. Homology to rsc1270 of R. solanacearum of 44% (trembl|Q8XQF7(SRS)). no domains predicted .signal peptide present. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(2358192..2359436)	Azoarcus sp. BH72	4607258
YP_933660.1	CDS	azo2156	NC_008702.1	2359411	2361702	R	TonB-dependent outer membrane receptor involved in the first step of iron internalization and metabolism. A short conserved region so called the tonB-box is present in the sequence. This domain is involved in the interaction of the receptor with the TonB protein. Similar to a E. coli iron(III) dicitrate transport protein fecA precursor. InterPro: TonB-dependent receptor protein arcC: carbamate kinase; Function unclear; TonB-dependent receptor	complement(2359411..2361702)	Azoarcus sp. BH72	4607259
YP_933661.1	CDS	azo2157	NC_008702.1	2361956	2362348	R	Conserved hypothetical secreted protein. Homology to BB1293 of Bordetella bronchiseptica of 38% (trembl:Q7WMU7). No domains predicted. Signal peptide. No TMHs; hypothetical protein	complement(2361956..2362348)	Azoarcus sp. BH72	4607260
YP_933662.1	CDS	purL	NC_008702.1	2362426	2366367	R	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase	complement(2362426..2366367)	Azoarcus sp. BH72	4607261
YP_933663.1	CDS	azo2159	NC_008702.1	2366563	2367378	D	Conserved hypothetical membrane protein. Homology to CV3583 of C. violaceum of 30% (trembl|Q7NS44(SRS)). Pfam: PAP2 superfamily no signal peptide 8 TMHs; Conserved hypothetical protein; hypothetical protein	2366563..2367378	Azoarcus sp. BH72	4609662
YP_933664.1	CDS	azo2160	NC_008702.1	2367375	2368289	D	Conserved hypothetical membrane protein. Homology to smc02385 of S. meliloti of 32% (trembl:Q92KI4). No domains predicted. Signal peptide. 6 TMHs; Conserved hypothetical protein; hypothetical protein	2367375..2368289	Azoarcus sp. BH72	4607262
YP_933665.1	CDS	azo2161	NC_008702.1	2368307	2369353	D	Glycosyltransferase,; Specificity unclear; glycosyltransferase	2368307..2369353	Azoarcus sp. BH72	4607263
YP_933666.1	CDS	azo2162	NC_008702.1	2369350	2370978	D	Hypothetical protein AQ_1704.; Family membership; glycosyltransferases	2369350..2370978	Azoarcus sp. BH72	4607264
YP_933667.1	CDS	azo2163	NC_008702.1	2370975	2371727	D	Conserved hypothetical membrane protein. Homology to Daro03001595 of Dechloromonas aromatica of 38% (gi|53730877|ref|ZP_00348993.1|(NBCI ENTREZ)). InterPro IPR008934; AcPase_VanPerase. IPR000326; PA_PTPase. Pfam PF01569; PAP2; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.023; Conserved hypothetical protein; hypothetical protein	2370975..2371727	Azoarcus sp. BH72	4607265
YP_933668.1	CDS	azo2164	NC_008702.1	2371731	2372156	R	Function unclear; hypothetical protein	complement(2371731..2372156)	Azoarcus sp. BH72	4607266
YP_933669.1	CDS	azo2165	NC_008702.1	2372204	2372563	R	Conserved hypothetical secreted protein. Homology to ebA6137 of Azoarcus sp. EbN1 of 34% (gnl|keqq|eba:ebA6137(KEGG)). No domains predicted. Signal peptide present. No TMHs Coiled Coil present.; Conserved hypothetical protein; hypothetical protein	complement(2372204..2372563)	Azoarcus sp. BH72	4607267
YP_933670.1	CDS	azo2166	NC_008702.1	2372572	2373516	R	InterPro: Peptidase family M23/M37; Specificity unclear; peptidase	complement(2372572..2373516)	Azoarcus sp. BH72	4607268
YP_933671.1	CDS	ppsA1	NC_008702.1	2373743	2376109	R	catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase	complement(2373743..2376109)	Azoarcus sp. BH72	4607269
YP_933672.1	CDS	azo2168	NC_008702.1	2376269	2377102	D	Conserved hypothetical protein. Homolog to RSC1420 of Ralstonia solanacearum of 63% (trembl:Q8XZH5). Has PF03618, Domain of unknown function (DUF299); IPR005177 ; Family of bacterial proteins with no known function. No signal peptide. No TMHs.; hypothetical protein	2376269..2377102	Azoarcus sp. BH72	4609615
YP_933673.1	CDS	azo2169	NC_008702.1	2377163	2378341	D	Conserved hypothetical secreted protein. Homology to BPP2392 of B.parapertussis of 42% (trembl:Q7W7W7). Signal P reporting signal peptide present. No TMH present. No domains predicted; Family membership; hypothetical protein	2377163..2378341	Azoarcus sp. BH72	4607270
YP_933674.1	CDS	msrB	NC_008702.1	2378368	2378784	D	Conserved hypothetical peptide methionine sulfoxide reductase. Homology to msrB of S. elongatus of 64%. Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine. InterPro: Domain of unknown function DUF25 (IPR002579). Pfam: Domain of unknown function DUF25. Tigrfam: TIGR00357: PilB-related protein. no TMHs; Family membership; peptide methionine sulfoxide reductase	2378368..2378784	Azoarcus sp. BH72	4607271
YP_933675.1	CDS	trg	NC_008702.1	2378890	2380518	D	The Trg transducer mediates chemotactic response to galactose and ribose by interacting, respectively, with sugar-occupied galactose- and ribose-binding proteins. Adaptation is linked to methylation of specific glutamyl residues of the Trg protein. Similar to sprot|MCP3_ECOLI (27%)and to TREMBL:Q88AC6. InterPro (IPR004089): Bacterial chemotaxis sensory transducer InterPro (IPR003660): HAMP InterPro (IPR004090): Methyl-accepting chemotaxis protein Pfam (PF00672): HAMP Pfam (PF00015): Methyl-accepting chemotaxis protein (MCP) signaling domain Pfam (PF05227): CHASE3 domain TMHMM reporting two TMH.; Specificity unclear; putative ribose and galactose chemoreceptor protein	2378890..2380518	Azoarcus sp. BH72	4609281
YP_933676.1	CDS	thlA	NC_008702.1	2380606	2381787	R	catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA; beta-ketothiolase	complement(2380606..2381787)	Azoarcus sp. BH72	4609968
YP_933677.1	CDS	cobD1	NC_008702.1	2381808	2382734	R	catalyzes the formation of adenosylcobinamide-phosphate from adenosylcobyric acid; CobD/CbiB family protein	complement(2381808..2382734)	Azoarcus sp. BH72	4609940
YP_933678.1	CDS	azo2174	NC_008702.1	2382839	2383312	R	Region start changed from 2383430 to 2383313 (-117 bases); hypothetical protein	complement(2382839..2383312)	Azoarcus sp. BH72	4608501
YP_933679.1	CDS	pilY1A	NC_008702.1	2383583	2386957	R	PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. Similar to trembl|Q8XW00 (31%). Pfam (PF01839): FG-GAP repeat SignalP reporting Signal peptide; Function unclear; putative type 4 pilus biogenesis protein	complement(2383583..2386957)	Azoarcus sp. BH72	4607272
YP_933680.1	CDS	azo2176	NC_008702.1	2386969	2387559	R	Hypothetical secreted protein. Homology to RS00045 of R. solanacearum of 25% (trembl|Q8XVZ9(SRS)) No domains predicted Sinal P reporting singal peptide present. No TMH being reported.; hypothetical protein	complement(2386969..2387559)	Azoarcus sp. BH72	4609579
YP_933681.1	CDS	pilW	NC_008702.1	2387559	2388581	R	In Pseudomonas aeruginosa, the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These findings increase the similarities between the fimbrial biogenesis and the Gsp-based protein-secretion supersystems. Similar to trembl|Q8XVZ8 (29%). Smart (SM00438): Repressor of transcription TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear; putative type 4 pilus biogenesis protein	complement(2387559..2388581)	Azoarcus sp. BH72	4607273
YP_933682.1	CDS	azo2178	NC_008702.1	2388592	2389143	R	Family membership; type 4 fimbrial biogenesis relatedtransmembrane protein	complement(2388592..2389143)	Azoarcus sp. BH72	4609577
YP_933683.1	CDS	azo2179	NC_008702.1	2389188	2389595	R	Probable type-4 fimbrial pilin related signal peptide protein,32% Identity to TrEMBL;Q8XVZ6,Q7NTE6. Has Signal peptide. Has COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].; hypothetical protein	complement(2389188..2389595)	Azoarcus sp. BH72	4607274
YP_933684.1	CDS	azo2180	NC_008702.1	2389690	2390103	R	In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similarity to PilE of Ralstonia eutropha (33%) TMHMM reporting one TMhelix. Pfam: pilin domain; Conserved hypothetical protein; hypothetical protein	complement(2389690..2390103)	Azoarcus sp. BH72	4607275
YP_933685.1	CDS	azo2181	NC_008702.1	2390211	2390861	R	Conserved hypothetical secreted protein. Homology to pa4048 of P. aeruginosa of 33% (trembl|Q9HWY0). no domains. signal peptide. no TMHs.; Conserved hypothetical protein; hypothetical protein	complement(2390211..2390861)	Azoarcus sp. BH72	4607276
YP_933686.1	CDS	azo2182	NC_008702.1	2390978	2391172	R	Conserved hypothetical protein. Homology to ebA5103 of Azoarcus sp. EbN1 of 57% (gnl|keqq|eba:ebA5103(KEGG)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(2390978..2391172)	Azoarcus sp. BH72	4607277
YP_933687.1	CDS	azo2183	NC_008702.1	2391193	2391678	R	putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein	complement(2391193..2391678)	Azoarcus sp. BH72	4607278
YP_933688.1	CDS	yaiE	NC_008702.1	2391697	2392020	R	Hypothetical protein,64% identical to TrEMBL;Q8XWC2 Has PF06865, Protein of unknown function (DUF1255);IPR009664 :This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown. No Signal peptide or TMH not present.; High confidence in function and specificity; hypothetical protein	complement(2391697..2392020)	Azoarcus sp. BH72	4607279
YP_933689.1	CDS	azo2185	NC_008702.1	2392036	2392263	R	Conserved hypothetical membrane protein. Homology to NMA1807 of Neisseria meningitidis of 41% (trembl|Q9JTE8(SRS)). No domains predicted. TMHMM reporting 2 TMH present. NO Signal Peptide being reported present.; Conserved hypothetical protein; hypothetical protein	complement(2392036..2392263)	Azoarcus sp. BH72	4610139
YP_933690.1	CDS	argG	NC_008702.1	2392276	2393505	R	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase	complement(2392276..2393505)	Azoarcus sp. BH72	4607280
YP_933691.1	CDS	argF	NC_008702.1	2393568	2394503	R	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase	complement(2393568..2394503)	Azoarcus sp. BH72	4608336
YP_933692.1	CDS	argD	NC_008702.1	2394503	2395693	R	catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase	complement(2394503..2395693)	Azoarcus sp. BH72	4608335
YP_933693.1	CDS	azo2189	NC_008702.1	2395933	2396217	D	Conserved hypothetical protein. Homology to bpp2544 of P. pararpertussis of 51% (TREMBL:Q7W7H5). no signal peptide. no TMHs. No domains predicted.; hypothetical protein	2395933..2396217	Azoarcus sp. BH72	4608334
YP_933694.1	CDS	rpsT	NC_008702.1	2396348	2396614	R	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20	complement(2396348..2396614)	Azoarcus sp. BH72	4607281
YP_933695.1	CDS	mviN	NC_008702.1	2396768	2398306	D	TREMBL:Q82SD5:58% identity, 69% similarity The sequencing of a number of pathogenic bacterial genomes has led to novel virulence proteins being discovered that are yet to be biochemically characterised. One example is the MviN family of proteins, first described in Salmonella [1], and conserved across a wide variety of pathogens in both animals and plants. Further work on these proteins of as yet unknown function has revealed they are integral membrane molecules, and are part of an operon essential in at least one species subcellular location:integral membrane protein (potential). similarity:belongs to the mvin family Virulence factor mviN. InterPro:IPR004268; MVIN_like. Pfam:PF03023; MVIN (Virulence factor MVIN) InterPro: Virulence factor MVIN-like TMHMM predicted 13 transmembrane helices matE: MATE efflux family protein; High confidence in function and specificity; virulence factor	2396768..2398306	Azoarcus sp. BH72	4609823
YP_933696.1	CDS	azo2192	NC_008702.1	2398320	2398643	R	Hypothetical protein, has very bad homology with hits in the database. TrEMBL;Q762H6. Has Signal Peptide.; hypothetical protein	complement(2398320..2398643)	Azoarcus sp. BH72	4609300
YP_933697.1	CDS	azo2193	NC_008702.1	2398921	2400192	D	Probable O-acetylhomoserine aminocarboxypropyltransferase. Homology to cysD of A. nidulans of 51% (sprot|CYSD_EMENI). Transforms O-acetylhomoserine into homocysteine. Pfam: Cys/Met metabolism PLP-dependent enzyme no signal peptide no TMHs; High confidence in function and specificity; O-acetylhomoserine aminocarboxypropyltransferase	2398921..2400192	Azoarcus sp. BH72	4607282
YP_933698.1	CDS	azo2194	NC_008702.1	2400229	2403828	R	Conserved hypothetical membrane protein. Homology to rs04519 of R. solanacearum of 33% (trembl|Q8Y0Z7(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2400229..2403828)	Azoarcus sp. BH72	4607283
YP_933699.1	CDS	azo2195	NC_008702.1	2403971	2405179	D	Hypothetical protein yhiN. FAD flavoproteins belong to the family of pyridine nucleotide-disulphide oxidoreductases TREMBL:Q7MBF1: 58% identity, 69% similarity InterPro: IPR001327; FAD_pyr_redox. IPR004792; HI0933_like. IPR000205; NAD_BS. IPR001100; Pyr_redox InterPro: HI0933-like protein Pfam:PF03486; HI0933_like; 1. TIGR00275: conserved hypothetical pro Non-secretory protein with signal peptide probability of 0.464 Absence of transmembrane helices (TMHMM predicted); Specificity unclear; flavoprotein	2403971..2405179	Azoarcus sp. BH72	4607284
YP_933700.1	CDS	azo2196	NC_008702.1	2405255	2406064	D	Metallo-phosphoesterase, 50% identity(67% similarity) to TrEMBL;Q6N2S9 . TrEMBL;Q885N2(53% identity). Has PF00149, Calcineurin-like phosphoesterase;IPR004843,M-pesterase:This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD P13457 or yeast MRE11 P32829. The most conserved regions in this superfamily centre around the metal chelating residues. The metallo-phosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include serine/threonine phosphatases, DNA polymerase,exonucleases, and other phosphatases. No Signal Peptide or TMH present.; Specificity unclear; metallo-phosphoesterase	2405255..2406064	Azoarcus sp. BH72	4607285
YP_933701.1	CDS	bcp2	NC_008702.1	2406216	2406671	D	Putative bacterioferritin comigratory protein. Homology to bcp of E. coli of 37% (sprot|BCP_ECOLI) InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) Pfam: AhpC/TSA family no signal peptide no TMHs; Family membership; putative bacterioferritin comigratory protein	2406216..2406671	Azoarcus sp. BH72	4607286
YP_933702.1	CDS	azo2198	NC_008702.1	2406695	2408152	D	Putative PhoH-related protein,; Conserved hypothetical protein; putative PhoH-related protein	2406695..2408152	Azoarcus sp. BH72	4608380
YP_933703.1	CDS	aer	NC_008702.1	2408503	2410050	D	Probable aerotaxis receptor protein,; High confidence in function and specificity; aerotaxis receptor	2408503..2410050	Azoarcus sp. BH72	4607287
YP_933704.1	CDS	azo2200	NC_008702.1	2410091	2411239	D	HD-domain containing protein,; Conserved hypothetical protein; HD-domain-containing protein	2410091..2411239	Azoarcus sp. BH72	4608283
YP_933705.1	CDS	azo2201	NC_008702.1	2411332	2413230	D	Putative nucleotidyltransferase,; Conserved hypothetical protein; putative nucleotidyltransferase	2411332..2413230	Azoarcus sp. BH72	4607288
YP_933706.1	CDS	azo2202	NC_008702.1	2413227	2413871	D	Probable DNA polymerase III, epsilon subunit,23% Identity to TrEMBL;Q8KDK8. Has EXOIII,SMART;SM00479;IPR006054, DnaQ;This family includes a variety of exonucleases, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.; DNA-directed DNA polymerase	2413227..2413871	Azoarcus sp. BH72	4607289
YP_933707.1	CDS	azo2203	NC_008702.1	2413954	2414493	D	InterPro: NLP/P60; Family membership; putative lipoprotein precusor	2413954..2414493	Azoarcus sp. BH72	4607290
YP_933708.1	CDS	azo2204	NC_008702.1	2414546	2414887	R	Conserved hypothetical protein. Homology to CV2970 of C.violaceum of 42% (trembl:Q7NTT3). No domains predicted. No TMHs. No signal peptide.; Function unclear; hypothetical protein	complement(2414546..2414887)	Azoarcus sp. BH72	4607291
YP_933709.1	CDS	fbpA1	NC_008702.1	2415014	2416036	D	Iron (III)-transport system, substrate-binding protein FbpA. Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import.Iron(III)periplasmic binding protein component.; High confidence in function and specificity; putative iron transport system substrate-binding protein	2415014..2416036	Azoarcus sp. BH72	4607292
YP_933710.1	CDS	fbpB1	NC_008702.1	2416091	2417758	R	Iron(III)-transport system permease fbpB 2. Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Probably responsible for the translocation of the substrate across the membrane (By similarity). pts-Glc: PTS system maltose and gluco; High confidence in function and specificity; iron (III) transport system permease	complement(2416091..2417758)	Azoarcus sp. BH72	4608730
YP_933711.1	CDS	fbpC1	NC_008702.1	2417875	2418999	D	Ferric cations import ATP-binding protein fbpC 2 (EC 3.6.3.30). Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Responsible for energy coupling to the transport system (By similarity). InterPro: AAA ATPase superfamily apsK: adenylylsulfate kinase; Specificity unclear; putative iron (III) transport system ATP-binding protein	2417875..2418999	Azoarcus sp. BH72	4608732
YP_933712.1	CDS	aat	NC_008702.1	2418999	2419706	D	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase	2418999..2419706	Azoarcus sp. BH72	4608733
YP_933713.1	CDS	ate	NC_008702.1	2419667	2420506	D	Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase	2419667..2420506	Azoarcus sp. BH72	4608244
YP_933714.1	CDS	pyrD	NC_008702.1	2420577	2421593	D	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2	2420577..2421593	Azoarcus sp. BH72	4608363
YP_933715.1	CDS	xdhA	NC_008702.1	2421804	2423330	D	Xanthine dehydrogenase (subunit A) oxidoreductase protein; High confidence in function and specificity; xanthine dehydrogenase	2421804..2423330	Azoarcus sp. BH72	4609670
YP_933716.1	CDS	xdhB	NC_008702.1	2423317	2425656	D	Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity; xanthine dehydrogenase	2423317..2425656	Azoarcus sp. BH72	4610124
YP_933717.1	CDS	xdhC	NC_008702.1	2425667	2426761	D	xanthine dehydrogenase, probable (chaperone); High confidence in function and specificity; putative xanthine dehydrogenase	2425667..2426761	Azoarcus sp. BH72	4610125
YP_933718.1	CDS	azo2214	NC_008702.1	2426758	2428323	D	Conserved hypothetical sugar transporter ATP-binding protein. Homology to orf96 of P. sp strain ADP of 65% (TREMBL:Q936X7). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR sugars. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: AAA-ATPase; ABC transporter. no signal peptide. no TMHs; Specificity unclear; hypothetical protein	2426758..2428323	Azoarcus sp. BH72	4610126
YP_933719.1	CDS	azo2215	NC_008702.1	2428310	2429374	D	Conserved hypothetical ABC transporter permease. Homology to orf95 of Pseudomonas sp strain ADP of 57% (trembl|Q936X8). Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851). Pfam: Branched-chain ammino acid transporter/permease component. no signal peptide. 9 TMHs; Specificity unclear; ABC transporter permease	2428310..2429374	Azoarcus sp. BH72	4607293
YP_933720.1	CDS	azo2216	NC_008702.1	2429377	2430309	D	TREMBL:Q8XXD9: 46% identity, 59% similarity Hypothetical protein MG120 homolog (A65_orf517). Bacterial inner-membrane translocator.The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown [3, 4] that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity InterPro:IPR001851; Bac_inmem_transp. Pfam:PF02653; BPD_transp_2 gntP: gluconate transporter TMH's 9 (TMHMM predicted); Specificity unclear; ABC transporter permease	2429377..2430309	Azoarcus sp. BH72	4607294
YP_933721.1	CDS	azo2217	NC_008702.1	2430582	2432618	D	Similar to FecA, ferric-citrate outer membrane receptor in E.coli, involved in the recognition and internalization of ferric-citrate. InterPro: TonB-dependent receptor protein; Function unclear; putative TonB-dependent receptor	2430582..2432618	Azoarcus sp. BH72	4607295
YP_933722.1	CDS	cbiK	NC_008702.1	2432622	2433353	D	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the putative periplasmic-binding protein CbiK precursor in A.pleuropneumoniae. thiE: thiamine-phosphate pyrophosphoryla; High confidence in function and specificity; putative cobalt transport system periplasmic-binding protein	2432622..2433353	Azoarcus sp. BH72	4607296
YP_933723.1	CDS	azo2219	NC_008702.1	2433350	2433829	D	Conserved hypothetical membrane protein. Homology to cbiL of Actinobacillus pleuropneumoniae of 39% (gi|5733705|gb|AAD49725.1|(NBCI ENTREZ)). Signal P reproting signal peptide present. TMHMM reporting TMH present.; Conserved hypothetical protein; hypothetical protein	2433350..2433829	Azoarcus sp. BH72	4608430
YP_933724.1	CDS	cbiM	NC_008702.1	2433832	2434458	D	catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM	2433832..2434458	Azoarcus sp. BH72	4607297
YP_933725.1	CDS	cbiQ	NC_008702.1	2434455	2435144	D	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae.; Function unclear; putative cobalt transport system permease	2434455..2435144	Azoarcus sp. BH72	4608432
YP_933726.1	CDS	cbiO	NC_008702.1	2435203	2435838	D	Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1.; High confidence in function and specificity; putative cobalt transport system ATP-binding protein	2435203..2435838	Azoarcus sp. BH72	4608434
YP_933727.1	CDS	guaD	NC_008702.1	2435887	2437182	D	Catalyzes the deamination of guanine; guanine deaminase	2435887..2437182	Azoarcus sp. BH72	4608433
YP_933728.1	CDS	yaiI	NC_008702.1	2437170	2437643	D	Hypothetical protein yaiI,58% identical (75% similar) to SwissProt; P52088, of E.coli.SwissProt;Q8XEM1(61% identity) TrEMBL; Q8ED72. Has PF02639, Uncharacterized BCR, YaiI/YqxD family COG1671;IPR003791. No Signal peptide or TMH present.; YaiI/YqxD family protein	2437170..2437643	Azoarcus sp. BH72	4608963
YP_933729.1	CDS	azo2225	NC_008702.1	2437796	2439499	D	GGDEF/EAL/PAS-domain containing protein; diguanylate cyclase	2437796..2439499	Azoarcus sp. BH72	4610140
YP_933730.1	CDS	azo2226	NC_008702.1	2439509	2440297	R	Probable N-acetylmuramoyl-L-alanine amidase amiA precursor, 28% identity to TrEMBL;Q823N1. 26% identity to SwissProt;P36548 Has SMART;SM00646, Ami_3. Signal Peptide present. Has PF01520; N-acetylmuramoyl-L-alanine amidase ;IPR002508 Amidase_3_hydro; This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls.; N-acetylmuramoyl-L-alanine amidase	complement(2439509..2440297)	Azoarcus sp. BH72	4607298
YP_933731.1	CDS	azo2227	NC_008702.1	2440284	2442953	R	GGDEF/EAL/PAS-domain containing protein; diguanylate cyclase	complement(2440284..2442953)	Azoarcus sp. BH72	4607299
YP_933732.1	CDS	azo2228	NC_008702.1	2442950	2443813	R	Conserved hypothetical amino acid-binding protein. Homology to bb2160 of B. bronchiseptica of 39% (trembl|Q7WKE7). PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR AN AMINO ACID. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001311). Pfam: Bacterial extracellular solute-binding protein. Signal peptide. no TMHs; Family membership; amino acid-binding protein	complement(2442950..2443813)	Azoarcus sp. BH72	4607300
YP_933733.1	CDS	azo2229	NC_008702.1	2443996	2444244	D	Conserved hypothetical secreted protein. Homology to PSPTO5169 of P.syringae 45% (tremble:Q87UX3). No domains predicted. Signal P reporting Signal Peptide present. No TMH being reported as present.; Conserved hypothetical protein; hypothetical protein	2443996..2444244	Azoarcus sp. BH72	4607301
YP_933734.1	CDS	azo2230	NC_008702.1	2444384	2444647	D	Conserved hypothetical membrane protein. Homology to pp2721 of P. putida of 56% (trembl|Q88JC8(SRS). no domains predicted. no signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	2444384..2444647	Azoarcus sp. BH72	4607302
YP_933735.1	CDS	azo2231	NC_008702.1	2444681	2445784	R	Mannose-1-phosphate guanyltransferase involved in the reaction:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDPmannose. 51% Hexapep_transf.IPR005835; NTP_transferase. Pfam:PF00132; Hexapep; 2.PF00483; NTP_transferase; 1.; High confidence in function and specificity; putative mannose-1-phosphate guanylyltransferase	complement(2444681..2445784)	Azoarcus sp. BH72	4607303
YP_933736.1	CDS	udgH	NC_008702.1	2445816	2447138	R	61% UDPG_MGDP_dh. Pfam:PF00984; UDPG_MGDP_dh; 1.PF03720; UDPG_MGDP_dh_C; 1.PF03721; UDPG_MGDP_dh_N; 1. Signal peptide: present.; High confidence in function and specificity; putative UDP-glucose 6-dehydrogenase	complement(2445816..2447138)	Azoarcus sp. BH72	4607304
YP_933737.1	CDS	gumM	NC_008702.1	2447180	2447938	R	60% WecB_TagA_CpsF. Pfam:PF03808; Glyco_tran_WecB; 1. TIGRFAMs:TIGR00696; wecB_tagA_cpsF; 1. Non-secretory protein.; High confidence in function and specificity; putative glycosyltransferase	complement(2447180..2447938)	Azoarcus sp. BH72	4610063
YP_933738.1	CDS	gumJ	NC_008702.1	2447961	2449433	R	25% Polysacc_synt. Pfam:PF01943; Polysacc_synt; 1. TMhelix:14. Non-secretory protein.; Family membership; putative polysaccharide translocase	complement(2447961..2449433)	Azoarcus sp. BH72	4608973
YP_933739.1	CDS	gumK	NC_008702.1	2449543	2450694	R	64%; High confidence in function and specificity; putative glucuronyl transferase	complement(2449543..2450694)	Azoarcus sp. BH72	4608971
YP_933740.1	CDS	eglA	NC_008702.1	2450726	2451748	R	41% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1. Signal peptide: present.; High confidence in function and specificity; putative endoglucanase	complement(2450726..2451748)	Azoarcus sp. BH72	4608972
YP_933741.1	CDS	gumH	NC_008702.1	2451745	2452860	R	60% Glyco_trans_1. Pfam:PF00534; Glycos_transf_1; 1.; Specificity unclear; putative glycosyltransferase	complement(2451745..2452860)	Azoarcus sp. BH72	4608663
YP_933742.1	CDS	gumE	NC_008702.1	2452857	2454176	R	26%; Family membership; putative surface polysaccharide polymerase	complement(2452857..2454176)	Azoarcus sp. BH72	4608970
YP_933743.1	CDS	gumF	NC_008702.1	2454178	2455266	R	44% Acyl_transf_3. Pfam:PF01757; Acyl_transf_3; 1. TMhelix:9. Non-secretory protein.; High confidence in function and specificity; putative acetyltransferase	complement(2454178..2455266)	Azoarcus sp. BH72	4608968
YP_933744.1	CDS	wzc1	NC_008702.1	2455235	2456101	R	Tyrosine-protein kinase wzc (EC 2.7.10.1). Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). gidA: glucose-inhibited division prot; High confidence in function and specificity; tyrosine-protein kinase	complement(2455235..2456101)	Azoarcus sp. BH72	4608969
YP_933745.1	CDS	gumC	NC_008702.1	2456144	2457553	R	21% LPS_Wzz_MPA. Pfam:PF02706; Wzz; 1. TMhelix:1. Signal peptide:present.; High confidence in function and specificity; putative exopolysaccharide biosynthesis protein	complement(2456144..2457553)	Azoarcus sp. BH72	4610118
YP_933746.1	CDS	gumB	NC_008702.1	2457567	2458376	R	Putative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present.; Family membership; putative polysaccharide export protein	complement(2457567..2458376)	Azoarcus sp. BH72	4608966
YP_933747.1	CDS	azo2243	NC_008702.1	2458429	2459328	R	Conserved hypothetical secreted protein. Homology to TdenA01000001 of Thiobacillus denitrificans of 33% (gi|52007706|ref|ZP_00335083.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(2458429..2459328)	Azoarcus sp. BH72	4608965
YP_933748.1	CDS	azo2244	NC_008702.1	2459330	2459746	R	Hypothetical secreted protein. No homology to the data bank. No domains pedicted. No TMHs signal peptide; hypothetical protein	complement(2459330..2459746)	Azoarcus sp. BH72	4607305
YP_933749.1	CDS	azo2245	NC_008702.1	2459794	2460981	R	Hypothetical secreted protein. No good homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(2459794..2460981)	Azoarcus sp. BH72	4607306
YP_933750.1	CDS	gumD	NC_008702.1	2461174	2462565	D	43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5.; Specificity unclear; putative glycosyltransferase	2461174..2462565	Azoarcus sp. BH72	4607307
YP_933751.1	CDS	azo2247	NC_008702.1	2462824	2464230	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	2462824..2464230	Azoarcus sp. BH72	4608967
YP_933752.1	CDS	azo2248	NC_008702.1	2464264	2464395	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2464264..2464395)	Azoarcus sp. BH72	4607308
YP_933753.1	CDS	azo2249	NC_008702.1	2464506	2465156	D	Region start changed from 2464498 to 2464507 (-9 bases); putative DNA polymerase-like protein	2464506..2465156	Azoarcus sp. BH72	4607309
YP_933754.1	CDS	thmS1	NC_008702.1	2465256	2466758	R	probable succinate semialdehyde dehydrogenase [NAD(P)+). Homology to thmS of Pseudonocardia sp. K1 of 55% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership; succinate semialdehyde dehydrogenase	complement(2465256..2466758)	Azoarcus sp. BH72	4607310
YP_933755.1	CDS	azo2251	NC_008702.1	2467221	2467694	R	Hypothetical protein, 30% identiy(50% similarity) to TrEMBL;Q8FYJ1. TrEMBL;Q8YJA6. Has (IPR010755)PF07049,Protein of unknown function (DUF1332);This family consists of several hypothetical bacterial proteins of around 165 residues in length. The function of this family is unknown. No Signal peptide or TMH present.; Function unclear; hypothetical protein	complement(2467221..2467694)	Azoarcus sp. BH72	4609941
YP_933756.1	CDS	azo2252	NC_008702.1	2467705	2468685	R	Conserved hypothetical BNR domain protein. Homology to pa3080 of P. aeruginosa of 38% (trembl|Q9HZC8). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear; hypothetical protein	complement(2467705..2468685)	Azoarcus sp. BH72	4607311
YP_933757.1	CDS	azo2253	NC_008702.1	2468697	2471060	R	Putative membrane protein MJ1562. TREMBL:Q88J37: 52% identity, 66% similarity InterPro:IPR001036; Acrflvin_res. IPR000731; SSD_5TM Pfam:Patched:Patched family 2A067: efflux transporter putative Presence of signal peptide (Signal P predicted). Transmembrane helices 12 (TMHMM predicted); Family membership; RND efflux transporter	complement(2468697..2471060)	Azoarcus sp. BH72	4607312
YP_933758.1	CDS	azo2254	NC_008702.1	2471191	2472987	R	Conserved hypothetical secreted protein. Homology to PP2811 of P.putida of 32% (tremble:Q88J38). Has PF06980;Protein of unknown function (DUF1302)domain;IPR010727 This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMH reported.; Conserved hypothetical protein; hypothetical protein	complement(2471191..2472987)	Azoarcus sp. BH72	4607313
YP_933759.1	CDS	azo2255	NC_008702.1	2473019	2474398	R	Conserved hypothetical secreted protein. Homology to PA3081 of P.aeruginosa of 43% (trembl:Q9HZC7). Has pfam07044, DUF1329, Protein of unknown function (DUF1329). IPR010752; This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. Signal Peptide present. No TMH being reported.; Conserved hypothetical protein; hypothetical protein	complement(2473019..2474398)	Azoarcus sp. BH72	4607314
YP_933760.1	CDS	azo2256	NC_008702.1	2474463	2474945	R	Conserved hypothetical cytochrome c-552. Homology to Bcepa03004834 of Burkholderia cepacia of 38% (gi|46313246|ref|ZP_00213837.1|(NBCI ENTREZ)). InterPro: Cytochrome c class I (IPR003088). Pfam: cytochrome c. probable signal peptide. no TMHS; Conserved hypothetical protein; cytochrome c-552	complement(2474463..2474945)	Azoarcus sp. BH72	4607315
YP_933761.1	CDS	mauA	NC_008702.1	2474953	2475486	R	Probable methylamine dehydrogenase. Homology to mauD of P. denifrificans of 45% (CAA67190) carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. InterPro: Methylamine dehydrogenase L subunit (IPR004229) Pfam: Methylamine dehydrogenase, L chain signal peptide no TMHs; High confidence in function and specificity; methylamine dehydrogenase, L chain	complement(2474953..2475486)	Azoarcus sp. BH72	4607316
YP_933762.1	CDS	mauD	NC_008702.1	2475508	2476110	R	Probable methylamine utilization protein. My be specifically involved in the processing transport and/or maturation of the methylamine dehydrogenase beta-subunit. Tigrfam: dsbE: periplasmic protein thiol:disulfide Signal peptide probable 1 TMHs; Family membership; methylamine utilization protein mauD	complement(2475508..2476110)	Azoarcus sp. BH72	4609196
YP_933763.1	CDS	mauE	NC_008702.1	2476107	2476658	R	Methylamine utilization protein mauE. Homology to mauE of M. extorquens of 37% (sprot|MAUE_METEX) MAY BE SPECIFICALLY INVOLVED IN THE PROCESSING TRANSPORT AND/OR MATURATION OF THE MADH BETA-SUBUNIT. no signal peptide probable 4 TMHs; Family membership; putative methylamine utilization protein MauE	complement(2476107..2476658)	Azoarcus sp. BH72	4609198
YP_933764.1	CDS	maub	NC_008702.1	2476658	2477812	R	Methylamine dehydrogenase heavy chain precursor (MADH):- Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Entry name SWISSPROT:DHMH_METEX Prim. accession # Q49124 Identities = 100/339 (29%) Prediction: Signal peptide Signal peptide probability: 1.000 Number of predicted TMHs: 0; Family membership; putative methylamine dehydrogenase heavy chain	complement(2476658..2477812)	Azoarcus sp. BH72	4609199
YP_933765.1	CDS	eutR	NC_008702.1	2478283	2479272	D	Putative ethanolamine operon transcriptional regulator,; Family membership; putative ethanolamine operon transcriptional regulator	2478283..2479272	Azoarcus sp. BH72	4609197
YP_933766.1	CDS	pdhR	NC_008702.1	2479608	2480288	D	Putative pyruvate dehydrogenase complex repressor,; Family membership; putative pyruvate dehydrogenase complex repressor	2479608..2480288	Azoarcus sp. BH72	4608688
YP_933767.1	CDS	azo2263	NC_008702.1	2480340	2481158	D	Putative amino acid-binding protein. Homology to fliy of E. coli of 26% (AAC43545). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR1638); solute binding protein/glutamte receptor (IPR001311) Pfam: Bacterial extracellular solute-binding protein signal peptide no TMHS hisG: ATP phosphoribosyltransferase; Specificity unclear; putative amino acid-binding protein	2480340..2481158	Azoarcus sp. BH72	4609515
YP_933768.1	CDS	azo2264	NC_008702.1	2481229	2481897	D	Amino acid ABC transporter permease, 75% Identity to TrEMBL;Q87UQ0, 65% Identity to TrEMBL;Q8XXK9,Q6F6T8. Has PF00528; IPR000515, BPD_transp; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity. This region seems to be located in a cytoplasmic loop between two transmembrane domains. Apart from the conserved region,the sequence of these proteins is quite divergent, and they have a variable number of transmembrane helices,however they can be classified into seven families which have been respectively termed: araH, cysTW, fecCD, hisMQ,livHM, malFG and oppBC. Has PROSITE;PS50928; ABC_TM1; amino acid ABC transporter permease	2481229..2481897	Azoarcus sp. BH72	4607317
YP_933769.1	CDS	azo2265	NC_008702.1	2481897	2482550	D	Conserved hypothetical amino acid permease. Homology to pspto5247 of P. syringae (trembl|Q87UP9). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE (BY SIMILARITY). Interpro: binding-protein-depenent transport system inner membrane component (IPR000515). Pfam: Binding-protein-dependent transport system. no signal peptide. 3 TMHs; Specificity unclear; amino acid permease	2481897..2482550	Azoarcus sp. BH72	4607318
YP_933770.1	CDS	glnQ2	NC_008702.1	2482537	2483265	D	Probable glutamine transport ATP-binding protein. Homology with glnQ of B. stearothermophilus of 53% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_Transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity; glutamine transport ATP-binding protein	2482537..2483265	Azoarcus sp. BH72	4607319
YP_933771.1	CDS	gstB	NC_008702.1	2483290	2483919	R	Probable Glutathione transferase. Homology to gstB of P. mirablilis of 29% (sprot|GT_PROMI). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. InterPro: Glutathione S-transferase N terminus(IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; Family membership; putative glutathione transferase	complement(2483290..2483919)	Azoarcus sp. BH72	4608903
YP_933772.1	CDS	azo2268	NC_008702.1	2484151	2484591	D	Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	2484151..2484591	Azoarcus sp. BH72	4608958
YP_933773.1	CDS	azo2269	NC_008702.1	2484632	2485495	D	Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership; hypothetical protein	2484632..2485495	Azoarcus sp. BH72	4607320
YP_933774.1	CDS	azo2270	NC_008702.1	2485527	2487548	R	Methyl-accepting chemotaxis transducer,; Specificity unclear; methyl-accepting chemotaxis transducer	complement(2485527..2487548)	Azoarcus sp. BH72	4607321
YP_933775.1	CDS	azo2271	NC_008702.1	2487857	2488717	D	Conserved hypothetical protein. Homology to Daro03003250 of Dechloromonas aromatica of 32% (gi|41723264|ref|ZP_00150207.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	2487857..2488717	Azoarcus sp. BH72	4607322
YP_933776.1	CDS	kup	NC_008702.1	2488755	2490671	R	Low affinity potassium transport system protein,Kup. In E.coli, Kup has two domains, the first aa residues form an integral membrane domain and the C-terminal residues form a hydrophilic ones located at the citoplasmic side of the membrane. Kup: involved in potassium uptake and metabolism.; High confidence in function and specificity; putative potassium uptake protein	complement(2488755..2490671)	Azoarcus sp. BH72	4607323
YP_933777.1	CDS	azo2273	NC_008702.1	2490788	2491693	R	Conserved hypothetical protein:- Entry name:-TREMBL:Q89MA9 Prim. accession # Q89MA9 InterPro:-IPR000379; Ser_estrs. Identities = 120/294 (40%) Pfam:-Thioesterase domain Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; hypothetical protein	complement(2490788..2491693)	Azoarcus sp. BH72	4609108
YP_933778.1	CDS	sbp1	NC_008702.1	2491893	2492903	R	Sulfate-binding protein precursor, Sbp. E.coli Sulfate starvation-induced protein 2,SSI2. This protein specifically binds sulfate and is involved in its transmembrane transport. InterPro: Prokaryotic sulfate- /thiosulfate-binding protein. In other bacteria Sbp is a periplasmic component of an ABC transport system. TIGR00363: lipoprotein YaeC family Signal peptide; High confidence in function and specificity; putative sulfate-binding protein	complement(2491893..2492903)	Azoarcus sp. BH72	4607324
YP_933779.1	CDS	azo2275	NC_008702.1	2493040	2493828	R	Hypothetical protein ycjL. TREMBL:Q890B8: 38% identity, 53% similarity. Glutamine amidotransferase activity involves the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a pecific substrate, thus creating a new carbon-nitrogen group on the substrate. InterPro:IPR000991; GATase_1 PROSITE PS00442 GATASE_TYPE_I BLOCKS: BL00442 PFAM:PF00117 GATase; PF00310 GATase_2 trpG_papA: glutamine amidotransferase o No signal peptide (SignalP predicted) No transmembrane helices; High confidence in function and specificity; putative glutamine amidotransferase	complement(2493040..2493828)	Azoarcus sp. BH72	4609841
YP_933780.1	CDS	ybdK	NC_008702.1	2493825	2494952	R	ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase	complement(2493825..2494952)	Azoarcus sp. BH72	4607325
YP_933781.1	CDS	azo2277	NC_008702.1	2494949	2496157	R	Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family. No signal peptide. 12 TMHs.; Conserved hypothetical protein; Na/H antiporter	complement(2494949..2496157)	Azoarcus sp. BH72	4610145
YP_933782.1	CDS	azo2278	NC_008702.1	2496728	2498482	D	Conserved hypothetical protein. Homology to pa3943 of P. aeruginosa (TREMBL:Q9HX73). no domians predicted. weak evidence for signal peptide. no TMHs; hypothetical protein	2496728..2498482	Azoarcus sp. BH72	4607326
YP_933783.1	CDS	azo2279	NC_008702.1	2498525	2499364	D	Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure. No signal peptide. No TMHs.; hypothetical protein	2498525..2499364	Azoarcus sp. BH72	4607327
YP_933784.1	CDS	azo2280	NC_008702.1	2499372	2499698	D	Hypothetical protein 25% Identity to TrEMBL;Q7U749. No domains, repeats, motifs or features present; hypothetical protein	2499372..2499698	Azoarcus sp. BH72	4607328
YP_933785.1	CDS	nifF2	NC_008702.1	2499793	2500329	D	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA	2499793..2500329	Azoarcus sp. BH72	4607329
YP_933786.1	CDS	azo2282	NC_008702.1	2500478	2503111	D	Conserved hypothetical protein. Identity to Daro_1071 of Dechloromonas aromatica of 41% (gi|71846331|gb|AAZ45827.1|). Pfam: CheW-like domain. CheW-like domain proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.; hypothetical protein	2500478..2503111	Azoarcus sp. BH72	4609362
YP_933787.1	CDS	azo2283	NC_008702.1	2503186	2503836	D	Similar to TREMBL:Q92PT6 (40% identical); TREMBL:Q98MM5 (39% identical).; hypothetical protein	2503186..2503836	Azoarcus sp. BH72	4607330
YP_933788.1	CDS	azo2284	NC_008702.1	2503871	2504842	R	Similar to TREMBL:Q9RBR1 (43% identity); TREMBL:Q8GN85 (42% identity); TREMBL:Q87NF7 (23% identity). SignalP predicting signal peptide.; Specificity unclear; putative periplasmic substrate binding protein	complement(2503871..2504842)	Azoarcus sp. BH72	4607331
YP_933789.1	CDS	dctM3	NC_008702.1	2504880	2506196	R	The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 38% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. Signal peptide:present. TMhelix:11.; Specificity unclear; putative TRAP-type C4-dicarboxylate transport system large permease	complement(2504880..2506196)	Azoarcus sp. BH72	4607332
YP_933790.1	CDS	dctQ3	NC_008702.1	2506198	2506716	R	TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate.40% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:3.; Function unclear; putative TRAP-type C4-dicarboxylate transport system small permease	complement(2506198..2506716)	Azoarcus sp. BH72	4608599
YP_933791.1	CDS	azo2287	NC_008702.1	2506856	2507242	R	Conserved hypothetical protein. Homology to tll1086 of T.elongatus of 62% (trembl:Q8DJY4). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2506856..2507242)	Azoarcus sp. BH72	4608610
YP_933792.1	CDS	azo2288	NC_008702.1	2507315	2508640	R	HD-domain containing protein,; Conserved hypothetical protein; HD-domain-containing protein	complement(2507315..2508640)	Azoarcus sp. BH72	4607333
YP_933793.1	CDS	azo2289	NC_008702.1	2509010	2509729	D	Mg(2+) transport ATPase [mgtC family protein], 35% identity(54% similarity) to TrEMBL;Q7NTN3. Has PF02308,MgtC family;(IPR003416, MgtCSapB_transpt);The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known, but it is thought that MgtC may act as an accessory protein for MgtB, thus mediating magnesium influx into the cytosol. Also included in this family are the Bacillus subtilis SapB protein and several hypothetical proteins. NO Signal Peptide or TMH present.; Family membership; putative transport ATPase	2509010..2509729	Azoarcus sp. BH72	4610018
YP_933794.1	CDS	azo2290	NC_008702.1	2509855	2510652	D	Conserved hypothetical protein. Homology to hypothetical protein all0327 of Anabaena sp. of 52%. no signal peptid. no TMHs. No domains predicted.; hypothetical protein	2509855..2510652	Azoarcus sp. BH72	4607335
YP_933795.1	CDS	tfoX	NC_008702.1	2510662	2511024	D	Conserved hypothetical DNA transformation protein,; Conserved hypothetical protein; DNA transformation protein	2510662..2511024	Azoarcus sp. BH72	4607336
YP_933796.1	CDS	ada	NC_008702.1	2511136	2512284	D	Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity; methylated-DNA--[protein]-cysteine S-methyltransferase	2511136..2512284	Azoarcus sp. BH72	4609931
YP_933797.1	CDS	alkB	NC_008702.1	2512299	2512964	D	Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity; DNA-directed DNA polymerase	2512299..2512964	Azoarcus sp. BH72	4608277
YP_933798.1	CDS	azo2294	NC_008702.1	2513048	2514142	D	Putative Zinc carboxypeptidase-related protein, 45% identity to TrEMBL;Q6MKH4,Zinc carboxypeptidase-related protein (EC 3.4.17.-) [Bd2418] [Bdellovibrio bacteriovorus] Has pfam00246, Zn_carbOpept, Zinc carboxypeptidase domain.; High confidence in function and specificity; carboxypeptidase A	2513048..2514142	Azoarcus sp. BH72	4608303
YP_933799.1	CDS	azo2295	NC_008702.1	2514180	2514956	D	TREMBL:Q8EFJ6: 33% identity, 47% similarity. Probable Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). Interpro:IPR000073; A/b_hydrolase (alpha/beta fold family). IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 2a75: L-lysine exporter; Function unclear; putative hydrolase	2514180..2514956	Azoarcus sp. BH72	4607337
YP_933800.1	CDS	phhB	NC_008702.1	2515151	2515504	D	PHS (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD). InterPro: Pterin 4 alpha carbinolamine dehydratase; High confidence in function and specificity; 4a-hydroxytetrahydrobiopterin dehydratase	2515151..2515504	Azoarcus sp. BH72	4607338
YP_933801.1	CDS	azo2297	NC_008702.1	2515532	2515825	D	Conserved hypothetical protein. Homology to RS05664 of R.solanacearum of 53% (trembl:Q8XQC7). No domains predicted. No signal peptide or TMH reported present.; hypothetical protein	2515532..2515825	Azoarcus sp. BH72	4609548
YP_933802.1	CDS	azo2298	NC_008702.1	2515850	2516959	D	Conserved hypothetical protein. Homology to PA1356 of Pseudomonas aeruginosa of 69% (trembl|Q9I3Y8(SRS)). No domains predicted. No signal peptide or TMH reported to be present.; hypothetical protein	2515850..2516959	Azoarcus sp. BH72	4607339
YP_933803.1	CDS	aidB1	NC_008702.1	2516981	2518624	D	Aidb protein:-belongs to the acyl-coa dehydrogenase family. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name SWISSPROT:AIDB_ECOLI Prim. accession # P33224 Identities = 257/515 (49%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1 Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; acyl-CoA dehydrogenase	2516981..2518624	Azoarcus sp. BH72	4607340
YP_933804.1	CDS	azo2300	NC_008702.1	2519006	2520262	D	Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 65% (trembl|Q9F206(SRS)). Pfam: Protein of unknown function (DUF1504). This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown. signal peptide. 10 TMHs; Conserved hypothetical protein; hypothetical protein	2519006..2520262	Azoarcus sp. BH72	4608289
YP_933805.1	CDS	gspE3	NC_008702.1	2520561	2522381	D	General secretion pathway protein E,; Specificity unclear; general secretory pathway protein E	2520561..2522381	Azoarcus sp. BH72	4607341
YP_933806.1	CDS	azo2302	NC_008702.1	2522542	2523762	D	Conserved hypothetical protein. Homology to Mll6421 of M.loti of 37% (trembl:Q989H3). Has PF02661, Fic protein family;IPR003812:This family consists of the Fic (filamentation induced by cAMP) protein and its relatives. The Fic protein is involved in cell division and is suggested to be involved in the synthesis of PAB or folate, indicating that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members. The exact molecular function of these proteins is uncertain. No signal peptide or TMH present.; hypothetical protein	2522542..2523762	Azoarcus sp. BH72	4608951
YP_933807.1	CDS	azo2303	NC_008702.1	2523759	2525189	R	Conserved hypothetical membrane protein. Homology to Daro03002720 of Dechloromonas aromatica of 55% (gi|41723618|ref|ZP_00150528.1|(NBCI ENTREZ)). Permease,member of the Major Facilitator Superfamiliy (MFS)transporters.MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Similar to proteins involved in tetracycline resistance. Hypothetical transport protein yhcA, from B.subtilis. InterPro: Drug resistance transporter EmrB/QacA subfamily efflux_EmrB: drug resistance transport. Signal peptide predicted. 13 TMHs; Function unclear; hypothetical protein	complement(2523759..2525189)	Azoarcus sp. BH72	4607342
YP_933808.1	CDS	azo2304	NC_008702.1	2525577	2526161	R	Transcriptional regulator, MerR-family InterPro: Bacterial regulatory protein, MerR, Putative DNA binding HTH reporting nucleic acid binding motif; MerR family transcriptional regulator	complement(2525577..2526161)	Azoarcus sp. BH72	4607343
YP_933809.1	CDS	azo2305	NC_008702.1	2526158	2526574	R	Conserved hypothetical protein. Homology to CV1954 of Chromobacterium violaceum of 33% (trembl:Q7NWM9). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2526158..2526574)	Azoarcus sp. BH72	4607344
YP_933810.1	CDS	azo2306	NC_008702.1	2526840	2527454	D	Tyrosine recombinase xerD. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex xerD specifically exchanges the bottom DNA strands (By similarity). InterPro: Phage integrase; Specificity unclear; putative tyrosine recombinase xerD	2526840..2527454	Azoarcus sp. BH72	4607345
YP_933811.1	CDS	azo2307	NC_008702.1	2527848	2531426	D	Hypothetical protein, 39% similarity to TrEMBL;Q8Z0Z1. No Signal Peptide or TMH present. TIGR00090: iojap-related protein; hypothetical protein	2527848..2531426	Azoarcus sp. BH72	4607346
YP_933812.1	CDS	azo2308	NC_008702.1	2531423	2537752	D	Hypothetical protein yjiV. TREMBL:Q8XC75: 33% identity, 49% similarity InterPro: IPR001410;DEAD/DEAH box helicase IPR001650; Helicase_C. Pfam: PF00270; DEAD; 1. PF00271; Helicase_C; 1. SMART: SM00487; DEXDc; 1. SM00490; HELICc L18_bact: ribosomal protein L18 No signal peptide No transmembrane helices; High confidence in function and specificity; putative helicase related protein	2531423..2537752	Azoarcus sp. BH72	4607347
YP_933813.1	CDS	azo2309	NC_008702.1	2537814	2538605	D	Conserved hypothetical protein. 61% identity to hypothetical protein Bucepa02000624 [Burkholderia cepacia R1808] (gi|46324486|ref|ZP_00224847.1|(NBCI ENTREZ)). NO Signal peptide or TMH reported present. no domains predicted; hypothetical protein	2537814..2538605	Azoarcus sp. BH72	4607348
YP_933814.1	CDS	palZ	NC_008702.1	2538956	2540617	R	Alpha -D-1,4-glucosidase, PalZ. Involved in the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. 55% Alpha_amyl_cat.IPR006589; Alp_amyl_cat_sub.IPR006046; Glyco_hydro_13. Pfam:PF00128; Alpha-amylase;1.; High confidence in function and specificity; putative alpha-D-1,4-glucosidase	complement(2538956..2540617)	Azoarcus sp. BH72	4607349
YP_933815.1	CDS	spr1	NC_008702.1	2540718	2541824	D	Glucan 13-beta-glucosidase precursor (EC 3.2.1.58) (Exo-13-beta- glucanase).BETA-GLUCANASES PARTICIPATE IN THE METABOLISM OF BETA-GLUCAN THE MAIN STRUCTURAL COMPONENT OF THE CELL WALL. IT COULD ALSO FUNCTION BIOSYNTHETICALLY AS A TRANSGLYCOSYLASE. 33% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1.; High confidence in function and specificity; putative glucan 1,3-beta-glucosidase	2540718..2541824	Azoarcus sp. BH72	4609492
YP_933816.1	CDS	azo2312	NC_008702.1	2541810	2543588	R	Conserved hypothetical membrane protein. Homology to Avin02002177 of Azotobacter vinelandii of 61% (gi|53611929|ref|ZP_00090985.2|(NBCI ENTREZ)). InterPro: ABC transporter (IPR003439). Pfam: ABC transporter. no signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2541810..2543588)	Azoarcus sp. BH72	4609890
YP_933817.1	CDS	glk2	NC_008702.1	2543591	2544544	R	Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 24% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1.; High confidence in function and specificity; putative glucokinase	complement(2543591..2544544)	Azoarcus sp. BH72	4607350
YP_933818.1	CDS	azo2314	NC_008702.1	2544700	2546202	D	Family membership; glycosyltransferase	2544700..2546202	Azoarcus sp. BH72	4608890
YP_933819.1	CDS	azo2315	NC_008702.1	2546172	2546876	D	Conserved hypothetical tyrosine/serine phosphatase,; Conserved hypothetical protein; putative tyrosine/serine phosphatase	2546172..2546876	Azoarcus sp. BH72	4607351
YP_933820.1	CDS	msbA1	NC_008702.1	2546873	2548639	D	Lipid A export ATP-binding/permease msbA. MsbA (TC 3.A.1.106.1) is involved in lipid A and possibly also glycerophospholipids export. The transmembrane domain (TMD) forms a pore in the inner membrane and the ATP-binding domain (NBD) is responible for energy generation. Similar to TREMBL:Q8ZGA9; TREMBL:Q8XXB6; SWISSPROT:P60752 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR001140): ABC transporter transmembrane region. Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting five transmembrane helices. TC (3.A.1.106): The Lipid Exporter (LipidE) Family.; High confidence in function and specificity; Lipid A export ATP-binding/permease	2546873..2548639	Azoarcus sp. BH72	4607352
YP_933821.1	CDS	azo2317	NC_008702.1	2548636	2549829	D	Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein to the data bank. no dmains predicted. no signal peptide. no TMHs; hypothetical protein	2548636..2549829	Azoarcus sp. BH72	4609275
YP_933822.1	CDS	azo2318	NC_008702.1	2549826	2551112	D	Hypothetical membrane protein. homology to rsc2204 of R.solanacearum of 28% (trembl|Q8XXB2(SRS)). no domains predicted. no signal peptide. 10 TMHs; hypothetical protein	2549826..2551112	Azoarcus sp. BH72	4607353
YP_933823.1	CDS	azo2319	NC_008702.1	2551109	2551732	D	CMP-N-acetylneuraminate-beta-galactosamide-alpha- 23- sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-23-sialyltransferase) (Alpha 23-ST) (Gal-NAc6S) (Gal-beta-13-GalNAc-alpha-23-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I). IT MAY BE RESPONSIBLE FOR THE SYNTHESIS OF THE SEQUENCE NEUAC-ALPHA-23-GAL-BETA-13-GALNAC- FOUND ON SUGAR CHAINS O-LINKED TO THR OR SER AND ALSO AS A TERMINAL SEQUENCE ON CERTAIN GANGLIOSIDES. SIAT4-A AND SIAT4-B SIALYLATE THE SAME ACCEPTOR SUBSTRATES BUT EXHIBIT DIFFERENT KM VALUES.; Specificity unclear; glycosyltransferase	2551109..2551732	Azoarcus sp. BH72	4607354
YP_933824.1	CDS	azo2320	NC_008702.1	2551737	2552735	D	Conserved hypothetical protein. Homology to Rsph03001342 of Rhodobacter sphaeroides of 39% (gi|22957735|ref|ZP_00005426.1|(NBCI ENTREZ)). Has PF04230, Polysaccharide pyruvyl transferase;IPR007345 PS_pyruv_trans; Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora. No signal peptide. No TMHs; hypothetical protein	2551737..2552735	Azoarcus sp. BH72	4607355
YP_933825.1	CDS	waaC1	NC_008702.1	2552955	2554031	D	High confidence in function and specificity; lipopolysaccharide heptosyltransferase I	2552955..2554031	Azoarcus sp. BH72	4607356
YP_933826.1	CDS	azo2322	NC_008702.1	2554028	2555143	D	Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	2554028..2555143	Azoarcus sp. BH72	4610101
YP_933827.1	CDS	azo2323	NC_008702.1	2555172	2556242	D	Lipopolysaccharide core biosynthesis glycosyl transferase lpsE (EC 2.-.-.-).; Specificity unclear; glycosyltransferase	2555172..2556242	Azoarcus sp. BH72	4607357
YP_933828.1	CDS	azo2324	NC_008702.1	2556244	2557083	D	29% Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1.; High confidence in function and specificity; putative polysaccharide deacetylase	2556244..2557083	Azoarcus sp. BH72	4607358
YP_933829.1	CDS	azo2325	NC_008702.1	2557095	2557580	D	Conserved hypothetical protein. Homology to CV1439 of Chromobacterium violaceum of 58% (trembl:Q7NY36). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2557095..2557580	Azoarcus sp. BH72	4607359
YP_933830.1	CDS	azo2326	NC_008702.1	2557664	2559307	D	Conserved hypothetical signaling protein,; Conserved hypothetical protein; putative signaling protein	2557664..2559307	Azoarcus sp. BH72	4607360
YP_933831.1	CDS	cbl	NC_008702.1	2559320	2560276	R	HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity; transcriptional regulator CysB-like protein	complement(2559320..2560276)	Azoarcus sp. BH72	4607361
YP_933832.1	CDS	pspF	NC_008702.1	2560607	2561695	D	Probable transcriptional regulator,; Specificity unclear; transcriptional regulator	2560607..2561695	Azoarcus sp. BH72	4608437
YP_933833.1	CDS	tonB2	NC_008702.1	2561964	2562611	D	For the transport of bound iron across the inner membrane, a receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer membrane receptors. InterPro: Proline-rich region; Function unclear; periplasmic biopolymer transport protein linking inner and outer membranes	2561964..2562611	Azoarcus sp. BH72	4609639
YP_933834.1	CDS	exbB4	NC_008702.1	2562648	2563469	D	Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 36%. ExbB is part of the TonB-dependent transduction complex. The tonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family signal peptide most probable 4TMHs; Family membership; putative biopolymer transport protein ExbB	2562648..2563469	Azoarcus sp. BH72	4609963
YP_933835.1	CDS	exbD5	NC_008702.1	2563476	2563895	D	Putative biopolymer transport protein exbD. Homology to exbD of E. coli of 34%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership; putative biopolymer transport protein ExbD	2563476..2563895	Azoarcus sp. BH72	4608699
YP_933836.1	CDS	exbD6	NC_008702.1	2563914	2564342	D	Putative biopolymer transport protein. Homology to exbD1 of X. campestris of 31%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership; putative biopolymer transport protein ExbD	2563914..2564342	Azoarcus sp. BH72	4608704
YP_933837.1	CDS	azo2333	NC_008702.1	2564464	2565738	D	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7WF48 (49% identity); TREMBL:Q881X8 (49% identity). Pfam (PF00529): HlyD family secretion protein. TMHMM reporting one transmembrane helix. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership; membrane fusion protein	2564464..2565738	Azoarcus sp. BH72	4608705
YP_933838.1	CDS	azo2334	NC_008702.1	2565735	2568839	D	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer,SWISSPROT:P76399 (44% identity). Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM reporting 10 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; High confidence in function and specificity; RND efflux transporter permease	2565735..2568839	Azoarcus sp. BH72	4607362
YP_933839.1	CDS	azo2335	NC_008702.1	2568839	2571973	D	AcrB/AcrD/AcrF family member. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q881X7 (44% identity); SWISSPROT:P76399 (48% identity). InterPro (IPR001036): Acriflavin resistance protein Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM reporting 10 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. HTH reporting nucleic acid binding motif.; Specificity unclear; RND efflux transporter permease	2568839..2571973	Azoarcus sp. BH72	4607363
YP_933840.1	CDS	opcM1	NC_008702.1	2572063	2573526	D	Putative outer membrane efflux protein. Homology to opcM of B. cepacia of 36%. Component of an efflux system that confers multiple antibiotic resistence. Pfam: outer membrane efflux protein signal peptide no TMHs; Family membership; putative outer membrane efflux protein	2572063..2573526	Azoarcus sp. BH72	4607364
YP_933841.1	CDS	azo2337	NC_008702.1	2573541	2574254	D	Conserved hypothetical hydrogenase cytochrone b-type subunit. Homology to C. vinosum of 48% (trembl|Q46471). Involved in electron transfer from hydrogen to oxygen. Pfam: Nickel-dependent hydrogenase b-type cytochrome. probable signal peptide. probable 4 TMHs; Family membership; hydrogenase cytochrome b-type subunit	2573541..2574254	Azoarcus sp. BH72	4609451
YP_933842.1	CDS	prc	NC_008702.1	2574305	2576401	D	Tail-specific protease precursor (EC 3.4.21.102) (Protease Re) (PRC protein) (C-terminal processing peptidase). prc: carboxyl-terminal protease; High confidence in function and specificity; tail-specific penicillin-binding protein protease	2574305..2576401	Azoarcus sp. BH72	4607365
YP_933843.1	CDS	cycA2	NC_008702.1	2577133	2577597	R	Probable cytochrome c'. Homology to cycA of C. vinosum of 48% (sprot|CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN. InterPro: Cytochrome c class II (IPR002321) Pfam: Cytochrome c singal peptide no TMHs; Function unclear; cytochrome c'	complement(2577133..2577597)	Azoarcus sp. BH72	4609622
YP_933844.1	CDS	azo2340	NC_008702.1	2577644	2578648	R	Dienelactone hydrolases play a crucial role in chlorocatechol degradation via the modified ortho cleavage pathway, TREMBL:Q8XBV0 (48% identity); TREMBL:Q8EI44 (45% identity). InterPro (IPR002925): Dienelactone hydrolase. InterPro (IPR000379): Esterase/lipase/thioesterase. Pfam (PF01738): Dienelactone hydrolase family. SignalP predicting signal peptide.; Family membership; dienelactone hydrolase family protein	complement(2577644..2578648)	Azoarcus sp. BH72	4608549
YP_933845.1	CDS	gnl	NC_008702.1	2578692	2579669	R	Gluconolactonase precursor (D-glucono-delta-lactone lactonohydrolase).HYDROLYZES THE GLUCONOLACTONE FORMED BY GLUCOSE-FRUCTOSE OXIDOREDUCTASE AND THAT FORMED IN AEROBIC CONDITIONS BY THE GLUCOSE DEHYDROGENASE PRESENT. 30% SMP-30. Pfam:PF03758; SMP-30; 1. Signal peptide: present.; High confidence in function and specificity; putative gluconolactonase	complement(2578692..2579669)	Azoarcus sp. BH72	4607366
YP_933846.1	CDS	cc41	NC_008702.1	2579886	2580566	R	Putative cytochrome c4. Homology to cc4 of A. vinelandii of 34% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs; Family membership; putative cytochrome c4	complement(2579886..2580566)	Azoarcus sp. BH72	4608929
YP_933847.1	CDS	bcp3	NC_008702.1	2580648	2581226	R	Conserved hypothetical bacterioferritin comigratory protein homolog. Homology to bp1307 of B. pertussis of 43% (trembl|Q7VYL2). Pfam: AhpC/TSA family. signal peptide. no TMHs; Family membership; bacterioferritin comigratory protein	complement(2580648..2581226)	Azoarcus sp. BH72	4608438
YP_933848.1	CDS	azo2344	NC_008702.1	2581238	2581618	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(2581238..2581618)	Azoarcus sp. BH72	4608381
YP_933849.1	CDS	azo2345	NC_008702.1	2581721	2583178	R	Conserved hypothetical secreted protein. Homology to RB5328 of Rhodopirellula baltica of 47% (trembl|Q7US09(SRS)). Signal Peptide present. No TMH reported Present. Has PF07394, Protein of unknown function (DUF1501);IPR010869;This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.; Conserved hypothetical protein; hypothetical protein	complement(2581721..2583178)	Azoarcus sp. BH72	4607367
YP_933850.1	CDS	azo2346	NC_008702.1	2583205	2585517	R	Conserved hypothetical secreted protein. Homology to RB6288 of Rhodopirellula baltica of 30% (trembl|Q7UQJ4(SRS)). No domains predicted. No TMHs. Signal P reporting signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(2583205..2585517)	Azoarcus sp. BH72	4607368
YP_933851.1	CDS	fyuA	NC_008702.1	2586159	2588936	D	Yersinia enterocolitica,iron-repressible outer membrane protein, FyuA. FyuA:RECEPTOR FOR THE BACTERIOCIN PESTICIN AND FOR THE SIDEROPHORE YERSINIABACTIN. TonB-dependent outer membrane receptor.; Function unclear; putative TonB-dependent receptor	2586159..2588936	Azoarcus sp. BH72	4607369
YP_933852.1	CDS	azo2348	NC_008702.1	2588979	2589458	R	Similar to a Rhodanese-related sulfurtransferase,PspE. , PspE:Thiosulphate sulphurtransferase ( 2.8.1.1) is an enzyme which catalyzes the transfer of the sulphane atom of thiosulphate to cyanide, to form sulphite and thiocyanate.Involved in cyanide detoxification., Signal peptide present.,; Function unclear; putative rhodanese sulfurtransferase	complement(2588979..2589458)	Azoarcus sp. BH72	4608850
YP_933853.1	CDS	azo2349	NC_008702.1	2589804	2591366	D	Conserved hypothetical membrane protein. Homology to PA0435 of Pseudomonas aeruginosa of 35% (trembl|Q9I682(SRS)). No domains predicted. Signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	2589804..2591366	Azoarcus sp. BH72	4607370
YP_933854.1	CDS	azo2350	NC_008702.1	2591415	2591855	R	Conserved hypothetical protein. Homology to orf of Desulfovibrio vulgaris of 41% (tremblnew|AAS97780(SRS)). No domain predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2591415..2591855)	Azoarcus sp. BH72	4607371
YP_933855.1	CDS	arsC1	NC_008702.1	2592005	2592502	D	Putative arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier),; Family membership; putative arsenate reductase (glutaredoxin)	2592005..2592502	Azoarcus sp. BH72	4607372
YP_933856.1	CDS	arsR	NC_008702.1	2592559	2592918	D	Putative regulatory protein arsR-family arsenical resistance operon repressor, smtB from Synechococcus PCC 7942, which acts as a transcriptional repressor of the smtA gene that codes for a metallothionein; cadC, a protein required for cadmium-resistance; and hypothetical protein yqcJ from Bacillus subtilis.; Family membership; ArsR family regulatory protein	2592559..2592918	Azoarcus sp. BH72	4608352
YP_933857.1	CDS	arsC2	NC_008702.1	2592915	2593328	D	Putative arsenate reductase,; Family membership; putative arsenate reductase (glutaredoxin)	2592915..2593328	Azoarcus sp. BH72	4608355
YP_933858.1	CDS	arsB	NC_008702.1	2593338	2594402	D	Putative arsenical-resistance protein arsB,; Family membership; putative arsenical-resistance protein	2593338..2594402	Azoarcus sp. BH72	4608353
YP_933859.1	CDS	arsD	NC_008702.1	2594417	2594788	D	Arsenical resistance operon trans-acting repressor ArsD,; Family membership; arsenical resistance operon trans-acting repressor	2594417..2594788	Azoarcus sp. BH72	4608351
YP_933860.1	CDS	arsA	NC_008702.1	2594802	2596550	D	Arsenite-transporting ATPase,; High confidence in function and specificity; arsenite-transporting ATPase	2594802..2596550	Azoarcus sp. BH72	4608354
YP_933861.1	CDS	azo2357	NC_008702.1	2596593	2598086	R	Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.-) (Glu-ADT subunit A). Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).; Family membership; amidase	complement(2596593..2598086)	Azoarcus sp. BH72	4608350
YP_933862.1	CDS	azo2358	NC_008702.1	2598201	2599088	R	Hypothetical AraC-family transcriptional regulator; AraC family transcriptional regulator	complement(2598201..2599088)	Azoarcus sp. BH72	4607373
YP_933863.1	CDS	azo2359	NC_008702.1	2599193	2599573	R	oxaloacetate tautomerase,41% identity to TrEMBL;O32183;YusQ protein [yusQ] [Bacillus subtilis subsp. subtilis str. 168]. Has PF01361;(IPR004370);Tautomerase enzyme;This family includes the enzyme 4-oxalocrotonate tautomerase Q01468 that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate. No Signal peptide or TMH reported present.; Conserved hypothetical protein; oxaloacetate tautomerase	complement(2599193..2599573)	Azoarcus sp. BH72	4607374
YP_933864.1	CDS	azo2360	NC_008702.1	2599708	2600517	D	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	2599708..2600517	Azoarcus sp. BH72	4607375
YP_933865.1	CDS	azo2361	NC_008702.1	2600495	2601667	R	Acetyl esterase:-has an esterase activity. triacetyl glycerol (triacetin) is a substrate of the enzyme. Entry name SWISSPROT:AES_ECOLI Prim. accession # P23872 Identities = 57/229 (24%) InterPro IPR002168; Lipolytic_enzyme. IPR000379; Ser_estrs. Pfam :-Thioesterase Prediction: Non-secretory protein Signal peptide probability: 0.233 Number of predicted TMHs: 0; Family membership; putative acetyl esterase	complement(2600495..2601667)	Azoarcus sp. BH72	4607376
YP_933866.1	CDS	azo2362	NC_008702.1	2601814	2603754	R	Putative sensor kinase/response regulator hybrid protein,; Specificity unclear; putative sensor kinase/response regulator hybrid protein	complement(2601814..2603754)	Azoarcus sp. BH72	4607377
YP_933867.1	CDS	sbp2	NC_008702.1	2604007	2605017	R	Sulfate-binding protein precursor, Sbp. 69% Sulphate_bind. IPR005669; Thiosulph_bind.InterPro: Prokaryotic sulfate-/thiosulfate-binding protein. TIGRFAMs:TIGR00971; 3a0106s03; 1. Belongs to the prokaryotic sulfate binding protein family. In other bacteria Sbp is a periplasmic component of an ABC transport system.; High confidence in function and specificity; putative periplasmic sulfate-binding protein	complement(2604007..2605017)	Azoarcus sp. BH72	4607378
YP_933868.1	CDS	azo2364	NC_008702.1	2605073	2605756	R	Conserved hypothetical secreted protein. Homology to bll5801 of B. japonicum of 57% (trembl|Q89I38(SRS)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(2605073..2605756)	Azoarcus sp. BH72	4609842
YP_933869.1	CDS	groES2	NC_008702.1	2606215	2606502	D	Chaperonin GroES. Homology to groES of B. japonicum of 58% (sprot|CH11_BRAJA). Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. InterPro: Chaperonins cpn10 (10 Kd subunit)(IPR001476) Pfam: chaperonin 10 Kd subunit no signal peptide no TMH; High confidence in function and specificity; chaperonin GroES	2606215..2606502	Azoarcus sp. BH72	4607379
YP_933870.1	CDS	groEL3	NC_008702.1	2606556	2608199	D	Chaperonin GroEL. Homology to groEL of B. japonicum of 65% (SWISSPROT:CH61_BRAJA). Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity). Pfam: TCP-1/cpn60 chaperonin family no TMHs; High confidence in function and specificity; chaperonin GroEL	2606556..2608199	Azoarcus sp. BH72	4608941
YP_933871.1	CDS	azo2367	NC_008702.1	2608274	2609170	R	Transcriptional regulator, LysR family,; Function unclear; LysR family transcriptional regulator	complement(2608274..2609170)	Azoarcus sp. BH72	4608939
YP_933872.1	CDS	azo2368	NC_008702.1	2609291	2610286	D	Conserved hypothetical protein. Homology to RSc3335 of Ralstonia solanacearum of 52% (gnl|keqq|rso:RS02569(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2609291..2610286	Azoarcus sp. BH72	4607380
YP_933873.1	CDS	azo2369	NC_008702.1	2610283	2610723	D	Conserved hypothetical membrane protein. Homology to Pflu02000368 of Pseudomonas fluorescens of 34% (gi|48732319|ref|ZP_00266062.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	2610283..2610723	Azoarcus sp. BH72	4607381
YP_933874.1	CDS	azo2370	NC_008702.1	2610763	2611167	D	Hypothetical secreted protein. No domains predicted. No TMHs. Signal Peptide present. Weak homology with hits in the database.; hypothetical protein	2610763..2611167	Azoarcus sp. BH72	4607382
YP_933875.1	CDS	azo2371	NC_008702.1	2611545	2611892	R	30S ribosomal protein S4, truncated. Homology of aa 1 to 108 with rpsD of N. europaea of 67% (sprot|RS4B_NITEU(SRS)). With S5 and S12 plays an important role in translational accuracy (By similarity). Pfam: Ribosomal protein S4/S9 n-terminal domain. no signal peptide. no TMHs; Family membership; partiell 30S ribosomal protein S4, truncated	complement(2611545..2611892)	Azoarcus sp. BH72	4607383
YP_933876.1	CDS	azo2372	NC_008702.1	2611911	2612165	R	Hypothetical secreted protein. No homology with the data bank. No domains predicted. Signal peptide present. No TMHs; hypothetical protein	complement(2611911..2612165)	Azoarcus sp. BH72	4607384
YP_933877.1	CDS	fecI	NC_008702.1	2612445	2612945	D	FecI: belongs to the extracytoplasmic-function (ECF) sigma factor, which represent a subgroup of the sigma 70 family. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Involved in iron metabolism.; High confidence in function and specificity; RNA polymerase ECF-subfamily sigma-70 factor	2612445..2612945	Azoarcus sp. BH72	4607385
YP_933878.1	CDS	fecR	NC_008702.1	2612948	2613934	D	FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. Involved in iron metabolism.; High confidence in function and specificity; putative transmembrane sensor	2612948..2613934	Azoarcus sp. BH72	4608754
YP_933879.1	CDS	fecA	NC_008702.1	2614041	2616434	D	Ferric-citrate outer membrane receptor,FecA.Involved in the recognition and internalization of ferric-citrate in E.coli. SPECIFIC RECEPTOR FOR THE SIDEROPHORE FERRIC PSEUDOBACTIN 358. InterPro: TonB-dependent receptor protein; High confidence in function and specificity; putative ferric-citrate TonB-dependent receptor	2614041..2616434	Azoarcus sp. BH72	4608755
YP_933880.1	CDS	azo2376	NC_008702.1	2616506	2617735	D	Conserved hypothetical membrane protein. Homology to NE0537 of Nitrosomonas europaea of 40% (trembl|Q82WX0(SRS)). no domains predicted. signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	2616506..2617735	Azoarcus sp. BH72	4608753
YP_933881.1	CDS	azo2377	NC_008702.1	2618005	2618457	R	Similar to Rhodanese, a sulphurtransferase involved in cyanide detoxification. Non-secretory protein. Probable Hypothetical protein RP600.; Function unclear; hypothetical protein	complement(2618005..2618457)	Azoarcus sp. BH72	4607386
YP_933882.1	CDS	azo2378	NC_008702.1	2618632	2619291	D	Hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q87X35 Has PF04336, Protein of unknown function,DUF479;IPR007431,This family includes several bacterial proteins of uncharacterised function.; Function unclear; hypothetical protein	2618632..2619291	Azoarcus sp. BH72	4607387
YP_933883.1	CDS	azo2379	NC_008702.1	2619273	2620175	R	Hypothetical protein, 44% identity (54% similarity) to TrEMBL;Q82TM9. Has PF01636;Phosphotransferase enzyme family;IPR002575,APH_trans;This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:-aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. Has PF03881,Fructosamine kinase;This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterised but probably have a similar or identical function.; Specificity unclear; hypothetical protein	complement(2619273..2620175)	Azoarcus sp. BH72	4607388
YP_933884.1	CDS	azo2380	NC_008702.1	2620360	2621466	D	Glycosyltransferase; Specificity unclear; glycosyltransferase	2620360..2621466	Azoarcus sp. BH72	4607389
YP_933885.1	CDS	azo2381	NC_008702.1	2621450	2622997	D	Conserved hypothetical protein. Extremely weak homology with hits in the Database spanning the entire length of protein. Has PF02366, Dolichyl-phosphate-mannose-protein mannosyltransferase; IPR003342,Glyco_trans_39:This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferases. These proteins are responsible for O-linked glycosylation of proteins, they catalyse the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Q94891 Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to STT3. TMHMM2 reporting 2 TMH's present. Signal peptide not present.; Function unclear; dolichyl-phosphate-mannose-protein mannosyltransferase	2621450..2622997	Azoarcus sp. BH72	4607390
YP_933886.1	CDS	azo2382	NC_008702.1	2623216	2624124	D	Conserved hypothetical secreted protein. Homology to TdenA01002104 of Thiobacillus denitrificans of 56% (gi|52006510|ref|ZP_00333890.1|(NBCI ENTREZ)). No domains predicted. Signal P repoting a signal peptide present. NO TMH being present.; Conserved hypothetical protein; hypothetical protein	2623216..2624124	Azoarcus sp. BH72	4607391
YP_933887.1	CDS	azo2383	NC_008702.1	2624136	2624690	D	Conserved hypothetical protein. Homology to rsp0720 of R. solanacearum of 43% (trembl|Q8XRW1(SRS)). Pfam: FMN_binding domain. This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins. Siganl peptide. no TMHs; hypothetical protein	2624136..2624690	Azoarcus sp. BH72	4607392
YP_933888.1	CDS	azo2384	NC_008702.1	2624734	2625561	D	Conserved hypothetical ApbE family protein. Homology to so1090 of S. oneidensis of 43% (trembl|Q8EHX0). Pfam: ApbE family. This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. no signal. peptide no TMH; Family membership; ApbE family protein	2624734..2625561	Azoarcus sp. BH72	4607393
YP_933889.1	CDS	azo2385	NC_008702.1	2625563	2626036	D	Hypothetical membrane protein. No homology of the entire protein to the data bank. No domains predicted. signal peptide. 3 TMHs; hypothetical protein	2625563..2626036	Azoarcus sp. BH72	4607394
YP_933890.1	CDS	azo2386	NC_008702.1	2626263	2626706	D	Conserved hypothetical membrane protein. Homology to BB4221 of Bordetella bronchiseptica of 32% (trembl|Q7WFQ0). Has PF07331, Protein of unknown function (DUF1468);IPR009936;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	2626263..2626706	Azoarcus sp. BH72	4607395
YP_933891.1	CDS	azo2387	NC_008702.1	2626714	2628201	D	Conserved hypothetical membrane protein. Homology to an orf of R. palustris of 63% (tremblnew|CAE27761(SRS)). Has PF01970, Integral membrane protein DUF112;IPR002823:Members of this prokaryotic family have no known function. no signal peptide. 10 TMHs; Conserved hypothetical protein; hypothetical protein	2626714..2628201	Azoarcus sp. BH72	4607396
YP_933892.1	CDS	azo2388	NC_008702.1	2628235	2628873	D	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domain predicted. no signal peptide. 4 TMHs; hypothetical protein	2628235..2628873	Azoarcus sp. BH72	4607397
YP_933893.1	CDS	ssuF	NC_008702.1	2628910	2629125	R	Probable Molybdenum-pterin binding protein II. Organosulfonate utilization protein SsuF InterPro: Molybdenum-pterin binding domain TIGRFAM: Mop: molybdenum-pterin binding domain; High confidence in function and specificity; molybdenum-pterin-binding protein	complement(2628910..2629125)	Azoarcus sp. BH72	4607398
YP_933894.1	CDS	azo2390	NC_008702.1	2629358	2629729	R	Conserved hypothetical protein. Homology to Daro03001711 of Dechloromonas aromatica of 36% (gi|53730477|ref|ZP_00348804.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2629358..2629729)	Azoarcus sp. BH72	4609900
YP_933895.1	CDS	tauA	NC_008702.1	2630041	2631066	D	Part of the ABC transporter complex tauABC involved in taurine as a sulfur source import. Similar to the putative aliphatic sulfonates periplasmic-binding protein tauA in E.coli. Probably also involved in nitrate and bicarbonate transport.; Function unclear; putative sulfonate transport system periplasmic component	2630041..2631066	Azoarcus sp. BH72	4607399
YP_933896.1	CDS	tauB	NC_008702.1	2631101	2631892	D	Part of the ABC transporter complex tauABC involved in taurine import as a sulfur source.Probably responsible for energy coupling to the transport system.Similar to the aliphatic sulfonate transport membrane protein, tauB in E.coli. Probably also involved in nitrate and bicarbonate transport.; High confidence in function and specificity; putative sulfonate transport system ATP-binding protein	2631101..2631892	Azoarcus sp. BH72	4609921
YP_933897.1	CDS	tauC	NC_008702.1	2632087	2632899	D	Part of the ABC transporter complex tauABC involved in taurine import as sulfur source. Probably responsible for the translocation of the substrate across the membrane.Similar to the aliphatic sulfonate permease, tauC in E.coli. Probably also involved in nitrate and bicarbonate transport.; High confidence in function and specificity; putative sulfonate transport system permease	2632087..2632899	Azoarcus sp. BH72	4609922
