-- dump date 20140618_221030 -- class Genbank::CDS -- table cds_note -- id note YP_002443553.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002443554.1 binds the polymerase to DNA and acts as a sliding clamp YP_002443555.1 identified by match to protein family HMM TIGR02988 YP_002443556.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002443557.1 negatively supercoils closed circular double-stranded DNA YP_002443558.1 negatively supercoils closed circular double-stranded DNA YP_002443560.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002443561.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002443562.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_002443563.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_002443564.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002443565.1 identified by glimmer YP_002443566.1 identified by match to protein family HMM PF01712 YP_002443567.1 identified by match to protein family HMM PF01712 YP_002443568.1 identified by match to protein family HMM PF00857 YP_002443569.1 identified by match to protein family HMM PF00383 YP_002443570.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002443571.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002443572.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002443574.1 identified by match to protein family HMM PF07441; match to protein family HMM TIGR02862 YP_002443576.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002443577.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002443578.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002443579.1 identified by match to protein family HMM PF04468 YP_002443580.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_002443582.1 identified by match to protein family HMM PF01541 YP_002443583.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002443584.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002443585.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002443586.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002443587.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334 YP_002443588.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002443589.1 identified by match to protein family HMM PF05582; match to protein family HMM TIGR02855 YP_002443590.1 identified by match to protein family HMM PF06257 YP_002443592.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002443593.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743 YP_002443594.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002443595.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus YP_002443596.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002443597.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002443598.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002443600.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002443601.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851 YP_002443602.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002443603.1 identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444 YP_002443604.1 identified by match to protein family HMM PF01479 YP_002443605.1 identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892 YP_002443606.1 identified by match to protein family HMM PF09578; match to protein family HMM TIGR02893 YP_002443607.1 identified by match to protein family HMM PF04977 YP_002443608.1 identified by match to protein family HMM PF00575 YP_002443609.1 identified by match to protein family HMM PF07228; match to protein family HMM TIGR02865 YP_002443610.1 identified by match to protein family HMM PF01171; match to protein family HMM PF06508; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433 YP_002443611.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002443612.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM PF07728; match to protein family HMM TIGR01241 YP_002443613.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_002443614.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002443615.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002443616.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715 YP_002443617.1 amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis YP_002443618.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002443619.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002443620.1 identified by match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526 YP_002443621.1 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498 YP_002443622.1 identified by match to protein family HMM PF01381 YP_002443623.1 identified by match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002443624.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002443625.1 identified by match to protein family HMM PF05848 YP_002443626.1 identified by match to protein family HMM PF02151 YP_002443627.1 identified by match to protein family HMM PF00217 YP_002443628.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002443629.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002443630.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair YP_002443631.1 identified by match to protein family HMM PF01850; match to protein family HMM PF01938 YP_002443632.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002443633.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002443634.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002443635.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172 YP_002443636.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002443637.1 identified by match to protein family HMM PF00636 YP_002443638.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186 YP_002443639.1 identified by match to protein family HMM PF05991 YP_002443640.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002443641.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002443642.1 Modulates Rho-dependent transcription termination YP_002443643.1 binds directly to 23S ribosomal RNA YP_002443644.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002443645.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002443646.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002443647.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_002443648.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002443649.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002443650.1 identified by match to protein family HMM PF01248 YP_002443651.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002443652.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002443653.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002443654.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002443655.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002443656.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002443657.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002443658.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002443659.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002443660.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00203; match to protein family HMM TIGR01050 YP_002443661.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002443662.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002443663.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002443664.1 one of the stabilizing components for the large ribosomal subunit YP_002443665.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002443666.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002443667.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002443668.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002443669.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_002443670.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002443671.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002443672.1 binds 5S rRNA along with protein L5 and L25 YP_002443673.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002443674.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002443675.1 late assembly protein YP_002443676.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002443677.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002443678.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002443679.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002443680.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002443681.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002443682.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002443683.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002443684.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002443685.1 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_002443686.1 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_002443687.1 identified by match to protein family HMM PF02361 YP_002443688.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002443689.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002443690.1 forms a direct contact with the tRNA during translation YP_002443692.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR02883 YP_002443696.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02764 YP_002443698.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002443699.1 identified by match to protein family HMM PF00491; match to protein family HMM TIGR01229 YP_002443700.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159 YP_002443701.1 identified by match to protein family HMM PF07949 YP_002443702.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002443703.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002443704.1 identified by match to protein family HMM PF00326 YP_002443706.1 identified by match to protein family HMM PF04173; match to protein family HMM PF07681 YP_002443707.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002443708.1 identified by match to protein family HMM PF00528 YP_002443709.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002443710.1 identified by match to protein family HMM PF03180 YP_002443711.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002443713.1 identified by match to protein family HMM PF01565 YP_002443716.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_002443717.1 identified by glimmer YP_002443719.1 identified by glimmer YP_002443720.1 identified by match to protein family HMM PF00528 YP_002443721.1 identified by match to protein family HMM PF00528 YP_002443722.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002443723.1 identified by match to protein family HMM PF00005 YP_002443724.1 identified by match to protein family HMM PF00496 YP_002443727.1 identified by match to protein family HMM PF00496 YP_002443728.1 identified by match to protein family HMM PF00496 YP_002443729.1 identified by match to protein family HMM PF00248 YP_002443730.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002443732.1 identified by match to protein family HMM PF06800 YP_002443733.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02141 YP_002443734.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256 YP_002443735.1 identified by match to protein family HMM TIGR01764 YP_002443736.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002443737.1 identified by match to protein family HMM PF00892 YP_002443738.1 identified by glimmer YP_002443739.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002443740.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002443741.1 identified by glimmer YP_002443742.1 identified by match to protein family HMM PF02588 YP_002443743.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002443744.1 identified by glimmer YP_002443745.1 identified by match to protein family HMM PF01026 YP_002443747.1 identified by match to protein family HMM PF01464 YP_002443748.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002443749.1 identified by glimmer YP_002443751.1 identified by match to protein family HMM PF00005 YP_002443752.1 identified by glimmer YP_002443753.1 identified by match to protein family HMM PF00496 YP_002443754.1 identified by match to protein family HMM PF00528 YP_002443755.1 identified by match to protein family HMM PF00528 YP_002443756.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002443757.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002443758.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002443759.1 identified by glimmer YP_002443760.1 identified by glimmer YP_002443761.1 identified by glimmer YP_002443762.1 identified by glimmer YP_002443763.1 identified by match to protein family HMM PF00903; match to protein family HMM TIGR01263 YP_002443764.1 identified by match to protein family HMM PF01557 YP_002443765.1 identified by match to protein family HMM PF04209 YP_002443766.1 identified by match to protein family HMM PF00324 YP_002443767.1 identified by match to protein family HMM PF07690 YP_002443768.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002443769.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002443770.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002443771.1 identified by match to protein family HMM PF03851; match to protein family HMM TIGR00629 YP_002443772.1 identified by match to protein family HMM PF01694 YP_002443773.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002443775.1 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492 YP_002443777.1 identified by match to protein family HMM PF02452 YP_002443778.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371 YP_002443779.1 identified by match to protein family HMM PF03926 YP_002443780.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150 YP_002443781.1 identified by match to protein family HMM PF00814 YP_002443782.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002443783.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002443784.1 identified by match to protein family HMM PF00005 YP_002443785.1 modulates transcription in response to the NADH/NAD(+) redox state YP_002443787.1 identified by match to protein family HMM PF02517 YP_002443788.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002443789.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002443790.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002443791.1 identified by match to protein family HMM PF00860 YP_002443792.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002443793.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002443795.1 identified by match to protein family HMM PF01323 YP_002443797.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01619 YP_002443798.1 identified by match to protein family HMM PF04266 YP_002443799.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002443801.1 identified by match to protein family HMM PF00005 YP_002443802.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002443803.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002443804.1 identified by match to protein family HMM PF00892 YP_002443806.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002443807.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002443808.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002443809.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002443810.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_002443811.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002443812.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002443813.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002443814.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002443815.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002443816.1 involved in de novo purine biosynthesis YP_002443817.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002443819.1 identified by match to protein family HMM PF01145 YP_002443822.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer YP_002443823.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073 YP_002443824.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002443825.1 identified by match to protein family HMM PF07537 YP_002443826.1 identified by match to protein family HMM PF01925 YP_002443827.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_002443828.1 identified by match to protein family HMM PF00857 YP_002443829.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002443830.1 identified by match to protein family HMM PF00528 YP_002443831.1 identified by match to protein family HMM PF03180 YP_002443833.1 identified by glimmer YP_002443834.1 identified by match to protein family HMM PF02374; match to protein family HMM TIGR00345 YP_002443835.1 identified by match to protein family HMM PF01047 YP_002443836.1 identified by match to protein family HMM PF05360 YP_002443837.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_002443838.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002443839.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002443840.1 similar to YegS from E. coli YP_002443841.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002443842.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002443843.1 identified by match to protein family HMM PF00158; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002443844.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01780 YP_002443845.1 identified by match to protein family HMM PF00893 YP_002443847.1 identified by match to protein family HMM PF02073 YP_002443848.1 identified by match to protein family HMM PF01522 YP_002443849.1 identified by glimmer YP_002443851.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002443852.1 identified by match to protein family HMM PF01938; match to protein family HMM PF02475; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002443853.1 identified by match to protein family HMM PF01207 YP_002443854.1 identified by match to protein family HMM PF07308 YP_002443855.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01863 YP_002443856.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002443858.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002443860.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002443861.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002443863.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_002443864.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR03137 YP_002443865.1 related protein from Bacillus subtilis functions as methylribose kinase and functions in salvage pathway YP_002443866.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_002443867.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002443868.1 identified by match to protein family HMM PF01032 YP_002443869.1 identified by match to protein family HMM PF01032 YP_002443870.1 identified by match to protein family HMM PF01497 YP_002443871.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002443872.1 identified by glimmer YP_002443873.1 identified by match to protein family HMM TIGR01764 YP_002443877.1 identified by glimmer YP_002443878.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002443879.1 identified by glimmer YP_002443880.1 identified by match to protein family HMM PF04199 YP_002443883.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002443884.1 identified by match to protein family HMM PF00355; match to protein family HMM PF01266 YP_002443885.1 identified by match to protein family HMM PF00487 YP_002443886.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002443887.1 identified by match to protein family HMM PF00497 YP_002443888.1 identified by match to protein family HMM PF00005 YP_002443889.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002443890.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529 YP_002443891.1 catalyzes the degradation of arginine to citruline and ammonia YP_002443892.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002443893.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002443894.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002443895.1 identified by match to protein family HMM PF00027 YP_002443897.1 identified by match to protein family HMM PF01565; match to protein family HMM PF08031 YP_002443898.1 identified by match to protein family HMM PF00128 YP_002443899.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02003 YP_002443900.1 identified by match to protein family HMM PF03372 YP_002443901.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002443902.1 decatenates replicating daughter chromosomes YP_002443903.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002443904.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_002443905.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002443906.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002443907.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF07993; match to protein family HMM TIGR01733; match to protein family HMM TIGR01746 YP_002443908.1 identified by match to protein family HMM PF01910 YP_002443909.1 identified by match to protein family HMM PF00528 YP_002443910.1 identified by match to protein family HMM PF09084 YP_002443911.1 identified by match to protein family HMM PF00005 YP_002443912.1 identified by match to protein family HMM PF00005 YP_002443913.1 identified by match to protein family HMM PF00041; match to protein family HMM PF00553; match to protein family HMM PF00704 YP_002443914.1 identified by match to protein family HMM PF09350 YP_002443916.1 identified by glimmer YP_002443918.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08360 YP_002443919.1 identified by match to protein family HMM PF07690 YP_002443920.1 identified by match to protein family HMM PF01381 YP_002443921.1 identified by match to protein family HMM PF07690 YP_002443922.1 identified by match to protein family HMM PF01663 YP_002443924.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002443925.1 identified by match to protein family HMM TIGR01167 YP_002443926.1 identified by match to protein family HMM PF00480 YP_002443927.1 identified by match to protein family HMM PF02342 YP_002443928.1 identified by match to protein family HMM PF02342 YP_002443929.1 identified by match to protein family HMM PF02342 YP_002443930.1 identified by match to protein family HMM PF03741 YP_002443932.1 identified by match to protein family HMM PF05816 YP_002443933.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002443934.1 identified by match to protein family HMM PF06569 YP_002443935.1 identified by match to protein family HMM PF01451 YP_002443937.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765 YP_002443938.1 identified by glimmer YP_002443939.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525 YP_002443940.1 identified by match to protein family HMM PF00892 YP_002443941.1 identified by match to protein family HMM PF07947 YP_002443942.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002443943.1 identified by glimmer YP_002443944.1 identified by match to protein family HMM PF09335 YP_002443945.1 identified by match to protein family HMM PF00892 YP_002443947.1 identified by match to protein family HMM PF01243 YP_002443948.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00378; match to protein family HMM TIGR00846 YP_002443950.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08756 YP_002443952.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002443953.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02884 YP_002443954.1 identified by match to protein family HMM PF00730 YP_002443955.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002443957.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002443958.1 identified by glimmer YP_002443959.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR00229 YP_002443961.1 identified by match to protein family HMM PF00324 YP_002443962.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_002443963.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06803 YP_002443964.1 identified by match to protein family HMM TIGR02840 YP_002443965.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002443967.1 catalyzes the formation of glutamate from glutamine YP_002443968.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01998 YP_002443969.1 identified by match to protein family HMM PF00144 YP_002443970.1 identified by glimmer YP_002443972.1 identified by match to protein family HMM PF00535 YP_002443973.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002443974.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002443975.1 identified by match to protein family HMM PF00535 YP_002443976.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002443977.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493 YP_002443978.1 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids YP_002443981.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002443982.1 identified by match to protein family HMM PF01370; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_002443983.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002443984.1 identified by match to protein family HMM PF08838 YP_002443985.1 SASP K; found in the forespore compartment YP_002443987.1 identified by match to protein family HMM PF04307 YP_002443988.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002443990.1 identified by match to protein family HMM PF04259; match to protein family HMM TIGR01442 YP_002443993.1 identified by match to protein family HMM PF04167 YP_002443994.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002443995.1 identified by match to protein family HMM PF06081 YP_002443996.1 identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898 YP_002443997.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_002443998.1 identified by match to protein family HMM PF00005 YP_002443999.1 identified by match to protein family HMM PF06182 YP_002444000.1 identified by match to protein family HMM PF06182 YP_002444001.1 identified by match to protein family HMM PF07885 YP_002444002.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002444003.1 identified by match to protein family HMM PF01475 YP_002444004.1 identified by match to protein family HMM PF00583 YP_002444007.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002444008.1 identified by match to protein family HMM PF00293 YP_002444009.1 identified by match to protein family HMM PF00912 YP_002444010.1 identified by match to protein family HMM PF01323 YP_002444011.1 identified by match to protein family HMM PF00037; match to protein family HMM PF03130; match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_002444013.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00185 YP_002444014.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002444015.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_002444016.1 identified by match to protein family HMM PF04285; match to protein family HMM TIGR02877 YP_002444017.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05031; match to protein family HMM TIGR01167 YP_002444018.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842 YP_002444019.1 identified by match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453 YP_002444020.1 identified by match to protein family HMM PF01957 YP_002444021.1 identified by match to protein family HMM PF01145 YP_002444022.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002444023.1 identified by match to protein family HMM PF00989; match to protein family HMM PF02518 YP_002444024.1 identified by match to protein family HMM PF00072 YP_002444025.1 identified by match to protein family HMM PF03600; match to protein family HMM PF03606; match to protein family HMM PF06808; match to protein family HMM TIGR00784 YP_002444028.1 identified by match to protein family HMM PF00023 YP_002444030.1 identified by match to protein family HMM PF04309 YP_002444031.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_002444032.1 identified by match to protein family HMM PF00528 YP_002444033.1 identified by match to protein family HMM PF00528 YP_002444034.1 identified by match to protein family HMM PF01547 YP_002444035.1 identified by match to protein family HMM PF00149 YP_002444036.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444037.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002444038.1 identified by glimmer YP_002444039.1 identified by glimmer YP_002444041.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002444042.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002444043.1 identified by match to protein family HMM PF00072 YP_002444044.1 identified by match to protein family HMM PF03390 YP_002444045.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949 YP_002444047.1 identified by match to protein family HMM PF00892 YP_002444048.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002444049.1 identified by match to protein family HMM PF00583 YP_002444050.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002444051.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444052.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002444055.1 identified by match to protein family HMM PF00583 YP_002444056.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002444057.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_002444058.1 identified by match to protein family HMM PF07849 YP_002444059.1 identified by match to protein family HMM PF03009 YP_002444060.1 identified by match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF05222; match to protein family HMM TIGR00518 YP_002444061.1 identified by match to protein family HMM PF00324 YP_002444062.1 identified by match to protein family HMM PF01022 YP_002444063.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525 YP_002444064.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002444065.1 identified by match to protein family HMM PF00515; match to protein family HMM PF01381; match to protein family HMM PF07719 YP_002444067.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002444068.1 identified by match to protein family HMM PF09335 YP_002444070.1 identified by glimmer YP_002444071.1 identified by match to protein family HMM PF04294 YP_002444072.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002444073.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002444074.1 identified by match to protein family HMM PF00903 YP_002444075.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002444076.1 catalyzes the formation of fumarate from aspartate YP_002444077.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002444078.1 identified by glimmer YP_002444079.1 identified by match to protein family HMM PF01022 YP_002444080.1 SASP H; spore coat; expressed in forespore compartment YP_002444081.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002444082.1 identified by match to protein family HMM PF01497 YP_002444083.1 identified by match to protein family HMM PF01032 YP_002444084.1 identified by match to protein family HMM PF01032 YP_002444085.1 identified by match to protein family HMM PF00005 YP_002444086.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002444087.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002444088.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993 YP_002444089.1 identified by match to protein family HMM PF00293 YP_002444091.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002444092.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002444094.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002444095.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03222 YP_002444096.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404 YP_002444097.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992 YP_002444098.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002444099.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002444100.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002444101.1 identified by match to protein family HMM PF03323 YP_002444102.1 identified by match to protein family HMM PF01636 YP_002444103.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002444104.1 identified by match to protein family HMM PF00005 YP_002444105.1 identified by match to protein family HMM PF00497 YP_002444106.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002444107.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002444108.1 identified by match to protein family HMM PF00324 YP_002444109.1 identified by match to protein family HMM PF02566 YP_002444110.1 identified by match to protein family HMM PF01230 YP_002444111.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002444113.1 identified by match to protein family HMM PF08279 YP_002444114.1 identified by match to protein family HMM PF01872 YP_002444115.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002444116.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444118.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002444119.1 identified by match to protein family HMM PF00582 YP_002444120.1 identified by glimmer YP_002444121.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00712; match to protein family HMM TIGR00881 YP_002444122.1 identified by glimmer YP_002444123.1 identified by match to protein family HMM PF01047 YP_002444124.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002444125.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002444126.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152 YP_002444127.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002444128.1 identified by match to protein family HMM PF00005 YP_002444129.1 identified by match to protein family HMM PF02653 YP_002444130.1 identified by match to protein family HMM PF00532 YP_002444131.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_002444132.1 identified by match to protein family HMM PF05547; match to protein family HMM TIGR03296 YP_002444135.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002444136.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002444137.1 identified by match to protein family HMM PF07885 YP_002444138.1 identified by match to protein family HMM PF00882 YP_002444139.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR03395 YP_002444141.1 identified by match to protein family HMM PF01565; match to protein family HMM PF04030; match to protein family HMM TIGR01679 YP_002444142.1 identified by match to protein family HMM PF04892 YP_002444143.1 identified by glimmer YP_002444145.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002444146.1 identified by match to protein family HMM PF00015 YP_002444147.1 identified by match to protein family HMM PF06725 YP_002444148.1 identified by match to protein family HMM PF01381 YP_002444150.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002444152.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002444154.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002444157.1 identified by match to protein family HMM PF00324 YP_002444158.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002444159.1 identified by match to protein family HMM PF01381 YP_002444160.1 identified by glimmer YP_002444161.1 identified by match to protein family HMM PF00583 YP_002444162.1 identified by glimmer YP_002444163.1 identified by match to protein family HMM PF00999; match to protein family HMM PF02080; match to protein family HMM PF02254 YP_002444164.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02901 YP_002444165.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02897 YP_002444166.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02882 YP_002444167.1 identified by match to protein family HMM PF02790; match to protein family HMM TIGR01432 YP_002444168.1 identified by match to protein family HMM PF00324 YP_002444170.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002444172.1 identified by match to protein family HMM PF00474 YP_002444173.1 identified by match to protein family HMM PF03323 YP_002444174.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002444175.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002444176.1 identified by glimmer YP_002444177.1 identified by match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670 YP_002444178.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231 YP_002444179.1 identified by match to protein family HMM PF04023 YP_002444180.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136 YP_002444181.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002444182.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002444184.1 identified by match to protein family HMM PF00873 YP_002444185.1 identified by match to protein family HMM PF00571 YP_002444187.1 identified by glimmer YP_002444188.1 identified by match to protein family HMM PF00078; match to protein family HMM PF01348 YP_002444191.1 identified by match to protein family HMM PF01551; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002444192.1 identified by match to protein family HMM PF03070 YP_002444193.1 identified by match to protein family HMM PF00005 YP_002444194.1 identified by match to protein family HMM PF00528 YP_002444195.1 identified by match to protein family HMM PF09084 YP_002444196.1 regulates the production of extracellular enzymes YP_002444197.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR02352 YP_002444198.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_002444199.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002444200.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002444201.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002444202.1 identified by glimmer YP_002444203.1 identified by glimmer YP_002444204.1 identified by glimmer YP_002444205.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002444206.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002444207.