-- dump date 20140618_214226 -- class Genbank::CDS -- table cds_note -- id note YP_002443542.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002443543.1 identified by match to protein family HMM PF00583 YP_002443546.1 identified by match to protein family HMM PF07883 YP_002443547.1 identified by match to protein family HMM PF07883 YP_002443549.1 identified by match to protein family HMM PF00011; match to protein family HMM PF04969 YP_002443550.1 identified by glimmer; putative YP_002443552.1 identified by match to protein family HMM PF01076 YP_002449041.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002449042.1 binds the polymerase to DNA and acts as a sliding clamp YP_002449043.1 identified by match to protein family HMM TIGR02988 YP_002449044.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002449045.1 negatively supercoils closed circular double-stranded DNA YP_002449046.1 negatively supercoils closed circular double-stranded DNA YP_002449048.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002449049.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002449050.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_002449051.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_002449052.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002449053.1 identified by glimmer; putative YP_002449054.1 identified by match to protein family HMM PF01712 YP_002449055.1 identified by match to protein family HMM PF01712 YP_002449056.1 identified by match to protein family HMM PF00857 YP_002449057.1 identified by match to protein family HMM PF00383 YP_002449058.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002449059.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002449060.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002449062.1 identified by match to protein family HMM PF07441; match to protein family HMM TIGR02862 YP_002449064.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002449065.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002449066.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002449067.1 identified by match to protein family HMM PF04468 YP_002449068.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_002449070.1 identified by match to protein family HMM PF01541 YP_002449071.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002449072.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002449073.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002449074.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002449075.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334 YP_002449076.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002449077.1 identified by match to protein family HMM PF05582; match to protein family HMM TIGR02855 YP_002449078.1 identified by match to protein family HMM PF06257 YP_002449080.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002449081.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743 YP_002449082.1 identified by glimmer; putative YP_002449083.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002449084.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus YP_002449085.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002449086.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002449087.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002449089.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002449090.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851 YP_002449091.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002449092.1 identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444 YP_002449093.1 identified by match to protein family HMM PF01479 YP_002449094.1 identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892 YP_002449095.1 identified by match to protein family HMM PF09578; match to protein family HMM TIGR02893 YP_002449096.1 identified by match to protein family HMM PF04977 YP_002449097.1 identified by match to protein family HMM PF00575 YP_002449098.1 identified by match to protein family HMM PF07228; match to protein family HMM TIGR02865 YP_002449099.1 identified by match to protein family HMM PF01171; match to protein family HMM PF06508; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433 YP_002449100.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002449101.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241 YP_002449102.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_002449103.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002449104.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002449105.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715 YP_002449106.1 amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis YP_002449107.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002449108.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002449109.1 identified by match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526 YP_002449110.1 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498 YP_002449111.1 identified by match to protein family HMM PF01381 YP_002449112.1 identified by match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002449113.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002449114.1 identified by match to protein family HMM PF05848 YP_002449115.1 identified by match to protein family HMM PF02151 YP_002449116.1 identified by match to protein family HMM PF00217 YP_002449117.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002449118.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002449119.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair YP_002449120.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002449121.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01938 YP_002449122.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002449123.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002449124.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002449125.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172 YP_002449126.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002449127.1 identified by match to protein family HMM PF00636 YP_002449128.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186 YP_002449129.1 identified by match to protein family HMM PF05991 YP_002449130.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002449131.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002449132.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02357 YP_002449133.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002449134.1 binds directly to 23S ribosomal RNA YP_002449135.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002449136.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002449137.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002449138.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_002449139.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449140.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002449141.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002449142.1 identified by match to protein family HMM PF01248 YP_002449143.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002449144.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002449145.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002449146.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002449147.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002449148.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002449149.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002449150.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002449151.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002449152.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002449153.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002449154.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002449155.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002449156.1 one of the stabilizing components for the large ribosomal subunit YP_002449157.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002449158.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002449159.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002449160.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002449161.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_002449162.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002449163.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002449164.1 binds 5S rRNA along with protein L5 and L25 YP_002449165.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002449166.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002449167.1 late assembly protein YP_002449168.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00344; match to protein family HMM TIGR00967 YP_002449169.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002449170.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002449171.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002449172.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002449173.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002449174.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002449175.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002449176.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002449177.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002449178.1 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_002449179.1 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_002449180.1 identified by match to protein family HMM PF02361 YP_002449181.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002449182.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002449183.1 forms a direct contact with the tRNA during translation YP_002449185.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR02883 YP_002449186.1 identified by match to protein family HMM PF01883 YP_002449189.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02764 YP_002449191.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002449192.1 identified by match to protein family HMM PF00491; match to protein family HMM TIGR01229 YP_002449193.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159 YP_002449194.1 identified by match to protein family HMM PF07949 YP_002449195.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002449196.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002449197.1 identified by match to protein family HMM PF00561 YP_002449198.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002449199.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01314 YP_002449200.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002449201.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002449202.1 identified by match to protein family HMM PF00326; match to protein family HMM PF07676 YP_002449204.1 identified by match to protein family HMM PF04173; match to protein family HMM PF07681 YP_002449206.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002449208.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002449209.1 identified by match to protein family HMM PF00528 YP_002449210.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002449211.1 identified by match to protein family HMM PF03180 YP_002449212.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002449214.1 identified by match to protein family HMM PF01565 YP_002449217.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_002449219.1 identified by glimmer; putative YP_002449220.1 identified by match to protein family HMM PF00528 YP_002449221.1 identified by match to protein family HMM PF00528 YP_002449222.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449223.1 identified by match to protein family HMM PF00005 YP_002449224.1 identified by match to protein family HMM PF00496 YP_002449226.1 identified by match to protein family HMM PF00165 YP_002449229.1 identified by match to protein family HMM PF00496 YP_002449230.1 identified by match to protein family HMM PF00496 YP_002449231.1 identified by match to protein family HMM PF00248 YP_002449232.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002449233.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002449234.1 identified by match to protein family HMM PF06800 YP_002449235.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02141 YP_002449236.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256 YP_002449237.1 identified by match to protein family HMM PF05930; match to protein family HMM TIGR01764 YP_002449238.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002449239.1 identified by match to protein family HMM PF00892 YP_002449240.1 identified by glimmer; putative YP_002449241.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002449242.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002449243.1 identified by match to protein family HMM PF02588 YP_002449244.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002449245.1 identified by glimmer; putative YP_002449246.1 identified by match to protein family HMM PF01026 YP_002449248.1 identified by match to protein family HMM PF01464 YP_002449252.1 identified by glimmer; putative YP_002449253.1 identified by match to protein family HMM PF00005 YP_002449254.1 identified by glimmer; putative YP_002449255.1 identified by glimmer; putative YP_002449256.1 identified by match to protein family HMM PF00496 YP_002449257.1 identified by match to protein family HMM PF00528 YP_002449258.1 identified by match to protein family HMM PF00528 YP_002449259.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449260.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449261.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002449263.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449264.1 identified by glimmer; putative YP_002449266.1 identified by glimmer; putative YP_002449267.1 identified by glimmer; putative YP_002449268.1 identified by match to protein family HMM PF00903; match to protein family HMM TIGR01263 YP_002449269.1 identified by match to protein family HMM PF01557 YP_002449270.1 identified by match to protein family HMM PF04209 YP_002449271.1 identified by match to protein family HMM PF07690 YP_002449272.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002449273.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002449274.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002449275.1 identified by match to protein family HMM PF03851; match to protein family HMM TIGR00629 YP_002449276.1 identified by match to protein family HMM PF01694 YP_002449277.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002449279.1 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492 YP_002449281.1 identified by match to protein family HMM PF02452 YP_002449282.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371 YP_002449283.1 identified by match to protein family HMM PF03926 YP_002449284.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150 YP_002449285.1 identified by match to protein family HMM PF00814 YP_002449286.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002449287.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002449288.1 identified by match to protein family HMM PF00005 YP_002449289.1 modulates transcription in response to the NADH/NAD(+) redox state YP_002449291.1 identified by match to protein family HMM PF02517 YP_002449292.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002449293.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002449294.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002449295.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002449296.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449297.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002449299.1 identified by match to protein family HMM PF01323 YP_002449301.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002449303.1 identified by glimmer; putative YP_002449304.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002449305.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002449306.1 identified by match to protein family HMM PF00534; match to protein family HMM PF00535 YP_002449307.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002449309.1 identified by match to protein family HMM PF00005 YP_002449310.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002449311.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449312.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002449313.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002449314.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002449315.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002449316.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_002449317.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002449318.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002449319.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002449320.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002449321.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002449322.1 involved in de novo purine biosynthesis YP_002449323.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002449325.1 identified by match to protein family HMM PF01145 YP_002449327.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer YP_002449328.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073 YP_002449329.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002449330.1 identified by match to protein family HMM PF07537 YP_002449331.1 identified by match to protein family HMM PF01925 YP_002449332.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_002449334.1 identified by match to protein family HMM PF00857 YP_002449335.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002449336.1 identified by match to protein family HMM PF00528 YP_002449337.1 identified by match to protein family HMM PF03180 YP_002449338.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01527 YP_002449339.1 identified by match to protein family HMM PF00665 YP_002449340.1 identified by glimmer; putative YP_002449341.1 identified by match to protein family HMM PF02374; match to protein family HMM TIGR00345 YP_002449342.1 identified by match to protein family HMM PF01047 YP_002449343.1 identified by match to protein family HMM PF05360 YP_002449344.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_002449345.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002449346.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002449347.1 similar to YegS from E. coli YP_002449348.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002449349.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002449350.1 identified by match to protein family HMM PF00158; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002449351.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01780 YP_002449352.1 identified by match to protein family HMM PF00893 YP_002449353.1 identified by match to protein family HMM PF02073 YP_002449354.1 identified by match to protein family HMM PF01522 YP_002449355.1 identified by match to protein family HMM PF01522 YP_002449356.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002449357.1 identified by match to protein family HMM PF01938; match to protein family HMM PF02475; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002449358.1 identified by match to protein family HMM PF01207 YP_002449359.1 identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002449360.1 identified by match to protein family HMM PF07308 YP_002449361.1 identified by match to protein family HMM PF01863 YP_002449363.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002449365.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002449366.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002449368.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_002449369.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR03137 YP_002449370.1 related protein from Bacillus subtilis functions as methylribose kinase and functions in salvage pathway YP_002449371.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_002449372.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002449373.1 identified by match to protein family HMM PF01032 YP_002449374.1 identified by match to protein family HMM PF01032 YP_002449375.1 identified by match to protein family HMM PF01497 YP_002449376.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002449377.1 identified by glimmer; putative YP_002449378.1 identified by match to protein family HMM TIGR01764 YP_002449382.1 identified by glimmer; putative YP_002449383.1 identified by glimmer; putative YP_002449384.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449385.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002449386.1 identified by glimmer; putative YP_002449387.1 identified by match to protein family HMM PF04199 YP_002449390.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002449391.1 identified by match to protein family HMM PF00355; match to protein family HMM PF01266 YP_002449392.1 identified by match to protein family HMM PF00487 YP_002449393.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002449394.1 identified by match to protein family HMM PF00497 YP_002449395.1 identified by match to protein family HMM PF00005 YP_002449396.1 identified by glimmer; putative YP_002449397.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002449398.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529 YP_002449399.1 catalyzes the degradation of arginine to citruline and ammonia YP_002449400.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002449401.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002449402.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002449403.1 identified by match to protein family HMM PF00027 YP_002449405.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00128 YP_002449406.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02003 YP_002449407.1 identified by match to protein family HMM PF03372 YP_002449408.1 identified by glimmer; putative YP_002449409.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002449410.1 decatenates replicating daughter chromosomes YP_002449411.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002449412.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_002449413.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002449414.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002449415.1 identified by match to protein family HMM PF01910 YP_002449416.1 identified by match to protein family HMM PF00528 YP_002449417.1 identified by match to protein family HMM PF09084 YP_002449418.1 identified by match to protein family HMM PF00005 YP_002449419.1 identified by match to protein family HMM PF00005 YP_002449420.1 identified by match to protein family HMM PF00041; match to protein family HMM PF00553; match to protein family HMM PF00704 YP_002449421.1 identified by match to protein family HMM PF09350 YP_002449423.1 identified by glimmer; putative YP_002449425.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08360 YP_002449426.1 identified by match to protein family HMM PF07690 YP_002449427.1 identified by match to protein family HMM PF01381 YP_002449429.1 identified by match to protein family HMM PF07690 YP_002449430.1 identified by match to protein family HMM PF01663 YP_002449432.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002449433.1 identified by match to protein family HMM TIGR01167 YP_002449434.1 identified by match to protein family HMM PF00480 YP_002449435.1 identified by match to protein family HMM PF02342 YP_002449436.1 identified by match to protein family HMM PF02342 YP_002449437.1 identified by match to protein family HMM PF02342 YP_002449438.1 identified by match to protein family HMM PF03741 YP_002449440.1 identified by match to protein family HMM PF05816 YP_002449441.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002449442.1 identified by match to protein family HMM PF06569 YP_002449443.1 identified by match to protein family HMM PF01451 YP_002449445.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765 YP_002449446.1 identified by glimmer; putative YP_002449447.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525 YP_002449448.1 identified by match to protein family HMM PF00892 YP_002449449.1 identified by match to protein family HMM PF07947 YP_002449451.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002449452.1 identified by glimmer; putative YP_002449453.1 identified by match to protein family HMM PF09335 YP_002449454.1 identified by match to protein family HMM PF00892 YP_002449456.1 identified by match to protein family HMM PF01243 YP_002449457.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00378; match to protein family HMM TIGR00846 YP_002449459.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08756 YP_002449461.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002449462.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02884 YP_002449463.1 identified by match to protein family HMM PF00730 YP_002449464.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002449465.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002449466.1 identified by glimmer; putative YP_002449467.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_002449468.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06803 YP_002449469.1 identified by match to protein family HMM TIGR02840 YP_002449470.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002449472.1 catalyzes the formation of glutamate from glutamine YP_002449473.1 identified by glimmer; putative YP_002449474.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01998 YP_002449475.1 identified by match to protein family HMM PF00144 YP_002449476.1 identified by glimmer; putative YP_002449478.1 identified by match to protein family HMM PF00535 YP_002449479.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002449480.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002449481.1 identified by match to protein family HMM PF00535 YP_002449482.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002449483.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493 YP_002449484.1 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids YP_002449487.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002449488.1 identified by match to protein family HMM PF01370; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_002449489.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002449490.1 identified by match to protein family HMM PF08838 YP_002449491.1 identified by glimmer; putative YP_002449492.1 SASP K; found in the forespore compartment YP_002449494.1 identified by match to protein family HMM PF04307 YP_002449495.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002449497.1 identified by match to protein family HMM PF04259; match to protein family HMM TIGR01442 YP_002449498.1 identified by glimmer; putative YP_002449500.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01527 YP_002449501.1 identified by match to protein family HMM PF00665 YP_002449502.1 identified by match to protein family HMM PF04167 YP_002449503.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002449504.1 identified by match to protein family HMM PF06081 YP_002449505.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898 YP_002449506.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_002449507.1 identified by match to protein family HMM PF00005 YP_002449508.1 identified by match to protein family HMM PF06182 YP_002449509.1 identified by match to protein family HMM PF06182 YP_002449510.1 identified by match to protein family HMM PF07885 YP_002449511.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002449512.1 identified by match to protein family HMM PF01475 YP_002449515.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002449516.1 identified by match to protein family HMM PF00293 YP_002449517.1 identified by match to protein family HMM PF00912 YP_002449518.1 identified by match to protein family HMM PF01323 YP_002449519.1 identified by match to protein family HMM PF00037; match to protein family HMM PF03130; match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_002449521.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00185 YP_002449522.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002449523.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_002449524.1 identified by match to protein family HMM PF04285; match to protein family HMM TIGR02877 YP_002449525.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002449527.1 identified by match to protein family HMM PF06114 YP_002449528.1 identified by match to protein family HMM PF01381 YP_002449529.1 identified by match to protein family HMM PF01381 YP_002449531.1 identified by glimmer; putative YP_002449533.1 identified by glimmer; putative YP_002449534.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002449535.1 unwinds double stranded DNA YP_002449536.1 identified by glimmer; putative YP_002449537.1 identified by glimmer; putative YP_002449540.1 identified by match to protein family HMM PF00692; match to protein family HMM TIGR00576 YP_002449542.1 identified by glimmer; putative YP_002449543.1 identified by match to protein family HMM PF09643; match to protein family HMM TIGR01671 YP_002449544.1 identified by glimmer; putative YP_002449546.1 identified by glimmer; putative YP_002449547.1 identified by glimmer; putative YP_002449549.1 identified by match to protein family HMM TIGR01637 YP_002449550.1 identified by match to protein family HMM PF00589 YP_002449551.1 identified by glimmer; putative YP_002449554.1 identified by match to protein family HMM PF01844 YP_002449555.1 identified by glimmer; putative YP_002449557.1 identified by match to protein family HMM PF03354 YP_002449558.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002449559.1 identified by match to protein family HMM PF00574 YP_002449561.1 identified by glimmer; putative YP_002449563.1 identified by match to protein family HMM TIGR01563 YP_002449567.1 identified by glimmer; putative YP_002449568.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002449569.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002449570.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002449572.1 identified by match to protein family HMM TIGR01665 YP_002449576.1 identified by glimmer; putative YP_002449577.1 identified by match to protein family HMM PF01183 YP_002449579.1 identified by match to protein family HMM PF01726 YP_002449581.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05031; match to protein family HMM TIGR01167 YP_002449582.1 identified by match to protein family HMM PF00583 YP_002449583.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842 YP_002449584.1 identified by match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453 YP_002449585.1 identified by match to protein family HMM PF01957 YP_002449586.1 identified by match to protein family HMM PF01145 YP_002449587.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002449588.1 identified by match to protein family HMM PF02518 YP_002449589.1 identified by match to protein family HMM PF00072 YP_002449590.1 identified by match to protein family HMM PF03600; match to protein family HMM PF03606; match to protein family HMM PF06808; match to protein family HMM TIGR00784 YP_002449593.1 identified by match to protein family HMM PF00023 YP_002449594.1 identified by match to protein family HMM PF04309 YP_002449595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_002449596.1 identified by match to protein family HMM PF00528 YP_002449597.1 identified by match to protein family HMM PF00528 YP_002449598.1 identified by match to protein family HMM PF01547 YP_002449599.1 identified by match to protein family HMM PF00149 YP_002449600.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449601.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002449602.1 identified by glimmer; putative YP_002449604.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002449605.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002449606.1 identified by match to protein family HMM PF00072 YP_002449607.1 identified by match to protein family HMM PF03390 YP_002449608.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949 YP_002449610.1 identified by match to protein family HMM PF00892 YP_002449611.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002449612.1 identified by match to protein family HMM PF00583 YP_002449613.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002449614.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449616.1 identified by match to protein family HMM PF00583 YP_002449617.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002449618.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_002449619.1 identified by match to protein family HMM PF07849 YP_002449621.1 identified by match to protein family HMM PF03009 YP_002449622.1 identified by match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF05222; match to protein family HMM TIGR00518 YP_002449623.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002449624.1 identified by match to protein family HMM PF01022 YP_002449625.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525 YP_002449626.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002449627.1 identified by match to protein family HMM PF00515; match to protein family HMM PF01381 YP_002449629.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002449630.1 identified by match to protein family HMM PF09335 YP_002449632.1 identified by glimmer; putative YP_002449633.1 identified by match to protein family HMM PF04294 YP_002449634.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002449635.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002449636.1 identified by match to protein family HMM PF00903 YP_002449637.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002449638.1 catalyzes the formation of fumarate from aspartate YP_002449639.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002449640.1 identified by match to protein family HMM PF01022 YP_002449641.1 SASP H; spore coat; expressed in forespore compartment YP_002449642.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002449643.1 identified by match to protein family HMM PF01497 YP_002449644.1 identified by match to protein family HMM PF01032 YP_002449645.1 identified by match to protein family HMM PF01032 YP_002449646.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00005 YP_002449647.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002449648.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002449649.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993 YP_002449650.1 identified by match to protein family HMM PF00293 YP_002449652.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002449653.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002449654.1 identified by glimmer; putative YP_002449655.1 identified by glimmer; putative YP_002449656.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002449657.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03222 YP_002449658.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404 YP_002449659.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992 YP_002449660.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002449661.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449662.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449663.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002449664.1 identified by match to protein family HMM PF03323 YP_002449665.1 identified by match to protein family HMM PF02517 YP_002449666.1 identified by match to protein family HMM PF01636 YP_002449667.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002449668.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449669.1 identified by match to protein family HMM PF00005 YP_002449670.1 identified by match to protein family HMM PF00497 YP_002449671.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002449672.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002449673.1 identified by match to protein family HMM PF00324 YP_002449674.1 identified by match to protein family HMM PF02566 YP_002449675.1 identified by match to protein family HMM PF01230 YP_002449676.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002449678.1 identified by match to protein family HMM PF08279 YP_002449679.1 identified by match to protein family HMM PF01872 YP_002449680.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002449681.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449683.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002449684.1 identified by match to protein family HMM PF00582 YP_002449685.1 identified by glimmer; putative YP_002449686.1 identified by match to protein family HMM PF00496 YP_002449687.1 identified by match to protein family HMM PF00528 YP_002449688.1 identified by match to protein family HMM PF00528 YP_002449689.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002449690.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449691.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00712; match to protein family HMM TIGR00881 YP_002449692.1 identified by match to protein family HMM PF01047 YP_002449693.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002449694.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002449695.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152 YP_002449696.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002449697.1 identified by match to protein family HMM PF00005 YP_002449698.1 identified by match to protein family HMM PF02653 YP_002449699.1 identified by match to protein family HMM PF00532 YP_002449700.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_002449701.1 identified by match to protein family HMM PF05547; match to protein family HMM TIGR03296 YP_002449702.1 identified by match to protein family HMM PF07690 YP_002449703.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002449704.1 identified by match to protein family HMM PF07885 YP_002449705.1 identified by match to protein family HMM PF00882 YP_002449706.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR03395 YP_002449708.1 identified by match to protein family HMM PF01565; match to protein family HMM PF04030; match to protein family HMM TIGR01679 YP_002449709.1 identified by match to protein family HMM PF04892 YP_002449710.1 identified by glimmer; putative YP_002449711.