-- dump date 20120504_134151 -- class Genbank::CDS -- table cds_note -- id note YP_089685.1 initiation of chromosome replication; binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself YP_089686.1 DNA polymerase III (beta subunit); binds the polymerase to DNA and acts as a sliding clamp YP_089687.1 RBL05527 YP_089688.1 DNA repair and genetic recombination; Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_089689.1 RBL05528 YP_089690.1 DNA gyrase (subunit B); negatively supercoils closed circular double-stranded DNA YP_089691.1 DNA gyrase (subunit A); negatively supercoils closed circular double-stranded DNA YP_089692.1 RBL00486 YP_089693.1 inosine-monophosphate dehydrogenase; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_089694.1 penicillin-binding protein 5 (D-alanyl-D-alanine carboxypeptidase); RBL00489 YP_089695.1 similar to superoxide-inducible protein; with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_089696.1 similar to amidotransferase; with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_089697.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_089698.1 similar to gluconate permease; RBL00495 YP_089699.1 RBL00496 YP_089700.1 RBL00497 YP_089701.1 RBL05874 YP_089702.1 RBL02751 YP_089703.1 similar to proteins from B. subtilis; RBL02752 YP_089704.1 similar to isochorismatase; RBL02753 YP_089705.1 similar to Cu binding protein (Mn oxidation); RBL02754 YP_089706.1 DNA polymerase III (gamma and tau subunits); catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_089707.1 RBL02758 YP_089708.1 DNA repair and genetic recombination; involved in a recombinational process of DNA repair, independent of the recBC complex YP_089709.1 RBL05875 YP_089710.1 inhibition of the pro-sigma-K processing machinery; RBL05499 YP_089711.1 hydrolysis of 5-bromo 4-chloroindolyl phosphate; RBL03145 YP_089712.1 similar to toxic cation resistance; RBL03146 YP_089713.1 similar to lysine decarboxylase; RBL03149 YP_089714.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_089715.1 RBL03151 YP_089716.1 RBL03152 YP_089717.1 DNA polymerase III (delta' subunit); catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_089718.1 RBL03154 YP_089719.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_089720.1 RBL03157 YP_089721.1 RBL05097 YP_089722.1 RBL03158 YP_089723.1 transcriptional pleiotropic regulator of transition state genes; RBL05098 YP_089724.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_089725.1 RBL03161 YP_089726.1 similar to cell wall-binding protein; RBL03162 YP_089727.1 ribonuclease M5; RBL03163 YP_089728.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_089729.1 RBL03165 YP_089730.1 function; RBL05099 YP_089731.1 small acid-soluble spore protein (minor alpha/beta-type SASP); RBL05100 YP_089732.1 probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_089733.1 transcriptional repressor of the purine operons; RBL03167 YP_089734.1 similar to translation initiation inhibitor; RBL03168 YP_089735.1 required for spore cortex synthesis; stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus YP_089736.1 UDP-N-acetylglucosamine pyrophosphorylase; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_089737.1 phosphoribosylpyrophosphate synthetase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_089738.1 general stress protein; the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_089739.1 probable peptidyl-tRNA hydrolase; Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_089740.1 RBL05501 YP_089741.1 transcription-repair coupling factor; RBL03175 YP_089742.1 transcriptional positive and negative regulator of sigma-G-dependent genes; RBL03176 YP_089743.1 similar to amino acid transporter; RBL03178 YP_089744.1 RBL03179 YP_089745.1 RBL05102 YP_089746.1 RBL03181 YP_089747.1 RBL03182 YP_089748.1 cell-division initiation protein (septum formation); RBL03183 YP_089749.1 similar to polyribonucleotide nucleotidyltransferase; RBL05103 YP_089750.1 serine phosphatase (sigma-F activation) / asymmetric septum formation; RBL03184 YP_089751.1 RBL03185 YP_089752.1 similar to serine/threonine-protein kinase; RBL03186 YP_089753.1 similar to cell-cycle protein; RBL03187 YP_089754.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_089755.1 cell-division protein / general stress protein (class III heat-shock); RBL03190 YP_089756.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_089757.1 similar to chaperonin (heat shock protein 33 homolog); becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_089758.1 similar to protein secretion PrsA homolog; RBL03194 YP_089759.1 cysteine synthetase A; RBL03196 YP_089760.1 para-aminobenzoate synthase (subunit A); catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_089761.1 para-aminobenzoate synthase glutamine amidotransferase (subunit B) / anthranilate synthase (subunit II); amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis YP_089762.1 aminodeoxychorismate lyase; catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_089763.1 dihydropteroate synthase; RBL03200 YP_089764.1 dihydroneopterin aldolase; RBL03201 YP_089765.1 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase; RBL05104 YP_089766.1 similar to transcriptional regulator (nitrogen regulation protein); RBL03203 YP_089767.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_089768.1 transcriptional repressor of class III stress genes; RBL03205 YP_089769.1 modulator of CtsR repression; RBL03206 YP_089770.1 modulator of CtsR repression; RBL03207 YP_089771.1 class III stress response-related ATPase; RBL03208 YP_089772.1 DNA repair protein homolog; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_089773.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair YP_089774.1 RBL03211 YP_089775.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_089776.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_089777.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_089778.1 serine acetyltransferase; RBL03215 YP_089779.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_089780.1 RBL03217 YP_089781.1 similar to tRNA/rRNA methyltransferase; RBL03218 YP_089782.1 RBL03219 YP_089783.1 RNA polymerase sigma-H factor (sigma-30); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_089784.1 ribosomal protein L33; in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_089785.1 preprotein translocase secE subunit; forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_089786.1 transcription antitermination factor; Modulates Rho-dependent transcription termination YP_089787.1 ribosomal protein L11 (BL11); binds directly to 23S ribosomal RNA YP_089788.1 ribosomal protein L1 (BL1); in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_089789.1 ribosomal protein L10 (BL5); binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_089790.1 ribosomal protein L12 (BL9); present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_089791.1 RBL00903 YP_089792.1 RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_089793.1 RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_089794.1 similar to ribosomal protein L7AE family; in Bacillus subtilis this non-essential protein associates with the ribosome YP_089795.1 ribosomal protein S12 (BS12); interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_089796.1 ribosomal protein S7 (BS7); binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_089797.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_089798.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_089799.1 ribosomal protein S10 (BS13); NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_089800.1 ribosomal protein L3 (BL3); binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_089801.1 ribosomal protein L4; L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_089802.1 ribosomal protein L23; binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_089803.1 ribosomal protein L2 (BL2); one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_089804.1 ribosomal protein S19 (BS19); protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_089805.1 ribosomal protein L22 (BL17); binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_089806.1 ribosomal protein S3 (BS3); forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_089807.1 ribosomal protein L16; located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_089808.1 ribosomal protein L29; one of the stabilizing components for the large ribosomal subunit YP_089809.1 ribosomal protein S17 (BS16); primary binding protein; helps mediate assembly; involved in translation fidelity YP_089810.1 ribosomal protein L14; binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_089811.1 ribosomal protein L24 (BL23) (histone-like protein HPB12); assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_089812.1 ribosomal protein L5 (BL6); part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_089813.1 ribosomal protein S14; located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_089814.1 ribosomal protein S8 (BS8); binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_089815.1 ribosomal protein L6 (BL8); ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_089816.1 ribosomal protein L18; binds 5S rRNA along with protein L5 and L25 YP_089817.1 ribosomal protein S5; located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_089818.1 ribosomal protein L30 (BL27); L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_089819.1 ribosomal protein L15; late assembly protein YP_089820.1 preprotein translocase subunit; forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_089821.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_089822.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_089823.1 RBL03248 YP_089824.1 initiation factor IF-1; stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_089825.1 ribosomal protein L36 (ribosomal protein B); smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_089826.1 ribosomal protein S13; located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_089827.1 ribosomal protein S11 (BS11); located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_089828.1 RNA polymerase (alpha subunit); catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_089829.1 ribosomal protein L17 (BL15); is a component of the macrolide binding site in the peptidyl transferase center YP_089830.1 similar to ABC transporter (ATP-binding protein); with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_089831.1 similar to ABC transporter (ATP-binding protein); with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene YP_089832.1 RBL01076 YP_089833.1 pseudouridylate synthase I; mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_089834.1 ribosomal protein L13; in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_089835.1 ribosomal protein S9; forms a direct contact with the tRNA during translation YP_089836.1 RBL01079 YP_089837.1 RBL01080 YP_089838.1 N-acetylmuramoyl-L-alanine amidase (germination); RBL01082 YP_089839.1 similar to ATP-binding Mrp-like protein; RBL01083 YP_089840.1 germination response to L-alanine and to the combination of glucose, fructose, L-asparagine, and KCl; RBL01085 YP_089841.1 activation of the KinB signaling pathway to sporulation; RBL01086 YP_089842.1 similar to polysaccharide deacetylase; RBL01087 YP_089843.1 penicillin-binding protein; RBL01088 YP_089844.1 RBL05182 YP_089845.1 similar to sodium dependent transporter; RBL01089 YP_089846.1 RBL04974 YP_089847.1 putative phenazine biosynthesis protein phzF; RBL01090 YP_089848.1 RBL01091 YP_089849.1 similar to beta-hexosaminidase; RBL01094 YP_089850.1 similar to beta-lactamase; RBL01095 YP_089851.1 similar to sucrose phosphotransferase enzyme II; RBL01096 YP_089852.1 RBL01097 YP_089853.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_089854.1 RBL01099 YP_089855.1 close homolog to RocF arginase; RBL01100 YP_089856.1 RNA polymerase ECF-type sigma factor; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial YP_089857.1 RBL01102 YP_089858.1 RBL01103 YP_089859.1 RBL01104 YP_089860.1 similar to phosphoglucomutase (glycolysis); catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_089861.1 L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_089862.1 RBL01118 YP_089863.1 putative transporter; RBL01117 YP_089864.1 putative ABC transporter ATP-binding protein; RBL01116 YP_089865.1 putative transcriptional regulator, GntR family; RBL04973 YP_089866.1 putative transcriptional regulator; RBL03311 YP_089867.1 similar to chloramphenicol resistance protein; RBL03310 YP_089868.1 RBL03309 YP_089869.1 similar to ABC transporter (ATP-binding protein); RBL03308 YP_089870.1 RBL00204 YP_089871.1 RBL00203 YP_089872.1 RBL00202 YP_089873.1 RBL00201 YP_089874.1 RBL00200 YP_089875.1 RBL00199 YP_089876.1 similar to amino acid permease; RBL00198 YP_089877.1 secondary transporter of divalent metal ions/citrate complexes; RBL05183 YP_089878.1 RBL05184 YP_089879.1 two-component response regulator involved in the response to the environmental Mg-citrate complex; RBL02928 YP_089880.1 two-component sensor histidine kinase involved in the response to the environmental Mg-citrate complex; RBL02930 YP_089881.1 putative transcriptional regulator, LysR family; RBL02931 YP_089882.1 putative carboxylase; RBL02932 YP_089883.1 putative transporter; RBL02933 YP_089884.1 sporulation-specific SASP protein; RBL05185 YP_089885.1 RBL05186 YP_089886.1 RBL05187 YP_089887.1 RBL02935 YP_089888.1 RBL05188 YP_089889.1 threonyl-tRNA synthetase (minor); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins YP_089890.1 RBL05878 YP_089891.1 RBL01700 YP_089892.1 RBL01699 YP_089893.1 similar to hemolysin-like; RBL05879 YP_089894.1 similar to hemolysin-like; RBL05880 YP_089895.1 similar to metabolite transport protein; RBL01698 YP_089896.1 putative methyltransferase; RBL01697 YP_089897.1 putative nucleoside-diphosphate-sugar epimerases; RBL05612 YP_089898.1 RBL05881 YP_089899.1 putative sodium-dependent phosphate transporter; RBL00127 YP_089900.1 RBL05495 YP_089901.1 RBL00126 YP_089902.1 RBL00125 YP_089903.1 RBL00124 YP_089904.1 RBL00123 YP_089905.1 RBL00122 YP_089906.1 similar to transcriptional regulator (AraC/XylS family); RBL00121 YP_089907.1 similar to transcriptional regulator (AraC/XylS family); RBL00120 YP_089908.1 RBL05883 YP_089909.1 RBL05884 YP_089910.1 RBL00117 YP_089911.1 putative oxidoreductase; RBL00115 YP_089912.1 similar to methyl-accepting chemotaxis protein; RBL00114 YP_089913.1 putative sugar ABC transporter, periplasmic-binding protein; RBL00113 YP_089914.1 RBL00112 YP_089915.1 RBL05494 YP_089916.1 putative antibiotic hydrolase; RBL01523 YP_089917.1 similar to proteins from B. subtilis; RBL01522 YP_089918.1 similar to histidine permease; RBL01520 YP_089919.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_089920.1 putative cellobiose phosphotransferase system; RBL01518 YP_089921.1 putative enzyme IICB component; RBL01517 YP_089922.1 putative transcriptional regulator; RBL01516 YP_089923.1 RBL01515 YP_089924.1 putative carbonic anhydrase precursor; RBL01514 YP_089925.1 RBL01513 YP_089926.1 similar to glutaminase; catalyzes the formation of glutamate from glutamine YP_089927.1 similar to two-component sensor histidine kinase [YcbB]; RBL01509 YP_089928.1 similar to two-component response regulator [YcbA]; RBL01508 YP_089929.1 similar to ribosomal-protein-alanine N-acetyltransferase; RBL01507 YP_089930.1 RBL01506 YP_089931.1 regulatory protein blaI (Beta-lactamase repressor protein); RBL01504 YP_089932.1 beta-lactamase precursor (penicillinase); RBL01503 YP_089933.1 phosphodiesterase/alkaline phosphatase; RBL01502 YP_089934.1 putative component of the twin-arginine translocation pathway; TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_089935.1 component of the twin-arginine translocation pathway; RBL01501 YP_089936.1 similar to 5-dehydro-4-deoxyglucarate dehydratase; catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_089937.1 similar to aldehyde dehydrogenase; RBL01499 YP_089938.1 similar to glucarate transporter; RBL01498 YP_089939.1 similar to glucarate dehydratase; RBL01496 YP_089940.1 similar to transcriptional regulator (GntR family); RBL01495 YP_089941.1 RBL01494 YP_089942.1 putative two-component response regulator; RBL05885 YP_089943.1 similar to two-component response regulator [YcbM]; RBL01493 YP_089944.1 putative two-component sensor histidine kinase; RBL01492 YP_089945.1 similar to ABC transporter (ATP-binding protein); RBL01491 YP_089946.1 RBL01490 YP_089947.1 putative ABC transporter permease protein; RBL01489 YP_089948.1 RBL01488 YP_089949.1 RBL01486 YP_089950.1 similar to macrolide 2'-phosphotransferase; RBL00987 YP_089951.1 similar to transcriptional regulator (MarR family); RBL00986 YP_089952.1 RBL00985 YP_089953.1 putative serine protease; RBL00983 YP_089954.1 RBL00982 YP_089955.1 RBL00981 YP_089956.1 transcriptional activator of multidrug-efflux transporter genes; RBL00980 YP_089957.1 RBL05491 YP_089958.1 RBL05886 YP_089959.1 RBL00979 YP_089960.1 RBL05887 YP_089961.1 similar to efflux system; RBL00977 YP_089962.1 RBL00975 YP_089963.1 RBL00974 YP_089964.1 putative lantibiotic transport ATP-binding protein; RBL00972 YP_089965.1 putative protein SpaE; RBL00971 YP_089966.1 putative protein SpaG; RBL00969 YP_089967.1 putative subtilin biosynthesis regulatory protein; RBL00967 YP_089968.1 putative subtilin biosynthesis sensor protein spaK; RBL00966 YP_089969.1 similar to transcriptional regulator (LysR family); RBL00963 YP_089970.1 similar to acyloate catabolism; RBL00962 YP_089971.1 putative acyl carrier protein reductase; RBL00961 YP_089972.1 RBL00960 YP_089973.1 RBL00958 YP_089974.1 RBL00957 YP_089975.1 RBL05490 YP_089976.1 similar to proteins from B. subtilis; RBL05489 YP_089977.1 putative 6-aminohexanoate-cyclic-dimer hydrolase; RBL02559 YP_089978.1 putative cellobiose phosphotransferase system enzyme II; RBL02560 YP_089979.1 RBL04748 YP_089980.1 putative beta-lactamase protein; RBL02561 YP_089981.1 similar to glycolate oxidase subunit; RBL02562 YP_089982.1 similar to glycolate oxidase subunit; RBL02563 YP_089983.1 putative PTS system, cellobiose-specific enzyme II, B component; RBL02564 YP_089984.1 putative PTS system, cellobiose-specific enzyme II, A component; RBL02566 YP_089985.1 similar to phosphotransferase system enzyme II; RBL02567 YP_089986.1 close homolog to LicH 6-phospho-beta-glucosidase; RBL02568 YP_089987.1 similar to transcriptional regulator (GntR family); RBL02569 YP_089988.1 RBL02570 YP_089989.1 putative chitinase; RBL02571 YP_089990.1 putative chitinase; RBL02572 YP_089991.1 glutamyl endopeptidase precursor (glutamate specific endopeptidase); RBL02573 YP_089992.1 similar to glucose 1-dehydrogenase; RBL02574 YP_089993.1 RBL02575 YP_089994.1 RBL02576 YP_089995.1 putative thiosulfate sulfurtransferase protein; RBL02577 YP_089996.1 cell wall hydrolase (sporulation); RBL02578 YP_089997.1 RBL02581 YP_089998.1 similar to cell wall-binding protein; RBL02583 YP_089999.1 putative permease; RBL02584 YP_090000.1 RBL02585 YP_090001.1 putative transcriptional regulator; RBL02586 YP_090002.1 RBL02587 YP_090003.1 putative transcriptional regulator; RBL02589 YP_090004.1 putative transcriptional regulatory protein; RBL02590 YP_090005.1 similar to tellurium resistance protein; RBL02591 YP_090006.1 similar to tellurium resistance protein; RBL02592 YP_090007.1 similar to tellurium resistance protein; RBL02593 YP_090008.1 similar to tellurium resistance protein; RBL02594 YP_090009.1 putative ATP/GTP-binding protein; RBL02595 YP_090010.1 RBL04749 YP_090011.1 RBL02596 YP_090012.1 similar to toxic anion resistance protein; RBL02599 YP_090013.1 close homolog to CcdA required for a late step of cytochrome c synthesis; RBL02601 YP_090014.1 RBL02602 YP_090015.1 putative transcriptional regulator, MerR family; RBL02603 YP_090016.1 nitrate transporter; RBL02604 YP_090017.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_090018.1 L-lactate permease; RBL02607 YP_090019.1 RBL02609 YP_090020.1 similar to amino acid transporter; RBL02610 YP_090021.1 NH3-dependent NAD+ synthetase; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_090022.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_090023.1 RBL02614 YP_090024.1 similar to proline oxidase; RBL02615 YP_090025.1 similar to 1-pyrroline-5-carboxylate dehydrogenase; catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_090026.1 similar to proline permease; RBL02618 YP_090027.1 RBL02619 YP_090028.1 RBL02620 YP_090029.1 RBL02621 YP_090030.1 cephalosporin C deacetylase; RBL02622 YP_090031.1 putative transcriptional regulator, MarR family; RBL02624 YP_090032.1 RBL02625 YP_090033.1 RBL02627 YP_090034.1 similar to amino acid ABC transporter (permease); RBL02628 YP_090035.1 similar to amino acid ABC transporter (binding protein); RBL02629 YP_090036.1 putative flavodoxin; RBL02630 YP_090037.1 putative ABC-type transporter, ATPase component; RBL02632 YP_090038.1 similar to beta-glucosidase; RBL02633 YP_090039.1 RBL02634 YP_090040.1 membrane-associated nuclease; RBL04750 YP_090041.1 RBL05889 YP_090042.1 similar to protein kinase; RBL01747 YP_090043.1 putative methyl-accepting chemotaxis protein; RBL01746 YP_090044.1 methyl-accepting chemotaxis protein; RBL01745 YP_090045.1 RBL01744 YP_090046.1 putative N-methylhydantoinase A; RBL01743 YP_090047.1 putative N-methylhydantoinase B; RBL01742 YP_090048.1 putative spermidine/putrescine-binding periplasmic protein 2 precursor; RBL01741 YP_090049.1 putative multiple sugar-binding transport ATP-binding protein; RBL01740 YP_090050.1 putative spermidine/putrescine ABC transporter, permease protein; RBL01739 YP_090051.1 putative spermidineputrescine ABC transporter permease protein; RBL01738 YP_090052.1 RBL01735 YP_090053.1 RBL01731 YP_090054.1 RBL01724 YP_090055.1 RBL01723 YP_090056.1 similar to proteins from B. subtilis; RBL01722 YP_090057.1 similar to transcriptional regulator (GntR family) / aminotransferase (MocR-like); RBL01721 YP_090058.1 putative phosphopantetheinyl transferase; RBL01720 YP_090059.1 RBL01719 YP_090060.1 putative transcriptional regulator; RBL01717 YP_090061.1 similar to proteins from B. subtilis; RBL01715 YP_090062.1 RBL04838 YP_090063.1 putative ABC transporter subunit; RBL01714 YP_090064.1 RBL01713 YP_090065.1 putative 2,4-diaminobutyrate decarboxylase; RBL01712 YP_090066.1 putative methyl-accepting chemotaxis protein; RBL01711 YP_090067.1 similar to glutamine ABC transporter (ATP-binding protein); RBL01710 YP_090068.1 similar to glutamine ABC transporter (permease); RBL01708 YP_090069.1 similar to glutamine ABC transporter (glutamine-binding protein); RBL01706 YP_090070.1 transcriptional activator of arginine utilization operons; RBL00380 YP_090071.1 ornithine aminotransferase; RBL00381 YP_090072.1 amino acid permease; RBL00384 YP_090073.1 arginase; RBL00385 YP_090074.1 similar to transcriptional regulator (LysR family); RBL00386 YP_090075.1 similar to phenylacrylic acid decarboxylase; catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_090076.1 RBL00388 YP_090077.1 RBL05890 YP_090078.1 RBL00389 YP_090079.1 RBL00390 YP_090080.1 RBL00391 YP_090081.1 RBL00392 YP_090082.1 RBL00393 YP_090083.1 RBL05127 YP_090084.1 RBL00394 YP_090085.1 RBL00396 YP_090086.1 similar to proteins from B. subtilis; RBL05126 YP_090087.1 RBL05891 YP_090088.1 putative sugar ABC transporter, periplasmic sugar-binding protein; RBL00397 YP_090089.1 putative ABC transporter (permease); RBL00398 YP_090090.1 putative two-component sensor response regulator; RBL00399 YP_090091.1 putative sugar ABC transporter, periplasmic-binding protein; RBL00400 YP_090092.1 close homolog to RbsA ribose ABC transporter (ATP-binding protein); RBL00401 YP_090093.1 putative ABC transporter (permease); RBL00402 YP_090094.1 RBL00404 YP_090095.1 RBL00405 YP_090096.1 close homolog to LacA beta-galactosidase; RBL00406 YP_090097.1 phytase; RBL00407 YP_090098.1 similar to di-tripeptide ABC transporter (membrane protein); RBL05609 YP_090099.1 RBL05892 YP_090100.1 RBL00367 YP_090101.1 RBL05162 YP_090102.1 germination response to the combination of glucose, fructose, L-asparagine, and KCl; RBL00369 YP_090103.1 germination response to the combination of glucose, fructose, L-asparagine, and KCl; RBL00370 YP_090104.1 germination response to the combination of glucose, fructose, L-asparagine, and KCl; RBL00371 YP_090105.1 putative transcriptional regulator; RBL00372 YP_090106.1 similar to ABC transporter (permease); RBL00373 YP_090107.1 similar to transporter; RBL00374 YP_090108.1 similar to two-component response regulator [YclK]; RBL00375 YP_090109.1 similar to two-component sensor histidine kinase [YclJ]; RBL00376 YP_090110.1 methyl-accepting chemotaxis protein; RBL00377 YP_090111.1 similar to aspartate kinase; catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_090112.1 similar to ferrichrome ABC transporter (permease); RBL01328 YP_090113.1 similar to ferrichrome ABC transporter (permease); RBL01329 YP_090114.1 similar to ferrichrome ABC transporter (ATP-binding protein); RBL01330 YP_090115.1 similar to ferrichrome ABC transporter (binding protein); RBL01331 YP_090116.1 similar to multidrug resistance protein; RBL01332 YP_090117.1 similar to transcriptional regulator (TetR/AcrR family); RBL01333 YP_090118.1 RBL05163 YP_090119.1 similar to NADPH-flavin oxidoreductase; RBL05164 YP_090120.1 RBL05165 YP_090121.1 similar to transcriptional regulator (ArsR family); RBL05166 YP_090122.1 transcriptional activator of gabTD and repressor of gabR; RBL05893 YP_090123.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_090124.1 similar to amino acid transporter; RBL01683 YP_090125.1 succinate-semialdehyde dehydrogenase; RBL01684 YP_090126.1 RBL01685 YP_090127.1 RBL01686 YP_090128.1 RBL01687 YP_090129.1 similar to copper export protein; RBL01688 YP_090130.1 similar to transcriptional regulator (DeoR family); RBL01689 YP_090131.1 assimilatory nitrate reductase (electron transfer subunit); RBL01690 YP_090132.1 assimilatory nitrate reductase (catalytic subunit); RBL01692 YP_090133.1 assimilatory nitrite reductase (subunit); RBL01693 YP_090134.1 assimilatory nitrite reductase (subunit); RBL01694 YP_090135.1 uroporphyrin-III C-methyltransferase; RBL01695 YP_090136.1 similar to transcriptional regulator (GntR family); RBL01696 YP_090137.1 putative cotransporter; RBL00522 YP_090138.1 putative acyl-carrier-protein dehydratase; RBL05167 YP_090139.1 similar to hydroxymyristoyl-(acyl carrier protein) dehydratase; RBL05168 YP_090140.1 RBL00521 YP_090141.1 putative transcriptional regulator; RBL00520 YP_090142.1 putative sugar-specific PTS component EIIB; RBL05169 YP_090143.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_090144.1 putative transketolase; RBL00518 YP_090145.1 putative transketolase; RBL00517 YP_090146.1 similar to proteins from B. subtilis; RBL05170 YP_090147.1 similar to lactam utilization protein; RBL03221 YP_090148.1 similar to branched chain amino acids transporter; RBL03223 YP_090149.1 RBL03224 YP_090150.1 inhibitor of KinA; RBL03225 YP_090151.1 antagonist of KipI; RBL03226 YP_090152.1 transcriptional regulator of the kip operon; RBL03227 YP_090153.1 RBL03228 YP_090154.1 PTS mannitol-specific enzyme IICBA component; RBL03229 YP_090155.1 putative PTS system, mannitol-specific IIA component; RBL03231 YP_090156.1 mannitol-1-phosphate dehydrogenase; RBL03232 YP_090157.1 putative transcriptional activator of the mannitol operon; RBL03234 YP_090158.1 similar to alcohol dehydrogenase; RBL03235 YP_090159.1 RBL03236 YP_090160.1 RBL03237 YP_090161.1 similar to general stress protein; RBL03238 YP_090162.1 RBL03239 YP_090163.1 putative transcriptional regulator, LytR family; RBL03240 YP_090164.1 RBL05171 YP_090165.1 RBL03241 YP_090166.1 transcriptional regulator; RBL03242 YP_090167.1 decatenates replicating daughter chromosomes YP_090168.1 RBL02643 YP_090169.1 similar to pyruvate oxidase; catalyzes the formation of acetyl phosphate from pyruvate YP_090170.1 putative chitin binding protein; RBL02639 YP_090171.1 putative transposase; RBL05989 YP_090172.1 putative transposase; RBL06010 YP_090173.1 RBL05172 YP_090174.1 similar to acetyltransferase; RBL02637 YP_090175.1 manganese transporter; RBL02636 YP_090176.1 RBL05173 YP_090177.1 L-aspartase; catalyzes the formation of fumarate from aspartate YP_090178.1 similar to macrolide glycosyltransferase; RBL03304 YP_090179.1 RBL05175 YP_090180.1 similar to ABC transporter (binding protein); RBL03301 YP_090181.1 putative Na+/H+ antiporter; RBL03300 YP_090182.1 RBL03299 YP_090183.1 general stress protein; RBL03298 YP_090184.1 RBL03295 YP_090185.1 putative H+/glutamate symport protein; RBL03294 YP_090186.1 similar to ABC transporter (ATP-binding protein); RBL03292 YP_090187.1 similar to proteins from B. subtilis; RBL03290 YP_090188.1 RBL03289 YP_090189.1 similar to butyryl-CoA dehydrogenase; RBL03288 YP_090190.1 RBL05176 YP_090191.1 similar to thioredoxin; RBL05895 YP_090192.1 D-alanyl-D-alanine ligase A; D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_090193.