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_002444208.1 identified by match to protein family HMM PF00582; match to protein family HMM PF02702 YP_002444209.1 identified by match to protein family HMM PF07690 YP_002444210.1 identified by match to protein family HMM PF01047 YP_002444211.1 identified by match to protein family HMM PF01734 YP_002444212.1 identified by glimmer YP_002444213.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002444214.1 identified by match to protein family HMM PF00106 YP_002444215.1 identified by match to protein family HMM PF03734 YP_002444217.1 identified by match to protein family HMM PF07561 YP_002444218.1 identified by match to protein family HMM PF00085 YP_002444219.1 identified by match to protein family HMM PF02600 YP_002444222.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002444223.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002444224.1 identified by match to protein family HMM PF03323 YP_002444226.1 identified by match to protein family HMM PF00881 YP_002444227.1 identified by match to protein family HMM PF04293 YP_002444229.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444230.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444232.1 identified by match to protein family HMM PF02583 YP_002444233.1 identified by match to protein family HMM PF00581; match to protein family HMM PF01206 YP_002444234.1 identified by match to protein family HMM PF00753 YP_002444235.1 identified by match to protein family HMM PF01206 YP_002444236.1 identified by match to protein family HMM PF00581 YP_002444237.1 identified by match to protein family HMM PF00581 YP_002444238.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444239.1 identified by match to protein family HMM PF01925 YP_002444240.1 identified by glimmer YP_002444241.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002444242.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_002444243.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704 YP_002444244.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF07690 YP_002444245.1 identified by match to protein family HMM PF05913 YP_002444246.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002444247.1 identified by match to protein family HMM PF02255 YP_002444248.1 identified by match to protein family HMM PF02302 YP_002444249.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002444250.1 identified by glimmer YP_002444251.1 identified by match to protein family HMM PF05913 YP_002444252.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002444253.1 identified by match to protein family HMM PF02687 YP_002444254.1 identified by match to protein family HMM PF00005 YP_002444255.1 identified by match to protein family HMM TIGR01730 YP_002444256.1 identified by match to protein family HMM PF09529; match to protein family HMM TIGR02206 YP_002444257.1 identified by match to protein family HMM PF00528 YP_002444258.1 identified by match to protein family HMM PF00528 YP_002444259.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002444260.1 identified by match to protein family HMM PF05067 YP_002444265.1 identified by match to protein family HMM PF02735; match to protein family HMM TIGR02772 YP_002444266.1 identified by match to protein family HMM PF06803 YP_002444267.1 identified by match to protein family HMM PF09335 YP_002444268.1 identified by glimmer YP_002444269.1 identified by glimmer YP_002444271.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444272.1 identified by match to protein family HMM PF00041; match to protein family HMM PF00149 YP_002444274.1 identified by glimmer YP_002444275.1 identified by match to protein family HMM PF00324 YP_002444276.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00932 YP_002444278.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002444279.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002444280.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378 YP_002444281.1 identified by match to protein family HMM PF05913 YP_002444282.1 identified by match to protein family HMM PF07681 YP_002444285.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_002444286.1 identified by match to protein family HMM PF01037 YP_002444287.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_002444288.1 identified by match to protein family HMM PF00106 YP_002444289.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278 YP_002444291.1 identified by match to protein family HMM PF00893 YP_002444292.1 identified by match to protein family HMM PF00893 YP_002444293.1 identified by match to protein family HMM PF00440 YP_002444294.1 identified by match to protein family HMM PF00083; match to protein family HMM PF05978; match to protein family HMM PF07690 YP_002444295.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01638 YP_002444296.1 identified by match to protein family HMM PF07366 YP_002444297.1 identified by match to protein family HMM PF02525 YP_002444299.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_002444300.1 identified by match to protein family HMM PF00199; match to protein family HMM PF06628 YP_002444301.1 identified by match to protein family HMM PF05975 YP_002444302.1 identified by match to protein family HMM PF00324 YP_002444303.1 identified by match to protein family HMM PF00171 YP_002444304.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444305.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002444306.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002444307.1 identified by match to protein family HMM PF00497 YP_002444308.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002444309.1 identified by match to protein family HMM PF00005 YP_002444310.1 identified by match to protein family HMM PF00269 YP_002444314.1 identified by match to protein family HMM PF04286 YP_002444315.1 identified by match to protein family HMM PF06133 YP_002444317.1 identified by match to protein family HMM PF02518 YP_002444318.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002444320.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM TIGR01167 YP_002444323.1 identified by match to protein family HMM PF06030 YP_002444326.1 identified by match to protein family HMM PF08006 YP_002444327.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_002444328.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252 YP_002444329.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_002444330.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01484 YP_002444331.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002444332.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01510 YP_002444333.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002444334.1 activates fatty acids by binding to coenzyme A YP_002444336.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM PF00955; match to protein family HMM PF01740 YP_002444337.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002444338.1 identified by match to protein family HMM PF04230; match to protein family HMM TIGR03609 YP_002444339.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01832 YP_002444341.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002444344.1 identified by glimmer YP_002444345.1 identified by match to protein family HMM PF05343 YP_002444346.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01520 YP_002444347.1 identified by match to protein family HMM PF01170 YP_002444349.1 identified by match to protein family HMM PF05544 YP_002444350.1 catalyzes the formation of L-proline from L-ornithine YP_002444351.1 identified by match to protein family HMM PF00496 YP_002444352.1 identified by match to protein family HMM PF00528 YP_002444353.1 identified by match to protein family HMM PF00528 YP_002444354.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002444355.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002444357.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00753 YP_002444359.1 identified by match to protein family HMM PF07366 YP_002444361.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF01073; match to protein family HMM PF07993; match to protein family HMM TIGR01733 YP_002444362.1 identified by glimmer YP_002444363.1 identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928 YP_002444366.1 identified by match to protein family HMM PF00899 YP_002444367.1 identified by match to protein family HMM PF07690 YP_002444368.1 identified by match to protein family HMM PF05163 YP_002444369.1 identified by glimmer YP_002444370.1 identified by glimmer YP_002444371.1 identified by glimmer YP_002444373.1 identified by match to protein family HMM PF01527 YP_002444374.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002444375.1 identified by match to protein family HMM PF06013 YP_002444379.1 identified by match to protein family HMM PF09346 YP_002444380.1 identified by match to protein family HMM PF09346 YP_002444381.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444383.1 identified by glimmer YP_002444385.1 identified by glimmer YP_002444386.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444388.1 identified by glimmer YP_002444390.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002444391.1 identified by match to protein family HMM PF02518 YP_002444392.1 identified by match to protein family HMM PF00072 YP_002444393.1 identified by match to protein family HMM PF03401 YP_002444394.1 identified by glimmer YP_002444395.1 identified by match to protein family HMM PF04471 YP_002444396.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444397.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444398.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002444399.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002444400.1 identified by glimmer YP_002444401.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002444403.1 identified by glimmer YP_002444405.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002444406.1 unwinds double stranded DNA YP_002444408.1 identified by match to protein family HMM PF01978 YP_002444409.1 identified by match to protein family HMM PF01925 YP_002444411.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002444412.1 identified by glimmer YP_002444414.1 identified by glimmer YP_002444415.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002444416.1 identified by match to protein family HMM PF00583 YP_002444418.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002444419.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002444422.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002444425.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002444426.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444428.1 identified by match to protein family HMM PF07336 YP_002444429.1 identified by match to protein family HMM PF04982 YP_002444430.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002444432.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444433.1 identified by match to protein family HMM PF01047 YP_002444434.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473 YP_002444436.1 identified by glimmer YP_002444437.1 identified by match to protein family HMM PF07690 YP_002444439.1 identified by match to protein family HMM PF04892 YP_002444440.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone YP_002444441.1 identified by match to protein family HMM TIGR02366 YP_002444442.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_002444443.1 identified by glimmer YP_002444448.1 identified by match to protein family HMM PF01381 YP_002444449.1 identified by glimmer YP_002444451.1 identified by match to protein family HMM PF00395 YP_002444452.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444453.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03551 YP_002444455.1 identified by glimmer YP_002444457.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance YP_002444461.1 identified by match to protein family HMM PF05532 YP_002444462.1 identified by match to protein family HMM PF04226 YP_002444463.1 identified by glimmer YP_002444464.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377 YP_002444465.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_002444466.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase YP_002444467.1 identified by match to protein family HMM PF00210 YP_002444468.1 identified by match to protein family HMM PF00072; match to protein family HMM PF07228 YP_002444469.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705 YP_002444470.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01590; match to protein family HMM PF02518 YP_002444472.1 identified by glimmer YP_002444474.1 identified by glimmer YP_002444475.1 identified by match to protein family HMM PF01906 YP_002444476.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444478.1 identified by match to protein family HMM PF07690 YP_002444479.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002444480.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002444481.1 identified by match to protein family HMM PF02275 YP_002444483.1 identified by glimmer YP_002444485.1 identified by match to protein family HMM PF00149 YP_002444487.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_002444488.1 identified by match to protein family HMM PF08921 YP_002444489.1 identified by match to protein family HMM PF01810 YP_002444490.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444491.1 identified by match to protein family HMM PF00903 YP_002444492.1 identified by match to protein family HMM PF00903 YP_002444495.1 identified by match to protein family HMM PF00561 YP_002444498.1 identified by glimmer YP_002444499.1 identified by match to protein family HMM PF00190; match to protein family HMM PF07883; match to protein family HMM TIGR03404 YP_002444500.1 identified by glimmer YP_002444501.1 identified by match to protein family HMM PF04309 YP_002444502.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002444503.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002444504.1 identified by match to protein family HMM PF01266 YP_002444505.1 identified by glimmer YP_002444506.1 part of sigC operon induced by temperature upshift YP_002444507.1 part of sigC operon that is induced by temperature upshift YP_002444509.1 identified by match to protein family HMM PF00580 YP_002444510.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002444511.1 identified by glimmer YP_002444512.1 identified by match to protein family HMM PF08963 YP_002444513.1 hpr; ScoC; MarR family; protease production regulatory protein YP_002444515.1 identified by match to protein family HMM PF01230 YP_002444516.1 identified by match to protein family HMM PF00005 YP_002444517.1 identified by match to protein family HMM PF05975 YP_002444519.1 identified by match to protein family HMM PF00440 YP_002444520.1 identified by glimmer YP_002444521.1 identified by match to protein family HMM PF03703 YP_002444522.1 identified by match to protein family HMM PF03703 YP_002444523.1 identified by match to protein family HMM PF06161 YP_002444525.1 identified by match to protein family HMM PF00440 YP_002444526.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05737; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002444528.1 identified by match to protein family HMM PF00106 YP_002444529.1 identified by match to protein family HMM PF00892 YP_002444530.1 identified by match to protein family HMM PF03703 YP_002444531.1 identified by match to protein family HMM PF03703 YP_002444532.1 identified by match to protein family HMM PF03992 YP_002444533.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002444534.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002444535.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002444536.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_002444537.1 identified by glimmer YP_002444538.1 identified by match to protein family HMM PF03372 YP_002444541.1 identified by glimmer YP_002444542.1 identified by match to protein family HMM PF00440 YP_002444543.1 identified by match to protein family HMM PF01061; match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002444546.1 identified by glimmer YP_002444547.1 identified by match to protein family HMM PF00583 YP_002444548.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002444550.1 identified by match to protein family HMM PF00753 YP_002444551.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545 YP_002444553.1 activates fatty acids by binding to coenzyme A YP_002444555.1 identified by glimmer YP_002444556.1 identified by glimmer YP_002444558.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444559.1 identified by match to protein family HMM PF00440 YP_002444561.1 identified by match to protein family HMM PF00149 YP_002444562.1 identified by match to protein family HMM PF01966 YP_002444564.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002444565.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002444566.1 identified by match to protein family HMM PF00903 YP_002444567.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002444568.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444569.1 identified by match to protein family HMM PF02517 YP_002444570.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444571.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444572.1 identified by glimmer YP_002444573.1 identified by match to protein family HMM PF01435 YP_002444574.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002444575.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444576.1 identified by match to protein family HMM PF00395 YP_002444577.1 identified by match to protein family HMM PF00395 YP_002444578.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002444579.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_002444580.1 identified by match to protein family HMM PF01636 YP_002444582.1 identified by match to protein family HMM PF00313 YP_002444584.1 identified by match to protein family HMM PF06338 YP_002444585.1 identified by match to protein family HMM PF09335 YP_002444586.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002444587.1 identified by match to protein family HMM TIGR02773 YP_002444588.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785 YP_002444589.1 identified by match to protein family HMM PF03118 YP_002444596.1 identified by match to protein family HMM PF09388 YP_002444597.1 identified by match to protein family HMM PF01557 YP_002444598.1 identified by glimmer YP_002444599.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR01885 YP_002444600.1 identified by match to protein family HMM PF07457 YP_002444602.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 YP_002444603.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002444604.1 identified by match to protein family HMM PF00199 YP_002444605.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_002444606.1 identified by match to protein family HMM PF00128 YP_002444607.1 identified by match to protein family HMM PF01381 YP_002444608.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002444610.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002444612.1 identified by match to protein family HMM PF02588 YP_002444615.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002444616.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444617.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_002444622.1 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002444623.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002444626.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002444627.1 identified by glimmer YP_002444628.1 identified by match to protein family HMM PF00496 YP_002444629.1 identified by match to protein family HMM PF00528 YP_002444630.1 identified by match to protein family HMM PF00528 YP_002444631.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002444632.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002444633.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002444634.1 identified by match to protein family HMM PF00496 YP_002444635.1 identified by glimmer YP_002444636.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002444637.1 identified by match to protein family HMM PF03741 YP_002444638.1 identified by glimmer YP_002444639.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002444640.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002444641.1 identified by match to protein family HMM PF06054 YP_002444642.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002444645.1 identified by match to protein family HMM PF01152 YP_002444646.1 identified by match to protein family HMM PF01928 YP_002444648.1 identified by match to protein family HMM PF04607 YP_002444649.1 catalyzes the phosphorylation of NAD to NADP YP_002444650.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002444651.1 identified by match to protein family HMM PF05658 YP_002444652.1 asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate YP_002444653.1 identified by match to protein family HMM PF01098 YP_002444654.1 identified by match to protein family HMM PF00535 YP_002444655.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002444656.1 identified by match to protein family HMM PF05711 YP_002444657.1 identified by match to protein family HMM PF01391 YP_002444658.1 identified by match to protein family HMM PF00535 YP_002444659.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002444660.1 identified by glimmer YP_002444662.1 identified by match to protein family HMM PF00483 YP_002444663.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_002444664.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002444665.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214 YP_002444666.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002444669.1 identified by match to protein family HMM PF07098 YP_002444670.1 identified by glimmer YP_002444671.1 identified by glimmer YP_002444673.1 identified by match to protein family HMM PF00580 YP_002444674.1 identified by match to protein family HMM PF00583 YP_002444675.1 similar to 2'-5' RNA ligase YP_002444676.1 identified by match to protein family HMM PF00756 YP_002444677.1 identified by match to protein family HMM PF00892 YP_002444678.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444679.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444681.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002444682.1 identified by glimmer YP_002444683.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002444684.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002444685.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002444686.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_002444687.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_002444688.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002444689.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002444692.1 identified by match to protein family HMM PF02652 YP_002444693.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002444696.1 identified by glimmer YP_002444699.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992 YP_002444700.1 identified by match to protein family HMM PF00583 YP_002444701.1 identified by glimmer YP_002444702.1 identified by match to protein family HMM TIGR03605 YP_002444703.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR03604 YP_002444704.1 identified by glimmer YP_002444705.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002444706.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002444707.1 identified by match to protein family HMM PF01381 YP_002444708.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444709.1 identified by glimmer YP_002444712.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444713.1 identified by match to protein family HMM PF00005 YP_002444718.1 identified by glimmer YP_002444719.1 identified by match to protein family HMM PF00768 YP_002444720.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02228 YP_002444724.1 identified by match to protein family HMM PF01381; match to protein family HMM PF08671 YP_002444725.1 identified by match to protein family HMM PF08671 YP_002444726.1 identified by match to protein family HMM PF05547; match to protein family HMM TIGR03296 YP_002444727.1 identified by match to protein family HMM PF00171 YP_002444728.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR01187 YP_002444729.1 identified by match to protein family HMM PF00528 YP_002444730.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF00528 YP_002444731.1 identified by match to protein family HMM PF01547 YP_002444732.1 identified by match to protein family HMM PF01569 YP_002444735.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002444736.1 identified by match to protein family HMM PF07853 YP_002444737.1 identified by match to protein family HMM PF00188; match to protein family HMM TIGR02909 YP_002444738.1 identified by match to protein family HMM PF02754 YP_002444739.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387 YP_002444740.1 identified by match to protein family HMM PF05651 YP_002444742.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444743.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002444744.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002444745.1 identified by match to protein family HMM PF02754 YP_002444746.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_002444747.1 identified by match to protein family HMM PF02589 YP_002444748.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_002444750.1 identified by match to protein family HMM PF01226 YP_002444751.1 identified by match to protein family HMM PF03741 YP_002444752.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002444753.1 identified by match to protein family HMM PF00269 YP_002444754.1 identified by match to protein family HMM PF01575 YP_002444755.1 identified by match to protein family HMM PF09602; match to protein family HMM TIGR02131 YP_002444756.1 identified by match to protein family HMM PF03551; match to protein family HMM TIGR02719 YP_002444757.1 identified by match to protein family HMM TIGR02132 YP_002444758.1 catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis YP_002444759.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR01836 YP_002444760.1 identified by match to protein family HMM PF01266 YP_002444761.1 identified by match to protein family HMM PF02386 YP_002444762.1 identified by glimmer YP_002444764.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR03261 YP_002444765.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03265 YP_002444766.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03262 YP_002444767.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002444768.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002444769.1 identified by match to protein family HMM PF03435 YP_002444770.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002444771.1 identified by glimmer YP_002444772.1 identified by match to protein family HMM PF00395; match to protein family HMM PF00560; match to protein family HMM PF05031 YP_002444773.1 identified by match to protein family HMM PF00596 YP_002444774.1 identified by match to protein family HMM PF00571 YP_002444775.1 identified by match to protein family HMM PF04748 YP_002444776.1 identified by match to protein family HMM PF09388 YP_002444777.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002444778.1 identified by match to protein family HMM PF01047 YP_002444779.1 identified by match to protein family HMM PF01432; match to protein family HMM TIGR02289 YP_002444781.1 identified by glimmer YP_002444782.1 identified by glimmer YP_002444783.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF07694 YP_002444784.1 identified by match to protein family HMM PF06508; match to protein family HMM TIGR00364 YP_002444785.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR03367 YP_002444786.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR03365 YP_002444787.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_002444789.1 identified by glimmer YP_002444790.1 identified by match to protein family HMM PF00300 YP_002444791.1 identified by match to protein family HMM PF00583 YP_002444793.1 identified by glimmer YP_002444794.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002444795.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002444796.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002444797.1 identified by match to protein family HMM PF00392 YP_002444798.1 identified by match to protein family HMM PF00005 YP_002444800.1 identified by match to protein family HMM PF00005 YP_002444802.1 identified by match to protein family HMM PF02517 YP_002444803.1 identified by glimmer YP_002444804.1 identified by match to protein family HMM PF01037 YP_002444805.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002444806.1 identified by match to protein family HMM PF00857 YP_002444808.1 identified by match to protein family HMM PF02016 YP_002444809.1 identified by match to protein family HMM PF03060 YP_002444810.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002444811.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_002444812.1 identified by match to protein family HMM PF03062 YP_002444813.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_002444814.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444815.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002444816.1 identified by glimmer YP_002444817.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002444818.1 identified by glimmer YP_002444819.1 identified by glimmer YP_002444820.1 identified by match to protein family HMM PF01636 YP_002444822.1 identified by glimmer YP_002444823.1 identified by glimmer YP_002444824.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002444825.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002444827.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002444828.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002444829.1 identified by match to protein family HMM PF01047 YP_002444830.1 identified by glimmer YP_002444831.1 identified by match to protein family HMM PF00375 YP_002444832.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002444834.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002444835.1 identified by glimmer YP_002444836.1 identified by match to protein family HMM PF03698 YP_002444837.1 identified by glimmer YP_002444838.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002444839.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002444840.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002444841.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002444842.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002444843.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002444844.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002444845.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002444846.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_002444847.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_002444848.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002444849.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_002444850.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002444851.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002444852.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002444853.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_002444854.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_002444855.1 catalyzes the formation of L-histidinol from L-histidinol phosphate YP_002444856.1 identified by glimmer YP_002444857.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002444858.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473 YP_002444859.1 identified by match to protein family HMM PF00884 YP_002444861.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048 YP_002444863.1 identified by match to protein family HMM PF01507; match to protein family HMM TIGR00434; match to protein family HMM TIGR02055 YP_002444864.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_002444865.1 identified by match to protein family HMM PF01583; match to protein family HMM TIGR00455 YP_002444866.1 identified by match to protein family HMM PF01077; match to protein family HMM PF03460 YP_002444867.1 identified by glimmer YP_002444868.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_002444869.1 identified by match to protein family HMM PF01903 YP_002444870.1 catalyzes the formation of siroheme from precorrin-2 YP_002444871.1 identified by match to protein family HMM PF00209 YP_002444873.1 identified by match to protein family HMM PF01551 YP_002444874.1 identified by match to protein family HMM PF00375 YP_002444875.1 identified by match to protein family HMM PF04167 YP_002444876.1 identified by match to protein family HMM PF03553 YP_002444878.1 identified by match to protein family HMM PF04012 YP_002444880.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002444881.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002444883.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002444884.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002444886.1 identified by glimmer YP_002444887.1 identified by match to protein family HMM PF02163 YP_002444889.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002444890.1 identified by match to protein family HMM PF00027 YP_002444891.1 identified by glimmer YP_002444892.1 identified by match to protein family HMM PF01925 YP_002444893.1 identified by match to protein family HMM PF01384 YP_002444894.1 identified by match to protein family HMM PF01865 YP_002444895.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002444897.1 identified by glimmer YP_002444898.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002444899.1 identified by match to protein family HMM PF01904 YP_002444900.1 identified by glimmer YP_002444901.1 identified by match to protein family HMM PF00589 YP_002444902.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002444903.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002444905.1 identified by match to protein family HMM PF03706; match to protein family HMM PF04329; match to protein family HMM PF04330; match to protein family HMM PF04331 YP_002444906.1 identified by glimmer YP_002444908.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002444909.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002444910.1 identified by match to protein family HMM PF07670 YP_002444911.1 identified by match to protein family HMM PF07670 YP_002444912.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002444913.1 catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c YP_002444914.1 identified by match to protein family HMM PF05140 YP_002444915.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR03144 YP_002444916.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002444917.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002444918.1 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636 YP_002444919.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_002444920.1 identified by glimmer YP_002444924.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614 YP_002444925.1 identified by match to protein family HMM PF02517 YP_002444926.1 identified by match to protein family HMM PF01476 YP_002444927.1 identified by match to protein family HMM PF00149 YP_002444928.1 identified by match to protein family HMM PF00376 YP_002444929.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002444930.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002444931.1 identified by glimmer YP_002444932.1 identified by glimmer YP_002444933.1 identified by match to protein family HMM PF01510 YP_002444934.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002444935.1 identified by match to protein family HMM PF00710 YP_002444936.1 identified by glimmer YP_002444937.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002444938.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002444939.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_002444940.1 identified by glimmer YP_002444944.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002444945.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002444949.1 identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836 YP_002444950.1 identified by match to protein family HMM PF00216 YP_002444951.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002444952.1 identified by match to protein family HMM PF07307 YP_002444953.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002444954.1 identified by match to protein family HMM PF00348; match to protein family HMM TIGR02748 YP_002444955.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002444956.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002444957.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002444958.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002444959.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07720 YP_002444960.1 identified by match to protein family HMM PF08858; match to protein family HMM PF08864 YP_002444962.1 identified by match to protein family HMM PF00355 YP_002444963.1 electron transport protein YP_002444964.1 identified by match to protein family HMM PF00034 YP_002444965.1 identified by match to protein family HMM PF07187 YP_002444966.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906 YP_002444967.1 identified by match to protein family HMM PF09577; match to protein family HMM TIGR02878 YP_002444968.1 identified by match to protein family HMM PF04298 YP_002444969.1 identified by match to protein family HMM PF03167 YP_002444970.1 identified by match to protein family HMM PF02588 YP_002444971.1 identified by match to protein family HMM PF03819 YP_002444972.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002444973.