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002449712.1 identified by match to protein family HMM PF00015 YP_002449713.1 identified by match to protein family HMM PF06725 YP_002449714.1 identified by match to protein family HMM PF01381 YP_002449716.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002449717.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002449718.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002449721.1 identified by match to protein family HMM PF00324 YP_002449722.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002449723.1 identified by match to protein family HMM PF01381 YP_002449724.1 identified by glimmer; putative YP_002449725.1 identified by match to protein family HMM PF00583 YP_002449726.1 identified by glimmer; putative YP_002449727.1 identified by match to protein family HMM PF00999; match to protein family HMM PF02080; match to protein family HMM PF02254 YP_002449728.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02901 YP_002449729.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02897 YP_002449730.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02882 YP_002449731.1 identified by match to protein family HMM PF02790; match to protein family HMM TIGR01432 YP_002449733.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002449735.1 identified by match to protein family HMM PF00474 YP_002449736.1 identified by match to protein family HMM PF03323 YP_002449737.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002449738.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002449739.1 identified by glimmer; putative YP_002449740.1 identified by match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670 YP_002449741.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231 YP_002449742.1 identified by match to protein family HMM PF04023 YP_002449743.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136 YP_002449744.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002449745.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002449747.1 identified by match to protein family HMM PF00873 YP_002449748.1 identified by glimmer; putative YP_002449749.1 identified by match to protein family HMM PF00571 YP_002449750.1 identified by glimmer; putative YP_002449751.1 identified by glimmer; putative YP_002449753.1 identified by match to protein family HMM PF01551; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002449754.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03070 YP_002449755.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00005 YP_002449756.1 identified by match to protein family HMM PF00528 YP_002449757.1 identified by match to protein family HMM PF09084 YP_002449758.1 regulates the production of extracellular enzymes YP_002449759.1 identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352 YP_002449760.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_002449761.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002449762.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002449763.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002449764.1 identified by glimmer; putative YP_002449765.1 identified by glimmer; putative YP_002449766.1 identified by glimmer; putative YP_002449767.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002449768.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002449769.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_002449770.1 identified by match to protein family HMM PF00582; match to protein family HMM PF02702 YP_002449771.1 identified by match to protein family HMM PF07690 YP_002449772.1 identified by match to protein family HMM PF01047 YP_002449773.1 identified by match to protein family HMM PF01734 YP_002449774.1 identified by glimmer; putative YP_002449775.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002449776.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00106 YP_002449777.1 identified by match to protein family HMM PF03734 YP_002449778.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449779.1 identified by match to protein family HMM PF07561 YP_002449780.1 identified by match to protein family HMM PF00085 YP_002449781.1 identified by match to protein family HMM PF02600 YP_002449784.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002449785.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002449786.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002449787.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03323 YP_002449789.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449790.1 identified by match to protein family HMM PF04293 YP_002449792.1 identified by glimmer; putative YP_002449793.1 identified by glimmer; putative YP_002449795.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities YP_002449796.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02384 YP_002449797.1 identified by match to protein family HMM PF01420 YP_002449799.1 identified by glimmer; putative YP_002449800.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002449801.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002449803.1 identified by match to protein family HMM PF01381 YP_002449805.1 identified by match to protein family HMM PF00239 YP_002449806.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002449808.1 identified by glimmer; putative YP_002449809.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF04293 YP_002449810.1 identified by match to protein family HMM PF08878 YP_002449811.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002449814.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002449815.1 identified by glimmer; putative YP_002449818.1 identified by match to protein family HMM PF00089 YP_002449819.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449820.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR03385 YP_002449821.1 identified by match to protein family HMM PF02583 YP_002449822.1 identified by match to protein family HMM PF00581; match to protein family HMM PF01206 YP_002449823.1 identified by match to protein family HMM PF00753 YP_002449824.1 identified by match to protein family HMM PF01206 YP_002449825.1 identified by match to protein family HMM PF00581 YP_002449826.1 identified by match to protein family HMM PF00581 YP_002449827.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002449828.1 identified by match to protein family HMM PF01925 YP_002449829.1 identified by glimmer; putative YP_002449830.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002449831.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_002449832.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704 YP_002449833.1 identified by match to protein family HMM PF07690 YP_002449834.1 identified by match to protein family HMM PF05913 YP_002449835.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002449836.1 identified by match to protein family HMM PF02255 YP_002449837.1 identified by match to protein family HMM PF02302 YP_002449838.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002449839.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02378 YP_002449840.1 identified by glimmer; putative YP_002449841.1 identified by match to protein family HMM PF05913 YP_002449842.1 identified by match to protein family HMM PF03130 YP_002449843.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002449844.1 identified by match to protein family HMM PF02687 YP_002449845.1 identified by match to protein family HMM PF00005 YP_002449846.1 identified by match to protein family HMM TIGR01730 YP_002449847.1 identified by match to protein family HMM PF09529; match to protein family HMM TIGR02206 YP_002449848.1 identified by match to protein family HMM PF00528 YP_002449849.1 identified by match to protein family HMM PF00528 YP_002449850.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002449851.1 identified by match to protein family HMM PF05067 YP_002449856.1 identified by match to protein family HMM PF02735; match to protein family HMM TIGR02772 YP_002449857.1 identified by match to protein family HMM PF06803 YP_002449858.1 identified by match to protein family HMM PF09335 YP_002449859.1 identified by glimmer; putative YP_002449860.1 identified by glimmer; putative YP_002449861.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002449862.1 identified by glimmer; putative YP_002449863.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00041; match to protein family HMM PF00149 YP_002449865.1 identified by glimmer; putative YP_002449866.1 identified by match to protein family HMM PF00324 YP_002449867.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00932 YP_002449868.1 identified by glimmer; putative YP_002449869.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002449870.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002449871.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378 YP_002449872.1 identified by match to protein family HMM PF05913 YP_002449873.1 identified by match to protein family HMM PF07681 YP_002449876.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_002449877.1 identified by match to protein family HMM PF01037 YP_002449878.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_002449879.1 identified by match to protein family HMM PF00893 YP_002449880.1 identified by match to protein family HMM PF00893 YP_002449881.1 identified by match to protein family HMM PF00440 YP_002449882.1 identified by match to protein family HMM PF00083; match to protein family HMM PF05978; match to protein family HMM PF07690 YP_002449883.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01638 YP_002449884.1 identified by match to protein family HMM PF07366 YP_002449885.1 identified by match to protein family HMM PF02525 YP_002449887.1 identified by match to protein family HMM PF00496 YP_002449888.1 identified by match to protein family HMM PF07690 YP_002449889.1 identified by glimmer; putative YP_002449890.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_002449891.1 identified by match to protein family HMM PF00199; match to protein family HMM PF06628 YP_002449892.1 identified by match to protein family HMM PF05975 YP_002449893.1 identified by match to protein family HMM PF00324 YP_002449894.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00067 YP_002449896.1 identified by match to protein family HMM PF00171 YP_002449897.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002449898.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002449899.1 identified by match to protein family HMM PF00497 YP_002449900.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002449901.1 identified by match to protein family HMM PF00005 YP_002449902.1 identified by match to protein family HMM PF00269 YP_002449906.1 identified by match to protein family HMM PF04286 YP_002449907.1 identified by match to protein family HMM PF06133 YP_002449909.1 identified by match to protein family HMM PF08006 YP_002449910.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_002449911.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252 YP_002449912.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_002449913.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR01484 YP_002449914.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002449915.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01510 YP_002449916.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002449917.1 activates fatty acids by binding to coenzyme A YP_002449919.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF00955; match to protein family HMM PF01740 YP_002449920.1 identified by glimmer; putative YP_002449921.1 identified by glimmer; putative YP_002449923.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_002449924.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002449925.1 identified by match to protein family HMM PF04230 YP_002449926.1 identified by match to protein family HMM PF00395 YP_002449927.1 identified by match to protein family HMM PF00395 YP_002449929.1 identified by match to protein family HMM PF03062 YP_002449931.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002449933.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM TIGR01765 YP_002449934.1 identified by match to protein family HMM TIGR01766 YP_002449936.1 identified by glimmer; putative YP_002449937.1 identified by match to protein family HMM PF05343 YP_002449938.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01520 YP_002449939.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01170 YP_002449941.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF05544 YP_002449942.1 catalyzes the formation of L-proline from L-ornithine YP_002449945.1 identified by glimmer; putative YP_002449946.1 identified by glimmer; putative YP_002449948.1 identified by match to protein family HMM PF00496 YP_002449949.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00528 YP_002449950.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00528 YP_002449951.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449952.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002449953.1 identified by glimmer; putative YP_002449954.1 identified by glimmer; putative YP_002449955.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002449956.1 identified by match to protein family HMM PF02518 YP_002449957.1 identified by match to protein family HMM PF00072 YP_002449958.1 identified by match to protein family HMM PF03401 YP_002449959.1 identified by match to protein family HMM PF00589 YP_002449960.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002449961.1 identified by match to protein family HMM PF07728 YP_002449962.1 identified by glimmer; putative YP_002449966.1 identified by glimmer; putative YP_002449968.1 identified by match to protein family HMM PF01844 YP_002449971.1 identified by glimmer; putative YP_002449972.1 identified by glimmer; putative YP_002449973.1 identified by match to protein family HMM PF00376 YP_002449975.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002449976.1 unwinds double stranded DNA YP_002449977.1 identified by match to protein family HMM PF01978 YP_002449978.1 identified by match to protein family HMM PF01925 YP_002449980.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002449981.1 identified by glimmer; putative YP_002449983.1 identified by match to protein family HMM PF03551 YP_002449984.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002449986.1 identified by glimmer; putative YP_002449987.1 identified by match to protein family HMM PF03403 YP_002449988.1 identified by match to protein family HMM PF07336 YP_002449989.1 identified by match to protein family HMM PF04982 YP_002449990.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002449991.1 identified by glimmer; putative YP_002449992.1 identified by match to protein family HMM PF01047 YP_002449993.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473 YP_002449996.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01636 YP_002449998.1 identified by match to protein family HMM PF04892 YP_002449999.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone YP_002450000.1 identified by match to protein family HMM TIGR02366 YP_002450001.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_002450003.1 identified by glimmer; putative YP_002450004.1 identified by match to protein family HMM PF01966 YP_002450005.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002450006.1 identified by glimmer; putative YP_002450007.1 identified by glimmer; putative YP_002450008.1 identified by match to protein family HMM PF00395 YP_002450009.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450010.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450012.1 identified by glimmer; putative YP_002450015.1 identified by match to protein family HMM PF05532 YP_002450016.1 identified by match to protein family HMM PF04226 YP_002450017.1 identified by glimmer; putative YP_002450018.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377 YP_002450019.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_002450020.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase YP_002450021.1 identified by match to protein family HMM PF00210 YP_002450022.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00072; match to protein family HMM PF07228 YP_002450023.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705 YP_002450024.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01590; match to protein family HMM PF02518 YP_002450025.1 identified by glimmer; putative YP_002450026.1 identified by glimmer; putative YP_002450028.1 identified by glimmer; putative YP_002450029.1 identified by match to protein family HMM PF01906 YP_002450030.1 identified by glimmer; putative YP_002450031.1 identified by glimmer; putative YP_002450032.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002450034.1 identified by glimmer; putative YP_002450036.1 identified by match to protein family HMM PF00149 YP_002450037.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450038.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450039.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_002450042.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450043.1 identified by match to protein family HMM PF06013 YP_002450046.1 identified by match to protein family HMM PF00903 YP_002450047.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00903 YP_002450048.1 identified by match to protein family HMM PF00515 YP_002450050.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01527 YP_002450051.1 identified by match to protein family HMM PF00665 YP_002450052.1 identified by match to protein family HMM PF00561 YP_002450055.1 identified by glimmer; putative YP_002450056.1 identified by match to protein family HMM PF04309 YP_002450057.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002450058.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002450059.1 identified by match to protein family HMM PF01266 YP_002450060.1 identified by glimmer; putative YP_002450062.1 part of sigC operon induced by temperature upshift YP_002450063.1 part of sigC operon that is induced by temperature upshift YP_002450065.1 identified by match to protein family HMM PF01047 YP_002450066.1 identified by match to protein family HMM PF07681 YP_002450067.1 identified by match to protein family HMM PF07690 YP_002450068.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002450069.1 identified by glimmer; putative YP_002450070.1 identified by match to protein family HMM PF00580 YP_002450071.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002450073.1 identified by match to protein family HMM PF08963 YP_002450074.1 hpr; ScoC; MarR family; protease production regulatory protein YP_002450075.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450076.1 identified by match to protein family HMM PF01230 YP_002450077.1 identified by match to protein family HMM PF00005 YP_002450078.1 identified by match to protein family HMM PF05975 YP_002450083.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450085.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450089.1 identified by match to protein family HMM PF00440 YP_002450090.1 identified by glimmer; putative YP_002450091.1 identified by match to protein family HMM PF03703 YP_002450092.1 identified by match to protein family HMM PF03703 YP_002450093.1 identified by glimmer; putative YP_002450095.1 identified by match to protein family HMM PF06993 YP_002450097.1 identified by match to protein family HMM PF00805 YP_002450098.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278 YP_002450099.1 identified by glimmer; putative YP_002450100.1 identified by match to protein family HMM PF03703 YP_002450101.1 identified by match to protein family HMM PF03703 YP_002450102.1 identified by match to protein family HMM PF03992 YP_002450103.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002450104.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002450105.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002450106.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_002450107.1 identified by glimmer; putative YP_002450108.1 identified by match to protein family HMM PF03372 YP_002450109.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450111.1 identified by match to protein family HMM PF00440 YP_002450112.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002450115.1 identified by match to protein family HMM PF00583 YP_002450116.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002450118.1 identified by match to protein family HMM PF00753 YP_002450119.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545 YP_002450121.1 activates fatty acids by binding to coenzyme A YP_002450123.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_002450127.1 identified by glimmer; putative YP_002450129.1 identified by match to protein family HMM PF00395; match to protein family HMM PF05031 YP_002450130.1 identified by match to protein family HMM PF02018; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002450131.1 identified by glimmer; putative YP_002450132.1 identified by match to protein family HMM PF06877 YP_002450133.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450134.1 identified by glimmer; putative YP_002450138.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450140.1 identified by match to protein family HMM PF07968; match to protein family HMM TIGR01002 YP_002450141.1 identified by match to protein family HMM PF00149 YP_002450143.1 identified by match to protein family HMM PF01966 YP_002450145.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002450146.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002450147.1 identified by match to protein family HMM PF00903 YP_002450148.1 identified by glimmer; putative YP_002450149.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002450150.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450151.1 identified by match to protein family HMM PF02517 YP_002450153.1 identified by glimmer; putative YP_002450154.1 identified by glimmer; putative YP_002450155.1 identified by match to protein family HMM PF01435 YP_002450156.1 identified by match to protein family HMM PF00892 YP_002450157.1 identified by match to protein family HMM PF00395 YP_002450158.1 identified by glimmer; putative YP_002450159.1 identified by match to protein family HMM PF00395 YP_002450160.1 identified by match to protein family HMM PF00395 YP_002450161.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002450162.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_002450163.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450164.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450165.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00313 YP_002450166.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002450167.1 identified by glimmer; putative YP_002450168.1 identified by match to protein family HMM PF06338 YP_002450169.1 identified by match to protein family HMM PF09335 YP_002450170.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002450171.1 identified by match to protein family HMM TIGR02773 YP_002450172.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785 YP_002450180.1 identified by match to protein family HMM PF09388 YP_002450181.1 identified by match to protein family HMM PF01557 YP_002450182.1 identified by glimmer; putative YP_002450183.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR01885 YP_002450184.1 identified by match to protein family HMM PF07457 YP_002450186.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 YP_002450187.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002450188.1 identified by match to protein family HMM PF00199 YP_002450189.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_002450190.1 identified by match to protein family HMM PF00128 YP_002450191.1 identified by match to protein family HMM PF01381 YP_002450192.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002450194.1 identified by glimmer; putative YP_002450195.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002450197.1 identified by match to protein family HMM PF02588 YP_002450200.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002450201.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450202.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_002450205.1 identified by match to protein family HMM PF01370 YP_002450207.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002450208.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002450211.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002450212.1 identified by glimmer; putative YP_002450213.1 identified by match to protein family HMM PF00496 YP_002450214.1 identified by match to protein family HMM PF00528 YP_002450215.1 identified by match to protein family HMM PF00528 YP_002450216.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002450217.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002450218.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002450219.1 identified by match to protein family HMM PF00496 YP_002450220.1 identified by glimmer; putative YP_002450222.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002450223.1 identified by match to protein family HMM PF03741 YP_002450224.1 identified by glimmer; putative YP_002450225.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002450226.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002450227.1 identified by match to protein family HMM PF06054 YP_002450228.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002450229.1 identified by glimmer; putative YP_002450231.1 identified by match to protein family HMM PF01152 YP_002450232.1 identified by match to protein family HMM PF01928 YP_002450234.1 identified by match to protein family HMM PF04607 YP_002450235.1 catalyzes the phosphorylation of NAD to NADP YP_002450236.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002450237.1 identified by match to protein family HMM PF05658 YP_002450238.1 asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate YP_002450239.1 identified by match to protein family HMM PF01098 YP_002450240.1 identified by match to protein family HMM PF00535 YP_002450241.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002450242.1 identified by match to protein family HMM PF05711 YP_002450243.1 identified by match to protein family HMM PF01391 YP_002450244.1 identified by match to protein family HMM PF00535 YP_002450245.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002450246.1 identified by glimmer; putative YP_002450248.1 identified by match to protein family HMM PF00483 YP_002450249.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_002450250.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002450251.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214 YP_002450252.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002450255.1 identified by match to protein family HMM PF07098 YP_002450256.1 identified by glimmer; putative YP_002450257.1 identified by glimmer; putative YP_002450259.1 identified by match to protein family HMM PF00580 YP_002450260.1 identified by match to protein family HMM PF00583 YP_002450261.1 similar to 2'-5' RNA ligase YP_002450262.1 identified by match to protein family HMM PF00756 YP_002450263.1 identified by match to protein family HMM PF00892 YP_002450264.1 identified by match to protein family HMM PF06713 YP_002450266.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002450267.1 identified by glimmer; putative YP_002450268.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002450269.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002450270.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002450271.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_002450272.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_002450273.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002450274.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002450278.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002450281.1 identified by glimmer; putative YP_002450282.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002450284.1 identified by glimmer; putative YP_002450285.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992 YP_002450286.1 identified by match to protein family HMM PF00583 YP_002450287.1 identified by glimmer; putative YP_002450289.1 identified by match to protein family HMM PF02624 YP_002450290.1 identified by glimmer; putative YP_002450291.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002450292.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002450293.1 identified by match to protein family HMM PF01381 YP_002450295.1 identified by glimmer; putative YP_002450298.1 identified by match to protein family HMM PF06013 YP_002450299.1 identified by glimmer; putative YP_002450301.1 identified by glimmer; putative YP_002450303.1 identified by glimmer; putative YP_002450304.1 identified by glimmer; putative YP_002450307.1 identified by glimmer; putative YP_002450311.1 identified by match to protein family HMM PF00589 YP_002450312.1 identified by glimmer; putative YP_002450313.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002450314.1 identified by glimmer; putative YP_002450315.1 identified by match to protein family HMM PF00768 YP_002450316.1 identified by match to protein family HMM PF00665 YP_002450317.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01527 YP_002450318.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02228 YP_002450322.1 identified by match to protein family HMM PF01381; match to protein family HMM PF08671 YP_002450323.1 identified by match to protein family HMM PF08671 YP_002450324.1 identified by match to protein family HMM PF05547; match to protein family HMM TIGR03296 YP_002450325.1 identified by match to protein family HMM PF00171 YP_002450326.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR01187 YP_002450327.1 identified by match to protein family HMM PF00528 YP_002450328.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00528 YP_002450329.1 identified by match to protein family HMM PF01547 YP_002450330.1 identified by match to protein family HMM PF01569 YP_002450333.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002450334.1 identified by match to protein family HMM PF07853 YP_002450335.1 identified by match to protein family HMM PF00188; match to protein family HMM TIGR02909 YP_002450336.1 identified by match to protein family HMM PF02754 YP_002450337.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387 YP_002450338.1 identified by match to protein family HMM PF05651 YP_002450339.1 identified by match to protein family HMM TIGR02276 YP_002450340.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450341.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002450342.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002450343.1 identified by match to protein family HMM PF02754 YP_002450344.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_002450345.1 identified by match to protein family HMM PF02589 YP_002450346.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_002450348.1 identified by match to protein family HMM PF01226 YP_002450349.1 identified by match to protein family HMM PF03741 YP_002450350.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002450351.1 identified by match to protein family HMM PF00269 YP_002450352.1 identified by match to protein family HMM PF01575 YP_002450353.1 identified by match to protein family HMM PF09602; match to protein family HMM TIGR02131 YP_002450354.1 identified by match to protein family HMM PF03551; match to protein family HMM TIGR02719 YP_002450355.1 identified by match to protein family HMM TIGR02132 YP_002450356.1 catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis YP_002450357.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR01836 YP_002450358.1 identified by match to protein family HMM PF01266 YP_002450359.1 identified by match to protein family HMM PF02386 YP_002450360.1 identified by glimmer; putative YP_002450362.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR03261 YP_002450363.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03265 YP_002450364.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03262 YP_002450365.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002450366.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002450367.1 identified by match to protein family HMM PF03435 YP_002450368.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002450369.1 identified by glimmer; putative YP_002450370.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00395; match to protein family HMM PF05031 YP_002450371.1 identified by match to protein family HMM PF00596 YP_002450372.1 identified by match to protein family HMM PF00571 YP_002450373.1 identified by match to protein family HMM PF04748 YP_002450374.1 identified by match to protein family HMM PF09388 YP_002450375.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002450376.1 identified by match to protein family HMM PF01047 YP_002450377.1 identified by match to protein family HMM PF01432; match to protein family HMM TIGR02289 YP_002450379.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002450380.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002450381.1 identified by match to protein family HMM PF06508; match to protein family HMM TIGR00364 YP_002450382.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR03367 YP_002450383.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR03365 YP_002450384.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_002450386.1 identified by glimmer; putative YP_002450388.1 identified by match to protein family HMM PF00583 YP_002450390.1 identified by glimmer; putative YP_002450391.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002450392.1 identified by match to protein family HMM PF00317 YP_002450393.1 identified by match to protein family HMM PF01541; match to protein family HMM PF07460; match to protein family HMM TIGR01453 YP_002450394.1 identified by match to protein family HMM PF02867 YP_002450395.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002450396.1 identified by match to protein family HMM PF00392 YP_002450397.1 identified by match to protein family HMM PF00005 YP_002450399.1 identified by match to protein family HMM PF00005 YP_002450401.1 identified by match to protein family HMM PF02517 YP_002450402.1 identified by glimmer; putative YP_002450403.1 identified by match to protein family HMM PF01037 YP_002450405.1 identified by match to protein family HMM PF00857 YP_002450407.1 identified by match to protein family HMM PF02016 YP_002450408.1 identified by match to protein family HMM PF01180; match to protein family HMM PF03060 YP_002450409.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002450410.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_002450411.1 identified by match to protein family HMM PF03062 YP_002450412.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_002450413.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450414.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002450415.1 identified by glimmer; putative YP_002450416.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002450417.1 identified by glimmer; putative YP_002450418.1 identified by glimmer; putative YP_002450419.1 identified by match to protein family HMM PF01636 YP_002450421.1 identified by glimmer; putative YP_002450422.1 identified by glimmer; putative YP_002450423.1 identified by glimmer; putative YP_002450424.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002450425.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002450427.1 identified by glimmer; putative YP_002450428.1 identified by match to protein family HMM PF01047 YP_002450429.1 identified by glimmer; putative YP_002450430.1 identified by match to protein family HMM PF00375 YP_002450431.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002450433.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002450434.1 identified by glimmer; putative YP_002450435.1 identified by match to protein family HMM PF03698 YP_002450436.1 identified by glimmer; putative YP_002450437.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002450438.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002450439.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002450440.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002450441.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002450442.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002450443.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002450444.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002450445.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002450446.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_002450447.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_002450448.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002450449.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_002450450.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002450451.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002450452.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002450453.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_002450454.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_002450455.1 catalyzes the formation of L-histidinol from L-histidinol phosphate YP_002450456.1 identified by glimmer; putative YP_002450457.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002450458.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473 YP_002450459.1 identified by match to protein family HMM PF00884 YP_002450460.1 identified by glimmer; putative YP_002450461.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048 YP_002450463.1 identified by match to protein family HMM PF01507; match to protein family HMM TIGR00434; match to protein family HMM TIGR02055 YP_002450464.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_002450465.1 identified by match to protein family HMM PF01583; match to protein family HMM TIGR00455 YP_002450466.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460 YP_002450467.1 identified by glimmer; putative YP_002450468.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_002450469.1 identified by match to protein family HMM PF01903 YP_002450470.1 catalyzes the formation of siroheme from precorrin-2 YP_002450471.1 identified by match to protein family HMM PF00209 YP_002450472.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01527 YP_002450473.1 identified by match to protein family HMM PF00665 YP_002450474.1 identified by match to protein family HMM PF01551 YP_002450475.1 identified by match to protein family HMM PF00375 YP_002450476.1 identified by match to protein family HMM PF04167 YP_002450477.