-- dump date   	20140618_221218
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002527822.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_002527823.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002527824.1	Code: S; COG: COG2501
YP_002527825.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_002527826.1	negatively supercoils closed circular double-stranded DNA
YP_002527827.1	negatively supercoils closed circular double-stranded DNA
YP_002527830.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002527831.1	Code: M; COG: COG1686
YP_002527832.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
YP_002527833.1	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
YP_002527834.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002527836.1	Code: F; COG: COG1428
YP_002527837.1	Code: F; COG: COG1428
YP_002527838.1	Code: Q; COG: COG1335
YP_002527839.1	Code: FJ; COG: COG0590
YP_002527840.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002527842.1	Code: S; COG: COG0718
YP_002527843.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_002527848.1	Code: E; COG: COG1982
YP_002527849.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_002527850.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_002527851.1	Code: S; COG: COG1774
YP_002527852.1	in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA
YP_002527853.1	Code: R; COG: COG4123
YP_002527854.1	Code: L; COG: COG2827
YP_002527855.1	Code: R; COG: COG0313
YP_002527856.1	Code: K; COG: COG2002
YP_002527857.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002527858.1	Code: L; COG: COG0084
YP_002527859.1	Code: L; COG: COG1658
YP_002527860.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002527862.1	Code: S; COG: COG4466
YP_002527864.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_002527865.1	Code: F; COG: COG0503
YP_002527866.1	Code: J; COG: COG0251
YP_002527867.1	stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
YP_002527868.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_002527869.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_002527870.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002527872.1	Code: LK; COG: COG1197
YP_002527873.1	Code: K; COG: COG2002
YP_002527874.1	Code: R; COG: COG2244
YP_002527875.1	Code: R; COG: COG3956
YP_002527876.1	Code: J; COG: COG1188
YP_002527879.1	Code: D; COG: COG2919
YP_002527880.1	Code: J; COG: COG1098
YP_002527881.1	Code: TK; COG: COG2208
YP_002527882.1	Code: D; COG: COG0037
YP_002527883.1	Code: F; COG: COG0634
YP_002527884.1	Code: O; COG: COG0465
YP_002527885.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_002527886.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_002527887.1	Code: E; COG: COG0031
YP_002527888.1	Code: EH; COG: COG0147
YP_002527889.1	amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis
YP_002527890.1	catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate
YP_002527891.1	Code: H; COG: COG0294
YP_002527892.1	Code: H; COG: COG1539
YP_002527893.1	Code: H; COG: COG0801
YP_002527894.1	Code: K; COG: COG1396
YP_002527895.1	Code: J; COG: COG0042
YP_002527896.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002527899.1	Code: K; COG: COG4463
YP_002527900.1	Code: S; COG: COG3880
YP_002527901.1	Code: E; COG: COG3869
YP_002527902.1	Code: O; COG: COG0542
YP_002527903.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_002527904.1	non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair
YP_002527905.1	Code: R; COG: COG4956
YP_002527906.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_002527907.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_002527908.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002527909.1	Code: E; COG: COG1045
YP_002527910.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002527911.1	Code: S; COG: COG1939
YP_002527912.1	Code: J; COG: COG0566
YP_002527913.1	Code: R; COG: COG3688
YP_002527914.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002527915.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002527916.1	Modulates Rho-dependent transcription termination
YP_002527917.1	Code: J; COG: COG0080
YP_002527918.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002527919.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002527920.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_002527921.1	Code: J; COG: COG2813
YP_002527922.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002527923.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002527924.1	Code: J; COG: COG1358
YP_002527925.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002527926.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002527927.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002527928.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002527929.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002527930.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002527931.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002527932.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002527933.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002527934.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002527935.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002527936.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002527937.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002527938.1	one of the stabilizing components for the large ribosomal subunit
YP_002527939.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002527940.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002527941.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002527942.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002527943.1	Code: J; COG: COG0199
YP_002527944.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002527945.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002527946.1	binds 5S rRNA along with protein L5 and L25
YP_002527947.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002527948.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002527949.1	late assembly protein
YP_002527950.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002527951.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002527952.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_002527953.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002527954.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_002527955.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002527956.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002527957.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002527958.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002527959.1	with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene
YP_002527960.1	with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene
YP_002527961.1	Code: P; COG: COG0619
YP_002527962.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002527963.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002527964.1	forms a direct contact with the tRNA during translation
YP_002527966.1	Code: M; COG: COG0860
YP_002527967.1	Code: D; COG: COG0489
YP_002527970.1	Code: G; COG: COG0726
YP_002527973.1	Code: G; COG: COG1929
YP_002527974.1	Code: E; COG: COG0010
YP_002527975.1	Code: S; COG: COG1624
YP_002527977.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_002527978.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_002527979.1	Code: R; COG: COG0596
YP_002527980.1	Code: K; COG: COG1802
YP_002527981.1	Code: G; COG: COG1070
YP_002527982.1	Code: GE; COG: COG2610
YP_002527983.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002527986.1	Code: S; COG: COG2259
YP_002527990.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002527991.1	Code: P; COG: COG2011
YP_002527992.1	Code: P; COG: COG1135
YP_002527993.1	Code: P; COG: COG1464
YP_002527994.1	Code: CR; COG: COG0604
YP_002527996.1	Code: C; COG: COG0277
YP_002527997.1	Code: GEPR; COG: COG0477
YP_002527999.1	Code: GEPR; COG: COG0477
YP_002528003.1	Code: EP; COG: COG0601
YP_002528004.1	Code: EP; COG: COG1173
YP_002528005.1	Code: EP; COG: COG0444
YP_002528006.1	Code: E; COG: COG4608
YP_002528007.1	Code: E; COG: COG4166
YP_002528009.1	Code: K; COG: COG2207
YP_002528010.1	Code: K; COG: COG1309
YP_002528012.1	Code: E; COG: COG4166
YP_002528013.1	Code: E; COG: COG4166
YP_002528014.1	Code: R; COG: COG0656
YP_002528015.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002528016.1	Code: H; COG: COG3201
YP_002528017.1	Code: G; COG: COG4975
YP_002528018.1	Code: P; COG: COG4149
YP_002528019.1	Code: P; COG: COG0725
YP_002528020.1	Code: P; COG: COG1910
YP_002528023.1	Code: K; COG: COG0583
YP_002528024.1	Code: GER; COG: COG0697
YP_002528028.1	Code: I; COG: COG0204
YP_002528030.1	Code: K; COG: COG1609
YP_002528031.1	Code: S; COG: COG1284
YP_002528033.1	Code: L; COG: COG0084
YP_002528034.1	Code: S; COG: COG5298
YP_002528036.1	Code: C; COG: COG1085
YP_002528041.1	Code: E; COG: COG0747
YP_002528042.1	Code: E; COG: COG0747
YP_002528043.1	Code: EP; COG: COG0601
YP_002528044.1	Code: EP; COG: COG1173
YP_002528045.1	Code: EP; COG: COG0444
YP_002528046.1	Code: E; COG: COG4608
YP_002528047.1	Code: R; COG: COG0561
YP_002528051.1	Code: ER; COG: COG3185
YP_002528052.1	Code: Q; COG: COG0179
YP_002528053.1	Code: Q; COG: COG3508
YP_002528054.1	Code: E; COG: COG0531
YP_002528056.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002528057.1	Code: M; COG: COG0770
YP_002528058.1	Code: LKJ; COG: COG0513
YP_002528059.1	Code: L; COG: COG4294
YP_002528060.1	Code: R; COG: COG0705
YP_002528061.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_002528062.1	Code: M; COG: COG2834
YP_002528063.1	Code: M; COG: COG0787
YP_002528064.1	Code: K; COG: COG0864
YP_002528065.1	Code: T; COG: COG2337
YP_002528066.1	Code: K; COG: COG2183
YP_002528067.1	Code: S; COG: COG3091
YP_002528069.1	Code: R; COG: COG0802
YP_002528070.1	Code: O; COG: COG1214
YP_002528071.1	Code: R; COG: COG0456
YP_002528072.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002528073.1	Code: R; COG: COG0488
YP_002528074.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_002528075.1	Code: R; COG: COG1266
YP_002528076.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002528077.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002528078.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002528079.1	Code: R; COG: COG2252
YP_002528080.1	Code: TK; COG: COG0745
YP_002528081.1	Code: T; COG: COG0642
YP_002528084.1	Code: Q; COG: COG2761
YP_002528090.1	Code: MG; COG: COG0451
YP_002528094.1	Code: KE; COG: COG1167
YP_002528095.1	Code: E; COG: COG0506
YP_002528100.1	Code: L; COG: COG2801
YP_002528104.1	Code: F; COG: COG0041
YP_002528105.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_002528106.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002528107.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_002528108.1	With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway
YP_002528109.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002528110.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002528111.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_002528112.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_002528113.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_002528114.1	involved in de novo purine biosynthesis
YP_002528115.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_002528116.1	Code: S; COG: COG4877
YP_002528117.1	Code: O; COG: COG0330
YP_002528119.1	PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer
YP_002528120.1	Code: L; COG: COG0210
YP_002528121.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_002528122.1	Code: R; COG: COG4851
YP_002528123.1	Code: R; COG: COG0730
YP_002528124.1	catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate
YP_002528126.1	Code: Q; COG: COG1335
YP_002528127.1	Code: P; COG: COG1135
YP_002528128.1	Code: P; COG: COG2011
YP_002528129.1	Code: P; COG: COG1464
YP_002528131.1	Code: P; COG: COG0003
YP_002528132.1	Code: K; COG: COG1846
YP_002528133.1	Code: S; COG: COG4682
YP_002528134.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_002528135.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002528136.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002528137.1	similar to YegS from E. coli
YP_002528138.1	Code: M; COG: COG2230
YP_002528139.1	Code: R; COG: COG0546
YP_002528140.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_002528141.1	Code: KT; COG: COG3829
YP_002528142.1	Code: C; COG: COG1012
YP_002528143.1	Code: P; COG: COG2076
YP_002528144.1	Code: E; COG: COG2309
YP_002528145.1	Code: G; COG: COG0726
YP_002528146.1	Code: F; COG: COG1972
YP_002528147.1	Code: J; COG: COG2265
YP_002528148.1	Code: J; COG: COG0042
YP_002528150.1	Code: EH; COG: COG0028
YP_002528152.1	Code: S; COG: COG4807
YP_002528161.1	Code: L; COG: COG4584
YP_002528162.1	Code: L; COG: COG1484
YP_002528164.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002528165.1	Code: O; COG: COG1225
YP_002528168.1	Code: L; COG: COG2801
YP_002528169.1	Code: L; COG: COG2963
YP_002528170.1	Code: S; COG: COG4807
YP_002528171.1	Code: R; COG: COG1451
YP_002528173.1	Code: MR; COG: COG4948
YP_002528175.1	Code: C; COG: COG1757
YP_002528176.1	Code: R; COG: COG1473
YP_002528178.1	Code: O; COG: COG3634
YP_002528179.1	Code: O; COG: COG0450
YP_002528180.1	related protein from Bacillus subtilis functions as methylribose kinase and functions in salvage pathway
YP_002528181.1	isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway
YP_002528182.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_002528185.1	Code: P; COG: COG0609
YP_002528186.1	Code: P; COG: COG0609
YP_002528187.1	Code: P; COG: COG0614
YP_002528188.1	Code: O; COG: COG0492
YP_002528196.1	Code: R; COG: COG1878
YP_002528198.1	Code: R; COG: COG3541
YP_002528199.1	Code: GEPR; COG: COG0477
YP_002528200.1	Code: E; COG: COG0665
YP_002528201.1	Code: I; COG: COG3239
YP_002528205.1	Code: E; COG: COG0765
YP_002528206.1	Code: ET; COG: COG0834
YP_002528207.1	Code: E; COG: COG1126
YP_002528208.1	Code: NT; COG: COG0840
YP_002528209.1	Code: G; COG: COG0366
YP_002528210.1	Code: G; COG: COG1263
YP_002528211.1	Code: R; COG: COG3568
YP_002528212.1	Code: S; COG: COG1511
YP_002528213.1	decatenates replicating daughter chromosomes
YP_002528214.1	Code: K; COG: COG1695
YP_002528215.1	Code: V; COG: COG0577
YP_002528216.1	Code: V; COG: COG1136
YP_002528221.1	Code: V; COG: COG1131
YP_002528225.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
YP_002528226.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
YP_002528228.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
YP_002528229.1	Code: NT; COG: COG0840
YP_002528230.1	Code: S; COG: COG0011
YP_002528231.1	Code: P; COG: COG0600
YP_002528232.1	Code: P; COG: COG0715
YP_002528233.1	Code: P; COG: COG1116
YP_002528235.1	Code: R; COG: COG0488
YP_002528236.1	Code: G; COG: COG3325
YP_002528238.1	Code: OC; COG: COG0526
YP_002528243.1	Code: K; COG: COG1476
YP_002528245.1	Code: R; COG: COG2270
YP_002528246.1	Code: R; COG: COG1524
YP_002528248.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002528250.1	Code: KG; COG: COG1940
YP_002528251.1	Code: T; COG: COG2310
YP_002528252.1	Code: T; COG: COG2310
YP_002528253.1	Code: T; COG: COG2310
YP_002528254.1	Code: P; COG: COG0861
YP_002528256.1	Code: P; COG: COG3853
YP_002528257.1	Code: P; COG: COG0474
YP_002528258.1	Code: S; COG: COG4840
YP_002528259.1	Code: T; COG: COG0394
YP_002528261.1	Code: S; COG: COG1295
YP_002528262.1	Code: P; COG: COG2217
YP_002528263.1	Code: GER; COG: COG0697
YP_002528266.1	Code: U; COG: COG0681
YP_002528268.1	Code: S; COG: COG0586
YP_002528269.1	Code: S; COG: COG2510
YP_002528271.1	Code: R; COG: COG3871
YP_002528272.1	Code: P; COG: COG0387
YP_002528276.1	Code: C; COG: COG1951
YP_002528277.1	Code: G; COG: COG0726
YP_002528278.1	Code: L; COG: COG0122
YP_002528279.1	Code: J; COG: COG2265
YP_002528280.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002528284.1	Code: KT; COG: COG3829
YP_002528286.1	Code: E; COG: COG0833
YP_002528287.1	catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine
YP_002528289.1	Code: S; COG: COG1971
YP_002528292.1	catalyzes the formation of glutamate from glutamine
YP_002528293.1	Code: G; COG: COG1263
YP_002528294.1	Code: V; COG: COG1680
YP_002528298.1	Code: M; COG: COG0677
YP_002528299.1	Code: MG; COG: COG0451
YP_002528301.1	Code: C; COG: COG1882
YP_002528302.1	Code: O; COG: COG1180
YP_002528303.1	processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids
YP_002528306.1	Code: Q; COG: COG1228
YP_002528307.1	Code: R; COG: COG1090
YP_002528308.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_002528311.1	SASP K; found in the forespore compartment
YP_002528313.1	Code: R; COG: COG1988
YP_002528314.1	Code: L; COG: COG1194
YP_002528319.1	Code: J; COG: COG3557
YP_002528320.1	Code: V; COG: COG1132