YP_933898.1	CDS	azo2394	NC_008702.1	2632917	2633645	D	Hypothetical membrane protein. Homology to COG2143 from 114 aa to 228 aa. InterPro: Thioredoxin (IPR006662). no signal peptide. 1 TMH; hypothetical protein	2632917..2633645	Azoarcus sp. BH72	4609923
YP_933899.1	CDS	phaE	NC_008702.1	2633703	2635040	D	Phenylacetate-coenzyme A ligase (PA-CoA ligase).Coenzyme F390 synthase. CATALYZES THE ACTIVATION OF PHENYLACETIC ACID TO PHENYLACETYL-COA. InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity; phenylacetate--CoA ligase	2633703..2635040	Azoarcus sp. BH72	4607400
YP_933900.1	CDS	azo2396	NC_008702.1	2635527	2637713	D	Putative outer membrane TonB-dependent receptor protein. 43% TonB_receptor. Pfam:PF00593; TonB_dep_Rec; 1.; Function unclear; putative TonB-dependent receptor	2635527..2637713	Azoarcus sp. BH72	4609536
YP_933901.1	CDS	azo2397	NC_008702.1	2637720	2638544	R	Conserved hypothetical signaling protein,; Conserved hypothetical protein; putative signaling protein	complement(2637720..2638544)	Azoarcus sp. BH72	4607401
YP_933902.1	CDS	azo2398	NC_008702.1	2638757	2639365	D	Conserved hypothetical protein. Homology to rsc1344 of R. solanacearum of 42% (trembl|Q8XZQ1). no domains predicted. no signal peptide. no TMHs; hypothetical protein	2638757..2639365	Azoarcus sp. BH72	4607402
YP_933903.1	CDS	cysK	NC_008702.1	2639458	2640438	D	Cysteine synthase A,; High confidence in function and specificity; cysteine synthase A	2639458..2640438	Azoarcus sp. BH72	4607403
YP_933904.1	CDS	azo2400	NC_008702.1	2640828	2643044	D	Putative TonB outer membrane receptor protein.31% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present.; Function unclear; putative TonB-dependent receptor protein	2640828..2643044	Azoarcus sp. BH72	4608560
YP_933905.1	CDS	azo2401	NC_008702.1	2643054	2643623	D	Conserved hypothetical secreted protein. Homology to rsp0812 of R. solanacearum of 30% (trembl|Q8XRL9). no damians predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2643054..2643623	Azoarcus sp. BH72	4607404
YP_933906.1	CDS	barA	NC_008702.1	2643620	2646658	D	Putative sensor-regulator protein,; Specificity unclear; putative sensor-regulator protein	2643620..2646658	Azoarcus sp. BH72	4607405
YP_933907.1	CDS	wspR2	NC_008702.1	2646655	2647560	D	Probable two-component response regulator,; High confidence in function and specificity; two-component response regulator	2646655..2647560	Azoarcus sp. BH72	4608376
YP_933908.1	CDS	azo2404	NC_008702.1	2647703	2649856	D	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	2647703..2649856	Azoarcus sp. BH72	4610116
YP_933909.1	CDS	ohr	NC_008702.1	2649868	2650305	R	Probable organic hydroperoxide resistance protein. Homology to ohr of X. campestris of 50% (SWISSPROT:OHR_XANAC). Organic hydroperoxide detoxification protein. Confers increased resistance to tert-butyl hydroperoxide killing. InterPro: OsmC-like protein (IPR003718) Pfam: OsmC-like protein no signal peptide no TMH; High confidence in function and specificity; organic hydroperoxide resistance protein	complement(2649868..2650305)	Azoarcus sp. BH72	4607406
YP_933910.1	CDS	azo2406	NC_008702.1	2650430	2654014	R	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; 2-oxoacid ferredoxin oxidoreductase	complement(2650430..2654014)	Azoarcus sp. BH72	4609440
YP_933911.1	CDS	bkdR	NC_008702.1	2654233	2654715	D	Bkd operon transcriptional regulator, similarity to SWISSPROT: (38% Pseudomonas putida, bkd operon transcriptional regulator BdkR) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; bkd operon transcriptional regulator	2654233..2654715	Azoarcus sp. BH72	4607407
YP_933912.1	CDS	azo2408	NC_008702.1	2654882	2657899	D	Hypothetical sensor protein,; Conserved hypothetical protein; sensor protein	2654882..2657899	Azoarcus sp. BH72	4608397
YP_933913.1	CDS	azo2409	NC_008702.1	2657913	2659973	R	Conserved hypothetical sodium:solute sympoter. Homology to bb3915 of B. bronchiseptica of 57% (trembl|Q7WCM0). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. Tigrfam: sss: SSS sodium solute transporter superfamily. Pfam: Sodium:solute symporter family. signal peptide. 13 TMHS; Family membership; putative sodium:solute sympoter	complement(2657913..2659973)	Azoarcus sp. BH72	4607408
YP_933914.1	CDS	azo2410	NC_008702.1	2660014	2662218	R	DNA polymerase III epsilon chain-like protein (EC 2.7.7.7). DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THE EPSILON SUBUNIT CONTAIN THE EDITING FUNCTION AND IS A PROOFREADING 3-5 EXONUCLEASE (BY SIMILARITY). dnaq: DNA polymerase III epsilon sub; Family membership; DNA polymerase III subunit epsilon	complement(2660014..2662218)	Azoarcus sp. BH72	4607409
YP_933915.1	CDS	yycF	NC_008702.1	2662346	2662720	R	Transcriptional regulatory protein yycF. Member of the two-component regulatory system yycG/yycF involved in the regulation of the ftsAZ operon. Binds to the ftsAZ P1 promoter sequence. Similar to SWISSPROT: sprot|YYCF_BACSU (50% Bacillus subtilis, transcriptional regulatory protein YycF) / sprot|PHOP_BACSU (47% Bacillus subtilis, alkaline phosphatase synthesis transcriptional regulatory protein PhoP) InterPro: IPR001789 Response_reg. Pfam: PF00072 Response_reg.; Specificity unclear; transcriptional regulator	complement(2662346..2662720)	Azoarcus sp. BH72	4607410
YP_933916.1	CDS	azo2412	NC_008702.1	2662752	2665499	R	Sensor histidine kinase mtrB (EC 2.7.3.-). Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals (By similarity). TREMBLnew:AAS80811; TREMBL:Q8PEZ5, 42% identity, 59% similarity; Pfam: Histidine kinase _,Phosphoacceptor domain. TIGRFAM: sss: sodium solute transporter sup. TMHMM predicted transmembrane helices. sss: SSS sodium solute transporter sup; Specificity unclear; two-component system sensor protein	complement(2662752..2665499)	Azoarcus sp. BH72	4610200
YP_933917.1	CDS	azo2413	NC_008702.1	2665499	2665696	R	Conserved hypothetical membrane protein. Homolgy to ttc0464 of T. thermophilus of 46% (tremble:Q72K63). no domains predicted. singal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2665499..2665696)	Azoarcus sp. BH72	4607411
YP_933918.1	CDS	acsB	NC_008702.1	2665962	2667926	R	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase	complement(2665962..2667926)	Azoarcus sp. BH72	4607412
YP_933919.1	CDS	fumB	NC_008702.1	2668208	2669899	D	Putative fumarate hydratase. Homology to fumB of E. coli of 25% (sprot|FUMB_ECOLI). It functions in the generation of fumarate for use as an anaerobic electron acceptor. Tigrfam: ttdA_fumA_fumB: hydro-lyases Fe-S type,tartrate/fumarate subfamily, alpha region; ttdB_fumA_fumB: hydro-lyases Fe-S type, tartrate/fumarate subfamily, beta region no signal peptide no TMHs; Family membership; putative fumarate hydratase	2668208..2669899	Azoarcus sp. BH72	4608275
YP_933920.1	CDS	azo2416	NC_008702.1	2669865	2670155	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2669865..2670155)	Azoarcus sp. BH72	4608845
YP_933921.1	CDS	nnrS	NC_008702.1	2670306	2671496	R	NnrS is a putative heme-Cu protein and a member of the short-chain dehydrogenase family, probably involved in the nitric oxide metabolism. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase. 40% NnrS. TMhelix:10 Pfam:PF05940; NnrS; 1.; Function unclear; putative heme-Cu-containing membrane protein	complement(2670306..2671496)	Azoarcus sp. BH72	4607413
YP_933922.1	CDS	gapB	NC_008702.1	2671716	2672762	D	D-erythrose 4-phosphate dehydrogenase(E4PDH), GapB protein. Could play a role in pyridoxal 5-phosphate synthesis.Involved in the reaction: d-erythrose 4-phosphate + nad(+) = 4-phosphoerythronate + nadh. 51% E4PD_g-proteo.IPR000173; GAP_dhdrogenase. Pfam:PF00044; gpdh; 1.PF02800; gpdh_C; 1. TIGR00274: glucokinase regulator-relate. TIGRFAMs:TIGR01532; E4PD_g-proteo; 1.; High confidence in function and specificity; putative D-erythrose 4-phosphate dehydrogenase	2671716..2672762	Azoarcus sp. BH72	4609387
YP_933923.1	CDS	nahR1	NC_008702.1	2672763	2673671	R	LysR-type transcriptional regulator NahR. Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes. Belongs to the LysR family of transcriptional regulators. Similar to SWISSPROT: sprot|NAHR_PSEPU (40% Pseudomonas putida, hth-type transcriptional activator NahR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Specificity unclear; putative LysR-type transcriptional regulator NahR	complement(2672763..2673671)	Azoarcus sp. BH72	4608859
YP_933924.1	CDS	nagI	NC_008702.1	2673841	2674878	D	Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagI is a gentisate 1,2-dioxygenase which converts gentisate to maleylpyruvate. Similar to TREMBL:O86041 (66% identity); TREMBL:Q8X655 (30% identity); TREMBL:Q8Y0F7 (33% identity).; High confidence in function and specificity; gentisate 1,2-dioxygenase	2673841..2674878	Azoarcus sp. BH72	4609324
YP_933925.1	CDS	nagK	NC_008702.1	2674933	2675643	D	Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagK is a fumarylpyruvate hydrolase which hydrolyzes fumarylpyruvate to fumarate and pyruvate. Similar to TREMBL:O86042 (67% identity); TREMBL:O07877 (63% identity); TREMBL:Q8G387 (50% identity). Pfam (PF01557): Fumarylacetoacetate (FAA) hydrolase family.; High confidence in function and specificity; fumarylpyruvate hydrolase	2674933..2675643	Azoarcus sp. BH72	4609311
YP_933926.1	CDS	nahG	NC_008702.1	2675686	2676879	D	catalyzes the formation of catechol from salicylate; salicylate hydroxylase	2675686..2676879	Azoarcus sp. BH72	4609312
YP_933927.1	CDS	nagL1	NC_008702.1	2676985	2677626	D	maleylpyruvate isomerase. Homology to nogL of Ralstonia sp U of 73% (AAD12621) NagL is a reduced glutathione-dependent maleylpyruvate isomerase catalyzing the isomerization of maleylpyruvate to fumarylpyruvate. InterPro: Glutathione S-transferase N terminus (IPR004045) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; High confidence in function and specificity; maleylpyruvate isomerase	2676985..2677626	Azoarcus sp. BH72	4609317
YP_933928.1	CDS	dctP3	NC_008702.1	2677699	2678685	D	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear; putative C4-dicarboxylate-binding periplasmic protein	2677699..2678685	Azoarcus sp. BH72	4609313
YP_933929.1	CDS	dctQ4	NC_008702.1	2679037	2679540	D	TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctM.IPR007387; DctQ.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF04290; DctQ; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1.; Specificity unclear; putative TRAP-type C4-dicarboxylate transport system small permease	2679037..2679540	Azoarcus sp. BH72	4608604
YP_933930.1	CDS	dctM4	NC_008702.1	2679537	2680814	D	Similar to a putative large integral C4-dicarboxylate membrane transport protein from W. succinogenes.DctM: TRAP dicarboxylate transporter. TREMBL:Q9ZEJ2 InterPro:IPR010656; DctM.IPR000252; DedA.IPR000524; HTH_GntR.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMHelix: 12. Signal peptide:present.; Specificity unclear; putative TRAP-type C4-dicarboxylate transport system large permease	2679537..2680814	Azoarcus sp. BH72	4608611
YP_933931.1	CDS	azo2427	NC_008702.1	2680831	2681421	R	Conserved hypothetical membrane protein. Homology to BB1720 of Bordetella bronchiseptica of 32% (trembl|Q7WLM5). Has PF03992, Antibiotic biosynthesis monooxygenase;IPR007138;This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 (Q9X9W3) is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue. TMHMM2 reporting 2 TMH's Present. No Signal Peptide present.; Conserved hypothetical protein; hypothetical protein	complement(2680831..2681421)	Azoarcus sp. BH72	4608600
YP_933932.1	CDS	azo2428	NC_008702.1	2681551	2682474	R	Conserved hypothetical secreted protein. Homology to an orf of T. aromatica of 48% (trembl|Q7B0A2). no domains. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(2681551..2682474)	Azoarcus sp. BH72	4607414
YP_933933.1	CDS	nahJ	NC_008702.1	2682655	2682846	R	4-oxalocrotonate tautomerase (EC 5.3.2.-) (4-OT). Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate. SPROT:Q9RHM8: 80% identity; 88% similarity InterPro: 4-oxalocrotonate tautomerase InterPro:IPR004370; Taut. ProDom: PD404143; Taut Pfam; PF01361; Tautomerase; 1. taut: 4-oxalocrotonate tautomerase helixturnhelix: reporting nucleic acid binding motif No transmembrane helices; High confidence in function and specificity; 4-oxalocrotonate tautomerase	complement(2682655..2682846)	Azoarcus sp. BH72	4607415
YP_933934.1	CDS	nahK	NC_008702.1	2683055	2683843	R	Similar to TREMBL:Q93JW1 (67% identity); TREMBL:Q9RHN0 (67% identity); SWISSPROT:P49155 (59% identity). Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity; 4-oxalocrotonate decarboxylase	complement(2683055..2683843)	Azoarcus sp. BH72	4609319
YP_933935.1	CDS	nahM	NC_008702.1	2683840	2684880	R	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase	complement(2683840..2684880)	Azoarcus sp. BH72	4609320
YP_933936.1	CDS	nahO	NC_008702.1	2684895	2685815	R	catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase	complement(2684895..2685815)	Azoarcus sp. BH72	4609322
YP_933937.1	CDS	azo2433	NC_008702.1	2685848	2686642	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8XUP8 (61% identity); TREMBL:Q9I400 (57% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR) superfamily. InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	complement(2685848..2686642)	Azoarcus sp. BH72	4609323
YP_933938.1	CDS	nahL	NC_008702.1	2686737	2687519	R	Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate. Meta-cleavage pathway for the degradation of phenols, cresols and catechol. Belongs to the todj/xyli/xylj/hpcg family. Similar to TREMBL:Q93JW5 (75% identity); TREMBL:Q9ZI58 (65% identity); SWISSPROT:P23107 (73% identity). InterPro (IPR002607): Hydratase/decarboxylase Pfam (PF01689): Hydratase/decarboxylase.; High confidence in function and specificity; 2-oxopent-4-enoate hydratase	complement(2686737..2687519)	Azoarcus sp. BH72	4607416
YP_933939.1	CDS	nahI	NC_008702.1	2687635	2689089	R	2-hydroxymuconic semialdehyde dehydrogenase (HMSD). Homology to nahI of P. stutzeri of 73% (TREMBL:Q9S602) 2-HYDROXYMUCONIC ACID SEMIALDEHYDE CAN BE CONVERTED TO 2-HYDROXYPENT-24-DIENOATE EITHER DIRECTLY BY THE ACTION OF 2-HYDROXYMUCONIC SEMIALDEHYDE HYDROLASE (HMSH) OR BY THE ACTION OF THREE SEQUENTIAL ENZYMES THE FIRST OF WHICH IS HMSD. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs proA: gamma-glutamyl phosphate reductas; 2-hydroxymuconic semialdehyde dehydrogenase	complement(2687635..2689089)	Azoarcus sp. BH72	4609321
YP_933940.1	CDS	azo2436	NC_008702.1	2689143	2689580	R	Conserved hypothetical protein. Homology to orf4 of P. putida of 59% (trembl|Q93JW8). Pfam: DUF336. This family contains uncharacterised sequences, including several GlcG proteins. The alignment contains many conserved motifs that are suggestive of cofactor binding and enzymatic activity. no signal peptide. no TMHs; hypothetical protein	complement(2689143..2689580)	Azoarcus sp. BH72	4609318
YP_933941.1	CDS	aphS	NC_008702.1	2689738	2690457	D	Transcriptional regulator,; High confidence in function and specificity; transcriptional regulator	2689738..2690457	Azoarcus sp. BH72	4607417
YP_933942.1	CDS	lapB2	NC_008702.1	2690810	2691739	R	In Pseudomonas sp. strain KL28 the genes,designated as lap (for long-chain alkylphenols), encoding enzymes for the catabolic 3- and 4-alkylphenol degradation pathway. Catechol 2,3-dioxygenase LapB,; High confidence in function and specificity; catechol 2,3-dioxygenase	complement(2690810..2691739)	Azoarcus sp. BH72	4608327
YP_933943.1	CDS	poxF	NC_008702.1	2691869	2692924	R	Probable phenol hydroxylase (EC 1.14.13.7) (Phenol 2-monooxygenase P5 component). Probable electron transfer from NADPH via FAD and the 2Fe-2S center to the oxygenase activity site of the enzyme. InterPro: Oxidoreductase FAD and NAD(P)-binding domain hisT_truA: tRNA pseudouridine synthase A; Specificity unclear; phenol hydroxylase subunit P5	complement(2691869..2692924)	Azoarcus sp. BH72	4609110
YP_933944.1	CDS	poxE	NC_008702.1	2693134	2693493	R	Pseudomonas sp. phenol hydroxylase P4 protein (EC 1.14.13.7, (phenol 2-monooxygenase P4 component). CATABOLIZES PHENOL AND SOME OF ITS METHYLATED DERIVATIVES. P4 IS REQUIRED FOR GROWTH ON PHENOL AND FOR IN VITRO PHENOL HYDROXYLASE ACTIVITY.; High confidence in function and specificity; phenol hydroxylase subunit P4	complement(2693134..2693493)	Azoarcus sp. BH72	4609604
YP_933945.1	CDS	poxD	NC_008702.1	2693966	2695519	R	Probable phenol hydroxylase subunit,68% identity(84% similarity) to trEMBL:Q9RAF6,Phenol hydroxylase component [phyC] [Ralstonia sp. KN1]. TrEMBL;Q9ZNP4 Has PF02332:Methane/Phenol/Toluene Hydroxylase;IPR003430;Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase A. Methane hydroxylase A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyses the monohydroxylation of a variety of unactivated alkenes,alicyclic, aromatic and heterocyclic compounds. Also included in this family is toluene-4-monooxygenase system protein A (EC: 1.14.13.-), which hydroxylates toluene to form P-cresol. PF04945:IPR007029; YHS domain; This short presumed domain is about 50 amino acid residues long. It often contains two cysteines that may be functionally important. This domain is found in copper transporting ATPases, some phenol hydroxylases and in a set of uncharacterised membrane proteins including Q9CNI0. This domain is named after three of the most conserved amino acids it contains. The domain may be metal binding,possibly copper ions. This domain is duplicated in some copper transporting ATPases.; High confidence in function and specificity; phenol hydroxylase subunit P3	complement(2693966..2695519)	Azoarcus sp. BH72	4609603
YP_933946.1	CDS	poxC	NC_008702.1	2695548	2695817	R	Probable phenol hydrolase, subunit P2. Catabolizes phenol and some of its methylated derivatives. p2 is required for growth on phenol, and for in vitro phenol hydroxylase activity. Similar to SWISSPROT:P19731 (47% similarity,71% identity). Pfam (PF02406): MmoB/DmpM family.; High confidence in function and specificity; phenol hydrolase subunit P2	complement(2695548..2695817)	Azoarcus sp. BH72	4609602
YP_933947.1	CDS	poxB	NC_008702.1	2695828	2696823	R	Probable Phenol hydroxylase, subunit P1,65% identity(69% similarity) to TrEMBL;Q7WYF3 LapL [lapL] [Pseudomonas sp. KL28]. Has PF02332;Methane/Phenol/Toluene Hydroxylase domain;IPR003430: Bacterial phenol hydroxylase (EC: 1.14.13.7) is a multicomponent enzyme that catabolises phenol and some of its methylated derivatives. This family contains both the P1 and P3 polypeptides of phenol hydroxlase and the alpha and beta chain of methane hydroxylase A. Methane hydroxylase A (EC: 1.14.13.25) is responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyses the monohydroxylation of a variety of unactivated alkenes,alicyclic, aromatic and heterocyclic compounds. Also included in this family is toluene-4-monooxygenase system protein A (EC: 1.14.13.-), which hydroxylates toluene to form P-cresol. No signal peptide or TMH reported to be present.; Family membership; phenol hydroxylase subunit P1	complement(2695828..2696823)	Azoarcus sp. BH72	4609601
YP_933948.1	CDS	poxA	NC_008702.1	2696900	2697163	R	Putative phenol hydroxylase, subunit P0. Homology to poxA of R. eutropha of 34% (trembl:O84958) This family consists of several bacterial phenol hydroxylase subunit proteins which are part of a multicomponent phenol hydroxylase. Some bacteria can utilise phenol or some of its methylated derivatives as their sole source of carbon and energy. The first step in this process is the conversion of phenol into catechol. Catechol is then further metabolised via the meta-cleavage pathway into TCA cycle intermediates. Pfam: Phenol hydrolase subunit no signal peptide no TMHs; Family membership; putative phenol hydrolase subunit P0	complement(2696900..2697163)	Azoarcus sp. BH72	4609600
YP_933949.1	CDS	poxG	NC_008702.1	2697463	2697780	R	Probable ferredoxin-like protein. Homology to poxG of R. eutropha of 56% (trembl|O84964) The ferredoxins are iron-sulphur proteins that transfer electrons in a wide variety of metabolic reactions. Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership; ferredoxin-like protein	complement(2697463..2697780)	Azoarcus sp. BH72	4609599
YP_933950.1	CDS	poxR	NC_008702.1	2698080	2699780	D	Transcriptional regulatory protein probable involved into the phenol degradation pathway,; High confidence in function and specificity; positive regulator of phenol-degratives genes	2698080..2699780	Azoarcus sp. BH72	4609605
YP_933951.1	CDS	pobR1	NC_008702.1	2699777	2700655	R	pobR. Transcriptional regulator AraC family. InterPro: AraC type helix-turn-helix pdxH: pyridoxamine 5-phosphate oxidase; Function unclear; PobR regulator	complement(2699777..2700655)	Azoarcus sp. BH72	4609606
YP_933952.1	CDS	pobA	NC_008702.1	2700822	2702009	D	catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase	2700822..2702009	Azoarcus sp. BH72	4609594
YP_933953.1	CDS	azo2449	NC_008702.1	2702082	2703143	R	Putative two component response regulator,; Conserved hypothetical protein; putative two component response regulator	complement(2702082..2703143)	Azoarcus sp. BH72	4609593
YP_933954.1	CDS	azo2450	NC_008702.1	2703151	2705901	R	Putative two-component system sensor protein,; Function unclear; putative two-component system sensor protein	complement(2703151..2705901)	Azoarcus sp. BH72	4607418
YP_933955.1	CDS	azo2451	NC_008702.1	2706261	2706971	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q98J95 (48% identity); TREMBL:Q8YZV3 (43% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. PFAM (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	2706261..2706971	Azoarcus sp. BH72	4607419
YP_933956.1	CDS	azo2452	NC_008702.1	2707060	2707500	D	Conserved hypothetical protein, 31% identity (51% similarity) to TrEMBL;Q6NAA7. Has PF02637, GatB/Yqey domain;IPR003789:This domain is found in GatB and proteins related to bacterial Yqey P54464. It is about 140 amino acid residues long. This domain is found at the C terminus of GatB O30509 which transamidates Glu-tRNA to Gln-tRNA. The function of this domain is uncertain. It does however suggest that Yqey and its relatives have a role in tRNA metabolism. No Signal peptide or TMH present.; Function unclear; hypothetical protein	2707060..2707500	Azoarcus sp. BH72	4607420
YP_933957.1	CDS	azo2453	NC_008702.1	2707510	2708151	R	Probable negative transcriptional regulator,; Family membership; negative transcriptional regulator	complement(2707510..2708151)	Azoarcus sp. BH72	4607421
YP_933958.1	CDS	azo2454	NC_008702.1	2708500	2709174	D	Hypothetical secreted protein no homology of the entire protein to the data bank no domains predicted signal peptide no TMHs; hypothetical protein	2708500..2709174	Azoarcus sp. BH72	4607422
YP_933959.1	CDS	rcp2	NC_008702.1	2709188	2709628	R	Putative two-component response regulator,; Specificity unclear; putative two-component response regulator	complement(2709188..2709628)	Azoarcus sp. BH72	4607423
YP_933960.1	CDS	cph1	NC_008702.1	2709625	2711352	R	Putative two-component system sensor protein,; Function unclear; putative two-component system sensor protein	complement(2709625..2711352)	Azoarcus sp. BH72	4609697
YP_933961.1	CDS	azo2457	NC_008702.1	2711355	2713823	R	Putative sensory box histidine kinase,; Function unclear; putative sensory box histidine kinase	complement(2711355..2713823)	Azoarcus sp. BH72	4608526
YP_933962.1	CDS	azo2458	NC_008702.1	2714039	2714560	R	Putative transcriptional regulator, LuxR family,very low similarity to SWISSPROT: sprot|NARP_ECOLI (16% Escherichia coli, NarP) InterPro: IPR000792 HTH_LuxR. Pfam: PF00196 GerE. Signal P reporting signal peptide. HTH reporting nucleic acid binding motif.; Function unclear; LuxR family transcriptional regulator	complement(2714039..2714560)	Azoarcus sp. BH72	4607424
YP_933963.1	CDS	azo2459	NC_008702.1	2715013	2716176	D	Hypothetical protein, has very weak homolgy with hits in the database. NO motifs,domains, signal peptide or TMH present.; hypothetical protein	2715013..2716176	Azoarcus sp. BH72	4607425
YP_933964.1	CDS	azo2460	NC_008702.1	2716200	2717258	D	Conserved hypothetical protein. Homology to mll6891 of Mesorhizobium loti of 37% (gi|14026496|dbj|BAB53093.1|). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2716200..2717258	Azoarcus sp. BH72	4607426
YP_933965.1	CDS	azo2461	NC_008702.1	2717280	2718590	D	Conserved hypothetical protein. Homology to mll6889 of M.loti. of 58% (trembl|Q987V8(SRS)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2717280..2718590	Azoarcus sp. BH72	4607427
YP_933966.1	CDS	azo2462	NC_008702.1	2718645	2720618	D	Hypothetical secreted protein. No homology of the entire protein to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	2718645..2720618	Azoarcus sp. BH72	4607428
YP_933967.1	CDS	azo2463	NC_008702.1	2720645	2721274	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	2720645..2721274	Azoarcus sp. BH72	4607429
YP_933968.1	CDS	azo2464	NC_008702.1	2721255	2722364	D	Conserved hypothetical protein. Homology to mll6883 of M.loti of 58% (trembl|Q987W1(SRS)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2721255..2722364	Azoarcus sp. BH72	4607430
YP_933969.1	CDS	azo2465	NC_008702.1	2722381	2723358	D	Hypothetical protein. No homology to the data base. No domains predicted. No signal peptide. No TMHs.; hypothetical protein	2722381..2723358	Azoarcus sp. BH72	4607431
YP_933970.1	CDS	azo2466	NC_008702.1	2723377	2724144	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2723377..2724144	Azoarcus sp. BH72	4607432
YP_933971.1	CDS	azo2467	NC_008702.1	2724141	2725190	D	Conserved hypothetical protein. Homology to mll6881 of M.loti of 49% (trembl|Q987W3(SRS)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2724141..2725190	Azoarcus sp. BH72	4607433
YP_933972.1	CDS	azo2468	NC_008702.1	2725351	2726754	D	Conserved hypothetical transcriptional regulator. Homology to pp3544 of P. putida of 56% (trembl|Q88H21). InterPro: Aminotransferases class-I (IPR004838); Bacterial regulatory proteins, GntR family (IPR000524). Pfam: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II. no signal peptide. no TMHs; Family membership; putative transcriptional regulator	2725351..2726754	Azoarcus sp. BH72	4607434
YP_933973.1	CDS	azo2469	NC_008702.1	2726765	2727181	R	Conserved hypothetical protein. Homology to bb1298 of B. brochiseptica of 64% (trembl|Q7WMU2). Pfam: Glyoxalase/Bleomycin restiant protein. no signal peptide. no TMHs; hypothetical protein	complement(2726765..2727181)	Azoarcus sp. BH72	4607435
YP_933974.1	CDS	lldD	NC_008702.1	2727286	2728407	R	Conserved hypothetical L-lactate dehydrogenase (cytochrome). Homology to lldD of B. bronchisptica of 51% (tremble:Q7WND1). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009). Pfam: FMN-dependent dehydrognease. no signal peptide. no TMHs; Family membership; L-lactate dehydrogenase	complement(2727286..2728407)	Azoarcus sp. BH72	4607436
YP_933975.1	CDS	panE1	NC_008702.1	2728444	2729406	R	Ketopantoate reductase (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). TIGRFAM: apbA_panE: 2-dehydropantoate 2-reductase Pfam: ApbA: Ketopantoate reductase PanE/ApbA; High confidence in function and specificity; 2-dehydropantoate 2-reductase	complement(2728444..2729406)	Azoarcus sp. BH72	4609165
YP_933976.1	CDS	dctP4	NC_008702.1	2729490	2730527	R	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 22% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present. TMHelix:1; High confidence in function and specificity; putative C4-dicarboxylate-binding periplasmic protein	complement(2729490..2730527)	Azoarcus sp. BH72	4609495
YP_933977.1	CDS	xylC	NC_008702.1	2730630	2732087	R	Probable benzaldehyde dehydrogenase [NAD+] (EC 1.2.1.28). Homology to xylC of P. putida of 53% (sprot|XYLC_PSEPU). CATALYTIC ACTIVITY: Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH. Interpro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs proA: gamma-glutamyl phosphate reductas; Family membership; benzaldehyde dehydrogenase	complement(2730630..2732087)	Azoarcus sp. BH72	4608605
YP_933978.1	CDS	alsS	NC_008702.1	2732140	2733846	R	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit	complement(2732140..2733846)	Azoarcus sp. BH72	4610132
YP_933979.1	CDS	dntR	NC_008702.1	2733998	2734894	R	Transcriptional regulator,; High confidence in function and specificity; LysR family transcriptional regulator	complement(2733998..2734894)	Azoarcus sp. BH72	4608307
YP_933980.1	CDS	rdxA	NC_008702.1	2735125	2736588	D	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to rdxA of R. sphaeroides of 37% (SWISSPROT:RDXA_RHOSH) Involved in a membrane generated redox signal. Pfam: 4Fe-4S binding domain Probable 5 TMHs no signal peptide; Family membership; putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein	2735125..2736588	Azoarcus sp. BH72	4608642
YP_933981.1	CDS	azo2477	NC_008702.1	2737170	2737286	R	Putative hypothetical protein. Has extremely weak homologs in the the database. No signaficant known doamins,motifs or signal peptide present.; hypothetical protein	complement(2737170..2737286)	Azoarcus sp. BH72	4609700
YP_933982.1	CDS	azo2478	NC_008702.1	2737435	2738619	D	Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. 34% MFS.IPR005829; Sug_transporter.IPR010916;TONB_Box_N. TMHelix:9.; Function unclear; putative MFS transporter permease	2737435..2738619	Azoarcus sp. BH72	4607437
YP_933983.1	CDS	azo2479	NC_008702.1	2738628	2739335	R	Conserved hypothetical membrane protein. Homology to VV12384 of Vibrio vulnificus of 60% (trembl|Q8DA26). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(2738628..2739335)	Azoarcus sp. BH72	4607438
YP_933984.1	CDS	azo2480	NC_008702.1	2739453	2739998	R	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	complement(2739453..2739998)	Azoarcus sp. BH72	4607439
YP_933985.1	CDS	azo2481	NC_008702.1	2740029	2740652	D	Conserved hypothetical membrane protein,; Conserved hypothetical protein; hypothetical protein	2740029..2740652	Azoarcus sp. BH72	4607440
YP_933986.1	CDS	azo2482	NC_008702.1	2740640	2745688	R	Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Conserved hypothetical protein; putative hybrid sensor and regulator	complement(2740640..2745688)	Azoarcus sp. BH72	4607441
YP_933987.1	CDS	azo2483	NC_008702.1	2745706	2746377	R	Conserved hypothetical secreted protein. Homology to Magn03007875 of Magnetospirillum magnetotacticum of 31% (gi|46202369|ref|ZP_00208493.1|(NBCI ENTREZ)). No domains predicted. Signal Peptide is reported to be Present, by Signal P program. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(2745706..2746377)	Azoarcus sp. BH72	4607442
YP_933988.1	CDS	azo2484	NC_008702.1	2746361	2747515	R	Putative response regulator,; Family membership; putative response regulator	complement(2746361..2747515)	Azoarcus sp. BH72	4607443
YP_933989.1	CDS	azo2485	NC_008702.1	2747681	2747938	R	Conserved hypothetical protein. Homology to eca2717 of E. carotovora of 35% (tremble:Q6D3M7). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2747681..2747938)	Azoarcus sp. BH72	4607444
YP_933990.1	CDS	ppsA2	NC_008702.1	2747955	2750558	R	Phosphoenolpyruvate synthase(Pyruvatewater dikinase)(PEP synthase). Essential step in gluconeogenesis when pyruvate and lactate are used as a carbon source.Catalytic activity:atp + pyruvate + h(2)o = amp + phosphoenolpyruvate + phosphate. 25% PEP_mobile.IPR006319; PEP_synth.IPR000121;PEP_utilizers.IPR002192; PPDK_N_term. Pfam:PF00391; PEP-utilizers; 1.PF02896; PEP-utilizers_C; 1. PF01326; PPDK_N; 1. TIGRFAMs:TIGR01418; PEP_synth; 1.; High confidence in function and specificity; putative phosphoenolpyruvate synthase	complement(2747955..2750558)	Azoarcus sp. BH72	4607445
YP_933991.1	CDS	azo2487	NC_008702.1	2750555	2751166	R	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	complement(2750555..2751166)	Azoarcus sp. BH72	4609616
YP_933992.1	CDS	azo2488	NC_008702.1	2751342	2751662	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2751342..2751662)	Azoarcus sp. BH72	4607446
YP_933993.1	CDS	azo2489	NC_008702.1	2751828	2753672	R	Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions(sodium symporters). Hypothetical E.coli protein yfbS. Similar to TrkA. The NAD+ -binding protein TrkA is a component of a low-affinity K+ uptake system in Escherichia coli. This protein has the TrkA-C and TrkA-N domains. dass: anion transporter; High confidence in function and specificity; putative transport protein	complement(2751828..2753672)	Azoarcus sp. BH72	4607447
YP_933994.1	CDS	txn	NC_008702.1	2753758	2754147	R	Putative Thioredoxin. Homology to txn (THIO_ICTPU) of I. punctatus of 36%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin (IPR0006662) Tigrfam: dsbE: periplasmic protein thiol:disulfie Oxidoreductase, DSB subfamily Pfam: Thioredoxin no signal peptide no TMHs; Family membership; thioredoxin-disulfide reductase	complement(2753758..2754147)	Azoarcus sp. BH72	4607448
YP_933995.1	CDS	etfA3	NC_008702.1	2754465	2755391	R	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 65% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity; electron transfer flavoprotein subunit alpha	complement(2754465..2755391)	Azoarcus sp. BH72	4610052
YP_933996.1	CDS	etfB3	NC_008702.1	2755391	2756140	R	Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity; electron transfer flavoprotein subunit beta	complement(2755391..2756140)	Azoarcus sp. BH72	4608680
YP_933997.1	CDS	azo2493	NC_008702.1	2756182	2756715	R	Entry name:- TREMBL:Q8XXS1 InterPro IPR002539; MaoC_dehydratas. Pfam PF01575; MaoC_dehydratas; 1. Identities = 74/154 (48%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; hypothetical protein	complement(2756182..2756715)	Azoarcus sp. BH72	4608684
YP_933998.1	CDS	aidB2	NC_008702.1	2756715	2758502	R	The aidB gene encodes a protein of ca. 60 kDa that is homologous to several mammalian acyl coenzyme A dehydrogenases. Reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor Entry name SWISSPROT:AIDB_ECOLI InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 85/289 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; putative acyl-CoA dehydrogenase	complement(2756715..2758502)	Azoarcus sp. BH72	4607449
YP_933999.1	CDS	fcbC1	NC_008702.1	2758926	2759345	R	4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23). This family contains a wide variety of enzymes,principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3 InterPro:IPR008272; 4HBcoA_thiost_AS. IPR006683; Thioestr_supf. Pfam:PF03061; 4HBT InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site No signal peptide No transmembrane helices TIGR00051: conserved hypothetical protein; High confidence in function and specificity; thiesterase	complement(2758926..2759345)	Azoarcus sp. BH72	4608290
YP_934000.1	CDS	azo2496	NC_008702.1	2759364	2760131	R	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear; short-chain dehydrogenase	complement(2759364..2760131)	Azoarcus sp. BH72	4608735
YP_934001.1	CDS	paaJ2	NC_008702.1	2760328	2761587	R	Thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA (By similarity). Entry name PAAJ_ECOLI Primary accession number P77525 Identity: 150/410 (36%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; putative beta-ketoadipyl CoA thiolase	complement(2760328..2761587)	Azoarcus sp. BH72	4607450
YP_934002.1	CDS	paaG3	NC_008702.1	2761584	2762369	R	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	complement(2761584..2762369)	Azoarcus sp. BH72	4609482
YP_934003.1	CDS	fadD2	NC_008702.1	2762390	2764258	R	catalyzes the conversion of ferulic acid to feruloyl-CoA; feruloyl-CoA synthase	complement(2762390..2764258)	Azoarcus sp. BH72	4609474
YP_934004.1	CDS	livK2	NC_008702.1	2764287	2765432	R	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar sprot|LIVK_ECOLI (21%) and to trembl|Q9RYP6 (50%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative leucine-specific binding protein	complement(2764287..2765432)	Azoarcus sp. BH72	4608723
YP_934005.1	CDS	azo2501	NC_008702.1	2765867	2766628	R	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q8XRX4 (66%) and to trembl|Q89PQ7 (62%). Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	complement(2765867..2766628)	Azoarcus sp. BH72	4609154
YP_934006.1	CDS	azo2502	NC_008702.1	2766628	2768421	R	Probable branched-chain amino acid ABC transporterATP binding protein,; Specificity unclear; branched-chain amino acid ABC transporter	complement(2766628..2768421)	Azoarcus sp. BH72	4607451
YP_934007.1	CDS	azo2503	NC_008702.1	2768487	2769524	R	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q7W5E8 (62%), to sprot|BRAD_PSEAE (25%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting nine Tmhelix.; Specificity unclear; ABC transporter permease	complement(2768487..2769524)	Azoarcus sp. BH72	4607452
YP_934008.1	CDS	azo2504	NC_008702.1	2769967	2770881	D	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	2769967..2770881	Azoarcus sp. BH72	4607453
YP_934009.1	CDS	azo2505	NC_008702.1	2771064	2771702	D	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	2771064..2771702	Azoarcus sp. BH72	4607454
YP_934010.1	CDS	cmd	NC_008702.1	2771799	2772377	D	Conserved hypothetical protein. The highly identitcal hits such as Hypothetical Proteins of TrEMBL;Q8XXB7,Q6N0V6(80% identity) do not share all the domains as this Protein. Has Carboxymuconolactone decarboxylase family;IPR003779, CMD:The catechol and protocatechuate branches of the 3-oxoadipate pathway,which areimportant for the bacterial degradation of aromatic compounds, converge at the common intermediate 3-oxoadipate enol-lactone. Carboxymuconolactone decarboxylase is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway.; Specificity unclear; 4-carboxymuconolactone decarboxylase	2771799..2772377	Azoarcus sp. BH72	4607455
YP_934011.1	CDS	azo2507	NC_008702.1	2772486	2772884	R	Hypothetical membrane protein. no homology of the entire protein to the data bank. no domains predicted. no signal peptide. 2 TMHS; hypothetical protein	complement(2772486..2772884)	Azoarcus sp. BH72	4608494
YP_934012.1	CDS	azo2508	NC_008702.1	2772945	2773253	R	Conserved hypothetical protein. Homology to Daro03003856 of Dechloromonas aromatica of 41% (gi|46140330|ref|ZP_00203564.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2772945..2773253)	Azoarcus sp. BH72	4607456
YP_934013.1	CDS	azo2509	NC_008702.1	2773297	2775222	R	Conserved hypothetical protein. Homology to cv0086 of C. violaceum of 76% (trembl|Q7P1X6). no signal peptide. no TMHs. No domains reported.; hypothetical protein	complement(2773297..2775222)	Azoarcus sp. BH72	4607457
YP_934014.1	CDS	azo2510	NC_008702.1	2775497	2775781	R	Bacterial ring hydroxylating dioxygenase,small subunit. Similar to AlcE: iron-sulfur-containing dioxygenases, probably involved in alcaligin biosynthesis pathway in Bordetella species. Putative iron-sulfure protein involved in aromatic compounds degradations. Rieske [2Fe-2S] domain present. Probable Choline monooxygenase chloroplast precursor (EC 1.14.15.7). nadp_idh_euk: isocitrate dehydrogenase; Function unclear; putative iron-sulfur protein	complement(2775497..2775781)	Azoarcus sp. BH72	4607458
YP_934015.1	CDS	fpvA1	NC_008702.1	2776065	2778491	R	Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity; putative TonB-dependent receptor	complement(2776065..2778491)	Azoarcus sp. BH72	4607459
YP_934016.1	CDS	azo2512	NC_008702.1	2778614	2779630	R	Probable FecR-like transmembrane sensor involved in iron metabolism. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm.; High confidence in function and specificity; putative transmembrane sensor	complement(2778614..2779630)	Azoarcus sp. BH72	4608827
YP_934017.1	CDS	azo2513	NC_008702.1	2779714	2780268	R	Probable fecI-like RNA polymerase sigma factor. THE SIGMA FACTOR IS AN INITIATION FACTOR THAT PROMOTES ATTACHMENT OF THE RNA POLYMERASE TO SPECIFIC INITIATION SITES AND THEN IS RELEASED. THIS SIGMA FACTOR REGULATES THE FEC GENES FOR IRON DICITRATE TRANSPORT (PROBABLE). InterPro: Sigma factor ECF subfamily; Specificity unclear; RNA polymerase ECF-subfamily sigma factor	complement(2779714..2780268)	Azoarcus sp. BH72	4607460
YP_934018.1	CDS	nagAb	NC_008702.1	2780947	2781264	R	Naphthalene 12-dioxygenase system ferredoxin component. COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP).; High confidence in function and specificity; putative ferredoxin	complement(2780947..2781264)	Azoarcus sp. BH72	4607461
YP_934019.1	CDS	nagH	NC_008702.1	2781315	2781818	R	NagH: probable salicylate-5-hydroxylase small oxygenase component oxidoreductase. Involved in conversion of Naphthalene to gentisate. Aromatic compounds degradation.; Family membership; putative ring hydroxylating subunit beta	complement(2781315..2781818)	Azoarcus sp. BH72	4609308
YP_934020.1	CDS	nagG	NC_008702.1	2781815	2783131	R	nagG,RSc1090:putative salicylate-5-hydroxylase large oxygenase component oxidoreductase [EC:1.-.-.-]. Rieske-type iron-sulfur center homologous to the large subunits of dihydroxylating dioxygenases. Involved in conversion of Naphthalene to gentisate. Aromatic compounds degradation. Biphenyl dioxygenase alpha subunit (EC 1.14.12.18) (Biphenyl 23- dioxygenase).; High confidence in function and specificity; putative ring hydroxylating large subunit	complement(2781815..2783131)	Azoarcus sp. BH72	4609310
YP_934021.1	CDS	nagAa	NC_008702.1	2783542	2784528	R	Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH.; High confidence in function and specificity; naphthalene 1,2-dioxygenase/ferredoxin--NAD(+) reductase	complement(2783542..2784528)	Azoarcus sp. BH72	4609309
YP_934022.1	CDS	nahR2	NC_008702.1	2784640	2785581	D	LysR-type transcriptional regulator NahR Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes. Similar to SWISSPROT: sprot|NAHR_PSEPU (61% Pseudomonas putida, nahR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; LysR family transcriptional regulator	2784640..2785581	Azoarcus sp. BH72	4609307
YP_934023.1	CDS	dctM5	NC_008702.1	2785687	2787012	R	TRAP-type C4-dicarboxylate transport system, large permease component,DctM. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 25% DctM.IPR000252; DedA.IPR000524; HTH_GntR.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. TMHelix: 11.; Specificity unclear; TRAP-type C4 dicarboxylate transport system large permease	complement(2785687..2787012)	Azoarcus sp. BH72	4609325
YP_934024.1	CDS	azo2520	NC_008702.1	2787009	2787533	R	Conserved hypothetical membrane protein. Homology to PM1526 of Pasteurella multocida of 32% (trembl|Q9CKT0(SRS)). Pfam: PF04290;IPR007387;Tripartite ATP-independent periplasmic transporters, DctQ component; The function of the members of this family is unknown, but DctQ homologues are invariably found in the tripartite ATP-independent periplasmic transporters. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2787009..2787533)	Azoarcus sp. BH72	4608601
YP_934025.1	CDS	dctP5	NC_008702.1	2787622	2788647	R	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear; putative C4-dicarboxylate-binding periplasmic protein	complement(2787622..2788647)	Azoarcus sp. BH72	4607462
YP_934026.1	CDS	ligB1	NC_008702.1	2788910	2789752	R	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway; protocatechuate 4,5-dioxygenase subunit beta	complement(2788910..2789752)	Azoarcus sp. BH72	4608606
YP_934027.1	CDS	ligA1	NC_008702.1	2789756	2790106	R	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway; protocatechuate 4,5-dioxygenase subunit alpha	complement(2789756..2790106)	Azoarcus sp. BH72	4609141
YP_934028.1	CDS	pnbR	NC_008702.1	2790194	2791156	D	Transcriptional regulator, LysR family,; Specificity unclear; LysR family transcriptional regulator	2790194..2791156	Azoarcus sp. BH72	4609139
YP_934029.1	CDS	azo2525	NC_008702.1	2791543	2793033	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. Pfam: Endo/excinuclease amino terminal domain. no signal peptide. no TMHs. HTH predicted; hypothetical protein	2791543..2793033	Azoarcus sp. BH72	4609588
YP_934030.1	CDS	pobR2	NC_008702.1	2793435	2794322	R	Transcriptional regulator, AraC family,; High confidence in function and specificity; AraC family transcriptional regulator	complement(2793435..2794322)	Azoarcus sp. BH72	4607463
YP_934031.1	CDS	azo2527	NC_008702.1	2794548	2795711	D	Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450.; Family membership; cytochrome P450 family protein	2794548..2795711	Azoarcus sp. BH72	4609595
YP_934032.1	CDS	fdxP	NC_008702.1	2795797	2796120	D	Probable ferredoxin. Homology to fdxP of C. crescentus of 51% (sprot|FER2_CAUCR). Ferredons are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: Ferredoxin (IPR001041),Adrenodoxin (IPR001055) Pfam: 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity; ferrodoxin	2795797..2796120	Azoarcus sp. BH72	4607464
YP_934033.1	CDS	camA	NC_008702.1	2796181	2797398	D	Probable putidaredoxin reductase (EC 1.18.1.-). Homology to camA of P. putida of 48% (sprot|CAMA_PSEPU). The oxidation of camphor by cytochrome p450-cam requires the participation of a flavoprotein, putidaredoxin reductase, and an iron-sulfur protein, putidaredoxin, to mediate the transfer of electrons from nadh to p450 for oxygen activation. Interpro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IRP001327), NAD binding site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership; putidaredoxin reductase	2796181..2797398	Azoarcus sp. BH72	4608752
YP_934034.1	CDS	azo2530	NC_008702.1	2797558	2798433	D	Hypothetical protein yqgX. 65% identity, 75% similarity to conserved hypothetical protein (TREMBL:Q7P219) InterPro; TREMBL:Q7WQV2; Metallo-beta-lactamase superfamily. Pfam: Aminotransferase class III; helper component proteinase TREMBL:Q9DCMO-RIKEN cDNA; TREMBL:Q9A911 - GlyoxlaseII superfamily protein. TIGR00162: conserved hypothetical protein. Signal peptide-nonsecretory protein; Transmembrane helices present.; Function unclear; hypothetical protein	2797558..2798433	Azoarcus sp. BH72	4608412
YP_934035.1	CDS	azo2531	NC_008702.1	2798436	2799140	R	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; glutamine amidotransferase	complement(2798436..2799140)	Azoarcus sp. BH72	4607465
YP_934036.1	CDS	azo2532	NC_008702.1	2799319	2799741	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2799319..2799741	Azoarcus sp. BH72	4607466
YP_934037.1	CDS	fliC1	NC_008702.1	2799878	2801560	D	Flagellin (Phase-1-D flagellin). Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus,Flagellin C-terminus Pfam: Bacterial flagellin N-terminus,bacterial flagellin C-terminus no signal peptide no TMH; Family membership; putative flagellin	2799878..2801560	Azoarcus sp. BH72	4607467
YP_934038.1	CDS	mdcF2	NC_008702.1	2801557	2802510	R	Putative malonate transporter. TREMBL:Q7ML40: 38% identity, 55% similarity SPROT:P56949: 27% identity, 44% similarity subcellular location:integral membrane protein (potential). similarity:belongs to the auxin efflux carrier (tc 2.a.69) family. InterPro:IPR004776; Auxin_eff. Pfam: PF03547; Auxin_eff; GntP_permease;GntP family permease (Pfam) 2a69: Auxin Efflux Carrier Signal P predicted signal peptide and TMHMM predicted 10 transmembrane helices; Specificity unclear; putative malonate transporter	complement(2801557..2802510)	Azoarcus sp. BH72	4608795
YP_934039.1	CDS	yakC	NC_008702.1	2802611	2803606	R	Probable aldo-keto reductase. Homology to yakC of S.pombe of 43% (sprot|YAKC_SCHPO). Catalyze the reduction of 2-nitorbenzaldehyde, pyridine-2-aldehyde and 2-phthaladehyde. Pfam: Aldo/Keto reductase signal peptide no TMHs; Family membership; aldo-keto reductase	complement(2802611..2803606)	Azoarcus sp. BH72	4609202
YP_934040.1	CDS	ligC	NC_008702.1	2804153	2805112	R	Hypothetical oxidoreductase yrbE (EC 1.-.-.-). TREMBL:Q93PS4:90% identity; 93% similarity. This group of enzymes utilise NADP or NAD, and is known as the GFO/IDH/MOCA family in Swiss-Prot. GFO is a glucose--fructose oxidoreductase, which converts D-glucose and D-fructose into D-gluconolactone and D-glucitol in the sorbitol-gluconate pathway. MOCA is a rhizopine catabolism protein which may catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine catabolism. Other proteins belonging to this family include Gal80, a negative regulator for the expression of lactose and galactose metabolic genes; and several hypothetical proteins from yeast, Escherichia coli and Bacillus subtilis. InterPro:IPR000683; GFO_IDH_MocA. IPR004104; GFO_IDH_MocA_C. Pfam: PF01408; GFO_IDH_MocA; 1. PF02894; GFO_IDH_MocA_C; presence of DUF206 Probably nonsecretory protein (SignalP predicted) Number of predicted TMHs: 0 (TMHMM predicted) InterPro: Oxidoreductase N-terminal ubiX: phenylacrylic acid decarboxylase 3; High confidence in function and specificity; oxidoreductase	complement(2804153..2805112)	Azoarcus sp. BH72	4610142
YP_934041.1	CDS	ligB2	NC_008702.1	2805209	2806063	R	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway; protocatechuate 4,5-dioxygenase subunit beta	complement(2805209..2806063)	Azoarcus sp. BH72	4609143
YP_934042.1	CDS	ligA2	NC_008702.1	2806066	2806506	R	extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway; protocatechuate 4,5-dioxygenase subunit alpha	complement(2806066..2806506)	Azoarcus sp. BH72	4609142
YP_934043.1	CDS	ligI	NC_008702.1	2807012	2807926	R	Probable 2-pyrone-4,6-dicarboxylate hydrolase. Homology to ligI of S. paucimobilis of 55% (tremble:O87170) Pfam: Amidohydrolase no signal peptide no TMHs; High confidence in function and specificity; 2-pyrone-4,6-dicarboxylate hydrolase	complement(2807012..2807926)	Azoarcus sp. BH72	4609140
YP_934044.1	CDS	mmsB	NC_008702.1	2807967	2808902	R	Activity:- 3-hydroxy-2-methylpropanoate + NAD = 2-methyl-3-oxopropanoate + NADH2 Entry name SWISSPROT:MMSB_PSEAE InterPro IPR002204; 3hydroxisobut_dh. IPR006115; 6PGD_NAD. Pfam PF03446; NAD_binding_2; 1. Identities = 48/218 (22%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; putative 3-hydroxyisobutyrate dehydrogenase	complement(2807967..2808902)	Azoarcus sp. BH72	4609144
YP_934045.1	CDS	azo2541	NC_008702.1	2808905	2809594	R	Possible acyl transferase.; Family membership; hypothetical protein	complement(2808905..2809594)	Azoarcus sp. BH72	4609231
YP_934046.1	CDS	fldW	NC_008702.1	2809613	2810638	R	4-oxalomesaconate hydratase These proteins are related to the metal-dependent hydrolase superfamily tremblnew|CAE30137: 86% identity, 93% similarity InterPro:IPR006992; Amidohydro_2. Pfam:PF04909; Amidohydro_2 Absence of traansmembrane helices (TMHMM predicted); High confidence in function and specificity; 4-oxalomesaconate hydratase	complement(2809613..2810638)	Azoarcus sp. BH72	4607468
YP_934047.1	CDS	pcaK	NC_008702.1	2810683	2812047	R	PcaK:4-hydroxybenzoate transporter. TRANSPORTER FOR 4-HYDROXYBENZOATE ALSO REQUIRED FOR CHEMOTAXIS TO AROMATIC ACIDS. Membership of the major facilitator superfamily of transport proteins. 2A0115: benzoate transport; High confidence in function and specificity; putative 4-hydroxybenzoate transporter protein	complement(2810683..2812047)	Azoarcus sp. BH72	4608772
YP_934048.1	CDS	fldA	NC_008702.1	2812166	2813248	R	Hypothetical protein FldA, 78% identity (86% similarity) to TrEMBL;Q6N0R5,Q8PF30(47% identity). 45% identity to ybhH of SwissProt;P75762(E.coli) Has PF04303,Protein of unknown function (DUF453);IPR007400; FldA (Q9L3A0) is thought to be involved in the degradation of the polyaromatic hydrocarbon fluorene by Sphingomonas sp. LB126. Has PF01678, Diaminopimelate epimerase;IPR001653 DAP_epimerase: Diaminopimelate epimerase contains two domains of the same alpha/beta fold, both contained in this family.Diaminopimelate epimerase (EC:5.1.1.7) catalyzes the isomeriazation of L,L- to D,L-meso-diaminopimelate in the biosynthetic pathway leading from aspartate to lysine. This enzyme is a protein of about 30 kDa. No signal peptide or TMH present.; Family membership; hypothetical protein	complement(2812166..2813248)	Azoarcus sp. BH72	4609505
YP_934049.1	CDS	bcr1	NC_008702.1	2813370	2814611	R	Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General substrate transporters efflux_Bcr_CflA: drug resistance tran Also show similarity to bssH of bssDCABEFGH operon-genes involved in anaerobic degradation of toulene in denitryfing bacterium, Azoarcus strain EbN1; High confidence in function and specificity; putative bicyclomycin resistance protein	complement(2813370..2814611)	Azoarcus sp. BH72	4608771
YP_934050.1	CDS	nac	NC_008702.1	2814613	2815779	D	Nitrogen assimilation regulatory protein nac (Nitrogen assimilation control protein). TRANSCRIPTIONAL ACTIVATOR FOR THE HUT PUT AND URE OPERONS AND REPRESSOR FOR THE GDH AND GLTB OPERONS IN RESPONSE TO NITROGEN LIMITATION. NEGATIVE REGULATOR OF ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|NAC_KLEAE (30% Klebsiella aerogenes, nitrogen assimilation regulatory protein nac (nitrogen assimilation control protein)) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Specificity unclear; putative nitrogen assimilation regulatory protein	2814613..2815779	Azoarcus sp. BH72	4608382
YP_934051.1	CDS	azo2547	NC_008702.1	2815984	2817636	D	Probable methyl-accepting chemotaxis protein,; Specificity unclear; methyl-accepting chemotaxis protein	2815984..2817636	Azoarcus sp. BH72	4609301
YP_934052.1	CDS	dyp	NC_008702.1	2817706	2818587	R	Getrichum candidum Dec1,Dye-decolorizing peroxidase,DyP, that lacks a typical heme-binding region. Responsible for the decoloration of dyes. DyP degraded phenolic compounds, such as 2,6-dimethoxyphenol and guaiacol. Hypothetical protein yfeX. ccoO: cytochrome c oxidase cbb3-type su; High confidence in function and specificity; putative iron-dependent peroxidase	complement(2817706..2818587)	Azoarcus sp. BH72	4607469
YP_934053.1	CDS	cca2	NC_008702.1	2818660	2819562	R	tRNA nucleotidyltransferase (EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA CCA-pyrophosphorylase) (CCA-adding enzyme). This enzyme carries out synthesis of the tRNA CCA terminus without the direction of a template using the multiple accepting and donating subsites within its active site.; Family membership; tRNA nucleotidyltransferase	complement(2818660..2819562)	Azoarcus sp. BH72	4608660
YP_934054.1	CDS	mdcF3	NC_008702.1	2819724	2820674	D	Putative malonate transporter. TREMBL:Q8ZCU0: 38% identity, 55% similarity SPROT:P56949:23% identity, 41% similarity InterPro:IPR004776; Auxin_eff. Pfam:PF03547; Auxin_ef Signal P predicted nonsecretory protein and TMHMM predicted 9 transmembrane helices. 2a69: Auxin Efflux Carrier; Specificity unclear; putative malonate transporter	2819724..2820674	Azoarcus sp. BH72	4608442
YP_934055.1	CDS	azo2551	NC_008702.1	2821091	2821981	D	Conserved hypothetical membrane protein. Homology with PA3897 of P. aeruginosa of 30%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transport. Pfam: Integral membrane protein DUF6. probable 10 TMHs. no signal peptide; Conserved hypothetical protein; hypothetical protein	2821091..2821981	Azoarcus sp. BH72	4609203
YP_934056.1	CDS	pilU1	NC_008702.1	2822144	2823451	D	Tfp pilus retraction protein PilU, probable involved in the twitching motility mechanism,; High confidence in function and specificity; twitching motility protein	2822144..2823451	Azoarcus sp. BH72	4607470
YP_934057.1	CDS	azo2553	NC_008702.1	2823562	2824104	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide; hypothetical protein	2823562..2824104	Azoarcus sp. BH72	4609574
YP_934058.1	CDS	nodT	NC_008702.1	2824434	2825978	D	Putative outer membrane efflux protein. Homology to nodT from Rhizobium leguminosarum of 20% over 432 aa. The OEP family (Outer membrane efflux protein)allow export of a variety of substrates in Gram negative bacteria. Most members of NodT family are likely to export primarily small molecules rather than proteins. InterPro: Outer membrane efflux protein. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership; putative outer membrane efflux protein	2824434..2825978	Azoarcus sp. BH72	4607471
YP_934059.1	CDS	azo2555	NC_008702.1	2825984	2826748	D	Specificity unclear; HlyD family secretion protein	2825984..2826748	Azoarcus sp. BH72	4609392
YP_934060.1	CDS	azo2556	NC_008702.1	2826820	2832576	D	No Good Homology with any hits in the DB. Conserved Hypothetical Protein,34% similarity to TrEMBL;Q8E9W3. Has PF03160:IPR003644:Calx_beta;Na-Ca exchanger/integrin-beta4:This domain has been found in Na-Ca exchangers and integrin subunit beta4, as well as some cyanobacterial proteins. Has 3 CA(Cadherin repeats)domains;SMART:SM00112;IPR002126:Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium. Has 1 CADG,Dystroglycan-type cadherin-like domains(SMART;SM00736).Cadherin-homologous domains present in metazoan dystroglycans and alpha/epsilon sarcoglycans,yeast Axl2p and in a very large protein from magnetotactic bacteria. Likely to bind calcium ions.; Family membership; hypothetical protein	2826820..2832576	Azoarcus sp. BH72	4607472
YP_934061.1	CDS	azo2557	NC_008702.1	2832576	2833937	D	Similar to MacA.; Family membership; HlyD family secretion protein	2832576..2833937	Azoarcus sp. BH72	4607473
YP_934062.1	CDS	azo2558	NC_008702.1	2833940	2836051	D	Family membership; HlyD domain-containing protein	2833940..2836051	Azoarcus sp. BH72	4607474
YP_934063.1	CDS	azo2559	NC_008702.1	2836162	2836581	D	Conserved hypothetical secreted protein. Homology to Mflag03001539 of Methylobacillus flagellatus of 38% (gi|45521149|ref|ZP_00172671.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2836162..2836581	Azoarcus sp. BH72	4607475
YP_934064.1	CDS	azo2560	NC_008702.1	2836767	2837564	D	Conserved hypothetical protein. Homology to rsc1124 of R. solanacearum of 59% (trembl|Q8Y0C0). no signal peptide. no TMHs. no domains reported.; hypothetical protein	2836767..2837564	Azoarcus sp. BH72	4607476
YP_934065.1	CDS	azo2561	NC_008702.1	2837663	2839060	R	Conserved hypothetical protein. Homology to dr0392 of D. radiodurans of 33% (trembl|Q9RXC3). Pfam: Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. no signal peptide. no TMHs; hypothetical protein	complement(2837663..2839060)	Azoarcus sp. BH72	4607477
YP_934066.1	CDS	ccp	NC_008702.1	2839343	2840350	D	Cytochrome c peroxidase (EC 1.11.1.5), an electron-transfer proteins having one or several haem c groups,bound to the protein by one or, more generally, two thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. CytC possess a wide range of properties and function in a large number of different redox processes. Signal peptide.; High confidence in function and specificity; putative cytochrome c peroxidase	2839343..2840350	Azoarcus sp. BH72	4607478
YP_934067.1	CDS	azo2563	NC_008702.1	2840530	2840916	D	Conserved hypothetical secreted secreted protein. Homology to bb1301 of B. bronchiseptica of 59% (trembl|Q7WMT9). Pfam: Lipoprotein_15. This family occurs as tandem repeats in a set of lipoproteins. The alignment contains a Y-X4-D motif. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2840530..2840916	Azoarcus sp. BH72	4608459
YP_934068.1	CDS	azo2564	NC_008702.1	2840924	2841424	D	Putative RNA polymerase sigma factor,57% Identity to TrEMBL;Q7VV01, 49% Identity to TrEMBL;Q8XV48,53% to Q63LJ3. Has PF04542, Sigma-70 region 2; IPR007627,Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit,beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation. Has PF04545, Sigma-70, region 4;IPR007630, Sigma70_r4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.; putative RNA polymerase sigma factor	2840924..2841424	Azoarcus sp. BH72	4607479
YP_934069.1	CDS	azo2565	NC_008702.1	2841421	2842239	D	Conserved hypothetical membrane protein. Homology to BB1303 of Bordetella bronchiseptica of 50% (trembl|Q7WMT7). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present.; Conserved hypothetical protein; hypothetical protein	2841421..2842239	Azoarcus sp. BH72	4607480
YP_934070.1	CDS	azo2566	NC_008702.1	2842255	2843214	R	Hypothetical protein,53% identity to TrEMBL:Q8YF53,Hypothetical protein BMEI1674 [BMEI1674] [Brucella melitensis] Has IPR000157:TIR domain.; Family membership; ORF6; hypothetical protein	complement(2842255..2843214)	Azoarcus sp. BH72	4607481
YP_934071.1	CDS	azo2567	NC_008702.1	2843306	2844313	R	Putative LysR-family transcriptional regulator protein.62% identity to TrEMBL;Q63NK9,Q8XQV8,Q62B59,Q8VL17. PF00126, Bacterial regulatory helix-turn-helix protein, lysR family;IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse,but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB,lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR,pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini. Has PF03466, LysR substrate binding domain; IPR005119, LysR_subst; The structure of this domain is known and is; LysR family transcriptional regulator	complement(2843306..2844313)	Azoarcus sp. BH72	4607482
YP_934072.1	CDS	azo2568	NC_008702.1	2844563	2845765	D	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership; membrane fusion protein	2844563..2845765	Azoarcus sp. BH72	4607483
YP_934073.1	CDS	azo2569	NC_008702.1	2845776	2848967	D	AcrB/AcrD/AcrF family protein. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q92U15 (38% identity); TREMBL:Q7NE92 (38% identity). InterPro (IPR000731): Sterol-sensing 5TM box. InterPro (IPR004764): Hydrophobe/amphiphile efflux-1 HAE1. InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	2845776..2848967	Azoarcus sp. BH72	4607484
YP_934074.1	CDS	opcM2	NC_008702.1	2848984	2850510	D	Probable outer membrane efflux protein. Homology to opcM from B. cepacia of 40% Component of an efflux system that confers mutiple antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHS; Family membership; outer membrane efflux protein	2848984..2850510	Azoarcus sp. BH72	4607485
YP_934075.1	CDS	azo2571	NC_008702.1	2850539	2851069	R	Conserved hypothetical protein. Homology to VV1824 of V.vulnificus of 37% (trembl:Q7MKG9). No domains predicted. No signal peptide or TMH reported present.; hypothetical protein	complement(2850539..2851069)	Azoarcus sp. BH72	4609452
YP_934076.1	CDS	azo2572	NC_008702.1	2851066	2851710	R	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 1 TMHs; hypothetical protein	complement(2851066..2851710)	Azoarcus sp. BH72	4607486
YP_934077.1	CDS	fsr	NC_008702.1	2851794	2853032	R	A gene conferring resistance to fosmidomycin (Fs) encode a putative polypeptide of 406 amino acids (aa) with a molecular weight of 43303 in E.coli. 23% similarity to B. japonicum fsr. A comparison between the aa sequence of Fsr and sequences in a protein database revealed 18% homology to the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. Hydropathy analysis of the Fsr protein revealed twelve putative transmembrane segments. Fsr does not have any direct effect on the biosynthesis of isoprenoid in E. coli, and that the mechanism for FsR involves the efflux of the drug by a process that is facilitated by Fsr. (Ref: Fujisaki,S. et al., 1996); High confidence in function and specificity; putative fosmidomycin resistance protein	complement(2851794..2853032)	Azoarcus sp. BH72	4607487
YP_934078.1	CDS	azo2574	NC_008702.1	2853125	2853910	D	Putative AraC-family transcriptional regulator,; Family membership; AraC family transcriptional regulator	2853125..2853910	Azoarcus sp. BH72	4608831
YP_934079.1	CDS	gacS	NC_008702.1	2853962	2856457	R	Putative two-component hybrid sensor and regulator,; Family membership; putative two-component hybrid sensor and regulator	complement(2853962..2856457)	Azoarcus sp. BH72	4607488
YP_934080.1	CDS	dapB	NC_008702.1	2856467	2857276	R	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase	complement(2856467..2857276)	Azoarcus sp. BH72	4608854
YP_934081.1	CDS	omlA	NC_008702.1	2857314	2857823	R	Putative outer membrane lipoprotein OmlA precursor. Homology to omlA of P. aeruginosa of 33% (sprot|OMLA_PSEAE) MAY HAVE A STRUCTURAL ROLE IN MAINTAINING THE CELL ENVELOPE INTEGRITY. Pfam: SmpA/OmlA family no signal protein 1 TMH; Conserved hypothetical protein; putative outer membrane lipoprotein OmlA	complement(2857314..2857823)	Azoarcus sp. BH72	4608581
YP_934082.1	CDS	fur	NC_008702.1	2857844	2858281	D	Ferric uptake regulation protein (Ferric uptake regulator)Fur. Acts as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E. InterPro: Ferric uptake regulator family TIGR00011: conserved hypothetical protein; High confidence in function and specificity; putative ferric uptake regulation protein	2857844..2858281	Azoarcus sp. BH72	4609442
YP_934083.1	CDS	recN	NC_008702.1	2858307	2859974	R	DNA repair protein recN (Recombination protein N). MAY BE INVOLVED IN RECOMBINATIONAL REPAIR OF DAMAGED DNA. recN: DNA repair protein RecN; High confidence in function and specificity; DNA repair protein	complement(2858307..2859974)	Azoarcus sp. BH72	4608847
YP_934084.1	CDS	ppnK	NC_008702.1	2860012	2860896	R	Probable inorganic polyphosphate/ATP-NAD kinase(Poly(P)/ATP NAD kinase). Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. 34% ATP_NADK.InterPro: Domain of unknown function DUF15 Pfam:PF01513; NAD_kinase; 1. TIGR:VC0853.; High confidence in function and specificity; inorganic polyphosphate/ATP-NAD kinase	complement(2860012..2860896)	Azoarcus sp. BH72	4609708
YP_934085.1	CDS	hrcA	NC_008702.1	2861000	2862028	D	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor	2861000..2862028	Azoarcus sp. BH72	4609613
YP_934086.1	CDS	hemH	NC_008702.1	2862075	2863166	D	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase	2862075..2863166	Azoarcus sp. BH72	4609028
YP_934087.1	CDS	azo2583	NC_008702.1	2863166	2863522	D	Conserved hypothetical membrane protein. Homology to rs02279 of R. solanacearum of 53% (trembl|Q8Y388(SRS)). No domains predicted. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	2863166..2863522	Azoarcus sp. BH72	4608985
YP_934088.1	CDS	azo2584	NC_008702.1	2863580	2864590	D	Similar to TREMBL:Q7NTT5 (32% identity).; hypothetical protein	2863580..2864590	Azoarcus sp. BH72	4607489
YP_934089.1	CDS	yloP	NC_008702.1	2864625	2865989	R	Putative serine/threonine kinase,; Family membership; putative protein kinase	complement(2864625..2865989)	Azoarcus sp. BH72	4607490
YP_934090.1	CDS	azo2586	NC_008702.1	2866089	2866193	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2866089..2866193	Azoarcus sp. BH72	4610192
YP_934091.1	CDS	azo2587	NC_008702.1	2866190	2867509	D	Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; N-ethylammeline chlorohydrolase	2866190..2867509	Azoarcus sp. BH72	4607491
YP_934092.1	CDS	ompA1	NC_008702.1	2867629	2868345	D	Outer membrane protein P.III precursor (Gonococcal protein III) (PIII). InterPro: Bacterial outer membrane protein; High confidence in function and specificity; outer membrane protein A	2867629..2868345	Azoarcus sp. BH72	4607492
YP_934093.1	CDS	ubiG	NC_008702.1	2868451	2869152	D	Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase	2868451..2869152	Azoarcus sp. BH72	4609443
YP_934094.1	CDS	azo2590	NC_008702.1	2869577	2870845	R	Conserved hypothetical protein. Homology to ebA5327 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA5327(KEGG)). Pfam: Polysaccharide pyruvyl transferase Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. no signal peptide. no TMHs; hypothetical protein	complement(2869577..2870845)	Azoarcus sp. BH72	4610011
YP_934095.1	CDS	azo2591	NC_008702.1	2871202	2873805	D	Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.; hypothetical protein	2871202..2873805	Azoarcus sp. BH72	4607493
YP_934096.1	CDS	azo2592	NC_008702.1	2873818	2874735	D	Conserved hypothetical protein. Homology to Daro03002419 of Dechloromonas aromatica of 51% (gi|41723832|ref|ZP_00150722.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	2873818..2874735	Azoarcus sp. BH72	4607494
YP_934097.1	CDS	azo2593	NC_008702.1	2874754	2876877	D	conserved hypothetical secreted protein. Homology to Daro03002420 of Dechloromonas aromatica of 39% (gi|41723833|ref|ZP_00150723.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2874754..2876877	Azoarcus sp. BH72	4607495
YP_934098.1	CDS	azo2594	NC_008702.1	2876874	2878430	D	Conserved hypothetical membrane protein. Homology to CV2219 of Chromobacterium violaceum of 36% (trembl|Q7NVX2(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	2876874..2878430	Azoarcus sp. BH72	4607496
YP_934099.1	CDS	azo2595	NC_008702.1	2878452	2879951	D	Conserved hypothetical secreted protein. Homology to Daro03002422 of Dechloromonas aromatica of 63% (gi|41723835|ref|ZP_00150725.1|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.; Conserved hypothetical protein; hypothetical protein	2878452..2879951	Azoarcus sp. BH72	4607497
YP_934100.1	CDS	azo2596	NC_008702.1	2879974	2880957	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	2879974..2880957	Azoarcus sp. BH72	4607498
YP_934101.1	CDS	azo2597	NC_008702.1	2880971	2882566	D	Hpyothetical protein with TIR domain. no homology to the data bank. Interpro: TIR domain Pfam: TIR doamin. Site directed mutagenesis and deletion analysis have shown that the TIR domain is essential for Toll and IL-1R activities. Sequence analysis have revealed the presence of three highly conserved regions among the different members of the family: box 1 (FDAFISY), box 2 (GYKLC-RD-PG), and box 3 (a conserved W surrounded by basic residues). It has been proposed that boxes 1 and 2 are involved in the binding of proteins involved in signaling,whereas box 3 is primarily involved in directing localization of receptor, perhaps through interactions with cytoskeletal elements. no signal. peptide 2 TMHs; hypothetical protein	2880971..2882566	Azoarcus sp. BH72	4607499
YP_934102.1	CDS	azo2598	NC_008702.1	2882757	2884553	D	Conserved hypothetical secreted protein. Homology to SMb20495 of S.meliloti of 45% (tremble:Q92W68). Has 3 TPR repeats(IPR001440)(SMART:SM00028):The tetratrico peptide repeat (TPR) is a structural motif present in a wide range of proteins. It mediates protein-protein interactions and the assembly of multiprotein complexes. The TPR motif consists of 3 tandem-repeats of 34 amino acids residues, although individual TPR motifs can be dispersed in the protein sequence. Sequence alignment of the TPR domains reveals a consensus sequence defined by a pattern of small and large amino acids. TPR motifs have been identified in various different organisms, ranging from bacteria to humans. Proteins containing TPRs are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control,mitochondrial and peroxisomal protein transport,neurogenesis and protein folding. No TMH being reported present. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	2882757..2884553	Azoarcus sp. BH72	4607500
YP_934103.1	CDS	abp1	NC_008702.1	2884563	2884940	R	Auxin-binding protein 1 precursor(ABP).This is probably a receptor for the plant hormone auxin. 34% Auxin_BP.IPR007113; Cupin_sup.IPR000886;ER_target_S. Pfam:PF02041; Auxin_BP; 1.; Function unclear; putative auxin-binding protein 1	complement(2884563..2884940)	Azoarcus sp. BH72	4607501
YP_934104.1	CDS	azo2600	NC_008702.1	2885097	2885993	D	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 37% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear; LysR family transcriptional regulator	2885097..2885993	Azoarcus sp. BH72	4608252
YP_934105.1	CDS	azo2601	NC_008702.1	2886006	2886314	R	Ferredoxin subunits of nitrite reductase. THIS SUBUNIT IS A 2FE-2S FERREDOXIN THAT TRANSFERS ELECTRONS TO IRON SULFUR PROTEIN COMPONENTS (ISP). Similar to nasE,from S.aureus_N315 a naphthalene 12-dioxygenase system ferredoxin component.; High confidence in function and specificity; putative ferredoxin subunit of nitrite reductase	complement(2886006..2886314)	Azoarcus sp. BH72	4607502
YP_934106.1	CDS	infA1	NC_008702.1	2886484	2886741	R	Translation initiation factor IF-1. No specific function has so far been attributed to this initiation factor; however it seems to stimulate more or less all the activities of the other two initiation factors IF-2 and IF-3.; Family membership; translation initiation factor IF-1	complement(2886484..2886741)	Azoarcus sp. BH72	4607503
YP_934107.1	CDS	azo2603	NC_008702.1	2886879	2887082	R	Cold shock-like protein,; High confidence in function and specificity; cold shock-like protein	complement(2886879..2887082)	Azoarcus sp. BH72	4609081
YP_934108.1	CDS	azo2604	NC_008702.1	2887497	2888339	D	Conserved hypothetical membrane protein. Homology to ORF62 of Pseudomonas of 60% (trembl|Q936Z8(SRS)). InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter. Pfam: Integral membrane protein DUF6. probable 9 TMHs. signal peptide; Conserved hypothetical protein; hypothetical protein	2887497..2888339	Azoarcus sp. BH72	4607504
YP_934109.1	CDS	azo2605	NC_008702.1	2888355	2888876	R	Conserved hypothetical membrane protein. Homology to cp98 of P. aeruginosa of 33% (tremblnew|AAP22587). no domains predicted. no signal peptide. 2 TMHs.; Conserved hypothetical protein; hypothetical protein	complement(2888355..2888876)	Azoarcus sp. BH72	4607505
YP_934110.1	CDS	azo2606	NC_008702.1	2889090	2889527	D	Conserved hypothetical membrane protein. Homology to gsu0250 of G. sulfurreducens of 46% (tremblnew|AAR33584). no domains predicted. no signal peptide. 3 TMHs.; Conserved hypothetical protein; hypothetical protein	2889090..2889527	Azoarcus sp. BH72	4607506
YP_934111.1	CDS	panE2	NC_008702.1	2889532	2890509	R	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase	complement(2889532..2890509)	Azoarcus sp. BH72	4607507
YP_934112.1	CDS	azo2608	NC_008702.1	2890560	2891330	R	42% Aldolase_II_N.Class II Aldolase and Adducin N-terminal domain. Pfam: PF00596; Aldolase_II; 1. TIGR: PP2871.; High confidence in function and specificity; aldolase II superfamily protein	complement(2890560..2891330)	Azoarcus sp. BH72	4609496
YP_934113.1	CDS	azo2609	NC_008702.1	2891520	2892491	R	Conserved hypothetical endonuclease/exonuclease/phosphatase family protein. Homology to RPBDRAFT_0804 of Rhodopseudomonas palustris HaA2 of 315. Pfam: Exo_endo_phos. Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18 e.g APEX1_HUMAN, DNase I proteins EC:3.1.21.1 e.g. DNAS1_HUMAN, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56 SYNJ1_HUMAN, Sphingomyelinase EC:3.1.4.12 PHL2_BACCE and Nocturnin NOCT_MOUSE. no TMHs. no signal peptide.; Conserved hypothetical protein; endonuclease/exonuclease/phosphatase family protein	complement(2891520..2892491)	Azoarcus sp. BH72	4607508
YP_934114.1	CDS	fhuA2	NC_008702.1	2892605	2894734	R	In E.coli this receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin. Signal peptide.; Specificity unclear; putative ferrichrome-iron TonB-dependent receptor	complement(2892605..2894734)	Azoarcus sp. BH72	4607509
YP_934115.1	CDS	azo2611	NC_008702.1	2894837	2895472	R	Conserved hypothetical membrane protein. Homology to rs00511 of R. solanacearum of 32% (trembl|Q8XUW6(SRS)). No domains predicted. singal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2894837..2895472)	Azoarcus sp. BH72	4608761
YP_934116.1	CDS	azo2612	NC_008702.1	2895707	2896642	R	GAF/GGDEF-domain containing protein,; Conserved hypothetical protein; GAF/GGDEF-domain-containing protein	complement(2895707..2896642)	Azoarcus sp. BH72	4607510
YP_934117.1	CDS	azo2613	NC_008702.1	2896686	2897087	R	Hypothetical protein, 50% identity (59% simialrity)to TrEMBL;Q92TJ5. Has PF04828, Protein of unknown function (DUF636);IPR006913, GFA;This family of proteins has no known function, but several strongly conserved cysteine residues. Glutathione-dependent formaldehyde-activating enzymes catalyze the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione. All known members of this family contain 5 strongly conserved cysteine residues. NO Signal peptide or TMH present.; Function unclear; hypothetical protein	complement(2896686..2897087)	Azoarcus sp. BH72	4607511
YP_934118.1	CDS	azo2614	NC_008702.1	2897216	2897596	R	Conserved hypothetical membrane protein. Homology to Saro02001549 of Novosphingobium aromaticivorans of 37% (gi|48849438|ref|ZP_00303681.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2897216..2897596)	Azoarcus sp. BH72	4607512
YP_934119.1	CDS	azo2615	NC_008702.1	2897663	2898382	R	Hypothetical protein,45% similarity to TrEMBL;Q6LHM7. No Good homology over entire length in the DB. No signal Peptide or TMH present.; Function unclear; hypothetical protein	complement(2897663..2898382)	Azoarcus sp. BH72	4607513
YP_934120.1	CDS	azo2616	NC_008702.1	2898514	2898939	R	Puatative Glyoxalase sub unit, 37% identitcal to TrEMBL;Q89MF5 Has PF00903, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I, catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid . The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyphenylpyruvate dioxygenase. No SIgnal Peptide or TMH reported present.; Family membership; lactoylglutathione lyase	complement(2898514..2898939)	Azoarcus sp. BH72	4607514
