-- dump date 20140618_223457 -- class Genbank::CDS -- table cds_note -- id note NP_387882.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_387883.1 binds the polymerase to DNA and acts as a sliding clamp NP_387884.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_387885.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_387886.2 Evidence 4: Homologs of previously reported genes of unknown function NP_387887.1 negatively supercoils closed circular double-stranded DNA NP_387888.1 negatively supercoils closed circular double-stranded DNA NP_387889.1 Evidence 4: Homologs of previously reported genes of unknown function NP_387890.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_387891.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8370539, 9864321; Product type e: enzyme NP_387892.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_387893.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate NP_387894.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_387895.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735, 6251049; Product type e: enzyme NP_387896.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735; Product type e: enzyme NP_387897.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 11737650, 12177332, 10419957; Product type e: enzyme NP_387898.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2521622; Product type pe : enzyme NP_387899.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16700551; Product type e: enzyme NP_387900.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_387901.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16740939; Product type f: factor NP_387902.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_387903.1 Evidence 4: Homologs of previously reported genes of unknown function NP_387904.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15087499; Product type r: regulator NP_387905.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 8759874; Product type cp: cell process NP_387906.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_387907.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12533473 NP_387908.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9723923; Product type pe : enzyme NP_387909.2 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_387910.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913081 NP_387911.1 Evidence 4: Homologs of previously reported genes of unknown function NP_387912.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_387913.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12270811 NP_387914.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA NP_387915.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_387916.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11483577; Product type pe : enzyme NP_387917.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme NP_387918.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 16223496, 16702211, 10754235, 10809710, 11101881, 11101897; Product type r: regulator NP_387919.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_387920.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10747959, 16014871; Product type e: enzyme NP_387921.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001, 19047346; Product type pe: enzyme NP_387922.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11233981, 11976317, 12794188, 16077031; Product type e: enzyme NP_387923.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_387924.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 11040425, 16751597, 19060142; Product type cp: cell process NP_387925.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12761295 NP_387926.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11092849, 7959056, 8982008; Product type cp: cell process NP_387927.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis NP_387928.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12837783, 12837784, 15629952, 16163456; Product type r: regulator NP_387929.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12515541, 14729707, 10557275, 10919400, 10368157; Product type pe: enzyme NP_387930.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus NP_387931.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_387932.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_387933.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_387934.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_387935.1 Evidence 4: Homologs of previously reported genes of unknown function NP_387936.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 16950921, 8594198, 9535092; Product type f: factor NP_387937.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15063493, 15939023, 16159768, 18996130, 8755877; Product type r: regulator NP_387938.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_387939.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11178267; Product type pe : enzyme NP_387940.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10675343, 10675344; Product type pf: factor NP_387941.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15231775, 10869437; Product type f: factor NP_387942.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15849754, 16850406, 10869437; Product type f: factor NP_387943.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 11994149, 12682299, 16936019; Product type f: factor NP_387944.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066026, 16014871, 9862121; Product type pe: enzyme NP_387945.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10747015, 12180929, 15126482, 15866939, 15978076; Product type e: enzyme NP_387946.1 Evidence 4: Homologs of previously reported genes of unknown function NP_387947.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_387948.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14527414, 16039592, 17005971; Product type e: enzyme NP_387949.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 3110131, 6408059; Product type e: enzyme NP_387950.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10851010, 10913836, 12533473, 9076729, 9084181, 9287010, 9352926; Product type e: enzyme NP_387951.2 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP NP_387952.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers NP_387953.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182, 15856219; Product type pf: factor NP_387954.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 16267287, 16513748; Product type e: enzyme NP_387955.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16605270, 17114263, 2123867, 9084182; Product type e: enzyme NP_387956.1 amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis NP_387957.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate NP_387958.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11007651, 2123867; Product type e: enzyme NP_387959.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16188473, 17176045, 17388809; Product type e : enzyme NP_387960.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17029412; Product type e: enzyme NP_387961.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_387962.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710, 15698474; Product type e: enzyme NP_387963.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_387964.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069659, 12618461, 16163393, 9852015; Product type r: regulator NP_387965.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16163393; Product type f: factor NP_387966.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16163393, 17380125; Product type e: enzyme NP_387967.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354604, 15529410, 16525504; Product type f: factor NP_387968.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_387969.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair NP_387970.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_387971.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_387972.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_387973.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_387974.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751, 10737181, 7510287; Product type e: enzyme NP_387975.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_387976.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871; Product type e: enzyme NP_387977.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11698387, 16014871; Product type e: enzyme NP_387978.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114934; Product type pe : enzyme NP_387979.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates NP_387980.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif NP_387981.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_387982.1 Modulates Rho-dependent transcription termination NP_387983.2 binds directly to 23S ribosomal RNA NP_387984.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_387985.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_387986.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_387987.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17010380; Product type e: enzyme NP_387988.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_387989.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_387990.1 in Bacillus subtilis this non-essential protein associates with the ribosome NP_387991.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_387992.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_387993.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_387994.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_387995.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_387996.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_387997.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_387998.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_387999.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_388000.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_388001.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_388002.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_388003.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_388004.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_388005.1 one of the stabilizing components for the large ribosomal subunit NP_388006.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_388007.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_388008.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_388009.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_388010.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif NP_388011.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_388012.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_388013.2 binds 5S rRNA along with protein L5 and L25 NP_388014.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_388015.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_388016.1 late assembly protein NP_388017.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_388018.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_388019.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_003097669.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17157877; Product type pf : factor NP_388020.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_388021.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_388022.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_388023.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_388024.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_388025.1 is a component of the macrolide binding site in the peptidyl transferase center NP_388026.2 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene NP_388027.1 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene NP_388028.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388029.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_388030.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_388031.1 forms a direct contact with the tRNA during translation NP_388032.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388033.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227, 16267290; Product type pe: enzyme NP_388034.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 16267290; Product type e: enzyme NP_388035.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11790741, 15126467; Product type r: regulator NP_388036.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17122337, 10618233, 10376819; Product type f: factor NP_388037.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8576055; Product type r: regulator NP_388038.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 15547282; Product type ph: phenotype NP_388039.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type m: membrane component NP_388040.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388041.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 2974033; Product type pe: enzyme NP_388042.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter NP_388043.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter NP_388044.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8388528; Product type lp: lipoprotein NP_388045.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388046.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388047.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8063094; Product type pe : enzyme NP_388048.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16452451; Product type pe : enzyme NP_388049.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 10627040; Product type pt: transporter NP_388050.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388051.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway NP_388052.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388053.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388054.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial NP_388055.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127; Product type r: regulator NP_388056.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388057.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16236721 NP_388058.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_388059.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_388061.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7565865, 8376346; Product type e: enzyme NP_388062.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme NP_388063.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme NP_388064.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_388065.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388067.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388068.1 Evidence 5: No homology to any previously reported sequences NP_388069.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097670.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388070.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15812018, 15849754, 16850406; Product type pt: transporter NP_388071.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388072.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type f: factor NP_388073.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 18307109; Product type f: factor YP_003097671.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter NP_388077.1 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter NP_388078.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter NP_388079.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype NP_388080.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype NP_388081.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388082.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator NP_388083.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor YP_003097672.1 Evidence 5: No homology to any previously reported sequences NP_388085.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388086.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16794953; Product type h : extrachromosomal origin NP_388087.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type h : extrachromosomal origin NP_388088.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388089.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9016963; Product type cp: cell process NP_388090.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388091.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14742199; Product type e: enzyme NP_388092.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10529095; Product type e: enzyme NP_388093.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388094.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388095.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081; Product type e: enzyme NP_388096.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406, 8012593; Product type t: transporter NP_388097.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388098.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388099.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388100.2 Evidence 5: No homology to any previously reported sequences NP_388101.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388102.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388103.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388104.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388105.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis NP_388106.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15375126; Product type e: enzyme NP_388107.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388108.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11389736; Product type e: enzyme NP_388109.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14762009, 15743965, 15849754, 16850406; Product type e: enzyme NP_388110.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 14762009, 15849754, 16850406; Product type pe: enzyme NP_388111.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine NP_388112.1 Evidence 5: No homology to any previously reported sequences NP_388113.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388114.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388115.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme NP_388116.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7751298; Product type t: transporter NP_388117.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10627040, 15849754, 16850406; Product type t : transporter NP_388118.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme NP_388119.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388120.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008 NP_388121.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_388122.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 7704263; Product type pt: transporter NP_388123.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines NP_388124.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 15995196, 16850406; Product type t: transporter NP_388125.1 catalyzes the formation of glutamate from glutamine NP_388126.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 11717295, 15995196; Product type rc : receptor NP_388127.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15995196; Product type r: regulator NP_388128.2 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate NP_388129.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12044674, 17202142; Product type e: enzyme NP_388130.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674, 15849754, 16850406; Product type t: transporter NP_388131.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type e: enzyme NP_388132.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type r: regulator NP_388133.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 9772162; Product type e: enzyme NP_388134.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12044674; Product type pe : enzyme NP_388135.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10706627, 11557884, 12855807, 15099736, 15213402, 15743934, 16306262; Product type r: regulator NP_388136.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10706627, 15063849, 15849754, 16850406, 16879415, 17114263; Product type pt : transporter NP_388137.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator NP_388138.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_388139.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040; Product type pt : transporter NP_388140.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388141.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388142.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11466292, 11807087, 12177332, 16936016, 9515903; Product type e: enzyme NP_388143.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097673.1 Evidence 6: Doubtful CDS NP_388144.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719524, 12867413, 16698798; Product type e: enzyme NP_388145.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12867413, 15554971, 16678787, 19049517; Product type t: transporter NP_388146.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16698798, 19049517; Product type t: transporter NP_388147.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline NP_388148.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388149.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15317768, 15849754, 16850406; Product type t: transporter NP_388150.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12718394, 15317768, 17483215; Product type r: regulator NP_388151.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 17686772; Product type e: enzyme NP_388152.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 18053819, 11029590, 8396026; Product type e: enzyme NP_388153.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388154.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388155.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type rc: receptor NP_388156.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type r: regulator NP_388157.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 17322186; Product type t: transporter NP_388158.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 17322186; Product type t: transporter NP_388159.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17322186; Product type pe : enzyme NP_388160.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388161.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388162.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388163.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17588176; Product type e: enzyme NP_388164.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme NP_388165.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme NP_388166.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544224; Product type pe : enzyme NP_388167.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12426338, 14730579, 9379902; Product type lp : lipoprotein NP_388168.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9379902, 9811636; Product type t : transporter NP_388169.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 9379902, 9811636; Product type t: transporter NP_388170.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16428414; Product type pe : enzyme NP_388171.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388172.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388173.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388174.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388175.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388176.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388177.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388178.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388179.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388180.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type t: transporter NP_388181.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16225868, 16645306, 16850406, 8752321; Product type t : transporter NP_388182.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type lp: lipoprotein NP_388183.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8768514; Product type e : enzyme NP_388184.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388185.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388186.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3117969, 9353930; Product type e: enzyme NP_388187.2 Converts (S)-lactate and NAD(+) to pyruvate and NADH NP_388188.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 15849754, 16428414, 16850406; Product type t: transporter NP_388189.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15489457, 15849754, 16850406, 9023234; Product type t: transporter NP_388190.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388191.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388192.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388193.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388194.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16433904; Product type pe : enzyme NP_388195.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_388196.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15131133, 1624425, 7766032; Product type f: factor NP_388197.2 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_388198.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388199.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pr : regulator NP_388200.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12842474; Product type e: enzyme NP_388201.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388202.1 Evidence 1b: Function experimentally demonstrated in the studied species; PubMedId: 17536821, 2118500; Product type e: enzyme NP_388203.2 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate NP_388204.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14976255, 15849754, 16850406; Product type pt: transporter NP_388205.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388206.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388207.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388208.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388209.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16672620; Product type pe : enzyme NP_388210.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme NP_388211.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme NP_388212.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme NP_388213.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme NP_388214.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10940050, 10972836, 15028686, 7836289, 9765565; Product type e: enzyme NP_388215.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7868621; Product type t: transporter NP_388216.2 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis NP_388217.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338; Product type pt : transporter YP_003097674.1 Evidence 5: No homology to any previously reported sequences NP_388218.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338, 18344368, 2013568, 9811636; Product type pt: transporter NP_388219.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388220.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388221.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388222.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388223.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18069788; Product type e: enzyme NP_388224.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663; Product type r: regulator NP_388225.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663, 2841296, 7746143; Product type e: enzyme NP_388226.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187186, 7704255, 7921238; Product type rc : receptor NP_388227.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme NP_388228.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme NP_388229.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15978081; Product type r: regulator NP_388230.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 8288534, 8441623; Product type e: enzyme NP_388231.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme NP_388232.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10361283, 16554821, 8752331, 9696775; Product type r: regulator NP_388233.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme NP_388234.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16166527, 16553878, 17227471; Product type e: enzyme NP_388235.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388236.1 Evidence 5: No homology to any previously reported sequences NP_388237.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388238.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388240.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 17827323; Product type m : membrane component NP_388241.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter NP_388242.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter NP_388243.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter NP_388244.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388245.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10919793; Product type pe : enzyme NP_388246.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11029449, 18388975; Product type pe: enzyme YP_003097675.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15979273, 18388975; Product type e: enzyme NP_388247.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15979273; Product type pe : enzyme NP_388248.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388249.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717292, 15849754, 16850406, 8458848; Product type t: transporter NP_388250.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388251.1 Evidence 5: No homology to any previously reported sequences NP_388252.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process NP_388253.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process NP_388254.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 15849754, 16707705, 16740944, 16850406; Product type cp: cell process NP_388255.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388256.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388257.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type r: regulator NP_388258.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type rc: receptor NP_388259.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917; Product type e: enzyme NP_388260.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917, 16816200; Product type r: regulator YP_003097677.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388261.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive NP_388262.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter NP_388263.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter NP_388264.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter NP_388265.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter NP_388266.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388267.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388268.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16229462, 9836433; Product type e: enzyme NP_388269.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388270.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388271.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311; Product type r: regulator NP_388272.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate NP_388273.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 15590624, 9723923; Product type e : enzyme NP_388274.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438764, 15849754, 16850406; Product type t : transporter NP_388275.1 Converts glucose to D-glucono-1,5 lactone NP_388276.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388277.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter NP_388278.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pr : regulator NP_388279.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 18307109; Product type pe: enzyme NP_388280.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter YP_003097678.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter NP_388281.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme NP_388282.3 catalyzes the formation of oxaloglycolate from tartrate; also catalyzes the formation of pyruvate from malate and glycerate from tartrate NP_388283.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14568161, 9325333; Product type e: enzyme NP_388284.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388285.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16291680; Product type pe: enzyme YP_003097679.1 Evidence 5: No homology to any previously reported sequences NP_388286.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388287.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme NP_388288.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9334321; Product type pt: transporter NP_388289.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321 NP_388290.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pf : factor YP_054571.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme NP_388291.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9334321; Product type r: regulator NP_388292.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17220230, 9334321; Product type e: enzyme NP_388293.1 Evidence 5: No homology to any previously reported sequences NP_388294.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388295.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8830698; Product type lp: lipoprotein NP_388296.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388297.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type r: regulator NP_388298.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388299.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388300.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme NP_388301.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166 NP_388302.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15468321; Product type pe : enzyme NP_388303.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor NP_388304.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388305.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388306.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10606655, 10913073, 12458218, 16407330, 16528101, 9341680; Product type r : regulator NP_388307.1 decatenates replicating daughter chromosomes NP_388308.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388309.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388310.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388311.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388312.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388313.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter NP_388314.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513759; Product type pe : enzyme NP_388315.1 catalyzes the formation of acetyl phosphate from pyruvate YP_003097680.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388317.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029030, 12950915, 14580210, 15849754, 16850406; Product type t : transporter NP_388318.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388319.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388320.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388321.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651322, 9669336; Product type f: factor NP_388322.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme NP_388323.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388324.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15231799; Product type pe : enzyme NP_388325.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10708364, 11566984, 1809844; Product type f : factor NP_388326.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type rc: receptor NP_388327.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type r: regulator NP_388328.1 involved in the transport of C4-dicarboxylates across the membrane NP_388329.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388330.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388331.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 15849754, 16850406; Product type pt: transporter NP_388332.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388333.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748; Product type pe: enzyme NP_388334.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229, 16428414 NP_388335.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388336.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme NP_388337.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_388338.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299; Product type e: enzyme NP_388339.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840; Product type e: enzyme NP_388340.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388341.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388342.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15616571, 15849754, 16850406 NP_388343.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_388344.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type lp : lipoprotein NP_388345.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15043879, 18399999, 2835089; Product type e: enzyme NP_388346.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type r: regulator NP_388347.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type e: enzyme NP_388348.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor NP_388349.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type f: factor NP_388350.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type e: enzyme NP_388351.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665; Product type e: enzyme NP_388352.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15342585, 15583165, 16077134, 16885458; Product type f: factor NP_388353.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme NP_388354.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase NP_388355.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10671474, 12950928, 15466036, 9068644, 9658013; Product type e: enzyme NP_388356.1 Evidence 5: No homology to any previously reported sequences NP_388357.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388358.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12088660; Product type pr : regulator NP_388359.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388360.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388361.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_388362.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18761623; Product type cp: cell process NP_388363.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin NP_388364.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3269394; Product type h : extrachromosomal origin YP_003097681.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388365.1 Evidence 5: No homology to any previously reported sequences NP_388366.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388367.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388368.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388369.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388370.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388371.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388372.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388373.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388374.1 Evidence 5: No homology to any previously reported sequences NP_388375.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388376.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388377.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388378.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388379.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388380.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388381.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388382.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16105942; Product type r: regulator NP_388383.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type r: regulator NP_388384.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388385.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme NP_388386.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator NP_388387.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator NP_388388.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388389.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388390.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter YP_003097682.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_388391.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin YP_003097683.1 Evidence 5: No homology to any previously reported sequences NP_388392.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388393.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10517332, 12427936, 9914312, 9920884; Product type f: factor NP_388394.