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600 YP_002450479.1 identified by match to protein family HMM PF04012 YP_002450481.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002450482.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002450483.1 identified by glimmer; putative YP_002450484.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002450486.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002450488.1 identified by glimmer; putative YP_002450489.1 identified by match to protein family HMM PF02163 YP_002450491.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002450492.1 identified by match to protein family HMM PF00027 YP_002450493.1 identified by glimmer; putative YP_002450494.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450495.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450496.1 identified by match to protein family HMM PF01384 YP_002450497.1 identified by match to protein family HMM PF01865 YP_002450498.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002450500.1 identified by match to protein family HMM PF01391 YP_002450501.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002450502.1 identified by match to protein family HMM PF01904 YP_002450503.1 identified by glimmer; putative YP_002450504.1 identified by match to protein family HMM PF00589 YP_002450505.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002450506.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002450507.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002450509.1 identified by match to protein family HMM PF03706; match to protein family HMM PF04329; match to protein family HMM PF04330; match to protein family HMM PF04331 YP_002450510.1 identified by glimmer; putative YP_002450512.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002450513.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002450514.1 identified by match to protein family HMM PF07670 YP_002450515.1 identified by match to protein family HMM PF07670 YP_002450516.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002450517.1 catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c YP_002450518.1 identified by match to protein family HMM PF05140 YP_002450519.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144 YP_002450520.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450521.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002450522.1 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636 YP_002450523.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_002450524.1 identified by glimmer; putative YP_002450525.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450526.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450527.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450530.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614 YP_002450531.1 identified by match to protein family HMM PF02517 YP_002450532.1 identified by match to protein family HMM PF01476 YP_002450533.1 identified by match to protein family HMM PF00149 YP_002450534.1 identified by match to protein family HMM PF00376 YP_002450535.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002450536.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002450537.1 identified by glimmer; putative YP_002450538.1 identified by glimmer; putative YP_002450539.1 identified by match to protein family HMM PF01510 YP_002450540.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002450541.1 identified by match to protein family HMM PF00710 YP_002450542.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002450543.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002450544.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_002450545.1 identified by glimmer; putative YP_002450549.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002450550.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002450554.1 identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836 YP_002450555.1 identified by match to protein family HMM PF00216 YP_002450556.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002450557.1 identified by match to protein family HMM PF07307 YP_002450558.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002450559.1 identified by match to protein family HMM PF00348; match to protein family HMM TIGR02748 YP_002450560.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002450561.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002450562.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002450563.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002450564.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07720 YP_002450565.1 identified by match to protein family HMM PF08858; match to protein family HMM PF08864 YP_002450567.1 identified by match to protein family HMM PF00355 YP_002450568.1 electron transport protein YP_002450570.1 identified by match to protein family HMM PF07187 YP_002450571.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906 YP_002450572.1 identified by match to protein family HMM PF09577; match to protein family HMM TIGR02878 YP_002450573.1 identified by match to protein family HMM PF04298 YP_002450574.1 identified by match to protein family HMM PF03167 YP_002450575.1 identified by match to protein family HMM PF02588 YP_002450576.1 identified by match to protein family HMM PF03819 YP_002450577.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002450578.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002450579.1 identified by match to protein family HMM PF02585 YP_002450580.1 identified by match to protein family HMM PF00534 YP_002450581.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_002450582.1 identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM PF08279; match to protein family HMM TIGR00121; match to protein family HMM TIGR00122 YP_002450584.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002450585.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002450586.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002450587.1 unwinds DNA YP_002450589.1 identified by match to protein family HMM PF03413 YP_002450590.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002450591.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002450592.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083 YP_002450594.1 identified by match to protein family HMM PF00041; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002450595.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_002450597.1 identified by glimmer; putative YP_002450598.1 identified by glimmer; putative YP_002450599.1 identified by match to protein family HMM PF08807 YP_002450603.1 identified by match to protein family HMM PF06908 YP_002450604.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544 YP_002450605.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02926 YP_002450606.1 identified by glimmer; putative YP_002450608.1 identified by match to protein family HMM PF02074 YP_002450609.1 identified by match to protein family HMM PF00583 YP_002450610.1 identified by match to protein family HMM PF01636 YP_002450611.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002450612.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_002450613.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002450614.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002450615.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450616.1 identified by match to protein family HMM PF00350; match to protein family HMM PF01926 YP_002450617.1 identified by glimmer; putative YP_002450618.1 identified by match to protein family HMM PF00583 YP_002450620.1 identified by match to protein family HMM PF00581 YP_002450621.1 identified by glimmer; putative YP_002450623.1 identified by match to protein family HMM PF03738 YP_002450624.1 identified by match to protein family HMM PF03994 YP_002450626.1 identified by match to protein family HMM PF01367; match to protein family HMM PF02739 YP_002450628.1 identified by match to protein family HMM PF01757 YP_002450629.1 identified by match to protein family HMM PF02706 YP_002450631.1 identified by match to protein family HMM PF02397 YP_002450632.1 identified by match to protein family HMM PF01943 YP_002450633.1 identified by match to protein family HMM PF04932 YP_002450634.1 identified by match to protein family HMM PF00535 YP_002450635.1 identified by match to protein family HMM PF00534 YP_002450636.1 identified by glimmer; putative YP_002450637.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451 YP_002450638.1 identified by match to protein family HMM PF00583 YP_002450639.1 identified by match to protein family HMM PF00857 YP_002450640.1 identified by glimmer; putative YP_002450641.1 identified by match to protein family HMM PF00892 YP_002450642.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002450643.1 identified by match to protein family HMM PF01263 YP_002450644.1 identified by match to protein family HMM PF06177 YP_002450648.1 identified by match to protein family HMM PF00313 YP_002450649.1 identified by match to protein family HMM PF08892 YP_002450650.1 identified by match to protein family HMM PF01810 YP_002450651.1 identified by glimmer; putative YP_002450652.1 identified by match to protein family HMM PF04116 YP_002450653.1 identified by match to protein family HMM PF04341 YP_002450654.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813 YP_002450655.1 identified by match to protein family HMM PF00202 YP_002450656.1 identified by glimmer; putative YP_002450657.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00932 YP_002450658.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002450659.1 identified by match to protein family HMM PF00376 YP_002450660.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002450661.1 identified by match to protein family HMM PF04239 YP_002450662.1 identified by match to protein family HMM PF02698 YP_002450664.1 identified by match to protein family HMM PF00881 YP_002450665.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450666.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450667.1 identified by match to protein family HMM PF01925 YP_002450668.1 identified by match to protein family HMM PF07690 YP_002450669.1 identified by match to protein family HMM PF01022 YP_002450670.1 identified by match to protein family HMM PF07690 YP_002450671.1 identified by match to protein family HMM PF00903 YP_002450672.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002450673.1 identified by match to protein family HMM PF09388 YP_002450674.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383 YP_002450675.1 identified by match to protein family HMM PF01966 YP_002450676.1 Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_002450677.1 Homolog to MotB, appears to be involved in motility on surfaces and under specific ionic conditions. With MotP (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002450678.1 identified by match to protein family HMM PF00072 YP_002450679.1 identified by match to protein family HMM PF01584; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF02895; match to protein family HMM PF07194 YP_002450680.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002450681.1 identified by glimmer; putative YP_002450682.1 identified by glimmer; putative YP_002450683.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705 YP_002450687.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002450688.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_002450689.1 involved in flagellin assembly YP_002450692.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_002450693.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002450694.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002450695.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002450696.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002450697.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002450698.1 involved in type III protein export during flagellum assembly YP_002450701.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod YP_002450702.1 the hook connects flagellar basal body to the flagellar filament YP_002450705.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584 YP_002450707.1 identified by match to protein family HMM PF00669; match to protein family HMM PF00700 YP_002450708.1 structural flagella protein YP_002450709.1 identified by match to protein family HMM PF01464 YP_002450710.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002450711.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002450712.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002450714.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002450715.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002450716.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_002450717.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002450718.1 membrane protein involved in the flagellar export apparatus YP_002450719.1 positive regulator of class III flagellar genes YP_002450720.1 makes up the distal portion of the flagellar basal body rod YP_002450721.1 identified by match to protein family HMM PF07973 YP_002450722.1 identified by match to protein family HMM PF01978 YP_002450723.1 identified by match to protein family HMM PF03591 YP_002450724.1 identified by match to protein family HMM PF05437 YP_002450725.1 identified by glimmer; putative YP_002450726.1 identified by match to protein family HMM PF00440 YP_002450729.1 identified by match to protein family HMM PF01738 YP_002450730.1 identified by match to protein family HMM PF03992 YP_002450731.1 identified by match to protein family HMM PF08141; match to protein family HMM TIGR02861 YP_002450732.1 identified by match to protein family HMM PF01381 YP_002450733.1 identified by match to protein family HMM PF07690 YP_002450735.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002450736.1 identified by match to protein family HMM PF00005 YP_002450737.1 identified by match to protein family HMM PF01547 YP_002450738.1 identified by match to protein family HMM PF00528 YP_002450739.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521 YP_002450742.1 identified by glimmer; putative YP_002450743.1 identified by match to protein family HMM PF00190 YP_002450746.1 identified by match to protein family HMM PF00300 YP_002450747.1 identified by glimmer; putative YP_002450748.1 identified by match to protein family HMM PF00561 YP_002450750.1 identified by match to protein family HMM PF01047 YP_002450752.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00733 YP_002450753.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00310 YP_002450754.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002450756.1 identified by match to protein family HMM PF02012 YP_002450757.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002450758.1 identified by glimmer; putative YP_002450759.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002450760.1 identified by match to protein family HMM PF00892 YP_002450761.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002450762.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450763.1 identified by match to protein family HMM PF03773 YP_002450764.1 identified by match to protein family HMM PF09323 YP_002450766.1 identified by glimmer; putative YP_002450767.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002450768.1 identified by match to protein family HMM PF00376 YP_002450769.1 identified by match to protein family HMM PF00106 YP_002450770.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002450771.1 identified by glimmer; putative YP_002450772.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450774.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002450775.1 identified by match to protein family HMM PF03575 YP_002450776.1 identified by glimmer; putative YP_002450777.1 identified by match to protein family HMM PF03965 YP_002450778.1 identified by match to protein family HMM PF01435; match to protein family HMM PF05569 YP_002450779.1 identified by match to protein family HMM PF02683 YP_002450780.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002450782.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002450783.1 identified by match to protein family HMM TIGR01765; match to protein family HMM TIGR01766 YP_002450784.1 catalyzes the formation of pyruvate from serine YP_002450785.1 identified by match to protein family HMM PF04286 YP_002450788.1 identified by glimmer; putative YP_002450789.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in B. thuringiensis this protein is involved in beta-exotoxin I production YP_002450790.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002450791.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002450792.1 identified by match to protein family HMM PF00005 YP_002450793.1 identified by match to protein family HMM PF01061 YP_002450794.1 identified by match to protein family HMM PF01061 YP_002450795.1 identified by match to protein family HMM PF00614 YP_002450796.1 Catalyzes the phosphorylation of UMP to UDP YP_002450797.1 identified by match to protein family HMM PF00375 YP_002450798.1 catalyzes the formation of fumarate from aspartate YP_002450799.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002450800.1 identified by match to protein family HMM PF02518 YP_002450801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08664 YP_002450802.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455 YP_002450803.1 identified by glimmer; putative YP_002450804.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002450805.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002450806.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002450807.1 identified by match to protein family HMM PF00903 YP_002450808.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_002450812.1 identified by match to protein family HMM PF00293 YP_002450813.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01520 YP_002450814.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01832 YP_002450815.1 identified by match to protein family HMM PF07690 YP_002450816.1 identified by glimmer; putative YP_002450818.1 identified by match to protein family HMM PF02554 YP_002450819.1 identified by match to protein family HMM PF03976 YP_002450820.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002450821.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_002450823.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR03156 YP_002450824.1 identified by match to protein family HMM PF00496 YP_002450825.1 identified by match to protein family HMM PF07690 YP_002450826.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002450827.1 identified by match to protein family HMM PF00583 YP_002450829.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002450830.1 identified by match to protein family HMM PF00209 YP_002450831.1 identified by match to protein family HMM PF01522 YP_002450833.1 identified by match to protein family HMM PF04239 YP_002450834.1 identified by glimmer; putative YP_002450835.1 identified by match to protein family HMM PF07299 YP_002450836.1 identified by match to protein family HMM PF01625; match to protein family HMM TIGR00401 YP_002450837.1 identified by match to protein family HMM PF00106 YP_002450838.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002450839.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002450840.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small subunit YP_002450841.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002450842.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002450843.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_002450844.1 identified by match to protein family HMM PF09587 YP_002450845.1 identified by match to protein family HMM PF04474 YP_002450847.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002450848.1 identified by match to protein family HMM PF02900 YP_002450849.1 identified by match to protein family HMM PF00561 YP_002450850.1 identified by match to protein family HMM PF04397 YP_002450851.1 identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458 YP_002450852.1 identified by match to protein family HMM PF00583 YP_002450854.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002450856.1 identified by match to protein family HMM PF00496 YP_002450857.1 identified by glimmer; putative YP_002450859.1 identified by glimmer; putative YP_002450860.1 identified by glimmer; putative YP_002450861.1 identified by match to protein family HMM PF04055 YP_002450862.1 identified by match to protein family HMM PF00583 YP_002450863.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450864.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002450865.1 identified by match to protein family HMM PF01551 YP_002450866.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_002450867.1 identified by match to protein family HMM PF00581 YP_002450868.1 identified by glimmer; putative YP_002450869.1 identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745 YP_002450871.1 identified by glimmer; putative YP_002450873.1 identified by match to protein family HMM PF05791 YP_002450874.1 identified by match to protein family HMM PF05791 YP_002450875.1 identified by match to protein family HMM PF05791 YP_002450876.1 identified by match to protein family HMM PF01810 YP_002450877.1 identified by match to protein family HMM PF04198 YP_002450878.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002450879.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002450880.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002450881.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002450883.1 identified by match to protein family HMM PF05979 YP_002450885.1 identified by match to protein family HMM PF02683 YP_002450886.1 identified by match to protein family HMM PF02012 YP_002450887.1 identified by match to protein family HMM PF00557; match to protein family HMM PF05195 YP_002450888.1 identified by match to protein family HMM PF00394; match to protein family HMM PF07731; match to protein family HMM PF07732 YP_002450889.1 identified by match to protein family HMM PF00018; match to protein family HMM PF01551; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002450891.1 decatenates replicating daughter chromosomes YP_002450893.1 identified by match to protein family HMM PF07690 YP_002450894.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01758 YP_002450895.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002450896.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002450897.1 identified by match to protein family HMM PF00903 YP_002450898.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002450899.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002450900.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05425 YP_002450901.1 identified by match to protein family HMM PF07987 YP_002450902.1 identified by match to protein family HMM PF00892 YP_002450903.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002450904.1 identified by match to protein family HMM PF02082 YP_002450905.1 identified by match to protein family HMM PF01323 YP_002450906.1 identified by match to protein family HMM PF00881 YP_002450908.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002450909.1 identified by match to protein family HMM PF01594 YP_002450910.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002450911.1 identified by match to protein family HMM PF01593 YP_002450912.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002450913.1 identified by match to protein family HMM PF00395 YP_002450914.1 identified by match to protein family HMM PF00440 YP_002450915.1 activates fatty acids by binding to coenzyme A YP_002450916.1 identified by match to protein family HMM PF01575 YP_002450917.1 identified by match to protein family HMM PF08541; match to protein family HMM PF08545 YP_002450918.1 identified by match to protein family HMM PF01094 YP_002450919.1 identified by match to protein family HMM PF00005 YP_002450920.1 identified by match to protein family HMM PF00005 YP_002450921.1 identified by match to protein family HMM PF02653 YP_002450922.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02653 YP_002450923.1 identified by match to protein family HMM PF00126 YP_002450926.1 identified by match to protein family HMM PF02627 YP_002450927.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03551 YP_002450928.1 identified by match to protein family HMM PF00296 YP_002450929.1 identified by match to protein family HMM PF01654 YP_002450930.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002450931.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02857 YP_002450932.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02868 YP_002450933.1 identified by glimmer; putative YP_002450935.1 identified by match to protein family HMM PF02016 YP_002450936.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768 YP_002450937.1 identified by match to protein family HMM PF00881 YP_002450939.1 identified by match to protein family HMM PF00877; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002450940.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00561 YP_002450941.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002450942.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450943.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002450944.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002450946.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002450947.1 identified by glimmer; putative YP_002450948.1 identified by match to protein family HMM PF04439 YP_002450949.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01522 YP_002450951.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00293 YP_002450952.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01243 YP_002450953.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002450954.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002450955.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002450957.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002450958.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002450959.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002450960.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002450961.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002450962.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01522 YP_002450964.1 identified by match to protein family HMM PF02308 YP_002450965.1 identified by match to protein family HMM PF00583 YP_002450966.1 identified by match to protein family HMM PF04183 YP_002450967.1 identified by match to protein family HMM PF04183 YP_002450968.1 activates fatty acids by binding to coenzyme A YP_002450969.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_002450971.1 identified by match to protein family HMM PF01261 YP_002450972.1 identified by match to protein family HMM PF00269 YP_002450973.1 identified by match to protein family HMM PF07690 YP_002450974.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01810 YP_002450975.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002450976.1 identified by match to protein family HMM PF01734 YP_002450977.1 identified by match to protein family HMM PF09234 YP_002450979.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002450980.1 identified by match to protein family HMM PF00293 YP_002450981.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002450982.1 identified by glimmer; putative YP_002450983.1 identified by match to protein family HMM PF02687 YP_002450984.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002450985.1 identified by match to protein family HMM PF00082 YP_002450986.1 identified by match to protein family HMM PF01022 YP_002450987.1 identified by match to protein family HMM PF00248 YP_002450988.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002450992.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002450993.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002450994.1 identified by glimmer; putative YP_002450995.1 identified by glimmer; putative YP_002450997.1 identified by match to protein family HMM PF00210 YP_002450998.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002450999.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451000.1 identified by glimmer; putative YP_002451001.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558 YP_002451002.1 identified by glimmer; putative YP_002451003.1 identified by match to protein family HMM PF01593 YP_002451004.1 identified by match to protein family HMM PF00583 YP_002451005.1 identified by match to protein family HMM PF00248 YP_002451006.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002451007.1 identified by match to protein family HMM PF00583 YP_002451008.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by glimmer; putative YP_002451009.1 identified by glimmer; putative YP_002451010.1 identified by glimmer; putative YP_002451011.1 identified by glimmer; putative YP_002451012.1 identified by glimmer; putative YP_002451014.1 identified by glimmer; putative YP_002451016.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01297 YP_002451017.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002451018.1 identified by glimmer; putative YP_002451019.1 identified by match to protein family HMM PF01370 YP_002451020.1 catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds YP_002451021.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002451022.1 identified by glimmer; putative YP_002451023.1 identified by match to protein family HMM PF00496 YP_002451024.1 catalyzes resistance to fosfomycin by the addition of a thiol cofactor YP_002451026.1 identified by match to protein family HMM PF00300 YP_002451027.1 identified by glimmer; putative YP_002451028.1 identified by match to protein family HMM PF08757 YP_002451029.1 identified by match to protein family HMM PF00293 YP_002451030.1 identified by match to protein family HMM PF09335 YP_002451031.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002451032.1 identified by match to protein family HMM PF01544 YP_002451033.1 identified by glimmer; putative YP_002451034.1 identified by match to protein family HMM PF03773 YP_002451035.1 identified by match to protein family HMM PF09323 YP_002451036.1 identified by match to protein family HMM PF03061 YP_002451037.1 identified by match to protein family HMM PF00614 YP_002451038.1 identified by match to protein family HMM PF07875 YP_002451040.1 identified by match to protein family HMM PF02254 YP_002451041.1 identified by match to protein family HMM PF04306 YP_002451042.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002451044.1 identified by match to protein family HMM PF00571 YP_002451045.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002451046.1 identified by match to protein family HMM PF01588; match to protein family HMM TIGR02222 YP_002451047.1 identified by match to protein family HMM PF07609 YP_002451048.1 identified by glimmer; putative YP_002451049.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867 YP_002451050.1 identified by match to protein family HMM PF00583 YP_002451051.1 identified by match to protein family HMM PF02557 YP_002451052.1 identified by match to protein family HMM PF00293 YP_002451053.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002451054.1 identified by match to protein family HMM PF07690 YP_002451055.1 identified by match to protein family HMM PF01957 YP_002451056.1 identified by match to protein family HMM PF01145 YP_002451057.1 identified by match to protein family HMM PF00300 YP_002451058.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002451059.1 identified by glimmer; putative YP_002451060.1 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492 YP_002451061.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451062.1 identified by match to protein family HMM PF00583 YP_002451064.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002451065.1 identified by match to protein family HMM PF02588 YP_002451066.1 identified by match to protein family HMM PF00392 YP_002451067.1 identified by match to protein family HMM PF00583 YP_002451068.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00149 YP_002451069.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451070.1 identified by match to protein family HMM PF00583 YP_002451072.1 identified by match to protein family HMM PF00583 YP_002451074.1 identified by glimmer; putative YP_002451076.1 identified by glimmer; putative YP_002451077.1 identified by glimmer; putative YP_002451078.1 identified by glimmer; putative YP_002451079.1 identified by glimmer; putative YP_002451081.1 identified by glimmer; putative YP_002451083.1 identified by glimmer; putative YP_002451084.1 identified by glimmer; putative YP_002451085.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002451087.1 identified by glimmer; putative YP_002451088.1 identified by glimmer; putative YP_002451090.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451091.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_002451093.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002451095.1 identified by match to protein family HMM PF00903 YP_002451097.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002451098.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002451099.1 identified by glimmer; putative YP_002451100.1 identified by match to protein family HMM PF03109 YP_002451101.1 identified by glimmer; putative YP_002451102.1 identified by match to protein family HMM PF00753 YP_002451103.1 identified by glimmer; putative YP_002451104.1 identified by match to protein family HMM PF00255 YP_002451105.1 identified by match to protein family HMM PF01841 YP_002451106.1 identified by match to protein family HMM PF01882 YP_002451107.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002451108.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002451109.1 identified by match to protein family HMM TIGR01660 YP_002451110.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002451111.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002451112.1 identified by match to protein family HMM PF00392 YP_002451113.1 identified by match to protein family HMM PF00005 YP_002451114.1 identified by glimmer; putative YP_002451115.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325 YP_002451116.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002451117.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002451118.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002451119.1 identified by match to protein family HMM PF02391 YP_002451120.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002451121.1 identified by match to protein family HMM PF07690 YP_002451122.1 identified by match to protein family HMM PF03547 YP_002451123.1 catalyzes the formation of siroheme from precorrin-2 YP_002451124.1 identified by match to protein family HMM PF01903 YP_002451125.1 this protein contains the C-terminal section of uroporphyrinogen-III methyltransferase fused with uroporphyrinogen-III synthase; studies on Clostridium josui indicate that this protein has uroporphyrinogen-III methylase activity; functions in tetrapyrrole and heme biosynthesis YP_002451126.1 identified by match to protein family HMM PF00355; match to protein family HMM TIGR02378 YP_002451127.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_002451128.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04405 YP_002451129.1 identified by glimmer; putative YP_002451130.1 identified by match to protein family HMM PF05901 YP_002451131.1 identified by glimmer; putative YP_002451132.1 identified by glimmer; putative YP_002451133.1 identified by match to protein family HMM PF00797 YP_002451134.1 identified by match to protein family HMM PF07819 YP_002451135.1 identified by match to protein family HMM PF04232 YP_002451136.1 identified by glimmer; putative YP_002451138.1 identified by glimmer; putative YP_002451139.1 identified by match to protein family HMM PF01966 YP_002451140.1 identified by match to protein family HMM PF00005 YP_002451141.1 identified by match to protein family HMM PF06539 YP_002451142.1 identified by glimmer; putative YP_002451143.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002451144.1 identified by match to protein family HMM PF03130 YP_002451145.1 identified by glimmer; putative YP_002451146.1 identified by match to protein family HMM PF06491 YP_002451148.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002451149.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451150.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002451151.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_002451152.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002451153.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002451154.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01225; match to protein family HMM PF08245 YP_002451155.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002451159.1 identified by match to protein family HMM PF01580 YP_002451160.1 identified by match to protein family HMM PF06013 YP_002451161.1 identified by match to protein family HMM PF00515 YP_002451165.1 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741 YP_002451166.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451171.1 identified by match to protein family HMM PF09346 YP_002451172.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002451173.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_002451174.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002451175.1 identified by glimmer; putative YP_002451176.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451177.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741 YP_002451179.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451182.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002451183.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002451187.1 identified by glimmer; putative YP_002451188.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002451189.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00939 YP_002451190.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002451191.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002451192.1 identified by match to protein family HMM PF03413 YP_002451193.1 identified by match to protein family HMM PF03413 YP_002451194.1 identified by match to protein family HMM PF00209 YP_002451195.1 identified by match to protein family HMM PF00561 YP_002451196.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF06042 YP_002451198.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002451199.1 identified by match to protein family HMM PF03600 YP_002451200.1 identified by match to protein family HMM PF00465 YP_002451201.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002451202.1 identified by match to protein family HMM PF01980 YP_002451203.1 identified by match to protein family HMM PF00583 YP_002451204.1 identified by match to protein family HMM TIGR01656; match to protein family HMM TIGR01662 YP_002451205.1 identified by match to protein family HMM PF00583 YP_002451206.1 identified by match to protein family HMM PF00005 YP_002451209.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002451210.1 identified by match to protein family HMM PF00903 YP_002451211.1 identified by match to protein family HMM PF01636 YP_002451212.1 identified by match to protein family HMM PF00144 YP_002451213.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002451214.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00186 YP_002451215.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223 YP_002451216.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002451217.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002451218.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002451219.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002451220.1 identified by match to protein family HMM PF00902; match to protein family HMM TIGR00945 YP_002451222.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002451224.1 identified by match to protein family HMM PF02630 YP_002451225.1 identified by match to protein family HMM PF00011; match to protein family HMM PF04969 YP_002451226.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 YP_002451227.1 identified by match to protein family HMM PF00583 YP_002451228.1 identified by glimmer; putative YP_002451230.1 identified by match to protein family HMM PF01497 YP_002451231.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_002451232.1 identified by match to protein family HMM PF00881 YP_002451234.1 identified by glimmer; putative YP_002451235.1 identified by match to protein family HMM PF00857 YP_002451236.1 identified by match to protein family HMM PF00293 YP_002451237.1 identified by match to protein family HMM PF00011 YP_002451238.1 identified by match to protein family HMM PF00924 YP_002451239.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002451240.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002451241.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002451242.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01380 YP_002451243.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002451244.1 identified by match to protein family HMM PF00528 YP_002451245.1 identified by match to protein family HMM PF00528 YP_002451246.1 identified by match to protein family HMM PF00144 YP_002451247.1 identified by match to protein family HMM PF05139 YP_002451248.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002451249.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002451250.1 identified by match to protein family HMM PF00535 YP_002451252.1 identified by match to protein family HMM PF03358 YP_002451253.1 identified by match to protein family HMM PF07690 YP_002451254.1 identified by match to protein family HMM PF02698 YP_002451255.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01186 YP_002451256.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069 YP_002451257.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002451259.1 identified by match to protein family HMM PF07728 YP_002451260.1 identified by glimmer; putative YP_002451261.1 identified by glimmer; putative YP_002451262.1 remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions YP_002451263.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002451264.1 identified by match to protein family HMM PF00171 YP_002451265.1 identified by match to protein family HMM PF07997 YP_002451266.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09385 YP_002451268.1 identified by glimmer; putative YP_002451269.1 identified by match to protein family HMM PF00202 YP_002451270.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429 YP_002451271.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428 YP_002451272.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_002451273.1 identified by match to protein family HMM PF00583 YP_002451274.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002451275.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_002451277.1 identified by match to protein family HMM PF06855 YP_002451279.1 identified by glimmer; putative YP_002451281.1 identified by glimmer; putative YP_002451283.1 identified by match to protein family HMM PF07070 YP_002451284.1 identified by match to protein family HMM PF01569 YP_002451285.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002451286.1 identified by match to protein family HMM PF00085 YP_002451287.1 identified by match to protein family HMM PF00589 YP_002451288.1 identified by match to protein family HMM PF09346 YP_002451289.1 identified by match to protein family HMM PF06013 YP_002451290.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00395 YP_002451291.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002451292.1 identified by match to protein family HMM PF04471 YP_002451293.1 identified by match to protein family HMM PF01381 YP_002451294.1 identified by glimmer; putative YP_002451295.1 identified by match to protein family HMM PF01580 YP_002451296.1 identified by glimmer; putative YP_002451297.1 identified by glimmer; putative YP_002451298.1 identified by glimmer; putative YP_002451299.1 identified by match to protein family HMM PF01042 YP_002451300.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002451303.1 identified by glimmer; putative YP_002451305.1 identified by glimmer; putative YP_002451306.1 identified by glimmer; putative YP_002451307.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002451308.1 identified by glimmer; putative YP_002451309.1 identified by glimmer; putative YP_002451310.1 identified by match to protein family HMM PF08863 YP_002451312.1 identified by glimmer; putative YP_002451313.1 identified by match to protein family HMM PF01679 YP_002451314.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002451315.1 identified by match to protein family HMM PF07690 YP_002451316.1 identified by match to protein family HMM PF01521 YP_002451317.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration YP_002451318.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_002451319.1 identified by match to protein family HMM TIGR02317 YP_002451321.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002451322.1 identified by match to protein family HMM PF03446; match to protein family HMM PF03807 YP_002451323.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722 YP_002451324.1 identified by match to protein family HMM PF01810 YP_002451325.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_002451326.1 identified by glimmer; putative YP_002451328.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00619 YP_002451329.1 identified by match to protein family HMM PF02463 YP_002451330.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451331.1 identified by glimmer; putative YP_002451332.1 identified by match to protein family HMM PF01022 YP_002451334.1 identified by glimmer; putative YP_002451335.1 identified by match to protein family HMM PF07690 YP_002451336.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002451337.1 synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis YP_002451338.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR02275 YP_002451339.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857 YP_002451340.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733 YP_002451341.1 identified by match to protein family HMM PF03621 YP_002451342.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002451343.1 identified by match to protein family HMM PF01648 YP_002451345.1 identified by match to protein family HMM PF00216 YP_002451347.1 identified by match to protein family HMM PF05163 YP_002451348.1 identified by match to protein family HMM PF00082 YP_002451349.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002451350.1 identified by glimmer; putative YP_002451351.1 identified by glimmer; putative YP_002451353.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002451354.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451355.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins YP_002451356.1 identified by match to protein family HMM PF00005 YP_002451357.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451358.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451359.1 identified by match to protein family HMM PF00561 YP_002451362.1 identified by match to protein family HMM PF02535 YP_002451363.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451364.1 identified by match to protein family HMM PF00753 YP_002451365.1 identified by match to protein family HMM PF01156 YP_002451366.1 identified by glimmer; putative YP_002451368.1 identified by match to protein family HMM PF04657 YP_002451369.1 identified by match to protein family HMM PF00027 YP_002451370.1 identified by match to protein family HMM PF04657 YP_002451371.1 identified by match to protein family HMM PF00583 YP_002451372.1 identified by match to protein family HMM PF00753 YP_002451373.1 identified by match to protein family HMM PF00440 YP_002451374.1 identified by match to protein family HMM PF03176 YP_002451375.1 identified by glimmer; putative YP_002451376.1 identified by match to protein family HMM PF00302 YP_002451377.1 identified by match to protein family HMM PF00583 YP_002451378.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00583 YP_002451379.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00805 YP_002451380.1 identified by match to protein family HMM PF00583 YP_002451381.1 identified by match to protein family HMM PF00892; match to protein family HMM PF08449 YP_002451382.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002451383.1 identified by glimmer; putative YP_002451384.1 identified by glimmer; putative YP_002451385.1 identified by match to protein family HMM PF00561 YP_002451386.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_002451387.1 identified by glimmer; putative YP_002451388.1 identified by match to protein family HMM PF00583 YP_002451390.1 identified by match to protein family HMM PF00313 YP_002451391.1 identified by match to protein family HMM PF02517 YP_002451394.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002451395.1 identified by glimmer; putative YP_002451396.1 identified by glimmer; putative YP_002451397.1 identified by glimmer; putative YP_002451398.1 identified by glimmer; putative YP_002451399.1 identified by glimmer; putative YP_002451401.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002451402.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002451403.1 identified by match to protein family HMM PF03417 YP_002451404.1 identified by glimmer; putative YP_002451405.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002451406.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002451407.1 identified by match to protein family HMM PF00583 YP_002451408.1 identified by match to protein family HMM PF07081 YP_002451409.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002451410.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002451411.1 identified by match to protein family HMM PF01520 YP_002451412.1 identified by match to protein family HMM PF01810 YP_002451413.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002451415.1 identified by match to protein family HMM PF01391 YP_002451417.1 identified by match to protein family HMM PF01391 YP_002451419.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824 YP_002451420.1 identified by glimmer; putative YP_002451421.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593 YP_002451422.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002451423.1 identified by glimmer; putative YP_002451424.1 identified by match to protein family HMM PF01596 YP_002451425.1 identified by match to protein family HMM PF05816 YP_002451426.1 identified by glimmer; putative YP_002451427.1 identified by match to protein family HMM PF02638 YP_002451428.1 identified by glimmer; putative YP_002451429.1 identified by match to protein family HMM PF02302 YP_002451430.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002451432.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002451433.1 identified by match to protein family HMM PF01869 YP_002451434.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002451435.1 identified by match to protein family HMM PF00266 YP_002451436.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002451437.1 identified by match to protein family HMM PF06803 YP_002451438.1 identified by match to protein family HMM PF09346 YP_002451439.1 identified by glimmer; putative YP_002451440.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451441.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451443.1 identified by match to protein family HMM PF00753 YP_002451444.1 identified by glimmer; putative YP_002451445.1 identified by glimmer; putative YP_002451446.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002451447.1 identified by glimmer; putative YP_002451448.1 identified by glimmer; putative YP_002451450.1 identified by match to protein family HMM PF00440 YP_002451451.1 identified by match to protein family HMM PF07690 YP_002451452.1 identified by match to protein family HMM PF02687 YP_002451453.1 identified by match to protein family HMM PF00005 YP_002451454.1 identified by match to protein family HMM PF03848; match to protein family HMM PF05724; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451455.1 identified by match to protein family HMM PF06983 YP_002451457.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776 YP_002451458.1 identified by match to protein family HMM PF01047 YP_002451459.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002451460.1 identified by glimmer; putative YP_002451461.1 identified by glimmer; putative YP_002451462.1 identified by glimmer; putative YP_002451463.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002451464.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_002451465.1 identified by glimmer; putative YP_002451466.1 identified by match to protein family HMM PF00657 YP_002451467.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002451468.1 identified by glimmer; putative YP_002451469.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002451470.1 identified by glimmer; putative YP_002451471.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002451472.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00144 YP_002451473.1 identified by match to protein family HMM PF01569 YP_002451474.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002451475.1 identified by match to protein family HMM PF07690 YP_002451476.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002451477.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451478.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451479.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722 YP_002451480.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776 YP_002451481.1 identified by match to protein family HMM PF01261 YP_002451482.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002451483.1 identified by match to protein family HMM PF06845 YP_002451484.1 identified by glimmer; putative YP_002451486.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002451489.1 identified by match to protein family HMM PF01381 YP_002451491.1 identified by match to protein family HMM PF02557 YP_002451492.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002451493.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01520 YP_002451494.1 identified by match to protein family HMM PF07968; match to protein family HMM TIGR01002 YP_002451495.1 identified by match to protein family HMM PF00440 YP_002451496.1 identified by match to protein family HMM PF00005 YP_002451497.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002451498.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002451501.1 identified by match to protein family HMM PF07992 YP_002451502.1 identified by match to protein family HMM PF00581; match to protein family HMM PF00753 YP_002451504.1 identified by glimmer; putative YP_002451505.1 identified by match to protein family HMM PF00005 YP_002451506.1 identified by match to protein family HMM PF01061 YP_002451507.1 identified by match to protein family HMM PF00440 YP_002451508.1 identified by glimmer; putative YP_002451509.1 identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_002451510.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002451511.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002451512.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002451513.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_002451514.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002451515.1 identified by match to protein family HMM PF01039 YP_002451516.1 identified by match to protein family HMM PF00501 YP_002451517.1 identified by glimmer; putative YP_002451518.1 identified by match to protein family HMM PF00583 YP_002451519.1 identified by glimmer; putative YP_002451521.1 identified by match to protein family HMM PF05163 YP_002451522.1 identified by match to protein family HMM PF00768 YP_002451523.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002451524.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002451525.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488 YP_002451526.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451527.1 Enables the cleavage of the glycosidic bond in S-adenosylhomocysteine YP_002451529.1 identified by match to protein family HMM PF00583 YP_002451530.1 identified by glimmer; putative YP_002451531.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504; match to protein family HMM PF07523; match to protein family HMM TIGR01167 YP_002451534.1 identified by match to protein family HMM PF08327 YP_002451535.1 identified by match to protein family HMM PF03551 YP_002451537.1 identified by match to protein family HMM PF00144 YP_002451538.1 identified by match to protein family HMM PF00376; match to protein family HMM PF06445 YP_002451539.1 identified by match to protein family HMM PF07690 YP_002451541.1 identified by match to protein family HMM PF08241 YP_002451543.1 identified by match to protein family HMM PF01636 YP_002451544.1 identified by match to protein family HMM PF01636 YP_002451546.1 identified by match to protein family HMM PF01432; match to protein family HMM TIGR02289 YP_002451547.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451548.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451549.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002451552.1 identified by glimmer; putative YP_002451553.1 identified by glimmer; putative YP_002451554.1 identified by glimmer; putative YP_002451555.1 identified by glimmer; putative YP_002451556.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002451557.1 identified by glimmer; putative YP_002451558.1 identified by match to protein family HMM PF05724; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451559.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01085 YP_002451560.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451561.1 identified by glimmer; putative YP_002451562.1 identified by match to protein family HMM PF07486 YP_002451563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF03069 YP_002451564.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002451565.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02518 YP_002451567.1 identified by match to protein family HMM PF00005 YP_002451568.1 identified by match to protein family HMM PF00583 YP_002451569.1 identified by glimmer; putative YP_002451570.1 identified by match to protein family HMM PF00005 YP_002451571.1 identified by match to protein family HMM PF02687 YP_002451573.1 identified by glimmer; putative YP_002451575.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002451576.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002451577.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002451578.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03070 YP_002451579.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002451580.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002451582.1 identified by glimmer; putative YP_002451583.1 identified by glimmer; putative YP_002451585.1 identified by glimmer; putative YP_002451586.1 identified by glimmer; putative YP_002451588.1 identified by glimmer; putative YP_002451591.1 identified by glimmer; putative YP_002451592.1 identified by glimmer; putative YP_002451593.1 identified by match to protein family HMM PF08874 YP_002451594.1 identified by glimmer; putative YP_002451595.1 identified by match to protein family HMM PF00067 YP_002451596.1 identified by match to protein family HMM PF07690 YP_002451597.1 identified by match to protein family HMM PF00132 YP_002451598.1 identified by match to protein family HMM PF07561 YP_002451599.1 identified by match to protein family HMM PF03551 YP_002451600.1 identified by match to protein family HMM PF00067 YP_002451601.1 identified by match to protein family HMM PF05995 YP_002451602.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002451603.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002451604.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002451605.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002451606.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002451607.1 identified by match to protein family HMM PF07155 YP_002451608.1 identified by match to protein family HMM PF00005 YP_002451609.1 identified by match to protein family HMM PF02361 YP_002451610.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002451611.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF07694 YP_002451613.1 identified by match to protein family HMM PF04229 YP_002451614.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002451615.1 identified by match to protein family HMM PF01569 YP_002451616.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002451617.1 identified by match to protein family HMM PF07690 YP_002451618.1 identified by match to protein family HMM PF00144 YP_002451619.1 identified by match to protein family HMM PF00583 YP_002451621.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002451622.1 identified by match to protein family HMM PF01965 YP_002451623.1 identified by match to protein family HMM PF08279 YP_002451624.1 identified by match to protein family HMM PF01965 YP_002451625.1 identified by match to protein family HMM PF06161 YP_002451626.1 identified by glimmer; putative YP_002451627.1 identified by match to protein family HMM PF00144 YP_002451628.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03966; match to protein family HMM PF08241 YP_002451629.1 identified by match to protein family HMM PF07690 YP_002451630.1 identified by glimmer; putative YP_002451631.1 identified by match to protein family HMM PF00583 YP_002451632.1 identified by match to protein family HMM PF03009 YP_002451635.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002451636.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00892 YP_002451637.1 identified by match to protein family HMM PF01270 YP_002451638.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002451639.1 identified by match to protein family HMM PF00583 YP_002451641.1 identified by match to protein family HMM PF00293 YP_002451642.1 identified by glimmer; putative YP_002451643.1 identified by match to protein family HMM PF00144 YP_002451644.1 identified by glimmer; putative YP_002451645.1 identified by match to protein family HMM PF07690 YP_002451646.1 identified by match to protein family HMM PF03596 YP_002451647.1 identified by match to protein family HMM PF00583 YP_002451648.1 identified by match to protein family HMM PF00293 YP_002451649.1 binds the polymerase to DNA and acts as a sliding clamp YP_002451650.1 identified by match to protein family HMM PF00293 YP_002451651.1 identified by glimmer; putative YP_002451652.1 identified by match to protein family HMM PF00561 YP_002451655.1 identified by glimmer; putative YP_002451656.1 identified by match to protein family HMM PF01042 YP_002451657.1 identified by match to protein family HMM PF09234 YP_002451658.1 identified by match to protein family HMM PF00756; match to protein family HMM PF09350 YP_002451659.1 identified by glimmer; putative YP_002451661.1 identified by match to protein family HMM PF01734 YP_002451662.1 identified by match to protein family HMM PF08000 YP_002451663.1 identified by match to protein family HMM PF00583 YP_002451665.1 identified by match to protein family HMM PF00583 YP_002451667.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002451668.1 identified by glimmer; putative YP_002451669.1 identified by match to protein family HMM PF01541 YP_002451673.1 identified by glimmer; putative YP_002451674.1 identified by glimmer; putative YP_002451676.1 identified by glimmer; putative YP_002451677.1 identified by match to protein family HMM PF00293 YP_002451678.1 identified by match to protein family HMM PF01266 YP_002451680.1 identified by match to protein family HMM PF00797 YP_002451681.1 identified by match to protein family HMM PF08877 YP_002451683.1 identified by match to protein family HMM PF07859 YP_002451684.1 identified by match to protein family HMM PF00282; match to protein family HMM PF01212 YP_002451685.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08415; match to protein family HMM TIGR01733 YP_002451687.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00128; match to protein family HMM PF02806; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM TIGR02104 YP_002451688.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002451690.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance YP_002451691.1 identified by match to protein family HMM PF06445 YP_002451692.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002451693.1 identified by glimmer; putative YP_002451694.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_002451695.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002451696.1 identified by match to protein family HMM PF00561 YP_002451697.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451698.1 identified by glimmer; putative YP_002451699.1 identified by glimmer; putative YP_002451700.1 identified by match to protein family HMM PF08002 YP_002451701.1 identified by match to protein family HMM PF06081 YP_002451702.1 identified by match to protein family HMM PF00583 YP_002451704.1 identified by match to protein family HMM PF09580; match to protein family HMM TIGR02898 YP_002451705.1 identified by match to protein family HMM PF03413; match to protein family HMM TIGR02889 YP_002451706.1 identified by match to protein family HMM PF01471; match to protein family HMM PF07486; match to protein family HMM TIGR02869 YP_002451708.1 identified by match to protein family HMM PF00144 YP_002451709.1 identified by match to protein family HMM PF03301; match to protein family HMM TIGR03036 YP_002451710.1 identified by match to protein family HMM PF04199; match to protein family HMM TIGR03035 YP_002451711.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01814 YP_002451712.1 identified by match to protein family HMM PF00440 YP_002451713.1 identified by match to protein family HMM PF00293 YP_002451714.1 identified by match to protein family HMM PF00797 YP_002451716.1 identified by glimmer; putative YP_002451717.1 identified by glimmer; putative YP_002451718.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002451719.1 identified by glimmer; putative YP_002451720.1 identified by glimmer; putative YP_002451721.1 identified by match to protein family HMM PF00583 YP_002451722.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002451724.1 identified by glimmer; putative YP_002451725.1 identified by glimmer; putative YP_002451726.1 E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002451727.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00198 YP_002451728.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00364 YP_002451729.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002451730.1 identified by match to protein family HMM PF00676 YP_002451732.1 identified by glimmer; putative YP_002451733.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002451734.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF04229 YP_002451737.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002451739.1 identified by glimmer; putative YP_002451740.1 identified by match to protein family HMM PF01230 YP_002451741.1 identified by glimmer; putative YP_002451742.1 identified by match to protein family HMM PF00528 YP_002451743.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186 YP_002451744.1 identified by match to protein family HMM PF04069 YP_002451745.1 identified by match to protein family HMM PF00574; match to protein family HMM TIGR00493 YP_002451746.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002451747.1 identified by match to protein family HMM PF00111 YP_002451748.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002451749.1 identified by match to protein family HMM PF00583 YP_002451750.1 identified by match to protein family HMM PF00041; match to protein family HMM PF02839; match to protein family HMM PF03067 YP_002451751.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002451752.1 identified by match to protein family HMM PF03781 YP_002451753.1 In Listeria monocytogenes this protein binds a specific sites on DNA, influencing the topology and transcription; regulates flaA, proU and ompC; is osmoregulated YP_002451756.1 identified by match to protein family HMM PF01209; match to protein family HMM PF02353; match to protein family HMM PF05401; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451758.1 identified by match to protein family HMM PF08874 YP_002451759.1 identified by match to protein family HMM PF04237 YP_002451760.1 identified by match to protein family HMM PF00583 YP_002451761.1 identified by match to protein family HMM PF00395; match to protein family HMM PF00753 YP_002451763.1 identified by match to protein family HMM PF01183 YP_002451764.1 identified by match to protein family HMM PF00583 YP_002451765.1 identified by glimmer; putative YP_002451766.1 identified by glimmer; putative YP_002451767.1 identified by match to protein family HMM PF00583 YP_002451769.1 identified by match to protein family HMM PF03551 YP_002451770.1 identified by match to protein family HMM PF06108 YP_002451772.1 identified by match to protein family HMM PF02517 YP_002451773.1 identified by match to protein family HMM PF08241 YP_002451774.1 identified by match to protein family HMM PF06094 YP_002451775.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389 YP_002451776.1 identified by glimmer; putative YP_002451778.1 identified by glimmer; putative YP_002451781.1 identified by match to protein family HMM PF01432; match to protein family HMM TIGR02289 YP_002451782.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002451783.1 identified by match to protein family HMM PF03067 YP_002451784.1 identified by match to protein family HMM PF00583 YP_002451785.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002451786.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002451787.1 identified by match to protein family HMM PF00171 YP_002451788.1 identified by match to protein family HMM PF00701; match to protein family HMM TIGR00674 YP_002451789.1 identified by glimmer; putative YP_002451790.1 identified by match to protein family HMM PF05544 YP_002451791.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01266 YP_002451792.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR00229 YP_002451793.1 identified by glimmer; putative YP_002451794.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00111 YP_002451795.1 identified by match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002451797.1 identified by glimmer; putative YP_002451798.1 identified by match to protein family HMM PF08876 YP_002451799.1 identified by match to protein family HMM PF09335 YP_002451801.1 identified by glimmer; putative YP_002451802.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002451803.1 identified by match to protein family HMM PF00583 YP_002451804.1 identified by match to protein family HMM PF00496 YP_002451805.1 identified by match to protein family HMM PF00877 YP_002451806.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002451808.1 identified by match to protein family HMM PF04977 YP_002451809.1 identified by glimmer; putative YP_002451810.1 identified by match to protein family HMM PF00383 YP_002451812.1 identified by glimmer; putative YP_002451813.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451814.1 identified by glimmer; putative YP_002451815.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_002451816.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002451817.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002451818.1 identified by glimmer; putative YP_002451819.1 identified by match to protein family HMM PF00583 YP_002451821.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00702 YP_002451822.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002451823.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002451824.1 identified by match to protein family HMM PF01432 YP_002451826.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002451827.1 identified by match to protein family HMM PF00583 YP_002451829.1 identified by glimmer; putative YP_002451830.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002451832.1 identified by match to protein family HMM PF04519 YP_002451834.1 identified by match to protein family HMM PF00496 YP_002451835.1 identified by match to protein family HMM PF07690 YP_002451838.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451839.1 identified by glimmer; putative YP_002451840.1 identified by match to protein family HMM PF04226 YP_002451841.1 identified by match to protein family HMM PF01156 YP_002451842.1 identified by glimmer; putative YP_002451843.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002451844.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002451845.1 identified by glimmer; putative YP_002451846.1 identified by glimmer; putative YP_002451847.1 identified by match to protein family HMM PF07690 YP_002451848.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002451850.1 identified by glimmer; putative YP_002451851.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002451852.1 identified by match to protein family HMM PF07977 YP_002451853.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_002451857.1 identified by match to protein family HMM PF00005 YP_002451858.1 identified by match to protein family HMM PF00392 YP_002451861.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002451862.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002451863.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002451864.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002451865.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002451866.1 identified by match to protein family HMM PF01594 YP_002451867.1 identified by glimmer; putative YP_002451868.1 catalyzes the release of sulfite from alkanesulfonates YP_002451869.1 identified by match to protein family HMM PF00528 YP_002451870.1 identified by match to protein family HMM PF04069; match to protein family HMM PF09084; match to protein family HMM TIGR01728 YP_002451871.1 identified by match to protein family HMM PF00005 YP_002451872.1 identified by glimmer; putative YP_002451873.1 identified by match to protein family HMM PF00440 YP_002451874.1 identified by match to protein family HMM PF04167 YP_002451875.1 identified by match to protein family HMM PF00293 YP_002451877.1 identified by match to protein family HMM PF07719 YP_002451878.1 identified by match to protein family HMM PF04127 YP_002451879.1 identified by match to protein family HMM PF02522 YP_002451881.1 identified by match to protein family HMM PF03738 YP_002451883.1 identified by glimmer; putative YP_002451884.1 identified by match to protein family HMM PF00583 YP_002451887.1 identified by match to protein family HMM PF00583 YP_002451888.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00583 YP_002451889.1 identified by match to protein family HMM PF01909 YP_002451890.1 identified by match to protein family HMM PF06352 YP_002451892.1 identified by glimmer; putative YP_002451893.1 identified by match to protein family HMM PF01522 YP_002451894.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002451895.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03741 YP_002451896.1 identified by match to protein family HMM PF00884 YP_002451897.1 identified by match to protein family HMM PF00005 YP_002451898.1 identified by glimmer; putative YP_002451899.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03176 YP_002451900.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451901.1 identified by match to protein family HMM PF00440 YP_002451902.1 identified by match to protein family HMM PF00583 YP_002451903.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002451904.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_002451905.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002451906.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002451907.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_002451910.1 identified by match to protein family HMM PF00857 YP_002451911.1 identified by match to protein family HMM PF00583 YP_002451912.1 identified by glimmer; putative YP_002451914.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002451915.1 identified by glimmer; putative YP_002451916.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002451917.