YP_934121.1	CDS	azo2617	NC_008702.1	2898954	2899577	R	TREMBL:Q89L44: 48% identity.64% similarity. probable haloacid dehalogenase-like hydrolase. InterPro:IPR005834; Hydrolase. Pfam:PF00702; Hydrolase; Phosphoglycolate phosphatase(PGP). TIGR00099: conserved hypothetical prot; Function unclear; HAD superfamily hydrolase	complement(2898954..2899577)	Azoarcus sp. BH72	4607515
YP_934122.1	CDS	soxR	NC_008702.1	2899574	2900011	R	Probable redox-sensitive transcriptional activator,; High confidence in function and specificity; redox-sensitive transcriptional activator	complement(2899574..2900011)	Azoarcus sp. BH72	4607516
YP_934123.1	CDS	azo2619	NC_008702.1	2900083	2900940	D	Similar to TREMBL:Q98BY2 (39% identity); TREMBL:Q9A2R1 (40% identity); TREMBL:Q89KG6 (34% identity). Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear; putative methyltransferase	2900083..2900940	Azoarcus sp. BH72	4609884
YP_934124.1	CDS	azo2620	NC_008702.1	2900950	2901330	R	Hypothetical membrane protein. no homology to the data bank. no domains predicted signal peptide. 3 TMHs; hypothetical protein	complement(2900950..2901330)	Azoarcus sp. BH72	4607517
YP_934125.1	CDS	azo2621	NC_008702.1	2901512	2902048	R	Conserved hypothetical protein. Homology to VPA0111 of V.parahaemolyticus of 62% (trembl:Q87JY7). Has (IPR010323)PF06041, Bacterial protein of unknown function (DUF924);This family consists of several hypothetical bacterial proteins of unknown function. NO signal peptide or TMH present.; hypothetical protein	complement(2901512..2902048)	Azoarcus sp. BH72	4607518
YP_934126.1	CDS	azo2622	NC_008702.1	2902117	2903265	R	Conserved hypothetical membrane protein,; Conserved hypothetical protein; hypothetical protein	complement(2902117..2903265)	Azoarcus sp. BH72	4607519
YP_934127.1	CDS	azo2623	NC_008702.1	2903667	2904227	R	hypothetical protein	complement(2903667..2904227)	Azoarcus sp. BH72	4607520
YP_934128.1	CDS	azo2624	NC_008702.1	2904323	2904757	D	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.; putative transposase	2904323..2904757	Azoarcus sp. BH72	4607521
YP_934129.1	CDS	azo2625	NC_008702.1	2904840	2904950	D	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 87% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.; putative transposase	2904840..2904950	Azoarcus sp. BH72	4607522
YP_934130.1	CDS	azo2626	NC_008702.1	2904985	2905281	D	Hypothetical truncated transposase. Homology to tnp23 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA2478(KEGG)). No domains predicted. No signal peptide. No TMHs.,; Family membership; putative transposase	2904985..2905281	Azoarcus sp. BH72	4607523
YP_934131.1	CDS	azo2627	NC_008702.1	2905435	2906151	R	Conserved hypothetical protein. Homology to an orf of Polaromanas sp JS666 of 41% No domain predicted. No signal peptide No TMHs; hypothetical protein	complement(2905435..2906151)	Azoarcus sp. BH72	4607524
YP_934132.1	CDS	azo2628	NC_008702.1	2906296	2906745	R	Hypothetical membrane protein. Homology to yptb3870 of Y. pseudotuberculosis of 29% (tremble:Q664A2). No domains predicted. No signal peptide. 1 TMHs; hypothetical protein	complement(2906296..2906745)	Azoarcus sp. BH72	4607525
YP_934133.1	CDS	azo2629	NC_008702.1	2907060	2907413	R	Conserved hypothetical protein. Homology to an orf of Exiguobacterium sp. 255-15 (ZP_00355791). No domains predicted. No signal peptide. 2 TMHs; hypothetical protein	complement(2907060..2907413)	Azoarcus sp. BH72	4607526
YP_934134.1	CDS	cobN	NC_008702.1	2907867	2911886	R	with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN	complement(2907867..2911886)	Azoarcus sp. BH72	4607527
YP_934135.1	CDS	azo2631	NC_008702.1	2911883	2912239	R	Conserved hypothetical membrane protein. Homology to NE0632 of Nitrosomonas europaea of 42% (trembl|Q82WN6(SRS)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(2911883..2912239)	Azoarcus sp. BH72	4607528
YP_934136.1	CDS	azo2632	NC_008702.1	2912250	2912711	R	Conserved hypothetical membrane protein. Homology to PA1924 of P. aeruginosa of 43% (trembl|Q9I2I0(SRS)). No domains predicted. no signal peptide. probable 3TMHS; Conserved hypothetical protein; hypothetical protein	complement(2912250..2912711)	Azoarcus sp. BH72	4607529
YP_934137.1	CDS	tam	NC_008702.1	2913014	2913775	D	Probable trans-aconitate 2-methyltransferase. Homology to tam of E. coli of 48% (sprot|TAM_ECOLI). Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity). Pfam: PTS system, Lactose/Cellobiose specific no signal peptide no TMHs; High confidence in function and specificity; trans-aconitate 2-methyltransferase	2913014..2913775	Azoarcus sp. BH72	4607530
YP_934138.1	CDS	azo2634	NC_008702.1	2913806	2914276	R	Hypothetical membrane protein. no homology to the data bank. no domains predicted. 1 TMHs. no signal peptide; hypothetical protein	complement(2913806..2914276)	Azoarcus sp. BH72	4609914
YP_934139.1	CDS	azo2635	NC_008702.1	2914273	2914899	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2914273..2914899)	Azoarcus sp. BH72	4607531
YP_934140.1	CDS	azo2636	NC_008702.1	2915051	2915770	R	TREMBL:Q7MF75: 35% identity; 50% similarity. IPR006323; Phosphonoacetaldehyde hydrolase IPR010976; Beta-phosphoglucomutase hydrolase This group of sequences represent part of one structural subfamily of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases (IPR005834). The superfamily is defined by the presence of three short catalytic motifs. Hypothetical protein yhcW. InterPro:IPR006402; HAD-SF-IA-v3. IPR005833; Halogease/hydrolase. Pfam: PF00702; Hydrolase Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) IPR005834; Hydrolase. TIGR00099: conserved hypothetical protein; Family membership; putative CbbY family protein	complement(2915051..2915770)	Azoarcus sp. BH72	4607532
YP_934141.1	CDS	azo2637	NC_008702.1	2915888	2916406	R	Conserved hypothetical protein. Homology to RSc0334 of R. solanacearum of 59% (sprot:Y334_RALSO). Pfam: Appr-1-p processing enzyme. No signal peptide. No TMHs.; hypothetical protein	complement(2915888..2916406)	Azoarcus sp. BH72	4607533
YP_934142.1	CDS	azo2638	NC_008702.1	2916466	2918697	R	Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein; ATPase	complement(2916466..2918697)	Azoarcus sp. BH72	4607534
YP_934143.1	CDS	azo2639	NC_008702.1	2918694	2919161	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(2918694..2919161)	Azoarcus sp. BH72	4607535
YP_934144.1	CDS	mdcH	NC_008702.1	2919238	2920236	D	Putative transcriptional factor; putative transcriptional factor	2919238..2920236	Azoarcus sp. BH72	4607536
YP_934145.1	CDS	azo2641	NC_008702.1	2920329	2921015	R	Hypothetical protein. No homology to the data base. No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2920329..2921015)	Azoarcus sp. BH72	4609204
YP_934146.1	CDS	azo2642	NC_008702.1	2921150	2921314	R	Hypothetical protein, very weak homology with any hits in the database. Has , No domains, repeats, motifs or features could be predicted with confidence above threshold scores.; hypothetical protein	complement(2921150..2921314)	Azoarcus sp. BH72	4607537
YP_934147.1	CDS	azo2643	NC_008702.1	2921344	2921907	R	Putative dual specificity protein phosphatase,; Function unclear; putative dual specificity protein phosphatase	complement(2921344..2921907)	Azoarcus sp. BH72	4607538
YP_934148.1	CDS	draG2	NC_008702.1	2922087	2923211	D	Putative ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 24% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs; High confidence in function and specificity; putative ADP-ribosyl-[dinitrogen reductase] hydrolase	2922087..2923211	Azoarcus sp. BH72	4607539
YP_934149.1	CDS	azo2645	NC_008702.1	2923248	2923661	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	2923248..2923661	Azoarcus sp. BH72	4608649
YP_934150.1	CDS	azo2646	NC_008702.1	2923798	2924244	D	Conserved hypothetical protein. Homology to Bucepa03000629 of Burkholderia cepacia of 47% (gi|46324491|ref|ZP_00224852.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	2923798..2924244	Azoarcus sp. BH72	4607540
YP_934151.1	CDS	dlhH	NC_008702.1	2924331	2925149	R	Similar to SWISSPROT:P71505 (50% identity),SWISSPROT:Q8X8L4 (49% identity). Pfam (PF01738): Dienelactone hydrolase family.; High confidence in function and specificity; putative carboxymethylenebutenolidase	complement(2924331..2925149)	Azoarcus sp. BH72	4607541
YP_934152.1	CDS	azo2648	NC_008702.1	2925146	2926453	R	Region start changed from 2926444 to 2926426 (-18 bases); MFS permease	complement(2925146..2926453)	Azoarcus sp. BH72	4608627
YP_934153.1	CDS	azo2649	NC_008702.1	2926624	2928333	R	GGDEF family protein,; Conserved hypothetical protein; diguanylate cyclase	complement(2926624..2928333)	Azoarcus sp. BH72	4607542
YP_934154.1	CDS	azo2650	NC_008702.1	2928487	2928744	R	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide; hypothetical protein	complement(2928487..2928744)	Azoarcus sp. BH72	4607543
YP_934155.1	CDS	azo2651	NC_008702.1	2928823	2929257	R	Conserved hypothetical protein. Homology to ebD23 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebD23(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(2928823..2929257)	Azoarcus sp. BH72	4607544
YP_934156.1	CDS	azo2652	NC_008702.1	2929286	2929984	D	Conserved hypothetical membrane protein. Homology to CC0717 of Caulobacter crescentus of 66% (trembl|Q9AA89(SRS)). Also homology to noduline 21 of G. max of 33% (sprot|NO21_SOYBN(SRS)). Has PF01988,(IPR008217)Integral membrane protein DUF125;This family of predicted integral membrane proteins has no known function. However it does include P47818, that may have a role in regulating calcium levels. no signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	2929286..2929984	Azoarcus sp. BH72	4607545
YP_934157.1	CDS	pitA	NC_008702.1	2930124	2931599	D	Probable low-affinity phosphate transporter protein, PitA. Involved in phosphate transport depending on the proton motive force in E.coli. Similar to Pho-4, a cation-phosphate symporter in N. crassa. InterPro: Phosphate transporter family Signal peptide.; High confidence in function and specificity; putative phosphate transporter	2930124..2931599	Azoarcus sp. BH72	4607546
YP_934158.1	CDS	azo2654	NC_008702.1	2931633	2932103	R	Glyoxalase family protein, 54% identity (67% similarity) to TrEMBL;Q88HB6. Has PF00903,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyphenylpyruvate dioxygenase.; Family membership; lactoylglutathione lyase	complement(2931633..2932103)	Azoarcus sp. BH72	4609583
YP_934159.1	CDS	azo2655	NC_008702.1	2932255	2933628	D	Hypothetical membrane protein. No homology of the entire protein to a protein of similar length. no domains predicted. singal peptie. 6 TMHs; hypothetical protein	2932255..2933628	Azoarcus sp. BH72	4607547
YP_934160.1	CDS	azo2656	NC_008702.1	2933625	2933957	D	Conserved hypothetical membrane protein. Homology to S1719 of Photobacterium profundum of 73% (tremblnew|CAG22368). Has PF02694, Uncharacterized BCR,YnfA/UPF0060 family;IPR003844;This entry describes integral membrane proteins of unknown function. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	2933625..2933957	Azoarcus sp. BH72	4607548
YP_934161.1	CDS	fpr2	NC_008702.1	2934063	2934839	D	Ferredoxin-NADP+ reductase (EC 1.18.1.2) Homology to fpr of A. vinelandii of 75% (sprot|FENR_AZOVI). CATALYTIC ACTIVITY: Reduced ferredoxin + NADP(+) = oxidized ferredoxin + NADPH. Interpro: Oxidoreductase FAD and NAD8P)-binding domain (IPR001433); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidoreductase FAD-binding doamin; Oxidoreductase NAD-binding domain no signal peptide no TMHs; High confidence in function and specificity; ferredoxin-NADP+ reductase	2934063..2934839	Azoarcus sp. BH72	4607549
YP_934162.1	CDS	trxA2	NC_008702.1	2934938	2935267	D	Putative thioredoxin-disulfide reductase. Homology to trxA (ECs4714) of E. coli of 27%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a dislufide. InterPro: Thioredoxin (IPR006662) no TMHs; Family membership; putative thioredoxin-disulfide reductase	2934938..2935267	Azoarcus sp. BH72	4608825
YP_934163.1	CDS	azo2659	NC_008702.1	2935396	2935866	D	Conserved hypothetical secreted protein. Homology to PJS6w01001981 of Polaromonas sp. JS666 of 70% (gi|54030965|ref|ZP_00363100.1|(NBCI ENTREZ)). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2935396..2935866	Azoarcus sp. BH72	4610040
YP_934164.1	CDS	ybcL	NC_008702.1	2935880	2936356	D	Hypothetical protein TC0109. TREMBL:Q8XTTO: 64% identity, 75% similarity. This entry describes a family of conserved hypothetical proteins with no known function. InterPro:IPR005247; Cons_hypoth481. IPR008914; PEBP. Pfam: PF01161; PBP Absence of signal peptide. Absence of TMH's; Function unclear; hypothetical protein	2935880..2936356	Azoarcus sp. BH72	4607550
YP_934165.1	CDS	azo2661	NC_008702.1	2936540	2937082	D	Hypothetical protein which carries at the C-terminus a DnaJ N-terminal domain. InterPro: DnaJ N-terminal domain (IPR001623) Pfam: DnaJ domain no signal peptide no TMHs; hypothetical protein	2936540..2937082	Azoarcus sp. BH72	4610144
YP_934166.1	CDS	azo2662	NC_008702.1	2937338	2938783	D	Conserved hypothetical protein. Homology to ebA2897 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA2897(KEGG)). Has PF01936, Protein of unknown function DUF88;(IPR002790). This highly conserved bacterial protein has no known function. The alignment contains many conserved aspartates, suggesting an enzymatic function such as an endonuclease or glycosyl hydrolase (Bateman A pers. obs). Coils2 Program predcit presence of Coiled Coil. No Signal Peptide or TMH present.; hypothetical protein	2937338..2938783	Azoarcus sp. BH72	4607551
YP_934167.1	CDS	azo2663	NC_008702.1	2938853	2939512	R	Conserve peroxiredoxin. Homology to mll2432 of M. loti of 74% (trembl|Q98IF0). Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic fatty acid and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Pfam: AhpC/TSA family no TMHs. No signal peptide.; Family membership; peroxiredoxin	complement(2938853..2939512)	Azoarcus sp. BH72	4607552
YP_934168.1	CDS	azo2664	NC_008702.1	2939583	2939930	D	Conserved hypothetical protein. Homology to TdenA01001041 of Thiobacillus denitrificans of 39% (gi|52007163|ref|ZP_00334541.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	2939583..2939930	Azoarcus sp. BH72	4607553
YP_934169.1	CDS	azo2665	NC_008702.1	2939940	2940662	R	Hypothetical secreted protein. No homology of the entire protein to the data bank. no domains predicted signal peptide no TMHs; hypothetical protein	complement(2939940..2940662)	Azoarcus sp. BH72	4607554
YP_934170.1	CDS	azo2666	NC_008702.1	2940920	2941666	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Signal peptide present.; hypothetical protein	complement(2940920..2941666)	Azoarcus sp. BH72	4607555
YP_934171.1	CDS	nolR	NC_008702.1	2941903	2942196	D	Putative transcriptional repressor,; High confidence in function and specificity; putative transcriptional repressor	2941903..2942196	Azoarcus sp. BH72	4607556
YP_934172.1	CDS	nerA	NC_008702.1	2942246	2943358	D	Probable glycerol trinitrate reductase. Homology to nerA of A. radiobacter of 66% (trembl|O31246) InterPro: NADH:flavin oxidoreductase/NADH oxidase (IPR001155) Pfam: NADH:flavin oxidoreductase/NADH oxidase no signal peptide no TMHs; High confidence in function and specificity; glycerol trinitrate reductase	2942246..2943358	Azoarcus sp. BH72	4609393
YP_934173.1	CDS	azo2669	NC_008702.1	2943448	2944503	R	Conserved hypothetical cytochrome c family protein. Homology to bra0353 of B. suis of 50% (trembl|Q8FWU2). InterPro: Cytochrome c class I (IPR003088). Pfam: cytochrome c. signal peptide. no TMHS; Function unclear; cytochrome c family protein	complement(2943448..2944503)	Azoarcus sp. BH72	4609353
YP_934174.1	CDS	azo2670	NC_008702.1	2944870	2945280	D	Conserved hypothetical secreted protein. Homology to gsu0710 of G. sulfurreducens of 66% (tremblnew|AAR34040). no doamins predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	2944870..2945280	Azoarcus sp. BH72	4607557
YP_934175.1	CDS	fixJ1	NC_008702.1	2945296	2945943	R	Transcriptional regulatory protein,; Specificity unclear; two-component response regulator	complement(2945296..2945943)	Azoarcus sp. BH72	4607558
YP_934176.1	CDS	azo2672	NC_008702.1	2945927	2947732	R	Conserved hypothetical sensor histidine kinase,MODULATES THE ACTIVITY OF FIXJ A TRANSCRIPTIONAL ACTIVATOR OF NITROGEN FIXATION FIXK GENE. FIXL PROBABLY ACTS AS A KINASE THAT PHOSPHORYLATES FIXJ.; Specificity unclear; putative sensor histidine kinase	complement(2945927..2947732)	Azoarcus sp. BH72	4608766
YP_934177.1	CDS	azo2673	NC_008702.1	2947962	2948441	D	Hypothetical protein,69% Identity (75% similarity) to TrEMBl;Q8XS84 Has PF06983, 3-demethylubiquinone-9 3-methyltransferase;IPR009725 3-dmu-93-mtfrase;This family represents a conserved region approximately 100 residues long within a number of bacterial and archaeal 3-demethylubiquinone-9 3-methyltransferases (EC:2.1.1.64). Note that some family members contain more than one copy of this region, and that many members are hypothetical proteins.; Function unclear; hypothetical protein	2947962..2948441	Azoarcus sp. BH72	4607559
YP_934178.1	CDS	azo2674	NC_008702.1	2949219	2950808	R	Conserved hypothetical membrane protein. Homology to Bcep02002160 of Burkholderia fungorum of 35% (gi|48787369|ref|ZP_00283451.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2949219..2950808)	Azoarcus sp. BH72	4607560
YP_934179.1	CDS	azo2675	NC_008702.1	2950840	2951982	R	catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase	complement(2950840..2951982)	Azoarcus sp. BH72	4607561
YP_934180.1	CDS	azo2676	NC_008702.1	2952049	2952921	R	Similar to TREMBL:Q82SX7 (48% identity, 66% similarity, generic methyl transferase). Pfam (PF01209): ubiE/COQ5 methyltransferase family. TIGRFAM (TIGR00091): conserved hypothetical protein. TMHMM reporting one transmembrane helix.; Function unclear; putative methyltransferase	complement(2952049..2952921)	Azoarcus sp. BH72	4607562
YP_934181.1	CDS	azo2677	NC_008702.1	2952918	2953337	R	Conserved hypothetical membrane protein. Homology to NE2170 of Nitrosomonas europaea of 44% (trembl|Q82SX6(SRS)). Pfam: GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(2952918..2953337)	Azoarcus sp. BH72	4607563
YP_934182.1	CDS	azo2678	NC_008702.1	2953334	2954254	R	hypothetical protein	complement(2953334..2954254)	Azoarcus sp. BH72	4607564
YP_934183.1	CDS	azo2679	NC_008702.1	2954285	2954947	R	InterPro: Bacterial transferase hexapeptide repeat; Function unclear; acyltransferase	complement(2954285..2954947)	Azoarcus sp. BH72	4607565
YP_934184.1	CDS	azo2680	NC_008702.1	2954944	2955885	R	Bactoprenol glucosyl transferase (EC 2.4.1.-). Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity).; Specificity unclear; glycosyltransferase	complement(2954944..2955885)	Azoarcus sp. BH72	4607566
YP_934185.1	CDS	azo2681	NC_008702.1	2955882	2956574	R	High confidence in function and specificity; hypothetical protein	complement(2955882..2956574)	Azoarcus sp. BH72	4607567
YP_934186.1	CDS	azo2682	NC_008702.1	2957374	2957898	D	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	2957374..2957898	Azoarcus sp. BH72	4607568
YP_934187.1	CDS	azo2683	NC_008702.1	2957907	2958251	D	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	2957907..2958251	Azoarcus sp. BH72	4607569
YP_934188.1	CDS	azo2684	NC_008702.1	2958597	2959409	R	putative prophage integrase; Family membership; putative integrase	complement(2958597..2959409)	Azoarcus sp. BH72	4607570
YP_934189.1	CDS	azo2685	NC_008702.1	2960329	2962404	D	GGDEF/EAL/PAS-domain containing protein; diguanylate cyclase	2960329..2962404	Azoarcus sp. BH72	4608238
YP_934190.1	CDS	azo2687	NC_008702.1	2962857	2963009	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide present. TMH in signal peptide.; hypothetical protein	2962857..2963009	Azoarcus sp. BH72	4610021
YP_934191.1	CDS	creA	NC_008702.1	2963024	2963503	R	Putative periplasmic protein [creA],59% identity (77% similarity) to SwissProt;P08367. TrEMBL; Q8XZD0(59% identity). Has PF05981, CreA protein;IPR010292, CreA: This family consists of several bacterial CreA proteins, the function of which is unknown.; High confidence in function and specificity; hypothetical protein	complement(2963024..2963503)	Azoarcus sp. BH72	4607573
YP_934192.1	CDS	azo2689	NC_008702.1	2963500	2963913	R	Conserved hypothetical protein. Homology to Daro03001159 of Dechloromonas aromatica of 50% (gi|41726181|ref|ZP_00152939.1|(NBCI ENTREZ)). Pfam: ProQ activator of osmoprotectant transpoter ProP. This family includes ProQ, which is required for full activation of the osmoprotectant transporter ProQ, in Escherichia coli. no signal. peptide no TMHs; hypothetical protein	complement(2963500..2963913)	Azoarcus sp. BH72	4608529
YP_934193.1	CDS	azo2690	NC_008702.1	2964056	2965018	D	Conserved hypothetical protein. Homology to ebA7139 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA7139(KEGG)). No domains predicted. No signal peptide. No TMH present.; hypothetical protein	2964056..2965018	Azoarcus sp. BH72	4607574
YP_934194.1	CDS	azo2691	NC_008702.1	2965210	2967042	D	GGDEF family protein,; Conserved hypothetical protein; diguanylate cyclase	2965210..2967042	Azoarcus sp. BH72	4607575
YP_934195.1	CDS	azo2692	NC_008702.1	2967068	2968882	D	GGDEF family protein; diguanylate cyclase	2967068..2968882	Azoarcus sp. BH72	4607576
YP_934196.1	CDS	fliC2	NC_008702.1	2969110	2970591	D	Flagellin. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus, Flagellin C-terminus Pfam: Bacterial flagellin N-terminus, bacterial flagellin C-terminus no signal peptide no TMH; High confidence in function and specificity; flagellin	2969110..2970591	Azoarcus sp. BH72	4607577
YP_934197.1	CDS	azo2694	NC_008702.1	2970739	2971869	D	InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; nucleotide sugar aminotransferase	2970739..2971869	Azoarcus sp. BH72	4608796
YP_934198.1	CDS	azo2695	NC_008702.1	2971926	2973140	D	Conserved hypothetical protein. Homology to BF2580 of Bacteroides fragilis of 47% (gnl|keqq|bfr:BF2580(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2971926..2973140	Azoarcus sp. BH72	4607578
YP_934199.1	CDS	azo2696	NC_008702.1	2973203	2974009	D	Conserved hypothetical protein. Homology to Mmc102000919 of Magnetococcus sp. MC-1 of 48% (gi|48833619|ref|ZP_00290637.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	2973203..2974009	Azoarcus sp. BH72	4607579
YP_934200.1	CDS	azo2697	NC_008702.1	2974127	2975602	D	Hypothetical protein. No homology of the entire protein with the data base. InterPro: Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids. No signal peptide. No TMHs; hypothetical protein	2974127..2975602	Azoarcus sp. BH72	4607580
YP_934201.1	CDS	pepM	NC_008702.1	2975648	2976952	D	Phosphoenolpyruvate phosphomutase precursor(Phosphoenolpyruvate mutase) (PEP mutase) (PEP phosphomutase).FORMATION OF A CARBON-PHOSPHORUS BOND BY CONVERTING PHOSPHOENOLPYRUVATE (PEP) TO PHOSPHONOPYRUVATE (P-PYR). 34% Isocit_lyase_ph.; High confidence in function and specificity; putative phosphoenolpyruvate phosphomutase	2975648..2976952	Azoarcus sp. BH72	4607581
YP_934202.1	CDS	azo2699	NC_008702.1	2976949	2978073	D	3-phosphonopyruvate decarboxylase (EC 4.1.1.-). InterPro: Thiamine pyrophosphate dependent enzyme acolac_lg: acetolactate synthase large subunit,biosynthetic type; Family membership; phosphonopyruvate decarboxylase	2976949..2978073	Azoarcus sp. BH72	4609521
YP_934203.1	CDS	azo2700	NC_008702.1	2978078	2979187	D	Conserved hypothetical alcohol dehydrogenase. Homology to bp2820 of B. pertussis of 29% (TREMBL:Q7VV69). InterPro: Iron-containing alcohol dehydrogenase (IPR001670). Pfam: Iron-containing alcohol dehydrogenase. no signal peptide. no TMHs.; Family membership; alcohol dehydrogenase	2978078..2979187	Azoarcus sp. BH72	4607582
YP_934204.1	CDS	azo2701	NC_008702.1	2979203	2980453	D	Putative CDP-glycerol:glycerophosphate glycerophosphotransferase tarF (EC 2.7.8.-). Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked dissacharide to complete the linkage unit (Potential). PurN: phosphoribosylglycinamide formy; Family membership; teichoic acid biosynthesis protein B	2979203..2980453	Azoarcus sp. BH72	4607583
YP_934205.1	CDS	azo2702	NC_008702.1	2980491	2984042	D	InterPro: Glycosyl transferase family 2; Family membership; glycosyltransferase	2980491..2984042	Azoarcus sp. BH72	4607584
YP_934206.1	CDS	azo2703	NC_008702.1	2984043	2986367	R	Conserved hypothetical protein. Homology to magn028431 of M. magnetotacticum of 33% (ZP 00053827). Domain structur: 76 aa - 144 aa TPR; 201 aa - 316 aa TPR; 408 aa - 761 aa COG3914. InterPro: TPR repeat (IPR001440). no signal peptide no TMH.; hypothetical protein	complement(2984043..2986367)	Azoarcus sp. BH72	4607585
YP_934207.1	CDS	fliC3	NC_008702.1	2986580	2988061	D	Flagellin. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. InterPro: Flagellin N-terminus, Flagellin C-terminus Pfam: Bacterial flagellin N-terminus, bacterial flagellin C-terminus no TMH no signal peptide; High confidence in function and specificity; flagellin	2986580..2988061	Azoarcus sp. BH72	4607586
YP_934208.1	CDS	flaG	NC_008702.1	2988140	2988544	D	Protein flaG. Although these proteins are known to be important for flagellar their exact function is unknown TREMBL:Q82UA2: 56% identity, 79% similarity. InterPro:IPR005186; FlaG. Pfam:PF03646; FlaG L12: ribosomal protein L7/L12 Nonsecretory protein with low signal peptide probability (0.041): SignalP predicted Transmembrane helices 0; High confidence in function and specificity; flagellar protein	2988140..2988544	Azoarcus sp. BH72	4608797
YP_934209.1	CDS	fliD	NC_008702.1	2988571	2989992	D	Flagellar hook-associated protein 2 (HAP2) (Filament cap protein) (Flagellar cap protein). The flagellar hook-associated protein 2 (AHP2 or FilD) is a capping protein for the flagella and forms the distal end of the flagella. The protein plays a role in mucin specific adhesion of the bacteria. InterPro: Flagellar hook-associated protein 2 no signal-peptide no TMHs; High confidence in function and specificity; flagellar hook-associated protein	2988571..2989992	Azoarcus sp. BH72	4608769
YP_934210.1	CDS	fliS	NC_008702.1	2990004	2990414	D	Flagellar protein fliS. The function of this protein in flagellar biosynthesis is unknown, but appears to be regulatory. Might be a chaperon for Flic. InterPro: Flagellar protein FliS fliS: flagellar protein FliS Pfam: Flagellar protein FliS no signal peptide no TMHs; Family membership; flagellar protein FliS	2990004..2990414	Azoarcus sp. BH72	4608798
YP_934211.1	CDS	fliT	NC_008702.1	2990427	2990744	D	Hypothetical lagellar related protein FliT. Homology to fliT of R. solanacearum of 27% (trembl|Q8XST2). no domains predicted. no signal peptide. no TMHs.; flagellar-like protein FliT	2990427..2990744	Azoarcus sp. BH72	4608812
YP_934212.1	CDS	azo2709	NC_008702.1	2990776	2991891	D	Hypothetical protein,42% similarity with TrEMBL;Q82T52. No Signal Peptide or TMH reported present.; Family membership; hypothetical protein	2990776..2991891	Azoarcus sp. BH72	4608813
YP_934213.1	CDS	azo2710	NC_008702.1	2991881	2992258	D	Conserved hypothetical flagellar related protein. Homology to NE2078 of Nitrosomonas europaea of 48% (CAD85989). Tirgfam: flhB_rel(TIGR). This group describes a short protein (80-93 residues) homologous to the C-terminus of the flagellar biosynthetic protein FlhB. It is found so far only in species that also have FlhB. In a phylogenetic tree based on alignment of both this family and the homologous region of FlhB and its homologs, the members of this family form a monophyletic set. No TMHs. No signal peptide.; Conserved hypothetical protein; flagellar related protein	2991881..2992258	Azoarcus sp. BH72	4607587
YP_934214.1	CDS	azo2711	NC_008702.1	2992357	2993136	D	Conserved hypothetical protein,55% similarity to TrEMBL;Q82T50. Has IPR009926;PF07317:YcgR protein;This family consists of several hypothetical YcgR proteins. YcgR may be involved in the flagellar motor function and may be a new member of the flagellar regulon. No signal peptide or TMH reported present.; Function unclear; hypothetical protein	2992357..2993136	Azoarcus sp. BH72	4607588
YP_934215.1	CDS	azo2712	NC_008702.1	2993380	2997147	D	GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein; diguanylate cyclase	2993380..2997147	Azoarcus sp. BH72	4607589
YP_934216.1	CDS	azo2713	NC_008702.1	2997226	2997522	R	Region start changed from 2997519 to 2997495 (-24 bases); flagellar hook-basal body complex protein FliE	complement(2997226..2997522)	Azoarcus sp. BH72	4607590
YP_934217.1	CDS	fleR	NC_008702.1	2997698	2999176	R	Sigma-54 dependent response regulator,; High confidence in function and specificity; sigma-54 dependent response regulator	complement(2997698..2999176)	Azoarcus sp. BH72	4607591
YP_934218.1	CDS	fleS	NC_008702.1	2999173	3000354	R	Putative sensory box sensor histidine kinase,; High confidence in function and specificity; putative sensory box sensor histidine kinase	complement(2999173..3000354)	Azoarcus sp. BH72	4608774
YP_934219.1	CDS	fliF	NC_008702.1	3000514	3002202	D	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein	3000514..3002202	Azoarcus sp. BH72	4608775
YP_934220.1	CDS	fliG	NC_008702.1	3002199	3003197	D	Flagellar motor switch protein fliG. FLIG IS ONE OF THREE PROTEINS (FLIG FLIN FLIM) THAT FORM A SWITCH COMPLEX THAT IS PROPOSED TO BE LOCATED AT THE BASE OF THE BASAL BODY. THIS COMPLEX INTERACTS WITH THE CHEY AND CHEZ CHEMOTAXIS PROTEINS IN ADDITION TO CONTACTING COMPONENTS OF THE MOTOR THAT DETERMINE THE DIRECTION OF FLAGELLAR ROTATION (BY SIMILARITY). fliG: flagellar motor switch protein Pfam: fliG C-terminal domain no signal peptide no TMHs; High confidence in function and specificity; flagellar motor switch protein FliG	3002199..3003197	Azoarcus sp. BH72	4608799
YP_934221.1	CDS	fliH	NC_008702.1	3003231	3003977	D	Probable Flagellar assembly protein FliH, 38% identity to TrEMBL;Q7VYE7, Q7WJB3, Q8XSS5. Has PF02108,Flagellar assembly protein FliH;IPR000563, Flag_FliH; Many flagellar proteins are exported by a flagellum-specific export pathway. Attempts have been made to characterise the apparatus responsible for this process, by designing assays to screen for mutants with export defects. Experiments involving filament removal from temperature-sensitive flagellar mutants of Salmonella typhimurium have shown that, while most mutants were able to regrow filaments, flhA, fliH, fliI and fliN mutants showed no or greatly reduced regrowth. This suggests that the corresponding gene products are involved in the process of flagellum-specific export. The sequence of fliH has been deduced and shown to encode a protein of molecular mass of 25,782 Da.; flagellar assembly protein FliH	3003231..3003977	Azoarcus sp. BH72	4608800
YP_934222.1	CDS	fliI	NC_008702.1	3003991	3005397	D	ATP synthase (EC 3.6.3.14). Probable catalytic subunit of a protein translocase for flagellum-specific export or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage. InterPro: ATP synthase alpha and beta subunit central region Pfam: ATP synthase alpha/beta family no signal peptide no TMHs; High confidence in function and specificity; ATP synthase	3003991..3005397	Azoarcus sp. BH72	4608801
YP_934223.1	CDS	fliJ	NC_008702.1	3005493	3005945	D	Flagellar fliJ protein. FLAGELLAR PROTEIN THAT AFFECTS CHEMOTACTIC EVENTS. Might have a chaperon-like activity InterPro: Flagellar FliJ protein no signal peptide no TMHs; Family membership; putative flagellar protein FliJ	3005493..3005945	Azoarcus sp. BH72	4608802
YP_934224.1	CDS	fliK	NC_008702.1	3006109	3007209	D	Flagellar hook-length control protein. Controls the length of the flagellar hook. no TMHs no signal peptide; Family membership; putative flagellar hook-length control protein FliK	3006109..3007209	Azoarcus sp. BH72	4608803
YP_934225.1	CDS	fliL	NC_008702.1	3007300	3007881	D	putative flagellar basal body-associated protein FliL Controls the rotational direction of flagella during chemotaxis. no signal peptide no TMHs; Family membership; putative flagellar basal body-associated protein FliL	3007300..3007881	Azoarcus sp. BH72	4608804
YP_934226.1	CDS	fliM	NC_008702.1	3007896	3008906	D	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM	3007896..3008906	Azoarcus sp. BH72	4608805
YP_934227.1	CDS	fliN	NC_008702.1	3008899	3009378	D	Flagellar motor switch protein fliN (Flagellar motor switch protein mopA) (Fragment). FliN is one of three proteins (FliG FliN FliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins in addition to contacting components of the motor that determine the dirction of flagellar rotation (by similarity). InterPro: Surface presentation of antigens (SPOA) protein, Flagellar motor switch FliN protein Pfam: Surface presentation of antigens (SPOA) protein no signal peptide no TMHs; High confidence in function and specificity; flagellar motor switch FliN	3008899..3009378	Azoarcus sp. BH72	4608806
YP_934228.1	CDS	fliO	NC_008702.1	3009540	3009863	D	Flagellar biosynthesis protein,FliO, 26% identity to TrEMBL;Q8XBA2, Q83ML3. SProt;P22586 Has Signal peptide. Has PF04347, Flagellar biosynthesis protein,FliO;IPR007442 ; FliO is an essential component of the flagellum-specific protein export apparatus. It is an integral membrane protein. Its precise molecular function is unknown.; flagellar biosynthesis protein FliO	3009540..3009863	Azoarcus sp. BH72	4608807
YP_934229.1	CDS	fliP	NC_008702.1	3009853	3010629	D	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP	3009853..3010629	Azoarcus sp. BH72	4608808
YP_934230.1	CDS	fliQ	NC_008702.1	3010643	3010912	D	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ	3010643..3010912	Azoarcus sp. BH72	4608809
YP_934231.1	CDS	fliR	NC_008702.1	3010935	3011747	D	Flagellar biosynthesis protein fliR. Role in flagellar biosynthesis. InterPro: Bacterial export protein family 1 PFam: Bacterial export proteins, family 1 no signal peptide most probable 8 TMHs; High confidence in function and specificity; flagellar biosynthesis protein FliR	3010935..3011747	Azoarcus sp. BH72	4608810
YP_934232.1	CDS	azo2729	NC_008702.1	3011751	3012236	R	Hypothetical secreted protein. no homology to the data bank. no domains predicted signal peptide no TMHs; hypothetical protein	complement(3011751..3012236)	Azoarcus sp. BH72	4608811
YP_934233.1	CDS	flgL	NC_008702.1	3012247	3013509	R	Flagellar hook-associated protein 3 (HAP3) (Hook-filament junction protein). no signal peptide no TMHs; High confidence in function and specificity; flagellar hook-filament junction protein 3	complement(3012247..3013509)	Azoarcus sp. BH72	4607592
YP_934234.1	CDS	flgK	NC_008702.1	3013521	3015512	R	flagellar hook-filament junction protein 1 (HAP1). no signal peptide no TMHs; High confidence in function and specificity; flagellar hook-filament junction protein 1	complement(3013521..3015512)	Azoarcus sp. BH72	4608787
YP_934235.1	CDS	flgJ	NC_008702.1	3015668	3016735	R	Peptidoglycan hydrolase flgJ (EC 3.2.1.-) (Muramidase flgJ). Flagellum-specific muramidase which hydrolyses the peptidoglycan layer to assemble the rod structure in the periplasmic space (by similarity). InterPro: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidases Pfam: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidases no signal peptide no TMHs; High confidence in function and specificity; peptidoglycan hydrolase	complement(3015668..3016735)	Azoarcus sp. BH72	4608786
YP_934236.1	CDS	flgI	NC_008702.1	3016818	3017930	R	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein	complement(3016818..3017930)	Azoarcus sp. BH72	4608785
YP_934237.1	CDS	flgH	NC_008702.1	3017950	3018627	R	Flagellar L-ring protein precursor (Basal body L-ring protein). Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. The L ring reside in the outer membrane. FlgH, which is exported across the cell membrane to their destinations in the outer membrane, has a typical N-terminal cleaved signal-peptide sequences and is predicted to have an extensive -sheet structure, in keeping with other outer membrane proteins. Pfam: Flagellar L-ring protein signal peptide no TMHs; High confidence in function and specificity; flagellar L-ring protein	complement(3017950..3018627)	Azoarcus sp. BH72	4608784
YP_934238.1	CDS	flgG	NC_008702.1	3018650	3019432	R	makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG	complement(3018650..3019432)	Azoarcus sp. BH72	4608783
YP_934239.1	CDS	flgF	NC_008702.1	3019571	3020308	R	Flagellar basal-body rod protein flgF (Putative proximal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity; flagellar basal-body rod protein FlgF	complement(3019571..3020308)	Azoarcus sp. BH72	4608782
YP_934240.1	CDS	flgE	NC_008702.1	3020334	3021671	R	Flagellar hook protein flgE. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity; FlgE protein	complement(3020334..3021671)	Azoarcus sp. BH72	4608781
YP_934241.1	CDS	flgD	NC_008702.1	3021687	3022361	R	Basal-body rod modification protein flgD. FlgD is known to be absolutely required for hook assembly, yet it has not been detected in the mature flagellum. It appears to act as a hook-capping protein to enable assembly of hook protein subunits. no signal peptide no TMHs; Family membership; basal-body rod modification protein FlgD	complement(3021687..3022361)	Azoarcus sp. BH72	4608780
YP_934242.1	CDS	flgC	NC_008702.1	3022403	3022843	R	Flagellar basal-body rod protein flgC. The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity; flagellar basal-body rod protein FlgC	complement(3022403..3022843)	Azoarcus sp. BH72	4608779
YP_934243.1	CDS	flgB	NC_008702.1	3022865	3023266	R	Flagellar basal-body rod protein flgB (Putative proximal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. no signal peptide no TMHs; High confidence in function and specificity; flagellar basal-body rod protein FlgB	complement(3022865..3023266)	Azoarcus sp. BH72	4608778
YP_934244.1	CDS	flgA	NC_008702.1	3023519	3024289	D	Flagella basal body P-ring formation protein flgA precursor. Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a chaperon protein for the P-ring assembly (by similarity). signal peptide no TMHs; High confidence in function and specificity; chaperon for flagellar basal body P-ring formation	3023519..3024289	Azoarcus sp. BH72	4608777
YP_934245.1	CDS	azo2742	NC_008702.1	3024385	3024681	D	Region start changed from 3024385 to 3024358 (27 bases); putative negative regulator of flagellin synthesis FlgM	3024385..3024681	Azoarcus sp. BH72	4608776
YP_934246.1	CDS	flgN	NC_008702.1	3024695	3025174	D	Putative chaperon of flagella synthesis. FlgN is an export chaperon of FlgM and FlgK involved in flagellar synthesis. no signal peptide no TMHs; Family membership; putative flagellar synthesis chaperone	3024695..3025174	Azoarcus sp. BH72	4607593
YP_934247.1	CDS	azo2744	NC_008702.1	3025253	3025792	R	Hypothetical secreted protein. Homology to cv0285 of C. violaceum of 25% (trembl|Q7P1C8) no domains predicted signal peptide TMH in signal peptide; hypothetical protein	complement(3025253..3025792)	Azoarcus sp. BH72	4608788
YP_934248.1	CDS	ompR2	NC_008702.1	3025977	3026735	D	Probable DNA-binding response regulator, ITS CARBOXYL-TERMINAL MOIETY MEDIATES THE MULTIMERIZATION OF THE OMPR PROTEIN. AS A MULTIMER IT TURNS ON THE EXPRESSION OF THE OMPC GENE; AS A MONOMER IT TURNS ON THE EXPRESSION OF THE OMPF GENE.; High confidence in function and specificity; DNA-binding response regulator	3025977..3026735	Azoarcus sp. BH72	4607594
YP_934249.1	CDS	envZ2	NC_008702.1	3026732	3028066	D	Putative sensor histidine kinase,; High confidence in function and specificity; putative sensor histidine kinase	3026732..3028066	Azoarcus sp. BH72	4609447
YP_934250.1	CDS	azo2747	NC_008702.1	3028173	3028706	R	Conserved hypothetical protein. Homology to ebA6852 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA6852(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(3028173..3028706)	Azoarcus sp. BH72	4608672
YP_934251.1	CDS	azo2748	NC_008702.1	3029233	3031296	D	Putative sensory box histidine kinase, very low similarity to TREMBL: trembl|Q9FD00 (12% Erwinia stewartii, HrpX) InterPro: IPR005467 His_kinase. IPR003661 His_kinA_N. IPR000014 PAS_domain. IPR001610 PAC Pfam: PF02518 HATPase_c. PF00989 PAS. PF00785 PAC. TIGRFAM:TIGR00229 PAS domain S-box.; Function unclear; putative sensory box histidine kinase	3029233..3031296	Azoarcus sp. BH72	4607595
YP_934252.1	CDS	vsrD2	NC_008702.1	3031290	3031919	D	Probable transcriptional regulator, LuxR family,; Specificity unclear; LuxR family transcriptional regulator	3031290..3031919	Azoarcus sp. BH72	4607596
YP_934253.1	CDS	glpA	NC_008702.1	3031885	3033474	R	Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership; putative glycerol-3-phosphate dehydrogenase	complement(3031885..3033474)	Azoarcus sp. BH72	4610099
YP_934254.1	CDS	glpK	NC_008702.1	3033471	3034961	R	Probable glycerol kinase. Homology to glpK of T. aquaticus of 53% (sprot|GLPK_THEAQ). Key enzyme in the regulation of glycerol uptake and metabolism. InterPro: Carbohydrate kinase FGGY family (IPR000577) Pfam: FGGY family of carobhydrates kinases, N-terminus; FGGY family of carobhydrates kinases, C-terminus no signal peptide no TMHs; High confidence in function and specificity; glycerol kinase	complement(3033471..3034961)	Azoarcus sp. BH72	4608911
YP_934255.1	CDS	azo2752	NC_008702.1	3035084	3035953	D	Conserved hypothetical membrane protein. Homology with CV1535 of C. violaceum of 46%. 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Intergral membrane protein DUF6. probable 9 TMHs. signal peptide; Conserved hypothetical protein; hypothetical protein	3035084..3035953	Azoarcus sp. BH72	4608912
YP_934256.1	CDS	azo2753	NC_008702.1	3036044	3036406	D	Conserved hypothetical protein. Homology to NE1501 of N.europaea of 47% (trembl:Q82UI4). No domains predicted. Signal peptide present. No TMH reported present.; hypothetical protein	3036044..3036406	Azoarcus sp. BH72	4607597
YP_934257.1	CDS	sseA	NC_008702.1	3036403	3037257	D	SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity; putative thiosulfate sulfurtransferase	3036403..3037257	Azoarcus sp. BH72	4607598
YP_934258.1	CDS	murI	NC_008702.1	3037292	3038107	R	converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase	complement(3037292..3038107)	Azoarcus sp. BH72	4609893
YP_934259.1	CDS	azo2756	NC_008702.1	3038104	3039303	R	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase	complement(3038104..3039303)	Azoarcus sp. BH72	4609294
YP_934260.1	CDS	azo2757	NC_008702.1	3039381	3040709	D	Hypothetical metalloprotease yebA precursor (EC 3.4.24.-).; Specificity unclear; metalloprotease	3039381..3040709	Azoarcus sp. BH72	4607599
YP_934261.1	CDS	azo2758	NC_008702.1	3040778	3041128	R	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA	complement(3040778..3041128)	Azoarcus sp. BH72	4607600
YP_934262.1	CDS	rpsI	NC_008702.1	3041369	3041761	R	forms a direct contact with the tRNA during translation; 30S ribosomal protein S9	complement(3041369..3041761)	Azoarcus sp. BH72	4607601
YP_934263.1	CDS	rplM	NC_008702.1	3041775	3042203	R	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13	complement(3041775..3042203)	Azoarcus sp. BH72	4609812
YP_934264.1	CDS	azo2761	NC_008702.1	3042732	3043124	D	Conserved hypothetical protein. Homology to rsc0489 of R. solanacearum of 73% (trembl|Q8Y247). no signal peptide. no TMH. No domains predicted.; Family membership; hypothetical protein	3042732..3043124	Azoarcus sp. BH72	4609772
YP_934265.1	CDS	azo2762	NC_008702.1	3043258	3043878	R	Probable Ubiquinone biosynthesis protein COQ7 homolog (Coenzyme Q biosynthesis protein 7 homolog) (Timing protein clk-1 homolog) (Fragment).; Function unclear; ubiquinone biosynthesis protein	complement(3043258..3043878)	Azoarcus sp. BH72	4607602
YP_934266.1	CDS	azo2763	NC_008702.1	3043881	3044411	R	Conserved hypothetical secreted protein. Homology to ebA945 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA945(KEGG)). No domains predicted. Signal P reporting signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3043881..3044411)	Azoarcus sp. BH72	4607603
YP_934267.1	CDS	azo2764	NC_008702.1	3044471	3044998	R	hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase	complement(3044471..3044998)	Azoarcus sp. BH72	4607604
YP_934268.1	CDS	azo2765	NC_008702.1	3045152	3046897	D	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase	3045152..3046897	Azoarcus sp. BH72	4607605
YP_934269.1	CDS	azo2766	NC_008702.1	3046921	3047592	D	Probable Membrane-bound lytic murein transglycosylase C precursor (EC 3.2.1.-) (Murein hydrolase C).; Function unclear; soluble lytic murein transglycosylase	3046921..3047592	Azoarcus sp. BH72	4607606
YP_934270.1	CDS	azo2767	NC_008702.1	3047582	3048178	R	Conserved hypothetical protein. Homology to Daro03000304 of Dechloromonas aromatica of 54% (gi|46140561|ref|ZP_00152132.2|(NBCI ENTREZ)). Has PF04519; Protein of unknown function, DUF583:This family contains several uncharacterised hypothetical proteins. No Signal peptide or TMH reported as present.; hypothetical protein	complement(3047582..3048178)	Azoarcus sp. BH72	4607607
YP_934271.1	CDS	yfhK	NC_008702.1	3048521	3049915	D	Putative two-component system sensor kinase,; Family membership; putative two-component system sensor kinase	3048521..3049915	Azoarcus sp. BH72	4607608
YP_934272.1	CDS	azo2769	NC_008702.1	3049908	3050480	D	Conserved hypothetical secreted protein. Homology to ebA964 of Azoarcus sp. EbN1 of 33% (gnl|keqq|eba:ebA964(KEGG)). No domains predicted. Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	3049908..3050480	Azoarcus sp. BH72	4610174
YP_934273.1	CDS	yfhA	NC_008702.1	3050477	3051874	D	Putative two component transcriptional regulator,; Conserved hypothetical protein; putative two component transcriptional regulator	3050477..3051874	Azoarcus sp. BH72	4607609
YP_934274.1	CDS	azo2771	NC_008702.1	3051907	3053010	D	hypothetical protein	3051907..3053010	Azoarcus sp. BH72	4610172
YP_934275.1	CDS	mnmA	NC_008702.1	3053030	3054127	R	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA	complement(3053030..3054127)	Azoarcus sp. BH72	4607610
YP_934276.1	CDS	azo2773	NC_008702.1	3054144	3054806	R	Conserved hypothetical secreted protein. Homology to ebA988 of Azoarcus sp. EbN1 of 43% (gnl|keqq|eba:ebA988(KEGG)). no domains predicted. signal peptie. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(3054144..3054806)	Azoarcus sp. BH72	4607611
YP_934277.1	CDS	azo2774	NC_008702.1	3054806	3055288	R	Putative Nudix hydrolase ymfB (EC 3.6.-.-). mutt: mutator mutT protein; Specificity unclear; hypothetical protein	complement(3054806..3055288)	Azoarcus sp. BH72	4607612
YP_934278.1	CDS	ilvE2	NC_008702.1	3055412	3056332	D	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase	3055412..3056332	Azoarcus sp. BH72	4607613
YP_934279.1	CDS	azo2776	NC_008702.1	3056343	3056543	D	Hypothetical protein , 47% identity to TrEMBL;Q7NW97,TrEMBL;Q7VTV4(56% identity). No domains,repeats, motifs or features present.; Function unclear; hypothetical protein	3056343..3056543	Azoarcus sp. BH72	4609073
YP_934280.1	CDS	azo2777	NC_008702.1	3056655	3057674	D	Conserved hypothetical protein. Homology to ne1289 of N. europaea of 49% (trembl|Q82V21). InterPro: Esterase/lipase/thioesterase family active site (IPR000379). no signal peptide. no TMH.; hypothetical protein	3056655..3057674	Azoarcus sp. BH72	4607614
YP_934281.1	CDS	pgm	NC_008702.1	3057734	3059125	D	Phosphomannomutase/phosphoglucomutase (PMM / PGM). The phosphomannomutase activity produces a precursor for alginate polymerization. This enzyme participates in both the breakdown and synthesis of glucose.Catalytic activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 58% PG/PMM_mutase.IPR005844; PG_PMM_ABAI.IPR005845; PG_PMM_ABAII.IPR005846; PG_PMM_ABAIII.IPR005843; PG_PMM_C. Pfam:PF02878; PGM_PMM_I; 1.PF02879; PGM_PMM_II; 1.PF02880; PGM_PMM_III. PF00408; PGM_PMM_IV; 1.; High confidence in function and specificity; putative phosphoglucomutase	3057734..3059125	Azoarcus sp. BH72	4607615
YP_934282.1	CDS	azo2779	NC_008702.1	3059222	3060082	D	Conserved hypothetical protein with unknown function. No domains predicted. Similarity to TREMBL: trembl|Q9I6D7 (33% Pseudomonas aeruginosa, hypothetical protein pa0356) / trembl|Q88CQ4 (30% Pseudomonas putida (strain KT2440), pp5126); hypothetical protein	3059222..3060082	Azoarcus sp. BH72	4609532
YP_934283.1	CDS	alaS	NC_008702.1	3060174	3062831	R	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase	complement(3060174..3062831)	Azoarcus sp. BH72	4607616
YP_934284.1	CDS	azo2781	NC_008702.1	3062977	3063528	D	Conserved hypothetical protein. Homology to ebA1022 of Azoarcus sp. EbN1 of 86% (gnl|keqq|eba:ebA1022(KEGG)). Has PF01923, Cobalamin adenosyltransferase;IPR002779,DUF80; This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation. The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12. No signal peptide or TMH present.; hypothetical protein	3062977..3063528	Azoarcus sp. BH72	4608291
YP_934285.1	CDS	azo2782	NC_008702.1	3063558	3063926	R	Conserved hypothetical protein. Homology to am orf of Azotobacter vinelandii of 51% (gi|67087339|gb|EAM06806.1). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B,Y and X) proteins which are iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide. No TMHs.; hypothetical protein	complement(3063558..3063926)	Azoarcus sp. BH72	4607617
YP_934286.1	CDS	azo2783	NC_008702.1	3063993	3064577	D	Probable RNA-directed RNA polymerase (EC 2.7.7.48) (RNA replicase) (216.5 kDa protein) (ORF1). alkb: alkylated DNA repair protein AlkB.; Function unclear; DNA repair system specific for alkylated DNA	3063993..3064577	Azoarcus sp. BH72	4607618
YP_934287.1	CDS	azo2784	NC_008702.1	3064764	3065855	D	Conserved hypothetical monoamine oxidase. Homology to rsp0431 of R. solanacearum of 34% (trembl|Q8XSN6). In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. InterPro: Amine oxidase (IPR002937). Pfam: Flavin containing amine oxidase. probable signal peptide. no TMH.; Family membership; monoamine oxidase	3064764..3065855	Azoarcus sp. BH72	4607619
YP_934288.1	CDS	azo2785	NC_008702.1	3065910	3067784	R	Conserved hypothetical membrane protein. Homology to SC3D11.05C of Streptomyces coelicolor of 33% (trembl|Q9L1F7(SRS)). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting three transmembrane helices. No signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(3065910..3067784)	Azoarcus sp. BH72	4607620
YP_934289.1	CDS	dinP	NC_008702.1	3067852	3068925	R	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV	complement(3067852..3068925)	Azoarcus sp. BH72	4607621
YP_934290.1	CDS	rumC	NC_008702.1	3068980	3070395	R	Conserved hypothetical RumC homolog. Homology to rumC of P.aeruginosa of 43% (gi|20139744|sp|Q9I4U3|RMUC_PSEAE). Pfam: RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures. Signal peptide predicted. 2 TMHs.,; Conserved hypothetical protein; putative RumC-like protein	complement(3068980..3070395)	Azoarcus sp. BH72	4608621
YP_934291.1	CDS	aroG	NC_008702.1	3070509	3071594	R	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase	complement(3070509..3071594)	Azoarcus sp. BH72	4609834
YP_934292.1	CDS	kefC	NC_008702.1	3071733	3072989	D	Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter). Transport system that facilitates potassium-efflux possibly by potassium-proton antiport.Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily. 23% K_eff.IPR006153; Na_H_porter. Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:11; High confidence in function and specificity; putative cation/proton antiporter	3071733..3072989	Azoarcus sp. BH72	4608347
YP_934293.1	CDS	azo2790	NC_008702.1	3073104	3074060	D	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY	3073104..3074060	Azoarcus sp. BH72	4609106
YP_934294.1	CDS	azo2791	NC_008702.1	3074075	3074752	D	Conserved hypothetical membrane protein. Homology to cv0790 of C. violaceum of 50% (tremble:Q7NZX9). Has PF05252, Uncharacterised protein family (UPF0191);IPR007916 ; This family of proteins is functionally uncharacterised. signal peptide. 5 TMHs; Conserved hypothetical protein; hypothetical protein	3074075..3074752	Azoarcus sp. BH72	4607622
YP_934295.1	CDS	mogA	NC_008702.1	3074783	3075376	R	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA	complement(3074783..3075376)	Azoarcus sp. BH72	4607623
YP_934296.1	CDS	yjgA	NC_008702.1	3075373	3075936	R	Hypothetical protein yjgA, 46% identity(59% similarity) to SwissProt;Q8FAF3.SwissProt;Q83P53 Has PF04751, Protein of unknown function (DUF615);IPR006839;This family of bacterial proteins has no known function. NO Signal Peptide or TMH reported present.; Function unclear; hypothetical protein	complement(3075373..3075936)	Azoarcus sp. BH72	4609259
YP_934297.1	CDS	pmbA	NC_008702.1	3076001	3077341	D	Probable PmbA protein. Homology to pmbA of E. coli of 48% (sprot|PMBA_ECOLI). MAY FACILITATE THE SECRETION OF THE PEPTIDE ANTIBIOTIC MICROCIN B17 (MCCB17) BY COMPLETING ITS MATURATION. SUPPRESSES THE INHIBITORY ACTIVITY OF THE CARBON STORAGE REGULATOR (CSRA). Pfam: Putative modulator of DNA gyrase no signal peptide no TMHs; High confidence in function and specificity; PmbA protein	3076001..3077341	Azoarcus sp. BH72	4610189
YP_934298.1	CDS	azo2795	NC_008702.1	3077588	3078736	D	Similar to TREMBL:Q8G2H7 (58% identity); TREMBL:Q8UK55 (57% identity); TREMBL:Q89NT9 (58% identity). SignalP reporting signal peptide.; Specificity unclear; putative periplasmic substrate binding protein	3077588..3078736	Azoarcus sp. BH72	4609587
YP_934299.1	CDS	azo2796	NC_008702.1	3078912	3080594	R	Similar to TREMBL:Q7WQP2 (61% identity); TREMBL:Q7W1R6 (61% identity); TREMBL:Q8G2H8 (50% identity). TIGRFAM (TIGR00786): TRAP transporter DctM subunit. TMHMM predicting 14 transmembrane helices.; Specificity unclear; putative large permease of TRAP-type transporter	complement(3078912..3080594)	Azoarcus sp. BH72	4607624
YP_934300.1	CDS	azo2797	NC_008702.1	3080591	3081184	R	Similar to TREMBL:Q7WQP3 52% identity); TREMBL:Q92P73 (54% identity); TREMBL:Q8UK53 (48% identity). TMHMM reporting four transmembrane helices.; Specificity unclear; putative small permease of TRAP-type transporter	complement(3080591..3081184)	Azoarcus sp. BH72	4607625
YP_934301.1	CDS	gpmB	NC_008702.1	3081308	3081982	D	Probable phosphoglycerate mutase GpmB (phosphoglyceromutase) 0(Pgam). Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 31% PG/BPGM_mutase. Pfam:PF00300; PGAM; 1.; High confidence in function and specificity; phosphoglycerate mutase	3081308..3081982	Azoarcus sp. BH72	4607626
YP_934302.1	CDS	kdpD1	NC_008702.1	3082083	3083501	D	Probable two component sensor protein,; High confidence in function and specificity; two component sensor protein	3082083..3083501	Azoarcus sp. BH72	4608933
YP_934303.1	CDS	kdpE	NC_008702.1	3083510	3084190	D	Transcriptional regulatory protein KdpE,; High confidence in function and specificity; two component system transcriptional regulatory protein	3083510..3084190	Azoarcus sp. BH72	4609100
YP_934304.1	CDS	glyA	NC_008702.1	3084401	3085651	D	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase	3084401..3085651	Azoarcus sp. BH72	4609102
YP_934305.1	CDS	nrdR	NC_008702.1	3085693	3086208	D	Transcriptional regulator,; Conserved hypothetical protein; transcriptional regulator NrdR	3085693..3086208	Azoarcus sp. BH72	4608924
YP_934306.1	CDS	ribD	NC_008702.1	3086189	3087280	D	Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]. CONVERTS 25-DIAMINO-6-(RIBOSYLAMINO)-4(3H)-PYRIMIDINONE 5-PHOSPHATE INTO 5-AMINO-6-(RIBOSYLAMINO)-24(1H3H)- PYRIMIDINEDIONE 5-PHOSPHATE. InterPro: Riboflavin biosynthesis protein RibD TIGRFAM: eubact_ribD: riboflavin biosynthesis protein; High confidence in function and specificity; AMP deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase	3086189..3087280	Azoarcus sp. BH72	4609726
YP_934307.1	CDS	azo2804	NC_008702.1	3087294	3088043	R	Dinucleotide-utilizing enzyme involved in molybdopterin and/or thiamine biosynthesis Belongs to the hesA/moeB/thiF family, by similarity. TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity; adenylyltransferase	complement(3087294..3088043)	Azoarcus sp. BH72	4609722
YP_934308.1	CDS	azo2805	NC_008702.1	3088140	3088598	R	Conserved hypothetical protein. Homlogy to ebA1048 Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebA1048(KEGG)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3088140..3088598)	Azoarcus sp. BH72	4607627
YP_934309.1	CDS	ctpa	NC_008702.1	3088619	3089998	R	Carboxy-terminal processing protease precursor (EC 3.4.21.102) (C- terminal processing protease). prc: carboxyl-terminal protease; High confidence in function and specificity; carboxy-terminal processing protease	complement(3088619..3089998)	Azoarcus sp. BH72	4607628
YP_934310.1	CDS	azo2807	NC_008702.1	3090060	3091394	R	Homology to peptidase, M23/M37 family InterPro: Peptidase family M23/M37; hypothetical protein	complement(3090060..3091394)	Azoarcus sp. BH72	4608541
YP_934311.1	CDS	gpmA	NC_008702.1	3091417	3092166	R	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase	complement(3091417..3092166)	Azoarcus sp. BH72	4607629
YP_934312.1	CDS	hlyU	NC_008702.1	3092165	3092641	D	Putative transcriptional activator, ArsR family,; High confidence in function and specificity; ArsR family transcriptional regulator	3092165..3092641	Azoarcus sp. BH72	4608932
YP_934313.1	CDS	azo2810	NC_008702.1	3092677	3093093	D	Similar to Rhodanese domain protein, a sulphurtransferase involved in cyanide detoxification. Hypothetical protein slr1261. InterPro: Rhodanese/cdc25 fold; Function unclear; hypothetical protein	3092677..3093093	Azoarcus sp. BH72	4609011
YP_934314.1	CDS	grxC	NC_008702.1	3093090	3093362	D	Probable glutaredoxin. Homology to grx3 of E. coli. of 53% (SWISSPROT:GLR3_ECOLI). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase. Pfam: Glutaredoxin Tigrfam: TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; High confidence in function and specificity; glutaredoxin	3093090..3093362	Azoarcus sp. BH72	4607630
YP_934315.1	CDS	secB	NC_008702.1	3093432	3093887	D	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB	3093432..3093887	Azoarcus sp. BH72	4608943
YP_934316.1	CDS	azo2813	NC_008702.1	3093892	3094338	D	Conserved hypothetical secreted protein. Homology to CV1128 of Chromobacterium violaceum of 43% (trembl:Q7NYZ4). Has Signal Peptide. Has PF06347, Protein of unknown function (DUF1058);IPR010466 ;This family consists of several hypothetical bacterial proteins of unknown function. No TMHs; Conserved hypothetical protein; hypothetical protein	3093892..3094338	Azoarcus sp. BH72	4609858
YP_934317.1	CDS	gpsA	NC_008702.1	3094335	3095324	D	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	3094335..3095324	Azoarcus sp. BH72	4607631
YP_934318.1	CDS	azo2815	NC_008702.1	3095339	3095872	R	Region start changed from 3095806 to 3095845 (39 bases); tRNA/rRNA methylase	complement(3095339..3095872)	Azoarcus sp. BH72	4608934
YP_934319.1	CDS	comF	NC_008702.1	3095879	3096571	R	Hypothetical protein yhgH. Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes, which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate SPROT:P46846: 33% identity, 51% similarity InterPro; IPR000836; PRtransferase. Pfam; PF00156; Pribosyltran; 1 Absence of Signal peptide and Transmembrane helices PPR: pentatricopeptide repeat domain; High confidence in function and specificity; putative competence protein F	complement(3095879..3096571)	Azoarcus sp. BH72	4607632
YP_934320.1	CDS	bioB	NC_008702.1	3096650	3097630	D	Biotin synthase (Biotin synthetase). catalytic activity: dethiobiotin + sulfur = biotin. cofactor: binds a 4fe-4s cluster coordinated with 3 cysteines and an exchangeable s-adenosyl-l-methionine, and a 2fe-2s cluster coordinated with 3 cysteines and 1 arginine. pathway: biotin biosynthesis; last step. similarity: belongs to the biotin and lipoic acid synthetases family. TIGRFAM: bioB: biotin synthetase; High confidence in function and specificity; biotin synthase	3096650..3097630	Azoarcus sp. BH72	4608511
YP_934321.1	CDS	bioC2	NC_008702.1	3097630	3098547	D	FUNCTION:BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin. PATHWAY:Biotin biosynthesis. SIMILARITY:Belongs to the methyltransferase superfamily TREMBL:Q7NPW6 - 46% identity,61% similarity to Chromobacterium bioC. TREMBL:Q82SL9 InterPro (IPR000051): SAM (and some other nucleotide) binding motif. Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Family membership; putative biotin synthesis protein	3097630..3098547	Azoarcus sp. BH72	4608390
YP_934322.1	CDS	ssm	NC_008702.1	3098555	3099211	D	TREMBL:Q7NQN9: 48% identity; 66% similarity SPROT:P53078: 28% identity, 47% similarity InterPro :IPR006402; HAD-SF-IA-v3. IPR005833: Hlgnase/hydrlase. IPR005834: Hydrolase. IPR010237; Pyr-5-nucltdase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs TIGR01509; HAD-SF-IA-v3; 1. TIGR01993; Pyr-5-nucltdase; SSM1 protein. No signal peptide. No transmembrane helices. Could be an enzyme that inactivates 6-azauracil by modifying it. InterPro: Haloacid dehalogenase/epoxide hydrolase family otsB: trehalose-phosphatase; Family membership; putative hydrolase	3098555..3099211	Azoarcus sp. BH72	4608392
YP_934323.1	CDS	azo2820	NC_008702.1	3099203	3099697	R	Putative acetyltransferase,42% identity to TrEMBL;Q7WFK1, Putative acetyltransferase [BB4270] [Bordetella bronchiseptica(Alcaligenes bronchisepticus)]. Has PF00583:IPR000182;Acetyltransferase (GNAT) family;This family contains proteins with N-acetyltransferase functions.Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families.; putative acetyltransferase	complement(3099203..3099697)	Azoarcus sp. BH72	4609894
YP_934324.1	CDS	hemB	NC_008702.1	3099739	3100743	R	catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase	complement(3099739..3100743)	Azoarcus sp. BH72	4607633
YP_934325.1	CDS	engB	NC_008702.1	3100989	3101618	R	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC	complement(3100989..3101618)	Azoarcus sp. BH72	4608980
YP_934326.1	CDS	cc42	NC_008702.1	3101743	3102369	D	Probable cytochrome c4. Homology to cc4 of A. vinelandii of 42% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs; High confidence in function and specificity; cytochrome C4	3101743..3102369	Azoarcus sp. BH72	4608669
YP_934327.1	CDS	azo2824	NC_008702.1	3102434	3103303	R	Hypothetical protein, 51% identity (59% similarity) to TrEMBL;Q8Y0B0. TrEMBL; Q7NWN1(53% identity). Has PF04305, Protein of unknown function (DUF455).IPR007402. Has no signal Peptide or TMH present.; Function unclear; hypothetical protein	complement(3102434..3103303)	Azoarcus sp. BH72	4608439
YP_934328.1	CDS	moeA2	NC_008702.1	3103351	3104595	D	Molybdopterin biosynthesis protein moeA. Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin) necessary for molybdo-enzymes. Seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum. InterPro: Molybdenum cofactor biosynthesis protein molyb_syn: molybdenum cofactor synthesis; High confidence in function and specificity; molybdopterin biosynthesis protein	3103351..3104595	Azoarcus sp. BH72	4607634
YP_934329.1	CDS	rpiA	NC_008702.1	3104643	3105311	D	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A	3104643..3105311	Azoarcus sp. BH72	4609258
YP_934330.1	CDS	phoU	NC_008702.1	3105356	3106069	D	Phosphate transport system protein phoU. Probably involved in phosphate transport and metabolism. In P aeruginosa PhoU is involved in the regulation of alkaline phosphatase expression and in the induction of Pi taxis.; High confidence in function and specificity; phosphate uptake regulator	3105356..3106069	Azoarcus sp. BH72	4609761
YP_934331.1	CDS	azo2828	NC_008702.1	3106151	3106423	R	Hpyothetical Protein, 69% identity (84% simialarity) to SwissProt; Q8Y010. Has PF04362, Protein of unknown function (DUF495);IPR007457;Methionine start codon is known to be cleaved from Escherichia coli protein YggX (P52065). YggX is also known to be highly abundant in E. coli K-12. No Signal peptide or TMH present.; hypothetical protein	complement(3106151..3106423)	Azoarcus sp. BH72	4609552
YP_934332.1	CDS	azo2829	NC_008702.1	3106427	3108166	R	GGDEF/PAS/PAC-domain containing protein; diguanylate cyclase	complement(3106427..3108166)	Azoarcus sp. BH72	4607635
YP_934333.1	CDS	argA	NC_008702.1	3108245	3109603	R	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase	complement(3108245..3109603)	Azoarcus sp. BH72	4607636
YP_934334.1	CDS	azo2831	NC_008702.1	3109740	3111248	R	Hypothetical protein, 53% identity (69% similarity) to TrEMBL;Q7NQR2. TREMBL;Q74F81. Has 2 copies of PF03976,IPR005660, Domain of unknown function (DUF344);This presumed domain is found in one or two copies per protein. The domain is about 230 amino acids in length and has many conserved motifs that are probably functionally important. No Signal Peptide or TMH present.; hypothetical protein	complement(3109740..3111248)	Azoarcus sp. BH72	4608331
YP_934335.1	CDS	azo2832	NC_008702.1	3111292	3112023	R	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE	complement(3111292..3112023)	Azoarcus sp. BH72	4607637
YP_934336.1	CDS	suhB2	NC_008702.1	3112072	3112881	D	Inositol-1-monophosphatase(IMPase)(Inositol-1- phosphatase)(I-1-Pase).May act by enhancing the synthesis or degradation of phosphorylated messenger molecules. Catalytic activity: myo-inositol 1-phosphate + h(2)o = myo- inositol + phosphate. 36% Inositol_P. Pfam:PF00459; Inositol_P; 1.; High confidence in function and specificity; putative inositol-1-monophosphatase	3112072..3112881	Azoarcus sp. BH72	4607638
YP_934337.1	CDS	azo2834	NC_008702.1	3112954	3113214	D	Hypothetical protein, has very weak homology with hits in the database. Has No domains, repeats, motifs or features could be predicted with confidence above threshold scores.; hypothetical protein	3112954..3113214	Azoarcus sp. BH72	4609907
YP_934338.1	CDS	prkB	NC_008702.1	3113267	3114136	D	Probable phosphoribulokinase. Homology to prkB of r. sphaeroides of 59% (sprot|KPP2_RHOSH). Phosphoribulokinase catalyses the ATP-dependent phosphorylation of ribulose-5-phosphate to ribulose-1,5-phosphate, a key step in the pentose phosphate pathway where carbon dioxide is assimilated by autotrophic organisms. InterPro: Phosphoribulokinase family (IPR006082) Pfam: Phosphoribulokinase no signal peptide no TMHs; High confidence in function and specificity; phosphoribulokinase	3113267..3114136	Azoarcus sp. BH72	4607639
YP_934339.1	CDS	tkt	NC_008702.1	3114267	3116330	D	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase	3114267..3116330	Azoarcus sp. BH72	4609629
YP_934340.1	CDS	gapA	NC_008702.1	3116428	3117444	D	Glyceraldehyde-3-phosphate dehydrogenase(GAPDH)plays an important role in glycolysis and gluconeogenesis by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho- glycerate.61% GAPDH-I.IPR000173; GAP_dhdrogenase. Pfam:PF02800; Gp_dh_C; 1.PF00044; Gp_dh_N; 1. TIGRFAMs:TIGR01534; GAPDH-I; 1.; High confidence in function and specificity; putative glyceraldehyde 3-phosphate dehydrogenase	3116428..3117444	Azoarcus sp. BH72	4609950
YP_934341.1	CDS	azo2838	NC_008702.1	3117462	3117929	D	Conserved hypothetical secreted protein. Homology to xcc3191 of X. campestris of 41% (trembl|Q8P5Z1). no domains predicted. signal peptide. no TMHs.; Function unclear; hypothetical protein	3117462..3117929	Azoarcus sp. BH72	4608858
YP_934342.1	CDS	pgk	NC_008702.1	3118003	3119187	D	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase	3118003..3119187	Azoarcus sp. BH72	4607640
YP_934343.1	CDS	azo2840	NC_008702.1	3119266	3119676	R	Hypothetical secreted protein. No good homology to the data bank. No domains predicted. Signal peptide reported to be present. No TMH reported present. ssl1: transcription factor ssl1; putative secreted protein	complement(3119266..3119676)	Azoarcus sp. BH72	4609531
YP_934344.1	CDS	azo2841	NC_008702.1	3119803	3120210	R	Conserved hypothetical membrane protein. Homology to an orf of the uncultured bacterium 463 of 33% (tremblnew|AAS07979). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(3119803..3120210)	Azoarcus sp. BH72	4607641
YP_934345.1	CDS	pykA	NC_008702.1	3120337	3121779	D	catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase	3120337..3121779	Azoarcus sp. BH72	4607642
YP_934346.1	CDS	fba	NC_008702.1	3121901	3122965	D	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase	3121901..3122965	Azoarcus sp. BH72	4609667
YP_934347.1	CDS	exaA1	NC_008702.1	3123031	3125097	R	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity; putative quinoprotein ethanol dehydrogenase	complement(3123031..3125097)	Azoarcus sp. BH72	4608729
YP_934348.1	CDS	qbdB2	NC_008702.1	3125178	3126107	R	Conserved hypothetical secreted protein. Homology to qbdB of Pseudomonas putida of 56% (gi|22779360|dbj|BAC15558.1|(NBCI ENTREZ)). No domains predicted. No TMHs. Signal peptide present.,; Conserved hypothetical protein; hypothetical protein	complement(3125178..3126107)	Azoarcus sp. BH72	4608689
YP_934349.1	CDS	azo2846	NC_008702.1	3126355	3128244	D	Similar to TREMBL:Q9F9U3 (44% identity); TREMBL:Q88H93 (39% identity); SWISSPROT:P28614 (35% identity). InterPro (IPR002078): Sigma-54 factor interaction domain. InterPro (IPR002197): Helix-turn-helix, Fis-type. InterPro (IPR003593): AAA ATPase. Pfam (PF02954): Bacterial regulatory protein, Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; sigma-54-dependent transcriptional regulator	3126355..3128244	Azoarcus sp. BH72	4609678
YP_934350.1	CDS	azo2847	NC_008702.1	3128356	3129030	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	3128356..3129030	Azoarcus sp. BH72	4607643
YP_934351.1	CDS	azo2848	NC_008702.1	3129035	3129451	D	Putative AIG2-like protein. Homology to AIG2 of a. thaliana of 27% (sprot|AIG2_ARATH) AIG2 is an Arabidopsis proteins that exhibit RPS2- and avrRpt2-dependent induction early after infection with Pseudomonas syringae pv maculicola strain ES4326 carrying avrRpt2. Pfam: AIG2-like family singal peptide no TMHs; putative AIG2-like protein	3129035..3129451	Azoarcus sp. BH72	4607644
YP_934352.1	CDS	azo2849	NC_008702.1	3129466	3131328	R	Conserved hypothetical membrane protein. Homology to AQ_563 of Aquifex aeolicus of 37% (trembl|O66835(SRS)). Has IPR003660;PF00672;HAMP domain:This domain is known as the HAMP domain for histidine kinases, adenylyl cyclases,methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160(GGDEF)domain,this domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. TMHMM reporting 1 TMH present. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(3129466..3131328)	Azoarcus sp. BH72	4607645
YP_934353.1	CDS	azo2850	NC_008702.1	3131436	3133073	R	Proline/betaine transporter (Proline porter II) (PPII). STRETCH-INACTIVATED PROLINE/BETAINE TRANSPORTER. PROP IS BOTH AN OSMOSENSOR AND AN OSMOREGULATOR WHICH IS AVAILABLE TO PARTICIPATE EARLY IN THE BACTERIAL OSMOREGULATORY RESPONSE. MEDIATES THE ACTIVE ACCUMULATION OF SOLUTES SUCH AS PROLINE GLYCINE BETAINE STACHYDRINE PIPECOLIC ACID ECTOINE AND TAURINE.PROBABLE MtbA PROTEIN 2A0106: citrate-proton symport; Specificity unclear; putative sugar transport protein	complement(3131436..3133073)	Azoarcus sp. BH72	4607646
YP_934354.1	CDS	azo2851	NC_008702.1	3133259	3134608	D	Conserved hypothetical glycerophosphoryl diester phosphodiesterase. Homology to TdenA01001091 of Thiobacillus denitrificans of 66% (gnl|keqq|mca:MCA1922(KEGG)).InterPro: Glycerophosphoryl diester phosphodiesterase (IPR004129). Pfam: Glycerophosphoryl diester phosphodiesterase. signal peptide. no TMHs; glycerophosphoryl diester phosphodiesterase	3133259..3134608	Azoarcus sp. BH72	4607647
YP_934355.1	CDS	cddD	NC_008702.1	3134727	3136160	R	Probable aldehyde dehydrogenase (NAD+). Homology to cddD of R. ruber SC1 of 59% (trembl|Q938F1) Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Pfam: Aldehyde dehydrogenase family no TMHs no signal peptide; Family membership; aldehyde dehydrogenase	complement(3134727..3136160)	Azoarcus sp. BH72	4607648
YP_934356.1	CDS	azo2853	NC_008702.1	3136366	3136650	D	Conserved hypothetical secreted protein. Homology to PA3284 of Pseudomonas aeruginosa of 40% (trembl|Q9HYV9(SRS)). No domains predicted. Signal peptide present. No TMH Present.; Conserved hypothetical protein; hypothetical protein	3136366..3136650	Azoarcus sp. BH72	4608460
YP_934357.1	CDS	azo2854	NC_008702.1	3136724	3137569	D	Conserved hypothetical protein. Homology to PA3283 of P.aeruginosa of 54% (trembl:Q9HYW0). Has PF05114,Protein of unknown function (DUF692);IPR007801:This family consists of several uncharacterised bacterial proteins. No signal peptide or TMH present.; hypothetical protein	3136724..3137569	Azoarcus sp. BH72	4607649
YP_934358.1	CDS	azo2855	NC_008702.1	3137566	3138312	D	Conserved hypothetical protein. Homology to PP2399 of P.putida of 36% (trembl:Q88K92). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	3137566..3138312	Azoarcus sp. BH72	4607650
YP_934359.1	CDS	azo2856	NC_008702.1	3138309	3138881	D	Conserved hypothetical membrane protein. Homology to PA4104 of Pseudomonas aeruginosa of 46% (trembl|Q9HWS4(SRS)). No domains predictec. no signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	3138309..3138881	Azoarcus sp. BH72	4607651
YP_934360.1	CDS	sigX	NC_008702.1	3138878	3139468	D	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor	3138878..3139468	Azoarcus sp. BH72	4607652
YP_934361.1	CDS	azo2858	NC_008702.1	3139462	3139650	D	Conserved hypothetical protein. Homology to CV2972 of C.violaceum of 51% (trembl:Q7NTT1). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	3139462..3139650	Azoarcus sp. BH72	4609869
YP_934362.1	CDS	estB	NC_008702.1	3139801	3140484	D	Probable carboxylesterase. Homology to estB of P. flourescens of 41% (sprot|EST2_PSEFL). Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity. InterPro: Phospholipase/Carboxylesterase(IPR003140); Esterase/lipase/ thioesterase family acitve site (IPR000379) Pfam: Phospolipase/Carboxylesterase no signal peptide no TMHs; High confidence in function and specificity; carboxylesterase	3139801..3140484	Azoarcus sp. BH72	4607653
YP_934363.1	CDS	azo2860	NC_008702.1	3140490	3141521	R	Conserved hypothetical membrane protein. Homology to PJS6w01004232 of Polaromonas sp. JS666 of 53% (gi|54028976|ref|ZP_00361120.1|(NBCI ENTREZ)). InterPro:IPR002035; VWF_A. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA; 1. PROSITE:PS50234; VWFA; MIP: MIP family channel proteins. No signal peptide present. No. of TMH's: 3 (TMHMM predicted).; Conserved hypothetical protein; hypothetical protein	complement(3140490..3141521)	Azoarcus sp. BH72	4608675
YP_934364.1	CDS	azo2861	NC_008702.1	3141518	3142456	R	Hypothetical protein Rv1480/MT1527/Mb1516. TREMBL:Q7MUE8: 33% identity, 52% similarity. This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterPro: IPR002881; DUF58. Pfam: PF01882; DUF58 Absence of transmembrane helices (TMHMM predicted) cmk: cytidylate kinase; Specificity unclear; hypothetical protein	complement(3141518..3142456)	Azoarcus sp. BH72	4607654
YP_934365.1	CDS	moxR2	NC_008702.1	3142431	3143453	R	MoxR protein (MxaR protein). MAY BE INVOLVED IN THE REGULATION OF FORMATION OF ACTIVE METHANOL DEHYDROGENASE. TREMBLnew:CAE55395: 54% identity, 71% similarity InterPro:IPR003593; AAA_ATPase. IPR000523; Mg_chelatse_chII. Pfam PF01078; Mg_chelatase; 1. SMART SM00382; AAA; 1 InterPro IPR003593; AAA_ATPas ruvB: Holliday junction DNA helicase Ru; High confidence in function and specificity; MoxR protein	complement(3142431..3143453)	Azoarcus sp. BH72	4607655
YP_934366.1	CDS	azo2863	NC_008702.1	3143481	3144263	R	Conserved hypothetical serine protease. Homology to PJS6w01004229 of Polaromonas sp. JS666 of 53% (gi|54028973|ref|ZP_00361117.1|(NBCI ENTREZ)). Interpro: HtrA/DegQ protease family (IPR001940); Serine protease,trypsine family (IPR001254). Pfam: Typsin. probable signal peptide. no TMHs; Conserved hypothetical protein; putative serine protease	complement(3143481..3144263)	Azoarcus sp. BH72	4609265
YP_934367.1	CDS	azo2864	NC_008702.1	3144672	3145691	D	Conserved hypothetical membrane protein. TREMBL:Q9CBL9: 33% identity; 52% similarity The von Willebrand factor is a large multimeric glycoprotein found in bloodplasma. Mutant forms are involved in the aetiology of bleeding disorders. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily Hypothetical protein MAV335. InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. SMART:SM00327; VWA 2_A_01_02: Multidrug resistance protein Presence of Signal peptide (SignalP predicted) Presence of 3 transmembrane helices (TMHMM predicted).; Conserved hypothetical protein; hypothetical protein	3144672..3145691	Azoarcus sp. BH72	4607656