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388395.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388396.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator NP_388397.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388398.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388399.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388400.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388401.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388402.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388403.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388404.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388405.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388406.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1556068; Product type pe : enzyme NP_388407.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15159570; Product type e: enzyme NP_388408.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388409.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388410.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388411.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388412.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388413.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator YP_003097684.1 Evidence 5: No homology to any previously reported sequences NP_388414.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator NP_388415.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388416.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme NP_388417.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388418.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388419.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388420.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388421.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097685.1 Evidence 5: No homology to any previously reported sequences YP_003097686.1 Evidence 6: Doubtful CDS NP_388422.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type rc: receptor NP_388423.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type r: regulator NP_388424.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pt : transporter NP_388425.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7765103; Product type e : enzyme NP_388426.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10200972, 15849754, 16850406; Product type pm: membrane component NP_388427.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388428.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388429.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme NP_388430.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme NP_388431.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15306018, 15849754, 16850406, 17407181; Product type pe: enzyme NP_388432.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme NP_388433.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097687.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388434.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388435.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388436.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673; Product type f: factor NP_388437.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388438.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388439.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388440.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388441.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388442.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16109936; Product type t: transporter NP_388443.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16109936, 16850406; Product type pt: transporter NP_388444.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12644484, 16267290; Product type r : regulator NP_388445.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388446.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pm : membrane component NP_388447.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388448.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388449.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388450.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388451.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388452.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11011148, 12177332; Product type cp: cell process NP_388453.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388454.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557812; Product type lp : lipoprotein NP_388455.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 16030210, 16491025, 9335276; Product type e: enzyme NP_388456.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388457.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388458.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388459.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388460.1 Evidence 5: No homology to any previously reported sequences NP_388461.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12923093, 15849754, 16850406, 17935948; Product type t: transporter NP_388462.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 18177310; Product type t: transporter NP_388463.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter NP_388464.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 18177310; Product type t : transporter NP_388465.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18177310; Product type e: enzyme NP_388466.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310; Product type r: regulator NP_388467.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15018644, 18177310; Product type pe: enzyme NP_388468.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 10704478, 18177310, 3017192; Product type e: enzyme NP_388469.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310, 2694961, 7727534; Product type e: enzyme NP_388471.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_388472.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pe: enzyme NP_388473.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pf: factor NP_388474.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2828880; Product type e: enzyme NP_388475.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_388476.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11916677; Product type pt : transporter NP_388477.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_388478.1 modulates transcription in response to the NADH/NAD(+) redox state NP_388479.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 19049517; Product type t: transporter NP_388480.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775, 15187182, 15849754, 16850406, 19049517; Product type t : transporter NP_388481.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388482.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_388483.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_388484.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_388485.1 Evidence 5: No homology to any previously reported sequences YP_003097688.1 Evidence 5: No homology to any previously reported sequences NP_388487.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 12682299, 16014871, 16267290; Product type e: enzyme NP_388488.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 16267290; Product type e: enzyme NP_388490.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 15728999; Product type h: extrachromosomal origin NP_388491.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme NP_388492.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme NP_388493.1 Evidence 5: No homology to any previously reported sequences NP_388494.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388495.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11118449, 11390381, 12897001; Product type r: regulator NP_388496.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme NP_388497.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12897001; Product type t: transporter NP_388498.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388499.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11454200; Product type h: extrachromosomal origin NP_388500.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_388501.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388502.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_388503.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388504.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter NP_388505.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 18820069; Product type e: enzyme NP_388506.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388507.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component YP_003097689.1 Evidence 5: No homology to any previously reported sequences NP_388508.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388509.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pe : enzyme NP_388510.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388511.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11514528, 12637519, 16391148, 17242517, 18031270; Product type e: enzyme NP_388512.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16547045, 16850406, 8951816, 9677314; Product type t: transporter YP_003097690.1 Evidence 6: Doubtful CDS NP_388513.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388514.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388515.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388516.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388517.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_388518.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12923093, 15849754, 16850406, 3110131; Product type t : transporter NP_388519.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388520.3 Evidence 5: No homology to any previously reported sequences NP_388521.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388523.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388524.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12787499, 16138311, 9683488; Product type e : enzyme NP_388525.2 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_388526.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_388527.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_388528.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway NP_388529.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_388530.2 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_388531.2 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_388532.2 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_388533.2 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_388534.2 involved in de novo purine biosynthesis NP_388535.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_388536.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388537.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter YP_003097691.1 Evidence 5: No homology to any previously reported sequences NP_388538.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388539.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12073041; Product type lp : lipoprotein NP_388540.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388541.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388542.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer NP_388543.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 12682299, 14594837, 16267290; Product type e: enzyme NP_388544.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_388545.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type lp : lipoprotein NP_388546.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388547.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14708580, 410907, 9043134; Product type ph: phenotype NP_388548.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902719, 14996799, 15849754, 16850406, 17183215, 9701821; Product type t : transporter NP_388549.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_388550.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_388551.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_388552.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388553.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11709341, 15066026, 15941986; Product type t: transporter NP_388554.1 similar to YegS from E. coli NP_388555.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388556.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388557.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388558.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388559.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388560.2 Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin NP_388561.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388562.1 Evidence 5: No homology to any previously reported sequences YP_003097692.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388563.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388564.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388565.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878; Product type e: enzyme YP_003097693.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16553878; Product type pf : factor NP_388566.3 Evidence 4: Homologs of previously reported genes of unknown function NP_388567.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 19060142; Product type cp: cell process YP_054572.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388568.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388569.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388570.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process NP_388571.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process NP_388572.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process NP_388573.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388574.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388575.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388576.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_388577.1 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator NP_388578.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein NP_388579.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter NP_388580.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter NP_388581.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme NP_388582.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type r: regulator NP_388583.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691, 17957779; Product type e: enzyme NP_388584.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691 NP_388585.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pm: membrane component NP_388586.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein NP_388587.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme NP_388588.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme NP_388589.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17056685, 17449691, 17485082; Product type e: enzyme NP_388590.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388591.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921237; Product type lp: lipoprotein NP_388592.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter NP_388593.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter NP_388594.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388595.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388596.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388597.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388600.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388601.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388602.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388603.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388604.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388605.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388606.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11574077, 2544578; Product type pe: enzyme NP_388607.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11544192, 15187182, 17434969, 17483484; Product type e: enzyme NP_388608.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388609.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388610.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388611.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388612.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388613.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388614.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388615.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 2541919; Product type t: transporter NP_388616.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pe : enzyme NP_388617.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pr : regulator NP_388618.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10715006, 16109936; Product type pe: enzyme NP_388619.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388620.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator NP_388621.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075, 15849754, 16850406; Product type t: transporter NP_388622.1 Evidence 5: No homology to any previously reported sequences NP_388623.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 16109936; Product type pt: transporter NP_388624.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11976317; Product type pe : enzyme NP_388625.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388626.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388627.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388629.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388630.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672620; Product type t: transporter NP_388631.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16672620, 16850406; Product type t: transporter NP_388632.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter NP_388633.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter NP_388634.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388635.1 Evidence 6: Doubtful CDS NP_388636.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12089032; Product type f: factor NP_388637.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12823818, 8262178; Product type e: enzyme NP_388638.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12949159, 15849754, 16850406; Product type t: transporter NP_388639.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type rc: receptor NP_388640.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type r: regulator NP_388641.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388642.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12427932, 12533460, 12906362, 12949159, 15849754, 16842348, 16850406; Product type t: transporter NP_388643.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10972810; Product type pe : enzyme NP_388644.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11856757, 12220171, 16172391; Product type e: enzyme NP_388645.1 catalyzes the hydrolysis of acylphosphate NP_388646.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886751; Product type pc : carrier NP_388647.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388648.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388649.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368 NP_388650.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential NP_388651.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 8246840; Product type t: transporter NP_388652.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10658653; Product type pe : enzyme NP_388653.1 Evidence 5: No homology to any previously reported sequences NP_388655.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388656.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388657.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component NP_388658.1 Evidence 5: No homology to any previously reported sequences NP_388659.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor NP_388660.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor NP_388661.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8755887, 8917076, 8969503; Product type t: transporter NP_388662.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651129, 7751281, 8755887, 8917076, 9701821; Product type e: enzyme NP_388663.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8755887, 9829827; Product type r: regulator NP_388664.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme NP_388665.1 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate NP_388666.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 12354229, 16181642, 17257049, 17933887; Product type f: factor NP_388667.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16828913, 16850406; Product type t : transporter NP_388668.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388669.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme NP_388670.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210 NP_388671.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222749, 12794188, 15849754, 16850406; Product type pe: enzyme NP_388672.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388673.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388674.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388675.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388677.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388678.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388679.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15687192; Product type e: enzyme NP_388680.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388681.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter NP_388682.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388683.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_003097694.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388684.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710; Product type e: enzyme NP_388685.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388686.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388687.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme NP_388688.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme NP_388689.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 11274109; Product type e: enzyme NP_388690.1 E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_388691.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type r: regulator NP_388692.1 SASP H; spore coat; expressed in forespore compartment NP_388693.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388694.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388695.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388696.1 Evidence 5: No homology to any previously reported sequences NP_388697.1 Evidence 5: No homology to any previously reported sequences NP_388698.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388699.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10329789, 11489864, 15341727, 15670594, 17676871, 9765262; Product type e : enzyme NP_388700.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489864; Product type r: regulator NP_388701.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter NP_388702.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter NP_388703.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388704.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17407181; Product type e: enzyme NP_388705.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17407181; Product type e: enzyme NP_388706.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator NP_388707.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388708.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388709.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388710.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type rc: receptor NP_388711.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type r: regulator NP_388712.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388713.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388714.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388715.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 11073918, 17295427, 18326577; Product type r: regulator NP_388716.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11029590, 10913700; Product type e: enzyme NP_388717.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_388718.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16862575; Product type r: regulator NP_388719.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 16862575; Product type pt: transporter NP_388720.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15581359; Product type e: enzyme NP_388721.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388722.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator YP_003097695.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14702396, 15849754, 16299297, 16850406, 17042784, 2490162; Product type f: factor NP_388725.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter NP_388726.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter NP_388727.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter NP_388728.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388729.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme NP_388730.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388731.1 Evidence 5: No homology to any previously reported sequences NP_388732.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388733.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_388734.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388735.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter YP_054573.1 SASP K; found in the forespore compartment NP_388736.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388737.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388738.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16629676; Product type f: factor NP_388739.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388740.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8921856, 9636707; Product type pe: enzyme NP_388741.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388742.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10524235, 15849754, 16850406; Product type pe: enzyme NP_388743.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10463184; Product type e: enzyme NP_388744.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10463184 NP_388745.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_388746.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744043, 7592342, 9540829; Product type cp: cell process NP_388747.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388748.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388749.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_388750.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388751.3 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_054574.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10644761, 11349039, 12950915; Product type pe: enzyme NP_388753.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1580225, 16541078, 16925555; Product type r: regulator YP_054575.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388755.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388756.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9795118; Product type r : regulator NP_388757.2 Evidence 5: No homology to any previously reported sequences YP_003097696.1 Evidence 5: No homology to any previously reported sequences NP_388758.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388759.2 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_388760.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8972604; Product type pe : enzyme NP_388761.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1479343, 16321961, 8323536; Product type r: regulator NP_388762.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12486061, 16535198; Product type e: enzyme NP_388763.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type t: transporter NP_388764.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type f: factor NP_388765.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 15849754, 16513748, 16850406, 16885442, 9782504; Product type t : transporter NP_388766.2 catalyzes the release of sulfite from alkanesulfonates NP_388767.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388768.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_388769.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_003097697.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388771.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388772.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388773.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388774.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299; Product type pe : enzyme NP_388775.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388776.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388777.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388778.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 8626065; Product type e: enzyme NP_388779.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11988534, 12662922, 14523133; Product type f: factor NP_388780.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388781.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388782.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388783.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15754243; Product type pe : enzyme NP_388784.1 Evidence 5: No homology to any previously reported sequences NP_388785.1 Evidence 5: No homology to any previously reported sequences NP_388786.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388787.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388788.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pt : transporter NP_388789.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467, 7476193; Product type pt: transporter NP_388790.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 15870467, 16850406; Product type pt: transporter NP_388791.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12493834, 16352840; Product type f: factor NP_388792.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_388793.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388794.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter NP_388795.1 Evidence 5: No homology to any previously reported sequences NP_388796.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9611260; Product type lp : lipoprotein NP_388797.2 Evidence 5: No homology to any previously reported sequences NP_388799.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388800.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15292138; Product type e: enzyme NP_388801.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823805; Product type pe : enzyme NP_388802.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9814761; Product type pe : enzyme NP_388803.2 Evidence 5: No homology to any previously reported sequences NP_388804.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388805.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388806.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388807.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11082195; Product type pe : enzyme NP_388808.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549; Product type r: regulator NP_388809.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406; Product type t: transporter NP_388810.2 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_388811.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10633102, 2127799, 8825777, 9595668; Product type e: enzyme NP_388812.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15640167, 17662947; Product type e: enzyme NP_388813.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type rc: receptor NP_388814.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type r: regulator NP_388815.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15184374, 16816187; Product type e: enzyme NP_388816.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388817.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388818.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10206711, 14594841, 18761694, 18761696; Product type e: enzyme NP_388819.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16885456, 19006327; Product type r: regulator NP_388820.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388821.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 8144469; Product type ph: phenotype NP_388822.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12897025, 8830275; Product type e: enzyme NP_388823.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244, 16950129, 9457885; Product type e: enzyme NP_388824.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8045899; Product type r : regulator NP_388825.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 4211224, 8045898, 8045899; Product type e: enzyme NP_388826.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme NP_388827.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16621821, 16850406; Product type t : transporter NP_388828.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388829.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388830.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme NP_388831.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype NP_388832.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype NP_388833.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress NP_388834.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 15019785; Product type e: enzyme NP_388835.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 1557036, 17557823; Product type e: enzyme NP_388836.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pt : transporter NP_388837.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator NP_388838.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_388840.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_388841.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_388842.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12904550, 15849754, 16850406, 8844142; Product type f: factor NP_388843.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8012593; Product type pe : enzyme NP_388844.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388845.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12077558, 15849754, 16850406; Product type pm: membrane component NP_388846.1 Modulates the activities of several enzymes which are inactive in their acetylated form NP_388847.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388848.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17005988, 9003455; Product type e: enzyme NP_388849.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 11274110, 15849754, 16850406; Product type t: transporter NP_388850.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 1198853, 16159758; Product type f : factor NP_388851.1 Evidence 6: Doubtful CDS NP_388852.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter NP_388853.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter NP_388854.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388855.1 Evidence 5: No homology to any previously reported sequences NP_388856.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 3009398, 9572981; Product type cp: cell process NP_388857.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388858.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type f: factor NP_388859.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15231775; Product type f: factor NP_388860.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16684363 NP_388861.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388862.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290 NP_388864.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pe : enzyme NP_388865.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_388866.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 14987767, 15849754, 15919996, 16850406; Product type t: transporter NP_388867.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type t: transporter NP_388868.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type f: factor NP_388869.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_003097698.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388870.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 9106203; Product type t: transporter NP_388871.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 9106203; Product type t: transporter NP_388872.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme NP_388873.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme NP_388874.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates NP_388875.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523133; Product type ph: phenotype NP_388876.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12634326, 12682299, 14976191, 16516208; Product type lp: lipoprotein YP_003097699.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388878.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor NP_388879.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388880.1 hpr; ScoC; MarR family; protease production regulatory protein NP_388881.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11429463; Product type pm : membrane component YP_003097700.1 Evidence 5: No homology to any previously reported sequences NP_388882.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702295, 15849754, 16850406, 10735881; Product type t: transporter NP_388883.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine NP_388884.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15703176, 16934294, 9579061; Product type e : enzyme NP_388885.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 11807061, 8581172; Product type t: transporter NP_388886.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 15175311, 15849754, 16850406, 8581172; Product type t : transporter NP_388887.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10027970; Product type pe : enzyme NP_388888.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388889.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388890.1 Evidence 5: No homology to any previously reported sequences NP_388891.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388892.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11567005, 8335642; Product type e: enzyme NP_388893.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_388894.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_388895.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX NP_388896.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator NP_388897.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor NP_388898.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis NP_388899.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388901.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388902.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388903.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8634258; Product type t : transporter NP_388904.1 Evidence 6: Doubtful CDS NP_388905.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388906.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388907.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11790741; Product type pe : enzyme NP_388908.2 activates fatty acids by binding to coenzyme A NP_388909.1 Evidence 5: No homology to any previously reported sequences NP_388910.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9015299; Product type pe : enzyme NP_388911.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 14688235, 15205417, 17666034, 3108260, 9811547; Product type e : enzyme NP_388912.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388913.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12057962, 9643546; Product type pe: enzyme NP_388914.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter NP_388915.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10869096, 11827481, 17693564; Product type e: enzyme NP_388916.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_388917.1 activates fatty acids by binding to coenzyme A NP_388918.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12368242, 15849754, 16850406; Product type t: transporter NP_388919.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11481493, 12657801, 12962628, 15033535, 16819829, 17003124; Product type rc : receptor NP_388920.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388921.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388922.1 Evidence 5: No homology to any previously reported sequences NP_388923.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619, 16554821, 16907804, 17468244; Product type r: regulator NP_388924.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388925.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388926.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16267290, 16850406; Product type pt: transporter NP_388927.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pf : factor NP_388928.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290 NP_388929.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388930.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11309398, 14568161, 9325333; Product type e: enzyme NP_388931.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15121720, 7678243; Product type pe: enzyme NP_388932.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_388933.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17056753; Product type t: transporter NP_388934.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme NP_388935.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme NP_388936.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme NP_388937.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056753; Product type r: regulator NP_388938.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388939.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388940.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388941.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier NP_388942.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier NP_388943.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme NP_388944.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme NP_388945.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573, 7968921, 8493111; Product type e: enzyme NP_388946.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573; Product type e: enzyme NP_388947.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16780573; Product type pe : enzyme NP_388948.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388949.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388950.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388951.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388952.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388953.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process NP_388954.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme NP_388955.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process NP_388956.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388957.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388958.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10336490, 15205417, 17269748, 9004506, 9675284; Product type e: enzyme NP_388959.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388960.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme YP_054576.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388961.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388962.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388963.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator NP_388964.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8407808; Product type r : regulator NP_388965.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pe : enzyme NP_388966.2 Evidence 4: Homologs of previously reported genes of unknown function NP_388967.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_388968.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator NP_388970.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388971.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388972.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme NP_388973.2 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms NP_388974.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme NP_388975.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme NP_388976.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme NP_388977.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388978.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 11747447; Product type pe: enzyme NP_388979.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15109717, 15849754, 16850406; Product type pt: transporter NP_388980.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388981.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388982.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions NP_388983.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription NP_388984.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_388985.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388987.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388988.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 6289325 YP_003097701.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_388989.2 Evidence 5: No homology to any previously reported sequences NP_388990.1 Evidence 5: No homology to any previously reported sequences NP_388991.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672610, 1917867; Product type e: enzyme NP_388992.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388993.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_388994.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226659; Product type f : factor YP_003097702.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388995.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388996.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_388997.1 Evidence 4: Homologs of previously reported genes of unknown function NP_388999.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16956367; Product type pe: enzyme NP_389000.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389001.2 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_389002.2 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_389003.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_389004.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17012789; Product type e: enzyme NP_389005.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_389006.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_389007.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_389008.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389009.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389010.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389011.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type pe : enzyme NP_389012.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1203607; Product type lp: lipoprotein NP_389013.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10940045; Product type pf : factor NP_389014.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16391061 NP_389015.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_389016.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_389017.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389018.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter NP_389019.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter NP_389021.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter NP_389022.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter NP_389023.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389024.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_389025.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11083832, 11401703, 12823818, 1901616; Product type lp: lipoprotein NP_389026.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter NP_389027.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter NP_389028.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter NP_389029.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter NP_389030.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389031.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17158660, 17158663; Product type pe: enzyme NP_389032.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress NP_389033.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389034.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence NP_389035.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17630974; Product type s: structure NP_389036.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11741842; Product type e: enzyme YP_003097703.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389037.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17293416, 17908206; Product type pe: enzyme NP_389038.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15866723, 17293416; Product type pe: enzyme NP_389039.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389040.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456267, 16905149, 9642185; Product type pe: enzyme NP_389041.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389042.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18067544; Product type e: enzyme NP_389043.1 catalyzes the phosphorylation of NAD to NADP NP_389044.1 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_389045.1 asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate NP_389046.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389047.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15709744, 15858269, 16356850, 17618314, 18054064; Product type e: enzyme NP_389048.1 regulates the production of extracellular enzymes NP_389049.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12627963, 15105420, 9827558; Product type e: enzyme NP_389050.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 14567704, 14757766, 15489164; Product type c: carrier NP_389051.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_389052.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways NP_389053.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine NP_389054.2 Catalyzes a key regulatory step in fatty acid biosynthesis NP_389055.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process NP_389056.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process NP_389057.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766913, 7519271, 8509331; Product type cp: cell process NP_389058.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10400595, 10788508, 12031481, 7519271, 8509331; Product type cp: cell process NP_389059.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8509331; Product type cp: cell process NP_389060.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process NP_389061.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 15849754, 16850406; Product type cp: cell process YP_003097704.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097705.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523132; Product type h : extrachromosomal origin NP_389063.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 14702409; Product type cp: cell process NP_389064.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544244; Product type pe : enzyme YP_003097706.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315 NP_389066.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389067.1 similar to 2'-5' RNA ligase NP_389068.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389069.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity NP_389070.1 catalyzes the formation of L-homocysteine from cystathionine NP_389071.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2828880; Product type pe : enzyme NP_389072.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389073.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389074.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097707.1 Evidence 5: No homology to any previously reported sequences YP_003097708.1 Evidence 5: No homology to any previously reported sequences NP_389075.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389076.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535 NP_389077.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535 NP_389078.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7489895, 7704261; Product type pe: enzyme NP_389079.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389080.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_389081.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389082.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438772, 10960106; Product type r : regulator NP_389083.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627040, 10960106; Product type t: transporter NP_389084.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 7934877; Product type e: enzyme NP_389085.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389086.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389087.2 Evidence 5: No homology to any previously reported sequences NP_389088.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097709.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389089.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389090.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15491161, 15849754, 16850406; Product type e: enzyme NP_389091.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1391045, 1917883; Product type cp: cell process NP_389092.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 17878218; Product type e: enzyme NP_389093.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389094.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535 NP_389095.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389096.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406 NP_389097.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 1580552 NP_389098.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389099.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389100.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_389101.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12483591, 16513759; Product type pe: enzyme NP_389102.1 Evidence 5: No homology to any previously reported sequences NP_389103.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389104.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_003097710.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389105.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis NP_389106.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389107.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_389108.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389109.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478 NP_389110.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645; Product type r: regulator NP_389111.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645, 6816592; Product type e: enzyme NP_389112.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism NP_389113.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9882655; Product type t: transporter NP_389114.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16788182, 9579062, 9882655; Product type pe: enzyme NP_389115.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9579062, 9882655; Product type pe: enzyme NP_389116.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate NP_389117.1 Converts D-mannonate to D-mannuronate NP_389118.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8320243, 9579062, 9882655; Product type t: transporter NP_389119.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9579062, 9882655; Product type r: regulator NP_389120.1 catalyzes the formation of D-tagaturonate from D-altronate NP_389121.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9579062, 9882655; Product type e: enzyme NP_389122.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389123.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389124.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14757246; Product type e: enzyme NP_389125.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587784, 15805512, 15916600; Product type e: enzyme NP_389126.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 11587784, 16816200; Product type f: factor NP_389127.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15779043; Product type pe : enzyme NP_389128.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915, 9555893; Product type h: extrachromosomal origin NP_389129.1 Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin NP_389130.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin NP_389131.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin NP_389132.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267290, 8760915; Product type h: extrachromosomal origin NP_389133.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin YP_003097711.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389134.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389135.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097712.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389136.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389137.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915; Product type h : extrachromosomal origin NP_389138.1 Positive regulatory protein that acts at the late promoter PL NP_389139.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8083174; Product type e: enzyme NP_389140.1 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_389141.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_389142.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389143.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure YP_003097713.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389144.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389145.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389146.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097714.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389147.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389148.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389149.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097715.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389150.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389151.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389152.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389153.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389154.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389155.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389156.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097716.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389158.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389159.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389160.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389161.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin NP_389162.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin NP_389163.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2110147, 9555893; Product type h: extrachromosomal origin NP_389164.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin NP_389165.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520; Product type f: factor NP_389166.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520, 18096016; Product type f: factor NP_389167.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter NP_389168.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696772; Product type pf : factor NP_389169.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389170.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme NP_389171.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389172.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389173.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10692364, 11133960, 11555295, 12823817; Product type e: enzyme NP_389174.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_389175.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069674, 11473256; Product type e: enzyme NP_389176.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter NP_389177.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter NP_389178.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7536291; Product type t : transporter NP_389179.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 7783641, 8793880; Product type lp: lipoprotein NP_389180.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10428950, 15101989; Product type pe: enzyme NP_389181.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11747447, 15101989; Product type e: enzyme NP_389182.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type e: enzyme NP_389183.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pt : transporter NP_389184.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389185.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389186.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389187.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine NP_389188.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389189.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389190.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389191.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme NP_389192.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter NP_389193.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter NP_389194.2 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_389195.2 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_389196.2 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_389197.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418552, 17502599; Product type e: enzyme NP_389198.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11983871, 17502599, 18363800; Product type r: regulator NP_389199.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11418552, 18084074, 9696771; Product type e : enzyme YP_003097717.1 Evidence 5: No homology to any previously reported sequences NP_389200.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11101664, 15180998; Product type e: enzyme NP_389201.2 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_389202.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 3087947; Product type e: enzyme NP_389203.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor NP_389204.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter NP_389205.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16291685, 16356850; Product type t: transporter NP_389206.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter NP_389207.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15451668, 16291685, 16356850; Product type f: factor NP_389208.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator NP_389209.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_389210.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389211.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17209068; Product type ph : phenotype NP_389212.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389213.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15096624; Product type t: transporter NP_389214.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10231480, 12823818, 15916606, 16547045, 17085574, 17183219; Product type r : regulator NP_389215.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441 NP_389216.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441 NP_389217.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389218.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389219.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389220.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389221.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389222.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389223.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA NP_389224.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11095673, 12215643, 16497325, 16780573; Product type e: enzyme YP_054577.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11728710; Product type prc : receptor NP_389226.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389227.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter NP_389228.1 Heat shock-induced NP_389229.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17185538; Product type f: factor NP_389230.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3009397, 3112127, 3121585, 9852018; Product type f: factor NP_389231.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389232.1 metalloprotease NP_389233.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406; Product type t: transporter YP_003097718.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389234.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389235.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_389236.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 12169614, 16166384; Product type rc: receptor NP_389237.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2308822, 2359121; Product type e: enzyme NP_389238.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway NP_389239.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway NP_389240.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12022921; Product type pe : enzyme NP_389241.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however NP_389242.1 converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage NP_389243.1 converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage NP_389244.1 converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage NP_389245.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10704478, 11371200, 12022880, 12402029, 15102328; Product type e: enzyme NP_389246.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389247.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15057450, 15916600; Product type e: enzyme NP_389248.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389249.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 16166384, 10411754; Product type e: enzyme NP_389250.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17725564; Product type r: regulator NP_389251.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_389252.1 With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. NP_389253.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788169, 16899079, 11069659, 9987115, 10320580; Product type e: enzyme NP_389254.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836, 15849754, 16850406; Product type pt: transporter NP_389255.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14660578, 16199558, 17384645, 18491386; Product type e: enzyme NP_389256.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558, 18259064; Product type e: enzyme NP_389257.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558; Product type e : enzyme NP_389258.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis NP_389259.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pr : regulator NP_389260.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme NP_389261.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 16683018; Product type f: factor YP_003097719.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389262.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme YP_003097720.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme NP_389263.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389264.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097721.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389265.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12177332, 12950927; Product type e : enzyme NP_389266.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15686839, 15849754, 16850406; Product type m: membrane component NP_389267.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15322369, 15342593; Product type e: enzyme NP_389268.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12180919, 15802251; Product type t: transporter NP_389269.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7770058; Product type pe : enzyme NP_389270.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389271.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974121, 15155854, 17074746; Product type r: regulator NP_389272.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1447219, 14527945, 15849754, 16850406, 8418852, 8432747, 9593197; Product type t: transporter NP_389273.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217795, 12411438, 14527945, 15126459, 16267306, 17085448, 17142398; Product type f: factor NP_389274.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902727, 15155854, 15670601, 3106335; Product type e: enzyme NP_389275.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 9009064, 9323362; Product type r: regulator NP_389276.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 11053385, 11470912, 17293412, 9733691; Product type e: enzyme NP_389277.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389278.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11722727, 12603740, 15317802, 9721285; Product type rc: receptor NP_389279.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389280.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389281.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990; Product type e: enzyme NP_389282.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11734624, 14629015, 17350039; Product type cp: cell process NP_389283.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12670965; Product type e: enzyme YP_003097722.1 Evidence 6: Doubtful CDS NP_389284.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11553614, 12864845, 14731274, 14993307; Product type r: regulator NP_389285.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389286.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389287.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148; Product type cp: cell process NP_389288.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389289.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme YP_003097723.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250 YP_003097724.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389291.1 Evidence 5: No homology to any previously reported sequences NP_389292.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389293.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389294.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16165328; Product type pe : enzyme NP_389295.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389296.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717 NP_389297.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636591, 16352834, 16395550; Product type r: regulator NP_389298.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_389299.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229 NP_389300.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15449930, 17127770; Product type e: enzyme NP_389301.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368155, 11910040, 12682299, 14627808; Product type e: enzyme NP_389302.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14627808, 17093042; Product type e : enzyme NP_389303.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389304.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12626684; Product type pt : transporter NP_389305.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389306.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16418167; Product type e: enzyme NP_389307.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619; Product type r: regulator NP_389308.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949 NP_389309.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 10978347; Product type e: enzyme NP_389310.1 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways NP_389311.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 11428898, 12006571; Product type e : enzyme NP_389312.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12719427, 9219527; Product type c : carrier NP_389313.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669; Product type e: enzyme NP_389314.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669, 17223713; Product type e : enzyme NP_389315.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_389316.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_389317.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389318.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter NP_389319.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter NP_389320.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter NP_389321.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858; Product type r: regulator NP_389322.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858, 168069; Product type e: enzyme NP_389323.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 118007, 200418; Product type t: transporter NP_389324.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10198007, 11283286, 12897006, 9325333; Product type e: enzyme NP_389325.1 Evidence 5: No homology to any previously reported sequences NP_389326.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10816464; Product type t: transporter NP_389327.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15966718, 17229734; Product type e: enzyme NP_389328.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16088219, 9362117; Product type e: enzyme NP_389329.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389330.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16950129; Product type f: factor NP_389331.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 17720793; Product type r: regulator NP_389332.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 7836330; Product type e: enzyme NP_389333.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389334.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter NP_389335.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8550522; Product type e : enzyme NP_389336.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15831787, 17005971, 17229210, 17512403, 18713320; Product type e : enzyme NP_389337.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389338.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389339.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_003097725.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389340.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16684363; Product type pf : factor NP_389341.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 1784816, 9352926, 9588797; Product type e: enzyme NP_389342.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme NP_389343.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme NP_389344.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_389345.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1936936; Product type s : structure YP_003097726.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389346.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9723923; Product type e : enzyme NP_389347.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389348.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389349.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389350.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11914086, 16682444; Product type e: enzyme NP_389351.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389352.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389353.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 2128597, 6090407, 8436952; Product type e: enzyme NP_389354.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307 NP_389355.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307 NP_389356.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator NP_389357.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator NP_389358.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389359.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389360.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11683274, 12399512, 9642082; Product type e : enzyme NP_389361.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389362.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389363.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_389364.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12762842; Product type pf : factor NP_389365.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389366.1 catalyzes the formation of glutamate from glutamine NP_389367.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein NP_389368.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12626683, 15849754, 16850406, 9622350; Product type t: transporter NP_389369.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate NP_389370.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12206660, 15491161, 15849754, 16321940, 16850406; Product type e: enzyme NP_389371.1 converts protoheme IX and farnesyl diphosphate to heme O NP_389372.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1685007, 1847686, 9829923, 9882689; Product type e: enzyme NP_389373.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15849754, 1685007, 16850406, 1847686; Product type e: enzyme NP_389374.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1847686; Product type e: enzyme NP_389375.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1847686; Product type e : enzyme NP_389376.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766920, 15849754, 16305244, 16850406; Product type f: factor NP_389377.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389378.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389379.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389380.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389381.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389382.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10712692, 15175311, 15661000; Product type pr: regulator NP_389383.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389384.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme NP_389385.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_389386.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type cp: cell process NP_389387.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389388.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389389.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097727.1 Evidence 5: No homology to any previously reported sequences NP_389390.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11700356 NP_389391.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_389392.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15621419; Product type cp: cell process NP_389393.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389394.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_389395.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16169927; Product type pf : factor NP_389396.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_389397.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10572301, 16849811; Product type e: enzyme NP_389398.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10792716, 10844672, 11994149, 16549676, 16936019, 17020588; Product type cp : cell process NP_389399.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14731276, 8636036; Product type cp: cell process NP_389400.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8244929, 8289242, 9006059; Product type cp: cell process NP_389401.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_389402.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_389403.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_389404.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16484183, 16850406, 2509435, 9622350; Product type cp: cell process NP_389405.2 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_389406.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_389407.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10852898, 12682299, 15659156, 16618922, 16936019, 16936026; Product type cp : cell process NP_389408.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16484183 NP_389409.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389410.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1569582, 15849754, 16850406; Product type pm: membrane component NP_389411.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15153768, 16159787, 16796675, 17015652; Product type cp: cell process NP_389412.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_389413.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1368833, 15205417, 15375126, 1938892, 2106512; Product type e: enzyme NP_389414.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498732, 15849754, 16850406, 7585939, 7729420, 9573195, 9663680; Product type e: enzyme NP_389415.2 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation NP_389416.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin NP_389417.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pt : transporter NP_389418.2 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine NP_389419.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060 NP_389420.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389421.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14526035 NP_389422.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526035, 16420366, 16796675, 18782755; Product type cp: cell process NP_389423.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14526035; Product type f: factor NP_389424.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10093218, 14526035; Product type f: factor NP_389425.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950914, 14526035, 15165232, 15554965, 16885474; Product type f: factor NP_389426.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase; some organisms carry two different copies of this enzyme NP_389427.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987 NP_389428.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_389429.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15078091, 15928344, 17188032; Product type e: enzyme NP_389430.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_389431.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8206848; Product type t : transporter NP_389432.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_389433.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16522191, 7516791; Product type e: enzyme NP_389434.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_389435.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_389436.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) NP_389437.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits NP_389438.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_389439.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_389440.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12072441, 16267287, 11004190, 10094622; Product type e: enzyme NP_389441.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10784039, 15849754, 16850406, 11004190, 10094622; Product type t : transporter NP_389442.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms NP_389443.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1332767, 11004190, 10094622; Product type e : enzyme NP_389444.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1906874, 11004190, 10094622; Product type e : enzyme NP_389445.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme NP_389446.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme NP_389447.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11238985, 17586671; Product type pf: factor NP_389448.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12161109; Product type t: transporter NP_389449.1 Evidence 4: Homologs of previously reported genes of unknown function NP_570902.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389450.2 Essential for recycling GMP and indirectly, cGMP NP_389451.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_389452.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11278255, 11358972, 12140293, 14686929, 15530362; Product type e: enzyme NP_389453.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_389454.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_389455.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10858337, 9843487; Product type e: enzyme NP_389456.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14656444; Product type e: enzyme NP_389457.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_389458.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 10986276; Product type e: enzyme NP_389459.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 18984160, 10986276; Product type e: enzyme NP_389460.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity NP_389461.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_389462.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15150256, 16291685; Product type e: enzyme NP_389463.1 involved in the production of the spore cortex and coat NP_389464.1 required for 70S ribosome assembly NP_389465.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389466.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16647083; Product type pe : enzyme NP_389467.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 8385012, 9244285; Product type e : enzyme NP_389468.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 2504697; Product type e: enzyme NP_389469.1 catalyzes branch migration in Holliday junction intermediates NP_389470.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria NP_389471.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_389472.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14586097; Product type e: enzyme NP_389473.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12655455, 12682299, 8759840; Product type e: enzyme NP_389474.1 carries the fatty acid chain in fatty acid biosynthesis NP_389475.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_389476.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137, 15987505, 16272394, 9701812; Product type e : enzyme NP_389477.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15995216, 16705751, 11021934, 11123669, 11166993; Product type rc : receptor NP_389478.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535 NP_389479.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11274114 NP_389480.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 10658653, 11123669, 7511896, 8662730, 10222262, 10224127; Product type cp: cell process NP_389481.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_389482.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389483.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389484.1 Essential for efficient processing of 16S rRNA NP_389485.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_389486.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_389487.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) NP_389488.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_389489.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389490.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389491.1 catalyzes the interconversion of succinyl-CoA and succinate NP_389492.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_389493.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 16014871, 16978360, 17803906, 18045469, 7768823; Product type f: factor NP_389494.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_389495.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine NP_389496.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_389497.1 heat shock protein involved in degradation of misfolded proteins NP_389498.1 heat shock protein involved in degradation of misfolded proteins NP_389499.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor NP_389500.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella NP_389501.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod NP_389502.1 forms a junction between the M-ring and FlgB during flagella biosynthesis NP_389503.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod NP_389504.1 One of three proteins involved in switching the direction of the flagellar rotation NP_389505.2 binds to and inhibits the function of flagella specific ATPase FliI NP_389506.2 involved in type III protein export during flagellum assembly NP_389507.1 rod/hook and filament chaperone NP_389508.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_389509.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16630628, 16949608; Product type f: factor NP_389510.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod NP_389511.2 makes up the distal portion of the flagellar basal body rod YP_003097728.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_389512.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring NP_389513.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation NP_389514.1 One of three proteins involved in switching the direction of the flagellar rotation NP_389515.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 12864845, 12920116, 14749334; Product type r: regulator NP_389516.1 possible structural component of the flagellum that anchors the rod to the membrane NP_389517.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus NP_389518.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus NP_389519.2 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus NP_389520.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export NP_389521.2 membrane protein involved in the flagellar export apparatus NP_389522.1 positive regulator of class III flagellar genes NP_389523.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15361076; Product type f: factor NP_389524.2 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins NP_389525.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12094812, 12864845, 12920116, 15451661, 16045621; Product type rc: receptor NP_389526.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12864845, 15451661, 1624415, 8169223, 8169224; Product type r: regulator NP_389527.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12920116, 14749334, 14993307, 15546616, 16469702; Product type cp: cell process NP_389528.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15546616, 16469702; Product type cp: cell process NP_389529.1 expressed in late exponential phase; controls the expression of genes coding cell surface proteins involved in chemotaxis, flagellar assembly, and autolysis NP_389530.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 15175317; Product type r: regulator NP_389531.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_389532.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_389533.2 Catalyzes the phosphorylation of UMP to UDP NP_389534.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_389535.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_389536.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406; Product type e : enzyme NP_389537.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_389538.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127, 15496982, 15520285, 16014871, 16899079; Product type e: enzyme NP_389539.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_389540.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity NP_389541.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_389542.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_389543.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11679764, 12682299; Product type pf: factor NP_389544.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15130481, 15361074; Product type f : factor NP_389545.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_389546.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389547.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_389548.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_389549.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_389550.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_389551.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572137, 15805522, 8636041, 8825779, 9179491; Product type e: enzyme NP_389552.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227; Product type pe : enzyme NP_389553.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10666719, 10974125; Product type e: enzyme NP_389554.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389555.1 catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance NP_389556.1 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme NP_389557.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_389558.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive NP_389559.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_389560.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15831787, 18713320; Product type e: enzyme NP_389561.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 15189290; Product type f: factor YP_003097729.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389562.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11062134, 11778051, 12618465, 16430687, 17139259, 17322320, 18160039; Product type cp: cell process NP_389563.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389564.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389566.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389568.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389569.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_389570.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389573.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12682299 NP_389574.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15743965, 15849754, 16514141, 16850406; Product type e: enzyme NP_389575.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438773, 11703670; Product type r : regulator NP_389576.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_389577.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762009, 15758244; Product type e: enzyme NP_389578.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP NP_389579.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389580.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16428420, 7559352; Product type r: regulator NP_389581.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism NP_389582.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine NP_389583.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_389584.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000; Product type r: regulator NP_389585.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14563859, 14973022, 17172339; Product type cp: cell process NP_389586.2 This protein performs the mismatch recognition step during the DNA repair process NP_389587.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_054578.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389588.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389589.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389590.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389591.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme NP_389592.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme NP_389593.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme NP_570904.1 Acyl carrier proteins are involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; this ACP may be involved in the biosynthesis of lipopeptide antibiotics NP_389594.2 involved in polyketide production NP_389595.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme NP_389596.1 involved in polyketide synthesis NP_389597.2 involved in polyketide production NP_389598.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16460000, 16707694; Product type e: enzyme NP_389600.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561, 17042494; Product type e: enzyme NP_389601.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15480790; Product type e: enzyme NP_389602.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16460000; Product type e: enzyme NP_389604.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 15480790; Product type e: enzyme NP_389605.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17482575; Product type e: enzyme NP_389606.3 Evidence 4: Homologs of previously reported genes of unknown function NP_389607.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389608.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589719, 16267290, 17884659; Product type e: enzyme NP_389609.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type h : extrachromosomal origin NP_389610.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme NP_389611.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 15849754, 16750162, 16850406; Product type t: transporter NP_389612.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 11104814, 17516673; Product type t: transporter NP_389613.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389614.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389615.2 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_389616.1 Stimulates the elongation of poly(A) tails NP_389617.1 Evidence 5: No homology to any previously reported sequences NP_389618.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389619.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_389620.1 Catalyzes the rate-limiting step in dNTP synthesis NP_389621.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_389622.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885274; Product type pe : enzyme NP_389623.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10945275, 10974124, 11375403, 16042392; Product type e: enzyme NP_389624.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8464402; Product type cp: cell process NP_389625.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389626.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389627.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12374841, 16547045, 16885465, 9287005; Product type r: regulator NP_389628.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719184, 12142436, 13737, 16055443, 16885465; Product type e: enzyme NP_389629.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389630.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389631.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389632.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389633.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389634.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389635.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389636.1 Evidence 5: No homology to any previously reported sequences NP_389637.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097730.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389638.3 Evidence 4: Homologs of previously reported genes of unknown function NP_389639.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16684115, 16850406, 17183216; Product type pt: transporter NP_389640.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16684115, 2440680, 6413490, 7816035, 9286998, 9973552; Product type e : enzyme NP_389641.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1588910, 1719948, 2544559, 7559331; Product type r: regulator NP_389642.2 catalyzes the interconversion of D-xylose to D-xylulose NP_389643.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1660563, 8866023; Product type e: enzyme NP_389644.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type e: enzyme NP_389645.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389646.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10348844, 18399999; Product type e: enzyme NP_389648.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389649.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15939294, 16908222, 17169987; Product type h: extrachromosomal origin NP_389650.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816, 18065538; Product type f: factor NP_389651.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_389652.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097731.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_389653.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10788508, 11741866, 14762008, 18065538, 2821284; Product type s: structure NP_389654.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775; Product type t: transporter NP_389655.1 Evidence 5: No homology to any previously reported sequences NP_389656.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389657.2 Evidence 5: No homology to any previously reported sequences NP_389658.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor NP_389659.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component NP_389660.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type lp : lipoprotein NP_389661.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389662.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389663.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389664.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389665.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389666.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389667.1 catalyzes resistance to fosfomycin by the addition of a thiol cofactor NP_389668.1 Represses a number of genes involved in the response to DNA damage NP_389669.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12581363, 16267290, 16549676; Product type cp: cell process NP_389670.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12581363, 16267290, 17020588; Product type cp: cell process NP_389671.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750 NP_389672.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 12882400; Product type e: enzyme NP_389673.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389674.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389675.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme NP_389676.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16771673, 16850406; Product type e: enzyme NP_389677.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554; Product type pr : regulator NP_389678.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554, 15849754, 16850406; Product type pm: membrane component NP_389679.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389680.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673, 9068633; Product type m: membrane component NP_389681.1 SASP P; found in forespore compartment NP_389682.1 SASP O; found in forespore compartment NP_389683.1 Catalyzes the conversion of citrate to isocitrate NP_389684.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15342593; Product type pe : enzyme YP_003097732.1 Evidence 4: Homologs of previously reported genes of unknown function YP_054579.2 SASP N; found in forespore compartment NP_389685.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type f: factor YP_054580.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389687.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389688.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389689.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX NP_389690.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389691.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_389692.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_389693.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389694.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12823818, 15849754, 16850406, 8969507; Product type t: transporter NP_389695.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15139916, 3024130, 7710279; Product type e: enzyme NP_389696.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389697.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17028274; Product type e: enzyme NP_389698.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1938968; Product type e : enzyme NP_389699.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389700.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8320212; Product type pe : enzyme NP_389701.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389702.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389703.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389704.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_389705.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_003097733.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_389706.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_389707.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12535077, 15213221; Product type e: enzyme NP_389708.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8655474; Product type e: enzyme NP_389709.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389710.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type ps : structure NP_389711.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389712.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486459, 9889147, 10471562; Product type e: enzyme NP_389713.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme NP_389714.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme NP_389715.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme NP_389716.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme NP_389717.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160090, 14731276, 9733705, 9864321; Product type e: enzyme NP_389718.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9733705; Product type pe : enzyme NP_389719.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389720.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483219, 17581128, 18761694; Product type f: factor NP_389721.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389722.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16880568; Product type pe : enzyme NP_389723.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8763966; Product type e : enzyme NP_389724.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17526699; Product type r: regulator NP_389725.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pe : enzyme NP_389726.2 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_389727.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14570271, 39113, 6769440, 6774712, 7559359; Product type e: enzyme NP_389728.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15150225, 17134717, 2548995; Product type r: regulator NP_389729.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_389730.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme NP_389731.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11313334, 15657033, 16822523, 17376071, 17521668; Product type f: factor NP_389732.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_389733.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389734.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389735.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme NP_389736.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 15849754, 16513748, 16850406; Product type t: transporter NP_389737.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 1660563, 10094622; Product type e: enzyme NP_389738.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 12193636, 10094622; Product type pe: enzyme NP_389739.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 17114254, 2170332; Product type e : enzyme NP_389740.1 Evidence 5: No homology to any previously reported sequences NP_389741.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_054581.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389742.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pf : factor NP_389743.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389744.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 18971341; Product type e: enzyme NP_389745.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389746.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1731776, 2018526, 2185758, 7764549; Product type e: enzyme NP_389747.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097734.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_389748.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11546787, 14697267, 15628860; Product type e: enzyme NP_389749.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389750.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389751.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097735.1 Evidence 5: No homology to any previously reported sequences NP_389752.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_389753.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8631706; Product type pf : factor NP_389754.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406 NP_389755.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389756.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389757.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389758.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter NP_389759.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type ph: phenotype NP_389760.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16181642; Product type pf : factor NP_389761.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16944130, 7789815; Product type e: enzyme NP_389762.1 Evidence 5: No homology to any previously reported sequences NP_389763.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821; Product type h : extrachromosomal origin NP_389764.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389765.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16517552, 8628241; Product type e: enzyme YP_003097736.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389766.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin NP_389767.2 Evidence 5: No homology to any previously reported sequences NP_389768.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389769.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389770.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097737.1 Evidence 5: No homology to any previously reported sequences YP_003097738.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389771.1 Evidence 5: No homology to any previously reported sequences YP_003097739.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389772.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme NP_389773.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587781, 16816200; Product type r: regulator NP_389774.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389775.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12137951; Product type h : extrachromosomal origin NP_389776.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951 NP_389777.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389778.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15128444; Product type pe : enzyme NP_389779.1 Evidence 5: No homology to any previously reported sequences NP_389780.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389781.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389782.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389783.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389784.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389785.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658654, 10816431, 13129613, 15856219, 17372352; Product type f: factor NP_389786.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator NP_389787.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme NP_389788.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389789.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389790.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389791.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389792.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8990290; Product type f: factor NP_389793.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator NP_389794.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389795.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389796.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389797.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389798.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389799.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12207704, 15247225, 15711796, 16105701; Product type e: enzyme NP_389800.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type rc : receptor NP_389801.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type r : regulator NP_389802.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17307850; Product type pf : factor NP_389803.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886746; Product type pe : enzyme NP_389804.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds NP_389805.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor NP_389806.1 Evidence 5: No homology to any previously reported sequences YP_003097740.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389808.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11150673; Product type ps : structure NP_389809.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389810.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389811.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389812.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389813.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389814.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2253626; Product type e: enzyme NP_389815.1 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_389816.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389817.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_389818.2 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA NP_389819.3 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide NP_389820.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389821.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15491156; Product type pe : enzyme NP_389822.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15897454; Product type lp: lipoprotein NP_389823.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244; Product type e: enzyme NP_389824.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389825.3 Evidence 4: Homologs of previously reported genes of unknown function NP_389826.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones NP_389827.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor YP_054582.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15136574; Product type pe : enzyme NP_389829.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097741.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389830.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_054583.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17720779; Product type s: structure NP_389832.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389833.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 3020045; Product type pt: transporter NP_389834.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389835.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17158660, 18208493; Product type r: regulator NP_389836.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389837.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme NP_389838.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme YP_003097742.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389839.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823818, 15849754, 16850406; Product type pt: transporter NP_389840.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10974125, 14526016, 8996100; Product type e : enzyme NP_389841.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389842.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389843.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187182, 8631706; Product type e: enzyme NP_389844.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_003097743.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389845.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389846.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_389847.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097744.1 Evidence 5: No homology to any previously reported sequences NP_389848.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389849.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097745.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389850.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629195, 10839984, 11148055, 18307109; Product type e: enzyme NP_389851.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389852.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine NP_389853.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389854.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389855.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_003097746.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389856.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process NP_389857.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process NP_389858.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process NP_389859.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702409, 15621419, 759239; Product type cp: cell process NP_389860.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process NP_389861.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10679209, 12111145, 12556126; Product type e: enzyme NP_389863.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin NP_389864.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin NP_389865.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389866.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389867.1 Evidence 5: No homology to any previously reported sequences NP_389868.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389869.1 Evidence 5: No homology to any previously reported sequences NP_389870.1 Evidence 5: No homology to any previously reported sequences NP_389871.1 Evidence 5: No homology to any previously reported sequences NP_389872.1 Evidence 5: No homology to any previously reported sequences NP_389873.1 Evidence 5: No homology to any previously reported sequences NP_389874.1 Evidence 5: No homology to any previously reported sequences NP_389875.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389876.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 12234173, 14526021, 15150240; Product type s: structure NP_389878.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389879.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389880.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097747.1 Evidence 5: No homology to any previously reported sequences NP_389881.1 Evidence 5: No homology to any previously reported sequences NP_389882.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389883.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11375514, 15939294; Product type h: extrachromosomal origin NP_389884.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16885274, 17395719; Product type h: extrachromosomal origin NP_389886.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_389885.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type h: extrachromosomal origin NP_389888.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type e: enzyme NP_389889.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_389890.1 Evidence 5: No homology to any previously reported sequences NP_389891.1 Evidence 5: No homology to any previously reported sequences NP_389892.1 Evidence 5: No homology to any previously reported sequences NP_389893.1 Evidence 5: No homology to any previously reported sequences NP_389894.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389895.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389896.1 Evidence 5: No homology to any previously reported sequences NP_389897.1 Evidence 5: No homology to any previously reported sequences NP_389898.1 Evidence 5: No homology to any previously reported sequences NP_389899.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389900.1 Evidence 5: No homology to any previously reported sequences NP_389901.1 Evidence 5: No homology to any previously reported sequences; Product type h: extrachromosomal origin NP_389902.1 Evidence 5: No homology to any previously reported sequences NP_389903.1 Evidence 5: No homology to any previously reported sequences NP_389904.1 Evidence 5: No homology to any previously reported sequences NP_389905.1 Evidence 5: No homology to any previously reported sequences NP_389906.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389907.1 Evidence 2b: Function of strongly homologous gene; Product type h: extrachromosomal origin NP_389908.1 Evidence 6: Doubtful CDS NP_389909.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389910.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389911.1 Evidence 5: No homology to any previously reported sequences NP_389912.1 Evidence 5: No homology to any previously reported sequences NP_389913.1 Evidence 5: No homology to any previously reported sequences NP_389914.1 Evidence 5: No homology to any previously reported sequences NP_389915.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389916.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389917.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389918.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389919.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389920.1 Evidence 5: No homology to any previously reported sequences NP_389921.1 Evidence 5: No homology to any previously reported sequences NP_389922.1 Evidence 5: No homology to any previously reported sequences NP_389923.1 Evidence 5: No homology to any previously reported sequences NP_389924.1 Evidence 5: No homology to any previously reported sequences NP_389925.1 Evidence 5: No homology to any previously reported sequences NP_389926.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389927.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_389928.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389929.1 Evidence 5: No homology to any previously reported sequences NP_389930.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_389931.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389932.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA NP_389933.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389934.1 Evidence 5: No homology to any previously reported sequences NP_389935.1 Evidence 5: No homology to any previously reported sequences NP_389936.1 Evidence 5: No homology to any previously reported sequences NP_389937.1 Evidence 5: No homology to any previously reported sequences NP_389938.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389939.1 Evidence 5: No homology to any previously reported sequences NP_389940.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_389941.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389942.1 Evidence 5: No homology to any previously reported sequences NP_389943.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389944.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389945.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389946.1 Evidence 5: No homology to any previously reported sequences NP_389947.1 Evidence 5: No homology to any previously reported sequences NP_389948.1 Evidence 5: No homology to any previously reported sequences NP_389949.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2661831; Product type pr : regulator NP_389950.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389951.1 Evidence 5: No homology to any previously reported sequences NP_389952.1 Evidence 5: No homology to any previously reported sequences NP_389953.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389954.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389955.1 Evidence 5: No homology to any previously reported sequences NP_389956.1 Evidence 5: No homology to any previously reported sequences NP_389957.1 Evidence 5: No homology to any previously reported sequences NP_389958.1 Evidence 5: No homology to any previously reported sequences NP_389959.1 Evidence 5: No homology to any previously reported sequences NP_389960.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389961.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389962.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389963.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11208805; Product type pe : enzyme NP_389964.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389965.1 Evidence 5: No homology to any previously reported sequences NP_389966.1 Evidence 5: No homology to any previously reported sequences NP_389967.1 Evidence 5: No homology to any previously reported sequences NP_389968.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389969.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389970.1 Evidence 5: No homology to any previously reported sequences NP_389971.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389972.1 Evidence 5: No homology to any previously reported sequences NP_389973.1 Evidence 5: No homology to any previously reported sequences NP_389974.1 Evidence 5: No homology to any previously reported sequences YP_003097748.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097749.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389976.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_389977.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389978.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389979.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389980.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389981.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389982.1 Evidence 5: No homology to any previously reported sequences YP_003097750.1 Evidence 5: No homology to any previously reported sequences NP_389983.1 Evidence 5: No homology to any previously reported sequences NP_389984.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_389985.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_389986.1 Evidence 5: No homology to any previously reported sequences NP_389987.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389988.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_389989.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389990.2 Evidence 4: Homologs of previously reported genes of unknown function NP_389991.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389992.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_389993.1 Evidence 5: No homology to any previously reported sequences NP_389994.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774886; Product type pe : enzyme NP_389995.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389996.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389997.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389998.1 Evidence 4: Homologs of previously reported genes of unknown function NP_389999.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390000.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390001.1 Evidence 5: No homology to any previously reported sequences NP_390002.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390003.1 Evidence 5: No homology to any previously reported sequences NP_390004.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390005.1 Evidence 5: No homology to any previously reported sequences YP_003097751.1 Evidence 5: No homology to any previously reported sequences NP_390006.1 Evidence 5: No homology to any previously reported sequences NP_390007.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390008.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390009.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390010.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390011.1 Evidence 5: No homology to any previously reported sequences NP_390012.1 Evidence 5: No homology to any previously reported sequences NP_390013.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390014.1 Evidence 5: No homology to any previously reported sequences NP_390015.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097752.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276 NP_390016.1 Evidence 5: No homology to any previously reported sequences NP_390017.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_390018.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931330; Product type h: extrachromosomal origin NP_390019.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390020.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin NP_390021.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390022.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390023.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390024.1 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin NP_390025.1 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin NP_390026.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 17322187; Product type h: extrachromosomal origin NP_390027.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16850406; Product type h: extrachromosomal origin NP_390028.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pe : enzyme NP_390029.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949; Product type h: extrachromosomal origin NP_390030.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type t: transporter NP_390031.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type h: extrachromosomal origin NP_390032.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 19047653; Product type cp: cell process NP_390033.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 12137951, 12644484; Product type e : enzyme NP_390034.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951 NP_390035.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin NP_390036.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390037.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme NP_390038.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390039.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390040.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390041.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390042.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390043.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390044.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type h: extrachromosomal origin NP_390045.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390046.1 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_390047.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10376821 NP_390048.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821 NP_390049.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821, 401505; Product type pe: enzyme NP_390051.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress NP_390052.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_390053.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809700, 9571784; Product type pr: regulator NP_390054.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11583854, 15849754, 16850406; Product type t : transporter NP_390055.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390056.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390057.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390058.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680962, 14766920, 16305244, 19027886, 10837475; Product type f: factor NP_390059.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15060025 NP_390060.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic NP_390061.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399512, 16585774; Product type r: regulator NP_390062.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16585774, 16850406; Product type pe: enzyme NP_390063.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390064.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10574451, 12682299, 2840350, 3918568; Product type e: enzyme NP_390065.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_390066.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8534098; Product type pe : enzyme NP_390067.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390068.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390069.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390070.2 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_390071.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390072.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390073.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871, 14617062; Product type pe: enzyme NP_390074.2 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis NP_390075.1 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids NP_390076.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840, 9920884; Product type f: factor NP_390077.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16625836; Product type f: factor NP_390078.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390079.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390080.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390081.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390082.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9888800 YP_054584.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type cp: cell process NP_390083.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16045613, 17038322, 17905985; Product type e: enzyme YP_003097753.1 Evidence 5: No homology to any previously reported sequences NP_390084.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390085.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390086.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406, 7726551, 8396117; Product type pe: enzyme NP_390087.1 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_390088.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923093, 15549109, 15849754, 16850406; Product type t: transporter NP_390089.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine NP_390090.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7765282; Product type e: enzyme NP_390091.1 transports degraded pectin products into the bacterial cell NP_390092.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 9846747; Product type e: enzyme NP_390093.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 15039578, 9846747; Product type e : enzyme NP_390094.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311, 17322190, 9846747; Product type r: regulator NP_390095.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate NP_390096.1 Involved in the metabolism of 2-deoxyglucose NP_390097.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8385320; Product type pe : enzyme NP_390098.1 Evidence 5: No homology to any previously reported sequences YP_003097754.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390099.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390100.1 GpsB; guiding PBP1 shuttling; similar to DivIVA NP_390101.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390102.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10075739, 10400595, 1518043, 1691789, 2821284; Product type cp: cell process NP_390103.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390104.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390105.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10627040; Product type pe : enzyme NP_390106.1 Evidence 5: No homology to any previously reported sequences NP_390107.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390108.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_390109.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390110.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15687200 YP_054585.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362; Product type cp: cell process NP_390111.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390112.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC NP_390113.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10322023, 10692371, 12562814, 15262952; Product type e: enzyme NP_390114.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390115.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11160880, 12682299, 9808040; Product type e : enzyme NP_390116.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15556628, 15686560, 16002087, 16677303, 16855238, 17277452, 18206906; Product type f : factor NP_390117.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_390118.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_390119.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390120.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390121.1 unwinds DNA NP_390122.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_390123.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_390124.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_390125.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12368242, 15459338; Product type e: enzyme NP_390126.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity NP_390127.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751541; Product type pe : enzyme NP_390128.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11004195 NP_390129.1 catalyzes the formation of methylglyoxal from glycerone phosphate NP_390130.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_390131.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16390452; Product type e: enzyme NP_390132.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390133.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922; Product type m: membrane component NP_390134.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390135.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme NP_390136.1 electron transport protein NP_390137.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme NP_390138.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390139.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875 NP_390140.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390141.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_390142.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_390143.2 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_390144.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_390145.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_390146.3 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis NP_390147.3 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water NP_390148.2 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_390149.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_390150.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10818343, 15865424, 16060652, 2105742, 8378335, 9384560; Product type e : enzyme NP_390151.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_390152.3 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_390153.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 15544802, 7635819, 7893679, 8244966; Product type e: enzyme NP_390154.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_390155.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme NP_390156.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_390157.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme NP_390158.1 tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination NP_390159.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_390160.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10224127, 10231583, 10715001, 11931565, 1382620, 9106208; Product type f : factor NP_390161.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160095, 17114257, 17427285; Product type cp: cell process NP_390162.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390163.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390164.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_390165.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_003097755.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390166.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390167.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_003097756.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390168.3 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate NP_390169.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_390170.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_390171.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390172.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16249258; Product type pr : regulator NP_390173.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332; Product type cp: cell process NP_390174.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332, 16905870, 16907803; Product type cp: cell process NP_390175.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16816000, 16850406, 17020587; Product type e: enzyme NP_390176.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390177.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18326565, 9829940; Product type e: enzyme NP_390178.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence NP_390179.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme NP_390180.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390181.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244 NP_390182.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_390183.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16385024; Product type e: enzyme NP_390184.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390185.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12538057; Product type c: carrier NP_390186.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 15849754, 16850406, 17693491; Product type t: transporter NP_390187.1 Evidence 5: No homology to any previously reported sequences NP_390188.2 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_390189.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis NP_390190.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10712692, 14762009, 9393439; Product type r: regulator NP_390191.2 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance NP_390192.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11222591, 14996800, 16825793, 16885456, 17189364, 17322317; Product type rc : receptor NP_390193.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 15375128, 16825793, 16885456, 17322317; Product type r : regulator NP_390194.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 15849754, 16850406; Product type f: factor NP_390195.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 16825793, 9395519; Product type f: factor NP_390196.2 catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c NP_390197.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9888802; Product type e : enzyme NP_390198.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process NP_390199.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process NP_390200.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498740, 7642500, 8892816, 9864321; Product type cp: cell process NP_390201.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423 NP_390202.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137; Product type f: factor NP_390203.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB NP_390204.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390205.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466513; Product type pe : enzyme NP_390206.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_390207.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_390208.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_390209.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 18986985, 9068650; Product type e: enzyme NP_390211.1 Evidence 5: No homology to any previously reported sequences NP_390212.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15502345, 11004175, 10982814, 9694797, 9823656, 10198007, 10336490; Product type e: enzyme NP_390213.1 Evidence 5: No homology to any previously reported sequences YP_003097757.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390215.1 Evidence 5: No homology to any previously reported sequences NP_390216.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390217.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8639516, 9063446, 9748346; Product type e: enzyme NP_390218.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17434969; Product type pf : factor NP_390219.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14627808, 9044297; Product type e: enzyme NP_390220.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process YP_003097758.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113, 17573930; Product type cp: cell process YP_003097759.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17573930; Product type cp: cell process NP_390222.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process NP_390223.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process NP_390224.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process NP_390225.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3114420; Product type cp: cell process NP_390226.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. NP_390227.1 binds to sigma F preventing its association with RNA polymerase during sporulation NP_390228.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11173484, 15819616, 16824103; Product type cp: cell process NP_390229.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8021191, 8936302, 9864321; Product type cp: cell process NP_390230.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_390231.2 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose NP_390232.2 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003097760.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390233.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12374814, 14563870, 15802251, 16672620; Product type r: regulator NP_390234.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17376078; Product type cp: cell process NP_390235.1 Evidence 5: No homology to any previously reported sequences NP_390236.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme NP_390237.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10903309, 15849754, 16850406; Product type t: transporter NP_390238.2 catalyzes the formation of fumarate from aspartate NP_390239.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 1711029; Product type e: enzyme NP_390240.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346; Product type r: regulator NP_390241.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390242.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10542272, 17693564; Product type e: enzyme NP_390243.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15317791, 16242712, 9643546; Product type e: enzyme NP_390244.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390245.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390246.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390247.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390248.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390249.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme NP_390250.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme NP_390251.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951, 16267290 NP_390252.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_390253.1 Evidence 5: No homology to any previously reported sequences NP_390254.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527, 15849754, 16850406; Product type pt: transporter NP_390255.1 Evidence 5: No homology to any previously reported sequences NP_390256.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390257.2 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_390258.2 catalyzes the formation of pyruvate from serine NP_390259.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390260.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390261.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme NP_390262.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390263.1 catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds NP_390264.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme NP_390265.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions NP_390266.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_390267.2 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_390268.2 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_054586.1 Evidence 5: No homology to any previously reported sequences NP_390269.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site NP_390270.3 Evidence 4: Homologs of previously reported genes of unknown function NP_390271.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390272.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390273.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390274.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390275.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390276.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter NP_390277.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15849754, 16850406; Product type t: transporter NP_390278.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter NP_390279.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390280.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 7961792, 8098708; Product type pe: enzyme NP_390281.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10961951, 11321573, 15849754, 16850406; Product type t : transporter NP_390282.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11201751, 11839496, 12682015, 14985361; Product type r: regulator NP_390283.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme NP_390284.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme NP_390285.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme NP_390286.2 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_390287.2 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate NP_390288.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme NP_390289.2 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate NP_390290.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682, 16585774; Product type r: regulator NP_390291.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390292.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12706720; Product type e: enzyme NP_390293.2 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C NP_390294.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration NP_390295.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme NP_390296.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8759838; Product type e: enzyme NP_390297.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_390298.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390299.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390300.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390301.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390302.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12406209, 15556029, 15808745, 8504245; Product type r: regulator NP_390303.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12218026, 15292188, 16164552, 16238631, 16818230; Product type cp: cell process NP_390304.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15186413, 15849320, 16061691, 16385024; Product type f: factor NP_390305.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_390306.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390307.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_390308.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17147392, 8755734; Product type e : enzyme NP_390309.2 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_390310.2 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_390311.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_390312.2 Regulates rRNA biosynthesis by transcriptional antitermination NP_390313.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254 NP_390314.2 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_390315.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_390316.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15752199, 16959571, 1766372; Product type cp: cell process NP_390317.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process NP_390318.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process NP_390319.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process NP_390320.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process NP_390321.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process NP_390322.1 necessary for complete engulfment of forespore NP_390323.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process NP_390324.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390325.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_390326.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390327.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_390328.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390329.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390330.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390331.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390332.2 involved in manganese homeostasis; activates the transcription of the mntABCD operon NP_390333.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390334.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11092948; Product type pe : enzyme NP_390335.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein NP_390336.2 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein NP_390337.2 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein NP_390338.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390339.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390340.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10547280, 11751836, 15661000, 15805512, 8549812; Product type r: regulator NP_390341.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15805512, 16585769, 16740951, 16923912; Product type r: regulator NP_390342.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10827084, 16430695, 16430696, 18047568; Product type cp: cell process NP_390343.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 10827084, 15101989, 16430695; Product type e: enzyme NP_390344.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 14707086, 16430695, 17554552; Product type lp : lipoprotein NP_390345.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_390346.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390347.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process NP_390348.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process NP_390349.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 7783624, 9224890, 9422590, 9723928; Product type cp: cell process NP_390350.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 9224890, 9422590, 9723928; Product type cp: cell process NP_390351.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 16751195, 7783624, 9723928; Product type cp: cell process NP_390352.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process NP_390353.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11298275, 15528548, 16009134, 9723928; Product type cp: cell process NP_390354.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15856219; Product type pt : transporter NP_390355.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_390356.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor NP_390357.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18643936; Product type r: regulator NP_390358.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390359.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390360.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390361.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390362.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390363.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12765833; Product type pe : enzyme NP_390364.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme NP_390365.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15018644, 15050034, 9620975; Product type e: enzyme NP_390366.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15050034 NP_390367.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15050034, 16355228; Product type e: enzyme NP_390368.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390369.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17329806; Product type e: enzyme NP_570908.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_390370.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390371.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390372.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390373.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390374.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_390375.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_390376.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter NP_390377.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter NP_390378.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 15289558, 9098050, 9593301; Product type t: transporter NP_390379.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990, 9139922, 9851991; Product type e: enzyme NP_390380.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pt: transporter NP_390381.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074093, 15897454, 18084079, 9393707, 9573176, 9658017; Product type e : enzyme NP_390382.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390383.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype NP_390384.2 Evidence 5: No homology to any previously reported sequences NP_390385.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype NP_390386.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_390387.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390388.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390389.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12180919, 12426338, 12904577, 17216355; Product type r: regulator NP_390390.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390391.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390392.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues NP_390393.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871, 16352840, 18203828; Product type e: enzyme NP_390394.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390395.2 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_390396.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390397.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18420655; Product type e: enzyme NP_390398.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10024472, 10473570, 11361075, 15995641; Product type c: carrier NP_390399.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium NP_390400.2 synthesizes RNA primers at the replication forks YP_054587.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 9864351 NP_390401.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9387153 NP_390402.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator NP_390403.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator NP_390404.2 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_390405.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_390406.2 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_003097761.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390407.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_390408.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217788, 2526291, 8157589; Product type e: enzyme NP_390409.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923107, 17535816; Product type e: enzyme NP_390410.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390411.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751502; Product type pe : enzyme NP_390412.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12762842; Product type ph: phenotype NP_390413.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14523133; Product type cp: cell process NP_390414.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922 NP_390415.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390416.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12501411; Product type cp : cell process NP_390417.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390418.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390419.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_390420.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390421.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572129, 15339930, 18252828, 8844851; Product type e: enzyme NP_390422.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_390423.2 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_390424.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_390425.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_390426.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_390427.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_390428.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_390429.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_390430.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390431.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17376078; Product type cp: cell process NP_390432.1 Initiates the rapid degradation of small acid-soluble proteins during spore germination NP_390433.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_390434.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_003097762.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390435.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12123453, 15661011, 16751195; Product type cp: cell process NP_390436.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7768800; Product type cp : cell process NP_390437.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195; Product type cp: cell process NP_390438.1 may be involved in regulation of competence genes NP_390439.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390440.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390441.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311; Product type pe : enzyme NP_390442.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_390443.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 17005971, 17105995; Product type pf: factor NP_390444.2 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_390445.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis NP_390446.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_054588.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15023339, 16796683, 19040634; Product type f: factor NP_390447.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390448.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10974124, 15687192; Product type e: enzyme NP_390449.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 15855514, 16850406 NP_390450.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate NP_390451.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390452.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17209033, 7746143; Product type e: enzyme NP_390454.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1631085, 2163341, 7704261, 8300549, 8969508; Product type e: enzyme NP_390455.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates NP_390456.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 16905151, 9537360; Product type t: transporter NP_390457.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16905151, 8760915, 8969508, 9537360; Product type pe: enzyme NP_390458.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537360; Product type r : regulator NP_390459.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8760915, 8969508; Product type h : extrachromosomal origin NP_390460.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10629174, 11679073, 12897006, 8760915, 8969508; Product type r: regulator NP_390461.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174; Product type r: regulator NP_390462.1 Evidence 5: No homology to any previously reported sequences NP_390463.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390464.1 Evidence 5: No homology to any previously reported sequences NP_390465.1 Evidence 5: No homology to any previously reported sequences NP_390466.1 Evidence 5: No homology to any previously reported sequences NP_390467.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1683402, 2127796; Product type e: enzyme NP_390468.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390469.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390470.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390471.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390472.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508 NP_390473.1 Evidence 5: No homology to any previously reported sequences NP_390474.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508 NP_390475.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_390476.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390477.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390478.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390479.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390480.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8760915, 8969508; Product type pe: enzyme NP_390482.1 Evidence 5: No homology to any previously reported sequences NP_390483.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508 NP_390485.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097763.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390486.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390487.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390488.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390489.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390490.1 Evidence 5: No homology to any previously reported sequences NP_390491.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_390492.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390493.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390494.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_390495.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_390496.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390497.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390498.1 Evidence 5: No homology to any previously reported sequences NP_390499.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390500.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390501.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390502.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_003097764.1 Evidence 5: No homology to any previously reported sequences NP_390503.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390504.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_390505.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390506.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390507.1 Evidence 5: No homology to any previously reported sequences NP_390508.1 Evidence 5: No homology to any previously reported sequences NP_390509.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390510.1 Evidence 5: No homology to any previously reported sequences NP_390511.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390512.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390513.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390514.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390515.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390517.1 Evidence 5: No homology to any previously reported sequences NP_390518.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12897016, 15849754, 16850406; Product type m : membrane component NP_390519.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_390520.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 18175906; Product type r: regulator NP_390521.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390522.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390524.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053405; Product type pe : enzyme NP_390525.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390526.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390527.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390528.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390530.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390531.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390532.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390533.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme NP_390534.1 Evidence 5: No homology to any previously reported sequences NP_390535.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 7608059, 9083003; Product type r: regulator NP_390536.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 15849754, 16850406, 9083003; Product type t : transporter NP_390537.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 9083003; Product type e: enzyme NP_390538.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure YP_003097765.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390539.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390540.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390541.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12100555, 12527699, 9099864; Product type pe: enzyme NP_390542.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 12100555, 15849754, 15948947, 16850406; Product type t : transporter NP_390543.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390544.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9023181; Product type r : regulator NP_390545.2 Evidence 6: Doubtful CDS NP_390546.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8544834, 9287000, 9531631; Product type t: transporter NP_390547.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type pt: transporter NP_390548.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 9287000; Product type t: transporter NP_390549.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type r : regulator NP_390550.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_390551.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 9778370; Product type e: enzyme NP_390553.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390554.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390555.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390556.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8293959; Product type e : enzyme NP_390557.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9501443; Product type pe : enzyme NP_390558.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15347750; Product type e: enzyme NP_390559.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390560.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390561.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription NP_390562.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390563.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053381, 15849754, 16850406; Product type pt: transporter NP_390564.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390565.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390566.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065371, 11320136, 1664582; Product type e: enzyme NP_390567.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390568.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390569.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390570.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390571.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390572.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process NP_390573.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process NP_390574.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7926692; Product type pe : enzyme NP_390575.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390576.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process NP_390578.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator NP_390579.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390580.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12775685, 17257049, 17933887; Product type f: factor NP_390581.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7646030, 8057358; Product type e: enzyme NP_390582.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter NP_390583.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter NP_390584.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589728, 9033408, 9622354; Product type t: transporter NP_390585.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2117666, 9033408; Product type t: transporter NP_390586.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1619665, 1900939, 7592487, 8057358, 9622354; Product type r: regulator NP_390587.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter NP_390588.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390589.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390590.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator NP_390591.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator NP_390592.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15661003; Product type e: enzyme NP_390593.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390594.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type e: enzyme NP_390595.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type r: regulator NP_390596.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pe : enzyme NP_390597.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390598.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390599.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390600.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913079; Product type pe : enzyme NP_390601.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079 NP_390602.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751 NP_390603.1 catalyzes the formation of L-homocysteine from cystathionine NP_390604.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751; Product type e: enzyme NP_390605.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine NP_390606.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 17056751; Product type pe: enzyme NP_390607.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390608.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14679248 NP_390609.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679248; Product type e: enzyme NP_390610.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_390611.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor NP_390612.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390613.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390614.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390615.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390616.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390617.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_054589.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390618.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_390619.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390620.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type t: transporter NP_390621.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type lp: lipoprotein NP_390622.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter NP_390623.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter YP_003097766.1 Evidence 4: Homologs of previously reported genes of unknown function YP_003097767.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390624.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390625.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557815, 3537961; Product type pe: enzyme NP_390626.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11777911, 12594026; Product type pf: factor NP_390627.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_390629.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 10930739, 12682299, 17064282, 7496536; Product type e: enzyme NP_390630.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668000, 16109943, 16513748, 17056751, 18974048; Product type r: regulator NP_390631.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390632.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177353; Product type pe : enzyme NP_390633.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_390634.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_390635.1 Evidence 5: No homology to any previously reported sequences NP_390636.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390637.2 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_390638.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11545276, 12081964, 13129942, 15066282, 6248722; Product type e: enzyme NP_390639.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_390640.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390641.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390642.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter NP_390643.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_390644.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 19028902; Product type r: regulator NP_390645.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15292147, 15849754, 16850406, 1744050; Product type pt: transporter NP_390646.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390647.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390648.2 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex NP_390649.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) NP_390650.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_003097768.1 Evidence 4: Homologs of previously reported genes of unknown function YP_054590.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_390652.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_390653.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931291, 16049010; Product type f: factor NP_390654.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9099855; Product type pt: transporter NP_390655.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390656.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390658.1 Evidence 5: No homology to any previously reported sequences YP_003097769.1 Evidence 5: No homology to any previously reported sequences NP_390659.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1400476, 15849754, 16850406; Product type t : transporter NP_390660.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390661.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9770294; Product type f: factor NP_390662.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438771, 10714986, 11040425, 15901704; Product type f: factor NP_390663.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_390664.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_390665.1 catalyzes the formation of oxaloacetate from L-aspartate NP_390666.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis NP_390667.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16199587, 18276644; Product type r: regulator NP_390668.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis NP_390669.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 2537815 NP_390670.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_390671.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10997904, 9443976, 9477965, 9726997, 9809070; Product type e: enzyme NP_390672.1 involved in the peptidyltransferase reaction during translation NP_390673.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11567142 NP_390674.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299; Product type f: factor NP_390675.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type cp : cell process NP_390676.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type r : regulator NP_390677.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11886553, 12426398, 12492852, 12492861, 16322744, 16885474, 17513368; Product type cp: cell process NP_390678.1 blocks the formation of polar Z-ring septums NP_390679.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16101995, 16850406; Product type s: structure NP_390680.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_390681.2 functions in MreBCD complex in some organisms NP_390682.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase NP_390683.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_390684.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16959571, 17376078; Product type cp: cell process NP_390685.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16751195, 16850406, 2553669, 9723928; Product type cp: cell process NP_390686.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2105929, 2985605, 3040739, 6994831, 9098041; Product type e: enzyme NP_390687.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_003097770.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390688.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16371471, 16390444; Product type cp: cell process NP_390689.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11325931, 16371471, 16950916; Product type cp: cell process NP_390690.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_390691.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_390692.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 15802251, 2110138; Product type e: enzyme NP_390693.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_390694.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12029044, 15802251, 15849754, 16850406, 8012594; Product type f: factor NP_390695.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_390696.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390697.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_390698.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926, 15987505; Product type e: enzyme NP_390699.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926; Product type e: enzyme NP_390700.2 binds and unfolds substrates as part of the ClpXP protease NP_390701.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_390702.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390703.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_390704.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_390705.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_390706.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis NP_390707.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_390708.2 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_390709.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit NP_390710.1 Evidence 5: No homology to any previously reported sequences NP_390711.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390712.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type ph : phenotype NP_390713.2 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme NP_390714.1 hydrolyzes non-standard nucleotides such as xanthine and inosine NP_390715.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_390716.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14662349; Product type cp: cell process NP_390717.2 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_390718.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390719.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11243786, 11418558, 11741866, 14702409, 17172339; Product type cp: cell process NP_390720.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390721.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase NP_390722.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_390723.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11803018, 15849754, 16850406, 1707123; Product type e: enzyme NP_390724.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390725.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_390727.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_390728.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15937154; Product type c: carrier NP_390729.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 14973026; Product type e: enzyme NP_390730.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme NP_390731.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10026281, 17189250; Product type e: enzyme NP_390732.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_390733.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type r: regulator NP_390734.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme NP_390735.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390736.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange NP_390737.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18938175; Product type e: enzyme NP_390738.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390739.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390740.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_390741.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_390742.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_390743.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390744.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362, 8171126; Product type f: factor NP_390745.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390746.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8606183; Product type e: enzyme NP_390747.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme NP_390748.1 Evidence 5: No homology to any previously reported sequences NP_390749.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1848300; Product type ph : phenotype NP_390750.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 12777810, 14973026, 16233670; Product type e: enzyme NP_390751.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter NP_390752.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter NP_390753.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026; Product type lp : lipoprotein NP_390754.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme NP_390755.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme NP_390756.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source NP_390757.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate NP_390758.2 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism NP_390759.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14973026; Product type e: enzyme NP_390760.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390761.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10960106 NP_390762.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_390763.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_390764.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17289755, 8722036; Product type s : structure NP_390765.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_390767.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type lp : lipoprotein NP_390768.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases NP_390769.1 negatively regulates murein hydrolase activity NP_390770.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12034833, 12914674; Product type r: regulator NP_390771.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12914674; Product type rc : receptor NP_390772.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390773.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_390774.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390775.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390776.1 Primosomal protein that may act to load helicase DnaC during DNA replication NP_390777.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15186423, 16002087, 17289076; Product type f: factor NP_390778.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16950922; Product type r: regulator NP_390779.2 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine NP_390780.1 NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis NP_390781.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390782.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390783.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390784.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_390785.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390786.2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_390787.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_390788.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10433720, 12486063, 14762014, 15205429, 16452408, 17085571; Product type rc : receptor NP_390789.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762014, 14973033, 15205429, 16030210, 16452408, 16816204; Product type r: regulator NP_390790.1 Catalyzes the reversible oxidation of malate to oxaloacetate NP_390791.1 Converts isocitrate to alpha ketoglutarate NP_390792.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate NP_390793.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390794.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type pt: transporter NP_390795.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein NP_390796.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_390797.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_390798.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_390799.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_390800.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme NP_390801.1 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_003097771.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype NP_390802.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype YP_003097772.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390803.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17586819; Product type e: enzyme NP_390804.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390805.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390806.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390807.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10588044, 10939241, 11423008, 16109943; Product type pe: enzyme NP_390808.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15668000, 16109943, 17590224; Product type e: enzyme NP_390809.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme NP_390810.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme NP_390811.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme NP_390812.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter NP_390813.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter NP_390814.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter NP_390815.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter NP_390816.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter NP_390817.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 11423008, 16109943; Product type pe: enzyme NP_390818.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 11423008, 16109943, 16513748; Product type r: regulator NP_390819.2 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins NP_390820.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_390821.2 Evidence 5: No homology to any previously reported sequences; PubMedId: 11423008 NP_390822.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_390823.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_390824.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15269205; Product type f: factor NP_390825.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_390826.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390827.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_390828.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390829.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390830.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390831.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 16484219, 9987136; Product type e: enzyme NP_390832.1 catalyzes the phosphorylation of NAD to NADP NP_390833.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390834.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390835.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 2456528, 2468649, 3009398; Product type cp: cell process NP_390836.2 Required for the synthesis of the thiazole moiety NP_390837.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 11443125, 13129955, 14757766, 16388576, 17237162; Product type e: enzyme NP_390838.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11528000, 15849754, 16850406; Product type t : transporter NP_390839.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation NP_390840.1 catalyzes the formation of L-histidinol from L-histidinol phosphate NP_390841.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pr : regulator NP_390842.2 Evidence 4: Homologs of previously reported genes of unknown function NP_390843.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390844.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_390845.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_003097773.1 Evidence 5: No homology to any previously reported sequences NP_390846.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA NP_390847.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 18487328, 7934817; Product type e : enzyme NP_390848.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type f: factor NP_390849.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type e: enzyme NP_390850.1 Homolog of MotB, appears to be involved in motility on surfaces or under specific ionic conditions. With MotP (a Mot A homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. NP_390851.1 Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. NP_390852.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11931564, 14665673, 16316990, 17085448; Product type r: regulator NP_390853.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate NP_390854.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232 NP_390855.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232 NP_390856.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232 NP_390857.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_390859.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11134515, 11208805, 3129532; Product type pe: enzyme NP_390860.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_390861.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520 NP_390862.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12719520, 15937154; Product type pe: enzyme NP_390863.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390864.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8535515; Product type e: enzyme NP_390865.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390866.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_390867.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390868.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_390869.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390870.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11545674, 9026440; Product type pe: enzyme NP_390871.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16582490, 9453151; Product type e: enzyme NP_390872.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390873.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390874.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17012785; Product type s: structure NP_390875.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16267287; Product type pe: enzyme NP_390876.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases NP_390877.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 15849754, 16850406; Product type t: transporter NP_390878.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390879.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_390880.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618461; Product type pr : regulator NP_390882.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390883.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11254558, 15044829, 15849754, 16850406; Product type pe: enzyme NP_390884.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390885.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14996799, 15849754, 16850406, 8752321, 9925583; Product type t: transporter NP_390886.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8990290 NP_390887.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pe: enzyme NP_390888.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type pe : enzyme NP_390889.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type lp : lipoprotein NP_390890.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15148314, 15906318, 16781735, 16870154, 17449691; Product type e: enzyme NP_390892.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390893.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_390894.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390895.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390896.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390897.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11368323; Product type e: enzyme NP_390898.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine NP_390899.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_390900.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717296, 12368242, 8763940; Product type e: enzyme NP_390901.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_390902.3 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A NP_390903.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390904.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288; Product type r: regulator NP_390905.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 16707683; Product type lp : lipoprotein NP_390906.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 1537846, 15849754, 16707683, 16850406; Product type t: transporter NP_390907.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1537846, 15849754, 16707683, 16850406; Product type t: transporter NP_390908.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12847288; Product type e: enzyme NP_390909.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme NP_390910.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_390911.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16923906; Product type pm : membrane component NP_390912.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11964249, 16923906, 16923909, 17200735, 17443319, 17575448; Product type rc : receptor NP_390913.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534, 15849754, 16850406; Product type pt: transporter NP_390914.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818 NP_390915.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 15849754, 16850406, 17905982; Product type t: transporter NP_390916.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 17905982; Product type t: transporter NP_390917.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type rc: receptor NP_390918.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type r: regulator NP_390919.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter NP_390920.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter NP_390921.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter NP_390922.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter NP_390923.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter NP_390924.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 11756427, 17194626; Product type r: regulator NP_390925.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390926.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390927.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme NP_390928.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390929.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11796336; Product type e: enzyme NP_390930.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390931.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10498721, 15849754, 16850406; Product type pt: transporter NP_390932.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme NP_390933.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_390934.2 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP NP_390935.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390936.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390937.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_390939.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_390940.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390941.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576788, 16513759; Product type e: enzyme NP_390942.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type h: extrachromosomal origin NP_390943.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12767829, 16091047, 16861227, 16935006; Product type e: enzyme YP_003097774.1 Evidence 5: No homology to any previously reported sequences NP_390944.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_390945.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 NP_390946.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390947.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12193617; Product type e: enzyme NP_390948.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_390949.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17114254, 9852001; Product type pe: enzyme NP_390950.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11073895, 15576792, 15849754, 16850406; Product type pe: enzyme YP_003097775.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390952.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16566604, 16704341, 16850406; Product type t : transporter NP_390953.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16704341, 16850406; Product type t: transporter NP_390954.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type t: transporter NP_390955.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type lp: lipoprotein NP_390956.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 6780514, 8566759, 9139683; Product type e: enzyme NP_390957.1 converts O-succinylbenzoate to O-succinylbenzoyl-CoA NP_390958.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_390959.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12454479; Product type pe : enzyme NP_390960.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis NP_390961.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 6780514, 8169214, 8566759; Product type e: enzyme NP_390962.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987 NP_390963.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390964.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390965.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390966.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390967.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390968.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 7545510, 9603889; Product type cp: cell process NP_390969.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 9603889; Product type cp: cell process NP_390970.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor NP_390971.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type prc: receptor NP_390972.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15272305, 8145641; Product type e: enzyme NP_390973.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose NP_390974.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8145641, 9244254; Product type e: enzyme NP_390975.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_390976.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_390977.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter NP_390978.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_390979.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 17482313, 9153235, 9987136; Product type pf: factor NP_390980.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 15849754, 16850406, 18696230; Product type pm: membrane component NP_390981.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390982.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11886751 NP_390983.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8752328; Product type e: enzyme NP_390984.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8752328, 9297465; Product type e: enzyme NP_390985.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8752328; Product type pr : regulator NP_390986.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390987.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter NP_390988.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406, 17932047; Product type t : transporter NP_390989.1 Evidence 4: Homologs of previously reported genes of unknown function NP_390990.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12525152, 16855244; Product type e: enzyme NP_390991.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_390992.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 15699190, 16855246; Product type e: enzyme NP_390993.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell NP_390994.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_390995.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12450853; Product type ph: phenotype NP_390996.1 catalyzes the formation of L-rhamnulose from L-rhamnose NP_390997.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15876375; Product type e: enzyme NP_390998.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16674975; Product type e: enzyme NP_390999.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11496004; Product type pr : regulator NP_391000.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391001.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor NP_391002.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 8188684, 9721285; Product type rc : receptor NP_391003.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor NP_391004.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 14731274, 15317802, 15544802; Product type rc: receptor NP_391005.1 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links YP_003097776.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391006.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391007.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1761534; Product type pe : enzyme NP_391008.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391009.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16704729, 16850406; Product type pe: enzyme YP_003097777.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16704729; Product type f : factor YP_003097778.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15731457; Product type m: membrane component NP_391010.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16704729; Product type pt : transporter NP_391011.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391012.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391013.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_391014.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391015.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317791, 9643546; Product type pe: enzyme NP_391016.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391017.1 induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation NP_391018.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12670965; Product type pe : enzyme NP_391019.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391020.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391021.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391022.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15760717; Product type e: enzyme NP_391023.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 11069677, 15849754, 16850406, 9426145; Product type e: enzyme NP_391024.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9426145; Product type f : factor NP_391025.1 inhibitor of the KinA pathway of sporulation NP_391026.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391027.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7961491, 9274030; Product type e: enzyme NP_391028.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391029.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391030.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration NP_391031.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12949159; Product type r: regulator NP_391032.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_391033.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391034.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391035.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391036.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11004162, 12949159, 15849754, 16850406; Product type t: transporter NP_391037.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor NP_391038.2 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_391039.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport NP_391040.2 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_391041.3 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_054591.2 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_391043.2 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_391044.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport NP_391045.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391046.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972833, 11179649, 11717295, 12950917, 16816200; Product type r: regulator NP_391047.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10419951, 14679219, 15066026, 16091050, 16787201, 7698645, 7855425; Product type rc: receptor NP_391048.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141, 18323630; Product type f : factor NP_391049.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141; Product type e: enzyme NP_391050.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16251307, 16942812, 1901055; Product type r: regulator NP_391051.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 16321932; Product type cp: cell process NP_391052.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17153922; Product type pe : enzyme NP_391053.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_391054.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15135535, 17382284; Product type e: enzyme NP_391055.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391056.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391057.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391058.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pm: membrane component NP_391059.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391060.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391061.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391062.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11745140; Product type pe : enzyme NP_391063.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 15576783 NP_391064.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576783; Product type ph: phenotype NP_391066.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor NP_391067.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pe: enzyme NP_391068.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pf: factor NP_391069.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783 NP_391070.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391071.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226620; Product type e : enzyme NP_391073.2 Evidence 4: Homologs of previously reported genes of unknown function YP_003097779.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11112781 NP_391076.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11112781, 12354229, 16672620; Product type e: enzyme NP_391077.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme NP_391078.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme NP_391079.2 synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis NP_391080.2 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin NP_391081.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16889643; Product type e: enzyme NP_391082.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11598126, 16341843; Product type pe: enzyme NP_391083.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11717296, 15849754, 16850406; Product type pt: transporter NP_391084.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15135544, 15849754, 16850406; Product type t: transporter NP_391085.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_391086.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391087.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391088.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391089.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391090.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154, 17015645; Product type pe: enzyme NP_391091.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme NP_391092.1 Evidence 5: No homology to any previously reported sequences NP_391093.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11591660, 6408059; Product type e: enzyme NP_391094.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16210326; Product type pe : enzyme NP_391095.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16210326, 17588214; Product type e: enzyme NP_391096.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391097.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_391098.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391099.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391100.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17015645; Product type pe : enzyme NP_391101.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11551182; Product type pe : enzyme NP_391102.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17237162; Product type pf : factor NP_391103.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8576092; Product type pe : enzyme NP_391104.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_391105.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_391106.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_391107.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type cp: cell process NP_391108.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391109.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15664928, 16766528; Product type pe: enzyme NP_391110.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391111.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717 NP_391112.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_391113.2 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_391114.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12813075; Product type cp: cell process NP_391115.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922; Product type cp : cell process NP_391116.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391117.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391118.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391119.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391120.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391121.1 Plays a crucial role on both purine and pyrimidine metabolism NP_391122.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 12374841; Product type r: regulator NP_391123.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter NP_391124.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter NP_391125.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme NP_391126.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11344136; Product type s: structure YP_003097780.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391127.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme NP_391128.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme NP_391129.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme NP_391130.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme NP_391131.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type c: carrier NP_391132.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11344136; Product type pe : enzyme NP_391133.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide NP_391134.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12490701, 16291680; Product type e: enzyme NP_391135.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391136.2 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes NP_391137.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14641112, 16153181; Product type e: enzyme NP_391138.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter NP_391139.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter NP_391140.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455; Product type pt : transporter NP_391141.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12618455, 16153181; Product type e: enzyme NP_391142.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391143.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_054592.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type f : factor NP_391144.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018 NP_391145.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10882093; Product type pe : enzyme YP_003097781.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391146.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor NP_391147.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16877383; Product type f : factor NP_391148.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 12876288, 14644425, 15901727; Product type e: enzyme NP_391149.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor NP_391150.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16431905; Product type e : enzyme YP_003097782.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391151.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391152.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter NP_391153.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 15849754, 16850406, 17038623, 10094622; Product type t : transporter NP_391154.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter NP_391155.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391156.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme NP_391157.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12794188; Product type pe : enzyme NP_391158.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391159.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_391160.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391161.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme NP_391162.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_391163.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme YP_003097783.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250 NP_391164.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme YP_003097784.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391165.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391166.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12923086; Product type pr : regulator NP_391167.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391168.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391169.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391170.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391171.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391172.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391173.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter NP_391174.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_391177.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391178.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 8709848; Product type f: factor NP_391180.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11133960, 11717295, 16033468, 16911528; Product type e: enzyme NP_391181.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type r: regulator NP_391182.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type rc: receptor YP_003097785.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391183.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391184.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_003097786.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391185.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process NP_391186.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16740944, 16850406; Product type cp: cell process NP_391187.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process NP_391188.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type r: regulator NP_391189.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type rc: receptor NP_391190.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406, 17660417; Product type m: membrane component NP_391191.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15273097, 16816187 NP_391192.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187; Product type f: factor NP_391193.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406; Product type t: transporter NP_391194.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391195.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 14704351, 17588214; Product type e : enzyme NP_391196.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type pt : transporter NP_391197.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351, 15849754, 16850406; Product type pt: transporter NP_391198.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type t : transporter NP_391199.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9922248; Product type pe : enzyme NP_391200.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391201.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717295, 16306698; Product type rc : receptor NP_391202.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16306698; Product type r: regulator YP_003097787.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18573182, 19047353; Product type r: regulator NP_391203.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 18573182, 19047353; Product type r: regulator YP_003097788.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 18573182, 19047353 NP_391204.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960116, 14697267, 14871895, 17459326, 18573182, 19047353; Product type e : enzyme NP_391205.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391207.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391208.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter NP_391209.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391210.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 8388528, 8596459; Product type t : transporter NP_391211.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 15849754, 16850406, 8388528, 8596459; Product type t: transporter NP_391212.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16850406, 8388528; Product type t: transporter NP_391213.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 8388528; Product type t: transporter NP_391214.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 14627808, 15849754, 16850406; Product type t: transporter YP_054593.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type cp: cell process NP_391215.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_391216.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme NP_391217.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391218.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_391219.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391220.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16232966; Product type e: enzyme NP_391221.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534 NP_391222.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16021482, 16850406; Product type t: transporter NP_391223.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide NP_391224.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11445163, 12169591; Product type e: enzyme NP_391225.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244; Product type e: enzyme NP_391226.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391227.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455116, 11872755, 15661011, 15849754, 16751195, 16850406, 17088376; Product type e: enzyme NP_391228.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 11872755, 12637552, 15661011, 17501922; Product type e: enzyme NP_391229.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8037745, 7721839, 14663075, 12644235, 11934502, 11922674; Product type t: transporter NP_391230.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11922674, 11934502, 12644235, 14663075, 18215122; Product type t: transporter NP_391231.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934502, 12238948, 12590580, 14621987, 14663075, 15212800, 18419582; Product type f: factor NP_391232.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17143269, 18048925; Product type r: regulator NP_391233.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme NP_391234.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds NP_391235.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391236.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391237.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11948170, 15849754, 16850406; Product type pt: transporter NP_391238.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391239.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391240.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_391241.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399495, 15805522, 15983136; Product type e: enzyme NP_391242.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1369099; Product type e: enzyme NP_391243.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074070, 10644701, 16243836; Product type f: factor NP_391244.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391245.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391246.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878, 17227471; Product type r: regulator NP_391247.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391248.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391249.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11872722, 8188684; Product type pr: regulator NP_391250.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter NP_391251.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter NP_391252.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter NP_391253.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter NP_391254.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391255.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16469701, 17069462; Product type f: factor NP_391256.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16469701, 16850406, 17069462; Product type t : transporter NP_391257.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 16469701, 17069462; Product type f: factor NP_391258.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 15849754, 16850406; Product type r: regulator NP_391259.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 17069462; Product type r: regulator NP_391260.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter NP_391261.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter NP_391262.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter NP_391263.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter NP_391264.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391265.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391266.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391267.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391268.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15155184 NP_391269.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391270.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_391271.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate NP_391272.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_391273.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_391274.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10799476, 12123463, 12634343, 17142398, 9588797; Product type e: enzyme NP_391275.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489127, 12622823, 17142398, 17293407, 18052209; Product type r: regulator NP_391276.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9620981; Product type t: transporter NP_391277.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10417639, 11418559, 12949161, 14973026, 16585763; Product type r: regulator NP_391278.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme NP_391279.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391280.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter NP_391281.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391282.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177332; Product type pe : enzyme NP_391283.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391284.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391285.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513748; Product type pe : enzyme NP_391286.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator NP_391287.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_391288.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391289.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391290.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591687, 12620626, 15632289; Product type r: regulator NP_391291.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10632888, 11591687, 15342585, 15632289, 16267279; Product type e: enzyme NP_391292.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178, 17056685; Product type e: enzyme NP_391293.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056685, 9287030; Product type e: enzyme NP_391294.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 17056685; Product type t: transporter NP_391295.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160890, 15849754, 16850406, 17056685; Product type t: transporter NP_391296.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178; Product type t: transporter NP_391297.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10486575, 17056685, 2104611, 9287030; Product type r: regulator NP_391298.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18604637; Product type pr : regulator NP_391299.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391300.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109, 12533460, 12634342, 16166551, 16585774; Product type r: regulator NP_391301.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391302.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme NP_391303.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme NP_391304.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme NP_391305.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme YP_003097789.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pt: transporter NP_391308.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme NP_391309.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15173185, 15661000; Product type pe: enzyme NP_391310.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15083514, 15661000; Product type pe: enzyme NP_391311.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pe: enzyme NP_391312.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme NP_391313.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme NP_391314.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme NP_391315.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme NP_391316.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 15661000, 15741737; Product type e : enzyme NP_391317.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 12970183, 15661000; Product type r : regulator NP_391318.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18430133, 18647168; Product type r: regulator NP_391319.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7828905; Product type e : enzyme NP_391320.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12903944, 17295427, 18326577; Product type e: enzyme NP_391321.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391322.1 Evidence 5: No homology to any previously reported sequences NP_391323.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 2054383, 9987136; Product type e : enzyme NP_391324.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533473, 14679248, 19063962, 7592498, 9987136; Product type e: enzyme NP_391325.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11320136, 11739774, 1400159, 15528654; Product type e: enzyme NP_391326.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11739774, 15528654; Product type e: enzyme NP_391327.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12730183, 15528654, 15849754, 16850406; Product type t: transporter NP_391328.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391329.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_391330.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pm : membrane component NP_391331.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391332.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor NP_391333.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650; Product type f: factor NP_391334.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_391335.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11081794; Product type e: enzyme NP_391336.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10229946, 16707683, 9573215; Product type e: enzyme NP_391337.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type e: enzyme NP_391338.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16707683, 16850406; Product type pt: transporter NP_391339.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter NP_391340.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter NP_391341.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type lp: lipoprotein NP_391342.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825545, 16707683; Product type e: enzyme NP_391343.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pr : regulator NP_391344.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391345.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391346.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391347.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10611359; Product type pe : enzyme NP_391348.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391349.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391350.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12432961; Product type pt : transporter NP_391351.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type rc: receptor NP_391352.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type r: regulator YP_003097790.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_391353.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391354.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559153, 10589728, 1136107, 12972249, 15126459, 16411239, 17142398; Product type r: regulator NP_391355.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10986251, 17603302; Product type pr: regulator NP_391356.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11888293, 16272399; Product type f: factor NP_391357.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391358.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391359.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14597697, 15659166; Product type e: enzyme NP_391360.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 16233686; Product type e: enzyme NP_391361.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391362.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16405427, 18215075; Product type t: transporter NP_391363.1 Evidence 5: No homology to any previously reported sequences NP_391364.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391365.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17590234; Product type lp : lipoprotein NP_391366.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis NP_391367.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_391368.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide NP_391369.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_391370.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_391371.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_391372.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ NP_391373.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine NP_391374.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391375.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658655, 16514142; Product type e: enzyme NP_391376.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391377.1 hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation NP_391378.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391379.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_391380.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system NP_391381.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14557261; Product type e: enzyme NP_391382.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15755726; Product type e: enzyme NP_391383.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16207374; Product type r: regulator NP_391384.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391385.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391386.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391387.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391388.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391389.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391390.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391391.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391392.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391393.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391394.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391395.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16936039; Product type ps : structure NP_391396.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_391397.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_391398.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1744042; Product type pm : membrane component NP_391399.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391400.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391401.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391402.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16030230, 16850406, 18976281, 19019154; Product type cp: cell process NP_391404.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526016, 17557826; Product type e: enzyme NP_391405.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process NP_391406.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process NP_391407.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10473570; Product type f: factor NP_391408.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10473570, 15849754, 16850406; Product type pm: membrane component NP_391409.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1408743, 9696765; Product type f: factor NP_391410.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_391411.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11948165, 16324148, 17274076, 17277072; Product type f: factor YP_003097791.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391412.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16952964; Product type s : structure NP_391413.1 flagellin specific chaperone NP_391414.1 involved in flagellin assembly NP_391415.1 possibly involved in flagella export NP_391416.1 structural flagella protein NP_391417.1 affects carbohydrate metabolism; has regulatory role in many processes NP_391418.1 binds to flagellin and appears to stabilize flagellin during flagella assembly NP_391419.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535 NP_391420.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook NP_391421.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook NP_391422.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_391423.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10207036, 10322161, 14762011, 16673084; Product type r: regulator NP_391424.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696775; Product type pr : regulator NP_391425.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16009133, 8045879, 8412657; Product type pt: transporter NP_391426.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16009133, 8045879, 8412657 NP_391427.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 12123453, 16009133, 8045895; Product type e: enzyme NP_391428.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17114254, 3926750 NP_391429.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897; Product type r: regulator NP_391430.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12183369, 12471443, 12950930, 14563871; Product type rc: receptor NP_391431.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11116084 NP_391432.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391433.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12101296, 12682299, 15849754, 16850406, 17012386, 18156271; Product type e: enzyme NP_391434.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme NP_391435.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme NP_391436.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme NP_391437.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406, 4975313; Product type pe: enzyme NP_391438.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376820, 10913081, 12970183, 16000785; Product type e: enzyme NP_391439.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme NP_391440.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406; Product type pt: transporter NP_391442.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079, 14594841, 17298895, 9537764; Product type e: enzyme NP_391443.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079; Product type r : regulator NP_391444.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974124, 1357079; Product type lp: lipoprotein NP_391445.1 attenuator function for control of operon expression NP_391446.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12107153; Product type e: enzyme NP_391447.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17662947, 2846750, 8126437, 8320212, 9658024; Product type e: enzyme NP_391448.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16735734; Product type e: enzyme NP_391449.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16735734, 7704262; Product type e: enzyme NP_391451.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17012386, 18156271, 7565096; Product type t: transporter NP_391452.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406, 17012386, 18156271, 7565096; Product type t: transporter NP_391453.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386; Product type e: enzyme NP_391454.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386, 2507871, 9457886; Product type e : enzyme NP_391455.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11673441, 12637027, 12637499, 12682299, 16141206, 16689786, 17012386; Product type e: enzyme NP_391456.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 16953575, 17012386; Product type e: enzyme NP_391457.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16141206, 16150696, 16689786, 17012386, 18156271; Product type e: enzyme NP_391458.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16269821, 7952180; Product type pe: enzyme NP_391459.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537764, 10206711; Product type e: enzyme NP_391460.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478, 7581999; Product type e: enzyme NP_391461.2 Evidence 1c: Function experimentally demonstrated in the studied genus; PubMedId: 10411756, 15774895, 3110007, 8012571; Product type rc: receptor NP_391462.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16352818, 16850406; Product type rc: receptor NP_391463.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 16352818; Product type lp: lipoprotein NP_391464.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391465.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391466.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391467.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073126, 12644511; Product type e: enzyme NP_391468.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16267300; Product type f: factor NP_391469.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 12644511; Product type e: enzyme NP_391470.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 15849754, 16689787, 16850406; Product type e: enzyme NP_391471.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11606194, 11751809, 12644511; Product type e : enzyme NP_391472.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16519689; Product type r: regulator NP_391473.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16978644, 7921236; Product type e: enzyme NP_391474.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source NP_391475.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter NP_391476.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7921236; Product type t: transporter NP_391477.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter NP_391478.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15187182 NP_391479.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 11782522 NP_391480.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11782522; Product type e: enzyme NP_391481.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972805, 12363365, 17183216, 7685336; Product type e: enzyme NP_391482.2 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase NP_391483.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 10972805, 12363365, 15978075, 17183216, 7685336; Product type r : regulator NP_391484.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391485.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14762006 NP_391486.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559171, 11737650, 14762006, 8755863; Product type f: factor NP_391487.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762006; Product type f: factor NP_391488.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14762006, 15621419; Product type cp: cell process NP_391489.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391490.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391491.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762019; Product type pe : enzyme NP_391492.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391493.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391494.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391495.1 Evidence 5: No homology to any previously reported sequences NP_391496.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391497.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391498.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1692969; Product type pe : enzyme NP_391499.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391500.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_391501.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391502.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15101989 NP_391503.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391504.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15741737, 15866923, 16415592; Product type e: enzyme NP_391505.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15866923, 16415592, 16549871; Product type e: enzyme NP_391506.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183, 15741737, 16415592, 16549871, 17367396; Product type e: enzyme NP_391507.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183; Product type f: factor YP_003097792.1 Evidence 5: No homology to any previously reported sequences NP_391508.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391509.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391510.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391511.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11491085; Product type r: regulator NP_391512.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762004, 16009133, 16549871; Product type f : factor NP_391513.1 Evidence 5: No homology to any previously reported sequences NP_391514.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391515.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme NP_391516.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16740923; Product type prc : receptor NP_391517.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock NP_391518.2 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_391519.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17227471; Product type r: regulator NP_391520.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure NP_391521.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16621824, 1905667; Product type ps: structure NP_391522.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11290328, 12530960, 14588250, 15745453, 17064365; Product type f: factor NP_391523.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15598884, 9023218, 9324264; Product type r: regulator NP_391524.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9023218; Product type ph : phenotype NP_391525.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391526.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391527.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15266115; Product type pe : enzyme NP_391528.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 15849754, 16850406; Product type t: transporter NP_391529.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391530.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391531.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391532.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 15849754, 16850406, 17001076; Product type t: transporter NP_391533.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 17001076; Product type r: regulator NP_391534.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486040, 14612242, 15838020, 15849754, 15946938, 16850406; Product type e : enzyme NP_391535.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762009, 15849754, 16850406; Product type pm: membrane component NP_391536.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16164552, 16959571, 17121846, 18077456; Product type f: factor NP_391537.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme NP_391538.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391539.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391540.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme NP_391541.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 11581256; Product type r: regulator NP_391542.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391543.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391544.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391545.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_391546.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12401490, 16199586, 9287005; Product type e: enzyme NP_391547.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter NP_391548.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376822, 11988534; Product type f: factor NP_391549.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391550.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 12875849, 9843420; Product type e: enzyme NP_391551.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_391552.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_391553.1 Evidence 5: No homology to any previously reported sequences NP_391554.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391555.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391556.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15752199, 16959571, 17376078; Product type cp: cell process NP_391557.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_391558.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391559.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391560.1 Evidence 5: No homology to any previously reported sequences NP_391561.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_391562.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_391563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_391564.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_391565.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_391566.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_391567.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_391568.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_391569.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12917488, 15849754, 16850406; Product type t: transporter NP_391570.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_391571.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_391572.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210 NP_391573.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_391574.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme NP_391575.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391576.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 16890019, 17005971; Product type pf: factor NP_391577.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391578.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 16824103; Product type e: enzyme NP_391579.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391580.1 Evidence 5: No homology to any previously reported sequences NP_391581.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16364916; Product type e: enzyme NP_391582.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_391583.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391584.1 remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions NP_391585.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12949160, 15849754, 16850406; Product type pt: transporter NP_391586.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_391587.1 catalyzes the formation of thymidine 5'-phosphate from thymidine NP_391588.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_391589.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_391590.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese NP_391591.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_391592.3 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity NP_391593.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis NP_391594.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934609, 16788205, 8257105; Product type r: regulator NP_391595.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391596.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_391597.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling NP_391598.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme NP_391599.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17189250; Product type pe : enzyme NP_391600.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme NP_391601.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8614629; Product type pe : enzyme NP_391602.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391603.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme NP_391604.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12119303, 12354229; Product type pt: transporter NP_391605.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 15743965; Product type e: enzyme NP_391606.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 15849754, 16850406, 7557333, 7860592, 8846791; Product type e : enzyme NP_391607.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme NP_391608.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme NP_391609.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme NP_391610.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 11698370, 16428414; Product type r: regulator NP_391611.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16428414, 16850406; Product type pm: membrane component NP_391612.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16796679, 8682783, 8846791; Product type r: regulator NP_391613.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16796679, 16850406, 8682783, 8846791; Product type t: transporter NP_391614.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_391615.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391616.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12696888, 15743949, 16095584, 17213266; Product type f: factor YP_054594.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pf : factor NP_391617.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066831, 15743949; Product type pe: enzyme NP_391618.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15743949; Product type pm: membrane component NP_391619.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pt: transporter NP_391620.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949, 15849754, 16850406; Product type pm: membrane component NP_391621.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme NP_391622.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme NP_391623.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15849754, 16850406; Product type pm: membrane component NP_391624.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391625.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073041; Product type f: factor NP_391626.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type e: enzyme NP_391627.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type f: factor NP_391628.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391629.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931887, 9723923; Product type e: enzyme NP_391630.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine NP_391631.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10767540, 11567005; Product type cp: cell process NP_391632.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391633.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_391634.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14624569, 14730980, 15301547, 17902707; Product type e: enzyme NP_391635.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391636.2 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins NP_391637.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11104814, 15849754, 16850406; Product type t: transporter NP_391638.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885456; Product type pr : regulator NP_391639.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250 NP_391640.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16855250; Product type pe : enzyme NP_391641.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250 NP_391642.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629188, 16497325; Product type cp: cell process NP_391643.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391644.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391645.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12169591; Product type r: regulator NP_391646.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_391647.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317589, 16403788; Product type pe: enzyme NP_391648.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825; Product type e: enzyme NP_391649.1 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however NP_391650.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023, 15849754, 16850406; Product type t: transporter NP_391651.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15609023, 16030213; Product type e: enzyme NP_391652.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme NP_391653.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 14697267, 15609023, 15628860; Product type e: enzyme NP_391654.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme NP_391655.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15609023, 15849754, 16850406; Product type pt: transporter NP_391656.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7540694, 8113162; Product type t: transporter NP_391657.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8113162; Product type pe : enzyme NP_391658.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate NP_391659.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10468601, 12634342, 15150224, 17183217, 17608797, 18326565; Product type e : enzyme NP_391660.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182; Product type ph: phenotype YP_054595.1 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process NP_391661.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process NP_391662.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391663.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391664.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391665.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391666.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001; Product type pe : enzyme NP_391667.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391668.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14602648; Product type pe : enzyme NP_391669.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391670.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10350455, 11042447, 11733986; Product type e: enzyme NP_391671.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12644503; Product type cp: cell process NP_391672.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391673.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391674.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391675.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391676.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_391677.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391678.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391679.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_003097793.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391681.1 catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine NP_391682.1 Evidence 5: No homology to any previously reported sequences NP_391683.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 3100393; Product type e: enzyme NP_391684.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 15849754, 16850406, 3122206; Product type t: transporter NP_391685.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16207915, 16428414, 16850406; Product type t: transporter NP_391686.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 2163394, 8535520, 8702561; Product type r: regulator NP_391687.2 Evidence 5: No homology to any previously reported sequences NP_391688.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15596354, 16946274, 17666034; Product type e: enzyme NP_391689.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913069, 15774866; Product type pe: enzyme NP_391690.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913069, 15774866, 9535080; Product type e: enzyme NP_391691.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15612918, 15849754, 16850406, 9622350; Product type f: factor NP_391692.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159778; Product type f: factor NP_391693.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme NP_391694.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme NP_391695.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098; Product type e : enzyme NP_391696.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 7495838, 7575098; Product type e: enzyme NP_391697.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391698.2 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism NP_391699.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism NP_391700.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391701.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator YP_003097794.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18647168; Product type r: regulator NP_391702.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_391703.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391704.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391705.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15554971, 16672620, 16987175, 18931290; Product type e: enzyme NP_391706.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 16987175; Product type t: transporter NP_391707.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 16987175; Product type t : transporter NP_391708.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_391709.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP NP_391710.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391711.1 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB NP_391712.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15659658, 15849754, 16850406; Product type r : regulator NP_391713.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391714.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391715.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391716.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391717.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391718.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 8990303; Product type pt: transporter NP_391719.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553828, 17666034, 1938892, 2116590; Product type e: enzyme NP_391720.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 1400159, 15849754, 16850406, 8535520; Product type r: regulator NP_391721.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 12079345, 15528654, 9305644, 9457872; Product type r: regulator NP_391722.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11377871; Product type pe : enzyme NP_391723.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391724.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391725.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_391726.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668014; Product type e: enzyme NP_391727.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17114254, 18067544; Product type e: enzyme NP_391728.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_003097795.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391729.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid NP_391730.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 15849754, 16850406, 17263852; Product type e : enzyme NP_391731.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid NP_391732.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 17263852; Product type pe: enzyme NP_391733.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14665680, 7797557; Product type pe: enzyme NP_391734.2 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_391735.1 Evidence 2b: Function of strongly homologous gene; PubMedId: 8990303; Product type e: enzyme NP_391736.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303; Product type t: transporter NP_391737.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 15849754, 16850406; Product type t: transporter NP_391738.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772; Product type t: transporter NP_391739.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303, 9353933; Product type r: regulator NP_391740.1 Evidence 5: No homology to any previously reported sequences NP_391741.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair NP_391742.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10503549, 9393707, 9555886; Product type e: enzyme NP_391743.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391744.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14769884, 15849754, 16850406; Product type pt: transporter NP_391745.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pt: transporter NP_391746.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator NP_391747.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pr: regulator NP_391748.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator NP_391749.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription NP_391750.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 2191181; Product type pt: transporter NP_391751.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12457846; Product type pe : enzyme NP_391752.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter NP_391753.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter NP_391754.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme NP_391755.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme NP_391756.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566984, 15849754, 16850406; Product type t: transporter NP_391757.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pe : enzyme NP_391758.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor NP_391759.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391760.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter NP_391761.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pr : regulator NP_391762.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme NP_391763.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624, 15849754, 16850406; Product type t : transporter NP_391764.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818, 15033535 NP_391765.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14597172, 9555917; Product type e: enzyme NP_391766.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_391767.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12169591; Product type pr : regulator NP_391768.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391769.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor NP_391770.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator NP_391771.1 catalyzes the release of the N-terminal amino acid from a tripeptide NP_391772.1 Evidence 5: No homology to any previously reported sequences NP_391773.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391774.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320, 17098890; Product type pe: enzyme NP_391775.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320; Product type pe : enzyme NP_391776.2 catalyzes the formation of acetoacetate from 3-hydroxybutyrate NP_391777.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme NP_391778.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme NP_391779.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391780.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391781.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 12787499, 15849754, 16850406; Product type t: transporter NP_391783.2 Evidence 7: Gene remnant NP_391784.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16151211, 7559348, 8931328; Product type e: enzyme NP_391785.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11053381, 15849754, 16850406, 8892821; Product type t: transporter NP_391786.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1369198, 3106158, 7704256; Product type e: enzyme NP_391787.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11447120, 11580842, 11733988, 12169607, 15699035; Product type r: regulator NP_391788.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein NP_391789.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12583894, 15849754, 16850406; Product type pt: transporter NP_391790.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10481020, 16118224, 16611943, 17142894, 17229151, 17951299; Product type e : enzyme NP_391791.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pe : enzyme YP_003097796.1 Evidence 5: No homology to any previously reported sequences NP_391793.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391794.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391795.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391796.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391797.1 Evidence 5: No homology to any previously reported sequences NP_391798.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391799.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor NP_391800.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391801.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 1529529, 16306698 NP_391802.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 16849803, 9537385; Product type f: factor NP_391803.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391804.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12644671, 17210127; Product type f: factor NP_391805.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme NP_391806.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17074746, 8626332; Product type t: transporter NP_391807.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391808.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391809.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_391810.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391811.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391812.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973026, 18408032; Product type e: enzyme YP_003097797.1 Evidence 5: No homology to any previously reported sequences NP_391813.1 regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure NP_391814.1 catalyzes the degradation of histidine to urocanate and ammmonia NP_391815.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism NP_391816.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway NP_391817.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate NP_391818.2 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 7704263; Product type t: transporter NP_391819.2 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway NP_391820.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 15849754, 16850406, 8550462; Product type t: transporter NP_391821.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 11065368, 8550462; Product type e: enzyme NP_391822.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 10714997, 8550462; Product type r: regulator NP_391823.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pm: membrane component NP_391824.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pt: transporter NP_391825.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme NP_391826.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme NP_391827.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pt: transporter NP_391828.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 15849754, 16513748, 16850406, 16885442; Product type pt: transporter NP_391829.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type lp: lipoprotein NP_391830.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme NP_391831.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme NP_391832.2 Evidence 5: No homology to any previously reported sequences NP_391833.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937167; Product type pe : enzyme NP_391834.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391835.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391836.1 Evidence 5: No homology to any previously reported sequences; PubMedId: 11160890 NP_391837.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 17905812; Product type s: structure NP_391838.2 Evidence 4: Homologs of previously reported genes of unknown function NP_391839.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391840.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 8388528; Product type t: transporter NP_391841.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391842.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15849754, 15870467, 16850406; Product type t: transporter NP_391843.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15870467; Product type t: transporter NP_391844.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type e: enzyme NP_391845.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type r: regulator NP_391846.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658656, 11325924, 18310071, 9226270; Product type e: enzyme NP_391847.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 17619021, 9887260; Product type pe: enzyme NP_391848.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 9887260; Product type pe: enzyme NP_391849.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274120, 15678175, 9226270; Product type e: enzyme NP_391850.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter NP_391851.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14993306, 9226270; Product type e: enzyme NP_391852.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme NP_391853.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme NP_391854.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme NP_391855.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658656, 11566986, 16332250; Product type e: enzyme NP_391856.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 11807058, 9887260; Product type r: regulator NP_391857.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15019785, 9226270; Product type e: enzyme NP_391858.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391859.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391860.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376822, 15849754, 16850406; Product type pt: transporter NP_391861.1 molecular chaperone NP_391862.1 Evidence 5: No homology to any previously reported sequences NP_391863.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391864.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pr : regulator NP_391865.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391866.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391867.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391868.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941984; Product type pe : enzyme NP_391869.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17083466; Product type e: enzyme NP_391870.1 Evidence 5: No homology to any previously reported sequences NP_391871.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721, 17083466; Product type e: enzyme NP_391872.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter NP_391873.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 15743949; Product type e: enzyme NP_391875.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406; Product type pm: membrane component NP_391876.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391877.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317768, 15849754, 16850406; Product type pm: membrane component NP_391878.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14697267, 15317768, 15628860, 17483215; Product type e: enzyme NP_391879.2 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483215; Product type r: regulator NP_391880.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391881.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator YP_003097798.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter NP_391882.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391883.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18326573, 9298659; Product type pe: enzyme NP_391884.2 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15771780; Product type e: enzyme NP_391885.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7476858, 7642511, 8655507; Product type r: regulator NP_391886.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11468405, 1659648, 3020045; Product type e: enzyme NP_391887.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 1659648, 16850406, 3020045; Product type t: transporter NP_391888.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_391889.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 8932315; Product type e: enzyme NP_391890.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 16232966, 8932314; Product type e: enzyme NP_391891.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme NP_391892.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12867744; Product type pt : transporter NP_391893.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator YP_003097799.1 Evidence 5: No homology to any previously reported sequences NP_391894.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type t: transporter NP_391895.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 17921301; Product type t: transporter NP_391896.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type pt: transporter NP_391897.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17921301, 18307109; Product type pe: enzyme NP_391898.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989, 17921301; Product type f: factor NP_391899.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9696785; Product type e : enzyme NP_391900.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391901.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391902.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391903.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_003097800.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391904.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin NP_391905.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme YP_003097801.1 Evidence 5: No homology to any previously reported sequences NP_391906.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component NP_391907.2 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11557812, 16291680 NP_391908.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391909.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14635137; Product type pe : enzyme NP_391910.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878; Product type e: enzyme NP_391911.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878, 16816200; Product type r: regulator NP_391912.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10931887, 7540694; Product type e: enzyme NP_391913.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10648515, 15849754, 16850406, 7540694; Product type t: transporter NP_391914.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7540694, 9383188; Product type e: enzyme NP_391915.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533460, 12634342, 9194709; Product type r: regulator NP_391916.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10692364, 11133960, 16030236; Product type pe: enzyme NP_391917.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16030236; Product type pe : enzyme NP_391918.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 17307848, 17307850; Product type r: regulator NP_391919.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 16600972, 17307850; Product type r: regulator NP_391920.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 19019149; Product type rc: receptor NP_391921.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 18789936, 19019149; Product type r: regulator NP_391922.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_391923.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391924.2 unwinds double stranded DNA NP_391925.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391926.1 Evidence 5: No homology to any previously reported sequences NP_391927.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391928.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391929.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme NP_391930.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_391931.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391932.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component YP_003097802.1 Evidence 5: No homology to any previously reported sequences NP_391933.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1708381; Product type f : factor NP_391934.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391935.1 catalyzes the hydrolysis of pyrophosphate to phosphate NP_391936.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624; Product type pt : transporter NP_391937.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391938.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391939.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391940.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391941.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391942.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1938973; Product type pe : enzyme NP_391943.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process NP_391944.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391945.1 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11709313 NP_391946.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9811656; Product type pt: transporter NP_391947.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391948.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391949.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391950.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391951.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator NP_391952.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391953.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391954.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16579456; Product type pe : enzyme NP_391955.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391956.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391957.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636065, 15849754, 16850406, 17015648, 7961647; Product type t : transporter NP_391959.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391960.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator NP_391961.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter NP_391962.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391963.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391964.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9529885; Product type pt: transporter NP_391965.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12731863, 12793527; Product type e: enzyme NP_391966.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme NP_391967.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267306, 9457849, 9642180; Product type r: regulator NP_391968.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10540738, 16237020, 18203828; Product type e: enzyme NP_391969.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_391970.1 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14762004, 16549871, 10072765; Product type f: factor NP_391971.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_391972.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_391973.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114254; Product type pe : enzyme YP_003097803.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391974.1 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16847258, 16850406; Product type pt: transporter NP_391975.1 Evidence 4: Homologs of previously reported genes of unknown function NP_391976.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298; Product type f : factor NP_391977.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 18077387; Product type f: factor NP_391978.2 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component NP_391979.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807071, 15210112, 16549676; Product type f: factor NP_391980.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_391981.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_391982.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_391983.1 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12813085, 1487728; Product type f: factor NP_391984.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation NP_391985.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_391986.1 in Escherichia coli transcription of this gene is enhanced by polyamines