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002444974.1 identified by match to protein family HMM PF02585 YP_002444975.1 identified by match to protein family HMM PF00534 YP_002444976.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_002444977.1 identified by match to protein family HMM PF02237; match to protein family HMM PF03099; match to protein family HMM PF08279; match to protein family HMM TIGR00121 YP_002444979.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002444980.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002444981.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002444982.1 unwinds DNA YP_002444984.1 identified by match to protein family HMM PF03413 YP_002444985.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002444986.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002444987.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083 YP_002444989.1 identified by glimmer YP_002444990.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002444991.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_002444993.1 identified by glimmer YP_002444994.1 identified by glimmer YP_002444995.1 identified by match to protein family HMM PF08807 YP_002444999.1 identified by match to protein family HMM PF06908 YP_002445000.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544 YP_002445001.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02926 YP_002445002.1 identified by glimmer YP_002445004.1 identified by match to protein family HMM PF02074 YP_002445005.1 identified by match to protein family HMM PF00583 YP_002445006.1 identified by match to protein family HMM PF01636 YP_002445007.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002445008.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_002445009.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002445010.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002445011.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445012.1 identified by match to protein family HMM PF00350; match to protein family HMM PF01926 YP_002445013.1 identified by glimmer YP_002445014.1 identified by match to protein family HMM PF00583 YP_002445016.1 identified by match to protein family HMM PF00581 YP_002445017.1 identified by glimmer YP_002445019.1 identified by match to protein family HMM PF03738 YP_002445020.1 identified by match to protein family HMM PF03994 YP_002445022.1 identified by match to protein family HMM PF01367; match to protein family HMM PF02739 YP_002445024.1 identified by match to protein family HMM PF01757 YP_002445025.1 identified by match to protein family HMM PF02706 YP_002445027.1 identified by match to protein family HMM PF02397 YP_002445028.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002445029.1 identified by match to protein family HMM PF04932 YP_002445030.1 identified by match to protein family HMM PF00535 YP_002445031.1 identified by match to protein family HMM PF00534 YP_002445032.1 identified by glimmer YP_002445033.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451 YP_002445034.1 identified by match to protein family HMM PF00583 YP_002445035.1 identified by match to protein family HMM PF00857 YP_002445036.1 identified by glimmer YP_002445037.1 identified by match to protein family HMM PF00892 YP_002445038.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002445039.1 identified by match to protein family HMM PF01263 YP_002445040.1 identified by match to protein family HMM PF06177 YP_002445041.1 identified by match to protein family HMM PF00075 YP_002445044.1 identified by match to protein family HMM PF00313 YP_002445045.1 identified by glimmer YP_002445046.1 identified by match to protein family HMM PF08892 YP_002445047.1 identified by match to protein family HMM PF01810 YP_002445048.1 identified by glimmer YP_002445049.1 identified by match to protein family HMM PF04116 YP_002445050.1 identified by match to protein family HMM PF04341 YP_002445051.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813 YP_002445052.1 identified by match to protein family HMM PF00202 YP_002445053.1 identified by glimmer YP_002445054.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00932 YP_002445055.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002445056.1 identified by match to protein family HMM PF00376 YP_002445057.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002445058.1 identified by match to protein family HMM PF04239 YP_002445059.1 identified by match to protein family HMM PF02698 YP_002445061.1 identified by match to protein family HMM PF00665 YP_002445062.1 identified by match to protein family HMM PF01527 YP_002445063.1 identified by match to protein family HMM PF00881 YP_002445065.1 identified by match to protein family HMM PF01925 YP_002445066.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002445067.1 identified by match to protein family HMM PF09388 YP_002445068.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383 YP_002445069.1 identified by match to protein family HMM PF01966 YP_002445070.1 Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_002445071.1 Homolog to MotB, appears to be involved in motility on surfaces and under specific ionic conditions. With MotP (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002445072.1 identified by match to protein family HMM PF00072 YP_002445073.1 identified by match to protein family HMM PF01584; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF02895; match to protein family HMM PF07194 YP_002445074.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002445075.1 identified by glimmer YP_002445076.1 identified by glimmer YP_002445077.1 identified by match to protein family HMM PF01739; match to protein family HMM PF03705 YP_002445081.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002445082.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_002445083.1 involved in flagellin assembly YP_002445086.1 identified by glimmer YP_002445087.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_002445088.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002445089.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002445090.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002445091.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002445092.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002445093.1 involved in type III protein export during flagellum assembly YP_002445096.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod YP_002445097.1 the hook connects flagellar basal body to the flagellar filament YP_002445100.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584 YP_002445103.1 identified by match to protein family HMM PF00665 YP_002445104.1 identified by match to protein family HMM PF01527 YP_002445105.1 structural flagella protein YP_002445106.1 identified by match to protein family HMM PF01464 YP_002445107.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002445108.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002445109.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002445111.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002445112.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002445113.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_002445114.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002445115.1 membrane protein involved in the flagellar export apparatus YP_002445116.1 positive regulator of class III flagellar genes YP_002445117.1 makes up the distal portion of the flagellar basal body rod YP_002445119.1 identified by match to protein family HMM PF07973 YP_002445120.1 identified by match to protein family HMM PF01978 YP_002445121.1 identified by match to protein family HMM PF03591 YP_002445122.1 identified by match to protein family HMM PF05437 YP_002445123.1 identified by glimmer YP_002445124.1 identified by match to protein family HMM PF01738 YP_002445125.1 identified by match to protein family HMM PF03992 YP_002445126.1 identified by match to protein family HMM PF00535; match to protein family HMM PF07238 YP_002445127.1 identified by match to protein family HMM PF08141; match to protein family HMM TIGR02861 YP_002445128.1 identified by match to protein family HMM PF01381 YP_002445129.1 identified by match to protein family HMM PF07690 YP_002445131.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002445132.1 identified by match to protein family HMM PF00005 YP_002445133.1 identified by match to protein family HMM PF01547 YP_002445134.1 identified by match to protein family HMM PF00528 YP_002445135.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521 YP_002445138.1 identified by glimmer YP_002445139.1 identified by glimmer YP_002445142.1 identified by match to protein family HMM PF00300 YP_002445143.1 identified by glimmer YP_002445144.1 identified by match to protein family HMM PF00561 YP_002445146.1 identified by match to protein family HMM PF01047 YP_002445148.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 YP_002445149.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002445151.1 identified by match to protein family HMM PF02012 YP_002445152.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002445153.1 identified by glimmer YP_002445155.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002445156.1 identified by match to protein family HMM PF03773 YP_002445157.1 identified by match to protein family HMM PF09323 YP_002445159.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002445160.1 identified by match to protein family HMM PF00376 YP_002445161.1 identified by match to protein family HMM PF00106 YP_002445162.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002445163.1 identified by glimmer YP_002445166.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002445167.1 identified by match to protein family HMM PF03575 YP_002445168.1 identified by glimmer YP_002445169.1 identified by match to protein family HMM PF03965 YP_002445170.1 identified by match to protein family HMM PF01435; match to protein family HMM PF05569 YP_002445171.1 identified by match to protein family HMM PF02683 YP_002445172.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002445174.1 identified by glimmer YP_002445176.1 identified by glimmer YP_002445177.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002445178.1 catalyzes the formation of pyruvate from serine YP_002445179.1 identified by match to protein family HMM PF04286 YP_002445182.1 identified by glimmer YP_002445183.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in B. thuringiensis this protein is involved in beta-exotoxin I production YP_002445184.1 identified by glimmer YP_002445185.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002445186.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002445187.1 identified by match to protein family HMM PF00005 YP_002445188.1 identified by match to protein family HMM PF01061 YP_002445189.1 identified by match to protein family HMM PF01061 YP_002445190.1 identified by match to protein family HMM PF00614 YP_002445191.1 Catalyzes the phosphorylation of UMP to UDP YP_002445192.1 identified by match to protein family HMM PF00375 YP_002445193.1 catalyzes the formation of fumarate from aspartate YP_002445194.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002445195.1 identified by match to protein family HMM PF02518 YP_002445196.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08664 YP_002445197.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455 YP_002445200.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002445201.1 identified by match to protein family HMM PF00903 YP_002445202.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_002445206.1 identified by match to protein family HMM PF00293 YP_002445207.1 identified by match to protein family HMM PF07690 YP_002445209.1 identified by match to protein family HMM PF03976 YP_002445210.1 identified by match to protein family HMM PF03551 YP_002445211.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002445212.1 identified by match to protein family HMM PF07690 YP_002445213.1 FabH; beta-ketoacyl-ACP synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-ACP synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_002445214.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR03156 YP_002445215.1 identified by match to protein family HMM PF07690 YP_002445216.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002445217.1 identified by match to protein family HMM PF00583 YP_002445220.1 identified by match to protein family HMM PF00209 YP_002445221.1 identified by match to protein family HMM PF01522 YP_002445223.1 identified by match to protein family HMM PF04239 YP_002445224.1 identified by match to protein family HMM PF07299 YP_002445227.1 identified by glimmer YP_002445228.1 identified by match to protein family HMM PF01625; match to protein family HMM TIGR00401 YP_002445229.1 identified by match to protein family HMM PF00106 YP_002445230.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002445231.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002445232.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small subunit YP_002445233.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002445234.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002445235.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_002445236.1 identified by match to protein family HMM PF09587 YP_002445237.1 identified by match to protein family HMM PF04474 YP_002445238.1 identified by match to protein family HMM PF00583 YP_002445239.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002445240.1 identified by match to protein family HMM PF02900 YP_002445241.1 identified by match to protein family HMM PF00561 YP_002445242.1 identified by match to protein family HMM PF04397 YP_002445243.1 identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458 YP_002445244.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445245.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445246.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002445247.1 identified by match to protein family HMM PF00496 YP_002445248.1 identified by match to protein family HMM PF00583 YP_002445249.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002445250.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002445251.1 identified by match to protein family HMM PF01551 YP_002445252.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_002445253.1 identified by match to protein family HMM PF00581 YP_002445254.1 identified by glimmer YP_002445255.1 identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745 YP_002445258.1 identified by match to protein family HMM PF05791 YP_002445259.1 identified by match to protein family HMM PF05791 YP_002445260.1 identified by match to protein family HMM PF05791 YP_002445261.1 identified by match to protein family HMM PF02073 YP_002445262.1 identified by match to protein family HMM PF03403 YP_002445263.1 identified by glimmer YP_002445264.1 identified by match to protein family HMM PF00440 YP_002445265.1 identified by match to protein family HMM PF00583 YP_002445266.1 identified by match to protein family HMM PF01906 YP_002445267.1 identified by match to protein family HMM PF02517 YP_002445268.1 identified by match to protein family HMM PF00440 YP_002445269.1 identified by match to protein family HMM PF04198 YP_002445270.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002445271.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002445272.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002445273.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002445275.1 identified by match to protein family HMM PF00665 YP_002445277.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445282.1 identified by match to protein family HMM PF07301 YP_002445283.1 identified by match to protein family HMM PF05979 YP_002445284.1 identified by match to protein family HMM PF00557; match to protein family HMM PF05195 YP_002445285.1 identified by match to protein family HMM PF00805 YP_002445286.1 identified by match to protein family HMM PF00394; match to protein family HMM PF07731; match to protein family HMM PF07732 YP_002445288.1 decatenates replicating daughter chromosomes YP_002445290.1 identified by match to protein family HMM PF01758 YP_002445291.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002445292.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002445293.1 identified by match to protein family HMM PF00903 YP_002445294.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445295.1 identified by match to protein family HMM PF04234; match to protein family HMM PF05425 YP_002445296.1 identified by match to protein family HMM PF07987 YP_002445297.1 identified by match to protein family HMM PF00892 YP_002445298.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002445299.1 identified by match to protein family HMM PF02082 YP_002445300.1 identified by match to protein family HMM PF01323 YP_002445301.1 identified by match to protein family HMM PF00881 YP_002445303.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002445304.1 identified by glimmer YP_002445305.1 identified by match to protein family HMM PF01594 YP_002445306.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002445307.1 identified by match to protein family HMM PF01593 YP_002445308.1 identified by glimmer YP_002445309.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002445310.1 identified by match to protein family HMM PF01094 YP_002445311.1 identified by match to protein family HMM PF00005 YP_002445312.1 identified by match to protein family HMM PF00005 YP_002445313.1 identified by match to protein family HMM PF02653 YP_002445314.1 identified by match to protein family HMM PF02653 YP_002445315.1 identified by match to protein family HMM PF00126 YP_002445317.1 identified by match to protein family HMM PF05721 YP_002445318.1 identified by glimmer YP_002445319.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02623 YP_002445320.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR02622 YP_002445321.1 identified by match to protein family HMM PF00534 YP_002445322.1 identified by match to protein family HMM PF02277 YP_002445323.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002445324.1 identified by match to protein family HMM PF00501 YP_002445326.1 identified by match to protein family HMM PF00005 YP_002445327.1 identified by match to protein family HMM PF06182 YP_002445328.1 identified by match to protein family HMM PF06182 YP_002445329.1 identified by match to protein family HMM PF00535 YP_002445330.1 identified by match to protein family HMM PF02543 YP_002445331.1 identified by match to protein family HMM PF01947 YP_002445332.1 identified by glimmer YP_002445333.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03551 YP_002445334.1 identified by match to protein family HMM PF00296 YP_002445336.1 identified by match to protein family HMM PF01654 YP_002445337.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002445338.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02857 YP_002445339.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR02868 YP_002445341.1 identified by match to protein family HMM PF00535; match to protein family HMM PF08241 YP_002445342.1 identified by match to protein family HMM PF01041 YP_002445343.1 identified by match to protein family HMM PF00132 YP_002445344.1 identified by glimmer YP_002445348.1 identified by match to protein family HMM PF02016 YP_002445349.1 identified by match to protein family HMM PF00768 YP_002445350.1 identified by match to protein family HMM PF00881 YP_002445352.1 identified by match to protein family HMM PF00877; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002445353.1 identified by match to protein family HMM PF00561 YP_002445354.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002445355.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002445356.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002445357.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002445358.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF01596 YP_002445359.1 identified by match to protein family HMM PF04439 YP_002445360.1 identified by match to protein family HMM PF01522 YP_002445363.1 identified by match to protein family HMM PF01243 YP_002445364.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002445365.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002445366.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002445369.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002445370.1 identified by glimmer YP_002445371.1 identified by match to protein family HMM PF01522 YP_002445373.1 identified by match to protein family HMM PF02308 YP_002445374.1 identified by match to protein family HMM PF00583 YP_002445375.1 identified by match to protein family HMM PF04183 YP_002445376.1 identified by match to protein family HMM PF04183 YP_002445377.1 activates fatty acids by binding to coenzyme A YP_002445378.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_002445380.1 identified by match to protein family HMM PF01261 YP_002445381.1 identified by match to protein family HMM PF00269 YP_002445382.1 identified by match to protein family HMM PF07690 YP_002445383.1 identified by match to protein family HMM PF01810 YP_002445384.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002445386.1 identified by match to protein family HMM PF01734 YP_002445387.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002445388.1 identified by match to protein family HMM PF09234 YP_002445390.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002445391.1 identified by match to protein family HMM PF00293 YP_002445392.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002445393.1 identified by glimmer YP_002445394.1 identified by glimmer YP_002445395.1 identified by glimmer YP_002445396.1 identified by glimmer YP_002445397.1 identified by glimmer YP_002445398.1 identified by glimmer YP_002445399.1 identified by glimmer YP_002445400.1 identified by glimmer YP_002445402.1 identified by glimmer YP_002445403.1 identified by glimmer YP_002445406.1 identified by glimmer YP_002445407.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002445408.1 identified by match to protein family HMM PF04586; match to protein family HMM PF05065; match to protein family HMM TIGR01543; match to protein family HMM TIGR01554 YP_002445409.1 identified by glimmer YP_002445410.1 identified by glimmer YP_002445411.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002445412.1 identified by glimmer YP_002445413.1 identified by match to protein family HMM PF02687 YP_002445414.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002445415.1 identified by match to protein family HMM PF00082 YP_002445416.1 identified by match to protein family HMM PF01022 YP_002445417.1 identified by match to protein family HMM PF00248 YP_002445418.1 identified by match to protein family HMM PF07690 YP_002445421.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002445422.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002445423.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002445424.1 identified by glimmer YP_002445425.1 identified by glimmer YP_002445426.1 identified by match to protein family HMM PF03845 YP_002445427.1 identified by match to protein family HMM PF00210 YP_002445428.1 identified by glimmer YP_002445429.1 identified by glimmer YP_002445430.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558 YP_002445431.1 identified by glimmer YP_002445432.1 identified by match to protein family HMM PF01593 YP_002445433.1 identified by match to protein family HMM PF00583 YP_002445434.1 identified by match to protein family HMM PF00248 YP_002445435.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002445436.1 identified by match to protein family HMM PF00583 YP_002445437.1 identified by match to protein family HMM PF01297 YP_002445438.1 identified by glimmer YP_002445439.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01370 YP_002445440.1 catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds YP_002445441.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002445443.1 identified by match to protein family HMM PF00496 YP_002445444.1 catalyzes resistance to fosfomycin by the addition of a thiol cofactor YP_002445445.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445446.1 identified by match to protein family HMM PF00300 YP_002445447.1 identified by glimmer YP_002445448.1 identified by match to protein family HMM PF08757 YP_002445449.1 identified by match to protein family HMM PF00293 YP_002445450.1 identified by match to protein family HMM PF09335 YP_002445451.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002445452.1 identified by match to protein family HMM PF01544 YP_002445453.1 identified by match to protein family HMM PF03773 YP_002445454.1 identified by match to protein family HMM PF09323 YP_002445455.1 identified by match to protein family HMM PF03061 YP_002445456.1 identified by glimmer YP_002445457.1 identified by match to protein family HMM PF00614 YP_002445458.1 identified by match to protein family HMM PF07875 YP_002445460.1 identified by match to protein family HMM PF02254 YP_002445461.1 identified by match to protein family HMM PF04306 YP_002445462.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002445464.1 identified by match to protein family HMM PF00440 YP_002445466.1 identified by match to protein family HMM PF00571 YP_002445467.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002445468.1 identified by match to protein family HMM PF01588; match to protein family HMM TIGR02222 YP_002445469.1 identified by match to protein family HMM PF07609 YP_002445470.1 identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867 YP_002445471.1 identified by match to protein family HMM PF00583 YP_002445472.1 identified by match to protein family HMM PF02557 YP_002445473.1 identified by match to protein family HMM PF00293 YP_002445474.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002445475.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445476.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445477.1 identified by match to protein family HMM PF01957 YP_002445478.1 identified by match to protein family HMM PF01145 YP_002445479.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867 YP_002445480.1 identified by match to protein family HMM PF00300 YP_002445481.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002445482.1 identified by match to protein family HMM PF01047 YP_002445483.1 identified by match to protein family HMM PF07690 YP_002445485.1 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492 YP_002445486.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002445487.1 identified by match to protein family HMM PF00583 YP_002445489.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002445490.1 identified by match to protein family HMM PF02588 YP_002445491.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002445492.1 identified by match to protein family HMM PF00583 YP_002445493.1 identified by match to protein family HMM PF00149 YP_002445494.1 identified by match to protein family HMM PF07853 YP_002445495.1 identified by match to protein family HMM PF00583 YP_002445497.1 identified by match to protein family HMM PF00583 YP_002445499.1 identified by match to protein family HMM PF00583 YP_002445500.1 identified by match to protein family HMM PF06013 YP_002445503.1 identified by match to protein family HMM PF08817 YP_002445505.1 identified by match to protein family HMM PF01580 YP_002445507.1 identified by match to protein family HMM PF01764 YP_002445511.1 identified by glimmer YP_002445512.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002445513.1 identified by glimmer YP_002445517.1 identified by match to protein family HMM PF00583 YP_002445518.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002445520.1 identified by glimmer YP_002445521.1 identified by glimmer YP_002445523.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01209; match to protein family HMM PF05724; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002445524.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_002445526.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002445527.1 identified by match to protein family HMM PF01261 YP_002445528.1 identified by match to protein family HMM PF00903 YP_002445530.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002445531.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002445532.1 identified by glimmer YP_002445533.1 identified by match to protein family HMM PF03109 YP_002445534.1 identified by glimmer YP_002445535.1 identified by match to protein family HMM PF00753 YP_002445536.1 identified by glimmer YP_002445537.1 identified by match to protein family HMM PF00255 YP_002445538.1 identified by match to protein family HMM PF01841 YP_002445539.1 identified by match to protein family HMM PF01882 YP_002445540.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002445541.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002445542.1 identified by match to protein family HMM TIGR01660 YP_002445543.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002445544.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002445545.1 identified by match to protein family HMM PF00027; match to protein family HMM PF00325 YP_002445546.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002445547.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002445548.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002445549.1 identified by match to protein family HMM PF02391 YP_002445550.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002445551.1 identified by match to protein family HMM PF07690 YP_002445552.1 identified by match to protein family HMM PF03547 YP_002445554.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445555.1 catalyzes the formation of siroheme from precorrin-2 YP_002445556.1 identified by match to protein family HMM PF01903 YP_002445557.1 this protein contains the C-terminal section of uroporphyrinogen-III methyltransferase fused with uroporphyrinogen-III synthase; studies on Clostridium josui indicate that this protein has uroporphyrinogen-III methylase activity; functions in tetrapyrrole and heme biosynthesis YP_002445558.1 identified by match to protein family HMM PF00355; match to protein family HMM TIGR02378 YP_002445559.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_002445560.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04405 YP_002445561.1 identified by match to protein family HMM PF05901 YP_002445562.1 identified by glimmer YP_002445563.1 identified by glimmer YP_002445564.1 identified by match to protein family HMM PF00797 YP_002445565.1 identified by match to protein family HMM PF07819 YP_002445567.1 identified by match to protein family HMM PF04232 YP_002445568.1 identified by glimmer YP_002445570.1 identified by match to protein family HMM PF08863 YP_002445571.1 identified by match to protein family HMM PF00515 YP_002445574.1 identified by glimmer YP_002445575.1 identified by match to protein family HMM PF01966 YP_002445576.1 identified by match to protein family HMM PF00005 YP_002445577.1 identified by match to protein family HMM PF06539 YP_002445578.1 identified by glimmer YP_002445579.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002445580.1 identified by glimmer YP_002445582.1 identified by match to protein family HMM PF03130 YP_002445583.1 identified by glimmer YP_002445584.1 identified by match to protein family HMM PF06491 YP_002445586.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002445587.1 identified by glimmer YP_002445589.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002445590.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_002445591.1 identified by match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002445592.1 identified by glimmer YP_002445593.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002445594.1 identified by match to protein family HMM PF00209 YP_002445595.1 identified by match to protein family HMM PF00561 YP_002445596.1 identified by match to protein family HMM PF06042 YP_002445598.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002445599.1 identified by match to protein family HMM PF03600 YP_002445600.1 identified by match to protein family HMM PF00465 YP_002445601.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002445602.1 identified by match to protein family HMM PF01980 YP_002445603.1 identified by match to protein family HMM PF00583 YP_002445605.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445606.1 identified by match to protein family HMM TIGR01549; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662 YP_002445607.1 identified by match to protein family HMM PF00583 YP_002445608.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445609.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445612.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002445613.1 identified by match to protein family HMM PF00903 YP_002445614.1 identified by match to protein family HMM PF01636 YP_002445615.1 identified by match to protein family HMM PF00144 YP_002445616.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002445617.1 identified by match to protein family HMM PF00186 YP_002445618.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223 YP_002445619.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002445620.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002445621.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002445622.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002445623.1 identified by match to protein family HMM PF00902; match to protein family HMM TIGR00945 YP_002445625.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002445627.1 identified by glimmer YP_002445628.1 identified by match to protein family HMM PF02630 YP_002445629.1 identified by match to protein family HMM PF00011; match to protein family HMM PF04969 YP_002445630.1 identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 YP_002445631.1 identified by match to protein family HMM PF00583 YP_002445632.1 identified by glimmer YP_002445633.1 identified by match to protein family HMM PF01520; match to protein family HMM PF08239 YP_002445634.1 identified by match to protein family HMM PF01497 YP_002445635.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_002445636.1 identified by match to protein family HMM PF00881 YP_002445637.1 identified by glimmer YP_002445639.1 identified by match to protein family HMM PF00857 YP_002445640.1 identified by match to protein family HMM PF00293 YP_002445641.1 identified by match to protein family HMM PF00924 YP_002445642.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002445643.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002445644.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002445645.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002445646.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002445647.1 identified by match to protein family HMM PF00528 YP_002445648.1 identified by match to protein family HMM PF00528 YP_002445649.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01314 YP_002445650.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002445651.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_002445653.1 identified by match to protein family HMM PF00535 YP_002445655.1 identified by match to protein family HMM PF03358 YP_002445656.1 identified by match to protein family HMM PF07690 YP_002445657.1 identified by match to protein family HMM PF02698 YP_002445658.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01186 YP_002445659.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069 YP_002445660.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002445662.1 identified by match to protein family HMM PF07728 YP_002445663.1 identified by glimmer YP_002445664.1 identified by glimmer YP_002445665.1 remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions YP_002445666.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002445667.1 identified by match to protein family HMM PF00171 YP_002445668.1 identified by match to protein family HMM PF07997 YP_002445669.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00512; match to protein family HMM PF09385 YP_002445670.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02518 YP_002445672.1 identified by glimmer YP_002445673.1 identified by match to protein family HMM PF00202 YP_002445674.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429 YP_002445675.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428 YP_002445676.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_002445677.1 identified by match to protein family HMM PF00583 YP_002445678.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002445679.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_002445681.1 identified by match to protein family HMM PF06855 YP_002445683.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by glimmer YP_002445685.1 identified by glimmer YP_002445687.1 identified by match to protein family HMM PF07070 YP_002445688.1 identified by match to protein family HMM PF01569 YP_002445689.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002445690.1 identified by glimmer YP_002445691.1 identified by match to protein family HMM PF00085 YP_002445693.1 identified by glimmer YP_002445694.1 identified by glimmer YP_002445697.1 identified by match to protein family HMM PF01183 YP_002445698.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002445700.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002445701.1 identified by match to protein family HMM PF08863 YP_002445704.1 identified by match to protein family HMM PF00106 YP_002445706.1 identified by match to protein family HMM PF01679 YP_002445708.