YP_002528321.1	Code: S; COG: COG4129
YP_002528323.1	converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate
YP_002528324.1	Code: R; COG: COG4586
YP_002528326.1	Code: R; COG: COG3694
YP_002528327.1	Code: P; COG: COG1226
YP_002528328.1	Code: O; COG: COG1225
YP_002528329.1	similar to peroxide operon regulator in B.subtilis; Code: P; COG: COG0735
YP_002528342.1	Code: L; COG: COG1961
YP_002528351.1	Code: S; COG: COG0217
YP_002528352.1	Code: LR; COG: COG0494
YP_002528354.1	Code: O; COG: COG1651
YP_002528356.1	Code: C; COG: COG1600
YP_002528358.1	Code: J; COG: COG0219
YP_002528361.1	Code: T; COG: COG2766
YP_002528362.1	Code: S; COG: COG2718
YP_002528364.1	Code: M; COG: COG1292
YP_002528367.1	Code: S; COG: COG2268
YP_002528368.1	Code: NT; COG: COG0840
YP_002528369.1	Code: T; COG: COG3290
YP_002528370.1	Code: KT; COG: COG4565
YP_002528371.1	Code: C; COG: COG2851
YP_002528374.1	Code: R; COG: COG0666
YP_002528376.1	Code: K; COG: COG1954
YP_002528377.1	Code: G; COG: COG3839
YP_002528378.1	Code: G; COG: COG1175
YP_002528379.1	Code: G; COG: COG0395
YP_002528380.1	Code: G; COG: COG1653
YP_002528381.1	Code: T; COG: COG0639
YP_002528382.1	Code: TK; COG: COG0745
YP_002528383.1	Code: T; COG: COG0642
YP_002528385.1	Code: S; COG: COG4990
YP_002528386.1	Code: NT; COG: COG0840
YP_002528387.1	C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration
YP_002528388.1	Code: KT; COG: COG4565
YP_002528389.1	Code: C; COG: COG3493
YP_002528390.1	Code: C; COG: COG0281
YP_002528392.1	Code: GER; COG: COG0697
YP_002528393.1	Code: KE; COG: COG1167
YP_002528394.1	Code: KR; COG: COG0454
YP_002528395.1	Code: T; COG: COG0642
YP_002528396.1	Code: TK; COG: COG0745
YP_002528398.1	Code: KR; COG: COG0454
YP_002528399.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
YP_002528400.1	Code: R; COG: COG3383
YP_002528401.1	Code: S; COG: COG2427
YP_002528403.1	Code: E; COG: COG0686
YP_002528404.1	Code: E; COG: COG0531
YP_002528405.1	Code: K; COG: COG0640
YP_002528407.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_002528410.1	Code: E; COG: COG3227
YP_002528415.1	Code: K; COG: COG1316
YP_002528416.1	Code: F; COG: COG1972
YP_002528417.1	Code: E; COG: COG0346
YP_002528418.1	Code: R; COG: COG1253
YP_002528419.1	catalyzes the formation of fumarate from aspartate
YP_002528421.1	Code: C; COG: COG1620
YP_002528422.1	Code: K; COG: COG0640
YP_002528423.1	SASP H; spore coat; expressed in forespore compartment
YP_002528424.1	Code: E; COG: COG3104
YP_002528425.1	Code: P; COG: COG0614
YP_002528426.1	Code: P; COG: COG0609
YP_002528427.1	Code: P; COG: COG0609
YP_002528428.1	Code: PH; COG: COG1120
YP_002528429.1	Code: QR; COG: COG0500
YP_002528430.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
YP_002528431.1	Code: MG; COG: COG0451
YP_002528432.1	Code: F; COG: COG0461
YP_002528434.1	Code: P; COG: COG4548
YP_002528435.1	Code: R; COG: COG0714
YP_002528436.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
YP_002528440.1	Code: E; COG: COG0531
YP_002528441.1	Code: K; COG: COG2188
YP_002528442.1	Code: G; COG: COG1264
YP_002528444.1	Code: G; COG: COG1263
YP_002528445.1	Code: G; COG: COG0366
YP_002528450.1	Code: R; COG: COG2334
YP_002528451.1	Code: E; COG: COG1115
YP_002528452.1	Code: E; COG: COG1126
YP_002528453.1	Code: ET; COG: COG0834
YP_002528454.1	Code: E; COG: COG0765
YP_002528455.1	Code: E; COG: COG0765
YP_002528456.1	Code: E; COG: COG0833
YP_002528457.1	Code: O; COG: COG1765
YP_002528458.1	Code: FGR; COG: COG0537
YP_002528459.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002528460.1	similar to AAP07663.1
YP_002528461.1	Code: K; COG: COG2378
YP_002528462.1	Code: H; COG: COG0262
YP_002528463.1	Code: T; COG: COG0642
YP_002528464.1	Code: TK; COG: COG0745
YP_002528466.1	Code: P; COG: COG0659
YP_002528467.1	Code: T; COG: COG0589
YP_002528469.1	Code: E; COG: COG0747
YP_002528470.1	Code: EP; COG: COG1173
YP_002528471.1	Code: EP; COG: COG0601
YP_002528472.1	Code: E; COG: COG4608
YP_002528473.1	Code: EP; COG: COG0444
YP_002528474.1	Code: G; COG: COG2271
YP_002528475.1	Code: K; COG: COG1846
YP_002528476.1	Code: GEPR; COG: COG0477
YP_002528477.1	Code: K; COG: COG1609
YP_002528478.1	Code: G; COG: COG0524
YP_002528479.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
YP_002528481.1	Code: G; COG: COG1172
YP_002528482.1	Code: G; COG: COG1879
YP_002528483.1	similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity
YP_002528484.1	Code: S; COG: COG4412
YP_002528485.1	Code: GEPR; COG: COG0477
YP_002528486.1	Code: ER; COG: COG1063
YP_002528487.1	Code: P; COG: COG1226
YP_002528489.1	Code: L; COG: COG0675
YP_002528491.1	Code: E; COG: COG3616
YP_002528492.1	Code: C; COG: COG0277
YP_002528493.1	Code: V; COG: COG4767
YP_002528495.1	phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002528498.1	Code: K; COG: COG1476
YP_002528500.1	Code: M; COG: COG3764
YP_002528502.1	Code: E; COG: COG3104
YP_002528504.1	Code: E; COG: COG1114
YP_002528507.1	Code: E; COG: COG1113
YP_002528508.1	Code: R; COG: COG2252
YP_002528509.1	Code: K; COG: COG1476
YP_002528512.1	Code: KR; COG: COG0454
YP_002528513.1	Code: P; COG: COG0475
YP_002528514.1	Code: C; COG: COG3125
YP_002528515.1	Code: C; COG: COG1845
YP_002528516.1	Code: C; COG: COG0843
YP_002528517.1	Code: C; COG: COG1622
YP_002528518.1	Code: E; COG: COG0833
YP_002528519.1	Code: S; COG: COG4990
YP_002528520.1	Code: R; COG: COG1473
YP_002528522.1	Code: ER; COG: COG0591
YP_002528527.1	Code: P; COG: COG0370
YP_002528529.1	Code: P; COG: COG1918
YP_002528530.1	Code: P; COG: COG0226
YP_002528531.1	Code: P; COG: COG0573
YP_002528532.1	Code: P; COG: COG0581
YP_002528533.1	Code: V; COG: COG0841
YP_002528535.1	Code: R; COG: COG0517
YP_002528538.1	Code: K; COG: COG0819
YP_002528539.1	Code: P; COG: COG1116
YP_002528540.1	Code: P; COG: COG0600
YP_002528541.1	Code: P; COG: COG0715
YP_002528542.1	regulates the production of extracellular enzymes
YP_002528543.1	Code: E; COG: COG0665
YP_002528544.1	with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate
YP_002528545.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002528546.1	catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways
YP_002528547.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_002528551.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002528552.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002528553.1	one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex
YP_002528554.1	Code: T; COG: COG2205
YP_002528556.1	Code: K; COG: COG1846
YP_002528557.1	Code: R; COG: COG4667
YP_002528561.1	Code: V; COG: COG1136
YP_002528563.1	Code: G; COG: COG1172
YP_002528564.1	Code: G; COG: COG1129
YP_002528565.1	Code: G; COG: COG1879
YP_002528566.1	Code: R; COG: COG2252
YP_002528567.1	Code: IQR; COG: COG1028
YP_002528571.1	Code: OC; COG: COG0526
YP_002528572.1	Code: O; COG: COG1495
YP_002528579.1	Code: C; COG: COG0778
YP_002528580.1	Code: S; COG: COG2719
YP_002528583.1	Code: R; COG: COG0446
YP_002528584.1	Code: S; COG: COG1937
YP_002528586.1	Code: R; COG: COG0491
YP_002528587.1	Code: O; COG: COG0425
YP_002528588.1	Code: O; COG: COG0425
YP_002528589.1	Code: P; COG: COG0607
YP_002528590.1	Code: P; COG: COG0607
YP_002528591.1	Code: S; COG: COG2210
YP_002528592.1	Code: R; COG: COG0730
YP_002528594.1	Code: K; COG: COG1316
YP_002528595.1	Code: CR; COG: COG0604
YP_002528596.1	Code: P; COG: COG1283
YP_002528597.1	Code: GEPR; COG: COG0477
YP_002528598.1	Code: S; COG: COG3589
YP_002528599.1	Code: K; COG: COG3711
YP_002528600.1	Code: G; COG: COG1447
YP_002528601.1	Code: G; COG: COG1440
YP_002528602.1	Code: G; COG: COG1455
YP_002528604.1	Code: S; COG: COG3589
YP_002528607.1	Code: V; COG: COG0577
YP_002528608.1	Code: V; COG: COG1136
YP_002528610.1	Code: S; COG: COG5522
YP_002528612.1	Code: EP; COG: COG1173
YP_002528613.1	Code: E; COG: COG1114
YP_002528614.1	Code: P; COG: COG3546
YP_002528619.1	Code: S; COG: COG1273
YP_002528620.1	Code: S; COG: COG3339
YP_002528621.1	Code: S; COG: COG0586
YP_002528627.1	Code: E; COG: COG0531
YP_002528628.1	Code: P; COG: COG0475
YP_002528630.1	Code: K; COG: COG1737
YP_002528631.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
YP_002528632.1	Code: G; COG: COG1263
YP_002528633.1	Code: S; COG: COG3589
YP_002528634.1	Code: S; COG: COG2259
YP_002528635.1	Code: R; COG: COG3631
YP_002528638.1	Code: K; COG: COG1522
YP_002528639.1	catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate
YP_002528640.1	Code: P; COG: COG2076
YP_002528641.1	Code: P; COG: COG2076
YP_002528642.1	Code: K; COG: COG1309
YP_002528643.1	Code: GEPR; COG: COG0477
YP_002528644.1	Code: K; COG: COG1733
YP_002528645.1	Code: R; COG: COG5485
YP_002528646.1	Code: R; COG: COG2249
YP_002528647.1	Code: R; COG: COG4533
YP_002528648.1	Code: GEPR; COG: COG0477
YP_002528650.1	Code: R; COG: COG0693
YP_002528651.1	Code: P; COG: COG0753
YP_002528653.1	Code: E; COG: COG0531
YP_002528654.1	Code: M; COG: COG0796
YP_002528656.1	Code: C; COG: COG1012
YP_002528657.1	Code: V; COG: COG1132
YP_002528658.1	Code: V; COG: COG1132
YP_002528659.1	Code: ET; COG: COG0834
YP_002528660.1	Code: E; COG: COG0765
YP_002528661.1	Code: E; COG: COG1126
YP_002528666.1	Code: S; COG: COG4399
YP_002528667.1	Code: S; COG: COG3679
YP_002528670.1	Code: TK; COG: COG2197
YP_002528677.1	Code: S; COG: COG4709
YP_002528678.1	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase
YP_002528679.1	Code: Q; COG: COG3527
YP_002528681.1	responsible for recognizing base lesions in the genome and initiating base excision DNA repair
YP_002528682.1	Code: R; COG: COG0561
YP_002528684.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002528685.1	Code: L; COG: COG2963
YP_002528686.1	Code: L; COG: COG2801
YP_002528687.1	activates fatty acids by binding to coenzyme A
YP_002528689.1	Code: P; COG: COG0659
YP_002528692.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins
YP_002528694.1	Code: S; COG: COG2327
YP_002528698.1	Code: M; COG: COG1696
YP_002528699.1	Code: M; COG: COG1696
YP_002528703.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002528706.1	Code: G; COG: COG1363
YP_002528710.1	Code: E; COG: COG3938
YP_002528711.1	catalyzes the formation of L-proline from L-ornithine
YP_002528715.1	Code: E; COG: COG0747
YP_002528716.1	Code: EP; COG: COG0601
YP_002528717.1	Code: EP; COG: COG1173
YP_002528718.1	Code: EP; COG: COG0444
YP_002528719.1	Code: E; COG: COG4608
YP_002528720.1	Code: GEPR; COG: COG0477
YP_002528721.1	Code: T; COG: COG3290
YP_002528722.1	Code: KT; COG: COG4565
YP_002528723.1	Code: S; COG: COG3181
YP_002528730.1	Code: L; COG: COG0338
YP_002528736.1	Code: K; COG: COG0789
YP_002528743.1	unwinds double stranded DNA
YP_002528748.1	Code: R; COG: COG0730
YP_002528754.1	Code: R; COG: COG4188
YP_002528756.1	Code: R; COG: COG5516
YP_002528757.1	Code: T; COG: COG3448
YP_002528760.1	Code: K; COG: COG1846
YP_002528761.1	Code: I; COG: COG1183
YP_002528764.1	similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone
YP_002528765.1	Code: K; COG: COG1309
YP_002528766.1	in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone
YP_002528770.1	Code: KR; COG: COG0454
YP_002528778.1	Code: K; COG: COG1695
YP_002528785.1	Code: S; COG: COG3237
YP_002528786.1	Code: S; COG: COG2261
YP_002528788.1	Code: T; COG: COG1366
YP_002528789.1	binds to sigma-B preventing the formation of an RNA polymerase holoenzyme
YP_002528790.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase
YP_002528791.1	Code: S; COG: COG1633
YP_002528792.1	Code: TK; COG: COG2208
YP_002528793.1	Code: NT; COG: COG1352
YP_002528799.1	Code: S; COG: COG0393
YP_002528802.1	Code: CR; COG: COG0604
YP_002528809.1	Code: L; COG: COG0420
YP_002528811.1	catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates
YP_002528812.1	Code: K; COG: COG1309
YP_002528813.1	Code: GEPR; COG: COG0477
YP_002528814.1	Code: E; COG: COG0346
YP_002528815.1	Code: E; COG: COG0346
YP_002528816.1	Code: S; COG: COG4899
YP_002528824.1	Code: K; COG: COG1954
YP_002528825.1	Code: G; COG: COG0580
YP_002528826.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
YP_002528827.1	Code: C; COG: COG0578
YP_002528829.1	part of sigC operon induced by temperature upshift
YP_002528830.1	part of sigC operon that is induced by temperature upshift
YP_002528831.1	Code: D; COG: COG0772
YP_002528837.1	Code: R; COG: COG3973
YP_002528838.1	cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein
YP_002528840.1	hpr; ScoC; MarR family; protease production regulatory protein
YP_002528841.1	Code: R; COG: COG4980
YP_002528842.1	Code: FGR; COG: COG0537
YP_002528843.1	Code: V; COG: COG1131
YP_002528844.1	Code: U; COG: COG4473
YP_002528849.1	Code: S; COG: COG3402
YP_002528850.1	Code: S; COG: COG3428
YP_002528856.1	Code: S; COG: COG3402
YP_002528857.1	Code: S; COG: COG3428
YP_002528858.1	Code: R; COG: COG2329
YP_002528859.1	Code: M; COG: COG0744
YP_002528860.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_002528861.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002528862.1	catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX
YP_002528864.1	Code: R; COG: COG2374
YP_002528867.1	Code: K; COG: COG1309
YP_002528868.1	Code: S; COG: COG1511
YP_002528869.1	Code: S; COG: COG3860
YP_002528873.1	Code: K; COG: COG2378
YP_002528874.1	Code: K; COG: COG1609
YP_002528875.1	Code: R; COG: COG1234
YP_002528876.1	Code: H; COG: COG0095
YP_002528878.1	activates fatty acids by binding to coenzyme A
YP_002528880.1	similr to Bvg accessory factor
YP_002528894.1	Code: R; COG: COG1073
YP_002528895.1	Code: R; COG: COG1408
YP_002528897.1	Code: R; COG: COG1078
YP_002528899.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002528900.1	Code: S; COG: COG3708
YP_002528902.1	Code: T; COG: COG0642
YP_002528903.1	Code: TK; COG: COG0745
YP_002528908.1	Code: O; COG: COG0501
YP_002528909.1	Code: GER; COG: COG0697
YP_002528913.1	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle
YP_002528914.1	Code: C; COG: COG2224
YP_002528916.1	Code: K; COG: COG1278
YP_002528918.1	Code: K; COG: COG4903
YP_002528920.1	Code: S; COG: COG0398
YP_002528921.1	Code: U; COG: COG0681
YP_002528922.1	Code: L; COG: COG3857
YP_002528923.1	Code: L; COG: COG1074
YP_002528932.1	Code: Q; COG: COG0179
YP_002528933.1	Code: E; COG: COG4992
YP_002528936.1	Code: E; COG: COG0367
YP_002528937.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002528938.1	Code: P; COG: COG0753
YP_002528939.1	Code: P; COG: COG0004
YP_002528941.1	Code: R; COG: COG0457
YP_002528942.1	nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_002528943.1	Code: S; COG: COG2996
YP_002528944.1	Code: M; COG: COG3209
YP_002528950.1	cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein
YP_002528952.1	Code: S; COG: COG1284
YP_002528955.1	Code: R; COG: COG0561
YP_002528957.1	Code: O; COG: COG0542
YP_002528962.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_002528963.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002528964.1	Code: O; COG: COG5504
YP_002528966.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002528968.1	Code: E; COG: COG4166
YP_002528969.1	Code: EP; COG: COG0601
YP_002528970.1	Code: EP; COG: COG1173
YP_002528971.1	Code: EP; COG: COG0444
YP_002528972.1	Code: E; COG: COG4608
YP_002528973.1	Code: V; COG: COG0534
YP_002528974.1	Code: E; COG: COG4166
YP_002528977.1	the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress
YP_002528978.1	Code: P; COG: COG0861
YP_002528979.1	enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence
YP_002528980.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
YP_002528982.1	Code: E; COG: COG1164
YP_002528983.1	Code: Q; COG: COG2761
YP_002528984.1	Code: R; COG: COG2346
YP_002528985.1	Code: S; COG: COG4116
YP_002528987.1	Code: S; COG: COG2357
YP_002528988.1	catalyzes the phosphorylation of NAD to NADP
YP_002528989.1	Code: J; COG: COG0564
YP_002528991.1	asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate
YP_002528992.1	Code: D; COG: COG0772
YP_002528993.1	Code: M; COG: COG0463
YP_002528994.1	Code: QR; COG: COG0500
YP_002529002.1	Code: M; COG: COG1209
YP_002529003.1	Code: M; COG: COG1898
YP_002529004.1	Code: M; COG: COG1088
YP_002529005.1	Code: M; COG: COG1091
YP_002529006.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_002529013.1	Code: L; COG: COG0210
YP_002529014.1	Code: KR; COG: COG0454
YP_002529015.1	similar to 2'-5' RNA ligase
YP_002529016.1	Code: P; COG: COG2382
YP_002529017.1	Code: GER; COG: COG0697
YP_002529020.1	Code: ER; COG: COG0591
YP_002529021.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_002529022.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_002529023.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002529024.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_002529025.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
YP_002529026.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_002529027.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_002529030.1	Code: S; COG: COG5634