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; RBL03283 YP_090194.1 putative esterase/lipase; RBL03282 YP_090195.1 similar to ATP-dependent RNA helicase; RBL03280 YP_090196.1 RBL05896 YP_090197.1 RBL03277 YP_090198.1 RBL03276 YP_090199.1 RBL03275 YP_090200.1 D-alanine racemase; RBL03274 YP_090201.1 RBL05177 YP_090202.1 RBL05178 YP_090203.1 positive regulator of sigma-B activity; RBL03271 YP_090204.1 negative regulator of sigma-B activity (antagonist of RsbT); RBL03270 YP_090205.1 positive regulator of sigma-B activity (switch protein/serine-threonine kinase); RBL03269 YP_090206.1 indirect positive regulator of sigma-B activity (serine phosphatase); RBL03268 YP_090207.1 ribosomal protein L33; RBL05179 YP_090208.1 negative regulator of sigma-B activity (switch protein/serine kinase, anti-sigma factor); binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_090209.1 RNA polymerase general stress sigma factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase YP_090210.1 indirect negative regulator of sigma-B activity (serine phosphatase); RBL03264 YP_090211.1 RBL03263 YP_090212.1 family transcriptional regulator; RBL03261 YP_090213.1 similar to transporter; RBL03260 YP_090214.1 RBL05898 YP_090215.1 putative permease; RBL01649 YP_090216.1 RBL05899 YP_090217.1 putative repressor protein; RBL05368 YP_090218.1 close homolog to Des membrane phospholipid desaturase; RBL01648 YP_090219.1 cold-shock protein; RBL05369 YP_090220.1 cold-shock protein; RBL05370 YP_090221.1 putative dehydrogenase; RBL01647 YP_090222.1 RBL01646 YP_090223.1 similar to transcriptional regulator (MarR family); RBL01645 YP_090224.1 transcriptional repressor of sporulation, septation and degradative enzyme genes; RBL04623 YP_090225.1 transcriptional repressor of sporulation and degradative enzyme genes; RBL01644 YP_090226.1 putative arginase protein; RBL01643 YP_090227.1 putative ABC transporter (ATP-binding protein); RBL05371 YP_090228.1 similar to proteins from B. subtilis; RBL01642 YP_090229.1 LysE type translocator; RBL01641 YP_090230.1 putative two-component sensor histidine kinase; RBL01640 YP_090231.1 RBL05372 YP_090232.1 putative multidrug transporter; RBL01639 YP_090233.1 RBL01638 YP_090234.1 similar to amino acid ABC transporter (permease); RBL01637 YP_090235.1 RBL01636 YP_090236.1 RBL01635 YP_090237.1 RNA polymerase ECF-type sigma factor; RBL05373 YP_090238.1 similar to anti-sigma factor; RBL05374 YP_090239.1 similar to acyltransferase; RBL00286 YP_090240.1 similar to bicyclomycin resistance protein; RBL00284 YP_090241.1 similar to two-component sensor histidine kinase; RBL00283 YP_090242.1 RBL00281 YP_090243.1 RBL00279 YP_090244.1 RBL00277 YP_090245.1 similar to sugar transporter; RBL00275 YP_090246.1 probable thiamine-monophosphate kinase; catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_090247.1 RBL00004 YP_090248.1 similar to glycoprotein endopeptidase; RBL00003 YP_090249.1 similar to ribosomal-protein-alanine N-acetyltransferase; RBL00002 YP_090250.1 probable O-sialoglycoprotein endopeptidase; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_090251.1 similar to ABC transporter (ATP-binding protein); RBL04645 YP_090252.1 similar to molybdopterin precursor biosynthesis; MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_090253.1 similar to DNA-binding protein; modulates transcription in response to the NADH/NAD(+) redox state YP_090254.1 putative component of the twin-arginine translocation pathway; TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_090255.1 component of the twin-arginine translocation pathway; RBL01208 YP_090256.1 RBL05901 YP_090257.1 RBL01207 YP_090258.1 class I heat-shock protein (chaperonin); 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_090259.1 class I heat-shock protein (chaperonin); 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_090260.1 RBL01234 YP_090261.1 RBL01233 YP_090262.1 RBL01232 YP_090263.1 RBL01231 YP_090264.1 similar to general secretion pathway protein; RBL01230 YP_090265.1 putative transcriptional regulator; RBL01229 YP_090266.1 close homolog to Pps phosphoenolpyruvate synthase; catalyzes the formation of phosphoenolpyruvate from pyruvate YP_090267.1 RBL05382 YP_090268.1 RBL01226 YP_090269.1 involved in lipoteichoic acid biosynthesis; RBL01225 YP_090270.1 para-nitrobenzyl esterase; RBL01223 YP_090271.1 putative transporter; RBL01222 YP_090272.1 phage shock protein A homolog; RBL01221 YP_090273.1 RBL01220 YP_090274.1 RBL01219 YP_090275.1 RBL01218 YP_090276.1 putative oxidoreductase protein; RBL01217 YP_090277.1 similar to cyclodextrin metabolism; RBL01216 YP_090278.1 similar to efflux protein; RBL03140 YP_090279.1 putative transcriptional regulator; RBL03141 YP_090280.1 putative required for spore cortex peptidoglycan synthesis; RBL03142 YP_090281.1 putative sporulation protein; RBL03143 YP_090282.1 RBL03144 YP_090283.1 RBL05903 YP_090284.1 RBL05904 YP_090285.1 RBL05383 YP_090286.1 similar to chitooligosaccharide deacetylase; RBL05384 YP_090287.1 converts 1,4-alpha-D-glucans to maltodextrin YP_090288.1 similar to transcriptional regulator (LacI family); RBL03371 YP_090289.1 glucan 1,4-alpha-maltohydrolase; RBL03369 YP_090290.1 similar to maltose/maltodextrin-binding protein; RBL03367 YP_090291.1 similar to maltodextrin transport system permease; RBL03366 YP_090292.1 similar to maltodextrin transport system permease; RBL03365 YP_090293.1 RBL03364 YP_090294.1 RBL03363 YP_090295.1 maltose-inducible alpha-glucosidase; RBL03361 YP_090296.1 beta-phosphoglucomutase / glucose-1-phosphate phosphodismutase; RBL03360 YP_090297.1 tyrosyl-tRNA synthetase (minor); catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_090298.1 similar to transcriptional regulator (MarR family); RBL03356 YP_090299.1 RBL03354 YP_090300.1 RBL03353 YP_090301.1 RBL03352 YP_090302.1 RBL03351 YP_090303.1 RBL03350 YP_090304.1 RBL05385 YP_090305.1 RBL04961 YP_090306.1 signal peptidase I; RBL03347 YP_090307.1 RBL05386 YP_090308.1 RBL03345 YP_090309.1 putative transcriptional regulatory protein; RBL03344 YP_090310.1 spore coat protein (outer); RBL03343 YP_090311.1 putative O-acetyl transferase; RBL03342 YP_090312.1 RBL03340 YP_090313.1 similar to cation efflux system membrane protein; RBL03339 YP_090314.1 similar to methanol dehydrogenase regulation; RBL03338 YP_090315.1 similar to proteins from B. subtilis; RBL03337 YP_090316.1 RBL03336 YP_090317.1 GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_090318.1 hypoxanthine/guanine permease; RBL04963 YP_090319.1 RBL04964 YP_090320.1 RBL05388 YP_090321.1 RBL03723 YP_090322.1 RBL04965 YP_090323.1 phosphoribosylaminoimidazole carboxylase I; Catalyzes a step in the de novo purine nucleotide biosynthetic pathway YP_090324.1 phosphoribosylaminoimidazole carboxylase II; With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_090325.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_090326.1 phosphoribosylaminoimidazole succinocarboxamide synthetase; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_090327.1 required for phosphoribosylformylglycinamidine synthetase activity; With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_090328.1 phosphoribosylformylglycinamidine synthetase I; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_090329.1 phosphoribosylformylglycinamidine synthetase II; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_090330.1 glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_090331.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_090332.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_090333.1 phosphoribosylaminoimidazole carboxy formyl formyltransferase / inosine-monophosphate cyclohydrolase; involved in de novo purine biosynthesis YP_090334.1 phosphoribosylglycinamide synthetase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_090335.1 family transcriptional regulator; RBL03739 YP_090336.1 similar to monooxygenase; RBL03740 YP_090337.1 RBL03741 YP_090338.1 putative transposase; RBL03742 YP_090339.1 RBL04967 YP_090340.1 similar to adenine deaminase; RBL04968 YP_090341.1 RBL00750 YP_090342.1 RBL00751 YP_090343.1 PcrB homolog; PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer YP_090344.1 ATP-dependent DNA helicase; RBL00754 YP_090345.1 DNA ligase (NAD-dependent); this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_090346.1 RBL00758 YP_090347.1 RBL00759 YP_090348.1 RBL04969 YP_090349.1 RBL00760 YP_090350.1 RBL00761 YP_090351.1 putative phosphotriesterase protein; RBL00762 YP_090352.1 putative phosphotriesterase protein; RBL00763 YP_090353.1 putative phosphopentomutase; catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_090354.1 RBL00766 YP_090355.1 N-acetylglucosamine-6-phosphate isomerase; RBL00767 YP_090356.1 mutant activates alkaline phosphatase during sporulation independently of sigma-F and sigma-E; RBL00769 YP_090357.1 proline transporter; RBL00770 YP_090358.1 glutamyl-tRNA(Gln) amidotransferase (subunit C); allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_090359.1 glutamyl-tRNA(Gln) amidotransferase (subunit A); allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_090360.1 glutamyl-tRNA(Gln) amidotransferase (subunit B); allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_090361.1 RBL04971 YP_090362.1 RBL04972 YP_090363.1 similar to mannan endo-1,4-beta-mannosidase; RBL00777 YP_090364.1 similar to transcriptional regulator (TetR/AcrR family); RBL00778 YP_090365.1 similar to acriflavin resistance protein; RBL00779 YP_090366.1 RBL05391 YP_090367.1 similar to ribosomal-protein-alanine N-acetyltransferase; RBL00782 YP_090368.1 RBL00784 YP_090369.1 similar to YegS from E. coli YP_090370.1 similar to RNA methyltransferase; RBL05392 YP_090371.1 putative type I restriction-modification system specificity subunit; RBL05393 YP_090372.1 putative type I restriction-modification system methylation subunit; RBL02799 YP_090373.1 putative type I restriction enzyme specificity protein; RBL02798 YP_090374.1 putative restriction enzyme type I helicase subunit; RBL02797 YP_090375.1 putative 5-methylcytosine-specific restriction enzyme A; RBL02796 YP_090376.1 close homolog to BglP PTS enzyme IIBCA component; RBL02795 YP_090377.1 close homolog to BglH beta-glucosidase; RBL02794 YP_090378.1 putative transcription antiterminator; RBL02792 YP_090379.1 response regulator aspartate phosphatase; RBL02791 YP_090380.1 RBL05905 YP_090381.1 putative methyltransferase; RBL02790 YP_090382.2 RBL02789 YP_090383.1 putative repressor protein; RBL05906 YP_090384.1 RBL02788 YP_090385.1 similar to benzaldehyde dehydrogenase; RBL02787 YP_090386.1 similar to methyl-accepting chemotaxis protein; RBL02785 YP_090387.1 putative transporter; RBL02784 YP_090388.1 similar to ABC transporter (ATP-binding protein); RBL02783 YP_090389.1 RBL05907 YP_090390.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_090391.1 putative oxidoreductase; RBL02780 YP_090392.1 RBL02778 YP_090393.1 RBL02777 YP_090394.1 6-carboxyhexanoate-CoA ligase; catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A YP_090395.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_090396.1 8-amino-7-oxononanoate synthase; RBL02773 YP_090397.1 dethiobiotin synthetase; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_090398.1 biotin synthetase; catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_090399.1 cytochrome P450 enzyme; RBL02770 YP_090400.1 putative sodium channel; RBL02768 YP_090401.1 similar to transcriptional regulator (MerR family); RBL02767 YP_090402.1 similar to multidrug-efflux transporter; RBL02766 YP_090403.1 similar to ABC transporter (ATP-binding protein); RBL02765 YP_090404.1 similar to RNA helicase; RBL02764 YP_090405.1 RBL02762 YP_090406.1 RBL02761 YP_090407.1 RBL02760 YP_090408.1 similar to 2-oxoglutarate/malate translocator; RBL05908 YP_090409.1 RBL00535 YP_090410.1 RBL00534 YP_090411.1 RBL00533 YP_090412.1 RBL00532 YP_090413.1 similar to nitric-oxide synthase; RBL00531 YP_090414.1 RBL00530 YP_090415.1 similar to transcriptional regulator (ArsR family); RBL05909 YP_090416.1 catalyzes the hydrolysis of acylphosphate YP_090417.1 RBL00528 YP_090418.1 RBL05911 YP_090419.1 RBL05912 YP_090420.1 similar to methionine aminopeptidase; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_090421.1 RBL00525 YP_090422.1 RBL00523 YP_090423.1 similar to aminoacid carrier protein; RBL04560 YP_090424.1 PTS trehalose-specific enzyme IIBC component; RBL05601 YP_090425.1 trehalose-6-phosphate hydrolase; RBL01213 YP_090426.1 transcriptional repressor of the trehalose operon; RBL01212 YP_090427.1 RBL01211 YP_090428.1 RBL02333 YP_090429.1 RBL02332 YP_090430.1 putative spore coat polysaccharide synthesis; RBL02331 YP_090431.1 putative O-acetyl transferase; RBL02330 YP_090432.1 similar to NDP-sugar epimerase; RBL02329 YP_090433.1 putative mannosyltransferase B fusion protein; RBL02328 YP_090434.1 RBL02327 YP_090435.1 putative lipopolysaccharide biosynthesis glycosyltransferase; RBL02326 YP_090436.1 spore coat polysaccharide synthesis; RBL04249 YP_090437.1 similar to dehydrogenase; RBL02325 YP_090438.1 similar to NDP-sugar dehydrogenase; RBL02324 YP_090439.1 RBL02323 YP_090440.1 similar to cinnamoyl ester hydrolase; RBL02322 YP_090441.1 similar to NAD(P)H-flavin oxidoreductase; RBL02321 YP_090442.1 similar to 2',3'-cyclic-nucleotide 2'-phosphodiesterase; in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_090443.1 RBL02318 YP_090444.1 RBL05161 YP_090445.1 putative Na(+)-linked D-alanine glycine permease; RBL02316 YP_090446.1 similar to protein-tyrosine phosphatase; RBL02315 YP_090447.1 RBL02314 YP_090448.1 RBL02313 YP_090449.1 similar to multidrug-efflux transporter; RBL02312 YP_090450.1 RBL02310 YP_090451.1 similar to H+/Ca2+ exchanger; RBL02309 YP_090452.1 RBL02308 YP_090453.1 putative thioredoxin-like oxidoreductases; RBL02306 YP_090454.1 RBL05160 YP_090455.1 similar to polysaccharide deacetylase; RBL02304 YP_090456.1 putative glycerol dehydrogenase; forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_090457.1 RBL02301 YP_090458.1 similar to divalent cation transport protein; RBL02299 YP_090459.1 similar to DNA-3-methyladenine glycosidase II; RBL02298 YP_090460.1 similar to RNA methyltransferase; RBL02297 YP_090461.1 RBL02295 YP_090462.1 RBL05914 YP_090463.1 RBL02294 YP_090464.1 RBL02293 YP_090465.1 similar to transcriptional regulator (TetR/AcrR family); RBL02292 YP_090466.1 similar to macrolide glycosyltransferase; RBL02291 YP_090467.1 RBL02289 YP_090468.1 similar to transporter; RBL01562 YP_090469.1 negative regulatory protein of SacY; RBL01561 YP_090470.1 transcriptional antiterminator involved in positive regulation of levansucrase and sucrase synthesis; RBL01560 YP_090471.1 similar to carbonic anhydrase; RBL01558 YP_090472.1 RBL01557 YP_090473.1 NADH dehydrogenase (subunit 5); Catalyzes the transfer of electrons from NADH to ubiquinone YP_090474.1 RBL01554 YP_090475.1 putative intracellular protease/amidase, ThiJ family; RBL01553 YP_090476.1 acetoin dehydrogenase E1 component (TPP-dependent alpha subunit); RBL01552 YP_090477.1 acetoin dehydrogenase E1 component (TPP-dependent beta subunit); RBL01551 YP_090478.1 acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA YP_090479.1 acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase); E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_090480.1 transcriptional activator of the acetoin dehydrogenase operon; RBL01548 YP_090481.1 RBL05159 YP_090482.1 6-phospho-alpha-glucosidase; RBL01546 YP_090483.1 RBL01545 YP_090484.1 PTS maltose-specific enzyme IICB component; RBL01544 YP_090485.1 RBL01543 YP_090486.1 RBL01542 YP_090487.1 RBL01541 YP_090488.1 RBL03424 YP_090489.1 similar to proteins from B. subtilis; RBL03425 YP_090490.1 putative 3-hydroxbutyryl-CoA dehydratase; RBL03426 YP_090491.1 xylan beta-1,4-xylosidase; RBL03427 YP_090492.1 similar to transcriptional regulator (AraC/XylS family); RBL03428 YP_090493.1 RBL03429 YP_090494.1 similar to NAD(P)H oxidoreductase; RBL03430 YP_090495.1 similar to mutator MutT protein; RBL03431 YP_090496.1 RBL03432 YP_090497.1 RBL05915 YP_090498.1 RBL05158 YP_090499.1 RBL02222 YP_090500.1 putative nitroreductase; RBL02221 YP_090501.1 RBL05157 YP_090502.1 RBL02220 YP_090503.1 similar to cell-division inhibitor; RBL02218 YP_090504.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_090505.1 RBL02215 YP_090506.1 small acid-soluble spore protein (minor); SASP K; found in the forespore compartment YP_090507.1 RBL05917 YP_090508.1 stress response protein; RBL02214 YP_090509.1 RBL02213 YP_090510.1 RBL02212 YP_090511.1 RBL02211 YP_090512.1 similar to A/G-specific adenine glycosylase; RBL02210 YP_090513.1 RBL05153 YP_090514.1 enoyl-acyl carrier protein reductase; Catalyzes a key regulatory step in fatty acid biosynthesis YP_090515.1 putative small acid-soluble spore protein; RBL05918 YP_090516.1 RBL05151 YP_090517.1 RBL02208 YP_090518.1 similar to ABC transporter (ATP-binding protein); RBL02207 YP_090519.1 putative oligopeptide ABC transporter (ATP-binding protein); RBL02206 YP_090520.1 putative oligopeptid ABC transporter; RBL02205 YP_090521.1 putative oligopeptide ABC transporter (binding protein) (initiation of sporulation, competence development); RBL02204 YP_090522.1 putative oligopeptide ABC transporter (permease); RBL02203 YP_090523.1 putative oligopeptide ABC transporter; RBL02202 YP_090524.1 RBL02201 YP_090525.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_090526.1 similar to bacterioferritin comigratory protein; RBL05920 YP_090527.1 transcriptional repressor of the peroxide regulon; RBL05921 YP_090528.1 RBL05922 YP_090529.1 similar to proteins from B. subtilis; RBL05923 YP_090530.1 putative response regulator aspartate phosphatase rapD; RBL05924 YP_090531.1 RBL05925 YP_090532.1 RBL05926 YP_090533.1 RBL05927 YP_090534.1 RBL03138 YP_090535.1 RBL05488 YP_090536.1 RBL03139 YP_090537.1 RBL05009 YP_090538.1 RBL05113 YP_090539.1 response regulator aspartate phosphatase; RBL00801 YP_090540.1 RBL00799 YP_090541.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_090542.1 biosynthesis of the pyrimidine moiety of thiamin; required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_090543.1 aliphatic sulfonate ABC transporter (binding protein); RBL00795 YP_090544.1 aliphatic sulfonate ABC transporter (binding lipoprotein); RBL00794 YP_090545.1 aliphatic sulfonate ABC transporter (permease); RBL00792 YP_090546.1 aliphatic sulfonate monooxygenase; catalyzes the release of sulfite from alkanesulfonates YP_090547.1 RBL00790 YP_090548.1 RBL05008 YP_090549.1 RBL05486 YP_090550.1 putative ABC transporter (ATP-binding protein); RBL00789 YP_090551.1 RBL00788 YP_090552.1 RBL00787 YP_090553.1 RBL05007 YP_090554.1 similar to ribosomal protein S14; located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_090555.1 RBL03796 YP_090556.1 RBL03795 YP_090557.1 RBL03794 YP_090558.1 rRNA methylase homolog; RBL03793 YP_090559.1 similar to proteins from B. subtilis; RBL03792 YP_090560.1 similar to proteins from B. subtilis; RBL03791 YP_090561.1 similar to proteins from B. subtilis; RBL03790 YP_090563.1 serine protein kinase; RBL03789 YP_090564.1 RBL03786 YP_090565.1 RBL03785 YP_090566.1 similar to multidrug resistance protein; RBL03784 YP_090567.1 similar to trp repressor binding protein; RBL03783 YP_090568.1 RBL03782 YP_090569.1 putative glycine betaine/L-proline transport; RBL05484 YP_090570.1 similar to ABC transporter (ATP-binding protein); RBL03781 YP_090571.1 RBL03780 YP_090572.1 major cold-shock protein; RBL05004 YP_090573.1 putative ABC transporter ATP-binding protein; RBL05003 YP_090574.1 putative ABC transporter permease protein; RBL05002 YP_090575.1 similar to ABC transporter (binding lipoprotein); RBL05001 YP_090576.1 similar to sodium-glutamate symporter; RBL03334 YP_090577.1 RBL03332 YP_090578.1 putative acylamino-acid-releasing enzyme; RBL03331 YP_090579.1 RBL05000 YP_090580.1 RBL03329 YP_090581.1 similar to proteins from B. subtilis; RBL03328 YP_090582.1 putative two-component hybrid sensor and regulator; RBL03327 YP_090583.1 similar to 5'-nucleotidase; RBL03326 YP_090584.1 RBL03325 YP_090585.1 RBL03324 YP_090586.1 RBL03323 YP_090587.1 similar to IMP dehydrogenase; RBL03322 YP_090588.1 similar to phosphoglycolate phosphatase; RBL03321 YP_090589.1 RBL03320 YP_090590.1 putative transporter; RBL03318 YP_090591.1 similar to formate transporter; RBL03317 YP_090592.1 putative permease; RBL03315 YP_090593.1 similar to alcohol dehydrogenase; RBL03314 YP_090594.1 transcriptional antiterminator and control of mRNA stability of glpD; RBL05687 YP_090595.1 glycerol uptake facilitator; RBL05686 YP_090596.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_090597.1 glycerol-3-phosphate dehydrogenase; RBL02884 YP_090598.1 similar to phosphomannomutase; RBL02883 YP_090599.1 RBL02880 YP_090600.1 putative transcriptional repressor, putative; RBL05049 YP_090601.1 similar to two-component sensor histidine kinase [YhcZ]; RBL02879 YP_090602.1 similar to two-component response regulator [YhcY]; RBL02878 YP_090603.1 similar to azoreductase; RBL02877 YP_090604.1 RBL02876 YP_090605.1 RBL02875 YP_090606.1 RBL02874 YP_090607.1 flavohemoglobin; RBL02873 YP_090608.1 involved in spore cortex synthesis; RBL02872 YP_090609.1 cell wall hydrolase (major autolysin); RBL02871 YP_090610.1 transcriptional repressor of the citrate synthase I gene; RBL02870 YP_090611.1 citrate synthase I (minor); RBL02869 YP_090612.1 putative oxidoreductase; RBL02868 YP_090613.1 similar to glucose 1-dehydrogenase; RBL02867 YP_090614.1 similar to sodium-dependent transporter; RBL02865 YP_090615.1 putative pyridoxalphosphat-dependent decarboxylase; RBL02864 YP_090616.1 similar to transcriptional regulator (AraC/XylS family); RBL02863 YP_090617.1 similar to transcriptional regulator (GntR family) / aminotransferase (MocR-like); RBL02862 YP_090618.1 RBL02861 YP_090619.1 RBL05048 YP_090620.1 RBL02860 YP_090621.1 RNA polymerase ECF-type sigma factor; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress YP_090622.1 RBL05047 YP_090623.1 similar to 1-acylglycerol-3-phosphate O-acyltransferase; RBL00678 YP_090624.1 RBL00679 YP_090625.1 putative acyl-CoA thioesterase; RBL00680 YP_090626.1 putative transcriptional regulator, AcrR family; RBL00681 YP_090627.1 similar to hemolysin; RBL00683 YP_090628.1 similar to transcriptional regulator (MerR family); RBL00684 YP_090629.1 similar to hemolysin; RBL00685 YP_090630.1 RBL00687 YP_090631.1 RBL05933 YP_090632.1 putative N-acetylmuramoyl-L-alanine amidase; RBL00689 YP_090633.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_090634.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_090635.1 similar to glycerophosphodiester phosphodiesterase; RBL00693 YP_090636.1 RBL05934 YP_090637.1 RBL00694 YP_090638.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_090639.1 putative acetyltransferase; RBL00696 YP_090640.1 similar to endo-1,4-beta-xylanase; RBL00698 YP_090641.1 probable D-alanine aminotransferase; RBL00699 YP_090642.1 Na+/H+ antiporter; RBL00700 YP_090643.1 similar to proteins from B. subtilis; RBL00701 YP_090644.1 RBL00702 YP_090645.1 RBL00704 YP_090646.1 RBL00706 YP_090647.1 putative regulatory gene for nhaC; RBL00709 YP_090648.1 similar to ABC transporter (ATP-binding protein); RBL00710 YP_090649.1 similar to ABC transporter (ATP-binding protein); RBL00711 YP_090650.1 similar to calcium-binding protein; RBL00712 YP_090651.1 small acid-soluble spore protein (major beta-type SASP); RBL05046 YP_090652.1 RBL00713 YP_090653.1 multiple sugar-binding transport ATP-binding protein; RBL00715 YP_090654.1 RBL00716 YP_090655.1 RBL05598 YP_090656.1 similar to proteins from B. subtilis; RBL00717 YP_090657.1 similar to proteins from B. subtilis; RBL00718 YP_090658.1 RBL00719 YP_090659.1 RBL00720 YP_090660.1 RBL05597 YP_090661.1 RBL04193 YP_090662.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_090663.1 similar to enoyl CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_090664.1 putative response regulator aspartate phosphatase A; RBL01911 YP_090665.1 RBL05596 YP_090666.1 RBL05595 YP_090667.1 similar to ABC transporter (ATP-binding protein); RBL01910 YP_090668.1 RBL01909 YP_090669.1 RBL01908 YP_090670.1 RBL01907 YP_090671.1 similar to CMP-binding factor; catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_090672.1 RBL05594 YP_090673.1 protein secretion (post-translocation molecular chaperone); RBL04186 YP_090675.1 RBL05592 YP_090676.1 RBL05591 YP_090677.1 RBL04185 YP_090678.1 RBL04184 YP_090679.1 transcriptional repressor of sporulation and extracellular proteases genes; hpr; ScoC; MarR family; protease production regulatory protein YP_090680.1 similar to proteins from B. subtilis; RBL04182 YP_090681.1 RBL05590 YP_090682.1 RBL04181 YP_090683.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_090684.1 Hit-like protein involved in cell-cycle regulation; RBL00111 YP_090685.1 RBL00110 YP_090686.1 ABC transporter (ATP-binding protein); RBL00109 YP_090687.1 ABC transporter (membrane protein); RBL00108 YP_090688.1 function; RBL00106 YP_090689.1 similar to aminoacylase; RBL00104 YP_090690.1 RBL00101 YP_090691.1 similar to proteins from B. subtilis; RBL00100 YP_090692.1 penicillin-binding protein 2C; RBL00099 YP_090693.1 uroporphyrinogen III decarboxylase; catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_090694.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_090695.1 protoporphyrinogen IX and coproporphyrinogen III oxidase; catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_090696.1 similar to transcriptional regulator (TetR/AcrR family); RBL00095 YP_090697.1 similar to phage infection protein; RBL00094 YP_090698.1 beta-ketoacyl-acyl carrier protein synthase III; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_090699.1 similar to glucanase; RBL00092 YP_090700.1 spore coat protein; RBL05589 YP_090701.1 H+/Na+-glutamate symport; RBL00091 YP_090702.1 RBL00090 YP_090703.1 similar to lipoate-protein ligase; RBL00089 YP_090704.1 similar to long-chain fatty-acid-CoA ligase; activates fatty acids by binding to coenzyme A YP_090705.1 RBL05935 YP_090706.1 putative DNA-binding protein; RBL00952 YP_090707.1 putative amino acid transporter; RBL00953 YP_090708.1 putative permease; RBL00954 YP_090709.1 RBL00955 YP_090710.1 RBL00956 YP_090711.1 RBL04913 YP_090712.1 similar to iron(III) dicitrate-binding protein; RBL03951 YP_090713.1 similar to ferrichrome ABC transporter (permease); RBL03949 YP_090714.1 similar to ferrichrome ABC transporter (permease); RBL03948 YP_090715.1 similar to 2,3-diphosphoglycerate-dependent phosphoglycerate mutase; RBL03947 YP_090716.1 haem-based aerotactic transducer; RBL03946 YP_090717.1 similar to Rieske [2Fe-2S] iron-sulfur protein; RBL03945 YP_090718.1 similar to alcohol dehydrogenase; RBL03941 YP_090719.1 RBL04912 YP_090720.1 competence transcription factor (CTF); RBL04910 YP_090721.1 RBL04911 YP_090722.1 similar to proteins from B. subtilis; RBL03091 YP_090723.1 signal peptidase I; RBL03089 YP_090724.1 minor extracellular serine protease; RBL03088 YP_090725.1 putative metabolite transport protein; RBL03087 YP_090726.1 putative transcriptional regulator, pucR; RBL03086 YP_090727.1 Plays a crucial role on both purine and pyrimidine metabolism YP_090728.1 putative permease; allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_090729.1 RBL03083 YP_090730.1 putative ureidoglycolate dehydrogenase; RBL03082 YP_090731.1 similar to malate dehydrogenase; RBL03081 YP_090732.1 multicopy suppressor of dominant negative ftsH mutations YP_090733.1 RBL03079 YP_090734.1 RBL03078 YP_090735.1 putative carbamate kinase; catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_090736.1 putative metabolite transport protein; RBL03076 YP_090737.1 RBL03075 YP_090738.1 response regulator aspartate phosphatase; RBL03074 YP_090739.1 RBL05585 YP_090740.1 transcriptional regulator; RBL03071 YP_090741.1 multiple sugar-binding protein; RBL03070 YP_090742.1 sugar transport; RBL03069 YP_090743.1 maltose transport protein; RBL03068 YP_090744.1 alpha-D-galactoside galactohydrolase; RBL03067 YP_090745.1 RBL03065 YP_090746.1 polypeptide composition of the spore coat; RBL04908 YP_090747.1 polypeptide composition of the spore coat; RBL04907 YP_090748.1 polypeptide composition of the spore coat; RBL03063 YP_090749.1 putative malate dehydrogenase; activates fatty acids by binding to coenzyme A YP_090750.1 similar to multidrug-efflux transporter; RBL03061 YP_090751.1 RBL03058 YP_090752.1 putative two-component sensor histidine kinase; RBL03057 YP_090753.1 putative two-component response regulator; RBL03056 YP_090754.1 RBL03055 YP_090755.1 similar to molybdate-binding protein; RBL03054 YP_090756.1 similar to molybdenum transport permease; RBL03053 YP_090757.1 ATP-dependent deoxyribonuclease (subunit B); RBL03051 YP_090758.1 ATP-dependent deoxyribonuclease (subunit A); RBL03050 YP_090759.1 exonuclease SbcD homolog; RBL03047 YP_090760.1 similar to DNA exonuclease; RBL03044 YP_090761.1 probable spore germination protein; RBL04906 YP_090762.1 probable spore germination protein; RBL03041 YP_090763.1 probable spore germination protein; RBL05936 YP_090764.1 probable spore germination protein; RBL03040 YP_090765.1 probable spore germination protein; RBL04905 YP_090766.1 probable spore germination protein; RBL04904 YP_090767.1 RBL04903 YP_090768.1 RBL05584 YP_090769.1 spore coat protein (inner); RBL03039 YP_090770.1 RBL03038 YP_090771.1 similar to 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase; RBL03037 YP_090772.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_090773.1 RBL03256 YP_090774.1 similar to proteins from B. subtilis; RBL03255 YP_090775.1 asparagine synthetase; RBL03254 YP_090776.1 putative ammonium transporter; RBL03253 YP_090777.1 putative nitrogen regulatory protein P-II; RBL04902 YP_090778.1 RBL04901 YP_090779.1 similar to transcriptional regulator (AraC/XylS family); RBL04900 YP_090780.1 similar to phage-related protein; RBL04899 YP_090781.1 transcriptional activator involved in the degradation of glutamine phosphoribosylpyrophosphate amidotransferase; RBL04898 YP_090782.1 similar to myo-inositol 2-dehydrogenase; RBL00516 YP_090783.1 similar to transcriptional regulator (GntR family) / aminotransferase (MocR-like); RBL00515 YP_090784.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_090785.1 putative-2,4-diaminobutyrate decarboxylase; RBL00512 YP_090786.1 putative siderophore biosynthesis protein IucA; RBL00511 YP_090787.1 putative siderophore biosynthesis protein IucB; RBL00510 YP_090788.1 putative siderophore biosynthesis protein IucD; RBL00509 YP_090789.1 putative siderophore biosynthesis protein IucC; RBL00508 YP_090790.1 RBL00507 YP_090791.1 putative oxidoreductase; RBL00506 YP_090792.1 putative transcriptional regulator; RBL00505 YP_090793.1 putative 5-methyltetrahydrofolate-homocysteine methyltransferase; RBL00504 YP_090794.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_090795.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_090796.1 RBL05937 YP_090797.1 RBL05938 YP_090798.1 RBL05939 YP_090799.1 RBL05940 YP_090800.1 intracellular proteinase inhibitor; RBL05941 YP_090801.1 GMP reductase; RBL05942 YP_090802.1 RBL05943 YP_090803.1 RBL05944 YP_090804.1 RBL05945 YP_090805.1 RBL05946 YP_090806.1 RBL05947 YP_090807.1 N-acetylglutamate gamma-semialdehyde dehydrogenase; catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_090808.1 ornithine acetyltransferase / amino-acid acetyltransferase; bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_090809.1 N-acetylglutamate 5-phosphotransferase; catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_090810.1 N-acetylornithine aminotransferase; RBL01368 YP_090811.1 carbamoyl-phosphate transferase-arginine (subunit A); catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_090812.1 carbamoyl-phosphate transferase-arginine (subunit B); four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_090813.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_090814.1 putative undecaprenol kinase; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell YP_090815.1 RBL05948 YP_090816.1 RBL05949 YP_090817.1 RBL04554 YP_090818.1 similar to UDP-glucose 4-epimerase; RBL04556 YP_090819.1 positive regulator of comK; RBL05125 YP_090820.1 late competence gene; RBL05124 YP_090821.1 RBL05123 YP_090822.1 beta-ketoacyl-acyl carrier protein synthase III; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_090823.1 beta-ketoacyl-acyl carrier protein synthase II; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_090824.1 RBL00626 YP_090825.1 oligopeptide ABC transporter (ATP-binding protein); RBL00625 YP_090826.1 oligopeptide ABC transporter (ATP-binding protein); RBL00624 YP_090827.1 oligopeptide ABC transporter (oligopeptide-binding protein); RBL00623 YP_090828.1 oligopeptide ABC transporter (permease); RBL00622 YP_090829.1 oligopeptide ABC transporter (permease); RBL00621 YP_090830.1 putative efflux protein; RBL00619 YP_090831.1 RBL00617 YP_090832.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_090833.1 oligopeptide ABC transporter (binding protein) (initiation of sporulation, competence development); RBL00614 YP_090834.1 oligopeptide ABC transporter (permease) (initiation of sporulation, competence development); RBL00613 YP_090835.1 oligopeptide ABC transporter (permease) (initiation of sporulation, competence development); RBL00612 YP_090836.1 oligopeptide ABC transporter (ATP-binding protein) (initiation of sporulation, competence development); RBL00611 YP_090837.1 oligopeptide ABC transporter (ATP-binding protein) (initiation of sporulation, competence development); RBL00610 YP_090838.1 RBL00609 YP_090839.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_090840.1 negative regulator of competence; enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_090841.1 RBL00604 YP_090842.1 RBL00603 YP_090843.1 RBL00602 YP_090844.1 putative two-component response regulator involved in the response to the environmental Mg-citrate complex; RBL00601 YP_090845.1 putative sensor kinase; RBL00600 YP_090846.1 RBL00598 YP_090847.1 similar to oligoendopeptidase; RBL00597 YP_090848.1 RBL04796 YP_090849.1 RBL00595 YP_090850.1 RBL00593 YP_090851.1 similar to lytic transglycosylase; RBL00592 YP_090852.1 RBL00591 YP_090853.1 RBL00590 YP_090854.1 similar to GTP pyrophosphokinase; RBL00589 YP_090855.1 catalyzes the phosphorylation of NAD to NADP YP_090856.1 RBL00586 YP_090857.1 similar to diadenosine tetraphosphatase; asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate YP_090858.1 similar to Na+/H+ antiporter; RBL00584 YP_090859.1 transcriptional regulator of extracellular enzyme genes; RBL00583 YP_090860.1 transcriptional activator of extracellular enzyme genes; regulates the production of extracellular enzymes YP_090861.1 glycine oxidase; RBL00581 YP_090862.1 hydroxyethylthiazole phosphate biosynthesis; RBL04795 YP_090863.1 hydroxyethylthiazole phosphate biosynthesis; functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_090864.1 hydroxyethylthiazole phosphate biosynthesis; catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_090865.1 similar to phosphomethylpyrimidine kinase; catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_090866.1 enoyl-acyl carrier protein reductase; Catalyzes a key regulatory step in fatty acid biosynthesis YP_090867.1 RBL04794 YP_090868.1 spore coat protein (insoluble fraction); RBL00573 YP_090869.1 spore coat protein (insoluble fraction); RBL00572 YP_090870.1 spore coat protein (insoluble fraction); RBL04793 YP_090871.1 RBL00570 YP_090872.1 spore coat protein (insoluble fraction); RBL00569 YP_090873.1 RBL00567 YP_090874.1 RBL04792 YP_090875.1 RBL04791 YP_090876.1 similar to ATP-dependent DNA helicase; RBL00565 YP_090877.1 RBL00563 YP_090878.1 similar to alkaline phosphatase; RBL00562 YP_090879.1 putative UDP-glucose 4-epimerase; RBL00561 YP_090880.1 similar to UTP-glucose-1-phosphate uridylyltransferase; RBL00560 YP_090881.1 RBL00559 YP_090882.1 RBL00557 YP_090883.1 similar to 2'-5' RNA ligase YP_090884.1 RBL00555 YP_090885.1 RBL00554 YP_090886.1 RBL00553 YP_090887.1 putative repressor transcription regulator protein; RBL00552 YP_090888.1 similar to cystathionine gamma-synthase; catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity YP_090889.1 similar to cystathionine beta-lyase; catalyzes the formation of L-homocysteine from cystathionine YP_090890.1 RBL00549 YP_090891.1 putative transcriptional regulator, MarR/EmrR family; RBL00548 YP_090892.1 RBL00547 YP_090893.1 penicillin-binding protein 4* (spore cortex); RBL00546 YP_090894.1 arabinan-endo 1,5-alpha-L-arabinase; RBL00545 YP_090895.1 RBL05121 YP_090896.1 probable maltose O-acetyltransferase; RBL00544 YP_090897.1 RBL04790 YP_090898.1 similar to transcriptional regulator (LysR family); RBL00543 YP_090899.1 similar to sulfite reductase; RBL00542 YP_090900.1 similar to sulfite reductase; hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_090901.1 similar to transcriptional regulator (LysR family); RBL00540 YP_090902.1 similar to transcriptional regulator (LysR family); RBL00539 YP_090903.1 RBL00538 YP_090904.1 RBL00537 YP_090905.1 RBL00536 YP_090906.1 putative cell wall-binding protein; RBL02468 YP_090907.1 close homolog to LmrB lincomycin-resistance protein; RBL02467 YP_090908.1 similar to transcriptional regulator; RBL02465 YP_090909.1 RBL02464 YP_090910.1 RBL05267 YP_090911.1 RBL02462 YP_090912.1 similar to proteins from B. subtilis; RBL02461 YP_090913.1 similar to phage-related replication protein; RBL02460 YP_090914.1 PBSX prophage; RBL02458 YP_090915.1 transcriptional repressor of PBSX genes; RBL02457 YP_090916.1 putative repressor protein; RBL04937 YP_090917.1 RBL04936 YP_090918.1 PBSX prophage; RBL04935 YP_090919.1 PBSX prophage; RBL02455 YP_090920.1 RBL05951 YP_090921.1 PBSX prophage; RBL02453 YP_090922.1 PBSX prophage; RBL04934 YP_090923.1 RNA polymerase PBSX sigma factor-like; Positive regulatory protein that acts at the late promoter PL YP_090924.1 PBSX terminase (small subunit); RBL02451 YP_090925.1 PBSX terminase (large subunit); RBL02450 YP_090926.1 PBSX prophage; RBL02449 YP_090927.1 PBSX prophage; RBL02448 YP_090928.1 PBSX prophage; RBL02447 YP_090929.1 RBL05264 YP_090930.1 similar to phage-related protein; RBL02444 YP_090931.1 PBSX prophage; RBL02443 YP_090932.1 PBSX prophage; RBL02442 YP_090933.1 RBL04933 YP_090934.1 PBSX prophage; RBL02440 YP_090935.1 PBSX prophage; RBL02437 YP_090936.1 PBSX prophage; RBL02436 YP_090937.1 PBSX prophage; RBL04932 YP_090938.1 PBSX prophage; RBL02435 YP_090939.1 PBSX prophage; RBL02433 YP_090940.1 similar to phage-related protein; RBL02432 YP_090941.1 putative phage PBSX protein; RBL02431 YP_090942.1 PBSX prophage; RBL02430 YP_090943.1 similar to phage-related protein; RBL02429 YP_090944.1 PBSX prophage; RBL02428 YP_090945.1 RBL05263 YP_090946.1 putative phage PBSX protein; RBL02425 YP_090947.1 putative phage PBSX protein; RBL02424 YP_090948.1 involved in cell lysis upon induction of PBSX; RBL04931 YP_090949.1 putative cell wall hydrolase; RBL04930 YP_090950.1 close homolog to BlyA N-acetylmuramoyl-L-alanine amidase; RBL02423 YP_090951.1 putative transcriptional regulator, GntR family; RBL02421 YP_090952.1 similar to alcohol dehydrogenase; RBL02420 YP_090953.1 D-mannonate hydrolase; catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_090954.1 similar to D-mannonate oxidoreductase; Converts D-mannonate to D-mannuronate YP_090955.1 putative dehydrogenase; RBL02417 YP_090956.1 hexuronate transporter; RBL02416 YP_090957.1 disruption blocks sporulation after septum formation; RBL05262 YP_090958.1 lethal when synthesized during vegetative growth in the absence of SpoIISB; RBL02415 YP_090959.1 probable low-affinity inorganic phosphate transporter; RBL02414 YP_090960.1 RBL02413 YP_090961.1 gamma-glutamyltranspeptidase; RBL02412 YP_090962.1 similar to proteins from B. subtilis; RBL02410 YP_090963.1 similar to two-component sensor histidine kinase [YesN]; RBL02409 YP_090964.1 similar to two-component response regulator [YesM]; RBL02408 YP_090965.1 similar to sugar-binding protein; RBL02407 YP_090966.1 similar to lactose permease; RBL02406 YP_090967.1 similar to lactose permease; RBL02405 YP_090968.1 RBL02404 YP_090969.1 similar to transcriptional regulator (AraC/XylS family); RBL02402 YP_090970.1 similar to rhamnogalacturonan acetylesterase; RBL02401 YP_090971.1 RBL02400 YP_090972.1 RBL02399 YP_090973.1 similar to proteins from B. subtilis; RBL02398 YP_090974.1 RBL05952 YP_090975.1 RBL02395 YP_090976.1 similar to proteins from B. subtilis; RBL02394 YP_090977.1 similar to ion channel; RBL02392 YP_090978.1 similar to rhamnogalacturonan acetylesterase; RBL02391 YP_090979.1 similar to beta-galactosidase; RBL02390 YP_090980.1 RBL02389 YP_090981.1 lipoprotein; RBL02387 YP_090982.1 transmembrane lipoprotein; RBL02385 YP_090983.1 transmembrane lipoprotein; RBL02384 YP_090984.1 similar to amino acid permease; RBL02383 YP_090985.1 RBL05261 YP_090986.1 RBL00646 YP_090987.1 serine protease Do (heat-shock protein); RBL00645 YP_090988.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_090989.1 D-alanyl-aminopeptidase; RBL00641 YP_090990.1 dipeptide ABC transporter (permease) (sporulation); RBL00639 YP_090991.1 dipeptide ABC transporter (permease) (sporulation); RBL00638 YP_090992.1 dipeptide ABC transporter (ATP-binding protein) (sporulation); RBL00637 YP_090993.1 dipeptide ABC transporter (dipeptide-binding protein) (sporulation); RBL00635 YP_090994.1 similar to immunity to bacteriotoxins; RBL00634 YP_090995.1 similar to chloromuconate cycloisomerase; RBL05681 YP_090996.1 similar to polysugar degrading enzyme; RBL00630 YP_090997.1 similar to oligopeptide ABC transporter (permease); RBL00629 YP_090998.1 RBL00628 YP_090999.1 similar to acyl-CoA hydrolase; RBL05260 YP_091000.1 similar to proteins from B. subtilis; RBL05680 YP_091001.1 pectate lyase; RBL00830 YP_091002.1 RBL00829 YP_091003.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_091004.1 RBL00827 YP_091005.1 RBL00826 YP_091006.1 similar to molecular chaperone; RBL00825 YP_091007.1 similar to molecular chaperone; RBL05259 YP_091008.1 similar to formyltetrahydrofolate deformylase; produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_091009.1 glutamate 5-kinase; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_091010.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_091011.1 RBL00819 YP_091012.1 RBL00818 YP_091013.1 similar to organic hydroperoxide resistance protein; RBL05953 YP_091014.1 RBL00815 YP_091015.1 guanine deaminase; RBL05258 YP_091016.1 putative phosphoglycerate mutase; RBL00812 YP_091017.1 RBL00811 YP_091018.1 RBL00810 YP_091019.1 cobalamin-independent methionine synthase; catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_091020.1 major intracellular serine protease; RBL00808 YP_091021.1 similar to proteins from B. subtilis; RBL05954 YP_091022.1 similar to Mg2+ transporter; RBL05955 YP_091023.1 RBL00736 YP_091024.1 putative integrase-phage associated; RBL00737 YP_091025.1 similar to phage-related protein; RBL05461 YP_091026.1 RBL05460 YP_091027.1 RBL05459 YP_091028.1 RBL05458 YP_091029.1 similar to transcriptional regulator (phage-related) (Xre family); RBL05457 YP_091030.1 RBL05456 YP_091031.1 RBL05956 YP_091032.1 RBL01327 YP_091033.1 RBL05455 YP_091034.1 RBL05454 YP_091035.1 RBL05453 YP_091036.1 similar to phage-related protein; RBL01325 YP_091037.1 similar to phage-related protein; RBL01324 YP_091038.1 RBL05957 YP_091039.1 similar to phage-related protein; RBL01323 YP_091040.1 similar to phage-related protein; RBL05452 YP_091041.1 RBL05451 YP_091042.1 RBL05450 YP_091043.1 RBL05958 YP_091044.1 RBL05959 YP_091045.1 RBL05449 YP_091046.1 RBL05960 YP_091047.1 RBL05961 YP_091048.1 RBL01319 YP_091049.1 putative single-stranded DNA-binding protein; RBL05962 YP_091050.1 RBL05446 YP_091051.1 RBL05445 YP_091052.1 RBL01316 YP_091053.1 RBL05963 YP_091054.1 similar to proteins from B. subtilis; RBL05442 YP_091055.1 RBL05964 YP_091056.1 RBL05441 YP_091057.1 similar to phage-related terminase small subunit; RBL01313 YP_091058.1 putative multidrug resistance protein; RBL01312 YP_091059.1 putative portal protein; RBL01311 YP_091060.1 RBL01310 YP_091061.1 RBL05440 YP_091062.1 RBL01307 YP_091063.1 RBL01306 YP_091064.1 putative phage capsid protein; RBL01305 YP_091065.1 RBL01304 YP_091066.1 RBL05965 YP_091067.1 RBL05966 YP_091068.1 RBL05967 YP_091069.1 RBL01301 YP_091070.1 putative phage tail protein; RBL05439 YP_091071.1 putative phage tail protein; RBL05438 YP_091072.1 RBL01300 YP_091073.1 RBL05437 YP_091074.1 RBL01298 YP_091075.1 RBL01295 YP_091076.1 RBL01294 YP_091077.1 RBL05436 YP_091078.1 RBL05435 YP_091079.1 hydrolysis of 5-bromo 4-chloroindolyl phosphate upon induction of PBSX; RBL05434 YP_091080.1 putative glycosyl hydrolase/lysozyme; RBL03712 YP_091081.1 RBL03711 YP_091082.1 RBL03710 YP_091083.1 RBL03709 YP_091084.1 transcriptional pleiotropic regulator invoved in global nitrogen regulation; RBL03708 YP_091085.1 RBL05433 YP_091086.1 RBL05083 YP_091087.1 similar to transcriptional regulator (MarR family); RBL03707 YP_091088.1 similar to ATP-dependent DNA ligase; catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_091089.1 RBL03704 YP_091090.1 RBL03703 YP_091091.1 similar to alkaline phosphatase; RBL03702 YP_091092.1 similar to toxic anion resistance protein; RBL03701 YP_091093.1 RNA polymerase sigma factor; Heat shock-induced YP_091094.1 RBL03699 YP_091095.1 small acid-soluble spore protein (minor alpha/beta-type SASP); RBL05082 YP_091096.1 RBL03697 YP_091097.1 similar to heat-shock protein; putative metalloprotease YP_091098.1 similar to Na+-transporting ATP synthase; RBL03856 YP_091099.1 penicillin-binding protein 3; RBL03855 YP_091100.1 RBL05432 YP_091101.1 RBL05969 YP_091102.1 RBL03853 YP_091103.1 two-component sensor histidine kinase involved in the initiation of sporulation; RBL03852 YP_091104.1 O6-methylguanine DNA alkyltransferase; RBL03851 YP_091105.1 similar to initiation factor eIF-2B (alpha subunit); isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_091106.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_091107.1 RBL03847 YP_091108.1 similar to aspartate aminotransferase; produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however YP_091109.1 similar to ribulose-bisphosphate carboxylase; converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage YP_091110.1 RBL03843 YP_091111.1 RBL03842 YP_091112.1 similar to fosfomycin resistance protein; catalyzes resistance to fosfomycin by the addition of a thiol cofactor YP_091113.1 RBL05079 YP_091114.1 negative sporulation regulatory phosphatase; RBL05970 YP_091115.1 two-component sensor histidine kinase involved in the initiation of sporulation; RBL05078 YP_091116.1 similar to transcriptional regulator (MarR family); RBL03958 YP_091117.1 motility protein (flagellar motor rotation); with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_091118.1 motility protein (flagellar motor rotation); With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_091119.1 ATP-dependent Clp protease-like (class III stress gene); RBL03964 YP_091120.1 similar to proteins from B. subtilis; RBL05077 YP_091121.1 similar to aluminum resistance protein; RBL01154 YP_091122.1 similar to 6-pyruvoyl tetrahydrobiopterin synthase; RBL01155 YP_091123.1 similar to coenzyme PQQ synthesis; RBL01156 YP_091124.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_091125.1 putative integrase/recombinase; RBL01158 YP_091126.1 RBL01159 YP_091127.1 RBL05431 YP_091128.1 RBL05971 YP_091129.1 RBL05076 YP_091130.1 RBL05430 YP_091131.1 RBL05074 YP_091132.1 DNA ligase (ATP-dependent); catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_091133.1 RBL01163 YP_091134.1 RBL05972 YP_091135.1 RBL05427 YP_091136.1 RBL05073 YP_091137.1 RBL05072 YP_091138.1 RBL05425 YP_091139.1 RBL01164 YP_091140.1 putative terminase-small subunit; RBL05973 YP_091141.1 putative terminase; RBL01166 YP_091142.1 putative phage head portal protein; RBL01167 YP_091143.1 putative phage pi3 protein 23, ATP dependent Clp protease; RBL01168 YP_091144.1 RBL01169 YP_091145.1 RBL05070 YP_091146.1 RBL05974 YP_091147.1 RBL01171 YP_091148.1 RBL05068 YP_091149.1 putative phage tail protein; RBL01172 YP_091150.1 RBL05067 YP_091151.1 RBL05066 YP_091152.1 similar to phage-related protein; RBL01173 YP_091153.1 RBL01174 YP_091154.1 RBL01175 YP_091155.1 RBL01176 YP_091156.1 prophage ORF xkdV; RBL01177 YP_091157.1 RBL05422 YP_091158.1 similar to phage-related protein; RBL05975 YP_091159.1 putative phosphodiesterase; RBL01178 YP_091160.1 holin-like protein; RBL05421 YP_091161.1 N-acetylmuramoyl-L-alanine amidase (PBSX prophage-mediated lysis); RBL01179 YP_091162.1 putative holin; RBL05420 YP_091163.1 RBL01181 YP_091164.1 RBL05419 YP_091165.1 RBL01182 YP_091166.1 RBL01183 YP_091167.1 putative integrase-phage associated; RBL01184 YP_091168.1 RBL05063 YP_091169.1 putative response regulator aspartate phosphatase H; RBL05062 YP_091170.1 putative response regulator aspartate phosphatase H; RBL05061 YP_091171.1 putative response regulator aspartate phosphatase H; RBL05060 YP_091172.1 RBL01185 YP_091173.1 similar to transcriptional regulator; RBL05059 YP_091174.1 RBL01186 YP_091175.1 RBL05058 YP_091176.1 RBL05057 YP_091177.1 RBL01188 YP_091178.1 RBL05418 YP_091179.1 RBL01189 YP_091180.1 RBL05055 YP_091181.1 RBL05054 YP_091182.1 similar to spore cortex-lytic enzyme; RBL01190 YP_091183.1 similar to spore cortex membrane protein; RBL01191 YP_091184.1 similar to thioredoxin; RBL01192 YP_091185.1 similar to heavy metal-transporting ATPase; RBL01193 YP_091186.1 similar to Xaa-Pro dipeptidase; RBL01194 YP_091187.1 RBL01195 YP_091188.1 similar to transcriptional regulator (LacI family); RBL01196 YP_091189.1 transcriptional antiterminator essential for the expression of the ptsGHI operon; RBL02128 YP_091190.1 PTS glucose-specific enzyme IICBA component; RBL02127 YP_091191.1 histidine-containing phosphocarrier protein of the PTS (HPr protein); RBL05053 YP_091192.1 PTS enzyme I; RBL02125 YP_091193.1 transcriptional negative regulator of the spore photoproduct lyase operon; RBL05976 YP_091194.1 spore photoproduct lyase; RBL02123 YP_091195.1 similar to proteins from B. subtilis; RBL02121 YP_091196.1 methyl-accepting chemotaxis protein; RBL02119 YP_091197.1 putative acyl carrier protein reductase; RBL02117 YP_091198.1 similar to 3-hydroxyisobutyrate dehydrogenase; RBL02115 YP_091199.1 similar to proteins from B. subtilis; RBL02113 YP_091200.1 similar to penicillin-binding protein; RBL02112 YP_091201.1 two-component sensor histidine kinase involved in the initiation of sporulation; RBL02111 YP_091202.1 RBL02109 YP_091203.1 RBL02107 YP_091204.1 RBL02106 YP_091205.1 modulation of CheA activity in response to attractants; RBL02104 YP_091206.1 RBL02103 YP_091207.1 similar to macrolide-efflux protein; RBL05052 YP_091208.1 RBL02269 YP_091209.1 RBL05977 YP_091210.1 RBL02271 YP_091211.1 similar to glucose 1-dehydrogenase; RBL02272 YP_091212.1 RBL02273 YP_091213.1 RBL02274 YP_091214.1 RBL05051 YP_091215.1 RBL02275 YP_091216.1 RBL05050 YP_091217.1 RBL02276 YP_091218.1 transcriptional regulator mediating carbon catabolite repression; RBL02277 YP_091219.1 similar to flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_091220.1 RBL02281 YP_091221.1 similar to flavodoxin; RBL05414 YP_091222.1 similar to tetrahydrodipicolinate succinylase; RBL05413 YP_091223.1 similar to hippurate hydrolase; RBL05978 YP_091224.1 RBL04958 YP_091225.1 similar to 2-cys peroxiredoxin; RBL02148 YP_091226.1 RBL02150 YP_091227.1 repressor of comK; RBL02151 YP_091228.1 similar to sporulation protein sigma-E-controlled; RBL02152 YP_091229.1 molybdopterin-guanine dinucleotide biosynthesis; RBL02153 YP_091230.1 molybdopterin biosynthesis protein; catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways YP_091231.1 molybdopterin biosynthesis protein; RBL02155 YP_091232.1 molybdopterin-guanine dinucleotide biosynthesis; RBL02156 YP_091233.1 molybdopterin converting factor (subunit 2); RBL04957 YP_091234.1 molybdopterin converting factor (subunit 1); RBL04956 YP_091235.1 RBL02158 YP_091236.1 similar to ABC transporter (ATP-binding protein); RBL02159 YP_091237.1 similar to ABC transporter (ATP-binding protein); RBL02160 YP_091238.1 RBL02161 YP_091239.1 similar to proteins from B. subtilis; RBL02162 YP_091240.1 similar to ABC transporter (ATP-binding protein); RBL02163 YP_091241.1 RBL02164 YP_091242.1 transcriptional repressor of the fructose operon; RBL02165 YP_091243.1 fructose 1-phosphate kinase; RBL02166 YP_091244.1 PTS fructose-specific enzyme IIABC component; RBL02167 YP_091245.1 signal peptidase I; RBL04955 YP_091246.1 RBL05412 YP_091247.1 RBL05411 YP_091248.1 similar to ABC transporter (ATP-binding protein); RBL01335 YP_091249.1 RBL01337 YP_091250.1 aminopeptidase; RBL01338 YP_091251.1 similar to proteins from B. subtilis; RBL04954 YP_091252.1 cell-shape determining protein; RBL01339 YP_091253.1 transcriptional regulator of transition state genes (AbrB-like); RBL04953 YP_091254.1 two-component sensor histidine kinase involved in the initiation of sporulation; RBL01341 YP_091255.1 similar to potassium uptake protein; RBL01342 YP_091256.1 adenine deaminase; RBL01343 YP_091257.1 RBL01344 YP_091258.1 RBL04952 YP_091259.1 RBL01345 YP_091260.1 similar to formylmethionine deformylase; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_091261.1 RBL04951 YP_091262.1 RBL01347 YP_091263.1 pyruvate dehydrogenase (E1 alpha subunit); RBL01349 YP_091264.1 pyruvate dehydrogenase (E1 beta subunit); RBL01351 YP_091265.1 pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA YP_091266.1 pyruvate dehydrogenase / 2-oxoglutarate dehydrogenase (dihydrolipoamide dehydrogenase E3 subunit); E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_091267.1 putative transposase; RBL05987 YP_091268.1 putative transposase; RBL06011 YP_091269.1 small peptidoglycan-associated lipoprotein; RBL01357 YP_091270.1 arginine decarboxylase; RBL01359 YP_091271.1 RBL04949 YP_091272.1 RBL01361 YP_091273.1 RBL04948 YP_091274.1 similar to inositol monophosphatase; RBL03870 YP_091275.1 RBL03871 YP_091276.1 RBL03872 YP_091277.1 RBL04947 YP_091278.1 similar to RNA polymerase ECF-type sigma factor; RBL03873 YP_091279.1 RBL04946 YP_091280.1 RBL04945 YP_091281.1 similar to GTP-binding elongation factor; RBL03875 YP_091282.1 RBL03876 YP_091283.1 RBL03877 YP_091284.1 similar to monooxygenase; RBL03878 YP_091285.1 RBL04944 YP_091286.1 similar to proteins from B. subtilis; RBL03880 YP_091287.1 similar to phosphate starvation inducible protein; RBL03882 YP_091288.1 RBL03884 YP_091289.1 similar to glutaminase; catalyzes the formation of glutamate from glutamine YP_091290.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; putative ligand binding protein YP_091291.1 cell-division protein; RBL03886 YP_091292.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_091293.1 cytochrome caa3 oxidase (required for biosynthesis); RBL03890 YP_091294.1 cytochrome caa3 oxidase (assembly factor); converts protoheme IX and farnesyl diphosphate to heme O YP_091295.1 cytochrome caa3 oxidase (subunit II); RBL03892 YP_091296.1 cytochrome caa3 oxidase (subunit I); RBL03893 YP_091297.1 cytochrome caa3 oxidase (subunit III); RBL03894 YP_091298.1 cytochrome caa3 oxidase (subunit IV); RBL03895 YP_091299.1 function; RBL03896 YP_091300.1 RBL05116 YP_091301.1 similar to IMP dehydrogenase; RBL04942 YP_091302.1 similar to proteins from B. subtilis; RBL04018 YP_091303.1 RBL04017 YP_091304.1 RBL04941 YP_091305.1 RBL04016 YP_091306.1 RBL04014 YP_091307.1 RBL04940 YP_091308.1 similar to lipopolysaccharide core biosynthesis; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_091309.1 RBL04938 YP_091310.1 RBL05406 YP_091311.1 RBL05405 YP_091312.1 RBL04789 YP_091313.1 ribosomal protein L32; some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_091314.1 similar to proteins from B. subtilis; RBL04786 YP_091315.1 RBL04785 YP_091316.1 similar to 2-dehydropantoate 2-reductase; ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_091317.1 RBL00249 YP_091318.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_091319.1 RBL00247 YP_091320.1 cell-division protein (septum formation); RBL00245 YP_091321.1 penicillin-binding protein 2B (cell-division septum); RBL00243 YP_091322.1 penicillin-binding protein (spore cortex); RBL00241 YP_091323.1 UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_091324.1 phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_091325.1 UDP-N-acetylmuramoylalanyl-D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_091326.1 required for spore cortex peptidoglycan synthesis; RBL00233 YP_091327.1 UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_091328.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_091329.1 cell-division initiation protein (septum formation); RBL00228 YP_091330.1 RBL00226 YP_091331.1 RBL00225 YP_091332.1 small basic protein; RBL00224 YP_091333.1 cell-division protein (septum formation); RBL00223 YP_091334.1 cell-division initiation protein (septum formation); GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_091335.1 putative bacillopeptidase F; RBL00220 YP_091336.1 bacillopeptidase F; RBL00219 YP_091337.1 protease (processing of pro-sigma-E to active sigma-E); RBL00218 YP_091338.1 RNA polymerase sporulation mother cell-specific (early) sigma factor; sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation YP_091339.1 RNA polymerase sporulation forespore-specific (late) sigma factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin YP_091340.1 similar to ABC transporter (ATP-binding protein); RBL00215 YP_091341.1 putative rRNA (guanine-N1-) methyltransferase; RBL05404 YP_091342.1 RBL00214 YP_091343.1 RBL04783 YP_091344.1 RBL00213 YP_091345.1 RBL00212 YP_091346.1 RBL00211 YP_091347.1 RBL04782 YP_091348.1 RBL00210 YP_091349.1 cell-division initiation protein (septum placement); RBL00209 YP_091350.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_091351.1 similar to proteins from B. subtilis; RBL00205 YP_091352.1 RBL05981 YP_091353.2 signal peptidase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_091354.1 similar to pseudouridylate synthase; RBL05982 YP_091355.1 transcriptional attenuation of the pyrimidine operon / uracil phosphoribosyltransferase activity; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_091356.1 uracil permease; RBL00422 YP_091357.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_091358.1 dihydroorotase; RBL00420 YP_091359.1 carbamoyl-phosphate synthetase (glutaminase subunit); catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_091360.1 carbamoyl-phosphate synthetase (catalytic subunit); four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_091361.1 dihydroorotate dehydrogenase (electron transfer subunit); responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_091362.1 dihydroorotate dehydrogenase (catalytic subunit); catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_091363.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_091364.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_091365.1 RBL04778 YP_091366.1 putative phosphoadenosine phosphosulfate reductase; RBL04074 YP_091367.1 sulfate permease; RBL04073 YP_091368.1 probable sulfate adenylyltransferase; ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_091369.1 probable adenylylsulfate kinase; RBL04070 YP_091370.1 similar to uroporphyrin-III C-methyltransferase; RBL04068 YP_091371.1 RBL04067 YP_091372.1 similar to uroporphyrin-III C-methyltransferase; RBL04066 YP_091373.1 similar to fibronectin-binding protein; RBL04064 YP_091374.1 similar to calcium-transporting ATPase; RBL04063 YP_091375.1 RBL04062 YP_091376.1 RBL04777 YP_091377.1 Essential for recycling GMP and indirectly, cGMP YP_091378.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_091379.1 similar to pantothenate metabolism flavoprotein; RBL04059 YP_091380.1 primosomal replication factor Y; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_091381.1 polypeptide deformylase; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_091382.1 methionyl-tRNA formyltransferase; RBL04056 YP_091383.1 similar to RNA-binding Sun protein; RBL04054 YP_091384.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_091385.1 protein phosphatase; RBL04052 YP_091386.1 probable membrane-linked protein kinase; RBL04051 YP_091387.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_091388.1 probable ribulose-5-phosphate 3-epimerase; catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_091389.1 RBL04047 YP_091390.1 required for normal spore cortex and coat synthesis; involved in the production of the spore cortex and coat YP_091391.1 ribosomal protein L28; required for 70S ribosome assembly YP_091392.1 similar to alkaline-shock protein; RBL04045 YP_091393.1 RBL04044 YP_091394.1 probable L-serine dehydratase (beta chain); RBL04043 YP_091395.1 probable L-serine dehydratase (alpha chain); RBL04042 YP_091396.1 probable ATP-dependent DNA helicase; catalyzes branch migration in Holliday junction intermediates YP_091397.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_091398.1 involved in fatty acid/phospholipid synthesis; involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_091399.1 malonyl CoA-acyl carrier protein transacylase; RBL04038 YP_091400.1 beta-ketoacyl-acyl carrier protein reductase; RBL04037 YP_091401.1 carries the fatty acid chain in fatty acid biosynthesis YP_091402.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_091403.1 chromosome condensation and segregation SMC protein; RBL04035 YP_091404.1 signal recognition particle; RBL04033 YP_091405.1 RBL04032 YP_091406.1 signal recognition particle-like (SRP) component; RBL04772 YP_091407.1 ribosomal protein S16 (BS17); binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_091408.1 RBL04770 YP_091409.1 RBL04769 YP_091410.1 probable 16S rRNA processing protein; Essential for efficient processing of 16S rRNA YP_091411.1 tRNA methyltransferase; methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_091412.1 ribosomal protein L19; this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_091413.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_091414.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_091415.1 RBL01703 YP_091416.1 similar to flagellar biosynthetic protein; RBL04765 YP_091417.1 succinyl-CoA synthetase (beta subunit); catalyzes the interconversion of succinyl-CoA and succinate YP_091418.1 succinyl-CoA synthetase (alpha subunit); Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_091419.1 DNA processing Smf protein homolog; RBL04764 YP_091420.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_091421.1 glucose-inhibited division protein; TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_091422.1 site-specific integrase/recombinase involved in normal chromosome partitioning; site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_091423.1 two-component ATP-dependent protease [ClpY]; heat shock protein involved in degradation of misfolded proteins YP_091424.1 two-component ATP-dependent protease [ClpQ]; heat shock protein involved in degradation of misfolded proteins YP_091425.1 transcriptional pleiotropic repressor; CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_091426.1 flagellar basal-body rod protein; with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_091427.1 flagellar basal-body rod protein; with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_091428.1 flagellar hook-basal body protein; forms a junction between the M-ring and FlgB during flagella biosynthesis YP_091429.1 flagellar basal-body M-ring protein; the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_091430.1 flagellar motor switch protein; One of three proteins involved in switching the direction of the flagellar rotation YP_091431.1 flagellar assembly protein; binds to and inhibits the function of flagella specific ATPase FliI YP_091432.1 flagellar-specific ATP synthase; involved in type III protein export during flagellum assembly YP_091433.1 flagellar protein required for formation of basal body; rod/hook and filament chaperone YP_091434.1 RBL02251 YP_091435.1 flagellar hook-length control; RBL02250 YP_091436.1 similar to flagellar hook assembly protein; acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod YP_091437.1 flagellar hook protein; makes up the distal portion of the flagellar basal body rod YP_091438.1 putative flagellar protein; RBL04762 YP_091439.1 flagellar protein required for flagellar formation; interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_091440.1 flagellar motor switch protein; with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_091441.1 One of three proteins involved in switching the direction of the flagellar rotation YP_091442.1 two-component response regulator involved in modulation of flagellar switch bias; RBL02243 YP_091443.1 flagellar protein required for flagellar formation; possible structural component of the flagellum that anchors the rod to the membrane YP_091444.1 flagellar protein required for flagellar formation; FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_091445.1 flagellar protein required for flagellar formation; with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_091446.1 flagellar protein required for flagellar formation; FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_091447.1 flagella-associated protein; membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_091448.1 flagella-associated protein; membrane protein involved in the flagellar export apparatus YP_091449.1 flagella-associated protein; positive regulator of class III flagellar genes YP_091450.1 similar to flagellar biosynthesis switch protein; RBL02234 YP_091451.1 MCP-glutamate methylesterase / two-component response regulator-like; regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_091452.1 two-component sensor histidine kinase chemotactic signal modulator; RBL02232 YP_091453.1 modulation of CheA activity in response to attractants; RBL02230 YP_091454.1 inhibition of CheR-mediated methylation of MCPs; RBL02229 YP_091455.1 required for methylation of methyl-accepting chemotaxis proteins by CheR; catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_091456.1 RNA polymerase flagella, motility, chemotaxis and autolysis sigma factor; expressed in late exponential phase; controls the expression of genes coding cell surface proteins involved in chemotaxis, flagellar assembly, and autolysis YP_091457.1 RBL02225 YP_091458.1 ribosomal protein S2; one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_091459.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_091460.1 Catalyzes the phosphorylation of UMP to UDP YP_091461.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_091462.1 probable UDP pyrophosphate synthetase; catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate YP_091463.1 phosphatidate cytidylyltransferase; RBL04105 YP_091464.1 probable 1-deoxy-D-xylulose-5-phosphate reductoisomerase; catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_091465.1 RBL04103 YP_091466.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_091467.1 DNA polymerase III (alpha subunit); catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_091468.1 putative endo-1,4-glucanase; RBL04092 YP_091469.1 putative cellulose 1,4-beta-cellobiosidase; RBL04091 YP_091470.1 putative cellulase; RBL04089 YP_091471.1 putative endo-1,4-beta-mannosidase; RBL04088 YP_091472.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_091473.1 transcription termination; modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_091474.1 RBL05983 YP_091475.1 similar to ribosomal protein L7AE family; RBL02512 YP_091476.1 initiation factor IF-2; Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_091477.1 RBL05400 YP_091478.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_091479.1 tRNA pseudouridine 5S synthase; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_091480.1 riboflavin kinase / FAD synthase; catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_091481.1 ribosomal protein S15 (BS18); primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_091482.1 polynucleotide phosphorylase (PNPase); RBL01917 YP_091483.1 similar to deacetylase; RBL01918 YP_091484.1 mitochondrial processing peptidase-like; RBL01919 YP_091485.1 RBL05397 YP_091486.1 catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance YP_091487.1 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme YP_091488.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_091489.1 aspartokinase I (alpha and beta subunits); catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive YP_091490.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_091491.1 RBL01926 YP_091492.1 translocation-enhancing protein required for efficient pre-protein translocation; RBL01927 YP_091493.1 RBL05396 YP_091494.1 DNA translocase required for chromosome partitioning through the septum into the forespore; RBL01671 YP_091495.1 similar to transcriptional regulator (GntR family); RBL01672 YP_091496.1 putative cell wall-binding protein; RBL01674 YP_091497.1 putative zinc protease; RBL01675 YP_091498.1 similar to processing protease; RBL01679 YP_091499.1 similar to 3-oxoacyl- acyl-carrier protein reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_091500.1 similar to proteins from B. subtilis; RBL05690 YP_091501.1 RBL05691 YP_091502.1 RBL05999 YP_091503.1 phosphatidylglycerophosphate synthase; RBL05694 YP_091504.1 competence-damage inducible protein; RBL05695 YP_091505.1 multifunctional protein involved in homologous recombination and DNA repair (LexA-autocleavage); catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_091506.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_091507.1 RBL05698 YP_091508.1 required for dehydratation of the spore core and assembly of the coat; RBL05699 YP_091509.1 putative dipeptidase; RBL02334 YP_091510.1 threonine 3-dehydrogenase; converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_091511.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_091512.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_091513.1 RBL02341 YP_091514.1 spore coat protein (outer); RBL05115 YP_091515.1 DNA mismatch repair (recognition); This protein performs the mismatch recognition step during the DNA repair process YP_091516.1 DNA mismatch repair; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_091517.1 RBL05341 YP_091518.1 RBL05342 YP_091519.1 RBL05343 YP_091520.1 RBL02349 YP_091521.1 NADH dehydrogenase; RBL02350 YP_091522.1 putative phosphinothricin N-acetyltransferase; RBL02351 YP_091523.1 RBL02352 YP_091524.1 putative L-amino acid oxidase precursor; RBL02353 YP_091525.1 similar to L-amino acid oxidase; RBL02354 YP_091526.1 RBL02355 YP_091527.1 putative Na+/H+ antiporter; the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_091528.1 putative tetracycline resistance protein; RBL02357 YP_091529.1 putative tetracycline resistance protein; RBL02358 YP_091530.1 RBL05344 YP_091531.1 putative hydrolase; RBL02359 YP_091532.1 RBL02360 YP_091533.1 RBL02361 YP_091534.1 putative penicillin-binding protein; RBL02362 YP_091535.1 similar to macrolide glycosyltransferase; RBL02364 YP_091536.1 similar to permease; RBL02365 YP_091537.1 similar to spore coat protein; RBL05700 YP_091538.1 putative spore coat protein; RBL05701 YP_091539.1 putative ABC transporter (ATP-binding protein); RBL02368 YP_091540.1 similar to transcriptional regulator (TetR family); RBL02369 YP_091541.1 RBL02370 YP_091542.1 RBL02371 YP_091543.1 RBL05702 YP_091544.1 RBL02372 YP_091545.1 multidrug resistance protein; RBL02373 YP_091546.1 multidrug resistance protein; RBL02374 YP_091547.1 RBL05703 YP_091548.1 tRNA isopentenylpyrophosphate transferase; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_091549.1 similar to host factor-1 protein; Stimulates the elongation of poly(A) tails YP_091550.1 RBL05349 YP_091551.1 similar to NrdI protein; in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_091552.1 ribonucleoside-diphosphate reductase (major subunit); Catalyzes the rate-limiting step in dNTP synthesis YP_091553.1 ribonucleoside-diphosphate reductase (minor subunit); B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_091554.1 RBL04147 YP_091555.1 RBL04149 YP_091556.1 RBL04150 YP_091557.1 putative transcriptional repressor of the peroxide regulon; RBL05350 YP_091558.1 putative transcriptional regulator, GntR family; RBL04152 YP_091559.1 similar to intracellular alkaline protease; RBL04153 YP_091560.1 N-acetylmuramoyl-L-alanine amidase cwlL precursor (Cell wall hydrolase) (Autolysin); RBL04154 YP_091561.1 RBL04157 YP_091562.1 RBL04158 YP_091563.1 RBL05351 YP_091564.1 RBL05352 YP_091565.1 putative transcriptional regulator TetR/AcrR family; RBL01241 YP_091566.1 RBL05353 YP_091567.1 putative cytosine permease; RBL01242 YP_091568.1 putative N-methylhydantoinase (ATP-hydrolyzing); RBL01243 YP_091569.1 putative N-methylhydantoinase B; RBL01245 YP_091570.1 putative N-methylhydantoinase B; RBL01246 YP_091571.1 RBL01248 YP_091572.1 RBL05354 YP_091573.1 RBL01249 YP_091574.1 disruption leads to the production of immature spores; RBL01250 YP_091575.1 similar to GTP-binding protein protease modulator; RBL01252 YP_091576.1 similar to aluminum resistance protein; RBL01254 YP_091577.1 transcriptional repressor of the glutamine synthetase gene; RBL01255 YP_091578.1 glutamine synthetase; RBL01256 YP_091579.1 RBL05357 YP_091580.1 RBL05705 YP_091581.1 RBL01257 YP_091582.1 RBL05706 YP_091583.1 RBL05707 YP_091584.1 RBL05359 YP_091585.1 RBL01258 YP_091586.1 RBL05360 YP_091587.1 RBL05361 YP_091588.1 putative short chain dehydrogenase; RBL01259 YP_091589.1 similar to proteins from B. subtilis; RBL01260 YP_091590.1 RBL01261 YP_091591.1 RBL01262 YP_091592.1 RBL05362 YP_091593.1 RBL01263 YP_091594.1 similar to transcriptional regulator (TetR/AcrR family); RBL01264 YP_091595.1 similar to molecular chaperone; RBL05363 YP_091596.1 similar to molecular chaperone; RBL05364 YP_091597.1 putative acetyltransferase; RBL01268 YP_091598.1 RBL01269 YP_091599.1 RBL01270 YP_091600.1 putative cytochrome c biogenesis (thioredoxin); RBL05708 YP_091601.1 putative manganese-containing catalase; RBL01271 YP_091602.1 RBL01272 YP_091603.1 putative acetyl transferase; RBL01273 YP_091604.1 RBL01274 YP_091605.1 RBL01275 YP_091606.1 putative transcriptional regulator MarR family; RBL05366 YP_091607.1 similar to NAD(P)H nitroreductase; RBL01276 YP_091608.1 RBL01277 YP_091609.1 RBL01278 YP_091610.1 RBL01279 YP_091611.1 RBL01280 YP_091612.1 RBL01281 YP_091613.1 thymidylate synthase A; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_091614.1 sporulation-specific extracellular nuclease; RBL05625 YP_091615.1 transcriptional repressor of the SOS regulon; Represses a number of genes involved in the response to DNA damage YP_091616.1 RBL05626 YP_091617.1 similar to resolvase; RBL05627 YP_091618.1 RBL05711 YP_091619.1 transketolase; RBL03108 YP_091620.1 RBL03107 YP_091621.1 RBL05296 YP_091622.1 RBL05297 YP_091623.1 required for a late step of cytochrome c synthesis; RBL03106 YP_091624.1 similar to two-component response regulator (CheY homolog); RBL05298 YP_091625.1 RBL03104 YP_091626.1 RBL03103 YP_091627.1 spore coat protein (outer); RBL03101 YP_091628.1 probable small acid-soluble spore protein (minor); SASP P; found in forespore compartment YP_091629.1 small acid-soluble spore protein (minor); SASP O; found in forespore compartment YP_091630.1 Catalyzes the conversion of citrate to isocitrate YP_091631.1 similar to thioldisulfide interchange protein; RBL03098 YP_091632.1 RBL05713 YP_091633.1 small acid-soluble spore protein, minor; SASP N; found in forespore compartment YP_091634.1 small acid-soluble spore protein (thioredoxin-like protein); RBL05715 YP_091635.1 RBL03096 YP_091636.1 RBL03095 YP_091637.1 RBL05301 YP_091638.1 RBL03094 YP_091639.1 RBL03093 YP_091640.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_091641.1 RBL04431 YP_091642.1 subunit of DNA topoisomerase IV; decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_091643.1 subunit of DNA topoisomerase IV; decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_091644.1 transcriptional repressor of the arabinose operons; RBL01000 YP_091645.1 putative sugar kinase, possible xylulose kinase; RBL00999 YP_091646.1 putative L-ribulose-5-phosphate 4-epimerase; catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_091647.1 close homolog to AraA L-arabinose isomerase; catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_091648.1 putative sugar transporter; RBL00996 YP_091649.1 putative acetoin reductase; RBL00995 YP_091650.1 RBL05302 YP_091651.1 RBL00994 YP_091652.1 amino acid carrier protein; RBL01838 YP_091653.1 RBL04705 YP_091654.1 nitrate reductase (gamma subunit); RBL01836 YP_091655.1 nitrate reductase (protein J); RBL01835 YP_091656.1 nitrate reductase (beta subunit); RBL01833 YP_091657.1 nitrate reductase (alpha subunit); RBL01829 YP_091658.1 RBL01826 YP_091659.1 RBL05716 YP_091660.1 RBL01825 YP_091661.1 regulation of anaerobic genes; RBL05303 YP_091662.1 RBL03981 YP_091663.1 transcriptional regulator of anaerobic genes; RBL03980 YP_091664.1 nitrite extrusion protein; RBL03979 YP_091665.1 RBL05717 YP_091666.1 putative transcriptional regulator (Fnr/Crp family); RBL03977 YP_091667.1 putative nitric-oxide reductase subunit B; RBL03976 YP_091668.1 RBL03975 YP_091669.1 RBL03974 YP_091670.1 endo-1,4-beta-glucanase; RBL03973 YP_091671.1 RBL03972 YP_091672.1 similar to N-acetyltransferase; RBL03971 YP_091673.1 RBL03970 YP_091674.1 putative pyridine nucleotide-disulphide oxidoreductase; RBL03969 YP_091675.1 putative methyltransferase; RBL03968 YP_091676.1 RBL05306 YP_091677.1 RBL03966 YP_091678.1 branched-chain amino acid transporter; RBL03965 YP_091679.1 NADP-dependent alcohol dehydrogenase; RBL01928 YP_091680.1 putative transcriptional regulator; RBL01929 YP_091681.1 putative catabolite repression HPr-like protein; RBL04894 YP_091682.1 RBL01930 YP_091683.1 RBL04895 YP_091684.1 putative enoyl(3-hydroxyisobutyryl)-coenzyme A hydratase protein; catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_091685.1 putative enoyl-CoA hydratase; RBL01933 YP_091686.1 methylmalonate-semialdehyde dehydrogenase; RBL01934 YP_091687.1 putative 2-hydroxy-3-oxopropionate reductase; RBL01935 YP_091688.1 putative butyryl-CoA dehydrogenase; RBL01937 YP_091689.1 putative mannose-6-phosphate isomerase; RBL01939 YP_091690.1 RBL01940 YP_091691.1 RBL05718 YP_091692.1 putative transcriptional activator of the mannose operon; RBL01941 YP_091693.1 RBL01942 YP_091694.1 putative ABC transporter ATP-binding protein; RBL01943 YP_091695.1 putative transcriptional regulator; RBL01944 YP_091696.1 putative glycerophosphodiester phosphodiesterase; Converts D-mannonate to D-mannuronate YP_091697.1 putative D-mannonate dehydratase; catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_091698.1 putative alpha-glucosidase; RBL01947 YP_091699.1 putative C4-dicarboxylate transporter, large subunit; RBL01948 YP_091700.1 putative dicarboxylate transporter small subunit; RBL01949 YP_091701.1 possible C4-dicarboxylate binding protein; RBL01950 YP_091702.1 close homolog to CcpA transcriptional regulator mediating carbon catabolite repression; RBL01951 YP_091703.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_091704.1 similar to arsenical pump membrane protein; RBL01953 YP_091705.1 similar to transcriptional regulator (ArsR family); RBL01954 YP_091706.1 RBL01955 YP_091707.1 RBL01956 YP_091708.1 probable glucose uptake protein; RBL01957 YP_091709.1 RBL01958 YP_091710.1 RBL01959 YP_091711.1 putative pyruvate formate-lyase activating enzyme; RBL01960 YP_091712.1 putative formate acetyltransferase; RBL01961 YP_091713.1 penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase); RBL01962 YP_091714.1 similar to NADH dehydrogenase; RBL01963 YP_091715.1 RBL01964 YP_091716.1 RBL05309 YP_091717.1 RBL04896 YP_091718.1 putative acetyl-coenzyme A synthetase; RBL01966 YP_091719.1 similar to propionyl-CoA carboxylase; RBL01968 YP_091720.1 similar to 3-hydroxbutyryl-CoA dehydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_091721.1 similar to hydroxymethylglutaryl-CoA lyase; catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_091722.1 putative biotin carboxyl carrier protein; composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_091723.1 similar to biotin carboxylase; an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_091724.1 similar to long-chain acyl-CoA synthetase; activates fatty acids by binding to coenzyme A YP_091725.1 similar to butyryl-CoA dehydrogenase; RBL01976 YP_091726.1 similar to NAD(P)H oxidoreductase; RBL01977 YP_091727.1 similar to cinnamoyl ester hydrolase; RBL01978 YP_091728.1 putative gamma-glutamyl phosphate reductase; RBL01980 YP_091729.1 glutamate 5-kinase; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_091730.1 pyrroline-5-carboxylate reductase; RBL01982 YP_091731.1 similar to proteins from B. subtilis; RBL01983 YP_091732.1 putative sulfate permease; RBL01985 YP_091733.1 similar to phospho-adenylylsulfate sulfotransferase; RBL01986 YP_091734.1 RBL01987 YP_091735.1 similar to proteins from B. subtilis; RBL01988 YP_091736.1 similar to mandelate racemase; RBL01989 YP_091737.1 similar to multidrug resistance protein; RBL01990 YP_091738.1 similar to dolichol phosphate mannose synthase; RBL01991 YP_091739.1 RBL01992 YP_091740.1 glutamate synthase (small subunit); glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_091741.1 glutamate synthase (large subunit); RBL01996 YP_091742.1 transcriptional activator of the glutamate synthase operon; RBL04075 YP_091743.1 RBL04078 YP_091744.1 RBL04080 YP_091745.1 putative transcriptional regulator, MarR/EmrR family; RBL04081 YP_091746.1 similar to ABC transporter (ATP-binding protein); RBL04082 YP_091747.1 similar to ABC transporter (ATP-binding protein); RBL04083 YP_091748.1 putative cinnamoyl ester hydrolase; RBL04084 YP_091749.1 similar to 3-oxoacyl- acyl-carrier protein reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_091750.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_091751.1 lincomycin-resistance protein; RBL03537 YP_091752.1 similar to formate dehydrogenase; RBL03538 YP_091753.1 similar to transcriptional regulator; RBL03539 YP_091754.1 multidrug-efflux transporter (puromycin, nerfloxacin, tosufloxacin); RBL03541 YP_091755.1 similar to spore germination protein; RBL03542 YP_091756.1 similar to spore germination protein; RBL03543 YP_091757.1 putative lipoprotein; RBL03544 YP_091758.1 putative long-chain acyl-CoA synthetase; RBL03545 YP_091759.1 similar to spore germination protein; RBL03546 YP_091760.1 ATP-binding transport protein; RBL03547 YP_091761.1 methyl-accepting chemotaxis protein; RBL03548 YP_091762.1 molecular chaperone involved in protein secretion; RBL03549 YP_091763.1 intracellular alkaline serine protease; RBL03551 YP_091764.1 RBL03552 YP_091765.1 putative transcriptional regulator, TetR family; RBL03553 YP_091766.1 RBL05312 YP_091767.1 RBL01236 YP_091768.1 RBL01237 YP_091769.1 RBL01238 YP_091770.1 RBL01239 YP_091771.1 RBL01240 YP_091772.1 RBL05313 YP_091773.1 RBL01631 YP_091774.1 RBL01632 YP_091775.1 RBL05719 YP_091776.1 RBL05720 YP_091777.1 sporulation membrane protein sigma-K-controlled; RBL01634 YP_091778.1 similar to transcriptional regulator (ArsR family); RBL04619 YP_091779.1 RBL04620 YP_091780.1 similar to metabolite transporter; RBL05314 YP_091781.1 similar to transposon-related protein; RBL05315 YP_091782.1 putative UDP-N-acetylglucosamine 4,6-dehydratase; RBL05316 YP_091783.1 RBL03533 YP_091784.1 RBL03534 YP_091785.1 putative glycosyl transferase; RBL03535 YP_091786.1 RBL03536 YP_091787.1 RBL04581 YP_091788.1 RBL02147 YP_091789.1 putative symporter; uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function YP_091790.1 similar to cell wall-binding protein; RBL02145 YP_091791.1 similar to ATP-dependent DNA helicase; RBL02144 YP_091792.1 RBL02143 YP_091793.1 RBL05317 YP_091794.1 RBL05318 YP_091795.1 RBL04584 YP_091796.1 similar to proteins from B. subtilis; RBL05721 YP_091797.1 similar to formate dehydrogenase; RBL02191 YP_091798.1 RBL05722 YP_091799.1 RBL04234 YP_091800.1 RBL02192 YP_091801.1 RBL05321 YP_091802.1 RBL02193 YP_091803.1 RBL05322 YP_091804.1 RBL05323 YP_091805.1 putative spore germination protein; RBL02194 YP_091806.1 RBL02195 YP_091807.1 putative hydrolase; RBL02196 YP_091808.1 spore coat protein (inner); RBL05723 YP_091809.1 RBL05326 YP_091810.1 similar to chloride peroxidase; RBL02197 YP_091811.1 RBL02198 YP_091812.1 putative transporter; RBL02199 YP_091813.1 putative ribosomal protein S14; located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_091814.1 mutator protein; RBL05328 YP_091815.1 close homolog to Pps phosphoenolpyruvate synthase; catalyzes the formation of phosphoenolpyruvate from pyruvate YP_091816.1 family transcriptional regulator; RBL01873 YP_091817.1 similar to proteins from B. subtilis; RBL01872 YP_091818.1 nuclease inhibitor; RBL01871 YP_091819.1 similar to acyl-carrier protein phosphodiesterase; FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_091820.1 similar to general stress protein; RBL05329 YP_091821.1 RBL00191 YP_091822.1 RBL00192 YP_091823.1 aldehyde dehydrogenase; RBL00195 YP_091824.1 similar to macrolide-efflux transporter; RBL04922 YP_091825.1 RBL00908 YP_091826.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_091827.1 squalene-hopene cyclase; RBL00911 YP_091828.1 superoxide dismutase; RBL00912 YP_091829.1 RBL00913 YP_091830.1 similar to sodium-dependent transporter; RBL00914 YP_091831.1 similar to sodium-dependent transporter; RBL04921 YP_091832.1 2-oxoglutarate dehydrogenase (dihydrolipoamide transsuccinylase, E2 subunit); component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_091833.1 2-oxoglutarate dehydrogenase (E1 subunit); SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_091834.1 RBL00724 YP_091835.1 similar to nitric-oxide reductase; RBL00723 YP_091836.1 similar to superoxide dismutase; RBL00722 YP_091837.1 similar to cell wall-binding protein; RBL00721 YP_091838.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_091839.1 RBL01071 YP_091840.1 RBL01069 YP_091841.1 RBL01068 YP_091842.1 RBL01067 YP_091843.1 RBL01066 YP_091844.1 similar to extracellular endoglucanase precursor; RBL01065 YP_091845.1 RBL04917 YP_091846.1 putative oxidoreductase; RBL01064 YP_091847.1 RBL01063 YP_091848.1 similar to nitroreductase; RBL01062 YP_091849.1 RBL01061 YP_091850.1 RBL04916 YP_091851.1 similar to proline permease; RBL02712 YP_091852.1 putative transposase; RBL06000 YP_091853.1 putative transposase; RBL05990 YP_091854.1 carboxy-terminal processing protease; RBL02710 YP_091855.1 RBL02708 YP_091856.1 RBL04915 YP_091857.1 similar to D-alanyl-D-alanine carboxypeptidase; RBL02707 YP_091858.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_091859.1 putative permease; RBL02704 YP_091860.1 RBL02702 YP_091861.1 RBL02701 YP_091862.1 RBL02700 YP_091863.1 RBL05332 YP_091864.1 RBL02699 YP_091865.1 RBL02698 YP_091866.1 RBL04914 YP_091867.1 lysine 2,3-aminomutase; RBL02697 YP_091868.1 RBL02696 YP_091869.1 similar to succinyl-diaminopimelate desuccinylase; catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_091870.1 similar to butyrate-acetoacetate CoA-transferase; RBL02693 YP_091871.1 similar to 3-oxoadipate CoA-transferase; RBL02692 YP_091872.1 similar to adenosylmethionine-8-amino-7-oxononanoate aminotransferase; RBL02691 YP_091873.1 putative permease; RBL02690 YP_091874.1 maturation of the outermost layer of the spore; RBL00665 YP_091875.1 similar to peptide methionine sulfoxide reductase; this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_091876.1 peptidyl methionine sulfoxide reductase; this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_091877.1 similar to transcriptional regulator (MarR family); RBL00663 YP_091878.1 RBL05333 YP_091879.1 RBL00662 YP_091880.1 RBL00661 YP_091881.1 RBL00660 YP_091882.1 RBL05727 YP_091883.1 RBL00659 YP_091884.1 RBL00658 YP_091885.1 RBL00657 YP_091886.1 RBL00656 YP_091887.1 RBL05334 YP_091888.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_091889.1 similar to transcriptional regulator (sigma-L-dependent); RBL05985 YP_091890.1 similar to hemolysin III homolog; RBL00653 YP_091891.1 RBL00652 YP_091892.1 dihydrofolate reductase; RBL00651 YP_091893.1 similar to low temperature requirement C protein; RBL00650 YP_091894.1 RBL00649 YP_091895.1 RBL00648 YP_091896.1 similar to proteins from B. subtilis; RBL00647 YP_091897.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_091898.1 RBL04477 YP_091899.1 RBL01139 YP_091900.1 putative glutathione peroxidase; RBL01140 YP_091901.1 putative formate-tetrahydrofolate ligase; catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_091902.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_091903.1 UDP-glucose diacylglycerol glucosyltransferase; processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids YP_091904.1 RBL01146 YP_091905.1 cold-shock protein; RBL05335 YP_091906.1 degradative enzyme production; RBL05336 YP_091907.1 RBL05337 YP_091908.1 RBL05338 YP_091909.1 RBL01205 YP_091910.1 RBL01204 YP_091911.1 similar to RNase HI; RBL01203 YP_091912.1 small acid-soluble spore protein (minor); RBL05728 YP_091913.1 similar to DNA polymerase I; RBL01202 YP_091914.1 RBL05729 YP_091915.1 RBL05339 YP_091916.1 RBL01201 YP_091917.1 RBL01138 YP_091918.1 naringenin-chalcone synthase; RBL01136 YP_091919.1 putative acetyltransferase; RBL05340 YP_091920.1 xanthine permease; RBL01134 YP_091921.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_091922.1 similar to carboxypeptidase; RBL01132 YP_091923.1 similar to ATP-dependent helicase; RBL05633 YP_091924.1 RBL05730 YP_091925.1 RBL03594 YP_091926.1 RBL03593 YP_091927.1 GpsB; guiding PBP1 shuttling; similar to DivIVA YP_091928.1 similar to proteins from B. subtilis; RBL03591 YP_091929.1 spore coat protein (inner); RBL05095 YP_091930.1 RBL03590 YP_091931.1 similar to ATP-dependent helicase; RBL03589 YP_091932.1 similar to phosphotransferase system enzyme II; RBL03588 YP_091933.1 RBL03586 YP_091934.1 RBL03585 YP_091935.1 RBL03583 YP_091936.1 RBL03582 YP_091937.1 RBL03581 YP_091938.1 RBL03580 YP_091939.1 DNA repair, homologous recombination and chromosome segregation; functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_091940.1 penicillin-binding proteins 1A/1B; RBL03578 YP_091941.1 RBL03575 YP_091942.1 endonuclease III (DNA repair); RBL03574 YP_091943.1 initiation of chromosome replication; RBL03573 YP_091944.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_091945.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_091946.1 RBL03569 YP_091947.1 RBL05094 YP_091948.1 ATP-dependent DNA helicase; unwinds DNA YP_091949.1 aspartate 1-decarboxylase; Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_091950.1 pantothenate synthetase; catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_091951.1 ketopantoate hydroxymethyltransferase; catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_091952.1 transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; RBL03563 YP_091953.1 tRNA nucleotidyltransferase; catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_091954.1 similar to lipopolysaccharide biosynthesis-related protein; RBL03560 YP_091955.1 RBL03559 YP_091956.1 probable methylglyoxal synthase; catalyzes the formation of methylglyoxal from glycerone phosphate YP_091957.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_091958.1 RBL03555 YP_091959.1 RBL03554 YP_091960.1 RBL05093 YP_091961.1 RBL05092 YP_091962.1 menaquinolcytochrome c oxidoreductase (cytochrome b/c subunit); RBL03466 YP_091963.1 menaquinolcytochrome c oxidoreductase (cytochrome b subunit); electron transport protein YP_091964.1 menaquinolcytochrome c oxidoreductase (iron-sulfur subunit); RBL03464 YP_091965.1 RBL03463 YP_091966.1 RBL03462 YP_091967.1 RBL03461 YP_091968.1 5-enolpyruvoylshikimate-3-phosphate synthase; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_091969.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_091970.1 histidinol-phosphate aminotransferase / tyrosine and phenylalanine aminotransferase; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_091971.1 tryptophan synthase (alpha subunit); catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_091972.1 tryptophan synthase (beta subunit); catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_091973.1 phosphoribosyl anthranilate isomerase; catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_091974.1 indol-3-glycerol phosphate synthase; involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_091975.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_091976.1 anthranilate synthase; with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_091977.1 chorismate mutase (isozymes 1 and 2); RBL03446 YP_091978.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_091979.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_091980.1 MCPs methyltransferase; RBL03443 YP_091981.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_091982.1 heptaprenyl diphosphate synthase component II; RBL03441 YP_091983.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_091984.1 heptaprenyl diphosphate synthase component I; RBL03439 YP_091985.1 tryptophan operon RNA-binding attenuation protein (TRAP); tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination YP_091986.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_091987.1 non-specific DNA-binding protein HBsu; RBL05090 YP_091988.1 required for proper spore cortex formation and coat assembly; RBL05089 YP_091989.1 RBL05088 YP_091990.1 RBL05087 YP_091991.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_091992.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_091993.1 RBL05274 YP_091994.1 involved in spore envelope assembly; RBL03752 YP_091995.1 RBL03753 YP_091996.1 RBL05085 YP_091997.1 putative isopentenyl-diphosphate delta-isomerase; catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_091998.1 similar to ribosomal protein S1 homolog; in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_091999.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_092000.1 RBL05273 YP_092001.1 RBL01525 YP_092002.1 spore cortex-lytic enzyme; RBL01526 YP_092003.1 RBL01527 YP_092004.1 putative L-asparaginase; RBL01528 YP_092005.1 similar to thioredoxin reductase; RBL01530 YP_092006.1 glutamate dehydrogenase (inactive); RBL01533 YP_092007.1 similar to negative regulation of competence MecA homolog; enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_092008.1 RBL01818 YP_092009.1 RBL01819 YP_092010.1 RBL01820 YP_092011.1 RBL01821 YP_092012.1 putative ATP-dependent DNA helicase; RBL01822 YP_092013.1 RBL01824 YP_092014.1 ferredoxin; RBL05272 YP_092015.1 RBL05271 YP_092016.1 phosphoglycerate dehydrogenase; catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_092017.1 RBL04652 YP_092018.1 negative regulator of sigma-X activity; RBL00831 YP_092019.1 RNA polymerase ECF-type sigma factor; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance YP_092020.1 close homolog to LytR attenuator role for lytABC and lytR expression; RBL00833 YP_092021.1 putative peptidoglycan GlcNAc deacetylase; RBL00834 YP_092022.1 RBL00835 YP_092023.1 putative two-component sensor histidine kinase; RBL00836 YP_092024.1 putative two-component response phosphate regulator; RBL00837 YP_092025.1 two-component sensor histidine kinase involved in aerobic and anaerobic respiration; RBL00840 YP_092026.1 two-component response regulator involved in aerobic and anaerobic respiration; RBL00841 YP_092027.1 essential protein required for cytochrome c synthesis; RBL00843 YP_092028.1 essential protein required for cytochrome c synthesis; RBL00845 YP_092029.1 essential protein similar to cytochrome c biogenesis protein; catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c YP_092030.1 pseudouridine synthase; RBL00848 YP_092031.1 spore maturation protein (spore core dehydratation); RBL00849 YP_092032.1 spore maturation protein (spore core dehydratation); RBL00850 YP_092033.1 penicillin-binding protein 5* (D-alanyl-D-alanine carboxypeptidase); RBL00851 YP_092034.1 similar to proteins from B. subtilis; RBL00852 YP_092035.1 RBL00853 YP_092036.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_092037.1 RBL05732 YP_092038.1 RBL00855 YP_092039.1 reductase; RBL00856 YP_092040.1 riboflavin synthase (beta subunit); RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_092041.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_092042.1 riboflavin synthase (alpha subunit); catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_092043.1 riboflavin-specific deaminase; RBL00860 YP_092044.1 RBL00861 YP_092045.1 putative phosphatase; RBL00862 YP_092046.1 putative stress response homolog Hsp; RBL00863 YP_092047.1 RBL05733 YP_092048.1 response regulator aspartate phosphatase; RBL00865 YP_092049.1 peptidyl-prolyl isomerase; RBL00866 YP_092050.1 RBL00867 YP_092051.1 putative transposase; RBL06001 YP_092052.1 putative transposase; RBL05986 YP_092053.1 similar to phage-related replication protein; RBL00869 YP_092054.1 diaminopimelate decarboxylase; RBL05735 YP_092055.1 RBL05736 YP_092056.1 mutants lead to the production of immature spores; RBL00873 YP_092057.1 mutants lead to the production of immature spores; RBL00874 YP_092058.1 mutants lead to the production of immature spores; RBL05268 YP_092059.1 mutants lead to the production of immature spores; RBL00877 YP_092060.1 mutants lead to the production of immature spores; RBL00878 YP_092061.1 mutants lead to the production of immature spores; RBL00879 YP_092062.1 mutants lead to the production of immature spores; RBL05737 YP_092063.1 RNA polymerase sigma-F factor (stage II sporulation protein AC) (sporulation sigma factor); sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore YP_092064.1 anti-sigma F factor (stage II sporulation protein AB); binds to sigma F preventing its association with RNA polymerase during sporulation YP_092065.1 anti-sigma F factor antagonist (stage II sporulation protein AA); RBL00884 YP_092066.1 penicillin-binding protein (putative D-alanyl-D-alanine carboxypeptidase); RBL00885 YP_092067.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_092068.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_092069.1 site-specific integrase/recombinase involved in proper chromosome partitioning; site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_092070.1 RBL05738 YP_092071.1 transcriptional repressor of iron uptake; RBL05739 YP_092072.1 required for dissolution of the septal cell wall; RBL05740 YP_092073.1 similar to cellobiose phosphotransferase system enzyme II; RBL05741 YP_092074.1 putative PTS cellobiose-specific enzyme IIB; RBL05742 YP_092075.1 similar to permease; RBL05743 YP_092076.1 putative transcriptional regulator (LysR family); RBL05744 YP_092077.1 putative ribosomal protein N-acetyltransferase; RBL05745 YP_092078.1 RBL02130 YP_092079.1 RBL02131 YP_092080.1 ADP-ribose pyrophosphatase; RBL02132 YP_092081.1 RBL05746 YP_092082.1 RBL02133 YP_092083.1 RBL02134 YP_092084.1 similar to oxidoreductase; RBL02135 YP_092085.1 RBL02136 YP_092086.1 RBL05747 YP_092087.1 RBL02137 YP_092088.1 RBL05748 YP_092089.1 RBL02138 YP_092090.1 RBL05749 YP_092091.1 RBL02140 YP_092092.1 RBL02141 YP_092093.1 extracellular lipase; RBL02142 YP_092094.1 putative ABC transporter; RBL00342 YP_092095.1 putative oligopeptide ABC transporter (permease); RBL00341 YP_092096.1 putative oligopeptide ABC transporter (permease); RBL00340 YP_092097.1 putative dipeptide ABC transporter; RBL00339 YP_092098.1 putative oligopeptide ABC transporter, ATP-binding protein; RBL00338 YP_092099.1 putative DNA-damage-inducible protein; RBL00337 YP_092100.1 putative fibronectin-binding protein; RBL00335 YP_092101.1 RBL05750 YP_092102.1 similar to proteins from B. subtilis; RBL00334 YP_092103.1 UV-damage repair protein; RBL00333 YP_092104.1 RBL05536 YP_092105.1 similar to multidrug resistance protein; RBL00088 YP_092106.1 RBL00087 YP_092107.1 probable pantothenate kinase; catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_092108.1 putative ABC transporter permease protein; RBL00085 YP_092109.1 putative ABC transporter ATP-binding protein; RBL00083 YP_092110.1 RBL00082 YP_092111.1 RBL05537 YP_092112.1 RBL00081 YP_092113.1 similar to phage-related protein; RBL00080 YP_092114.1 similar to ketoacyl reductase; RBL00079 YP_092115.1 RBL00078 YP_092116.1 pyrroline-5-carboxylate reductase; RBL00077 YP_092117.1 similar to amino acid degradation; RBL00075 YP_092118.1 similar to NADH-dependent flavin oxidoreductase; catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds YP_092119.1 similar to proteins from B. subtilis; RBL00073 YP_092120.1 putative ribosomal protein L33; in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_092121.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_092122.1 probable glucose-6-phosphate 1-dehydrogenase; catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_092123.1 RBL00070 YP_092124.1 amino acid permease; RBL00069 YP_092125.1 RBL00067 YP_092126.1 similar to transcriptional regulator (GntR family); RBL01669 YP_092127.1 similar to beta-glucosidase; RBL01668 YP_092128.1 putative PTS system, cellobiose-specific enzyme II, C component; RBL01666 YP_092129.1 putative ABC transporter (ATP-binding protein); RBL01665 YP_092130.1 similar to cellobiose phosphotransferase system enzyme II; RBL01663 YP_092131.1 similar to cellobiose phosphotransferase system enzyme II; RBL01662 YP_092132.1 alkaline phosphatase III; RBL01661 YP_092133.1 glucose 1-dehydrogenase; Converts glucose to D-glucono-1,5 lactone YP_092134.1 similar to 6-phosphogluconate dehydrogenase (pentose phosphate); catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_092135.1 similar to DNA-damage repair protein; involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_092136.1 RBL05540 YP_092137.1 similar to lipoprotein SpoIIIJ-like; involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_092138.1 similar to tripeptidase; RBL01653 YP_092139.1 similar to propionyl-CoA carboxylase; RBL01651 YP_092140.1 RBL04299 YP_092141.1 similar to amino acid ABC transporter (ATP-binding protein); RBL04297 YP_092142.1 similar to amino acid ABC transporter (permease); RBL04295 YP_092143.1 putative amino acid ABC transporter (binding protein); RBL05541 YP_092144.1 similar to amino acid ABC transporter (binding protein); RBL02484 YP_092145.1 similar to proteins from B. subtilis; RBL02483 YP_092146.1 multidrug resistance protein cotranscribed with bmr; RBL02482 YP_092147.1 branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase); Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA YP_092148.1 branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase beta subunit); RBL02480 YP_092149.1 branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase alpha subunit); RBL02479 YP_092150.1 probable branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase); E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_092151.1 probable branched-chain fatty-acid kinase (butyrate kinase); catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate YP_092152.1 RBL02473 YP_092153.1 probable phosphate butyryltransferase; catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate YP_092154.1 transcriptional activator involved in the control of isoleucine and valine utilization as sole nitrogen sources; RBL02469 YP_092155.1 RBL05544 YP_092156.1 similar to glycerophosphodiester phosphodiesterase; RBL05545 YP_092157.1 similar to N-acetylmuramoyl-L-alanine amidase; RBL02800 YP_092158.1 similar to lipoprotein; RBL02801 YP_092159.1 RBL05546 YP_092160.1 two-component response regulator central for the initiation of sporulation; RBL02805 YP_092161.1 intercompartmental signalling of pro-sigma-K processing/activation in the mother-cell; RBL02808 YP_092162.1 DNA repair and genetic recombination; RBL02810 YP_092163.1 transcriptional regulator of arginine metabolism expression; regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_092164.1 similar to hemolysin-like; RBL02813 YP_092165.1 probable 1-deoxyxylulose-5-phosphate synthase; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_092166.1 similar to geranyltranstransferase; RBL02816 YP_092167.1 similar to exodeoxyribonuclease VII (small subunit); catalyzes the bidirectional exonucleolytic cleavage of DNA YP_092168.1 similar to exodeoxyribonuclease VII (large subunit); bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_092169.1 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_092170.1 probable transcription termination; Regulates rRNA biosynthesis by transcriptional antitermination YP_092171.1 similar to proteins from B. subtilis; RBL02821 YP_092172.1 acetyl-CoA carboxylase (biotin carboxylase subunit); an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_092173.1 acetyl-CoA carboxylase (biotin carboxyl carrier subunit); composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_092174.1 mutants block sporulation after engulfment; RBL02824 YP_092175.1 mutants block sporulation after engulfment; RBL02825 YP_092176.1 mutants block sporulation after engulfment; RBL02827 YP_092177.1 mutants block sporulation after engulfment; RBL02828 YP_092178.1 mutants block sporulation after engulfment; RBL02829 YP_092179.1 mutants block sporulation after engulfment; RBL04841 YP_092180.1 mutants block sporulation after engulfment; necessary for complete engulfment of forespore YP_092181.1 mutants block sporulation after engulfment; RBL02831 YP_092182.1 RBL04842 YP_092183.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_092184.1 similar to Xaa-Pro dipeptidase; RBL04843 YP_092185.1 similar to 3-dehydroquinate dehydratase; catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_092186.1 RBL04111 YP_092187.1 RBL04112 YP_092188.1 RBL04113 YP_092189.1 RBL04115 YP_092190.1 transcriptional regulator of manganese uptake; involved in manganese homeostasis; activates the transcription of the mntABCD operon YP_092191.1 similar to lipoate protein ligase; RBL04844 YP_092192.1 RBL01839 YP_092193.1 glycine betaine ABC transporter (glycine betaine-binding protein); RBL01841 YP_092194.1 glycine betaine ABC transporter (permease); RBL01842 YP_092195.1 glycine betaine ABC transporter (ATP-binding protein); RBL01843 YP_092196.1 probable glycine decarboxylase (subunit 2); acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_092197.1 probable glycine decarboxylase (subunit 1); acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_092198.1 probable aminomethyltransferase; catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_092199.1 RBL05547 YP_092200.1 similar to SNF2 helicase; RBL01850 YP_092201.1 RBL01851 YP_092202.1 antagonist of SinR; RBL05548 YP_092203.1 transcriptional regulator of post-exponential-phase responses genes; RBL04845 YP_092204.1 translocation-dependent antimicrobial spore component; RBL01852 YP_092205.1 signal peptidase I; RBL01853 YP_092206.1 RBL01854 YP_092207.1 RBL01855 YP_092208.1 RBL05549 YP_092209.1 DNA transport machinery; RBL01856 YP_092210.1 DNA transport machinery; RBL01857 YP_092211.1 DNA transport machinery; RBL05751 YP_092212.1 DNA transport machinery; RBL01859 YP_092213.1 exogenous DNA-binding; RBL04846 YP_092214.1 DNA transport machinery; RBL01860 YP_092215.1 late competence gene; RBL01861 YP_092216.1 similar to positive regulator of sigma-B activity; RBL01862 YP_092217.1 RBL01863 YP_092218.1 RBL04847 YP_092219.1 RBL01864 YP_092220.1 RBL04848 YP_092221.1 RBL01865 YP_092222.1 RBL01866 YP_092223.1 similar to gamma-D-glutamyl-L-diamino acid endopeptidase I; RBL01867 YP_092224.1 ferrichrome ABC transporter (ferrichrome-binding protein); RBL01868 YP_092225.1 similar to putative molybdate binding protein; RBL01869 YP_092226.1 glucose kinase; RBL04850 YP_092227.1 RBL05998 YP_092228.1 putative mutants lead to the production of immature spores; RBL02507 YP_092229.1 RBL02503 YP_092230.1 RBL05752 YP_092231.1 similar to 5-formyltetrahydrofolate cyclo-ligase; RBL02501 YP_092232.1 possible ribosomal protein L33; in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_092233.1 RBL02499 YP_092234.1 RBL02498 YP_092235.1 RBL02497 YP_092236.1 similar to proteins from B. subtilis; RBL02496 YP_092237.1 phosphate ABC transporter (ATP-binding protein); ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_092238.1 phosphate ABC transporter (ATP-binding protein); ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_092239.1 phosphate ABC transporter (permease); RBL02493 YP_092240.1 phosphate ABC transporter (permease); RBL02492 YP_092241.1 phosphate ABC transporter (binding protein); RBL02491 YP_092242.1 penicillin-binding protein 2A (spore outgrowth); RBL02490 YP_092243.1 RBL02488 YP_092244.1 superoxide dismutase; RBL02487 YP_092245.1 RBL02485 YP_092246.1 RBL04853 YP_092247.1 RBL03936 YP_092248.1 similar to peptidoglycan acetylation; catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_092249.1 RBL03932 YP_092250.1 RBL03931 YP_092251.1 zinc uptake transcriptional repressor; RBL03930 YP_092252.1 similar to ABC transporter (permease); RBL03929 YP_092253.1 putative ABC transporter (ATP-binding protein); RBL03928 YP_092254.1 RBL05753 YP_092255.1 RBL05754 YP_092256.1 RBL05550 YP_092257.1 similar to endonuclease IV; Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_092258.1 similar to ATP-dependent RNA helicase; RBL03925 YP_092259.1 RBL03923 YP_092260.1 similar to penicillin tolerance; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_092261.1 RBL03920 YP_092262.1 RBL03919 YP_092263.1 putative endonuclease V; RBL04856 YP_092264.1 similar to putative endonuclease; RBL03918 YP_092265.1 RBL04857 YP_092266.1 RBL03917 YP_092267.1 RBL04858 YP_092268.1 RBL04859 YP_092269.1 RBL04860 YP_092270.1 RBL04861 YP_092271.1 RBL04862 YP_092272.1 similar to proteins from B. subtilis; RBL03916 YP_092273.1 similar to proteins from B. subtilis; RBL04863 YP_092274.1 RBL03915 YP_092275.1 cytochrome c550; RBL03914 YP_092276.1 RNA polymerase major sigma factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_092277.1 synthesizes RNA primers at the replication forks YP_092278.1 RBL03911 YP_092279.1 RBL03910 YP_092280.1 RBL03909 YP_092281.1 glycyl-tRNA synthetase (beta subunit); glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_092282.1 glycyl-tRNA synthetase (alpha subunit); glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_092283.1 DNA repair and homologous recombination; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_092284.1 GTP-binding protein; Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_092285.1 cytidine/deoxycytidine deaminase; RBL03904 YP_092286.1 diacylglycerol kinase; RBL03903 YP_092287.1 RBL03902 YP_092288.1 RBL03901 YP_092289.1 phosphate starvation-induced protein; RBL03899 YP_092290.1 similar to stage IV sporulation protein; RBL04864 YP_092291.1 RBL02644 YP_092292.1 RBL04865 YP_092293.1 RBL02646 YP_092294.1 RBL04866 YP_092295.1 RBL04867 YP_092296.1 ribosomal protein S21; a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_092297.1 similar to Na+/Pi cotransporter; RBL01106 YP_092298.1 close homolog to Dra deoxyribose-phosphate aldolase; catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_092299.1 RBL01108 YP_092300.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_092301.1 similar to ribosomal protein L11 methyltransferase; methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_092302.1 heat-shock protein (activation of DnaK); chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_092303.1 class I heat-shock protein (molecular chaperone); heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_092304.1 heat-shock protein (activation of DnaK); with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_092305.1 transcriptional repressor of class I heat-shock genes; Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_092306.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_092307.1 GTP-binding protein; binds to the ribosome on the universally-conserved alpha-sarcin loop YP_092308.1 RBL01540 YP_092309.1 required for dissolution of the septal cell wall; RBL04870 YP_092310.1 spore protease (degradation of SASPs); Initiates the rapid degradation of small, acid-soluble proteins during spore germination YP_092311.1 ribosomal protein S20 (BS20); binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_092312.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_092313.1 RBL04873 YP_092314.1 late competence operon required for DNA binding and uptake; RBL00676 YP_092315.1 late competence operon required for DNA binding and uptake; RBL03468 YP_092316.1 exogenous DNA-binding protein; RBL03470 YP_092317.1 non-essential gene for competence; may be involved in regulation of competence genes YP_092318.1 RBL03472 YP_092319.1 RBL03474 YP_092320.1 RBL03475 YP_092321.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_092322.1 RBL04874 YP_092323.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_092324.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_092325.1 RBL03479 YP_092326.1 developmental checkpoint coupling sporulation initiation to replication initiation; RBL04875 YP_092327.1 RBL03480 YP_092328.1 similar to antibiotic resistance protein; RBL03481 YP_092329.1 RBL03482 YP_092330.1 similar to formate dehydrogenase; RBL03485 YP_092331.1 similar to proteins from B. subtilis; RBL04876 YP_092332.1 RBL04877 YP_092333.1 RNA polymerase sporulation mother cell-specific (late) sigma factor (sigma-K C-terminal half); sigma-28; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell after engulfment YP_092334.1 RBL03488 YP_092335.1 RBL03489 YP_092336.1 putative RNA polymerase sigma-K factor, fragment 1; RBL05551 YP_092337.1 putative RNA polymerase sigma factor precursor; RBL04879 YP_092338.1 putative alanyl-tRNA synthetase; RBL03491 YP_092339.1 putative amino acid aldolase or racemase; RBL03492 YP_092340.1 putative translation initiation inhibitor; RBL03493 YP_092341.1 similar to asparaginase; RBL03494 YP_092342.1 similar to asparaginase; RBL05756 YP_092343.1 putative threonine synthase; RBL03495 YP_092344.1 RBL03496 YP_092345.1 two-component response regulator involved in C4-dicarboxylate transport; RBL03497 YP_092346.1 polymerase sigma-K factor; RBL03498 YP_092347.1 RBL03499 YP_092348.1 transcriptional activator of the bmrUR operon; RBL03500 YP_092349.1 putative hydrolase; RBL03501 YP_092350.1 putative flavoprotein reductase; RBL03502 YP_092351.1 putative two-component response regulator involved in degradative enzyme and competence regulation; RBL03503 YP_092352.1 putative two-component sensor histidine kinase involved in degradative enzyme and competence regulation; RBL03504 YP_092353.1 similar to thioredoxin; RBL04880 YP_092354.1 RBL03505 YP_092355.1 RBL04881 YP_092356.1 RBL03506 YP_092357.1 similar to proteins from B. subtilis; RBL03507 YP_092358.1 RBL03508 YP_092359.1 RBL04882 YP_092360.1 putative S-adenosylmethionine-dependent methyltransferase; RBL03509 YP_092361.1 RBL03510 YP_092362.1 RBL05554 YP_092363.1 RBL05757 YP_092364.1 putative ABC transporter permease protein; RBL03511 YP_092365.1 RBL03512 YP_092366.1 RBL04884 YP_092367.1 putative delta-aminolevulinic acid dehydratase; RBL05555 YP_092368.1 6-phospho-3-hexuloisomerase; RBL03513 YP_092369.1 3-hexulose-6-phosphate synthase; RBL03514 YP_092370.1 positive regulator of hxlAB expression; RBL04887 YP_092371.1 membrane phospholipid desaturase; RBL03516 YP_092372.1 similar to two-component sensor histidine kinase [YocG]; RBL03517 YP_092373.1 similar to two-component response regulator [YocF]; RBL03518 YP_092374.1 similar to thioredoxin reductase; RBL03519 YP_092375.1 putative oligopeptide transporter putative substrate binding domain; RBL03520 YP_092376.1 putative oligopeptide ABC transporter, permease protein; RBL03521 YP_092377.1 putative oligopeptide transport system permease protein; RBL03522 YP_092378.1 putative dipeptide transport ATP-binding protein; RBL03523 YP_092379.1 putative dipeptide transport ATP-binding protein; RBL03524 YP_092380.1 similar to multidrug-efflux transporter regulator; RBL03525 YP_092381.1 putative cation efflux pump; RBL03526 YP_092382.1 putative transcriptional regulator, AraC family; RBL03527 YP_092383.1 putative oxidoreductase protein; RBL03528 YP_092384.1 putative phosphatase; RBL03529 YP_092385.1 putative lipase/esterase; RBL03530 YP_092386.1 cytochrome P450-like enzyme; RBL03531 YP_092387.1 RBL03532 YP_092388.1 RBL00190 YP_092389.1 similar to 3-oxoacyl- acyl-carrier protein reductase; RBL00189 YP_092390.1 levanase; RBL00188 YP_092391.1 PTS fructose-specific enzyme IID component; RBL00187 YP_092392.1 PTS fructose-specific enzyme IIC component; RBL00186 YP_092393.1 PTS fructose-specific enzyme IIB component; RBL00185 YP_092394.1 PTS fructose-specific enzyme IIA component; RBL00184 YP_092395.1 transcriptional activator of the levanase operon; RBL00183 YP_092396.1 RBL00182 YP_092397.1 RBL05022 YP_092398.1 putative chloramphenicol acetyltransferase; RBL00181 YP_092399.1 methylphosphotriester-DNA alkyltransferase / transcriptional activator of the adaAB operon; RBL00180 YP_092400.1 O6-methylguanine-DNA methyltransferase; RBL00178 YP_092401.1 similar to plant metabolite dehydrogenase; RBL00176 YP_092402.1 similar to antibiotic resistance protein; RBL00175 YP_092403.1 RBL05023 YP_092404.1 RBL00174 YP_092405.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_092406.1 RBL00172 YP_092407.1 RBL00171 YP_092408.1 similar to transcriptional regulator (LysR family); RBL00170 YP_092409.1 similar to antibiotic resistance protein; RBL00169 YP_092410.1 RBL00168 YP_092411.1 similar to cytochrome P450 / NADPH-cytochrome P450 reductase; RBL00167 YP_092412.1 similar to transcriptional regulator (TetR/AcrR family); RBL00164 YP_092413.1 putative cell wall-associated protease precursor; RBL00163 YP_092414.1 putative methyltransferase; RBL00161 YP_092415.1 RBL00158 YP_092416.1 similar to cystathionine gamma-synthase; catalyzes the formation of L-homocysteine from cystathionine YP_092417.1 similar to cysteine synthase; RBL00156 YP_092418.1 methylthioadenosine nucleosidase; enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_092419.1 RBL00152 YP_092420.1 RBL05024 YP_092421.1 RBL00150 YP_092422.1 similar to penicillin-binding protein; RBL00148 YP_092423.1 transcription elongation factor; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_092424.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_092425.1 similar to protease; RBL00143 YP_092426.1 similar to protease; RBL00142 YP_092427.1 similar to caffeoyl-CoA O-methyltransferase; RBL00141 YP_092428.1 similar to folate metabolism; RBL00140 YP_092429.1 RBL05025 YP_092430.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_092431.1 RBL05026 YP_092432.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_092433.1 RBL00135 YP_092434.1 RBL05027 YP_092435.1 RBL00134 YP_092436.1 similar to exodeoxyribonuclease V alpha subunit; RBL00132 YP_092437.1 RBL00131 YP_092438.1 probable tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase; catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_092439.1 similar to NifS protein homolog; RBL00129 YP_092440.1 RBL00128 YP_092441.1 RBL05028 YP_092442.1 RBL05029 YP_092443.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_092444.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_092445.1 RBL05558 YP_092446.1 similar to N-acetylmuramoyl-L-alanine amidase; RBL05758 YP_092447.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_092448.1 GTP pyrophosphokinase (stringent response); RBL00055 YP_092449.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_092450.1 similar to single-strand DNA-specific exonuclease; RBL05560 YP_092451.1 RBL04820 YP_092452.1 protein-export membrane protein; part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_092453.1 RBL04819 YP_092454.1 involved in spore cortex synthesis; RBL02187 YP_092455.1 similar to proteins from B. subtilis; RBL02186 YP_092456.1 RBL04818 YP_092457.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_092458.1 tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_092459.1 S-adenosylmethionine tRNA ribosyltransferase; Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_092460.1 RBL04816 YP_092461.1 Holliday junction DNA helicase; promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_092462.1 Holliday junction DNA helicase; plays an essential role in ATP-dependent branch migration of the Holliday junction YP_092463.1 forespore regulator of the sigma-K checkpoint; RBL02180 YP_092464.1 RBL02179 YP_092465.1 small acid-soluble spore protein (minor); SASP H; spore coat; expressed in forespore compartment YP_092466.1 RBL02178 YP_092467.1 RBL02177 YP_092468.1 RBL04814 YP_092469.1 RBL04813 YP_092470.1 similar to spore coat protein; RBL02174 YP_092471.1 spore cortex protein; RBL02173 YP_092472.1 morphogenetic protein associated with SpoVID; RBL02171 YP_092473.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_092474.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_092475.1 catalyzes the formation of oxaloacetate from L-aspartate YP_092476.1 required for NAD biosynthesis; catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_092477.1 similar to transcriptional regulator; RBL00731 YP_092478.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_092479.1 chorismate mutase; RBL00729 YP_092480.1 GTP-binding protein involved in initiation of sporulation (Spo0A activation); essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_092481.1 sporulation initiation phosphotransferase; RBL00726 YP_092482.1 ribosomal protein L27 (BL24); involved in the peptidyltransferase reaction during translation YP_092483.1 RBL05997 YP_092484.1 ribosomal protein L21 (BL20); RBL05996 YP_092485.1 membrane metalloprotease required for the processing of pro-sigma-K to active sigma-K; RBL02558 YP_092486.1 inhibition of SpoIVFB; RBL02557 YP_092487.1 RBL02556 YP_092488.1 putative transcriptional regulator; RBL02555 YP_092489.1 cell-division inhibitor (septum placement); RBL02554 YP_092490.1 cell-division inhibitor (septum placement); blocks the formation of polar Z-ring septums YP_092491.1 cell-shape determining protein; RBL02551 YP_092492.1 cell-shape determining protein; in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_092493.1 cell-shape determining protein; functions in MreBCD complex in some organisms YP_092494.1 probable DNA repair protein; Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_092495.1 septum formation; Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_092496.1 spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment; RBL04806 YP_092497.1 late competence protein required for processing and translocation of ComGC, ComGD, ComGE, ComGG; RBL00009 YP_092498.1 folyl-polyglutamate synthetase; RBL00010 YP_092499.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_092500.1 RBL05564 YP_092501.1 RBL00014 YP_092502.1 required for assembly of the spore coat; RBL00016 YP_092503.1 glutamate-1-semialdehyde 2,1-aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_092504.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_092505.1 uroporphyrinogen III cosynthase; RBL00020 YP_092506.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_092507.1 negative effector of the concentration of HemA; RBL00023 YP_092508.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_092509.1 RBL00025 YP_092510.1 similar to GTP-binding protein; binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_092511.1 class III heat-shock ATP-dependent protease; RBL00027 YP_092512.1 Lon-like ATP-dependent protease; RBL00028 YP_092513.1 ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); binds and unfolds substrates as part of the ClpXP protease YP_092514.1 trigger factor (prolyl isomerase); Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_092515.1 RBL00037 YP_092516.1 3-isopropylmalate dehydratase (small subunit); catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_092517.1 3-isopropylmalate dehydratase (large subunit); dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_092518.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_092519.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_092520.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_092521.1 acetolactate synthase (small subunit); with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_092522.1 acetolactate synthase (large subunit); catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_092523.1 putative branched-chain amino acid aminotransferase; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_092524.1 RBL05995 YP_092525.1 glutamate dehydrogenase (major); converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_092526.1 RBL04804 YP_092527.1 RBL05566 YP_092528.1 putative phage PBSX protein; RBL04803 YP_092529.1 similar to phage-related terminase large subunit; RBL01006 YP_092530.1 RBL01007 YP_092531.1 RBL04802 YP_092532.1 RBL05567 YP_092533.1 RBL01009 YP_092534.1 RBL04801 YP_092535.1 putative modification methylase alpha subunit; RBL01010 YP_092536.1 RBL01011 YP_092537.1 RBL04800 YP_092538.1 putative ABC transporter (binding protein); RBL01012 YP_092539.1 putative response regulator aspartate phosphatase; RBL01013 YP_092540.1 RBL05759 YP_092541.1 RBL04799 YP_092542.1 RBL05760 YP_092543.1 RBL01014 YP_092544.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_092545.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_092546.1 germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa); RBL01017 YP_092547.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_092548.1 similar to transcriptional regulator (MarR family); RBL01019 YP_092549.1 transcriptional regulator required for the expression of late spore coat genes; RBL04798 YP_092550.1 putative oxidoreductase protein; RBL03779 YP_092551.1 RBL03778 YP_092552.1 succinate dehydrogenase (iron-sulfur protein); part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_092553.1 succinate dehydrogenase (flavoprotein subunit); part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_092554.1 succinate dehydrogenase (cytochrome b558 subunit); RBL03773 YP_092555.1 RBL03772 YP_092556.1 aspartokinase II (alpha and beta subunits); catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation YP_092557.1 excinuclease ABC (subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_092558.1 thioredoxin; RBL03767 YP_092559.1 electron transfer flavoprotein (alpha subunit); RBL03766 YP_092560.1 electron transfer flavoprotein (beta subunit); RBL03765 YP_092561.1 similar to 3-hydroxbutyryl-CoA dehydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_092562.1 similar to transcriptional regulator (TetR/AcrR family); RBL03763 YP_092563.1 long chain acyl-CoA synthetase; RBL03762 YP_092564.1 RBL03761 YP_092565.1 probable DNA mismatch repair protein; MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_092566.1 similar to DNA polymerase beta; RBL03757 YP_092567.1 RBL05569 YP_092568.1 RBL05570 YP_092569.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_092570.1 RBL00347 YP_092571.1 RBL00346 YP_092572.1 putative ABC transporter, ATP-binding protein; RBL00345 YP_092573.1 RBL05571 YP_092574.1 phenylalanyl-tRNA synthetase (beta subunit); catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_092575.1 phenylalanyl-tRNA synthetase (alpha subunit); catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_092576.1 similar to rRNA methylase; RBL05572 YP_092577.1 small acid-soluble spore protein (minor); RBL05573 YP_092578.1 carbon starvation-induced protein; RBL05574 YP_092579.1 RBL05575 YP_092580.1 alpha-L-arabinofuranosidase; RBL00915 YP_092581.1 L-arabinose transport (integral membrane protein); RBL00916 YP_092582.1 L-arabinose transport (integral membrane protein); RBL00917 YP_092583.1 L-arabinose transport (sugar-binding protein); RBL00918 YP_092584.1 L-arabinose operon; RBL00919 YP_092585.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_092586.1 L-ribulokinase; catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_092587.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_092588.1 close homolog to AbnA arabinan-endo 1,5-alpha-L-arabinase; RBL00923 YP_092589.1 similar to endo-1,4-beta-glucanase; RBL00924 YP_092590.1 RBL00925 YP_092591.1 RBL00927 YP_092592.1 ribosomal protein L20; binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_092593.1 ribosomal protein L35; RBL04923 YP_092594.1 initiation factor IF-3; IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_092595.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases YP_092596.1 negatively regulates murein hydrolase activity YP_092597.1 close homolog to PhoD phosphodiesterase/alkaline phosphatase; RBL00935 YP_092598.1 two-component response regulator involved in the rate of autolysis; RBL00936 YP_092599.1 two-component sensor histidine kinase involved in the rate of autolysis; RBL00937 YP_092600.1 RBL05578 YP_092601.1 RBL00939 YP_092602.1 threonyl-tRNA synthetase (major); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_092603.1 RBL00945 YP_092604.1 RBL00946 YP_092605.1 primosome component (helicase loader); Primosomal protein that may act to load helicase DnaC during DNA replication YP_092606.1 initiation of chromosome replication / membrane attachment protein; RBL00950 YP_092607.1 RBL04924 YP_092608.1 RBL04926 YP_092609.1 S-adenosylmethionine decarboxylase; Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_092610.1 NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis YP_092611.1 pectate lyase; RBL01876 YP_092612.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_092613.1 RBL01878 YP_092614.1 formamidopyrimidine-DNA glycosidase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_092615.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_092616.1 two-component sensor histidine kinase involved in phosphate regulation; RBL01881 YP_092617.1 two-component response regulator involved in phosphate regulation; RBL01882 YP_092618.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_092619.1 Converts isocitrate to alpha ketoglutarate YP_092620.1 citrate synthase II (major); catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_092621.1 RBL01888 YP_092622.1 RBL01890 YP_092623.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_092624.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_092625.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_092626.1 acetyl-CoA carboxylase (alpha subunit); catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_092627.1 acetyl-CoA carboxylase (beta subunit); catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_092628.1 similar to malate dehydrogenase; RBL01900 YP_092629.1 DNA polymerase III (alpha subunit); catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria YP_092630.1 RBL01902 YP_092631.1 RBL01903 YP_092632.1 RBL04929 YP_092633.1 RBL01904 YP_092634.1 RBL05579 YP_092635.1 RBL05763 YP_092636.1 transcriptional repressor of padC; RBL03957 YP_092637.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_092638.1 similar to 3-oxoacyl- acyl-carrier protein reductase; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_092639.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_092640.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_092641.1 molybdopterin precursor biosynthesis; RBL01197 YP_092642.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_092643.1 RBL01199 YP_092644.1 probable thiol peroxidase; antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_092645.1 RBL04486 YP_092646.1 RBL01153 YP_092647.1 RBL01152 YP_092648.1 putative signal peptide peptidase required for efficient processing of pre-proteins; RBL01151 YP_092649.1 catalyzes the phosphorylation of NAD to NADP YP_092650.1 RBL01148 YP_092651.1 similar to multidrug resistance protein; RBL01147 YP_092652.1 similar to transcriptional regulator (MarR family); RBL05580 YP_092653.1 similar to acetate-CoA ligase; RBL03036 YP_092654.1 close homolog to SspB small acid-soluble spore protein (major beta-type SASP); RBL05021 YP_092655.1 similar to thiamin biosynthesis; Required for the synthesis of the thiazole moiety YP_092656.1 NifS protein homolog; RBL03034 YP_092657.1 branched-chain amino acid transporter; RBL03031 YP_092658.1 putative transposase; RBL06002 YP_092659.1 putative transposase; RBL05994 YP_092660.1 negative regulator of FtsZ ring formation; acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_092661.1 histidinol phosphate phosphatase; catalyzes the formation of L-histidinol from L-histidinol phosphate YP_092662.1 RBL03026 YP_092663.1 RBL03025 YP_092664.1 similar to two-component sensor histidine kinase; RBL03024 YP_092665.1 ribosomal protein S4 (BS4); primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_092666.1 RBL05768 YP_092667.1 RBL05581 YP_092668.1 RBL03022 YP_092669.1 RBL03021 YP_092670.1 transcriptional regulator involved in repression of glyA transcription and KinB-dependent sporulation; RBL03020 YP_092671.1 RBL05582 YP_092672.1 tyrosyl-tRNA synthetase (major); catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_092673.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_092674.1 acetoin dehydrogenase; RBL03016 YP_092675.1 acetoin dehydrogenase; RBL03015 YP_092676.1 acetoin dehydrogenase; RBL03013 YP_092677.1 similar to motility protein; Homolog of MotB, appears to be involved in motility on surfaces or under specific ionic conditions. With MotP (a Mot A homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_092678.1 similar to flagellar motor apparatus; Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_092679.1 transcriptional regulator mediating carbon catabolite repression; RBL03007 YP_092680.1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase / chorismate mutase-isozyme 3; catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_092681.1 RBL03005 YP_092682.1 similar to general stress protein; RBL03004 YP_092683.1 similar to general stress protein; RBL03003 YP_092684.1 similar to general stress protein; RBL03002 YP_092685.1 UDP-N-acetylmuramate-alanine ligase; Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_092686.1 similar to DNA translocase stage III sporulation protein (SpoIIIE); RBL03000 YP_092687.1 similar to phenylalanyl-tRNA synthetase (beta subunit); RBL02997 YP_092688.1 RBL02996 YP_092689.1 similar to thioredoxin H1; RBL02995 YP_092690.1 RBL05583 YP_092691.1 similar to endo-1,4-beta-glucanase; RBL05769 YP_092692.1 RBL05770 YP_092693.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_092694.1 RBL00991 YP_092695.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_092696.1 RBL05017 YP_092697.1 RBL03721 YP_092698.1 pullulanase; RBL03720 YP_092699.1 RBL03718 YP_092700.1 RBL03717 YP_092701.1 similar to ABC transporter (permease); RBL03716 YP_092702.1 similar to cysteine synthase; RBL03715 YP_092703.1 RBL05016 YP_092704.1 RBL03714 YP_092705.1 similar to Xaa-His dipeptidase; divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_092706.1 RBL03433 YP_092707.1 similar to transcriptional regulator (DeoR family); RBL04821 YP_092708.1 putative pseudouridylate synthase; RBL03434 YP_092709.1 similar to spore cortex protein; RBL03435 YP_092710.1 RBL03436 YP_092711.1 glycine betaine transporter; RBL03437 YP_092712.1 RBL04822 YP_092713.1 RBL04823 YP_092714.1 response regulator aspartate phosphatase; RBL04824 YP_092715.1 RBL03391 YP_092716.1 similar to proteins from B. subtilis; RBL03392 YP_092717.1 RBL03393 YP_092718.1 RBL04825 YP_092719.1 RBL03396 YP_092720.1 RBL03398 YP_092721.1 similar to transcriptional regulator (AraC/XylS family); RBL03401 YP_092722.1 similar to lipoprotein; RBL03402 YP_092723.1 similar to ABC transporter (permease); RBL03403 YP_092724.1 RBL03404 YP_092725.1 RBL03405 YP_092726.1 putative amino acid permease; RBL03406 YP_092727.1 similar to transcriptional regulator (LysR family); RBL03407 YP_092728.1 RBL03408 YP_092729.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_092730.1 RBL04826 YP_092731.1 similar to multidrug resistance protein; RBL04828 YP_092732.1 RBL04829 YP_092733.1 putative ABC transporter, fragment 2; RBL01781 YP_092734.1 RBL01782 YP_092735.1 similar to ABC transporter (ATP-binding protein); RBL01783 YP_092736.1 RBL01784 YP_092737.1 similar to ABC transporter (ATP-binding protein); RBL01785 YP_092738.1 similar to transcriptional regulator (GntR family); RBL01786 YP_092739.1 RBL01787 YP_092740.1 RBL01788 YP_092741.1 RBL01789 YP_092742.1 H+/glutamate symport protein; RBL01790 YP_092743.1 RBL01791 YP_092744.1 similar to lysophospholipase; RBL01792 YP_092745.1 similar to ferripyochelin binding protein; RBL01793 YP_092746.1 RBL01794 YP_092747.1 putative glucosyl transferase; RBL01796 YP_092748.1 asparagine synthetase; RBL01799 YP_092749.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_092750.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_092751.1 putative amino acid transporter; RBL01803 YP_092752.1 RBL04830 YP_092753.1 RBL01804 YP_092754.1 RBL01805 YP_092755.1 similar to anion transport ABC transporter (ATP-binding protein); RBL01806 YP_092756.1 similar to ABC transporter (permease); RBL01808 YP_092757.1 RBL01809 YP_092758.1 RBL01810 YP_092759.1 similar to autolytic amidase; RBL01811 YP_092760.1 stress- and starvation-induced gene controlled by sigma-B; RBL01812 YP_092761.1 RBL01813 YP_092762.1 probable autoinducer-2 production protein; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_092763.1 similar to alpha-hemolysin; RBL04832 YP_092764.1 similar to carbonic anhydrase; RBL04833 YP_092765.1 putative ABC transporter (amino acid permease); RBL04834 YP_092766.1 similar to ABC transporter (binding protein); RBL03389 YP_092767.1 similar to ribosomal protein; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_092768.1 similar to cytochrome d oxidase subunit; RBL03388 YP_092769.1 similar to ubiquinol oxidase subunit II; RBL03387 YP_092770.1 RBL05117 YP_092771.1 O-succinylbenzoate-CoA synthase; RBL03386 YP_092772.1 O-succinylbenzoic acid-CoA ligase; converts O-succinylbenzoate to O-succinylbenzoyl-CoA YP_092773.1 dihydroxynapthoic acid synthetase; catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_092774.1 similar to prolyl aminopeptidase; RBL03381 YP_092775.1 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase / 2-oxoglutarate decarboxylase; SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_092776.1 synthesizes isochorismate acid from chorismate YP_092777.1 probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_092778.1 RBL00351 YP_092779.1 glycogen phosphorylase; RBL00353 YP_092780.1 starch (bacterial glycogen) synthase; catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_092781.1 required for glycogen biosynthesis; RBL00355 YP_092782.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_092783.1 1,4-alpha-glucan branching enzyme; catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_092784.1 RBL06003 YP_092785.1 RBL05772 YP_092786.1 putative transcriptional regulator, fragment 2; RBL05774 YP_092787.1 RBL05648 YP_092788.1 RBL01454 YP_092789.1 RBL01453 YP_092790.1 response regulator aspartate phosphatase; RBL01452 YP_092791.1 RBL05775 YP_092792.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_092793.1 similar to potassium uptake protein; RBL01449 YP_092794.1 putative oligoendopeptidase; RBL01448 YP_092795.1 RBL01447 YP_092796.1 RBL01446 YP_092797.1 RBL01444 YP_092798.1 alcohol dehydrogenase; RBL01443 YP_092799.1 glycine betaine aldehyde dehydrogenase; RBL01441 YP_092800.1 RBL01438 YP_092801.1 putative high affinity choline transporter; RBL01437 YP_092802.1 RBL01436 YP_092803.1 similar to alanine racemase; RBL01435 YP_092804.1 RBL01434 YP_092805.1 RBL05776 YP_092806.1 RBL04892 YP_092807.1 RBL01432 YP_092808.1 RBL01430 YP_092809.1 RBL01429 YP_092810.1 RBL01428 YP_092811.1 RBL01427 YP_092812.1 RBL04891 YP_092813.1 RBL01425 YP_092814.1 similar to proteins from B. subtilis; RBL01424 YP_092815.1 RBL01422 YP_092816.1 RBL01421 YP_092817.1 similar to bacitracin resistance protein (undecaprenol kinase); BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell YP_092818.1 RBL01419 YP_092819.1 RBL05778 YP_092820.1 RBL01417 YP_092821.1 similar to general stress protein; RBL01416 YP_092822.1 close homolog to McpA methyl-accepting chemotaxis protein; RBL01415 YP_092823.1 methyl-accepting chemotaxis protein; RBL01414 YP_092824.1 close homolog to McpA methyl-accepting chemotaxis protein; RBL01413 YP_092825.1 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links YP_092826.1 similar to 2-nitropropane dioxygenase; RBL01411 YP_092827.1 RBL01409 YP_092828.1 similar to exo-alpha-1,4-glucosidase; RBL01408 YP_092829.1 similar to transcriptional regulator (TetR/AcrR family); RBL01407 YP_092830.1 RBL01406 YP_092831.1 putative sugar hydrolase; RBL01405 YP_092832.1 similar to hemolysin; RBL01404 YP_092833.1 RBL01403 YP_092834.1 RBL04890 YP_092835.1 RBL01402 YP_092836.1 similar to potassium channel protein; RBL01401 YP_092837.1 RBL01400 YP_092838.1 RBL01399 YP_092839.1 RBL01398 YP_092840.1 putative acetyltransferase; RBL01397 YP_092841.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_092842.1 RBL05779 YP_092843.1 similar to NADH-dependent butanol dehydrogenase; RBL01394 YP_092844.1 RBL04889 YP_092845.1 similar to polyribonucleotide nucleotidyltransferase; induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation YP_092846.1 putative alanine transaminase; RBL01392 YP_092847.1 transcriptional regulator of the alaRT operon; RBL01391 YP_092848.1 similar to dihydrolipoamide S-acetyltransferase; RBL01390 YP_092849.1 RBL05780 YP_092850.1 RBL01387 YP_092851.1 aminotransferase; RBL01386 YP_092852.1 RBL05781 YP_092853.1 activator of KinB in the initiation of sporulation; RBL01383 YP_092854.1 inhibitor of the KinA pathway to sporulation; inhibitor of the KinA pathway of sporulation YP_092855.1 similar to multidrug-efflux transporter; RBL01381 YP_092856.1 penicillin-binding protein 4; RBL01380 YP_092857.1 RBL01379 YP_092858.1 RBL01378 YP_092859.1 similar to two-component sensor histidine kinase [YufM]; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_092860.1 similar to two-component response regulator [YufL]; RBL01375 YP_092861.1 putative ABC transporter, fragment; RBL05782 YP_092862.1 phosphatidylserine synthase; RBL02886 YP_092863.1 similar to alkaline phosphatase; RBL02887 YP_092864.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_092865.1 putative transposase; RBL05992 YP_092866.1 putative transposase; RBL06004 YP_092867.1 Na+/malate symporter; RBL02890 YP_092868.1 RBL05476 YP_092869.1 multiple resistance and pH homeostasis (Na+/H+ antiporter); subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_092870.1 multiple resistance and pH homeostasis; subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_092871.1 multiple resistance and pH homeostasis; subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_092872.1 multiple resistance and pH homeostasis; subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_092873.1 multiple resistance and pH homeostasis; subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_092874.1 multiple resistance and pH homeostasis; subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_092875.1 multiple resistance and pH homeostasis; subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_092876.1 RBL02897 YP_092877.1 two-component response regulator of late competence genes / surfactin production; RBL02898 YP_092878.1 two-component sensor histidine kinase involved in early competence; RBL02899 YP_092879.1 putative transposase; RBL05993 YP_092880.1 putative transposase; RBL06005 YP_092881.1 putative two-component sensor histidine kinase involved in early competence; RBL02901 YP_092882.1 competence pheromone precursor; RBL05787 YP_092883.1 transcriptional regulator of late competence operon (comG) and surfactin expression (srfA); RBL02902 YP_092884.1 degradative enzyme production; RBL05475 YP_092885.1 RBL02903 YP_092886.1 RBL02904 YP_092887.1 similar to nicotinate phosphoribosyltransferase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_092888.1 similar to pyrazinamidase/nicotinamidase; RBL02906 YP_092889.1 RBL02907 YP_092890.1 RBL05474 YP_092891.1 similar to proteins from B. subtilis; RBL05473 YP_092892.1 RBL02909 YP_092893.1 RBL02910 YP_092894.1 putative lipase/esterase; RBL02911 YP_092895.1 putative lipase precursor; RBL02912 YP_092896.1 RBL02913 YP_092897.1 similar to sepiapterin reductase; RBL02914 YP_092898.1 RBL02916 YP_092899.1 RBL02917 YP_092900.1 RBL02921 YP_092901.1 RBL02923 YP_092902.1 RBL05472 YP_092903.1 RBL05471 YP_092904.1 putative Na(+)-linked D-alanine glycine permease; RBL02924 YP_092905.1 similar to proteins from B. subtilis; RBL02925 YP_092906.1 L-alanine dehydrogenase; RBL02926 YP_092907.1 RBL05470 YP_092908.1 similar to sulfite oxidase; RBL02927 YP_092909.1 similar to biotin metabolism; RBL05469 YP_092910.1 RBL05468 YP_092911.1 similar to leucyl aminopeptidase; catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_092912.1 RBL00065 YP_092913.1 RBL00064 YP_092914.1 similar to proteins from B. subtilis; RBL00063 YP_092915.1 similar to proteins from B. subtilis; RBL05467 YP_092916.1 similar to NADH dehydrogenase; RBL00062 YP_092917.1 similar to thioredoxin reductase; RBL00061 YP_092918.1 RBL05466 YP_092919.1 similar to proteins from B. subtilis; RBL00059 YP_092920.1 RBL00057 YP_092921.1 probable diaminopimelate epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_092922.1 similar to Na+/nucleoside cotransporter; RBL05465 YP_092923.1 RBL05790 YP_092924.1 similar to NADH dehydrogenase; RBL00361 YP_092925.1 similar to proteins from B. subtilis; RBL00362 YP_092926.1 RBL05791 YP_092927.1 putative response regulator; RBL00363 YP_092928.1 phenolic acid decarboxylase; RBL00364 YP_092929.1 similar to spore coat protein; RBL05463 YP_092930.1 RBL00365 YP_092931.1 similar to NifU protein homolog; RBL05792 YP_092932.1 similar to acylaminoacyl-peptidase; RBL03109 YP_092933.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_092934.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_092935.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_092936.1 putative spore germination protein; RBL04135 YP_092937.1 RBL04136 YP_092938.1 similar to low temperature requirement C protein; RBL04137 YP_092939.1 similar to p-nitrophenyl phosphatase; RBL04138 YP_092940.1 RBL04139 YP_092941.1 RBL04141 YP_092942.1 RBL04142 YP_092943.1 probable lipoic acid synthetase; catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_092944.1 RBL04275 YP_092945.1 RBL05793 YP_092946.1 putative transporter; RBL04724 YP_092947.1 RBL04031 YP_092948.1 RBL04030 YP_092949.1 RBL04028 YP_092950.1 RBL04027 YP_092951.1 RBL04026 YP_092952.1 RBL04025 YP_092953.1 putative transcriptional regulator; RBL04024 YP_092954.1 RBL05462 YP_092955.1 similar to aspartate aminotransferase; RBL04023 YP_092956.1 similar to N-carbamyl-L-amino acid amidohydrolase; allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_092957.1 transcriptional regulator of puc genes; RBL04021 YP_092958.1 multidrug-efflux transporter; RBL04019 YP_092959.1 RBL05794 YP_092960.1 RBL05795 YP_092961.1 RBL05796 YP_092962.1 similar to ribonuclease; RBL02009 YP_092963.1 xanthine dehydrogenase; RBL02008 YP_092964.1 similar to glycine oxidase; RBL02007 YP_092965.1 putative permease; RBL02006 YP_092966.1 RBL02005 YP_092967.1 response regulator aspartate phosphatase; RBL02004 YP_092968.1 RBL02003 YP_092969.1 similar to NifU protein homolog; RBL02001 YP_092970.1 probable cysteine desulfurase; RBL02000 YP_092971.1 RBL01999 YP_092972.1 similar to ABC transporter (ATP-binding protein); RBL01997 YP_092973.1 cation-efflux system membrane protein; RBL05132 YP_092974.1 RBL02683 YP_092975.1 RBL02684 YP_092976.1 RBL02685 YP_092977.1 similar to ABC transporter (ATP-binding protein); RBL02686 YP_092978.1 RBL02687 YP_092979.1 similar to thioredoxin; RBL02688 YP_092980.1 RBL02689 YP_092981.1 RBL05797 YP_092982.1 probable glycine cleavage system protein H; part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_092983.1 similar to arsenate reductase; RBL04669 YP_092984.1 similar to butyryl-CoA dehydrogenase; RBL03940 YP_092985.1 similar to acetyl-CoA C-acyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_092986.1 similar to 3-hydroxyacyl-CoA dehydrogenase; RBL03937 YP_092987.1 RBL05135 YP_092988.1 RBL05136 YP_092989.1 RBL02720 YP_092990.1 RBL05798 YP_092991.1 RBL02717 YP_092992.1 similar to iron(III) dicitrate transport permease; RBL02716 YP_092993.1 similar to iron(III) dicitrate transport permease; RBL02715 YP_092994.1 similar to iron(III) dicitrate transport permease; RBL02713 YP_092995.1 similar to iron(III) dicitrate transport permease; RBL00804 YP_092996.1 RBL00805 YP_092997.1 similar to oligoendopeptidase; RBL00806 YP_092998.1 putative penicillin-binding protein 5* (D-alanyl-D-alanine carboxypeptidase); RBL00807 YP_092999.1 similar to retinol dehydrogenase; RBL01455 YP_093000.1 metalloregulation DNA-binding stress protein; RBL01456 YP_093001.1 similar to HtrA-like serine protease; RBL01457 YP_093002.1 two-component response regulator involved in the control of cellular responses to protein secretion stress; RBL01458 YP_093003.1 two-component sensor histidine kinase involved in the control of cellular responses to protein secretion stress; RBL01460 YP_093004.1 RBL05139 YP_093005.1 similar to proteins from B. subtilis; RBL01461 YP_093006.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_093007.1 RBL05140 YP_093008.1 germination response to L-alanine; RBL01466 YP_093009.1 germination response to L-alanine; RBL01467 YP_093010.1 germination response to L-alanine; RBL01468 YP_093011.1 RBL01469 YP_093012.1 similar to two-component response regulator [YvqE]; RBL01470 YP_093013.1 similar to two-component sensor histidine kinase [YvqC]; RBL01471 YP_093014.1 RBL01472 YP_093015.1 RBL01473 YP_093016.1 similar to proteins from B. subtilis; RBL01474 YP_093017.1 RBL01475 YP_093018.1 putative pectin methylesterase; RBL01476 YP_093019.1 RBL01477 YP_093020.1 putative acyl carrier protein reductase; RBL01478 YP_093021.1 RBL05799 YP_093022.1 putative alcohol dehydrogenase II; RBL01480 YP_093023.1 putative dihydrodipicolinate synthase; RBL01482 YP_093024.1 similar to iron transport system; RBL01483 YP_093025.1 similar to iron permease; RBL01484 YP_093026.1 similar to iron-binding protein; RBL01485 YP_093027.1 putative transcriptional regulator, GntR family; RBL04223 YP_093028.1 similar to ketoacyl-carrier protein reductase; RBL02546 YP_093029.1 RBL02545 YP_093030.1 putative transcriptional regulator of the alpha-acetolactate operon; RBL02544 YP_093031.1 putative polygalacturonase; RBL02542 YP_093032.1 altronate hydrolase; RBL02541 YP_093033.1 tagaturonate reductase; catalyzes the formation of D-tagaturonate from D-altronate YP_093034.1 transcriptional repressor of the hexuronate utilization operon; RBL02539 YP_093035.1 similar to Na+galactoside symporter; RBL02537 YP_093036.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_093037.1 similar to two-component sensor histidine kinase [YvrH]; RBL02535 YP_093038.1 similar to two-component response regulator [YvrG]; RBL02533 YP_093039.1 ferrichrome ABC transporter (ATP-binding protein); RBL02532 YP_093040.1 ferrichrome ABC transporter (permease); RBL02530 YP_093041.1 ferrichrome ABC transporter (permease); RBL02529 YP_093042.1 similar to ABC transporter (amino acid permease); RBL02528 YP_093043.1 RBL02526 YP_093044.1 RBL05800 YP_093045.1 RBL02525 YP_093046.1 RBL02524 YP_093047.1 putative ABC transporter (ATP-binding protein); RBL02522 YP_093048.1 similar to dehydrogenase; RBL02521 YP_093049.1 similar to fructokinase; RBL02520 YP_093050.1 similar to NifS protein homolog; RBL02519 YP_093051.1 RBL05801 YP_093052.1 RBL02517 YP_093053.1 RBL02515 YP_093054.1 RBL05802 YP_093055.1 RBL02286 YP_093056.1 thiol-disulfide oxidoreductase; RBL02285 YP_093057.1 thiol-disulfide oxidoreductase; RBL02284 YP_093058.1 similar to heavy metal-transporting ATPase; RBL02282 YP_093059.1 putative ABC transporter sugar binding protein; RBL01130 YP_093060.1 putative transporter; RBL01129 YP_093061.1 similar to sugar permease; RBL01127 YP_093062.1 putative alpha-glucosidase; catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_093063.1 putative sugar hydrolase; RBL01124 YP_093064.1 manganese ABC transporter (ATP-binding protein); RBL03114 YP_093065.1 manganese ABC transporter; RBL03115 YP_093066.1 manganese ABC transporter (membrane protein); RBL03117 YP_093067.1 putative transcriptional regulator; RBL03121 YP_093068.1 putative fructose 1-phosphate kinase; RBL03122 YP_093069.1 close homolog to FruA PTS fructose-specific enzyme IIABC component; RBL03123 YP_093070.1 putative phosphotransferase system (PTS) fructose-specific enzyme IIABC component; RBL03124 YP_093071.1 putative fructose-1,6-bisphosphate aldolase; catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_093072.1 similar to heavy metal-transporting ATPase; RBL03126 YP_093073.1 similar to mercuric transport protein; RBL05142 YP_093074.1 RBL03127 YP_093075.1 putative intracellular proteinase I; RBL03128 YP_093076.1 similar to transcriptional regulator (DeoR family); RBL03129 YP_093077.1 similar to rhamnulokinase; RBL03132 YP_093078.1 xylose isomerase; RBL03134 YP_093079.1 RBL03135 YP_093080.1 similar to sorbitol-6-phosphate 2-dehydrogenase; RBL03136 YP_093081.1 putative chloramphenicol resistance protein; RBL05143 YP_093083.1 similar to multidrug transporter; RBL05145 YP_093084.1 RBL05146 YP_093085.1 cytochrome P450-like enzyme; RBL04119 YP_093086.1 RBL04120 YP_093087.1 similar to proteins from B. subtilis; RBL04121 YP_093088.1 RBL04122 YP_093089.1 putative amidase; RBL04123 YP_093090.1 RBL04125 YP_093091.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_093092.1 RBL04127 YP_093093.1 putative two-component response regulator [YvrG]; RBL05805 YP_093094.1 RBL04128 YP_093095.1 RBL05806 YP_093096.1 oxalate decarboxylase; RBL04129 YP_093097.1 RBL04130 YP_093098.1 RBL04131 YP_093099.1 RBL04132 YP_093100.1 RBL05807 YP_093101.1 RBL05149 YP_093102.1 RBL05150 YP_093103.1 RBL05808 YP_093104.1 RBL04745 YP_093105.1 RBL05809 YP_093106.1 putative transposase; RBL06006 YP_093107.1 putative transposase; RBL06007 YP_093108.1 putative transcriptional repressor protein; RBL05812 YP_093109.1 RBL05813 YP_093110.1 RBL05814 YP_093111.1 RBL05815 YP_093112.1 RBL05816 YP_093113.1 RBL05817 YP_093114.1 N-acetylmuramoyl-L-alanine amidase cwlL precursor (Cell wall hydrolase) (Autolysin); RBL05818 YP_093115.1 RBL05819 YP_093116.1 RBL06008 YP_093117.1 RBL02749 YP_093118.1 putative phage PBSX protein; RBL02748 YP_093119.1 RBL02746 YP_093120.1 putative phage autolysin (amidase) homolog; RBL02744 YP_093121.1 RBL02743 YP_093122.1 putative phage tail protein; RBL02742 YP_093123.1 RBL05277 YP_093124.1 RBL02740 YP_093125.1 RBL02739 YP_093126.1 RBL05278 YP_093127.1 RBL02738 YP_093128.1 RBL02737 YP_093129.1 RBL05279 YP_093130.1 RBL02735 YP_093131.1 family serine protease, possible phage related; RBL02734 YP_093132.1 putative portal protein; RBL02733 YP_093133.1 RBL05821 YP_093134.1 putative terminase large subunit; RBL02732 YP_093135.1 putative phage terminase protein, small subunit; RBL02731 YP_093137.1 RBL02730 YP_093138.1 RBL05285 YP_093139.1 RBL02729 YP_093140.1 RBL02728 YP_093141.1 RBL05824 YP_093142.1 RBL05287 YP_093143.1 RBL02726 YP_093144.1 RBL02725 YP_093145.1 RBL02724 YP_093146.1 RBL02723 YP_093147.1 RBL05288 YP_093148.1 RBL05289 YP_093149.1 RBL05825 YP_093150.1 RBL05290 YP_093151.1 RBL05991 YP_093152.1 RBL02721 YP_093153.1 similar to integrase; RBL00667 YP_093154.1 tmRNA-binding protein; binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_093155.1 RBL00670 YP_093156.1 similar to carboxylesterase; RBL00671 YP_093157.1 preprotein translocase subunit; RBL05293 YP_093158.1 close homolog to Abh transcriptional regulator of transition state genes (AbrB-like); RBL05826 YP_093159.1 RBL05827 YP_093160.1 similar to immunity repressor protein; RBL04342 YP_093161.1 putative spore germination protein; RBL02947 YP_093162.1 glycine betaine/carnitine/choline ABC transporter (membrane protein); RBL02946 YP_093163.1 glycine betaine/carnitine/choline ABC transporter (osmoprotectant-binding protein); RBL02945 YP_093164.1 glycine betaine/carnitine/choline ABC transporter (membrane protein); RBL02944 YP_093165.1 glycine betaine/carnitine/choline ABC transporter (ATP-binding protein); RBL02943 YP_093166.1 similar to proteins from B. subtilis; RBL02942 YP_093167.1 RBL02941 YP_093168.1 RBL02940 YP_093169.1 RBL02939 YP_093170.1 RBL02938 YP_093171.1 putative iron(III) transporter binding protein; RBL02937 YP_093172.1 RBL04346 YP_093173.1 similar to proteins from B. subtilis; RBL05294 YP_093174.1 similar to proteins from B. subtilis; RBL05295 YP_093175.1 enolase; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_093176.1 phosphoglycerate mutase; catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_093177.1 triose phosphate isomerase; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_093178.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_093179.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_093180.1 transcriptional repressor of gapA; RBL03420 YP_093181.1 similar to alkanal monooxygenase; RBL03422 YP_093182.1 similar to amino acid permease; RBL03423 YP_093183.1 RBL05828 YP_093184.1 RBL03749 YP_093185.1 RBL03748 YP_093186.1 RBL03747 YP_093187.1 RBL03746 YP_093188.1 similar to glycolate oxidase; RBL03745 YP_093189.1 similar to transcriptional regulator (GntR family); RBL03744 YP_093190.1 similar to L-lactate permease; RBL03983 YP_093191.1 RNA polymerase sigma factor; RBL03985 YP_093192.1 RBL05229 YP_093193.1 similar to proteins from B. subtilis; RBL03986 YP_093194.1 similar to spore coat polysaccharide biosynthesis; RBL03988 YP_093195.1 similar to serine O-acetyltransferase; RBL03989 YP_093196.1 similar to UDP-galactose phosphate transferase; RBL03990 YP_093197.1 RBL03991 YP_093198.1 similar to 1,4-galactosyltransferase; RBL03992 YP_093199.1 RBL03993 YP_093200.1 similar to spore coat polysaccharide biosynthesis; RBL03994 YP_093201.1 similar to capsular polysaccharide biosynthesis; RBL03996 YP_093202.1 similar to glycosyltransferase; RBL03997 YP_093203.1 similar to glycosyltransferase; RBL03998 YP_093204.1 similar to capsular polysaccharide biosynthesis; RBL03999 YP_093205.1 similar to capsular polysaccharide biosynthesis; RBL04000 YP_093206.1 similar to capsular polysaccharide biosynthesis; RBL04001 YP_093207.1 similar to capsular polysaccharide biosynthesis; RBL04002 YP_093208.1 transcriptional activator of competence development and sporulation genes; RBL04003 YP_093209.1 similar to NAD(P)H oxidoreductase; RBL04004 YP_093210.1 putative glucarate transporter; RBL04005 YP_093211.1 RBL04006 YP_093212.1 putative pyridoxal phosphate biosynthetic protein; catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_093213.1 RBL04010 YP_093214.1 putative alkohol dehydrogenase; RBL05228 YP_093215.1 putative dihydrodipicolinate synthase; RBL04013 YP_093216.1 putative sigma-L-dependent transcriptional regulator; RBL05227 YP_093217.1 putative transcriptional regulator; RBL02378 YP_093218.1 similar to NADH-dependent flavin oxidoreductase; RBL02379 YP_093219.1 levansucrase; RBL02381 YP_093220.1 similar to levanase; RBL02382 YP_093221.1 RBL05226 YP_093222.1 ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_093223.1 RBL02101 YP_093224.1 RBL02100 YP_093225.1 RBL02099 YP_093226.1 similar to transporter; RBL02098 YP_093227.1 similar to carbonic anhydrase; RBL02096 YP_093228.1 similar to glycerate dehydrogenase; RBL02095 YP_093229.1 RBL02094 YP_093230.1 RBL02093 YP_093231.1 putative ribonuclease; RBL02092 YP_093232.1 similar to ribonuclease inhibitor; RBL05045 YP_093233.1 similar to N-hydroxyarylamine O-acetyltransferase; RBL02091 YP_093234.1 catabolite repression HPr-like protein; RBL05044 YP_093235.1 RBL02090 YP_093236.1 RBL02089 YP_093237.1 RBL02088 YP_093238.1 similar to mutator MutT protein; RBL02087 YP_093239.1 RBL02086 YP_093240.1 thioredoxin reductase; RBL02085 YP_093241.1 RBL02083 YP_093242.1 RBL03825 YP_093243.1 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_093244.1 HisF cyclase-like protein; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_093245.1 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_093246.1 amidotransferase; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_093247.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_093248.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_093249.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_093250.1 histidyl-tRNA synthetase; May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_093251.1 RBL05829 YP_093252.1 similar to pectate lyase; RBL03812 YP_093253.1 similar to O-acetyltransferase; RBL03811 YP_093254.1 P-Ser-HPr phosphatas; hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation YP_093255.1 RBL03807 YP_093256.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_093257.1 HPr kinase (phosphorylation of HPr and Crh proteins at Ser46); catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_093258.1 similar to transcriptional regulator (MarR family); RBL03804 YP_093259.1 similar to multidrug-efflux transporter; RBL03803 YP_093260.1 RBL03802 YP_093261.1 RBL03800 YP_093262.1 RBL05043 YP_093263.1 RBL03799 YP_093264.1 RBL05225 YP_093265.1 RBL05224 YP_093266.1 putative dioxygenase; RBL05830 YP_093267.1 RBL05042 YP_093268.1 excinuclease ABC (subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_093269.1 excinuclease ABC (subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_093270.1 RBL05040 YP_093271.1 RBL05039 YP_093272.1 RBL00746 YP_093273.1 RBL00745 YP_093274.1 similar to carboxy-terminal processing protease; RBL00744 YP_093275.1 similar to 3-isopropylmalate dehydrogenase; catalyzes the formation of oxaloglycolate from tartrate; also catalyzes the formation of pyruvate from malate and glycerate from tartrate YP_093276.1 putative cell wall-binding protein; RBL00741 YP_093277.1 cell-division protein; RBL00740 YP_093278.1 cell-division ATP-binding protein; RBL00738 YP_093279.1 cytochrome c551; RBL05038 YP_093280.1 RBL05037 YP_093281.1 peptide chain release factor 2; RBL03377 YP_093282.1 preprotein translocase subunit (ATPase); functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_093283.1 similar to sigma-54 modulating factor of gram-negative bacteria; RBL00331 YP_093284.1 RBL00330 YP_093285.1 flagellar protein; RBL05036 YP_093286.1 flagellar protein; flagellin specific chaperone YP_093287.1 flagellar hook-associated protein 2 (HAP2); involved in flagellin assembly YP_093288.1 similar to flagellar protein; possibly involved in flagella export YP_093289.1 flagellin protein; structural flagella protein YP_093290.1 affects carbohydrate metabolism; has regulatory role in many processes YP_093291.1 similar to proteins from B. subtilis; binds to flagellin and appears to stabilize flagellin during flagella assembly YP_093292.1 RBL00322 YP_093293.1 flagellar hook-associated protein 3 (HAP3); with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_093294.1 flagellar hook-associated protein 1 (HAP1); with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_093295.1 similar to flagellar protein; RBL00319 YP_093296.1 flagellin synthesis regulatory protein (anti-sigma factor); RBL05034 YP_093297.1 similar to flagellar protein; RBL00318 YP_093298.1 late competence gene; RBL00317 YP_093299.1 late competence gene; RBL05033 YP_093300.1 late competence protein required for DNA uptake; RBL00315 YP_093301.1 RBL00313 YP_093302.1 two-component response regulator involved in degradative enzyme and competence regulation; RBL00312 YP_093303.1 two-component sensor histidine kinase involved in degradative enzyme and competence regulation; RBL00311 YP_093304.1 RBL00310 YP_093305.1 similar to transcriptional regulator; RBL00309 YP_093306.1 RBL05032 YP_093307.1 teichoic acid linkage unit synthesis; RBL00308 YP_093308.1 biosynthesis of teichuronic acid; RBL00306 YP_093309.1 biosynthesis of teichuronic acid; RBL00305 YP_093310.1 biosynthesis of teichuronic acid; RBL00304 YP_093311.1 biosynthesis of teichuronic acid; RBL00303 YP_093312.1 putative NDP-sugar epimerase; RBL00302 YP_093313.1 biosynthesis of teichuronic acid (UDP-glucose 6-dehydrogenase); RBL00301 YP_093314.1 biosynthesis of teichuronic acid; RBL00300 YP_093315.1 biosynthesis of teichuronic acid; RBL00299 YP_093316.1 biosynthesis of teichuronic acid; RBL00298 YP_093317.1 N-acetylmuramoyl-L-alanine amidase (major autolysin); RBL00297 YP_093318.1 modifier protein of major autolysin LytC; RBL00296 YP_093319.1 RBL00294 YP_093320.1 attenuator role for lytABC and lytR expression; attenuator function for control of operon expression YP_093321.1 similar to UDP-N-acetylglucosamine 2-epimerase; RBL00292 YP_093322.1 UTP-glucose-1-phosphate uridylyltransferase; RBL00290 YP_093323.1 teichoic acid translocation (ATP-binding protein); RBL00289 YP_093324.1 teichoic acid translocation (permease); RBL00288 YP_093325.1 putative CDP-glycerolpolyglycerol phosphate glycero-phosphotransferase; RBL00287 YP_093326.1 CDP-glycerolpolyglycerol phosphate glycero-phosphotransferase; RBL05031 YP_093327.1 glycerol-3-phosphate cytidylyltransferase; RBL05030 YP_093328.1 involved in polyglycerol phosphate teichoic acid biosynthesis; RBL01584 YP_093329.1 involved in polyglycerol phosphate teichoic acid biosynthesis; RBL01583 YP_093330.1 N-acetylglucosaminidase (major autolysin); RBL01582 YP_093331.1 mannose-6-phosphate isomerase; RBL01580 YP_093332.1 putative anaerobic ribonucleoside-triphosphate reductase activating protein; RBL01579 YP_093333.1 putative anaerobic ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_093334.1 transports degraded pectin products into the bacterial cell YP_093335.1 2-keto-3-deoxygluconate-6-phosphate aldolase; RBL01576 YP_093336.1 2-keto-3-deoxygluconate kinase; RBL01575 YP_093337.1 transcriptional repressor of the pectin utilization operon; RBL01574 YP_093338.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_093339.1 2-keto-3-deoxygluconate oxidoreductase; Involved in the metabolism of 2-deoxyglucose YP_093340.1 alcohol dehydrogenase; RBL02951 YP_093341.1 similar to metabolite transport protein; RBL02953 YP_093342.1 similar to transcriptional regulator; RBL02954 YP_093343.1 RBL02955 YP_093344.1 similar to murein hydrolase; RBL02957 YP_093345.1 RBL05222 YP_093346.1 similar to capsular polyglutamate biosynthesis; RBL02958 YP_093347.1 similar to capsular polyglutamate biosynthesis; RBL02959 YP_093348.1 similar to capsular polyglutamate biosynthesis; RBL02961 YP_093349.1 transcriptional repressor of the ribose operon; RBL02962 YP_093350.1 ribokinase; RBL02963 YP_093351.1 ribose ABC transporter (membrane protein); cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_093352.1 ribose ABC transporter (ATP-binding protein); RBL02966 YP_093353.1 ribose ABC transporter (permease); RBL02968 YP_093354.1 ribose ABC transporter (ribose-binding protein); RBL02969 YP_093355.1 alpha-acetolactate decarboxylase; RBL02970 YP_093356.1 alpha-acetolactate synthase; catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_093357.1 transcriptional regulator of the alpha-acetolactate operon; RBL02973 YP_093358.1 similar to gamma-glutamyltransferase; RBL02974 YP_093359.1 similar to transcriptional regulator (Lrp/AsnC family); RBL02975 YP_093360.1 similar to chromate transport protein; RBL02976 YP_093361.1 similar to chromate transport protein; RBL02977 YP_093362.1 similar to capsular polysaccharide biosynthesis; RBL02979 YP_093363.1 similar to capsular polysaccharide biosynthesis; RBL02980 YP_093364.1 RBL05833 YP_093365.1 RBL02981 YP_093366.1 similar to SNF2 helicase; RBL02983 YP_093367.1 RBL05834 YP_093368.1 RBL02984 YP_093369.1 transcriptional repressor involved in the expression of the phosphotransferase system; RBL02985 YP_093370.1 putative fructose-6-phosphate aldolase 2; RBL02986 YP_093371.1 putative sorbitol-6-phosphate 2-dehydrogenase; catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_093372.1 putative PTS system, glucitol/sorbitol-specific IIA component; RBL02988 YP_093373.1 putative PTS system, glucitol/sorbitol-specific IIBC component; RBL02990 YP_093374.1 putative PTS system, glucitol/sorbitol-specific IIC2 component; RBL02991 YP_093375.1 putative sorbitol operon activator; RBL02993 YP_093376.1 putative transcriptional repressor; RBL02994 YP_093377.1 similar to single-strand DNA-binding protein; RBL05219 YP_093378.1 RBL05218 YP_093379.1 RBL05217 YP_093380.1 probable large conductance mechanosensitive channel protein; homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_093381.1 similar to hydroxymyristoyl-(acyl carrier protein) dehydratase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_093382.1 flagellar hook-basal body protein; RBL00485 YP_093383.1 flagellar basal-body rod protein; RBL00484 YP_093384.1 MreB-like protein; RBL05837 YP_093385.1 transcriptional regulator of sigma-E- and sigma-K-dependent genes; RBL05014 YP_093386.1 similar to transcriptional regulator (MarR family); RBL00482 YP_093387.1 similar to antibiotic resistance protein; RBL00481 YP_093388.1 similar to bacteriocin transport permease; RBL00480 YP_093389.1 inorganic pyrophosphatase; catalyzes the hydrolysis of pyrophosphate to phosphate YP_093390.1 similar to manganese-containing catalase; RBL00478 YP_093391.1 RBL00476 YP_093392.1 RBL00475 YP_093393.1 RBL00474 YP_093394.1 similar to hemolysin; RBL00473 YP_093395.1 ammonium transporter; RBL00472 YP_093396.1 nitrogen-regulated PII-like protein; RBL00471 YP_093397.1 close homolog to ClpP ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); RBL00470 YP_093398.1 putative RNA polymerase sigma factor; RBL00469 YP_093399.1 required for completion of engulfment; RBL00468 YP_093400.1 similar to phosphinothricin acetyltransferase; RBL00467 YP_093401.1 RBL00466 YP_093402.1 similar to cardiolipin synthase; RBL00465 YP_093403.1 putative multidrug efflux protein; RBL00464 YP_093404.1 RBL05838 YP_093405.1 involved in 2,3-dihydroxybenzoate biosynthesis; RBL00463 YP_093406.1 isochorismatase; RBL00460 YP_093407.1 2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E); RBL00459 YP_093408.1 isochorismate synthase; synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis YP_093409.1 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_093410.1 RBL00454 YP_093411.1 iron-uptake system (integral membrane protein); RBL00452 YP_093412.1 iron-uptake system (integral membrane protein); RBL00450 YP_093413.1 iron-uptake system (binding protein); RBL00449 YP_093414.1 similar to transcriptional regulator (AraC/XylS family); RBL00448 YP_093415.1 similar to proteins from B. subtilis; RBL00447 YP_093416.1 putative transposase; RBL05984 YP_093417.1 putative transposase; RBL06009 YP_093418.1 RBL00445 YP_093419.1 RBL00444 YP_093420.1 RBL05840 YP_093421.1 RBL05012 YP_093422.1 molybdopterin precursor; together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_093423.1 required for formate dehydrogenase activity; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_093424.1 putative oxalateformate antiporter; RBL00439 YP_093425.1 putative formate dehydrogenase alpha chain; RBL00438 YP_093426.1 similar to proteins from B. subtilis; RBL00437 YP_093427.1 similar to proteins from B. subtilis; RBL00436 YP_093428.1 required for complete dissolution of the asymmetric septum; RBL00435 YP_093429.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_093430.1 RBL00433 YP_093431.1 RBL05011 YP_093432.1 ATP synthase (subunit epsilon); part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_093433.1 ATP synthase (subunit beta); Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_093434.1 ATP synthase (subunit gamma); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_093435.1 ATP synthase (subunit alpha); produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_093436.1 ATP synthase (subunit delta); Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_093437.1 ATP synthase (subunit b); Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel YP_093438.1 ATP synthase (subunit c); Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_093439.1 ATP synthase (subunit a); Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_093440.1 ATP synthase (subunit i); RBL05841 YP_093441.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_093442.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_093443.1 RBL01585 YP_093444.1 similar to ribose 5-phosphate epimerase (pentose phosphate); catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_093445.1 similar to protein-tyrosine-phosphatase; RBL01587 YP_093446.1 RBL01589 YP_093447.1 RBL01590 YP_093448.1 RBL01591 YP_093449.1 required for processing of pro-sigma-E; RBL05844 YP_093450.1 glucose/mannoseH+ symporter; RBL01594 YP_093451.1 RBL01595 YP_093452.1 RBL01596 YP_093453.1 similar to sensory transduction pleiotropic regulatory protein; RBL01597 YP_093454.1 similar to transcriptional regulator (LacI family); RBL01598 YP_093455.1 similar to protoporphyrinogen oxidase; RBL01599 YP_093456.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_093457.1 RBL01602 YP_093458.1 remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions YP_093459.1 RBL01604 YP_093460.2 similar to malate dehydrogenase; malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_093461.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_093462.1 ribosomal protein L31; RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_093463.1 transcriptional terminator Rho; An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_093464.1 similar to glycerol-inducible protein; type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_093465.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_093466.1 similar to transaldolase (pentose phosphate); similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_093467.1 fructose-1,6-bisphosphate aldolase; catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis YP_093468.1 two-component response regulator involved in the initiation of sporulation; RBL01614 YP_093469.1 RBL01615 YP_093470.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_093471.1 RNA polymerase (delta subunit); participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_093472.1 acyl-CoA dehydrogenase; RBL01620 YP_093473.1 acyl-CoA dehydrogenase; RBL01621 YP_093474.1 3-hydroxybutyryl-CoA dehydrogenase; RBL01622 YP_093475.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_093476.1 similar to iron-sulphur-binding reductase; RBL01625 YP_093477.1 similar to cardiolipin synthetase; RBL01627 YP_093478.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_093479.1 RBL05232 YP_093480.1 agmatinase; RBL05233 YP_093481.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_093482.1 RBL05845 YP_093483.1 RBL05235 YP_093484.1 similar to penicillin-binding protein; RBL00893 YP_093485.1 RBL00894 YP_093486.1 RBL00895 YP_093487.1 similar to 4-oxalocrotonate tautomerase; RBL05236 YP_093488.1 RBL00896 YP_093489.1 RBL00897 YP_093490.1 RBL00898 YP_093491.1 RBL05237 YP_093492.1 probable regulator of transcription of sigma-F-dependent genes; RBL00899 YP_093493.1 RBL05846 YP_093494.1 RBL01282 YP_093495.1 putative hydroxybenzoate hydroxylase; catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_093496.1 putative benzoate transport protein; RBL01284 YP_093497.1 putative aromatic compounds specific dioxygenase; RBL01285 YP_093498.1 putative 4-oxalocrotonate tautomerase; 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_093499.1 putative decarboxylase/dehydratase; RBL01286 YP_093500.1 close homolog to DhaS aldehyde dehydrogenase; RBL01287 YP_093501.1 putative transcriptional regulator; RBL01289 YP_093502.1 RBL01290 YP_093503.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_093504.1 RBL04531 YP_093505.1 similar to proteins from B. subtilis; RBL05241 YP_093506.1 RBL05242 YP_093507.1 similar to Na+-transporting ATP synthase; RBL02833 YP_093508.1 RBL02834 YP_093509.1 similar to ABC transporter (ATP-binding protein); RBL02835 YP_093510.1 putative multidrug ABC transporter, permease protein; RBL02836 YP_093511.1 similar to ABC transporter (ATP-binding protein); RBL02837 YP_093512.1 similar to two-component sensor histidine kinase [YxjL]; RBL02838 YP_093513.1 similar to two-component response regulator [YfiJ]; RBL02839 YP_093514.1 RBL02840 YP_093515.1 RBL02841 YP_093516.1 RBL02842 YP_093517.1 similar to aldehyde dehydrogenase; RBL02843 YP_093518.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_093519.1 RBL02845 YP_093520.1 possible phosphomethylpyrimidine kinase; catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine YP_093521.1 RBL02847 YP_093522.1 sucrase-6-phosphate hydrolase; RBL02848 YP_093523.1 PTS sucrose-specific enzyme IIBC component; RBL02849 YP_093524.1 transcriptional antiterminator involved in positive regulation of sacA and sacP; RBL02850 YP_093525.1 minor extracellular serine protease; RBL02852 YP_093526.1 RBL02853 YP_093527.1 similar to monooxygenase; RBL02854 YP_093528.1 FMN-containing NADPH-linked nitro/flavin reductase; RBL02855 YP_093529.1 putative N-acyl-L-amino acid amidohydrolase; RBL02856 YP_093530.1 control of cell shape and elongation; RBL02857 YP_093531.1 close homolog to RodA control of cell shape and elongation; RBL02858 YP_093532.1 RBL01749 YP_093533.1 RBL05244 YP_093534.1 RBL05245 YP_093535.1 RBL01750 YP_093536.1 RBL01751 YP_093537.1 putative ATP-binding protein of ABC transporter; RBL01752 YP_093538.1 putative ATP-binding protein of ABC transporter; RBL01753 YP_093539.1 putative asparagine synthetase; RBL01754 YP_093540.1 RBL01755 YP_093541.1 RBL05246 YP_093542.1 putative response regulator; RBL01756 YP_093543.1 cytochrome aa3 quinol oxidase (subunit IV); RBL05247 YP_093544.1 cytochrome aa3 quinol oxidase (subunit III); RBL05248 YP_093545.1 cytochrome aa3 quinol oxidase (subunit I); RBL01761 YP_093546.1 cytochrome aa3 quinol oxidase (subunit II); RBL01762 YP_093547.1 UDP-glucose 4-epimerase; RBL01763 YP_093548.1 RBL05848 YP_093549.1 RBL05250 YP_093550.1 RBL01764 YP_093551.1 RBL01765 YP_093552.1 similar to Na+-dependent symport; RBL01767 YP_093553.1 xylulose kinase; RBL01768 YP_093554.1 catalyzes the interconversion of D-xylose to D-xylulose YP_093555.1 transcriptional repressor of the xylose operon; RBL01770 YP_093556.1 RBL05849 YP_093557.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_093558.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_093559.1 similar to transcriptional regulator (LysR family); RBL01773 YP_093560.1 similar to transcriptional regulator (LysR family); RBL01774 YP_093561.1 putative two-component sensor histidine kinase; RBL05251 YP_093562.1 RBL01775 YP_093563.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB YP_093564.1 RBL01778 YP_093565.1 close homolog to OpuE proline transporter; RBL05850 YP_093566.1 RBL05252 YP_093567.1 RBL01020 YP_093568.1 similar to phosphoglycerate dehydrogenase; RBL01021 YP_093569.1 putative phosphoglycerate dehydrogenase; RBL01022 YP_093570.1 general stress protein; RBL01023 YP_093571.1 similar to two-component sensor histidine kinase [YdfI]; RBL01024 YP_093572.1 similar to two-component response regulator [YdfH]; RBL01025 YP_093573.1 similar to antibiotic transport-associated protein; RBL01026 YP_093574.1 RBL01027 YP_093575.1 putative galactonate transporter; RBL01028 YP_093576.1 putative galactonate dehydratase protein; RBL01029 YP_093577.1 putative 2-keto-3-deoxygluconate-6-phosphate aldolase; RBL01030 YP_093578.1 putative 2-keto-3-deoxygluconate kinase; RBL01031 YP_093579.1 putative transcriptional regulator; RBL01033 YP_093580.1 similar to aminopeptidase; RBL01034 YP_093581.1 similar to transporter; RBL01035 YP_093582.1 RBL05851 YP_093583.1 RBL05253 YP_093584.1 similar to GTP-pyrophosphokinase; RBL01037 YP_093585.1 D-alanyl-D-alanine carrier protein ligase; RBL05852 YP_093586.1 D-alanine-D-alanyl carrier protein ligase; transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_093587.1 D-alanine transfer from Dcp to undecaprenol-phosphate; RBL01041 YP_093588.1 D-alanine carrier protein; D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_093589.1 D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain; RBL05256 YP_093590.1 similar to branched-chain amino acid aminotransferase; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_093591.1 similar to macrolide-efflux protein; RBL01045 YP_093592.1 6-phospho-beta-glucosidase; RBL01047 YP_093593.1 PTS lichenan-specific enzyme IIA component; RBL05257 YP_093594.1 PTS lichenan-specific enzyme IIC component; RBL01049 YP_093595.1 PTS lichenan-specific enzyme IIB component; RBL01050 YP_093596.1 transcriptional activator of the lichenan operon; RBL01052 YP_093597.1 RBL05854 YP_093598.1 similar to DNA-3-methyladenine glycosidase; responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_093599.1 putative transcriptional regulator; RBL01054 YP_093600.1 citrate synthase III; forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration YP_093601.1 function; functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_093602.1 similar to phosphoenolpyruvate mutase; RBL01057 YP_093603.1 putative chromate transport protein; RBL01058 YP_093604.1 RBL01059 YP_093605.1 similar to ABC transporter (ATP-binding protein); RBL01060 YP_093606.1 putative pectin acetylesterase; RBL05665 YP_093607.1 RBL05855 YP_093608.1 similar to proteins from B. subtilis; RBL05856 YP_093609.1 putative bicyclomycin resistance protein; RBL02647 YP_093610.1 RBL02648 YP_093611.1 similar to ABC transporter (ATP-binding protein); RBL02649 YP_093612.1 RBL05213 YP_093613.1 RBL05857 YP_093614.1 RBL02650 YP_093615.1 RNA polymerase ECF-type sigma factor; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_093616.1 similar to multidrug-efflux transporter; RBL02652 YP_093617.1 major catalase in spores; RBL02653 YP_093618.1 RBL05858 YP_093619.1 vegetative catalase 1; RBL02656 YP_093620.1 putative transcriptional repressor of the peroxide regulon; RBL05212 YP_093621.1 close homolog to HemH ferrochelatase; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_093622.1 RBL02660 YP_093623.1 putative ABC transporter ATP-binding protein; RBL02661 YP_093624.1 RBL02663 YP_093625.1 RBL02665 YP_093626.1 RBL02666 YP_093627.1 RBL05211 YP_093628.1 putative transcriptional regulator; RBL05210 YP_093629.1 RBL05209 YP_093630.1 RBL02667 YP_093631.1 putative ABC-transporter, membrane protein; RBL02669 YP_093632.1 putative bacteriocin formation protein; RBL02670 YP_093633.1 putative lantibiotic mersacidin precursor; RBL05208 YP_093634.1 putative bacteriocin formation protein; RBL02671 YP_093635.1 putative pectate lyase; RBL02672 YP_093636.1 RBL02673 YP_093637.1 ABC transporter required for expression of cytochrome bd (ATP-binding protein); RBL02674 YP_093638.1 ABC transporter required for expression of cytochrome bd (ATP-binding protein); RBL02675 YP_093639.1 cytochrome bd ubiquinol oxidase (subunit II); RBL02676 YP_093640.1 cytochrome bd ubiquinol oxidase (subunit I); RBL02677 YP_093641.1 similar to nitrite transporter; RBL02678 YP_093642.1 RBL02679 YP_093643.1 probable malolactic enzyme; RBL02680 YP_093644.1 malate-H+/Na+-lactate antiporter; RBL05859 YP_093645.1 close homolog to AnsB L-aspartase; catalyzes the formation of fumarate from aspartate YP_093646.1 L-asparaginase; RBL05205 YP_093647.1 transcriptional repressor of the ansAB operon; RBL05204 YP_093648.1 RBL03857 YP_093649.1 putative two-component response regulator, fragment 2; RBL03858 YP_093650.1 putative two-component response regulator, fragment 1; RBL05203 YP_093651.1 similar to two-component sensor histidine kinase [YxdJ]; RBL03859 YP_093652.1 similar to ABC transporter (ATP-binding protein); RBL03860 YP_093653.1 similar to ABC transporter (permease); RBL03862 YP_093654.1 RBL03863 YP_093655.1 RBL05200 YP_093656.1 RBL05199 YP_093657.1 RBL03865 YP_093658.1 putative transcriptional regulator (GntR family); RBL05860 YP_093659.1 putative transcriptional regulator (GntR family); RBL03866 YP_093660.1 RBL03867 YP_093661.1 similar to metabolite-sodium symport; RBL03868 YP_093662.1 putative beta-glucosidase; RBL03869 YP_093663.1 RBL05196 YP_093664.1 RBL05195 YP_093665.1 similar to anion-binding protein; RBL02011 YP_093666.1 similar to proteins from B. subtilis; RBL02012 YP_093667.1 RBL02013 YP_093668.1 close homolog to AhrC transcriptional regulator of arginine metabolism expression; RBL02014 YP_093669.1 (ADI) (Arginine dihydrolase) (AD); catalyzes the degradation of arginine to citruline and ammonia YP_093670.1 OTCase; catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_093671.1 putative sugar permease; RBL02018 YP_093672.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_093673.1 putative transcriptional regulator of anaerobic genes; RBL02021 YP_093674.1 putative ABC transporter (ATP-binding protein); RBL02022 YP_093675.1 putative PTS enzyme IIC component; RBL02023 YP_093676.1 RBL02024 YP_093677.1 putative RNA polymerase ECF-type sigma factor; RBL02025 YP_093678.1 putative anaerobic ribonucleoside-triphosphate reductase activating protein; RBL02026 YP_093679.1 RBL02027 YP_093680.1 RBL05861 YP_093681.1 RBL02028 YP_093682.1 putative cell-division protein / general stress protein (class III heat-shock); RBL02029 YP_093683.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_093684.1 putative sucrose-6-phosphate hydrolase; RBL02033 YP_093685.1 similar to sugar permease; lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_093686.1 putative sugar ABC transporter, permease; RBL02035 YP_093687.1 similar to sugar permease; RBL02036 YP_093688.1 putative sugar ABC transporter sugar binding protein; RBL02037 YP_093689.1 putative repressor; RBL02038 YP_093690.1 RBL02039 YP_093691.1 RBL02040 YP_093692.1 RBL05194 YP_093693.1 similar to proteins from B. subtilis; RBL02041 YP_093694.1 similar to proteins from B. subtilis; RBL02045 YP_093695.1 similar to dolichol phosphate mannose synthase; RBL02046 YP_093696.1 putative NDP-sugar epimerase; RBL02047 YP_093697.1 RBL02048 YP_093698.1 RBL02049 YP_093699.1 RBL02050 YP_093700.1 RBL04837 YP_093701.1 similar to pyrimidine nucleoside transport; RBL02051 YP_093702.1 catalase 2; RBL02053 YP_093703.1 catalase 2; RBL02055 YP_093704.1 RBL02056 YP_093705.1 putative beta-glucosidase; RBL02057 YP_093706.1 close homolog to BglP PTS enzyme IIBCA component; RBL02058 YP_093707.1 transcriptional antiterminator required for substrate-dependent induction and catabolite repression of bglPH; RBL02059 YP_093708.1 RBL02060 YP_093709.1 similar to cation ABC transporter (ATP-binding protein); RBL02061 YP_093710.1 RBL02062 YP_093711.1 putative transcriptional regulator; RBL02063 YP_093712.1 RBL05193 YP_093713.1 putative isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_093714.1 putative malate synthase; Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_093715.1 similar to proteins from B. subtilis; RBL02068 YP_093716.1 similar to ABC transporter (permease); RBL02069 YP_093717.1 similar to ABC transporter (ATP-binding protein); RBL02070 YP_093718.1 similar to two-component sensor histidine kinase [YtsA]; RBL02071 YP_093719.1 similar to two-component response regulator [YtsB]; RBL02072 YP_093720.1 beta-glucosidase; RBL02073 YP_093721.1 PTS beta-glucoside-specific enzyme IIBCA component; RBL02074 YP_093722.1 RBL02075 YP_093723.1 similar to penicillin amidase; RBL02076 YP_093724.1 RBL02077 YP_093725.1 RBL02078 YP_093726.1 similar to arabinan endo-1,5-alpha-L-arabinosidase; RBL02079 YP_093727.1 ATP-dependent RNA helicase; RBL02080 YP_093728.1 RBL02081 YP_093729.1 RBL05192 YP_093730.1 putative transposase; RBL05191 YP_093731.1 RBL04758 YP_093732.1 RBL03696 YP_093733.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_093734.1 pyrimidine-nucleoside transport protein; RBL03693 YP_093735.1 deoxyribose-phosphate aldolase; RBL03692 YP_093736.1 transcriptional repressor of the dra-nupC-pdp operon; RBL03691 YP_093737.1 RBL03690 YP_093738.1 RBL03689 YP_093739.1 RBL03688 YP_093740.1 RBL03687 YP_093741.1 similar to cellulose synthase; RBL03684 YP_093742.1 RBL03683 YP_093743.1 similar to aspartate aminotransferase; transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_093744.1 RBL03680 YP_093745.1 RBL03679 YP_093746.1 RBL03678 YP_093747.1 putative transporter; RBL03677 YP_093748.1 fructose-1,6-bisphosphate aldolase; RBL03675 YP_093749.1 myo-inositol catabolism; RBL03674 YP_093750.1 myo-inositol catabolism; RBL03673 YP_093751.1 myo-inositol 2-dehydrogenase; RBL03672 YP_093752.1 inositol transport protein; RBL03671 YP_093753.1 myo-inositol catabolism; RBL03670 YP_093754.1 myo-inositol catabolism; RBL03669 YP_093755.1 myo-inositol catabolism; RBL03668 YP_093756.1 myo-inositol catabolism; RBL03667 YP_093757.1 putative methylmalonate-semialdehyde dehydrogenase [acylating]; RBL03665 YP_093758.1 transcriptional repressor of the myo-inositol catabolism operon; RBL03663 YP_093759.1 myo-inositol catabolism; RBL03661 YP_093760.1 glycerophosphoryl diester phosphodiesterase; RBL03658 YP_093761.1 glycerol-3-phosphate permease; RBL03656 YP_093762.1 class III heat-shock protein (molecular chaperone) YP_093763.1 putative ABC transporter, ATP-binding protein; RBL03653 YP_093764.1 RBL03652 YP_093765.1 putative glycerol 1-phosphate dehydrogenase; RBL03651 YP_093766.1 RBL03650 YP_093767.1 RBL03649 YP_093768.1 similar to ABC transporter (binding protein); RBL03648 YP_093769.1 RBL03647 YP_093770.1 RBL03646 YP_093771.1 putative ferrous iron transport protein B; RBL03645 YP_093772.1 RBL04757 YP_093773.1 similar to surface adhesion; RBL03644 YP_093774.1 RBL03643 YP_093775.1 RBL03642 YP_093776.1 RBL03641 YP_093777.1 similar to two-component response regulator [YxdK]; RBL03640 YP_093778.1 RBL05190 YP_093779.1 similar to methyl-accepting chemotaxis protein; RBL03637 YP_093780.1 putative amino acid symporter; RBL03635 YP_093781.1 close homolog to Ald L-alanine dehydrogenase; RBL03634 YP_093782.1 similar to arabinogalactan endo-1,4-beta-galactosidase; RBL03633 YP_093783.1 beta-galactosidase; RBL03632 YP_093784.1 similar to maltodextrin transport system permease; RBL03631 YP_093785.1 similar to maltodextrin transport system permease; RBL03630 YP_093786.1 similar to maltose/maltodextrin-binding protein; RBL03629 YP_093787.1 transcriptional repressor of the beta-galactosidase gene; RBL03628 YP_093788.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_093789.1 close homolog to GalE UDP-glucose 4-epimerase; RBL03626 YP_093790.1 galactose-1-phosphate uridyltransferase; catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism YP_093791.1 putative transcriptional repressor of the xylose operon; RBL03623 YP_093792.1 transcriptional repressor of the gluconate operon; RBL03622 YP_093793.1 Gluconokinase (Gluconate kinase); RBL03621 YP_093794.1 gluconate permease; RBL03619 YP_093795.1 6-phosphogluconate dehydrogenase, decarboxylating; catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_093796.1 putative alcohol dehydrogenase/acetaldehyde dehydrogenase; RBL03615 YP_093797.1 alkyl hydroperoxide reductase (small subunit); RBL03613 YP_093798.1 alkyl hydroperoxide reductase (large subunit) / NADH dehydrogenase; RBL03612 YP_093799.1 RBL03608 YP_093800.1 RBL03607 YP_093801.1 RBL04756 YP_093802.1 RBL03606 YP_093803.1 RBL04755 YP_093804.1 similar to ABC transporter (ATP-binding protein); RBL03605 YP_093805.1 similar to ABC transporter transmembrane subunit; RBL05862 YP_093806.1 similar to ABC transporter transmembrane subunit; RBL03603 YP_093807.1 RBL04754 YP_093808.1 similar to two-component sensor histidine kinase [YvfU]; RBL03602 YP_093809.1 similar to two-component response regulator [YvfT]; RBL03600 YP_093810.1 RBL03599 YP_093811.1 RBL04753 YP_093812.1 putative ABC transporter ATP-binding protein; RBL03598 YP_093813.1 RBL04752 YP_093814.1 RBL05189 YP_093815.1 RBL04751 YP_093816.1 RBL05864 YP_093817.1 RBL05865 YP_093818.1 RBL05866 YP_093819.1 putative metal-dependent hydrolase; RBL05867 YP_093820.1 putative type I restriction enzyme (restriction chain); RBL05868 YP_093821.1 putative type I restriction enzyme hsdS subunit; RBL03245 YP_093822.1 putative DNA-binding protein; RBL03246 YP_093823.1 putative type I site-specific deoxyribonuclease; RBL03247 YP_093824.1 RBL04500 YP_093825.1 RBL04338 YP_093826.1 RBL05507 YP_093827.1 putative site-specific recombinase; RBL04339 YP_093828.1 site-specific DNA recombinase required for creating the sigK gene (excision of the skin element); RBL05508 YP_093829.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_093830.1 RBL05510 YP_093831.1 RBL03826 YP_093832.1 RBL03827 YP_093833.1 RBL03828 YP_093834.1 RBL03830 YP_093835.1 similar to serine protease Do; RBL03832 YP_093836.1 RBL03833 YP_093837.1 RBL03835 YP_093838.1 RBL03836 YP_093839.1 similar to two-component sensor histidine kinase [YycF]; RBL03837 YP_093840.1 similar to two-component response regulator [YycG]; RBL03838 YP_093841.1 RBL03839 YP_093842.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_093843.1 putative holin; RBL05511 YP_093844.1 unwinds double stranded DNA YP_093845.1 RBL05869 YP_093846.1 RBL05870 YP_093847.1 RBL05514 YP_093848.1 similar to ABC transporter (permease); RBL05871 YP_093849.1 N-acetylglucosamine-6-phosphate deacetylase; RBL01563 YP_093850.1 putative N-acetylglucosamine-6-phosphate isomerase; RBL01564 YP_093851.1 similar to transcriptional regulator (GntR family); RBL01565 YP_093852.1 putative 3-oxoacyl- acyl-carrier protein reductase; catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_093853.1 putative PTS N-acetylglucosamine-specific enzyme IICB component; RBL01568 YP_093854.1 ribosomal protein L9; in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_093855.1 RBL05872 YP_093856.1 RBL01573 YP_093857.1 spore coat protein; RBL05873 YP_093858.1 spore coat protein; RBL05517 YP_093859.1 RBL05518 YP_093860.1 similar to sulfate permease; RBL05519 YP_093861.1 similar to ABC transporter (permease); RBL05520 YP_093862.1 ribosomal protein S18; binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_093863.1 single-strand DNA-binding protein; RBL05112 YP_093864.1 ribosomal protein S6 (BS9); binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_093865.1 similar to GTP-binding protein; translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_093866.1 RBL05525 YP_093867.1 similar to proteins from B. subtilis; RBL00271 YP_093868.1 RBL00270 YP_093869.1 chromosome positioning near the pole and transport through the polar septum / antagonist of Soj-dependent inhibition of sporulation initiation; RBL00268 YP_093870.1 centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation; RBL00267 YP_093871.1 RBL00266 YP_093872.1 putative RNA polymerase sigma factor; RBL00265 YP_093873.1 similar to DNA-binding protein Spo0J-like; RBL00264 YP_093874.1 glucose-inhibited division protein; glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_093875.1 glucose-inhibited division protein; GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_093876.1 thiophen and furan oxidation; in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_093877.1 SpoIIIJ-associated protein; RBL00259 YP_093878.1 essential for sigma-G activity at stage III; involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation YP_093879.1 protein component of ribonuclease P (RNase P); protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_093880.1 ribosomal protein L34; in Escherichia coli transcription of this gene is enhanced by polyamines