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002445709.1 identified by match to protein family HMM PF07690 YP_002445711.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration YP_002445712.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_002445713.1 identified by match to protein family HMM TIGR02317 YP_002445714.1 identified by glimmer YP_002445715.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002445716.1 identified by match to protein family HMM PF03446; match to protein family HMM PF03807 YP_002445717.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722 YP_002445718.1 identified by match to protein family HMM PF01810 YP_002445719.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_002445720.1 identified by glimmer YP_002445722.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00619 YP_002445723.1 identified by match to protein family HMM PF02463 YP_002445725.1 identified by match to protein family HMM PF01022 YP_002445727.1 identified by glimmer YP_002445728.1 identified by match to protein family HMM PF07690 YP_002445729.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_002445730.1 synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis YP_002445731.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR02275 YP_002445732.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857 YP_002445733.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733 YP_002445734.1 identified by match to protein family HMM PF03621 YP_002445735.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002445736.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00556 YP_002445738.1 identified by match to protein family HMM PF00216 YP_002445740.1 identified by match to protein family HMM PF05163 YP_002445741.1 identified by match to protein family HMM PF00082; match to protein family HMM PF05922 YP_002445742.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002445743.1 identified by glimmer YP_002445746.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002445747.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins YP_002445748.1 identified by match to protein family HMM PF00005 YP_002445749.1 identified by match to protein family HMM PF02687 YP_002445750.1 identified by match to protein family HMM PF02535 YP_002445751.1 identified by match to protein family HMM PF00753 YP_002445752.1 identified by match to protein family HMM PF01156 YP_002445753.1 identified by glimmer YP_002445755.1 identified by match to protein family HMM PF04657 YP_002445756.1 identified by match to protein family HMM PF00027 YP_002445757.1 identified by match to protein family HMM PF04657 YP_002445758.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00561 YP_002445759.1 identified by match to protein family HMM PF00583 YP_002445760.1 identified by match to protein family HMM PF00753 YP_002445761.1 identified by match to protein family HMM PF00440 YP_002445762.1 identified by match to protein family HMM PF03176 YP_002445763.1 identified by glimmer YP_002445764.1 identified by match to protein family HMM PF00302 YP_002445765.1 identified by match to protein family HMM PF00583 YP_002445766.1 identified by match to protein family HMM PF00583; match to protein family HMM PF00805 YP_002445767.1 identified by match to protein family HMM PF00583 YP_002445768.1 identified by match to protein family HMM PF00892 YP_002445769.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002445770.1 identified by glimmer YP_002445771.1 identified by glimmer YP_002445772.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_002445773.1 identified by glimmer YP_002445774.1 identified by match to protein family HMM PF00583 YP_002445776.1 identified by match to protein family HMM PF00313 YP_002445777.1 identified by match to protein family HMM PF02517 YP_002445780.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002445781.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002445782.1 identified by glimmer YP_002445783.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002445784.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002445785.1 identified by match to protein family HMM PF00583 YP_002445786.1 identified by match to protein family HMM PF07081 YP_002445787.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002445788.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002445789.1 identified by glimmer YP_002445790.1 identified by glimmer YP_002445791.1 identified by match to protein family HMM PF01810 YP_002445792.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002445794.1 identified by glimmer YP_002445795.1 identified by match to protein family HMM PF01391 YP_002445796.1 identified by match to protein family HMM PF01391 YP_002445797.1 identified by match to protein family HMM PF00190 YP_002445798.1 identified by glimmer YP_002445799.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01593 YP_002445800.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445801.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002445802.1 identified by glimmer YP_002445803.1 identified by match to protein family HMM PF01596 YP_002445804.1 identified by match to protein family HMM PF05816 YP_002445805.1 identified by glimmer YP_002445806.1 identified by match to protein family HMM PF02638 YP_002445807.1 identified by match to protein family HMM PF02302 YP_002445808.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002445810.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002445811.1 identified by match to protein family HMM PF01869 YP_002445812.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002445813.1 identified by match to protein family HMM PF00266 YP_002445814.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002445815.1 identified by match to protein family HMM PF01047 YP_002445816.1 identified by match to protein family HMM PF07690 YP_002445817.1 identified by match to protein family HMM PF06803 YP_002445818.1 identified by match to protein family HMM PF00753 YP_002445819.1 identified by glimmer YP_002445820.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002445821.1 identified by match to protein family HMM PF03848; match to protein family HMM PF05724; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002445822.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002445823.1 identified by match to protein family HMM PF08241 YP_002445824.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02775 YP_002445825.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445826.1 identified by match to protein family HMM PF01047 YP_002445827.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002445828.1 identified by glimmer YP_002445831.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002445832.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_002445835.1 identified by match to protein family HMM PF00196 YP_002445836.1 identified by match to protein family HMM PF01381 YP_002445837.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002445839.1 identified by match to protein family HMM PF01925 YP_002445840.1 identified by match to protein family HMM PF00132 YP_002445841.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002445842.1 identified by match to protein family HMM PF01757 YP_002445843.1 identified by match to protein family HMM PF00657 YP_002445844.1 identified by match to protein family HMM PF07690 YP_002445845.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733 YP_002445846.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733 YP_002445847.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733 YP_002445848.1 identified by match to protein family HMM PF01648; match to protein family HMM TIGR00556 YP_002445849.1 identified by match to protein family HMM PF00975 YP_002445850.1 identified by match to protein family HMM PF00106 YP_002445854.1 identified by glimmer YP_002445855.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445856.1 identified by glimmer YP_002445858.1 identified by match to protein family HMM PF00144 YP_002445861.1 identified by match to protein family HMM PF00583 YP_002445863.1 identified by match to protein family HMM PF00583 YP_002445864.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03446; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002445865.1 identified by match to protein family HMM PF01041; match to protein family HMM PF01212 YP_002445866.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002445867.1 identified by match to protein family HMM PF01041 YP_002445869.1 identified by match to protein family HMM PF08889 YP_002445870.1 identified by match to protein family HMM PF02585 YP_002445871.1 identified by match to protein family HMM PF01261 YP_002445872.1 identified by match to protein family HMM PF01546; match to protein family HMM PF04389 YP_002445873.1 identified by match to protein family HMM PF07690 YP_002445874.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445875.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445877.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002445879.1 identified by glimmer YP_002445880.1 identified by match to protein family HMM PF01022 YP_002445883.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01832 YP_002445884.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002445885.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002445887.1 identified by match to protein family HMM PF01522 YP_002445890.1 identified by glimmer YP_002445892.1 identified by glimmer YP_002445894.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223 YP_002445895.1 identified by glimmer YP_002445896.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002445897.1 identified by glimmer YP_002445898.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002445899.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002445900.1 identified by match to protein family HMM PF00144 YP_002445901.1 identified by match to protein family HMM PF00149 YP_002445902.1 identified by glimmer YP_002445903.1 identified by match to protein family HMM PF00005 YP_002445904.1 identified by match to protein family HMM PF01061 YP_002445905.1 identified by match to protein family HMM PF00440 YP_002445906.1 identified by glimmer YP_002445907.1 identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_002445908.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002445909.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002445910.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002445911.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_002445912.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002445913.1 identified by match to protein family HMM PF01039 YP_002445914.1 identified by match to protein family HMM PF00501 YP_002445915.1 identified by match to protein family HMM PF00665 YP_002445916.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445919.1 identified by match to protein family HMM PF00583 YP_002445920.1 identified by glimmer YP_002445921.1 identified by glimmer YP_002445922.1 identified by match to protein family HMM PF00768 YP_002445923.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002445924.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002445925.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488 YP_002445926.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445928.1 Enables the cleavage of the glycosidic bond in S-adenosylhomocysteine YP_002445929.1 identified by match to protein family HMM PF00583 YP_002445930.1 identified by glimmer YP_002445931.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504; match to protein family HMM TIGR01167 YP_002445932.1 identified by match to protein family HMM PF00165 YP_002445933.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002445934.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002445935.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002445936.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445937.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002445938.1 identified by match to protein family HMM PF08327 YP_002445939.1 identified by match to protein family HMM PF00005 YP_002445940.1 identified by match to protein family HMM PF00376; match to protein family HMM PF06445 YP_002445941.1 identified by match to protein family HMM PF00106 YP_002445942.1 identified by match to protein family HMM PF01638; match to protein family HMM PF03551 YP_002445943.1 identified by match to protein family HMM PF08241 YP_002445944.1 identified by match to protein family HMM PF00561 YP_002445946.1 identified by match to protein family HMM PF01636 YP_002445948.1 identified by match to protein family HMM PF00165 YP_002445949.1 identified by match to protein family HMM PF01432; match to protein family HMM TIGR02289 YP_002445950.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445951.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002445953.1 identified by glimmer YP_002445954.1 identified by glimmer YP_002445955.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF08240 YP_002445958.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002445959.1 identified by match to protein family HMM PF01965 YP_002445960.1 identified by match to protein family HMM PF03848; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002445961.1 identified by match to protein family HMM PF08450 YP_002445963.1 identified by match to protein family HMM PF01921; match to protein family HMM TIGR00467 YP_002445964.1 identified by match to protein family HMM PF07486 YP_002445965.1 identified by match to protein family HMM PF03069 YP_002445966.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002445967.1 identified by match to protein family HMM PF02518 YP_002445968.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002445969.1 identified by match to protein family HMM PF00248 YP_002445970.1 identified by match to protein family HMM PF00005 YP_002445971.1 identified by match to protein family HMM PF00583 YP_002445972.1 identified by match to protein family HMM PF00005 YP_002445973.1 identified by match to protein family HMM PF02687 YP_002445975.1 identified by glimmer YP_002445977.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002445978.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002445979.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002445980.1 identified by match to protein family HMM PF03070 YP_002445982.1 identified by match to protein family HMM TIGR03601 YP_002445985.1 identified by match to protein family HMM PF00589 YP_002445986.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445987.1 identified by glimmer YP_002445988.1 identified by glimmer YP_002445989.1 identified by match to protein family HMM PF01381 YP_002445990.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002445992.1 identified by match to protein family HMM TIGR01764 YP_002445994.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002445995.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002445996.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002445998.1 identified by glimmer YP_002445999.1 identified by match to protein family HMM PF08761 YP_002446001.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002446003.1 identified by match to protein family HMM PF07883 YP_002446004.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002446006.1 identified by glimmer YP_002446007.1 identified by match to protein family HMM TIGR01637 YP_002446008.1 identified by match to protein family HMM PF00589 YP_002446014.1 identified by match to protein family HMM PF01844 YP_002446015.1 identified by glimmer YP_002446017.1 identified by match to protein family HMM PF03354 YP_002446018.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002446019.1 identified by match to protein family HMM PF00574 YP_002446022.1 identified by match to protein family HMM TIGR01563 YP_002446025.1 identified by match to protein family HMM TIGR01603 YP_002446028.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446029.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446031.1 identified by match to protein family HMM TIGR01633 YP_002446032.1 identified by match to protein family HMM PF02018; match to protein family HMM TIGR01665 YP_002446033.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_002446034.1 identified by match to protein family HMM PF01510; match to protein family HMM PF08239 YP_002446037.1 identified by glimmer YP_002446039.1 identified by glimmer YP_002446042.1 identified by glimmer YP_002446043.1 identified by match to protein family HMM PF08874 YP_002446044.1 identified by glimmer YP_002446045.1 identified by match to protein family HMM PF00067 YP_002446046.1 identified by match to protein family HMM PF07690 YP_002446047.1 identified by match to protein family HMM PF00132 YP_002446048.1 identified by match to protein family HMM PF07561 YP_002446049.1 identified by match to protein family HMM PF03551 YP_002446050.1 identified by match to protein family HMM PF00067 YP_002446051.1 identified by match to protein family HMM PF05995 YP_002446052.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002446053.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002446054.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002446055.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002446056.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002446057.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002446058.1 identified by match to protein family HMM PF07155 YP_002446059.1 identified by match to protein family HMM PF00005 YP_002446060.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF02361 YP_002446061.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002446062.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF07694 YP_002446063.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446064.1 identified by glimmer YP_002446065.1 identified by glimmer YP_002446066.1 identified by glimmer YP_002446068.1 identified by glimmer YP_002446069.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446073.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446075.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02805 YP_002446076.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002446077.1 identified by match to protein family HMM PF00293 YP_002446080.1 identified by match to protein family HMM PF04229 YP_002446081.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002446082.1 identified by match to protein family HMM PF01569 YP_002446083.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002446084.1 identified by match to protein family HMM PF07690 YP_002446085.1 identified by match to protein family HMM PF00144 YP_002446086.1 identified by match to protein family HMM PF04892 YP_002446089.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002446090.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446091.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00376; match to protein family HMM PF08241 YP_002446092.1 identified by match to protein family HMM PF07690 YP_002446093.1 identified by glimmer YP_002446094.1 identified by match to protein family HMM PF00583 YP_002446095.1 identified by match to protein family HMM PF03009 YP_002446096.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446097.1 identified by match to protein family HMM PF02557; match to protein family HMM PF08239 YP_002446100.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002446101.1 identified by match to protein family HMM PF00892 YP_002446102.1 identified by match to protein family HMM PF01270 YP_002446103.1 identified by glimmer YP_002446104.1 identified by match to protein family HMM PF00583 YP_002446106.1 identified by match to protein family HMM PF00293 YP_002446107.1 identified by glimmer YP_002446108.1 identified by match to protein family HMM PF00144 YP_002446109.1 identified by glimmer YP_002446110.1 identified by match to protein family HMM PF07690 YP_002446111.1 identified by match to protein family HMM PF00583 YP_002446112.1 identified by match to protein family HMM PF00293 YP_002446113.1 binds the polymerase to DNA and acts as a sliding clamp YP_002446114.1 identified by match to protein family HMM PF00293 YP_002446115.1 identified by glimmer YP_002446118.1 identified by match to protein family HMM PF01042 YP_002446119.1 identified by match to protein family HMM PF09234 YP_002446120.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF09350 YP_002446121.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446122.1 identified by glimmer YP_002446124.1 identified by match to protein family HMM PF01734 YP_002446125.1 identified by match to protein family HMM PF08000 YP_002446126.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446127.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446129.1 identified by match to protein family HMM PF00583 YP_002446131.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002446132.1 identified by glimmer YP_002446133.1 identified by match to protein family HMM PF01541 YP_002446134.1 identified by match to protein family HMM PF00583 YP_002446135.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446137.1 identified by glimmer YP_002446138.1 identified by glimmer YP_002446140.1 identified by match to protein family HMM PF01609 YP_002446141.1 identified by match to protein family HMM PF00144 YP_002446142.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446143.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446144.1 identified by match to protein family HMM PF01609 YP_002446147.1 identified by match to protein family HMM PF00293 YP_002446148.1 identified by match to protein family HMM PF01266 YP_002446150.1 identified by match to protein family HMM PF00797 YP_002446151.1 identified by match to protein family HMM PF08877 YP_002446153.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002446154.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002446155.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002446156.1 identified by glimmer YP_002446157.1 identified by glimmer YP_002446158.1 identified by match to protein family HMM PF00005 YP_002446159.1 identified by match to protein family HMM PF02687 YP_002446161.1 identified by match to protein family HMM PF07859 YP_002446162.1 identified by match to protein family HMM PF00282; match to protein family HMM PF01212 YP_002446163.1 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08415; match to protein family HMM TIGR01733 YP_002446164.1 identified by match to protein family HMM TIGR03605 YP_002446165.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02806; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM TIGR02104 YP_002446166.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002446167.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002446168.1 identified by glimmer YP_002446170.1 identified by match to protein family HMM PF06445 YP_002446171.1 identified by match to protein family HMM PF00903 YP_002446172.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002446173.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_002446174.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002446175.1 identified by match to protein family HMM PF00561 YP_002446177.1 identified by glimmer YP_002446178.1 identified by glimmer YP_002446179.1 identified by match to protein family HMM PF08002 YP_002446180.1 identified by match to protein family HMM PF06081 YP_002446181.1 identified by match to protein family HMM PF00583 YP_002446183.1 identified by match to protein family HMM PF09580; match to protein family HMM TIGR02898 YP_002446184.1 identified by match to protein family HMM PF03413; match to protein family HMM TIGR02889 YP_002446185.1 identified by match to protein family HMM PF01471; match to protein family HMM PF07486; match to protein family HMM TIGR02869 YP_002446188.1 identified by match to protein family HMM PF00144 YP_002446189.1 identified by match to protein family HMM PF03301; match to protein family HMM TIGR03036 YP_002446190.1 identified by match to protein family HMM PF04199; match to protein family HMM TIGR03035 YP_002446191.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01814 YP_002446192.1 identified by match to protein family HMM PF00440 YP_002446193.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446194.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446195.1 identified by glimmer YP_002446196.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002446197.1 identified by glimmer YP_002446198.1 identified by glimmer YP_002446199.1 identified by match to protein family HMM PF00583 YP_002446200.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002446202.1 identified by match to protein family HMM PF03848; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002446203.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738 YP_002446205.1 identified by glimmer YP_002446206.1 E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002446207.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 YP_002446208.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002446209.1 identified by match to protein family HMM PF00676 YP_002446211.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002446212.1 identified by match to protein family HMM PF04229 YP_002446214.1 identified by match to protein family HMM PF00293 YP_002446216.1 identified by glimmer YP_002446217.1 identified by match to protein family HMM PF01230 YP_002446218.1 identified by glimmer YP_002446220.1 identified by match to protein family HMM PF00528 YP_002446221.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186 YP_002446222.1 identified by match to protein family HMM PF04069 YP_002446223.1 identified by match to protein family HMM PF00574; match to protein family HMM TIGR00493 YP_002446224.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002446225.1 identified by match to protein family HMM PF00111 YP_002446226.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002446227.1 identified by match to protein family HMM PF00583 YP_002446229.1 identified by glimmer YP_002446230.1 identified by match to protein family HMM PF00041; match to protein family HMM PF02839; match to protein family HMM PF03067 YP_002446231.1 identified by match to protein family HMM PF00201; match to protein family HMM PF04101; match to protein family HMM TIGR01426 YP_002446232.1 identified by match to protein family HMM PF03781 YP_002446233.1 In Listeria monocytogenes this protein binds a specific sites on DNA, influencing the topology and transcription; regulates flaA, proU and ompC; is osmoregulated YP_002446234.1 identified by match to protein family HMM PF01636 YP_002446236.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002446237.1 identified by match to protein family HMM PF04237 YP_002446238.1 identified by match to protein family HMM PF00583 YP_002446239.1 identified by match to protein family HMM PF00583 YP_002446240.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002446241.1 identified by glimmer YP_002446242.1 identified by match to protein family HMM PF00583 YP_002446244.1 identified by match to protein family HMM PF03551 YP_002446245.1 identified by match to protein family HMM PF06108 YP_002446247.1 identified by match to protein family HMM PF00583 YP_002446250.1 identified by match to protein family HMM PF06094 YP_002446251.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389 YP_002446252.1 identified by glimmer YP_002446254.1 identified by glimmer YP_002446255.1 identified by match to protein family HMM PF01183 YP_002446256.1 identified by match to protein family HMM PF01520 YP_002446259.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446260.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01432 YP_002446261.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002446262.1 identified by match to protein family HMM PF03067 YP_002446263.1 identified by match to protein family HMM PF00583 YP_002446264.1 identified by match to protein family HMM PF01966 YP_002446265.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002446266.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002446267.1 identified by match to protein family HMM PF00171 YP_002446268.1 identified by match to protein family HMM PF00701; match to protein family HMM TIGR00674 YP_002446269.1 identified by glimmer YP_002446270.1 identified by match to protein family HMM PF05544 YP_002446271.1 identified by match to protein family HMM PF01266 YP_002446272.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM TIGR00229 YP_002446273.1 identified by glimmer YP_002446274.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446275.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002446277.1 identified by glimmer YP_002446278.1 identified by match to protein family HMM PF08876 YP_002446279.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824 YP_002446280.1 identified by match to protein family HMM PF01966 YP_002446281.1 identified by match to protein family HMM PF09335 YP_002446282.1 identified by glimmer YP_002446283.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002446284.1 identified by match to protein family HMM PF00496 YP_002446285.1 identified by match to protein family HMM PF00877 YP_002446286.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002446288.1 identified by match to protein family HMM PF04977 YP_002446289.1 identified by match to protein family HMM PF00248 YP_002446290.1 identified by match to protein family HMM PF01965 YP_002446291.1 identified by match to protein family HMM PF00023 YP_002446293.1 identified by glimmer YP_002446295.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002446296.1 identified by match to protein family HMM PF08530 YP_002446297.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002446298.1 identified by glimmer YP_002446299.1 identified by glimmer YP_002446301.1 identified by match to protein family HMM PF01580 YP_002446304.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446305.1 identified by match to protein family HMM PF01381 YP_002446309.1 identified by glimmer YP_002446311.1 identified by match to protein family HMM PF07693 YP_002446312.1 identified by match to protein family HMM PF01510 YP_002446315.1 identified by match to protein family HMM TIGR01665 YP_002446316.1 identified by match to protein family HMM TIGR01633 YP_002446317.1 identified by match to protein family HMM TIGR01760 YP_002446321.1 identified by glimmer YP_002446322.1 identified by match to protein family HMM TIGR02126 YP_002446329.1 identified by glimmer YP_002446333.1 identified by match to protein family HMM TIGR01630 YP_002446335.1 identified by glimmer YP_002446337.1 identified by glimmer YP_002446338.1 identified by glimmer YP_002446340.1 identified by glimmer YP_002446342.1 identified by match to protein family HMM PF04014 YP_002446344.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446345.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446348.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF02129 YP_002446349.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002446350.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002446351.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002446352.1 identified by glimmer YP_002446353.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446354.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446355.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002446356.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002446357.1 identified by match to protein family HMM PF01432 YP_002446358.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002446359.1 identified by match to protein family HMM PF07552 YP_002446361.1 identified by match to protein family HMM PF07552 YP_002446362.1 identified by match to protein family HMM PF00583 YP_002446363.1 identified by match to protein family HMM PF00583 YP_002446365.1 identified by glimmer YP_002446366.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002446368.1 identified by match to protein family HMM PF04519 YP_002446370.1 identified by match to protein family HMM PF00496 YP_002446371.1 identified by match to protein family HMM PF07690 YP_002446373.1 identified by glimmer YP_002446374.1 identified by glimmer YP_002446375.1 identified by match to protein family HMM PF04226 YP_002446376.1 identified by match to protein family HMM PF01156 YP_002446377.1 identified by glimmer YP_002446378.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002446379.1 identified by glimmer YP_002446380.1 identified by glimmer YP_002446381.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446382.1 identified by glimmer YP_002446383.1 identified by match to protein family HMM PF07690 YP_002446384.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002446386.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002446387.1 identified by match to protein family HMM PF07977 YP_002446388.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_002446392.1 identified by match to protein family HMM PF00005 YP_002446393.1 identified by match to protein family HMM PF00392 YP_002446396.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002446397.1 identified by match to protein family HMM TIGR02413 YP_002446398.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002446399.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002446400.1 identified by match to protein family HMM PF09501; match to protein family HMM TIGR02413 YP_002446401.1 identified by match to protein family HMM PF01594 YP_002446402.1 identified by glimmer YP_002446403.1 catalyzes the release of sulfite from alkanesulfonates YP_002446404.1 identified by match to protein family HMM PF00528 YP_002446405.1 identified by match to protein family HMM PF04069; match to protein family HMM PF09084; match to protein family HMM TIGR01728 YP_002446406.1 identified by match to protein family HMM PF00005 YP_002446407.1 identified by match to protein family HMM PF04167 YP_002446409.1 identified by match to protein family HMM PF07719 YP_002446410.1 identified by match to protein family HMM PF04127 YP_002446411.1 identified by match to protein family HMM PF02522 YP_002446412.1 identified by match to protein family HMM PF00583 YP_002446414.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446415.1 identified by match to protein family HMM PF00583 YP_002446416.1 identified by match to protein family HMM PF00583 YP_002446418.1 identified by match to protein family HMM PF06352 YP_002446419.1 identified by match to protein family HMM PF00291 YP_002446420.1 identified by match to protein family HMM PF00903 YP_002446423.1 identified by match to protein family HMM PF01522 YP_002446426.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446427.1 identified by match to protein family HMM PF03741 YP_002446428.1 identified by match to protein family HMM PF00884 YP_002446429.1 identified by match to protein family HMM PF00005 YP_002446430.1 identified by match to protein family HMM PF03176 YP_002446431.1 identified by match to protein family HMM PF00440 YP_002446432.1 identified by match to protein family HMM PF00583 YP_002446433.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002446434.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_002446435.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002446436.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002446437.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_002446440.1 identified by match to protein family HMM PF00857 YP_002446441.1 identified by match to protein family HMM PF00583 YP_002446442.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446444.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002446447.1 identified by glimmer YP_002446448.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446449.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446450.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002446452.1 identified by match to protein family HMM PF02653 YP_002446453.1 identified by match to protein family HMM PF02653 YP_002446454.1 identified by match to protein family HMM PF00005 YP_002446455.1 identified by match to protein family HMM PF04198 YP_002446456.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002446457.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF07883 YP_002446458.1 identified by match to protein family HMM PF01791 YP_002446460.1 identified by match to protein family HMM PF00903 YP_002446461.1 identified by match to protein family HMM PF03992 YP_002446462.1 identified by match to protein family HMM PF07690 YP_002446463.1 identified by match to protein family HMM PF01022 YP_002446464.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM TIGR00804 YP_002446465.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002446466.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002446467.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002446468.1 identified by match to protein family HMM PF01546 YP_002446469.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002446470.1 identified by match to protein family HMM PF00324 YP_002446471.1 identified by glimmer YP_002446473.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446475.1 identified by match to protein family HMM PF00487 YP_002446476.1 identified by glimmer YP_002446477.1 identified by match to protein family HMM PF05547; match to protein family HMM TIGR03296 YP_002446478.1 identified by match to protein family HMM PF04294 YP_002446479.1 identified by match to protein family HMM PF00245 YP_002446483.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002446484.1 Phosphoprylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway YP_002446485.1 identified by match to protein family HMM PF00583 YP_002446486.1 identified by match to protein family HMM PF00903 YP_002446487.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446489.1 identified by match to protein family HMM PF03551 YP_002446490.1 identified by match to protein family HMM PF07726; match to protein family HMM PF07728 YP_002446491.1 identified by match to protein family HMM PF01882 YP_002446493.1 identified by glimmer YP_002446495.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002446496.1 identified by match to protein family HMM PF00202 YP_002446497.1 identified by match to protein family HMM PF00199 YP_002446499.1 identified by match to protein family HMM PF01979 YP_002446500.1 identified by match to protein family HMM PF00144 YP_002446501.1 identified by glimmer YP_002446504.1 identified by match to protein family HMM PF08928; match to protein family HMM PF08929 YP_002446506.1 identified by match to protein family HMM PF08928; match to protein family HMM PF08929 YP_002446510.1 identified by match to protein family HMM PF03992 YP_002446511.1 identified by match to protein family HMM PF00881 YP_002446512.1 identified by match to protein family HMM PF01047 YP_002446513.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM PF08477; match to protein family HMM TIGR00231 YP_002446515.1 identified by match to protein family HMM PF00293 YP_002446516.1 identified by match to protein family HMM PF05406 YP_002446517.1 identified by match to protein family HMM PF01370 YP_002446518.1 identified by match to protein family HMM PF00005 YP_002446519.1 identified by match to protein family HMM PF02687 YP_002446520.1 identified by match to protein family HMM PF02687 YP_002446521.1 identified by glimmer YP_002446522.1 identified by glimmer YP_002446523.1 identified by match to protein family HMM PF00144 YP_002446524.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002446525.1 identified by match to protein family HMM PF00583 YP_002446526.1 identified by glimmer YP_002446527.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00293 YP_002446528.1 identified by match to protein family HMM PF00892 YP_002446529.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002446530.1 identified by match to protein family HMM PF02639 YP_002446532.1 identified by glimmer YP_002446534.1 phosphorylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway YP_002446535.1 identified by match to protein family HMM PF00149 YP_002446536.1 identified by match to protein family HMM PF01636 YP_002446538.1 identified by match to protein family HMM PF01925 YP_002446539.1 identified by match to protein family HMM PF00583 YP_002446540.1 identified by match to protein family HMM PF00324 YP_002446542.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446543.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446544.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446545.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446546.1 identified by match to protein family HMM PF01156 YP_002446547.1 identified by glimmer YP_002446550.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446551.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446552.1 identified by match to protein family HMM PF02559 YP_002446553.1 identified by glimmer YP_002446554.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF03405 YP_002446556.1 identified by glimmer YP_002446557.1 identified by match to protein family HMM PF08241 YP_002446558.1 identified by match to protein family HMM PF00293 YP_002446559.1 identified by match to protein family HMM PF04989 YP_002446560.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002446561.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002446562.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002446563.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002446564.1 identified by match to protein family HMM PF06166 YP_002446565.1 identified by match to protein family HMM PF06149 YP_002446566.1 identified by match to protein family HMM PF03746 YP_002446567.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_002446568.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_002446569.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002446570.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002446571.1 identified by match to protein family HMM PF03932 YP_002446572.1 identified by match to protein family HMM PF01022 YP_002446573.1 identified by glimmer YP_002446574.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028 YP_002446575.1 identified by match to protein family HMM PF02698 YP_002446577.1 identified by match to protein family HMM PF00583 YP_002446578.1 identified by match to protein family HMM PF07670 YP_002446579.1 identified by match to protein family HMM PF01636 YP_002446580.1 identified by match to protein family HMM PF00583 YP_002446583.1 identified by match to protein family HMM PF00583 YP_002446584.1 identified by match to protein family HMM PF01061 YP_002446585.1 identified by match to protein family HMM PF00440 YP_002446586.1 identified by match to protein family HMM PF00391; match to protein family HMM PF01326 YP_002446587.1 identified by glimmer YP_002446588.1 identified by match to protein family HMM PF00753 YP_002446591.1 identified by match to protein family HMM PF00269 YP_002446592.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002446593.1 identified by match to protein family HMM PF05067 YP_002446594.1 catalyzes the formation of fumarate from aspartate YP_002446595.1 identified by match to protein family HMM PF00710; match to protein family HMM TIGR00519 YP_002446596.1 identified by match to protein family HMM PF01381 YP_002446598.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002446599.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002446600.1 identified by match to protein family HMM PF03323 YP_002446601.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002446602.1 identified by match to protein family HMM PF05791 YP_002446603.1 identified by match to protein family HMM PF05791 YP_002446604.1 identified by match to protein family HMM PF05791 YP_002446605.1 identified by match to protein family HMM PF05791 YP_002446606.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00165 YP_002446607.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446608.1 identified by glimmer YP_002446609.1 identified by match to protein family HMM PF01541 YP_002446610.1 identified by match to protein family HMM PF00324; match to protein family HMM PF03845 YP_002446611.1 identified by match to protein family HMM PF03807 YP_002446612.1 identified by glimmer YP_002446613.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002446614.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002446615.1 identified by match to protein family HMM PF03323 YP_002446616.1 identified by glimmer YP_002446617.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08664 YP_002446618.1 identified by match to protein family HMM PF02518 YP_002446619.1 catalyzes the formation of glutamate from glutamine YP_002446620.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002446621.1 identified by match to protein family HMM PF03600 YP_002446623.1 identified by match to protein family HMM PF00144 YP_002446625.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002446626.1 identified by match to protein family HMM PF00561 YP_002446627.1 identified by match to protein family HMM PF00857 YP_002446628.1 identified by match to protein family HMM PF00857 YP_002446630.1 identified by match to protein family HMM PF07969 YP_002446631.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002446632.1 identified by match to protein family HMM PF01047 YP_002446633.1 identified by match to protein family HMM PF01544 YP_002446638.1 identified by match to protein family HMM TIGR01655 YP_002446640.1 identified by match to protein family HMM PF03073 YP_002446641.1 identified by match to protein family HMM PF00875; match to protein family HMM PF03441 YP_002446642.1 identified by match to protein family HMM PF00484 YP_002446644.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002446646.1 identified by match to protein family HMM PF01522 YP_002446647.1 identified by match to protein family HMM PF00583 YP_002446648.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002446649.1 identified by match to protein family HMM PF01297 YP_002446650.1 identified by match to protein family HMM PF00950 YP_002446651.1 identified by match to protein family HMM PF00005 YP_002446652.1 identified by match to protein family HMM PF01965 YP_002446654.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_002446655.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832 YP_002446656.1 identified by match to protein family HMM PF00903 YP_002446657.1 identified by match to protein family HMM PF01022 YP_002446659.1 identified by match to protein family HMM PF01965 YP_002446660.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002446661.1 identified by glimmer YP_002446662.1 identified by match to protein family HMM PF07690 YP_002446663.1 identified by match to protein family HMM PF00892 YP_002446665.1 identified by match to protein family HMM PF01609 YP_002446667.1 identified by match to protein family HMM PF01609 YP_002446670.1 identified by glimmer YP_002446671.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002446672.1 identified by match to protein family HMM PF00440 YP_002446673.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002446674.1 identified by match to protein family HMM PF01037 YP_002446675.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002446677.1 identified by match to protein family HMM PF00903 YP_002446679.1 identified by match to protein family HMM PF00144 YP_002446680.1 identified by match to protein family HMM PF03413 YP_002446682.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002446683.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002446684.1 identified by glimmer YP_002446686.1 identified by match to protein family HMM PF02517 YP_002446687.1 identified by match to protein family HMM PF05139 YP_002446689.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002446690.1 identified by match to protein family HMM PF01565; match to protein family HMM PF08031 YP_002446691.1 identified by match to protein family HMM PF02687 YP_002446692.1 identified by match to protein family HMM PF00005 YP_002446693.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002446694.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002446695.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00905 YP_002446696.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446697.1 identified by glimmer YP_002446699.1 identified by match to protein family HMM PF00067; match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00667 YP_002446700.1 identified by glimmer YP_002446701.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002446702.1 identified by glimmer YP_002446704.1 catalyzes the formation of pyruvate from D-cysteine YP_002446705.1 identified by match to protein family HMM PF00149 YP_002446707.1 identified by match to protein family HMM PF06161 YP_002446708.1 identified by match to protein family HMM PF02409; match to protein family HMM TIGR00027 YP_002446710.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002446711.1 identified by match to protein family HMM PF00005 YP_002446712.1 identified by match to protein family HMM PF02687 YP_002446713.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002446714.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002446715.1 identified by match to protein family HMM PF02588 YP_002446716.1 identified by match to protein family HMM PF01047 YP_002446717.1 identified by match to protein family HMM PF00583 YP_002446718.1 identified by match to protein family HMM PF04299 YP_002446719.1 identified by match to protein family HMM PF02588 YP_002446720.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002446721.1 identified by glimmer YP_002446722.1 identified by match to protein family HMM PF02016 YP_002446725.1 identified by match to protein family HMM PF06245 YP_002446726.1 identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826 YP_002446727.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002446730.1 identified by match to protein family HMM PF07883 YP_002446731.1 identified by match to protein family HMM PF00165 YP_002446732.1 identified by glimmer YP_002446733.1 identified by match to protein family HMM PF01804 YP_002446735.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002446736.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01510; match to protein family HMM PF08239 YP_002446737.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446738.1 identified by match to protein family HMM PF00440 YP_002446739.1 identified by match to protein family HMM PF07690 YP_002446745.1 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741 YP_002446746.1 identified by match to protein family HMM PF06352 YP_002446749.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446750.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446753.1 identified by glimmer YP_002446754.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446755.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446756.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446759.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002446765.1 identified by match to protein family HMM PF09346 YP_002446767.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446768.1 identified by glimmer YP_002446769.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741 YP_002446771.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741 YP_002446772.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446773.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_002446774.1 identified by match to protein family HMM PF00239 YP_002446781.1 identified by match to protein family HMM PF02557 YP_002446782.1 identified by match to protein family HMM PF09587 YP_002446784.1 identified by match to protein family HMM PF07690 YP_002446786.1 identified by match to protein family HMM PF00561 YP_002446787.1 identified by match to protein family HMM PF01047 YP_002446788.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002446789.1 identified by match to protein family HMM PF00144 YP_002446790.1 identified by glimmer YP_002446791.1 identified by glimmer YP_002446792.1 identified by match to protein family HMM PF02667; match to protein family HMM PF03806 YP_002446793.1 identified by glimmer YP_002446794.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002446795.1 identified by match to protein family HMM PF04434 YP_002446800.1 identified by match to protein family HMM PF00005 YP_002446801.1 identified by match to protein family HMM PF02361 YP_002446803.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM TIGR01167 YP_002446804.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446805.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002446806.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03606; match to protein family HMM PF03806 YP_002446807.1 identified by match to protein family HMM PF04231 YP_002446808.1 identified by glimmer YP_002446809.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01048 YP_002446810.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_002446811.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002446813.1 identified by glimmer YP_002446814.1 identified by match to protein family HMM PF01638 YP_002446815.1 identified by match to protein family HMM PF00881 YP_002446817.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002446821.1 identified by glimmer YP_002446822.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002446824.1 identified by match to protein family HMM PF00005 YP_002446825.1 identified by glimmer YP_002446826.1 identified by glimmer YP_002446827.1 identified by match to protein family HMM PF01381 YP_002446829.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002446832.1 identified by match to protein family HMM PF00583 YP_002446834.1 identified by match to protein family HMM PF00293 YP_002446836.1 identified by match to protein family HMM PF00903 YP_002446837.1 identified by match to protein family HMM PF00480 YP_002446838.1 identified by match to protein family HMM PF07690 YP_002446839.1 identified by match to protein family HMM PF00132 YP_002446840.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002446841.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002446842.1 identified by match to protein family HMM PF01594 YP_002446843.1 identified by match to protein family HMM PF04226 YP_002446844.1 identified by match to protein family HMM PF00583 YP_002446845.1 identified by glimmer YP_002446846.1 identified by match to protein family HMM PF01391 YP_002446847.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by match to protein family HMM PF01391 YP_002446848.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446849.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002446850.1 identified by match to protein family HMM PF07336 YP_002446851.1 identified by match to protein family HMM PF07690 YP_002446852.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002446854.1 identified by glimmer YP_002446857.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002446859.1 identified by match to protein family HMM PF00892 YP_002446860.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446861.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002446862.1 identified by match to protein family HMM PF00805 YP_002446863.1 identified by match to protein family HMM PF06906 YP_002446865.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01314 YP_002446866.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_002446867.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_002446868.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002446869.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002446870.1 identified by match to protein family HMM PF03928 YP_002446871.1 identified by match to protein family HMM PF06993 YP_002446872.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222 YP_002446874.1 identified by match to protein family HMM PF08858 YP_002446875.1 identified by match to protein family HMM PF02082 YP_002446877.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002446878.1 identified by match to protein family HMM PF01638 YP_002446879.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002446880.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002446882.1 identified by match to protein family HMM PF00082 YP_002446883.1 identified by match to protein family HMM PF00657 YP_002446884.1 identified by match to protein family HMM PF00753 YP_002446887.1 identified by match to protein family HMM PF01784 YP_002446888.1 identified by glimmer YP_002446889.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002446890.1 identified by match to protein family HMM PF00583 YP_002446891.1 identified by match to protein family HMM PF00501 YP_002446892.1 identified by match to protein family HMM PF02525 YP_002446893.1 identified by match to protein family HMM PF01638 YP_002446894.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494 YP_002446896.1 identified by match to protein family HMM PF01022 YP_002446897.1 identified by match to protein family HMM PF00535; match to protein family HMM PF00704; match to protein family HMM PF01522; match to protein family HMM PF03142 YP_002446899.1 Heat shock-induced YP_002446901.1 identified by glimmer YP_002446902.1 identified by match to protein family HMM PF06445 YP_002446903.1 identified by match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002446904.1 identified by match to protein family HMM PF01061 YP_002446905.1 identified by match to protein family HMM PF00005 YP_002446906.1 identified by match to protein family HMM PF06304 YP_002446907.1 identified by match to protein family HMM PF03551 YP_002446908.1 identified by match to protein family HMM PF00668 YP_002446909.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002446913.1 identified by glimmer YP_002446914.1 identified by match to protein family HMM PF00144 YP_002446915.1 identified by glimmer YP_002446918.1 identified by match to protein family HMM PF00027 YP_002446919.1 identified by match to protein family HMM PF04657 YP_002446920.1 identified by match to protein family HMM PF04657 YP_002446921.1 identified by glimmer YP_002446922.1 identified by match to protein family HMM PF00753 YP_002446923.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02817 YP_002446924.1 identified by match to protein family HMM PF00324 YP_002446925.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_002446928.1 identified by glimmer YP_002446929.1 identified by match to protein family HMM PF00106 YP_002446930.1 identified by match to protein family HMM PF02585 YP_002446931.1 identified by match to protein family HMM PF08830 YP_002446932.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002446933.1 identified by glimmer YP_002446934.1 identified by match to protein family HMM PF00583 YP_002446935.1 identified by glimmer YP_002446936.1 identified by match to protein family HMM PF01497 YP_002446937.1 identified by match to protein family HMM PF01032 YP_002446938.1 identified by match to protein family HMM PF01032 YP_002446939.1 identified by match to protein family HMM PF05675 YP_002446942.1 identified by match to protein family HMM PF05163 YP_002446945.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002446946.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002446947.1 identified by match to protein family HMM PF00300 YP_002446948.1 identified by match to protein family HMM PF00583 YP_002446949.1 identified by match to protein family HMM PF00078; match to protein family HMM PF01348 YP_002446950.1 identified by glimmer YP_002446951.1 identified by match to protein family HMM PF00488 YP_002446953.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002446954.1 identified by match to protein family HMM PF00797 YP_002446955.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002446956.1 identified by match to protein family HMM PF04371 YP_002446957.1 identified by match to protein family HMM PF06445 YP_002446958.1 identified by match to protein family HMM PF04371 YP_002446959.1 identified by match to protein family HMM PF06146 YP_002446960.1 identified by match to protein family HMM PF04371 YP_002446961.1 identified by match to protein family HMM PF00144 YP_002446963.1 identified by match to protein family HMM PF07690 YP_002446964.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002446965.1 identified by glimmer YP_002446966.1 identified by match to protein family HMM PF03009 YP_002446967.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494 YP_002446969.1 identified by match to protein family HMM PF01022 YP_002446970.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002446971.1 identified by match to protein family HMM PF02696 YP_002446973.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07720 YP_002446975.1 identified by match to protein family HMM PF01758 YP_002446976.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002446978.1 identified by match to protein family HMM PF00583 YP_002446979.1 identified by match to protein family HMM PF00581; match to protein family HMM PF00753 YP_002446980.1 identified by match to protein family HMM PF07992 YP_002446984.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446985.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002446986.1 identified by glimmer YP_002446987.1 identified by match to protein family HMM PF03102; match to protein family HMM PF08666; match to protein family HMM TIGR03586 YP_002446988.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR03585 YP_002446989.1 identified by match to protein family HMM PF04101; match to protein family HMM TIGR03590 YP_002446990.1 identified by match to protein family HMM PF02348; match to protein family HMM PF08666 YP_002446991.1 identified by match to protein family HMM PF01041; match to protein family HMM PF01212; match to protein family HMM TIGR03588 YP_002446992.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002446993.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993 YP_002446994.1 identified by match to protein family HMM PF05159 YP_002446995.1 identified by match to protein family HMM PF00535 YP_002446996.1 identified by match to protein family HMM PF00535 YP_002446998.1 identified by match to protein family HMM PF00388 YP_002446999.1 identified by match to protein family HMM PF00041; match to protein family HMM PF02839; match to protein family HMM PF03067 YP_002447000.1 identified by glimmer YP_002447002.1 identified by match to protein family HMM PF03323 YP_002447003.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002447004.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002447005.1 identified by match to protein family HMM PF08795 YP_002447006.1 identified by match to protein family HMM PF00483 YP_002447008.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002447009.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM TIGR02622 YP_002447010.1 identified by match to protein family HMM PF00515 YP_002447011.1 identified by glimmer YP_002447012.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; match to protein family HMM PF02743 YP_002447013.1 identified by glimmer YP_002447017.1 identified by match to protein family HMM PF00150 YP_002447018.1 identified by glimmer YP_002447019.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447020.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002447021.1 identified by match to protein family HMM PF00005 YP_002447022.1 identified by match to protein family HMM PF00440 YP_002447023.1 identified by match to protein family HMM PF07968; match to protein family HMM TIGR01002 YP_002447024.1 identified by match to protein family HMM PF00395; match to protein family HMM PF01520 YP_002447025.1 identified by match to protein family HMM PF02557 YP_002447027.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002447029.1 identified by glimmer YP_002447030.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002447031.1 identified by match to protein family HMM PF00801; match to protein family HMM PF01752; match to protein family HMM PF04151; match to protein family HMM PF08453 YP_002447032.1 identified by match to protein family HMM PF02308 YP_002447033.1 identified by match to protein family HMM PF00583 YP_002447034.1 identified by match to protein family HMM PF00903 YP_002447035.1 identified by match to protein family HMM PF04294 YP_002447036.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447037.1 identified by glimmer YP_002447039.1 identified by glimmer YP_002447040.1 has 3'-5' exonuclease activity YP_002447041.1 identified by match to protein family HMM PF00313 YP_002447043.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002447045.1 identified by match to protein family HMM PF00293 YP_002447046.1 identified by match to protein family HMM PF04266 YP_002447048.1 identified by match to protein family HMM PF01345; match to protein family HMM TIGR01451 YP_002447049.1 identified by match to protein family HMM PF00106 YP_002447050.1 identified by match to protein family HMM PF00583 YP_002447051.1 catalyzes the formation of arginine and fumarate from arginosuccinate YP_002447052.1 identified by glimmer YP_002447053.1 identified by match to protein family HMM PF01156 YP_002447054.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002447055.1 identified by match to protein family HMM PF06196 YP_002447056.1 identified by match to protein family HMM PF00171 YP_002447057.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002447058.1 identified by glimmer YP_002447059.1 identified by match to protein family HMM PF00432; match to protein family HMM TIGR01787 YP_002447060.1 identified by match to protein family HMM PF02681 YP_002447061.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002447062.1 identified by match to protein family HMM PF06961 YP_002447063.1 identified by glimmer YP_002447065.1 identified by match to protein family HMM PF01883 YP_002447066.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002447067.1 identified by match to protein family HMM PF02391 YP_002447068.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002447069.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002447070.1 identified by match to protein family HMM PF01226 YP_002447071.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002447072.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002447074.1 identified by match to protein family HMM PF07849 YP_002447075.1 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_002447076.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002447077.1 identified by match to protein family HMM PF03323 YP_002447078.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002447079.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002447080.1 identified by glimmer YP_002447081.1 identified by glimmer YP_002447082.1 identified by glimmer YP_002447083.1 identified by match to protein family HMM PF00903 YP_002447086.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002447087.1 identified by match to protein family HMM PF00496 YP_002447088.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00496 YP_002447089.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447090.1 identified by match to protein family HMM PF00496 YP_002447091.1 involved in the transport of C4-dicarboxylates across the membrane YP_002447092.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002447093.1 identified by glimmer YP_002447094.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937 YP_002447096.1 identified by match to protein family HMM PF00005 YP_002447097.1 identified by match to protein family HMM PF00440 YP_002447098.1 identified by match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002447099.1 identified by match to protein family HMM PF06983 YP_002447100.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_002447101.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002447102.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002447103.1 identified by match to protein family HMM PF02629 YP_002447104.1 identified by match to protein family HMM PF00089 YP_002447105.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002447106.1 identified by match to protein family HMM TIGR02491 YP_002447107.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002447108.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002447109.1 identified by match to protein family HMM PF01521 YP_002447110.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_002447111.1 identified by match to protein family HMM PF00704; match to protein family HMM PF01476 YP_002447112.1 SASP N; found in forespore compartment YP_002447114.1 3'-5' exonuclease of DNA polymerase III YP_002447115.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002447116.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002447117.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002447118.1 Catalyzes the conversion of citrate to isocitrate YP_002447119.1 SASP O; found in forespore compartment YP_002447120.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02764 YP_002447122.1 SASP P; found in forespore compartment YP_002447124.1 identified by match to protein family HMM PF07690 YP_002447126.1 identified by match to protein family HMM PF02272; match to protein family HMM PF07973 YP_002447127.1 identified by match to protein family HMM PF00293 YP_002447128.1 identified by glimmer YP_002447129.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002447130.1 activates fatty acids by binding to coenzyme A YP_002447131.1 identified by match to protein family HMM PF02632 YP_002447132.1 identified by match to protein family HMM PF00501 YP_002447133.1 identified by match to protein family HMM PF01381 YP_002447135.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447136.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002447137.1 identified by match to protein family HMM PF05532 YP_002447139.1 identified by match to protein family HMM PF01510 YP_002447140.1 identified by glimmer YP_002447141.1 identified by match to protein family HMM PF02588 YP_002447142.1 identified by match to protein family HMM PF00903 YP_002447143.1 identified by glimmer YP_002447144.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002447145.1 identified by match to protein family HMM PF02230 YP_002447146.1 identified by match to protein family HMM PF00903 YP_002447147.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002447149.1 identified by match to protein family HMM PF01645 YP_002447150.1 identified by match to protein family HMM PF00724 YP_002447151.1 identified by match to protein family HMM PF02559 YP_002447152.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002447153.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002447154.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002447155.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002447156.1 regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure YP_002447157.1 identified by match to protein family HMM PF05401; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002447158.1 identified by match to protein family HMM PF01965 YP_002447160.1 identified by glimmer YP_002447162.1 identified by match to protein family HMM PF07301 YP_002447163.1 identified by match to protein family HMM PF02683 YP_002447164.1 identified by glimmer YP_002447165.1 identified by glimmer YP_002447166.1 identified by match to protein family HMM PF00892 YP_002447167.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002447169.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00005 YP_002447170.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002447172.1 identified by glimmer YP_002447173.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002447174.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002447175.1 identified by match to protein family HMM PF04172 YP_002447176.1 identified by match to protein family HMM PF00293 YP_002447177.1 identified by glimmer YP_002447178.1 identified by match to protein family HMM PF01925 YP_002447179.1 identified by glimmer YP_002447180.1 identified by glimmer YP_002447182.1 identified by match to protein family HMM PF01183; match to protein family HMM PF08239 YP_002447183.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002447184.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002447185.1 identified by match to protein family HMM PF03672 YP_002447187.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002447188.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_002447189.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_002447190.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_002447191.1 identified by match to protein family HMM TIGR01098 YP_002447192.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002447193.1 identified by match to protein family HMM PF05979 YP_002447194.1 identified by match to protein family HMM PF00239 YP_002447195.1 Represses a number of genes involved in the response to DNA damage YP_002447197.1 identified by match to protein family HMM PF08006 YP_002447198.1 identified by match to protein family HMM PF03551 YP_002447200.1 identified by match to protein family HMM PF01551 YP_002447203.1 identified by glimmer YP_002447204.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002447206.1 identified by match to protein family HMM PF09669; match to protein family HMM TIGR02681 YP_002447208.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_002447209.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_002447210.1 identified by match to protein family HMM PF00376 YP_002447211.1 identified by match to protein family HMM PF01053; match to protein family HMM PF06838 YP_002447212.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR03156 YP_002447213.1 identified by match to protein family HMM PF03458 YP_002447215.1 identified by match to protein family HMM PF00004; match to protein family HMM TIGR02881 YP_002447216.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002447219.1 identified by glimmer YP_002447220.1 identified by glimmer YP_002447221.1 Stimulates the elongation of poly(A) tails YP_002447222.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002447223.1 identified by glimmer YP_002447224.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002447225.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427 YP_002447226.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002447227.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002447228.1 identified by match to protein family HMM PF00465 YP_002447229.1 identified by match to protein family HMM PF04238 YP_002447232.1 identified by match to protein family HMM PF00324 YP_002447233.1 identified by match to protein family HMM PF00704 YP_002447235.1 identified by match to protein family HMM PF00149 YP_002447236.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_002447237.1 identified by match to protein family HMM PF00216 YP_002447238.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00583 YP_002447239.