YP_002529038.1	Code: R; COG: COG0446
YP_002529039.1	Code: R; COG: COG5628
YP_002529041.1	Code: QR; COG: COG0500
YP_002529045.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
YP_002529046.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_002529047.1	Code: K; COG: COG1476
YP_002529050.1	Code: L; COG: COG0675
YP_002529066.1	Code: L; COG: COG0582
YP_002529068.1	Code: QR; COG: COG0500
YP_002529070.1	Code: M; COG: COG1686
YP_002529071.1	Code: U; COG: COG0681
YP_002529075.1	Code: K; COG: COG1396
YP_002529077.1	Code: S; COG: COG4412
YP_002529078.1	Code: C; COG: COG1012
YP_002529079.1	Code: E; COG: COG3842
YP_002529080.1	Code: E; COG: COG1176
YP_002529081.1	Code: E; COG: COG1177
YP_002529082.1	Code: E; COG: COG0687
YP_002529083.1	Code: I; COG: COG0671
YP_002529084.1	Code: R; COG: COG2409
YP_002529086.1	Code: J; COG: COG0564
YP_002529088.1	Code: S; COG: COG2340
YP_002529089.1	Code: C; COG: COG0247
YP_002529090.1	Code: C; COG: COG0277
YP_002529091.1	Code: KT; COG: COG3835
YP_002529093.1	Code: TK; COG: COG0745
YP_002529094.1	Code: T; COG: COG0642
YP_002529095.1	Code: K; COG: COG2186
YP_002529096.1	Code: C; COG: COG0247
YP_002529097.1	Code: C; COG: COG1139
YP_002529098.1	Code: S; COG: COG1556
YP_002529099.1	Code: NOU; COG: COG1989
YP_002529101.1	Code: P; COG: COG2116
YP_002529102.1	Code: P; COG: COG0861
YP_002529103.1	Code: P; COG: COG0168
YP_002529105.1	Code: I; COG: COG2030
YP_002529109.1	catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis
YP_002529110.1	Code: I; COG: COG3243
YP_002529112.1	Code: P; COG: COG0168
YP_002529115.1	Code: P; COG: COG1840
YP_002529116.1	Code: E; COG: COG3842
YP_002529117.1	Code: P; COG: COG1178
YP_002529118.1	catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate
YP_002529119.1	catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate
YP_002529121.1	Code: KG; COG: COG1349
YP_002529123.1	Code: G; COG: COG0235
YP_002529124.1	Code: R; COG: COG0517
YP_002529125.1	Code: S; COG: COG2861
YP_002529127.1	Code: T; COG: COG0642
YP_002529128.1	Code: K; COG: COG1846
YP_002529129.1	Code: E; COG: COG1164
YP_002529133.1	Code: R; COG: COG0603
YP_002529134.1	Code: H; COG: COG0720
YP_002529135.1	Code: O; COG: COG0602
YP_002529136.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
YP_002529140.1	Code: KR; COG: COG0454
YP_002529143.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
YP_002529146.1	Code: F; COG: COG0208
YP_002529149.1	Code: K; COG: COG1725
YP_002529150.1	Code: V; COG: COG1131
YP_002529152.1	Code: V; COG: COG1131
YP_002529153.1	Code: R; COG: COG1277
YP_002529156.1	Code: K; COG: COG1522
YP_002529157.1	Code: S; COG: COG2128
YP_002529158.1	Code: Q; COG: COG1335
YP_002529160.1	Code: V; COG: COG1619
YP_002529161.1	Code: R; COG: COG2070
YP_002529162.1	Code: M; COG: COG3966
YP_002529163.1	D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid
YP_002529164.1	Code: M; COG: COG1696
YP_002529165.1	transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid
YP_002529168.1	Code: R; COG: COG1473
YP_002529170.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002529177.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
YP_002529178.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002529180.1	Code: K; COG: COG1846
YP_002529182.1	Code: C; COG: COG1301
YP_002529183.1	Code: P; COG: COG0168
YP_002529185.1	Code: S; COG: COG3874
YP_002529189.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002529190.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_002529191.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_002529192.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002529193.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_002529194.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_002529195.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002529196.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_002529197.1	May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YP_002529198.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
YP_002529199.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002529200.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_002529201.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_002529202.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_002529203.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_002529204.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
YP_002529205.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_002529206.1	catalyzes the formation of L-histidinol from L-histidinol phosphate
YP_002529208.1	Code: CHR; COG: COG1052
YP_002529209.1	Code: I; COG: COG1183
YP_002529210.1	Code: M; COG: COG1368
YP_002529212.1	Code: E; COG: COG0019
YP_002529213.1	Code: S; COG: COG5583
YP_002529214.1	Code: EH; COG: COG0175
YP_002529215.1	ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
YP_002529216.1	Code: P; COG: COG0529
YP_002529217.1	Code: P; COG: COG0155
YP_002529219.1	catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1
YP_002529220.1	Code: S; COG: COG2138
YP_002529221.1	catalyzes the formation of siroheme from precorrin-2
YP_002529222.1	Code: R; COG: COG0733
YP_002529225.1	Code: C; COG: COG1301
YP_002529226.1	Code: S; COG: COG2306
YP_002529227.1	Code: C; COG: COG1757
YP_002529229.1	Code: KT; COG: COG1842
YP_002529230.1	Code: S; COG: COG4758
YP_002529231.1	Code: T; COG: COG4585
YP_002529232.1	Code: TK; COG: COG2197
YP_002529234.1	Code: E; COG: COG1114
YP_002529235.1	Code: QR; COG: COG0500
YP_002529240.1	flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine
YP_002529241.1	Code: T; COG: COG0664
YP_002529244.1	Code: P; COG: COG0306
YP_002529245.1	Code: P; COG: COG1392
YP_002529246.1	Code: M; COG: COG0744
YP_002529249.1	Code: S; COG: COG1801
YP_002529251.1	Code: L; COG: COG0582
YP_002529253.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
YP_002529255.1	Code: S; COG: COG2898
YP_002529258.1	Code: P; COG: COG0605
YP_002529259.1	Code: M; COG: COG1686
YP_002529260.1	Code: R; COG: COG2715
YP_002529261.1	Code: S; COG: COG0700
YP_002529262.1	Code: J; COG: COG1187
YP_002529263.1	catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c
YP_002529264.1	Code: O; COG: COG1333
YP_002529265.1	Code: O; COG: COG0755
YP_002529266.1	Code: TK; COG: COG0745
YP_002529267.1	Code: T; COG: COG0642
YP_002529268.1	Code: S; COG: COG2096
YP_002529271.1	Code: S; COG: COG3601
YP_002529272.1	Code: C; COG: COG1141
YP_002529273.1	Code: S; COG: COG4955
YP_002529274.1	Code: L; COG: COG0514
YP_002529275.1	Code: R; COG: COG1266
YP_002529277.1	Code: R; COG: COG1408
YP_002529279.1	enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence
YP_002529280.1	Code: E; COG: COG0334
YP_002529284.1	Code: O; COG: COG0492
YP_002529285.1	Code: EJ; COG: COG0252
YP_002529286.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_002529288.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002529289.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
YP_002529293.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002529294.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002529299.1	Code: L; COG: COG0776
YP_002529300.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_002529302.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_002529303.1	Code: H; COG: COG0142
YP_002529304.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002529305.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002529306.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_002529307.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002529308.1	Code: R; COG: COG0457
YP_002529309.1	Code: S; COG: COG5582
YP_002529311.1	Code: C; COG: COG0723
YP_002529312.1	electron transporter
YP_002529315.1	Code: S; COG: COG4347
YP_002529316.1	Code: S; COG: COG4478
YP_002529318.1	Code: R; COG: COG2738
YP_002529319.1	Code: L; COG: COG1573
YP_002529320.1	Code: S; COG: COG1284
YP_002529321.1	Code: R; COG: COG1694
YP_002529322.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_002529323.1	catalyzes the formation of methylglyoxal from glycerone phosphate
YP_002529324.1	Code: S; COG: COG2120
YP_002529325.1	Code: M; COG: COG0438
YP_002529326.1	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity
YP_002529327.1	Code: H; COG: COG0340
YP_002529328.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_002529329.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_002529330.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_002529331.1	unwinds DNA
YP_002529333.1	Code: S; COG: COG5353
YP_002529334.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_002529335.1	Code: L; COG: COG3935
YP_002529336.1	Code: L; COG: COG0177
YP_002529338.1	Code: M; COG: COG0744
YP_002529339.1	functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC
YP_002529347.1	Code: S; COG: COG4474
YP_002529348.1	Code: D; COG: COG3599
YP_002529349.1	Code: L; COG: COG0116
YP_002529351.1	Code: KL; COG: COG1199
YP_002529352.1	Code: E; COG: COG2317
YP_002529354.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_002529355.1	Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine
YP_002529356.1	Code: F; COG: COG2233
YP_002529357.1	Code: S; COG: COG2311
YP_002529359.1	Code: KR; COG: COG0454
YP_002529361.1	Code: P; COG: COG2897
YP_002529365.1	Code: S; COG: COG3766
YP_002529367.1	Code: L; COG: COG0258
YP_002529371.1	Code: KR; COG: COG0454
YP_002529374.1	Code: GER; COG: COG0697
YP_002529375.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_002529376.1	Code: G; COG: COG2017
YP_002529377.1	Code: S; COG: COG4708
YP_002529381.1	Code: K; COG: COG1278
YP_002529382.1	Code: S; COG: COG3403
YP_002529383.1	Code: E; COG: COG1280
YP_002529385.1	Code: I; COG: COG3000
YP_002529386.1	Code: S; COG: COG3162
YP_002529387.1	Code: R; COG: COG4147
YP_002529388.1	Code: H; COG: COG0161
YP_002529390.1	Code: P; COG: COG0475
YP_002529392.1	Code: R; COG: COG0595
YP_002529394.1	Code: V; COG: COG0534
YP_002529395.1	Code: S; COG: COG2323
YP_002529397.1	Code: S; COG: COG1434
YP_002529399.1	Code: C; COG: COG0778
YP_002529400.1	Code: R; COG: COG0693
YP_002529401.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002529404.1	Code: GEPR; COG: COG0477
YP_002529405.1	Code: K; COG: COG0640
YP_002529409.1	Code: R; COG: COG1923
YP_002529410.1	Code: R; COG: COG1896
YP_002529411.1	Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.
YP_002529412.1	Homolog to MotB, appears to be involved in motility on surfaces and under specific ionic conditions. With MotP (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002529413.1	Code: T; COG: COG0784
YP_002529414.1	Code: NT; COG: COG0643
YP_002529415.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002529418.1	Code: NT; COG: COG1352
YP_002529422.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002529423.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002529424.1	involved in flagellin assembly
YP_002529425.1	Code: NUO; COG: COG1516
YP_002529427.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod
YP_002529428.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_002529429.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_002529430.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_002529431.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002529432.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_002529433.1	involved in type III protein export during flagellum assembly
YP_002529436.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod
YP_002529437.1	the hook connects flagellar basal body to the flagellar filament
YP_002529442.1	Code: N; COG: COG1344
YP_002529443.1	structural flagella protein
YP_002529444.1	Code: M; COG: COG0741
YP_002529445.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002529446.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_002529447.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002529449.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_002529450.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
YP_002529451.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_002529452.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_002529453.1	membrane protein involved in the flagellar export apparatus
YP_002529454.1	positive regulator of class III flagellar genes
YP_002529455.1	makes up the distal portion of the flagellar basal body rod
YP_002529456.1	Code: K; COG: COG1378
YP_002529457.1	Code: E; COG: COG1296
YP_002529458.1	Code: S; COG: COG4392
YP_002529460.1	Code: K; COG: COG1309
YP_002529462.1	Code: Q; COG: COG0412
YP_002529463.1	Code: R; COG: COG2329
YP_002529466.1	Code: M; COG: COG3764
YP_002529467.1	Code: M; COG: COG3764
YP_002529474.1	Code: G; COG: COG3839
YP_002529475.1	Code: P; COG: COG1840
YP_002529484.1	Code: G; COG: COG0406
YP_002529488.1	Code: K; COG: COG1846
YP_002529490.1	Code: E; COG: COG0367
YP_002529491.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002529494.1	Code: P; COG: COG1230
YP_002529497.1	Code: GER; COG: COG0697
YP_002529499.1	Code: C; COG: COG1757
YP_002529500.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_002529503.1	Code: K; COG: COG2771
YP_002529504.1	Code: V; COG: COG0534
YP_002529505.1	Code: E; COG: COG3340
YP_002529508.1	COG0501
YP_002529509.1	Code: OC; COG: COG0526
YP_002529511.1	Code: K; COG: COG1396
YP_002529512.1	Code: E; COG: COG3048
YP_002529518.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in B. thuringiensis this protein is involved in beta-exotoxin I production
YP_002529519.1	Code: TK; COG: COG2197
YP_002529520.1	Code: T; COG: COG4585
YP_002529521.1	Code: V; COG: COG1131
YP_002529523.1	Code: V; COG: COG0842
YP_002529524.1	Code: I; COG: COG1502
YP_002529526.1	Code: TK; COG: COG2197
YP_002529530.1	Catalyzes the phosphorylation of UMP to UDP
YP_002529531.1	Code: C; COG: COG1301
YP_002529532.1	catalyzes the formation of fumarate from aspartate
YP_002529533.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
YP_002529534.1	Code: T; COG: COG0642
YP_002529536.1	Code: KL; COG: COG0553
YP_002529538.1	catalyzes the formation of asparagine from aspartate and ammonia
YP_002529540.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_002529544.1	Code: LR; COG: COG0494
YP_002529550.1	Code: T; COG: COG1966
YP_002529552.1	Code: K; COG: COG1695
YP_002529553.1	Code: GEPR; COG: COG0477
YP_002529554.1	Code: GEPR; COG: COG0477
YP_002529555.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis
YP_002529557.1	Code: R; COG: COG2262
YP_002529558.1	Code: E; COG: COG4166
YP_002529559.1	Code: GEPR; COG: COG0477
YP_002529560.1	Code: E; COG: COG0031
YP_002529561.1	Code: R; COG: COG3981
YP_002529563.1	Code: R; COG: COG2244
YP_002529564.1	Code: R; COG: COG0733
YP_002529565.1	Code: G; COG: COG0726
YP_002529567.1	Code: S; COG: COG2323
YP_002529569.1	Code: O; COG: COG0225
YP_002529570.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002529571.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_002529572.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small subunit
YP_002529573.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002529574.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002529575.1	catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic
YP_002529576.1	Code: M; COG: COG2843
YP_002529577.1	Code: R; COG: COG1811
YP_002529580.1	Code: S; COG: COG3384
YP_002529581.1	Code: I; COG: COG2267
YP_002529583.1	Code: C; COG: COG0427
YP_002529584.1	Code: KR; COG: COG0454
YP_002529586.1	Code: FR; COG: COG0402
YP_002529587.1	Code: R; COG: COG1073
YP_002529589.1	Code: E; COG: COG4166
YP_002529590.1	Code: J; COG: COG1670
YP_002529591.1	Code: TK; COG: COG0745
YP_002529592.1	Code: T; COG: COG0642
YP_002529594.1	Code: P; COG: COG1914
YP_002529595.1	Code: R; COG: COG1054
YP_002529597.1	Code: H; COG: COG1893
YP_002529599.1	Code: E; COG: COG0531
YP_002529606.1	Code: K; COG: COG2390
YP_002529607.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_002529608.1	Code: F; COG: COG1972
YP_002529609.1	Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway
YP_002529610.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002529611.1	Code: O; COG: COG4846
YP_002529612.1	Code: S; COG: COG4224
YP_002529613.1	Code: E; COG: COG0006
YP_002529614.1	Code: S; COG: COG1357
YP_002529616.1	decatenates replicating daughter chromosomes
YP_002533533.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
YP_002529620.1	Code: E; COG: COG1114
YP_002529621.1	Code: E; COG: COG0346
YP_002529622.1	Code: P; COG: COG1276
YP_002529625.1	Code: GER; COG: COG0697
YP_002533534.1	Code: K; COG: COG0583
YP_002529626.1	Code: K; COG: COG1959
YP_002529627.1	Code: Q; COG: COG2761
YP_002529628.1	Code: R; COG: COG3560
YP_002529630.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_002529631.1	Code: R; COG: COG0628
YP_002529632.1	Code: C; COG: COG0039
YP_002529633.1	Code: E; COG: COG1231
YP_002529634.1	Code: R; COG: COG0523
YP_002529636.1	Code: E; COG: COG0411