YP_934368.1	CDS	azo2865	NC_008702.1	3145796	3146101	D	Conserved hypothetical protein. Homology to CE0355 of C.efficiens of 56% (trembl:Q8FSM8). No domains predicted. No THs. No signal peptide.; hypothetical protein	3145796..3146101	Azoarcus sp. BH72	4607657
YP_934369.1	CDS	azo2866	NC_008702.1	3146175	3147203	D	GGDEF/PAS/PAC-domain containing protein; diguanylate cyclase	3146175..3147203	Azoarcus sp. BH72	4607658
YP_934370.1	CDS	azo2867	NC_008702.1	3147200	3148141	R	Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 44% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear; LysR family transcriptional regulator	complement(3147200..3148141)	Azoarcus sp. BH72	4607659
YP_934371.1	CDS	ygiD	NC_008702.1	3148259	3149065	D	Putative cytoplasmic protein ygiD, 35% identity to TrEMBL;Q8ZLZ3. TrEMBL;Q8XBP3,Q83JK6. Has PF02900,Catalytic LigB subunit of aromatic ring-opening dioxygenase;IPR004183:The LigAB enzyme (a protocatechuate 4,5-dioxygenase), of Sphingomonas paucimobilis oxidizes protocatechuate (or 3,4-dihydroxybenzoic acid, PCA). The enzyme belongs to the class III extradiol-type catecholic dioxygenase family, which catalyzes the ring-opening reaction of protocatechuate and related compounds.; Conserved hypothetical protein; protocatechuate 4,5-dioxygenase	3148259..3149065	Azoarcus sp. BH72	4607660
YP_934372.1	CDS	azo2869	NC_008702.1	3149082	3149636	D	Conserved hypothetical cytochrome B561. Homology to cv3278 of C. violaceum of 69% (trembl|Q7NSZ1). Involved in electronen transport. no domains reported. no signal peptide. 4 TMHs; Family membership; cytochrome B561	3149082..3149636	Azoarcus sp. BH72	4610179
YP_934373.1	CDS	azo2870	NC_008702.1	3149682	3150251	D	Conserved hypothetical YceI like protein. Homology to CV3277 of C.violaceum of 51% (tremble:Q7NSZ2). Has PF04264, YceI like family;(IPR007372): E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	3149682..3150251	Azoarcus sp. BH72	4607661
YP_934374.1	CDS	azo2871	NC_008702.1	3150311	3150889	D	Conserved hypothetical YceI like protein. Homology to cv3276 of C. violaceum of 69% (trembl|Q7NSZ3(SRS)) Pfam: YceI like family E. coli. YceI is a base-induced periplasmic protein. Its function has not yet been characterised. signal peptide. no TMHs; Family membership; hypothetical protein	3150311..3150889	Azoarcus sp. BH72	4607662
YP_934375.1	CDS	azo2872	NC_008702.1	3151019	3152311	D	Conserved hypothetical membrane protein. Homology to NE1887 of Nitrosomonas europaea of 39% (trembl|Q82TK0). No domains predicted. No signal peptide. TMHMM2 program predicts presence of 1 TMH's.; Conserved hypothetical protein; hypothetical protein	3151019..3152311	Azoarcus sp. BH72	4607663
YP_934376.1	CDS	purC	NC_008702.1	3152720	3153655	D	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase	3152720..3153655	Azoarcus sp. BH72	4607664
YP_934377.1	CDS	azo2874	NC_008702.1	3153726	3154457	R	Conserved hypothetical protein. Homology to AGR_C_1551 of A.tumefaciens of 40% (trembl:Q7D0J2). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(3153726..3154457)	Azoarcus sp. BH72	4609656
YP_934378.1	CDS	azo2875	NC_008702.1	3154417	3154797	R	Conserved hypothetical protein, 67% similarity to TrEMBL:Q8UH3. No good homology with hits in the DB particularly at the start. Signal peptide reported present. No TMH present.; Family membership; hypothetical protein	complement(3154417..3154797)	Azoarcus sp. BH72	4607665
YP_934379.1	CDS	azo2876	NC_008702.1	3155005	3155778	D	Conserved hypothetical membrane protein. Homology to cv3790 of C. violaceum of 36% (cvi:CV3790(KEGG). no domains predicted. no signal peptide. 6 TMHs.; Conserved hypothetical protein; hypothetical protein	3155005..3155778	Azoarcus sp. BH72	4607666
YP_934380.1	CDS	prlC	NC_008702.1	3155906	3157972	D	Oligopeptidase A counts to the Thimet oligopeptidase family which cleave medium sized peptides. Similar to trembl|Q7VZC9 (49%), to trembl|Q9JX57 (48%) and to sprot|OPDA_ECOLI (51%). Pfam (PF01432): Peptidase family M3; Specificity unclear; oligopeptidase A	3155906..3157972	Azoarcus sp. BH72	4607667
YP_934381.1	CDS	azo2878	NC_008702.1	3157969	3158451	D	Low similiraty to glutaredoxin protein Grx. Has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase.Reduces low molecular weight disulfides and proteins (by similarity). Hypothetical protein yjbD. Signal peptide; Function unclear; hypothetical protein	3157969..3158451	Azoarcus sp. BH72	4609630
YP_934382.1	CDS	amtE	NC_008702.1	3158471	3161860	R	Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 12 transmembrane helices (TMHMM predicted).; Specificity unclear; ammonia permease	complement(3158471..3161860)	Azoarcus sp. BH72	4607668
YP_934383.1	CDS	azo2880	NC_008702.1	3162198	3162959	D	Region start changed from 3161811 to 3162171 (-360 bases); exodeoxyribonuclease III	3162198..3162959	Azoarcus sp. BH72	4608318
YP_934384.1	CDS	azo2881	NC_008702.1	3162965	3163681	D	Hypothetical protein, has weak homology with other hits in the Database. TrEMBL;Q67LU3(34%). Has Signal Peptide.; hypothetical protein	3162965..3163681	Azoarcus sp. BH72	4607669
YP_934385.1	CDS	nnr	NC_008702.1	3163695	3164381	D	Putative transcription regulator, Nnr-type.; Family membership; putative transcription regulator, Nnr-type	3163695..3164381	Azoarcus sp. BH72	4607670
YP_934386.1	CDS	azo2883	NC_008702.1	3164450	3164641	D	Conserved hypothetical secreted protein. Homology to RPA1091 of R.palustris of 57% (tremble:CAE26534). No domains predicted. No TMH. signal peptide present.; Conserved hypothetical protein; hypothetical protein	3164450..3164641	Azoarcus sp. BH72	4609386
YP_934387.1	CDS	ksgA	NC_008702.1	3164700	3165497	R	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase	complement(3164700..3165497)	Azoarcus sp. BH72	4607671
YP_934388.1	CDS	pdxA	NC_008702.1	3165517	3166509	R	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase	complement(3165517..3166509)	Azoarcus sp. BH72	4609107
YP_934389.1	CDS	surA	NC_008702.1	3166514	3167833	R	Putative peptidyl-prolyl cis-trans isomerase. Homology to surA of E. coli of 32% (sprot|SURA_ECOLI). Assist in the folding of extracytoplasmic proteins. Essential for the survival of E.coli in stationary phase. Pfam: PPIC-type PPIASE domain signal peptide no TMHs; Family membership; putative peptidyl-prolyl cis-trans isomerase	complement(3166514..3167833)	Azoarcus sp. BH72	4609516
YP_934390.1	CDS	ostA	NC_008702.1	3167868	3169991	R	Organic solvent tolerance protein precursor.; High confidence in function and specificity; organic solvent tolerance protein	complement(3167868..3169991)	Azoarcus sp. BH72	4609910
YP_934391.1	CDS	azo2888	NC_008702.1	3170525	3171544	D	Conserved hypothetical protein. Homology to ne0191 of N. europaea of 61% (trembl|Q82XR3). Pfam: DUF227. no signal peptide. no TMHs.; hypothetical protein	3170525..3171544	Azoarcus sp. BH72	4609460
YP_934392.1	CDS	azo2889	NC_008702.1	3171570	3172298	D	Specificity unclear; nucleotidyltransferase	3171570..3172298	Azoarcus sp. BH72	4607672
YP_934393.1	CDS	pepP	NC_008702.1	3172306	3173652	D	Xaa-Pro aminopeptidase,; Specificity unclear; Xaa-Pro aminopeptidase	3172306..3173652	Azoarcus sp. BH72	4607673
YP_934394.1	CDS	ubiH	NC_008702.1	3173642	3174805	D	ubiH; aromatic-ring hydroxylase (flavoprotein monooxygenase) Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. Ubiquinone biosynthesis pathway, by similarity.; High confidence in function and specificity; 2-octaprenyl-6-methoxyphenol hydroxylase	3173642..3174805	Azoarcus sp. BH72	4609523
YP_934395.1	CDS	dusB	NC_008702.1	3174872	3175945	D	Conserved hypothetical tRNA-dihydrouridine synthase. Homology to dusB of Azoarcus sp. EbN1 of 81% (gnl|keqq|eba:ebA1152(KEGG)). Pfam: Dihydrouridine synthase (Dus). Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archae. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities, which may overlap. Dus 1 (Q9HGN6) from Saccharomyces cerevisiae acts on pre-tRNA-Phe, while Dus 2 (P53720) acts on pre-tRNA-Tyr and pre-tRNA-Leu. Dus 1 is active as a single subunit, requiring NADPH or NADH, and is stimulated by the presence of FAD. Some family members may be targeted to the mitochondria and even have a role in mitochondria. No signal peptide. No TMHs; Conserved hypothetical protein; putative tRNA-dihydrouridine synthase	3174872..3175945	Azoarcus sp. BH72	4610061
YP_934396.1	CDS	azo2893	NC_008702.1	3175942	3176178	D	Putative fis-like DNA-binding protein, 57% Identity to SwissProt;Q8Y231,TrEMBL;Q7P0M2(58% Identity). Has PF02954, Bacterial regulatory protein, Fis family;IPR002197 HTH_Fis; The Factor for Inversion Stimulation (FIS) protein is a regulator of bacterial functions, and binds specifically to weakly related DNA sequences. It activates ribosomal RNA transcription, and is involved in upstream activation of rRNA promoters. The protein has been shown to play a role in the regulation of virulence factors in both Salmonella typhimurium and Escherichia coli. Some of its functions include inhibition of the initiation of DNA replication from the OriC site,and promotion of Hin-mediated DNA inversion.; putative fis-like DNA-binding protein	3175942..3176178	Azoarcus sp. BH72	4608656
YP_934397.1	CDS	purH	NC_008702.1	3176279	3177862	D	involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	3176279..3177862	Azoarcus sp. BH72	4607674
YP_934398.1	CDS	purD	NC_008702.1	3177876	3179153	D	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase	3177876..3179153	Azoarcus sp. BH72	4609660
YP_934399.1	CDS	hemF	NC_008702.1	3179160	3180074	D	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase	3179160..3180074	Azoarcus sp. BH72	4609657
YP_934400.1	CDS	sulP1	NC_008702.1	3180121	3181881	D	Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present. HIGH-AFFINITY H+/SULFATE COTRANSPORTER THAT MEDIATES THE UPTAKE OF SULFATE BY PLANT ROOTS FROM LOW CONCENTRATIONS OF SULFATE IN THE SOIL SOLUTION.; High confidence in function and specificity; putative sulfate transporter	3180121..3181881	Azoarcus sp. BH72	4608984
YP_934401.1	CDS	rpsP	NC_008702.1	3181964	3182215	D	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16	3181964..3182215	Azoarcus sp. BH72	4609908
YP_934402.1	CDS	rimM	NC_008702.1	3182235	3182741	D	Conserved hypothetical 16S rRNA processing protein rimM. Homology to rimM of R. solanacearum of 44% (sprot|RIMM_RALSO). Essential for efficient processing of 16S rRNA. Probably part of the 30S subunit prior to or during the final step in the processing of 16S free 30S ribosomal subunits. It could be some accessory protein needed for efficient assembly of the 30S subunit. It is needed in a step prior to rbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes. Pfam: RimM. no signal peptide. no TMHs; High confidence in function and specificity; 16S rRNA processing protein	3182235..3182741	Azoarcus sp. BH72	4609819
YP_934403.1	CDS	trmD	NC_008702.1	3182723	3183535	D	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase	3182723..3183535	Azoarcus sp. BH72	4609728
YP_934404.1	CDS	rplS	NC_008702.1	3183621	3184007	D	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19	3183621..3184007	Azoarcus sp. BH72	4609973
YP_934405.1	CDS	azo2902	NC_008702.1	3184128	3185204	R	TREMBL:Q8XWQ6: 39% identity, 56% similarity Hypothetical protein HI1703. InterPro: IPR005495; YjgP_YjgQ. Pfam: PF03739;Pfam :DUF214:Predicted permease Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long, contain about 6 transmembrane regions and may be permeases, although there is no verification of this. subcellular location:integral membrane protein (potential). similarity:strong, to h.influenzae hi1703 2a69: Auxin Efflux Carrier TMHMM predicted 6 transmembrane helices; Conserved hypothetical protein; integral membrane protein	complement(3184128..3185204)	Azoarcus sp. BH72	4609778
YP_934406.1	CDS	azo2903	NC_008702.1	3185201	3186280	R	Conserved hypothetical membrane protein. TREMBL:Q8XWQ7: 40% identity; 55% similarity: probable integral membrane protein InterPro:IPR005495; YjgP_YjgQ. Pfam:PF03739; YjgP_YjgQ :UbiA : UbiA prenyltransferase family Pfam:DUF112:Integral membrane protein DUF112 Signal peptide present (Signal P predicted). Transmembrane helices: 5 (TMHMM predicted).; Conserved hypothetical protein; hypothetical protein	complement(3185201..3186280)	Azoarcus sp. BH72	4607675
YP_934407.1	CDS	pepA	NC_008702.1	3186423	3187925	D	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase	3186423..3187925	Azoarcus sp. BH72	4607676
YP_934408.1	CDS	holC	NC_008702.1	3187931	3188368	D	Putative DNA polymerase III chi subunit, 40% Identity to TrEMBL; Q8XWQ9,Q63WC2,Q62LH1. Has PF04364, DNA polymerase III chi subunit, HolC;IPR007459, DNA_pol3_chi; The DNA polymerase III holoenzyme is the polymerase responsible for the replication of the Escherichia coli chromosome. The holoenzyme is composed of the DNA polymerase III core, the sliding clamp, and the DnaX clamp loading complex. The DnaX complex contains either either the tau or gamma product of gene dnax, complexed to delta.delta' and to chi psi. Chi forms a 1:1 heterodimer with psi. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' allowing a functional clamp-loading complex to form at physiological subunit concentrations. Psi is responsible for the interaction with DnaX (gamma/tau), but psi is insoluble unless it is in a complex with chi.; DNA-directed DNA polymerase	3187931..3188368	Azoarcus sp. BH72	4609519
YP_934409.1	CDS	azo2906	NC_008702.1	3188383	3188892	D	Conserved hypothetical protein. Homology to ebA7176 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA7176(KEGG)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	3188383..3188892	Azoarcus sp. BH72	4609014
YP_934410.1	CDS	valS	NC_008702.1	3188987	3191983	D	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase	3188987..3191983	Azoarcus sp. BH72	4607677
YP_934411.1	CDS	azo2908	NC_008702.1	3192016	3192657	R	Putative TetR family transcriptional regulator,; Family membership; TetR family transcriptional regulator	complement(3192016..3192657)	Azoarcus sp. BH72	4610089
YP_934412.1	CDS	azo2909	NC_008702.1	3192663	3193847	R	Similar to TREMBL:Q82VH0 (64% identity); TREMBL:Q9HTW0 (63% identity); TREMBL:Q8FZX1 (64% identity). TMHMM predicting seven transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Specificity unclear; ABC transporter permease	complement(3192663..3193847)	Azoarcus sp. BH72	4607678
YP_934413.1	CDS	azo2910	NC_008702.1	3193878	3196646	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transporter. TMHMM predicting five transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity; ABC transporter permease and ATP-binding protein	complement(3193878..3196646)	Azoarcus sp. BH72	4607679
YP_934414.1	CDS	azo2911	NC_008702.1	3196643	3197716	R	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q8ZLD9 (56% identity); TREMBL:Q8VR08 (56% identity). Pfam (PF00529): HlyD family secretion protein. SignalP reporting signal peptide. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership; membrane fusion protein	complement(3196643..3197716)	Azoarcus sp. BH72	4607680
YP_934415.1	CDS	oprM3	NC_008702.1	3197732	3199141	R	Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 47%. Component of an efflux system that confers multidrug or multible antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Family membership; outer membrane efflux protein	complement(3197732..3199141)	Azoarcus sp. BH72	4607681
YP_934416.1	CDS	fimT	NC_008702.1	3199640	3200071	D	In P. aeruginosa fimT and fimU genes contain prepilin-like leader sequences. FimT plays probable a role in fimbrial biogenesis. Similar to trembl|Q87FA9 (30%). Pfam (PF00114): Pilin (bacterial filament) TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear; putative pre-pilin like protein	3199640..3200071	Azoarcus sp. BH72	4609455
YP_934417.1	CDS	pilV	NC_008702.1	3200061	3200528	D	In P. aeruginosa the genes pilV and pilE encode prepilin-like proteins involved in type 4 fimbrial biogenesis. Similar to trembl|Q8PJ74 (46%). SignalP reporting Signal Peptide.; Function unclear; putative prepilin-like protein	3200061..3200528	Azoarcus sp. BH72	4608763
YP_934418.1	CDS	azo2915	NC_008702.1	3200534	3201547	D	Conserved hypothetical protein; hypothetical protein	3200534..3201547	Azoarcus sp. BH72	4609576
YP_934419.1	CDS	pilX	NC_008702.1	3201544	3202113	D	In P. aeruginosa the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These genes are involved in the assembly of type 4 fimbriae. Similar to trembl|Q8PJ76 (34%). TMHMM reporting one TMH. SignalP reporting Signal peptide.; Function unclear; putative Tfp pilus assembly protein	3201544..3202113	Azoarcus sp. BH72	4607682
YP_934420.1	CDS	pilY1B	NC_008702.1	3202121	3206329	D	PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. PilY1 appears to be located in both the membrane and the external fimbrial fractions. Similar to pir|H82802 (39%). SignalP reporting Signal peptide; Function unclear; putative Tfp pilus assembly protein	3202121..3206329	Azoarcus sp. BH72	4609578
YP_934421.1	CDS	pilE	NC_008702.1	3206332	3206736	D	In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similar to trembl|Q82TX3 (50%) and to pir|G82857 (43%). Pfam (PF00114): Pilin (bacterial filament) SignalP reporting Signal peptide. TMHMM reporting one Tmhelix; Function unclear; putative prepilin like protein	3206332..3206736	Azoarcus sp. BH72	4609580
YP_934422.1	CDS	azo2919	NC_008702.1	3206799	3207029	R	Conserved hypothetical protein. Homology to rsc0810 of R. solanacearum of 71% (trembl|Q8Y180). InterPro: Uncharacterized protein family UPF0033 (IPR001455). Pfam: Uncharacterized protein family UPF0033. no signal peptide. no TMH; Family membership; hypothetical protein	complement(3206799..3207029)	Azoarcus sp. BH72	4609559
YP_934423.1	CDS	azo2920	NC_008702.1	3207107	3208546	R	Conserved hypothetical protein. Homology to cv0524 C. violaceum of 42% (trembl|Q7P0P2). Pfam: Peptidase family M48. signal peptide. no TMHs; peptidase	complement(3207107..3208546)	Azoarcus sp. BH72	4607683
YP_934424.1	CDS	moaC	NC_008702.1	3208627	3209139	D	Molybdenum cofactor biosynthesis protein C. Together with moaA is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z (By similarity). InterPro: MoaC family moaC: molybdenum cofactor biosynthesis protein C.; High confidence in function and specificity; molybdenum cofactor biosynthesis protein C	3208627..3209139	Azoarcus sp. BH72	4607684
YP_934425.1	CDS	azo2922	NC_008702.1	3209384	3209602	D	Conserved hypothetical protein. Homology to orf11 of A. vinelandii of 63% (trembl|Q44537). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	3209384..3209602	Azoarcus sp. BH72	4609242
YP_934426.1	CDS	tupC	NC_008702.1	3209702	3210415	R	Probable ATP-binding component of tungstate ABC transporter. Homology to tupC of E. acidaminophilum of 40% (tremble: Q93KD4). PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR tungstate. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: ABC transporter Interpo: ABC-transporter (IPR003439), AAA-ATPase (IPR003593), ATP/GTP-binding site motif A (loopP) (IPR001687) no signal peptide no TMHS; Family membership; tungstate ATP-binding protein	complement(3209702..3210415)	Azoarcus sp. BH72	4607685
YP_934427.1	CDS	tupB	NC_008702.1	3210426	3211130	R	Probable tungstate permease. Homology to tupB of E. acidaminophilum of 40% (tremble: Q93KD5) Permase of an abc-transport system involved in transport of oxyanions. no signal peptide probable 5 TMHs; Family membership; tungstate permease	complement(3210426..3211130)	Azoarcus sp. BH72	4610051
YP_934428.1	CDS	azo2925	NC_008702.1	3211273	3211878	D	Hypothetical secredted protein. no homology of the entire protein to the data bank. no domains predicted signal peptide no TMHs; hypothetical protein	3211273..3211878	Azoarcus sp. BH72	4610050
YP_934429.1	CDS	azo2926	NC_008702.1	3211901	3212554	D	Conserved hypothetical secreted protein. Homology to orf of P.aeruginosa of 30% (ZP_00137401). No domains predicted. Signal peptide reported present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	3211901..3212554	Azoarcus sp. BH72	4607686
YP_934430.1	CDS	azo2927	NC_008702.1	3212572	3212877	R	Conserved hypothetical protein. Homology to ebA5010 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebA5010(KEGG)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3212572..3212877)	Azoarcus sp. BH72	4607687
YP_934431.1	CDS	azo2928	NC_008702.1	3212888	3213139	R	Conserved hypothetical protein. Homology to Rgel02003612 of Rubrivivax gelatinosus PM1 of 51% (gi|47572157|ref|ZP_00242203.1|(NBCI ENTREZ)). Pfam: This family ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. This family of proteins have two conserved Glycines at the COOH terminus. MoaD, a protein involved sulphur transfer in molybdopterin synthesis, is about the same length and shows limited sequence similarity to ThiS. Both have the conserved GG at the COOH end. no signal peptide. no TMHs; hypothetical protein	complement(3212888..3213139)	Azoarcus sp. BH72	4607688
YP_934432.1	CDS	azo2929	NC_008702.1	3213150	3214418	R	Putative oxidoreductase. Homology to narC of C. perfringens of 27% (trembl|Q9WX91) InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327) Pfam: Pyridine nucleotide-disulfide oxidoreductase no signal peptide no TMHs purD: phosphoribosylamine--glycine lig; Family membership; putative oxidoreductase	complement(3213150..3214418)	Azoarcus sp. BH72	4607689
YP_934433.1	CDS	aorA	NC_008702.1	3214510	3216357	R	Probable aldehyde ferredoxin oxidoreductase. Homology to aorA of E. acidodaminophilum of 47% (trembl|Q93KC8) InterPro: Aldehyde ferredoxin oxidoreductase (IPR001203) Pfam: Aldehyde ferredoxin oxidoreductase, N-terminus; Aldeyhde ferredoxin oxidoreductase, damains 2&3 no TMHs no signal peptide; High confidence in function and specificity; aldehyde ferredoxin oxidoreductase	complement(3214510..3216357)	Azoarcus sp. BH72	4607690
YP_934434.1	CDS	azo2931	NC_008702.1	3216368	3216844	R	Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; hypothetical protein	complement(3216368..3216844)	Azoarcus sp. BH72	4608322
YP_934435.1	CDS	azo2932	NC_008702.1	3216979	3219003	R	Similar to TREMBL:Q8XUQ7 (42% identity); TREMBL:Q8PPN1 (40% identity); SWISSPROT:P28614 (37% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; sigma-54 dependent transcriptional regulator	complement(3216979..3219003)	Azoarcus sp. BH72	4607691
YP_934436.1	CDS	exaB1	NC_008702.1	3219326	3219763	D	Probable cytochrome c550. Homology to exaB of P. aeruginosa of 57% (trembl|Q9Z4P8) Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system InterPro: Cytochrome c class I ((IPR003088) Pfam: Cytochrome c signal peptide no TMHs; High confidence in function and specificity; cytochrome c550	3219326..3219763	Azoarcus sp. BH72	4607692
YP_934437.1	CDS	azo2934	NC_008702.1	3219753	3220616	D	Conserved hypothetical amino acid-binding protein. Homology to pp2676 of P. putida of 34% (trembl|Q88JH3). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR amino acids. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638); solute binding protein /glutamate receptor (IPR001311). Pfam: Bacterial extracellular solute-binding protein. singal peptide. no TMHs; Specificity unclear; amino acid-binding protein	3219753..3220616	Azoarcus sp. BH72	4608694
YP_934438.1	CDS	azo2935	NC_008702.1	3220743	3221693	D	Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and receptor recognition.; Function unclear; hypothetical protein	3220743..3221693	Azoarcus sp. BH72	4607693
YP_934439.1	CDS	azo2936	NC_008702.1	3221690	3222226	D	Conserved hypothetical cytochrome B561. Homology to cv3278 of C. violaceum of 41%. Involved in electronen transfer. no domains. no signal peptide. 4 TMHs; Family membership; cytochrome B561	3221690..3222226	Azoarcus sp. BH72	4607694
YP_934440.1	CDS	cyt1	NC_008702.1	3222295	3222618	R	Probable cytochrome c-552 precursor. Homology to cyt of N. europaea of 50% (sprot|C552_NITEU). ELECTRON DONOR FOR CYTOCHROME CD1 IN NITRITE AND NITRATE RESPIRATION. InterPro: Cytochrome c class I (IPR003088); Cytochrome c, class ID (IPR002324); cytochrome c, class IC (IPR008168) Pfam: cytochrome c signal peptide no TMHs; High confidence in function and specificity; cytochrome c-552 precourser	complement(3222295..3222618)	Azoarcus sp. BH72	4607695
YP_934441.1	CDS	azo2938	NC_008702.1	3222672	3223040	R	Conserved hypothetical protein. Homology to OB2533 of O.iheyensis of 64% (trembl:Q8ENF0). Has PF05610,Protein of unknown function (DUF779);IPR008497;This family consists of several bacterial proteins of unknown function. No signal peptide or TMH present.; hypothetical protein	complement(3222672..3223040)	Azoarcus sp. BH72	4608567
YP_934442.1	CDS	aldA	NC_008702.1	3223255	3224775	R	Aldehyde dehydrogenase (NAD+). Homology to aldA of X. autotrophicus of 76% (trembl|O50203). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no TMHs; High confidence in function and specificity; aldehyde dehydrogenase	complement(3223255..3224775)	Azoarcus sp. BH72	4607696
YP_934443.1	CDS	azo2940	NC_008702.1	3225116	3226705	D	Similar to TREMBL:Q7P122 (29% identity); TREMBL:Q87YQ3 (29% identity); SWISSPROT:P28614 (28% identity). Pfam (PF00158): Sigma-54 interaction domain.; Specificity unclear; sigma-54 dependent transcriptional regulator	3225116..3226705	Azoarcus sp. BH72	4608294
YP_934444.1	CDS	zitB	NC_008702.1	3226773	3227456	R	Zinc transporter zitB (formaly ybgR).Involved in zinc efflux across the cytoplasmic membrane thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc (By similarity).The E.coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family.; High confidence in function and specificity; putative zinc transport protein	complement(3226773..3227456)	Azoarcus sp. BH72	4607697
YP_934445.1	CDS	azo2942	NC_008702.1	3227685	3229697	D	Conserved hypothetical protein. Homology to PSPTO5055 of P.syringae of 36% (trembl:Q87V84). No domains predicted. No signal peptide or TMH reported present.; hypothetical protein	3227685..3229697	Azoarcus sp. BH72	4610201
YP_934446.1	CDS	azo2943	NC_008702.1	3230033	3231325	D	Conserved hypothetical protein. Homology to PSPTO5054 of P.syringae of 35% (trembl:Q87V85). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	3230033..3231325	Azoarcus sp. BH72	4607698
YP_934447.1	CDS	azo2944	NC_008702.1	3231339	3231797	R	Conserved hypothetical secreted protein. Homology to ws0556 of W. succinogenes of 51% (trembl|Q7MSD6). Pfam: DUF411. The function of the members of this bacterial protein family is unknown. Some members may be involved in conferring cation resistance. signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3231339..3231797)	Azoarcus sp. BH72	4607699
YP_934448.1	CDS	copS	NC_008702.1	3231842	3233239	R	Two component sensor kinase,; High confidence in function and specificity; two component sensor kinase	complement(3231842..3233239)	Azoarcus sp. BH72	4607700
YP_934449.1	CDS	copR	NC_008702.1	3233236	3233916	R	Transcriptional activator protein,; High confidence in function and specificity; two component response regulator	complement(3233236..3233916)	Azoarcus sp. BH72	4608515
YP_934450.1	CDS	azo2947	NC_008702.1	3234103	3234528	D	Conserved hypothetical secreted protein. Homology to pp5391 of P. putida of 31% (trembl|Q88BZ2). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein; hypothetical protein	3234103..3234528	Azoarcus sp. BH72	4608514
YP_934451.1	CDS	azo2948	NC_008702.1	3234590	3234883	D	AAH:63279: 42% identity, 55% similarity Anti-oncogene; SH3 domain; Repeat; Description:SAM and SH3 domains containing protein 1 (proline-glutamate repeat-containing protein). Gene name(s) sash1 or pepe1 contains 1 SH3 domain. similarity: contains 2 sterile alpha motif (SAM) domains May have a role in a signaling pathway. Could act as a tumor supressor. InterPro: IPR001660; SAM. IPR001452: SH3. Pfam:PF00536; SAM; 2. PF00018:SH3; 1. SMART:SM00454; SAM; Function unclear; putative hydrolase	3234590..3234883	Azoarcus sp. BH72	4607701
YP_934452.1	CDS	czcC	NC_008702.1	3234880	3236301	D	Putative outer membrane efflux protein involved in cobalt-zinc-cadmium resistance (Cation efflux system protein czcC). Homology to czcC of R. eutropha of 24%. czcC protein appears to modify the specificity of the system perhaps by acting on the czcB protein. When the czcC protein is added to czcA and czcB the efflux systems gained specificity for Cd(2+)and Co(2+) signal peptide no TMHs; Family membership; putative metal ion efflux outer membrane protein	3234880..3236301	Azoarcus sp. BH72	4607702
YP_934453.1	CDS	azo2950	NC_008702.1	3236323	3237729	D	Multicopper oxidases are enzymes that possess three spectroscopically differentcopper centers. Similar to TREMBL:Q7X4G1 (71% identity); TREMBL:Q8U8U7 (71% identity); TREMBL:Q92ZC7 (70% identity). InterPro (IPR001117): Multicopper oxidase type 1. Pfam (PF00394): Multicopper oxidase. SignalP reporting signal peptide.; Function unclear; multicopper oxidase	3236323..3237729	Azoarcus sp. BH72	4608572
YP_934454.1	CDS	azo2951	NC_008702.1	3237804	3238304	D	CopC: copper tolerance protein.CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm. 43% Cu-oxidase. InterPro:IPR008972; Cupredoxin. Signal pepetide:present. TMhelix:1.; Function unclear; putative copper tolerance protein	3237804..3238304	Azoarcus sp. BH72	4607703
YP_934455.1	CDS	azo2952	NC_008702.1	3238418	3238759	D	Conserved hypothetical secreted protein. Homology to SMc02284 of S. meliloti of 38% (trembl|Q92S41(SRS)). Has PF07076:IPR009780;Protein of unknown function (DUF1344):This family consists of several short,hypothetical bacterial proteins of around 80 residues in length. Members of this family are found in Rhizobium,Agrobacterium and Brucella species. The function of this family is unknown. Signal peptide predicted. No TMHs; Conserved hypothetical protein; hypothetical protein	3238418..3238759	Azoarcus sp. BH72	4607704
YP_934456.1	CDS	azo2953	NC_008702.1	3238999	3240282	D	Conserved hypothetical outer membrane efflux. Homology to ebA2169 Azoarcus sp. EbN1 of 68% (gnl|keqq|eba:ebA2169(KEGG)). Pfam: Outer membrane efflux protein. signal peptide. probable 1 TMH in signal peptide.; Conserved hypothetical protein; outer membrane efflux protein	3238999..3240282	Azoarcus sp. BH72	4607705
YP_934457.1	CDS	cusB	NC_008702.1	3240279	3241874	D	Putative membrane fusion protein silB precursor. COMPONENT OF THE SIL CATION-EFFLUX SYSTEM THAT CONFERS RESISTANCE TO SILVER. MAY BE PART OF A THREE-COMPONENT CATION/PROTON ANTIPORTER.; High confidence in function and specificity; cation efflux transmembrane protein	3240279..3241874	Azoarcus sp. BH72	4607706
YP_934458.1	CDS	azo2955	NC_008702.1	3242221	3246132	D	Region start changed from 3242195 to 3242423 (-228 bases); putative cation efflux system protein	3242221..3246132	Azoarcus sp. BH72	4608543
YP_934459.1	CDS	azo2956	NC_008702.1	3246273	3248684	D	Similar to E.coli CopA: copper transporting P-type ATPase protein, involved in the uptake and metabolism of copper(EC 3.6.3.4).Involved in copper transport(By similarity). Putative cation transporting P-type ATPase (EC 3.6.3.-).; High confidence in function and specificity; putative cooper-transporting ATPase	3246273..3248684	Azoarcus sp. BH72	4607707
YP_934460.1	CDS	azo2957	NC_008702.1	3248752	3249315	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs. HTH predicted; hypothetical protein	3248752..3249315	Azoarcus sp. BH72	4607708
YP_934461.1	CDS	azo2958	NC_008702.1	3249338	3249823	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3249338..3249823)	Azoarcus sp. BH72	4607709
YP_934462.1	CDS	azo2959	NC_008702.1	3250037	3250312	D	Carboxymuconolactone decarboxylase family protein,33% identity to TrEMBL;Q88K69. Has PF02627,Carboxymuconolactone decarboxylase family; Carboxymuconolactone decarboxylase (CMD)is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins (e.g. O67982) CMD represents the C-terminal domain,Abhydrolase_1 represents the N-terminal domain.; Function unclear; 4-carboxymuconolactone decarboxylase	3250037..3250312	Azoarcus sp. BH72	4607710
YP_934463.1	CDS	azo2960	NC_008702.1	3250526	3251743	D	27% similarity to Hypothetical protein ycxA (ORF5)of Bacillus subtilis. 12 predicted transmembrane helices with signal peptide. 54% identity, 69% similarity to Pseudomonas putida membrane protein. InterPro: General substrate transporters 2A0111: Oxalate/Formate Antiporter; Function unclear; putative transporter	3250526..3251743	Azoarcus sp. BH72	4607711
YP_934464.1	CDS	azo2961	NC_008702.1	3251743	3251892	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has Signal peptide; hypothetical protein	3251743..3251892	Azoarcus sp. BH72	4607712
YP_934465.1	CDS	sigZ	NC_008702.1	3251919	3252485	D	Putative RNA polymerase sigma factor sigZ. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|SIGZ_BACSU (23% Bacillus subtilis, RNA polymerase sigma factor SigZ) / sprot|RPSH_PSEAE (28% Pseudomonas aeruginosa, RNA polymerase sigma-h factor (sigma-30), AlgU or AlgT) InterPro: IPR000838 Sigma70_ECF. Pfam: PF07638 ECF sigma factor.; High confidence in function and specificity; putative RNA polymerase sigma factor SigZ	3251919..3252485	Azoarcus sp. BH72	4607713
YP_934466.1	CDS	chrA	NC_008702.1	3252493	3253860	R	Probable chromate transport protein.This protein reduces chromate accumulation and is essential for chromate resistance.Integral membrane protein.Induced by chromate. 27% Chromate_transpt. Pfam:PF02417; Chromate_transp; 2. TIGRFAMs:TIGR00937; 2A51; 1. TMHelix: 11. InterPro: Chromat transporter 2A51: Chromate Ion Transporter; High confidence in function and specificity; putative chromate transport protein	complement(3252493..3253860)	Azoarcus sp. BH72	4609870
YP_934467.1	CDS	chrB	NC_008702.1	3253862	3254782	R	Probable Chromate resistance signal peptide protein, 49% Identity to TrEMBL; Q7NZK1, Q8XSC4. Has Signal Pepride.; chromate resistance signal peptide protein	complement(3253862..3254782)	Azoarcus sp. BH72	4608480
YP_934468.1	CDS	azo2965	NC_008702.1	3254885	3255571	R	Protein yhhW. SPROT:P46852: 51% identity, 69% similarity entry represents N-terminal domain of Pirin proteins from both eukaryotes and prokaryotes. The function of Pirin is unknown but the gene coding for this protein is known to be expressed in all tissues in the human body InterPro; IPR007113; Cupin_sup. InterPro; IPR003829; Pirin_N. Pfam; PF02678; Pirin; TIGR00292: thiazole biosynthesis enzyme Absence of transmembrane helices (TMHMM predicted).; Function unclear; hypothetical protein	complement(3254885..3255571)	Azoarcus sp. BH72	4608481
YP_934469.1	CDS	azo2966	NC_008702.1	3255634	3256128	R	Conserved hypothetical membrane protein. Homology to VPA0043 of Vibrio parahaemolyticus of 64% (trembl|Q87K55). Pfam: TQO small subunit DoxD. DoxD is a subunit of the terminal quinol oxidase present in the plasma membrane of Acidianus ambivalens, with calculated molecular mass of 20.4 kDa. Thiosulphate:quinone oxidoreductase (TQO) is one of the early steps in elemental sulphur oxidation. A novel TQO enzyme was purified from the thermo-acidophilic archaeon Acidianus ambivalens and shown to consist of a large subunit (DoxD) and a smaller subunit (DoxA). The DoxD- and DoxA-like two subunits are fused together in a single polypeptide. Signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3255634..3256128)	Azoarcus sp. BH72	4607714
YP_934470.1	CDS	hupR	NC_008702.1	3256251	3257171	D	Transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	3256251..3257171	Azoarcus sp. BH72	4607715
YP_934471.1	CDS	wrbA1	NC_008702.1	3257288	3257887	D	SPROT:Q92PU3: 71% identity; 82% similarity Flavoprotein wrbA1. cofactor:binds 1 fmn per monomer (by similarity). similarity:belongs to the wrba family; contains 1 flavodoxin-like domain. InterPro:IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam: PF00258; flavodoxin; 1. Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) met_pdase_I: methionine aminopeptidase t; High confidence in function and specificity; trp repressor binding protein	3257288..3257887	Azoarcus sp. BH72	4609052
YP_934472.1	CDS	azo2969	NC_008702.1	3258728	3259585	R	Conserved hypothetical secreted protein. Homology to ebA582 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA582(KEGG)). No domains predicted. Signal P reporting signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(3258728..3259585)	Azoarcus sp. BH72	4610112
YP_934473.1	CDS	uvrY	NC_008702.1	3259643	3260290	R	Probable two-component response regulator,; Family membership; two-component response regulator	complement(3259643..3260290)	Azoarcus sp. BH72	4607716
YP_934474.1	CDS	azo2971	NC_008702.1	3260287	3261633	R	Putative two-component sensor histidine kinase,only very low similarity to SWISSPROT: sprot|DEGS_BACBR (13% Bacillus brevis, DegS) InterPro: IPR003661 His_kinA_N. Pfam: PF00672 HAMP domain. PF02518 Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase TMHMM reporting 2 transmembrane helices. Sensor protein degS (EC 2.7.3.-). INVOLVED IN A SENSORY TRANSDUCTION PATHWAY THAT AFFECT THE PRODUCTION OF ENZYMES THAT DEGRADE POLYMERIC CARBON AND NITROGEN SOURCES. DEGS PROBABLY ACTS AS A KINASE THAT PHOSPHORYLATES DEGU.; Function unclear; putative two-component sensor histidine kinase	complement(3260287..3261633)	Azoarcus sp. BH72	4610085
YP_934475.1	CDS	exaA2	NC_008702.1	3261821	3263698	D	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 73% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity; ExaA2 protein	3261821..3263698	Azoarcus sp. BH72	4607717
YP_934476.1	CDS	azo2973	NC_008702.1	3263828	3264388	D	Pentapeptide repeat family protein, 36% identity(46% similarity) to TrEMBL;Q88JH6. Signal P reporting Signal Peptide present. Has 3 copies of PF00805,Pentapeptide repeats;IPR001646, 5peptide_repeat;These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix . The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.; Conserved hypothetical protein; pentapeptide repeat-containing protein	3263828..3264388	Azoarcus sp. BH72	4608690
YP_934477.1	CDS	exaB2	NC_008702.1	3264394	3264876	D	Putative cytochrome c550. Homology to exaB of P. aeruginosa of 37% (trembl|Q9Z4P8). Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation. InterPro: Cytochrome c class I (IPR003088) Pfam: cytochrome c signal peptide no TMHs; Function unclear; putative cytochrome c550	3264394..3264876	Azoarcus sp. BH72	4607718
YP_934478.1	CDS	exaA3	NC_008702.1	3265163	3266950	R	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 53% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. TMhelix:1; High confidence in function and specificity; putative quinoprotein ethanol dehydrogenase	complement(3265163..3266950)	Azoarcus sp. BH72	4608695
YP_934479.1	CDS	azo2976	NC_008702.1	3267279	3268091	D	Conserved hypothetical secreted protein. Homology to PP2677 of P. putida of 35% (trembl|Q88JH2(SRS)). No domains predicted. Signal peptide present. No TMH detected.; Conserved hypothetical protein; hypothetical protein	3267279..3268091	Azoarcus sp. BH72	4608691
YP_934480.1	CDS	cphA	NC_008702.1	3268088	3269080	D	Conserved Hypothetical protein (pir:H95862; 47% identity ), putative hydrolase (TREMBL: Q88JH1; 54% identity, 66% similarity) putative cyclase (TREMBL: Q93IZ0) putative alkylsufatase/betalactamase (rba:RB11502) Metallo beta lactamase superfamily (Pfam) Signal P; TMHMM reporting transmembrane helices S18: ribosomal protein S18; High confidence in function and specificity; putative beta lactamase	3268088..3269080	Azoarcus sp. BH72	4607719
YP_934481.1	CDS	azo2978	NC_008702.1	3269103	3271517	D	Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. Probable tonB-dependent receptor yncD precursor. InterPro: TonB-dependent receptor protein.; High confidence in function and specificity; putative TonB-dependent receptor	3269103..3271517	Azoarcus sp. BH72	4608528
YP_934482.1	CDS	elmS	NC_008702.1	3271523	3272992	D	Putative two-component sensor histidine kinase,; Specificity unclear; putative two-component sensor histidine kinase	3271523..3272992	Azoarcus sp. BH72	4607720
YP_934483.1	CDS	gacA	NC_008702.1	3273206	3273850	D	Probable transcriptional regulator, LuxR family,; Specificity unclear; LuxR family transcriptional regulator	3273206..3273850	Azoarcus sp. BH72	4608665
YP_934484.1	CDS	azo2981	NC_008702.1	3274283	3276310	D	Putative methyl-accepting chemotaxis protein,; Conserved hypothetical protein; putative methyl-accepting chemotaxis protein	3274283..3276310	Azoarcus sp. BH72	4608853
YP_934485.1	CDS	azo2982	NC_008702.1	3276637	3276912	R	Conserved hypothetical protein. Homology to an orf of M. magnetotacticum of 33% (ZP_00053175). No domains predicted. No TMHs. No signal peptide; hypothetical protein	complement(3276637..3276912)	Azoarcus sp. BH72	4607721
YP_934486.1	CDS	azo2983	NC_008702.1	3277196	3278320	R	Putative Transposase,38% identity(55% similarity)to TrEMBL;Q877R1, Putative receptor protein (Transposase) [BT1893] [Bacteroides thetaiotaomicron VPI-5482]. Has PF01609:Transposase DDE domain;Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4 P03835, IS421 P11901, IS5377 Q45620, IS427 , IS402, IS1355 O69604, IS5,which was original isolated in bacteriophage lambda. IPR002559:Transposase_11. GO:0004872;Molecular function: receptor activity. Signal peptide present. NO TMH reported present.; Family membership; putative transposase	complement(3277196..3278320)	Azoarcus sp. BH72	4607722
YP_934487.1	CDS	azo2984	NC_008702.1	3278702	3279538	D	Hypothetical secreted protein. no homology to the data bank. Pfam: DUF1555. signal peptide. TMH in signal peptide; hypothetical protein	3278702..3279538	Azoarcus sp. BH72	4607723
YP_934488.1	CDS	tnkS	NC_008702.1	3279788	3280681	D	Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein). May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1 and thereby contribute to the regulation of telomere length. TREMBL:Q800E0:34%; Q8YTG9:36% identity. InterPro: Ankyrin-repeat Mop: molybdenum-pterin binding domain Presence of signal peptide (SignalP) but absence of transmembrane helices; Function unclear; putative tankyrase type protein	3279788..3280681	Azoarcus sp. BH72	4607724
YP_934489.1	CDS	azo2986	NC_008702.1	3280842	3281492	R	Similar to TREMBL:Q82SQ0 (50% identity ,67% similarity).; Function unclear; putative methyltransferase	complement(3280842..3281492)	Azoarcus sp. BH72	4609955
YP_934490.1	CDS	azo2987	NC_008702.1	3281489	3282034	R	Putative Dihydrofolate reductase.; Function unclear; dihydrofolate reductase	complement(3281489..3282034)	Azoarcus sp. BH72	4607725
YP_934491.1	CDS	chrR	NC_008702.1	3282330	3282890	R	Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity; chromate reductase	complement(3282330..3282890)	Azoarcus sp. BH72	4607726
YP_934492.1	CDS	katG	NC_008702.1	3283201	3285402	D	Peroxidase/catalase (EC 1.11.1.6). Bifunctional exhibiting both a catalase and broad- spectrum peroxidase activities.Peroxidases are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions.Bacterial catalase-peroxidases are approximately twice the size of plant and fungal haem peroxidases. Sequence analysis suggests that this doubling in length can be ascribed to gene duplication, whereby each half is; High confidence in function and specificity; putative catalase/peroxidase	3283201..3285402	Azoarcus sp. BH72	4608482
YP_934493.1	CDS	azo2990	NC_008702.1	3285452	3286078	R	Similar to TREMBL:Q88PY7 (90% identity); SWISSPROT:P21367 (87% identity); TREMBL:Q7W0U0 (85% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Specificity unclear; putative isochorismatase	complement(3285452..3286078)	Azoarcus sp. BH72	4609099
YP_934494.1	CDS	azo2991	NC_008702.1	3286186	3287082	R	Hypothetical protein PA2418. Pirin related protein of unknown function. TREMBL:Q7VUX8: 69% identity, 81% similarity. InterPro:IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam: PF02678; Pirin; 1. PF05726; Pirin_C InterPro: DUF209 No signal peptide present (Signal P predicted). No transmembrane helices present (TMHMM predicted). hypD: hydrogenase expression/formation pr; Specificity unclear; hypothetical protein	complement(3286186..3287082)	Azoarcus sp. BH72	4607727
YP_934495.1	CDS	azo2992	NC_008702.1	3287206	3288111	D	Probable transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	3287206..3288111	Azoarcus sp. BH72	4607728
YP_934496.1	CDS	azo2993	NC_008702.1	3288180	3288830	D	DNA-binding protein or Dihydrofolat-Reductase ???; Function unclear; DNA-binding protein	3288180..3288830	Azoarcus sp. BH72	4607729
YP_934497.1	CDS	fpvA2	NC_008702.1	3288843	3291056	R	Iron-regulated outer membrane protein. TonB-dependent receptor protein. Homolog to fpvA, a ferripyoverdine receptor precursor in P. aeruginosa. Similar to PupA protein of P. putida WCS,this protein is a receptor for the iron-bound form of pesudobactin, a compound structurally very; High confidence in function and specificity; TonB-dependent receptor	complement(3288843..3291056)	Azoarcus sp. BH72	4607730
YP_934498.1	CDS	azo2995	NC_008702.1	3291403	3291858	R	Conserved hypothetical membrane protein. Homology to IL2513 of Idiomarina loihiensis of 37% (gnl|keqq|ilo:IL2513(KEGG)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	complement(3291403..3291858)	Azoarcus sp. BH72	4608828
YP_934499.1	CDS	azo2996	NC_008702.1	3291855	3293027	R	Conserved hypothetical membrane protein. Homology to PA2403 of Pseudomonas aeruginosa of 38% (trembl|Q8G8F6). Has 3 copies of PF03929, PepSY-associated TM helix;IPR005625 pEPsy_tm; This domain represents a conserved TM helix found in bacterial proteins. Has PF03413, Peptidase propeptide and YPEB domain; IPR005075,Propep_PepSY:This region is likely to have an protease inhibitory function (personal obs:C Yeats). This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB. no signal peptide. 4TMHs; Conserved hypothetical protein; hypothetical protein	complement(3291855..3293027)	Azoarcus sp. BH72	4607731
YP_934500.1	CDS	fhuF	NC_008702.1	3293030	3295177	R	Ferrioxamine B receptor precursor, FhuF. Iron-regulated outer membrane protein that bind and uptake ferrioxamine in association with the TonB protein. Involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. Binds 1 2Fe-2S cluster. In e.coli the fhuF gene reacts very sensitive to minor changes of Fe2+ and Fur(Ferric uptake regulator). SWISSPROT: FOXA_SALTY. Prim. accession #:Q56145 EMBL: AE008712; AAL19318.1; AF060876; AAC15464.1; U62282; AAB04552.1; InterPro:IPR000531; TonB_boxC. Pfam: PF00593; TonB_dep_Rec; 1. PROSITE: PS00430; TONB_DEPENDENT_REC_1; FALSE_NEG. PS01156; TONB_DEPENDENT_REC_2; FALSE_NEG.; High confidence in function and specificity; putative TonB-dependent receptor	complement(3293030..3295177)	Azoarcus sp. BH72	4607732
YP_934501.1	CDS	azo2998	NC_008702.1	3295639	3296769	D	Hypothetical protein predicted by Glimmer/Critica. InterPro: Esterase/lipase/thioesterase family active site (IPR000379), GCN5-realted N-actetyltransferase (IPR000182). no signal peptide. no TMHs; hypothetical protein	3295639..3296769	Azoarcus sp. BH72	4608762
YP_934502.1	CDS	azo2999	NC_008702.1	3296777	3297358	R	Conserved hypothetical secreted protein. Homology to NE2572 of N.europaea of 46% (tremble:Q82RZ3). Has PF05951, Bacterial protein of unknown function (DUF882);IPR010275; This family consists of a series of hypothetical bacterial proteins of unknown function. Signal Peptide Present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3296777..3297358)	Azoarcus sp. BH72	4607733
YP_934503.1	CDS	ycbB	NC_008702.1	3297392	3299023	R	Putative periplasmic protein [ycbB], 39% identity(57% similarity) to TrEMBL;Q82RZ2.Q9A853(30% identity) Signal Peptide Present. Has PF01471, Putative peptidoglycan binding domain; IPR002477 PG_binding; This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. * Muramoyl-pentapeptide carboxypeptidase (EC:3.4.17.8) * N-acetylmuramoyl-L-alanine amidase cwlA precursor (cell wall) hydrolase, autolysin, EC:3.5.1.28) * Autolytic lysozyme (1,4--N-acetylmuramidase, autolysin, EC:3.2.1.17) * Membrane-bound lytic murein transglycosylase B; Family membership; hypothetical protein	complement(3297392..3299023)	Azoarcus sp. BH72	4607734
YP_934504.1	CDS	azo3001	NC_008702.1	3299083	3300033	R	Conserved hypothetical membrane protein. Homology to XAC149 of X. axonopodis of 41% (trembl|Q8PLP4(SRS)). Pfam: DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions. no signal peptide. 4 TMHs.; Conserved hypothetical protein; hypothetical protein	complement(3299083..3300033)	Azoarcus sp. BH72	4610153
YP_934505.1	CDS	hutG	NC_008702.1	3300159	3300980	R	Conserved hypothetical formylglutamte amindohyrolase. Homology to hutG of B. bronchiseptica of 53% (trembl|Q7WEA2). Catalyses the terminal reaction in the five-step pathway for histidine utilisation. no signal peptide. no TMHs; Conserved hypothetical protein; formylglutamte aminohyrolase	complement(3300159..3300980)	Azoarcus sp. BH72	4607735
YP_934506.1	CDS	azo3003	NC_008702.1	3300977	3302122	R	Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; Family membership; hypothetical protein	complement(3300977..3302122)	Azoarcus sp. BH72	4609054
YP_934507.1	CDS	soxB	NC_008702.1	3302210	3303394	D	Sarcosine oxidase, subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q82M71 (29%) and to trembl|Q9V0K7 (26%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site ProSite (PS50204): UBA/THIF-type NAD/FAD binding fold; Specificity unclear; putative sarcosine oxidase subunit beta	3302210..3303394	Azoarcus sp. BH72	4607736
YP_934508.1	CDS	etfB4	NC_008702.1	3303449	3304201	D	Probable electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 54% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein beta-subunit (IPR000049) Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity; electron transfer flavoprotein subunit beta	3303449..3304201	Azoarcus sp. BH72	4609881
YP_934509.1	CDS	etfA4	NC_008702.1	3304218	3305165	D	Probable electron transfer flavoprotein, alpha subunit. Homology to etfA of B. japonicum of 49% (sprot|ETFA_BRAJA) The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). InterPro: Electron transfer flavoprotein alpha-subunit (IPR001308) Pfam: Electron transfer flavoprotein alpha subunit no signal peptide no TMHs; High confidence in function and specificity; electron transfer flavoprotein subunit alpha	3304218..3305165	Azoarcus sp. BH72	4608685
YP_934510.1	CDS	azo3007	NC_008702.1	3305177	3305785	D	Conserved hypothetical protein. Homology to BB1278 of B.bronchiseptica of 35% (trembl:Q7WMW2). Has PF05962,Bacterial protein of unknown function (DUF886);IPR010282; This family consists of several hypothetical bacterial proteins of unknown function. No signal peptide or TMH present.; hypothetical protein	3305177..3305785	Azoarcus sp. BH72	4608681
YP_934511.1	CDS	etf2	NC_008702.1	3305802	3307487	D	Probable electron transfer flavoprotein-ubiquinone oxidoreductase. Homology to etfdh of H. sapiens of 53% (sprot|ETFD_HUMAN) Accepts electrons and reduces ubiquinone. Pfam: FAD_binding_3; ETF_QO no signal peptide no TMHs; High confidence in function and specificity; electron transfer flavoprotein-ubiquinone oxidoreductase	3305802..3307487	Azoarcus sp. BH72	4607737
YP_934512.1	CDS	azo3009	NC_008702.1	3307684	3308286	R	Putative DNA binding helix-turn helix protein,; Family membership; putative DNA binding helix-turn helix protein	complement(3307684..3308286)	Azoarcus sp. BH72	4608677
YP_934513.1	CDS	glnT	NC_008702.1	3308451	3309848	D	Glutamine synthetase III plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to trembl|Q98A06 (58%) and to sprot|GLN3_RHILP (38%). Pfam (PF03951): Glutamine synthetase, beta-Grasp domain Pfam(PF00120): Glutamine synthetase, catalytic domain; High confidence in function and specificity; glutamine synthetase	3308451..3309848	Azoarcus sp. BH72	4607738
YP_934514.1	CDS	glxB	NC_008702.1	3309864	3310772	D	Glutamine amidotransferase, class-II protein, glxB (purF). Similar to sprot|GLXB_RHIME (46%) and to trembl|Q882P3 (49%). Glutamine amidotransferase catalyse the removal of the ammonia group from glutamine and then to transfer this group to a substrate to form a new carbon-nitrogen group. This catalytic activity is known as glutamine amidotransferase (GATase). On the basis of sequence similarities two classes of GATase domains have been identified class-I and class-II (also known as purF-type). Enzymes containing Class-II GATase domains include amido phosphoribosyltransferase, which catalyses the first step in purine biosynthesis. InterPro (PF00310): Glutamine amidotransferase class-II; High confidence in function and specificity; amido phosphoribosyltransferase	3309864..3310772	Azoarcus sp. BH72	4608905
YP_934515.1	CDS	glxC	NC_008702.1	3310760	3311452	D	Probable protein GlxC. Similar to sprot|GLXC_RHIME (59%) and to pir|A96211 (51%). Pfam (PF01493): GXGXG; Family membership; protein GlxC	3310760..3311452	Azoarcus sp. BH72	4608919
YP_934516.1	CDS	glxD	NC_008702.1	3311454	3312797	D	Glutamate synthase, large subunit. Similar to sprot|GLXD_RHIME (87%). Glutamate synthase (GltS) is a complex iron-sulphur flavoprotein that catalyses the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the bacterial, yeast and plant pathways for ammonia assimilation. Pfam: Conserved region in glutamate synthase; Specificity unclear; glutamate synthase large subunit	3311454..3312797	Azoarcus sp. BH72	4608920
YP_934517.1	CDS	glnY	NC_008702.1	3312866	3313204	D	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ4 (100%) and to trembl|Q9RBK0 (78%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity; PII-like signal transmitter protein GlnY	3312866..3313204	Azoarcus sp. BH72	4608921
YP_934518.1	CDS	amtY	NC_008702.1	3313222	3314586	D	Ammonium transporter 1 member 2 (LeAMT1;2). Involved in high affinity ammonium uptake. TREMBL:Q8RP88: 100% identity (published) InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp amt: ammonium transporter SignalP predicted signal peptide (probability 0.999) TMHMM predicted 11 transmembrane helices; High confidence in function and specificity; ammonium transporter	3313222..3314586	Azoarcus sp. BH72	4608906
YP_934519.1	CDS	azo3016	NC_008702.1	3314644	3315441	R	Conserved hypothetical secreted protein. Homology to ECA3203 of Erwinia carotovora of 58% (tremble:Q6D293). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3314644..3315441)	Azoarcus sp. BH72	4608319
YP_934520.1	CDS	azo3017	NC_008702.1	3315684	3316808	R	Outer membrane porin protein 32 precursor (OMP32). Forms anion selective channels.; Specificity unclear; outer membrane porin protein	complement(3315684..3316808)	Azoarcus sp. BH72	4607739
YP_934521.1	CDS	azo3018	NC_008702.1	3316976	3317098	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted .no signal peptide. no TMHs; hypothetical protein	complement(3316976..3317098)	Azoarcus sp. BH72	4607740
YP_934522.1	CDS	azo3019	NC_008702.1	3317346	3318281	D	Putative AraC family,transcriptional regulator, 28% Identity to TrEMBL;Q62GH5,Q6QEJ0,Q9HWT4 Has SMART;SM00342,HTH_ARAC, helix_turn_helix, arabinose operon control protein;IPR000005; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the arabinose operon regulatory protein AraC. Except for celD all of these proteins seem to be positive transcriptional factors.Although the sequences belonging to this family differ somewhat in length, in nearly every case the HTH motif is situated towards the C-terminus in the third quarter of most of the sequences. The minimal DNA binding domain spans roughly 100 residues and comprises two HTH subdomains; the classical HTH domain and another HTH subdomain with similarity to the classical HTH domain but with an insertion of one residue in the turn-region. The N-terminal and central regions of these proteins are presumed to interact with effector molecules and may be involved in dimerization.; Conserved hypothetical protein; putative AraC-like transcriptional regulator	3317346..3318281	Azoarcus sp. BH72	4607741
YP_934523.1	CDS	azo3020	NC_008702.1	3318463	3319443	D	Conserved hypothetical secreted protein. Homology to aciad2673 of Acinetobacter sp. of 53% (trembl|Q6F937). no domains reported. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	3318463..3319443	Azoarcus sp. BH72	4607742
YP_934524.1	CDS	thmS2	NC_008702.1	3319525	3320985	D	Probable succinate semialdehyde dehydrogenase [NAD(P)+]. Homology to thmS of Pseudonocardia sp. K1 of 46% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership; succinate semialdehyde dehydrogenase	3319525..3320985	Azoarcus sp. BH72	4607743
YP_934525.1	CDS	exaA4	NC_008702.1	3321256	3323430	D	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 37% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present.; High confidence in function and specificity; putative quinoprotein ethanol dehydrogenase	3321256..3323430	Azoarcus sp. BH72	4609942
YP_934526.1	CDS	azo3023	NC_008702.1	3323986	3326103	D	Probable outer membrane receptor TonB-dependent for iron transport. 41% AAC74533.1 InterPro: IPR000531 TonB_receptor.IPR010105; TonB_siderophor. Pfam: PF00593; TonB_dep_Rec; 1. TonB-box domain; High confidence in function and specificity; TonB-dependent receptor	3323986..3326103	Azoarcus sp. BH72	4608692
YP_934527.1	CDS	azo3024	NC_008702.1	3326109	3326648	D	Hypotheical secreted protein. No homology of the entire protein to the data bank. no domains predicted. no TMHs. signal peptide.; hypothetical protein	3326109..3326648	Azoarcus sp. BH72	4607744
YP_934528.1	CDS	azo3025	NC_008702.1	3326814	3327098	D	Conserved hypothetical protein. Homology to ra0176 of S. meliloti of 31% (trembl|Q930L9). Pfam: Uncharacterized ACR, YneC family. no signal peptide. no TMHS; hypothetical protein	3326814..3327098	Azoarcus sp. BH72	4607745
YP_934529.1	CDS	azo3026	NC_008702.1	3327420	3329078	D	Conserved hypothetical secreted protein. Homology to Reut02004453 of Ralstonia metallidurans of 38% (gi|48768314|ref|ZP_00272664.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs.; Conserved hypothetical protein; hypothetical protein	3327420..3329078	Azoarcus sp. BH72	4607746
YP_934530.1	CDS	azo3027	NC_008702.1	3329161	3329490	D	Conserved hypothetical secreted protein. Homology to RS04458 of Ralstonia solanacearum of 31% (tremble:Q8Y292). No domains predicted .Signal peptide reported. NO TMH present.; Conserved hypothetical protein; hypothetical protein	3329161..3329490	Azoarcus sp. BH72	4607747
YP_934531.1	CDS	azo3028	NC_008702.1	3329491	3330198	D	Conserved hypothetical peptidase. Homology to rsc0445 of R. solanacearum of 50% (trembl|Q8Y291). Pfam: Peptidas_C39. Lantibiotic and non-lantibiotic bacteriocins are synthesised as precursor peptides containing N-terminal extensions (leader peptides) which are cleaved off during maturation. Most non-lantibiotics and also some lantibiotics have leader peptides of the so-called double-glycine type. These leader peptides share consensus sequences and also a common processing site with two conserved glycine residues in positions -1 and -2. The double- glycine-type leader peptides are unrelated to the N-terminal signal sequences which direct proteins across the cytoplasmic membrane via the sec pathway. Their processing sites are also different from typical signal peptidase cleavage sites, suggesting that a different processing enzyme is involved. signal peptide. no TMHs; Conserved hypothetical protein; peptidase	3329491..3330198	Azoarcus sp. BH72	4607748
YP_934532.1	CDS	azo3029	NC_008702.1	3330212	3331177	D	Hypothetical secreted protein. No good homology over the entire length in DB. No domains predicted. Signal Peptide present. No TMH present.; hypothetical protein	3330212..3331177	Azoarcus sp. BH72	4607749
YP_934533.1	CDS	azo3030	NC_008702.1	3331211	3332539	R	Conserved hypothetical secreted protein. Homology to RS04455 of R.solanacearum of 50% (tremble:Q8Y289). No domains predicted. Signal P reporting signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(3331211..3332539)	Azoarcus sp. BH72	4607750
YP_934534.1	CDS	azo3031	NC_008702.1	3332594	3333922	R	Probable transcriptional regulatory protein,; Specificity unclear; transcriptional regulator	complement(3332594..3333922)	Azoarcus sp. BH72	4607751
YP_934535.1	CDS	azo3032	NC_008702.1	3334477	3334860	D	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. TMH in signal peptide.; hypothetical protein	3334477..3334860	Azoarcus sp. BH72	4607752
YP_934536.1	CDS	azo3033	NC_008702.1	3334857	3334991	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	3334857..3334991	Azoarcus sp. BH72	4607753
YP_934537.1	CDS	azo3034	NC_008702.1	3335002	3335409	D	Hypothetical membrane protein. no homology to the data bank. no domains predicted. no signal peptide. 3 TMHs; hypothetical protein	3335002..3335409	Azoarcus sp. BH72	4607754
YP_934538.1	CDS	azo3035	NC_008702.1	3335418	3336713	D	Hypothetical membrane protein. no homology to the data bank. no domains predicted. signal peptide. 2 TMHs; hypothetical protein	3335418..3336713	Azoarcus sp. BH72	4607755
YP_934539.1	CDS	azo3036	NC_008702.1	3336852	3337970	R	Conserved hypothetical protein. Homology to Rgel02002356 of Rubrivivax gelatinosus of 47% (gi|47573226|ref|ZP_00243265.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(3336852..3337970)	Azoarcus sp. BH72	4607756
YP_934540.1	CDS	azo3037	NC_008702.1	3337939	3338643	R	conserved hypothetical protein. Homology to Rgel02002355 of Rubrivivax gelatinosus of 41% (gi|47573225|ref|ZP_00243264.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(3337939..3338643)	Azoarcus sp. BH72	4607757
YP_934541.1	CDS	fdhA1	NC_008702.1	3339274	3342159	R	Probable formate dehydrogenase (NADP+), alpha subunit. Homology to fdh1A of M. extorquens of 60% (trembl|Q8KTI7). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655); Respiratory-chain NADH dehydrogenase 75 kD subunit (IPR000283); Ferredoxin (IPR001041); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Pfam: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-2S binding doami; Molybdopterin oxidase; Molybdopterin dinucloetide binding no signal peptide no TMHs; High confidence in function and specificity; formate dehydrogenase subunit alpha	complement(3339274..3342159)	Azoarcus sp. BH72	4607758
YP_934542.1	CDS	fdh1B	NC_008702.1	3342156	3343871	R	Probable formate dehydrogenase (NADP+), beta subunit Homology to fdh1B of M. extorpuens of 55% (trembl|Q8KTI8) Pfam: Respiratory-chain NADH dehydrogenase 24 kD subunit; Respiratory-chain NADH dehydrogenase 51 kD subunit. no signal peptide no TMHs; High confidence in function and specificity; formate dehydrogenase (NADP+) subunit beta	complement(3342156..3343871)	Azoarcus sp. BH72	4608740
YP_934543.1	CDS	paaH2	NC_008702.1	3344244	3345770	R	converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase	complement(3344244..3345770)	Azoarcus sp. BH72	4608739
YP_934544.1	CDS	rubA	NC_008702.1	3345835	3346002	R	Probable rubredoxin. Homology to ruba of A. calcoaceticus of 42% (sprot|RUBR_ACIAD). Involved in the hydrocarbon hydroxylating system to convert dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. Pfam: Rubredoxin no singal peptide no TMHs; Family membership; rubredoxin	complement(3345835..3346002)	Azoarcus sp. BH72	4609479
YP_934545.1	CDS	azo3042	NC_008702.1	3346059	3347039	R	ZP_00167050: 52% identity; 70% similarity. Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta- crystallin). DOES NOT HAVE ALCOHOL DEHYDROGENASE ACTIVITY. BINDS NADP AND ACTS THROUGH A ONE-ELECTRON TRANSFER PROCESS. ORTHOQUINONES ARE THE BEST SUBSTRATES. MAY ACT IN THE DETOXIFICATION OF XENOBIOTICS (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N TIGRFAM: 2A0302: arginine/ornithine antiporter tdh: L-threonine 3-dehydrogenase; Function unclear; NADPH quinone oxidoreductase	complement(3346059..3347039)	Azoarcus sp. BH72	4609832
YP_934546.1	CDS	paaG4	NC_008702.1	3347056	3347859	R	COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). catalytic activity:-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl- coa + H(2)o. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 72/262 (27%) Number of predicted TMHs: 0; Family membership; enoyl-CoA hydratase	complement(3347056..3347859)	Azoarcus sp. BH72	4607759
YP_934547.1	CDS	ybgC	NC_008702.1	3347868	3348293	R	Hypothetical protein HI0386. TREMBL:Q84HI6: 48% identity, 66% similarity 4-hydroxybenzoyl-CoA thioesterase is a protein of 141 amino-acid residues that assemble as an homotetramer. An aspartate in the N-terminal domain is thought to participate in the catalytic mechanism 4-hydroxybenzoyl-CoA + H2 O = 4-hydroxybenzoate + CoA IPR006683; Thioesterase superfamily IPR006684; 4-hydroxybenzoyl-CoA thioesterase Pfam:PF03061; 4HBT; No transmembrane helices (TMHMM predicted) TIGR00051: conserved hypothetical protein; High confidence in function and specificity; thioesterase	complement(3347868..3348293)	Azoarcus sp. BH72	4609475
YP_934548.1	CDS	azo3045	NC_008702.1	3348797	3349570	R	TREMBL:Q84HI5: 83% identity, 89% similarity from Azoarcus evansii (gene name refereed as ORF2) Haloalkane dehalogenase (EC 3.8.1.5). Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds leading to the formation of the corresponding primary alcohols halide ions and protons. Has a broad substrate specificity which includes mono- and di- chlorinated and brominated alkanes. The highest activity was found with 12-dibromoethane whereas low activity was measured with the analog 12-dichloroethane. InterPro: Alpha/beta hydrolase fold Description:lactonase. InterPro:IPR000379; Ser_estrs Pfam:abhydrolase_2, Thioesterase aroC: chorismate synthase Signal P predicted nonsecretiory protein without transmembrane helices.; High confidence in function and specificity; lactonase	complement(3348797..3349570)	Azoarcus sp. BH72	4610148
YP_934549.1	CDS	azo3046	NC_008702.1	3349583	3350377	R	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI4 (80%) and to trembl|Q89VH8 (45%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; ABC transporter ATP-binding protein	complement(3349583..3350377)	Azoarcus sp. BH72	4607760
YP_934550.1	CDS	livG1	NC_008702.1	3350370	3351176	R	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q84HI3 (79%) and to sprot|LIVG_ECOLI (37%). Pfam (PF00005): ABC transporter ProSite (PS50101): ATP/GTP-binding site motif A (P-loop) Smart (SM00382): AAA ATPase superfamily; Specificity unclear; ABC transporter ATP-binding protein	complement(3350370..3351176)	Azoarcus sp. BH72	4607761
YP_934551.1	CDS	livM3	NC_008702.1	3351169	3352149	R	Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 31% as well as genes coding for a new pathway of aerobic benzoate meabolisme in A. evansii (77%). Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system. probable signal peptide probable 8 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	complement(3351169..3352149)	Azoarcus sp. BH72	4609149
YP_934552.1	CDS	azo3049	NC_008702.1	3352156	3353022	R	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q84HI2 (91%), to trembl|Q89VI1 (47%), to sprot|LIVH_ECOLI (27%) and to sprot|BRAD_PSEAE (30%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting six Tmhelix.; Specificity unclear; ABC transporter permease	complement(3352156..3353022)	Azoarcus sp. BH72	4609160
YP_934553.1	CDS	livJ	NC_008702.1	3353237	3354418	R	In enteric bacteria such E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar trembl|Q93FB9 (84%) and to sprot|LIVJ_ECOLI (21%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF04392): Protein of unknown function (DUF534) SignalP reporting Signal peptide.; Specificity unclear; putative leucine-specific binding protein	complement(3353237..3354418)	Azoarcus sp. BH72	4607762
YP_934554.1	CDS	azo3051	NC_008702.1	3354486	3354983	R	Conserved hypothetical protein. Homology Daro03002253 of Dechloromonas aromatica of 43% (gi|53730397|ref|ZP_00151095.2|(NBCI ENTREZ)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No TMHs. No signal peptide.; hypothetical protein	complement(3354486..3354983)	Azoarcus sp. BH72	4609152
YP_934555.1	CDS	bzdA	NC_008702.1	3354997	3356595	R	Entry name :- TREMBL:Q84HI0 Entry name :-TREMBL:Q8VUF1 InterPro IPR010071; AA_adenyl_dom. IPR000873; AMP-bind. IPR010192; MenE. Pfam PF00501; AMP-binding; 1 Identities = 414/532 (77%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; benzoate-coa ligase	complement(3354997..3356595)	Azoarcus sp. BH72	4607763
YP_934556.1	CDS	azo3053	NC_008702.1	3356689	3357153	R	Conserved hypothetical protein. Homology to an orf of A. evnasii of 79% (trembl|Q84HH9). no domains predicted. no signal peptide. no TMHS; hypothetical protein	complement(3356689..3357153)	Azoarcus sp. BH72	4608408
YP_934557.1	CDS	azo3054	NC_008702.1	3357353	3358930	R	Aldehyde dehydrogenase (NAD+). Homology to the aldehyce dehydrogenase of the of the benzoate gene cluster of A. evansii of 81% (trembl|Q84HH8). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Here clustered with genes involved in the aerobic benzoate metabolism. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity; aldehyde dehydrogenase	complement(3357353..3358930)	Azoarcus sp. BH72	4607764
YP_934558.1	CDS	azo3055	NC_008702.1	3359261	3360175	D	consists of N-terminal helix-turn-helix domain and C-terminal shikimate kinase-like domain which may bind benzoyl-CoA; controls inducible expression of the bzd catabolic operon that is involved in the anaerobic catabolism of benzoate; anaerobic benzoate catabolism transcriptional regulator	3359261..3360175	Azoarcus sp. BH72	4607765
YP_934559.1	CDS	azo3056	NC_008702.1	3360200	3361864	D	cleaves the ring of 2,3-dihydro-2,3-dihydroxybenzoyl-CoA forming 6-hydroxy-3-hexenoyl-CoA; benzoyl-CoA-dihydrodiol lyase	3360200..3361864	Azoarcus sp. BH72	4607766
YP_934560.1	CDS	boxB	NC_008702.1	3362066	3363490	D	Benzoyl-CoA oxygenase component B. 85%; Function unclear; benzoyl-CoA oxygenase component B	3362066..3363490	Azoarcus sp. BH72	4607767
YP_934561.1	CDS	boxA	NC_008702.1	3363690	3364940	D	Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1.; High confidence in function and specificity; putative benzoyl-CoA oxygenase component A	3363690..3364940	Azoarcus sp. BH72	4608402
YP_934562.1	CDS	azo3059	NC_008702.1	3365275	3366483	D	catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase	3365275..3366483	Azoarcus sp. BH72	4608401
YP_934563.1	CDS	azo3060	NC_008702.1	3366498	3367259	D	Conserved hypothetical protein. Homology to ebA2769 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA2769(KEGG)). Pfam: Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No TMHs. No signal peptide.; hypothetical protein	3366498..3367259	Azoarcus sp. BH72	4607768
YP_934564.1	CDS	azo3061	NC_008702.1	3367800	3370820	R	GGDEF/EAL/PAS/PAC/GAF-domain containing protein; diguanylate cyclase	complement(3367800..3370820)	Azoarcus sp. BH72	4607769
YP_934565.1	CDS	brkB	NC_008702.1	3371066	3372010	R	Putative Ribonuclease RNASE_BN Protein, 28% identity to TrEMBL;Q8XPH6. Has PF03631, Ribonuclease BN-like family;IPR004664, RNase_BN: This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Conserved hypothetical protein; exoribonuclease II	complement(3371066..3372010)	Azoarcus sp. BH72	4607770
YP_934566.1	CDS	azo3063	NC_008702.1	3372179	3373117	R	Conserved hypothetical membrane protein. Homology to CV2531 of C. violaceum of 37%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Tranporter. Pfam: Integral membrane protein DUF6. probable 10 TMHs. probable signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3372179..3373117)	Azoarcus sp. BH72	4608406
YP_934567.1	CDS	lrp1	NC_008702.1	3373359	3373826	D	Leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (40% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; leucine-responsive regulatory protein	3373359..3373826	Azoarcus sp. BH72	4607771
YP_934568.1	CDS	mvaB	NC_008702.1	3374096	3375016	R	Hydroxymethylglutaryl-CoA lyase, MvaB. It catalyses the conversion of (S)-3-hydroxy-3-methylglutaryl-CoA to acetyl-CoA and acetoacetate during the final step of ketogenesis and leucine catabolism. Similar to trembl|Q8QGJ4 (60%) and to pir|H83394 (56%). InterPro (PF00682): HMG-CoA Lyase-like family; High confidence in function and specificity; hydroxymethylglutaryl-CoA lyase	complement(3374096..3375016)	Azoarcus sp. BH72	4609180
YP_934569.1	CDS	fadD3	NC_008702.1	3375027	3376715	R	activates fatty acids by binding to coenzyme A; AMP-binding protein	complement(3375027..3376715)	Azoarcus sp. BH72	4609299
YP_934570.1	CDS	ycjD	NC_008702.1	3376848	3377219	R	Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr); hypothetical protein	complement(3376848..3377219)	Azoarcus sp. BH72	4608724
YP_934571.1	CDS	accC2	NC_008702.1	3377487	3379487	R	This protein is a component of the acetyl coenzyme a carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-coa. Entry name TREMBL:Q8PDU1 InterPro IPR001882; Biotin_BS. IPR005482; Biotin_carb_C. IPR000089; Biotin_lipoyl. IPR005479; CPase_L_D2. IPR005481; CPase_L_N. Pfam PF02785; Biotin_carb_C; 1. PF00364; Biotin_lipoyl; 1. PF00289; CPSase_L_chain; 1. PF02786; CPSase_L_D2; 1. Identities = 382/661 (57%) Preediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; biotin carboxylase	complement(3377487..3379487)	Azoarcus sp. BH72	4610162
YP_934572.1	CDS	paaG5	NC_008702.1	3379877	3380665	R	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase	complement(3379877..3380665)	Azoarcus sp. BH72	4608257
YP_934573.1	CDS	azo3070	NC_008702.1	3380677	3382284	R	Activity:- ATP + 3-methylcrotonoyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA Entry name:-TREMBL:Q7WDP0 InterPro:- IPR000022; Carboxyl_trans. Pfam:-PF01039; Carboxyl_trans; 1. Identities = 413/535 (77%) Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.098; Family membership; carboxyltransferase subunit of acetyl-CoA carboxylase	complement(3380677..3382284)	Azoarcus sp. BH72	4609476
YP_934574.1	CDS	azo3071	NC_008702.1	3382372	3382614	R	Region start changed from 3382650 to 3382614 (-36 bases), , Changed start codon from att to next gtg; hypothetical protein	complement(3382372..3382614)	Azoarcus sp. BH72	4607772
YP_934575.1	CDS	azo3072	NC_008702.1	3382666	3383205	R	hypothetical protein	complement(3382666..3383205)	Azoarcus sp. BH72	4607773
YP_934576.1	CDS	azo3073	NC_008702.1	3383307	3384761	R	Hypothetical protein. No homology to the data base. Pfam: Protein tyrosine kinase, Protein kinase domain. Interpro: IPR000719 Protein kinase, IPR002290 Serine/threonine protein kinase, IPR001245 Tyrosine protein kinase, IPR011009 Protein kinase-like. No signal peptide. No TMHs; hypothetical protein	complement(3383307..3384761)	Azoarcus sp. BH72	4607774
YP_934577.1	CDS	azo3074	NC_008702.1	3384762	3385667	R	hypothetical protein	complement(3384762..3385667)	Azoarcus sp. BH72	4607775
YP_934578.1	CDS	azo3075	NC_008702.1	3385767	3386345	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. signal peptide. 3 TMHs; hypothetical protein	complement(3385767..3386345)	Azoarcus sp. BH72	4607776
YP_934579.1	CDS	azo3076	NC_008702.1	3387069	3387359	D	Conserved hypothetical protein. Homology to TdenA01001814 of Thiobacillus denitrificans of 40% (gi|52006871|ref|ZP_00334250.1|(NBCI ENTREZ)). Has PF01402, Ribbon-helix-helix protein, copG family; IPR002145 HTH_CopG; The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected. No TMHs. No signal peptide.; hypothetical protein	3387069..3387359	Azoarcus sp. BH72	4607777
YP_934580.1	CDS	azo3077	NC_008702.1	3387356	3387649	D	Conserved hypothetical protein. Homology to xcc3092 of X. campestris of 51% (trembl|Q8P678). Pfam: Plasmid stabilisation system protein. Members of this family are involved in plasmid stabilisation. The exact molecular function of this protein is not known. no signal peptide. no TMHs; hypothetical protein	3387356..3387649	Azoarcus sp. BH72	4607778
YP_934581.1	CDS	azo3078	NC_008702.1	3387664	3388353	R	Putative transcriptional regulator, deoR-family; DeoR family transcriptional regulator	complement(3387664..3388353)	Azoarcus sp. BH72	4607779
YP_934582.1	CDS	azo3079	NC_008702.1	3388508	3388876	D	Conserved hypothetical protein. Homology to stm0409 of S. typhimurium of 46% (tremble:Q7CR38). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. no signal peptide. no TMHs.; hypothetical protein	3388508..3388876	Azoarcus sp. BH72	4607780
YP_934583.1	CDS	azo3080	NC_008702.1	3389559	3389756	D	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	3389559..3389756	Azoarcus sp. BH72	4607781
YP_934584.1	CDS	azo3081	NC_008702.1	3389852	3391024	R	Entry name:- TREMBL:Q89LX4 Identities = 310/374 (82%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; Family membership; acyl-coa dehydrogenase	complement(3389852..3391024)	Azoarcus sp. BH72	4607782