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002447240.1 identified by match to protein family HMM PF00403; match to protein family HMM TIGR00003 YP_002447241.1 identified by match to protein family HMM PF02583 YP_002447243.1 identified by match to protein family HMM PF00196 YP_002447244.1 identified by match to protein family HMM PF02390; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002447245.1 identified by match to protein family HMM PF00756 YP_002447246.1 identified by match to protein family HMM PF00005 YP_002447247.1 identified by match to protein family HMM PF01032 YP_002447248.1 identified by match to protein family HMM PF01032 YP_002447249.1 identified by match to protein family HMM PF01497 YP_002447250.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447251.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633 YP_002447252.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02805 YP_002447253.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002447254.1 identified by match to protein family HMM PF00730; match to protein family HMM PF07934 YP_002447255.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002447256.1 identified by match to protein family HMM PF02588 YP_002447257.1 identified by glimmer YP_002447258.1 identified by match to protein family HMM PF00300 YP_002447259.1 identified by match to protein family HMM PF00561 YP_002447260.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002447261.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002447263.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_002447264.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993 YP_002447267.1 identified by match to protein family HMM PF04172 YP_002447268.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002447269.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002447270.1 identified by glimmer YP_002447272.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002447273.1 identified by match to protein family HMM PF00388 YP_002447274.1 identified by match to protein family HMM PF00082; match to protein family HMM PF04151 YP_002447275.1 identified by match to protein family HMM PF01476; match to protein family HMM PF07486 YP_002447276.1 identified by match to protein family HMM PF01266 YP_002447277.1 identified by match to protein family HMM PF00884 YP_002447279.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002447280.1 This protein performs the mismatch recognition step during the DNA repair process YP_002447282.1 identified by match to protein family HMM PF07050 YP_002447283.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002447284.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_002447285.1 identified by match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02780 YP_002447286.1 identified by match to protein family HMM PF01244 YP_002447287.1 identified by match to protein family HMM PF04232 YP_002447288.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00282 YP_002447289.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_002447290.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002447291.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00177; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200 YP_002447292.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002447296.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002447297.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002447298.1 identified by match to protein family HMM PF05193 YP_002447299.1 identified by match to protein family HMM PF02653 YP_002447300.1 identified by match to protein family HMM PF02653 YP_002447301.1 identified by match to protein family HMM PF00005 YP_002447302.1 identified by match to protein family HMM PF02608 YP_002447303.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002447304.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397 YP_002447306.1 identified by match to protein family HMM PF00574 YP_002447307.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002447308.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002447309.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive YP_002447310.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002447313.1 identified by glimmer YP_002447316.1 identified by match to protein family HMM PF01183 YP_002447318.1 identified by glimmer YP_002447319.1 identified by match to protein family HMM TIGR01665 YP_002447320.1 identified by match to protein family HMM TIGR01633 YP_002447322.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002447325.1 identified by match to protein family HMM TIGR01603 YP_002447328.1 identified by match to protein family HMM TIGR01563 YP_002447331.1 identified by match to protein family HMM PF00574 YP_002447332.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002447333.1 identified by match to protein family HMM PF03354 YP_002447335.1 identified by match to protein family HMM PF01844 YP_002447336.1 identified by glimmer YP_002447339.1 identified by glimmer YP_002447340.1 identified by match to protein family HMM PF00313 YP_002447341.1 identified by match to protein family HMM PF00589 YP_002447342.1 identified by match to protein family HMM TIGR01637 YP_002447343.1 identified by glimmer YP_002447346.1 identified by glimmer YP_002447347.1 identified by glimmer YP_002447350.1 identified by glimmer YP_002447351.1 unwinds double stranded DNA YP_002447352.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002447353.1 identified by glimmer YP_002447355.1 identified by glimmer YP_002447357.1 identified by glimmer YP_002447359.1 identified by match to protein family HMM PF01381 YP_002447360.1 identified by match to protein family HMM PF01381 YP_002447361.1 identified by match to protein family HMM PF06114 YP_002447362.1 identified by glimmer YP_002447363.1 identified by glimmer YP_002447364.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002447365.1 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme YP_002447366.1 catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance YP_002447367.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888 YP_002447368.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002447369.1 identified by match to protein family HMM PF01522; match to protein family HMM TIGR02873 YP_002447370.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; match to protein family HMM TIGR03591 YP_002447371.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002447372.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002447373.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002447374.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002447375.1 identified by match to protein family HMM PF04456 YP_002447376.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002447377.1 identified by match to protein family HMM PF01248 YP_002447378.1 identified by match to protein family HMM PF04296 YP_002447379.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002447380.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002447381.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_002447382.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002447383.1 identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054 YP_002447384.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002447385.1 identified by match to protein family HMM PF01148 YP_002447386.1 identified by glimmer YP_002447387.1 catalyzes the formation of UDP-pyrophosphate from isopentenyl pyrophosphate YP_002447388.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002447389.1 Catalyzes the phosphorylation of UMP to UDP YP_002447390.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002447391.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002447392.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_002447393.1 heat shock protein involved in degradation of misfolded proteins YP_002447394.1 heat shock protein involved in degradation of misfolded proteins YP_002447395.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002447396.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_002447397.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002447398.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002447399.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002447400.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002447401.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002447402.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_002447403.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002447404.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002447405.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002447406.1 Essential for efficient processing of 16S rRNA YP_002447408.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002447409.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959 YP_002447410.1 identified by match to protein family HMM PF04297; match to protein family HMM PF08281 YP_002447411.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064 YP_002447412.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168 YP_002447413.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002447414.1 carries the fatty acid chain in fatty acid biosynthesis YP_002447415.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002447416.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002447417.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002447418.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_002447419.1 catalyzes branch migration in Holliday junction intermediates YP_002447420.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR03599 YP_002447421.1 identified by match to protein family HMM PF03780 YP_002447422.1 required for 70S ribosome assembly YP_002447423.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378 YP_002447424.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002447425.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002447426.1 identified by match to protein family HMM PF00069; match to protein family HMM PF03793; match to protein family HMM PF07714 YP_002447427.1 identified by match to protein family HMM PF00481; match to protein family HMM PF07228 YP_002447428.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002447429.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563 YP_002447430.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002447431.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002447432.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002447433.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002447434.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002447435.1 Essential for recycling GMP and indirectly, cGMP YP_002447436.1 identified by match to protein family HMM PF04025 YP_002447437.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_002447438.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002447439.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833 YP_002447440.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002447443.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002447444.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447447.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002447448.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002447449.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_002447450.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_002447451.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002447452.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002447453.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002447454.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002447455.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002447456.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_002447457.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005 YP_002447458.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002447460.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002447461.1 identified by match to protein family HMM PF05103; match to protein family HMM TIGR03544 YP_002447462.1 identified by match to protein family HMM PF01479 YP_002447463.1 identified by match to protein family HMM PF02325 YP_002447464.1 identified by match to protein family HMM PF04472 YP_002447465.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_002447466.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_002447467.1 identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888 YP_002447468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin YP_002447469.1 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation YP_002447470.1 identified by match to protein family HMM PF03419; match to protein family HMM TIGR02854 YP_002447471.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002447472.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174 YP_002447473.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478 YP_002447474.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002447475.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002447476.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615 YP_002447477.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002447478.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002447479.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002447480.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; match to protein family HMM TIGR02214 YP_002447481.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002447482.1 identified by match to protein family HMM PF04977; match to protein family HMM TIGR02209 YP_002447483.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002447485.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002447486.1 identified by match to protein family HMM PF00583 YP_002447487.1 identified by match to protein family HMM TIGR02894 YP_002447488.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002447489.1 identified by match to protein family HMM PF02620 YP_002447490.1 identified by match to protein family HMM PF05636 YP_002447491.1 identified by match to protein family HMM PF00665 YP_002447493.1 identified by match to protein family HMM PF05362 YP_002447494.1 identified by match to protein family HMM PF01734 YP_002447495.1 identified by match to protein family HMM PF07670; match to protein family HMM TIGR02871 YP_002447496.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002447497.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095 YP_002447500.1 identified by match to protein family HMM PF07050 YP_002447501.1 identified by match to protein family HMM PF00300 YP_002447504.1 identified by match to protein family HMM PF00188 YP_002447505.1 identified by match to protein family HMM PF08868 YP_002447506.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate YP_002447507.1 identified by match to protein family HMM PF09678; match to protein family HMM TIGR02737 YP_002447508.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02908 YP_002447509.1 identified by match to protein family HMM PF00510 YP_002447510.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02891 YP_002447511.1 identified by match to protein family HMM PF00034; match to protein family HMM PF00116; match to protein family HMM PF02790; match to protein family HMM TIGR02866 YP_002447512.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002447513.1 identified by match to protein family HMM PF02628 YP_002447514.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_002447515.1 identified by match to protein family HMM PF01098 YP_002447516.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein YP_002447518.1 identified by match to protein family HMM PF02562 YP_002447519.1 identified by match to protein family HMM PF01243 YP_002447521.1 identified by glimmer YP_002447523.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF08477; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002447524.1 identified by glimmer YP_002447525.1 identified by match to protein family HMM PF00459 YP_002447527.1 identified by match to protein family HMM PF06335 YP_002447528.1 identified by match to protein family HMM PF05256 YP_002447529.1 identified by match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002447530.1 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links YP_002447533.1 identified by glimmer YP_002447535.1 identified by glimmer YP_002447536.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002447537.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 YP_002447538.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002447539.1 identified by match to protein family HMM PF00676; match to protein family HMM TIGR03181 YP_002447540.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002447541.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002447542.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002447543.1 identified by match to protein family HMM PF07288 YP_002447544.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002447545.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254 YP_002447547.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002447548.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; match to protein family HMM TIGR03532 YP_002447549.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002447550.1 identified by match to protein family HMM PF00571 YP_002447552.1 identified by match to protein family HMM PF04308 YP_002447553.1 identified by glimmer YP_002447554.1 identified by match to protein family HMM PF08796 YP_002447555.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02196 YP_002447556.1 identified by glimmer YP_002447557.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002447558.1 identified by match to protein family HMM PF00563 YP_002447559.1 identified by match to protein family HMM PF00106 YP_002447560.1 identified by match to protein family HMM PF00149 YP_002447561.1 identified by glimmer YP_002447562.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02503 YP_002447563.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02503 YP_002447564.1 identified by match to protein family HMM PF02541 YP_002447568.1 identified by glimmer YP_002447569.1 identified by glimmer YP_002447570.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002447571.1 identified by match to protein family HMM PF03551 YP_002447572.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002447576.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002447577.1 identified by glimmer YP_002447578.1 identified by glimmer YP_002447579.1 identified by match to protein family HMM PF00155 YP_002447580.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002447581.1 identified by match to protein family HMM PF00528 YP_002447582.1 identified by match to protein family HMM PF00528 YP_002447583.1 identified by match to protein family HMM PF01547 YP_002447584.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903 YP_002447585.1 identified by match to protein family HMM PF00128 YP_002447586.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002447587.1 identified by match to protein family HMM PF00106 YP_002447588.1 identified by glimmer YP_002447589.1 identified by match to protein family HMM PF06271 YP_002447593.1 identified by match to protein family HMM PF02463 YP_002447594.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002447595.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00293 YP_002447596.1 identified by glimmer YP_002447597.1 identified by glimmer YP_002447601.1 identified by match to protein family HMM PF03551 YP_002447602.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_002447604.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_002447605.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002447606.1 identified by match to protein family HMM PF00795 YP_002447607.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however YP_002447608.1 converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage YP_002447609.1 converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage YP_002447610.1 converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage YP_002447611.1 identified by match to protein family HMM PF03079; match to protein family HMM PF07883 YP_002447612.1 identified by glimmer YP_002447613.1 identified by glimmer YP_002447614.1 identified by match to protein family HMM PF03446 YP_002447615.1 identified by match to protein family HMM PF00144 YP_002447616.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002447617.1 identified by match to protein family HMM PF00881 YP_002447618.1 identified by glimmer YP_002447619.1 identified by glimmer YP_002447620.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002447621.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002447622.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02002 YP_002447623.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002447624.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002447625.1 identified by match to protein family HMM PF07702 YP_002447626.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002447627.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR00221 YP_002447628.1 identified by match to protein family HMM PF00753 YP_002447629.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer YP_002447630.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_002447631.1 identified by match to protein family HMM PF03745 YP_002447632.1 identified by match to protein family HMM PF00583 YP_002447633.1 identified by match to protein family HMM PF00160 YP_002447634.1 identified by match to protein family HMM PF06207 YP_002447635.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002447636.1 identified by match to protein family HMM PF03323 YP_002447638.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839 YP_002447639.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845 YP_002447640.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838 YP_002447643.1 identified by glimmer YP_002447644.1 identified by match to protein family HMM PF00209 YP_002447645.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. YP_002447646.1 binds to sigma F preventing its association with RNA polymerase during sporulation YP_002447647.1 identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; match to protein family HMM TIGR02886 YP_002447648.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002447649.1 identified by match to protein family HMM PF00392; match to protein family HMM PF02082 YP_002447650.1 identified by match to protein family HMM PF00005 YP_002447654.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447655.1 identified by match to protein family HMM PF01047 YP_002447656.1 identified by match to protein family HMM PF04402 YP_002447657.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002447658.1 identified by match to protein family HMM PF01544; match to protein family HMM TIGR00383 YP_002447659.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002447660.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002447661.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002447663.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002447665.1 identified by match to protein family HMM PF01475 YP_002447666.1 identified by match to protein family HMM PF01944; match to protein family HMM TIGR02831 YP_002447667.1 identified by match to protein family HMM PF00583 YP_002447668.1 identified by match to protein family HMM PF00293 YP_002447670.1 identified by match to protein family HMM PF00248 YP_002447671.1 identified by match to protein family HMM PF00248 YP_002447672.1 identified by match to protein family HMM PF04229 YP_002447674.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002447675.1 identified by match to protein family HMM PF01402 YP_002447676.1 identified by match to protein family HMM PF00561 YP_002447677.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002447678.1 identified by match to protein family HMM PF00356 YP_002447679.1 identified by match to protein family HMM PF00583 YP_002447682.1 identified by match to protein family HMM PF09360 YP_002447683.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_002447684.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002447685.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_002447686.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002447688.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_002447689.1 identified by match to protein family HMM PF05401; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR02072 YP_002447690.1 identified by match to protein family HMM PF00561 YP_002447691.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002447692.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002447693.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002447694.1 identified by glimmer YP_002447695.1 identified by glimmer YP_002447696.1 identified by match to protein family HMM PF03553; match to protein family HMM PF03600; match to protein family HMM TIGR00931 YP_002447697.1 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002447698.1 identified by match to protein family HMM PF00657 YP_002447699.1 identified by match to protein family HMM PF01047 YP_002447701.1 identified by glimmer YP_002447702.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_002447703.1 identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707 YP_002447704.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002447705.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_002447706.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002447707.1 identified by glimmer YP_002447708.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002447709.1 identified by match to protein family HMM PF00753 YP_002447710.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002447711.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_002447712.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_002447713.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447714.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447715.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002447716.1 identified by glimmer YP_002447718.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524 YP_002447719.1 identified by match to protein family HMM PF02308 YP_002447720.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002447721.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01883 YP_002447722.1 identified by match to protein family HMM PF00583 YP_002447723.1 identified by glimmer YP_002447724.1 identified by match to protein family HMM PF03734 YP_002447725.1 identified by match to protein family HMM PF06081 YP_002447726.1 identified by match to protein family HMM PF00005 YP_002447727.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002447728.1 identified by match to protein family HMM PF00497; match to protein family HMM PF04069 YP_002447729.1 identified by glimmer YP_002447730.1 identified by match to protein family HMM PF06491 YP_002447732.1 identified by match to protein family HMM PF00293 YP_002447733.1 identified by match to protein family HMM PF04239 YP_002447734.1 identified by match to protein family HMM PF01098 YP_002447735.1 identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817 YP_002447736.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002447737.1 identified by match to protein family HMM PF00676 YP_002447738.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002447739.1 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate YP_002447740.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002447741.1 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate YP_002447742.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00989; match to protein family HMM PF02954; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002447744.1 identified by match to protein family HMM PF03009 YP_002447747.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08769; match to protein family HMM TIGR02875 YP_002447748.1 identified by match to protein family HMM PF00595; match to protein family HMM PF05580; match to protein family HMM TIGR02860 YP_002447749.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002447750.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002447751.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478 YP_002447752.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002447753.1 identified by match to protein family HMM PF00348 YP_002447754.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002447755.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002447756.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002447757.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002447758.1 identified by match to protein family HMM PF03780 YP_002447759.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002447760.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002447762.1 identified by match to protein family HMM TIGR02830 YP_002447763.1 identified by match to protein family HMM PF09581; match to protein family HMM TIGR02896 YP_002447764.1 identified by match to protein family HMM PF09546; match to protein family HMM TIGR02829 YP_002447765.1 identified by match to protein family HMM PF09555; match to protein family HMM TIGR02849 YP_002447766.1 identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848 YP_002447767.1 necessary for complete engulfment of forespore YP_002447768.1 identified by match to protein family HMM TIGR02858 YP_002447772.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002447773.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002447774.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002447776.1 identified by match to protein family HMM PF07136 YP_002447778.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002447779.1 involved in manganese homeostasis; activates the transcription of the mntABCD operon YP_002447780.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00620 YP_002447781.1 identified by match to protein family HMM PF03551 YP_002447784.1 identified by glimmer YP_002447785.1 identified by match to protein family HMM PF03099 YP_002447786.1 identified by match to protein family HMM PF00581 YP_002447788.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002447789.1 identified by match to protein family HMM PF00440 YP_002447790.1 identified by match to protein family HMM PF00893 YP_002447791.1 identified by match to protein family HMM PF00893 YP_002447792.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002447793.1 identified by glimmer YP_002447796.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_002447797.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_002447798.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002447799.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002447802.1 identified by glimmer YP_002447806.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002447807.1 identified by match to protein family HMM PF03171 YP_002447808.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447809.1 identified by glimmer YP_002447810.1 identified by glimmer YP_002447812.1 identified by glimmer YP_002447814.1 identified by glimmer YP_002447815.1 identified by glimmer YP_002447816.1 identified by glimmer YP_002447817.1 identified by match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002447818.1 identified by match to protein family HMM PF01797 YP_002447823.1 identified by match to protein family HMM PF00375 YP_002447825.1 identified by glimmer YP_002447827.1 identified by glimmer YP_002447828.1 identified by glimmer YP_002447830.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002447831.1 identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607; match to protein family HMM PF02965; match to protein family HMM TIGR02082 YP_002447832.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_002447833.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity YP_002447834.1 catalyzes the formation of L-homocysteine from cystathionine YP_002447835.1 identified by match to protein family HMM PF00857 YP_002447836.1 identified by match to protein family HMM PF01022 YP_002447837.1 identified by match to protein family HMM PF02636 YP_002447838.1 identified by match to protein family HMM PF00753 YP_002447839.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002447840.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744 YP_002447841.1 identified by match to protein family HMM PF06014 YP_002447842.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727 YP_002447843.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002447844.1 identified by match to protein family HMM PF00132; match to protein family HMM PF00483; match to protein family HMM PF02878 YP_002447845.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002447846.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002447847.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002447848.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002447849.1 identified by match to protein family HMM TIGR02136 YP_002447850.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002447851.1 identified by match to protein family HMM PF07690 YP_002447852.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002447853.1 identified by glimmer YP_002447854.1 identified by match to protein family HMM PF06691 YP_002447856.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002447857.1 identified by match to protein family HMM PF01475 YP_002447858.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032 YP_002447859.1 identified by match to protein family HMM PF00005 YP_002447860.1 identified by match to protein family HMM PF02588 YP_002447862.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002447863.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002447865.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002447866.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002447867.1 identified by match to protein family HMM PF04816 YP_002447868.1 identified by match to protein family HMM PF00034 YP_002447869.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_002447870.1 synthesizes RNA primers at the replication forks YP_002447871.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447872.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002447873.1 identified by match to protein family HMM PF03618 YP_002447874.1 identified by match to protein family HMM PF00571; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002447875.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002447877.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002447878.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002447879.1 identified by match to protein family HMM PF01219 YP_002447880.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002447881.1 identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277 YP_002447882.1 identified by match to protein family HMM PF02562 YP_002447883.1 identified by match to protein family HMM PF06898; match to protein family HMM TIGR02876 YP_002447884.1 identified by match to protein family HMM PF07241; match to protein family HMM TIGR02856 YP_002447885.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447886.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447887.1 identified by match to protein family HMM PF09424 YP_002447888.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002447889.1 identified by match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579 YP_002447890.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002447891.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002447892.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002447893.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002447894.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002447895.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_002447896.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002447897.1 identified by match to protein family HMM PF01638 YP_002447898.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002447900.1 Initiates the rapid degradation of small, acid-soluble proteins during spore germination YP_002447901.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002447902.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002447904.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002447905.1 identified by match to protein family HMM PF00383; match to protein family HMM TIGR02571 YP_002447906.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426 YP_002447907.1 may be involved in regulation of competence genes YP_002447908.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002447909.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002447910.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488 YP_002447911.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002447912.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253 YP_002447913.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002447914.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_002447915.1 identified by match to protein family HMM PF09419; match to protein family HMM TIGR01662; match to protein family HMM TIGR01668 YP_002447916.1 identified by match to protein family HMM PF08970 YP_002447917.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002447918.1 sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment YP_002447920.1 identified by match to protein family HMM PF03413 YP_002447921.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002447922.1 identified by match to protein family HMM PF00881 YP_002447923.1 identified by match to protein family HMM PF04607 YP_002447925.1 identified by match to protein family HMM PF00245 YP_002447926.1 identified by match to protein family HMM PF00583 YP_002447927.1 identified by match to protein family HMM PF00561 YP_002447928.1 identified by match to protein family HMM PF07681 YP_002447929.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447930.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002447931.1 identified by match to protein family HMM PF00300 YP_002447932.1 identified by glimmer YP_002447933.1 identified by glimmer YP_002447935.1 identified by match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF05922 YP_002447937.1 phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_002447938.1 identified by match to protein family HMM PF01329 YP_002447939.1 identified by match to protein family HMM PF00903 YP_002447940.1 identified by match to protein family HMM PF07681 YP_002447941.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002447942.1 identified by match to protein family HMM PF01575 YP_002447943.1 identified by match to protein family HMM PF00583 YP_002447944.1 identified by match to protein family HMM PF00583 YP_002447946.1 identified by match to protein family HMM PF00005 YP_002447947.1 identified by match to protein family HMM PF01032 YP_002447948.1 identified by match to protein family HMM PF01497 YP_002447950.1 identified by match to protein family HMM PF00465 YP_002447951.1 catalyzes the formation of L-homocysteine from cystathionine YP_002447952.1 identified by match to protein family HMM PF00291 YP_002447953.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002447954.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002447957.1 identified by match to protein family HMM PF00905 YP_002447959.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002447960.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002447961.1 identified by match to protein family HMM PF01136 YP_002447962.1 identified by match to protein family HMM PF01136 YP_002447963.1 identified by match to protein family HMM PF01596 YP_002447964.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002447965.1 identified by match to protein family HMM PF06949 YP_002447966.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002447967.1 identified by match to protein family HMM PF06135 YP_002447968.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002447970.1 identified by match to protein family HMM PF01594 YP_002447971.1 identified by glimmer YP_002447972.1 identified by glimmer YP_002447974.1 identified by match to protein family HMM TIGR01448 YP_002447975.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002447976.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002447977.1 identified by match to protein family HMM PF00266 YP_002447978.1 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738 YP_002447979.1 identified by match to protein family HMM PF00004 YP_002447980.1 identified by match to protein family HMM TIGR02894 YP_002447981.1 identified by match to protein family HMM PF00899 YP_002447982.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002447983.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002447986.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002447987.1 identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002447988.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002447989.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002447990.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002447991.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002447993.1 identified by match to protein family HMM PF01554; match to protein family HMM PF01943; match to protein family HMM PF03023; match to protein family HMM TIGR02900 YP_002447994.1 identified by match to protein family HMM PF04239 YP_002447996.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002447997.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002447998.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002448000.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002448001.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002448002.1 identified by match to protein family HMM PF01497 YP_002448003.1 identified by match to protein family HMM PF08955; match to protein family HMM PF08977 YP_002448004.1 identified by glimmer YP_002448005.1 identified by match to protein family HMM PF09580 YP_002448006.1 identified by match to protein family HMM PF01476; match to protein family HMM TIGR02899 YP_002448007.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002448008.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002448009.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002448010.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002448011.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279 YP_002448012.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002448014.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002448015.1 identified by match to protein family HMM PF02687 YP_002448016.1 identified by match to protein family HMM PF02687 YP_002448017.1 identified by match to protein family HMM PF00005 YP_002448018.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002448019.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448020.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002448022.1 involved in the peptidyltransferase reaction during translation YP_002448023.1 identified by match to protein family HMM PF04327 YP_002448024.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002448025.1 identified by match to protein family HMM TIGR00757 YP_002448026.1 identified by match to protein family HMM PF02163 YP_002448027.1 identified by match to protein family HMM PF01551 YP_002448028.1 identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968 YP_002448029.1 blocks the formation of polar Z-ring septums YP_002448030.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426 YP_002448031.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002448032.1 functions in MreBCD complex in some organisms YP_002448033.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002448034.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002448036.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002448037.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002448038.1 identified by match to protein family HMM TIGR02904 YP_002448039.1 identified by match to protein family HMM PF01476; match to protein family HMM TIGR02907 YP_002448040.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002448041.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002448042.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002448043.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002448044.1 identified by match to protein family HMM PF01578 YP_002448045.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002448046.1 identified by match to protein family HMM PF01047 YP_002448047.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03561 YP_002448048.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002448049.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_002448050.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01078; match to protein family HMM PF05362; match to protein family HMM TIGR02902 YP_002448051.1 binds and unfolds substrates as part of the ClpXP protease YP_002448052.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002448054.1 identified by glimmer YP_002448056.1 identified by glimmer YP_002448057.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002448058.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_002448059.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002448061.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002448062.1 identified by glimmer YP_002448063.1 identified by match to protein family HMM PF07690 YP_002448064.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01965 YP_002448065.1 identified by match to protein family HMM PF00440 YP_002448066.1 identified by match to protein family HMM PF01965 YP_002448067.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002448068.1 identified by match to protein family HMM PF00860 YP_002448069.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_002448070.1 identified by match to protein family HMM PF04024 YP_002448071.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002448073.1 identified by match to protein family HMM PF00230 YP_002448074.1 identified by match to protein family HMM PF02082 YP_002448076.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00005 YP_002448077.1 identified by match to protein family HMM PF03767; match to protein family HMM TIGR01533 YP_002448078.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002448079.1 With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_002448080.1 identified by match to protein family HMM PF02557 YP_002448081.1 identified by match to protein family HMM PF03061 YP_002448082.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002448083.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002448084.1 identified by match to protein family HMM TIGR02046 YP_002448086.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002448087.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002448088.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012 YP_002448089.1 identified by match to protein family HMM PF01012 YP_002448090.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002448091.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08359 YP_002448092.1 activates fatty acids by binding to coenzyme A YP_002448093.1 identified by match to protein family HMM PF01391 YP_002448094.1 identified by match to protein family HMM PF01497 YP_002448095.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002448097.1 identified by match to protein family HMM PF05163 YP_002448100.1 identified by glimmer YP_002448101.1 identified by match to protein family HMM PF00005 YP_002448102.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002448103.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448104.1 identified by glimmer YP_002448107.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_002448108.1 identified by match to protein family HMM PF07170; match to protein family HMM TIGR03064 YP_002448109.1 identified by match to protein family HMM PF00005 YP_002448110.1 identified by match to protein family HMM PF01032 YP_002448111.1 identified by match to protein family HMM PF01497 YP_002448112.1 identified by match to protein family HMM PF05031; match to protein family HMM TIGR03063 YP_002448113.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05031 YP_002448114.1 identified by match to protein family HMM PF05031; match to protein family HMM TIGR03063 YP_002448115.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002448116.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002448117.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_002448118.1 identified by match to protein family HMM PF02811 YP_002448119.1 identified by match to protein family HMM PF02674 YP_002448120.1 identified by match to protein family HMM PF05164 YP_002448121.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002448123.1 identified by glimmer YP_002448124.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002448125.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002448126.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002448127.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002448128.1 identified by match to protein family HMM TIGR03092 YP_002448129.1 identified by match to protein family HMM PF01966 YP_002448130.1 identified by match to protein family HMM PF02517 YP_002448131.1 identified by glimmer YP_002448132.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002448134.1 identified by match to protein family HMM PF00440 YP_002448135.1 identified by match to protein family HMM PF05343 YP_002448136.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08761 YP_002448137.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002448138.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002448139.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002448140.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002448141.1 identified by match to protein family HMM PF08812; match to protein family HMM TIGR02834 YP_002448142.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_002448143.1 identified by match to protein family HMM PF07261 YP_002448144.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002448145.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002448146.1 identified by glimmer YP_002448147.1 NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis YP_002448148.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002448149.1 identified by match to protein family HMM PF02659; match to protein family HMM TIGR02840 YP_002448150.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002448151.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002448152.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002448153.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448154.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002448155.1 identified by match to protein family HMM PF01575 YP_002448156.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_002448157.1 Converts isocitrate to alpha ketoglutarate YP_002448158.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_002448159.1 identified by match to protein family HMM PF04284 YP_002448160.1 identified by glimmer YP_002448161.1 identified by match to protein family HMM PF01594; match to protein family HMM TIGR02872 YP_002448162.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_002448163.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002448164.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002448165.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002448166.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002448167.1 identified by match to protein family HMM PF00392 YP_002448168.1 identified by match to protein family HMM PF00390; match to protein family HMM PF03949 YP_002448169.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_002448172.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002448175.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085 YP_002448176.1 identified by glimmer YP_002448177.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_002448178.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002448183.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448185.1 identified by match to protein family HMM PF00583 YP_002448186.1 identified by match to protein family HMM PF07883 YP_002448187.1 identified by glimmer YP_002448188.1 identified by match to protein family HMM PF01262; match to protein family HMM PF01488; match to protein family HMM PF05222; match to protein family HMM TIGR00518 YP_002448189.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002448190.1 identified by match to protein family HMM PF00582 YP_002448191.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448194.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002448195.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_002448198.1 identified by glimmer YP_002448199.1 identified by match to protein family HMM PF02588 YP_002448201.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer YP_002448202.1 identified by match to protein family HMM PF00293 YP_002448203.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002448204.1 identified by match to protein family HMM PF02384 YP_002448205.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002448206.1 identified by match to protein family HMM PF09579; match to protein family HMM TIGR02874 YP_002448208.1 catalyzes the phosphorylation of NAD to NADP YP_002448209.1 identified by match to protein family HMM PF07969 YP_002448210.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002448211.1 identified by match to protein family HMM PF00501 YP_002448212.1 identified by match to protein family HMM PF00269 YP_002448213.1 Required for the synthesis of the thiazole moiety YP_002448214.1 identified by match to protein family HMM PF00266 YP_002448215.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_002448216.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002448217.1 identified by match to protein family HMM PF00892 YP_002448218.1 identified by match to protein family HMM PF00440 YP_002448220.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_002448221.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002448225.1 identified by glimmer YP_002448226.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002448227.1 identified by match to protein family HMM PF00132 YP_002448228.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002448230.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01842 YP_002448231.1 identified by match to protein family HMM PF00850 YP_002448232.1 identified by match to protein family HMM PF00561 YP_002448233.1 identified by glimmer YP_002448234.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448235.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002448236.1 identified by match to protein family HMM PF00023 YP_002448237.1 identified by match to protein family HMM PF01408 YP_002448238.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002448240.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448241.1 identified by glimmer YP_002448243.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481 YP_002448244.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts YP_002448245.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448246.1 identified by match to protein family HMM PF07537 YP_002448248.1 identified by match to protein family HMM PF06103 YP_002448249.1 identified by match to protein family HMM PF02073 YP_002448251.1 identified by match to protein family HMM PF00583 YP_002448252.1 identified by match to protein family HMM PF00583 YP_002448253.1 identified by match to protein family HMM PF00892 YP_002448254.1 identified by match to protein family HMM PF00376 YP_002448255.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002448256.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002448257.1 identified by match to protein family HMM PF01580; match to protein family HMM PF09397 YP_002448258.1 identified by match to protein family HMM PF01520 YP_002448259.1 identified by glimmer YP_002448260.1 identified by match to protein family HMM PF01588 YP_002448261.1 identified by match to protein family HMM PF07285 YP_002448262.1 identified by match to protein family HMM PF00085 YP_002448263.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002448264.1 identified by match to protein family HMM PF05343 YP_002448265.1 identified by match to protein family HMM PF03413 YP_002448266.1 identified by match to protein family HMM PF00753 YP_002448267.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002448269.1 identified by match to protein family HMM PF01636 YP_002448270.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104 YP_002448271.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_002448272.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_002448273.1 identified by match to protein family HMM PF08220 YP_002448274.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002448275.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002448276.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_002448277.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002448278.1 identified by match to protein family HMM PF01022 YP_002448279.1 identified by match to protein family HMM PF08327 YP_002448280.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer YP_002448283.1 identified by match to protein family HMM PF02559 YP_002448284.1 Converts glucose to D-glucono-1,5 lactone YP_002448285.1 identified by match to protein family HMM PF06800; match to protein family HMM TIGR00776 YP_002448286.1 identified by glimmer YP_002448287.1 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682 YP_002448288.1 identified by match to protein family HMM PF02391 YP_002448289.1 identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176 YP_002448290.1 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177 YP_002448291.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002448292.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_002448293.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06463; match to protein family HMM TIGR02666 YP_002448294.1 identified by match to protein family HMM PF01391 YP_002448295.1 identified by glimmer YP_002448297.1 identified by match to protein family HMM PF00581 YP_002448298.1 identified by glimmer YP_002448299.1 catalyzes the formation of O-acetyl -L-homoserine from L-homoserine and acetyl-CoA YP_002448300.1 identified by match to protein family HMM PF03323 YP_002448301.1 identified by match to protein family HMM PF03845; match to protein family HMM TIGR00912 YP_002448302.1 identified by match to protein family HMM PF05504; match to protein family HMM TIGR02887 YP_002448305.1 identified by match to protein family HMM PF01391 YP_002448306.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002448307.1 identified by match to protein family HMM PF07690 YP_002448308.1 identified by match to protein family HMM PF00999 YP_002448309.1 identified by match to protein family HMM PF02080 YP_002448310.1 identified by match to protein family HMM PF00589 YP_002448311.1 identified by match to protein family HMM PF02687 YP_002448312.1 identified by match to protein family HMM PF00005 YP_002448313.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002448314.1 identified by glimmer YP_002448316.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_002448317.1 identified by match to protein family HMM PF06962 YP_002448318.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002448319.1 identified by match to protein family HMM PF03929 YP_002448321.1 identified by match to protein family HMM PF00561 YP_002448322.1 identified by match to protein family HMM PF00132 YP_002448323.1 identified by match to protein family HMM PF01569 YP_002448324.1 identified by match to protein family HMM PF00534 YP_002448326.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177 YP_002448327.1 identified by glimmer YP_002448329.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002448330.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002448331.1 identified by glimmer YP_002448332.1 identified by match to protein family HMM PF05468 YP_002448333.1 identified by glimmer YP_002448334.1 identified by glimmer YP_002448335.1 identified by match to protein family HMM PF00892 YP_002448337.1 identified by match to protein family HMM PF01784 YP_002448338.1 identified by glimmer YP_002448339.1 identified by match to protein family HMM PF06030 YP_002448344.1 identified by match to protein family HMM PF02518 YP_002448345.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002448346.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448347.1 identified by match to protein family HMM PF00199; match to protein family HMM PF06628 YP_002448348.1 identified by match to protein family HMM PF00561 YP_002448349.1 identified by match to protein family HMM PF00884 YP_002448351.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448352.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448353.1 identified by glimmer YP_002448354.1 identified by match to protein family HMM PF09084 YP_002448355.1 identified by match to protein family HMM PF00005 YP_002448356.1 identified by match to protein family HMM PF00528 YP_002448357.1 identified by glimmer YP_002448358.1 identified by glimmer YP_002448359.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002448361.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR02705 YP_002448363.1 identified by glimmer YP_002448366.1 identified by match to protein family HMM PF00893 YP_002448367.1 identified by match to protein family HMM PF00893 YP_002448368.1 identified by match to protein family HMM PF00376 YP_002448369.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002448370.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_002448371.1 identified by match to protein family HMM PF00484 YP_002448372.1 identified by match to protein family HMM PF01654 YP_002448373.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002448375.1 identified by match to protein family HMM PF02698 YP_002448377.1 identified by match to protein family HMM PF02588 YP_002448379.1 identified by glimmer YP_002448381.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF04012 YP_002448384.1 identified by match to protein family HMM PF01926; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00437 YP_002448385.1 identified by match to protein family HMM PF04023 YP_002448386.1 identified by match to protein family HMM PF09515; match to protein family HMM TIGR02357 YP_002448387.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002448388.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448389.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002448390.1 identified by match to protein family HMM TIGR01167 YP_002448391.1 identified by glimmer YP_002448392.1 identified by glimmer YP_002448393.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002448394.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_002448396.1 identified by match to protein family HMM TIGR01784 YP_002448398.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448401.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448402.1 identified by match to protein family HMM PF02687 YP_002448403.1 identified by glimmer YP_002448404.1 identified by match to protein family HMM PF04085; match to protein family HMM TIGR00219 YP_002448405.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002448406.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002448407.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448408.1 identified by match to protein family HMM PF09335 YP_002448410.1 identified by match to protein family HMM PF02687 YP_002448411.1 identified by match to protein family HMM PF00005 YP_002448412.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002448414.1 identified by match to protein family HMM PF00005 YP_002448415.1 identified by match to protein family HMM PF07853 YP_002448416.1 identified by match to protein family HMM PF01022 YP_002448418.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448419.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002448420.1 identified by match to protein family HMM PF02687 YP_002448421.1 identified by match to protein family HMM PF02687 YP_002448422.1 identified by match to protein family HMM PF00005 YP_002448423.1 identified by match to protein family HMM PF02687 YP_002448424.1 identified by match to protein family HMM PF09680; match to protein family HMM TIGR01732 YP_002448425.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002448426.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002448427.1 identified by match to protein family HMM PF00294 YP_002448428.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002448429.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002448430.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002448431.1 identified by match to protein family HMM PF02557 YP_002448432.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002448433.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448434.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; match to protein family HMM TIGR01928 YP_002448435.1 converts O-succinylbenzoate to O-succinylbenzoyl-CoA YP_002448436.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002448437.1 identified by match to protein family HMM PF00561 YP_002448438.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002448439.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002448440.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002448441.1 identified by match to protein family HMM TIGR02890 YP_002448442.1 identified by match to protein family HMM PF00313 YP_002448443.1 identified by match to protein family HMM PF01987; match to protein family HMM TIGR00266 YP_002448445.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739 YP_002448446.1 identified by match to protein family HMM PF01764 YP_002448447.1 identified by glimmer YP_002448448.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002448449.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002448450.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR02092 YP_002448451.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002448452.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002448454.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002448455.1 identified by match to protein family HMM PF00440 YP_002448456.1 identified by match to protein family HMM PF07690 YP_002448457.1 identified by match to protein family HMM PF02308 YP_002448458.1 identified by match to protein family HMM PF02254; match to protein family HMM PF07885 YP_002448459.1 identified by match to protein family HMM PF08868 YP_002448460.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002448461.1 identified by match to protein family HMM PF04070 YP_002448462.1 induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation YP_002448463.1 identified by match to protein family HMM PF00155 YP_002448464.1 identified by match to protein family HMM PF01037 YP_002448465.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002448466.1 identified by match to protein family HMM PF00561 YP_002448467.1 identified by match to protein family HMM PF08958 YP_002448468.1 identified by match to protein family HMM PF00155 YP_002448469.1 identified by match to protein family HMM PF00080 YP_002448471.1 identified by match to protein family HMM PF08810 YP_002448472.1 inhibitor of the KinA pathway of sporulation YP_002448473.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002448475.1 identified by match to protein family HMM PF08713 YP_002448476.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002448477.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002448479.1 identified by match to protein family HMM PF02632 YP_002448480.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_002448481.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002448482.1 identified by match to protein family HMM PF02457 YP_002448483.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002448484.1 identified by match to protein family HMM PF06725 YP_002448486.1 identified by match to protein family HMM PF00293 YP_002448487.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002448488.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002448489.1 identified by match to protein family HMM PF06445 YP_002448490.1 identified by match to protein family HMM PF07690 YP_002448492.1 identified by match to protein family HMM PF04463 YP_002448493.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002448494.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448496.1 identified by match to protein family HMM PF00583 YP_002448497.1 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049 YP_002448498.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002448499.1 identified by match to protein family HMM PF07293 YP_002448500.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002448501.1 identified by match to protein family HMM PF09388 YP_002448502.1 identified by match to protein family HMM PF00005 YP_002448503.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_002448504.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002448505.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448506.1 identified by glimmer YP_002448507.1 identified by glimmer YP_002448508.1 identified by match to protein family HMM PF09346 YP_002448509.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448510.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448512.1 identified by glimmer YP_002448514.1 identified by match to protein family HMM PF01909 YP_002448515.1 identified by match to protein family HMM PF07315 YP_002448516.1 identified by match to protein family HMM PF01106 YP_002448517.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts; identified by glimmer YP_002448518.1 identified by match to protein family HMM TIGR02905 YP_002448519.1 identified by match to protein family HMM PF04608 YP_002448520.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448522.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448524.1 identified by match to protein family HMM PF08282 YP_002448525.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002448527.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460 YP_002448528.1 identified by match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002448529.1 identified by match to protein family HMM PF01934 YP_002448530.1 similar to GlpX type II fructose-1,6-bisphosphatase YP_002448533.1 identified by match to protein family HMM PF06265 YP_002448534.1 identified by match to protein family HMM PF09580 YP_002448535.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739; match to protein family HMM PF09278 YP_002448537.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002448538.1 identified by match to protein family HMM PF00300 YP_002448539.1 identified by match to protein family HMM PF04073 YP_002448540.1 catalyzes the radical-mediated insertion of two sulfur atoms into an ACP (ACP) bound to an octanoyl group to produce a lipoyl group YP_002448541.1 identified by match to protein family HMM PF01551 YP_002448542.1 identified by match to protein family HMM PF09560; match to protein family HMM TIGR02832 YP_002448543.1 identified by match to protein family HMM PF08827 YP_002448545.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980 YP_002448546.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994 YP_002448547.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979 YP_002448548.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981 YP_002448549.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978 YP_002448550.1 identified by match to protein family HMM PF03180 YP_002448551.1 identified by match to protein family HMM PF03180 YP_002448552.1 identified by match to protein family HMM PF00528 YP_002448553.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002448554.1 identified by glimmer YP_002448556.1 identified by match to protein family HMM PF01751 YP_002448557.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448558.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002448559.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002448563.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002448564.1 identified by match to protein family HMM PF07875 YP_002448566.1 identified by match to protein family HMM PF00753 YP_002448567.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002448568.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002448569.1 identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737 YP_002448570.1 identified by glimmer YP_002448571.1 identified by match to protein family HMM PF00768; match to protein family HMM PF00905 YP_002448572.1 identified by match to protein family HMM PF01619 YP_002448574.1 identified by match to protein family HMM PF01910; match to protein family HMM TIGR00106 YP_002448575.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02743 YP_002448576.1 identified by match to protein family HMM PF01978 YP_002448578.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002448579.1 identified by match to protein family HMM PF00324 YP_002448581.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_002448582.1 identified by glimmer YP_002448583.1 identified by match to protein family HMM PF02588 YP_002448584.1 identified by match to protein family HMM PF00583 YP_002448585.1 identified by glimmer YP_002448587.1 identified by glimmer YP_002448588.1 identified by match to protein family HMM PF01381 YP_002448589.1 identified by match to protein family HMM PF09335 YP_002448590.1 identified by glimmer YP_002448591.1 identified by match to protein family HMM PF03734 YP_002448592.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448593.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002448594.1 identified by match to protein family HMM PF00892 YP_002448596.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002448597.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002448598.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002448599.1 identified by glimmer YP_002448600.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002448601.1 identified by match to protein family HMM PF01883 YP_002448602.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002448603.1 identified by match to protein family HMM PF02678 YP_002448604.1 identified by match to protein family HMM PF01047 YP_002448605.1 identified by glimmer YP_002448606.1 identified by match to protein family HMM PF09335 YP_002448607.1 identified by match to protein family HMM PF00999 YP_002448608.1 identified by match to protein family HMM PF02080 YP_002448609.1 identified by glimmer YP_002448610.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002448611.1 identified by match to protein family HMM PF00210 YP_002448613.1 identified by glimmer YP_002448615.1 identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730 YP_002448616.1 identified by match to protein family HMM PF03819 YP_002448617.1 identified by match to protein family HMM PF00210 YP_002448618.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002448619.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670 YP_002448620.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002448621.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002448622.1 identified by match to protein family HMM PF01370 YP_002448625.1 identified by match to protein family HMM PF00248 YP_002448626.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002448627.1 identified by match to protein family HMM PF01638 YP_002448629.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002448630.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002448631.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002448633.1 identified by match to protein family HMM PF00015 YP_002448634.1 identified by match to protein family HMM PF03372 YP_002448635.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002448636.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002448637.1 identified by glimmer YP_002448639.1 identified by match to protein family HMM PF07690 YP_002448640.1 identified by match to protein family HMM PF00005; match to protein family HMM PF02463 YP_002448641.1 identified by match to protein family HMM PF00583 YP_002448642.1 identified by glimmer YP_002448643.1 identified by match to protein family HMM PF06146 YP_002448644.1 identified by match to protein family HMM PF08378 YP_002448645.1 identified by match to protein family HMM PF00857 YP_002448646.1 identified by match to protein family HMM PF01037 YP_002448648.1 identified by match to protein family HMM PF01037 YP_002448649.1 identified by match to protein family HMM PF00484 YP_002448650.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_002448651.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594 YP_002448652.1 identified by match to protein family HMM PF01289 YP_002448653.1 identified by match to protein family HMM PF00005 YP_002448654.1 identified by match to protein family HMM PF01032 YP_002448655.1 identified by match to protein family HMM PF01032 YP_002448656.1 identified by match to protein family HMM PF01497 YP_002448657.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448658.1 identified by match to protein family HMM PF04167 YP_002448659.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002448660.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448661.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063 YP_002448663.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002448664.1 identified by match to protein family HMM PF04172 YP_002448665.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_002448666.1 identified by match to protein family HMM PF01156 YP_002448667.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002448668.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002448669.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002448670.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002448671.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002448672.1 identified by match to protein family HMM PF04198 YP_002448673.1 identified by match to protein family HMM PF00462; match to protein family HMM PF05768 YP_002448674.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002448675.1 identified by match to protein family HMM PF07870 YP_002448677.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838 YP_002448678.1 identified by match to protein family HMM PF07451; match to protein family HMM TIGR02845 YP_002448679.1 identified by match to protein family HMM PF03862; match to protein family HMM TIGR02839 YP_002448680.1 identified by match to protein family HMM PF07870 YP_002448681.1 identified by match to protein family HMM PF04239; match to protein family HMM PF07870 YP_002448682.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002448683.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002448684.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647 YP_002448685.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002448686.1 identified by match to protein family HMM PF03668 YP_002448687.1 identified by match to protein family HMM PF00293 YP_002448688.1 identified by match to protein family HMM PF04018 YP_002448689.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF07992; match to protein family HMM TIGR01292 YP_002448690.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002448691.1 identified by match to protein family HMM PF00132 YP_002448692.1 hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation YP_002448693.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002448694.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_002448695.1 identified by match to protein family HMM PF04020 YP_002448696.1 identified by glimmer YP_002448697.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002448698.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002448701.1 identified by match to protein family HMM PF00376 YP_002448703.1 identified by match to protein family HMM PF01381 YP_002448704.1 identified by match to protein family HMM PF03601 YP_002448705.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002448706.1 identified by match to protein family HMM PF00376 YP_002448707.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002448709.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448710.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01906 YP_002448711.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002448713.1 identified by match to protein family HMM PF00595; match to protein family HMM PF01471; match to protein family HMM PF03572; match to protein family HMM TIGR00225 YP_002448714.1 identified by match to protein family HMM PF02687 YP_002448715.1 identified by match to protein family HMM PF00005 YP_002448717.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA YP_002448718.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002448719.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741 YP_002448721.1 identified by match to protein family HMM PF00313 YP_002448723.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002448724.1 identified by match to protein family HMM PF00877 YP_002448725.1 identified by match to protein family HMM PF01638 YP_002448726.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002448727.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002448728.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002448729.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002448730.1 identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002448731.1 identified by match to protein family HMM PF00953 YP_002448732.1 identified by match to protein family HMM PF01522 YP_002448733.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF03610; match to protein family HMM PF07728 YP_002448734.1 identified by match to protein family HMM PF07452 YP_002448735.1 identified by match to protein family HMM PF02417; match to protein family HMM TIGR00937 YP_002448736.1 identified by match to protein family HMM PF04794 YP_002448737.1 identified by match to protein family HMM PF02056 YP_002448738.1 identified by match to protein family HMM PF02255 YP_002448739.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00359; match to protein family HMM TIGR00410 YP_002448740.1 identified by match to protein family HMM PF02302 YP_002448741.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002448742.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002448743.1 identified by match to protein family HMM PF02255 YP_002448744.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00359; match to protein family HMM TIGR00410 YP_002448745.1 identified by match to protein family HMM PF02302; match to protein family HMM TIGR00853 YP_002448746.1 identified by match to protein family HMM PF00375 YP_002448748.1 identified by match to protein family HMM PF00903 YP_002448749.1 identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062 YP_002448750.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002448753.1 identified by match to protein family HMM PF01654 YP_002448755.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600 YP_002448756.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002448757.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002448760.1 identified by match to protein family HMM PF06803 YP_002448761.1 identified by match to protein family HMM PF00884 YP_002448762.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448763.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_002448764.1 identified by match to protein family HMM PF00877; match to protein family HMM PF06347; match to protein family HMM PF08239 YP_002448765.1 identified by glimmer YP_002448766.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002448768.1 identified by match to protein family HMM PF00535 YP_002448769.1 identified by glimmer YP_002448770.1 identified by match to protein family HMM PF00078; match to protein family HMM PF01348 YP_002448772.1 identified by glimmer YP_002448773.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842 YP_002448774.1 identified by match to protein family HMM PF06347; match to protein family HMM PF06725; match to protein family HMM PF08239 YP_002448775.1 identified by glimmer YP_002448779.1 identified by match to protein family HMM PF04434 YP_002448780.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_002448782.1 identified by match to protein family HMM PF07872 YP_002448783.1 identified by glimmer YP_002448785.1 identified by match to protein family HMM PF06338 YP_002448786.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002448788.1 identified by match to protein family HMM PF02687 YP_002448789.1 identified by match to protein family HMM PF00005 YP_002448790.1 identified by match to protein family HMM TIGR01730 YP_002448791.1 identified by match to protein family HMM PF01381 YP_002448793.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00881 YP_002448796.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002448797.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002448798.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002448800.1 attenuator function for control of operon expression YP_002448802.1 identified by glimmer YP_002448803.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002448804.1 identified by match to protein family HMM PF00534 YP_002448805.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_002448807.1 identified by match to protein family HMM PF00534 YP_002448808.1 identified by match to protein family HMM PF07940 YP_002448809.1 identified by match to protein family HMM PF02397 YP_002448810.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_002448811.1 identified by match to protein family HMM PF02811 YP_002448812.1 identified by match to protein family HMM TIGR01007 YP_002448813.1 identified by match to protein family HMM PF02706 YP_002448814.1 identified by match to protein family HMM TIGR01007 YP_002448815.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002448816.1 identified by match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904 YP_002448818.1 identified by glimmer YP_002448819.1 identified by match to protein family HMM PF01551 YP_002448820.1 identified by match to protein family HMM PF01061 YP_002448821.1 identified by match to protein family HMM PF00005 YP_002448822.1 identified by match to protein family HMM PF00005; match to protein family HMM PF04397 YP_002448823.1 identified by match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870 YP_002448824.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002448825.1 identified by match to protein family HMM PF08680 YP_002448826.1 identified by match to protein family HMM PF06612; match to protein family HMM TIGR02327 YP_002448827.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448828.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448829.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002448830.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448831.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448832.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448833.1 Catalyzes the transfer of electrons from NADH to quinone YP_002448834.1 catalyzes the transfer of electrons from NADH to ubiquinone YP_002448835.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002448836.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002448837.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002448838.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002448839.1 identified by match to protein family HMM PF06161 YP_002448840.1 identified by match to protein family HMM PF06161 YP_002448841.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002448842.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002448843.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002448844.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002448845.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002448846.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002448847.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002448848.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002448849.1 identified by match to protein family HMM PF05468 YP_002448851.1 identified by glimmer YP_002448852.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002448853.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002448854.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440 YP_002448855.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_002448856.1 identified by match to protein family HMM PF01451 YP_002448857.1 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830 YP_002448858.1 identified by match to protein family HMM PF07681 YP_002448860.1 identified by glimmer YP_002448861.1 identified by match to protein family HMM PF02659 YP_002448862.1 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057 YP_002448864.1 identified by match to protein family HMM PF09551; match to protein family HMM TIGR02837 YP_002448865.1 identified by match to protein family HMM PF01170; match to protein family HMM PF05175; match to protein family HMM TIGR00536; match to protein family HMM TIGR03534 YP_002448866.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002448867.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002448868.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002448869.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002448870.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002448871.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002448872.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002448873.1 identified by match to protein family HMM PF00072 YP_002448875.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002448876.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_002448877.1 identified by match to protein family HMM PF00440 YP_002448878.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002448879.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002448880.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_002448881.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002448882.1 identified by match to protein family HMM PF02754 YP_002448883.1 identified by match to protein family HMM PF00614 YP_002448884.1 identified by match to protein family HMM PF03851; match to protein family HMM TIGR00629 YP_002448885.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002448886.1 identified by match to protein family HMM PF05968 YP_002448887.1 identified by match to protein family HMM PF01381 YP_002448888.1 identified by match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504 YP_002448889.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002448890.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002448891.1 identified by match to protein family HMM PF01061 YP_002448892.1 identified by match to protein family HMM PF00005 YP_002448893.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_002448894.1 identified by glimmer YP_002448895.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05737; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_002448896.1 identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389 YP_002448897.1 identified by glimmer YP_002448899.1 identified by glimmer YP_002448900.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002448901.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002448902.1 identified by match to protein family HMM PF09148 YP_002448903.1 identified by match to protein family HMM PF02016 YP_002448904.1 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655 YP_002448906.1 identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230 YP_002448907.1 identified by glimmer YP_002448908.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002448909.1 identified by match to protein family HMM PF07690 YP_002448910.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278 YP_002448911.1 identified by glimmer YP_002448912.1 identified by match to protein family HMM PF03009 YP_002448913.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002448914.1 identified by match to protein family HMM PF08741 YP_002448915.1 identified by match to protein family HMM PF02163 YP_002448916.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002448917.1 identified by match to protein family HMM PF01966 YP_002448918.1 identified by match to protein family HMM PF01497 YP_002448919.1 identified by match to protein family HMM PF00005 YP_002448920.1 identified by match to protein family HMM PF01032 YP_002448921.1 identified by match to protein family HMM PF01032 YP_002448923.1 identified by match to protein family HMM TIGR02894 YP_002448924.1 identified by match to protein family HMM PF03099 YP_002448925.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002448926.1 identified by match to protein family HMM PF06778 YP_002448927.1 identified by match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002448928.1 identified by match to protein family HMM PF07486 YP_002448929.1 identified by match to protein family HMM PF09671; match to protein family HMM TIGR02728 YP_002448930.1 identified by match to protein family HMM PF04241 YP_002448932.1 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; match to protein family HMM PF07885 YP_002448933.1 identified by match to protein family HMM PF00860 YP_002448934.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002448936.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002448938.1 identified by match to protein family HMM PF00005 YP_002448939.1 identified by match to protein family HMM PF00657 YP_002448940.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002448941.1 identified by match to protein family HMM PF02588 YP_002448942.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002448943.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002448944.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_002448945.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002448946.1 activator of nucleoside metabolism YP_002448947.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002448948.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002448949.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002448950.1 catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine YP_002448951.1 identified by match to protein family HMM PF00990; match to protein family HMM PF07694; match to protein family HMM TIGR00254 YP_002448952.1 identified by glimmer YP_002448953.1 identified by match to protein family HMM PF04328 YP_002448954.1 identified by match to protein family HMM PF02554 YP_002448955.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002448956.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002448957.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002448958.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002448959.1 identified by match to protein family HMM PF00534 YP_002448961.1 identified by match to protein family HMM PF03458 YP_002448962.1 identified by match to protein family HMM PF00015 YP_002448964.1 identified by match to protein family HMM PF03061 YP_002448965.1 identified by match to protein family HMM PF00535 YP_002448968.1 identified by match to protein family HMM PF00535 YP_002448969.1 identified by match to protein family HMM PF01943 YP_002448970.1 identified by match to protein family HMM PF09586 YP_002448971.1 identified by match to protein family HMM PF00535 YP_002448972.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_002448973.1 identified by match to protein family HMM PF00440 YP_002448974.1 identified by match to protein family HMM PF00005 YP_002448975.1 identified by match to protein family HMM PF00440 YP_002448976.1 identified by match to protein family HMM PF00873 YP_002448977.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002448978.1 identified by match to protein family HMM PF01594 YP_002448979.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases YP_002448980.1 negatively regulates murein hydrolase activity YP_002448981.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002448982.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002448983.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002448984.1 identified by match to protein family HMM PF02028 YP_002448985.1 identified by match to protein family HMM PF02898 YP_002448986.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002448987.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002448988.1 identified by match to protein family HMM PF02293 YP_002448989.1 identified by glimmer YP_002448991.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002448992.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002448993.1 identified by match to protein family HMM PF08876 YP_002448994.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880 YP_002448995.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306 YP_002448996.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002448998.1 identified by match to protein family HMM PF02012 YP_002448999.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002449000.1 identified by match to protein family HMM TIGR03187 YP_002449001.1 identified by glimmer YP_002449002.1 identified by glimmer YP_002449004.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002449005.1 identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_002449006.1 identified by glimmer YP_002449007.1 identified by glimmer YP_002449008.1 identified by glimmer YP_002449009.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002449010.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002449011.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002449013.1 identified by match to protein family HMM PF00089 YP_002449014.1 identified by match to protein family HMM PF00753 YP_002449015.1 identified by match to protein family HMM PF09648 YP_002449016.1 identified by match to protein family HMM PF07435 YP_002449017.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002449018.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002449019.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002449020.1 unwinds double stranded DNA YP_002449021.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002449022.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002449024.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002449025.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002449026.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002449027.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002449028.1 identified by match to protein family HMM PF06107 YP_002449029.1 identified by match to protein family HMM PF00924 YP_002449030.1 identified by match to protein family HMM PF06866; match to protein family HMM TIGR02841 YP_002449031.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_002449032.1 identified by match to protein family HMM PF01656 YP_002449033.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_002449034.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002449035.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002449036.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002449037.1 identified by match to protein family HMM PF01424 YP_002449038.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation YP_002449039.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002449040.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002454516.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_002454517.1 identified by glimmer; putative YP_002454518.1 identified by glimmer; putative YP_002454519.1 identified by match to protein family HMM PF05168 YP_002454520.1 identified by match to protein family HMM PF01909 YP_002454521.1 identified by glimmer; putative YP_002454522.1 identified by glimmer; putative YP_002454523.1 identified by glimmer; putative YP_002454524.1 identified by glimmer; putative YP_002454525.1 identified by glimmer; putative YP_002454526.1 identified by glimmer; putative YP_002454527.1 identified by glimmer; putative YP_002454528.1 identified by glimmer; putative YP_002454529.1 identified by glimmer; putative YP_002454531.1 identified by glimmer; putative YP_002454532.1 identified by glimmer; putative YP_002454533.1 identified by glimmer; putative YP_002454534.1 identified by glimmer; putative YP_002454536.1 identified by glimmer; putative YP_002454537.1 identified by glimmer; putative YP_002454538.1 identified by glimmer; putative YP_002454539.1 identified by glimmer; putative YP_002454540.1 identified by glimmer; putative YP_002454546.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002454547.1 identified by glimmer; putative YP_002454548.1 identified by glimmer; putative YP_002454550.1 identified by glimmer; putative YP_002454551.1 identified by glimmer; putative YP_002454554.1 identified by glimmer; putative YP_002454555.1 identified by glimmer; putative YP_002454556.1 identified by glimmer; putative YP_002454557.1 identified by glimmer; putative YP_002454560.1 identified by glimmer; putative YP_002454561.1 identified by glimmer; putative YP_002454562.1 identified by glimmer; putative YP_002454563.1 identified by glimmer; putative YP_002454566.1 identified by glimmer; putative YP_002454567.1 identified by match to protein family HMM PF00041 YP_002454568.1 identified by glimmer; putative YP_002454569.1 identified by glimmer; putative YP_002454570.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454571.1 identified by glimmer; putative YP_002454573.1 identified by glimmer; putative YP_002454574.1 identified by glimmer; putative YP_002454575.1 identified by match to protein family HMM PF00754 YP_002454576.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002454577.1 identified by glimmer; putative YP_002454579.1 identified by match to protein family HMM PF00041 YP_002454581.1 identified by match to protein family HMM PF07691 YP_002454583.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002454585.1 identified by glimmer; putative YP_002454586.1 identified by glimmer; putative YP_002454587.1 identified by glimmer; putative YP_002454588.1 identified by glimmer; putative YP_002454590.1 identified by glimmer; putative YP_002454592.1 identified by glimmer; putative YP_002454593.1 identified by glimmer; putative YP_002454594.1 identified by glimmer; putative YP_002454596.1 identified by glimmer; putative YP_002454597.1 identified by glimmer; putative YP_002454598.1 identified by glimmer; putative YP_002454599.1 identified by glimmer; putative YP_002454600.1 identified by glimmer; putative YP_002454601.1 identified by glimmer; putative YP_002454602.1 identified by match to protein family HMM PF00082 YP_002454603.1 identified by glimmer; putative YP_002454604.1 identified by glimmer; putative YP_002454605.1 identified by glimmer; putative YP_002454607.1 identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594 YP_002454608.1 identified by glimmer; putative YP_002454610.1 identified by match to protein family HMM PF01471; match to protein family HMM PF01510 YP_002454611.1 identified by glimmer; putative YP_002454612.1 identified by glimmer; putative YP_002454614.1 identified by glimmer; putative YP_002454615.1 identified by glimmer; putative YP_002454616.1 identified by glimmer; putative YP_002454617.1 identified by glimmer; putative YP_002454618.1 identified by glimmer; putative YP_002454619.1 identified by glimmer; putative YP_002454620.1 identified by glimmer; putative YP_002454621.1 identified by glimmer; putative YP_002454622.1 identified by glimmer; putative YP_002454623.1 identified by glimmer; putative YP_002454624.1 identified by match to protein family HMM PF00376 YP_002454625.1 identified by glimmer; putative YP_002454626.1 identified by glimmer; putative YP_002454627.1 identified by match to protein family HMM TIGR00621 YP_002454628.1 identified by glimmer; putative YP_002454629.1 identified by glimmer; putative YP_002454630.1 identified by glimmer; putative YP_002454631.1 identified by glimmer; putative YP_002454632.1 identified by glimmer; putative YP_002454633.1 identified by glimmer; putative YP_002454634.1 identified by match to protein family HMM PF00149 YP_002454635.1 identified by glimmer; putative YP_002454636.1 identified by glimmer; putative YP_002454637.1 identified by glimmer; putative YP_002454639.1 identified by glimmer; putative YP_002454640.1 identified by glimmer; putative YP_002454641.1 identified by glimmer; putative YP_002454642.1 identified by glimmer; putative YP_002454643.1 identified by glimmer; putative YP_002454644.1 identified by glimmer; putative YP_002454645.1 identified by glimmer; putative YP_002454646.1 identified by glimmer; putative YP_002454648.1 identified by match to protein family HMM PF00395 YP_002454651.1 identified by glimmer; putative YP_002454652.1 identified by glimmer; putative YP_002454653.1 identified by glimmer; putative YP_002454654.1 identified by glimmer; putative YP_002454656.1 identified by match to protein family HMM PF00436 YP_002454658.1 identified by glimmer; putative YP_002454660.1 identified by glimmer; putative YP_002454661.1 identified by glimmer; putative YP_002454662.1 identified by glimmer; putative YP_002454663.1 identified by glimmer; putative YP_002454665.1 identified by glimmer; putative YP_002454666.1 identified by glimmer; putative YP_002454667.1 identified by glimmer; putative YP_002454668.1 identified by glimmer; putative YP_002454669.1 identified by glimmer; putative YP_002454670.1 identified by match to protein family HMM PF00271 YP_002454671.1 identified by glimmer; putative YP_002454673.1 identified by match to protein family HMM PF02518 YP_002454674.1 identified by match to protein family HMM PF00072 YP_002454675.1 identified by match to protein family HMM PF01381 YP_002454676.1 identified by glimmer; putative YP_002454677.1 identified by glimmer; putative YP_002454678.1 identified by glimmer; putative YP_002454680.1 identified by glimmer; putative YP_002454681.1 identified by match to protein family HMM PF00004; match to protein family HMM TIGR02397 YP_002454682.1 identified by glimmer; putative YP_002454684.1 identified by glimmer; putative YP_002454685.1 identified by glimmer; putative YP_002454686.1 identified by glimmer; putative YP_002454689.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002454691.1 identified by glimmer; putative YP_002454694.1 identified by match to protein family HMM PF03738 YP_002454695.1 identified by glimmer; putative YP_002454696.1 identified by match to protein family HMM PF00565 YP_002454698.1 identified by glimmer; putative YP_002454700.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002454701.1 identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937 YP_002454704.1 identified by glimmer; putative YP_002454705.1 identified by glimmer; putative YP_002454706.1 identified by glimmer; putative YP_002454707.1 identified by glimmer; putative YP_002454708.1 identified by glimmer; putative YP_002454709.1 identified by match to protein family HMM PF06144; match to protein family HMM TIGR01128 YP_002454710.1 identified by glimmer; putative YP_002454712.1 identified by match to protein family HMM PF01423 YP_002454713.1 identified by glimmer; putative YP_002454714.1 identified by glimmer; putative YP_002454715.1 identified by glimmer; putative YP_002454716.1 identified by glimmer; putative YP_002454718.1 identified by match to protein family HMM PF01022 YP_002454720.1 identified by glimmer; putative YP_002454722.1 identified by glimmer; putative YP_002454723.1 identified by match to protein family HMM PF00589 YP_002454724.1 identified by match to protein family HMM PF02810; match to protein family HMM PF03692 YP_002454725.1 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439 YP_002454726.1 identified by glimmer; putative YP_002454727.1 identified by match to protein family HMM PF02086 YP_002454729.1 identified by glimmer; putative YP_002454730.1 identified by glimmer; putative YP_002454731.1 identified by match to protein family HMM PF00269 YP_002454735.1 identified by glimmer; putative YP_002454736.1 identified by glimmer; putative YP_002454737.1 identified by glimmer; putative YP_002454738.1 identified by match to protein family HMM PF06013 YP_002454740.1 identified by match to protein family HMM PF00216 YP_002454744.1 identified by glimmer; putative YP_002454745.1 identified by glimmer; putative YP_002454746.1 identified by glimmer; putative YP_002454747.1 identified by glimmer; putative YP_002454748.1 identified by glimmer; putative YP_002454750.1 identified by glimmer; putative YP_002454751.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002454752.1 identified by match to protein family HMM PF08645; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662 YP_002454754.1 identified by glimmer; putative YP_002454755.1 identified by glimmer; putative YP_002454756.1 identified by glimmer; putative YP_002454758.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00580 YP_002454759.1 identified by match to protein family HMM TIGR00678 YP_002454760.1 identified by glimmer; putative YP_002454761.1 identified by glimmer; putative YP_002454762.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by glimmer; putative YP_002454763.1 identified by glimmer; putative YP_002454764.1 identified by glimmer; putative YP_002454766.1 identified by glimmer; putative YP_002454767.1 identified by glimmer; putative YP_002454768.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002454769.1 identified by match to protein family HMM PF00565 YP_002454772.1 identified by match to protein family HMM PF00639 YP_002454773.1 identified by glimmer; putative YP_002454774.1 identified by glimmer; putative YP_002454778.1 identified by match to protein family HMM PF09643 YP_002454781.1 identified by glimmer; putative YP_002454782.1 identified by glimmer; putative YP_002454783.1 identified by glimmer; putative YP_002454784.1 identified by match to protein family HMM PF00145 YP_002454785.1 identified by glimmer; putative YP_002454786.1 identified by glimmer; putative YP_002454787.1 identified by glimmer; putative YP_002454789.1 identified by glimmer; putative YP_002454791.1 identified by match to protein family HMM PF01423; match to protein family HMM TIGR02383 YP_002454792.1 identified by glimmer; putative YP_002454793.1 identified by match to protein family HMM PF01022 YP_002454794.1 identified by glimmer; putative YP_002454795.1 identified by glimmer; putative YP_002454797.1 identified by glimmer; putative YP_002454798.1 identified by match to protein family HMM PF02481 YP_002454799.1 identified by glimmer; putative YP_002454800.1 identified by glimmer; putative YP_002454802.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_002454803.1 identified by glimmer; putative YP_002454805.1 identified by match to protein family HMM PF08863 YP_002454806.1 identified by match to protein family HMM PF00817 YP_002454808.1 identified by glimmer; putative YP_002454811.1 identified by glimmer; putative YP_002454812.1 identified by glimmer; putative YP_002454813.1 identified by glimmer; putative YP_002454816.1 identified by glimmer; putative YP_002454817.1 identified by glimmer; putative YP_002454820.1 identified by glimmer; putative YP_002454821.1 identified by glimmer; putative YP_002454822.1 identified by glimmer; putative YP_002454823.1 identified by glimmer; putative YP_002454824.1 identified by glimmer; putative YP_002454827.1 identified by glimmer; putative YP_002454829.1 identified by glimmer; putative YP_002454830.1 identified by glimmer; putative YP_002454831.1 identified by glimmer; putative YP_002454832.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01396 YP_002454833.1 identified by glimmer; putative YP_002454835.1 identified by match to protein family HMM PF00004 YP_002454836.1 identified by glimmer; putative YP_002454837.1 identified by glimmer; putative YP_002454838.1 identified by match to protein family HMM PF00877 YP_002454840.1 identified by match to protein family HMM PF00877; match to protein family HMM PF01551; match to protein family HMM PF06725 YP_002454841.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002454845.1 identified by glimmer; putative YP_002454846.1 identified by glimmer; putative YP_002454847.1 identified by glimmer; putative YP_002454849.1 identified by glimmer; putative YP_002454850.1 identified by glimmer; putative YP_002454851.1 identified by match to protein family HMM PF00712; match to protein family HMM PF02767; match to protein family HMM PF02768; match to protein family HMM TIGR00663 YP_002454852.1 identified by glimmer; putative YP_002454853.1 identified by glimmer; putative YP_002454854.1 identified by glimmer; putative YP_002454856.1 identified by match to protein family HMM PF00899 YP_002454857.1 identified by glimmer; putative YP_002454858.1 identified by glimmer; putative YP_002454860.1 identified by glimmer; putative YP_002454865.1 identified by match to protein family HMM PF00437 YP_002454867.1 identified by match to protein family HMM PF08666 YP_002454868.1 identified by glimmer; putative YP_002454869.1 identified by glimmer; putative YP_002454870.1 identified by glimmer; putative YP_002454871.1 identified by glimmer; putative YP_002454876.1 identified by glimmer; putative YP_002454877.1 identified by glimmer; putative YP_002454879.1 identified by glimmer; putative YP_002454881.1 identified by match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665