YP_002533535.1	Code: E; COG: COG0410
YP_002529637.1	Code: E; COG: COG0559
YP_002529638.1	Code: E; COG: COG4177
YP_002529642.1	Code: S; COG: COG0599
YP_002529643.1	Code: K; COG: COG1846
YP_002529644.1	Code: C; COG: COG2141
YP_002529645.1	Code: C; COG: COG1271
YP_002529646.1	Code: C; COG: COG1294
YP_002529647.1	Code: CO; COG: COG4988
YP_002529648.1	Code: CO; COG: COG4987
YP_002529651.1	Code: M; COG: COG0399
YP_002529652.1	Code: R; COG: COG0110
YP_002529655.1	Code: GER; COG: COG0697
YP_002529658.1	Code: M; COG: COG1686
YP_002529659.1	Code: R; COG: COG3560
YP_002529663.1	Code: V; COG: COG1132
YP_002529664.1	Code: TK; COG: COG0745
YP_002529666.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002529667.1	Code: R; COG: COG4122
YP_002529669.1	Code: G; COG: COG0726
YP_002529670.1	Code: S; COG: COG5658
YP_002529671.1	Code: LR; COG: COG0494
YP_002529672.1	Code: R; COG: COG3576
YP_002529674.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_002529675.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_002529676.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_002529679.1	Code: K; COG: COG1316
YP_002529681.1	Code: G; COG: COG0726
YP_002529683.1	Code: S; COG: COG1285
YP_002529684.1	Code: KR; COG: COG0454
YP_002529686.1	Code: GEPR; COG: COG0477
YP_002529687.1	Code: R; COG: COG1279
YP_002529688.1	Code: KE; COG: COG1167
YP_002529690.1	Code: R; COG: COG1752
YP_002529695.1	Code: LR; COG: COG0494
YP_002529696.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_002529697.1	Code: V; COG: COG0577
YP_002529698.1	Code: K; COG: COG2002
YP_002529699.1	Code: O; COG: COG1404
YP_002529700.1	Code: G; COG: COG3839
YP_002529701.1	Code: TQ; COG: COG2508
YP_002529704.1	Code: G; COG: COG1175
YP_002529708.1	Code: KG; COG: COG1940
YP_002529709.1	Code: M; COG: COG2222
YP_002529710.1	Code: G; COG: COG1820
YP_002529711.1	Code: G; COG: COG1105
YP_002529712.1	Code: G; COG: COG3684
YP_002529714.1	catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism
YP_002529715.1	Code: K; COG: COG0640
YP_002529716.1	Code: C; COG: COG0667
YP_002529717.1	Code: G; COG: COG2814
YP_002529721.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002529722.1	Code: NT; COG: COG0840
YP_002529725.1	Code: S; COG: COG3949
YP_002529726.1	Code: P; COG: COG0783
YP_002529730.1	Code: C; COG: COG2141
YP_002529732.1	Code: E; COG: COG1231
YP_002529733.1	Code: J; COG: COG1670
YP_002529734.1	Code: R; COG: COG4989
YP_002529735.1	Code: R; COG: COG0523
YP_002529736.1	Code: KR; COG: COG0454
YP_002529737.1	Code: P; COG: COG0803
YP_002529739.1	Code: MG; COG: COG0702
YP_002529740.1	catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds
YP_002529741.1	Code: L; COG: COG0350
YP_002529743.1	Code: E; COG: COG4166
YP_002529744.1	catalyzes resistance to fosfomycin by the addition of a thiol cofactor
YP_002529746.1	Code: G; COG: COG0406
YP_002529748.1	Code: M; COG: COG5337
YP_002529749.1	Code: F; COG: COG1051
YP_002529750.1	Code: S; COG: COG0586
YP_002529751.1	Code: R; COG: COG2244
YP_002529752.1	Code: P; COG: COG0598
YP_002529753.1	Code: R; COG: COG0701
YP_002529754.1	Code: S; COG: COG3689
YP_002529755.1	Code: I; COG: COG1607
YP_002529756.1	Code: I; COG: COG1502
YP_002529757.1	Code: M; COG: COG5577
YP_002529759.1	Code: MG; COG: COG0702
YP_002529760.1	Code: S; COG: COG2839
YP_002529761.1	Code: R; COG: COG1253
YP_002529763.1	Code: R; COG: COG0517
YP_002529764.1	Code: E; COG: COG1114
YP_002529765.1	Code: R; COG: COG0073
YP_002529768.1	Code: KR; COG: COG0454
YP_002529769.1	Code: M; COG: COG1876
YP_002529770.1	Code: LR; COG: COG0494
YP_002529771.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_002529772.1	Code: GEPR; COG: COG0477
YP_002529773.1	Code: OU; COG: COG1585
YP_002529774.1	Code: O; COG: COG0330
YP_002529775.1	Code: G; COG: COG0406
YP_002529776.1	Code: R; COG: COG0561
YP_002529778.1	Code: M; COG: COG0787
YP_002529782.1	Code: GC; COG: COG1819
YP_002529783.1	Code: S; COG: COG1284
YP_002529784.1	Code: KE; COG: COG1167
YP_002529785.1	Code: KR; COG: COG0454
YP_002529788.1	Code: J; COG: COG1670
YP_002529791.1	Code: KR; COG: COG0454
YP_002529793.1	Code: R; COG: COG0456
YP_002529795.1	Code: R; COG: COG3393
YP_002529796.1	Code: S; COG: COG3874
YP_002529802.1	catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
YP_002529804.1	Code: LKJ; COG: COG0513
YP_002529805.1	Code: E; COG: COG0346
YP_002529807.1	Code: CR; COG: COG0604
YP_002529808.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002529811.1	Code: R; COG: COG0491
YP_002529813.1	Code: O; COG: COG0386
YP_002529814.1	Code: E; COG: COG1305
YP_002529815.1	Code: R; COG: COG1721
YP_002529816.1	Code: R; COG: COG0714
YP_002529819.1	Code: C; COG: COG5013
YP_002529820.1	Code: C; COG: COG1140
YP_002529821.1	Code: C; COG: COG2180
YP_002529822.1	Code: C; COG: COG2181
YP_002529823.1	Code: T; COG: COG0664
YP_002529824.1	Code: H; COG: COG2896
YP_002529825.1	catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways
YP_002529826.1	Code: H; COG: COG0303
YP_002529827.1	Code: H; COG: COG0314
YP_002529828.1	Code: H; COG: COG1977
YP_002529829.1	Code: P; COG: COG2223
YP_002529830.1	Code: KT; COG: COG1983
YP_002529834.1	catalyzes the formation of siroheme from precorrin-2
YP_002529835.1	Code: S; COG: COG2138
YP_002529836.1	this protein contains the C-terminal section of uroporphyrinogen-III methyltransferase fused with uroporphyrinogen-III synthase; studies on Clostridium josui indicate that this protein has uroporphyrinogen-III methylase activity; functions in tetrapyrrole and heme biosynthesis
YP_002529837.1	Code: PR; COG: COG2146
YP_002529838.1	Code: C; COG: COG1251
YP_002529839.1	Code: D; COG: COG2846
YP_002529844.1	Code: Q; COG: COG2162
YP_002529845.1	Code: R; COG: COG1075
YP_002529846.1	Code: S; COG: COG2359
YP_002529850.1	Code: R; COG: COG1418
YP_002529852.1	Code: L; COG: COG3344
YP_002529854.1	Code: S; COG: COG4760
YP_002529856.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_002529857.1	Code: K; COG: COG1309
YP_002529858.1	Code: HC; COG: COG0654
YP_002529862.1	Code: QR; COG: COG0500
YP_002529863.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002529864.1	Code: QR; COG: COG0500
YP_002529866.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)
YP_002529869.1	Code: M; COG: COG0770
YP_002529870.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002529871.1	Code: R; COG: COG0733
YP_002529873.1	Code: S; COG: COG3575
YP_002529875.1	Code: R; COG: COG0546
YP_002529876.1	Code: GE; COG: COG2610
YP_002529877.1	Code: C; COG: COG1454
YP_002529878.1	Code: M; COG: COG1794
YP_002529879.1	Code: S; COG: COG1720
YP_002529880.1	Code: KR; COG: COG0454
YP_002529881.1	Code: E; COG: COG0241
YP_002529883.1	Code: V; COG: COG1131
YP_002529886.1	Code: R; COG: COG0546
YP_002529888.1	Code: R; COG: COG3173
YP_002529889.1	Code: V; COG: COG1680
YP_002529891.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_002529892.1	Code: H; COG: COG0262
YP_002529893.1	Code: M; COG: COG0768
YP_002529894.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
YP_002529895.1	Code: I; COG: COG0204
YP_002529896.1	Code: R; COG: COG1272
YP_002529897.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002529898.1	Code: U; COG: COG0805
YP_002529901.1	Code: S; COG: COG1307
YP_002529902.1	Code: R; COG: COG2220
YP_002529903.1	Code: R; COG: COG1999
YP_002529904.1	Code: O; COG: COG0071
YP_002529905.1	Code: E; COG: COG0367
YP_002529908.1	Code: P; COG: COG0614
YP_002529909.1	catalyzes the transamination of D-amino acids and their alpha-keto acids
YP_002529912.1	Code: Q; COG: COG1335
YP_002529913.1	Code: LR; COG: COG0494
YP_002529914.1	Code: O; COG: COG0071
YP_002529915.1	Code: M; COG: COG0668
YP_002529917.1	Code: TK; COG: COG2197
YP_002529920.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_002529921.1	Code: EP; COG: COG1173
YP_002529923.1	Code: V; COG: COG1680
YP_002529930.1	Code: R; COG: COG0431
YP_002529932.1	Code: S; COG: COG1434
YP_002529933.1	Code: E; COG: COG1125
YP_002529935.1	Code: E; COG: COG0531
YP_002529940.1	remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions
YP_002529941.1	Code: R; COG: COG1253
YP_002529945.1	Code: H; COG: COG0161
YP_002529946.1	Code: I; COG: COG1788
YP_002529947.1	Code: I; COG: COG2057
YP_002529948.1	catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine
YP_002529950.1	Code: KT; COG: COG3829
YP_002529951.1	Code: E; COG: COG1509
YP_002529953.1	Code: S; COG: COG4479
YP_002529958.1	Code: RTKL; COG: COG0515
YP_002529959.1	Code: R; COG: COG4326
YP_002529960.1	Code: I; COG: COG0671
YP_002529961.1	Code: P; COG: COG0053
YP_002529962.1	Code: OC; COG: COG0526
YP_002529972.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress
YP_002529977.1	cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein
YP_002529987.1	Code: S; COG: COG0401
YP_002529988.1	Code: M; COG: COG0744
YP_002529990.1	Code: GEPR; COG: COG0477
YP_002529991.1	Code: S; COG: COG4841
YP_002529992.1	forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration
YP_002529993.1	functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C
YP_002529994.1	Code: G; COG: COG2513
YP_002529996.1	Code: I; COG: COG1960
YP_002529997.1	Code: I; COG: COG2084
YP_002529998.1	Code: C; COG: COG1012
YP_002529999.1	Code: E; COG: COG1280
YP_002530000.1	catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA
YP_002530003.1	Code: L; COG: COG0420
YP_002530004.1	Code: L; COG: COG0419
YP_002530007.1	Code: S; COG: COG4873
YP_002530010.1	Code: GEPR; COG: COG0477
YP_002530011.1	catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin
YP_002530012.1	synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis
YP_002530013.1	Code: Q; COG: COG1021
YP_002530014.1	Code: Q; COG: COG1535
YP_002530016.1	Code: S; COG: COG3251
YP_002530017.1	Code: GEPR; COG: COG0477
YP_002530020.1	Code: L; COG: COG0776
YP_002530022.1	Code: S; COG: COG2318
YP_002530023.1	Code: O; COG: COG1404
YP_002530024.1	Code: E; COG: COG1115
YP_002530030.1	Code: J; COG: COG1187
YP_002530031.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins
YP_002530032.1	Code: V; COG: COG1136
YP_002530035.1	Code: L; COG: COG1943
YP_002530038.1	Code: EP; COG: COG1173
YP_002530039.1	catalyzes the formation of acetyl phosphate from pyruvate
YP_002530041.1	Code: R; COG: COG0491
YP_002530042.1	Code: F; COG: COG1957
YP_002530045.1	Code: KR; COG: COG0454
YP_002530046.1	Code: R; COG: COG0491
YP_002530048.1	Code: R; COG: COG2409
YP_002530052.1	Code: KR; COG: COG0454
YP_002530053.1	Code: GER; COG: COG0697
YP_002530054.1	Code: K; COG: COG1396
YP_002530058.1	catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX
YP_002530060.1	Code: QR; COG: COG0500
YP_002530061.1	Code: J; COG: COG1670
YP_002530063.1	Code: K; COG: COG1278
YP_002530064.1	Code: R; COG: COG1266
YP_002530071.1	Code: K; COG: COG0583
YP_002530072.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002530075.1	Code: K; COG: COG0583
YP_002530076.1	Code: S; COG: COG2258
YP_002530077.1	Code: KR; COG: COG0454
YP_002530078.1	Code: S; COG: COG3506
YP_002530079.1	Code: V; COG: COG1132
YP_002530080.1	Code: V; COG: COG1132
YP_002530081.1	Code: E; COG: COG1280
YP_002530082.1	Code: K; COG: COG1396
YP_002530089.1	Code: Q; COG: COG1233
YP_002530090.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002530093.1	Code: R; COG: COG4122
YP_002530094.1	Code: P; COG: COG3853
YP_002530097.1	Code: S; COG: COG1649
YP_002530098.1	Code: G; COG: COG1440
YP_002530099.1	Code: G; COG: COG1455
YP_002530100.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_002530102.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_002530104.1	catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic
YP_002530105.1	Code: S; COG: COG3339
YP_002530107.1	Code: R; COG: COG0491
YP_002530109.1	Code: LKJ; COG: COG0513
YP_002530114.1	Code: K; COG: COG1309
YP_002530117.1	Code: V; COG: COG1136
YP_002530118.1	Code: QR; COG: COG0500
YP_002530119.1	Code: S; COG: COG3865
YP_002530121.1	Code: GHR; COG: COG3961
YP_002530122.1	Code: K; COG: COG1846
YP_002530123.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002530127.1	Code: E; COG: COG2195
YP_002530130.1	Code: K; COG: COG1595
YP_002530133.1	Code: M; COG: COG0768
YP_002530134.1	Code: V; COG: COG2367
YP_002530135.1	Code: R; COG: COG1408
YP_002530137.1	Code: V; COG: COG1131
YP_002530138.1	Code: V; COG: COG0842
YP_002530139.1	Code: K; COG: COG1309
YP_002530142.1	Code: I; COG: COG1960
YP_002530143.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002530144.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002530145.1	catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA
YP_002530146.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002530147.1	Code: I; COG: COG4799
YP_002530148.1	Code: I; COG: COG0365
YP_002530149.1	Code: J; COG: COG1670
YP_002530151.1	Code: S; COG: COG2318
YP_002530152.1	Code: M; COG: COG1686
YP_002530153.1	Code: T; COG: COG0642
YP_002530154.1	Code: TK; COG: COG0745
YP_002530155.1	Code: H; COG: COG1713
YP_002530157.1	Enables the cleavage of the glycosidic bond in S-adenosylhomocysteine
YP_002530158.1	Code: MG; COG: COG0702
YP_002530162.1	Code: E; COG: COG3227
YP_002530163.1	Protein distantly related to SAM-dependent methyltransferases; Code: S; COG: COG4627
YP_002530165.1	Code: K; COG: COG1695
YP_002530166.1	Code: L; COG: COG4584
YP_002530167.1	Code: L; COG: COG1484
YP_002530168.1	Code: V; COG: COG1680
YP_002530171.1	Code: RTKL; COG: COG0515
YP_002530173.1	Code: QR; COG: COG0500
YP_002530178.1	Code: E; COG: COG1164
YP_002530180.1	Code: KE; COG: COG1167
YP_002530183.1	Code: S; COG: COG2323
YP_002530185.1	Code: QR; COG: COG0500
YP_002530186.1	Code: G; COG: COG3386
YP_002530187.1	Code: J; COG: COG1384
YP_002530188.1	Code: M; COG: COG3773
YP_002530189.1	Code: C; COG: COG2421
YP_002530190.1	Code: TK; COG: COG0745
YP_002530191.1	Code: T; COG: COG0642
YP_002530193.1	Code: R; COG: COG0488
YP_002530194.1	Code: V; COG: COG1136
YP_002530195.1	Code: V; COG: COG0577
YP_002530198.1	Code: R; COG: COG1075
YP_002530199.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_002530200.1	Code: KE; COG: COG1167
YP_002530201.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002530202.1	Code: K; COG: COG0819
YP_002530211.1	Code: Q; COG: COG2124
YP_002530213.1	Code: R; COG: COG0110
YP_002530217.1	Code: R; COG: COG0561
YP_002530219.1	Code: M; COG: COG0768
YP_002530221.1	Code: M; COG: COG1794
YP_002530222.1	Code: S; COG: COG4720
YP_002530224.1	Code: P; COG: COG0619
YP_002530226.1	Code: T; COG: COG0642
YP_002530227.1	Code: RTKL; COG: COG0515
YP_002530228.1	Code: S; COG: COG2320
YP_002530229.1	Code: CR; COG: COG0604
YP_002530230.1	Code: I; COG: COG0671
YP_002530231.1	Code: M; COG: COG0768
YP_002530234.1	Code: IQR; COG: COG1028
YP_002530235.1	Code: GEPR; COG: COG0477
YP_002530236.1	Code: V; COG: COG1680
YP_002530246.1	Code: C; COG: COG0584
YP_002530249.1	Code: KE; COG: COG1167
YP_002530250.1	Code: GER; COG: COG0697
YP_002530251.1	Code: KR; COG: COG0454
YP_002530252.1	Code: S; COG: COG3323
YP_002530253.1	Code: LR; COG: COG0494
YP_002530257.1	Code: GEPR; COG: COG0477
YP_002530258.1	Code: P; COG: COG4300
YP_002530259.1	Code: KR; COG: COG0454
YP_002530261.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002530262.1	Code: LR; COG: COG0494
YP_002530266.1	Code: J; COG: COG0251
YP_002530267.1	Code: S; COG: COG3878
YP_002530272.1	Code: R; COG: COG4667
YP_002530273.1	COG0210
YP_002530274.1	Code: KR; COG: COG0454
YP_002530275.1	similar to Chain D, Yfit From Bacillus Subtilis Is A Probable Metal-Dependent Hydrolase With An Unusual Four-Helix Bundle Topology
YP_002530276.1	Code: J; COG: COG1670
YP_002530278.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002530280.1	Code: L; COG: COG0322
YP_002530285.1	Code: RTKL; COG: COG0515
YP_002530286.1	Code: LR; COG: COG0494
YP_002530287.1	Code: E; COG: COG0665
YP_002530289.1	Code: Q; COG: COG2162
YP_002530290.1	Code: S; COG: COG4815
YP_002530294.1	Code: I; COG: COG0671
YP_002530295.1	Code: G; COG: COG1523
YP_002530298.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance
YP_002530299.1	Code: L; COG: COG3449
YP_002530300.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002530302.1	Code: R; COG: COG0596
YP_002530306.1	Code: S; COG: COG3797
YP_002530307.1	Code: S; COG: COG4129
YP_002530308.1	Code: KR; COG: COG0454
YP_002530314.1	Code: V; COG: COG1680
YP_002530315.1	Code: E; COG: COG3483
YP_002530316.1	Code: R; COG: COG1878
YP_002530317.1	Code: E; COG: COG3844
YP_002530319.1	Code: LR; COG: COG0494
YP_002530324.1	Code: QK; COG: COG3284
YP_002530327.1	Code: KR; COG: COG0454
YP_002530328.1	Code: KG; COG: COG1349
YP_002530331.1	E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002530332.1	Code: C; COG: COG0508
YP_002530333.1	Code: C; COG: COG0022
YP_002530334.1	Code: C; COG: COG1071
YP_002530336.1	Code: IQR; COG: COG1028
YP_002530337.1	Code: S; COG: COG2320
YP_002530340.1	Code: LR; COG: COG0494