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002451918.1 identified by glimmer; putative YP_002451920.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002451922.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02653 YP_002451923.1 identified by glimmer; putative YP_002451924.1 identified by match to protein family HMM PF02653 YP_002451925.1 identified by match to protein family HMM PF00005 YP_002451926.1 identified by match to protein family HMM PF04198 YP_002451927.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002451928.1 identified by match to protein family HMM PF07883 YP_002451929.1 identified by match to protein family HMM PF01791 YP_002451930.1 identified by match to protein family HMM PF00583 YP_002451933.1 identified by match to protein family HMM PF03992 YP_002451934.1 identified by match to protein family HMM PF07690 YP_002451935.1 identified by match to protein family HMM PF01022 YP_002451937.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM TIGR00804 YP_002451938.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002451939.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002451940.1 identified by glimmer; putative YP_002451941.1 identified by match to protein family HMM PF03807 YP_002451942.1 identified by match to protein family HMM PF09234 YP_002451944.1 identified by match to protein family HMM PF01546 YP_002451945.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002451946.1 identified by match to protein family HMM PF00324 YP_002451947.1 identified by match to protein family HMM PF01139 YP_002451948.1 identified by match to protein family HMM PF00487 YP_002451949.1 identified by match to protein family HMM PF00245 YP_002451956.1 identified by match to protein family HMM PF04397 YP_002451957.1 Phosphoprylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway YP_002451958.1 identified by match to protein family HMM PF00583 YP_002451959.1 identified by match to protein family HMM PF00903 YP_002451962.1 identified by glimmer; putative YP_002451963.1 identified by match to protein family HMM PF03551 YP_002451964.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002451965.1 identified by match to protein family HMM PF01882 YP_002451967.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002451968.1 identified by match to protein family HMM PF00535 YP_002451969.1 identified by glimmer; putative YP_002451970.1 identified by match to protein family HMM PF00535 YP_002451971.1 identified by match to protein family HMM PF00535 YP_002451972.1 identified by match to protein family HMM PF02012 YP_002451973.1 identified by match to protein family HMM PF00202 YP_002451974.1 identified by match to protein family HMM PF00199 YP_002451976.1 identified by match to protein family HMM PF01979 YP_002451977.1 identified by match to protein family HMM PF00144 YP_002451978.1 identified by glimmer; putative YP_002451979.1 identified by match to protein family HMM PF09346 YP_002451980.1 identified by match to protein family HMM PF03992 YP_002451981.1 identified by match to protein family HMM PF00881 YP_002451982.1 identified by match to protein family HMM PF01047 YP_002451983.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM PF08477; match to protein family HMM TIGR00231 YP_002451984.1 identified by match to protein family HMM PF07883 YP_002451986.1 identified by match to protein family HMM PF01557 YP_002451987.1 identified by glimmer; putative YP_002451988.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494 YP_002451989.1 identified by match to protein family HMM PF03061 YP_002451990.1 identified by match to protein family HMM PF00501 YP_002451991.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002451992.1 identified by match to protein family HMM PF00378 YP_002451993.1 identified by match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737 YP_002451994.1 identified by match to protein family HMM PF00232 YP_002451995.1 identified by match to protein family HMM PF02255 YP_002451996.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002451997.1 identified by match to protein family HMM PF00300 YP_002451998.1 identified by match to protein family HMM PF02230 YP_002451999.1 identified by match to protein family HMM PF02302 YP_002452000.1 identified by match to protein family HMM PF00376 YP_002452002.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002452003.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002452004.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452005.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452006.1 identified by match to protein family HMM PF00293 YP_002452007.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002452008.1 identified by glimmer; putative YP_002452009.1 identified by glimmer; putative YP_002452011.1 identified by match to protein family HMM PF00005 YP_002452012.1 identified by match to protein family HMM PF00392 YP_002452013.1 identified by match to protein family HMM PF01370 YP_002452014.1 identified by match to protein family HMM PF00005 YP_002452015.1 identified by match to protein family HMM PF02687 YP_002452016.1 identified by match to protein family HMM PF02687 YP_002452017.1 identified by glimmer; putative YP_002452018.1 identified by match to protein family HMM PF00144 YP_002452019.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002452020.1 identified by match to protein family HMM PF00583 YP_002452021.1 identified by glimmer; putative YP_002452022.1 identified by match to protein family HMM PF00293 YP_002452023.1 identified by match to protein family HMM PF00892 YP_002452024.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002452025.1 identified by match to protein family HMM PF02639 YP_002452027.1 identified by glimmer; putative YP_002452029.1 phosphorylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway YP_002452030.1 identified by match to protein family HMM PF00149 YP_002452031.1 identified by match to protein family HMM PF01636 YP_002452033.1 identified by match to protein family HMM PF01925 YP_002452034.1 identified by match to protein family HMM PF00583 YP_002452035.1 identified by match to protein family HMM PF00324 YP_002452039.1 identified by match to protein family HMM PF08241 YP_002452040.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00293 YP_002452041.1 identified by match to protein family HMM PF04989 YP_002452042.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002452043.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002452044.1 identified by glimmer; putative YP_002452045.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002452046.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002452047.1 identified by match to protein family HMM TIGR01765; match to protein family HMM TIGR01766 YP_002452048.1 identified by match to protein family HMM PF06166 YP_002452049.1 identified by match to protein family HMM PF06149 YP_002452050.1 identified by match to protein family HMM PF03746 YP_002452051.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_002452052.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_002452053.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002452054.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002452055.1 identified by match to protein family HMM PF03932 YP_002452056.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867 YP_002452057.1 identified by match to protein family HMM PF01022 YP_002452058.1 identified by glimmer; putative YP_002452059.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028 YP_002452060.1 identified by match to protein family HMM PF02698 YP_002452061.1 identified by match to protein family HMM PF00583 YP_002452062.1 identified by glimmer; putative YP_002452063.1 identified by match to protein family HMM PF07670 YP_002452064.1 identified by match to protein family HMM PF01636 YP_002452065.1 identified by match to protein family HMM PF00583 YP_002452067.1 identified by match to protein family HMM PF01061 YP_002452068.1 identified by match to protein family HMM PF00440 YP_002452069.1 identified by match to protein family HMM PF00391; match to protein family HMM PF01326 YP_002452070.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452071.1 identified by match to protein family HMM PF00753 YP_002452072.1 identified by match to protein family HMM PF09678 YP_002452074.1 identified by match to protein family HMM PF07875 YP_002452075.1 identified by match to protein family HMM PF08892 YP_002452076.1 identified by match to protein family HMM PF01810 YP_002452077.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002452078.1 identified by glimmer; putative YP_002452079.1 identified by match to protein family HMM PF00269 YP_002452082.1 identified by match to protein family HMM PF00269 YP_002452083.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002452084.1 identified by match to protein family HMM PF05067 YP_002452085.1 catalyzes the formation of fumarate from aspartate YP_002452086.1 identified by match to protein family HMM PF00710; match to protein family HMM TIGR00519 YP_002452087.1 identified by match to protein family HMM PF01381 YP_002452089.1 identified by glimmer; putative YP_002452090.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002452091.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002452092.1 identified by match to protein family HMM PF03323 YP_002452093.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002452094.1 identified by match to protein family HMM PF05791 YP_002452095.1 identified by match to protein family HMM PF05791 YP_002452096.1 identified by match to protein family HMM PF05791 YP_002452097.1 identified by match to protein family HMM PF05791 YP_002452098.1 identified by match to protein family HMM PF00165 YP_002452099.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452100.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00269 YP_002452102.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002452103.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002452104.1 identified by match to protein family HMM PF03807 YP_002452105.1 identified by glimmer; putative YP_002452108.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002452109.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002452110.1 identified by match to protein family HMM PF03323 YP_002452111.1 identified by glimmer; putative YP_002452112.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08664 YP_002452113.1 identified by match to protein family HMM PF02518 YP_002452114.1 catalyzes the formation of glutamate from glutamine YP_002452115.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002452116.1 identified by match to protein family HMM PF03600 YP_002452119.1 identified by glimmer; putative YP_002452120.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002452121.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002452122.1 identified by match to protein family HMM PF00199 YP_002452123.1 identified by match to protein family HMM PF00561 YP_002452124.1 identified by match to protein family HMM PF00857 YP_002452125.1 identified by match to protein family HMM PF00857 YP_002452127.1 identified by match to protein family HMM PF07969 YP_002452128.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452129.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002452130.1 identified by match to protein family HMM PF01544 YP_002452134.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002452136.1 identified by match to protein family HMM PF03073 YP_002452137.1 identified by match to protein family HMM PF00875; match to protein family HMM PF03441 YP_002452138.1 identified by match to protein family HMM PF00484 YP_002452140.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002452142.1 identified by match to protein family HMM PF00583 YP_002452143.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002452144.1 identified by match to protein family HMM PF00561 YP_002452146.1 identified by glimmer; putative YP_002452150.1 identified by match to protein family HMM PF00485 YP_002452151.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_002452152.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832 YP_002452153.1 identified by match to protein family HMM PF00903 YP_002452154.1 identified by match to protein family HMM PF01022 YP_002452157.1 identified by match to protein family HMM PF04892 YP_002452158.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002452159.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002452160.1 identified by match to protein family HMM PF00583 YP_002452161.1 identified by match to protein family HMM PF00561; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002452162.1 identified by match to protein family HMM PF00440 YP_002452163.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_002452164.1 identified by match to protein family HMM PF01037 YP_002452165.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002452167.1 identified by match to protein family HMM PF00903 YP_002452168.1 identified by glimmer; putative YP_002452171.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02805 YP_002452172.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002452173.1 identified by match to protein family HMM PF00144 YP_002452174.1 identified by glimmer; putative YP_002452176.1 identified by match to protein family HMM PF08803 YP_002452177.1 identified by match to protein family HMM PF07681 YP_002452178.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965 YP_002452179.1 identified by match to protein family HMM PF00067; match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00667 YP_002452180.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; match to protein family HMM TIGR01951 YP_002452181.1 identified by glimmer; putative YP_002452185.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002452186.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002452187.1 identified by glimmer; putative YP_002452190.1 identified by glimmer; putative YP_002452191.1 catalyzes the formation of pyruvate from D-cysteine YP_002452192.1 identified by match to protein family HMM PF00149 YP_002452193.1 identified by match to protein family HMM PF00144 YP_002452195.1 identified by match to protein family HMM TIGR02304 YP_002452196.1 identified by match to protein family HMM PF00753 YP_002452197.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002452198.1 identified by match to protein family HMM PF02655 YP_002452199.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002452200.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027 YP_002452202.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002452203.1 identified by match to protein family HMM PF00005 YP_002452204.1 identified by match to protein family HMM PF02687 YP_002452205.1 identified by match to protein family HMM PF01022 YP_002452207.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002452208.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002452209.1 identified by match to protein family HMM PF02588 YP_002452210.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002452211.1 identified by match to protein family HMM PF02589 YP_002452212.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_002452213.1 identified by match to protein family HMM PF02754 YP_002452214.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452215.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002452216.1 identified by match to protein family HMM PF02016 YP_002452217.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002452218.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452219.1 identified by glimmer; putative YP_002452220.1 identified by match to protein family HMM PF07690 YP_002452221.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002452222.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR01484 YP_002452223.1 identified by match to protein family HMM PF01041; match to protein family HMM PF01212 YP_002452224.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002452225.1 identified by match to protein family HMM PF00515 YP_002452226.1 identified by glimmer; putative YP_002452228.1 identified by glimmer; putative YP_002452229.1 identified by match to protein family HMM PF00817 YP_002452230.1 identified by match to protein family HMM PF08863 YP_002452231.1 identified by glimmer; putative YP_002452232.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; match to protein family HMM PF02743 YP_002452234.1 identified by match to protein family HMM PF00583 YP_002452236.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222 YP_002452237.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_002452238.1 identified by match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_002452239.1 identified by glimmer; putative YP_002452240.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_002452241.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_002452242.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_002452243.1 identified by match to protein family HMM PF00857 YP_002452244.1 identified by match to protein family HMM PF01037 YP_002452245.1 identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845 YP_002452246.1 identified by glimmer; putative YP_002452247.1 identified by match to protein family HMM PF06245 YP_002452248.1 identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826 YP_002452249.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002452250.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452252.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress YP_002452255.1 identified by match to protein family HMM PF07883 YP_002452256.1 identified by match to protein family HMM PF00165 YP_002452257.1 identified by glimmer; putative YP_002452258.1 identified by match to protein family HMM PF01804 YP_002452260.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002452261.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01510; match to protein family HMM PF08239 YP_002452263.1 identified by match to protein family HMM PF06352 YP_002452264.1 identified by glimmer; putative YP_002452265.1 identified by match to protein family HMM PF00395 YP_002452266.1 identified by match to protein family HMM PF00903 YP_002452269.1 identified by match to protein family HMM PF07690 YP_002452270.1 identified by match to protein family HMM PF00561 YP_002452271.1 identified by match to protein family HMM PF01047 YP_002452272.1 identified by match to protein family HMM PF07690 YP_002452273.1 identified by match to protein family HMM PF00144 YP_002452275.1 identified by match to protein family HMM PF00893 YP_002452276.1 identified by match to protein family HMM PF00440 YP_002452277.1 identified by match to protein family HMM PF01289 YP_002452278.1 identified by glimmer; putative YP_002452279.1 identified by match to protein family HMM PF02667 YP_002452280.1 identified by glimmer; putative YP_002452281.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002452282.1 identified by match to protein family HMM PF04434 YP_002452284.1 identified by glimmer; putative YP_002452287.1 identified by match to protein family HMM PF00005 YP_002452288.1 identified by match to protein family HMM PF02361 YP_002452290.1 identified by match to protein family HMM TIGR01167 YP_002452291.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002452292.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03606 YP_002452294.1 identified by match to protein family HMM PF07690 YP_002452295.1 identified by match to protein family HMM PF00440 YP_002452296.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452297.1 identified by match to protein family HMM PF01381 YP_002452298.1 identified by match to protein family HMM PF01230 YP_002452299.1 identified by match to protein family HMM PF00293 YP_002452300.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_002452301.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002452303.1 identified by glimmer; putative YP_002452304.1 identified by match to protein family HMM PF01638 YP_002452305.1 identified by match to protein family HMM PF00881 YP_002452307.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002452309.1 identified by glimmer; putative YP_002452310.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002452312.1 identified by match to protein family HMM PF00005 YP_002452313.1 identified by glimmer; putative YP_002452314.1 identified by glimmer; putative YP_002452315.1 identified by match to protein family HMM PF01381 YP_002452317.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002452318.1 identified by match to protein family HMM PF07853 YP_002452322.1 identified by match to protein family HMM PF00293 YP_002452324.1 identified by match to protein family HMM PF00903 YP_002452325.1 identified by match to protein family HMM PF00480 YP_002452326.1 identified by match to protein family HMM PF07690 YP_002452327.1 identified by match to protein family HMM PF00132 YP_002452328.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002452329.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002452330.1 identified by match to protein family HMM PF01594 YP_002452331.1 identified by match to protein family HMM PF04226 YP_002452332.1 identified by match to protein family HMM PF00583 YP_002452333.1 identified by glimmer; putative YP_002452334.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002452335.1 identified by match to protein family HMM PF07336 YP_002452336.1 identified by match to protein family HMM PF07690 YP_002452337.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002452341.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002452343.1 identified by match to protein family HMM PF00892 YP_002452344.1 identified by match to protein family HMM PF00805 YP_002452345.1 identified by match to protein family HMM PF06906 YP_002452347.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01314 YP_002452348.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002452349.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_002452350.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_002452351.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002452352.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002452355.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03571 YP_002452356.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002452357.1 identified by match to protein family HMM PF00106 YP_002452358.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF07504 YP_002452359.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03272 YP_002452361.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02012 YP_002452363.1 identified by match to protein family HMM PF03928 YP_002452365.1 identified by glimmer; putative YP_002452366.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222 YP_002452368.1 identified by glimmer; putative YP_002452369.1 identified by match to protein family HMM PF02082 YP_002452370.1 identified by glimmer; putative YP_002452372.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002452374.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002452375.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002452376.1 identified by match to protein family HMM PF02353; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002452377.1 identified by match to protein family HMM PF01638 YP_002452378.1 identified by match to protein family HMM PF01638 YP_002452379.1 identified by match to protein family HMM PF00248 YP_002452381.1 identified by match to protein family HMM PF00753 YP_002452384.1 identified by glimmer; putative YP_002452385.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002452386.1 identified by match to protein family HMM PF00583 YP_002452387.1 identified by match to protein family HMM PF00106 YP_002452388.1 identified by match to protein family HMM PF00583 YP_002452389.1 identified by match to protein family HMM PF00501 YP_002452390.1 identified by match to protein family HMM PF02525 YP_002452391.1 identified by match to protein family HMM PF01638 YP_002452392.1 identified by match to protein family HMM PF01022 YP_002452393.1 identified by match to protein family HMM PF00535; match to protein family HMM PF00704; match to protein family HMM PF01522 YP_002452395.1 Heat shock-induced YP_002452396.1 identified by match to protein family HMM PF00535 YP_002452397.1 identified by match to protein family HMM PF02517 YP_002452398.1 identified by match to protein family HMM PF00440 YP_002452399.1 identified by glimmer; putative YP_002452400.1 identified by match to protein family HMM PF06445 YP_002452401.1 identified by match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002452402.1 identified by match to protein family HMM PF05656 YP_002452403.1 identified by match to protein family HMM PF01061 YP_002452404.1 identified by match to protein family HMM PF00005 YP_002452405.1 identified by match to protein family HMM PF06304 YP_002452406.1 identified by match to protein family HMM PF03551 YP_002452407.1 identified by glimmer; putative YP_002452408.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002452409.1 identified by glimmer; putative YP_002452410.1 identified by match to protein family HMM PF00753 YP_002452412.1 identified by match to protein family HMM PF03819 YP_002452415.1 identified by glimmer; putative YP_002452416.1 identified by match to protein family HMM PF00144 YP_002452417.1 identified by glimmer; putative YP_002452418.1 identified by match to protein family HMM PF03486 YP_002452419.1 identified by match to protein family HMM PF00149 YP_002452420.1 identified by match to protein family HMM PF00027 YP_002452421.1 identified by match to protein family HMM PF04657 YP_002452422.1 identified by match to protein family HMM PF04657 YP_002452423.1 identified by glimmer; putative YP_002452424.1 identified by match to protein family HMM PF00753 YP_002452425.1 identified by glimmer; putative YP_002452426.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02817 YP_002452427.1 identified by match to protein family HMM PF00324 YP_002452428.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_002452431.1 identified by glimmer; putative YP_002452432.1 identified by glimmer; putative YP_002452433.1 identified by glimmer; putative YP_002452434.1 identified by match to protein family HMM PF02585 YP_002452435.1 identified by match to protein family HMM PF08830 YP_002452436.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002452437.1 identified by glimmer; putative YP_002452438.1 identified by match to protein family HMM PF00583 YP_002452439.1 identified by match to protein family HMM PF01497 YP_002452440.1 identified by match to protein family HMM PF01032 YP_002452441.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01032 YP_002452442.1 identified by match to protein family HMM PF05675 YP_002452443.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002452446.1 identified by match to protein family HMM PF05163 YP_002452447.1 identified by match to protein family HMM PF02517 YP_002452450.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452451.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002452452.1 identified by match to protein family HMM PF00300 YP_002452453.1 identified by match to protein family HMM PF00583 YP_002452454.1 identified by match to protein family HMM PF00488 YP_002452456.1 identified by glimmer; putative YP_002452458.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002452459.1 identified by match to protein family HMM PF00797 YP_002452460.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002452461.1 identified by match to protein family HMM PF00144 YP_002452463.1 identified by match to protein family HMM PF07690 YP_002452464.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452465.1 identified by glimmer; putative YP_002452466.1 identified by match to protein family HMM PF02698 YP_002452467.1 identified by match to protein family HMM PF03009 YP_002452468.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002452470.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494 YP_002452471.1 identified by match to protein family HMM PF01022 YP_002452472.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002452473.1 identified by match to protein family HMM PF02696 YP_002452474.1 identified by match to protein family HMM PF00515 YP_002452475.1 identified by glimmer; putative YP_002452476.1 identified by match to protein family HMM PF04299 YP_002452477.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF04229 YP_002452479.1 identified by match to protein family HMM PF01758 YP_002452480.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002452482.1 identified by match to protein family HMM PF00534 YP_002452483.1 identified by match to protein family HMM TIGR01444 YP_002452484.1 identified by match to protein family HMM PF00132 YP_002452485.1 identified by match to protein family HMM PF01041 YP_002452486.1 identified by match to protein family HMM PF00535; match to protein family HMM PF08241 YP_002452487.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002452488.1 identified by match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453 YP_002452489.1 identified by match to protein family HMM PF02308 YP_002452490.1 identified by match to protein family HMM PF00583 YP_002452491.1 identified by match to protein family HMM PF00903 YP_002452492.1 identified by match to protein family HMM PF04294 YP_002452495.1 identified by glimmer; putative YP_002452497.1 has 3'-5' exonuclease activity YP_002452498.1 identified by match to protein family HMM PF00313 YP_002452500.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002452502.1 identified by match to protein family HMM PF00293 YP_002452503.1 identified by match to protein family HMM PF04266 YP_002452504.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451 YP_002452505.1 identified by match to protein family HMM PF00106 YP_002452506.1 identified by match to protein family HMM PF00583 YP_002452507.1 catalyzes the formation of arginine and fumarate from arginosuccinate YP_002452508.1 identified by glimmer; putative YP_002452509.1 identified by match to protein family HMM PF01156 YP_002452510.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002452511.1 identified by match to protein family HMM PF06196 YP_002452512.1 identified by match to protein family HMM PF00171 YP_002452513.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002452514.1 identified by glimmer; putative YP_002452515.1 identified by match to protein family HMM PF00432; match to protein family HMM TIGR01787 YP_002452516.1 identified by match to protein family HMM PF02681 YP_002452517.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002452518.1 identified by match to protein family HMM PF06961 YP_002452519.1 identified by glimmer; putative YP_002452521.1 identified by match to protein family HMM PF01883 YP_002452522.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002452523.1 identified by match to protein family HMM PF02391 YP_002452524.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002452525.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002452526.1 identified by match to protein family HMM PF01226 YP_002452527.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002452528.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002452530.1 identified by match to protein family HMM PF07849 YP_002452531.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_002452532.1 identified by match to protein family HMM PF03323 YP_002452533.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002452534.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002452535.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002452536.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative YP_002452537.1 identified by glimmer; putative YP_002452538.1 identified by glimmer; putative YP_002452540.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00115 YP_002452541.1 identified by match to protein family HMM PF00496 YP_002452542.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01527 YP_002452543.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002452544.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00665 YP_002452545.1 identified by match to protein family HMM PF00496 YP_002452546.1 identified by match to protein family HMM PF00496 YP_002452547.1 involved in the transport of C4-dicarboxylates across the membrane YP_002452548.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002452549.1 identified by glimmer; putative YP_002452550.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002452551.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002452552.1 identified by match to protein family HMM PF00903 YP_002452554.1 identified by match to protein family HMM PF00005 YP_002452555.1 identified by match to protein family HMM PF00440 YP_002452556.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_002452557.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002452558.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002452559.1 identified by glimmer; putative YP_002452560.1 identified by match to protein family HMM PF02629 YP_002452561.1 identified by match to protein family HMM PF00089 YP_002452562.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002452563.1 identified by match to protein family HMM TIGR02491 YP_002452564.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002452565.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002452566.1 identified by match to protein family HMM PF01521 YP_002452567.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_002452568.1 identified by match to protein family HMM PF00704; match to protein family HMM PF01476 YP_002452569.1 identified by match to protein family HMM TIGR03090 YP_002452570.1 SASP N; found in forespore compartment YP_002452572.1 3'-5' exonuclease of DNA polymerase III YP_002452573.1 identified by glimmer; putative YP_002452574.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002452575.1 identified by glimmer; putative YP_002452576.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002452577.1 Catalyzes the conversion of citrate to isocitrate YP_002452578.1 SASP O; found in forespore compartment YP_002452579.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02764 YP_002452581.1 SASP P; found in forespore compartment YP_002452585.1 identified by match to protein family HMM PF02272; match to protein family HMM PF07973 YP_002452586.1 identified by match to protein family HMM PF00293 YP_002452587.1 identified by glimmer; putative YP_002452588.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002452589.1 activates fatty acids by binding to coenzyme A YP_002452590.1 identified by match to protein family HMM PF02632 YP_002452591.1 identified by match to protein family HMM PF00501 YP_002452593.1 identified by glimmer; putative YP_002452594.1 identified by match to protein family HMM PF05532 YP_002452595.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00395 YP_002452596.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002452598.1 identified by match to protein family HMM PF01510 YP_002452599.1 identified by glimmer; putative YP_002452600.1 identified by match to protein family HMM PF02588 YP_002452601.1 identified by match to protein family HMM PF00903 YP_002452602.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002452603.1 identified by match to protein family HMM PF02230 YP_002452604.1 identified by match to protein family HMM PF00903 YP_002452605.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002452606.1 identified by match to protein family HMM PF01645 YP_002452607.1 identified by match to protein family HMM PF00724 YP_002452608.1 identified by match to protein family HMM PF02559 YP_002452609.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002452610.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002452611.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002452612.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002452613.1 regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure YP_002452614.1 identified by match to protein family HMM PF01965 YP_002452616.1 identified by glimmer; putative YP_002452618.1 identified by glimmer; putative YP_002452624.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451 YP_002452625.1 similar to pXO1-23; this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00078; match to protein family HMM PF01844 YP_002452626.1 identified by glimmer; putative YP_002452627.1 identified by glimmer; putative YP_002452628.1 identified by match to protein family HMM PF07301 YP_002452629.1 identified by match to protein family HMM PF02683 YP_002452630.1 identified by match to protein family HMM PF00892 YP_002452631.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002452633.1 identified by match to protein family HMM PF00005 YP_002452635.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452636.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002452637.1 identified by match to protein family HMM PF04172 YP_002452638.1 identified by match to protein family HMM PF00293 YP_002452639.1 identified by glimmer; putative YP_002452640.1 identified by match to protein family HMM PF01925 YP_002452641.1 identified by glimmer; putative YP_002452642.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01510 YP_002452643.1 identified by glimmer; putative YP_002452645.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002452646.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002452647.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03672 YP_002452648.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002452649.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002452650.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002452651.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_002452652.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_002452653.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_002452654.1 identified by match to protein family HMM TIGR01098 YP_002452655.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002452656.1 identified by match to protein family HMM PF05979 YP_002452657.1 identified by match to protein family HMM PF00239 YP_002452658.1 Represses a number of genes involved in the response to DNA damage YP_002452660.1 identified by match to protein family HMM PF08006 YP_002452661.1 identified by match to protein family HMM PF03551 YP_002452662.1 identified by glimmer; putative YP_002452663.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_002452664.1 identified by match to protein family HMM PF00376 YP_002452665.1 identified by match to protein family HMM PF01053; match to protein family HMM PF06838 YP_002452666.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR03156 YP_002452667.1 identified by match to protein family HMM PF03458 YP_002452669.1 identified by match to protein family HMM PF00004; match to protein family HMM TIGR02881 YP_002452670.1 identified by match to protein family HMM PF02899 YP_002452671.1 identified by match to protein family HMM PF01391 YP_002452672.1 Stimulates the elongation of poly(A) tails YP_002452673.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002452674.1 identified by glimmer; putative YP_002452675.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002452676.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427 YP_002452677.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002452678.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002452679.1 identified by match to protein family HMM PF00465 YP_002452680.1 identified by match to protein family HMM PF04238 YP_002452682.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002452683.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452684.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00324 YP_002452685.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00704 YP_002452686.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002452687.1 identified by glimmer; putative YP_002452688.1 identified by match to protein family HMM PF00149 YP_002452689.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_002452690.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00216 YP_002452691.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002452692.1 identified by match to protein family HMM PF00403; match to protein family HMM TIGR00003 YP_002452693.1 identified by match to protein family HMM PF02583 YP_002452695.1 identified by match to protein family HMM PF00756 YP_002452696.1 identified by match to protein family HMM PF00005 YP_002452697.1 identified by match to protein family HMM PF01032 YP_002452698.1 identified by match to protein family HMM PF01032 YP_002452699.1 identified by match to protein family HMM PF01497 YP_002452700.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633 YP_002452701.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02805 YP_002452702.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002452703.1 identified by match to protein family HMM PF00730; match to protein family HMM PF07934 YP_002452704.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002452705.1 identified by match to protein family HMM PF02588 YP_002452706.1 identified by glimmer; putative YP_002452707.1 identified by glimmer; putative YP_002452708.1 identified by match to protein family HMM PF00300 YP_002452709.1 identified by match to protein family HMM PF00561 YP_002452710.1 identified by match to protein family HMM PF00903 YP_002452711.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002452713.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452715.1 identified by match to protein family HMM PF04172 YP_002452716.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002452717.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002452718.1 identified by match to protein family HMM PF00561 YP_002452719.1 identified by match to protein family HMM PF02585 YP_002452720.1 identified by glimmer; putative YP_002452721.1 identified by match to protein family HMM PF00388 YP_002452722.1 identified by glimmer; putative YP_002452723.1 identified by match to protein family HMM PF00082; match to protein family HMM PF04151 YP_002452724.1 identified by match to protein family HMM PF01476; match to protein family HMM PF07486 YP_002452726.1 identified by match to protein family HMM PF00884 YP_002452729.1 identified by match to protein family HMM PF02275 YP_002452730.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002452731.1 This protein performs the mismatch recognition step during the DNA repair process YP_002452734.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002452735.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_002452736.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02780 YP_002452737.1 identified by match to protein family HMM PF01244 YP_002452738.1 identified by match to protein family HMM PF04232 YP_002452739.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00282 YP_002452740.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_002452741.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00154 YP_002452742.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00154 YP_002452743.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00177; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200 YP_002452744.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002452745.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002452748.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002452749.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002452750.1 identified by match to protein family HMM PF05193 YP_002452751.1 identified by match to protein family HMM PF02653 YP_002452752.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02653 YP_002452753.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00005 YP_002452754.1 identified by match to protein family HMM PF02608 YP_002452755.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002452756.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397 YP_002452758.1 identified by match to protein family HMM PF00574 YP_002452759.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002452760.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002452761.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive YP_002452762.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002452763.1 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme YP_002452764.1 catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance YP_002452765.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888 YP_002452766.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002452767.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02873 YP_002452768.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591 YP_002452769.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002452770.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002452771.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002452772.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002452773.1 identified by match to protein family HMM PF04456 YP_002452774.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002452775.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00009; match to protein family HMM PF01926; match to protein family HMM PF04760; match to protein family HMM TIGR00231 YP_002452776.1 identified by match to protein family HMM PF01248 YP_002452777.1 identified by match to protein family HMM PF04296 YP_002452778.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002452779.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002452780.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_002452781.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002452782.1 identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054 YP_002452783.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002452784.1 identified by match to protein family HMM PF01148 YP_002452785.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002452786.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002452787.1 Catalyzes the phosphorylation of UMP to UDP YP_002452788.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002452789.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002452790.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_002452791.1 heat shock protein involved in degradation of misfolded proteins YP_002452792.1 heat shock protein involved in degradation of misfolded proteins YP_002452793.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002452794.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_002452795.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002452796.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002452797.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002452798.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00549 YP_002452799.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08442 YP_002452800.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002452801.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_002452802.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002452803.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002452804.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002452805.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF05239; match to protein family HMM TIGR02273 YP_002452806.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01782 YP_002452808.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002452809.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959 YP_002452810.1 identified by match to protein family HMM PF04297; match to protein family HMM PF08281 YP_002452811.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064 YP_002452812.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR00650; match to protein family HMM TIGR02168 YP_002452813.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002452814.1 carries the fatty acid chain in fatty acid biosynthesis YP_002452815.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002452816.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002452817.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002452818.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_002452819.1 catalyzes branch migration in Holliday junction intermediates YP_002452820.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02734; match to protein family HMM TIGR03599 YP_002452821.1 identified by match to protein family HMM PF03780 YP_002452822.1 required for 70S ribosome assembly YP_002452823.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378 YP_002452824.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002452825.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002452826.1 identified by match to protein family HMM PF00069; match to protein family HMM PF03793; match to protein family HMM PF07714 YP_002452827.1 identified by match to protein family HMM PF00481 YP_002452828.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002452829.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563 YP_002452830.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002452831.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002452832.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002452833.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002452834.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002452835.1 Essential for recycling GMP and indirectly, cGMP YP_002452836.1 identified by match to protein family HMM PF04025 YP_002452837.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_002452838.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002452839.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833 YP_002452840.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002452846.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002452847.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002452848.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_002452849.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_002452850.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002452851.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002452852.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002452853.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002452854.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002452855.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_002452856.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005 YP_002452857.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002452859.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002452860.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544 YP_002452861.1 identified by match to protein family HMM PF01479 YP_002452862.1 identified by match to protein family HMM PF02325 YP_002452863.1 identified by match to protein family HMM PF04472 YP_002452864.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_002452865.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_002452866.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888 YP_002452867.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin YP_002452868.1 identified by glimmer; putative YP_002452869.1 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation YP_002452870.1 identified by match to protein family HMM PF03419; match to protein family HMM TIGR02854 YP_002452871.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002452872.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174 YP_002452873.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478 YP_002452874.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002452875.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002452876.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615 YP_002452877.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002452878.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002452879.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002452880.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; match to protein family HMM TIGR02214 YP_002452881.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002452882.1 identified by match to protein family HMM PF04977; match to protein family HMM TIGR02209 YP_002452883.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002452885.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002452886.1 identified by match to protein family HMM PF00583 YP_002452887.1 identified by match to protein family HMM PF00249; match to protein family HMM TIGR02894 YP_002452888.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002452889.1 identified by match to protein family HMM PF02620 YP_002452890.1 identified by match to protein family HMM PF05636 YP_002452891.1 identified by match to protein family HMM PF05362 YP_002452892.1 identified by match to protein family HMM PF01734 YP_002452893.1 identified by match to protein family HMM PF07670; match to protein family HMM TIGR02871 YP_002452894.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002452895.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095 YP_002452898.1 identified by match to protein family HMM PF07050 YP_002452899.1 identified by match to protein family HMM PF00300 YP_002452902.1 identified by match to protein family HMM PF00188 YP_002452903.1 identified by match to protein family HMM PF08868 YP_002452904.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate YP_002452905.1 identified by match to protein family HMM PF09678; match to protein family HMM TIGR02737 YP_002452906.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02908 YP_002452907.1 identified by match to protein family HMM PF00510 YP_002452908.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02891 YP_002452909.1 identified by match to protein family HMM PF00034; match to protein family HMM PF00116; match to protein family HMM PF02790; match to protein family HMM TIGR02866 YP_002452910.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002452911.1 identified by match to protein family HMM PF02628 YP_002452912.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_002452913.1 identified by match to protein family HMM PF01098 YP_002452914.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; putative ligand binding protein YP_002452916.1 identified by match to protein family HMM PF02562 YP_002452917.1 identified by match to protein family HMM PF01243 YP_002452919.1 identified by glimmer; putative YP_002452921.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF08477; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002452922.1 identified by glimmer; putative YP_002452923.1 identified by match to protein family HMM PF00459 YP_002452925.1 identified by match to protein family HMM PF06335 YP_002452926.1 identified by match to protein family HMM PF05256 YP_002452927.1 identified by match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002452928.1 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links YP_002452929.1 identified by glimmer; putative YP_002452931.1 identified by glimmer; putative YP_002452933.1 identified by glimmer; putative YP_002452934.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002452935.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 YP_002452936.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002452937.1 identified by match to protein family HMM PF00676; match to protein family HMM TIGR03181 YP_002452938.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002452939.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002452940.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002452941.1 identified by match to protein family HMM PF07288 YP_002452942.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002452943.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254 YP_002452945.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002452946.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; match to protein family HMM TIGR03532 YP_002452947.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002452948.1 identified by match to protein family HMM PF00571 YP_002452950.1 identified by match to protein family HMM PF04308 YP_002452951.1 identified by glimmer; putative YP_002452952.1 identified by match to protein family HMM PF08796 YP_002452953.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02196 YP_002452954.1 identified by glimmer; putative YP_002452956.1 identified by match to protein family HMM PF00563 YP_002452957.1 identified by match to protein family HMM PF00106 YP_002452958.1 identified by match to protein family HMM PF00149 YP_002452959.1 identified by glimmer; putative YP_002452960.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002452961.1 identified by match to protein family HMM PF02541 YP_002452964.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002452966.1 identified by glimmer; putative YP_002452967.1 identified by glimmer; putative YP_002452968.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002452969.1 identified by match to protein family HMM PF03551 YP_002452970.1 identified by match to protein family HMM PF00293 YP_002452971.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002452975.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002452976.1 identified by glimmer; putative YP_002452977.1 identified by match to protein family HMM PF00155 YP_002452978.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002452979.1 identified by glimmer; putative YP_002452980.1 identified by match to protein family HMM PF00528 YP_002452981.1 identified by match to protein family HMM PF00528 YP_002452982.1 identified by match to protein family HMM PF01547 YP_002452983.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903 YP_002452984.1 identified by match to protein family HMM PF00128 YP_002452985.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002452986.1 identified by match to protein family HMM PF00106 YP_002452987.1 identified by glimmer; putative YP_002452988.1 identified by match to protein family HMM PF06271 YP_002452992.1 identified by match to protein family HMM PF02463 YP_002452993.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002452994.1 identified by match to protein family HMM PF00293 YP_002452995.1 identified by glimmer; putative YP_002452996.1 identified by glimmer; putative YP_002453000.1 identified by match to protein family HMM PF03551 YP_002453001.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_002453003.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_002453004.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002453005.1 identified by match to protein family HMM PF00795 YP_002453006.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however YP_002453007.1 converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage YP_002453008.1 converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage YP_002453009.1 converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage YP_002453010.1 identified by match to protein family HMM PF03079; match to protein family HMM PF07883 YP_002453011.1 identified by glimmer; putative YP_002453012.1 identified by glimmer; putative YP_002453013.1 identified by match to protein family HMM PF03446 YP_002453014.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002453015.1 identified by match to protein family HMM PF00881 YP_002453016.1 identified by glimmer; putative YP_002453017.1 identified by glimmer; putative YP_002453018.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002453019.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002453020.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02002 YP_002453021.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002453022.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002453023.1 identified by match to protein family HMM PF07702 YP_002453024.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002453025.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR00221 YP_002453026.1 identified by match to protein family HMM PF00753 YP_002453027.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer YP_002453028.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_002453029.1 identified by match to protein family HMM PF03745 YP_002453030.1 identified by match to protein family HMM PF00583 YP_002453031.1 identified by glimmer; putative YP_002453032.1 identified by match to protein family HMM PF00160 YP_002453033.1 identified by match to protein family HMM PF06207 YP_002453034.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002453035.1 identified by match to protein family HMM PF03323 YP_002453037.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839 YP_002453038.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845 YP_002453039.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838 YP_002453042.1 identified by glimmer; putative YP_002453043.1 identified by match to protein family HMM PF00209 YP_002453044.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. YP_002453045.1 binds to sigma F preventing its association with RNA polymerase during sporulation YP_002453046.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; match to protein family HMM TIGR02886 YP_002453047.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002453048.1 identified by match to protein family HMM PF00392; match to protein family HMM PF02082 YP_002453049.1 identified by match to protein family HMM PF00005 YP_002453052.1 identified by glimmer; putative YP_002453053.1 identified by glimmer; putative YP_002453054.1 identified by match to protein family HMM PF01047 YP_002453055.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002453056.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04402 YP_002453057.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002453058.1 identified by match to protein family HMM PF01544; match to protein family HMM TIGR00383 YP_002453059.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002453060.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002453061.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002453063.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002453065.1 identified by match to protein family HMM PF01475 YP_002453066.1 identified by match to protein family HMM PF01944; match to protein family HMM TIGR02831 YP_002453067.1 identified by match to protein family HMM PF00583 YP_002453068.1 identified by match to protein family HMM PF00293 YP_002453069.1 identified by glimmer; putative YP_002453070.1 identified by match to protein family HMM PF00248 YP_002453071.1 identified by match to protein family HMM PF00248 YP_002453072.1 identified by match to protein family HMM PF04229 YP_002453074.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002453076.1 identified by match to protein family HMM PF00561 YP_002453077.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002453078.1 identified by match to protein family HMM PF00356 YP_002453079.1 identified by match to protein family HMM PF00583 YP_002453082.1 identified by match to protein family HMM PF09360 YP_002453083.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_002453084.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002453085.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_002453086.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002453088.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_002453089.1 identified by match to protein family HMM PF05401; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR02072 YP_002453090.1 identified by match to protein family HMM PF00561 YP_002453091.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002453092.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002453093.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002453094.1 identified by glimmer; putative YP_002453095.1 identified by glimmer; putative YP_002453096.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002453097.1 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002453098.1 identified by match to protein family HMM PF00657 YP_002453099.1 identified by match to protein family HMM PF01047 YP_002453101.1 identified by glimmer; putative YP_002453102.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_002453103.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707 YP_002453104.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002453105.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_002453106.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002453107.1 identified by glimmer; putative YP_002453108.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002453109.1 identified by match to protein family HMM PF00753 YP_002453110.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002453111.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_002453112.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_002453113.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002453114.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002453115.1 identified by glimmer; putative YP_002453116.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002453117.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01883 YP_002453118.1 identified by match to protein family HMM PF00583 YP_002453119.1 identified by glimmer; putative YP_002453120.1 identified by match to protein family HMM PF03734 YP_002453121.1 identified by match to protein family HMM PF06081 YP_002453122.1 identified by match to protein family HMM PF00005 YP_002453123.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002453124.1 identified by match to protein family HMM PF00497; match to protein family HMM PF04069 YP_002453125.1 identified by glimmer; putative YP_002453126.1 identified by match to protein family HMM PF06491 YP_002453128.1 identified by match to protein family HMM PF00293 YP_002453129.1 identified by match to protein family HMM PF01098 YP_002453130.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 YP_002453131.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002453132.1 identified by match to protein family HMM PF00676 YP_002453133.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002453134.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate YP_002453135.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002453136.1 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate YP_002453137.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF02954; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002453139.1 identified by match to protein family HMM PF03009 YP_002453142.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08769; match to protein family HMM TIGR02875 YP_002453143.1 identified by match to protein family HMM PF00595; match to protein family HMM PF05580; match to protein family HMM TIGR02860 YP_002453144.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002453145.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002453146.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478 YP_002453147.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002453148.1 identified by match to protein family HMM PF00348 YP_002453149.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002453150.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002453151.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002453152.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002453153.1 identified by match to protein family HMM PF03780 YP_002453154.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002453155.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002453157.1 identified by match to protein family HMM TIGR02830 YP_002453158.1 identified by match to protein family HMM PF09581; match to protein family HMM TIGR02896 YP_002453159.1 identified by match to protein family HMM PF09546; match to protein family HMM TIGR02829 YP_002453160.1 identified by match to protein family HMM PF09555; match to protein family HMM TIGR02849 YP_002453161.1 identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848 YP_002453162.1 necessary for complete engulfment of forespore YP_002453163.1 identified by match to protein family HMM TIGR02858 YP_002453166.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002453167.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002453168.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002453169.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002453171.1 identified by match to protein family HMM PF07136 YP_002453173.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002453174.1 involved in manganese homeostasis; activates the transcription of the mntABCD operon YP_002453175.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00620 YP_002453177.1 identified by glimmer; putative YP_002453178.1 identified by match to protein family HMM PF03099 YP_002453179.1 identified by match to protein family HMM PF00581 YP_002453180.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002453181.1 identified by match to protein family HMM PF00440 YP_002453182.1 identified by match to protein family HMM PF00893 YP_002453183.1 identified by match to protein family HMM PF00893 YP_002453184.1 identified by glimmer; putative YP_002453185.1 identified by glimmer; putative YP_002453191.1 identified by match to protein family HMM PF00005 YP_002453192.1 identified by match to protein family HMM PF00392 YP_002453195.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_002453196.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_002453197.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002453198.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002453200.1 identified by glimmer; putative YP_002453201.1 identified by glimmer; putative YP_002453205.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002453206.1 identified by glimmer; putative YP_002453207.1 identified by match to protein family HMM PF03171 YP_002453210.1 identified by glimmer; putative YP_002453211.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002453212.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002453213.1 identified by match to protein family HMM PF00482 YP_002453214.1 identified by match to protein family HMM PF00437 YP_002453217.1 identified by match to protein family HMM PF00375 YP_002453218.1 identified by glimmer; putative YP_002453220.1 identified by glimmer; putative YP_002453221.1 identified by glimmer; putative YP_002453222.1 identified by glimmer; putative YP_002453223.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002453224.1 identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607; match to protein family HMM PF02965; match to protein family HMM TIGR02082 YP_002453225.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_002453226.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity YP_002453227.1 catalyzes the formation of L-homocysteine from cystathionine YP_002453228.1 identified by match to protein family HMM PF00857 YP_002453229.1 identified by match to protein family HMM PF01022 YP_002453230.1 identified by match to protein family HMM PF02636 YP_002453231.1 identified by match to protein family HMM PF00753 YP_002453233.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744 YP_002453234.1 identified by match to protein family HMM PF06014 YP_002453235.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727 YP_002453236.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002453237.1 identified by match to protein family HMM PF00132; match to protein family HMM PF00483; match to protein family HMM PF02878 YP_002453238.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002453239.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002453240.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002453241.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002453242.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM TIGR02136 YP_002453243.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002453244.1 identified by match to protein family HMM PF07690 YP_002453245.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002453246.1 identified by glimmer; putative YP_002453247.1 identified by match to protein family HMM PF06691 YP_002453249.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002453250.1 identified by match to protein family HMM PF01475 YP_002453251.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032 YP_002453252.1 identified by match to protein family HMM PF00005 YP_002453253.1 identified by match to protein family HMM PF02588 YP_002453255.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002453256.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002453257.1 identified by glimmer; putative YP_002453259.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002453260.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002453261.1 identified by match to protein family HMM PF04816 YP_002453262.1 identified by match to protein family HMM PF00034 YP_002453263.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_002453264.1 synthesizes RNA primers at the replication forks YP_002453265.1 identified by glimmer; putative YP_002453266.1 identified by glimmer; putative YP_002453267.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF03618 YP_002453268.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00571; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002453269.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002453271.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002453272.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002453273.1 identified by match to protein family HMM PF01219 YP_002453274.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002453275.1 identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277 YP_002453276.1 identified by match to protein family HMM PF02562 YP_002453277.1 identified by match to protein family HMM PF06898; match to protein family HMM TIGR02876 YP_002453278.1 identified by match to protein family HMM PF07241; match to protein family HMM TIGR02856 YP_002453279.1 identified by match to protein family HMM PF09424 YP_002453280.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002453281.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579 YP_002453282.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002453283.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002453284.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002453285.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002453286.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002453287.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_002453288.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002453289.1 identified by match to protein family HMM PF01638 YP_002453290.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002453292.1 Initiates the rapid degradation of small, acid-soluble proteins during spore germination YP_002453293.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002453294.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002453296.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002453297.1 identified by match to protein family HMM PF00383; match to protein family HMM TIGR02571 YP_002453298.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426 YP_002453299.1 may be involved in regulation of competence genes YP_002453300.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002453301.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002453302.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488 YP_002453303.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002453304.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253 YP_002453305.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002453306.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_002453307.1 identified by match to protein family HMM PF09419; match to protein family HMM TIGR01662; match to protein family HMM TIGR01668 YP_002453308.1 identified by match to protein family HMM PF08970 YP_002453309.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002453310.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281 YP_002453311.1 identified by match to protein family HMM PF01726 YP_002453312.1 identified by glimmer; putative YP_002453313.1 identified by match to protein family HMM PF01183; match to protein family HMM PF08460 YP_002453315.1 identified by match to protein family HMM PF00589 YP_002453316.1 identified by glimmer; putative YP_002453317.1 identified by match to protein family HMM PF09693; match to protein family HMM TIGR01669 YP_002453318.1 identified by glimmer; putative YP_002453319.1 identified by glimmer; putative YP_002453320.1 identified by glimmer; putative YP_002453321.1 identified by match to protein family HMM TIGR01665 YP_002453322.1 identified by match to protein family HMM PF06997 YP_002453323.1 identified by match to protein family HMM TIGR01760 YP_002453326.1 identified by match to protein family HMM TIGR01603 YP_002453328.1 identified by match to protein family HMM TIGR01725 YP_002453329.1 identified by match to protein family HMM PF06264; match to protein family HMM TIGR01563 YP_002453330.1 identified by match to protein family HMM TIGR01560 YP_002453331.1 identified by match to protein family HMM PF05065 YP_002453332.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_002453333.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002453334.1 identified by match to protein family HMM PF03354 YP_002453335.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558 YP_002453336.1 identified by glimmer; putative YP_002453337.1 identified by match to protein family HMM PF01844 YP_002453339.1 identified by glimmer; putative YP_002453340.1 identified by glimmer; putative YP_002453341.1 identified by match to protein family HMM PF00589 YP_002453342.1 identified by match to protein family HMM TIGR01637 YP_002453344.1 identified by glimmer; putative YP_002453345.1 identified by glimmer; putative YP_002453346.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002453347.1 identified by glimmer; putative YP_002453348.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002453350.1 identified by glimmer; putative YP_002453351.1 identified by glimmer; putative YP_002453352.1 identified by glimmer; putative YP_002453355.1 identified by glimmer; putative YP_002453356.1 unwinds double stranded DNA YP_002453357.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002453358.1 identified by glimmer; putative YP_002453359.1 identified by glimmer; putative YP_002453360.1 identified by glimmer; putative YP_002453361.1 identified by glimmer; putative YP_002453362.1 identified by match to protein family HMM PF01381 YP_002453363.1 identified by match to protein family HMM PF01381 YP_002453364.1 identified by match to protein family HMM PF06114 YP_002453366.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002453367.1 identified by match to protein family HMM PF04542 YP_002453369.1 identified by match to protein family HMM PF03413 YP_002453370.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002453371.1 identified by match to protein family HMM PF00881 YP_002453372.1 identified by glimmer; putative YP_002453373.1 identified by match to protein family HMM PF04607 YP_002453375.1 identified by match to protein family HMM PF00245 YP_002453377.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00583 YP_002453378.1 identified by match to protein family HMM PF00561 YP_002453379.1 identified by match to protein family HMM PF04173; match to protein family HMM PF07681 YP_002453381.1 identified by match to protein family HMM PF00300 YP_002453382.1 identified by glimmer; putative YP_002453383.1 identified by glimmer; putative YP_002453385.1 identified by match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF05922 YP_002453387.1 phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_002453388.1 identified by match to protein family HMM PF01329 YP_002453389.1 identified by match to protein family HMM PF00903 YP_002453390.1 identified by match to protein family HMM PF07681 YP_002453391.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002453392.1 identified by match to protein family HMM PF01575 YP_002453393.1 identified by match to protein family HMM PF00583 YP_002453394.1 identified by match to protein family HMM PF00583 YP_002453396.1 identified by match to protein family HMM PF00005 YP_002453397.1 identified by match to protein family HMM PF01032 YP_002453398.1 identified by match to protein family HMM PF01497 YP_002453400.1 identified by match to protein family HMM PF00465 YP_002453401.1 catalyzes the formation of L-homocysteine from cystathionine YP_002453402.1 identified by match to protein family HMM PF00291 YP_002453403.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002453404.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002453406.1 identified by match to protein family HMM PF07423 YP_002453407.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002453408.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002453409.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002453410.1 identified by match to protein family HMM PF01136 YP_002453411.1 identified by match to protein family HMM PF01136 YP_002453412.1 identified by match to protein family HMM PF01596; match to protein family HMM PF02390 YP_002453413.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002453414.1 identified by match to protein family HMM PF06949 YP_002453415.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002453416.1 identified by match to protein family HMM PF06135 YP_002453417.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002453419.1 identified by match to protein family HMM PF01594 YP_002453420.1 identified by glimmer; putative YP_002453421.1 identified by glimmer; putative YP_002453423.1 identified by match to protein family HMM TIGR01448 YP_002453424.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002453425.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002453426.1 identified by match to protein family HMM PF00266 YP_002453427.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738 YP_002453428.1 identified by match to protein family HMM PF00004 YP_002453429.1 identified by match to protein family HMM TIGR02894 YP_002453430.1 identified by match to protein family HMM PF00899 YP_002453431.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002453432.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002453435.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002453436.1 identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002453437.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002453438.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002453439.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002453440.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002453442.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; match to protein family HMM TIGR02900 YP_002453443.1 identified by match to protein family HMM PF04239 YP_002453445.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002453446.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002453447.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002453449.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF01330; match to protein family HMM PF05491; match to protein family HMM PF05496; match to protein family HMM PF07499; match to protein family HMM PF07728; match to protein family HMM TIGR00084; match to protein family HMM TIGR00635 YP_002453450.1 identified by match to protein family HMM PF01497 YP_002453451.1 identified by match to protein family HMM PF08955; match to protein family HMM PF08977 YP_002453452.1 identified by match to protein family HMM PF00892 YP_002453453.1 identified by match to protein family HMM PF01022; match to protein family HMM PF08279 YP_002453454.1 identified by glimmer; putative YP_002453455.1 identified by match to protein family HMM PF09580 YP_002453456.1 identified by match to protein family HMM PF01476; match to protein family HMM TIGR02899 YP_002453457.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002453458.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002453459.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002453460.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002453461.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279 YP_002453462.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002453463.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002453464.1 identified by match to protein family HMM PF02687 YP_002453465.1 identified by match to protein family HMM PF02687 YP_002453466.1 identified by match to protein family HMM PF00005 YP_002453467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002453468.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453469.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002453471.1 involved in the peptidyltransferase reaction during translation YP_002453472.1 identified by match to protein family HMM PF04327 YP_002453473.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002453474.1 identified by match to protein family HMM TIGR00757 YP_002453475.1 identified by match to protein family HMM PF02163 YP_002453476.1 identified by match to protein family HMM PF01551 YP_002453477.1 identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968 YP_002453478.1 blocks the formation of polar Z-ring septums YP_002453479.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426 YP_002453480.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002453481.1 functions in MreBCD complex in some organisms YP_002453482.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR02053 YP_002453486.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02051 YP_002453488.1 identified by match to protein family HMM PF00589 YP_002453489.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002453490.1 identified by match to protein family HMM PF00633; match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_002453491.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002453493.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002453494.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002453495.1 identified by match to protein family HMM TIGR02904 YP_002453496.1 identified by match to protein family HMM PF01476; match to protein family HMM TIGR02907 YP_002453497.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002453498.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002453499.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002453500.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002453501.1 identified by match to protein family HMM PF01578 YP_002453502.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002453503.1 identified by match to protein family HMM PF01047 YP_002453504.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03561 YP_002453505.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002453506.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_002453507.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF05362; match to protein family HMM TIGR02902 YP_002453508.1 binds and unfolds substrates as part of the ClpXP protease YP_002453509.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002453511.1 identified by glimmer; putative YP_002453512.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002453514.1 identified by glimmer; putative YP_002453515.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002453516.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_002453517.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002453519.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002453520.1 identified by match to protein family HMM PF07690 YP_002453521.1 identified by glimmer; putative YP_002453522.1 identified by match to protein family HMM PF01965 YP_002453523.1 identified by match to protein family HMM PF00440 YP_002453524.1 identified by match to protein family HMM PF01965 YP_002453525.1 identified by glimmer; putative YP_002453528.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002453529.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00362 YP_002453532.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002453533.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002453535.1 identified by match to protein family HMM PF01381 YP_002453536.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002453538.1 identified by match to protein family HMM PF01381 YP_002453547.1 identified by match to protein family HMM PF06114 YP_002453548.1 identified by glimmer; putative YP_002453549.1 identified by glimmer; putative YP_002453550.1 identified by match to protein family HMM PF00860 YP_002453551.1 identified by match to protein family HMM PF00892 YP_002453552.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_002453553.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_002453554.1 identified by match to protein family HMM PF00496 YP_002453555.1 identified by match to protein family HMM PF00528 YP_002453556.1 identified by match to protein family HMM PF00528 YP_002453557.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002453558.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002453559.1 identified by match to protein family HMM PF06580 YP_002453560.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_002453562.1 identified by match to protein family HMM PF04024 YP_002453563.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002453565.1 identified by match to protein family HMM PF00230 YP_002453566.1 identified by match to protein family HMM PF02082 YP_002453568.1 identified by match to protein family HMM PF00005 YP_002453569.1 identified by match to protein family HMM PF03767; match to protein family HMM TIGR01533 YP_002453570.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002453571.1 With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_002453572.1 identified by match to protein family HMM PF02557 YP_002453573.1 identified by match to protein family HMM PF03061 YP_002453574.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002453575.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002453576.1 identified by match to protein family HMM TIGR02046 YP_002453578.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002453579.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002453580.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012 YP_002453581.1 identified by match to protein family HMM PF01012 YP_002453582.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002453583.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08359 YP_002453584.1 activates fatty acids by binding to coenzyme A YP_002453585.1 identified by match to protein family HMM PF01391 YP_002453586.1 identified by glimmer; putative YP_002453587.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01497 YP_002453588.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002453589.1 identified by match to protein family HMM PF05163 YP_002453593.1 identified by glimmer; putative YP_002453594.1 identified by match to protein family HMM PF00005 YP_002453595.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002453596.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453597.1 identified by glimmer; putative YP_002453600.1 identified by match to protein family HMM PF00999 YP_002453602.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_002453603.1 identified by match to protein family HMM PF07170; match to protein family HMM TIGR03064 YP_002453604.1 identified by match to protein family HMM PF00005 YP_002453605.1 identified by match to protein family HMM PF01032 YP_002453606.1 identified by match to protein family HMM PF01497 YP_002453607.1 identified by match to protein family HMM PF05031; match to protein family HMM TIGR03063 YP_002453608.1 identified by match to protein family HMM PF05031; match to protein family HMM TIGR03063 YP_002453609.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002453610.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002453611.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_002453612.1 identified by match to protein family HMM PF02811 YP_002453613.1 identified by match to protein family HMM PF02674 YP_002453614.1 identified by match to protein family HMM PF05164 YP_002453615.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002453616.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01351 YP_002453618.1 identified by glimmer; putative YP_002453619.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002453620.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002453621.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002453622.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002453623.1 identified by match to protein family HMM TIGR03092 YP_002453624.1 identified by match to protein family HMM PF01966 YP_002453625.1 identified by match to protein family HMM PF02517 YP_002453626.1 identified by match to protein family HMM PF02517 YP_002453627.1 identified by glimmer; putative YP_002453628.1 identified by glimmer; putative YP_002453629.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002453631.1 identified by match to protein family HMM PF00440 YP_002453632.1 identified by match to protein family HMM PF05343 YP_002453633.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08761 YP_002453634.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002453635.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002453636.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002453637.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002453638.1 identified by match to protein family HMM PF08812; match to protein family HMM TIGR02834 YP_002453639.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_002453640.1 identified by match to protein family HMM PF07261 YP_002453641.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002453642.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002453643.1 identified by glimmer; putative YP_002453644.1 NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis YP_002453645.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002453646.1 identified by match to protein family HMM PF02659; match to protein family HMM TIGR02840 YP_002453647.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002453648.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002453649.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002453650.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453651.1 identified by glimmer; putative YP_002453652.1 identified by match to protein family HMM PF01575 YP_002453653.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_002453654.1 Converts isocitrate to alpha ketoglutarate YP_002453655.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_002453656.1 identified by match to protein family HMM PF04284 YP_002453657.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01594; match to protein family HMM TIGR02872 YP_002453658.1 identified by match to protein family HMM PF04186 YP_002453659.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002453660.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002453661.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002453662.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002453663.1 identified by match to protein family HMM PF00392 YP_002453664.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949 YP_002453665.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_002453668.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002453671.1 identified by glimmer; putative YP_002453673.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085 YP_002453674.1 identified by glimmer; putative YP_002453675.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_002453676.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002453682.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002453684.1 identified by match to protein family HMM PF00583 YP_002453685.1 identified by match to protein family HMM PF07883 YP_002453687.1 identified by match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF05222; match to protein family HMM TIGR00518 YP_002453688.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002453689.1 identified by match to protein family HMM PF00582 YP_002453693.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002453694.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_002453697.1 identified by match to protein family HMM PF02588 YP_002453699.1 identified by glimmer; putative YP_002453700.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00293 YP_002453701.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002453702.1 identified by match to protein family HMM PF02384 YP_002453703.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002453704.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002453706.1 catalyzes the phosphorylation of NAD to NADP YP_002453707.1 identified by match to protein family HMM PF07969 YP_002453708.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002453709.1 identified by match to protein family HMM PF00501 YP_002453710.1 identified by match to protein family HMM PF00269 YP_002453711.1 Required for the synthesis of the thiazole moiety YP_002453712.1 identified by match to protein family HMM PF00266 YP_002453713.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_002453714.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002453715.1 identified by match to protein family HMM PF00892 YP_002453716.1 identified by match to protein family HMM PF00440 YP_002453717.1 identified by match to protein family HMM PF01590 YP_002453718.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_002453719.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002453720.1 identified by glimmer; putative YP_002453722.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002453723.1 identified by glimmer; putative YP_002453724.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002453726.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002453728.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01842 YP_002453729.1 identified by match to protein family HMM PF00850 YP_002453730.1 identified by match to protein family HMM PF00561 YP_002453731.1 identified by glimmer; putative YP_002453732.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453733.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002453734.1 identified by match to protein family HMM PF00023 YP_002453735.1 identified by match to protein family HMM PF01408 YP_002453736.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002453739.1 identified by glimmer; putative YP_002453741.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481 YP_002453742.1 identified by match to protein family HMM PF07537 YP_002453744.1 identified by match to protein family HMM PF06103 YP_002453745.1 identified by match to protein family HMM PF02073 YP_002453747.1 identified by glimmer; putative YP_002453748.1 identified by match to protein family HMM PF00583 YP_002453749.1 identified by match to protein family HMM PF03551 YP_002453751.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002453752.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002453753.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397 YP_002453754.1 identified by glimmer; putative YP_002453755.1 identified by match to protein family HMM PF01588 YP_002453756.1 identified by match to protein family HMM PF07285 YP_002453757.1 identified by match to protein family HMM PF00085 YP_002453758.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002453759.1 identified by match to protein family HMM PF05343 YP_002453760.1 identified by match to protein family HMM PF03413 YP_002453761.1 identified by match to protein family HMM PF00753 YP_002453762.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002453764.1 identified by match to protein family HMM PF01636; match to protein family HMM PF02958 YP_002453765.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104 YP_002453766.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_002453767.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_002453768.1 identified by match to protein family HMM PF08220 YP_002453769.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002453770.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002453771.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_002453772.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002453773.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002453774.1 identified by match to protein family HMM PF01022 YP_002453775.1 identified by match to protein family HMM PF08327 YP_002453776.1 identified by glimmer; putative YP_002453779.1 identified by match to protein family HMM PF02559 YP_002453780.1 Converts glucose to D-glucono-1,5 lactone YP_002453781.1 identified by match to protein family HMM PF06800; match to protein family HMM TIGR00776 YP_002453782.1 identified by glimmer; putative YP_002453783.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002453784.1 identified by match to protein family HMM PF02391 YP_002453785.1 identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176 YP_002453786.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002453787.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002453788.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002453789.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002453790.1 identified by match to protein family HMM PF01391 YP_002453791.1 identified by glimmer; putative YP_002453793.1 identified by match to protein family HMM PF00581 YP_002453794.1 identified by glimmer; putative YP_002453795.1 catalyzes the formation of O-acetyl -L-homoserine from L-homoserine and acetyl-CoA YP_002453796.1 identified by glimmer; putative YP_002453798.1 identified by match to protein family HMM PF03323 YP_002453799.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002453800.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002453801.1 identified by glimmer; putative YP_002453803.1 identified by glimmer; putative YP_002453804.1 identified by glimmer; putative YP_002453805.1 identified by glimmer; putative YP_002453806.1 identified by glimmer; putative YP_002453807.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002453808.1 identified by match to protein family HMM PF07690 YP_002453809.1 identified by match to protein family HMM PF00999 YP_002453810.1 identified by match to protein family HMM PF02080 YP_002453811.1 identified by match to protein family HMM PF00589 YP_002453812.1 identified by match to protein family HMM PF02687 YP_002453813.1 identified by match to protein family HMM PF00005 YP_002453814.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002453815.1 identified by glimmer; putative YP_002453817.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_002453818.1 identified by match to protein family HMM PF06962 YP_002453819.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002453821.1 identified by match to protein family HMM PF03929 YP_002453822.1 identified by glimmer; putative YP_002453825.1 identified by match to protein family HMM PF00132 YP_002453826.1 identified by match to protein family HMM PF01569 YP_002453827.1 identified by match to protein family HMM PF00534 YP_002453829.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177 YP_002453830.1 identified by glimmer; putative YP_002453832.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002453833.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002453834.1 identified by match to protein family HMM PF05468 YP_002453835.1 identified by glimmer; putative YP_002453836.1 identified by match to protein family HMM PF00892 YP_002453839.1 identified by match to protein family HMM PF01391 YP_002453840.1 identified by match to protein family HMM PF02518 YP_002453841.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002453842.1 identified by match to protein family HMM PF00561 YP_002453843.1 identified by match to protein family HMM PF00884 YP_002453844.1 identified by glimmer; putative YP_002453845.1 identified by glimmer; putative YP_002453847.1 identified by match to protein family HMM PF00005 YP_002453848.1 identified by match to protein family HMM PF00528 YP_002453849.1 identified by glimmer; putative YP_002453850.1 identified by glimmer; putative YP_002453851.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002453853.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR02705 YP_002453855.1 identified by glimmer; putative YP_002453857.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002453858.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_002453859.1 identified by match to protein family HMM PF00484 YP_002453860.1 identified by match to protein family HMM PF01654 YP_002453861.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002453863.1 identified by glimmer; putative YP_002453864.1 identified by match to protein family HMM PF00395; match to protein family HMM PF05901 YP_002453865.1 identified by match to protein family HMM PF02698 YP_002453866.1 identified by match to protein family HMM PF02588 YP_002453867.1 identified by glimmer; putative YP_002453869.1 identified by glimmer; putative YP_002453871.1 identified by match to protein family HMM PF04012 YP_002453873.1 identified by glimmer; putative YP_002453874.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00437 YP_002453875.1 identified by match to protein family HMM PF04023 YP_002453876.1 identified by match to protein family HMM PF09515; match to protein family HMM TIGR02357 YP_002453877.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002453878.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453879.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002453880.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002453881.1 identified by glimmer; putative YP_002453882.1 identified by glimmer; putative YP_002453883.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002453884.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_002453885.1 identified by glimmer; putative YP_002453886.1 identified by match to protein family HMM TIGR01784 YP_002453888.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002453889.1 identified by match to protein family HMM PF09335 YP_002453891.1 identified by match to protein family HMM PF02687 YP_002453892.1 identified by match to protein family HMM PF00005 YP_002453893.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002453894.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453895.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002453896.1 identified by match to protein family HMM PF02687 YP_002453898.1 identified by match to protein family HMM PF00005 YP_002453899.1 identified by match to protein family HMM PF02687 YP_002453900.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002453901.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002453902.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002453903.1 identified by match to protein family HMM PF00294 YP_002453904.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002453905.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002453906.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002453907.1 identified by match to protein family HMM PF02557 YP_002453908.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002453909.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002453910.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; match to protein family HMM TIGR01928 YP_002453911.1 converts O-succinylbenzoate to O-succinylbenzoyl-CoA YP_002453912.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002453913.1 identified by match to protein family HMM PF00561 YP_002453914.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002453915.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002453916.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002453917.1 identified by match to protein family HMM TIGR02890 YP_002453918.1 identified by match to protein family HMM PF00313 YP_002453919.1 identified by match to protein family HMM PF01987; match to protein family HMM TIGR00266 YP_002453920.1 identified by match to protein family HMM PF01764 YP_002453921.1 identified by glimmer; putative YP_002453922.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002453923.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002453924.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR02092 YP_002453925.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002453926.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002453927.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002453928.1 identified by match to protein family HMM PF02308 YP_002453929.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885 YP_002453930.1 identified by match to protein family HMM PF08868 YP_002453931.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002453932.1 identified by match to protein family HMM PF04070 YP_002453933.1 induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation YP_002453934.1 identified by match to protein family HMM PF00155 YP_002453935.1 identified by match to protein family HMM PF01037 YP_002453936.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002453937.1 identified by match to protein family HMM PF00561 YP_002453938.1 identified by match to protein family HMM PF08958 YP_002453939.1 identified by match to protein family HMM PF00155 YP_002453940.1 identified by match to protein family HMM PF00080 YP_002453942.1 identified by match to protein family HMM PF08810 YP_002453943.1 inhibitor of the KinA pathway of sporulation YP_002453944.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002453946.1 identified by match to protein family HMM PF08713 YP_002453947.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002453948.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002453950.1 identified by match to protein family HMM PF02632 YP_002453951.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_002453952.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002453953.1 identified by match to protein family HMM PF02457 YP_002453954.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002453955.1 identified by match to protein family HMM PF06725 YP_002453957.1 identified by match to protein family HMM PF00293 YP_002453958.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002453959.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002453960.1 identified by match to protein family HMM PF00746; match to protein family HMM PF01345; match to protein family HMM TIGR01167; match to protein family HMM TIGR01451 YP_002453961.1 identified by match to protein family HMM PF06445 YP_002453962.1 identified by match to protein family HMM PF07690 YP_002453964.1 identified by match to protein family HMM PF04463 YP_002453965.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002453966.1 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049 YP_002453967.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002453968.1 identified by match to protein family HMM PF07293 YP_002453969.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002453970.1 identified by match to protein family HMM PF09388 YP_002453971.1 identified by match to protein family HMM PF00005 YP_002453972.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_002453973.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002453974.1 identified by glimmer; putative YP_002453975.1 identified by match to protein family HMM PF02517 YP_002453976.1 identified by match to protein family HMM PF01909 YP_002453977.1 identified by match to protein family HMM PF07315 YP_002453978.1 identified by match to protein family HMM PF01106 YP_002453979.1 identified by glimmer; putative YP_002453980.1 identified by match to protein family HMM TIGR02905 YP_002453981.1 identified by match to protein family HMM PF04608 YP_002453982.1 identified by match to protein family HMM PF00583 YP_002453983.1 identified by match to protein family HMM PF02525 YP_002453985.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460 YP_002453986.1 identified by match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002453987.1 identified by match to protein family HMM PF01934 YP_002453988.1 similar to GlpX type II fructose-1,6-bisphosphatase YP_002453991.1 identified by match to protein family HMM PF06265 YP_002453992.1 identified by match to protein family HMM PF09580 YP_002453993.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739; match to protein family HMM PF09278 YP_002453996.1 identified by match to protein family HMM PF00300 YP_002453997.1 identified by match to protein family HMM PF04073 YP_002453998.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002453999.1 identified by match to protein family HMM PF01551 YP_002454000.1 identified by match to protein family HMM PF09560; match to protein family HMM TIGR02832 YP_002454001.1 identified by match to protein family HMM PF08827 YP_002454004.1 identified by match to protein family HMM PF03551 YP_002454005.1 identified by match to protein family HMM PF04892 YP_002454006.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980 YP_002454007.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994 YP_002454008.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979 YP_002454009.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981 YP_002454010.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978 YP_002454011.1 identified by match to protein family HMM PF03180 YP_002454012.1 identified by match to protein family HMM PF03180 YP_002454013.1 identified by match to protein family HMM PF00528 YP_002454014.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002454015.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454016.1 identified by glimmer; putative YP_002454018.1 identified by match to protein family HMM PF01751 YP_002454019.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002454020.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002454021.1 identified by glimmer; putative YP_002454022.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454024.1 identified by glimmer; putative YP_002454028.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002454029.1 identified by match to protein family HMM PF07875 YP_002454031.1 identified by match to protein family HMM PF02517 YP_002454032.1 identified by glimmer; putative YP_002454034.1 identified by match to protein family HMM PF01381 YP_002454035.1 identified by match to protein family HMM PF00440 YP_002454036.1 identified by match to protein family HMM PF00753 YP_002454037.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002454038.1 identified by glimmer; putative YP_002454039.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002454040.1 identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737 YP_002454041.1 identified by glimmer; putative YP_002454042.1 identified by match to protein family HMM PF00768; match to protein family HMM PF00905 YP_002454043.1 identified by match to protein family HMM PF01619 YP_002454045.1 identified by match to protein family HMM PF01910; match to protein family HMM TIGR00106 YP_002454046.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002454047.1 identified by match to protein family HMM PF01978 YP_002454048.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002454049.1 identified by glimmer; putative YP_002454050.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002454051.1 identified by match to protein family HMM PF00324 YP_002454053.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_002454054.1 identified by glimmer; putative YP_002454055.1 identified by match to protein family HMM PF02588 YP_002454056.1 identified by glimmer; putative YP_002454057.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454058.1 identified by glimmer; putative YP_002454060.1 identified by glimmer; putative YP_002454061.1 identified by match to protein family HMM PF01381 YP_002454062.1 identified by glimmer; putative YP_002454063.1 identified by match to protein family HMM PF09335 YP_002454064.1 identified by glimmer; putative YP_002454065.1 identified by match to protein family HMM PF03734 YP_002454066.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002454067.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002454068.1 identified by match to protein family HMM PF00892 YP_002454069.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002454070.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002454071.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002454072.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002454073.1 identified by match to protein family HMM PF01883 YP_002454074.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002454075.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_002454076.1 identified by match to protein family HMM PF01047 YP_002454077.1 identified by glimmer; putative YP_002454078.1 identified by match to protein family HMM PF00999 YP_002454079.1 identified by match to protein family HMM PF02080 YP_002454080.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002454081.1 identified by match to protein family HMM PF00210 YP_002454082.1 identified by glimmer; putative YP_002454083.1 identified by glimmer; putative YP_002454084.1 identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730 YP_002454085.1 identified by match to protein family HMM PF03819 YP_002454086.1 identified by match to protein family HMM PF00210 YP_002454088.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002454089.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002454090.1 identified by glimmer; putative YP_002454091.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002454092.1 identified by match to protein family HMM PF01370 YP_002454096.1 identified by match to protein family HMM PF00248 YP_002454097.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002454098.1 identified by match to protein family HMM PF01638 YP_002454100.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002454101.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002454102.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002454106.1 identified by match to protein family HMM PF00015 YP_002454107.1 identified by match to protein family HMM PF03372 YP_002454108.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002454109.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002454110.1 identified by glimmer; putative YP_002454112.1 identified by match to protein family HMM PF00583 YP_002454113.1 identified by match to protein family HMM PF06146 YP_002454114.1 identified by match to protein family HMM PF08378 YP_002454116.1 identified by match to protein family HMM PF00005 YP_002454117.1 identified by match to protein family HMM PF01032 YP_002454118.1 identified by match to protein family HMM PF01032 YP_002454119.1 identified by match to protein family HMM PF01497 YP_002454120.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002454121.1 identified by match to protein family HMM PF02518 YP_002454122.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002454123.1 identified by match to protein family HMM PF00005 YP_002454124.1 identified by match to protein family HMM PF02687 YP_002454125.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002454126.1 identified by match to protein family HMM PF00005 YP_002454127.1 identified by match to protein family HMM PF02687 YP_002454128.1 identified by glimmer; putative YP_002454129.1 identified by match to protein family HMM TIGR00362 YP_002454132.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002454133.1 identified by match to protein family HMM PF00583 YP_002454134.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002454135.1 identified by glimmer; putative YP_002454136.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063 YP_002454138.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002454139.1 identified by match to protein family HMM PF04172 YP_002454140.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002454141.1 identified by match to protein family HMM PF01156 YP_002454142.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002454143.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002454144.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002454145.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002454146.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002454147.1 identified by match to protein family HMM PF04198 YP_002454148.1 identified by match to protein family HMM PF00462; match to protein family HMM PF05768 YP_002454149.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002454150.1 identified by match to protein family HMM PF07870 YP_002454152.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838 YP_002454153.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845 YP_002454154.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839 YP_002454155.1 identified by match to protein family HMM PF07870 YP_002454156.1 identified by match to protein family HMM PF04239; match to protein family HMM PF07870 YP_002454157.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002454158.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002454159.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647 YP_002454160.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002454161.1 identified by match to protein family HMM PF03668 YP_002454162.1 identified by match to protein family HMM PF00293 YP_002454163.1 identified by match to protein family HMM PF04018 YP_002454164.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292 YP_002454165.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002454166.1 identified by match to protein family HMM PF00132 YP_002454167.1 hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation YP_002454168.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002454169.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_002454170.1 identified by match to protein family HMM PF04020 YP_002454171.1 identified by glimmer; putative YP_002454172.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002454173.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002454176.1 identified by match to protein family HMM PF00376 YP_002454178.1 identified by glimmer; putative YP_002454179.1 identified by glimmer; putative YP_002454180.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454181.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454182.1 identified by match to protein family HMM PF01381 YP_002454183.1 identified by match to protein family HMM PF03601 YP_002454184.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002454185.1 identified by match to protein family HMM PF00376 YP_002454186.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002454187.1 identified by match to protein family HMM PF00005 YP_002454188.1 identified by match to protein family HMM PF01906 YP_002454189.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002454191.1 identified by match to protein family HMM PF00595; match to protein family HMM PF01471; match to protein family HMM PF03572; match to protein family HMM TIGR00225 YP_002454192.1 identified by match to protein family HMM PF02687 YP_002454193.1 identified by match to protein family HMM PF00005 YP_002454195.1 identified by glimmer; putative YP_002454196.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA YP_002454197.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002454198.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741 YP_002454200.1 identified by match to protein family HMM PF00313 YP_002454202.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002454203.1 identified by match to protein family HMM PF00877 YP_002454204.1 identified by match to protein family HMM PF01638 YP_002454205.1 identified by glimmer; putative YP_002454206.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002454207.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002454208.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002454209.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002454210.1 identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002454211.1 identified by match to protein family HMM PF00953 YP_002454212.1 identified by match to protein family HMM PF01522 YP_002454213.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF03610; match to protein family HMM PF07728 YP_002454214.1 identified by match to protein family HMM PF07452 YP_002454215.1 identified by match to protein family HMM PF02417; match to protein family HMM TIGR00937 YP_002454216.1 identified by match to protein family HMM PF04794 YP_002454217.1 identified by match to protein family HMM PF02056 YP_002454218.1 identified by match to protein family HMM PF02255 YP_002454219.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00359; match to protein family HMM TIGR00410 YP_002454220.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454221.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002454222.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002454223.1 identified by match to protein family HMM PF02255 YP_002454224.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00359; match to protein family HMM TIGR00410 YP_002454225.1 identified by match to protein family HMM PF02302; match to protein family HMM TIGR00853 YP_002454226.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00375 YP_002454228.1 identified by match to protein family HMM PF00903 YP_002454229.1 identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002454230.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002454232.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454233.1 identified by match to protein family HMM PF01654 YP_002454235.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002454236.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002454237.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002454240.1 identified by match to protein family HMM PF06803 YP_002454241.1 identified by match to protein family HMM PF00884 YP_002454243.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_002454244.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00877; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002454245.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002454247.1 identified by match to protein family HMM PF00535 YP_002454248.1 identified by glimmer; putative YP_002454249.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842 YP_002454250.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002454251.1 identified by glimmer; putative YP_002454255.1 identified by match to protein family HMM PF04434 YP_002454256.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_002454258.1 identified by match to protein family HMM PF07872 YP_002454259.1 identified by glimmer; putative YP_002454261.1 identified by match to protein family HMM PF06338 YP_002454262.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002454263.1 identified by glimmer; putative YP_002454265.1 identified by match to protein family HMM PF02687 YP_002454266.1 identified by match to protein family HMM PF00005 YP_002454267.1 identified by match to protein family HMM TIGR01730 YP_002454269.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00881 YP_002454272.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002454273.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002454274.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002454275.1 attenuator function for control of operon expression YP_002454276.1 identified by glimmer; putative YP_002454277.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002454279.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002454280.1 with TagG is involved in the export of teichoic acids YP_002454281.1 identified by match to protein family HMM PF01061 YP_002454282.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002454283.1 identified by match to protein family HMM PF07495; match to protein family HMM PF07940 YP_002454284.1 identified by glimmer; putative YP_002454286.1 identified by glimmer; putative YP_002454287.1 identified by match to protein family HMM PF00534 YP_002454288.1 identified by match to protein family HMM PF00534 YP_002454289.1 identified by match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904 YP_002454291.1 identified by match to protein family HMM PF07495 YP_002454292.1 identified by glimmer; putative YP_002454293.1 identified by match to protein family HMM PF01551 YP_002454294.1 identified by match to protein family HMM PF01061 YP_002454295.1 identified by match to protein family HMM PF00005 YP_002454296.1 identified by match to protein family HMM PF00005; match to protein family HMM PF04397 YP_002454297.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870 YP_002454298.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002454299.1 identified by match to protein family HMM PF08680 YP_002454300.1 identified by match to protein family HMM PF06612; match to protein family HMM TIGR02327 YP_002454301.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454302.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454303.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002454304.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454305.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454306.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454307.1 Catalyzes the transfer of electrons from NADH to quinone YP_002454308.1 catalyzes the transfer of electrons from NADH to ubiquinone YP_002454309.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002454310.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002454311.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002454312.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002454313.1 identified by match to protein family HMM PF06161 YP_002454314.1 identified by match to protein family HMM PF06161 YP_002454315.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002454316.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002454317.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002454318.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002454319.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002454320.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002454321.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002454322.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002454323.1 identified by match to protein family HMM PF05468 YP_002454325.1 identified by glimmer; putative YP_002454326.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002454327.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002454328.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440 YP_002454329.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_002454330.1 identified by match to protein family HMM PF01451 YP_002454331.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830 YP_002454332.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF07681 YP_002454333.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002454334.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002454335.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454336.1 identified by match to protein family HMM PF02659 YP_002454337.1 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057 YP_002454339.1 identified by match to protein family HMM PF09551; match to protein family HMM TIGR02837 YP_002454340.1 identified by match to protein family HMM PF01170; match to protein family HMM PF05175; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387; match to protein family HMM TIGR03534 YP_002454341.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002454342.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002454343.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002454344.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002454345.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454346.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002454347.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002454348.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002454349.1 identified by match to protein family HMM PF00072 YP_002454351.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002454352.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_002454353.1 identified by match to protein family HMM PF00440 YP_002454354.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002454355.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002454356.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_002454357.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002454358.1 identified by match to protein family HMM PF02754 YP_002454359.1 identified by match to protein family HMM PF00614 YP_002454360.1 identified by match to protein family HMM PF03851; match to protein family HMM TIGR00629 YP_002454361.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002454362.1 identified by match to protein family HMM PF05968 YP_002454363.1 identified by match to protein family HMM PF01381 YP_002454364.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002454365.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002454366.1 identified by match to protein family HMM PF01061 YP_002454367.1 identified by match to protein family HMM PF00005 YP_002454368.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_002454369.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05737; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002454370.1 identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389 YP_002454371.1 identified by glimmer; putative YP_002454373.1 identified by glimmer; putative YP_002454374.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002454375.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002454376.1 identified by match to protein family HMM PF09148 YP_002454377.1 identified by match to protein family HMM PF02016 YP_002454378.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002454380.1 identified by glimmer; putative YP_002454381.1 identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230 YP_002454382.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002454383.1 identified by match to protein family HMM PF07690 YP_002454384.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278 YP_002454385.1 identified by glimmer; putative YP_002454386.1 identified by match to protein family HMM PF03009 YP_002454387.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002454388.1 identified by match to protein family HMM PF08741 YP_002454389.1 identified by match to protein family HMM PF02163 YP_002454390.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002454391.1 identified by match to protein family HMM PF01966 YP_002454392.1 identified by match to protein family HMM PF01497 YP_002454393.1 identified by match to protein family HMM PF00005 YP_002454394.1 identified by match to protein family HMM PF01032 YP_002454395.1 identified by match to protein family HMM PF01032 YP_002454397.1 identified by match to protein family HMM TIGR02894 YP_002454399.1 identified by match to protein family HMM PF03099 YP_002454401.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002454402.1 identified by glimmer; putative YP_002454403.1 identified by match to protein family HMM PF06778 YP_002454404.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002454405.1 identified by match to protein family HMM PF07486 YP_002454406.1 identified by match to protein family HMM PF09671; match to protein family HMM TIGR02728 YP_002454407.1 identified by match to protein family HMM PF04241 YP_002454409.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; match to protein family HMM PF07885 YP_002454410.1 identified by match to protein family HMM PF00860 YP_002454411.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002454413.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002454415.1 identified by match to protein family HMM PF00005 YP_002454416.1 identified by match to protein family HMM PF00657 YP_002454417.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002454418.1 identified by match to protein family HMM PF02588 YP_002454419.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002454420.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002454421.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_002454422.1 identified by match to protein family HMM PF00654 YP_002454423.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002454424.1 activator of nucleoside metabolism YP_002454425.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002454426.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002454427.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002454428.1 catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine YP_002454429.1 identified by match to protein family HMM PF00990; match to protein family HMM PF07694; match to protein family HMM TIGR00254 YP_002454430.1 identified by match to protein family HMM PF04328 YP_002454431.1 identified by match to protein family HMM PF02554 YP_002454432.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002454433.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002454434.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454435.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002454436.1 identified by match to protein family HMM PF00534 YP_002454438.1 identified by match to protein family HMM PF03458 YP_002454439.1 identified by match to protein family HMM PF00015 YP_002454441.1 identified by match to protein family HMM PF03061 YP_002454442.1 identified by match to protein family HMM PF01943 YP_002454443.1 identified by match to protein family HMM PF00535 YP_002454444.1 identified by match to protein family HMM PF00005 YP_002454447.1 identified by match to protein family HMM PF04138 YP_002454448.1 identified by match to protein family HMM PF00535 YP_002454449.1 identified by match to protein family HMM PF00440 YP_002454450.1 identified by match to protein family HMM PF00873 YP_002454451.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002454452.1 identified by glimmer; putative YP_002454453.1 identified by match to protein family HMM PF01594 YP_002454454.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases YP_002454455.1 negatively regulates murein hydrolase activity YP_002454456.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002454457.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002454458.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002454459.1 identified by match to protein family HMM PF02028 YP_002454460.1 identified by match to protein family HMM PF02898 YP_002454461.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002454462.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002454463.1 identified by match to protein family HMM PF02293 YP_002454464.1 identified by glimmer; putative YP_002454465.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002454466.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002454467.1 identified by match to protein family HMM PF08876 YP_002454468.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880 YP_002454469.1 identified by match to protein family HMM PF01757 YP_002454470.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306 YP_002454471.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002454472.1 identified by match to protein family HMM PF04055 YP_002454473.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002454474.1 identified by match to protein family HMM PF01541 YP_002454475.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002454478.1 identified by match to protein family HMM PF02486 YP_002454479.1 identified by glimmer; putative YP_002454480.1 identified by glimmer; putative YP_002454481.1 identified by match to protein family HMM PF00656 YP_002454482.1 identified by glimmer; putative YP_002454483.1 identified by match to protein family HMM PF04055 YP_002454484.1 identified by match to protein family HMM PF02223 YP_002454485.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002454487.1 identified by match to protein family HMM PF00089 YP_002454488.1 identified by match to protein family HMM PF00753 YP_002454489.1 identified by match to protein family HMM PF09648 YP_002454490.1 identified by match to protein family HMM PF07435 YP_002454491.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002454492.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002454493.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002454494.1 unwinds double stranded DNA YP_002454495.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002454496.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002454497.1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error YP_002454498.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002454499.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002454500.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002454501.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002454502.1 identified by match to protein family HMM PF06107 YP_002454503.1 identified by match to protein family HMM PF00924 YP_002454504.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841 YP_002454505.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_002454506.1 identified by match to protein family HMM PF01656 YP_002454507.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_002454508.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002454509.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002454510.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002454511.1 identified by match to protein family HMM PF01424 YP_002454512.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation YP_002454513.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002454514.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002454884.1 identified by glimmer; putative YP_002454885.1 identified by match to protein family HMM PF01076 YP_002454886.1 identified by glimmer; putative YP_002454887.1 identified by glimmer; putative YP_002454888.1 identified by glimmer; putative YP_002454889.1 identified by match to protein family HMM PF02481 YP_002454891.1 identified by match to protein family HMM PF08378 YP_002454892.1 identified by glimmer; putative YP_002454893.1 identified by glimmer; putative YP_002454894.1 similar to pXO1-02; an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454895.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01385; match to protein family HMM TIGR01766 YP_002454900.1 identified by match to protein family HMM PF00078; match to protein family HMM PF01844 YP_002454901.1 identified by glimmer; putative YP_002454905.1 similar to pXO1-23; identified by match to protein family HMM PF00078; match to protein family HMM PF01844 YP_002454906.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002454908.1 identified by glimmer; putative YP_002454910.1 identified by glimmer; putative YP_002454912.1 identified by match to protein family HMM PF07693 YP_002454916.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002454919.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002454923.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454925.1 identified by match to protein family HMM PF05168 YP_002454926.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01909 YP_002454928.1 identified by match to protein family HMM PF00899 YP_002454929.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454937.1 identified by match to protein family HMM PF00712; match to protein family HMM PF02767; match to protein family HMM PF02768; match to protein family HMM TIGR00663 YP_002454938.1 identified by match to protein family HMM PF04098 YP_002454940.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454948.1 identified by match to protein family HMM PF01156 YP_002454949.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_002454950.1 identified by match to protein family HMM PF09397 YP_002454951.1 similar to pXO1-43 YP_002454952.1 similar to pXO1-44 YP_002454953.1 identified by match to protein family HMM PF00091 YP_002454955.1 similar to pXO1-47 YP_002454960.1 similar to pXO1-50 YP_002454961.1 similar to pXO1-51 YP_002454962.1 similar to pXO1-52 YP_002454963.1 similar to pXO1-53 YP_002454964.1 identified by match to protein family HMM PF00395 YP_002454968.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08666; match to protein family HMM TIGR03177 YP_002454970.1 identified by match to protein family HMM PF00437 YP_002454972.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454976.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002454977.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454978.1 identified by glimmer; putative YP_002454981.1 similar to pXO1-68 YP_002454984.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454986.1 identified by glimmer; putative YP_002454988.1 identified by glimmer; putative YP_002454991.1 identified by glimmer; putative YP_002454992.1 identified by glimmer; putative YP_002454993.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002454994.1 identified by glimmer; putative YP_002454997.1 identified by glimmer; putative YP_002454999.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002455001.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455003.1 identified by match to protein family HMM PF00395; match to protein family HMM PF00545; match to protein family HMM PF01473 YP_002455004.1 identified by match to protein family HMM PF01337 YP_002455008.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455009.1 identified by match to protein family HMM TIGR01784 YP_002455011.1 similar to pXO1-74 YP_002455012.1 similar to pXO1-75 YP_002455013.1 similar to pXO1-76 YP_002455014.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455015.1 identified by glimmer; putative YP_002455017.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00877; match to protein family HMM PF01551 YP_002455023.1 identified by match to protein family HMM PF03738 YP_002455025.1 identified by glimmer; putative YP_002455026.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455027.1 identified by match to protein family HMM PF02517 YP_002455028.1 identified by match to protein family HMM PF08645; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662 YP_002455029.1 identified by match to protein family HMM PF01526 YP_002455030.1 identified by match to protein family HMM PF01391 YP_002455031.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455032.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM TIGR02887 YP_002455033.1 identified by match to protein family HMM PF02796 YP_002455034.1 identified by match to protein family HMM PF01609 YP_002455035.1 identified by match to protein family HMM PF01381 YP_002455037.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002455039.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002455040.1 identified by glimmer; putative YP_002455041.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002455042.1 identified by match to protein family HMM PF01022 YP_002455043.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002455044.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383 YP_002455049.1 identified by match to protein family HMM PF00239 YP_002455050.1 identified by match to protein family HMM PF01638 YP_002455051.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_002455052.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_002455054.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine YP_002455059.1 identified by glimmer; putative YP_002455060.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002455061.1 similar to pXO1-87; identified by match to protein family HMM PF00085 YP_002455066.1 identified by match to protein family HMM PF00216 YP_002455069.1 identified by glimmer; putative YP_002455072.1 identified by glimmer; putative YP_002455076.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002455078.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01526 YP_002455079.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01526 YP_002455081.1 identified by match to protein family HMM PF03323 YP_002455082.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002455083.1 identified by match to protein family HMM TIGR02887 YP_002455084.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455085.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002455086.1 identified by match to protein family HMM PF04239; match to protein family HMM PF07870 YP_002455087.1 identified by match to protein family HMM PF07870 YP_002455088.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839 YP_002455089.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845 YP_002455090.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838 YP_002455092.1 identified by match to protein family HMM PF07870 YP_002455093.1 identified by match to protein family HMM PF02899 YP_002455095.1 identified by match to protein family HMM PF03323 YP_002455096.1 identified by match to protein family HMM PF01520 YP_002455098.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455100.1 identified by match to protein family HMM PF00583 YP_002455101.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455102.1 identified by match to protein family HMM PF00665; match to protein family HMM PF09299 YP_002455104.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002455105.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002455106.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002455107.1 identified by match to protein family HMM PF03323 YP_002455108.1 identified by match to protein family HMM TIGR02887 YP_002455110.1 identified by glimmer; putative YP_002455111.1 identified by glimmer; putative YP_002455112.1 identified by match to protein family HMM PF00496 YP_002455113.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455115.1 identified by glimmer; putative YP_002455116.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002455117.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002455118.1 similar to pXO1-101 YP_002455122.1 identified by match to protein family HMM PF06013 YP_002455123.1 identified by match to protein family HMM PF09346 YP_002455126.1 identified by match to protein family HMM PF01022 YP_002455131.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867 YP_002455135.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002455136.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002455137.1 identified by match to protein family HMM PF00394; match to protein family HMM PF07731; match to protein family HMM PF07732 YP_002455138.1 identified by match to protein family HMM PF00264 YP_002455139.1 identified by match to protein family HMM PF00005 YP_002455140.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002455141.1 identified by match to protein family HMM PF00497 YP_002455142.1 identified by match to protein family HMM PF01077 YP_002455143.1 identified by match to protein family HMM PF00085 YP_002455144.1 identified by glimmer; putative YP_002455145.1 identified by match to protein family HMM PF01551; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002455147.1 identified by match to protein family HMM PF07040 YP_002455150.1 identified by match to protein family HMM PF02683 YP_002455151.1 identified by match to protein family HMM PF02012 YP_002455153.1 identified by glimmer; putative YP_002455154.1 identified by match to protein family HMM PF03860 YP_002455155.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002455156.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF02630; match to protein family HMM PF08534 YP_002455160.1 identified by match to protein family HMM PF01297 YP_002455161.1 identified by match to protein family HMM PF02583 YP_002455162.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002455163.1 identified by match to protein family HMM PF00403; match to protein family HMM TIGR00003 YP_002455165.1 identified by match to protein family HMM PF08721; match to protein family HMM PF08722 YP_002455168.1 identified by match to protein family HMM TIGR03609 YP_002455169.1 identified by glimmer; putative YP_002455171.1 identified by match to protein family HMM PF03773 YP_002455172.1 identified by match to protein family HMM PF01047 YP_002455173.1 identified by match to protein family HMM PF02627 YP_002455174.1 identified by match to protein family HMM PF01071; match to protein family HMM PF02655; match to protein family HMM PF08443 YP_002455175.1 identified by match to protein family HMM PF01022 YP_002455176.1 identified by match to protein family HMM PF01384 YP_002455177.1 identified by match to protein family HMM PF00515; match to protein family HMM PF01381 YP_002455178.1 identified by match to protein family HMM PF04055 YP_002455179.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002455180.1 identified by match to protein family HMM PF02492 YP_002455182.1 identified by match to protein family HMM PF00583 YP_002455184.1 identified by match to protein family HMM PF01022 YP_002455185.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832 YP_002455186.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_002455187.1 identified by match to protein family HMM PF06953 YP_002455188.1 identified by match to protein family HMM PF02374; match to protein family HMM TIGR00345 YP_002455189.1 identified by match to protein family HMM PF01521 YP_002455191.1 identified by glimmer; putative YP_002455193.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_002455196.1 similar to pXO1-134 YP_002455197.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455199.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455200.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002455201.1 identified by match to protein family HMM PF01022 YP_002455202.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02600 YP_002455205.1 identified by match to protein family HMM PF00565 YP_002455207.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01396; match to protein family HMM PF01751