YP_934585.1	CDS	oruR2	NC_008702.1	3391123	3392256	D	Putative ornithine utilization regulator,; Specificity unclear; putative ornithine utilization regulator	3391123..3392256	Azoarcus sp. BH72	4607783
YP_934586.1	CDS	azo3083	NC_008702.1	3392619	3393011	R	Conserved hypothetical membrane protein, 44% identity to TrEMBL;Q82UI6. Has PF04247;Invasion gene expression up-regulator, SirB;IPR007360;SirB up-regulates Salmonella typhimurium invasion gene transcription. It is,however, not essential for the expression of these genes. Its function is unknown. No signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3392619..3393011)	Azoarcus sp. BH72	4609459
YP_934587.1	CDS	flp	NC_008702.1	3393105	3393806	D	Putative transcriptional regulator,; Family membership; putative transcriptional regulator	3393105..3393806	Azoarcus sp. BH72	4607784
YP_934588.1	CDS	azo3085	NC_008702.1	3393825	3395108	R	Conserved hypothetical membrane protein. Homology to CV2709 of Chromobacterium violaceum of 40% (trembl|Q7NUI9). Has PF04550;Phage holin family 2:Holins are a diverse family of proteins that cause bacterial membrane lysis during late-protein synthesis. It is thought that the temporal precision of holin-mediated lysis may occur through the buildup of a holin oligomer which causes the lysis. IPR007633;Phage_holin_2. TMHMM2 reporting 12 TMH's Present. no signal peptide.; Conserved hypothetical protein; hypothetical protein	complement(3393825..3395108)	Azoarcus sp. BH72	4608814
YP_934589.1	CDS	azo3086	NC_008702.1	3395119	3395355	R	Conserved hypothetical protein. Homology to ws1191 of W. succinogenes of 36% (trembl|Q7MRM8). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3395119..3395355)	Azoarcus sp. BH72	4607785
YP_934590.1	CDS	azo3087	NC_008702.1	3395348	3395812	R	Conserved hypothetical protein. Homology to CV2710 of C.violaceum of 41% (trembl:Q7NUI8). Pfam: Hemerythrin HHE cation binding domain Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96_ALCEU is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger. No signal peptide. No TMHs.; hypothetical protein	complement(3395348..3395812)	Azoarcus sp. BH72	4607786
YP_934591.1	CDS	norC	NC_008702.1	3396033	3396458	D	Nitric-oxide reductase subunit C (EC 1.7.99.7) (Nitric oxide reductase cytochrome c subunit) (NOR small subunit).COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION).54% IPR000345; CytC_heme_BS. Pfam; PF00034; Cytochrom_C; 1. SignalP: present TMHelix:1; High confidence in function and specificity; putative nitric-oxide reductase subunit C	3396033..3396458	Azoarcus sp. BH72	4607787
YP_934592.1	CDS	norB	NC_008702.1	3396487	3397866	D	Nitric-oxide reductase subunit B (EC 1.7.99.7) (Nitric oxide reductase cytochrome b subunit). 69% similarity to the P.stutzeri NorB protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). NorB IS THE CATALYTIC SUBUNIT OF THE ENZYME COMPLEX. SHOWS PROTON PUMP ACTIVITY ACROSS THE MEMBRANE IN DENITRIFYING BACTERIAL CELLS. THE MONONITROGEN REDUCTION IS PROBABLY COUPLED TO ELECTRON TRANSPORT PHOSPHORYLATION.Belongs to the heme-copper respiratory oxidase family. Swiss Prot: Q59647. IPR000883; COX1. PF00115; COX1; 1. TMHMM:predicted transmembrane helix present. SignalP: present ccoN: cytochrome c oxidase cbb3-type; High confidence in function and specificity; putative nitric-oxide reductase subunit B	3396487..3397866	Azoarcus sp. BH72	4609396
YP_934593.1	CDS	azo3090	NC_008702.1	3397938	3398141	D	Conserved hypothetical protein. Homology to RS05091 of R.solanacearum of 76% (trembl:Q8Y1C8). No domains present. No TMHs. No signal peptide.; hypothetical protein	3397938..3398141	Azoarcus sp. BH72	4609395
YP_934594.1	CDS	trkA1	NC_008702.1	3398151	3398831	R	Potassium uptake protein. Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH.Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins. 41% NAD_BS. IPR006037; TrkAC. IPR003148; TrkA_N. Pfam:PF02080; TrkA_C; 1. PF02254; TrkA_N; 1. Pfam:KTN: NAD-binding domain.; Specificity unclear; putative potassium uptake protein	complement(3398151..3398831)	Azoarcus sp. BH72	4607788
YP_934595.1	CDS	trkH1	NC_008702.1	3398833	3400161	R	Membrane component of the potassium uptake system. 38% Cat_transpt. IPR004772; K_transptTrk. Pfam: PF02386; TrkH; 1. SignalP.present. TMHelix:9.; High confidence in function and specificity; putative potassium uptake protein, membrane component	complement(3398833..3400161)	Azoarcus sp. BH72	4609969
YP_934596.1	CDS	azo3093	NC_008702.1	3400221	3400913	R	Two component system transcriptional regulatory protein, 53% Identity to TrEMBL;Q7W532,Q8XUU6. Has SMART;SM00448,REC, cheY-homologous receiver domain;IPR001789;CheY regulates the clockwise rotation of E. coli flagellar motors. This domain contains a phosphoacceptor site that is phosphorylated by histidine kinase homologues. Has OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription] Has PF00486, Transcriptional regulatory protein, C terminal;IPR001867 Trans_reg_C; This domain is almost always found associated with the response regulator receiver domain (see INTERPRO:IPR001789). It may play a role in DNA binding; two component system transcriptional regulatory protein	complement(3400221..3400913)	Azoarcus sp. BH72	4609971
YP_934597.1	CDS	kdpD2	NC_008702.1	3400910	3402439	R	Probable sensor for high-affinity potassium transport system,; High confidence in function and specificity; sensor for high-affinity potassium transport system	complement(3400910..3402439)	Azoarcus sp. BH72	4607789
YP_934598.1	CDS	norQ	NC_008702.1	3402633	3403433	D	Nitric-oxide reductase ATP/GTP binding component,NorQ. 68% FGGY_kin. TMHMM:present SignalP: present.; High confidence in function and specificity; nitric-oxide reductase	3402633..3403433	Azoarcus sp. BH72	4609101
YP_934599.1	CDS	azo3096	NC_008702.1	3403553	3404569	D	Conserved hypothetical iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to pbprb0648 of P. profundum (tremblnew|CAG22521). Involved in a membrane generated redox signal. Pfam: 4Fe-4S binding domain no signal peptide 4 TMHs; Conserved hypothetical protein; iron-sulfur 4Fe-4S ferredoxin transmembrane protein	3403553..3404569	Azoarcus sp. BH72	4609399
YP_934600.1	CDS	norD	NC_008702.1	3404573	3406684	D	Nitric oxide reductase NorD protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). FUNCTION UNKNOWN BUT ESSENTIAL FOR THE DENITRIFICATION PROCESS. 35% similarity to B. japonicum NorD. TREMBL:Q89QB3 InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. InterPro:SM00327:von Willebrand factor type A domain SignalP:present. TMHMM: presence of TMHhelix.; High confidence in function and specificity; nitric-oxide reductase accessory cytoplasmic protein	3404573..3406684	Azoarcus sp. BH72	4607790
YP_934601.1	CDS	azo3098	NC_008702.1	3406687	3407451	D	Putative Fnr-like transcriptional activator,; Function unclear; putative Fnr-like transcriptional activator	3406687..3407451	Azoarcus sp. BH72	4609397
YP_934602.1	CDS	serA	NC_008702.1	3407478	3408710	R	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase	complement(3407478..3408710)	Azoarcus sp. BH72	4607791
YP_934603.1	CDS	rdxB	NC_008702.1	3408745	3410151	R	Putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein. Homology to rdxB of R. sphaeroides of 39% (sprot|RDXB_RHOSH). Involved in a membrane generated redox signal; required to maintain repression of photosynthesis gene expression in the presence of oxygen. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding doamin no signal peptide probable 5 TMHs; Family membership; putative iron-sulfur 4Fe-4S ferredoxin transmembrane protein	complement(3408745..3410151)	Azoarcus sp. BH72	4609865
YP_934604.1	CDS	aau3	NC_008702.1	3410296	3410757	D	AAU3 protein precursor,; High confidence in function and specificity; AAU3 protein	3410296..3410757	Azoarcus sp. BH72	4609701
YP_934605.1	CDS	azo3102	NC_008702.1	3410759	3411988	R	Conserved hypothetical membrane protein,; Conserved hypothetical protein; hypothetical protein	complement(3410759..3411988)	Azoarcus sp. BH72	4608245
YP_934606.1	CDS	nosC	NC_008702.1	3412240	3412638	D	Conserved hypothetical cytochrome c5. Homology to nosC of A. eutrophus of 62% (trembl|Q7WX89). This basic c-type monoheme cytochrome has an unusually low redox potential compared with mitochondrial cytochrome c. It is reactive with cytochrome c oxidases but not with reductases. InterPro: Cytochrome c class I (IPR003088) Pfam: Cytorchrome C. signal peptide. no TMHs; Family membership; cytochrome c5	3412240..3412638	Azoarcus sp. BH72	4607792
YP_934607.1	CDS	azo3104	NC_008702.1	3412697	3412969	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3412697..3412969)	Azoarcus sp. BH72	4609400
YP_934608.1	CDS	azo3105	NC_008702.1	3413017	3413235	R	Conserved hypothetical protein. Homology to Rgel02003456 of Rubrivivax gelatinosus of 68% (gi|47572283|ref|ZP_00242328.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	complement(3413017..3413235)	Azoarcus sp. BH72	4607793
YP_934609.1	CDS	azo3106	NC_008702.1	3413290	3413937	R	conserved hypothetical secreted protein. Homology to TdenA01000391 of Thiobacillus denitrificans of 42% (gi|52008094|ref|ZP_00335471.1|(NBCI ENTREZ)). no domians predicted. signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3413290..3413937)	Azoarcus sp. BH72	4607794
YP_934610.1	CDS	nosL	NC_008702.1	3413940	3414467	R	Putative NosL protein. Homology to nosL of S. meliloti of 38% (trembl|O07331). NosL is one of the accessory proteins of the nos (nitrous oxide reductase) gene cluster. NosL is a monomeric protein of 18,540 MW that specifically and stoichiometrically binds Cu(I). The copper ion in NosL is ligated by a Cys residue, and one Met and one His are thought to serve as the other ligands. It is possible that NosL is a copper chaperone involved in metallocenter assembly. probable signal peptide no TMHs; Family membership; putative NosL protein	complement(3413940..3414467)	Azoarcus sp. BH72	4607795
YP_934611.1	CDS	nosY	NC_008702.1	3414476	3415291	R	Membrane protein nosY precursor.INVOLVED IN COPPER PROCESSING. Part of the ABC transporter complex nosDFY involved in copper import. Probably responsible for the translocation of the substrate across the membrane. 43% Similar to the copper permease, nosY in P.stutzeri. TREMBL:Q9F0W1 InterPro:IPR001117; Cu-oxidase. SignalP: present. Number of predicted TMHs:6; High confidence in function and specificity; putative copper transport system permease	complement(3414476..3415291)	Azoarcus sp. BH72	4609403
YP_934612.1	CDS	nosF	NC_008702.1	3415299	3416243	R	Copper transport ATP-binding protein nosF.INVOLVED IN COPPER PROCESSING/TRANSPORT.Part of the ABC transporter complex nosDFY involved in copper import. 3% ABC_tran; 1. InterPro:IPR003593; AAA_ATPase. IPR003439; ABC_transporter. InterPro:PS50101:ATP/GTP-binding site motif A (P-loop). InterPro:SM00382:AAA ATPase superfamily.; High confidence in function and specificity; putative copper transport system ATP-binding protein	complement(3415299..3416243)	Azoarcus sp. BH72	4609406
YP_934613.1	CDS	nosD	NC_008702.1	3416272	3417549	R	Copper-binding periplasmic protein precursor. INVOLVED IN COPPER PROCESSING AND TRANSPORT; IN THE ASSEMBLY OF THE COPPER CHROMOPHORES OF NITROUS OXIDE REDUCTASE.Part of the ABC transporter complex nosDFY involved in copper import. Similar to the putative periplasmic-binding protein nosD precursor from: P.fluorescens (36%)TREMBL:Q9F0W3 InterPro:IPR006633; CASH. IPR007742; NosD.IPR006626; PbH1. Pfam:PF05048; NosD; 1. Signal peptide: present.; High confidence in function and specificity; putative copper transport system periplasmic-binding protein	complement(3416272..3417549)	Azoarcus sp. BH72	4609402
YP_934614.1	CDS	nosRb	NC_008702.1	3417557	3417988	R	Conserved hypothetical transcriptional activator for nitrous-oxide reductase, C-termial domain. Homology to nosr (C-terminal domain) of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebB224(KEGG)). no domains predicted. no signal peptide. probable 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3417557..3417988)	Azoarcus sp. BH72	4609401
YP_934615.1	CDS	nosRa	NC_008702.1	3418003	3420174	R	Regulatory protein nosR. Transcriptional activation of the nitrous-oxide reductase gene nosZ. Similar to SWISSPROT: sprot|NOSR_PSEST (37% Pseudomonas stutzeri (Pseudomonas perfectomarina), regulatory protein NosR). TMHMM reporting 5 transmembrane helices. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; transcriptional activator	complement(3418003..3420174)	Azoarcus sp. BH72	4609405
YP_934616.1	CDS	nosZ	NC_008702.1	3420337	3422271	R	reduces nitrous oxide to nitrogen; nitrous-oxide reductase	complement(3420337..3422271)	Azoarcus sp. BH72	4609404
YP_934617.1	CDS	azo3114	NC_008702.1	3422454	3422729	R	Hypothetical secreted protein. no homology to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	complement(3422454..3422729)	Azoarcus sp. BH72	4609407
YP_934618.1	CDS	lysC	NC_008702.1	3423208	3424434	R	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase	complement(3423208..3424434)	Azoarcus sp. BH72	4610019
YP_934619.1	CDS	azo3116	NC_008702.1	3424699	3424995	D	Conserved hypothetical protein. Homology to NMA0336 of N.meningitidis of 59% (trembl:Q9JRG4) Has PF01381 Helix-turn-helix:IPR001387:HTH_3;This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases,various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum. No signal peptide or TMH reported present.; hypothetical protein	3424699..3424995	Azoarcus sp. BH72	4609186
YP_934620.1	CDS	azo3117	NC_008702.1	3425017	3425976	R	Conserved hypothetical protein. Homology to ne1518 of N. europaea of 43% (trembl|Q82UG8). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3425017..3425976)	Azoarcus sp. BH72	4607797
YP_934621.1	CDS	azo3118	NC_008702.1	3425991	3426446	D	Lyase, putative 6-pyruvoyl tetrahydrobiopterin synthase protein InterPro: 6-pyruvoyl tetrahydropterin synthase TIGRFAM: 6PTHBS: 6-pyruvoyl tetrahydrobiopterin synthase; Specificity unclear; 6-pyruvoyl-tetrahydropterin synthase	3425991..3426446	Azoarcus sp. BH72	4607798
YP_934622.1	CDS	azo3119	NC_008702.1	3426502	3427671	R	Entry name:- TREMBL:Q8XWM4 InterPro:- IPR001522; Desaturase. IPR005804; Fa_desat. Pfam:- PF00487; FA_desaturase; 1. Identities = 244/390 (62%) Prediction: Non-secretory protein Signal peptide probability: 0.008 Number of predicted TMHs: 3; Family membership; fatty acid desaturase	complement(3426502..3427671)	Azoarcus sp. BH72	4607799
YP_934623.1	CDS	azo3120	NC_008702.1	3427710	3429119	R	Region start changed from 3429549 to 3429093 (-456 bases); mechanosensitive ion channel	complement(3427710..3429119)	Azoarcus sp. BH72	4607800
YP_934624.1	CDS	azo3121	NC_008702.1	3429122	3429700	R	Putative endonuclease,42% Identity to TrEMBL;Q8XWM2, 33% Identity to TrEMBL;Q8VMF9. Has Signal peptide. Has PLDc, Phospholipase D. Active site motifs; The PLD superfamily includes enzymes involved in signal transduction, lipid biosynthesis, endonucleases and open reading frames in pathogenic viruses and bacteria. PLD hydrolyzes the terminal phosphodiester bond of phospholipids to phosphatidic acid and a hydrophilic constituent. Phosphatidic acid is a compound that is heavily involved in signal transduction. The common features of the family members are that they can bind to a phosphodiester moiety, and that most of these enzymes are active as bi-lobed monomers or dimers.; putative endonuclease	complement(3429122..3429700)	Azoarcus sp. BH72	4607801
YP_934625.1	CDS	azo3122	NC_008702.1	3429690	3430982	R	SUN protein; Specificity unclear; hypothetical protein	complement(3429690..3430982)	Azoarcus sp. BH72	4607802
YP_934626.1	CDS	azo3123	NC_008702.1	3430991	3432181	R	Conserved hypothetical secreted protein. Homology to ebA651 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA651(KEGG)). InterproterPro (IPR000694): Proline-rich region. SignalP reporting signal peptide. no TMHs; hypothetical protein	complement(3430991..3432181)	Azoarcus sp. BH72	4607803
YP_934627.1	CDS	purN	NC_008702.1	3432188	3432829	R	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase	complement(3432188..3432829)	Azoarcus sp. BH72	4607804
YP_934628.1	CDS	azo3125	NC_008702.1	3432869	3433585	R	Conserved hypothetical secreted protein. Homology to orf58 of Pseudomonas sp. of 42% (trembl|Q937A2(SRS)). No domains predicted. Signal P predicts signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3432869..3433585)	Azoarcus sp. BH72	4607805
YP_934629.1	CDS	mutL	NC_008702.1	3433752	3435617	D	DNA mismatch repair protein mutL. This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). InterPro: DNA mismatch repair proteins mutL/hexB/PMS1 mutl: DNA mismatch repair protein MutL; High confidence in function and specificity; DNA mismatch repair protein	3433752..3435617	Azoarcus sp. BH72	4607806
YP_934630.1	CDS	azo3127	NC_008702.1	3435648	3436235	R	Hypothetical secreted protein no homology of the entire protein to a protein of similar lengt in the data bank no domains predicted signal peptide no TMHs; hypothetical protein	complement(3435648..3436235)	Azoarcus sp. BH72	4609296
YP_934631.1	CDS	nikR	NC_008702.1	3436442	3436924	D	Inhibits transcription at high concentrations of nickel; nickel responsive regulator	3436442..3436924	Azoarcus sp. BH72	4607807
YP_934632.1	CDS	azo3129	NC_008702.1	3437106	3437372	D	Conserved hypothetical protein. Homology to orfJ of E. coli of 33% (trembl|O70046). no domains predicted .no signal peptide. no TMHs.; hypothetical protein	3437106..3437372	Azoarcus sp. BH72	4609379
YP_934633.1	CDS	dnaL	NC_008702.1	3437383	3438279	R	catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase	complement(3437383..3438279)	Azoarcus sp. BH72	4607808
YP_934634.1	CDS	miaA	NC_008702.1	3438489	3439451	D	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase	3438489..3439451	Azoarcus sp. BH72	4608637
YP_934635.1	CDS	azo3132	NC_008702.1	3439484	3440029	D	Hypothetical protein, 56% identity(71% similarity) with TrEMBL;Q6LK82 Has PF07209, Protein of unknown function (DUF1415);IPR009858; This family consists of several hypothetical bacterial proteins of around 180 residues in length. The function of this family is unknown. Signal peptide or TMH not present. EIIA-man: PTS system fructose subfamily; hypothetical protein	3439484..3440029	Azoarcus sp. BH72	4609223
YP_934636.1	CDS	azo3133	NC_008702.1	3440085	3440531	R	Hypothetical protein predicted by Glimmer/Critica. no homology of the protein to a protein of similar size. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3440085..3440531)	Azoarcus sp. BH72	4607809
YP_934637.1	CDS	azo3134	NC_008702.1	3440553	3443636	R	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q9HW27 (38% identity); SWISSPROT:Q57124 (33% identity). InterPro (IPR001036): Acriflavin resistance protein. Pfam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TMHMM predicting 12 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	complement(3440553..3443636)	Azoarcus sp. BH72	4607810
YP_934638.1	CDS	azo3135	NC_008702.1	3443646	3444743	R	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family, TREMBL:Q7W437 (52% identity); TREMBL:Q8EFT5 (32% identity). InterPro (IPR006143): Secretion protein HlyD. Pfam (PF00529): HlyD family secretion protein. TMHMM reporting one transmembrane helix. TC (8.A.1): The Membrane Fusion Protein (MFP) Family.; Family membership; membrane fusion protein	complement(3443646..3444743)	Azoarcus sp. BH72	4607811
YP_934639.1	CDS	purM	NC_008702.1	3444879	3445937	R	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase	complement(3444879..3445937)	Azoarcus sp. BH72	4607812
YP_934640.1	CDS	azo3137	NC_008702.1	3446157	3447275	D	Conserved hypothetical membrane protein. This is a family of hypothetical proteins. A number of the sequence records state they are transmembrane proteins or putative permeases.It is not clear what source suggested that these proteins might be permeases and this information should be treated with caution. TREMBL:Q82Y01: 39% identity; 58% similarity. TREMBL:Q8XW51: 37% identity; 53% similarity. InterPro:IPR002549 Pfam: PF01594:Protein of unknown function DUF70 Signal P predicted signal peptide and TMHMM predicted transmembrane helices; Conserved hypothetical protein; hypothetical protein	3446157..3447275	Azoarcus sp. BH72	4609663
YP_934641.1	CDS	azo3138	NC_008702.1	3447272	3447961	D	Region start changed from 3447165 to 3447246 (-81 bases); DnaA regulatory inactivator Hda	3447272..3447961	Azoarcus sp. BH72	4607813
YP_934642.1	CDS	azo3139	NC_008702.1	3447999	3448661	D	Haloacid dehalogenase-like hydrolase family is structurally different from the alpha/beta hydrolase family (abhydrolase). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. Similar to trembl|Q82XZ3 (63%) and to pir|B83604 (47%). Pfam (PF00702): haloacid dehalogenase-like hydrolase; Family membership; haloacid dehalogenase-like hydrolase family protein	3447999..3448661	Azoarcus sp. BH72	4607814
YP_934643.1	CDS	pcnB	NC_008702.1	3448752	3450110	D	Probable Poly(A) polymerase. Homology to pcnB of E. coli of 41% (sprot|PCNB_ECOLI) POLYMERASE THAT CREATES THE 3POLY(A) TAIL FOUND IN SOME MRNAS. SEEMS TO BE INVOLVED IN PLASMID COPY NUMBER CONTROL. Pfam: Poly A polymerase family no signal peptide no TMHs; Family membership; poly(A) polymerase	3448752..3450110	Azoarcus sp. BH72	4607815
YP_934644.1	CDS	folK	NC_008702.1	3450110	3450607	D	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK). InterPro: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase Pfam:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; High confidence in function and specificity; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	3450110..3450607	Azoarcus sp. BH72	4609512
YP_934645.1	CDS	azo3142	NC_008702.1	3450614	3450997	D	Conserved hypothetical membrane protein. Homology to PA1577 of Pseudomonas aeruginosa of 69% (trembl|Q9I3E0). Has PF04342, IPR007437;Protein of unknown function, DUF486;This family contains several proteins of uncharacterised function. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	3450614..3450997	Azoarcus sp. BH72	4608822
YP_934646.1	CDS	azo3143	NC_008702.1	3451005	3451646	D	Deoxyguanosine kinase, probable (2.7.1.113) InterPro: Thymidylate kinase DTMP_kinase: thymidylate kinase; Family membership; putative deoxyguanosine kinase	3451005..3451646	Azoarcus sp. BH72	4607816
YP_934647.1	CDS	panB	NC_008702.1	3451731	3452546	D	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase	3451731..3452546	Azoarcus sp. BH72	4607817
YP_934648.1	CDS	panC	NC_008702.1	3452563	3453390	D	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase	3452563..3453390	Azoarcus sp. BH72	4609493
YP_934649.1	CDS	azo3146	NC_008702.1	3453480	3453968	D	Region start changed from 3453406 to 3453454 (-48 bases); hypothetical protein	3453480..3453968	Azoarcus sp. BH72	4609494
YP_934650.1	CDS	pepN	NC_008702.1	3454036	3456720	R	Aminopeptidase catalyzes the removal of single amino acids from the amino terminus of small peptides and probable plays a role in their final digestion. Similar to trembl|Q8XXI8 (50%) and to sprot|AMPN_ECOLI (47%). Pfam (PF01433): Aminopeptidase N, APN (CD13); Specificity unclear; aminopeptidase N	complement(3454036..3456720)	Azoarcus sp. BH72	4607818
YP_934651.1	CDS	uspA	NC_008702.1	3456803	3457705	R	universal stress protein	complement(3456803..3457705)	Azoarcus sp. BH72	4609522
YP_934652.1	CDS	pma1	NC_008702.1	3457702	3460452	R	Probable cation-transporting ATPase (EC 3.6.3.-).Could mediate calcium influx.Integral membrane protein.Belongs to the cation transport ATPases family (P-type ATPases). Subfamily IIA. 47% similarity to the cyanobacterium Synechocystis sp. PCC 6803, pma1. protein. SWISSPROT:ATA1_SYNY3.P37367 InterPro:IPR001757; ATPase_E1-E2.IPR006068; Cation_ATPase_C.IPR004014; Cation_ATPase_N.IPR008250; E1-E2_ATPase_reg.IPR000695; H_ATPase.IPR005834; Hydrolase. Pfam:PF00689: Cation_ATPase_C;1. PF00690: Cation_ATPase_N;1. PF00122: E1-E2_ATPase;1. PF00702: Hydrolase; 1. SignalP: present. InterPro:PF00702:Haloacid dehalogenase/epoxide hydrolase family.; High confidence in function and specificity; putative cation-transporting P-type ATPase	complement(3457702..3460452)	Azoarcus sp. BH72	4610079
YP_934653.1	CDS	azo3150	NC_008702.1	3460566	3461057	R	Conserved hypothetical RDD family protein. Homology to ne0432 of N. europaea of 42% (trembl|Q82X63(SRS)). Pfam: (by Smart) RDD family This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands. signal peptide. 3 TMHs; Family membership; putative RDD family protein	complement(3460566..3461057)	Azoarcus sp. BH72	4609586
YP_934654.1	CDS	azo3151	NC_008702.1	3461066	3461431	R	Conserved hypothetical protein. Homology to ebA7126 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA7126(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(3461066..3461431)	Azoarcus sp. BH72	4607819
YP_934655.1	CDS	azo3152	NC_008702.1	3461470	3461880	R	Conserved hypothetical protein. Homology to Daro03002551 of Dechloromonas aromatica of 31% (gi|41723955|ref|ZP_00150845.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(3461470..3461880)	Azoarcus sp. BH72	4607820
YP_934656.1	CDS	azo3153	NC_008702.1	3461877	3462467	R	Probable RNA polymerase sigma factor, 62% Identity to TrEMBL;Q8XXN5, Q7P0I2. Has PF04542, Sigma-70 region 2;IPR007627, Sigma70_r2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix,interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation. Has PF04545, Sigma-70, region 4;IPR007630, Sigma70_r4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives. PF00196,Bacterial regulatory proteins, luxR family; The many bacterial transcription regulation proteins which bind DNA through a 'helix-turn-helix' motif can be classified into subfamilies on the basis of sequence similarities. One of these subfamilies which includes proteins with sizes ranging from 74 (gerE) to 901 amino acids (malT), can be further subdivided into two classes on the basis of the mechanism by which they are activated. The first is a class of regulators which belong to a two-component sensory transduction system where the protein is activated by its phosphorylation, generally on an aspartate residue,by a transmembrane kinase. The proteins that belong to this class include bvgA, comA, dctR; degU, evgA, fimZ,fixJ, gacA, glpR, narL, narP, nodW, rcsB and uhpA. The second is a class of regulators which is activated when bound to autoinducer molecules such as N-(3-oxohexanoyl)-L-homoserine lactone (OHHL. The proteins that belong to this class are carR, echR, esaR, expR, lasR, luxR, phzR, rhlR,traR and yenR. The 'helix-turn-helix' DNA-binding motif of these proteins is located in the C-terminal section of the sequence.; RNA polymerase sigma factor	complement(3461877..3462467)	Azoarcus sp. BH72	4607821
YP_934657.1	CDS	ilvI	NC_008702.1	3462564	3464276	D	Acetolactate synthase isozyme III large subunit (AHAS- III) (Acetohydroxy-acid synthase III large subunit) (ALS-III). InterPro: Acetolactate synthase large subunit biosynthetic type TIGRFAM: acolac_lg: acetolactate synthase large subunit, biosynthetic type; High confidence in function and specificity; acetolactate synthase	3462564..3464276	Azoarcus sp. BH72	4607822
YP_934658.1	CDS	ilvH	NC_008702.1	3464331	3464822	D	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit	3464331..3464822	Azoarcus sp. BH72	4609075
YP_934659.1	CDS	ilvC	NC_008702.1	3464912	3465928	D	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase	3464912..3465928	Azoarcus sp. BH72	4609074
YP_934660.1	CDS	pssA	NC_008702.1	3466062	3466856	D	This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Entry name:-SWISSPROT:PSS_HELPY identity:- 34% InterPro:- IPR000462; CDP-OH_P_trans. IPR004533; PssA. Pfam:- PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.047(YES); Family membership; putative CDP-diacylglycerol--serine O-phosphatidyltransferase	3466062..3466856	Azoarcus sp. BH72	4609070
YP_934661.1	CDS	colR	NC_008702.1	3466884	3467567	D	Two-component system regulatory protein ColR,; High confidence in function and specificity; two-component system regulatory protein	3466884..3467567	Azoarcus sp. BH72	4609640
YP_934662.1	CDS	colS	NC_008702.1	3467557	3468843	D	Two-component system sensor protein ColS,; High confidence in function and specificity; two-component system sensor protein	3467557..3468843	Azoarcus sp. BH72	4608508
YP_934663.1	CDS	azo3160	NC_008702.1	3468913	3469608	D	Similar to TREMBL:P95473 (66% identity); TREMBL:Q87X18 (66% identity); TREMBL:Q87TV0 (61% identity).; hypothetical protein	3468913..3469608	Azoarcus sp. BH72	4608509
YP_934664.1	CDS	inaA	NC_008702.1	3469605	3470279	D	Conserved hypothetical InaA protein. Homology to inaA of P. putida of 39% (gnl|keqq|ppu:PP0904(KEGG)). Pfam: Lipopolysaccharide kinase (Kdo/WaaP) family. These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. enterica. No signal peptide. No TMHs; Conserved hypothetical protein; InaA protein	3469605..3470279	Azoarcus sp. BH72	4607823
YP_934665.1	CDS	leuA1	NC_008702.1	3470652	3472187	D	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase	3470652..3472187	Azoarcus sp. BH72	4609080
YP_934666.1	CDS	azo3163	NC_008702.1	3472263	3472613	R	Conserved hypothetical membrane protein. Homology to bb2106 of B. bronchispetica of 55% (trembl|Q7WKK0(SRS)). No domains predicted. signal peptide. 2 TMHs.; Conserved hypothetical protein; hypothetical protein	complement(3472263..3472613)	Azoarcus sp. BH72	4609129
YP_934667.1	CDS	wrbA2	NC_008702.1	3472610	3473209	R	Flavoprotein wrbA. TREMBL:Q8XZ48:63% identity, 73% similarity; Q7NZW0: 61%, 72% WrbA, related to and slightly larger than flavodoxin. In Escherichia coli, this protein is produced during stationary phase, binds to the trp repressor, and makes trp operon repression more efficient. WrbA does not interact with the trp operator by itself. Three copies are found in Sinorhizobium meliloti InterPro: IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam PF00258: flavodoxin Absence of signal peptide (Signal P predicted) and Transmembrane helices (TMHMM predicted). wrbA2 identical to wrbA1 and wrbA3 by 37% and 23% respectively.; High confidence in function and specificity; tryptophan repressor binding protein	complement(3472610..3473209)	Azoarcus sp. BH72	4607824
YP_934668.1	CDS	azo3165	NC_008702.1	3473290	3474516	D	Putative membrane protein(Ribonuclease BN)36% identity to TrEMBL; Q7NZV9.TrEMBL;Q8XZ47(27% identity). Has PF03631, Ribonuclease BN-like family;IPR004664,RNase_BN;This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; High confidence in function and specificity; exoribonuclease II	3473290..3474516	Azoarcus sp. BH72	4610113
YP_934669.1	CDS	azo3166	NC_008702.1	3474504	3476027	R	Hypothetical Protein,20% identity to TrEMBL;Q9HUK7. Very Bad homology with the hits in the DB over entire length of protein. No substantial good hits available. No signal peptide or TMH reported present.; hypothetical protein	complement(3474504..3476027)	Azoarcus sp. BH72	4607825
YP_934670.1	CDS	rplU	NC_008702.1	3476239	3476550	D	50S ribosomal protein L21, 83% Identity to TrEMBL;Q7WQL6,Q7W1P0, Q8XVK8. Has PF00829, Ribosomal prokaryotic L21 protein;IPR001787 Ribosomal_L21p; Ribosomes are the particles that catalyze mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites MEDLINE:11297922,MEDLINE:11290319. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits.; 50S ribosomal protein L21	3476239..3476550	Azoarcus sp. BH72	4607826
YP_934671.1	CDS	rpmA	NC_008702.1	3476566	3476841	D	involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27	3476566..3476841	Azoarcus sp. BH72	4609780
YP_934672.1	CDS	obgE	NC_008702.1	3476915	3478141	D	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE	3476915..3478141	Azoarcus sp. BH72	4609785
YP_934673.1	CDS	proB	NC_008702.1	3478164	3479279	D	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase	3478164..3479279	Azoarcus sp. BH72	4607827
YP_934674.1	CDS	azo3171	NC_008702.1	3479458	3480543	D	Conserved hypothetical protein. Homology to ne2236 of N. europaea of 58% (trembl:Q82SS1). No domains predicted. No signal peptide. No TMHs; hypothetical protein	3479458..3480543	Azoarcus sp. BH72	4609633
YP_934675.1	CDS	azo3172	NC_008702.1	3480540	3482300	D	It belongs to the ATP-dependent AMP-binding enzyme family. Entry name Q9X7Y5 Primary accession number Q9X7Y5 Identities = 193/609 (31%) InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 2 Signal peptide probability: 0.006 Number of predicted TMHs: 0; Family membership; putative long chain fatty acid CoA ligase	3480540..3482300	Azoarcus sp. BH72	4607828
YP_934676.1	CDS	galE1	NC_008702.1	3482297	3483427	D	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). PLAYS AN ESSENTIAL ROLE IN THE INCORPORATION OF GALACTOSE INTO MENINGOCOCCAL LIPOPOLYSACCHARIDE SURFACE MOLECULES WHICH ARE IMPORTANT FOR PATHOGENESIS. hemL: glutamate-1-semialdehyde-21-amin; High confidence in function and specificity; UDP-glucose 4-epimerase	3482297..3483427	Azoarcus sp. BH72	4607829
YP_934677.1	CDS	azo3174	NC_008702.1	3483441	3484316	R	InterPro (IPR000051): SAM (and some other nucleotide) binding motif. InterPro (IPR001601): Generic methyltransferase. Pfam (PF01209): ubiE/COQ5 methyltransferase family.; Function unclear; putative methyltransferase	complement(3483441..3484316)	Azoarcus sp. BH72	4608855
YP_934678.1	CDS	azo3175	NC_008702.1	3484397	3485239	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal Peptide present. No TMH present.; hypothetical protein	complement(3484397..3485239)	Azoarcus sp. BH72	4607830
YP_934679.1	CDS	azo3176	NC_008702.1	3485581	3486774	D	Region start changed from 3485680 to 3485581 (99 bases); ABC transporter permease	3485581..3486774	Azoarcus sp. BH72	4607831
YP_934680.1	CDS	lolE3	NC_008702.1	3486774	3487988	D	part of a lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope); Specificity unclear; ABC transporter permease	3486774..3487988	Azoarcus sp. BH72	4607832
YP_934681.1	CDS	azo3178	NC_008702.1	3488167	3488946	D	Similar to TREMBL:Q82SR1 (47% identity).; hypothetical protein	3488167..3488946	Azoarcus sp. BH72	4609172
YP_934682.1	CDS	prpE	NC_008702.1	3489012	3490904	R	catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase	complement(3489012..3490904)	Azoarcus sp. BH72	4607833
YP_934683.1	CDS	azo3180	NC_008702.1	3491000	3492196	R	Putative response regulator protein,; Family membership; putative response regulator protein	complement(3491000..3492196)	Azoarcus sp. BH72	4609636
YP_934684.1	CDS	azo3181	NC_008702.1	3492225	3493199	R	Region start changed from 3493365 to 3493173 (-192 bases); dehydrogenase	complement(3492225..3493199)	Azoarcus sp. BH72	4607834
YP_934685.1	CDS	azo3182	NC_008702.1	3493390	3494259	D	Conserved hypothetical protein. Homology to Daro03003801 of Dechloromonas aromatica of 44% (gi|41722610|ref|ZP_00149605.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	3493390..3494259	Azoarcus sp. BH72	4607835
YP_934686.1	CDS	lemA2	NC_008702.1	3494332	3494907	D	Putative cytoplasmic membrane protein, lemA, 41% identity(63% similarity) to TrEMBL;Q9FA50.TrEMBL;Q7CNK7(37% identity). Has PF04011,LemA family;IPR007156;The members of this family are related to the LemA protein P71452. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.; Conserved hypothetical protein; hypothetical protein	3494332..3494907	Azoarcus sp. BH72	4607836
YP_934687.1	CDS	azo3184	NC_008702.1	3494927	3495829	D	Conserved hypothetical membrane protein. Homology to NE0281 of Nitrosomonas europaea of 34% (trembl|Q82XI9(SRS)). No domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	3494927..3495829	Azoarcus sp. BH72	4609126
YP_934688.1	CDS	abcZ	NC_008702.1	3495834	3497804	R	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter.; Family membership; ABC transporter ATP-binding protein	complement(3495834..3497804)	Azoarcus sp. BH72	4607837
YP_934689.1	CDS	azo3186	NC_008702.1	3497849	3499915	D	Probable site-specific recombinase.; Function unclear; ORF7; hypothetical protein	3497849..3499915	Azoarcus sp. BH72	4608246
YP_934690.1	CDS	azo3187	NC_008702.1	3500067	3500861	R	Conserved hypothetical serine protease. Homology to mucD of N. europaea of 50% (trembl|Q82XA8). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serin protease family (S1) (IPR001314). Pfam: Trypsin. signal peptide. no TMHs; Family membership; putative serine protease	complement(3500067..3500861)	Azoarcus sp. BH72	4609984
YP_934691.1	CDS	azo3188	NC_008702.1	3500858	3501787	R	Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) (Slt70). Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity). InterPro: SLT domain; Family membership; soluble lytic murein transglycosylase	complement(3500858..3501787)	Azoarcus sp. BH72	4607839
YP_934692.1	CDS	azo3189	NC_008702.1	3501801	3503081	R	CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear; NDPsugar dehydrogenase	complement(3501801..3503081)	Azoarcus sp. BH72	4607840
YP_934693.1	CDS	azo3190	NC_008702.1	3503118	3505919	R	In part; Function unclear; hypothetical protein	complement(3503118..3505919)	Azoarcus sp. BH72	4607841
YP_934694.1	CDS	atoC	NC_008702.1	3505919	3507280	R	Probable acetoacetate metabolism regulatory protein,; Specificity unclear; acetoacetate metabolism regulatory protein	complement(3505919..3507280)	Azoarcus sp. BH72	4607842
YP_934695.1	CDS	azo3192	NC_008702.1	3507270	3509348	R	Putative two component sensor histidine kinase,; Family membership; putative two component sensor histidine kinase	complement(3507270..3509348)	Azoarcus sp. BH72	4608365
YP_934696.1	CDS	azo3193	NC_008702.1	3509439	3510821	R	Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership; glycosyltransferase	complement(3509439..3510821)	Azoarcus sp. BH72	4607843
YP_934697.1	CDS	azo3194	NC_008702.1	3511072	3511518	D	hypothetical protein	3511072..3511518	Azoarcus sp. BH72	4607844
YP_934698.1	CDS	azo3195	NC_008702.1	3517200	3518531	R	Hypothetical protein. No known Domains/Features/Signal Peptide or TMH present. Weak Homology with hits in the database.; hypothetical protein	complement(3517200..3518531)	Azoarcus sp. BH72	4608232
YP_934699.1	CDS	thyA	NC_008702.1	3518714	3519508	D	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase	3518714..3519508	Azoarcus sp. BH72	4607846
YP_934700.1	CDS	folA	NC_008702.1	3519505	3519999	D	Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrofolate reductase; High confidence in function and specificity; FolA protein	3519505..3519999	Azoarcus sp. BH72	4609946
YP_934701.1	CDS	adiA	NC_008702.1	3520046	3522289	R	Putative orn/arg/lys decarboxylase. Homology to adiA of E. coli of 37% (sprot|ADIA_ECOLI). This family is composed of ornithine decarboxylases (ODC), arginine decarboxylases (ADC) and lysine decarboxylases (LDC), and belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase domain superfamily (fold I). These enzymes catalyse the decarboxylation of ornithine,arginine, or lysine, respectively using PLP as a co-factor. Pfam: Orn/Lys/Arg decarboxylase no signal peptide no TMHs; Specificity unclear; putative Orn/Arg/Lys decarboxylase	complement(3520046..3522289)	Azoarcus sp. BH72	4608817
YP_934702.1	CDS	dcd	NC_008702.1	3522456	3523022	R	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase	complement(3522456..3523022)	Azoarcus sp. BH72	4608281
YP_934703.1	CDS	azo3201	NC_008702.1	3523125	3524216	R	Mrp protein homolog InterPro: Domain of unknown function DUF59 desulf_FeS4: desulfoferrodoxin FeS4 iron; Function unclear; putative iron sulfur binding protein	complement(3523125..3524216)	Azoarcus sp. BH72	4608589
YP_934704.1	CDS	azo3202	NC_008702.1	3524441	3525022	D	Belongs to the ompa family. InterPro: Bacterial outer membrane protein; Function unclear; lipoprotein attached to the membrane by a lipid anchor	3524441..3525022	Azoarcus sp. BH72	4607847
YP_934705.1	CDS	metG	NC_008702.1	3525107	3527278	D	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase	3525107..3527278	Azoarcus sp. BH72	4607848
YP_934706.1	CDS	sulP2	NC_008702.1	3527498	3529189	D	Sulfate permease, SulP. Permease member of the MFS superfamily, involved in the transport of sulfate. Putative sulfate transporter ychM. InterPro: IPR002645; STAS. IPR001902; Sulph_transpt. Pfam: PF01740; STAS; 1. PF00916; Sulfate_transp; 1. SignalP: present.; High confidence in function and specificity; putative sulfate transporter	3527498..3529189	Azoarcus sp. BH72	4607849
YP_934707.1	CDS	azo3205	NC_008702.1	3529182	3529478	D	Conserved hypothetical acylphosphatase. Homology to pf0283 of P. furiosus of 56% (trembl|Q8U414). Acylphosphatase specifically catalyses the hydrolysis of the carboxyl-phosphate bond of acylphosphates, its substrates including 1,3-diphosphoglycerate and carbamyl phosphate. Although its physiological role is as yet unknown it may, however, play a part in the regulation of the glycolytic pathway and pyrimidine biosynthesis. InterPro: Acylphosphatase (IPR001792). Pfam: Acylphosphatase. no signal peptide. no TMHs.; Function unclear; acylphosphatase	3529182..3529478	Azoarcus sp. BH72	4609909
YP_934708.1	CDS	azo3206	NC_008702.1	3529488	3531545	R	alkaline phosphatase superfamily protein	complement(3529488..3531545)	Azoarcus sp. BH72	4607850
YP_934709.1	CDS	azo3207	NC_008702.1	3531569	3532429	R	Conserved hypothetical secreted protein. Homology to PA1688 of Pseudomonas aeruginosa of 54% (trembl|Q9X6R1(SRS)). No domains predicted. Signal p reporting signal peptide present. NO TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3531569..3532429)	Azoarcus sp. BH72	4607851
YP_934710.1	CDS	dnaE1	NC_008702.1	3532537	3536055	R	DNA polymerase III alpha subunit. DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3 TO 5 EXONUCLEASE ACTIVITY. THE ALPHA CHAIN IS THE DNA POLYMERASE (BY SIMILARITY). InterPro: DNA polymerase III alpha subunit TIGRFAM: polc: DNA polymerase III alpha subunit; High confidence in function and specificity; DNA-directed DNA polymerase	complement(3532537..3536055)	Azoarcus sp. BH72	4607852
YP_934711.1	CDS	qor	NC_008702.1	3536117	3537091	R	TREMBL:Q8XXD1: 69% identity, 76% similarity. Quinone oxidoreductase (EC 1.6.5.5) . qor, RSc2184; probable NADPH:quinone reductase, zeta-crystallin homolog oxidoreductase [EC:1.6.5.5] InterPro: Zinc-containing alcohol dehydrogenase superfamily InterPro:IPR002085; Adh_zn_family. IPR002364:QOR_zeta_crystal. Pfam:PF00107; ADH_zinc_N; 1 tdh: L-threonine 3-dehydrogenase; High confidence in function and specificity; NADPH:quinone reductase	complement(3536117..3537091)	Azoarcus sp. BH72	4608632
YP_934712.1	CDS	azo3210	NC_008702.1	3537116	3538288	R	Exported protein with C-terminal domain; Function unclear; hypothetical protein	complement(3537116..3538288)	Azoarcus sp. BH72	4609683
YP_934713.1	CDS	maeB2	NC_008702.1	3538418	3540706	R	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme	complement(3538418..3540706)	Azoarcus sp. BH72	4607853
YP_934714.1	CDS	parA3	NC_008702.1	3541054	3541833	D	Sporulation initiation inhibitor protein soj. INHIBITS THE INITIATION OF SPORULATION SPO0J ANTAGONIZES THIS INHIBITION. SOJ ULTIMATELY INHIBITS THE ACTIVATION (PHOSPHORYLATION) OF SPO0A. IT IS NOT REQUIRED FOR CHROMOSOME PARTITIONING. InterPro: ParA family ATPase; Function unclear; ParA family protein	3541054..3541833	Azoarcus sp. BH72	4609193
YP_934715.1	CDS	uvrD	NC_008702.1	3541853	3544072	R	DNA helicase II (EC 3.6.1.-). HAS BOTH ATPASE AND HELICASE ACTIVITIES. UNWINDS DNA DUPLEXES WITH 3 TO 5 POLARITY WITH RESPECT TO THE BOUND STRAND AND INITIATES UNWINDING MOST EFFECTIVELY WHEN A SINGLE-STRANDED REGION IS PRESENT. INVOLVED IN THE POSTINCISION EVENTS OF NUCLEOTIDE EXCISION REPAIR AND METHYL-DIRECTED MISMATCH REPAIR. InterPro: UvrD/REP helicase.; High confidence in function and specificity; DNA helicase II	complement(3541853..3544072)	Azoarcus sp. BH72	4609499
YP_934716.1	CDS	azo3214	NC_008702.1	3544402	3544728	D	Conserved hypothetical. Homology to Daro03003519 of Dechloromonas aromatica of 32% (gi|41722969|ref|ZP_00149935.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	3544402..3544728	Azoarcus sp. BH72	4610084
YP_934717.1	CDS	leuS	NC_008702.1	3544948	3547569	D	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase	3544948..3547569	Azoarcus sp. BH72	4607854
YP_934718.1	CDS	rlpB	NC_008702.1	3547581	3548096	D	rare lipoprotein B precursor; putative lipoprotein	3547581..3548096	Azoarcus sp. BH72	4607855
YP_934719.1	CDS	holA	NC_008702.1	3548093	3549103	D	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta	3548093..3549103	Azoarcus sp. BH72	4609730
YP_934720.1	CDS	proA	NC_008702.1	3549209	3550468	D	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase	3549209..3550468	Azoarcus sp. BH72	4609012
YP_934721.1	CDS	xerD	NC_008702.1	3550691	3551608	D	Tyrosine recombinase xerD. Site-specific tyrosine recombinase which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). InterPro: Phage integrase.; High confidence in function and specificity; integrase/recombinase	3550691..3551608	Azoarcus sp. BH72	4609632
YP_934722.1	CDS	ybaK	NC_008702.1	3551633	3552124	D	Putative DNA-dependent transcriptional regulator,YbaK.68% identity (75% similarity) to TrEMBL;Q748B9. TrEMBL; Q8FK79(29% identity to E.coli,ybaK).SwissProt;P37175 Has PF04073, YbaK / prolyl-tRNA synthetases associated domain;IPR007214; This domain of unknown function is found in numerous prokaryote organisms. The structure of YbaK shows a novel fold. This domain also occurs in a number of prolyl-tRNA synthetases (proRS) from prokaryotes. Thus, the domain is thought to be involved in oligo-nucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA. TIGR00011; YbaK_EbsC; 1; High confidence in function and specificity; putative transcriptional regulator	3551633..3552124	Azoarcus sp. BH72	4610128
YP_934723.1	CDS	hvrA2	NC_008702.1	3552261	3552620	D	Putative trans-acting regulatory protein HvrA. Homology to hvrA of R. capsulatus of 28% (sprot|HVRA_RHOCA) IT IS A DIM-LIGHT TRANS-ACTING ACTIVATOR OF PUF AND PUH EXPRESSION BUT HAS NO EFFECT ON THE EXPRESSION OF THE PUC OPERON. IT IS RESPONSIBLE FOR REGULATING LIGHT-HARVESTING-I AND REACTION CENTER STRUCTURAL GENE EXPRESSION DIFFERENTIALLY FROM THAT OF LIGHT-HARVESTING-II EXPRESSION IN RESPONSE TO ALTERATIONS IN LIGHT. PROPER LIGHT REGULATION OF LIGHT-HARVESTING AND REACTION CENTER POLYPEPTIDE SYNTHESIS IS INDEED AN IMPORTANT PHYSIOLOGICAL TRAIT THAT ENABLES CELLS TO ADAPT TO EVER-CHANGING ENVIRONMENTAL CONDITIONS OF LIGHT INTENSITY. InterPro: H-NS histone family (IPR001801) Pfam: H-NS histone family no signal peptide no TMHs; Family membership; putative trans-acting regulatory protein HvrA	3552261..3552620	Azoarcus sp. BH72	4610143
YP_934724.1	CDS	folB	NC_008702.1	3552711	3553088	R	Dihydroneopterin aldolase (DHNA). CATALYZES THE CONVERSION OF 78-DIHYDRONEOPTERIN TO 6- HYDROXYMETHYL-78-DIHYDROPTERIN. InterPro: Dihydroneopterin aldolase TIGRFAM: folB_dom: FolB domain; High confidence in function and specificity; FolB protein	complement(3552711..3553088)	Azoarcus sp. BH72	4609056
YP_934725.1	CDS	azo3223	NC_008702.1	3553201	3553797	D	Conserved hypothetical membrane protein.51% identity to TrEMBL;Q6D157. Has PF02660, Domain of unknown function DUF;IPR003811; This family consists of hypothetical transmembrane proteins none of which have any known function, the aligned region is around 200 amino acids long. TMHMM2 predicts 4 TMH's. Signal peptide present, but is overlapping with the DYF,PF02660 domain. SO is the TMH's.; Conserved hypothetical protein; hypothetical protein	3553201..3553797	Azoarcus sp. BH72	4608818
YP_934726.1	CDS	gcp	NC_008702.1	3553798	3554829	R	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease	complement(3553798..3554829)	Azoarcus sp. BH72	4607856
YP_934727.1	CDS	rpsU	NC_008702.1	3554961	3555173	D	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21	3554961..3555173	Azoarcus sp. BH72	4608867
YP_934728.1	CDS	dnaG	NC_008702.1	3555250	3557070	D	DNA primase (EC 2.7.7.-). DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis. MG010: DNA primase-related protein.; High confidence in function and specificity; DNA primase	3555250..3557070	Azoarcus sp. BH72	4609824
YP_934729.1	CDS	rpoD	NC_008702.1	3557120	3559108	D	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD	3557120..3559108	Azoarcus sp. BH72	4608633
YP_934730.1	CDS	gloA2	NC_008702.1	3559582	3559950	R	Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. Similar to trembl|Q9HY85 (74%) and to sprot|LGUL_NEIMA (70%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD002334): Glyoxalase I; High confidence in function and specificity; lactoylglutathione lyase	complement(3559582..3559950)	Azoarcus sp. BH72	4608239
YP_934731.1	CDS	azo3229	NC_008702.1	3559972	3560691	R	Probable Hydrogenase expression/formation protein hupH. SIMILARITY:Belongs to the hupH/hyaF family SPROT:P48340: 37% identity, 54% similarity InterPro: IPR002725; DUF45. Pfam: PF01863; DUF45 Nonsecretory protein (Signal P predicted) No transmembrane helices (TMHMM predicted); High confidence in function and specificity; putative hydrolase	complement(3559972..3560691)	Azoarcus sp. BH72	4608908
YP_934732.1	CDS	azo3230	NC_008702.1	3560730	3561479	R	Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear; hypothetical protein	complement(3560730..3561479)	Azoarcus sp. BH72	4607857
YP_934733.1	CDS	azo3231	NC_008702.1	3561476	3562246	R	Conserved hypothetical membrane protein. Homology to ebA4352 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA4352(KEGG)). Has PF04401, Protein of unknown function (DUF540); IPR007496 DUF540; Uncharacterised bacterial integral membrane protein,possibly involved in cysteine biosynthesis. Speculated to be involved in sulphate transport. no signal peptide. 6 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3561476..3562246)	Azoarcus sp. BH72	4607858
YP_934734.1	CDS	ffh	NC_008702.1	3562254	3563612	R	Signal recognition particle protein (Fifty-four homolog) (P48). NECESSARY FOR EFFICIENT EXPORT OF EXTRA-CYTOPLASMIC PROTEINS. BINDS TO THE SIGNAL SEQUENCE WHEN IT EMERGES FROM THE RIBOSOMES.The protein has a two domain structure: the G-domain binds GTP; the M-domain binds the RNA and also binds the signal sequence. It belongs to the GTP-binding SRP family. InterPro: Signal recognition particle protein 3a0501s01: signal recognition particl Pfam: SRP54-type protein (GTPase domain); signal peptide binding domain no TMHs and signal peptide; High confidence in function and specificity; signal recognition particle protein	complement(3562254..3563612)	Azoarcus sp. BH72	4607859
YP_934735.1	CDS	azo3233	NC_008702.1	3563665	3564489	D	Conserved hypothetical membrane protein. Homology to ne1459 of N. europaea of 49% (trembl|Q82UM4). Pfam: Cytochrome C assembly protein. no signal peptide. 8 TMHs; Conserved hypothetical protein; hypothetical protein	3563665..3564489	Azoarcus sp. BH72	4608759
YP_934736.1	CDS	pilB2	NC_008702.1	3564593	3566311	D	Pilus assembly protein PilB is a component of the pilus biogenesis apparatus,; High confidence in function and specificity; pilus biogenesis protein	3564593..3566311	Azoarcus sp. BH72	4607860
YP_934737.1	CDS	pilC	NC_008702.1	3566331	3567566	D	Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity; type 4 pilus biogenesis protein	3566331..3567566	Azoarcus sp. BH72	4609556
YP_934738.1	CDS	pilD	NC_008702.1	3567612	3568463	D	PilD is a prepilin peptidase processes the N-terminus of the prepilins. The processing is essential for the correct formation of the pseudopili of type IV bacterial protein secretion. Similar to pir|A39131 (58%). InterPro(PF01478): Prepilin cysteine protease (C20), type IV InterPro (PR00864): Prepilin cysteine protease (C20),type IV TMHMM reporting six TMH.; High confidence in function and specificity; prepilin peptidase	3567612..3568463	Azoarcus sp. BH72	4609557
YP_934739.1	CDS	azo3237	NC_008702.1	3568611	3568871	D	Conserved hypothetical protein. Homology to BB0113 of B.bronchiseptica of 56% (trembl:Q7WR44). No domas predicted. No TMHs. No signal peptide.; hypothetical protein	3568611..3568871	Azoarcus sp. BH72	4609558
YP_934740.1	CDS	azo3238	NC_008702.1	3568884	3569510	D	Conserved hypothetical membrane protein, 57% identity to TrEMBL;Q7W002. Has PF04367, Protein of unknown function (DUF502);IPR007462; Predicted to be an integral membrane protein. Signal Peptide present. 1 TMHs.; Conserved hypothetical protein; hypothetical protein	3568884..3569510	Azoarcus sp. BH72	4607861
YP_934741.1	CDS	aspS	NC_008702.1	3569566	3571365	D	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase	3569566..3571365	Azoarcus sp. BH72	4607862
YP_934742.1	CDS	azo3240	NC_008702.1	3571506	3573158	D	Putative response regulator,; Conserved hypothetical protein; response regulator	3571506..3573158	Azoarcus sp. BH72	4608362
YP_934743.1	CDS	azo3241	NC_008702.1	3573175	3573540	D	InterPro: Guanine-specific ribonuclease N1 and T1; Family membership; ribonuclease	3573175..3573540	Azoarcus sp. BH72	4607863
YP_934744.1	CDS	azo3242	NC_008702.1	3573537	3573992	D	Conserved hypothetical protein. Homology to XCC2280 of X.campestris of 33% (trembl:Q8P8G2). No domains predicted. No signal Peptide present. No TMH present.; hypothetical protein	3573537..3573992	Azoarcus sp. BH72	4607864
YP_934745.1	CDS	hsp18	NC_008702.1	3574142	3574567	D	Putative small heat shock protein. Homology to hsp18 of C. acetobutylicum of 35% (sprot|HS18_CLOAB) InterPro: Heat shock hsp20 (alpha crystallin) proteins family (IPR002068) Pfam: Hsp20/alpa cystallin family no signal peptide no TMHs; Function unclear; putative small heat shock protein	3574142..3574567	Azoarcus sp. BH72	4607865
YP_934746.1	CDS	argB	NC_008702.1	3574680	3575582	D	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase	3574680..3575582	Azoarcus sp. BH72	4609038
YP_934747.1	CDS	azo3245	NC_008702.1	3575587	3576747	D	Conserved hypothetical secreted protein. Homology to ebA4328 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA4328(KEGG)). no domains predicted. signal peptide. TMH in signal peptide; hypothetical protein	3575587..3576747	Azoarcus sp. BH72	4608332
YP_934748.1	CDS	fadD4	NC_008702.1	3576895	3578475	D	Esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active coa thioesters for subsequent degradation or incorporation into phospholipids, TREMBL:Q8UET3 (39% identity); TREMBL:Q988H2 (38% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase Pfam (PF00501): AMP-binding enzyme.; High confidence in function and specificity; long-chain-fatty-acid-CoA ligase	3576895..3578475	Azoarcus sp. BH72	4607866
YP_934749.1	CDS	asn	NC_008702.1	3578572	3580368	D	Asparagine synthase catalyze the conversion of aspartate to asparagine. Similar to trembl|Q82VG1 (45%) and to trembl|Q7USD1 (27%). Pfam (PF00733): Asparagine synthase; Family membership; asparagine synthase	3578572..3580368	Azoarcus sp. BH72	4608725
YP_934750.1	CDS	lysA1	NC_008702.1	3580380	3581663	D	Diaminopimelate decarboxylase,; Specificity unclear; diaminopimelate decarboxylase	3580380..3581663	Azoarcus sp. BH72	4608358
YP_934751.1	CDS	azo3249	NC_008702.1	3581684	3582433	R	Conserved hypothetical secreted protein. Homolgy to ne2159 of N. europaea of 33% (trembl|Q82SY7). InterPro: TPR repeat (IPR001440). Pfam: TPR domain signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3581684..3582433)	Azoarcus sp. BH72	4609184
YP_934752.1	CDS	azo3250	NC_008702.1	3582430	3583287	R	Conserved hypothetical protein. Homology to ne2161 of N. europaea of 45% (trembl|Q82SY5). Interpro: Esterase/lipase/thioesterase family. no damians predicted. no signal peptide. no TMHs.; hypothetical protein	complement(3582430..3583287)	Azoarcus sp. BH72	4607867
YP_934753.1	CDS	azo3251	NC_008702.1	3583284	3584120	R	Probable Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase). TREMBL:Q82SY4:40% identity, 57% similarity. InterPro:IPR000379; Ser_estrs Pfam:UPF0007:Uncharacterized protein family UPF000 thiE: thiamine-phosphate pyrophosphorylas No transmembrane helices; Function unclear; hypothetical protein	complement(3583284..3584120)	Azoarcus sp. BH72	4607868
YP_934754.1	CDS	azo3252	NC_008702.1	3584127	3584411	R	Conserved hypothetical protein. Homology to ne2163 of N. europaea of 42% (trembl|Q82SY3). Pfam: Poshpopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. no signal peptide. no TMHS; hypothetical protein	complement(3584127..3584411)	Azoarcus sp. BH72	4607869
YP_934755.1	CDS	azo3253	NC_008702.1	3584536	3585771	D	Conserved hypothetical protein. Homology to Mmc102002678 of Magnetococcus sp. MC-1 of 44% (gi|48831833|ref|ZP_00288884.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	3584536..3585771	Azoarcus sp. BH72	4607870
YP_934756.1	CDS	azo3254	NC_008702.1	3585774	3586460	D	May be related to biosynthesos of cell surface carbohydrates / polysaccharides.; hypothetical protein	3585774..3586460	Azoarcus sp. BH72	4607871
YP_934757.1	CDS	azo3255	NC_008702.1	3586547	3588568	D	Specificity unclear; acyltransferase	3586547..3588568	Azoarcus sp. BH72	4607872
YP_934758.1	CDS	azo3256	NC_008702.1	3588679	3590055	D	Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs.; Family membership; hypothetical protein	3588679..3590055	Azoarcus sp. BH72	4607873
YP_934759.1	CDS	azo3257	NC_008702.1	3590109	3591152	D	Similar to putative exopolysaccharide polymerization protein PssK; Family membership; polysaccharide polymerase	3590109..3591152	Azoarcus sp. BH72	4607874
YP_934760.1	CDS	azo3258	NC_008702.1	3591156	3592049	D	InterPro: Glycosyl transferase family 2; Function unclear; glycosyltransferase	3591156..3592049	Azoarcus sp. BH72	4607875
YP_934761.1	CDS	azo3259	NC_008702.1	3592004	3592930	R	InterPro: Glycosyl transferase family 2; Specificity unclear; glycosyltransferase	complement(3592004..3592930)	Azoarcus sp. BH72	4607876
YP_934762.1	CDS	azo3260	NC_008702.1	3593146	3594084	D	InterPro: Glycosyl transferase family 2; Specificity unclear; glycosyltransferase	3593146..3594084	Azoarcus sp. BH72	4607877
YP_934763.1	CDS	azo3261	NC_008702.1	3594077	3595309	D	Putative glycosyl transferase ypjH (EC 2.-.-.-). TIGR00022: conserved hypothetical pro; Specificity unclear; glycosyltransferase	3594077..3595309	Azoarcus sp. BH72	4607878
YP_934764.1	CDS	azo3262	NC_008702.1	3595306	3596340	D	Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	3595306..3596340	Azoarcus sp. BH72	4607879
YP_934765.1	CDS	azo3263	NC_008702.1	3596367	3597584	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. signal peptide present.; hypothetical protein	3596367..3597584	Azoarcus sp. BH72	4607880
YP_934766.1	CDS	azo3264	NC_008702.1	3597597	3599087	R	Conserved hypothetical secreted protein. Homology RB4730 of Rhodopirellula baltica of 36% (trembl|Q7US36). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(3597597..3599087)	Azoarcus sp. BH72	4607881
YP_934767.1	CDS	azo3265	NC_008702.1	3599098	3600003	R	Similar to a gene annotaed to encode a dolichol-phosphate mannosyltransferase, a glycosyltransferase that transfers a suga directly to a lipid carrier. InterPro: Glycosyl transferase family 2; Specificity unclear; glycosyltransferase	complement(3599098..3600003)	Azoarcus sp. BH72	4607882
YP_934768.1	CDS	azo3266	NC_008702.1	3600066	3601037	R	Conserved hypothetical polysacchacride deacetylase. Homology to N. europaea of N. europaea of 54% (trembl|Q82W49(SRS)). This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan. InterPro:IPR002509; Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1. no TMHs no signal peptide; Conserved hypothetical protein; polysaccharide deacetylase	complement(3600066..3601037)	Azoarcus sp. BH72	4607883
YP_934769.1	CDS	azo3267	NC_008702.1	3601034	3602380	R	Conserved hypothetical membrane protein. Homology to RferDRAFT_3275 of Rhodoferax ferrireducens of 46%. Pfam: O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. The enzyme is coded for by the gene wzy which is part of the O-antigen gene cluster. No signal peptide. 9 TMHs.; Family membership; hypothetical protein	complement(3601034..3602380)	Azoarcus sp. BH72	4607884
YP_934770.1	CDS	azo3268	NC_008702.1	3602380	3603606	R	InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(3602380..3603606)	Azoarcus sp. BH72	4607885
YP_934771.1	CDS	algD	NC_008702.1	3603654	3604970	R	[EC:1.1.1.132] , UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).,UDP-glucose/GDP-mannose dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity; GDP-mannose 6-dehydrogenase	complement(3603654..3604970)	Azoarcus sp. BH72	4607886
YP_934772.1	CDS	azo3270	NC_008702.1	3604967	3606178	R	InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(3604967..3606178)	Azoarcus sp. BH72	4608296
YP_934773.1	CDS	asnB1	NC_008702.1	3606175	3608103	R	Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. Similar to trembl|Q7USD1 (35%) and to sprot|ASNB_BACSU (30%). Pfam (PF00310): Glutamine amidotransferase class-II Pfam (PF00733): Asparagine synthase; Specificity unclear; asparagine synthetase	complement(3606175..3608103)	Azoarcus sp. BH72	4607887
YP_934774.1	CDS	azo3272	NC_008702.1	3608105	3609364	R	InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(3608105..3609364)	Azoarcus sp. BH72	4608359
YP_934775.1	CDS	asnB2	NC_008702.1	3609333	3611267	R	Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. Similar to trembl|Q81ZU7 (64%) and to trembl|Q7USD1 (37%). Pfam (PF00310): Glutamine amidotransferase class-II Pfam (PF00733): Asparagine synthase; Specificity unclear; asparagine synthetase	complement(3609333..3611267)	Azoarcus sp. BH72	4607888
YP_934776.1	CDS	azo3274	NC_008702.1	3611287	3612462	R	InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(3611287..3612462)	Azoarcus sp. BH72	4608360
YP_934777.1	CDS	azo3275	NC_008702.1	3612459	3614009	R	Conserved hypothetical membrane protein. Homology to NE1797 of Nitrosomonas europaea of 33% (trembl|Q82TS7(SRS)). no domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3612459..3614009)	Azoarcus sp. BH72	4607889
YP_934778.1	CDS	azo3276	NC_008702.1	3614065	3615168	R	Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster.; Function unclear; hypothetical protein	complement(3614065..3615168)	Azoarcus sp. BH72	4607890
YP_934779.1	CDS	azo3277	NC_008702.1	3615137	3615997	R	62% Myb_DNA_binding.IPR002509; Polysac_deacet. Pfam:PF01522; Polysacc_deac_1; 1.; hypothetical protein	complement(3615137..3615997)	Azoarcus sp. BH72	4607891
YP_934780.1	CDS	mnaA	NC_008702.1	3615997	3617154	R	UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity; UDP-N-acetylglucosamine 2-epimerase	complement(3615997..3617154)	Azoarcus sp. BH72	4607892
YP_934781.1	CDS	gspA	NC_008702.1	3617151	3618224	R	General secretion pathway protein A. Involved in a general secretion pathway (GSP) for the export of proteins. InterPro: AAA ATPase superfamily POssibly related to the biosynthesis of cell surface polysaccharide due to the presence of the gene in a polysaccharide synthesis gene cluster.; High confidence in function and specificity; MSHA biogenesis protein MshM	complement(3617151..3618224)	Azoarcus sp. BH72	4609232
YP_934782.1	CDS	azo3280	NC_008702.1	3618237	3619733	R	hypothetical protein	complement(3618237..3619733)	Azoarcus sp. BH72	4608946
YP_934783.1	CDS	wzc2	NC_008702.1	3619774	3620715	R	Putative tyrosine-protein kinase (EC 2.7.10.1).; High confidence in function and specificity; protein-tyrosine kinase	complement(3619774..3620715)	Azoarcus sp. BH72	4607893
YP_934784.1	CDS	azo3282	NC_008702.1	3620729	3622273	R	Conserved hypothetical polysaccharide chain length determinant protein. Homology to ebA4249 of Azoarcus sp. EbN1 of 66%. No signal peptide. 3 TMHS. Pfam: Wzz = Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases such as ETK_ECOLI.; Family membership; polysaccharide chain length determinant protein	complement(3620729..3622273)	Azoarcus sp. BH72	4610119
YP_934785.1	CDS	wza	NC_008702.1	3622352	3622981	R	Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ,; Family membership; polysaccharide export protein	complement(3622352..3622981)	Azoarcus sp. BH72	4607894
YP_934786.1	CDS	azo3284	NC_008702.1	3623219	3623971	D	Conserved hypothetical protein. Homology to ne2229 of N. europaea of 38% (trembl|Q82SS7). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	3623219..3623971	Azoarcus sp. BH72	4610117
YP_934787.1	CDS	azo3285	NC_008702.1	3623979	3625292	R	Conserved hypothetical secreted protein. Homology to NE2243 of Nitrosomonas europaea of 43% (trembl|Q82SR4(SRS). No domains predicted. Signal peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(3623979..3625292)	Azoarcus sp. BH72	4607895
YP_934788.1	CDS	azo3286	NC_008702.1	3625296	3626045	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q82SR3 (67% identity); TREMBL:Q92NU9 (48% identity); SWISSPROT:Q58206 (45% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; Family membership; ABC transporter ATP-binding protein	complement(3625296..3626045)	Azoarcus sp. BH72	4607896
YP_934789.1	CDS	azo3287	NC_008702.1	3626090	3626872	D	Conserved hypothetical secreted protein. Homology to NE2245 of Nitrosomonas europaea of 51% (tremble:Q82SR2). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	3626090..3626872	Azoarcus sp. BH72	4607897
YP_934790.1	CDS	azo3288	NC_008702.1	3626917	3627633	D	Putative exonuclease of the beta-lactamase fold involved in RNA processing, N-terminal fragment.; Family membership; RNA procession exonuclease	3626917..3627633	Azoarcus sp. BH72	4607898
YP_934791.1	CDS	azo3289	NC_008702.1	3627672	3628322	D	Putative exonuclease of the beta-lactamase fold involved in RNA processing, C-terminal fragment; Family membership; RNA procession exonuclease	3627672..3628322	Azoarcus sp. BH72	4607899
YP_934792.1	CDS	azo3290	NC_008702.1	3628428	3629525	R	Major outer membrane protein P.IB precursor (Protein IB) (PIB) (Porin). Serves as a slightly cation selective porin. InterPro: General diffusion Gram-negative porins L12: ribosomal protein L7/L12; Function unclear; outer membrane porin protein	complement(3628428..3629525)	Azoarcus sp. BH72	4607900
YP_934793.1	CDS	azo3291	NC_008702.1	3629820	3630890	R	Outer membrane porin protein 32 precursor (OMP32). Forms anion selective channels. InterPro: General diffusion Gram-negative porins 2A0310: amino acid permease (yeast); Function unclear; outer membrane porin protein	complement(3629820..3630890)	Azoarcus sp. BH72	4607901
YP_934794.1	CDS	rpoH	NC_008702.1	3631171	3632025	D	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32	3631171..3632025	Azoarcus sp. BH72	4607902
YP_934795.1	CDS	senC	NC_008702.1	3632080	3632682	R	SCO2 protein homolog mitochondrial precursor. Acts as a copper chaperone transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2). InterPro: SCO1/SenC TREMBL:Q8Y2G3: 56% identity, 74% similarity InterPro:IPR003782; SCO1_SenC. Pfam: PF02630; SCO1-SenC dsbE: periplasmic protein thiol:disulf Presence of signal peptide (SignalP predicted) No TMH's present; Family membership; SCO1/SenC family protein	complement(3632080..3632682)	Azoarcus sp. BH72	4609799
YP_934796.1	CDS	coxD	NC_008702.1	3632697	3633596	R	converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase	complement(3632697..3633596)	Azoarcus sp. BH72	4609864
YP_934797.1	CDS	azo3295	NC_008702.1	3633593	3634636	R	Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086).; putative cytochrome aa3 oxidase assembly protein	complement(3633593..3634636)	Azoarcus sp. BH72	4608523
YP_934798.1	CDS	azo3296	NC_008702.1	3634633	3635286	R	Conserved hypothetical membrane protein. Homology to RS03338 of Ralstonia solanacearum of 36% (trembl|Q8Y2G6(SRS)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3634633..3635286)	Azoarcus sp. BH72	4607903
YP_934799.1	CDS	azo3297	NC_008702.1	3635261	3635983	R	Conserved hypothetical secreted protein. Homology to NE1012 of N.europaea of 31% (tremble:Q82VQ4). No domains predicted. Signal peptide present. No TMHs; Conserved hypothetical protein; hypothetical protein	complement(3635261..3635983)	Azoarcus sp. BH72	4607904
YP_934800.1	CDS	azo3298	NC_008702.1	3636032	3636226	D	Conserved hypothetical membrane protein. Homology to rs0336 of R. solanacearum of 53% (trembl|Q8Y2G8(SRS)). no domains predicted. signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	3636032..3636226	Azoarcus sp. BH72	4607905
YP_934801.1	CDS	coxC	NC_008702.1	3636240	3637091	R	Cytochrome c oxidase polypeptide III Subunits I II and III form the functional core of the enzyme complex. InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity; cytochrome-c oxidase	complement(3636240..3637091)	Azoarcus sp. BH72	4607906
YP_934802.1	CDS	azo3300	NC_008702.1	3637132	3637332	R	Conserved hypothetical membrane protein, 73% similarity to TrEMBL;Q7WE10,Putative membrane protein [BB4828] [Bordetella bronchiseptica(Alcaligenes bronchisepticus). no signal peptide. 1 TMHs; hypothetical protein	complement(3637132..3637332)	Azoarcus sp. BH72	4608522
YP_934803.1	CDS	coxG	NC_008702.1	3637322	3637897	R	involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein	complement(3637322..3637897)	Azoarcus sp. BH72	4607907
YP_934804.1	CDS	azo3302	NC_008702.1	3637894	3638010	R	Conserved hypothetical membrane protein. Homology to rsc0364 of R. solanacearum of 42% (trembl|Q8Y2H2) no domains predicted no signal peptide 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3637894..3638010)	Azoarcus sp. BH72	4608524
YP_934805.1	CDS	coxA	NC_008702.1	3638035	3639612	R	Probable cytochrome c oxidase, subunit I (EC 1.9.3.1) (Cytochrome AA3 subunit 1). Homology to coxA of B. japonicum of 55% (sprot|COX1_BRAJA(SRS)) cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. subunits 1- 3 form the functional core of the enzyme complex. co i is the catalytic subunit of the enzyme. electrons originating in cytochrome c are transferred via the copper a center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper b. Pfam: Cytochrome c and quinol oxidase polypeptide no signal peptide 12 TMHs; High confidence in function and specificity; cytochrome c oxidase subunit I	complement(3638035..3639612)	Azoarcus sp. BH72	4607908
YP_934806.1	CDS	coxB	NC_008702.1	3639657	3640799	R	Conserved hypothetical cytochrome c oxidase,subunit II. Homology to bb4831 of B. bronchiseptica of 60% (trembl|Q7WE07). SUBUNIT I AND II FORM THE FUNCTIONAL CORE OF THE ENZYME COMPLEX. ELECTRONS ORIGINATING IN CYTOCHROME C ARE TRANSFERRED VIA HEME A AND CU(A) TO THE BINUCLEAR CENTER FORMED BY HEME A3 AND CU(B). InterPro: Cytochrome c oxidase subunit II (IPR002429); cytochrome c, class IC (IPR008168); cytochrome, class I (IPR003088); Cu(A) centre of cytochrome coxidase, subunit II and nitrous oxide reductase (IPR001505) Pfam: Cytochrome c oxidase subunit II, transmembran domain; cytochrome c oxidase subunit II,periplasmic domain; cytochrome c Tirgfam: ccoP: cytochrome c oxidase cbb3-type signal peptide 2 TMHs; Conserved hypothetical protein; cytochrome c oxidase subunit II	complement(3639657..3640799)	Azoarcus sp. BH72	4608520
YP_934807.1	CDS	waaE1	NC_008702.1	3641189	3641698	R	ADP-heptose synthase (EC 2.7.-.-). cyt_tran_rel: cytidyltransferase-related; High confidence in function and specificity; ADP-heptose synthase	complement(3641189..3641698)	Azoarcus sp. BH72	4608521
YP_934808.1	CDS	azo3306	NC_008702.1	3641777	3643381	R	Conserved hypothetical Na+-dependent phosphate transporter protein. Homolg to Bacteroides thetaiotaomicron. TREMBL:Q8A4R9 InterPro:IPR003841; Na/Pi_cotranspt.IPR004633; NaPi_cotransptII. Pfam:PF02690; Na_Pi_cotrans; 1. SignalP: present TMhelix:8 present. InterPro: Na+/Pi-cotransporter NaPi_cotrn_rel: Na/Pi cotransporter II Hypothetical protein yjbB.; Specificity unclear; hypothetical protein	complement(3641777..3643381)	Azoarcus sp. BH72	4610103
YP_934809.1	CDS	cat1	NC_008702.1	3643550	3645082	R	Probable coenzyme A transferase. Homology to cat1 of C. kluyveri of 51% (sprot|CAT1_CLOKL). Pfam: Acetyl-CoA hydrolase/transferase no signal peptide no TMHs tal_mycobact: transaldolase; Family membership; coenzyme A transferase	complement(3643550..3645082)	Azoarcus sp. BH72	4607909
YP_934810.1	CDS	azo3308	NC_008702.1	3645353	3646273	R	Putative MerR-family transcriptional regulator. InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif. h_aconitase: homoaconitase; MerR family transcriptional regulator	complement(3645353..3646273)	Azoarcus sp. BH72	4608420
YP_934811.1	CDS	azo3309	NC_008702.1	3646563	3647906	D	Conserved hypothetical amine oxidoreductase. Homology to atu1977 of A. tumefaciens of 47% (trembl|Q8UDY9). Pfam: Flavine containing amine oxidoreductase no signal peptide 1 TMHs; Conserved hypothetical protein; amine oxidoreductase	3646563..3647906	Azoarcus sp. BH72	4607910
YP_934812.1	CDS	azo3310	NC_008702.1	3647986	3648756	D	Conserved hypothetical protein. Homology to CV3225 of C.violaceum of 50% (trembl:Q7NPR5). Has PF07103,Protein of unknown function (DUF1365);IPR010775 ;This family consists of several bacterial and plant proteins of around 250 residues in length. The function of this family is unknown. No signal peptide or TMH present.; hypothetical protein	3647986..3648756	Azoarcus sp. BH72	4607911
YP_934813.1	CDS	cfaA	NC_008702.1	3648753	3650036	D	Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) (Cyclopropane fatty acid synthase) (CFA synthase). InterPro: Cyclopropane-fatty-acyl-phospholipid synthase; High confidence in function and specificity; cyclopropane-fatty-acyl-phospholipid synthase	3648753..3650036	Azoarcus sp. BH72	4607912
YP_934814.1	CDS	azo3312	NC_008702.1	3650039	3650623	D	Conserved hypothetical secreted protein. Homology to PP2729 of P.putida of 36% (tremble:Q88JC0). No domains predicted. Signal peptide present. NO TMH reported present.; Conserved hypothetical protein; hypothetical protein	3650039..3650623	Azoarcus sp. BH72	4608463
YP_934815.1	CDS	azo3313	NC_008702.1	3650639	3651958	D	Integral membrane protein.Belongs to the Na/galactoside symporter family. 20% MFS.IPR001927; Na/Gal_symport. TIGRFAMs:TIGR00792; gph; 1. TMHelix:12.; Function unclear; putative symporter protein	3650639..3651958	Azoarcus sp. BH72	4607913
YP_934816.1	CDS	azo3314	NC_008702.1	3651955	3652512	D	Conserved hypothetical secreted protein. Homology to PP2730 of P.putida of 48% (tremble:Q88JB9). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	3651955..3652512	Azoarcus sp. BH72	4607914
YP_934817.1	CDS	azo3315	NC_008702.1	3652517	3653299	D	The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q92PV6 (39 % identity); TREMBL:Q88JB2 (33% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase.; Specificity unclear; short-chain dehydrogenase	3652517..3653299	Azoarcus sp. BH72	4607915
YP_934818.1	CDS	azo3316	NC_008702.1	3653304	3653753	D	Conserved hypothetical protein. Homology to CV3228 of C.violaceum of 40% (trembl:Q7NT36). No domains predicted. No Signal peptide present. No TMH reported present.; hypothetical protein	3653304..3653753	Azoarcus sp. BH72	4607916
YP_934819.1	CDS	yhdH	NC_008702.1	3653743	3654726	R	TREMBL:Q881C6:69% identity; 83% similarity. Alcohol dehydrogenase (EC: 1.1.1.1) (ADH) catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD: Ethanol + NAD = Acetaldehyde + NADH Protein yhdH. InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N; FAD binding domain InterPro: Zinc-containing alcohol dehydrogenase superfamily TIGRFAM:tdh: L-threonine 3-dehydrogenase; High confidence in function and specificity; zinc-binding alcohol dehydrogenase	complement(3653743..3654726)	Azoarcus sp. BH72	4607917
YP_934820.1	CDS	recQ	NC_008702.1	3654928	3656775	D	ATP-dependent DNA helicase recQ (EC 3.6.1.-). INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA HELICASE. recq: ATP-dependent DNA helicase RecQ.; High confidence in function and specificity; ATP-dependent DNA helicase	3654928..3656775	Azoarcus sp. BH72	4610181
YP_934821.1	CDS	fkbP	NC_008702.1	3656851	3657195	R	Peptidyl-prolyl cis-trans isomerase. Homology to fkbP of N. meningitidis of 69% (sprot|FKBP_NEIMB) PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)(IPR001179) Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase no signal peptide no TMHs; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase	complement(3656851..3657195)	Azoarcus sp. BH72	4609710
YP_934822.1	CDS	msrA	NC_008702.1	3657267	3657827	R	Putative peptide methionine sulfoxide reductase. Homology to msrA of E. coli of 37% (SWISSPROT:MSRA_ECOLI) Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). InterPro: Peptide methionine sulfoxide reductase (IPR002569) Pfam: Peptide methionine sulfoxide reductase Tigrfam: msrA: peptide methionine sulfoxide reductase no signal peptide no TMHs; Family membership; putative peptide methionine sulfoxide reductase	complement(3657267..3657827)	Azoarcus sp. BH72	4608768
YP_934823.1	CDS	azo3321	NC_008702.1	3657957	3661868	R	Conserved hypothetical membrane protein. Homology to rsc2383 of R. solanacearum of 31% (trembl|Q8XWT7(SRS)). no domains predicted .no signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3657957..3661868)	Azoarcus sp. BH72	4609280