YP_002530342.1	COG1435
YP_002530345.1	Code: E; COG: COG4176
YP_002530346.1	Code: E; COG: COG4175
YP_002530347.1	Code: E; COG: COG2113
YP_002530348.1	Code: OU; COG: COG0740
YP_002530349.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002530350.1	Code: C; COG: COG0633
YP_002530351.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_002530352.1	Code: KR; COG: COG0454
YP_002530353.1	Code: GC; COG: COG1819
YP_002530354.1	Code: S; COG: COG1262
YP_002530355.1	In Listeria monocytogenes this protein binds a specific sites on DNA, influencing the topology and transcription; regulates flaA, proU and ompC; is osmoregulated
YP_002530358.1	Code: S; COG: COG2315
YP_002530359.1	Code: KR; COG: COG0454
YP_002530362.1	Code: KR; COG: COG0454
YP_002530364.1	Code: M; COG: COG1247
YP_002530366.1	Code: K; COG: COG1695
YP_002530367.1	Code: S; COG: COG3502
YP_002530368.1	Code: R; COG: COG3973
YP_002530370.1	Code: QR; COG: COG0500
YP_002530371.1	Code: S; COG: COG2105
YP_002530372.1	Code: L; COG: COG0514
YP_002530374.1	COG0548
YP_002530376.1	Code: M; COG: COG3757
YP_002530377.1	Code: M; COG: COG0860
YP_002530380.1	Code: E; COG: COG1164
YP_002530381.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_002530383.1	Code: KR; COG: COG0454
YP_002530385.1	Code: S; COG: COG0599
YP_002530386.1	Code: E; COG: COG1115
YP_002530387.1	Code: C; COG: COG1012
YP_002530388.1	Code: EM; COG: COG0329
YP_002530390.1	Code: E; COG: COG3938
YP_002530392.1	Code: KT; COG: COG3829
YP_002530399.1	Code: S; COG: COG0586
YP_002530400.1	Code: M; COG: COG3966
YP_002530401.1	Code: J; COG: COG1670
YP_002530402.1	Code: E; COG: COG4166
YP_002530403.1	Code: M; COG: COG0791
YP_002530404.1	Code: MR; COG: COG4948
YP_002530406.1	Code: D; COG: COG2919
YP_002530407.1	Code: R; COG: COG0693
YP_002530408.1	Code: F; COG: COG0295
YP_002530413.1	catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue
YP_002530415.1	Code: TK; COG: COG0745
YP_002530417.1	Code: KR; COG: COG0454
YP_002530418.1	Code: R; COG: COG1073
YP_002530419.1	Code: R; COG: COG0546
YP_002530420.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_002530421.1	Code: M; COG: COG1922
YP_002530422.1	Code: E; COG: COG1164
YP_002530423.1	Code: S; COG: COG1307
YP_002530432.1	Code: GEPR; COG: COG0477
YP_002530433.1	Code: M; COG: COG1664
YP_002530434.1	Code: M; COG: COG1664
YP_002530436.1	Code: R; COG: COG4533
YP_002530437.1	Code: GEPR; COG: COG0477
YP_002530442.1	Code: S; COG: COG2261
YP_002530443.1	Code: F; COG: COG1957
YP_002530445.1	Code: QR; COG: COG0500
YP_002530448.1	Code: GEPR; COG: COG0477
YP_002530451.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_002530452.1	Code: I; COG: COG0764
YP_002530453.1	catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A
YP_002530455.1	Code: O; COG: COG4846
YP_002530464.1	Code: R; COG: COG0628
YP_002530467.1	catalyzes the release of sulfite from alkanesulfonates
YP_002530468.1	Code: P; COG: COG0600
YP_002530469.1	Code: P; COG: COG0715
YP_002530470.1	Code: P; COG: COG1116
YP_002530473.1	Code: S; COG: COG2306
YP_002530474.1	Code: LR; COG: COG0494
YP_002530476.1	Code: R; COG: COG0457
YP_002530477.1	Code: H; COG: COG0452
YP_002530478.1	Code: V; COG: COG2746
YP_002530481.1	Code: R; COG: COG0456
YP_002530484.1	Code: KR; COG: COG0454
YP_002530485.1	Code: J; COG: COG1670
YP_002530488.1	Code: G; COG: COG0726
YP_002530490.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
YP_002530491.1	Code: G; COG: COG3414
YP_002530492.1	Code: K; COG: COG3711
YP_002530493.1	Code: P; COG: COG0861
YP_002530494.1	Code: M; COG: COG1368
YP_002530495.1	Code: R; COG: COG0488
YP_002530497.1	Code: R; COG: COG2409
YP_002530498.1	Code: K; COG: COG1309
YP_002530499.1	Code: R; COG: COG4552
YP_002530500.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_002530501.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
YP_002530502.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002530503.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002530504.1	catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
YP_002530512.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
YP_002530513.1	Code: G; COG: COG1879
YP_002530514.1	Code: G; COG: COG1172
YP_002530515.1	Code: G; COG: COG1172
YP_002530516.1	Code: G; COG: COG1129
YP_002530517.1	Code: K; COG: COG2390
YP_002530518.1	Code: G; COG: COG1070
YP_002530519.1	Code: S; COG: COG1917
YP_002530520.1	Code: G; COG: COG1830
YP_002530522.1	Code: R; COG: COG2329
YP_002530523.1	Code: GEPR; COG: COG0477
YP_002530525.1	Code: F; COG: COG1972
YP_002530526.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_002530527.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_002530528.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002530529.1	Code: E; COG: COG4187
YP_002530531.1	Code: E; COG: COG0833
YP_002530532.1	Code: S; COG: COG1690
YP_002530533.1	Code: I; COG: COG3239
YP_002530534.1	Code: S; COG: COG4412
YP_002530535.1	Code: P; COG: COG1785
YP_002530537.1	Code: K; COG: COG3655
YP_002530540.1	Code: S; COG: COG4377
YP_002530542.1	Code: KT; COG: COG3279
YP_002530543.1	Phosphoprylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway
YP_002530544.1	Code: J; COG: COG1670
YP_002530545.1	Code: E; COG: COG0346
YP_002530547.1	Code: K; COG: COG1695
YP_002530548.1	Code: R; COG: COG0714
YP_002530551.1	Code: GEPR; COG: COG0477
YP_002530552.1	Code: E; COG: COG4992
YP_002530553.1	Code: P; COG: COG0753
YP_002530554.1	Code: P; COG: COG0600
YP_002530555.1	Code: P; COG: COG1116
YP_002530559.1	Code: F; COG: COG1001
YP_002530560.1	Code: V; COG: COG1680
YP_002530564.1	Code: R; COG: COG0714
YP_002530565.1	Code: S; COG: COG1359
YP_002530566.1	Code: C; COG: COG0778
YP_002530567.1	Code: K; COG: COG1846
YP_002530568.1	Code: J; COG: COG0480
YP_002530570.1	Code: LR; COG: COG0494
YP_002530572.1	Code: R; COG: COG1277
YP_002530573.1	Code: V; COG: COG1131
YP_002530574.1	Code: K; COG: COG1725
YP_002530576.1	Code: V; COG: COG1136
YP_002530580.1	Code: V; COG: COG1136
YP_002530584.1	Code: V; COG: COG1680
YP_002530586.1	Code: KR; COG: COG0454
YP_002530588.1	Code: LR; COG: COG0494
YP_002530590.1	Code: KE; COG: COG1167
YP_002530591.1	Code: S; COG: COG1671
YP_002530593.1	Code: T; COG: COG0642
YP_002530594.1	Code: TK; COG: COG0745
YP_002530595.1	Code: R; COG: COG0596
YP_002530597.1	phosphorylates nucleosides or dinucleosides to make UMP or CMP as part of the pyrimidine salvage pathway
YP_002530598.1	Code: T; COG: COG0639
YP_002530599.1	Code: R; COG: COG3173
YP_002530601.1	Code: R; COG: COG0730
YP_002530602.1	Code: J; COG: COG1670
YP_002530603.1	Code: E; COG: COG0833
YP_002530605.1	Code: L; COG: COG4335
YP_002530607.1	Code: L; COG: COG4584
YP_002530608.1	Code: L; COG: COG1484
YP_002530609.1	Code: QR; COG: COG0500
YP_002530612.1	Code: LR; COG: COG0494
YP_002530613.1	Code: V; COG: COG3510
YP_002530614.1	Code: U; COG: COG0681
YP_002530615.1	Code: M; COG: COG0768
YP_002530617.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_002530618.1	catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline
YP_002530619.1	Code: S; COG: COG3817
YP_002530620.1	Code: S; COG: COG3819
YP_002530621.1	Code: R; COG: COG1540
YP_002530622.1	Code: E; COG: COG1984
YP_002530623.1	Code: E; COG: COG2049
YP_002530624.1	Code: K; COG: COG1414
YP_002530625.1	Code: U; COG: COG0681
YP_002530626.1	Code: P; COG: COG3142
YP_002530628.1	Code: K; COG: COG0640
YP_002530630.1	Code: GEPR; COG: COG0477
YP_002530631.1	Code: I; COG: COG1960
YP_002530632.1	Code: S; COG: COG1434
YP_002530633.1	Code: J; COG: COG1670
YP_002530635.1	Code: S; COG: COG3314
YP_002530638.1	Code: KR; COG: COG0454
YP_002530640.1	Code: S; COG: COG1633
YP_002530643.1	Code: G; COG: COG0574
YP_002530645.1	Code: R; COG: COG0491
YP_002530646.1	Code: S; COG: COG3336
YP_002530647.1	Code: S; COG: COG4329
YP_002530648.1	Code: M; COG: COG5577
YP_002530650.1	Code: S; COG: COG3403
YP_002530651.1	Code: E; COG: COG1280
YP_002530652.1	Code: E; COG: COG1113
YP_002530658.1	Code: ER; COG: COG1063
YP_002530660.1	catalyzes the formation of fumarate from aspartate
YP_002530661.1	Code: EJ; COG: COG0252
YP_002530662.1	Code: K; COG: COG1396
YP_002530665.1	Code: E; COG: COG0531
YP_002530666.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002530672.1	Code: T; COG: COG0642
YP_002530673.1	catalyzes the formation of glutamate from glutamine
YP_002530674.1	Code: E; COG: COG1115
YP_002530675.1	Code: P; COG: COG0471
YP_002530677.1	Code: V; COG: COG1680
YP_002530678.1	Code: E; COG: COG0665
YP_002530679.1	Code: V; COG: COG0534
YP_002530680.1	Code: E; COG: COG0531
YP_002530681.1	Code: F; COG: COG0737
YP_002530682.1	Code: P; COG: COG0753
YP_002530683.1	Code: P; COG: COG0598
YP_002530689.1	Code: S; COG: COG5294
YP_002530690.1	Code: R; COG: COG0596
YP_002530691.1	Code: T; COG: COG3476
YP_002530692.1	Code: L; COG: COG0415
YP_002530695.1	Code: P; COG: COG0288
YP_002530696.1	Code: S; COG: COG3002
YP_002530697.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002530698.1	Code: S; COG: COG5609
YP_002530702.1	Code: KR; COG: COG0454
YP_002530703.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_002530705.1	Code: V; COG: COG1136
YP_002530706.1	Code: V; COG: COG0577
YP_002530708.1	Code: TK; COG: COG2197
YP_002530709.1	Code: R; COG: COG0693
YP_002530713.1	Code: S; COG: COG3347
YP_002530714.1	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
YP_002530715.1	Code: G; COG: COG1070
YP_002530716.1	Code: G; COG: COG0235
YP_002530717.1	Code: G; COG: COG1879
YP_002530718.1	Code: G; COG: COG1172
YP_002530720.1	Code: G; COG: COG4154
YP_002530721.1	Code: K; COG: COG1609
YP_002530724.1	catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates
YP_002530725.1	Code: P; COG: COG0798
YP_002530726.1	Code: E; COG: COG0346
YP_002530727.1	Code: K; COG: COG0640
YP_002530729.1	Code: H; COG: COG0262
YP_002530732.1	Code: V; COG: COG1136
YP_002530739.1	Code: G; COG: COG2814
YP_002530740.1	Code: K; COG: COG1309
YP_002530741.1	Code: IQR; COG: COG1028
YP_002530742.1	Code: K; COG: COG1522
YP_002530743.1	Code: R; COG: COG1473
YP_002530745.1	Code: E; COG: COG0346
YP_002530750.1	Code: K; COG: COG1846
YP_002530752.1	Code: GEPR; COG: COG0477
YP_002530760.1	catalyzes the formation of pyruvate from D-cysteine
YP_002530762.1	Code: E; COG: COG2309
YP_002530766.1	Code: Q; COG: COG3315
YP_002530769.1	Code: V; COG: COG1136
YP_002530770.1	Code: V; COG: COG0577
YP_002530772.1	Code: GEPR; COG: COG0477
YP_002530774.1	Code: T; COG: COG0642
YP_002530775.1	Code: TK; COG: COG0745
YP_002530776.1	Code: S; COG: COG2364
YP_002530777.1	Code: K; COG: COG1846
YP_002530778.1	Code: KR; COG: COG0454
YP_002530779.1	Code: K; COG: COG2808
YP_002530780.1	Code: S; COG: COG1284
YP_002530781.1	Code: GEPR; COG: COG0477
YP_002530782.1	Code: S; COG: COG1556
YP_002530783.1	Code: C; COG: COG1139
YP_002530784.1	Code: C; COG: COG0247
YP_002530785.1	Code: K; COG: COG0583
YP_002530787.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002530788.1	Code: V; COG: COG1619
YP_002530790.1	Code: S; COG: COG4198
YP_002530791.1	Code: HE; COG: COG0111
YP_002530792.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_002530794.1	Code: G; COG: COG0662
YP_002530795.1	Code: K; COG: COG2207
YP_002530797.1	Code: R; COG: COG2366
YP_002530806.1	Code: E; COG: COG0346
YP_002530809.1	Code: GEPR; COG: COG0477
YP_002530812.1	Code: K; COG: COG1846
YP_002530813.1	Code: GEPR; COG: COG0477
YP_002530814.1	Code: V; COG: COG1680
YP_002530817.1	Code: V; COG: COG1131
YP_002530818.1	COG1502
YP_002530819.1	COG0640
YP_002530820.1	Code: P; COG: COG2076
YP_002530821.1	Code: K; COG: COG1309
YP_002530823.1	Code: I; COG: COG2031
YP_002530825.1	Code: R; COG: COG2249
YP_002530826.1	Code: S; COG: COG4715
YP_002530829.1	COG2271
YP_002530835.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_002530836.1	Code: S; COG: COG1288
YP_002530844.1	Code: LR; COG: COG0494
YP_002530846.1	Code: S; COG: COG2606
YP_002530847.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002530851.1	Code: K; COG: COG1733
YP_002530852.1	Code: C; COG: COG0778
YP_002530853.1	Code: S; COG: COG3906
YP_002530854.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002530856.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002530858.1	Code: V; COG: COG1131
YP_002530861.1	Code: K; COG: COG1476
YP_002530863.1	Code: R; COG: COG1011
YP_002530864.1	Code: T; COG: COG2365
YP_002530867.1	Code: LR; COG: COG0494
YP_002530868.1	Code: E; COG: COG0346
YP_002530870.1	Code: R; COG: COG0110
YP_002530871.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002530873.1	Code: R; COG: COG0628
YP_002530874.1	Code: S; COG: COG2261
YP_002530875.1	Code: KR; COG: COG0454
YP_002530878.1	Code: QR; COG: COG0500
YP_002530883.1	Code: S; COG: COG4843
YP_002530885.1	Code: R; COG: COG1253
YP_002530886.1	Code: K; COG: COG0789
YP_002530888.1	Code: MJ; COG: COG1208
YP_002530889.1	Code: MG; COG: COG0451
YP_002530890.1	Code: QR; COG: COG0500
YP_002530897.1	Code: S; COG: COG1357
YP_002530898.1	Code: S; COG: COG3813
YP_002530899.1	Code: G; COG: COG2706
YP_002530900.1	Code: G; COG: COG1070
YP_002530901.1	Code: GE; COG: COG2610
YP_002530902.1	similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity
YP_002530903.1	similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate
YP_002530904.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002530905.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002530907.1	Code: C; COG: COG2141
YP_002530909.1	Code: CR; COG: COG0604
YP_002530910.1	Code: IQR; COG: COG1028
YP_002530911.1	Code: R; COG: COG3560
YP_002530913.1	Code: R; COG: COG0656
YP_002530914.1	Code: G; COG: COG2814
YP_002530916.1	Code: S; COG: COG4702
YP_002530918.1	Code: E; COG: COG0814
YP_002530920.1	Code: K; COG: COG1959
YP_002530923.1	the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress
YP_002530924.1	Code: K; COG: COG1733
YP_002530925.1	Code: K; COG: COG2188
YP_002530926.1	Code: R; COG: COG0673
YP_002530927.1	Code: M; COG: COG2230
YP_002530928.1	Code: K; COG: COG1733
YP_002530929.1	Code: K; COG: COG1733
YP_002530930.1	Code: C; COG: COG0667
YP_002530937.1	Code: R; COG: COG0384
YP_002530939.1	Code: IQR; COG: COG1028
YP_002530940.1	Code: J; COG: COG1670
YP_002530941.1	Code: J; COG: COG1670
YP_002530942.1	Code: IQ; COG: COG0318
YP_002530943.1	Code: R; COG: COG2249
YP_002530944.1	Code: K; COG: COG1733
YP_002530946.1	Code: K; COG: COG0640
YP_002530949.1	Heat shock-induced
YP_002530950.1	Code: M; COG: COG0463
YP_002530951.1	Code: S; COG: COG0393
YP_002530953.1	Code: K; COG: COG1309
YP_002530957.1	Code: V; COG: COG0842
YP_002530958.1	Code: V; COG: COG1131
YP_002530959.1	Code: S; COG: COG4817
YP_002530960.1	Code: K; COG: COG1695
YP_002530961.1	catalyzes the reduction of hydroxylamine to ammonia and water
YP_002530964.1	Code: R; COG: COG1694
YP_002530970.1	Code: P; COG: COG2072
YP_002530971.1	Code: T; COG: COG0639
YP_002530972.1	Code: T; COG: COG0664
YP_002530976.1	Code: R; COG: COG0491
YP_002530977.1	Code: CR; COG: COG0604
YP_002530978.1	Code: E; COG: COG1113
YP_002530985.1	Code: GEPR; COG: COG0477
YP_002530989.1	Code: S; COG: COG2120
YP_002530991.1	Code: P; COG: COG1055
YP_002530994.1	Code: P; COG: COG0614
YP_002530995.1	Code: P; COG: COG0609
YP_002530996.1	Code: P; COG: COG0609
YP_002530997.1	Code: S; COG: COG3739
YP_002531000.1	Code: S; COG: COG2318
YP_002531001.1	Code: J; COG: COG1670
YP_002531004.1	Code: K; COG: COG0583
YP_002531005.1	Code: CR; COG: COG0604
YP_002531006.1	Code: J; COG: COG2890
YP_002531007.1	Code: G; COG: COG0406
YP_002531008.1	Code: R; COG: COG3153
YP_002531009.1	Code: L; COG: COG1193
YP_002531010.1	Code: Q; COG: COG2162
YP_002531011.1	Code: E; COG: COG1164
YP_002531012.1	Code: V; COG: COG1680
YP_002531013.1	Code: GEPR; COG: COG0477
YP_002531014.1	Code: K; COG: COG0583
YP_002531018.1	Code: L; COG: COG1943
YP_002531019.1	Code: K; COG: COG0640
YP_002531020.1	Code: CR; COG: COG0604
YP_002531021.1	Code: S; COG: COG0397
YP_002531025.1	Code: K; COG: COG2808
YP_002531026.1	Code: S; COG: COG2320
YP_002531027.1	Code: R; COG: COG0385
YP_002531028.1	Code: C; COG: COG0277
YP_002531034.1	Code: S; COG: COG1285
YP_002531035.1	Code: R; COG: COG3981
YP_002531037.1	Code: R; COG: COG2514
YP_002531038.1	Code: ET; COG: COG0834
YP_002531039.1	Code: E; COG: COG1126
YP_002531040.1	similar to VC0009; Code: E; COG: COG0765
YP_002531041.1	Code: V; COG: COG2720
YP_002531046.1	has 3'-5' exonuclease activity
YP_002531047.1	Code: K; COG: COG1278
YP_002531049.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002531050.1	Code: S; COG: COG1584
YP_002531055.1	Code: S; COG: COG4043
YP_002531056.1	Code: R; COG: COG0110
YP_002531058.1	Code: IQR; COG: COG1028
YP_002531060.1	catalyzes the formation of arginine and fumarate from arginosuccinate
YP_002531062.1	Code: F; COG: COG1957
YP_002531063.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
YP_002531064.1	Code: S; COG: COG3924
YP_002531065.1	Code: C; COG: COG1012
YP_002531066.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002531068.1	Code: I; COG: COG1657
YP_002531069.1	Code: S; COG: COG1963
YP_002531070.1	Code: R; COG: COG2962
YP_002531071.1	Code: S; COG: COG3326
YP_002531074.1	Code: D; COG: COG0489
YP_002531075.1	Code: H; COG: COG1977
YP_002531076.1	Code: H; COG: COG0314
YP_002531077.1	Code: H; COG: COG0303
YP_002531078.1	catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways
YP_002531079.1	Code: P; COG: COG2116
YP_002531080.1	Code: H; COG: COG2896
YP_002531081.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
YP_002531082.1	Code: S; COG: COG5609
YP_002531083.1	Code: S; COG: COG2427
YP_002531084.1	Code: R; COG: COG3383
YP_002531094.1	Code: QR; COG: COG0500
YP_002531095.1	Code: E; COG: COG4166
YP_002531096.1	Code: E; COG: COG4166
YP_002531097.1	Code: E; COG: COG4166
YP_002531098.1	involved in the transport of C4-dicarboxylates across the membrane
YP_002531099.1	Code: K; COG: COG1316
YP_002531104.1	Code: V; COG: COG1131
YP_002531106.1	Code: R; COG: COG0673
YP_002531107.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002531108.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002531109.1	Code: R; COG: COG1832
YP_002531110.1	Code: O; COG: COG0265
YP_002531111.1	Code: TK; COG: COG0745
YP_002531112.1	Code: O; COG: COG0602
YP_002531113.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_002531115.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_002531116.1	Code: S; COG: COG4841
YP_002531117.1	Code: R; COG: COG0824
YP_002531118.1	Code: R; COG: COG3858
YP_002531120.1	SASP N; found in forespore compartment
YP_002531122.1	3'-5' exonuclease of DNA polymerase III
YP_002531123.1	Code: OC; COG: COG0526
YP_002531125.1	Catalyzes the conversion of citrate to isocitrate
YP_002531126.1	SASP O; found in forespore compartment
YP_002531127.1	Code: G; COG: COG0726
YP_002531129.1	SASP P; found in forespore compartment
YP_002531136.1	Code: R; COG: COG2872
YP_002531137.1	Code: F; COG: COG1051
YP_002531141.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002531142.1	activates fatty acids by binding to coenzyme A
YP_002531143.1	Code: R; COG: COG1268
YP_002531144.1	Code: IQ; COG: COG0318
YP_002531146.1	Code: V; COG: COG1131
YP_002531150.1	Code: S; COG: COG3237
YP_002531152.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002531156.1	Code: S; COG: COG1284
YP_002531157.1	Code: E; COG: COG0346
YP_002531159.1	Code: R; COG: COG0400
YP_002531160.1	Code: E; COG: COG0346
YP_002531161.1	Code: ER; COG: COG0591
YP_002531162.1	Code: O; COG: COG4846
YP_002531163.1	Code: E; COG: COG0069
YP_002531164.1	Code: C; COG: COG1902
YP_002531165.1	Code: K; COG: COG1329
YP_002531166.1	catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate
YP_002531167.1	catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway
YP_002531168.1	catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism
YP_002531169.1	catalyzes the degradation of histidine to urocanate and ammmonia
YP_002531170.1	regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure
YP_002531173.1	similar to Bacillus subtilus 24.1 kDa protein, corresponds to Swiss-Prot Accession Number P37530
YP_002531181.1	Code: O; COG: COG4846
YP_002531182.1	Code: O; COG: COG0785
YP_002531183.1	Code: GER; COG: COG0697
YP_002531184.1	Code: R; COG: COG1473
YP_002531185.1	Code: R; COG: COG1277
YP_002531186.1	Code: V; COG: COG1131
YP_002531188.1	Code: K; COG: COG0583
YP_002531189.1	increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB
YP_002531190.1	Code: M; COG: COG1346
YP_002531199.1	Code: V; COG: COG1132
YP_002531200.1	Code: V; COG: COG1132
YP_002531201.1	Code: S; COG: COG3763
YP_002531203.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002531204.1	Code: P; COG: COG3639
YP_002531205.1	Code: P; COG: COG3639
YP_002531206.1	Code: P; COG: COG3638
YP_002531207.1	Code: P; COG: COG3221
YP_002531208.1	Code: F; COG: COG0737
YP_002531209.1	Code: S; COG: COG4224
YP_002531210.1	Code: L; COG: COG1961
YP_002531211.1	Represses a number of genes involved in the response to DNA damage
YP_002531213.1	Code: S; COG: COG4709
YP_002531214.1	Code: K; COG: COG1695
YP_002531215.1	Code: E; COG: COG0174
YP_002531216.1	Code: K; COG: COG0789
YP_002531217.1	Code: P; COG: COG4100
YP_002531218.1	Code: R; COG: COG2262
YP_002531219.1	Code: S; COG: COG2860
YP_002531221.1	ATPase family associated with various cellular activities; Code: O; COG: COG0464
YP_002531222.1	Code: L; COG: COG0582
YP_002531225.1	Stimulates the elongation of poly(A) tails
YP_002531226.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002531230.1	Code: G; COG: COG1105
YP_002531231.1	Code: KG; COG: COG1349
YP_002531232.1	Code: C; COG: COG1979
YP_002531233.1	Code: S; COG: COG2322
YP_002531236.1	Code: E; COG: COG1113
YP_002531237.1	Code: G; COG: COG3469
YP_002531238.1	Code: R; COG: COG1408
YP_002531239.1	Code: P; COG: COG2116
YP_002531240.1	Code: L; COG: COG0776
YP_002531241.1	Code: KR; COG: COG0454
YP_002531242.1	Code: P; COG: COG2217
YP_002531243.1	Code: P; COG: COG2608
YP_002531244.1	Code: S; COG: COG1937
YP_002531246.1	Code: R; COG: COG2819
YP_002531247.1	Code: PH; COG: COG1120
YP_002531248.1	Code: P; COG: COG0609
YP_002531249.1	Code: P; COG: COG0609
YP_002531250.1	Code: P; COG: COG0614
YP_002531251.1	Code: F; COG: COG2169
YP_002531252.1	Code: L; COG: COG0350
YP_002531253.1	Code: L; COG: COG0122
YP_002531254.1	catalyzes the release of the N-terminal amino acid from a tripeptide
YP_002531255.1	Code: S; COG: COG2364
YP_002531261.1	Code: KE; COG: COG1167
YP_002531267.1	Code: M; COG: COG1368
YP_002531270.1	Code: M; COG: COG3049
YP_002531271.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_002531272.1	This protein performs the mismatch recognition step during the DNA repair process
YP_002531274.1	Code: S; COG: COG4550
YP_002531275.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_002531276.1	catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin
YP_002531277.1	Code: C; COG: COG0674
YP_002531278.1	Code: E; COG: COG2355
YP_002531279.1	Code: S; COG: COG2359
YP_002531280.1	Code: S; COG: COG1692
YP_002531281.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_002531285.1	Code: I; COG: COG0558
YP_002531286.1	Code: S; COG: COG1426
YP_002531289.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002531290.1	Code: R; COG: COG0612
YP_002531291.1	Code: R; COG: COG0612
YP_002531292.1	Code: R; COG: COG1079
YP_002531293.1	Code: R; COG: COG4603
YP_002531294.1	Code: R; COG: COG3845
YP_002531295.1	Code: R; COG: COG1744
YP_002531296.1	Code: K; COG: COG2188
YP_002531297.1	Code: D; COG: COG1674
YP_002531299.1	Code: OU; COG: COG0740
YP_002531300.1	Code: R; COG: COG0595
YP_002531301.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002531302.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive
YP_002531303.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002531304.1	involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme
YP_002531305.1	catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance
YP_002531306.1	Code: S; COG: COG1873
YP_002531307.1	Code: R; COG: COG0612
YP_002531308.1	Code: G; COG: COG0726
YP_002531309.1	Code: J; COG: COG1185
YP_002531310.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_002531311.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_002531312.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_002531313.1	Code: S; COG: COG1550
YP_002531314.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002531315.1	Code: J; COG: COG1358
YP_002531316.1	Code: K; COG: COG2740
YP_002531317.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002531318.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_002531319.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
YP_002531321.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002531322.1	Code: M; COG: COG0750
YP_002531323.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_002531324.1	Code: I; COG: COG0575
YP_002531325.1	Code: I; COG: COG0020
YP_002531326.1	Code: J; COG: COG0233
YP_002531327.1	Code: F; COG: COG0528
YP_002531328.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002531329.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002531330.1	CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
YP_002531331.1	heat shock protein involved in degradation of misfolded proteins
YP_002531332.1	heat shock protein involved in degradation of misfolded proteins
YP_002531333.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002531334.1	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
YP_002531335.1	Code: L; COG: COG0550
YP_002531336.1	Code: LU; COG: COG0758
YP_002531337.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_002531338.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_002531339.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002531340.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_002531341.1	Code: U; COG: COG0681
YP_002531342.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002531343.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002531344.1	Essential for efficient processing of 16S rRNA
YP_002531345.1	Code: R; COG: COG1837
YP_002531346.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002531347.1	Code: U; COG: COG0541
YP_002531348.1	Code: S; COG: COG2739
YP_002531349.1	Code: U; COG: COG0552
YP_002531350.1	Code: D; COG: COG1196
YP_002531351.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002531352.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002531353.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002531354.1	Code: I; COG: COG0331
YP_002531355.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_002531356.1	negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria
YP_002531357.1	catalyzes branch migration in Holliday junction intermediates
YP_002531358.1	Code: R; COG: COG1461
YP_002531359.1	Code: S; COG: COG1302
YP_002531360.1	required for 70S ribosome assembly
YP_002531361.1	Code: H; COG: COG1564
YP_002531362.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_002531363.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002531365.1	Code: T; COG: COG0631
YP_002531366.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_002531367.1	Code: J; COG: COG0144
YP_002531368.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_002531369.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002531370.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_002531371.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_002531372.1	Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_002531373.1	Essential for recycling GMP and indirectly, cGMP
YP_002531374.1	Code: S; COG: COG2052
YP_002531375.1	Code: S; COG: COG1561
YP_002531376.1	Code: P; COG: COG0474
YP_002531377.1	Code: K; COG: COG1293
YP_002531378.1	Code: E; COG: COG0006
YP_002531384.1	Code: R; COG: COG1011
YP_002531385.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002531386.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_002531387.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits
YP_002531388.1	responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+)
YP_002531389.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_002531390.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_002531391.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_002531392.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_002531393.1	Code: F; COG: COG2233
YP_002531394.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_002531395.1	Code: J; COG: COG0564
YP_002531396.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002531398.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_002531399.1	Code: D; COG: COG3599
YP_002531400.1	Code: S; COG: COG2302
YP_002531401.1	Code: S; COG: COG0762
YP_002531402.1	Code: S; COG: COG1799
YP_002531403.1	Code: R; COG: COG0325
YP_002531404.1	Code: S; COG: COG1496
YP_002531405.1	Code: S; COG: COG1873
YP_002531406.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin
YP_002531407.1	sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation
YP_002531409.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002531410.1	Code: D; COG: COG0849
YP_002531411.1	Code: M; COG: COG1589
YP_002531412.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002531413.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002531414.1	Code: D; COG: COG0772
YP_002531415.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_002531416.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002531417.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_002531418.1	Code: M; COG: COG0768
YP_002531419.1	Code: M; COG: COG0768
YP_002531420.1	Code: D; COG: COG4839
YP_002531421.1	Code: M; COG: COG0275
YP_002531422.1	Code: S; COG: COG4365
YP_002531423.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_002531425.1	Code: KR; COG: COG0454
YP_002531427.1	Code: R; COG: COG1399
YP_002531428.1	Code: R; COG: COG1323
YP_002531429.1	Code: T; COG: COG3480
YP_002531430.1	Code: R; COG: COG1752
YP_002531432.1	Code: S; COG: COG3314
YP_002531433.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002531434.1	Code: L; COG: COG0742
YP_002531438.1	Code: S; COG: COG3679
YP_002531439.1	Code: G; COG: COG0406
YP_002531442.1	Code: S; COG: COG2340
YP_002531444.1	formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate
YP_002531445.1	Code: S; COG: COG3336
YP_002531446.1	Code: C; COG: COG3125
YP_002531447.1	Code: C; COG: COG1845
YP_002531448.1	Code: C; COG: COG0843
YP_002531449.1	Code: C; COG: COG1622
YP_002531450.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_002531451.1	Code: O; COG: COG1612
YP_002531452.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_002531453.1	Code: D; COG: COG0772
YP_002531454.1	depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein
YP_002531456.1	Code: T; COG: COG1875
YP_002531458.1	Code: S; COG: COG4896
YP_002531460.1	COG1173
YP_002531461.1	Code: T; COG: COG1217
YP_002531466.1	Code: S; COG: COG4493
YP_002531467.1	Code: S; COG: COG4476
YP_002531468.1	Code: E; COG: COG1982
YP_002531469.1	involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links
YP_002531475.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002531476.1	Code: C; COG: COG0508
YP_002531477.1	Code: C; COG: COG0022
YP_002531478.1	Code: C; COG: COG1071
YP_002531480.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002531481.1	Code: R; COG: COG0561
YP_002531482.1	Code: S; COG: COG5503
YP_002531483.1	Code: R; COG: COG0595
YP_002531484.1	Code: P; COG: COG0569
YP_002531486.1	Code: R; COG: COG1473
YP_002531487.1	Code: E; COG: COG2171
YP_002531488.1	Code: K; COG: COG0583
YP_002531489.1	Code: R; COG: COG0517
YP_002531491.1	Code: S; COG: COG1978
YP_002531492.1	Code: O; COG: COG0695
YP_002531495.1	Code: IQR; COG: COG1028
YP_002531496.1	Code: R; COG: COG1408
YP_002531499.1	Code: FP; COG: COG0248
YP_002531505.1	Code: GEPR; COG: COG0477
YP_002531507.1	COG1695
YP_002531508.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002531513.1	Code: T; COG: COG0642
YP_002531515.1	Code: E; COG: COG0436
YP_002531516.1	Code: K; COG: COG1609
YP_002531517.1	Code: G; COG: COG3833
YP_002531518.1	Code: G; COG: COG1175
YP_002531519.1	Code: G; COG: COG2182
YP_002531520.1	Code: G; COG: COG0366
YP_002531521.1	Code: G; COG: COG0366
YP_002531522.1	Code: G; COG: COG3839
YP_002531529.1	Code: R; COG: COG3910
YP_002531530.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002531531.1	Code: LR; COG: COG0494
YP_002531537.1	catalyzes the formation of acetoacetate from 3-hydroxybutyrate
YP_002531539.1	isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway
YP_002531540.1	phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway
YP_002531541.1	Code: R; COG: COG0388
YP_002531542.1	produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however
YP_002531543.1	converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage
YP_002531544.1	converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage
YP_002531545.1	converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage
YP_002531546.1	Code: S; COG: COG1791
YP_002531549.1	Code: I; COG: COG2084
YP_002531550.1	Code: V; COG: COG1680
YP_002531552.1	Code: C; COG: COG0778
YP_002531555.1	Code: G; COG: COG1080
YP_002531556.1	Code: G; COG: COG1925
YP_002531557.1	Code: G; COG: COG1263
YP_002531558.1	Code: K; COG: COG3711
YP_002531560.1	Code: K; COG: COG2188
YP_002531561.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
YP_002531562.1	Code: G; COG: COG1820
YP_002531563.1	Code: R; COG: COG2333
YP_002531564.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer
YP_002531565.1	functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB
YP_002531567.1	Code: S; COG: COG1547
YP_002531569.1	Code: O; COG: COG0652
YP_002531570.1	Code: S; COG: COG4086
YP_002531579.1	Code: R; COG: COG0733
YP_002531580.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.