YP_934824.1	CDS	trpC	NC_008702.1	3661872	3662666	R	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase	complement(3661872..3662666)	Azoarcus sp. BH72	4607918
YP_934825.1	CDS	trpD	NC_008702.1	3662666	3663703	R	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase	complement(3662666..3663703)	Azoarcus sp. BH72	4610031
YP_934826.1	CDS	trpG	NC_008702.1	3663719	3664306	R	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II	complement(3663719..3664306)	Azoarcus sp. BH72	4610032
YP_934827.1	CDS	trpE	NC_008702.1	3664662	3666134	R	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I	complement(3664662..3666134)	Azoarcus sp. BH72	4610035
YP_934828.1	CDS	cbbZ	NC_008702.1	3666394	3667065	R	Phosphoglycolate phosphatase 1 (EC 3.1.3.18) (PGP 1). TREMBL:Q7W391: 50% identity, 65% similarity. catalytic activity: 2-phosphoglycolate + h(2)o = glycolate + phosphate. similarity:belongs to the cbby/cbbz/gph/yieh family. InterPro: Haloacid dehalogenase/epoxide hydrolase family InterPro:IPR006402; HAD-SF-IA-v3. IPR006439; HAD_SF_A_v1. IPR005833; Hlgnase/hydrlase. Pfam PF00702; Hydrolase; 1. PRINTS PR00413; HADHALOGNASE. TIGRFAMs:TIGR01549; HAD-SF-IA-v1; 1 hstdl_phs_rel: histidinol phosphatase-r; High confidence in function and specificity; phosphoglycolate phosphatase	complement(3666394..3667065)	Azoarcus sp. BH72	4610033
YP_934829.1	CDS	rpe	NC_008702.1	3667075	3667776	R	Ribulose-phosphate 3-epimerase(also known as pentose-5-phosphate 3-epimerase, PPE or Rpe), is the enzyme that converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. 71%Ribul_P_3_epim. Pfam:PF00834; Ribul_P_3_epim; 1. TIGRFAMs:TIGR01163; rpe; 1.; High confidence in function and specificity; putative ribulose-phosphate 3-epimerase	complement(3667075..3667776)	Azoarcus sp. BH72	4608422
YP_934830.1	CDS	azo3328	NC_008702.1	3667833	3670193	R	General secretion pathway protein E,; Specificity unclear; general secretion pathway protein E	complement(3667833..3670193)	Azoarcus sp. BH72	4609758
YP_934831.1	CDS	azo3329	NC_008702.1	3670262	3670960	R	Probable 35-cyclic-nucleotide phosphodiesterase precursor (EC 3.1.4.17) (PDEase) (3:5-CNP). TREMBL:Q8ZD92:28% identity, 47% similarity InterPro; IPR001279; Blactmase-like. IPR000396; Pdiesterase2. Pfam: PF00753; Lactamase_B No transmembrane helices TIGR00010: deoxyribonuclease TatD fami; Function unclear; putative 3',5'-cyclic-nucleotide phosphodiesterase	complement(3670262..3670960)	Azoarcus sp. BH72	4607919
YP_934832.1	CDS	azo3330	NC_008702.1	3671156	3671920	R	Conserved hypothetical protein which may be involved into signal transduction processes. Important Domain: Pfam:PF00498 FHA domain. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognise phosphotyrosine with relatively high affinity. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors,RNA-binding proteins and metabolic enzymes.; FHA-domain-containing protein	complement(3671156..3671920)	Azoarcus sp. BH72	4607920
YP_934833.1	CDS	pppL	NC_008702.1	3671969	3672724	R	Putative phosphoprotein phosphatase,; Family membership; putative phosphoprotein phosphatase	complement(3671969..3672724)	Azoarcus sp. BH72	4607921
YP_934834.1	CDS	sucD	NC_008702.1	3672838	3673731	R	Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha	complement(3672838..3673731)	Azoarcus sp. BH72	4609614
YP_934835.1	CDS	sucC	NC_008702.1	3673743	3674903	R	catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta	complement(3673743..3674903)	Azoarcus sp. BH72	4609905
YP_934836.1	CDS	azo3334	NC_008702.1	3675151	3675705	R	Conserved hypothetical protein. Homology to BP2542 of B.pertussis of 50% (trembl:Q7VVU4). No domains predicted. No signal peptide. No TMHs; hypothetical protein	complement(3675151..3675705)	Azoarcus sp. BH72	4609904
YP_934837.1	CDS	fimV2	NC_008702.1	3675922	3677832	D	In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear; putative type 4 pilus biogenesis	3675922..3677832	Azoarcus sp. BH72	4607922
YP_934838.1	CDS	azo3336	NC_008702.1	3677837	3678592	R	Conserved hypothetical protein,ybgI, 48% identity(67% similarity) to SwissProt;P75743(E.coli)SP|Q8XFW7. SwissProt;Q8XVA0(58% identity)Ralstonia solanacearum. TrEMBL;Q82UH6(53% identity)Nitrosomonas europaea. Has PF01784, NIF3 (NGG1p interacting factor 3);IPR002678, DUF34; This family contains several NIF3 (NGG1p interacting factor 3) protein homologues. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.; hypothetical protein	complement(3677837..3678592)	Azoarcus sp. BH72	4608765
YP_934839.1	CDS	algW	NC_008702.1	3678696	3679862	D	Probable serine protease AlgW. Homology to algW of P. aeruginosa of 48% (trembl|Q51374). InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (Also known as DHR or GLGF) (IPR001478); HtrA/DegQ protease family (IPR001940) Pfam: PDZ domain (Also known as DHR or GLGF); Trypsin no signal peptide 1 TMH; High confidence in function and specificity; serine protease AlgW	3678696..3679862	Azoarcus sp. BH72	4607923
YP_934840.1	CDS	tatC	NC_008702.1	3679908	3680675	R	Sec-independent protein translocase tatC. Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N and C termini of TatC or cpTatC are exposed to the cytoplasmic 2a6401s02: Sec-independent periplasmic Pfam: MttB family UPF0032 propable 6 TMHs, no signal peptide; High confidence in function and specificity; Sec-independent protein translocase	complement(3679908..3680675)	Azoarcus sp. BH72	4608300
YP_934841.1	CDS	tatB	NC_008702.1	3680681	3681109	R	Sec-independent protein translocase tatB. Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. no signal peptide probable TMHs: 1 TatB is essential for the secretion of these specific proteins, and forms a scaffold upon which TatC assembles in the membrane. Deletion studies have shown that it is crucial in the forming of the TAT complex, and is therefore necessary for the correct working of the system.; High confidence in function and specificity; putative Sec-independent protein translocase	complement(3680681..3681109)	Azoarcus sp. BH72	4609920
YP_934842.1	CDS	tatA	NC_008702.1	3681177	3681410	R	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A	complement(3681177..3681410)	Azoarcus sp. BH72	4609919
YP_934843.1	CDS	azo3341	NC_008702.1	3681361	3681534	D	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	3681361..3681534	Azoarcus sp. BH72	4609918
YP_934844.1	CDS	hisE	NC_008702.1	3681597	3681920	R	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase	complement(3681597..3681920)	Azoarcus sp. BH72	4607924
YP_934845.1	CDS	hisI	NC_008702.1	3681917	3682312	R	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase	complement(3681917..3682312)	Azoarcus sp. BH72	4609004
YP_934846.1	CDS	hisF	NC_008702.1	3682309	3683067	R	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF	complement(3682309..3683067)	Azoarcus sp. BH72	4609008
YP_934847.1	CDS	hisA	NC_008702.1	3683067	3683822	R	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	complement(3683067..3683822)	Azoarcus sp. BH72	4609005
YP_934848.1	CDS	hisH	NC_008702.1	3683868	3684506	R	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH	complement(3683868..3684506)	Azoarcus sp. BH72	4608999
YP_934849.1	CDS	hisB	NC_008702.1	3684561	3685190	R	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase	complement(3684561..3685190)	Azoarcus sp. BH72	4609007
YP_934850.1	CDS	hisC2	NC_008702.1	3685259	3686347	D	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase	3685259..3686347	Azoarcus sp. BH72	4609000
YP_934851.1	CDS	azo3349	NC_008702.1	3686429	3687163	R	Similar to phage protein P7. InterPro: SLT domain; Family membership; putative transglycosylase	complement(3686429..3687163)	Azoarcus sp. BH72	4609002
YP_934852.1	CDS	ampD2	NC_008702.1	3687461	3688036	R	Putative signaling protein in beta-lactamase regulation. AMPD seems not to act as a direct sensor for beta-lactams. It hydrolyzes 16-anhydro-N-acetylmuramoyl-L-alanyl-D-3glutamyl-meso- diaminopimelic acid to the tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate (By similarity), TREMBL:Q8KRJ4 (63% identity); SWISSPROT:P82974 (60% identity). Pfam (PF01510): N-acetylmuramoyl-L-alanine amidase.; High confidence in function and specificity; N-acetyl-anhydromuranmyl-L-alanine amidase	complement(3687461..3688036)	Azoarcus sp. BH72	4607925
YP_934853.1	CDS	azo3351	NC_008702.1	3688047	3688952	R	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O59091 (37% identity); TREMBL:Q7NDM5 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity; putative ABC transporter ATP-binding protein	complement(3688047..3688952)	Azoarcus sp. BH72	4608313
YP_934854.1	CDS	azo3352	NC_008702.1	3688949	3689800	R	Similar to hypothetical protein GSU1500 of Geobacter sulfurreducens PCA (16%). TMHMM2 reporting one TMhelix. Sigcleave reporting one SignalPeptide. Coils2 reporting coiled coil region; hypothetical protein	complement(3688949..3689800)	Azoarcus sp. BH72	4607926
YP_934855.1	CDS	azo3353	NC_008702.1	3689807	3690616	R	In Myxococcus xanthus pilI are co-transcribed with pilH an ABC transporter homologue required for type IV pilus biogenesis and social gliding. pilI appear to be functionally related to pilH. Similar to membrane protein of Geobacter sulfurreducens PCA (14%) and weak; Conserved hypothetical protein; hypothetical protein	complement(3689807..3690616)	Azoarcus sp. BH72	4607927
YP_934856.1	CDS	pilB	NC_008702.1	3690780	3691208	R	PilB encodes for a 14.2 kDa polypeptide showing similarity to FimF, a component of type I fimbriae of E. coli. It may be part of the pilus assembly complex or the pilus itself. (Reference: Doerr et al., 1998 Molecular Microbiology); Specificity unclear; Type IV pilus assembly protein	complement(3690780..3691208)	Azoarcus sp. BH72	4607928
YP_934857.1	CDS	pilA	NC_008702.1	3691277	3691456	R	PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity; tfp structural protein	complement(3691277..3691456)	Azoarcus sp. BH72	4609555
YP_934858.1	CDS	pilR	NC_008702.1	3691660	3693036	R	Two component system response regulator,; High confidence in function and specificity; two component system response regulator	complement(3691660..3693036)	Azoarcus sp. BH72	4609554
YP_934859.1	CDS	pilS	NC_008702.1	3693033	3694586	R	Two component system sensor protein,; High confidence in function and specificity; two component system sensor protein	complement(3693033..3694586)	Azoarcus sp. BH72	4609571
YP_934860.1	CDS	azo3358	NC_008702.1	3694588	3694929	R	Hypothetical membrane protein. No real homology of the entire protein to the data bank. no domains predicted no signal peptide 1TMH; hypothetical protein	complement(3694588..3694929)	Azoarcus sp. BH72	4609572
YP_934861.1	CDS	ybdL	NC_008702.1	3694971	3696188	R	catalyzes the transfer of an amino moiety; putative aminotransferase	complement(3694971..3696188)	Azoarcus sp. BH72	4607929
YP_934862.1	CDS	mtnA	NC_008702.1	3696278	3697354	D	isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway; methylthioribose-1-phosphate isomerase	3696278..3697354	Azoarcus sp. BH72	4610146
YP_934863.1	CDS	fucA	NC_008702.1	3697351	3698049	D	L-fuculose phosphate aldolase(L-fuculose-1-phosphate aldolase). Involved in the fucose metabolism catalyzing the third step of the pathway, L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. 41% Aldolase_II_N.IPR004782; FucA. Pfam:PF00596; Aldolase_II; 1. TIGRFAMs:TIGR01086; fucA; 1.; High confidence in function and specificity; putative L-fuculose phosphate aldolase	3697351..3698049	Azoarcus sp. BH72	4608664
YP_934864.1	CDS	glxR1	NC_008702.1	3698348	3699238	R	Putative 2-hydroxy-3-oxopropionate reductase Homology to glxR of E. coli of 39% (SWISSPROT:GLXR_ECOLI) Activity:- (R)-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H. InterPro: 3-hydroyisobutyrate dehydrogenase (IPR002204) Pfam: Nad binding domain of 6-phosphoglucanate dehydrogenase (PF03446) Tigrfam: gnd_rel: 6-phosphoglucante no signal peptide no TMHs; Family membership; putative 2-hydroxy-3-oxopropionate reductase	complement(3698348..3699238)	Azoarcus sp. BH72	4608844
YP_934865.1	CDS	glxR2	NC_008702.1	3699235	3700116	R	Probable 2-hydroxy-3-oxopropionate reductase Homology to glxR of E. coli of 46% (SWISSPROT:GLXR_ECOLI) Activity:- (R)-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H. InterPro: 3-hydroyisobutyrate dehydrogenase (IPR002204) Pfam: Nad binding domain of 6-phosphoglucanate dehydrogenase (PF03446) Tigrfam: gnd_rel: 6-phosphoglucante no signal peptide no TMHs 0; High confidence in function and specificity; 2-hydroxy-3-oxopropionate reductase	complement(3699235..3700116)	Azoarcus sp. BH72	4608922
YP_934866.1	CDS	azo3364	NC_008702.1	3700206	3701126	D	The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership; glycosyl transferase family protein	3700206..3701126	Azoarcus sp. BH72	4608923
YP_934867.1	CDS	modD	NC_008702.1	3701590	3702435	R	Putative pyrophosphorylase modD (EC 2.4.2.-). InterPro: Quinolinate phosphoribosyl transferase; Specificity unclear; putative molybdenum transport protein	complement(3701590..3702435)	Azoarcus sp. BH72	4607930
YP_934868.1	CDS	azo3366	NC_008702.1	3702524	3702907	R	Conserved hypothetical protein. Homology to rpa3088 of R. palustris of 65% (tremblnew|CAE28529). Pfam: Dinitrogenase iron-molybdenum cofactor. no signal peptide. no TMHs.; hypothetical protein	complement(3702524..3702907)	Azoarcus sp. BH72	4609254
YP_934869.1	CDS	azo3367	NC_008702.1	3702913	3703188	R	Putative NifZ Protein homolog, shares 45% similarity to SwissProt:P46040, NifZ protein entry. Has PF04319:IPR007415:NifZ domain;This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal peptide present. No TMH Present.; High confidence in function and specificity; putative NifZ protein	complement(3702913..3703188)	Azoarcus sp. BH72	4607931
YP_934870.1	CDS	fer22	NC_008702.1	3703191	3703517	R	Probable ferredoxin 2fe-2s protein. Homology to fer2 of C. pasteruianum of 43% (sprot|FER2_CLOPA). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide no TMHs; Family membership; ferredoxin 2Fe-2S protein	complement(3703191..3703517)	Azoarcus sp. BH72	4607932
YP_934871.1	CDS	azo3369	NC_008702.1	3703673	3704557	R	Pirin-like protein. TREMBL:8Y1Z6: 68% identity, 80% similarity InterPro: DUF209 InterPro:IPR008778; Pirin_C. IPR003829; Pirin_N. Pfam :PF02678; Pirin; 1. PF05726; Pirin_C TIGR00292: thiazole biosynthesis enzyme No signal peptide (Signal P predicted). No transmembrane helices (TMHMM predicted).; Specificity unclear; hypothetical protein	complement(3703673..3704557)	Azoarcus sp. BH72	4608758
YP_934872.1	CDS	acpD	NC_008702.1	3704618	3705220	R	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP (By similarity). Entry name :- SWISSPROT:ACPD_ECOLI InterPro:-IPR003680; NADHdh_2. Pfam:- PF02525; Flavodoxin_2; 1. Identities = 97/180 (53%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; acyl carrier protein phosphodiesterase	complement(3704618..3705220)	Azoarcus sp. BH72	4607933
YP_934873.1	CDS	ltrA	NC_008702.1	3705329	3706252	D	Putative transcriptional regulator, LysR family,; High confidence in function and specificity; LysR family transcriptional regulator	3705329..3706252	Azoarcus sp. BH72	4608269
YP_934874.1	CDS	dsbB	NC_008702.1	3706379	3706879	D	Disulfide bond formation protein B. Homology to dsdB of B. cepacia of 38% (BAA11858). Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the dsbA protein (By similarity). InterPro: Disulfide bond formation protein DsbB (IPR3752). Pfam: Disulfide bond formation protein DsbB signal peptide probable 3 to 4 TMHs; Family membership; putative disulfide bond formation protein B	3706379..3706879	Azoarcus sp. BH72	4609183
YP_934875.1	CDS	azo3373	NC_008702.1	3706887	3707195	R	Conserved hypothetical protein. Homology to cv1788 of C. violaceum of 33% (trembl|Q7NX41). no domains predicted. no signal peptide. no TMHS.; hypothetical protein	complement(3706887..3707195)	Azoarcus sp. BH72	4608654
YP_934876.1	CDS	azo3374	NC_008702.1	3707307	3707525	R	Homolog to the hypothetical protein ygaP from E.coli. SWISSPROT:YGAP_ECOLI InterPro: IPR001763; Rhodanese-like. Pfam: PF00581; Rhodanese; 1. TMhelix:2 present.; Function unclear; thiosulfate sulfurtransferase	complement(3707307..3707525)	Azoarcus sp. BH72	4607934
YP_934877.1	CDS	azo3375	NC_008702.1	3707522	3710800	R	AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer, TREMBL:Q8KAV4 (43% identity); SWISSPROT:P25197 (23% identity). InterPro (IPR001036): Acriflavin resistance protein. PFam (PF00873): AcrB/AcrD/AcrF family. TIGRFAM (TIGR00914): Heavy metal efflux pump, CzcA family. TIGRFAM (TIGR00915): Hydrophobe/Amphiphile Efflux-1 (HAE1) Family protein. TMHMM predicting 11 transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family.; Specificity unclear; RND efflux transporter permease	complement(3707522..3710800)	Azoarcus sp. BH72	4607935
YP_934878.1	CDS	azo3376	NC_008702.1	3710800	3711864	R	HlyD family secretion protein. The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family. SignalP predicting signal peptide. TC (2.A.6.1): The Heavy Metal Efflux (HME) Family.; Family membership; membrane fusion protein	complement(3710800..3711864)	Azoarcus sp. BH72	4607936
YP_934879.1	CDS	azo3377	NC_008702.1	3711911	3712303	R	Conserved hypothetical protein. Homology to Bcep18194_A5800 of Burkholderia sp. 383 of 53%. Pfam: CbiX. The function of CbiX is uncertain, however it is found in cobalamin biosynthesis operons and so may have a related function. Some CbiX proteins contain a striking histidine-rich region at their C-terminus, which suggests that it might be involved in metal chelation. No signal peptide. No TMHs.; hypothetical protein	complement(3711911..3712303)	Azoarcus sp. BH72	4607937
YP_934880.1	CDS	azo3378	NC_008702.1	3712312	3713148	R	Region start changed from 3713308 to 3713122 (-186 bases); HesA/MoeB/ThiF family protein	complement(3712312..3713148)	Azoarcus sp. BH72	4607938
YP_934881.1	CDS	azo3379	NC_008702.1	3713397	3714398	R	Probable metallo betalactamase related protein with 47% identity and 65% similarity (TREMBL:Q82SI4). Pfam: Chitin synthetase, SOR/SNZ family, Thiolase N-terminal domain, phosphotyrosine interaction domain. TMHMM predicted transmembrane helix.; Function unclear; hydroxyacylglutathione hydrolase	complement(3713397..3714398)	Azoarcus sp. BH72	4607939
YP_934882.1	CDS	azo3380	NC_008702.1	3714479	3715621	D	Region start changed from 3714581 to 3714479 (102 bases); putative transaminase	3714479..3715621	Azoarcus sp. BH72	4607940
YP_934883.1	CDS	azo3381	NC_008702.1	3715626	3718484	R	Hypothetical signaling protein; signaling protein	complement(3715626..3718484)	Azoarcus sp. BH72	4607941
YP_934884.1	CDS	rcp3	NC_008702.1	3718505	3718960	R	Putative two-component system regulatory protein,weak similarity to SWISSPROT: sprot|RCP1_SYNY3 (32% Synechocystis sp., response regulator Rcp1 ) InterPro: IPR001789 Response_reg. Pfam: PF00072 response_reg. SMART: SM00448 REC. Response regulator rcp1. FORMS A TWO-COMPONENT SYSTEM WITH CPH1 IN WHICH IT ACTS AS RECEIVER SUBSTRATE.; Family membership; putative two-component system regulatory protein	complement(3718505..3718960)	Azoarcus sp. BH72	4607942
YP_934885.1	CDS	cph2	NC_008702.1	3719043	3721649	R	Putative two-component system sensor protein, weak similarity to SWISSPROT: sprot|PHY1_SYNY3 (10% Synechocystis sp., Cph1) InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR003661 His_kinA_N. IPR005467 His_kinase. IPR003660 HAMP. IPR000014 PAS_domain. IPR001610 PAC motif. Pfam: PF00672 HAMP. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS domain. PF00785 PAC motif SMART: SM00304 HAMP. SM00387 HATPase_c. SM00388 HisKA. SM00091 PAS. SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices. Phytochrome-like protein cph1 (EC 2.7.3.-) (Light-regulated histidine kinase 1) (Bacteriophytochrome cph1). REGULATORY PHOTORECEPTOR WHICH EXISTS IN TWO FORMS THAT ARE REVERSIBLY INTERCONVERTIBLE BY LIGHT: THE R FORM THAT ABSORBS MAXIMALLY IN THE RED REGION OF THE SPECTRUM AND THE FR FORM THAT ABSORBS MAXIMALLY IN THE FAR-RED REGION. HAS ALSO A SLIGHT BLUE SHIFT FOR THE FAR-RED MAXIMUM. FORMS A TWO-COMPONENT SYSTEM WITH THE RCP1 RESPONSE REGULATOR.; Conserved hypothetical protein; putative two-component system sensor protein	complement(3719043..3721649)	Azoarcus sp. BH72	4609698
YP_934886.1	CDS	azo3384	NC_008702.1	3721646	3722614	R	Putative aliphatic sulfonates binding protein precursor.PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALIPHATIC SULFONATES. PUTATIVE BINDING PROTEIN. 22% SBP_bac_3. SMART: SM00062; PBPb; 1.; Specificity unclear; putative aliphatic sulfonates binding protein	complement(3721646..3722614)	Azoarcus sp. BH72	4608527
YP_934887.1	CDS	ssb	NC_008702.1	3722791	3723273	R	Single-strand binding protein (Helix-destabilizing protein). This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair (By similarity).; High confidence in function and specificity; single-strand DNA-binding protein	complement(3722791..3723273)	Azoarcus sp. BH72	4607943
YP_934888.1	CDS	azo3386	NC_008702.1	3723325	3724530	R	Hypothetical transport protein yajR. InterPro: General substrate transporters 2_A_01_02: Multidrug resistance protein; Specificity unclear; putative transport protein	complement(3723325..3724530)	Azoarcus sp. BH72	4609892
YP_934889.1	CDS	uvrA2	NC_008702.1	3724646	3727483	D	UvrABC system protein A (UvrA protein) . The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity). InterPro: Excinuclease ABC A subunit uvra: excinuclease ABC A subunit.; High confidence in function and specificity; excinuclease ABC subunit A	3724646..3727483	Azoarcus sp. BH72	4607944
YP_934890.1	CDS	azo3388	NC_008702.1	3727563	3727862	D	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	3727563..3727862	Azoarcus sp. BH72	4610081
YP_934891.1	CDS	galE2	NC_008702.1	3727870	3728883	R	UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; UDP-glucose 4-epimerase	complement(3727870..3728883)	Azoarcus sp. BH72	4607945
YP_934892.1	CDS	rplQ	NC_008702.1	3728974	3729369	R	is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17	complement(3728974..3729369)	Azoarcus sp. BH72	4608856
YP_934893.1	CDS	rpoA	NC_008702.1	3729396	3730376	R	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha	complement(3729396..3730376)	Azoarcus sp. BH72	4609776
YP_934894.1	CDS	rpsD	NC_008702.1	3730415	3731044	R	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4	complement(3730415..3731044)	Azoarcus sp. BH72	4609794
YP_934895.1	CDS	rpsK	NC_008702.1	3731059	3731448	R	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11	complement(3731059..3731448)	Azoarcus sp. BH72	4609807
YP_934896.1	CDS	rpsM	NC_008702.1	3731461	3731823	R	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13	complement(3731461..3731823)	Azoarcus sp. BH72	4609814
YP_934897.1	CDS	rpmJ	NC_008702.1	3731877	3731990	R	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36	complement(3731877..3731990)	Azoarcus sp. BH72	4609816
YP_934898.1	CDS	infA	NC_008702.1	3732016	3732234	R	stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1	complement(3732016..3732234)	Azoarcus sp. BH72	4609793
YP_934899.1	CDS	secY	NC_008702.1	3732238	3733563	R	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY	complement(3732238..3733563)	Azoarcus sp. BH72	4609082
YP_934900.1	CDS	rplO	NC_008702.1	3733578	3734012	R	late assembly protein; 50S ribosomal protein L15	complement(3733578..3734012)	Azoarcus sp. BH72	4609863
YP_934901.1	CDS	rpmD	NC_008702.1	3734014	3734196	R	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30	complement(3734014..3734196)	Azoarcus sp. BH72	4609774
YP_934902.1	CDS	rpsE	NC_008702.1	3734200	3734724	R	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5	complement(3734200..3734724)	Azoarcus sp. BH72	4609788
YP_934903.1	CDS	rplR	NC_008702.1	3734737	3735090	R	binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18	complement(3734737..3735090)	Azoarcus sp. BH72	4609808
YP_934904.1	CDS	rplF	NC_008702.1	3735102	3735635	R	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6	complement(3735102..3735635)	Azoarcus sp. BH72	4609777
YP_934905.1	CDS	rpsH	NC_008702.1	3735645	3736040	R	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8	complement(3735645..3736040)	Azoarcus sp. BH72	4609767
YP_934906.1	CDS	rpsN	NC_008702.1	3736054	3736359	R	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14	complement(3736054..3736359)	Azoarcus sp. BH72	4609811
YP_934907.1	CDS	rplE	NC_008702.1	3736367	3736906	R	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5	complement(3736367..3736906)	Azoarcus sp. BH72	4609817
YP_934908.1	CDS	rplX	NC_008702.1	3736916	3737233	R	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24	complement(3736916..3737233)	Azoarcus sp. BH72	4609766
YP_934909.1	CDS	rplN	NC_008702.1	3737246	3737614	R	50S ribosomal protein L14.; High confidence in function and specificity; 50S ribosomal protein L14	complement(3737246..3737614)	Azoarcus sp. BH72	4609783
YP_934910.1	CDS	rpsQ	NC_008702.1	3737766	3738035	R	primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17	complement(3737766..3738035)	Azoarcus sp. BH72	4609773
YP_934911.1	CDS	rpmC	NC_008702.1	3738032	3738226	R	one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29	complement(3738032..3738226)	Azoarcus sp. BH72	4609820
YP_934912.1	CDS	rplP	NC_008702.1	3738229	3738642	R	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16	complement(3738229..3738642)	Azoarcus sp. BH72	4609787
YP_934913.1	CDS	rpsC	NC_008702.1	3738642	3739424	R	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3	complement(3738642..3739424)	Azoarcus sp. BH72	4609775
YP_934914.1	CDS	rplV	NC_008702.1	3739434	3739763	R	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22	complement(3739434..3739763)	Azoarcus sp. BH72	4609806
YP_934915.1	CDS	rpsS	NC_008702.1	3739773	3740048	R	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19	complement(3739773..3740048)	Azoarcus sp. BH72	4609781
YP_934916.1	CDS	rplB	NC_008702.1	3740059	3740886	R	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2	complement(3740059..3740886)	Azoarcus sp. BH72	4609822
YP_934917.1	CDS	rplW	NC_008702.1	3740893	3741198	R	binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23	complement(3740893..3741198)	Azoarcus sp. BH72	4609763
YP_934918.1	CDS	rplD	NC_008702.1	3741195	3741815	R	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4	complement(3741195..3741815)	Azoarcus sp. BH72	4609782
YP_934919.1	CDS	rplC	NC_008702.1	3741830	3742468	R	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3	complement(3741830..3742468)	Azoarcus sp. BH72	4609765
YP_934920.1	CDS	rpsJ	NC_008702.1	3742583	3742894	R	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10	complement(3742583..3742894)	Azoarcus sp. BH72	4609764
YP_934921.1	CDS	tufA	NC_008702.1	3742952	3744142	R	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu	complement(3742952..3744142)	Azoarcus sp. BH72	4609813
YP_934922.1	CDS	fusA2	NC_008702.1	3744170	3746266	R	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G	complement(3744170..3746266)	Azoarcus sp. BH72	4610048
YP_934923.1	CDS	rpsG	NC_008702.1	3746378	3746848	R	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7	complement(3746378..3746848)	Azoarcus sp. BH72	4608849
YP_934924.1	CDS	rpsL	NC_008702.1	3746882	3747259	R	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12	complement(3746882..3747259)	Azoarcus sp. BH72	4609810
YP_934925.1	CDS	rpoC	NC_008702.1	3747393	3751607	R	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta'	complement(3747393..3751607)	Azoarcus sp. BH72	4609815
YP_934926.1	CDS	rpoB	NC_008702.1	3751682	3755815	R	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta	complement(3751682..3755815)	Azoarcus sp. BH72	4609796
YP_934927.1	CDS	rplL	NC_008702.1	3755976	3756353	R	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12	complement(3755976..3756353)	Azoarcus sp. BH72	4609795
YP_934928.1	CDS	rplJ	NC_008702.1	3756405	3756908	R	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10	complement(3756405..3756908)	Azoarcus sp. BH72	4609771
YP_934929.1	CDS	rplA	NC_008702.1	3757142	3757837	R	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1	complement(3757142..3757837)	Azoarcus sp. BH72	4609769
YP_934930.1	CDS	rplK	NC_008702.1	3757840	3758271	R	binds directly to 23S ribosomal RNA; 50S ribosomal protein L11	complement(3757840..3758271)	Azoarcus sp. BH72	4609762
YP_934931.1	CDS	nusG	NC_008702.1	3758376	3758915	R	Modulates Rho-dependent transcription termination; transcription antitermination protein NusG	complement(3758376..3758915)	Azoarcus sp. BH72	4609770
YP_934932.1	CDS	secE	NC_008702.1	3758912	3759259	R	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE	complement(3758912..3759259)	Azoarcus sp. BH72	4609435
YP_934933.1	CDS	tufB	NC_008702.1	3759422	3760612	R	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu	complement(3759422..3760612)	Azoarcus sp. BH72	4610023
YP_934934.1	CDS	dld	NC_008702.1	3761183	3762592	D	D-lactate dehydrogenase. Homology to dld of Mus musculus of 52% (trembl|Q8CIV4) CATALYZE THE STEREOSPECIFIC OXIDATION OF D-LACTATE TO PYRUVATE. InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase, N-terminal (IPR006093) Pfam: FAD binding damian; FAD linked oxidases, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership; D-lactate dehydrogenase	3761183..3762592	Azoarcus sp. BH72	4610024
YP_934935.1	CDS	azo3433	NC_008702.1	3762769	3766365	D	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; indolepyruvate ferredoxin oxidoreductase	3762769..3766365	Azoarcus sp. BH72	4608626
YP_934936.1	CDS	azo3434	NC_008702.1	3766433	3767197	D	Conserved hypothetical membrane protein. Similar to TREMBL:Q82Y44 (38% identity); TREMBL:Q7NWG1 (37% identity). TMHMM reporting four transmembrane helices. signal peptide; Conserved hypothetical protein; hypothetical protein	3766433..3767197	Azoarcus sp. BH72	4607946
YP_934937.1	CDS	azo3435	NC_008702.1	3767294	3767998	D	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank Pfam: CobQ/CobB/MinD/ParA nucleotide binding domain no signal peptide no TMHs; hypothetical protein	3767294..3767998	Azoarcus sp. BH72	4607947
YP_934938.1	CDS	flcA	NC_008702.1	3768050	3768676	R	Probable DNA-binding response regulator, LuxR family,; Specificity unclear; LuxR family DNA-binding response regulator	complement(3768050..3768676)	Azoarcus sp. BH72	4607948
YP_934939.1	CDS	azo3437	NC_008702.1	3768936	3769865	D	Conserved hypothetical secreted protein. Homology to ebA3798 of Azoarcus sp. EbN1 of 42% (gnl|keqq|eba:ebA3798(KEGG)). Pfam: DUF534. This is a family of putative secreted proteins of unknown function. signal peptide. no TMHs.; Conserved hypothetical protein; hypothetical protein	3768936..3769865	Azoarcus sp. BH72	4608770
YP_934940.1	CDS	vsrB	NC_008702.1	3769862	3771781	D	Putative virulence regulator protein,ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR003660; HAMP. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. SM00448; REC. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Specificity unclear; putative virulence regulator protein	3769862..3771781	Azoarcus sp. BH72	4607949
YP_934941.1	CDS	azo3439	NC_008702.1	3771856	3772257	D	conserved hypothetical protein. Homology to ebB122 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebB122(KEGG)). No domains predicted. NO signal peptide present. No TMH present.; hypothetical protein	3771856..3772257	Azoarcus sp. BH72	4610097
YP_934942.1	CDS	azo3440	NC_008702.1	3772274	3773446	R	Conserved hypothetical protein. Homology to pa1188 of P. aeruginosa of 40% (trembl|Q9I4F0). InterPro: CAIB/BAIF family (IPR003673). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. TIGR00106: conserved hypothetical protein; hypothetical protein	complement(3772274..3773446)	Azoarcus sp. BH72	4607950
YP_934943.1	CDS	azo3441	NC_008702.1	3773552	3774784	R	Phenylacetate-coenzyme A ligase (Phenylacetyl-CoA ligase) (PA-CoA ligase). CATALYZES THE ACTIVATION OF PHENYLACETIC ACID TO PHENYLACETYL-COA. InterPro: AMP-dependent synthetase and ligase; Function unclear; phenylacetate--CoA ligase	complement(3773552..3774784)	Azoarcus sp. BH72	4607951
YP_934944.1	CDS	livF	NC_008702.1	3774879	3775721	R	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7WQU7 (73%) and to trembl|Q89HM3 (54%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; ABC transporter ATP-binding protein	complement(3774879..3775721)	Azoarcus sp. BH72	4607952
YP_934945.1	CDS	azo3443	NC_008702.1	3775809	3777131	R	Conserved hypothetical ABC-type branched-chain amino acid transport systems, periplasmic component. Homology to Raeut03002728 of R. eutropha of 58% (gi|45519901|ref|ZP_00171452.1|(NCBI ENTREZ)). Pfam: Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure. Signal peptide present. TMH in signal peptide.; Family membership; branched chain amino acid ABC transporter periplasmic protein	complement(3775809..3777131)	Azoarcus sp. BH72	4609148
YP_934946.1	CDS	livM4	NC_008702.1	3777218	3778285	R	Putative branched-chain amino acid transport permease. Homology to livM of E. coli of 27%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. Pfam: Branched-chain amino acid transport system no signal peptide probalbe 10 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	complement(3777218..3778285)	Azoarcus sp. BH72	4607953
YP_934947.1	CDS	azo3445	NC_008702.1	3778448	3779374	R	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q881A7 (65%) and to sprot|LIVH_ECOLI (26%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting eight Tmhelix. SignalP reporting Signal peptide.; Specificity unclear; ABC transporter permease	complement(3778448..3779374)	Azoarcus sp. BH72	4609161
YP_934948.1	CDS	azo3446	NC_008702.1	3779397	3780221	R	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q881A6 (55%), to sprot|BRAF_PSEAE (34%) and to sprot|LIVG_ECOLI (33%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; ABC transporter ATP-binding protein	complement(3779397..3780221)	Azoarcus sp. BH72	4607954
YP_934949.1	CDS	acS2	NC_008702.1	3780259	3782268	R	Function:-Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates cheY, the response regulator involved in flagellar movement and chemotaxis. Activity:- ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA Entry name SWISSPROT:ACSA_ECOLI InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 1. Identities = 114/506 (22%) Number of predicted TMHs: 0; Family membership; putative Acetyl-coenzyme A synthetase	complement(3780259..3782268)	Azoarcus sp. BH72	4607955
YP_934950.1	CDS	azo3448	NC_008702.1	3782641	3783468	D	Conserved hypothetical secreted protein. Homology to Daro03001225 of Dechloromonas aromatica of 43% (gi|46141136|ref|ZP_00153001.2|(NBCI ENTREZ)). Pfam: Protein of unknown function. signal peptide. TMH in signal peptide; hypothetical protein	3782641..3783468	Azoarcus sp. BH72	4608273
YP_934951.1	CDS	hemL	NC_008702.1	3783478	3784752	R	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase	complement(3783478..3784752)	Azoarcus sp. BH72	4607956
YP_934952.1	CDS	thiE	NC_008702.1	3784828	3785448	R	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase	complement(3784828..3785448)	Azoarcus sp. BH72	4608987
YP_934953.1	CDS	thiD2	NC_008702.1	3785441	3786283	R	Phosphomethylpyrimidine kinase (HMP-phosphate kinase) (HMP-P kinase). catalyzes the phosphorylation of hmp-p to hmp-pp (by similarity) TIGRFAM: HMP-P_kinase: phosphomethylpyrimidine kinase; Specificity unclear; phosphomethylpyrimidine kinase	complement(3785441..3786283)	Azoarcus sp. BH72	4609937
YP_934954.1	CDS	rubB	NC_008702.1	3786395	3786574	D	High confidence in function and specificity; RubB protein	3786395..3786574	Azoarcus sp. BH72	4609936
YP_934955.1	CDS	pilG	NC_008702.1	3786655	3787041	D	Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilG protein. IS INVOLVED IN PILUS BIOSYNTHESIS AND TWITCHING MOTILITY. MAY ACT AS A SINGLE-DOMAIN RESPONSE REGULATOR WHOSE FUNCTION MAY BE TO RECEIVE A CERTAIN ENVIRONMENTAL SIGNAL(S) AND THEN TRANSDUCE THAT SIGNAL TO THE PILUS ASSEMBLY MACHINERY VIA SPECIFIC PROTEIN-PROTEIN INTERACTIONS.; High confidence in function and specificity; pilus protein	3786655..3787041	Azoarcus sp. BH72	4609833
YP_934956.1	CDS	pilH	NC_008702.1	3787065	3787430	D	Pilus protein, Response_reg. Pfam: PF00072; Response_reg. SMART: SM00448; REC. PilH protein. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION).; High confidence in function and specificity; pilus protein	3787065..3787430	Azoarcus sp. BH72	4609561
YP_934957.1	CDS	pilI	NC_008702.1	3787438	3787950	D	Probable pilus biogenesis protein, CheW. Protein pilI. MAY BE A PART OF A SIGNAL-TRANSDUCTION SYSTEM THAT REGULATES TWITCHING MOTILITY BY CONTROLLING PILUS FUNCTION (EXTENSION AND RETRACTION). InterPro: CheW-like domain; High confidence in function and specificity; pilus biogenesis protein	3787438..3787950	Azoarcus sp. BH72	4609562
YP_934958.1	CDS	pilJ	NC_008702.1	3788002	3790122	D	Probable pilus biogenesis protein,; High confidence in function and specificity; pilus biogenesis protein	3788002..3790122	Azoarcus sp. BH72	4609563
YP_934959.1	CDS	pilL	NC_008702.1	3790157	3796255	D	Putative pilus biogenese protein, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. IPR001789; Response_reg. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. PF00072; Response_reg. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. SM00448; REC. HTH reporting nucleic acid binding motif; Function unclear; putative pilus biogenese protein	3790157..3796255	Azoarcus sp. BH72	4609564
YP_934960.1	CDS	phrB	NC_008702.1	3796292	3797803	R	DNA photolyase (Photoreactivating enzyme). THIS ENZYME CATALYZES THE LIGHT-DEPENDENT MONOMERIZATION (300-600 NM) OF CYCLOBUTYL PYRIMIDINE DIMERS (IN CIS-SYN CONFIGURATION) WHICH ARE FORMED BETWEEN ADJACENT BASES ON THE SAME DNA STRAND UPON EXPOSURE TO ULTRAVIOLET RADIATION. TIGRFAM: phr2: deoxyribodipyrimidine photolyase.; High confidence in function and specificity; deoxyribodipyrimidine photo-lyase	complement(3796292..3797803)	Azoarcus sp. BH72	4609565
YP_934961.1	CDS	algH	NC_008702.1	3797871	3798437	D	Transcriptional regulator,; Specificity unclear; transcriptional regulator	3797871..3798437	Azoarcus sp. BH72	4609553
YP_934962.1	CDS	yqgF	NC_008702.1	3798430	3798900	D	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein	3798430..3798900	Azoarcus sp. BH72	4608297
YP_934963.1	CDS	pyrR	NC_008702.1	3798887	3799387	D	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase	3798887..3799387	Azoarcus sp. BH72	4610196
YP_934964.1	CDS	pyrB	NC_008702.1	3799380	3800339	D	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit	3799380..3800339	Azoarcus sp. BH72	4609675
YP_934965.1	CDS	pyrX	NC_008702.1	3800410	3801693	D	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase	3800410..3801693	Azoarcus sp. BH72	4609668
YP_934966.1	CDS	yggU	NC_008702.1	3801700	3801996	R	Conserved hypothetical protein. Homology to vc0458 of V. clholerae of 48% (sprot:Y458_VIBCH). InterPro: DUF167 (IPR003748). Pfam: Uncharacterized ACR, YGGU family, COF1872. no signal peptide. no TMHs; hypothetical protein	complement(3801700..3801996)	Azoarcus sp. BH72	4609676
YP_934967.1	CDS	azo3465	NC_008702.1	3802001	3802582	R	Conserved hypothetical YGGT-family protein. Homology to ne0394 of N. europae of 37% (trembl|Q82X94). This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown. InterPro: YGGT family (IPR003425). Pfam: YGGT family. no signal peptide. 5 TMHs.; Conserved hypothetical protein; hypothetical protein	complement(3802001..3802582)	Azoarcus sp. BH72	4610178
YP_934968.1	CDS	proC	NC_008702.1	3802601	3803425	R	catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase	complement(3802601..3803425)	Azoarcus sp. BH72	4607957
YP_934969.1	CDS	azo3467	NC_008702.1	3803499	3804212	R	Concerved hypothetical protein. Homology to PA0394 of P. aeruginosa of 65% (sprot|Y394_PSEAE). InterPro: Uncharacterized pyridoxal-5-phosphate dependent enzyme family UPF0001 (IPR001608). Pfam: Uncharacterized protein family UPF0001. Tigrfam: TIGR00044: conserved hypothetical protein. no signal peptide. no TMHs; hypothetical protein	complement(3803499..3804212)	Azoarcus sp. BH72	4609634
YP_934970.1	CDS	pilT	NC_008702.1	3804339	3805379	D	Tfp retraction protein PilT, involved in the twitching motility mechanism together with PilU,; High confidence in function and specificity; twitching motility protein	3804339..3805379	Azoarcus sp. BH72	4607958
YP_934971.1	CDS	pilU2	NC_008702.1	3805466	3806599	D	Tfp retraction protein PilU is involved in the Twitching Motility mechanism,; High confidence in function and specificity; twitching motility protein	3805466..3806599	Azoarcus sp. BH72	4609573
YP_934972.1	CDS	vgrG	NC_008702.1	3806788	3809505	D	Probable vgr-related protein ,44% identity(54% similarity) to TrEMBL; Q7P238.TrEMBL;Q8XRU3(44% identity). Signal Peptide Present. Has SMART;SM00438,Repressor of transcription;IPR000967, Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C,where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis; and a yeast hypothetical protein YNL023C. Has PF04524, Protein of unknown function,DUF586; IPR006533,Rhs_Vgr;This family contains a conserved region in several bacterial proteins of unknown function.; High confidence in function and specificity; Vgr-related protein	3806788..3809505	Azoarcus sp. BH72	4609575
YP_934973.1	CDS	azo3471	NC_008702.1	3809502	3811634	D	Conserved hypothetical protein. Homology to RS02436 of R.solanacearum of 41% (trembl:Q8XUG9). No domains predicted. No signal peptide present. No TMH reported present.; hypothetical protein	3809502..3811634	Azoarcus sp. BH72	4610093
YP_934974.1	CDS	azo3472	NC_008702.1	3811703	3813064	D	Conserved hypothetical secreted protein. Homology to RS02435 of R. solanarcearum of 43% (trembl|Q8XUH0(SRS)). No domains predicted. Signal Peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	3811703..3813064	Azoarcus sp. BH72	4607959
YP_934975.1	CDS	azo3473	NC_008702.1	3813157	3814398	D	Conserved hypothetical protein. Homology to RS02435 of R. solanacearum of 47% (trembl:Q8XUH0). No domains predicted. No signal peptide. No TMHs; hypothetical protein	3813157..3814398	Azoarcus sp. BH72	4607960
YP_934976.1	CDS	azo3474	NC_008702.1	3814395	3815732	D	Conserved hypothetical secreted protein. Homology to RS02435 of R. solanarcearum of 44% (trembl|Q8XUH0(SRS)). No domains predicted. Signal Peptide present. No TMH reported present; Conserved hypothetical protein; hypothetical protein	3814395..3815732	Azoarcus sp. BH72	4607961
YP_934977.1	CDS	azo3475	NC_008702.1	3815864	3817339	R	Putative mcp-domain signal transduction protein,; Conserved hypothetical protein; MCP-domain-containing signal transduction protein	complement(3815864..3817339)	Azoarcus sp. BH72	4607962
YP_934978.1	CDS	azo3476	NC_008702.1	3817314	3817835	R	Putative signal-transduction sensor protein,; Conserved hypothetical protein; putative signal-transduction sensor protein	complement(3817314..3817835)	Azoarcus sp. BH72	4607963
YP_934979.1	CDS	azo3477	NC_008702.1	3817884	3819047	R	hypothetical protein	complement(3817884..3819047)	Azoarcus sp. BH72	4607964
YP_934980.1	CDS	azo3478	NC_008702.1	3819301	3819513	R	Conserved hypothetical secreted protein. Homology to rsc2369 of R. solanacearum of 52% (trembl|Q8XWV1). no damians predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(3819301..3819513)	Azoarcus sp. BH72	4607965
YP_934981.1	CDS	fdhC	NC_008702.1	3819510	3820550	R	Putative formate dehydrogenase gamma subunit. Homology to fdhC of W. succinogenes of 21% (TREMBL:P28180). Formate dehydrogenase is a membrane-bound complex, formed of at least three different subunits; probable heterotetramer of two FDHA, one FDHB and one FDHC. FdhC probably anchors the enzyme in the membrane and IS PROBABLY THE CYTOCHROME B556(FDO) COMPONENT. no good domains signal peptide 5 TMHs; Family membership; putative formate dehydrogenase subunit gamma	complement(3819510..3820550)	Azoarcus sp. BH72	4607966
YP_934982.1	CDS	azo3480	NC_008702.1	3820561	3820794	R	Conserved hypothetical secreted protein. Homology to rsc2371 of R. solanacearum of 36% (trembl|Q8XWU9). no doamins predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(3820561..3820794)	Azoarcus sp. BH72	4608743
YP_934983.1	CDS	fdhB	NC_008702.1	3820791	3821399	R	probable formate dehydrogenase iron-sulfur subunit. Homology to fdhB of W. succinogenes of 63% (SWISSPROT:FDHB_WOLSU) THIS CHAIN IS AN ELECTRON TRANSFER UNIT CONTAINING 18 CYSTEINE RESIDUES 16 OF WHICH OCCUR IN THREE CLUSTERS. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450); 7Fe ferredoxin (IPR000813); 3Fe-4S ferredoxin (IPR001080) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity; formate dehydrogenase iron-sulfur subunit	complement(3820791..3821399)	Azoarcus sp. BH72	4607967
YP_934984.1	CDS	fdhA2	NC_008702.1	3821419	3824322	R	Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity; formate dehydrogenase subunit alpha	complement(3821419..3824322)	Azoarcus sp. BH72	4608742
YP_934985.1	CDS	azo3483	NC_008702.1	3824336	3824572	R	Conserved hypothetical secreted protein. Homology to rsc2374 of R. solanacearum of 39% (trembl|Q8XWU6). no domains predicted. signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3824336..3824572)	Azoarcus sp. BH72	4608741
YP_934986.1	CDS	torD	NC_008702.1	3824610	3825233	R	Putative Chaperone protein TorD. Homology to torD of E. coli of 23% (sprot|TORD_ECOLI). This family consists of several bacterial TorD proteins. Many prokaryotic molybdoenzymes, for example the TMAO reductase (TorA) of Escherichia coli, require the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make it competent to receive the cofactor. Pfam: Cytoplasmic chaperon no signal peptide no TMHs; Family membership; putative chaperone protein TorD	complement(3824610..3825233)	Azoarcus sp. BH72	4607968
YP_934987.1	CDS	azo3485	NC_008702.1	3825247	3827352	R	Conserved hypothetical iron-sulfur binding protein. Homology to pb1470 of B. pertussis of 48% (trembl|Q7VY84). Transfer of electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; Family membership; iron-sulfur cluster-binding protein	complement(3825247..3827352)	Azoarcus sp. BH72	4609964
YP_934988.1	CDS	azo3486	NC_008702.1	3827941	3828564	R	Conserved hypothetical protein. Homology to RS01168 of R.solanacearum of 40% (trembl:Q8XWU3). No domains predicted. No signal peptide or TMH reported present.; hypothetical protein	complement(3827941..3828564)	Azoarcus sp. BH72	4607969
YP_934989.1	CDS	azo3487	NC_008702.1	3828561	3829046	R	Conserved hypothetical protein. Homology to BPP1929 of B.parapertussis of 34% (trembl:34%). No signal peptide or TMH reported present. No domains predicted.; hypothetical protein	complement(3828561..3829046)	Azoarcus sp. BH72	4607970
YP_934990.1	CDS	fdhD	NC_008702.1	3829147	3830031	D	Putative formate dehydrogenase accessory protein. Homology to fdhD of W. succinogenes of 20% (sprot|FDHD_WOLSU). Necessary for formate dehydrogenase activity (By similarity). InterPro: Formate dehydrogenase subunit FdhD (IPR003786). Pfam: FdhD/NarQ family no signal peptide no TMHs; Family membership; putative formate dehydrogenase accessory protein	3829147..3830031	Azoarcus sp. BH72	4607971
YP_934991.1	CDS	mobA	NC_008702.1	3830028	3830669	D	Probable molybdopterin-guanine dinucleotide biosynthesis protein A, 46% Identity to SwissProt;Q8Y0K5. TrEMBL;Q62LV3(44% Identity)Q63S71 Has PF01128,Uncharacterized protein family UPF0007;IPR001228 ISPD_synthase; The bacterial ispD protein catalyzes the third step of the deoxyxylulose-5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate.; molybdopterin-guanine dinucleotide biosynthesis protein A	3830028..3830669	Azoarcus sp. BH72	4608744
YP_934992.1	CDS	azo3490	NC_008702.1	3830659	3831579	D	Conserved hypothetical protein. Homology to ebA2947 of Azoarcus sp. EbN1 of 58% (gnl|keqq|eba:ebA2947(KEGG)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	3830659..3831579	Azoarcus sp. BH72	4609245
YP_934993.1	CDS	mobB2	NC_008702.1	3831592	3832095	R	Molybdopterin-guanine dinucleotide biosynthesis protein B. MAY BIND THE GUANINE NUCLEOTIDE REQUIRED FOR THE SYNTHESIS OF MOLYBDOPTERIN GUANINE DINUCLEOTIDE. InterPro: ATP/GTP-binding site motif A (P-loop) TIGRFAM: mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity; molybdopterin-guanine dinucleotide biosynthesis protein B	complement(3831592..3832095)	Azoarcus sp. BH72	4607972
YP_934994.1	CDS	azo3492	NC_008702.1	3832128	3834263	R	Putative sensor histidine kinase, His_kinA_N. IPR009082; His_kin_homodim. IPR003660; HAMP. IPR003594; ATPbind_ATPase. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. TMHMM reporting 2 transmembrane helices.; Specificity unclear; putative sensor histidine kinase	complement(3832128..3834263)	Azoarcus sp. BH72	4609247
YP_934995.1	CDS	sasR	NC_008702.1	3834272	3835684	R	Probable sigma-54 dependent response regulator,AAA_ATPase. IPR008931; FIS-like. IPR002197; HTH_Fis. IPR010114; NtrC. IPR001789; Response_reg. IPR008298; Res_reg_NtrC. IPR002078; Sig54_interact. Pfam: PF02954; HTH_8. PF00072; Response_reg. PF00158; Sigma54_activat. SMART: SM00382; AAA. SM00448; REC. HTH reporting reporting nucleic acid binding motif.; Family membership; sigma-54 dependent response regulator	complement(3834272..3835684)	Azoarcus sp. BH72	4607973
YP_934996.1	CDS	azo3494	NC_008702.1	3835728	3836138	R	Conserved hypothetical membrane protein. Homology to CV0155 of Chromobacterium violaceum of 69% (trembl|Q7P1Q8). Has PF03653, Uncharacterised protein family (UPF0093);IPR005265, Cons_hypoth701:It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. No signal peptide. 4 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3835728..3836138)	Azoarcus sp. BH72	4609838
YP_934997.1	CDS	azo3495	NC_008702.1	3836156	3837034	R	55%; Specificity unclear; hypothetical protein	complement(3836156..3837034)	Azoarcus sp. BH72	4607974
YP_934998.1	CDS	ascD	NC_008702.1	3837056	3838075	D	catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose; CDP-6-deoxy-delta-3,4-glucoseen reductase	3837056..3838075	Azoarcus sp. BH72	4607975
YP_934999.1	CDS	azo3497	NC_008702.1	3838095	3839231	D	conserved hypothetical regulator protein,; Conserved hypothetical protein; putative regulator protein	3838095..3839231	Azoarcus sp. BH72	4608356
YP_935000.1	CDS	azo3498	NC_008702.1	3839343	3841346	D	Putative sensor protein, no significant homology. Best Hit SWISSPROT: sprot|ZRAS_SALTY (10% Salmonella typhimurium, ZraS) InterPro: IPR003594; ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. Pfam: PF02518; HATPase_c. PF00512; HisKA. SMART: SM00387; HATPase_c. SM00388; HisKA. Signal P reporting signal peptide. Sensor protein zraS (EC 2.7.3.-). Member of the two-component regulatory system zraS/zraR. May function as a membrane-associated protein kinase that phosphorylates zraR in response to high concentrations of zinc or lead in the medium (By similarity).; putative sensor protein	3839343..3841346	Azoarcus sp. BH72	4607976
YP_935001.1	CDS	azo3499	NC_008702.1	3841404	3843584	D	Conserved hypothetical signaling protein. Homology to Daro03001340 of Dechloromonas aromatica of 45% (gi|53730727|ref|ZP_00348932.1|(NBCI ENTREZ)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. IPR001633 EAL. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM: TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain.; Conserved hypothetical protein; putative signaling protein	3841404..3843584	Azoarcus sp. BH72	4607977
YP_935002.1	CDS	cyt2	NC_008702.1	3843766	3844074	R	probable cytochrome c-552 precursor. Homology to cyt of N. europaea of 52% (AAB46987). ELECTRON DONOR FOR CYTOCHROME CD1 IN NITRITE AND NITRATE RESPIRATION. InterPro: Cytochrome c class I (IPR003088); cytochrome c,class ID (IPR002324) Pfam: cytochrome c signal peptide no TMHs; High confidence in function and specificity; cytochrome c-552	complement(3843766..3844074)	Azoarcus sp. BH72	4607978
YP_935003.1	CDS	ureG	NC_008702.1	3844213	3844836	R	Urease accessory protein ureG. Homology to ureG of K. aerognes of 71% (AAA25154). Probably facilitates nickel incorporation. Pfam: HypB/UreG nucleotide-binding domain Tigrfam: ureG: urease accessory protein UreG no signal peptide no TMHs; High confidence in function and specificity; urease accessory protein UreG	complement(3844213..3844836)	Azoarcus sp. BH72	4608568
YP_935004.1	CDS	ureF	NC_008702.1	3845086	3845790	R	Probable urease accessory protein ureF. Homology to ureF of K. aerogenes of 41% (sprot|UREF_KLEAE). UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to noncarbamylated protein InterPro: UreF (IPR002639) Pfam: ureF probable signal peptide no TMHs; High confidence in function and specificity; urease accessory protein UreF	complement(3845086..3845790)	Azoarcus sp. BH72	4610075
YP_935005.1	CDS	ureE	NC_008702.1	3845787	3846266	R	involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE	complement(3845787..3846266)	Azoarcus sp. BH72	4610074
YP_935006.1	CDS	ureC	NC_008702.1	3846323	3848029	R	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha	complement(3846323..3848029)	Azoarcus sp. BH72	4607979
YP_935007.1	CDS	azo3505	NC_008702.1	3848031	3848336	R	Region start changed from 3848352 to 3848310 (-42 bases); urease subunit beta	complement(3848031..3848336)	Azoarcus sp. BH72	4610072
YP_935008.1	CDS	azo3506	NC_008702.1	3848368	3848667	R	Conserved hypothetical protein. Homology to Daro03003730 of Dechloromonas aromatica of 40% (gi|46140350|ref|ZP_00203571.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; Family membership; hypothetical protein	complement(3848368..3848667)	Azoarcus sp. BH72	4607980
YP_935009.1	CDS	ureA	NC_008702.1	3848714	3849016	R	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma	complement(3848714..3849016)	Azoarcus sp. BH72	4607981
YP_935010.1	CDS	ureD	NC_008702.1	3849059	3849916	R	Putative urease accessory protein ureD. PROBABLY FACILITATES NICKEL INCORPORATION. SEEMS TO BE ESSENTIAL FOR UREOLYSIS. InterPro: UreD urease accessory protein Pfam: UreeD urease accessory protein no signal peptide no TMHs; High confidence in function and specificity; putative urease accessory protein UreD	complement(3849059..3849916)	Azoarcus sp. BH72	4610071
YP_935011.1	CDS	queF	NC_008702.1	3850094	3850939	R	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase	complement(3850094..3850939)	Azoarcus sp. BH72	4610073
YP_935012.1	CDS	azo3510	NC_008702.1	3850971	3853019	R	InterPro: Sulfatase Membrane protein; Specificity unclear; sulfatase family protein	complement(3850971..3853019)	Azoarcus sp. BH72	4608866
YP_935013.1	CDS	azo3511	NC_008702.1	3853231	3854097	R	Conserved hypothetical secreted protein. Homology to PA0234 of P.aeruginosa of 43% (trembl:Q9I6Q4). No domains predicted. Signal peptide present. No TMH present.; Conserved hypothetical protein; hypothetical protein	complement(3853231..3854097)	Azoarcus sp. BH72	4607982
YP_935014.1	CDS	ssuA	NC_008702.1	3854510	3855544	D	Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import.Similar to the putative periplasmic-binding protein ssuA precursor in E.coli. SSUA_BACSU:P40400. InterPro:IPR000437; Prok_lipoprot_S. IPR001638; SBP_bac_3. SMART: SM00062; PBPb; 1. TMhelix:1. Signal peptide: present.; Specificity unclear; putative periplasmic-binding protein	3854510..3855544	Azoarcus sp. BH72	4607983
YP_935015.1	CDS	azo3513	NC_008702.1	3855597	3856376	D	Region start changed from 3855391 to 3855571 (-180 bases); putative aliphatic sulfonates transport systemATP-binding protein	3855597..3856376	Azoarcus sp. BH72	4609898
YP_935016.1	CDS	ssuC	NC_008702.1	3856392	3857165	D	Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. Probably responsible for the translocation of the substrate across the membrane.26% Similar to the aliphatic sulfonates permease, ssuC in E.coli. SWISSPROT:SSUC_ECOLI: P75851 InterPro:IPR000515; BPD_transp. Pfam:PF00528; BPD_transp; 1. InterPro:PF00528: Binding-protein-dependent transport systems inner membrane component. TMhelix:6; Specificity unclear; putative aliphatic sulfonates transport systempermease	3856392..3857165	Azoarcus sp. BH72	4607984
YP_935017.1	CDS	azo3515	NC_008702.1	3857523	3857933	R	Putative transcriptional regulatory protein,; Conserved hypothetical protein; putative transcriptional regulator	complement(3857523..3857933)	Azoarcus sp. BH72	4609899
YP_935018.1	CDS	wrbA3	NC_008702.1	3858050	3858604	D	Flavoprotein wrbA3. TREMBL:Q8PGA8: 53% identity,66% similarity. wrbA3 is 26% identical to wrbA1 and 23% identical to wrbA2 InterPro: IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam:PF00258: flavodoxin; TIGR00301: NADP oxidoreductase coenzyme Number of transmembrane helices:0; High confidence in function and specificity; tryptophan repressor binding protein	3858050..3858604	Azoarcus sp. BH72	4607985
YP_935019.1	CDS	azo3517	NC_008702.1	3858601	3860079	R	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase	complement(3858601..3860079)	Azoarcus sp. BH72	4610114
YP_935020.1	CDS	cobD	NC_008702.1	3860126	3861145	D	CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein	3860126..3861145	Azoarcus sp. BH72	4607986
YP_935021.1	CDS	cobC	NC_008702.1	3861138	3862133	D	Cobalamin biosynthesis protein, CobC. CobC is probable involved in the conversion of cobyric acid to cobinamide.Similar to pir|B83486 (48%) and to sprot|COBC_PSEDE (42%). InterPro (PF00155): Aminotransferases class-I and II; Specificity unclear; cobalamin biosynthesis protein	3861138..3862133	Azoarcus sp. BH72	4608502
YP_935022.1	CDS	btuF	NC_008702.1	3862136	3863032	D	Vitamin B12 transport protein btuF precursor. 34% Similar to BtuF from E.coli. Part of the binding-protein-dependent transport system for vitamin B12. Acts with btuCD to transport vitamin B12 across the inner membrane. SWISSPROT:BTUF_ECOLI:P37028 InterPro:IPR002491; Peripla_BP. Pfam: PF01497; Peripla_BP_2; 1. Signal peptide: present. Contains 1 iron siderophore/cobalamin periplasmic- binding domain.; High confidence in function and specificity; putative vitamin B12 transport protein	3862136..3863032	Azoarcus sp. BH72	4608500
YP_935023.1	CDS	azo3521	NC_008702.1	3863039	3864103	R	Conserved hypothetical peptidase. Homology to ebA3686 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA3686(KEGG)) . Pfam: Peptidase family M48. signal peptide. 1 TMHs; Conserved hypothetical protein; peptidase	complement(3863039..3864103)	Azoarcus sp. BH72	4608407
YP_935024.1	CDS	rhlE3	NC_008702.1	3864452	3866065	D	ATP-dependent RNA helicase rhlB (EC 3.6.1.-). Can carry out ATP-dependent unwinding of double stranded RNA. Has a role in RNA decay. Involved in the RNA degradosome a multi-enzyme complex important in RNA processing and messenger RNA degradation.; High confidence in function and specificity; putative ATP-dependent RNA helicase	3864452..3866065	Azoarcus sp. BH72	4607987
YP_935025.1	CDS	leuA2	NC_008702.1	3866142	3867860	R	Alpha-isopropylmalate synthase catalyses the first step in the biosynthesis of leucine, the condensation of acetyl-CoA and alpha- ketoisovalerate to form 2-isopropylmalate synthase. Similar to sprot|LEU1_PSEAE (59%) and to sprot|LE12_RALSO (68%). Pfam (PF00682): HMG-CoA Lyase-like family; High confidence in function and specificity; 2-isopropylmalate synthase	complement(3866142..3867860)	Azoarcus sp. BH72	4609718
YP_935026.1	CDS	azo3524	NC_008702.1	3868239	3868895	R	Conserved hypothetical nitroreductase. Homology to cv1555 of C. violaceum of 72% (trembl|Q7NXS1). Involved in the reduction of nitrogen containing compounds. InterPro: Nitroreductase family (IPR000415). Pfam: Nitroreductase family. no signal peptide. no TMHs; Conserved hypothetical protein; nitroreductase	complement(3868239..3868895)	Azoarcus sp. BH72	4609130
YP_935027.1	CDS	azo3525	NC_008702.1	3868933	3869736	R	TREMBL:Q7NZN8 (43% identity, 53% similarity).; hypothetical protein	complement(3868933..3869736)	Azoarcus sp. BH72	4607988
YP_935028.1	CDS	azo3526	NC_008702.1	3869994	3870761	D	Conserved hypothetical flavoprotein. Homology to tde2498 of T. denticola of 46% (tremblnew|AAS13015). InterPro: Metallo-beta-lactamase superfamily (IPR001279). Pfam: Metallo-beta-lactamase superfamily. no signal peptide. no TMHs; Conserved hypothetical protein; flavoprotein	3869994..3870761	Azoarcus sp. BH72	4607989
YP_935029.1	CDS	azo3527	NC_008702.1	3870767	3872938	D	GGDEF/EAL-domain containing protein; diguanylate cyclase	3870767..3872938	Azoarcus sp. BH72	4607990
YP_935030.1	CDS	azo3528	NC_008702.1	3873423	3874049	D	Conserved hypothetical membrane protein. Homology to blr3274 of B. japonicum of 33% (gnl|keqq|bja:blr3274(KEGG)). Pfam: weak hit to CbiM, an integral membrane protein involved in cobalamin synthesis. TMHMM reporting 5 transmembrane helices. No signal peptide.; Conserved hypothetical protein; hypothetical protein	3873423..3874049	Azoarcus sp. BH72	4607991
YP_935031.1	CDS	azo3529	NC_008702.1	3874055	3874870	D	Probable Precorrin-4 C11-methyltransferase,47% Identity to TrEMBL;Q8GDX1, O26702. SwissProt;O87696. Has PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylases;IPR000878 Cor/por_Metransf; This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function, including P45528. This family includes the methylase Dipthine synthase. Uroporphyrin-III C-methyltransferase (EC: 2.1.1.107) (SUMT)catalyzes the transfer of two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. SUMT is the first enzyme specific to the cobalamin pathway and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430. The sequences of SUMT from a variety of bacterial and archaeal species are currently available. In species such as Bacillus megaterium (gene cobA),Pseudomonas denitrificans (cobA) or Methanobacterium ivanovii (gene corA) SUMT is a protein of about 25 to 30 kD. In Escherichia coli and related bacteria, the cysG protein, which is involved in the biosynthesis of siroheme, is a multifunctional protein composed of a N-terminal domain, probably involved in transforming precorrin-2 into siroheme, and a C-terminal domain which has SUMT activity.; precorrin-4 C(11)-methyltransferase	3874055..3874870	Azoarcus sp. BH72	4607992
YP_935032.1	CDS	cbiX	NC_008702.1	3874867	3875796	D	CbiX conserved hypothetical protein. Function unknown. Cobalamin biosynthesis pathway.; Function unclear; hypothetical protein	3874867..3875796	Azoarcus sp. BH72	4607993
YP_935033.1	CDS	cbiC	NC_008702.1	3875800	3876477	D	Precorrin-8X methylmutase . CATALYZES THE CONVERSION OF PRECORRIN-8X TO HYDROGENOBYRINIC ACID; A Cobalamin biosynthesis precorrin isomerase. METHYL MIGRATION REACTION DURING THE TRANSFORMATION OF PRECORRIN-3 TO FORM COBYRINIC ACID (BY SIMILARITY). InterPro: Precorrin-8X methylmutase CbiC/CobH TIGRFAM: redox_disulf_1: redox-active disulfide; High confidence in function and specificity; precorrin-8X methylmutase	3875800..3876477	Azoarcus sp. BH72	4608435
YP_935034.1	CDS	cbiD	NC_008702.1	3876482	3877690	D	Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase	3876482..3877690	Azoarcus sp. BH72	4608424
YP_935035.1	CDS	cbiE	NC_008702.1	3877680	3878990	D	Precorrin-6 methyltransferase (Precorrin-6Y methylase). CATALYZES THE METHYLATION OF BOTH C-5 AND C-15 IN PRECORRIN-6Y TO FORM PRECORRIN-8X. InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity; precorrin-6Y C(5,15)-methyltransferase	3877680..3878990	Azoarcus sp. BH72	4608425
YP_935036.1	CDS	cbiL	NC_008702.1	3878980	3879933	D	Precorrin-2 C20-methyltransferase (EC 2.1.1.130) (S-adenosyl-L- methionine:precorrin-2 methyltransferase) (SP2MT). METHYLATES PRECORRIN-2 AT THE C-20 POSITION TO PRODUCE PRECORRIN-3A.; High confidence in function and specificity; precorrin-2 C(20)-methyltransferase	3878980..3879933	Azoarcus sp. BH72	4608426
YP_935037.1	CDS	cbiGa	NC_008702.1	3880286	3881062	D	putative Cobalamin (vitamin B12) biosynthesis CbiG protein, truncated. Homology to the N-terminus of cbiG of b. magaterium of 39% (gi|3724046|emb|CAA04315.1|(nr)). Pfam: CibG, CbiG proteins are required for cobalamin (vitamin B 12 ) biosynthesis. IPR012407: Cobalamin (vitamin B12) biosynthesis CbiG. CbiG is one of the enzymes specific to the anaerobic route of cobalamin biosynthesis e.g., in Salmonella typhimurium. While its specific role in this pathway is not known yet, it has been speculated that CbiG may participate in the conversion of cobalt-precorrin 5 into cobalt-precorrin 6. This step requires opening of the delta-lactone ring,excision of acetaldehyde and C-1 methylation. Alternatively, it has been suggested that it may participate in ring contraction. no signal peptide. no TMHs; Function unclear; putative cobalamin (vitamin B12) biosynthesis CbiG protein, truncated	3880286..3881062	Azoarcus sp. BH72	4608431
YP_935038.1	CDS	cbiGb	NC_008702.1	3881071	3881472	D	C-terminal part of CbiG protein. Cobalamin biosynthesis pathway.Precorrin methylase; High confidence in function and specificity; putative cobalamin (vitamin B12) biosynthesis CbiG protein, truncated	3881071..3881472	Azoarcus sp. BH72	4608427
YP_935039.1	CDS	cbiH	NC_008702.1	3881469	3882437	D	Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity; precorrin-3B C(17)-methyltransferase	3881469..3882437	Azoarcus sp. BH72	4608428
YP_935040.1	CDS	azo3538	NC_008702.1	3882434	3882826	D	Conserved hypothetical ferredoxin. Homology to rsp0627 of R. solanacearum of 46% (trembl|Q8XS54). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide. no TMHs; Conserved hypothetical protein; ferredoxin	3882434..3882826	Azoarcus sp. BH72	4608429
YP_935041.1	CDS	azo3539	NC_008702.1	3883237	3883746	R	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs; hypothetical protein	complement(3883237..3883746)	Azoarcus sp. BH72	4607994
YP_935042.1	CDS	azo3540	NC_008702.1	3883931	3885445	D	Conserved hypothetical transcriptional regulatory protein. Homology to rsc0599 of R. solanacearum of 63% (trembl|Q8Y1U0). InterPro: Bacterial regulatory proteins GntR family (IPR000524). Pfam: Bacterial regulatory protein, gntR family; Aminotransferase classI and II. no signal peptide. no TMHs; Conserved hypothetical protein; putative transcriptional regulator	3883931..3885445	Azoarcus sp. BH72	4607995
YP_935043.1	CDS	azo3541	NC_008702.1	3885550	3886434	R	Hypothetical methyltransferase. no Homology of the entire protein with the data bank. Pfam: Putative methyltransferase This is a family of hypothetical proteins which are putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity. Interpro: SAM (and some other nucleotide) binding motif(IPR000051) no signal peptide no TMHs; methyltransferase	complement(3885550..3886434)	Azoarcus sp. BH72	4607996
YP_935044.1	CDS	azo3542	NC_008702.1	3886435	3887310	R	Conserved hypothetical glutathione transferase. Homology to psto0703 of P. syringae of 74% (trembl|Q889P6). Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism Pfam. Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal. no signal peptide. no TMHs; Family membership; glutathione transferase	complement(3886435..3887310)	Azoarcus sp. BH72	4607997
YP_935045.1	CDS	azo3543	NC_008702.1	3887435	3888298	R	Hypothetical secreted protein. No homology of the entire protein to the data bank. Pfam: DUF1555 (domain of unknown function). signal peptide. no TMHs; hypothetical protein	complement(3887435..3888298)	Azoarcus sp. BH72	4607998
YP_935046.1	CDS	azo3544	NC_008702.1	3888597	3889892	D	probable 4-hydroxybutyrate coenzyme A transferase. Homology to cat2 of C. kluyveri of 43% (sprot|CAT2_CLOKL) InterPro: Acetyl-CoA hydrolase/transferase (IPR003702) Pfam: Acetyl-CoA hydrolase/transferase no signal peptide no TMHS; Family membership; 4-hydroxybutyrate CoA-transferase	3888597..3889892	Azoarcus sp. BH72	4607999
YP_935047.1	CDS	yeaS	NC_008702.1	3889954	3890610	D	Conserved hypothetical transport membrane protein. Homology to rsc1520 of R. solanacearum of 59% (trembl|Q8XZ84). Pfam: LysE type translocator. Tigrfam: 2A76: Homoserine/Threonine efflux protein. no signal peptide. probable 6 TMHs; Family membership; leucine export protein LeuE	3889954..3890610	Azoarcus sp. BH72	4608000
YP_935048.1	CDS	ctaQ	NC_008702.1	3890614	3892104	R	Probable carboxypeptidase TAQ. Homology to ctaQ of T. aquaticus of 40% (SWISSPROT:CTAQ_THEAQ) Releases amino acids sequentially from the C-terminus with a broad substrate specificity (except for proline). Pfam: carboxypeptidas Taq (M32) metallopep no signal peptide no TMHs; Family membership; carboxypeptidase TAQ	complement(3890614..3892104)	Azoarcus sp. BH72	4610166
YP_935049.1	CDS	azo3547	NC_008702.1	3892274	3892729	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. signal peptide present.; hypothetical protein	3892274..3892729	Azoarcus sp. BH72	4608540
YP_935050.1	CDS	azo3548	NC_008702.1	3892726	3893553	D	Conserved hypothetical secreted protein. Homology to cv0063 of C. violaceum of 41% (trembl|Q7P1Z9(SRS)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	3892726..3893553	Azoarcus sp. BH72	4608001
YP_935051.1	CDS	psd	NC_008702.1	3893550	3894416	R	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase	complement(3893550..3894416)	Azoarcus sp. BH72	4608002
YP_935052.1	CDS	cobB	NC_008702.1	3894532	3895827	R	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase	complement(3894532..3895827)	Azoarcus sp. BH72	4609638
YP_935053.1	CDS	cobA2	NC_008702.1	3895824	3896717	R	Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; uroporphyrin-III C-methyltransferase	complement(3895824..3896717)	Azoarcus sp. BH72	4608499
YP_935054.1	CDS	cobO	NC_008702.1	3896722	3897342	R	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase	complement(3896722..3897342)	Azoarcus sp. BH72	4608498
YP_935055.1	CDS	azo3553	NC_008702.1	3897371	3898168	R	37% Similar to the iron(III)-hydroxamate transport membrane protein, fhuC in E.coli.Part of the ABC transporter complex fhuACDB involved in iron(III)-hydroxamate import. Probably responsible for energy coupling to the transport system. SWISSPROT:FHUC_ECOLI:P07821 InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1.; High confidence in function and specificity; putative ABC-type transporter ATPase component	complement(3897371..3898168)	Azoarcus sp. BH72	4608503
YP_935056.1	CDS	azo3554	NC_008702.1	3898168	3899148	R	Region start changed from 3899167 to 3899122 (-45 bases); putative ABC transporter system, permease	complement(3898168..3899148)	Azoarcus sp. BH72	4608003
YP_935057.1	CDS	azo3555	NC_008702.1	3899200	3901071	R	COBALAMIN RECEPTOR PROTEIN.; Specificity unclear; TonB-dependent receptor	complement(3899200..3901071)	Azoarcus sp. BH72	4608004
YP_935058.1	CDS	azo3556	NC_008702.1	3901150	3903090	R	Putative outer membrane TonB-dependent receptor,probably involved in iron metabolism. 20% Similar to the IrgA enterobactine outer membrane receptor in V. cholerae. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC VIBRIOBACTIN AN IRON CHELATIN SIDEROPHORE THAT ALLOWS V.CHOLERAE TO EXTRACT IRON FROM THE ENVIRONMENT. SWISSPROT:IRGA_VIBCH:P27772. 21% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1.; Specificity unclear; putative TonB-dependent receptor	complement(3901150..3903090)	Azoarcus sp. BH72	4608005
YP_935059.1	CDS	cobU	NC_008702.1	3903450	3904043	D	Bifunctional cobalamin biosynthesis protein cobU [Includes: Cobinamide kinase; Cobinamide phosphate guanylyltransferase]. ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate. InterPro: Cobalbumin biosynthesis enzyme; High confidence in function and specificity; cobinamide kinase/cobinamide phosphate guanylyltransferase	3903450..3904043	Azoarcus sp. BH72	4608006
YP_935060.1	CDS	azo3558	NC_008702.1	3904044	3905105	R	Conserved hypothetical membrane protein. Homology to gsu0462 of G. sulfurreducens of 41% (AAR33794). probable 2 TMHs. no signal peptide. No domains predicted.; Conserved hypothetical protein; hypothetical protein	complement(3904044..3905105)	Azoarcus sp. BH72	4608506
YP_935061.1	CDS	azo3559	NC_008702.1	3905102	3906664	R	Hypothetical membrane protein. No homology of the whole protein to the data bank. Has PF05987, Bacterial protein of unknown function (DUF898);IPR010295 ; This family consists of several bacterial proteins of unknown function. Some of the family members are described as putative membrane proteins. No signal peptide 6 TMHs; hypothetical protein	complement(3905102..3906664)	Azoarcus sp. BH72	4608007
YP_935062.1	CDS	cobT	NC_008702.1	3906932	3907978	D	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	3906932..3907978	Azoarcus sp. BH72	4608008
YP_935063.1	CDS	cobS	NC_008702.1	3907990	3908760	D	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase	3907990..3908760	Azoarcus sp. BH72	4608505
YP_935064.1	CDS	azo3562	NC_008702.1	3908745	3909296	D	Alpha-ribazole-5-phosphate phosphatase. Converts N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6-dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin. 27% PG/BPGM_mutase. Pfam:PF00300; PGAM; 1.; High confidence in function and specificity; putative alpha-ribazole phosphatase	3908745..3909296	Azoarcus sp. BH72	4608504
YP_935065.1	CDS	waaE2	NC_008702.1	3909437	3910396	D	ADP-heptose synthase (EC 2.7.-.-).; High confidence in function and specificity; ADP-heptose synthase	3909437..3910396	Azoarcus sp. BH72	4608009
YP_935066.1	CDS	rfaD	NC_008702.1	3910439	3911416	D	59% Epimerase_Dh.IPR000205; NAD_BS. Pfam:PF01370; Epimerase; 1. Non-secretory protein.; High confidence in function and specificity; putative ADP-L-glycero-D-mannoheptose-6-epimerase	3910439..3911416	Azoarcus sp. BH72	4610104
YP_935067.1	CDS	waaF2	NC_008702.1	3911413	3912468	D	ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-).; High confidence in function and specificity; ADP-heptose--LPS heptosyltransferase II	3911413..3912468	Azoarcus sp. BH72	4609715
YP_935068.1	CDS	waaC2	NC_008702.1	3912476	3913567	D	Lipopolysaccharide heptosyltransferase-1 (EC 2.-.-.-). HEPTOSE TRANSFER TO THE LIPOPOLYSACCHARIDE CORE. IT TRANSFERS THE INNNERMOST HEPTOSE TO [4-P](3-DEOXY-D-MANNO-OCTULOSONIC ACID)2-IVA. S18: ribosomal protein S18; High confidence in function and specificity; lipopolysaccharide heptosyltransferase I	3912476..3913567	Azoarcus sp. BH72	4610106
YP_935069.1	CDS	azo3567	NC_008702.1	3913567	3914700	D	Region start changed from 3913496 to 3913541 (-45 bases); glucosyltransferase I	3913567..3914700	Azoarcus sp. BH72	4610102
YP_935070.1	CDS	waaP1	NC_008702.1	3914697	3915533	D	Lipopolysaccharide core biosynthesis protein rfaP. Specific function unclear. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE.; lipopolysaccharide core biosynthesis protein	3914697..3915533	Azoarcus sp. BH72	4608010
YP_935071.1	CDS	waaP2	NC_008702.1	3915530	3916279	D	Lipopolysaccharide core biosynthesis protein rfaP. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.; lipopolysaccharide core biosynthesis protein	3915530..3916279	Azoarcus sp. BH72	4610107
YP_935072.1	CDS	waaP3	NC_008702.1	3916293	3917066	D	Lipopolysaccharide core biosynthesis protein. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.; lipopolysaccharide core biosynthesis protein	3916293..3917066	Azoarcus sp. BH72	4610108
YP_935073.1	CDS	azo3571	NC_008702.1	3917063	3918520	D	InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster.; hypothetical protein	3917063..3918520	Azoarcus sp. BH72	4610109
YP_935074.1	CDS	msbA2	NC_008702.1	3918579	3920381	R	Lipid A export ATP-binding protein msbA. MsbA (TC 3.A.1.106.1) is involved in lipid A and possibly also glycerophospholipids export. The transmembrane domain (TMD) forms a pore in the inner membrane and the ATP-binding domain (NBD) is responible for energy generation. Similar to TREMBL:Q9HUG8; TREMBL:Q88D92; SWISSPROT:P60752 (39% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting five transmembrane helices. TC (3.A.1.106): The Lipid Exporter (LipidE) Family.; High confidence in function and specificity; lipid A export ATP-binding/permease	complement(3918579..3920381)	Azoarcus sp. BH72	4608011
YP_935075.1	CDS	azo3573	NC_008702.1	3920557	3921198	D	Conserved hypothetical protein, 43% identity(65% similarity) to TrEMBL|Q9HUG7,Hypothetical protein PA4998 [PA4998] [Pseudomonas aeruginosa]. Has PF06293:IPR010440:Lipopolysaccharide kinase (Kdo/WaaP) family;These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. enterica. No Signal Peptide or TMH reported present.; hypothetical protein	3920557..3921198	Azoarcus sp. BH72	4609276
YP_935076.1	CDS	azo3574	NC_008702.1	3921206	3922345	R	Hypothetical membrane protein. Homology to pspto4986 of P. syringae of 28% (trembl|Q87VF1(SRS)) No domains predicted signal peptide 9 TMHs; hypothetical protein	complement(3921206..3922345)	Azoarcus sp. BH72	4608012
YP_935077.1	CDS	azo3575	NC_008702.1	3922367	3923167	R	Family membership; pyruvyltransferase	complement(3922367..3923167)	Azoarcus sp. BH72	4608013
YP_935078.1	CDS	azo3576	NC_008702.1	3923220	3924176	R	hypothetical protein	complement(3923220..3924176)	Azoarcus sp. BH72	4608014
YP_935079.1	CDS	azo3577	NC_008702.1	3924173	3925075	R	Possibly related to cell surface polysaccharide biosynthesis, due to the presence of the gene in a polysaccharide synthesis gene cluster.; hypothetical protein	complement(3924173..3925075)	Azoarcus sp. BH72	4608015
YP_935080.1	CDS	azo3578	NC_008702.1	3925072	3926202	R	Specificity unclear; glycosyltransferase	complement(3925072..3926202)	Azoarcus sp. BH72	4608016
YP_935081.1	CDS	nolU	NC_008702.1	3926195	3927979	R	Putative carbamoyltransferase. Homology to nolU of Rhizobium sp. NGR234 of 33% InterPro: Carbamoyltransferase Pfam: Carbamoyltransferase no signal peptide no TMHs; Family membership; putative carbamoyltransferase	complement(3926195..3927979)	Azoarcus sp. BH72	4608017
YP_935082.1	CDS	azo3580	NC_008702.1	3928043	3930106	R	Catalysis of the reactions of the type: acyl-carrier + reactant = acyl-reactant + carrier. Entry name : Q888M0 InterPro : IPR002656; Acyl_transf_3. Identity: 227/677 (33%) Pfam PF01757; Acyl_transf_3; 1. Prediction: Non-secretory protein Signal peptide probability: 0.005(almost Yes) Number of predicted TMHs: 10; Family membership; putative acyltransferase family protein	complement(3928043..3930106)	Azoarcus sp. BH72	4609394
YP_935083.1	CDS	capD	NC_008702.1	3930274	3932139	R	48% Polysac_CapD. Pfam:PF02719; Polysacc_synt_2; 1.; High confidence in function and specificity; putative capsular polysaccharide biosynthesis protein	complement(3930274..3932139)	Azoarcus sp. BH72	4608018
YP_935084.1	CDS	azo3582	NC_008702.1	3932553	3933590	R	Similar to proteins annotated as phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP- MurNAc-pentapeptide phosphotransferase). First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity).; Function unclear; cell envelope biogenesis membrane protein	complement(3932553..3933590)	Azoarcus sp. BH72	4608413
YP_935085.1	CDS	wbpV	NC_008702.1	3933587	3934570	R	50%; High confidence in function and specificity; putative UDP-glucose 4-epimerase	complement(3933587..3934570)	Azoarcus sp. BH72	4608019
YP_935086.1	CDS	azo3584	NC_008702.1	3934567	3935748	R	InterPro: Glycosyl transferases group 1; Specificity unclear; glycosyltransferase	complement(3934567..3935748)	Azoarcus sp. BH72	4610111
YP_935087.1	CDS	azo3585	NC_008702.1	3935717	3936460	R	Putative glycosyl transferase MJ1057 (EC 2.-.-.-). InterPro: Glycosyl transferase family 2; Family membership; glycosyltransferase	complement(3935717..3936460)	Azoarcus sp. BH72	4608020
YP_935088.1	CDS	fcl1	NC_008702.1	3936457	3937452	R	GDP-L-fucose synthetase (GDP-4-keto-6-deoxy-D-mannose-35-epimerase -4-reductase). Two step NADP-dependent conversion of GDP-4-dehydro-6- deoxy-D-mannose to GDP-fucose involving an epimerase and a reductase reaction.54% ADH_short.IPR001509; Epimerase_Dh. Pfam:PF01370; Epimerase. Non-secretory protein.; High confidence in function and specificity; putative GDP-fucose synthetase	complement(3936457..3937452)	Azoarcus sp. BH72	4608021
YP_935089.1	CDS	gmd	NC_008702.1	3937403	3938488	R	[EC:4.2.1.47] , GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)., GDP-mannose 4,6-dehydratase, NAD dependent epimerase/dehydratase family,gmd: GDP-mannose 4,6-dehydratase; High confidence in function and specificity; GDP-mannose 4,6-dehydratase	complement(3937403..3938488)	Azoarcus sp. BH72	4608737
YP_935090.1	CDS	azo3588	NC_008702.1	3938557	3940620	R	Hypothetical membrane protein. No homology to the data bank. No domains predicted. no signal peptide. 9 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3938557..3940620)	Azoarcus sp. BH72	4608926
YP_935091.1	CDS	azo3589	NC_008702.1	3940575	3941408	R	InterPro: Glycosyl transferase family 2. Slight similarity to dolicholphosphate mannosyltransferases,might therefore transfer a sugar moiety directly to a lipid carrier.; Specificity unclear; glycosyltransferase	complement(3940575..3941408)	Azoarcus sp. BH72	4608022
YP_935092.1	CDS	emrE	NC_008702.1	3941422	3941778	R	Low similarity with the EmrE protein (Methyl viologen resistance protein C)(Ethidium resistance protein)in E.coli. Multidrug transporter. Confers resistance to a wide range of toxic compounds by removing them for the cells. The efflux is coupled to an influx of protons. Probably prevents the incorporation of methyl viologen into cells. Involved in ethidium bromide efflux. EMRE_ECOLI:P23895. InterPro:IPR000390; Smr. Pfam: PF00893; Multi_Drug_Res; 1. Signal peptide present. TMHelix: 4.; High confidence in function and specificity; multidrug efflux transporter protein	complement(3941422..3941778)	Azoarcus sp. BH72	4608023
YP_935093.1	CDS	azo3591	NC_008702.1	3941775	3942605	R	Family membership; sugar or sugar nucleotide oxidoreductase	complement(3941775..3942605)	Azoarcus sp. BH72	4608666
YP_935094.1	CDS	azo3592	NC_008702.1	3942602	3943387	R	Gene located in a gene cluster related to an unidentified cell surface polysaccharide; hypothetical protein	complement(3942602..3943387)	Azoarcus sp. BH72	4608024
YP_935095.1	CDS	azo3593	NC_008702.1	3943384	3944523	R	Hypothetical membrane protein. No good homology of the entire protein with the data bank. No domains predicted. No signal peptide. 1 TMH; hypothetical protein	complement(3943384..3944523)	Azoarcus sp. BH72	4608025
YP_935096.1	CDS	azo3594	NC_008702.1	3944541	3945566	R	Putative glycosyl transferase sll0501 (EC 2.-.-.-).; Specificity unclear; glycosyltransferase	complement(3944541..3945566)	Azoarcus sp. BH72	4608026
YP_935097.1	CDS	azo3595	NC_008702.1	3945793	3948288	R	hypothetical protein	complement(3945793..3948288)	Azoarcus sp. BH72	4608027
YP_935098.1	CDS	wzt	NC_008702.1	3948285	3949694	R	44% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom:PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 1.; putative polysaccharide export transport system ATP-binding protein	complement(3948285..3949694)	Azoarcus sp. BH72	4608028
YP_935099.1	CDS	wzm	NC_008702.1	3949684	3950472	R	51% ABC_transpt2. Pfam:PF01061; ABC2_membrane; 1. TMhelix:6. Non-secretory protein.; Specificity unclear; putative ABC polysaccharide exporter permease	complement(3949684..3950472)	Azoarcus sp. BH72	4610121
YP_935100.1	CDS	azo3598	NC_008702.1	3950578	3952557	R	Possibly related to cell surface biosynthesis, ue to the location of he gene in a polysaccharide synthesis gene cluster.; hypothetical protein	complement(3950578..3952557)	Azoarcus sp. BH72	4610120
YP_935101.1	CDS	fcl2	NC_008702.1	3952636	3953631	R	49%; High confidence in function and specificity; putative GDP-fucose synthetase	complement(3952636..3953631)	Azoarcus sp. BH72	4608029
YP_935102.1	CDS	polA	NC_008702.1	3953917	3956673	R	DNA polymerase I (EC 2.7.7.7) (POL I). IN ADDITION TO POLYMERASE ACTIVITY THIS DNA POLYMERASE EXHIBITS 3 TO 5 AND 5 TO 3 EXONUCLEASE ACTIVITY. IT IS ABLE TO UTILIZE NICKED CIRCULAR DUPLEX DNA AS A TEMPLATE AND CAN UNWIND THE PARENTAL DNA STRAND FROM ITS TEMPLATE. InterPro: Replicative DNA polymerase; High confidence in function and specificity; DNA polymerase I	complement(3953917..3956673)	Azoarcus sp. BH72	4608738
YP_935103.1	CDS	azo3601	NC_008702.1	3956755	3957477	D	Hypothetical protein PA4923. TREMBL:Q82UL5: 68% identity, 82% similarity InterPro:IPR005269; Cons_hypoth730. Pfam:PF03641; Lysine_decarbox; 1. TIGRFAMs:TIGR00730; Cons_hypoth730 bcl-2: Apoptosis regulator Non-secretory protein with signal peptide probability 0(Signal P predicted9 Absence of transmembrane helices (TMHHH predicted); Function unclear; hypothetical protein	3956755..3957477	Azoarcus sp. BH72	4609596
YP_935104.1	CDS	azo3602	NC_008702.1	3957597	3957920	D	Conserved hypothetical secreted protein. Homology to CV0777 of C.violaceum of 42% (trembl|Q7NZZ2(SRS)). No domains predicted. Signal peptide present. No TMH reported.; Conserved hypothetical protein; hypothetical protein	3957597..3957920	Azoarcus sp. BH72	4608030
YP_935105.1	CDS	azo3603	NC_008702.1	3957899	3958459	D	hypothetical protein	3957899..3958459	Azoarcus sp. BH72	4608031
YP_935106.1	CDS	thrB	NC_008702.1	3958480	3959433	D	catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase	3958480..3959433	Azoarcus sp. BH72	4608032
YP_935107.1	CDS	azo3605	NC_008702.1	3959528	3960298	D	Conserved hypothetical membrane protein. Homology to cv0192 of C. violaceum of 32% (trembl|Q7P1M1(SRS)). No domains predicted. No signal peptide. 6 TMHs.; Conserved hypothetical protein; hypothetical protein	3959528..3960298	Azoarcus sp. BH72	4609943
YP_935108.1	CDS	azo3606	NC_008702.1	3960306	3961076	D	Conserved hypothetical protein. Homology to ne1472 of N. europaea of 33% (trembl|Q82UL2(SRS)). No domains predicted. No signal peptide. 6 TMHs.; hypothetical protein	3960306..3961076	Azoarcus sp. BH72	4608033
YP_935109.1	CDS	nadD	NC_008702.1	3961057	3961740	D	Probable nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) (Deamido-NAD(+) diphosphorylase) (Nicotinate mononucleotide adenylyltransferase) (NaMN adenylyltransferase). Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity). InterPro: Cytidylyltransferase; High confidence in function and specificity; nicotinate-nucleotide adenylyltransferase	3961057..3961740	Azoarcus sp. BH72	4608034
YP_935110.1	CDS	azo3608	NC_008702.1	3961760	3962125	D	Conserved hypothetical protein. Homology to NE0358 of Nitrosomonas europaea of 55% (trembl:Q82XC6). Pfam:Domain of unknown function DUF143. This domain has no known function nor do any of the proteins that possess it. The aligned region is approximately 100 amino acids long. Tigrfam: TIGR00090 iojap-related protein. This model describes a strictly bacterial family of proteins related to iojap from plants. The gene iojap is a pattern-striping gene in maize, reflecting a chloroplast development defect in some cells. Maize has two RNA polymerases in plastids,but the plastid-encoded one; hypothetical protein	3961760..3962125	Azoarcus sp. BH72	4609305
YP_935111.1	CDS	azo3609	NC_008702.1	3962122	3962592	D	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase	3962122..3962592	Azoarcus sp. BH72	4608035
YP_935112.1	CDS	def2	NC_008702.1	3962595	3963128	D	Probable peptide deformylase (EC 3.5.1.88). Homology to def of E. coli of 42% (sprot|DEF_ECOLI(SRS)). Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions Interpro: Formylmethionine deformylase (IPR000181) Pfam: Polypeptide deformylase Tigrfam: pept_deformyl: polypeptide deformylase no signal peptide no TMHs; High confidence in function and specificity; peptide deformylase	3962595..3963128	Azoarcus sp. BH72	4608036
YP_935113.1	CDS	azo3611	NC_008702.1	3963195	3963815	D	Homology to Maf-like proteins; Family membership; Maf-like protein	3963195..3963815	Azoarcus sp. BH72	4608617
YP_935114.1	CDS	cafA	NC_008702.1	3963871	3965382	D	Ribonuclease G (EC 3.1.4.-) (RNase G) (Cytoplasmic axial filament protein). INVOLVED IN PROCESSING OF THE 5END OF 16S RRNA. COULD BE INVOLVED IN CHROMOSOME SEGREGATION AND CELL DIVISION. IT MAY BE ONE OF THE COMPONENTS OF THE CYTOPLASMIC AXIAL FILAMENTS BUNDLES OR MERELY REGULATE THE FORMATION OF THIS STRUCTURE.; Family membership; putative ribonuclease	3963871..3965382	Azoarcus sp. BH72	4608037
YP_935115.1	CDS	menA	NC_008702.1	3965391	3966347	D	Probable 14-dihydroxy-2-naphthoate octaprenyltransferase (EC 2.5.1.-) (DHNA-octaprenyltransferase). CONVERSION OF 1,4-DIHYDROXY-2-NAPHTHOATE (DHNA) TO DIMETHYLMENAQUINONE (DMK). ATTACHES OCTAPRENYLPYROPHOSPHATE A MEMBRANE-BOUND 40-CARBON SIDE CHAIN TO DHNA. THE CONVERSION OF DHNA TO DMK PROCEEDS IN THREE STAGES: THE REMOVAL OF THE CARBOXYL GROUP OF DHNA AS CO2 THE ATTACHMENT OF THE ISOPRENOID SIDE CHAIN AND A QUINOL-TO-QUINONE OXIDATION WHICH IS THOUGHT TO BE SPONTANEOUS (BY SIMILARITY). TIGRFAM: menA: 14-dihydroxy-2-naphthoate octaprenyltransferase; Specificity unclear; 1,4-dihydroxy-2-naphthoate octaprenyltransferase	3965391..3966347	Azoarcus sp. BH72	4608410
YP_935116.1	CDS	azo3614	NC_008702.1	3966362	3966727	R	Conserved hypothetical membrane protein. Homology to PA0359 of Pseudomonas aeruginosa of 35% (trembl|Q9I6D5(SRS)). No domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein; hypothetical protein	complement(3966362..3966727)	Azoarcus sp. BH72	4609207
YP_935117.1	CDS	ompR3	NC_008702.1	3966875	3967591	D	Transcriptional regulatory protein, Trans_reg_C. IPR001789 Response_reg. Pfam: PF00486; trans_reg_C. PF00072 response_reg. SMART: SM00448 REC.; Specificity unclear; DNA-binding response regulator	3966875..3967591	Azoarcus sp. BH72	4608038
YP_935118.1	CDS	envZ3	NC_008702.1	3967591	3968691	D	Putative sensor histidine kinase, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR009082; His_kin_homodim. IPR003660; HAMP. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. TMHMM reporting 2 transmembrane helices.; Specificity unclear; putative sensor histidine kinase	3967591..3968691	Azoarcus sp. BH72	4609448
YP_935119.1	CDS	azo3617	NC_008702.1	3968809	3969477	D	Putative calcium binding protein,40% similarity to TrEMBL;O22845. Has 3 EFh|EF-hand, calcium binding motif;(SMART|SM00054):Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand. This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain. In an EF-hand loop the calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X and -Z. The invariant Glu or Asp at position 12 provides two oxygens for liganding Ca (bidentate ligand). NO Signal peptide or TMh reported present.; Family membership; putative calcium binding protein	3968809..3969477	Azoarcus sp. BH72	4608673
YP_935120.1	CDS	gcvA	NC_008702.1	3969509	3970477	R	Glycine cleavage system transcriptional activator (Gcv operon activator). Regulatory protein for the glycine cleavage system operon (gcv). Mediates activation og gcv by glycine and repression by purines. GcvA is negatively autoregulated. Bind to three sites upstream of the gcv promoter. Similar to SWISSPROT: sprot|GCVA_ECOLI (39% Escherichia coli, glycine cleavage system transcriptional activator (gcv operon activator)) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; glycine cleavage system transcriptional activator	complement(3969509..3970477)	Azoarcus sp. BH72	4608039
YP_935121.1	CDS	azo3619	NC_008702.1	3970592	3970765	D	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	3970592..3970765	Azoarcus sp. BH72	4608869
YP_935122.1	CDS	azo3620	NC_008702.1	3970934	3971842	R	Putative adenylate/ guanylate cyclase,; Function unclear; putative adenylate/guanylate cyclase	complement(3970934..3971842)	Azoarcus sp. BH72	4608040
YP_935123.1	CDS	tag	NC_008702.1	3971984	3972556	R	DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I) . HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity; DNA-3-methyladenine glycosidase I	complement(3971984..3972556)	Azoarcus sp. BH72	4608041
YP_935124.1	CDS	ptxR	NC_008702.1	3972582	3973490	R	Probable transcriptional regulator, LysR family,; Family membership; LysR family transcriptional regulator	complement(3972582..3973490)	Azoarcus sp. BH72	4609912
YP_935125.1	CDS	adhC	NC_008702.1	3973580	3974692	D	Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity; alcohol dehydrogenase classIII	3973580..3974692	Azoarcus sp. BH72	4609653
YP_935126.1	CDS	azo3624	NC_008702.1	3974733	3975587	D	TREMBL:Q88ME4: 72% identity,83% similarity Esterase D (EC 3.1.1.1). This family contains several seemingly unrelated proteins, including human esterase D; mycobacterial antigen 85, which is responsible for the high affinity of mycobacteria to fibronectin; Corynebacterium glutamicum major secreted protein PS1; and hypothetical proteins from Escherichia coli, yeast,mycobacteria and Haemophilus influenzae. InterPro:IPR000801; Esterase_put. IPR000379; Ser_estrs. Pfam: PF00756; Esterase; InterPro: Putative esterase Absence of signal peptide and transmembrane helices; Specificity unclear; esterase	3974733..3975587	Azoarcus sp. BH72	4608280
YP_935127.1	CDS	azo3625	NC_008702.1	3975594	3976508	R	Hypothetical membrane protein. no homology to the data bank no doamains predicted no signal peptide 1 TMH; hypothetical protein	complement(3975594..3976508)	Azoarcus sp. BH72	4608042
YP_935128.1	CDS	azo3626	NC_008702.1	3976698	3977960	D	Conserved hypothetical chaperon protein: Homology to cv2395 of C. violaceum of 62% (trembl|Q7NVE8). InterPro: Heat shock protein hsp70 (IPR001023). Pfam: Hsp70 protein. no signal peptide. no TMHs; Family membership; chaperon protein	3976698..3977960	Azoarcus sp. BH72	4608043
YP_935129.1	CDS	azo3627	NC_008702.1	3978018	3978974	R	Conserved hypothetical SLT domain protein. Homology to NE2226 of N.europaea of 42% (trembl|Q82SS9(SRS). Pfam: Transglycosylase SLT domain. Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4- glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation of a 1,6-anhydrobond in the muramic acid residue. Escherichia coli has at least three different lytic transglycosylases: two soluble isozymes of 65 Kd and 35 Kd and a membrane-bound enzyme of 38 Kd. The sequence of the 65 Kd enzyme (gene slt) has been determined. A domain of about 90 residues located near the C-terminal section of slt was recently shown to be present in a number of other prokaryotic and phage proteins. This SLT domain shared by these proteins is involved in catalytic activity. The most conserved part of this domain contains the contains two conserved serines and a glutamate which form part of this active site signature. no TMHs. signal peptide; Conserved hypothetical protein; hypothetical protein	complement(3978018..3978974)	Azoarcus sp. BH72	4608044
YP_935130.1	CDS	azo3628	NC_008702.1	3979292	3979768	D	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	3979292..3979768	Azoarcus sp. BH72	4608045
YP_935131.1	CDS	crgA	NC_008702.1	3979900	3980787	R	Transcriptional regulator, LysR family,; High confidence in function and specificity; LysR family transcriptional regulator	complement(3979900..3980787)	Azoarcus sp. BH72	4608046
YP_935132.1	CDS	ydeA	NC_008702.1	3980888	3982096	D	Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12.; Specificity unclear; putative transmembrane efflux protein	3980888..3982096	Azoarcus sp. BH72	4608533
YP_935133.1	CDS	yafB	NC_008702.1	3982119	3982925	D	25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin synthase beta subunit No signal peptide (non secretory protein) predicted by Signal P and no transmembrane helices (predicted by TMHMM).; High confidence in function and specificity; 2,5-diketo-D-gluconate reductase B	3982119..3982925	Azoarcus sp. BH72	4610164
YP_935134.1	CDS	azo3632	NC_008702.1	3982978	3984780	D	ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR001140): ABC transportertransmembrane region. Pfam (PF00664): ABC transporter transmembrane region. Pfam (PF00005): ABC transporter. TMHMM reporting six transmembrane helices. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily.; High confidence in function and specificity; ABC transporter permease and ATP-binding protein	3982978..3984780	Azoarcus sp. BH72	4610138
YP_935135.1	CDS	azo3633	NC_008702.1	3985096	3985944	D	Hypothetical secreted protein. No significant homology over the entier protein. signal peptide no TMHs; hypothetical protein	3985096..3985944	Azoarcus sp. BH72	4608047
YP_935136.1	CDS	azo3634	NC_008702.1	3986061	3988160	R	Probable D-(-)-3-hydroxybutyrate oligomer hydrolase. Homology to a orf of Ralstonia pickettii of 48% (gi|2154711|dbj|BAA20331.1|(NCBI ENTREZ)). Catalysis of the reaction: (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate. No doamis predicted. Signal peptide. TMHs in signal peptide.,; Family membership; D-(-)-3-hydroxybutyrate oligomer hydrolase	complement(3986061..3988160)	Azoarcus sp. BH72	4608048
YP_935137.1	CDS	azo3635	NC_008702.1	3988511	3989053	D	Conserved hypothetical acetyltransferase. Homology to cv2337 of C. violaceum of 43% (AAQ60009). InterPro: GCN5-related N-acetyltransferase (IPR000182). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Conserved hypothetical protein; acetyltransferase	3988511..3989053	Azoarcus sp. BH72	4608049
YP_935138.1	CDS	glmS	NC_008702.1	3989120	3990949	R	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Hexosephosphate aminotransferase) (D-fructose-6- phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase). Catalyzes the first step in hexosamine metabolism converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity). InterPro: Glutamine amidotransferase class-II TIGR00274: glucokinase regulator-rela; High confidence in function and specificity; glucosamine-fructose-6-phosphate aminotransferase	complement(3989120..3990949)	Azoarcus sp. BH72	4608050
YP_935139.1	CDS	glmU	NC_008702.1	3990992	3992350	R	Bifunctional glmU protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.57)]. Bifunctional enzyme responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and the synthesis of UDP-GlcNAc. InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-e; High confidence in function and specificity; UDP-N-acetylglucosamine pyrophosphorylase/diamine N-acetyltransferase	complement(3990992..3992350)	Azoarcus sp. BH72	4608892
YP_935140.1	CDS	pta	NC_008702.1	3992536	3993945	D	Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein; bifunctional enoyl-CoA hydratase/phosphate acetyltransferase	3992536..3993945	Azoarcus sp. BH72	4608893
YP_935141.1	CDS	ackA	NC_008702.1	3993942	3995129	D	probable acetate kinase. Homology to ackA of s. meliloti of 46% (sprot|ACK2_RHIME) Acetate kinase is involved in the activation of acetate to acetyl CoA and in the secretion of acetate. It catalyzes the reaction ATP + acetate = ADP + acetyl phosphate. InterPro: Acetate kinase (IPR004372); acetate and butyrate kinase (IPR000890) Pfam: Acetokinase family Tigrfam: ackA: acetate kinase no singal peptide no TMHs; High confidence in function and specificity; acetate kinase	3993942..3995129	Azoarcus sp. BH72	4609645
YP_935142.1	CDS	azo3640	NC_008702.1	3995147	3995914	R	Conserved hypothetical membrane protein. TREMBL:Q9A2S0: 40% identity InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81. Non secretory protein (signal peptide probablity:0.035) and presence of 7 transmembrane helices (TMHMM predicted).; Conserved hypothetical protein; hypothetical protein	complement(3995147..3995914)	Azoarcus sp. BH72	4608262
YP_935143.1	CDS	gltD	NC_008702.1	3996223	3997689	R	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta	complement(3996223..3997689)	Azoarcus sp. BH72	4608051
YP_935144.1	CDS	gltB	NC_008702.1	3997694	4002367	R	Ferredoxin-dependent glutamate synthase,; Specificity unclear; ferredoxin-dependent glutamate synthase	complement(3997694..4002367)	Azoarcus sp. BH72	4608916
YP_935145.1	CDS	azo3643	NC_008702.1	4002629	4003768	R	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein	complement(4002629..4003768)	Azoarcus sp. BH72	4608915
YP_935146.1	CDS	aroB	NC_008702.1	4003759	4004841	R	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase	complement(4003759..4004841)	Azoarcus sp. BH72	4608052
YP_935147.1	CDS	aroK	NC_008702.1	4004829	4005365	R	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase	complement(4004829..4005365)	Azoarcus sp. BH72	4608343
YP_935148.1	CDS	pilQ	NC_008702.1	4005442	4007565	R	Type 4 fimbrial biogenesis protein PilQ, similarity to sprot|PILQ_PSEAE (41%) and trembl|Q8XV60 (45%). PilQ is essential for the biogenesis of type IV pili. Its precise function is unknown, but it has been suggested that it may act as a pilus channel in the final stages of pilus assembly. InterPro (PF00263): General (type II) secretion pathway (GSP) D protein SignalP reporting signal peptide.; Specificity unclear; type 4 fimbrial biogenesis protein	complement(4005442..4007565)	Azoarcus sp. BH72	4608348
YP_935149.1	CDS	pilP	NC_008702.1	4007562	4008077	R	Type 4 fimbrial biogenesis protein, PilP. PilP is essential for the biogenesis of type IV pili. Similar to trembl|Q7NZU1(37%). SignalP reporting Signal Peptide.; Family membership; putative type 4 fimbrial biogenesis protein	complement(4007562..4008077)	Azoarcus sp. BH72	4609570
YP_935150.1	CDS	pilO	NC_008702.1	4008074	4008748	R	Type 4 fimbrial biogenesis protein PilO, similarity to pir|S77728 (40%). PilO proteins are involved in the assembly of pilin. TMHMM reporting one TMH.; Specificity unclear; type 4 fimbrial biogenesis protein	complement(4008074..4008748)	Azoarcus sp. BH72	4609569
YP_935151.1	CDS	pilN	NC_008702.1	4008745	4009344	R	Type 4 fimbrial biogenesis protein PilN, similarity to trembl|Q82SK2(51%)and to pir|S77727(42%). In P. aeruginosa PilN was found to be required for fimbrial biogenesis by complementation studies using twitching motility and sensitivity to fimbrial-specific phage as indicators of the presence of functional fimbriae. SignalP reporting signal peptide.; Specificity unclear; type 4 fimbrial biogenesis protein	complement(4008745..4009344)	Azoarcus sp. BH72	4609568
YP_935152.1	CDS	pilM	NC_008702.1	4009341	4010417	R	Type 4 fimbrial biogenesis protein PilM, similarity to trembl|Q82SK1 (56%)and to pir|S77726 (47%). Four genes,pilM-P, encode the necessary proteins and pilM is required for the assembly of the type IV fimbriae in Pseudomonas aeruginosa.; Specificity unclear; type 4 fimbrial biogenesis protein	complement(4009341..4010417)	Azoarcus sp. BH72	4609567
YP_935153.1	CDS	mrcA	NC_008702.1	4010609	4012981	D	Probable penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin- insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]. Homology to mrcA of N. meningitides of 47% (sprot|PBPA_NEIMA(SRS)) Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity). InterPro: Penicillin binding protein transpeptidase domain (IPR001460); Glycosyltransferase family 51 (IPR001264) Pfam: Transglycosylase; Penicillin binding protein transpeptidase singal peptide no TMHs HTH predicted; High confidence in function and specificity; penicillin-binding protein 1A	4010609..4012981	Azoarcus sp. BH72	4609566
YP_935154.1	CDS	cyaY	NC_008702.1	4012971	4013348	R	CyaY protein that belongs to the frataxin family.Probably involved in iron metabolism. 33% similarity to CyaY protein from E.coli. SWISSPROT:CYAY_YERPE:P46356 InterPro:IPR002908; Frataxin_like. Pfam:PF01491; Frataxin_Cyay; 1.; High confidence in function and specificity; putative CyaY protein	complement(4012971..4013348)	Azoarcus sp. BH72	4609271
YP_935155.1	CDS	azo3653	NC_008702.1	4013347	4013517	D	Conserved hypothetical secreted protein. Homology to ypo3846 of Y. pestis of 42% (trembl|Q8ZAF7). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	4013347..4013517	Azoarcus sp. BH72	4608547
YP_935156.1	CDS	lysA2	NC_008702.1	4013514	4014788	D	Diaminopimelate decarboxylase, LysA. Similar to sprot|DCDA_PSEAE (64%). Pyridoxal-dependent decarboxylases that act on ornithine-, lysine-, arginine- and related substrates can be classified into different families on the basis of sequence similarity. Prokaryotic diaminopimelic acid decarboxylase (DAPDC) catalyses the conversion of diaminopimelic acid into lysine, the final step of lysine biosynthesis. InterPro(PR01181): Diaminopimelate decarboxylase InterPro(PF00278): Orn/DAP/Arg decarboxylases family 2; High confidence in function and specificity; LysA2 protein	4013514..4014788	Azoarcus sp. BH72	4608053
YP_935157.1	CDS	azo3655	NC_008702.1	4014811	4015158	R	Conserved hypothetical protein. Homology to ebA2272 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA2272(KEGG)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(4014811..4015158)	Azoarcus sp. BH72	4609185
YP_935158.1	CDS	dacB	NC_008702.1	4015219	4016685	D	Penicillin-binding protein 4 precursor (PBP-4) [Includes: D-alanyl-D- alanine carboxypeptidase (EC 3.4.16.4) (DD-peptidase) (DD- carboxypeptidase); D-alanyl-D-alanine-endopeptidase (DD-endopeptidase)]. Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction. PBP4: D-alanyl-D-alanine carboxypeptid; High confidence in function and specificity; serine-type D-Ala-D-Ala carboxypeptidase	4015219..4016685	Azoarcus sp. BH72	4608054
YP_935159.1	CDS	azo3657	NC_008702.1	4016702	4017118	R	Conserved hypothetical membrane protein. Homology to bb4211 of B. bronchiseptica of 37% (trembl|Q7WFQ9(SRS)). No domains predicted. No signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(4016702..4017118)	Azoarcus sp. BH72	4608576
YP_935160.1	CDS	yigC	NC_008702.1	4017168	4018658	R	3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylase). CATALYZES THE DECARBOXYLATION OF 3-OCTAPRENYL-4-HYDROXY BENZOATE TO 2-OCTAPRENYLPHENOL (BY SIMILARITY).; High confidence in function and specificity; 3-polyprenyl-4-hydroxybenzoate decarboxylase	complement(4017168..4018658)	Azoarcus sp. BH72	4608055
YP_935161.1	CDS	pyrF	NC_008702.1	4018668	4019480	R	type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase	complement(4018668..4019480)	Azoarcus sp. BH72	4610185
YP_935162.1	CDS	npd2	NC_008702.1	4019543	4020316	R	Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase	complement(4019543..4020316)	Azoarcus sp. BH72	4609672
YP_935163.1	CDS	azo3661	NC_008702.1	4020405	4022477	R	Conserved hypothetical molybdopterin oxidoreductase. Homology to rsc2859 of R. solanacearum of 60% (trembl|Q8XVH2). Tigrfam: bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxidoreductases. Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain. Helixturnhelix motif. no signal sequenz. no TMHs; Conserved hypothetical protein; molybdopterin oxidoreductase	complement(4020405..4022477)	Azoarcus sp. BH72	4609409
YP_935164.1	CDS	azo3662	NC_008702.1	4022532	4023209	R	Conserved hypothetical secreted proteinn. Homology to ebA3326 Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA3326(KEGG)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(4022532..4023209)	Azoarcus sp. BH72	4608056
YP_935165.1	CDS	pyrE	NC_008702.1	4023187	4023855	R	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase	complement(4023187..4023855)	Azoarcus sp. BH72	4608057
YP_935166.1	CDS	xthA2	NC_008702.1	4023919	4024701	D	Exodeoxyribonuclease (EC 3.1.11.2). InterPro: AP endonucleases family 1; High confidence in function and specificity; exodeoxyribonuclease III	4023919..4024701	Azoarcus sp. BH72	4609671
YP_935167.1	CDS	azo3665	NC_008702.1	4024848	4027106	D	Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein; putative signaling protein	4024848..4027106	Azoarcus sp. BH72	4610131
YP_935168.1	CDS	azo3666	NC_008702.1	4027103	4028941	D	Putative sensor histidine kinase, low similarity to SWISSPROT: sprot|KINB_PSEAE (13% Pseudomonas aeruginosa,alginate biosynthesis sensor protein KinB) / TREMBL: trembl|Q50853 (13% Myxococcus xanthus, AsgA) InterPro: IPR004358 Bact_sens_pr_C. IPR003661 His_kinA_N. IPR005467 His_kinase. Pfam: PF02518 HATPase_c. PF00512 HisKA. SMART: SM00387 HATPase_c. SM00388 HisKA. TMHMM reporting 1 transmembrane helices.; Family membership; putative sensor histidine kinase	4027103..4028941	Azoarcus sp. BH72	4608058
YP_935169.1	CDS	azo3667	NC_008702.1	4029038	4029346	D	Conserved hypothetical membrane protein. Homology to RS05100 of Ralstonia solanacearum of 50% (trembl|Q8Y1D7(SRS)). Has PF05957, Bacterial protein of unknown function (DUF883);IPR010279; This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide. 1 TMH; Conserved hypothetical protein; hypothetical protein	4029038..4029346	Azoarcus sp. BH72	4608059
YP_935170.1	CDS	azo3668	NC_008702.1	4029352	4029735	D	Conserved hypothetical membrane protein. Homology to rs05101 R. solanacearum of 36% (trembl|Q8Y1D8(SRS)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein; hypothetical protein	4029352..4029735	Azoarcus sp. BH72	4608060
YP_935171.1	CDS	azo3669	NC_008702.1	4029732	4030103	D	Conserved hypothetical protein. Homology to ebD74 of Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebD74(KEGG)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	4029732..4030103	Azoarcus sp. BH72	4608061
YP_935172.1	CDS	hpt	NC_008702.1	4030246	4030803	D	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase	4030246..4030803	Azoarcus sp. BH72	4608062
YP_935173.1	CDS	azo3671	NC_008702.1	4030814	4031149	D	Conserved hypothetical protein. Homology to BPP4351 of B.parapertussis of 38% (trembl:Q7W2Q3). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	4030814..4031149	Azoarcus sp. BH72	4609027
YP_935174.1	CDS	qseB2	NC_008702.1	4031270	4031950	D	DNA-binding response regulator,; High confidence in function and specificity; DNA-binding response regulator	4031270..4031950	Azoarcus sp. BH72	4608063
YP_935175.1	CDS	qseC2	NC_008702.1	4032106	4033452	D	Two-component system histidine kinase,; High confidence in function and specificity; two-component system histidine kinase	4032106..4033452	Azoarcus sp. BH72	4609687
YP_935176.1	CDS	mucD4	NC_008702.1	4033530	4034963	D	Probable serine protease MucD. Homology to mucD of P. aeruginosa of 51% (trembl|Q57155) Pfam: Trypsin; PDZ domain (Aslo konwn as DHR or GLGF) no TMH signal peptide; High confidence in function and specificity; serine protease MucD	4033530..4034963	Azoarcus sp. BH72	4609688
YP_935177.1	CDS	azo3675	NC_008702.1	4035014	4035511	D	Hypothetical protein predicted by Glimmer/Critica. Homology to bpp3105 of B. parapertussis of 20% (trembl|Q7W622). no domains predicted. no signal peptide. no TMHs; hypothetical protein	4035014..4035511	Azoarcus sp. BH72	4609286
YP_935178.1	CDS	nagL2	NC_008702.1	4035537	4036184	R	Probable maleylpyruvate isomerase. Homology to nagL of Ralstonia spU of 50% (trembl|O86043) NagL is a reduced glutathione-dependent maleylpyruvate isomerase catalyzing the isomerization of maleypyruvate to fumarylpyruvate. InterPro: Glutathione S-transferase N terminus (IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminal domaine no signal peptide no TMHs; High confidence in function and specificity; maleylpyruvate isomerase	complement(4035537..4036184)	Azoarcus sp. BH72	4608064
YP_935179.1	CDS	dctP6	NC_008702.1	4036298	4037326	R	TRAP-dicarboxylate transporter. Binds c4-dicarboxylates; part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. 23% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide: present.; Specificity unclear; putative c4-dicarboxylate-binding periplasmic protein	complement(4036298..4037326)	Azoarcus sp. BH72	4609314
YP_935180.1	CDS	azo3678	NC_008702.1	4037367	4038380	R	This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. Similar to TREMBL:Q9KSB3 (67% identity); TREMBL:Q92LT4 (67% identity); TREMBL:Q8EGD4 (61% identity). Pfam (PF01557): Fumarylacetoacetate (FAA) hydrolase family.; Family membership; fumarylacetoacetate hydrolase family protein	complement(4037367..4038380)	Azoarcus sp. BH72	4608607
YP_935181.1	CDS	azo3679	NC_008702.1	4038439	4038972	R	Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway. Similar to trembl|Q89SS0 (63%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership; glyoxalase-family protein	complement(4038439..4038972)	Azoarcus sp. BH72	4608065
YP_935182.1	CDS	azo3680	NC_008702.1	4038995	4039219	R	Conserved hypothetical protein. Homology to RS01748 of R.solanacearum of 59% (trembl:Q8XRY0). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(4038995..4039219)	Azoarcus sp. BH72	4608066
YP_935183.1	CDS	mhpA	NC_008702.1	4039232	4040899	R	Putative oxygenase. 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-), InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Specificity unclear; FAD-dependent oxidoreductase	complement(4039232..4040899)	Azoarcus sp. BH72	4608067
YP_935184.1	CDS	azo3682	NC_008702.1	4040974	4041939	R	Beta-lactamase II precursor (EC 3.5.2.6) (Penicillinase) (Cephalosporinase). Can hydrolyze carbapenem compounds. InterPro:IPR001279-Metallo-beta-lactamase superfamily TREMBL:Q8XRX8-72% identity TREMBL:Q7VUG6- 62% Pfam:PF00753-LactamaseB, Ribosomal proteinS6e,ThiC family TIGRFAM:TIGR00010- TatD/hisF family TMHMM predicted transmembrane helix. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity; putative cyclase	complement(4040974..4041939)	Azoarcus sp. BH72	4609217
YP_935185.1	CDS	gylR	NC_008702.1	4042117	4042941	D	Putative transcriptional regulator iclR-family,; Family membership; IclR family transcriptional regulator	4042117..4042941	Azoarcus sp. BH72	4608068
YP_935186.1	CDS	azo3684	NC_008702.1	4043053	4043889	D	Putative periplasmic binding protein-related protein.This family includes several of which are involved in iron transport. 24%; Function unclear; putative periplasmic binding protein	4043053..4043889	Azoarcus sp. BH72	4608974
YP_935187.1	CDS	azo3685	NC_008702.1	4043889	4047515	D	Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices.; Family membership; putative hybrid sensor and regulator protein	4043889..4047515	Azoarcus sp. BH72	4608069
YP_935188.1	CDS	rpfG	NC_008702.1	4047603	4048715	D	Probable response regulator, HD. IPR003607; Met_phsphohydro. IPR001789; Response_reg. IPR008328; Res_reg_HDGYP. Pfam: PF01966; HD. PF00072; Response_reg. SMART: SM00471; HDc. SM00448; REC.; Specificity unclear; response regulator	4047603..4048715	Azoarcus sp. BH72	4608070
YP_935189.1	CDS	cc43	NC_008702.1	4048737	4049372	R	Putative cytochrome c4. Homology to cc4 of A. vinelandii of 29% (sprot|CYC4_AZOVI). Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems. Pfam: cytochrome C signal peptide no TMHs; putative cytochrome c4	complement(4048737..4049372)	Azoarcus sp. BH72	4609759
YP_935190.1	CDS	azo3688	NC_008702.1	4049428	4049787	R	Conserved hypothetical protein. Homology to pspto0091 of P. syringae of 35% (trembl|Q88BC6). Pfam: DUF861. This family consists of several proteins which seem to be specific to plants and bacteria. The function of this family is unknown. no signal peptide. no TMHs; hypothetical protein	complement(4049428..4049787)	Azoarcus sp. BH72	4608440
YP_935191.1	CDS	murB	NC_008702.1	4049799	4050842	R	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase	complement(4049799..4050842)	Azoarcus sp. BH72	4608071
YP_935192.1	CDS	azo3690	NC_008702.1	4050942	4051349	R	Conserved hypothetical membrane protein. Homology to atu1643 of A. tymefaciens of 39% (trembl|Q8UEW1(SRS)). Pfam: Bacterial transmembrane pair family. This domain represents a conserved pair of transmembrane helices. It appears to be found as two tandem repeats in a family of hypothetical proteins. signal peptide. 3 TMHs; Conserved hypothetical protein; hypothetical protein	complement(4050942..4051349)	Azoarcus sp. BH72	4609288
YP_935193.1	CDS	azo3691	NC_008702.1	4051624	4053654	R	Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.; Family membership; putative methyl-accepting chemotaxis transducer	complement(4051624..4053654)	Azoarcus sp. BH72	4608072
YP_935194.1	CDS	azo3692	NC_008702.1	4053784	4054350	D	Putative N-acetyltransferase,51% Identity to TrEMBl;Q7WQB1,54% Identity to TrEMBL;Q63LT2,Q7WCA7. Has PF00583, Acetyltransferase (GNAT) family;IPR000182,GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions. Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families. These include the Gcn5-related acetyltransferases (GNATs); the MYST (for `MOZ, Ybf2/Sas3,Sas2 and Tip60)-related HATs; p300/CBP HATs; the general transcription factor HATs, which include the TFIID subunit TAF250; and the nuclear hormone-related HATs SRC1 and ACTR (SRC3). The GCN5-related N-acetyltransferase superfamily includes such enzymes as the histone acetyltransferases GCN5 and Hat1, the elongator complex subunit Elp3, the mediator-complex subunit Nut1, and Hpa2; putative N-acetyltransferase	4053784..4054350	Azoarcus sp. BH72	4608073
YP_935195.1	CDS	azo3693	NC_008702.1	4054347	4055573	D	Similar to hypothetical integral membrane transport protein yidY (MFS family). Signal peptide containing non secretory protein. With 12 putative transmembrane helices. General transport of carbohydrates , amino acids, and other small molecules.; Conserved hypothetical protein; hypothetical protein	4054347..4055573	Azoarcus sp. BH72	4608074
YP_935196.1	CDS	azo3694	NC_008702.1	4055667	4055852	D	Hypothetical secreted protein. No good homology to the data bank. Has Signal Peptide.; hypothetical protein	4055667..4055852	Azoarcus sp. BH72	4608075
YP_935197.1	CDS	trpS	NC_008702.1	4056007	4057344	R	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase	complement(4056007..4057344)	Azoarcus sp. BH72	4608076
YP_935198.1	CDS	azo3696	NC_008702.1	4057400	4057786	R	Conserved hypothetical secreted protein. Homology to bb3068 of B. bronchiseptica of 31% (trembl|Q7WHY8(SRS)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(4057400..4057786)	Azoarcus sp. BH72	4610037
YP_935199.1	CDS	azo3697	NC_008702.1	4057811	4058158	R	Hypothetical secreted protein. No homology to the data bank. No domains predicted. No TMHs. Has signal peptide.; hypothetical protein	complement(4057811..4058158)	Azoarcus sp. BH72	4608077
YP_935200.1	CDS	azo3698	NC_008702.1	4058405	4058953	D	Conserved hypothetical protein. Homology to Daro03001371 of Dechloromonas aromatica of 43% (gi|53730748|ref|ZP_00348943.1|(NBCI ENTREZ)). No doamins predicted. No signal peptide. No TMHs.; hypothetical protein	4058405..4058953	Azoarcus sp. BH72	4608078
YP_935201.1	CDS	azo3699	NC_008702.1	4058961	4060172	D	Conserved hypothetical protein, 38% identity(51% similarity) to TrEMBL;Q8KAU5. TrEMBL; Q6MRD6(59% identity). Has PF07075, Protein of unknown function (DUF1343);IPR008302, UCP016719; This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.There are currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function.; Function unclear; hypothetical protein	4058961..4060172	Azoarcus sp. BH72	4608079
YP_935202.1	CDS	trxC2	NC_008702.1	4060198	4060578	R	Probable thioredoxin-disulfide reductase. Homology to trxC3 (THI3_CORNE) of C. nephridii of 43%. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Pfam: Thioredoxin no signal peptide no TMHs; Family membership; thioredoxin-disulfide reductase	complement(4060198..4060578)	Azoarcus sp. BH72	4608080
YP_935203.1	CDS	azo3701	NC_008702.1	4060726	4061031	D	Conserved hypothetical protein. Homology to bll7423 of B. japonicum of 53% (trembl|Q89DL6). Pfam: Antibiotic biosynthesis monooxygenase. no TMHs. No signal peptide.; hypothetical protein	4060726..4061031	Azoarcus sp. BH72	4610044
YP_935204.1	CDS	azo3702	NC_008702.1	4061111	4061821	D	conserved hypothetical protein. Homology to Avin02001428 of Azotobacter vinelandii of 54% (gi|53612536|ref|ZP_00091632.2|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	4061111..4061821	Azoarcus sp. BH72	4608081
YP_935205.1	CDS	azo3703	NC_008702.1	4061834	4062295	R	Conserved hypothetical membrane protein. Homology to PM2013 of P. multocida of 44% (tremble:Q9CJJ4). probable signal peptide. probable 2 TMHS; Conserved hypothetical protein; hypothetical protein	complement(4061834..4062295)	Azoarcus sp. BH72	4608082
YP_935206.1	CDS	azo3704	NC_008702.1	4062391	4063305	D	Hypothetical membrane protein. No homology of the entire protein to the data bank. Has PF05875;Alkaline phytoceramidase (aPHC):This family consists of several eukaryotic Alkaline phytoceramidase (aPHC) sequences. Ceramidases are enzymes involved in regulating cellular levels of ceramides, sphingoid bases, and their phosphates. Alkaline phytoceramidase (aPHC) is responsible for the hydrolysis of phytoceramide. No signal peptide. 6 TMHs.; hypothetical protein	4062391..4063305	Azoarcus sp. BH72	4608083
YP_935207.1	CDS	gapR	NC_008702.1	4063257	4064321	R	Putative AraC family transcriptional regulator,; High confidence in function and specificity; AraC family transcriptional regulator	complement(4063257..4064321)	Azoarcus sp. BH72	4608084
YP_935208.1	CDS	azo3706	NC_008702.1	4064470	4065540	D	Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.; hypothetical protein	4064470..4065540	Azoarcus sp. BH72	4608860
YP_935209.1	CDS	azo3707	NC_008702.1	4065556	4065882	R	Conserved hypothetical protein. Homology to sty1393 of S. typhi of 34% (trembl|Q8Z792). Pfam: Antibiotic biosynthesis monooxygenase. no signal peptide. no TMHs; hypothetical protein	complement(4065556..4065882)	Azoarcus sp. BH72	4608085
YP_935210.1	CDS	azo3708	NC_008702.1	4065983	4066393	R	Dioxygenases catalyze the incorporation of both atoms of molecular oxygen into substrates. Cleavage of aromatic rings is one of the most important function of dioxygenases. Similar to trembl|Q7WJ14 (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership; dioxygenase-family protein	complement(4065983..4066393)	Azoarcus sp. BH72	4608086
YP_935211.1	CDS	azo3709	NC_008702.1	4066490	4066942	R	Family membership; ORF8; hypothetical protein	complement(4066490..4066942)	Azoarcus sp. BH72	4608087
YP_935212.1	CDS	azo3710	NC_008702.1	4067068	4067532	R	Conserved hypothetical transferase. Homology to the IAA acetyltransferase of A. brasilense of 37% (sprot|IAAT_AZOBR). The IAA acetyltransferase participates in the tryptophan-dependent indole-3-acetic acid production, which is a phytohormone released by A.brasilense. Interpro: GCN5-related N-acetyltransferase (IPR000182). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Conserved hypothetical protein; acetyltransferase	complement(4067068..4067532)	Azoarcus sp. BH72	4608088
YP_935213.1	CDS	azo3711	NC_008702.1	4067656	4068402	R	Similar to SWISSPROT:P39367 (68% identity),TREMBL:Q8Z1C8 (66% identity).; hypothetical protein	complement(4067656..4068402)	Azoarcus sp. BH72	4608089
YP_935214.1	CDS	azo3712	NC_008702.1	4068452	4068979	R	conserved hypothetical protein. Homology to Raeut03002407 of Ralstonia eutropha of 48% (gi|46132577|ref|ZP_00171131.2|(NBCI ENTREZ)). Pfam: NUDIX domain. No signal peptide. No TMHs.; hypothetical protein	complement(4068452..4068979)	Azoarcus sp. BH72	4608090
YP_935215.1	CDS	bleO	NC_008702.1	4069022	4069390	R	Bleomycin (Blm) is a glycopeptide antibiotic produced naturally by actinomycetes. It is a strong DNA-cutting agent and thus finds use as a potent anti-cancer drug. Actinomycetes have developed a defence mechanism against this lethal compound, producing a protein that confers resistance to Blm through drug sequestering.Putative Bleomycin resistance protein,; Family membership; putative bleomycin resistance protein	complement(4069022..4069390)	Azoarcus sp. BH72	4608091
YP_935216.1	CDS	azo3714	NC_008702.1	4069873	4070424	R	Probable Acetyltransferase. Has weak homology with hits in the database, TrEMBL;Q7N1H0(56% Identity). Has PF00583, Acetyltransferase (GNAT) family; IPR000182, GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions.;Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated. The histone acetyltransferases are divided into five families. These include the Gcn5-related acetyltransferases (GNATs); the MYST (for `MOZ, Ybf2/Sas3,Sas2 and Tip60)-related HATs; p300/CBP HATs; the general transcription factor HATs, which include the TFIID subunit TAF250; and the nuclear hormone-related HATs SRC1 and ACTR (SRC3). The GCN5-related N-acetyltransferase superfamily includes such enzymes as the histone acetyltransferases GCN5 and Hat1, the elongator complex subunit Elp3, the mediator-complex subunit Nut1, and Hpa2; Family membership; acetyltransferase	complement(4069873..4070424)	Azoarcus sp. BH72	4608399
YP_935217.1	CDS	azo3715	NC_008702.1	4070525	4070932	R	Hypothetical membrane protein. Homology to an orf of E. coli of 29% (trembl|Q8VNQ4). no domains predricted. no signal peptide. 3 TMHs; hypothetical protein	complement(4070525..4070932)	Azoarcus sp. BH72	4608092
YP_935218.1	CDS	azo3716	NC_008702.1	4071043	4071537	R	hypothetical protein	complement(4071043..4071537)	Azoarcus sp. BH72	4608093
YP_935219.1	CDS	azo3717	NC_008702.1	4071620	4071769	R	Region start changed from 4071796 to 4071769 (-27 bases), , Changed start from att to next atg; hypothetical protein	complement(4071620..4071769)	Azoarcus sp. BH72	4608094
YP_935220.1	CDS	azo3718	NC_008702.1	4071881	4072303	R	hypothetical protein	complement(4071881..4072303)	Azoarcus sp. BH72	4608095
YP_935221.1	CDS	azo3719	NC_008702.1	4072411	4072626	R	hypothetical protein	complement(4072411..4072626)	Azoarcus sp. BH72	4608096
YP_935222.1	CDS	azo3720	NC_008702.1	4072842	4073585	D	Putative truncated transposase for insertion sequence element IS1328. Required for the transposition of the insertion element (Potential). Homology only to the N-terminus.; Family membership; transposase	4072842..4073585	Azoarcus sp. BH72	4608097
YP_935223.1	CDS	azo3721	NC_008702.1	4073607	4073966	D	Putative truncated transposase for insertion sequence element IS1328. Required for the transposition of the insertion element (Potential). InterPro: Transposase IS116/IS110/IS902 family. Homoloy only to the C-terminus.; Specificity unclear; transposase	4073607..4073966	Azoarcus sp. BH72	4608098
YP_935224.1	CDS	azo3722	NC_008702.1	4076853	4077803	R	Hypothetical protein, Has very weak or no homologs in the Database. Has No domains, repeats, motifs or features predicted above threshold score.; hypothetical protein	complement(4076853..4077803)	Azoarcus sp. BH72	4608099
YP_935225.1	CDS	azo3723	NC_008702.1	4077851	4078369	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(4077851..4078369)	Azoarcus sp. BH72	4608100
YP_935226.1	CDS	azo3724	NC_008702.1	4078566	4079330	D	Truncated integrase/recombinase, probably Integrase/recombinase. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus; truncated integrase/recombinase	4078566..4079330	Azoarcus sp. BH72	4608101
YP_935227.1	CDS	azo3725	NC_008702.1	4079327	4079527	D	Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus.; Family membership; integrase	4079327..4079527	Azoarcus sp. BH72	4608102
YP_935228.1	CDS	metH	NC_008702.1	4079534	4083235	R	one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase	complement(4079534..4083235)	Azoarcus sp. BH72	4608103
YP_935229.1	CDS	azo3727	NC_008702.1	4083455	4084066	R	Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present.; Conserved hypothetical protein; hypothetical protein	complement(4083455..4084066)	Azoarcus sp. BH72	4609209
YP_935230.1	CDS	azo3728	NC_008702.1	4084068	4084556	R	Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present.; Family membership; lipoprotein	complement(4084068..4084556)	Azoarcus sp. BH72	4608104
YP_935231.1	CDS	livK3	NC_008702.1	4084668	4085792	D	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_ECOLI (31%) and to trembl|Q7NV64 (54%). Pfam (PF01094): Receptor family ligand binding region Pfam (PF00861): Ribosomal L18p/L5e family SignalP reporting Signal peptide.; Specificity unclear; leucine-specific binding protein	4084668..4085792	Azoarcus sp. BH72	4608105
YP_935232.1	CDS	livK4	NC_008702.1	4086174	4087289	D	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to trembl|Q7NV64 (58%) and to sprot|LIVK_ECOLI (33%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; leucine-specific binding protein	4086174..4087289	Azoarcus sp. BH72	4609155
YP_935233.1	CDS	livH	NC_008702.1	4087402	4088334	D	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar trembl|Q7NXX3 (60%), to sprot|BRAD_PSEAE (47%) and to sprot|LIVH_ECOLI (44%). Pfam (PF02653): Branched-chain amino acid transport system / permease component TMHMM reporting seven Tmhelix. gntP: gluconate transporter; Specificity unclear; ABC transporter permease	4087402..4088334	Azoarcus sp. BH72	4609156
YP_935234.1	CDS	livM5	NC_008702.1	4088347	4089444	D	Putative branched-chain amino acid transport permease. Homology to livM of S. typhimurium of 44%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. no signal peptide probable 8 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	4088347..4089444	Azoarcus sp. BH72	4609151
YP_935235.1	CDS	livG2	NC_008702.1	4089441	4090214	D	Probable high-affinity branched-chain amino acid transport ATP-binding protein BraF. ATP-binding cassette (ABC) transporters are multidomain membrane proteins,responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. BraF is a COMPONENT OF THE HIGH AFFINITY LEUCINE ISOLEUCINE VALINE TRANSPORT SYSTEM (LIV-I) WHICH IS OPERATIVE WITHOUT NA(+) AND IS SPECIFIC FOR ALANINE AND THREONINE IN ADDITION TO BRANCHED-CHAIN AMINO ACIDS. Similar to trembl|Q7NXX1 (67%), to sprot|BRAF_PSEAE (45%) and to sprot|LIVG_ECOLI (44%). Pfam (PF00005): ABC transporter Smart (SM00382): AAA ATPase superfamily ProSite (PS50101): ATP/GTP-binding site motif A (P-loop); Specificity unclear; ABC transporter ATP-binding protein	4089441..4090214	Azoarcus sp. BH72	4609162
YP_935236.1	CDS	azo3734	NC_008702.1	4090204	4090938	D	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q7NXX0 (58%) and to trembl|Q7VVD3 (59%). Smart: AAA ATPases; Specificity unclear; ABC transporter ATP-binding protein	4090204..4090938	Azoarcus sp. BH72	4609150
YP_935237.1	CDS	bcr2	NC_008702.1	4090917	4092113	R	Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General carbohydrate, amino acid , and divalent cation transport. Occurence of signal peptide and 12 transmembrane helices. Presence of DUF domains and Cation transport ATPase C-terminus domains. 35% identity and 47% similarity to bcr from X.axonopodis. Probably it is a copy of bcr1 in Azoarcus BH72 genome.; Conserved hypothetical protein; putative bicyclomycin resistance protein	complement(4090917..4092113)	Azoarcus sp. BH72	4608106
YP_935238.1	CDS	azo3736	NC_008702.1	4092166	4093665	R	Conserved hypothetical protein. Homology to rsc0338 of R. solanacearum of 64% (trembl|Q8Y2J7). Probable Mg(2+) chelatase family protein. InterPro: Mg chelatase-related protein (IPR004482); MCM family (IPR001208); AAA ATPase superfamily (IPR003593); Magnesium chalatase, chlI subunit (IPR000523); TypeI antifreeze protein (IPR000104). no signal peptide. no TMHs. TIGR00368: Mg chelatase-related protein; Family membership; hypothetical protein	complement(4092166..4093665)	Azoarcus sp. BH72	4608383
YP_935239.1	CDS	azo3737	NC_008702.1	4093748	4093999	R	Conserved hypothetical protein. Homology to NE0192 of N.europaea of 52% (trembl:Q82XR2). Has PF04380, Protein of unknown function (DUF526);IPR007475 ;This is a family of uncharacterised proteins. No signal peptide. No TMHs.; putative secreted protein	complement(4093748..4093999)	Azoarcus sp. BH72	4608107
YP_935240.1	CDS	azo3738	NC_008702.1	4094284	4095024	D	Conserved hypothetical secreted protein. Homology to rsc0341 of R. solanacearum of 40% (trembl|Q8Y2J4(SRS)). no domains predicted. signal peptide. no TMHs; hypothetical protein	4094284..4095024	Azoarcus sp. BH72	4608108
YP_935241.1	CDS	glnK	NC_008702.1	4095083	4095421	D	PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ3 (100%) and to trembl|Q7NQY3 (87%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity; PII-like signal transmitter protein GlnK	4095083..4095421	Azoarcus sp. BH72	4608109
YP_935242.1	CDS	amtB	NC_008702.1	4095436	4096842	D	Ammonium transporter 1 member 1 (AtAMT1;1). Involved in high affinity ammonium uptake. TREMBL:Q8RP89: 100% identity (published) InterPro:IPR001905; Ammonium_transpt. IPR002229; RhesusRHD. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp PRINTS PR00342; RHESUSRHD. TIGRFAMs TIGR00836; amt; PROSITE: PS01219; AMMONIUM_TRANSP SignalP predicted signal peptide present (0.997 probability). TMHMM predicted 12 transmembrane helices; High confidence in function and specificity; ammonium transporter	4095436..4096842	Azoarcus sp. BH72	4608899
YP_935243.1	CDS	ompW	NC_008702.1	4097017	4097757	D	Outer membrane protein W precursor. Acts as a receptor for colicin S4.; High confidence in function and specificity; outer membrane protein	4097017..4097757	Azoarcus sp. BH72	4608316
YP_935244.1	CDS	purU	NC_008702.1	4097840	4098715	R	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase	complement(4097840..4098715)	Azoarcus sp. BH72	4609449
YP_935245.1	CDS	thrH	NC_008702.1	4098817	4099428	R	catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity; phosphoserine phosphatase	complement(4098817..4099428)	Azoarcus sp. BH72	4609665
YP_935246.1	CDS	azo3744	NC_008702.1	4099596	4100801	D	HD-domain containing protein,; Conserved hypothetical protein; HD-domain-containing protein	4099596..4100801	Azoarcus sp. BH72	4609945
YP_935247.1	CDS	yheS	NC_008702.1	4100816	4102747	R	ABC transporter ATP-binding protein yheS. Nonsecretory protein with Signal peptide. Presence of oxidoreductase Molybdopterin binding domain, M-protein repeats, RecF protein domains, Cu amine oxidase N3 domain,K+ channels and iron-sulphur binding potentials.57% identity and 68% similarity to Dechloromonas ATPase component of ABC transporter ureG: urease accessory protein UreG; Family membership; ABC transporter ATP-binding protein	complement(4100816..4102747)	Azoarcus sp. BH72	4608110
YP_935248.1	CDS	azo3746	NC_008702.1	4102815	4103438	D	Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide no TMHs; hypothetical protein	4102815..4103438	Azoarcus sp. BH72	4610182
YP_935249.1	CDS	azo3747	NC_008702.1	4103463	4104068	R	Catalyzes the isomerization of 2-hydroxychromene-2-carboxylate (hcca) to trans-o-hydroxybenzylidenepyruvate (thbpa). Upper napthalene catabolic pathway which involves conversion of napthalene to salicylate. Similar to TREMBL:Q7WEK4 (57% identity); TREMBL:Q9I714 (35% identity); SWISSPROT:Q51948 (29% identity). InterPro: 2-hydroxychromene-2-carboxylate isomerase Pfam (HCCA_isomerase): 2-hydroxychromene-2-carboxylate isomerase.; Specificity unclear; 2-hydroxychromene-2-carboxylate isomerase	complement(4103463..4104068)	Azoarcus sp. BH72	4608111
YP_935250.1	CDS	azo3748	NC_008702.1	4104098	4104472	R	Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(4104098..4104472)	Azoarcus sp. BH72	4608112
YP_935251.1	CDS	ampR	NC_008702.1	4104611	4105519	D	Probable HTH-type transcriptional activator ampR. Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (ampC) in the presence of beta-lactams and induces it in the absence of them. Similar to SWISSPROT: sprot|AMPR_PSEAE (34% Pseudomonas aeruginosa,HTH-type transcriptional activator AmpR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; LysR family transcriptional regulator	4104611..4105519	Azoarcus sp. BH72	4608113
YP_935252.1	CDS	azo3750	NC_008702.1	4105616	4106194	D	This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoatesynthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate. Similar to TREMBL:Q7NWS7 (61% identity); TREMBL:Q8UIM8 (57% identity); TREMBL:Q89UX3 (33% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Family membership; isochorismatase family protein	4105616..4106194	Azoarcus sp. BH72	4608315
YP_935253.1	CDS	darR	NC_008702.1	4106205	4107167	D	Probable AraC family transcriptional regulator,; High confidence in function and specificity; AraC family transcriptional regulator	4106205..4107167	Azoarcus sp. BH72	4608114
YP_935254.1	CDS	azo3752	NC_008702.1	4107175	4108071	R	Conserved hypothetical membrane protein. Homology to RSC0519 of R. solanacearum of 51%. InterPro: Integral membrane protein DUF6. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter. Pfam: Integral membrane protein DUF6. probable signal peptide. probable 9 TMHs; Conserved hypothetical protein; hypothetical protein	complement(4107175..4108071)	Azoarcus sp. BH72	4608588
YP_935255.1	CDS	putA	NC_008702.1	4108137	4111802	R	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase	complement(4108137..4111802)	Azoarcus sp. BH72	4608115
YP_935256.1	CDS	azo3754	NC_008702.1	4111993	4113042	R	Putative thiamine biosynthesis lipoprotein ApbE. Homology to apbE of Salmonella typhimurium of 27% (gi|5915687|sp|P41780|APBE_SALTY(NBCI ENTREZ)). Pfam: ApbE family. This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. More specifically is may be involved in the conversion of aminoimidazole ribotide (AIR) to 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP). No TMHs. Signal peptide present.; Family membership; putative thiamine biosynthesis lipoprotein ApbE	complement(4111993..4113042)	Azoarcus sp. BH72	4609666
YP_935257.1	CDS	gshB	NC_008702.1	4113039	4113995	R	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase	complement(4113039..4113995)	Azoarcus sp. BH72	4608116
YP_935258.1	CDS	gshA	NC_008702.1	4114008	4115303	R	glutamate--cysteine ligase. Glutathione metabolism.; High confidence in function and specificity; GshA protein	complement(4114008..4115303)	Azoarcus sp. BH72	4608945
YP_935259.1	CDS	azo3757	NC_008702.1	4115424	4116680	R	Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership; modification methyltransferase	complement(4115424..4116680)	Azoarcus sp. BH72	4608944
YP_935260.1	CDS	dcrH3	NC_008702.1	4116808	4117332	D	DcrH:hemerythrin protein, is transmembrane methyl-accepting protein probably involved in bacterial chemotaxis . 32% Hemerythrin. Pfam:PF01814; Hemerythrin; 1.; High confidence in function and specificity; hypothetical protein	4116808..4117332	Azoarcus sp. BH72	4608117
YP_935261.1	CDS	azo3759	NC_008702.1	4117384	4117836	R	Hemerythrin family protein, 38% Identity to TrEMBl:Q74G47,35% to TrEMBL; Q73NY7. Has PF01814,Hemerythrin HHE cation binding domain; IPR002063 Hemerythrin; Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor P80255 binds Cadmium so as to protect the organism from toxicity ([3]). However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial Q7WX96 is a regulator of response to NO, which suggests yet another set-up for its metal ligands . In Staphylococcus aureus P72360 has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.; hemerythrin family protein	complement(4117384..4117836)	Azoarcus sp. BH72	4608592
YP_935262.1	CDS	azo3760	NC_008702.1	4118075	4119517	D	Hypothetical secreted protein. No good homology of the entire protein to the data bank. Has PF06097,Bacterial protein of unknown function (DUF945);IPR010352; This family consists of several hypothetical bacterial proteins of unknown function. No TMHs Siganl peptide present.; hypothetical protein	4118075..4119517	Azoarcus sp. BH72	4608118
YP_935263.1	CDS	azo3761	NC_008702.1	4119639	4120235	D	Conserved hypothetical protein. Homology to ebD78 of Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebD78(KEGG)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	4119639..4120235	Azoarcus sp. BH72	4608119
YP_935264.1	CDS	azo3762	NC_008702.1	4120286	4121464	D	Hypothetical patatin-like protein. Homology to all2302 of Anabaena sp. of 20% (trembl|Q8YUN7). Pfam: Patatin. PATATIN MAY HAVE A DUAL ROLE AS A SOMATIC STORAGE PROTEIN AND AS AN ENZYME INVOLVED IN HOST RESISTANCE. THIS TUBER PROTEIN REPRESENTS APPROXIMATELY 40% OF THE TOTAL PROTEIN IN MATURE TUBERS. InterPro: Patatin (IPR002641). no signal peptide. no TMHs; patatin-like protein	4120286..4121464	Azoarcus sp. BH72	4608120
YP_935265.1	CDS	azo3763	NC_008702.1	4121479	4122924	D	Hypothetical protein. no homology to the data bank no domains no signal peptide no TMHs; hypothetical protein	4121479..4122924	Azoarcus sp. BH72	4608121
YP_935266.1	CDS	azo3764	NC_008702.1	4122934	4123830	R	Hypothetical 21.1 kDa protein in fasciation locus (ORF6). TREMBL:Q8FV26: 50% identity, 65% similarity InterPro:IPR005269; Cons_hypoth730. Pfam:PF03641; Lysine_decarbox L18_bact: ribosomal protein L18 Absence of signal peptide (Signal P predicted) Absence of transmembrane helices (TMHMM predicted); Specificity unclear; hypothetical protein	complement(4122934..4123830)	Azoarcus sp. BH72	4608122
YP_935267.1	CDS	ribA	NC_008702.1	4124278	4125519	D	Probable GTP cyclohydrolase II. TIGRFAM: ribA: GTP cyclohydrolase II; Function unclear; hypothetical protein	4124278..4125519	Azoarcus sp. BH72	4608123
YP_935268.1	CDS	azo3766	NC_008702.1	4125568	4126857	D	Conserved hypothetical protein. Homology to blr7238 of B.japonicum of 48% (trembl:Q89E49). No domains predicted. No TMHs. Signal peptide with a probability of 0.570.; hypothetical protein	4125568..4126857	Azoarcus sp. BH72	4609720
YP_935269.1	CDS	upp	NC_008702.1	4126875	4127507	D	Uracil phosphoribosyltransferase. (UMP pyrophosphorylase) (UMP diphosphorylase); High confidence in function and specificity; uracil phosphoribosyltransferase	4126875..4127507	Azoarcus sp. BH72	4608124
YP_935270.1	CDS	azo3768	NC_008702.1	4127515	4129629	R	Region start changed from 4129741 to 4129603 (-138 bases); putative catalase	complement(4127515..4129629)	Azoarcus sp. BH72	4610068
YP_935271.1	CDS	codA	NC_008702.1	4129784	4131070	D	Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase	4129784..4131070	Azoarcus sp. BH72	4608125
YP_935272.1	CDS	azo3770	NC_008702.1	4131244	4131738	D	conserved hypothetical protein, 43% identity (60% similarity) to TrEMBL; Q8ZML9. TrEMBL;Q8X937(44% identity to Escherichia coli) Has PF04972, Putative phospholipid-binding domain;IPR007055, TAD; This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. Has SMART;SM00257,LysM, Lysin motif:IPR002482; This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; LysM domain/BON superfamily protein	4131244..4131738	Azoarcus sp. BH72	4608507
YP_935273.1	CDS	fcbC2	NC_008702.1	4131848	4132270	D	Probable Hypothetical protein AQ_1494. TREMBL:Q7NVG8: 46% identity, 64% similarity. InterPro:IPR006684; 4HBcoA_thiostrse. IPR006683; Thioestr_supf. Pfam PF03061; 4HBT TIGRFAMs; TIGR00051; 4HBcoA_thiostrse TIGR00051: conserved hypothetical protein No signal peptide. No transmembrane helices.; Function unclear; thioesterase	4131848..4132270	Azoarcus sp. BH72	4608126
YP_935274.1	CDS	azo3772	NC_008702.1	4132342	4133625	D	Hypothetical protein yhiN. TREMBL:Q7NU52: 55% identity, 66% similarity InterPro; IPR001327; FAD_pyr_redox. InterPro; IPR004792; HI0933_like. InterPro; IPR000719; Prot_kinase. InterPro; IPR001100; Pyr_redox InterPro: HI0933-like protein TIGR00275: conserved hypothetical pro Pfam PF03486; HI0933_like Non-secretory protein with no signal peptide (SignalP predicted) No transmembrane helices (TMHMM predicted); Function unclear; hypothetical protein	4132342..4133625	Azoarcus sp. BH72	4608736
YP_935275.1	CDS	azo3773	NC_008702.1	4133633	4134811	R	Conserved hypothetical secreted protein. Homology to Daro03002424 of Dechloromonas aromatica of 32% (gi|41723837|ref|ZP_00150727.1|(NBCI ENTREZ)). Pfam: OmpA family. singal peptide. no TMHs; hypothetical protein	complement(4133633..4134811)	Azoarcus sp. BH72	4608127
YP_935276.1	CDS	azo3774	NC_008702.1	4134801	4136297	R	Putative serine/threonine-protein kinase (EC 2.7.11.1). Pfam: Protein kinase domain; Family membership; putative serine/threonine protein kinase	complement(4134801..4136297)	Azoarcus sp. BH72	4608128
YP_935277.1	CDS	azo3775	NC_008702.1	4136601	4137917	D	Collagenase and related proteases. Homology to ne1979 of N. europaea of 63% (trembl|Q82TC1). InterPro: Peptidase family U32 (IPR001539). Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership; ORF9; hypothetical protein	4136601..4137917	Azoarcus sp. BH72	4608129
YP_935278.1	CDS	azo3776	NC_008702.1	4137914	4138504	R	Conserved hypothetical membrane protein. Homology to ebA2790 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA2790(KEGG)). No domains predicted. no signal peptide. 2 TMHS; Conserved hypothetical protein; hypothetical protein	complement(4137914..4138504)	Azoarcus sp. BH72	4608130
YP_935279.1	CDS	azo3777	NC_008702.1	4138598	4140025	D	GGDEF family protein,; Conserved hypothetical protein; diguanylate cyclase	4138598..4140025	Azoarcus sp. BH72	4608131
YP_935280.1	CDS	staT	NC_008702.1	4140029	4140520	D	Putative streptothricin acetyltransferase. Homology to staT of S. lavenduale (sprot|STA_STRLA). Pfam: Acetyltransferase (GNAT) family. no signal peptide no TMHs; Family membership; putative streptothricin acetyltransferase	4140029..4140520	Azoarcus sp. BH72	4608132
YP_935281.1	CDS	ybiT	NC_008702.1	4140608	4142233	D	Hypothetical ABC transporter ATP-binding protein ybiT. Probably involved in the transport of Cobalt,branched chain amino acids , or multi drug resistance. Occurence of tub domains, uridine kinase domain, DUF and RecF protein like domains. Signal P present. Central region; Family membership; ABC transporter ATP-binding protein	4140608..4142233	Azoarcus sp. BH72	4609901
YP_935282.1	CDS	ptsL	NC_008702.1	4142403	4142786	D	This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The IICD domains contain the sugar binding site and the transmembrane channel; the IIA domain contains the primary phosphorylation site (the donor is phospho-HPr); IIA transfers its phosphoryl group to the IIB domain which finally transfers it to the sugar. 32% EIIA-man.IPR004720; PTSIIB_sorb. Pfam:PF03610; EIIA-man; 1.PF03830; PTSIIB_sorb; 1.; Specificity unclear; putative IIA component of sugar transport PTS system	4142403..4142786	Azoarcus sp. BH72	4610149
YP_935283.1	CDS	ptsH	NC_008702.1	4142798	4143067	D	Phosphocarrier protein HPr (Histidine-containing protein) (Protein H). This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). HPr is common to all PTS (By similarity). 64% HPr_HisP_S.IPR000032; HPr_protein.IPR002114; HPr_SerP_S. IPR005698; PTS_HPr. Pfam:PF00381; PTS-HPr; 1.; High confidence in function and specificity; putative phosphocarrier protein HPr	4142798..4143067	Azoarcus sp. BH72	4609650
YP_935284.1	CDS	ptsI	NC_008702.1	4143071	4144801	D	Phosphoenolpyruvate-protein phosphotransferase(Phosphotransferase system enzyme I)(Protein I).This is a component of the phosphoenolpyruvate dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Enzyme I is common to all PTS. 54% PEP-utilisers_N.IPR008279; PEP_mobile.IPR006318; PEP_P_trans.IPR000121; PEP_utilizers. Pfam:PF05524; PEP-utilisers_N; 1.PF00391; PEP-utilizers; 1.PF02896; PEP-utilizers_C; 1. TIGRFAMs:TIGR01417; PTS_I_fam; 1.; High confidence in function and specificity; putative phosphoenolpyruvate-protein phosphotransferase	4143071..4144801	Azoarcus sp. BH72	4609648
YP_935285.1	CDS	azo3783	NC_008702.1	4145096	4146052	D	Conserved hypothetical secreted protein. Homology to Daro03001609 of Dechloromonas aromatica of 35% (gi|53730883|ref|ZP_00151781.2|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH reported Present.; Conserved hypothetical protein; hypothetical protein	4145096..4146052	Azoarcus sp. BH72	4609996
YP_935286.1	CDS	azo3784	NC_008702.1	4146076	4146408	R	Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. TMH in signal peptide; hypothetical protein	complement(4146076..4146408)	Azoarcus sp. BH72	4608133
YP_935287.1	CDS	azo3785	NC_008702.1	4146462	4146809	R	hypothetical protein	complement(4146462..4146809)	Azoarcus sp. BH72	4608134
YP_935288.1	CDS	hupS	NC_008702.1	4146921	4148009	D	Ferredoxin hydrogenase, small subunit. Homology to hoxK of A. eutrophus of 83% (sprot:MBHS_ALCEU). This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. Tigrfam: hydA: hydrogenase (NiFe) small subunit Pfam: NADH ubiquinone oxidoreductase 20kD signal peptide no TMHs; High confidence in function and specificity; ferredoxin hydrogenase small subunit	4146921..4148009	Azoarcus sp. BH72	4608135
YP_935289.1	CDS	hupL	NC_008702.1	4148006	4149802	D	Probable ferredoxin hydrogenase, large subunit. Homology to hoxG of A. eutrophus of 68% (>sprot|MBHL_ALCEU). This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. Pfam: Nickel dpendent hydrogenase no signal peptide no TMHs; High confidence in function and specificity; ferredoxin hydrogenase large subunit	4148006..4149802	Azoarcus sp. BH72	4609053
YP_935290.1	CDS	hupC	NC_008702.1	4149947	4150654	D	Probable Ni/Fe-hydrogenase, B-type cytochrome subunit. Homology to hupZ of A. chroococcum of 65% (sprot|CYBH_AZOCH) Probable b-type cytochrome. InterPro: Nickel-dependent hydrogenase b-type cytochrome subunit (IPR000516) Pfam: Nickel-dependent hydrogenase b-type cytrochrome subunit no signal peptide 4 TMHs; High confidence in function and specificity; Ni/Fe-hydrogenase, B-type cytochrome subunit	4149947..4150654	Azoarcus sp. BH72	4609051
YP_935291.1	CDS	azo3789	NC_008702.1	4150663	4151007	D	Conserved hypothetical protein. Homology to ne1110 of N. europaea of 35% (trembl|Q82VH8). InterPro: Helix-turn-helix motif (IPR0001387). Pfam: Helix-turn-helix. no signal peptide. no TMHs; hypothetical protein	4150663..4151007	Azoarcus sp. BH72	4609043
YP_935292.1	CDS	azo3790	NC_008702.1	4151089	4151679	D	Conserved hypothetical glutathione peroxidase. Homology to gpwA of P. wisconsinensis of 52% (SWISSPROT:GPWA_PSEWI). Glutathione peroxidase (GSHPx), an enzyme whose principal function is to protect against damage from endogenously-formed hydroxyperoxides,catalyses the reduction of hydroxyperoxides by glutathione. InterPro: Glutathione peroxidase (IPR000889),Type I antifreeze protein (IPR000104). Pfam: Glutathione peroxidase. signal peptide. no TMHs; Family membership; glutathione peroxidase	4151089..4151679	Azoarcus sp. BH72	4608136
YP_935293.1	CDS	azo3791	NC_008702.1	4151699	4153393	R	Conserved hypothetical ATPase. Homology to MCA0262 of Methylococcus capsulatus of 68% (gi|53756248|gb|AAU90539.1|(NBCI ENTREZ)). InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959);AAA ATPase superfamily (IPR003593) Pfam: ATPase family associated with various cellular activities (domaine from 365 aa to 540 aa) no signal peptide. no TMHs.; Function unclear; ATPase	complement(4151699..4153393)	Azoarcus sp. BH72	4608137
YP_935294.1	CDS	hupD	NC_008702.1	4153728	4154408	D	Hydrogenase expression/formation protein hupD, 54% identity,(63% simialrity) to SwissProt:Q03004. Aliases: hoxM(SwissProt:P40591), hyaD(E.coli). Has PF01750:Hydrogenase maturation protease;The family consists of hydrogenase maturation proteases. In E. coli HypI the hydrogenase maturation protease is involved in processing of HypE the large subunit of hydrogenases 3, by cleavage of its C-terminal. IPR000671:Peptidase_M52; TIGR00072; hydrog_prot; Signal P reporting SIgnal peptide Present. No TMH present.; High confidence in function and specificity; hydrogenase expression/formation protein hupD	4153728..4154408	Azoarcus sp. BH72	4608138
YP_935295.1	CDS	hupF	NC_008702.1	4154410	4154721	D	Putative Hydrogenase expression/formation protein hupF,43% similarity to TrEMBL; Q6PTB2. No Signal Peptide or TMH reported present. Has PF01455:HupF/HypC family(IPR001109);The large subunit of [NiFe]-hydrogenase,as well as other nickel metalloenzymes, is synthesized as a precursor devoid of the metalloenzyme active site. This precursor then undergoes a complex post-translational maturation process that requires a number of accessory proteins. The hydrogenase expression/formation proteins (HUPF/HYPC) form a family of small proteins that are hydrogenase precursor-specific chaperones required for this maturation process . They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation.; High confidence in function and specificity; putative hydrogenase expression/formation protein hupF	4154410..4154721	Azoarcus sp. BH72	4609044
YP_935296.1	CDS	hupG	NC_008702.1	4154718	4155176	D	Hydrogenase-1 operon protein HyaE, 50% similarity to TrEMBL;Q8XGC7, 46% similarity to SwissProt;P19931. Alias: hupG Has PF07449:Hydrogenase-1 expression protein HyaE(IPR010893);This family contains bacterial hydrogenase-1 expression proteins approximately 120 residues long. This includes the E. coli protein HyaE, and the homologous proteins HoxO of R. eutropha and HupG of R. leguminosarum. Deletion of the hoxO gene in R. eutropha led to complete loss of the uptake [NiFe] hydrogenase activity, suggesting that it has a critical role in hydrogenase assembly. No signal peptide or TMH reported present.; High confidence in function and specificity; hydrogenase-1 operon protein hyaE	4154718..4155176	Azoarcus sp. BH72	4609045
YP_935297.1	CDS	hupH	NC_008702.1	4155192	4156064	D	Hydrogenase expression/formation protein hupH, 58% similarity to SwissProt:Q03007. TrEMBL;Q6PTB0,TrEMBL;P95499, SwissProt;P19932. Has PF04809(IPR006894):HupH hydrogenase expression protein, C-terminal conserved region;This family represents a C-terminal conserved region found in these bacterial proteins necessary for hydrogenase synthesis. Their precise function is unknown. No Signal peptide or TMH reported Present.; High confidence in function and specificity; hydrogenase-1 operon protein hupH	4155192..4156064	Azoarcus sp. BH72	4609046
YP_935298.1	CDS	hupI	NC_008702.1	4156109	4156321	D	Probable rubredoxin protein, 61% Identity to SProt;P30778, P31912. Has PF00301, Rubredoxin;Rubredoxin is a low molecular weight iron-containing bacterial protein involved in electron transfer,sometimes replacing ferredoxin as an electron carrier. No signal peptide. No TMHs.; High confidence in function and specificity; rubredoxin protein	4156109..4156321	Azoarcus sp. BH72	4609047
YP_935299.1	CDS	hupJ	NC_008702.1	4156321	4156887	D	Probable Hydrogenase expression/formation protein hupJ, 52% similarity to SwissProtP28152. Alias:hybE No Signal Peptide or TMH reported present. thiM: hydroxyethylthiazole kinase; hydrogenase expression/formation protein	4156321..4156887	Azoarcus sp. BH72	4609048
YP_935300.1	CDS	hupK	NC_008702.1	4156888	4157994	D	Putative hydrogenase expression/formation protein HupK. Homology to hupK of R. leguminosarum of 33% (gi|48731|emb|CAA37158.1|(NCBI ENTREZ). No domains predicted. No signal peptide or TMH present., ,; Family membership; putative hydrogenase expression/formation protein HupK	4156888..4157994	Azoarcus sp. BH72	4609049
YP_935301.1	CDS	hypA	NC_008702.1	4157987	4158331	D	Hydrogenase nickel incorporation protein hypA. Homology to hypA2 of A. eutrophus of 50% (AAB60888). Probably plays a role in an hydrogenase nickel cofactor insertion step. Pfam: Hydrogenase eypression/synthesis hypA Tigrfam: hypA: hydrogenase expression/formation protein no TMHs; High confidence in function and specificity; hydrogenase nickel inorporation protein hypA	4157987..4158331	Azoarcus sp. BH72	4609050
YP_935302.1	CDS	hypB	NC_008702.1	4158470	4159393	D	Probable hydrogenase accessory protein HypB. Homology to hypB of E. coli of 56% (sprot|HYPB_ECOLI). IS REQUIRED FOR THE FORMATION OF HYDROGENASE ISOENZYMES. AFFECTS SOME ASPECT OF THE PROCESSING OF HYDROGENASES and NICKEL INCORPORATION scince HYPB GENE LESIONS CAN BE COMPLEMENTED BY HIGH NICKEL ION CONCENTRATION IN THE MEDIUM. Pfam: HypB/UreG nucleotide-binding domain Tigrfam: hypB: hydrogenase accessory protein Hyp no signal peptide no TMHs; High confidence in function and specificity; hydrogenase nickel incorporation protein HypB	4158470..4159393	Azoarcus sp. BH72	4609058
YP_935303.1	CDS	hypF	NC_008702.1	4159390	4161762	D	probable hydrogenase maturation protein HypF. Homology to hypF2 of A. eutrophus of 58% (sprot|HYF2_ALCEU). Involved in the hydrogenase maturation process. InterPro: Hydrogenase maturation protein HypF (IPR00421), SuA5/yciO/yrdC family (IPR004388); Acylphosphatase (IPR001792) Pfam: Acylphosphatase, yrdC domain Tigrfam: hypF: hydrogenase maturation protein H no signal peptide no TMHs; High confidence in function and specificity; hydrogenase maturation protein HypF	4159390..4161762	Azoarcus sp. BH72	4609059
YP_935304.1	CDS	hypC	NC_008702.1	4161767	4162006	D	Probable hydrogenase assembly chaperon HypC. Homology to hypC of R. leguminosarum of 61% (sprot|HYPC_RHILV). Forms a family of small proteins that are hydrogenase precursor-specific chaperones required for this maturation process. They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation. Pfam: HypF/HypC family Tigrfam: hypC_hupF: hydrogenase assembly chaperone no signal peptide no TMHs; Function unclear; hydrogenase assembly chaperon HypC	4161767..4162006	Azoarcus sp. BH72	4609063
YP_935305.1	CDS	hypD	NC_008702.1	4162003	4163145	D	Hydrogenase expression/formation protein hypD. Homology to hypD of A. eutrophus of 71% (sprot|HYPD_ALCEU). HypD is involved in hydrogenase formation. InterPro: Hydrogenase formation hypA (IPR002780) Pfam: Hydrogenase formation hypA family Tigrfam: hypD: hydrogenase expression/formation no signal peptide no TMHs; High confidence in function and specificity; hydrogenase expression/formation protein HypD	4162003..4163145	Azoarcus sp. BH72	4609060
YP_935306.1	CDS	hypE	NC_008702.1	4163214	4164266	D	Hydrogenase expression/formation protein hypE, 64% Identity to SProt;P31905,TrEMBL;Q6NB52(60% Identity),Q83WU6. Has PF00586, AIR synthase related protein, N-terminal domain;IPR000728 AIR_synth; This family includes Hydrogen expression/formation protein, HypE, which may be involved inthe maturation of NifE hydrogenase; AIR synthase and FGAM synthase, which are involved in de novo purine biosynthesis; and selenide, water dikinase, an enzyme which synthesizes selenophosphate from selenide and ATP. PF02769, AIR synthase related protein, C-terminal domain;IPR010918 AIR_synth_C; This entry includes Hydrogen expression/formation protein, HypE, which may be involved in the maturation of NifE hydrogenase; AIR synthase and FGAM synthase, which are involved in de novo purine biosynthesis; and selenide, water dikinase, an enzyme which synthesizes selenophosphate from selenide and ATP.; hydrogenase expression/formation protein hypE	4163214..4164266	Azoarcus sp. BH72	4609061
YP_935307.1	CDS	hoxA	NC_008702.1	4164280	4165737	D	Hydrogenase transcriptional regulatory protein,; High confidence in function and specificity; hydrogenase transcriptional regulatory protein	4164280..4165737	Azoarcus sp. BH72	4609062
YP_935308.1	CDS	azo3806	NC_008702.1	4165753	4166049	R	Hypothetical protein, 33% Identity to TrEMBL;Q8XRA3 Has No domains, repeats, motifs or features could be predicted above threshold.; hypothetical protein	complement(4165753..4166049)	Azoarcus sp. BH72	4609016
YP_935309.1	CDS	hoxB	NC_008702.1	4166203	4167198	D	Ferredoxin hydrogenase, small subunit. Homology to hoxB of A. hydrogenophilus of 75% (TREMBL:P94154). Hydrogenases catalyse the reversible oxidation of molecular hydrogen and play a vital role in anaerobic metabolism. InterPro: Hydrogenase (NiFe) small subunit HydA (IPR001821); Respiroatory-chain NADH dehydrogenase 20 kD subunit (IPR006137) Tigrfam: hydA: hydrogenase (NiFe) small subunit (hydA) Pfam: NADH ubiquinone oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; ferredoxin hydrogenase small subunit	4166203..4167198	Azoarcus sp. BH72	4608139
YP_935310.1	CDS	hoxC	NC_008702.1	4167356	4168807	D	Probable ferredoxin hydrogenase, large subunit. Homology to hoxC of A. hydrogenophilus of 59% (trembl|P94155). InterPro: Nickel-dependent hydrogenases large subunit; ferredoxin hydrogenase large subunit	4167356..4168807	Azoarcus sp. BH72	4609017
YP_935311.1	CDS	azo3809	NC_008702.1	4168926	4170437	D	Conserved hypothetical membrane protein,; Conserved hypothetical protein; hypothetical protein	4168926..4170437	Azoarcus sp. BH72	4609018
YP_935312.1	CDS	hoxJ	NC_008702.1	4170469	4171854	D	Putative hydrogen uptake histidine-kinase,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR009082; His_kin_homodim. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. Pfam: PF02518; HATPase_c. PF00512; HisKA. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00086; PAC. SM00091; PAS.; High confidence in function and specificity; hydrogen uptake histidine-kinase	4170469..4171854	Azoarcus sp. BH72	4608140
YP_935313.1	CDS	ntaB	NC_008702.1	4171861	4172355	R	Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q7W4Q0: 46% identity, 65% similarity InterPro: Flavin reductase-like domain Interpro:IPR002563 Pfam:PF01613 No signal peptide No transmembrane helices monomer_idh: isocitrate dehydrogenase NA; High confidence in function and specificity; nitrilotriacetate monooxygenase	complement(4171861..4172355)	Azoarcus sp. BH72	4609021
YP_935314.1	CDS	mutY	NC_008702.1	4172470	4173570	D	A/G-specific adenine glycosylase (EC 3.2.2.-). ADENINE GLYCOSYLASE ACTIVE ON G-A MISPAIRS. MUTY ALSO CORRECTS ERROR-PRONE DNA SYNTHESIS PAST GO LESIONS WHICH ARE DUE TO THE OXIDATIVELY DAMAGED FORM OF GUANINE: 78-DIHYDRO-8- OXOGUANINE.; Specificity unclear; putative A/G-specific adenine glycosylase	4172470..4173570	Azoarcus sp. BH72	4609411
YP_935315.1	CDS	azo3813	NC_008702.1	4173767	4174366	R	Conserved hypothetical ATP-dependent protease La. Homology to rsc0402 of R. solanacearum of 44% (trembl|Q8Y2D4). N-terminal domain of the ATP-dependent protease La (LON), present also in other bacterial ORFs. InterPro: ATP-dependent protease La (LON) domain (IPR003111). Pfam: ATP-dependent protease La (LON) domain. no signal peptide. no TMHs; Conserved hypothetical protein; ATP-dependent protease La	complement(4173767..4174366)	Azoarcus sp. BH72	4609298
YP_935316.1	CDS	ubiX	NC_008702.1	4174401	4175030	R	Probable aromatic acid decarboxylase (EC 4.1.1.-). InterPro: Flavoprotein ubiX: phenylacrylic acid decarboxylase; High confidence in function and specificity; aromatic acid decarboxylase	complement(4174401..4175030)	Azoarcus sp. BH72	4608141
YP_935317.1	CDS	azo3815	NC_008702.1	4175247	4175798	D	Probable phasin. Homology to p8 of Sphingomonas sp. A1 of 49% (gi|51773776|dbj|BAD38885.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.,; Function unclear; phasin	4175247..4175798	Azoarcus sp. BH72	4610062
YP_935318.1	CDS	azo3816	NC_008702.1	4175897	4176934	R	Putative AraC family transcriptional regulator,; Family membership; AraC family transcriptional regulator	complement(4175897..4176934)	Azoarcus sp. BH72	4608142
YP_935319.1	CDS	azo3817	NC_008702.1	4177099	4178040	D	Conserved hypothetical protein. Homology to slr1189 of Synechocystis of 43% (trembl|P74718). Pfam: Homocystein S-transferase. no signal peptide. no TMHs.; hypothetical protein	4177099..4178040	Azoarcus sp. BH72	4608143
YP_935320.1	CDS	livK5	NC_008702.1	4178048	4179208	R	In enteric bacteria such as E. coli and Salmonella typhimurium, periplasmic binding proteins are found to participate in the transport of amino acids, sugars and ions. Leucine-specific binding protein are coded by livK and livJ. Similar to sprot|LIVK_SALTY (20%) and to tremblnew|CAE26678 (39%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide.; Specificity unclear; putative leucine-specific binding protein	complement(4178048..4179208)	Azoarcus sp. BH72	4608144
YP_935321.1	CDS	livM6	NC_008702.1	4179274	4180221	R	Putative branched-chain amino acid transporter permease. Homology to livM of E. coli of 32%. Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) Pfam: Branched-chain amino acid transport system. signal peptide probable 10 TMHs; Specificity unclear; putative branched-chain amino acid transport permease	complement(4179274..4180221)	Azoarcus sp. BH72	4609157
YP_935322.1	CDS	azo3820	NC_008702.1	4180301	4181158	R	Branched-chain amino acid transport system typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system.The integral inner-membrane proteins translocate the substrate across the membrane. Similar to trembl|Q89C65 (46%), to sprot|LIVH_ECOLI (33%) and to sprot|BRAD_PSEAE (30%). Pfam (PF02653): Binding-system dependent bacterial transporters (araH, livH/limM families) TMHMM reporting seven Tmhelix. SignalP reporting Signal peptide.; Specificity unclear; ABC transporter permease	complement(4180301..4181158)	Azoarcus sp. BH72	4609163
YP_935323.1	CDS	ncd2	NC_008702.1	4181166	4182143	R	2-nitropropane dioxygenase precursor (EC 1.13.11.32) (Nitroalkane oxidase) (2-NPD). SPROT:Q01284: 28% identity, 44% similarity CATALYZES THE OXIDATION OF NITROALKANES TO PRODUCE THE CORRESPONDING CARBONYL COMPOUNDS. IT ACTS ON 2-NITROPROPANE BETTER THAN ON NITROETHANE AND 1-NITROPROPANE AND ANIONIC FORMS OF NITROALKANES ARE MUCH BETTER SUBSTRATES THAN ARE NEUTRAL FORMS. InterPro: 2-nitropropane dioxygenase InterPro; IPR004136; 2nprop_dioxygen. InterPro; IPR003009; FMN_enzyme. Pfam; PF03060; NPD thiE: thiamine-phosphate pyrophosphoryl Non-secretory protein with signal peptide probability:0.004 Absence of TMH's; High confidence in function and specificity; putative 2-nitropropane dioxygenase	complement(4181166..4182143)	Azoarcus sp. BH72	4608145
YP_935324.1	CDS	mscL	NC_008702.1	4182309	4182734	D	homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel	4182309..4182734	Azoarcus sp. BH72	4609347
YP_935325.1	CDS	ycbL	NC_008702.1	4182759	4183517	R	Hypothetical protein ycbL. TREMBL:Q7P1X5-63% identity. Interpro:IPR001279-Blactamase like Pfam-GlyoxylaseII family relationship. Phosphoribosylglycinamide synthetase,Respiratory chain NADH dehydrogenase; KH domain and RTX toxin acyltransferase family relationship. ispD: 4-diphosphocytidyl-2C-methyl-D-ery; High confidence in function and specificity; hypothetical protein	complement(4182759..4183517)	Azoarcus sp. BH72	4609279
YP_935326.1	CDS	imp	NC_008702.1	4183561	4184352	R	Inositol-1(or4)-monophosphatase 3IMPase3)(IMP3)(Inositol monophosphatase 3).Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. 26% Inositol_P. Pfam:PF00459; Inositol_P; 1.; High confidence in function and specificity; putative inositol monophosphatase	complement(4183561..4184352)	Azoarcus sp. BH72	4610154
YP_935327.1	CDS	fbpA2	NC_008702.1	4184498	4185523	D	Part of the ABC transporter complex FbpABC involved in ferric import. Similar to the putative periplasmic-binding protein FbpA precursor in A. pleuropneumoniae. 39% SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:1 TMHelix:1; Specificity unclear; putative ferric transport system periplasmic-binding protein	4184498..4185523	Azoarcus sp. BH72	4609078
YP_935328.1	CDS	fbpC2	NC_008702.1	4185569	4186576	D	Ferric cations import ATP-binding protein fbpC (EC 3.6.3.30).Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in ferric cations import. Responsible for energy coupling to the transport system. 41% AAA_ATPase. IPR003439; ABC_transporter. Pfam: PF00005;ABC_tran; 1.; Specificity unclear; Fe3+-transporting ATPase	4185569..4186576	Azoarcus sp. BH72	4608731
YP_935329.1	CDS	azo3827	NC_008702.1	4186656	4188308	D	Region start changed from 4186498 to 4186630 (-132 bases); putative ferrric transport system permease	4186656..4188308	Azoarcus sp. BH72	4608734
YP_935330.1	CDS	glpR	NC_008702.1	4188333	4189109	D	Glycerol-3-phosphate regulon repressor. 26% HTH_DeoR. Pfam:PF00455; DeoR; 1. Nucleic acid binding motif, present.; High confidence in function and specificity; putative glycerol-3-phosphate regulon repressor	4188333..4189109	Azoarcus sp. BH72	4608146
YP_935331.1	CDS	eutB	NC_008702.1	4189133	4190521	D	Probable ethanolamine ammonia-lyase (EC 4.3.1.7) large subunit. Homology to eutB of S. typhimurium of 50% (trembl|Q8XUQ9) Catalyzes the deamination of various vicinal amino- alcohols to oxo compounds. no signal peptide no TMHs; High confidence in function and specificity; ethanolamine ammonia-lyase large subunit	4189133..4190521	Azoarcus sp. BH72	4608913
YP_935332.1	CDS	eutC	NC_008702.1	4190532	4191356	D	Ethanolamine ammonia-lyase (EC 4.3.1.7) small subunit. Homology to eutC of S. typhimurium of 35% (sprot|EUTC_SALTY) catalyzes the deamination of various vicinal amino- alcohols to oxo compounds. no signal peptide no TMHs; High confidence in function and specificity; putative ethanolamine ammonia-lyase small subunit	4190532..4191356	Azoarcus sp. BH72	4608686
YP_935333.1	CDS	azo3831	NC_008702.1	4191496	4192371	D	Conserved hypothetical secreted protein. Homology to rpa0361 of R. palustris off 67% (tremblnew|CAE25805). no domains predicted .signal peptide. TMH in signal peptide; Conserved hypothetical protein; hypothetical protein	4191496..4192371	Azoarcus sp. BH72	4608687
YP_935334.1	CDS	azo3832	NC_008702.1	4192520	4193338	R	Putative ABC-type tungstate transport system,permease component.; Function unclear; tungstate ABC transporter permease	complement(4192520..4193338)	Azoarcus sp. BH72	4608147
YP_935335.1	CDS	azo3833	NC_008702.1	4193453	4194556	D	31% HTH_9; 1. InterPro: IPR003725; ModE:Molybdenum-binding protein N-terminal. ModE are involved in molybdenum transport.These proteins acts both as a repressor and activator of the mod and moa operons,respectively, depending on the properties of the binding site.; High confidence in function and specificity; putative molybdenum-binding protein	4193453..4194556	Azoarcus sp. BH72	4608148
YP_935336.1	CDS	azo3834	NC_008702.1	4194613	4195911	R	Conserved hypothetical protein. Homology to vv12967 of V. vulnificus of 47% (trembl|Q8D8K5). Pfam: DUF1111. no signal peptide. no TMHs; hypothetical protein	complement(4194613..4195911)	Azoarcus sp. BH72	4608149
YP_935337.1	CDS	pgtC	NC_008702.1	4195950	4197269	R	Phosphoglycerate transport regulatory protein pgtC precursor.Required for pgtP expression it may act jointly with the pgtA/pgtB signaling proteins.29% SBP_bac_1: Bacterial extracellular solute-binding protein family 1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present.; High confidence in function and specificity; putative regulatory lipoprotein	complement(4195950..4197269)	Azoarcus sp. BH72	4608150
YP_935338.1	CDS	azo3836	NC_008702.1	4197290	4199275	R	Probable Iron-regulated outer membrane TonB-dependent receptor. 35% TonB_receptor.IPR010917; TonB_recept_C.IPR010105; TonB_siderophor. Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide:present.; Function unclear; TonB-dependent receptor	complement(4197290..4199275)	Azoarcus sp. BH72	4609534
YP_935339.1	CDS	modC1	NC_008702.1	4199407	4200564	R	80% AAA_ATPase superfamily. IPR003439; ABC_transporter. IPR008995; MOP_like:molybdenum-pterin binding domain.IPR005116; TOBE. Pfam:PF00005; ABC_tran; 1.PF03459; TOBE; 1.; High confidence in function and specificity; putative molybdenum transport system ATP-binding protein	complement(4199407..4200564)	Azoarcus sp. BH72	4608151
YP_935340.1	CDS	modB1	NC_008702.1	4200561	4201241	R	72% BPD_transp.Binding-protein-dependent transport systems inner membrane component. Pfam:PF00528; BPD_transp; 1. TMHelix:6; High confidence in function and specificity; putative molybdenum transport system permease	complement(4200561..4201241)	Azoarcus sp. BH72	4609252
YP_935341.1	CDS	modA1	NC_008702.1	4201261	4202022	R	73% MolP_ABC_transpt.IPR000437; prok_lipoprot_S. IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR01256; modA; 1. Signal peptide: present.; High confidence in function and specificity; putative molybdate transport system periplasmic-binding protein	complement(4201261..4202022)	Azoarcus sp. BH72	4609250
YP_935342.1	CDS	modE	NC_008702.1	4202077	4202904	R	80% ModE.IPR004606; Mop.IPR008995; MOP_like.IPR005116; TOBE.Molybdenum-binding protein N-terminal. Pfam:PF02573; HTH_9; 1.PF03459; TOBE; 2. TIGRFAMs:TIGR00637; ModE_repress; 1:ModE molybdate transport.TIGR00638; Mop; 2.; High confidence in function and specificity; putative molybdenum transport protein	complement(4202077..4202904)	Azoarcus sp. BH72	4609248
YP_935343.1	CDS	modG	NC_008702.1	4203085	4203513	D	80% Mop.IPR008995;MOP_like.IPR005116;TOBE.InterPro: Molybdenum-pterin binding domain. Mop: molybdenum-pterin binding domain Pfam: PF03459; TOBE; 2. TIGRFAMs:TIGR00638; Mop; 2.; High confidence in function and specificity; putative molybdenum-pterin-binding-protein	4203085..4203513	Azoarcus sp. BH72	4609255
YP_935344.1	CDS	modC2	NC_008702.1	4203575	4204612	D	39% AAA_ATPase superfamily. IPR003439; ABC_transporter. IPR008995; MOP_like:molybdenum-pterin binding domain.IPR005116; TOBE. Pfam:PF00005; ABC_tran; 1.PF03459; TOBE; 1.; High confidence in function and specificity; putative molybdate transport system ATP-binding protein	4203575..4204612	Azoarcus sp. BH72	4609256
YP_935345.1	CDS	azo3843	NC_008702.1	4204593	4205462	R	Putative exported protein.SignalP reporting signal peptice. Most likely cleavage site between pos. 27 and 28: AHA-AP; Function unclear; hypothetical protein	complement(4204593..4205462)	Azoarcus sp. BH72	4609253
YP_935346.1	CDS	azo3844	NC_008702.1	4205489	4207765	R	Region start changed from 4207859 to 4207739 (-120 bases); putative TonB-dependent receptor	complement(4205489..4207765)	Azoarcus sp. BH72	4608152
YP_935347.1	CDS	modB2	NC_008702.1	4208004	4208693	R	36% BPD_transp.Binding-protein-dependent transport systems inner membrane component. Pfam:PF00528; BPD_transp; 1. TMHelix:5 Signal peptide:present; High confidence in function and specificity; putative molybdenum ABC transporter permease	complement(4208004..4208693)	Azoarcus sp. BH72	4608153
YP_935348.1	CDS	modA2	NC_008702.1	4208693	4209478	R	23% MolP_ABC_transpt.IPR000437; prok_lipoprot_S. IPR006059; SBP_bac_1. Pfam:PF01547; SBP_bac_1; 1. TIGRFAMs:TIGR01256; modA; 1. Signal peptide: present.; High confidence in function and specificity; putative molybdate transport system substrate-binding protein	complement(4208693..4209478)	Azoarcus sp. BH72	4609251
YP_935349.1	CDS	azo3847	NC_008702.1	4209537	4209923	R	conserved hypothetical protein. Homology to Daro03003735 of Dechloromonas aromatica of 35% (gi|41722661|ref|ZP_00149650.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMHs.; hypothetical protein	complement(4209537..4209923)	Azoarcus sp. BH72	4609249
YP_935350.1	CDS	yhjG	NC_008702.1	4210313	4212361	D	Function unclear; outer membrane protein	4210313..4212361	Azoarcus sp. BH72	4608154
YP_935351.1	CDS	azo3849	NC_008702.1	4212375	4214444	R	GGDEF/EAL/PAS/PAC-domain containing protein; diguanylate cyclase	complement(4212375..4214444)	Azoarcus sp. BH72	4610183
YP_935352.1	CDS	recD	NC_008702.1	4214513	4216465	R	Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) (Exodeoxyribonuclease V 67 kDa polypeptide). EXHIBITS SEVERAL CATALYTIC ACTIVITIES INCLUDING ATP-DEPENDENT EXONUCLEASE ATP-STIMULATED ENDONUCLEASE ATP-DEPENDENT UNWINDING AND DNA-DEPENDENT ATPASE ACTIVITIES. STRAND CLEAVAGE OCCURS 5 TO 3 DURING THE UNWINDING OF DUPLEX DNA AT CHI SEQUENCES WHICH LOCALLY STIMULATE RECOMBINATION. InterPro: AAA ATPase superfamily; High confidence in function and specificity; DNA helicase	complement(4214513..4216465)	Azoarcus sp. BH72	4608155
YP_935353.1	CDS	recB	NC_008702.1	4216462	4220187	R	Exodeoxyribonuclease V beta chain (EC 3.1.11.5) (Exodeoxyribonuclease V 135 KDA polypeptide). REQUIRED FOR EFFICIENT DNA REPAIR; IT CATALYZES THE UNWINDING OF DOUBLE-STRANDED DNA AND THE CLEAVAGE OF SINGLE- STRANDED DNA AND IT STIMULATES LOCAL GENETIC RECOMBINATION. ALL OF THESE ACTIVITIES REQUIRE CONCOMITANT HYDROLYSIS OF ATP.; High confidence in function and specificity; ATP-dependent exoDNAse subunit beta	complement(4216462..4220187)	Azoarcus sp. BH72	4609705
YP_935354.1	CDS	irgA2	NC_008702.1	4220373	4222526	D	24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present.; High confidence in function and specificity; putative TonB-dependent receptor	4220373..4222526	Azoarcus sp. BH72	4609703
YP_935355.1	CDS	azo3853	NC_008702.1	4222614	4223768	D	Conserved hypothetical protein; Function unclear; hypothetical protein	4222614..4223768	Azoarcus sp. BH72	4609088
YP_935356.1	CDS	ligT	NC_008702.1	4223747	4224304	D	2-5 RNA ligase (EC 6.5.1.-). Specifically ligates tRNA half-molecules containing nucleoside base modifications and shows a preference among different tRNA species. Acts in the absence of ATP to form a 2-5 phosphodiester linkage.; 2'-5' RNA ligase	4223747..4224304	Azoarcus sp. BH72	4608156
YP_935357.1	CDS	azo3855	NC_008702.1	4224451	4226037	D	Alkaline phosphatase (EC 3.1.3.1) (ALP)is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.It is found in nearly all living organisms,with the exception of some plants. 30% Alk_phosphtse.Alkaline phosphatase family Pfam:PF00245; alk_phosphatase; 1. Signal peptide present.; High confidence in function and specificity; putative alkaline phosphatase	4224451..4226037	Azoarcus sp. BH72	4609145
YP_935358.1	CDS	azo3856	NC_008702.1	4226137	4226919	D	Conserved hypothetical secreted protein. Homology to Avin02002740 of Azotobacter vinelandii of 66% (gi|23103854|ref|ZP_00090328.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHS; Conserved hypothetical protein; hypothetical protein	4226137..4226919	Azoarcus sp. BH72	4608157
YP_935359.1	CDS	paaG6	NC_008702.1	4226936	4227793	R	Function:- Could possibly oxidizes fatty acids using specific components (By similarity). Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 65/222 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; putative enoyl-CoA hydratase paaG	complement(4226936..4227793)	Azoarcus sp. BH72	4608158
YP_935360.1	CDS	recC	NC_008702.1	4227790	4231209	R	Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) (Exodeoxyribonuclease V 125 kDa polypeptide). EXHIBITS A WIDE VARIETY OF CATALYTIC ACTIVITIES INCLUDING ATP-DEPENDENT EXONUCLEASE ATP-STIMULATED ENDONUCLEASE ATP-DEPENDENT HELICASE AND DNA-DEPENDENT ATPASE ACTIVITIES.; High confidence in function and specificity; DNA helicase	complement(4227790..4231209)	Azoarcus sp. BH72	4609477
YP_935361.1	CDS	yeaT	NC_008702.1	4231262	4232182	R	Putative transcriptional regulator, LysR family,; High confidence in function and specificity; LysR family transcriptional regulator	complement(4231262..4232182)	Azoarcus sp. BH72	4609704
YP_935362.1	CDS	yeaU	NC_008702.1	4232582	4233661	D	Tartrate dehydrogenase catalyzes the reduction of tartrate to oxaloglycolate. Similar to sprot|TTUC_ECOLI (75%) and to sprot|TTUC_PSEPU (76%). Pfam (PF00180): Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity; tartrate dehydrogenase	4232582..4233661	Azoarcus sp. BH72	4610167
YP_935363.1	CDS	azo3861	NC_008702.1	4233743	4233961	R	Hypothetical protein, 73% identity(87% similarity) to TrEMBL;Q8XU60. No domains, repeats, motifs or features not present.; Function unclear; hypothetical protein	complement(4233743..4233961)	Azoarcus sp. BH72	4610168
YP_935364.1	CDS	azo3862	NC_008702.1	4234040	4234657	R	Conserved hypothetical membrane protein. Homology to rsc2949 of R. solanacearum of 54% (trembl|Q8XV82(SRS)). Tigrfam: TIGR00427: conserved hypothetical protein. Pfam: Uncharacterised protein family. signal peptide. 5 TMHs; hypothetical protein	complement(4234040..4234657)	Azoarcus sp. BH72	4608159
YP_935365.1	CDS	azo3863	NC_008702.1	4234851	4236512	D	Conserved hypothetical protein. Homology to ebA2737 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA2737(KEGG)). no domains predicted. no signal peptide. no TMHs; hypothetical protein	4234851..4236512	Azoarcus sp. BH72	4608160
YP_935366.1	CDS	azo3864	NC_008702.1	4236519	4236902	R	Conserved hypothetical cytochrome c family protein. Homology to gsu2513 of G. sulfurreducens of 36% (tremblnew|AAR35886). Pfam: Cytochrome c. singal peptide. no TMHs; Conserved hypothetical protein; cytochrome c family protein	complement(4236519..4236902)	Azoarcus sp. BH72	4608161
YP_935367.1	CDS	exaA5	NC_008702.1	4236962	4238632	R	Quinoprotein ethanol dehydrogenase precursor (QEDH). Oxidizes primary alcohols and also acts on secondary alcohol, but not highly active on methanol. 32% Bac_PQQ.IPR002372; Bac_PQQ_repeat. Pfam:PF01011; PQQ; 2. Signal peptide:present. SWISSPROT:DHET_GLUOX:O05542.30%; High confidence in function and specificity; putative quinoprotein ethanol dehydrogenase	complement(4236962..4238632)	Azoarcus sp. BH72	4608162
YP_935368.1	CDS	azo3866	NC_008702.1	4238668	4239555	R	Conserved hypothetical secreted protein. Homology to GOX0515 of Gluconobacter oxydans of 36% (gnl|keqq|gox:GOX0515(KEGG)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(4238668..4239555)	Azoarcus sp. BH72	4608693
YP_935369.1	CDS	acoA2	NC_008702.1	4239989	4240999	D	Probable acetoin dehydrogenase, alpha subunit. Homology to acoA of C. magnum of 42% (trembl|Q46142) CATALYZES THE 26-DICHLOROPHENOLINDOPHENOL-DEPENDENT CLEAVAGE OF ACETOIN INTO ACETATE AND ACETALDEHYDE IN VITRO. THE ALPHA SUBUNIT IS PROBABLY THE CATALYTIC SUBUNIT OF THE ENZYME. Pfam: Dehydrogenase E1 component no signal peptide no TMHs; Family membership; acetoin dehydrogenase subunit alpha	4239989..4240999	Azoarcus sp. BH72	4608163
YP_935370.1	CDS	acoB2	NC_008702.1	4241016	4242053	D	Probable acetoin dehydrogenase, beta subunit. Homology to acoB of. A. eutrophus of 48% (sprot|ACOB_ALCEU) Probable TPP-dependent acetoin dehydrogenase, beta subunit. Homology to acoB of A. eutrophus of 41% (sprot|ACOB_ALCEU) Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde, in vitro. The beta subunit is probably not the catalytic subunit of the enzyme. InterPro: Transketolase (IPR005474) Pfam: Transketoase,pyridine binding domain ; Transketolase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity; acetoin dehydrogenase subunit beta	4241016..4242053	Azoarcus sp. BH72	4608266
YP_935371.1	CDS	azo3869	NC_008702.1	4242264	4242509	D	Conserved hypothetical protein. Homology to oadh21d of H. volcanii of 33% (trembl|Q8U4T3). Pfam: Biotin-requiring enzyme. Interpro: Biotin/Lipoyl attachment (IPR000089). no signal peptide. no TMHs.; hypothetical protein	4242264..4242509	Azoarcus sp. BH72	4608268
YP_935372.1	CDS	azo3870	NC_008702.1	4242513	4243226	D	Hypothetical protein. Homology of the entire orf to the C-terminus of dihydrolipoamide acetyltransferase. Pfam: 2-0xo acid dehydrogenase acyltransferase no TMHs no signal peptide; hypothetical protein	4242513..4243226	Azoarcus sp. BH72	4608164
YP_935373.1	CDS	azo3871	NC_008702.1	4243226	4243996	D	Putative lipoate protein ligase, has weak homology with hits. 35% identity with TrEMBL;Q81M24,Q818P0. Has Signal peptide. Has PF03099, Biotin/lipoate A/B protein ligase family;IPR004143 BPL_LipA_LipB; This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organism probably has only one BPL. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LPLA) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes.; putative lipoate protein ligase	4243226..4243996	Azoarcus sp. BH72	4608165
YP_935374.1	CDS	azo3872	NC_008702.1	4244062	4244643	D	Conserved hypothetical secreted protein. Homology blr7490 of B.japonicum of 47% (trembl|Q89DE9(SRS)). No domains predicted .No TMHs. Signal peptide: present; Conserved hypothetical protein; hypothetical protein	4244062..4244643	Azoarcus sp. BH72	4608166
YP_935375.1	CDS	azo3873	NC_008702.1	4244733	4246307	D	Putative glucase dehydrogenase alpha subunit. Homology to gdhalspha of B. cepacia of 31% (trembl|Q8GQE7). Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear; putative glucase dehydrogenase subunit alpha	4244733..4246307	Azoarcus sp. BH72	4608167
YP_935376.1	CDS	azo3874	NC_008702.1	4246369	4246983	D	Conserved hypothetical secreted protein.; Conserved hypothetical protein; hypothetical protein	4246369..4246983	Azoarcus sp. BH72	4608168
YP_935377.1	CDS	azo3875	NC_008702.1	4247215	4249182	D	Similar to SWISSPROT:P28614 (44% identity); TREMBL:Q9HWN4 (40% identity); TREMBL:Q92X60 (38% identity). Pfam (PF02954): Bacterial regulatory protein,Fis family. Pfam (PF00158): Sigma-54 interaction domain. HTH reporting nucleic acid binding motif.; Family membership; sigma-54-dependent transcriptional regulator	4247215..4249182	Azoarcus sp. BH72	4608169
YP_935378.1	CDS	azo3876	NC_008702.1	4249321	4251393	D	Rhs family protein,vgrG 38% identity(54% similarity) to TrEMBL;Q747T8. TrEMBL;O52672. Signal Peptide Present. Has PF04524, Protein of unknown function,DUF586;IPR006533, Rhs_Vgr:This family contains a conserved region in several bacterial proteins of unknown function. These sequences represent the Vgr family of proteins,associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region,VGXXXXXX, found in the Vgr of Rhs classes G and E. Has PF06715, Gp5 C-terminal repeat (2 copies);IPR010609,Gp5_C:This repeat composes the C-terminal part of the bacteriophage T4 baseplate protein Gp5. This region of the protein forms a needle like projection from the baseplate that is presumed to puncture the bacterial cell membrane. Structurally three copies of the repeated region trimerise to form a beta solenoid type structure. This family also includes repeats from bacterial Vgr proteins.; hypothetical protein	4249321..4251393	Azoarcus sp. BH72	4608170
YP_935379.1	CDS	azo3877	NC_008702.1	4251398	4252432	D	Conserved hypothetical protein. Homology to GSU3186 of G.sulfurreducens of 36% (tremblnew|AAR36577(SRS)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	4251398..4252432	Azoarcus sp. BH72	4608171
YP_935380.1	CDS	azo3878	NC_008702.1	4252437	4253474	D	Region start changed from 4252363 to 4252411 (-48 bases); hypothetical protein	4252437..4253474	Azoarcus sp. BH72	4608172
YP_935381.1	CDS	azo3879	NC_008702.1	4253497	4254504	D	Hypothetical protein predicted by Glimmer/Critica. no homology of the entier protein to the data bank. no domains predicted. no signal peptide. no TMHs; hypothetical protein	4253497..4254504	Azoarcus sp. BH72	4608173
YP_935382.1	CDS	azo3880	NC_008702.1	4254527	4255069	D	Hypothetical protein. Homology to LA1152 of L.interrogans of 28% (trembl:Q8F6Z6). No domains predicted. No signal peptide. No TMHs; hypothetical protein	4254527..4255069	Azoarcus sp. BH72	4608174
YP_935383.1	CDS	azo3881	NC_008702.1	4255159	4255536	D	Conserved hypothetical protein. Homology to GSU3182 of G.sulfurreducens of 42% (tremblnew|AAR36573(SRS)). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	4255159..4255536	Azoarcus sp. BH72	4608175
YP_935384.1	CDS	azo3882	NC_008702.1	4255546	4255974	D	Hypothetical protein, 40% similarity to TrEMBL: O86588. No domains, repeats, motifs or features predicted present.; Function unclear; hypothetical protein	4255546..4255974	Azoarcus sp. BH72	4608176
YP_935385.1	CDS	azo3883	NC_008702.1	4255979	4257190	D	Hypothetical protein,35% identity(53% similarity) to TrEMBL;Q9I731. Very Poor homology with hits in the database over the entire length of protein! No Signal peptide or TMH reported Present.; Family membership; hypothetical protein	4255979..4257190	Azoarcus sp. BH72	4608177
YP_935386.1	CDS	azo3884	NC_008702.1	4257210	4259045	D	Hypothetical regulatory protein,; Conserved hypothetical protein; regulatory protein	4257210..4259045	Azoarcus sp. BH72	4608178
YP_935387.1	CDS	azo3885	NC_008702.1	4259097	4259867	D	Putative phosphoprotein phosphatase,; Conserved hypothetical protein; putative phosphoprotein phosphatase	4259097..4259867	Azoarcus sp. BH72	4608179
YP_935388.1	CDS	azo3886	NC_008702.1	4259941	4260594	D	Hypothetical secreted protein. Homology to cv1891 of C. violaceum of 27% (TrEMBL:Q7NWT8). no domains predicted. signal peptide. no TMHs; hypothetical protein	4259941..4260594	Azoarcus sp. BH72	4608180
YP_935389.1	CDS	azo3887	NC_008702.1	4260635	4261894	D	Hypothetical secreted protein. no Homology of the entiere protein to the data bank. no domains predicted. singal peptide. no TMHs; hypothetical protein	4260635..4261894	Azoarcus sp. BH72	4608181
YP_935390.1	CDS	azo3888	NC_008702.1	4261940	4263946	R	Serine/threonine-protein kinase pknA (EC 2.7.11.1). Probably required for both normal cellular growth and differentiation. Inactivation of pknA leads to colonies that appear light green and rough in the absence of combined nitrogen. Pfam: Protein kinase domain; Family membership; putative serine/threonine kinase	complement(4261940..4263946)	Azoarcus sp. BH72	4608182
YP_935391.1	CDS	azo3889	NC_008702.1	4264005	4264706	R	Conserved hypothetical protein. Homology to PA0076 of P.aeruginosa of 38% (trembl:Q9I756). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(4264005..4264706)	Azoarcus sp. BH72	4608183
YP_935392.1	CDS	imcF	NC_008702.1	4264709	4268281	R	Conserved hypothetical ImcF-related protein. Homology to BPP0730 of Bordetella parapertussis of 45% (gnl|keqq|bpa:BPP0730(KEGG)). Has Signal Peptide. TMHMM2 reporting 2 TMH's present. Coils2 Program reporting presence of Coiled-Coil. Has PF06761, ImcF-related;IPR009612; This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical proteins. Has PF06744, Protein of unknown function (DUF1215);IPR010623; This family represents a conserved region situated towards the C-terminal end of several hypothetical bacterial proteins of unknown function. A few members resemble the ImcF protein, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation that results in increased adherence to epithelial cells line and increased conjugation frequency.; Conserved hypothetical protein; ImcF-like protein	complement(4264709..4268281)	Azoarcus sp. BH72	4608184
YP_935393.1	CDS	ompA2	NC_008702.1	4268313	4269617	R	Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms.; Conserved hypothetical protein; hypothetical protein	complement(4268313..4269617)	Azoarcus sp. BH72	4609077
YP_935394.1	CDS	impJ	NC_008702.1	4269682	4271016	R	Conserved hypothetical protein,40% Identity (57% similarity)to TrEMBL;Q93EC4 Has PF05936, Bacterial protein of unknown function (DUF876);IPR010263;This family consists of a series of hypothetical bacterial sequences of unknown function.; hypothetical protein	complement(4269682..4271016)	Azoarcus sp. BH72	4609444
YP_935395.1	CDS	azo3893	NC_008702.1	4271065	4271583	R	Conserved hypothetical secreted protein. Homology to PA1666 of P.aeruginosa of 37% (trembl|Q9I359(SRS)). Signal peptide present. No TMH or any other domains/features reported present.; Conserved hypothetical protein; hypothetical protein	complement(4271065..4271583)	Azoarcus sp. BH72	4609079
YP_935396.1	CDS	sciA	NC_008702.1	4271852	4272913	D	Putative cytoplasmic protein,sciA. TrEMBL;Q83SK5 ,Q7AXZ5 Has PF06812, ImpA-related N-terminal;IPR010657,ImpA_N;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins.; Conserved hypothetical protein; putative cytoplasmic protein	4271852..4272913	Azoarcus sp. BH72	4608185
YP_935397.1	CDS	sciH	NC_008702.1	4272962	4273471	D	Putative cytoplasmic protein,sciH, 71% identity(87% similarity) to TrEMBL;Q7AXZ1. Has PF05591, Protein of unknown function (DUF770);IPR008312,UCP028301;This family consists of several proteins of unknown function from various bacterial species. These proteins are encoded in pathogenic and symbiotic bacteria as part of an operon (part of the SCI genomic island in Salmonella enterica and the imp locus in Rhizobium leguminosarum) implicated in pathogenicity and protein secretion.These proteins are SciH/ImpB.; High confidence in function and specificity; hypothetical protein	4272962..4273471	Azoarcus sp. BH72	4609843
YP_935398.1	CDS	sciI	NC_008702.1	4273523	4275019	D	Putative cytoplasmic protein, sciI, 68% identity(80% similarity) to TrEMBL;Q93IS7. Has PF05943,Protein of unknown function (DUF877);IPR010269;This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown.; High confidence in function and specificity; hypothetical protein	4273523..4275019	Azoarcus sp. BH72	4609848
YP_935399.1	CDS	sciM	NC_008702.1	4275148	4275636	D	Putative cytoplasmic protein,sciM , 33% identity(50% similarity) to TrEMBL;Q7AXY8. Has PF05638,Protein of unknown function (DUF796);IPR008514;This family consists of several bacterial proteins of unknown function.; High confidence in function and specificity; hypothetical protein	4275148..4275636	Azoarcus sp. BH72	4609849
YP_935400.1	CDS	sciK	NC_008702.1	4275831	4276337	D	Putative cytoplasmic protein,sciK, 33% identity to TrEMBL;Q7AXZ0. Has PF05638, Protein of unknown function (DUF796);This family consists of several bacterial proteins of unknown function. Signal Peptide or TMH absent.; Conserved hypothetical protein; hypothetical protein	4275831..4276337	Azoarcus sp. BH72	4609851
YP_935401.1	CDS	sciE	NC_008702.1	4276353	4277174	D	Putative cytoplasmic protein,sciE, 37% identity(52% similarity) to TrEMBL;Q93IT1. Has PF07024, ImpE protein;This family consists of several bacterial proteins including ImpE (Q93EC9) from Rhizobium leguminosarum. It has been suggested that the imp locus is involved in the secretion to the environment of proteins, including periplasmic RbsB protein, that cause blocking of infection specifically in pea plants.The exact function of this family is unknown.; High confidence in function and specificity; hypothetical protein	4276353..4277174	Azoarcus sp. BH72	4609850
YP_935402.1	CDS	sciD	NC_008702.1	4277167	4277676	D	Putative cytoplasmic protein, sciD,34% identity (50% similarity) to TrEMBL; Q7AXZ4. Has PF07025, Protein of unknown function (DUF1316);IPR010745;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein	4277167..4277676	Azoarcus sp. BH72	4609847
YP_935403.1	CDS	sciC	NC_008702.1	4277775	4279646	D	Putative cytoplasmic protein, sciC, 42% identity (57% similarity) to TrEMBL; Q93IT3. Has PF05947, Bacterial protein of unknown function (DUF879);IPR010272 ; This family consists of several hypothetical bacterial proteins of unknown function.; Function unclear; hypothetical protein	4277775..4279646	Azoarcus sp. BH72	4609846
YP_935404.1	CDS	sciB	NC_008702.1	4279622	4280665	D	Putative cytoplasmic protein, sciB. TrEMBl;Q93IT4(36% identity) Has PF06996;Protein of unknown function (DUF1305);IPR010732 ;This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence.; Conserved hypothetical protein; hypothetical protein	4279622..4280665	Azoarcus sp. BH72	4609845
YP_935405.1	CDS	clpB2	NC_008702.1	4280714	4283434	D	Putative ATP-dependent Clp protease, ATP-binding subunit ClpB. Homology to clpB of E. coli of 38% (sprot|CLPB_ECOLI). The protein is thought to be subunits of ATP-dependent proteases which act as chaperones to target the proteases to substrates. Pfam: ATPsae family associated with various cellular activites no signal peptide no TMHs; High confidence in function and specificity; putative ATP-dependent Clp protease, ATP-binding subunit ClpB	4280714..4283434	Azoarcus sp. BH72	4609844
YP_935406.1	CDS	azo3904	NC_008702.1	4283535	4283924	D	Hypothetical protein predicted by Glimmer/Critica no homology of the entire protein to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	4283535..4283924	Azoarcus sp. BH72	4608488
YP_935407.1	CDS	azo3905	NC_008702.1	4283936	4285093	D	Entry name:- TREMBL:Q7MFV5 Identities = 112/345 (32%), InterPro:- IPR002921; Lipase_3. Pfam:- PF01764; Lipase_3; 1. Prediction: Non-secretory protein Signal peptide probability: 0.074 Number of predicted TMHs: 0; Family membership; putative lipase family protein	4283936..4285093	Azoarcus sp. BH72	4608186
YP_935408.1	CDS	azo3906	NC_008702.1	4285131	4286267	D	Hypothetical protein. No homology over the entire length with the data base. Pfam: Phosphatidylinositol-specific phospholipase C, X domain. Interpro: Phosphatidylinositol-specific phospholipase C, X region (IPR000909). No TMHs. No signal peptide.; hypothetical protein	4285131..4286267	Azoarcus sp. BH72	4608187
YP_935409.1	CDS	azo3907	NC_008702.1	4286286	4287635	D	Conserved hypothetical protein. Homology to xac4125 of X. axonopodis of 42% (trembl|Q8PF60). Domain structure: 5 x TRP, 50 aa - 83 aa; 84 aa - 117 aa; 118 aa - 151 aa; 152 aa - 182 aa; 186 aa - 219 aa. InterPro: TPR repeat (IPR001440); SAM (and some other nucleotide) binding motif (IPR000051). Pfam: TPR daomian. no signal peptide. no TMHs; hypothetical protein	4286286..4287635	Azoarcus sp. BH72	4608188
YP_935410.1	CDS	azo3908	NC_008702.1	4287636	4289066	R	PutativeSerine/threonine-protein kinase (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine protein kinase 2). Seems to act exclusively upon threonine residues. Pfam: Protein kinase domain; Family membership; putative serine/threonine protein kinase	complement(4287636..4289066)	Azoarcus sp. BH72	4608189
YP_935411.1	CDS	mnsA	NC_008702.1	4289077	4289949	R	Probable sensor protein,; High confidence in function and specificity; sensor protein	complement(4289077..4289949)	Azoarcus sp. BH72	4608190
YP_935412.1	CDS	azo3910	NC_008702.1	4290002	4290928	R	Hypothetical secreted protein no homology of the entire protein to the data bank no domains predicted signal peptide no TMHs; hypothetical protein	complement(4290002..4290928)	Azoarcus sp. BH72	4609233
YP_935413.1	CDS	fabF2	NC_008702.1	4291053	4292258	D	FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase	4291053..4292258	Azoarcus sp. BH72	4608191
YP_935414.1	CDS	azo3912	NC_008702.1	4292263	4293090	D	Conserved hypothetical protein. Homology to RSc0426 of R.solanacearum of 51% (trembl:Q8Y2B0). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	4292263..4293090	Azoarcus sp. BH72	4608710
YP_935415.1	CDS	azo3913	NC_008702.1	4293087	4293596	D	Entry name:- TREMBL:Q8Y2B1 Prim. accession # Q8Y2B1 Identities = 64/116 (55%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; hypothetical protein	4293087..4293596	Azoarcus sp. BH72	4608192
YP_935416.1	CDS	fabG	NC_008702.1	4293607	4294332	D	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase	4293607..4294332	Azoarcus sp. BH72	4608193
YP_935417.1	CDS	azo3915	NC_008702.1	4294332	4295636	D	23% K_eff.IPR006153; Na_H_porter. Pfam:PF00999; Na_H_Exchanger; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix: 11.; High confidence in function and specificity; putative Na/H(+) antiporter	4294332..4295636	Azoarcus sp. BH72	4608712
YP_935418.1	CDS	argC	NC_008702.1	4295751	4296674	D	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase	4295751..4296674	Azoarcus sp. BH72	4608194
YP_935419.1	CDS	azo3917	NC_008702.1	4296699	4297466	R	Specificity unclear; glycosyltransferase	complement(4296699..4297466)	Azoarcus sp. BH72	4608333
YP_935420.1	CDS	azo3918	NC_008702.1	4297495	4298283	R	Putative phospholipid biosynthesis acyltransferase,30% Identity to TrEMBL;Q8FJ00.Q8X6N6 Has Signal Peptide. Has SMART;SM00563, PlsC, Phosphate acyltransferases;Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.; putative phospholipid biosynthesis acyltransferase	complement(4297495..4298283)	Azoarcus sp. BH72	4608195
YP_935421.1	CDS	mipA	NC_008702.1	4298304	4299155	R	MltA-interacting protein precursor. MAY SERVE AS A SCAFFOLD PROTEIN REQUIRED FOR THE FORMATION OF A COMPLEX WITH MRCB/PONB AND MLTA THIS COMPLEX COULD PLAY A ROLE IN ENLARGEMENT AND SEPTATION OF THE MUREIN SACCULUS.; High confidence in function and specificity; MltA-interacting protein	complement(4298304..4299155)	Azoarcus sp. BH72	4608196
YP_935422.1	CDS	azo3920	NC_008702.1	4299152	4300162	R	Conserved Hypothetical protein, Most Hits in the data base suggest to Pteridine-dependent deoxygenase like protein,TrEMBL;Q8P3Q5. Has PF01042 Endoribonuclease L-PSP,(IPR006175:Endoribon_LPSP);This domain is found in endoribonuclease, that is active on single-stranded mRNA and inhibits protein synthesis by cleavage of mRNA. Previously it was thought to inhibit protein synthesis initiation.This endoribonuclease may also be involved in the regulation of purine biosynthesis . No Signal peptide or TMH present!; Family membership; hypothetical protein	complement(4299152..4300162)	Azoarcus sp. BH72	4609225
YP_935423.1	CDS	azo3921	NC_008702.1	4300159	4301538	R	Conserved hypothetical protein. Homology to xcc4013 of X. campestris of 46% (trembl|Q8P3Q6). InterPro: Monooxygenases FAD binding domain (IPR002938); NAD binding site (IPR000205) Pfam: FAD binding domain; Monooxygenase FAD binding domain. no signal peptide. no TMHs; hypothetical protein	complement(4300159..4301538)	Azoarcus sp. BH72	4608197
YP_935424.1	CDS	azo3922	NC_008702.1	4301535	4302155	R	Conserved hypothetical secred protein. Homology to xac4267 of X. axonopodis of 41% (trembl|Q8PES3). no domains predicted .signal peptide. no TMHs; Conserved hypothetical protein; hypothetical protein	complement(4301535..4302155)	Azoarcus sp. BH72	4608198
YP_935425.1	CDS	lrp2	NC_008702.1	4302273	4302821	R	Probable leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (49% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif.; High confidence in function and specificity; leucine-responsive regulatory protein	complement(4302273..4302821)	Azoarcus sp. BH72	4608199
YP_935426.1	CDS	dadA2	NC_008702.1	4302926	4304239	D	catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit	4302926..4304239	Azoarcus sp. BH72	4609181
YP_935427.1	CDS	alr	NC_008702.1	4304301	4305362	D	Alanine racemase catabolic (EC 5.1.1.1). Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by dadA (By similarity). alr: alanine racemase; High confidence in function and specificity; alanine racemase	4304301..4305362	Azoarcus sp. BH72	4608579
YP_935428.1	CDS	azo3926	NC_008702.1	4305381	4305590	R	conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH; hypothetical protein	complement(4305381..4305590)	Azoarcus sp. BH72	4608306
YP_935429.1	CDS	cycH	NC_008702.1	4305599	4306858	R	Conserved hyppthetical cytochrome c-type biogenesis protein CycH. Homology to cycH of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA3526(KEGG)). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE (BY SIMILARITY). signal peptide. 1 TMHs; Conserved hypothetical protein; cytochrome c-type biogenesis protein CycH	complement(4305599..4306858)	Azoarcus sp. BH72	4608200
YP_935430.1	CDS	cycL	NC_008702.1	4306855	4307364	R	Probable Cytochrome c-type biogenesis protein cycL. Homology to cycL of S. meliloti of 44% (sprot|CCMH_RHIME). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. signal peptide probable 2 TMHs; Family membership; cytochrome C-type biogenesis protein CycL	complement(4306855..4307364)	Azoarcus sp. BH72	4608550
YP_935431.1	CDS	ccmG	NC_008702.1	4307381	4307974	R	Probable thiol disulfide interchange protein. Involved in disulfide bond formation. Catalyzes a late reductive step in the assembly of periplasmic c-type cytochromes probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity). InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE (IPR004799) Interpro: Thioredoxin (IPR006662) Tigrfam: dsbE: periplasmic protein thiol:disulfide axidoreductase, DsbE superfamily signal peptide Probable 1 TMH; Family membership; protein disulfide-isomerase	complement(4307381..4307974)	Azoarcus sp. BH72	4608551
YP_935432.1	CDS	ccmF	NC_008702.1	4307994	4309970	R	Cytochrome c-type biogenesis protein ccmF. Homology to ccmF of E. coli of 63% (sprot|CCMF_ECOLI). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. Tigrfam: nerF: cytochrome c-type biogenesis protein ccmF Pfam: Cytochrome C assembly protein probably signal peptide probably 15 THMs; High confidence in function and specificity; cytochrome c-type biogenesis protein CcmF	complement(4307994..4309970)	Azoarcus sp. BH72	4608450
YP_935433.1	CDS	ccmE	NC_008702.1	4309967	4310413	R	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE	complement(4309967..4310413)	Azoarcus sp. BH72	4608449
YP_935434.1	CDS	ccmD	NC_008702.1	4310410	4310631	R	Conserved hypothetical heme exporter protein D. Homology to ccmD of Azoarcus EBN1 of 49% (trembl:Q5P3K7). Pfam: Heme exporter protein D . The CcmD protein is part of a C-type cytochrome biogenesis operon. The exact function of this protein is uncertain. It has been proposed that CcmC, CcmD and CcmE interact directly with each other, establishing a cytoplasm to periplasm haem delivery pathway for cytochrome c maturation. This protein is found fused to CcmE in P52224. These proteins contain a predicted transmembrane helix. No signal peptide. 1 TMHs; Conserved hypothetical protein; heme exporter protein D	complement(4310410..4310631)	Azoarcus sp. BH72	4608448
YP_935435.1	CDS	ccmC	NC_008702.1	4310631	4311407	R	Probable heme exporter protein C (Cytochrome c-type biogenesis protein ccmC). Homology to ccmC of E. coli of 43% (sprot|CCMC_ECOLI). Required for the export of heme to the periplasm for the biogenesis of C-type cytochromes. Pfam: Cytrochrome C assembly protein no signal peptide probable 6 TMHs; High confidence in function and specificity; heme exporter protein C	complement(4310631..4311407)	Azoarcus sp. BH72	4608447
YP_935436.1	CDS	azo3934	NC_008702.1	4311404	4311499	R	Hypothetical protein predicted by Glimmer/Critica no homology to the data bank no domains predicted no signal peptide no TMHs; hypothetical protein	complement(4311404..4311499)	Azoarcus sp. BH72	4608446
YP_935437.1	CDS	ccmB	NC_008702.1	4311496	4312164	R	Probable heme exporter protein B (Cytochrome c-type biogenesis protein ccmB). Homology to ccmB (sprot|CCMB_ECOLI) of E. coli of 49%. Required for the export of heme to the periplasm for the biogenesis of C-type cytochromes (By similarity). no signal peptide probable 6 TMHs; High confidence in function and specificity; heme exporter protein B	complement(4311496..4312164)	Azoarcus sp. BH72	4608201
YP_935438.1	CDS	ccmA	NC_008702.1	4312158	4312784	R	ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA	complement(4312158..4312784)	Azoarcus sp. BH72	4608445
YP_935439.1	CDS	azo3937	NC_008702.1	4313372	4315009	D	Putative aerotaxis receptor, sensory_box TMHMM reporting 2 transmembrane helices. HTH reporting nucleic acid binding motif. Aerotaxis receptor. SIGNAL TRANSDUCER FOR AEROTAXIS. THE AEROTACTIC RESPONSES IS THE ACCUMULATION OF CELLS AROUND AIR BUBBLES. THE NATURE OF THE SENSORY STIMULUS DETECTED BY THIS PROTEIN IS THE PROTON MOTIVE FORCE OR CELLULAR REDOX STATE. IT USES A FAD PROSTHETIC GROUP AS A REDOX SENSOR TO MONITOR OXYGEN LEVELS.; Specificity unclear; putative aerotaxis receptor	4313372..4315009	Azoarcus sp. BH72	4608444
YP_935440.1	CDS	napC2	NC_008702.1	4315202	4315840	R	Probable cytochrome c-type protein NapC. Homology to napC of R. sphaeroides of 57% (sprot|NAPC_RHOSH). MEDIATES ELECTRON FLOW FROM QUINONES TO THE NAPAB COMPLEX. no signal peptide probable 1 TMHs; High confidence in function and specificity; cytochrome c-type protein NapC	complement(4315202..4315840)	Azoarcus sp. BH72	4608202
YP_935441.1	CDS	napB2	NC_008702.1	4315856	4316308	R	Probable diheme cytochrome c. Homology to napB of A. eutrophus of 47% (sprot|NAPB_ALCEU). SMALL SUBUNIT OF THE PERIPLASMIC NITRATE REDUCTASE (NAP). ONLY EXPRESSED AT HIGH LEVELS DURING AEROBIC GROWTH. NAPAB COMPLEX RECEIVES ELECTRONS FROM THE MEMBRANE-ANCHORED TETRAHEME NAPC PROTEIN THUS ALLOWING ELECTRON FLOW BETWEEN MEMBRANE AND PERIPLASM. ESSENTIAL FUNCTION FOR NITRATE ASSIMILATION AND MAY HAVE A ROLE IN ANAEROBIC METABOLISM. signal peptide no TMHs; High confidence in function and specificity; diheme cytochrome c	complement(4315856..4316308)	Azoarcus sp. BH72	4609333
YP_935442.1	CDS	napH	NC_008702.1	4316305	4317300	R	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane protein	complement(4316305..4317300)	Azoarcus sp. BH72	4609331
YP_935443.1	CDS	napG	NC_008702.1	4317297	4318157	R	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic protein	complement(4317297..4318157)	Azoarcus sp. BH72	4609339
YP_935444.1	CDS	napA2	NC_008702.1	4318452	4320995	R	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit	complement(4318452..4320995)	Azoarcus sp. BH72	4609338
YP_935445.1	CDS	napD2	NC_008702.1	4320997	4321251	R	Probable NapD protein, 38% Identity to TrEMBL;Q6LTW0, Has PF03927, NapD protein;IPR005623;Uncharacterized protein involved in formation of periplasmic nitrate reductase.; Family membership; periplasmic nitrate reductase subunit NapD	complement(4320997..4321251)	Azoarcus sp. BH72	4609329
YP_935446.1	CDS	napF	NC_008702.1	4321248	4321751	R	Probabel ferredoxin-type protein napF. Homology to napF of E. coli of 43% (sprot|NAPF_ECOLI). Involved in electron transfer ina a wide variety of metabolic reactions. InterPro: Ferredoxin-type protein NapF (IPR004496); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Tigrfam: napF: ferredoxin-type protein NapF Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity; ferredoxin-type protein NapF	complement(4321248..4321751)	Azoarcus sp. BH72	4609335
YP_935447.1	CDS	azo3945	NC_008702.1	4321945	4325139	R	Putative hybrid sensor and regulator protein,; Specificity unclear; putative hybrid sensor and regulator protein	complement(4321945..4325139)	Azoarcus sp. BH72	4609337
YP_935448.1	CDS	azo3946	NC_008702.1	4325235	4325588	D	Putative transcriptional regulator,; Function unclear; putative two component transcriptional regulator	4325235..4325588	Azoarcus sp. BH72	4608203
YP_935449.1	CDS	azo3947	NC_008702.1	4325551	4328109	R	Putative two component sensor protein,; Function unclear; putative two component sensor protein	complement(4325551..4328109)	Azoarcus sp. BH72	4608204
YP_935450.1	CDS	azo3948	NC_008702.1	4328357	4329781	R	Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity).; Specificity unclear; putative DNA-directed polymerase III	complement(4328357..4329781)	Azoarcus sp. BH72	4608205
YP_935451.1	CDS	ubiE2	NC_008702.1	4329784	4330548	R	Ubiquinone/menaquinone biosynthesis methyltransferase ubiE (EC 2.1.1.-). Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). InterPro: ubiE/COQ5 methyltransferase rrmJ: ribosomal RNA large subunit methy; High confidence in function and specificity; ubiquinone/menaquinone biosynthesis methyltransferase	complement(4329784..4330548)	Azoarcus sp. BH72	4608206
YP_935452.1	CDS	azo3950	NC_008702.1	4330672	4330863	R	Conserved hypothetical protein. Homology to RS02765 of R.solanacearum of 43% (trembl:Q8XWT5). No domains predicted. No TMHs. No signal peptide.; hypothetical protein	complement(4330672..4330863)	Azoarcus sp. BH72	4610059
YP_935453.1	CDS	spoT	NC_008702.1	4330962	4333160	R	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase,; High confidence in function and specificity; guanosine-3',5'-bis(diphosphate) 3'-diphosphatase	complement(4330962..4333160)	Azoarcus sp. BH72	4608207
YP_935454.1	CDS	rpoZ	NC_008702.1	4333183	4333398	R	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega	complement(4333183..4333398)	Azoarcus sp. BH72	4609889
YP_935455.1	CDS	gmk	NC_008702.1	4333401	4334015	R	Essential for recycling GMP and indirectly, cGMP; guanylate kinase	complement(4333401..4334015)	Azoarcus sp. BH72	4609804
YP_935456.1	CDS	azo3954	NC_008702.1	4334206	4334748	R	Similar to TREMBL:Q9HXG0 (60% identity); TREMBL:Q7NRZ4 (45% identity); TREMBL:Q88GB8 (43% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family.; Specificity unclear; isochorismatase family protein	complement(4334206..4334748)	Azoarcus sp. BH72	4608928
YP_935457.1	CDS	azo3955	NC_008702.1	4335032	4335799	D	Conserved hypothetical protein. Homology to Daro03000439 of Dechloromonas aromatica of 48% (gi|41725494|ref|ZP_00152252.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.; hypothetical protein	4335032..4335799	Azoarcus sp. BH72	4608208
YP_935458.1	CDS	azo3956	NC_008702.1	4335858	4337279	D	Conserved hypothetical protein, has weak homlogs in the Database. TrEMBL;Q88I83(25% Identity). gi|46140644|ref|ZP_00152253.2| , 30% Identity to Dechloromonas aromatica RCB,Nucleotidyltransferase/DNA polymerase involved in DNA repair Has PF00817,impB/mucB/samB family; IPR001126, UMUC_like; These proteins are involved in UV protection.In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. This machinery allows the replication to continue through DNA lesion, and therefore avoid lethal interruption of DNA replication after DNA damage. The UmuC is a well conserved protein in prokaryotes, with a homologue in yeast.; hypothetical protein	4335858..4337279	Azoarcus sp. BH72	4608209
YP_935459.1	CDS	azo3957	NC_008702.1	4337288	4340482	D	Region start changed from 4336170 to 4337262 (-1092 bases); DNA polymerase III subunit alpha	4337288..4340482	Azoarcus sp. BH72	4608210
YP_935460.1	CDS	pcaC	NC_008702.1	4340498	4340884	R	Carboxymuconolactone decarboxylase family protein,65% Identity (78% similarity) to TrEMBL;Q8EKK9. Has PF02627, Carboxymuconolactone decarboxylase family; IPR003779, CMD: Carboxymuconolactone decarboxylase (CMD)is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins (e.g. O67982) CMD represents the C-terminal domain, Abhydrolase_1 represents the N-terminal domain.; High confidence in function and specificity; 4-carboxymuconolactone decarboxylase	complement(4340498..4340884)	Azoarcus sp. BH72	4608211
YP_935461.1	CDS	cadR	NC_008702.1	4340829	4341284	R	Putative MerR-family transcriptional regulator,; Family membership; MerR family transcriptional regulator	complement(4340829..4341284)	Azoarcus sp. BH72	4609504
YP_935462.1	CDS	yicC	NC_008702.1	4341451	4342317	R	Putative alpha helix protein,yicC.42% identity(57% Similarity) to SwissProt;P23839, TrEMBL;Q8XD97(42%). TrEMBL; Q8XXF8(45% identity). Coils2 program reports the presence of Coiled-Coil. Has PF03755, YicC-like family, N-terminal region; IPR005229, Cons_hypoth255: Family of bacterial proteins. Although poorly characterised, the members of this protein family have been demonstrated to play a role in stationary phase survival. These proteins are not essential during stationary phase.; Conserved hypothetical protein; hypothetical protein	complement(4341451..4342317)	Azoarcus sp. BH72	4608409
YP_935463.1	CDS	azo3961	NC_008702.1	4342320	4343360	D	Putative serine/threonine protein kinase,; Family membership; putative serine/threonine protein kinase	4342320..4343360	Azoarcus sp. BH72	4610184
YP_935464.1	CDS	azo3962	NC_008702.1	4343372	4344292	D	Putative phosphoprotein phosphatase,; Conserved hypothetical protein; putative phosphoprotein phosphatase	4343372..4344292	Azoarcus sp. BH72	4608212
YP_935465.1	CDS	rph	NC_008702.1	4344315	4345034	D	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH	4344315..4345034	Azoarcus sp. BH72	4608213
YP_935466.1	CDS	azo3964	NC_008702.1	4345038	4345634	D	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase	4345038..4345634	Azoarcus sp. BH72	4609760
YP_935467.1	CDS	azo3965	NC_008702.1	4345631	4346854	D	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase	4345631..4346854	Azoarcus sp. BH72	4608214
YP_935468.1	CDS	azo3966	NC_008702.1	4346862	4347371	R	Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. No TMHs; hypothetical protein	complement(4346862..4347371)	Azoarcus sp. BH72	4608215
YP_935469.1	CDS	azo3967	NC_008702.1	4347471	4349312	R	Putative protease IV. homology to sspA of E. coli of 38% (sprot|SPPA_ECOLI). Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane. InterPro: Signal peptide peptidase SppA 67K type (IPR004634); Signal peptide peptidase SppA 36K type (IPR004635); Pepditase family U7 (IPR002142) Pfam: Peptidase family U7 Tigrfam: SppA_67K: signal peptide peptidase SppA; sppA_dom: signal peptide peptidase SppA no signal peptide probable 1 TMH; High confidence in function and specificity; putative protease IV	complement(4347471..4349312)	Azoarcus sp. BH72	4608216
YP_935470.1	CDS	trmB	NC_008702.1	4349397	4350149	R	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase	complement(4349397..4350149)	Azoarcus sp. BH72	4608217
YP_935471.1	CDS	thiG	NC_008702.1	4350146	4350931	R	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase	complement(4350146..4350931)	Azoarcus sp. BH72	4608218
YP_935472.1	CDS	thiS	NC_008702.1	4350986	4351189	R	Putative sulfur transfer protein involved in thimanin biosynsthesis.; High confidence in function and specificity; thiamine biosynthesis protein ThiS	complement(4350986..4351189)	Azoarcus sp. BH72	4608219
YP_935473.1	CDS	metX	NC_008702.1	4351391	4352518	D	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase	4351391..4352518	Azoarcus sp. BH72	4609939
YP_935474.1	CDS	metW	NC_008702.1	4352521	4353108	D	Q8YDE4:20% identity, 37% similarity. Ubiquinone/menaquinone biosynthesis methyltransferase ubiE . Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-14-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-14-benzoquinol (DMQH2) (By similarity). METHIONINE BIOSYNTHESIS PROTEIN Pfam:PPTA(protein prenyl transferase alpha subunit), FERM domain TIGRFAM:rmJ: ribosomal RNA large subunit methylation InterPro IPR000051; SAM_bind. IPR004034; Ubi/men_Metransf. IPR004033; UbiE/COQ5_Metrf. HTH predicted nucleic acid binding motif PROSITE PS01183; UBIE_1; 1. PS01184; UBIE_2; FALSE_NEG.; Family membership; putative methionine biosynthesis protein	4352521..4353108	Azoarcus sp. BH72	4609212
YP_935475.1	CDS	azo3973	NC_008702.1	4353124	4353927	R	Hypothetical protein. no homology of the entire protein to the data bank. Pfam: putative peptidoglycan binding domain. This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three alpha helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. no signal peptide. no TMHs; hypothetical protein	complement(4353124..4353927)	Azoarcus sp. BH72	4609211
YP_935476.1	CDS	azo3974	NC_008702.1	4354102	4354419	R	Conserved hypothetical protein. Homology to bb4936 of B. bronchiseptica of 36% (trembl|Q7WDQ2). no domains predicted. no signal peptide. no TMHs; hypothetical protein	complement(4354102..4354419)	Azoarcus sp. BH72	4608220
YP_935477.1	CDS	ampG	NC_008702.1	4354671	4356191	D	AmpG protein. Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling.Belong to the BT1 family of proteins. Presence of DUF domains and signail peptide. 11 tranmembrane helices.36% identity and 50% similarity to E.coli AmpG protein.(JW0423) 2A0125: AmpG-related permease; Family membership; putative AmpG protein	4354671..4356191	Azoarcus sp. BH72	4608221
YP_935478.1	CDS	azo3976	NC_008702.1	4356228	4356950	D	Probable uracil-DNA glycosylase. Has PF03167,Uracil DNA glycosylase superfamily;IPR005122 UDNA_glycsylseSF; Uracil-DNA glycosylase is a DNA repair enzyme that excises uracil residues from DNA by cleaving the N-glycosylic bond. Uracil in DNA can arise as a result of misincorportation of dUMP residues by DNA polymerase or deamination of cytosine. The sequence of uracil-DNA glycosylase is extremely well conserved; uracil-DNA glycosylase	4356228..4356950	Azoarcus sp. BH72	4608314
YP_935479.1	CDS	azo3977	NC_008702.1	4357121	4357792	D	Region start changed from 4356747 to 4357095 (-348 bases); putative carbonic anhydrase	4357121..4357792	Azoarcus sp. BH72	4608222
YP_935480.1	CDS	priA	NC_008702.1	4358238	4360409	R	Primosomal protein N (Replication factor Y). Recognizes a specific hairpin sequence on phiX ssDNA. This structure is then recognized and bound by proteins priB and priC. Formation of the primosome proceeds with the subsequent actions of dnaB dnaC dnaT and primase. PriA then functions as a helicase within the primosome. InterPro: DEAD/DEAH box helicase; High confidence in function and specificity; primosomal protein N'	complement(4358238..4360409)	Azoarcus sp. BH72	4608223
YP_935481.1	CDS	hemE	NC_008702.1	4360801	4361877	R	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase	complement(4360801..4361877)	Azoarcus sp. BH72	4609626
YP_935482.1	CDS	trkH2	NC_008702.1	4361965	4363437	R	This proteins are involved in active potassium uptake utilising ATP in the process. TrkH a member of the family TRKH is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.Requires TrkE for transport activity. 38% Cat_transpt.IPR004772; K_transptTrk. Pfam:PF02386; TrkH; 1. TIGRFAMs:TIGR00933; 2a38; 1. TMHelix:10. Signal peptide present.; High confidence in function and specificity; putative potassium system uptake protein	complement(4361965..4363437)	Azoarcus sp. BH72	4608983
YP_935483.1	CDS	trkA	NC_008702.1	4363437	4364840	R	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein	complement(4363437..4364840)	Azoarcus sp. BH72	4609972
YP_935484.1	CDS	ntrX	NC_008702.1	4364923	4366170	R	Probable nitrogen assimilation regulatory protein,; High confidence in function and specificity; nitrogen assimilation regulatory protein	complement(4364923..4366170)	Azoarcus sp. BH72	4609970
YP_935485.1	CDS	ntrY	NC_008702.1	4366174	4368294	R	Probable nitrogen regulation protein,; High confidence in function and specificity; nitrogen regulation protein	complement(4366174..4368294)	Azoarcus sp. BH72	4609415
YP_935486.1	CDS	azo3984	NC_008702.1	4368291	4368995	R	Conserved hypothetical secreted protein. Homology to RS02253 of R.solanacearum of 32% (trembl|Q8Y3A4(SRS)). No domains predicted. No TMHs. Signal peptide present.; Conserved hypothetical protein; hypothetical protein	complement(4368291..4368995)	Azoarcus sp. BH72	4609416
YP_935487.1	CDS	azo3985	NC_008702.1	4368856	4370136	R	SUN protein; Conserved hypothetical protein; Sun protein	complement(4368856..4370136)	Azoarcus sp. BH72	4608224
YP_935488.1	CDS	speE2	NC_008702.1	4370229	4371083	R	Spermidine synthase counts to a group of polyamine biosynthetic enzymes involved in the fifth (last) step in the biosynthesis of spermidine from arginine and methionine which includes; spermidine synthase, spermine synthase and putrescine N-methyltransferase. Similar to sprot|SPEE_NITEU (39%) and to sprot|SPE1_PSEAE (34%). ProSite (PS50193): SAM (and some other nucleotide) binding motif Pfam (PF01564): Spermidine synthase TIGRFAM: speE,spermidine synthase; Specificity unclear; spermidine synthase	complement(4370229..4371083)	Azoarcus sp. BH72	4608225
YP_935489.1	CDS	azo3987	NC_008702.1	4371199	4371963	R	Conserved hypothetical membrane protein. TREMBL:Q88FZ3: 44% identity, 60% similarity InterPro:IPR002781; DUF81.This domain is found in integral membrane proteins of prokaryotes which are uncharacterized Pfam:PF01925; DUF81 Signal peptide present and presence of 6 transmembrane helices.; Conserved hypothetical protein; hypothetical protein	complement(4371199..4371963)	Azoarcus sp. BH72	4609888
YP_935490.1	CDS	trmE	NC_008702.1	4372023	4373381	R	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE	complement(4372023..4373381)	Azoarcus sp. BH72	4608226
YP_935491.1	CDS	azo3989	NC_008702.1	4373353	4374969	R	Inner membrane protein oxaA. Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex (by similariety). Pfam: 60 kd inner membran proetin TMHs: 3 Signal peptide: no; High confidence in function and specificity; hypothetical protein	complement(4373353..4374969)	Azoarcus sp. BH72	4609933
YP_935492.1	CDS	azo3990	NC_008702.1	4375023	4375232	R	Conserved hypothetical protein, 62% identical(76% similar) to SwissProt;Q7NPT7. Has PF01809, Domain of unknown function DUF37;IPR002696;This domain is found in short (70 amino acid) hypothetical proteins from various bacteria. The domain contains three conserved cysteine residues. Q44066 from Aeromonas hydrophila has been found to have hemolytic activity (unpublished).; hypothetical protein	complement(4375023..4375232)	Azoarcus sp. BH72	4608227
YP_935493.1	CDS	azo3991	NC_008702.1	4375229	4375591	R	Region start changed from 4375477 to 4375591 (114 bases); ribonuclease P	complement(4375229..4375591)	Azoarcus sp. BH72	4608228
YP_935494.1	CDS	rpmH	NC_008702.1	4375593	4375931	R	Putative Ribosomal protein L34. Has PF00468,Ribosomal protein L34;IPR000271, Ribosomal_L34;Ribosomes are the particles that catalyze mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites.; Function unclear; putative ribosomal protein L34	complement(4375593..4375931)	Azoarcus sp. BH72	4608229
azo_tRNA_0001	tRNA	tRNA-Arg	NC_008702.1	204448	204524	D	tRNA-Arg	204448..204524	Azoarcus sp. BH72	4606252
azo_tRNA_0002	tRNA	tRNA-Ile	NC_008702.1	206413	206489	D	tRNA-Ile	206413..206489	Azoarcus sp. BH72	4608230
azo_tRNA_0003	tRNA	tRNA-Ala	NC_008702.1	206517	206592	D	tRNA-Ala	206517..206592	Azoarcus sp. BH72	4609998
azo_tRNA_0004	tRNA	tRNA-Lys	NC_008702.1	438216	438288	R	tRNA-Lys	complement(438216..438288)	Azoarcus sp. BH72	4608476
azo_tRNA_0005	tRNA	tRNA-Lys	NC_008702.1	601691	601766	R	tRNA-Lys	complement(601691..601766)	Azoarcus sp. BH72	4606455
azo_tRNA_0006	tRNA	tRNA-Ile	NC_008702.1	772335	772411	D	tRNA-Ile	772335..772411	Azoarcus sp. BH72	4608236
azo_tRNA_0007	tRNA	tRNA-Ala	NC_008702.1	772439	772514	D	tRNA-Ala	772439..772514	Azoarcus sp. BH72	4609999
azo_tRNA_0008	tRNA	tRNA-Gln	NC_008702.1	807603	807679	R	tRNA-Gln	complement(807603..807679)	Azoarcus sp. BH72	4609637
azo_tRNA_0009	tRNA	tRNA-Met	NC_008702.1	832451	832527	R	tRNA-Met	complement(832451..832527)	Azoarcus sp. BH72	4606560
azo_tRNA_0010	tRNA	tRNA-Leu	NC_008702.1	973414	973498	D	tRNA-Leu	973414..973498	Azoarcus sp. BH72	4609689
azo_tRNA_0011	tRNA	tRNA-Leu	NC_008702.1	1005095	1005179	R	tRNA-Leu	complement(1005095..1005179)	Azoarcus sp. BH72	4609654
azo_tRNA_0012	tRNA	tRNA-Leu	NC_008702.1	1005353	1005437	R	tRNA-Leu	complement(1005353..1005437)	Azoarcus sp. BH72	4610003
azo_tRNA_0013	tRNA	tRNA-Phe	NC_008702.1	1052967	1053042	D	tRNA-Phe	1052967..1053042	Azoarcus sp. BH72	4609925
azo_tRNA_0014	tRNA	tRNA-Pro	NC_008702.1	1091451	1091527	D	tRNA-Pro	1091451..1091527	Azoarcus sp. BH72	4609095
azo_tRNA_0015	tRNA	tRNA-Ala	NC_008702.1	1104890	1104965	D	tRNA-Ala	1104890..1104965	Azoarcus sp. BH72	4608881
azo_tRNA_0016	tRNA	tRNA-Glu	NC_008702.1	1104986	1105061	D	tRNA-Glu	1104986..1105061	Azoarcus sp. BH72	4609976
azo_tRNA_0017	tRNA	tRNA-Asp	NC_008702.1	1105124	1105200	D	tRNA-Asp	1105124..1105200	Azoarcus sp. BH72	4609991
azo_tRNA_0018	tRNA	tRNA-Ala	NC_008702.1	1105287	1105362	D	tRNA-Ala	1105287..1105362	Azoarcus sp. BH72	4609987
azo_tRNA_0019	tRNA	tRNA-Glu	NC_008702.1	1105372	1105447	D	tRNA-Glu	1105372..1105447	Azoarcus sp. BH72	4609977
azo_tRNA_0020	tRNA	tRNA-Asp	NC_008702.1	1105508	1105584	D	tRNA-Asp	1105508..1105584	Azoarcus sp. BH72	4609992
azo_tRNA_0021	tRNA	tRNA-Val	NC_008702.1	1162391	1162467	D	tRNA-Val	1162391..1162467	Azoarcus sp. BH72	4606683
azo_tRNA_0022	tRNA	tRNA-Pro	NC_008702.1	1170058	1170134	D	tRNA-Pro	1170058..1170134	Azoarcus sp. BH72	4606685
azo_tRNA_0023	tRNA	tRNA-Ser	NC_008702.1	1184957	1185046	D	tRNA-Ser	1184957..1185046	Azoarcus sp. BH72	4606691
azo_tRNA_0024	tRNA	tRNA-Thr	NC_008702.1	1283196	1283271	D	tRNA-Thr	1283196..1283271	Azoarcus sp. BH72	4609621
azo_tRNA_0025	tRNA	tRNA-Ile	NC_008702.1	1393517	1393593	D	tRNA-Ile	1393517..1393593	Azoarcus sp. BH72	4608234
azo_tRNA_0026	tRNA	tRNA-Ala	NC_008702.1	1393621	1393696	D	tRNA-Ala	1393621..1393696	Azoarcus sp. BH72	4610000
azo_tRNA_0027	tRNA	tRNA-Ser	NC_008702.1	1445319	1445408	R	tRNA-Ser	complement(1445319..1445408)	Azoarcus sp. BH72	4608995
azo_tRNA_0028	tRNA	tRNA-Arg	NC_008702.1	1466272	1466348	R	tRNA-Arg	complement(1466272..1466348)	Azoarcus sp. BH72	4606828
azo_tRNA_0029	tRNA	tRNA-Ala	NC_008702.1	1508492	1508567	D	tRNA-Ala	1508492..1508567	Azoarcus sp. BH72	4606840
azo_tRNA_0030	tRNA	tRNA-Leu	NC_008702.1	1524791	1524875	D	tRNA-Leu	1524791..1524875	Azoarcus sp. BH72	4609862
azo_tRNA_0031	tRNA	tRNA-Asn	NC_008702.1	1771974	1772049	R	tRNA-Asn	complement(1771974..1772049)	Azoarcus sp. BH72	4606941
azo_tRNA_0032	tRNA	tRNA-Asn	NC_008702.1	1772115	1772190	R	tRNA-Asn	complement(1772115..1772190)	Azoarcus sp. BH72	4609985
azo_tRNA_0033	tRNA	tRNA-Gly	NC_008702.1	1809899	1809974	D	tRNA-Gly	1809899..1809974	Azoarcus sp. BH72	4609533
azo_tRNA_0034	tRNA	tRNA-Cys	NC_008702.1	1810049	1810122	D	tRNA-Cys	1810049..1810122	Azoarcus sp. BH72	4609993
azo_tRNA_0035	tRNA	tRNA-Gly	NC_008702.1	1810132	1810207	D	tRNA-Gly	1810132..1810207	Azoarcus sp. BH72	4609989
azo_tRNA_0036	tRNA	tRNA-Leu	NC_008702.1	1812221	1812305	R	tRNA-Leu	complement(1812221..1812305)	Azoarcus sp. BH72	4606955
azo_tRNA_0037	tRNA	tRNA-Leu	NC_008702.1	2045941	2046025	D	tRNA-Leu	2045941..2046025	Azoarcus sp. BH72	4609732
azo_tRNA_0038	tRNA	tRNA-Val	NC_008702.1	2269150	2269224	R	tRNA-Val	complement(2269150..2269224)	Azoarcus sp. BH72	4607212
azo_tRNA_0039	tRNA	tRNA-Val	NC_008702.1	2269263	2269337	R	tRNA-Val	complement(2269263..2269337)	Azoarcus sp. BH72	4610026
azo_tRNA_0040	tRNA	tRNA-Val	NC_008702.1	2269418	2269493	R	tRNA-Val	complement(2269418..2269493)	Azoarcus sp. BH72	4610027
azo_tRNA_0041	tRNA	tRNA-His	NC_008702.1	2307999	2308074	R	tRNA-His	complement(2307999..2308074)	Azoarcus sp. BH72	4607227
azo_tRNA_0042	tRNA	tRNA-Arg	NC_008702.1	2308120	2308196	R	tRNA-Arg	complement(2308120..2308196)	Azoarcus sp. BH72	4609997
azo_tRNA_0043	tRNA	tRNA-Pro	NC_008702.1	2308224	2308300	R	tRNA-Pro	complement(2308224..2308300)	Azoarcus sp. BH72	4609983
azo_tRNA_0044	tRNA	tRNA-Ser	NC_008702.1	2508773	2508863	R	tRNA-Ser	complement(2508773..2508863)	Azoarcus sp. BH72	4607334
azo_tRNA_0045	tRNA	tRNA-Met	NC_008702.1	2869372	2869448	R	tRNA-Met	complement(2869372..2869448)	Azoarcus sp. BH72	4610060
azo_tRNA_0046	tRNA	tRNA-Thr	NC_008702.1	2962600	2962675	R	tRNA-Thr	complement(2962600..2962675)	Azoarcus sp. BH72	4607572
azo_tRNA_0047	tRNA	tRNA-Ser	NC_008702.1	3423041	3423134	R	tRNA-Ser	complement(3423041..3423134)	Azoarcus sp. BH72	4607796
azo_tRNA_0048	tRNA	tRNA-Arg	NC_008702.1	3499971	3500045	D	tRNA-Arg	3499971..3500045	Azoarcus sp. BH72	4607838
azo_tRNA_0049	tRNA	tRNA-Ala	NC_008702.1	3515151	3515226	R	tRNA-Ala	complement(3515151..3515226)	Azoarcus sp. BH72	4608233
azo_tRNA_0050	tRNA	tRNA-Ile	NC_008702.1	3515254	3515330	R	tRNA-Ile	complement(3515254..3515330)	Azoarcus sp. BH72	4609980
azo_tRNA_0051	tRNA	azo_tRNA_0051	NC_008702.1	3559218	3559501	D	tRNA-Ile	join(3559218..3559256,3559462..3559501)	Azoarcus sp. BH72	4609797
azo_tRNA_0052	tRNA	tRNA-Trp	NC_008702.1	3759284	3759359	R	tRNA-Trp	complement(3759284..3759359)	Azoarcus sp. BH72	4609860
azo_tRNA_0053	tRNA	tRNA-Thr	NC_008702.1	3760686	3760760	R	tRNA-Thr	complement(3760686..3760760)	Azoarcus sp. BH72	4610049
azo_tRNA_0054	tRNA	tRNA-Gly	NC_008702.1	3760782	3760855	R	tRNA-Gly	complement(3760782..3760855)	Azoarcus sp. BH72	4610022
azo_tRNA_0055	tRNA	tRNA-Tyr	NC_008702.1	3760941	3761025	R	tRNA-Tyr	complement(3760941..3761025)	Azoarcus sp. BH72	4609995
azo_tRNA_0056	tRNA	tRNA-Gly	NC_008702.1	4144876	4144950	D	tRNA-Gly	4144876..4144950	Azoarcus sp. BH72	4609649
azo_rrn1	rRNA	azo_rrn1	NC_008702.1	204806	206339	D	16S ribosomal RNA	204806..206339	Azoarcus sp. BH72	4609981
azo_rrn2	rRNA	azo_rrn2	NC_008702.1	206857	209743	D	23S ribosomal RNA	206857..209743	Azoarcus sp. BH72	4609974
azo_rrn2a	rRNA	azo_rrn2a	NC_008702.1	209845	209962	D	5S ribosomal RNA	209845..209962	Azoarcus sp. BH72	5309637
azo_rrn7	rRNA	azo_rrn7	NC_008702.1	770728	772261	D	16S ribosomal RNA	770728..772261	Azoarcus sp. BH72	4608631
azo_rrn8	rRNA	azo_rrn8	NC_008702.1	772779	775665	D	23S ribosomal RNA	772779..775665	Azoarcus sp. BH72	4609975
azo_rrn8a	rRNA	azo_rrn8a	NC_008702.1	775767	775884	D	5S ribosomal RNA	775767..775884	Azoarcus sp. BH72	5309636
azo_rrn5	rRNA	azo_rrn5	NC_008702.1	1391911	1393444	D	16S ribosomal RNA	1391911..1393444	Azoarcus sp. BH72	4608872
azo_rrn6	rRNA	azo_rrn6	NC_008702.1	1393962	1396848	D	23S ribosomal RNA	1393962..1396848	Azoarcus sp. BH72	4609978
azo_rrn6a	rRNA	azo_rrn6a	NC_008702.1	1396949	1397066	D	5S ribosomal RNA	1396949..1397066	Azoarcus sp. BH72	5309635
azo3194a	rRNA	azo3194a	NC_008702.1	3511781	3511898	R	5S ribosomal RNA	complement(3511781..3511898)	Azoarcus sp. BH72	5309634
azo_rrn4	rRNA	azo_rrn4	NC_008702.1	3511974	3514860	R	23S ribosomal RNA	complement(3511974..3514860)	Azoarcus sp. BH72	4607845
azo_rrn3	rRNA	azo_rrn3	NC_008702.1	3515378	3516911	R	16S ribosomal RNA	complement(3515378..3516911)	Azoarcus sp. BH72	4610001