YP_002531581.1	binds to sigma F preventing its association with RNA polymerase during sporulation
YP_002531582.1	Code: T; COG: COG1366
YP_002531583.1	Code: M; COG: COG1686
YP_002531584.1	Code: K; COG: COG1725
YP_002531585.1	Code: V; COG: COG1131
YP_002531589.1	Code: K; COG: COG1846
YP_002531590.1	Code: S; COG: COG2968
YP_002531591.1	Code: R; COG: COG2252
YP_002531592.1	Code: P; COG: COG0598
YP_002531593.1	Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway
YP_002531594.1	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation
YP_002531595.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_002531597.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002531599.1	Code: P; COG: COG0735
YP_002531600.1	Code: S; COG: COG1300
YP_002531602.1	Code: LR; COG: COG0494
YP_002531604.1	Code: C; COG: COG0667
YP_002531605.1	Code: R; COG: COG0656
YP_002531606.1	Code: S; COG: COG2320
YP_002531608.1	Code: F; COG: COG0737
YP_002531610.1	Code: R; COG: COG0596
YP_002531611.1	Code: R; COG: COG2056
YP_002531612.1	Code: K; COG: COG1609
YP_002531613.1	Code: KR; COG: COG0454
YP_002531614.1	Code: R; COG: COG1073
YP_002531617.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_002531618.1	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate
YP_002531619.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002531621.1	catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine
YP_002531622.1	Code: QR; COG: COG0500
YP_002531624.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_002531625.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002531626.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_002531629.1	Code: C; COG: COG1757
YP_002531630.1	in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate
YP_002531635.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_002531636.1	Code: E; COG: COG4992
YP_002531637.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_002531638.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_002531639.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_002531641.1	Code: R; COG: COG0300
YP_002531642.1	Code: R; COG: COG0491
YP_002531643.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002531644.1	Code: E; COG: COG1760
YP_002531645.1	Code: E; COG: COG1760
YP_002531647.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_002531650.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002531651.1	Code: E; COG: COG2195
YP_002531652.1	Code: J; COG: COG1670
YP_002531655.1	Code: S; COG: COG1376
YP_002531656.1	Code: S; COG: COG4129
YP_002531657.1	Code: E; COG: COG1126
YP_002531658.1	Code: E; COG: COG0765
YP_002531659.1	Code: ET; COG: COG0834
YP_002531661.1	Code: LR; COG: COG0494
YP_002531663.1	Code: D; COG: COG0772
YP_002531664.1	Code: C; COG: COG0508
YP_002531665.1	Code: C; COG: COG0022
YP_002531666.1	Code: C; COG: COG1071
YP_002531667.1	E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002531668.1	catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate
YP_002531669.1	Code: E; COG: COG0334
YP_002531670.1	catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate
YP_002531671.1	Code: KT; COG: COG3829
YP_002531673.1	Code: C; COG: COG0584
YP_002531676.1	Code: M; COG: COG0750
YP_002531677.1	Code: L; COG: COG0497
YP_002531678.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_002531679.1	Code: J; COG: COG1189
YP_002531680.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_002531681.1	Code: H; COG: COG0142
YP_002531682.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_002531683.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_002531684.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_002531685.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002531686.1	Code: S; COG: COG1302
YP_002531687.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002531688.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002531696.1	necessary for complete engulfment of forespore
YP_002531697.1	Code: S; COG: COG3854
YP_002531701.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_002531702.1	Code: E; COG: COG0006
YP_002531703.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_002531705.1	Code: R; COG: COG3872
YP_002531708.1	involved in manganese homeostasis; activates the transcription of the mntABCD operon
YP_002531709.1	Code: L; COG: COG1533
YP_002531712.1	Code: H; COG: COG0095
YP_002531713.1	Code: P; COG: COG0607
YP_002531714.1	Code: K; COG: COG1609
YP_002531715.1	Code: K; COG: COG1309
YP_002531716.1	Code: P; COG: COG2076
YP_002531717.1	Code: P; COG: COG2076
YP_002531723.1	Code: V; COG: COG1131
YP_002531724.1	Code: K; COG: COG1725
YP_002531727.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
YP_002531728.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein
YP_002531729.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002531730.1	Code: KL; COG: COG0553
YP_002531736.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002531741.1	Code: NU; COG: COG2165
YP_002531742.1	Code: U; COG: COG4537
YP_002531743.1	Code: NU; COG: COG1459
YP_002531744.1	Code: NU; COG: COG2804
YP_002531747.1	Code: R; COG: COG1823
YP_002531754.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002531755.1	Code: E; COG: COG1410
YP_002531756.1	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions
YP_002531758.1	catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity
YP_002531759.1	catalyzes the formation of L-homocysteine from cystathionine
YP_002531760.1	Code: Q; COG: COG1335
YP_002531761.1	Code: K; COG: COG0640
YP_002531762.1	Code: S; COG: COG1565
YP_002531763.1	Code: R; COG: COG0491
YP_002531765.1	Code: KG; COG: COG1940
YP_002531766.1	Code: S; COG: COG4483
YP_002531767.1	Code: H; COG: COG0212
YP_002531769.1	Code: MJ; COG: COG1208
YP_002531770.1	Code: P; COG: COG0704
YP_002531771.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_002531772.1	Code: P; COG: COG0581
YP_002531773.1	Code: P; COG: COG0573
YP_002531774.1	Code: P; COG: COG0226
YP_002531775.1	Code: M; COG: COG0768
YP_002531776.1	Code: GEPR; COG: COG0477
YP_002531777.1	Code: P; COG: COG0605
YP_002531780.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_002531781.1	Code: P; COG: COG0735
YP_002531782.1	Code: P; COG: COG1108
YP_002531785.1	Code: S; COG: COG1284
YP_002531788.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
YP_002531789.1	Code: LKJ; COG: COG0513
YP_002531791.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_002531793.1	Code: R; COG: COG2384
YP_002531794.1	Code: C; COG: COG2010
YP_002531795.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium
YP_002531796.1	synthesizes RNA primers at the replication forks
YP_002531798.1	Code: S; COG: COG1806
YP_002531799.1	Code: R; COG: COG0517
YP_002531800.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_002531802.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002531803.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002531804.1	Code: M; COG: COG0818
YP_002531805.1	Code: R; COG: COG0319
YP_002531806.1	Code: R; COG: COG1480
YP_002531807.1	Code: T; COG: COG1702
YP_002531810.1	Code: S; COG: COG1610
YP_002531811.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002531812.1	Code: J; COG: COG0621
YP_002531813.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002531814.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_002531815.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002531816.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002531817.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_002531818.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_002531819.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002531820.1	Code: K; COG: COG1733
YP_002531821.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002531823.1	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YP_002531824.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002531825.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_002531828.1	Code: F; COG: COG2131
YP_002531829.1	Code: L; COG: COG1555
YP_002531830.1	may be involved in regulation of competence genes
YP_002531831.1	Code: QR; COG: COG0500
YP_002531832.1	Code: S; COG: COG0799
YP_002531833.1	Code: H; COG: COG1713
YP_002531834.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_002531835.1	Code: J; COG: COG1534
YP_002531836.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002531837.1	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
YP_002531838.1	Code: R; COG: COG2179
YP_002531840.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
YP_002531841.1	sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment
YP_002531844.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002531845.1	Code: S; COG: COG2357
YP_002531847.1	Code: P; COG: COG1785
YP_002531851.1	Code: S; COG: COG2259
YP_002531857.1	Code: O; COG: COG1404
YP_002531858.1	phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin
YP_002531860.1	Code: R; COG: COG2514
YP_002531861.1	Code: S; COG: COG2259
YP_002531862.1	Code: K; COG: COG1396
YP_002531863.1	Code: I; COG: COG2030
YP_002531864.1	Code: KR; COG: COG0454
YP_002531865.1	Code: J; COG: COG1670
YP_002531867.1	Code: PH; COG: COG1120
YP_002531868.1	Code: P; COG: COG0609
YP_002531869.1	Code: P; COG: COG0614
YP_002531872.1	catalyzes the formation of L-homocysteine from cystathionine
YP_002531873.1	Code: E; COG: COG0031
YP_002531874.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_002531875.1	Code: QR; COG: COG0500
YP_002531878.1	Code: M; COG: COG0768
YP_002531879.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002531880.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_002531881.1	Code: O; COG: COG0826
YP_002531882.1	Code: O; COG: COG0826
YP_002531883.1	Code: R; COG: COG4122
YP_002531884.1	Code: R; COG: COG1559
YP_002531885.1	Code: S; COG: COG3906
YP_002531886.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_002531887.1	Code: S; COG: COG4472
YP_002531888.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002531890.1	Code: R; COG: COG0628
YP_002531894.1	Code: L; COG: COG0507
YP_002531895.1	Code: R; COG: COG0457
YP_002531896.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002531897.1	Code: E; COG: COG1104
YP_002531898.1	Code: K; COG: COG1959
YP_002531900.1	Code: L; COG: COG2256
YP_002531902.1	Code: H; COG: COG1179
YP_002531903.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002531904.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002531908.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine
YP_002531909.1	Code: TK; COG: COG0317
YP_002531910.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002531911.1	Code: L; COG: COG0608
YP_002531912.1	Code: P; COG: COG0053
YP_002531913.1	part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002531915.1	Code: R; COG: COG2244
YP_002531916.1	Code: S; COG: COG2323
YP_002531918.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_002531919.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_002531920.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_002531922.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002531923.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002531924.1	Code: P; COG: COG0614
YP_002531926.1	Code: GER; COG: COG0697
YP_002531927.1	Code: K; COG: COG0640
YP_002531932.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_002531933.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
YP_002531934.1	catalyzes the formation of oxaloacetate from L-aspartate
YP_002531935.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
YP_002531936.1	Code: R; COG: COG1827
YP_002531937.1	Code: S; COG: COG2258
YP_002531938.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_002531939.1	Code: V; COG: COG0577
YP_002531940.1	Code: V; COG: COG0577
YP_002531941.1	Code: V; COG: COG1136
YP_002531942.1	Code: T; COG: COG0642
YP_002531943.1	Code: TK; COG: COG0745
YP_002531944.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002531946.1	involved in the peptidyltransferase reaction during translation
YP_002531947.1	Code: J; COG: COG2868
YP_002531948.1	Code: J; COG: COG0261
YP_002531949.1	Code: J; COG: COG1530
YP_002531950.1	Code: R; COG: COG1994
YP_002531951.1	Code: M; COG: COG0739
YP_002531952.1	Code: D; COG: COG2894
YP_002531953.1	blocks the formation of polar Z-ring septums
YP_002531954.1	Code: M; COG: COG2891
YP_002531955.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_002531956.1	functions in MreBCD complex in some organisms
YP_002531957.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_002531958.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002531960.1	Code: H; COG: COG0285
YP_002531961.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002531964.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_002531965.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_002531966.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
YP_002531967.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_002531968.1	Code: O; COG: COG0755
YP_002531969.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_002531970.1	Code: K; COG: COG1846
YP_002531971.1	Code: O; COG: COG1764
YP_002531972.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_002531973.1	Code: O; COG: COG0466
YP_002531974.1	Code: O; COG: COG1067
YP_002531975.1	binds and unfolds substrates as part of the ClpXP protease
YP_002531976.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002531986.1	COG1396
YP_002531990.1	Code: L; COG: COG1961
YP_002531999.1	Code: R; COG: COG0622
YP_002532000.1	hydrolyzes non-standard nucleotides such as xanthine and inosine
YP_002532001.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_002532002.1	Code: R; COG: COG5401
YP_002532003.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_002532004.1	Code: GEPR; COG: COG0477
YP_002532005.1	Code: R; COG: COG0693
YP_002532007.1	Code: R; COG: COG0693
YP_002532018.1	Code: L; COG: COG0608
YP_002532026.1	Code: F; COG: COG2233
YP_002532027.1	metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain
YP_002532028.1	Code: K; COG: COG1396
YP_002532030.1	Code: G; COG: COG0580
YP_002532031.1	Code: K; COG: COG1959
YP_002532033.1	Code: R; COG: COG4152
YP_002532034.1	Code: R; COG: COG2503
YP_002532035.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002532036.1	With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.
YP_002532037.1	Code: M; COG: COG1876
YP_002532038.1	Code: R; COG: COG0824
YP_002532039.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002532040.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_002532041.1	Code: C; COG: COG2009
YP_002532043.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002532044.1	Code: OC; COG: COG0526
YP_002532045.1	Code: C; COG: COG2025
YP_002532046.1	Code: C; COG: COG2086
YP_002532047.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002532048.1	Code: K; COG: COG1309
YP_002532049.1	activates fatty acids by binding to coenzyme A
YP_002532052.1	Code: S; COG: COG2318
YP_002532053.1	Code: R; COG: COG1277
YP_002532055.1	Code: R; COG: COG1277
YP_002532056.1	Code: V; COG: COG1131
YP_002532057.1	Code: T; COG: COG0642
YP_002532058.1	Code: TK; COG: COG0745
YP_002532060.1	Code: S; COG: COG4895
YP_002532061.1	Code: R; COG: COG1092
YP_002532062.1	Code: P; COG: COG0025
YP_002532063.1	iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source
YP_002532064.1	Code: S; COG: COG4509
YP_002532065.1	Code: PH; COG: COG1120
YP_002532066.1	Code: P; COG: COG0609
YP_002532067.1	Code: P; COG: COG0614
YP_002532069.1	Code: M; COG: COG5386
YP_002532070.1	Code: E; COG: COG1114
YP_002532071.1	Code: J; COG: COG1187
YP_002532073.1	MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange
YP_002532075.1	Code: R; COG: COG1286
YP_002532076.1	Code: S; COG: COG3027
YP_002532077.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_002532080.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002532081.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002532082.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002532083.1	Code: J; COG: COG0566
YP_002532085.1	Code: R; COG: COG1418
YP_002532087.1	Code: GEPR; COG: COG0477
YP_002532088.1	Code: V; COG: COG1566
YP_002532089.1	Code: K; COG: COG1309
YP_002532090.1	Code: G; COG: COG1363
YP_002532091.1	Code: S; COG: COG4508
YP_002532092.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002532093.1	Code: J; COG: COG0291
YP_002532094.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_002532095.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_002532097.1	Primosomal protein that may act to load helicase DnaC during DNA replication
YP_002532098.1	Code: L; COG: COG3611
YP_002532099.1	Code: K; COG: COG1327
YP_002532100.1	Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_002532101.1	NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis
YP_002532102.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_002532103.1	Code: S; COG: COG1971
YP_002532104.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_002532105.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_002532106.1	Code: T; COG: COG0642
YP_002532107.1	Code: TK; COG: COG0745
YP_002532111.1	Catalyzes the reversible oxidation of malate to oxaloacetate
YP_002532112.1	Converts isocitrate to alpha ketoglutarate
YP_002532113.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
YP_002532114.1	Code: S; COG: COG2707
YP_002532115.1	Code: R; COG: COG0628
YP_002532116.1	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
YP_002532117.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002532118.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_002532119.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_002532120.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_002532121.1	Code: K; COG: COG2186
YP_002532122.1	Code: C; COG: COG0281
YP_002532123.1	catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.
YP_002532124.1	COG0477
YP_002532126.1	Code: R; COG: COG0618
YP_002532131.1	Code: K; COG: COG4109
YP_002532133.1	catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins
YP_002532134.1	Code: E; COG: COG0006
YP_002532139.1	Code: K; COG: COG1595
YP_002532142.1	Code: G; COG: COG0662
YP_002532144.1	Code: L; COG: COG2963
YP_002532145.1	Code: L; COG: COG2801
YP_002532146.1	Code: E; COG: COG0686
YP_002532147.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002532148.1	Code: T; COG: COG0589
YP_002532154.1	Code: L; COG: COG4584
YP_002532155.1	Code: L; COG: COG1484
YP_002532159.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_002532160.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_002532164.1	Code: S; COG: COG1284
YP_002532167.1	Code: LR; COG: COG0494
YP_002532168.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002532169.1	Code: L; COG: COG0827
YP_002532170.1	Code: O; COG: COG2077
YP_002532171.1	Code: S; COG: COG3874
YP_002532173.1	catalyzes the phosphorylation of NAD to NADP
YP_002532174.1	Code: R; COG: COG1574
YP_002532175.1	Code: S; COG: COG2764
YP_002532176.1	Code: I; COG: COG0365
YP_002532178.1	Required for the synthesis of the thiazole moiety
YP_002532179.1	Code: E; COG: COG1104
YP_002532180.1	acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation
YP_002532182.1	Code: GER; COG: COG0697
YP_002532183.1	Code: K; COG: COG1309
YP_002532184.1	Code: T; COG: COG1956
YP_002532185.1	catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine
YP_002532186.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002532189.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_002532193.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
YP_002532195.1	Code: R; COG: COG0517
YP_002532196.1	Code: BQ; COG: COG0123
YP_002532199.1	Code: TK; COG: COG0745
YP_002532200.1	Code: T; COG: COG0642
YP_002532202.1	Code: R; COG: COG0673
YP_002532203.1	homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_002532207.1	Code: K; COG: COG1609
YP_002532210.1	Code: R; COG: COG4768
YP_002532212.1	Code: E; COG: COG2309
YP_002532214.1	Code: KR; COG: COG0454
YP_002532215.1	Code: J; COG: COG1670
YP_002532216.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002532217.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_002532220.1	Code: R; COG: COG0073
YP_002532221.1	Code: S; COG: COG4848
YP_002532222.1	Code: OC; COG: COG0526
YP_002532223.1	pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog
YP_002532224.1	Code: G; COG: COG1363
YP_002532225.1	Code: S; COG: COG5584
YP_002532226.1	Code: R; COG: COG0491
YP_002532227.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_002532229.1	Code: M; COG: COG0510
YP_002532230.1	Code: G; COG: COG1523
YP_002532231.1	Code: J; COG: COG1514
YP_002532232.1	divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases
YP_002532233.1	Code: KG; COG: COG1349
YP_002532234.1	Code: J; COG: COG1187
YP_002532235.1	export protein for polysaccharides and teichoic acids; Code: R; COG: COG2244
YP_002532237.1	Code: R; COG: COG2081
YP_002532238.1	Code: GEPR; COG: COG0477
YP_002532239.1	Code: K; COG: COG0640
YP_002532240.1	Code: S; COG: COG3832
YP_002532243.1	Code: K; COG: COG1329
YP_002532244.1	Converts glucose to D-glucono-1,5 lactone
YP_002532245.1	Code: G; COG: COG4975
YP_002532247.1	Code: H; COG: COG1977
YP_002532248.1	Code: H; COG: COG0314
YP_002532249.1	Code: L; COG: COG0675
YP_002532251.1	Code: H; COG: COG1763
YP_002532252.1	Code: H; COG: COG0303
YP_002532253.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
YP_002532254.1	catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways
YP_002532255.1	Code: H; COG: COG2896
YP_002532259.1	Code: P; COG: COG0607
YP_002532261.1	catalyzes the formation of O-acetyl -L-homoserine from L-homoserine and acetyl-CoA
YP_002532266.1	Code: S; COG: COG4696
YP_002532268.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002532269.1	Code: GEPR; COG: COG0477
YP_002532270.1	Code: P; COG: COG0475
YP_002532271.1	Code: P; COG: COG0490
YP_002532272.1	Code: L; COG: COG0582
YP_002532274.1	Code: V; COG: COG1136
YP_002532278.1	Code: R; COG: COG1242
YP_002532279.1	Code: QR; COG: COG0500
YP_002532280.1	Code: V; COG: COG1131
YP_002532282.1	Code: M; COG: COG1794
YP_002532284.1	Code: S; COG: COG3182
YP_002532288.1	Code: I; COG: COG2267
YP_002532289.1	Code: R; COG: COG0663
YP_002532290.1	Code: I; COG: COG0671
YP_002532291.1	Code: M; COG: COG0438
YP_002532292.1	Code: H; COG: COG0746
YP_002532293.1	Code: H; COG: COG0521
YP_002532296.1	Code: J; COG: COG1670
YP_002532297.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002532298.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_002532302.1	Code: S; COG: COG4918
YP_002532306.1	Code: R; COG: COG0596
YP_002532307.1	Code: M; COG: COG1368
YP_002532308.1	COG1807
YP_002532312.1	Code: P; COG: COG1116
YP_002532313.1	Code: P; COG: COG0600
YP_002532316.1	Code: R; COG: COG1011
YP_002532318.1	Code: LR; COG: COG0494
YP_002532321.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_002532322.1	Code: S; COG: COG0759
YP_002532323.1	Code: P; COG: COG0288
YP_002532324.1	Code: C; COG: COG1271
YP_002532325.1	Code: C; COG: COG1294
YP_002532329.1	Code: S; COG: COG1434
YP_002532330.1	Code: S; COG: COG1284
YP_002532334.1	Code: S; COG: COG3766
YP_002532335.1	Code: KT; COG: COG1842
YP_002532337.1	Code: P; COG: COG0370
YP_002532338.1	Code: P; COG: COG1918
YP_002532339.1	Code: S; COG: COG3859
YP_002532341.1	Code: TK; COG: COG0745
YP_002532342.1	Code: M; COG: COG3764
YP_002532347.1	Code: F; COG: COG0634
YP_002532348.1	Code: IR; COG: COG1597
YP_002532352.1	Code: V; COG: COG0577
YP_002532353.1	Code: V; COG: COG1136
YP_002532355.1	Code: S; COG: COG5294
YP_002532356.1	Code: S; COG: COG0586
YP_002532357.1	Code: I; COG: COG3963
YP_002532360.1	Code: L; COG: COG2801
YP_002532361.1	Code: L; COG: COG2963
YP_002532362.1	Code: V; COG: COG0577
YP_002532363.1	Code: V; COG: COG1136
YP_002532365.1	Code: S; COG: COG5658
YP_002532366.1	Code: K; COG: COG0640
YP_002532367.1	Code: TK; COG: COG0745
YP_002532368.1	Code: T; COG: COG0642
YP_002532369.1	Code: V; COG: COG0577
YP_002532370.1	Code: V; COG: COG0577
YP_002532371.1	Code: V; COG: COG1136
YP_002532372.1	Code: V; COG: COG0577
YP_002532374.1	Code: GE; COG: COG2610
YP_002532375.1	Code: K; COG: COG2188
YP_002532376.1	Code: G; COG: COG0524
YP_002532378.1	Code: E; COG: COG1921
YP_002532379.1	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides
YP_002532380.1	Code: M; COG: COG1876
YP_002532381.1	Code: T; COG: COG0642
YP_002532382.1	Code: TK; COG: COG0745
YP_002532383.1	Code: MR; COG: COG4948
YP_002532384.1	converts O-succinylbenzoate to O-succinylbenzoyl-CoA
YP_002532386.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_002532387.1	Code: R; COG: COG0596
YP_002532388.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
YP_002532389.1	Code: HQ; COG: COG1169
YP_002532390.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_002532391.1	Code: T; COG: COG1734
YP_002532392.1	Code: K; COG: COG1278
YP_002532393.1	Code: S; COG: COG2013
YP_002532396.1	Code: G; COG: COG0058
YP_002532397.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_002532398.1	Code: G; COG: COG0448
YP_002532399.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_002532400.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_002532404.1	Converts (S)-lactate and NAD(+) to pyruvate and NADH
YP_002532407.1	Code: S; COG: COG1285
YP_002532408.1	Code: P; COG: COG1226
YP_002532410.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002532411.1	Code: S; COG: COG2155
YP_002532412.1	induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation
YP_002532413.1	Code: E; COG: COG0436
YP_002532414.1	Code: K; COG: COG1522
YP_002532415.1	Code: CHR; COG: COG1052
YP_002532416.1	Code: R; COG: COG0596
YP_002532418.1	Code: E; COG: COG1168
YP_002532419.1	Code: P; COG: COG2032
YP_002532422.1	inhibitor of the KinA pathway of sporulation
YP_002532423.1	Code: P; COG: COG1055
YP_002532425.1	Code: L; COG: COG4912
YP_002532426.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002532427.1	Code: Q; COG: COG2050
YP_002532429.1	Code: R; COG: COG1268
YP_002532430.1	Code: M; COG: COG1210
YP_002532431.1	Code: G; COG: COG1109
YP_002532432.1	Code: S; COG: COG1624
YP_002532433.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_002532434.1	Code: S; COG: COG3584
YP_002532436.1	Code: F; COG: COG1051
YP_002532437.1	Code: C; COG: COG1252
YP_002532438.1	Code: O; COG: COG0492
YP_002532439.1	Code: S; COG: COG3708
YP_002532440.1	Code: GEPR; COG: COG0477
YP_002532442.1	Code: S; COG: COG1683
YP_002532443.1	Code: S; COG: COG5294
YP_002532444.1	Code: J; COG: COG1670
YP_002532445.1	Code: S; COG: COG0316
YP_002532446.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_002532447.1	Code: S; COG: COG4844
YP_002532448.1	Code: C; COG: COG1252
YP_002532449.1	Code: V; COG: COG1136
YP_002532450.1	Code: R; COG: COG0390
YP_002532451.1	Code: P; COG: COG2824
YP_002532459.1	Code: S; COG: COG4837
YP_002532460.1	Code: O; COG: COG0694
YP_002532463.1	Code: I; COG: COG1267
YP_002532465.1	Code: R; COG: COG2249
YP_002532467.1	Code: G; COG: COG0647
YP_002532468.1	Code: K; COG: COG2345
YP_002532469.1	Code: S; COG: COG2445
YP_002532470.1	similar to GlpX type II fructose-1,6-bisphosphatase
YP_002532473.1	Code: S; COG: COG4470
YP_002532475.1	Code: K; COG: COG0789
YP_002532476.1	Code: S; COG: COG4377
YP_002532478.1	Code: G; COG: COG0406
YP_002532480.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002532481.1	Code: M; COG: COG0739
YP_002532483.1	Code: S; COG: COG3377
YP_002532484.1	Code: F; COG: COG0737
YP_002532485.1	Code: O; COG: COG0719
YP_002532486.1	Code: C; COG: COG0822
YP_002532487.1	Code: E; COG: COG0520
YP_002532488.1	Code: O; COG: COG0719
YP_002532489.1	Code: O; COG: COG0396
YP_002532491.1	Code: P; COG: COG1464
YP_002532492.1	Code: P; COG: COG1464
YP_002532493.1	Code: P; COG: COG2011
YP_002532494.1	Code: P; COG: COG1135
YP_002532496.1	Code: OC; COG: COG0526
YP_002532497.1	Code: L; COG: COG1658
YP_002532498.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_002532499.1	Code: P; COG: COG1393
YP_002532502.1	Code: I; COG: COG0671
YP_002532503.1	Code: R; COG: COG3641
YP_002532504.1	Converts (S)-lactate and NAD(+) to pyruvate and NADH
YP_002532509.1	Code: K; COG: COG1476
YP_002532511.1	Code: K; COG: COG1309
YP_002532512.1	Code: R; COG: COG0491
YP_002532513.1	Code: I; COG: COG1960
YP_002532514.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002532518.1	Code: M; COG: COG1686
YP_002532519.1	Code: E; COG: COG0506
YP_002532521.1	Code: S; COG: COG0011
YP_002532523.1	Code: L; COG: COG0675
YP_002532527.1	Code: G; COG: COG2814
YP_002532528.1	Code: E; COG: COG0531
YP_002532531.1	involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site
YP_002532533.1	Code: S; COG: COG1284
YP_002532534.1	Code: J; COG: COG1670
YP_002532539.1	Code: K; COG: COG1476
YP_002532540.1	Code: S; COG: COG0586
YP_002532542.1	Code: S; COG: COG1376
YP_002532543.1	Code: TK; COG: COG0745
YP_002532545.1	Code: GER; COG: COG0697
YP_002532546.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002532547.1	Code: QR; COG: COG0500
YP_002532548.1	Code: NT; COG: COG0840
YP_002532549.1	Code: NT; COG: COG0840
YP_002532550.1	Code: R; COG: COG2151
YP_002532551.1	Code: E; COG: COG3227
YP_002532552.1	Code: R; COG: COG1741
YP_002532553.1	Code: K; COG: COG1846
YP_002532555.1	Code: P; COG: COG0475
YP_002532556.1	Code: P; COG: COG0490
YP_002532557.1	Code: E; COG: COG1115
YP_002532558.1	Code: P; COG: COG0783
YP_002532561.1	Code: R; COG: COG1611
YP_002532562.1	Code: R; COG: COG1694
YP_002532563.1	Code: P; COG: COG1528
YP_002532565.1	Code: F; COG: COG1972
YP_002532566.1	Code: F; COG: COG1972
YP_002532567.1	Code: E; COG: COG1115
YP_002532568.1	Code: E; COG: COG1115
YP_002532569.1	Code: R; COG: COG2910
YP_002532572.1	Code: R; COG: COG0656
YP_002532573.1	Code: G; COG: COG2814
YP_002532574.1	Code: K; COG: COG1733
YP_002532575.1	Code: S; COG: COG2427
YP_002532576.1	Code: C; COG: COG1252
YP_002532577.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_002532578.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002532581.1	Code: R; COG: COG2940
YP_002532584.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002532585.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002532588.1	Code: GEPR; COG: COG0477
YP_002532590.1	Code: J; COG: COG1670
YP_002532591.1	Code: S; COG: COG3223
YP_002532593.1	Code: P; COG: COG4604
YP_002532594.1	Code: P; COG: COG4605
YP_002532595.1	Code: P; COG: COG4606
YP_002532596.1	Code: P; COG: COG4607
YP_002532597.1	Code: TK; COG: COG0745
YP_002532600.1	Code: V; COG: COG1136
YP_002532601.1	Code: S; COG: COG5294
YP_002532602.1	Code: T; COG: COG0642
YP_002532603.1	Code: TK; COG: COG0745
YP_002532604.1	Code: S; COG: COG0586
YP_002532605.1	Code: I; COG: COG3963
YP_002532617.1	Code: J; COG: COG0223
YP_002532618.1	Code: GEPR; COG: COG0477
YP_002532619.1	Code: G; COG: COG2513
YP_002532620.1	Code: K; COG: COG0640
YP_002532622.1	Code: R; COG: COG1266
YP_002532623.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002532624.1	Code: K; COG: COG0557
YP_002532625.1	Code: R; COG: COG1647
YP_002532626.1	Code: U; COG: COG1314
YP_002532627.1	Code: M; COG: COG1346
YP_002532628.1	increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB
YP_002532629.1	Code: F; COG: COG1957
YP_002532630.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002532631.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_002532632.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002532633.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002532634.1	Code: G; COG: COG0057
YP_002532635.1	Code: K; COG: COG2390
YP_002532636.1	Code: OC; COG: COG0526
YP_002532637.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_002532639.1	Code: R; COG: COG4152
YP_002532641.1	Code: V; COG: COG2274
YP_002532645.1	Code: TK; COG: COG2197
YP_002532660.1	Code: S; COG: COG2323
YP_002532661.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002532662.1	Code: G; COG: COG1925
YP_002532663.1	Code: S; COG: COG1481
YP_002532664.1	Code: S; COG: COG0391
YP_002532665.1	Code: R; COG: COG1660
YP_002532666.1	Code: LR; COG: COG0494
YP_002532667.1	Code: S; COG: COG2035
YP_002532668.1	Code: O; COG: COG0492
YP_002532669.1	Code: R; COG: COG0457
YP_002532670.1	Code: R; COG: COG0110
YP_002532671.1	hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation
YP_002532672.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002532673.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
YP_002532674.1	Code: S; COG: COG1950
YP_002532677.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002532678.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002532685.1	Code: K; COG: COG1476
YP_002532686.1	Code: S; COG: COG2855
YP_002532687.1	Code: K; COG: COG0583
YP_002532689.1	Code: R; COG: COG0655
YP_002532691.1	Code: S; COG: COG0393
YP_002532692.1	Code: V; COG: COG1132
YP_002532693.1	Code: O; COG: COG0265
YP_002532694.1	Code: M; COG: COG0793
YP_002532695.1	Code: D; COG: COG2177
YP_002532696.1	Code: D; COG: COG2884
YP_002532697.1	Code: C; COG: COG2010
YP_002532698.1	catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA
YP_002532699.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002532700.1	Code: J; COG: COG1544
YP_002532701.1	Code: K; COG: COG1278
YP_002532702.1	Code: R; COG: COG1040
YP_002532703.1	Code: L; COG: COG4098
YP_002532705.1	Code: K; COG: COG1733
YP_002532707.1	Code: S; COG: COG1307
YP_002532708.1	Code: S; COG: COG1739
YP_002532709.1	Code: K; COG: COG1316
YP_002532710.1	Code: M; COG: COG0381
YP_002532711.1	Code: M; COG: COG1004
YP_002532713.1	Code: M; COG: COG0472
YP_002532718.1	Code: P; COG: COG2059
YP_002532719.1	Code: S; COG: COG3394
YP_002532720.1	Code: G; COG: COG1486
YP_002532721.1	Code: G; COG: COG1447
YP_002532722.1	Code: G; COG: COG1455
YP_002532723.1	Code: G; COG: COG1440
YP_002532724.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_002532725.1	Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_002532727.1	Code: KT; COG: COG3279
YP_002532728.1	Code: G; COG: COG1447
YP_002532729.1	Code: G; COG: COG1455
YP_002532730.1	Code: G; COG: COG1440
YP_002532733.1	Code: E; COG: COG0346
YP_002532734.1	Code: M; COG: COG3764
YP_002532738.1	Code: K; COG: COG0583
YP_002532741.1	Code: C; COG: COG1271
YP_002532742.1	Code: C; COG: COG1294
YP_002532743.1	Code: P; COG: COG1055
YP_002532744.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_002532745.1	Code: C; COG: COG1620
YP_002532747.1	Code: R; COG: COG2389
YP_002532748.1	Code: S; COG: COG3339
YP_002532749.1	Code: M; COG: COG1368
YP_002532751.1	catalyzes the transamination of D-amino acids and their alpha-keto acids
YP_002532753.1	Code: F; COG: COG1972
YP_002532756.1	Code: M; COG: COG1215
YP_002532757.1	Code: M; COG: COG1292
YP_002532762.1	COG0419
YP_002532764.1	Code: KL; COG: COG0553
YP_002532765.1	Code: S; COG: COG5652
YP_002532770.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002532772.1	Code: V; COG: COG0577
YP_002532773.1	Code: V; COG: COG1136
YP_002532775.1	Code: G; COG: COG2271
YP_002532776.1	Code: P; COG: COG1840
YP_002532779.1	Code: TK; COG: COG0745
YP_002532780.1	Code: G; COG: COG1482
YP_002532782.1	Code: K; COG: COG3711
YP_002532783.1	Code: G; COG: COG1109
YP_002532784.1	Code: M; COG: COG1087
YP_002532785.1	Code: M; COG: COG1087
YP_002532786.1	Code: M; COG: COG4750
YP_002532787.1	Code: GER; COG: COG0697
YP_002532789.1	Code: R; COG: COG2244
YP_002532793.1	attenuator function for control of operon expression
YP_002532794.1	Code: G; COG: COG1482
YP_002532796.1	Code: M; COG: COG0438
YP_002532797.1	Code: M; COG: COG0438
YP_002532800.1	Code: M; COG: COG2148
YP_002532801.1	Code: M; COG: COG1210
YP_002532802.1	Code: GM; COG: COG4464
YP_002532803.1	Code: D; COG: COG0489
YP_002532804.1	Code: M; COG: COG3944
YP_002532805.1	Code: D; COG: COG0489
YP_002532806.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_002532808.1	Code: D; COG: COG1077
YP_002532811.1	Code: M; COG: COG0739
YP_002532812.1	Code: V; COG: COG0842
YP_002532813.1	Code: V; COG: COG1131
YP_002532815.1	Code: D; COG: COG2385
YP_002532816.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002532818.1	Code: S; COG: COG4836
YP_002532819.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532820.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532821.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002532822.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532823.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532824.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532825.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002532826.1	catalyzes the transfer of electrons from NADH to ubiquinone
YP_002532827.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002532828.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_002532829.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002532833.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_002532834.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_002532835.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_002532836.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002532837.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_002532838.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_002532839.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_002532840.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_002532844.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_002532845.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002532846.1	Code: S; COG: COG4475
YP_002532847.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_002532848.1	Code: T; COG: COG0394
YP_002532849.1	Code: G; COG: COG2190
YP_002532850.1	Code: S; COG: COG2259
YP_002532851.1	Code: R; COG: COG1853
YP_002532854.1	Code: S; COG: COG1971
YP_002532855.1	Code: J; COG: COG0009
YP_002532858.1	Code: J; COG: COG2890
YP_002532859.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002532860.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_002532861.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002532862.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_002532864.1	Code: M; COG: COG0766
YP_002532865.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_002532866.1	Code: T; COG: COG0784
YP_002532868.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002532869.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
YP_002532870.1	Code: K; COG: COG1309
YP_002532871.1	Code: I; COG: COG1960
YP_002532872.1	Code: I; COG: COG1960
YP_002532873.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_002532874.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002532875.1	Code: C; COG: COG0247
YP_002532876.1	Code: I; COG: COG1502
YP_002532877.1	Code: L; COG: COG4294
YP_002532882.1	Code: TK; COG: COG2197
YP_002532883.1	Code: T; COG: COG4585
YP_002532884.1	Code: V; COG: COG0842
YP_002532885.1	Code: V; COG: COG1131
YP_002532886.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential
YP_002532888.1	Code: R; COG: COG2234
YP_002532892.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002532893.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002532894.1	Code: S; COG: COG4506
YP_002532895.1	Code: V; COG: COG1619
YP_002532897.1	Code: G; COG: COG1299
YP_002532898.1	Code: E; COG: COG0010
YP_002532899.1	Code: E; COG: COG0421
YP_002532900.1	Code: GEPR; COG: COG0477
YP_002532901.1	Code: K; COG: COG0789
YP_002532902.1	Code: C; COG: COG0584
YP_002532903.1	Code: M; COG: COG0744
YP_002532905.1	Code: R; COG: COG1994
YP_002532907.1	4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown
YP_002532908.1	Code: R; COG: COG1078
YP_002532910.1	Code: PH; COG: COG1120
YP_002532911.1	Code: P; COG: COG0609
YP_002532912.1	Code: P; COG: COG0609
YP_002532916.1	Code: H; COG: COG0095
YP_002532917.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_002532918.1	Code: S; COG: COG3253
YP_002532919.1	Code: M; COG: COG1686
YP_002532920.1	Code: M; COG: COG3773
YP_002532922.1	Code: S; COG: COG2363
YP_002532924.1	Code: P; COG: COG1226
YP_002532925.1	Code: F; COG: COG2233
YP_002532929.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002532930.1	Code: R; COG: COG1277
YP_002532931.1	Code: V; COG: COG1131
YP_002532932.1	Code: E; COG: COG2755
YP_002532933.1	Code: K; COG: COG1609
YP_002532935.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_002532936.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_002532937.1	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
YP_002532938.1	Code: R; COG: COG1011
YP_002532939.1	activator of nucleoside metabolism
YP_002532940.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
YP_002532941.1	Code: TK; COG: COG2197
YP_002532943.1	catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine
YP_002532944.1	Code: T; COG: COG2199
YP_002532945.1	Code: S; COG: COG2879
YP_002532946.1	Code: T; COG: COG1966
YP_002532948.1	Code: GEPR; COG: COG0477
YP_002532949.1	Code: M; COG: COG1922
YP_002532952.1	Code: S; COG: COG2860
YP_002532953.1	Code: NT; COG: COG0840
YP_002532955.1	Code: I; COG: COG1607
YP_002532956.1	Code: M; COG: COG0463
YP_002532958.1	COG1807
YP_002532959.1	Code: M; COG: COG0463
YP_002532962.1	Code: R; COG: COG0488
YP_002532964.1	Code: L; COG: COG4584
YP_002532965.1	Code: L; COG: COG1484
YP_002532966.1	Code: K; COG: COG1309
YP_002532967.1	Code: V; COG: COG0841
YP_002532969.1	Code: R; COG: COG0628
YP_002532970.1	in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases
YP_002532971.1	negatively regulates murein hydrolase activity
YP_002532972.1	Code: KT; COG: COG3279
YP_002532973.1	Code: T; COG: COG3275
YP_002532976.1	Code: M; COG: COG1292
YP_002532977.1	Code: PE; COG: COG4362
YP_002532978.1	Code: P; COG: COG0605
YP_002532979.1	Code: MG; COG: COG0451
YP_002532984.1	Code: S; COG: COG4878
YP_002532985.1	Code: M; COG: COG0438
YP_002532986.1	similar to TM1408; Code: S; COG: COG4267
YP_002532987.1	Code: M; COG: COG1087
YP_002532988.1	Code: R; COG: COG1272
YP_002532990.1	Code: LKJ; COG: COG0513
YP_002532991.1	Code: F; COG: COG0516
YP_002532992.1	Code: E; COG: COG1164
YP_002532994.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_002532996.1	Code: O; COG: COG0265
YP_002532997.1	Code: R; COG: COG1235
YP_002532998.1	Code: S; COG: COG4853
YP_002533000.1	Code: T; COG: COG5002
YP_002533001.1	Code: TK; COG: COG0745
YP_002533002.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_002533003.1	unwinds double stranded DNA
YP_002533004.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002533005.1	Code: T; COG: COG3887
YP_002533007.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002533008.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_002533009.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002533010.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002533011.1	Code: S; COG: COG4481
YP_002533012.1	Code: M; COG: COG0668
YP_002533014.1	Code: K; COG: COG1475
YP_002533015.1	Code: D; COG: COG1192
YP_002533016.1	Code: K; COG: COG1475
YP_002533017.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_002533018.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_002533019.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_002533020.1	Code: R; COG: COG1847
YP_002533021.1	involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation
YP_002533022.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_002533023.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002533107.1	similar to [Escherichia coli],DNA-invertase - Shigella boydii
YP_002533111.1	Positive regulatory protein that acts at the late promoter PL
YP_002533233.1	similar to Enterococcus faecium transposon Tn1546 resolvase
YP_002533263.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS
YP_002533285.1	similar to Escherichia coli plasmid R68.45 insertion sequence IS21
YP_002533354.1	Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine