-- dump date   	20140619_000231
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
862962000001	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
862962000002	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
862962000003	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 1.5e-19
862962000004	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962000005	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962000006	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962000007	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
862962000008	active site
862962000009	HMMPfam hit to PF00535, Glycosyl transferase, score 8e-34
862962000010	Erythromycin esterase; Region: Erythro_esteras; cl17110
862962000011	Signal peptide predicted for BF638R0006 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.647 between residues 19 and 20
862962000012	Erythromycin esterase; Region: Erythro_esteras; cl17110
862962000013	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962000014	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962000015	HMMPfam hit to PF00534, Glycosyl transferases group, score 2.3e-08
862962000016	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
862962000017	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
862962000018	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962000019	1 probable transmembrane helix predicted for BF638R0010 by TMHMM2.0 at aa 46-68
862962000020	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
862962000021	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
862962000022	putative active site [active]
862962000023	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962000024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962000025	Walker A/P-loop; other site
862962000026	ATP binding site [chemical binding]; other site
862962000027	Q-loop/lid; other site
862962000028	ABC transporter signature motif; other site
862962000029	Walker B; other site
862962000030	D-loop; other site
862962000031	H-loop/switch region; other site
862962000032	HMMPfam hit to PF03412, Peptidase C39 family, score 9.3e-34
862962000033	5 probable transmembrane helices predicted for BF638R0011 by TMHMM2.0 at aa 170-192, 207-229, 286-305, 309-331 and 408-430
862962000034	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.5e-19
862962000035	HMMPfam hit to PF00005, ABC transporter, score 1.7e-54
862962000036	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000037	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
862962000038	Signal peptide predicted for BF638R0012 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 24 and 25
862962000039	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
862962000040	Signal peptide predicted for BF638R0013 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.995 between residues 25 and 26
862962000041	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962000042	FeS/SAM binding site; other site
862962000043	HMMPfam hit to PF04055, Radical SAM superfamily, score 3.9e-05
862962000044	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
862962000045	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962000046	Sulfatase; Region: Sulfatase; pfam00884
862962000047	Signal peptide predicted for BF638R0016 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.933 between residues 21 and 22
862962000048	HMMPfam hit to PF00884, Sulfatase, score 9.1e-46
862962000049	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
862962000050	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
862962000051	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
862962000052	4 probable transmembrane helices predicted for BF638R0017 by TMHMM2.0 at aa 12-34, 72-94, 120-142 and 181-202
862962000053	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.078
862962000054	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962000055	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
862962000056	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962000057	N-terminal plug; other site
862962000058	ligand-binding site [chemical binding]; other site
862962000059	HMMPfam hit to PF00593, TonB dependent receptor, score 7.7e-22
862962000060	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.2e-17
862962000061	Signal peptide predicted for BF638R0018 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23
862962000062	putative transporter; Provisional; Region: PRK11660
862962000063	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
862962000064	Sulfate transporter family; Region: Sulfate_transp; pfam00916
862962000065	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
862962000066	HMMPfam hit to PF01740, STAS domain, score 2.5e-13
862962000067	HMMPfam hit to PF00916, Sulfate transporter family, score 1.2e-90
862962000068	11 probable transmembrane helices predicted for BF638R0019 by TMHMM2.0 at aa 26-45, 55-89, 96-115, 119-141, 175-197, 201-218, 256-278, 293-315, 328-347, 351-368 and 388-410
862962000069	Rubrerythrin [Energy production and conversion]; Region: COG1592
862962000070	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
862962000071	binuclear metal center [ion binding]; other site
862962000072	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
862962000073	iron binding site [ion binding]; other site
862962000074	HMMPfam hit to PF02915, Rubrerythrin, score 1.6e-60
862962000075	L-aspartate oxidase; Provisional; Region: PRK09077
862962000076	L-aspartate oxidase; Provisional; Region: PRK06175
862962000077	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
862962000078	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 9.6e-08
862962000079	HMMPfam hit to PF00890, FAD binding domain, score 1.4e-129
862962000080	Signal peptide predicted for BF638R0021 by SignalP 2.0 HMM (Signal peptide probability 0.835) with cleavage site probability 0.723 between residues 20 and 21
862962000081	Domain of unknown function (DUF1200); Region: DUF1200; pfam06713
862962000082	2 probable transmembrane helices predicted for BF638R0022 by TMHMM2.0 at aa 7-29 and 33-55
862962000083	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
862962000084	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962000085	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
862962000086	Signal peptide predicted for BF638R0023 by SignalP 2.0 HMM (Signal peptide probability 0.622) with cleavage site probability 0.431 between residues 20 and 21
862962000087	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 6.4e-95
862962000088	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
862962000089	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1.7e-30
862962000090	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
862962000091	Signal peptide predicted for BF638R0024 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.745 between residues 25 and 26
862962000092	HMMPfam hit to PF02113, D-Ala-D-Ala carboxypeptidase 3 (S13) fa, score 1.2e-37
862962000093	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
862962000094	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
862962000095	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
862962000096	HMMPfam hit to PF02550, Acetyl-CoA hydrolase/transferase, score 1.6e-153
862962000097	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
862962000098	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
862962000099	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962000100	FeS/SAM binding site; other site
862962000101	TRAM domain; Region: TRAM; pfam01938
862962000102	HMMPfam hit to PF04055, Radical SAM superfamily, score 4.1e-29
862962000103	HMMPfam hit to PF01938, TRAM domain, score 3e-15
862962000104	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
862962000105	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962000106	Signal peptide predicted for BF638R0028 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 19 and 20
862962000107	HMMPfam hit to PF01120, Alpha-L-fucosidase, score 2.7e-15
862962000108	beta-D-glucuronidase; Provisional; Region: PRK10150
862962000109	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962000110	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962000111	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962000112	1 probable transmembrane helix predicted for BF638R0029 by TMHMM2.0 at aa 5-27
862962000113	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1.4e-49
862962000114	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 5.8e-06
862962000115	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 9.2e-09
862962000116	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962000117	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.1e-07
862962000118	PS00041 Bacterial regulatory proteins, araC family signature.
862962000119	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00021
862962000120	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
862962000121	DNA binding site [nucleotide binding]
862962000122	2 probable transmembrane helices predicted for BF638R0033 by TMHMM2.0 at aa 12-31 and 201-223
862962000123	NVEALA protein; Region: NVEALA; pfam14055
862962000124	NVEALA protein; Region: NVEALA; pfam14055
862962000125	ent-kaur-16-ene synthase; Region: PLN02279
862962000126	Signal peptide predicted for BF638R0039 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.977 between residues 20 and 21
862962000127	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
862962000128	2 probable transmembrane helices predicted for BF638R0040 by TMHMM2.0 at aa 7-26 and 191-213
862962000129	NVEALA protein; Region: NVEALA; pfam14055
862962000130	1 probable transmembrane helix predicted for BF638R0041 by TMHMM2.0 at aa 7-23
862962000131	NVEALA protein; Region: NVEALA; pfam14055
862962000133	putative Zn-ribbon RNA-binding protein; Provisional; Region: PRK14890
862962000134	Methyltransferase domain; Region: Methyltransf_23; pfam13489
862962000135	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962000136	S-adenosylmethionine binding site [chemical binding]; other site
862962000137	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
862962000138	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
862962000139	O-Antigen ligase; Region: Wzy_C; cl04850
862962000140	4 probable transmembrane helices predicted for BF638R0052 by TMHMM2.0 at aa 17-39, 160-182, 219-241 and 256-278
862962000141	HMMPfam hit to PF02687, Predicted permease, score 1.4e-18
862962000142	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
862962000143	2 probable transmembrane helices predicted for BF638R0053 by TMHMM2.0 at aa 13-32 and 47-69
862962000144	Bacitracin resistance protein BacA; Region: BacA; pfam02673
862962000145	HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 1.1e-77
862962000146	6 probable transmembrane helices predicted for BF638R0054 by TMHMM2.0 at aa 42-61, 82-100, 110-132, 145-167, 208-230 and 243-265
862962000147	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
862962000148	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
862962000149	RNA binding site [nucleotide binding]; other site
862962000150	active site
862962000151	HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N term, score 3.2e-50
862962000152	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
862962000153	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
862962000154	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 4.7e-68
862962000155	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
862962000156	catalytic center binding site [active]
862962000157	ATP binding site [chemical binding]; other site
862962000158	HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosph, score 9.6e-54
862962000159	S-adenosylmethionine synthetase; Validated; Region: PRK05250
862962000160	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
862962000161	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
862962000162	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
862962000163	HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-te, score 1.7e-47
862962000164	HMMPfam hit to PF02772, S-adenosylmethionine synthetase, cent, score 5e-48
862962000165	PS00376 S-adenosylmethionine synthetase signature 1.
862962000166	HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-te, score 6.4e-69
862962000167	PS00377 S-adenosylmethionine synthetase signature 2.
862962000168	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
862962000169	HMMPfam hit to PF03641, Possible lysine decarboxylase, score 5.4e-52
862962000170	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
862962000171	6 probable transmembrane helices predicted for BF638R0060 by TMHMM2.0 at aa 60-77, 111-130, 145-167, 188-206, 211-233 and 240-262
862962000172	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
862962000173	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
862962000174	active site
862962000175	HMMPfam hit to PF02602, Uroporphyrinogen-III synthase HemD, score 2.7e-06
862962000176	ribonuclease P; Reviewed; Region: rnpA; PRK01903
862962000177	PS00648 Bacterial ribonuclease P protein component signature.
862962000178	Haemolytic domain; Region: Haemolytic; pfam01809
862962000179	HMMPfam hit to PF01809, Domain of unknown function DUF37, score 2.5e-34
862962000180	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
862962000181	active site
862962000182	HMMPfam hit to PF01026, TatD related DNase, score 4.1e-12
862962000183	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
862962000184	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
862962000185	active site
862962000186	HIGH motif; other site
862962000187	dimer interface [polypeptide binding]; other site
862962000188	KMSKS motif; other site
862962000189	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 4.4e-106
862962000190	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962000191	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
862962000192	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962000193	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962000194	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962000195	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
862962000196	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962000197	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
862962000198	protein binding site [polypeptide binding]; other site
862962000199	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
862962000200	Domain interface; other site
862962000201	Peptide binding site; other site
862962000202	Active site tetrad [active]
862962000203	HMMPfam hit to PF03572, Peptidase family S41, score 2.1e-25
862962000204	Signal peptide predicted for BF638R0066 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.962 between residues 19 and 20
862962000205	arylsulfatase; Provisional; Region: PRK13759
862962000206	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962000207	HMMPfam hit to PF00884, Sulfatase, score 1.3e-26
862962000208	PS00523 Sulfatases signature 1.
862962000209	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
862962000210	HMMPfam hit to PF04962, 5-keto 4-deoxyuronate isomerase, score 6.5e-139
862962000211	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
862962000212	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
862962000213	NADP binding site [chemical binding]; other site
862962000214	homodimer interface [polypeptide binding]; other site
862962000215	active site
862962000216	HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-83
862962000217	PS00061 Short-chain dehydrogenases/reductases family signature.
862962000218	Signal peptide predicted for BF638R0070 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.286 between residues 19 and 20
862962000219	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
862962000220	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
862962000221	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00011
862962000222	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962000223	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
862962000224	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
862962000225	NodB motif; other site
862962000226	active site
862962000227	catalytic site [active]
862962000228	metal binding site [ion binding]; metal-binding site
862962000229	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 5.8e-24
862962000230	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
862962000231	13 probable transmembrane helices predicted for BF638R0073 by TMHMM2.0 at aa 7-29, 53-75, 80-102, 112-134, 139-161, 176-198, 219-241, 256-278, 294-328, 343-365, 570-589, 594-616 and 629-651
862962000232	1 probable transmembrane helix predicted for BF638R0074 by TMHMM2.0 at aa 27-49
862962000233	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
862962000234	The C-terminal domain of uncharacterized bacterial proteins; Region: Bvu_2165_C_like; cd12843
862962000235	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
862962000236	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
862962000237	HMMPfam hit to PF00005, ABC transporter, score 2.6e-39
862962000238	PS00211 ABC transporters family signature.
862962000239	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000240	Metal binding protein ZntC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: ZntC; cd01018
862962000241	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
862962000242	putative metal binding residues [ion binding]; other site
862962000243	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 2.4e-47
862962000244	Signal peptide predicted for BF638R0079 by SignalP 2.0 HMM (Signal peptide probability 0.677) with cleavage site probability 0.198 between residues 40 and 41
862962000245	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
862962000246	HMMPfam hit to PF05430, Protein of unknown function (DUF752), score 4.3e-25
862962000247	Predicted membrane protein [Function unknown]; Region: COG1238
862962000248	3 probable transmembrane helices predicted for BF638R0081 by TMHMM2.0 at aa 20-42, 102-124 and 128-147
862962000249	9 probable transmembrane helices predicted for BF638R0082 by TMHMM2.0 at aa 13-35, 55-74, 94-125, 140-162, 175-197, 222-244, 257-279, 283-300 and 307-329
862962000250	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
862962000251	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
862962000252	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
862962000253	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
862962000254	HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C doma, score 3.1e-29
862962000255	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP-gr, score 9.3e-59
862962000256	HMMPfam hit to PF02842, Phosphoribosylglycinamide synthetase, B doma, score 2.7e-32
862962000257	HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N doma, score 6.4e-48
862962000258	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
862962000259	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
862962000260	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962000261	HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 3.6e-45
862962000262	HMMPfam hit to PF00930, Dipeptidyl peptidase IV (DPP IV) N-termi, score 7.7e-111
862962000263	Signal peptide predicted for BF638R0084 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 30 and 31
862962000264	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
862962000265	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
862962000266	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
862962000267	HMMPfam hit to PF01170, Putative RNA methylase family UPF0020, score 2.1e-40
862962000268	PS00092 N-6 Adenine-specific DNA methylases signature.
862962000269	HMMPfam hit to PF02926, THUMP domain, score 2.8e-12
862962000270	serine O-acetyltransferase; Region: cysE; TIGR01172
862962000271	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
862962000272	trimer interface [polypeptide binding]; other site
862962000273	active site
862962000274	substrate binding site [chemical binding]; other site
862962000275	CoA binding site [chemical binding]; other site
862962000276	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 5
862962000277	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.052
862962000278	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962000279	binding surface
862962000280	TPR motif; other site
862962000281	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962000282	Histidine kinase; Region: His_kinase; pfam06580
862962000283	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.6
862962000284	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.023
862962000285	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.31
862962000286	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0024
862962000287	1 probable transmembrane helix predicted for BF638R0087 by TMHMM2.0 at aa 431-453
862962000288	HMMPfam hit to PF06580, Histidine kinase, score 9.3e-15
862962000289	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP9, score 1.8e-07
862962000290	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962000291	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962000292	active site
862962000293	phosphorylation site [posttranslational modification]
862962000294	intermolecular recognition site; other site
862962000295	dimerization interface [polypeptide binding]; other site
862962000296	LytTr DNA-binding domain; Region: LytTR; smart00850
862962000297	HMMPfam hit to PF00072, Response regulator receiver domain, score 9.1e-23
862962000298	1 probable transmembrane helix predicted for BF638R0089 by TMHMM2.0 at aa 7-26
862962000299	Family of unknown function (DUF3836); Region: DUF3836; pfam12930
862962000300	Signal peptide predicted for BF638R0090 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.645 between residues 25 and 26
862962000301	DNA polymerase I; Provisional; Region: PRK05755
862962000302	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
862962000303	active site
862962000304	metal binding site 1 [ion binding]; metal-binding site
862962000305	putative 5' ssDNA interaction site; other site
862962000306	metal binding site 3; metal-binding site
862962000307	metal binding site 2 [ion binding]; metal-binding site
862962000308	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
862962000309	putative DNA binding site [nucleotide binding]; other site
862962000310	putative metal binding site [ion binding]; other site
862962000311	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
862962000312	active site
862962000313	catalytic site [active]
862962000314	substrate binding site [chemical binding]; other site
862962000315	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
862962000316	active site
862962000317	DNA binding site [nucleotide binding]
862962000318	catalytic site [active]
862962000319	HMMPfam hit to PF00476, DNA polymerase family A, score 7.9e-176
862962000320	PS00447 DNA polymerase family A signature.
862962000321	HMMPfam hit to PF01612, 3'-5' exonuclease, score 1.2e-46
862962000322	HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 3.2e-44
862962000323	HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 3.8e-71
862962000324	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
862962000325	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
862962000326	substrate binding pocket [chemical binding]; other site
862962000327	chain length determination region; other site
862962000328	substrate-Mg2+ binding site; other site
862962000329	catalytic residues [active]
862962000330	aspartate-rich region 1; other site
862962000331	active site lid residues [active]
862962000332	aspartate-rich region 2; other site
862962000333	HMMPfam hit to PF00348, Polyprenyl synthetase, score 3.6e-46
862962000334	PS00723 Polyprenyl synthetases signature 1.
862962000335	PS00444 Polyprenyl synthetases signature 2.
862962000336	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
862962000337	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
862962000338	intersubunit interface [polypeptide binding]; other site
862962000339	active site
862962000340	catalytic residue [active]
862962000341	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase, score 1.6e-47
862962000342	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
862962000343	homodimer interface [polypeptide binding]; other site
862962000344	metal binding site [ion binding]; metal-binding site
862962000345	HMMPfam hit to PF03819, MazG nucleotide pyrophosphohydrolase domain, score 4.5e-23
862962000346	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
862962000347	putative active site [active]
862962000348	dimerization interface [polypeptide binding]; other site
862962000349	putative tRNAtyr binding site [nucleotide binding]; other site
862962000350	HMMPfam hit to PF02580, D-Tyr-tRNA(Tyr) deacylase, score 9.2e-62
862962000351	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
862962000352	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
862962000353	GIY-YIG motif/motif A; other site
862962000354	active site
862962000355	catalytic site [active]
862962000356	putative DNA binding site [nucleotide binding]; other site
862962000357	metal binding site [ion binding]; metal-binding site
862962000358	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
862962000359	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
862962000360	DNA binding site [nucleotide binding]
862962000361	HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 3.7e-33
862962000362	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962000363	active site
862962000364	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 8.5e-38
862962000365	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
862962000366	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
862962000367	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
862962000368	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 3.5e-191
862962000369	PS01281 Glucose inhibited division protein A family signature 2.
862962000370	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962000371	Signal peptide predicted for BF638R0102 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.393 between residues 25 and 26
862962000372	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000373	1 probable transmembrane helix predicted for BF638R0102 by TMHMM2.0 at aa 360-382
862962000374	Signal peptide predicted for BF638R0103 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.526 between residues 25 and 26
862962000375	Peptidase C10 family; Region: Peptidase_C10; pfam01640
862962000376	PS00213 Lipocalin signature.
862962000377	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
862962000378	HMMPfam hit to PF02130, Uncharacterized protein family UPF0054, score 4.7e-07
862962000379	Signal peptide predicted for BF638R0110 by SignalP 2.0 HMM (Signal peptide probability 0.876) with cleavage site probability 0.512 between residues 27 and 28
862962000380	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
862962000381	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
862962000382	10 probable transmembrane helices predicted for BF638R0113 by TMHMM2.0 at aa 4-26, 46-63, 139-161, 173-194, 204-226, 233-255, 275-294, 301-323, 358-380 and 387-409
862962000383	HMMPfam hit to PF07670, Nucleoside recognition, score 6.1e-13
862962000384	HMMPfam hit to PF07670, Nucleoside recognition, score 3.6e-14
862962000385	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
862962000386	A new structural DNA glycosylase; Region: AlkD_like; cd06561
862962000387	active site
862962000388	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
862962000389	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962000390	Walker A motif; other site
862962000391	ATP binding site [chemical binding]; other site
862962000392	Walker B motif; other site
862962000393	arginine finger; other site
862962000394	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
862962000395	HMMPfam hit to PF05496, Holliday junction DNA helicase ruvB N-termin, score 5.4e-14
862962000396	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-28
862962000397	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000398	HMMPfam hit to PF05491, Holliday junction DNA helicase ruvB C-termin, score 5.8e-48
862962000399	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962000400	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962000401	14 probable transmembrane helices predicted for BF638R0116 by TMHMM2.0 at aa 35-57, 61-83, 96-118, 133-155, 162-184, 204-223, 243-262, 282-304, 329-351, 356-378, 391-410, 415-437, 450-467 and 472-491
862962000402	Domain of unknown function (DUF389); Region: DUF389; pfam04087
862962000403	7 probable transmembrane helices predicted for BF638R0117 by TMHMM2.0 at aa 43-62, 67-89, 102-124, 134-156, 163-185, 195-217 and 237-256
862962000404	HMMPfam hit to PF04087, Domain of unknown function (DUF389), score 9.7e-83
862962000405	Peptidase S46; Region: Peptidase_S46; pfam10459
862962000406	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
862962000407	EamA-like transporter family; Region: EamA; pfam00892
862962000408	10 probable transmembrane helices predicted for BF638R0119 by TMHMM2.0 at aa 5-27, 37-55, 67-86, 96-115, 122-141, 146-168, 181-203, 209-231, 238-260 and 265-285
862962000409	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.6e-14
862962000410	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.7e-11
862962000411	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
862962000412	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
862962000413	ATP binding site [chemical binding]; other site
862962000414	Mg++ binding site [ion binding]; other site
862962000415	motif III; other site
862962000416	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962000417	nucleotide binding region [chemical binding]; other site
862962000418	ATP-binding site [chemical binding]; other site
862962000419	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
862962000420	RNA binding site [nucleotide binding]; other site
862962000421	HMMPfam hit to PF03880, DbpA RNA binding domain, score 3.6e-09
862962000422	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000423	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 5.1e-34
862962000424	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 8.3e-62
862962000425	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
862962000426	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000427	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
862962000428	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
862962000429	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
862962000430	PS00383 Tyrosine specific protein phosphatases active site.
862962000431	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
862962000432	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
862962000433	putative substrate binding site [chemical binding]; other site
862962000434	putative ATP binding site [chemical binding]; other site
862962000435	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 4e-28
862962000436	PS00584 pfkB family of carbohydrate kinases signature 2.
862962000437	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
862962000438	putative active site [active]
862962000439	HMMPfam hit to PF01380, SIS domain, score 6.6e-25
862962000440	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
862962000441	HMMPfam hit to PF03641, Possible lysine decarboxylase, score 8.2e-24
862962000442	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962000443	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
862962000444	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962000445	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 2.5e-35
862962000446	PS00143 Insulinase family, zinc-binding region signature.
862962000447	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 4e-41
862962000448	Signal peptide predicted for BF638R0127 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.828 between residues 28 and 29
862962000449	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
862962000450	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962000451	Coenzyme A binding pocket [chemical binding]; other site
862962000452	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.2e-07
862962000453	mannonate dehydratase; Provisional; Region: PRK03906
862962000454	mannonate dehydratase; Region: uxuA; TIGR00695
862962000455	HMMPfam hit to PF03786, D-mannonate dehydratase (UxuA), score 2.1e-211
862962000456	D-mannonate oxidoreductase; Provisional; Region: PRK08277
862962000457	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962000458	NAD(P) binding site [chemical binding]; other site
862962000459	active site
862962000460	HMMPfam hit to PF00106, short chain dehydrogenase, score 4.2e-59
862962000461	PS00061 Short-chain dehydrogenases/reductases family signature.
862962000462	WbqC-like protein family; Region: WbqC; pfam08889
862962000463	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
862962000464	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
862962000465	Catalytic site [active]
862962000466	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
862962000467	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
862962000468	HMMPfam hit to PF00717, Peptidase S24-like, score 3e-06
862962000469	Signal peptide predicted for BF638R0132 by SignalP 2.0 HMM (Signal peptide probability 0.948) with cleavage site probability 0.428 between residues 36 and 37
862962000470	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
862962000471	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
862962000472	PS00761 Signal peptidases I signature 3.
862962000473	2 probable transmembrane helices predicted for BF638R0133 by TMHMM2.0 at aa 21-43 and 63-85
862962000474	dihydrodipicolinate reductase; Provisional; Region: PRK00048
862962000475	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
862962000476	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
862962000477	HMMPfam hit to PF05173, Dihydrodipicolinate reductase, C-terminus, score 2.1e-26
862962000478	HMMPfam hit to PF01113, Dihydrodipicolinate reductase, N-terminus, score 2.8e-17
862962000479	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
862962000480	PS00136 Serine proteases, subtilase family, aspartic acid active site.
862962000481	Signal peptide predicted for BF638R0137 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.496 between residues 32 and 33
862962000482	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
862962000483	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
862962000484	FMN binding site [chemical binding]; other site
862962000485	active site
862962000486	catalytic residues [active]
862962000487	substrate binding site [chemical binding]; other site
862962000488	PS01136 Uncharacterized protein family UPF0034 signature.
862962000489	Signal peptide predicted for BF638R0139 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.584 between residues 21 and 22
862962000490	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
862962000491	putative ligand binding site [chemical binding]; other site
862962000492	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK12461
862962000493	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
862962000494	active site
862962000495	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.022
862962000496	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0065
862962000497	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962000498	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1e-33
862962000499	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.5e-09
862962000500	Signal peptide predicted for BF638R0142 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.703 between residues 49 and 50
862962000501	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000502	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962000503	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962000504	12 probable transmembrane helices predicted for BF638R0143 by TMHMM2.0 at aa 12-34, 335-357, 364-386, 396-415, 436-458, 473-495, 531-553, 867-889, 896-918, 938-960, 984-1006 and 1016-1038
862962000505	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962000506	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
862962000507	E3 interaction surface; other site
862962000508	lipoyl attachment site [posttranslational modification]; other site
862962000509	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962000510	HMMPfam hit to PF00529, HlyD family secretion protein, score 3.8e-22
862962000511	Signal peptide predicted for BF638R0144 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.584 between residues 32 and 33
862962000512	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
862962000513	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962000514	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962000515	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962000516	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
862962000517	HMMPfam hit to PF02930, Beta galactosidase small chain, C ter, score 6.1e-18
862962000518	HMMPfam hit to PF02929, Beta galactosidase small chain, N ter, score 7.5e-35
862962000519	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 4.9e-114
862962000520	PS00719 Glycosyl hydrolases family 2 signature 1.
862962000521	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 2e-24
862962000522	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 7.1e-89
862962000523	Signal peptide predicted for BF638R0145 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.926 between residues 19 and 20
862962000524	Bacterial Ig-like domain; Region: Big_5; pfam13205
862962000525	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962000526	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
862962000527	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
862962000528	CoenzymeA binding site [chemical binding]; other site
862962000529	subunit interaction site [polypeptide binding]; other site
862962000530	PHB binding site; other site
862962000531	HMMPfam hit to PF03061, Thioesterase superfamily, score 9.5e-17
862962000532	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
862962000533	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
862962000534	active site
862962000535	HIGH motif; other site
862962000536	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
862962000537	KMSKS motif; other site
862962000538	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
862962000539	tRNA binding surface [nucleotide binding]; other site
862962000540	anticodon binding site; other site
862962000541	HMMPfam hit to PF01406, tRNA synthetases class I (C) catalytic d, score 1.2e-136
862962000542	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962000543	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
862962000544	active site
862962000545	motif I; other site
862962000546	motif II; other site
862962000547	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962000548	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 7.3e-11
862962000549	PS01229 Hypothetical cof family signature 2.
862962000550	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
862962000551	DNA binding site [nucleotide binding]
862962000552	2 probable transmembrane helices predicted for BF638R0151 by TMHMM2.0 at aa 6-25 and 192-214
862962000553	NVEALA protein; Region: NVEALA; pfam14055
862962000554	1 probable transmembrane helix predicted for BF638R0152 by TMHMM2.0 at aa 13-32
862962000555	NVEALA protein; Region: NVEALA; pfam14055
862962000556	Signal peptide predicted for BF638R0153 by SignalP 2.0 HMM (Signal peptide probability 0.885) with cleavage site probability 0.660 between residues 18 and 19
862962000557	NVEALA protein; Region: NVEALA; pfam14055
862962000558	Signal peptide predicted for BF638R0154 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.810 between residues 22 and 23
862962000559	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962000560	HMMPfam hit to PF07610, Protein of unknown function (DUF1573), score 1.1e-11
862962000561	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962000562	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
862962000563	HMMPfam hit to PF01344, Kelch motif, score 7.2e-05
862962000564	HMMPfam hit to PF01344, Kelch motif, score 0.0046
862962000565	HMMPfam hit to PF01344, Kelch motif, score 0.51
862962000566	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962000567	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962000568	active site
862962000569	phosphorylation site [posttranslational modification]
862962000570	intermolecular recognition site; other site
862962000571	dimerization interface [polypeptide binding]; other site
862962000572	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962000573	DNA binding site [nucleotide binding]
862962000574	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.7e-40
862962000575	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.5e-17
862962000576	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
862962000577	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
862962000578	dimerization interface [polypeptide binding]; other site
862962000579	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962000580	dimer interface [polypeptide binding]; other site
862962000581	phosphorylation site [posttranslational modification]
862962000582	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962000583	ATP binding site [chemical binding]; other site
862962000584	Mg2+ binding site [ion binding]; other site
862962000585	G-X-G motif; other site
862962000586	2 probable transmembrane helices predicted for BF638R0159 by TMHMM2.0 at aa 7-29 and 152-174
862962000587	HMMPfam hit to PF00672, HAMP domain, score 2.9e-13
862962000588	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 9.9e-15
862962000589	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.5e-21
862962000590	magnesium-transporting ATPase; Provisional; Region: PRK15122
862962000591	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
862962000592	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
862962000593	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
862962000594	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962000595	motif II; other site
862962000596	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
862962000597	HMMPfam hit to PF00690, Cation transporter/ATPase, N-terminus, score 1.4e-12
862962000598	8 probable transmembrane helices predicted for BF638R0160 by TMHMM2.0 at aa 69-91, 106-124, 272-291, 301-323, 690-712, 754-776, 817-839 and 854-876
862962000599	HMMPfam hit to PF00122, E1-E2 ATPase, score 4.5e-72
862962000600	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 6e-15
862962000601	PS00154 E1-E2 ATPases phosphorylation site.
862962000602	Signal peptide predicted for BF638R0162 by SignalP 2.0 HMM (Signal peptide probability 0.960) with cleavage site probability 0.531 between residues 25 and 26
862962000603	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000604	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
862962000605	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
862962000606	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
862962000607	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962000608	putative Mg++ binding site [ion binding]; other site
862962000609	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962000610	nucleotide binding region [chemical binding]; other site
862962000611	ATP-binding site [chemical binding]; other site
862962000612	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 7.6e-20
862962000613	HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 9.5e-76
862962000614	tRNA-specific 2-thiouridylase MnmA; Provisional; Region: mnmA; PRK14665
862962000615	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
862962000616	Ligand Binding Site [chemical binding]; other site
862962000617	HMMPfam hit to PF03054, tRNA methyl transferase, score 1.1e-110
862962000618	GH3 auxin-responsive promoter; Region: GH3; pfam03321
862962000619	HMMPfam hit to PF03321, GH3 auxin-responsive promoter, score 1e-08
862962000620	6-phosphofructokinase; Provisional; Region: PRK03202
862962000621	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
862962000622	active site
862962000623	ADP/pyrophosphate binding site [chemical binding]; other site
862962000624	dimerization interface [polypeptide binding]; other site
862962000625	allosteric effector site; other site
862962000626	fructose-1,6-bisphosphate binding site; other site
862962000627	HMMPfam hit to PF00365, Phosphofructokinase, score 2.5e-95
862962000628	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
862962000629	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
862962000630	dimerization interface [polypeptide binding]; other site
862962000631	active site
862962000632	metal binding site [ion binding]; metal-binding site
862962000633	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
862962000634	dsRNA binding site [nucleotide binding]; other site
862962000635	HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 2.7e-13
862962000636	HMMPfam hit to PF00636, RNase3 domain, score 7.7e-35
862962000637	PS00517 Ribonuclease III family signature.
862962000638	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
862962000639	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
862962000640	dimer interface [polypeptide binding]; other site
862962000641	active site
862962000642	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 1.3e-64
862962000643	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 4.1e-77
862962000644	acyl carrier protein; Provisional; Region: acpP; PRK00982
862962000645	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962000646	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 7.4e-21
862962000647	PS00012 Phosphopantetheine attachment site.
862962000648	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
862962000649	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
862962000650	active site
862962000651	substrate binding site [chemical binding]; other site
862962000652	cosubstrate binding site; other site
862962000653	catalytic site [active]
862962000654	HMMPfam hit to PF00551, Formyl transferase, score 4.7e-54
862962000655	erythronate-4-phosphate dehydrogenase; Validated; Region: PRK00257
862962000656	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
862962000657	ligand binding site [chemical binding]; other site
862962000658	NAD binding site [chemical binding]; other site
862962000659	catalytic site [active]
862962000660	homodimer interface [polypeptide binding]; other site
862962000661	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.6e-34
862962000662	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.1e-20
862962000663	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962000664	active site
862962000665	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; cl17488
862962000666	PS00109 Tyrosine protein kinases specific active-site signature.
862962000667	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
862962000668	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
862962000669	Ligand binding site; other site
862962000670	metal-binding site
862962000671	HMMPfam hit to PF01501, Glycosyl transferase family, score 9.5e-49
862962000672	Putative lipopolysaccharide-modifying enzyme; Region: CAP10; smart00672
862962000673	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962000674	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
862962000675	Substrate binding site; other site
862962000676	metal-binding site
862962000677	HMMPfam hit to PF00535, Glycosyl transferase, score 2e-20
862962000678	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962000679	active site
862962000680	HMMPfam hit to PF00535, Glycosyl transferase, score 1.2e-44
862962000681	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962000682	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962000683	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
862962000684	Walker A/P-loop; other site
862962000685	ATP binding site [chemical binding]; other site
862962000686	Q-loop/lid; other site
862962000687	ABC transporter signature motif; other site
862962000688	Walker B; other site
862962000689	D-loop; other site
862962000690	H-loop/switch region; other site
862962000691	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 5.2e-31
862962000692	5 probable transmembrane helices predicted for BF638R0178 by TMHMM2.0 at aa 21-43, 90-112, 180-202, 285-304 and 311-328
862962000693	HMMPfam hit to PF00005, ABC transporter, score 1e-54
862962000694	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000695	PS00211 ABC transporters family signature.
862962000696	Signal peptide predicted for BF638R0179 by SignalP 2.0 HMM (Signal peptide probability 0.959) with cleavage site probability 0.757 between residues 26 and 27
862962000697	Predicted double-stranded RNA/RNA-DNA hybrid binding protein [General function prediction only]; Region: COG3341
862962000698	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
862962000699	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cd06222
862962000700	active site
862962000701	RNA/DNA hybrid binding site [nucleotide binding]; other site
862962000702	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
862962000703	dimer interface [polypeptide binding]; other site
862962000704	FMN binding site [chemical binding]; other site
862962000705	shikimate kinase; Reviewed; Region: aroK; PRK00131
862962000706	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
862962000707	ADP binding site [chemical binding]; other site
862962000708	magnesium binding site [ion binding]; other site
862962000709	putative shikimate binding site; other site
862962000710	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000711	HMMPfam hit to PF01202, Shikimate kinase, score 4.8e-55
862962000712	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
862962000713	Sel1-like repeats; Region: SEL1; smart00671
862962000714	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
862962000715	Sel1-like repeats; Region: SEL1; smart00671
862962000716	Sel1-like repeats; Region: SEL1; smart00671
862962000717	Sel1-like repeats; Region: SEL1; smart00671
862962000718	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
862962000719	Sel1-like repeats; Region: SEL1; smart00671
862962000720	Sel1-like repeats; Region: SEL1; smart00671
862962000721	Sel1-like repeats; Region: SEL1; smart00671
862962000722	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000723	HSP90 family protein; Provisional; Region: PRK14083
862962000724	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962000725	ATP binding site [chemical binding]; other site
862962000726	Mg2+ binding site [ion binding]; other site
862962000727	G-X-G motif; other site
862962000728	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 0.0025
862962000729	arginine decarboxylase; Provisional; Region: PRK05354
862962000730	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
862962000731	dimer interface [polypeptide binding]; other site
862962000732	active site
862962000733	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
862962000734	catalytic residues [active]
862962000735	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
862962000736	HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 1.2e-60
862962000737	PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
862962000738	PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
862962000739	HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 3.5e-09
862962000740	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
862962000741	nucleotide binding site [chemical binding]; other site
862962000742	N-acetyl-L-glutamate binding site [chemical binding]; other site
862962000743	HMMPfam hit to PF00696, Amino acid kinase family, score 2.6e-26
862962000744	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962000745	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962000746	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962000747	DNA binding residues [nucleotide binding]
862962000748	HMMPfam hit to PF04542, Sigma-70 region, score 1.2e-12
862962000749	HMMPfam hit to PF04545, Sigma-70, region, score 2.7e-15
862962000750	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
862962000751	Signal peptide predicted for BF638R0192 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 19 and 20
862962000752	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
862962000753	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
862962000754	Signal peptide predicted for BF638R0193 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.491 between residues 22 and 23
862962000755	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000756	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
862962000757	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
862962000758	Signal peptide predicted for BF638R0194 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.663 between residues 25 and 26
862962000759	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000760	Protein of unknown function DUF45; Region: DUF45; pfam01863
862962000761	HMMPfam hit to PF01863, Protein of unknown function DUF45, score 1.3e-07
862962000762	1 probable transmembrane helix predicted for BF638R0196 by TMHMM2.0 at aa 12-34
862962000763	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
862962000764	2 probable transmembrane helices predicted for BF638R0197 by TMHMM2.0 at aa 30-49 and 225-247
862962000765	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000766	NVEALA protein; Region: NVEALA; pfam14055
862962000767	Signal peptide predicted for BF638R0198 by SignalP 2.0 HMM (Signal peptide probability 0.932) with cleavage site probability 0.398 between residues 23 and 24
862962000768	Signal peptide predicted for BF638R0199 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.429 between residues 23 and 24
862962000769	putative conjugative transposon 55 Kb
862962000770	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962000771	Int/Topo IB signature motif; other site
862962000772	HMMPfam hit to PF00589, Phage integrase family, score 1.2e-06
862962000773	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
862962000774	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962000775	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962000776	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962000777	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962000778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962000779	S-adenosylmethionine binding site [chemical binding]; other site
862962000780	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
862962000781	DEAD-like helicases superfamily; Region: DEXDc; smart00487
862962000782	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
862962000783	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
862962000784	nucleotide binding region [chemical binding]; other site
862962000785	helicase superfamily c-terminal domain; Region: HELICc; smart00490
862962000786	ATP-binding site [chemical binding]; other site
862962000787	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0039
862962000788	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
862962000789	DNA topoisomerase III; Provisional; Region: PRK07726
862962000790	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
862962000791	active site
862962000792	putative interdomain interaction site [polypeptide binding]; other site
862962000793	putative metal-binding site [ion binding]; other site
862962000794	putative nucleotide binding site [chemical binding]; other site
862962000795	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962000796	domain I; other site
862962000797	DNA binding groove [nucleotide binding]
862962000798	phosphate binding site [ion binding]; other site
862962000799	domain II; other site
862962000800	domain III; other site
862962000801	nucleotide binding site [chemical binding]; other site
862962000802	catalytic site [active]
862962000803	domain IV; other site
862962000804	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
862962000805	HMMPfam hit to PF01131, DNA topoisomerase, score 2e-78
862962000806	HMMPfam hit to PF01751, Toprim domain, score 3.5e-09
862962000807	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
862962000808	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
862962000809	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
862962000810	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000811	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962000812	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962000813	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 9e-11
862962000814	1 probable transmembrane helix predicted for BF638R0212 by TMHMM2.0 at aa 5-27
862962000815	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962000816	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962000817	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962000818	Signal peptide predicted for BF638R0213 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.904 between residues 21 and 22
862962000819	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.4e-22
862962000820	HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-09
862962000821	Phospholipid methyltransferase; Region: PEMT; cl17370
862962000822	4 probable transmembrane helices predicted for BF638R0215 by TMHMM2.0 at aa 15-34, 55-77, 81-103 and 124-158
862962000823	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962000824	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962000825	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962000826	Walker A/P-loop; other site
862962000827	ATP binding site [chemical binding]; other site
862962000828	Q-loop/lid; other site
862962000829	ABC transporter signature motif; other site
862962000830	Walker B; other site
862962000831	D-loop; other site
862962000832	H-loop/switch region; other site
862962000833	6 probable transmembrane helices predicted for BF638R0216 by TMHMM2.0 at aa 21-43, 58-80, 136-158, 168-190, 252-274 and 284-306
862962000834	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 3.7e-05
862962000835	HMMPfam hit to PF00005, ABC transporter, score 3.2e-63
862962000836	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000837	PS00211 ABC transporters family signature.
862962000838	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962000839	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962000840	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962000841	Walker A/P-loop; other site
862962000842	ATP binding site [chemical binding]; other site
862962000843	Q-loop/lid; other site
862962000844	ABC transporter signature motif; other site
862962000845	Walker B; other site
862962000846	D-loop; other site
862962000847	H-loop/switch region; other site
862962000848	6 probable transmembrane helices predicted for BF638R0217 by TMHMM2.0 at aa 22-44, 79-101, 141-163, 168-190, 257-279 and 289-311
862962000849	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.5e-16
862962000850	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000851	HMMPfam hit to PF00005, ABC transporter, score 2.4e-53
862962000852	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000853	PS00211 ABC transporters family signature.
862962000856	Protein of unknown function (DUF1706); Region: DUF1706; cl01748
862962000857	Signal peptide predicted for BF638R0222 by SignalP 2.0 HMM (Signal peptide probability 0.814) with cleavage site probability 0.448 between residues 20 and 21
862962000858	Peptidase C10 family; Region: Peptidase_C10; pfam01640
862962000859	Signal peptide predicted for BF638R0223 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.523 between residues 20 and 21
862962000860	Signal peptide predicted for BF638R0225 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.958 between residues 23 and 24
862962000861	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962000862	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962000863	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962000864	DNA binding residues [nucleotide binding]
862962000865	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962000866	HMMPfam hit to PF04542, Sigma-70 region, score 8.3e-05
862962000867	3 probable transmembrane helices predicted for BF638R0228 by TMHMM2.0 at aa 54-73, 88-110 and 123-145
862962000868	YWFCY protein; Region: YWFCY; pfam14293
862962000869	AAA-like domain; Region: AAA_10; pfam12846
862962000870	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
862962000871	5 probable transmembrane helices predicted for BF638R0229 by TMHMM2.0 at aa 21-43, 58-80, 93-115, 125-144 and 314-333
862962000872	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000873	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
862962000874	HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 9.2e-11
862962000875	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
862962000876	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962000877	P-loop; other site
862962000878	Magnesium ion binding site [ion binding]; other site
862962000879	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962000880	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962000881	Signal peptide predicted for BF638R0236 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.836 between residues 21 and 22
862962000882	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
862962000883	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962000884	P-loop; other site
862962000885	Magnesium ion binding site [ion binding]; other site
862962000886	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
862962000887	3 probable transmembrane helices predicted for BF638R0239 by TMHMM2.0 at aa 7-26, 46-63 and 76-98
862962000888	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
862962000889	2 probable transmembrane helices predicted for BF638R0240 by TMHMM2.0 at aa 21-43 and 48-70
862962000890	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
862962000891	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
862962000892	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000893	PS00017 ATP/GTP-binding site motif A (P-loop).
862962000894	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
862962000895	Signal peptide predicted for BF638R0242 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 21 and 22
862962000896	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
862962000897	6 probable transmembrane helices predicted for BF638R0243 by TMHMM2.0 at aa 30-52, 67-89, 193-212, 222-244, 272-294 and 309-331
862962000898	HMMPfam hit to PF07863, Homologues of TraJ from Bacteroides conju, score 1.7e-26
862962000899	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
862962000900	Signal peptide predicted for BF638R0244 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 42 and 43
862962000901	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
862962000902	1 probable transmembrane helix predicted for BF638R0245 by TMHMM2.0 at aa 28-50
862962000903	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
862962000904	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
862962000905	1 probable transmembrane helix predicted for BF638R0246 by TMHMM2.0 at aa 29-48
862962000906	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
862962000907	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
862962000908	Signal peptide predicted for BF638R0247 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 19 and 20
862962000909	Conjugative transposon protein TraO; Region: TraO; pfam10626
862962000910	Signal peptide predicted for BF638R0248 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 22 and 23
862962000911	DNA primase (bacterial type) [DNA replication, recombination, and repair]; Region: DnaG; COG0358
862962000912	CHC2 zinc finger; Region: zf-CHC2; cl17510
862962000913	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
862962000914	active site
862962000915	metal binding site [ion binding]; metal-binding site
862962000916	interdomain interaction site; other site
862962000917	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
862962000918	Signal peptide predicted for BF638R0250 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.781 between residues 26 and 27
862962000919	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
862962000920	catalytic residue [active]
862962000921	Signal peptide predicted for BF638R0251 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.960 between residues 24 and 25
862962000922	Cupin domain; Region: Cupin_2; cl17218
862962000923	HMMPfam hit to PF07883, Cupin domain, score 0.00039
862962000924	Uncharacterized conserved protein [Function unknown]; Region: COG2461
862962000925	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
862962000926	PcfJ-like protein; Region: PcfJ; pfam14284
862962000927	Antirestriction protein (ArdA); Region: ArdA; cl01953
862962000928	HMMPfam hit to PF07275, Antirestriction protein (ArdA), score 3.6e-37
862962000929	PcfK-like protein; Region: PcfK; pfam14058
862962000930	2 probable transmembrane helices predicted for BF638R0261 by TMHMM2.0 at aa 7-29 and 44-66
862962000931	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
862962000932	DNA-binding site [nucleotide binding]; DNA binding site
862962000933	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
862962000934	putative dimerization interface [polypeptide binding]; other site
862962000935	putative ligand binding site [chemical binding]; other site
862962000936	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.9e-14
862962000937	PS00043 Bacterial regulatory proteins, gntR family signature.
862962000938	L-fucose isomerase; Provisional; Region: fucI; PRK10991
862962000939	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
862962000940	hexamer (dimer of trimers) interface [polypeptide binding]; other site
862962000941	trimer interface [polypeptide binding]; other site
862962000942	substrate binding site [chemical binding]; other site
862962000943	Mn binding site [ion binding]; other site
862962000944	HMMPfam hit to PF07881, L-fucose isomerase, first N-terminal do, score 1.5e-127
862962000945	HMMPfam hit to PF07882, L-fucose isomerase, second N-terminal d, score 2e-139
862962000946	HMMPfam hit to PF02952, L-fucose isomerase, C-terminal domain, score 1.6e-113
862962000947	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
862962000948	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
862962000949	dimer interface [polypeptide binding]; other site
862962000950	active site
862962000951	metal binding site [ion binding]; metal-binding site
862962000952	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 4.2e-157
862962000953	PS00913 Iron-containing alcohol dehydrogenases signature 1.
862962000954	PS00060 Iron-containing alcohol dehydrogenases signature 2.
862962000955	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596
862962000956	active site
862962000957	intersubunit interface [polypeptide binding]; other site
862962000958	Zn2+ binding site [ion binding]; other site
862962000959	HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 4.7e-46
862962000960	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
862962000961	N- and C-terminal domain interface [polypeptide binding]; other site
862962000962	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
862962000963	active site
862962000964	putative catalytic site [active]
862962000965	metal binding site [ion binding]; metal-binding site
862962000966	ATP binding site [chemical binding]; other site
862962000967	carbohydrate binding site [chemical binding]; other site
862962000968	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 3e-10
862962000969	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
862962000970	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962000971	putative substrate translocation pore; other site
862962000972	12 probable transmembrane helices predicted for BF638R0269 by TMHMM2.0 at aa 13-32, 55-77, 84-103, 113-135, 147-169, 199-221, 252-274, 294-316, 321-343, 348-370, 377-399 and 404-426
862962000973	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.8e-13
862962000974	Signal peptide predicted for BF638R0270 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.642 between residues 27 and 28
862962000975	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962000976	2 probable transmembrane helices predicted for BF638R0271 by TMHMM2.0 at aa 15-37 and 58-75
862962000977	hypothetical protein; Validated; Region: PRK02001
862962000978	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
862962000979	heptamer interface [polypeptide binding]; other site
862962000980	Sm1 motif; other site
862962000981	hexamer interface [polypeptide binding]; other site
862962000982	RNA binding site [nucleotide binding]; other site
862962000983	Sm2 motif; other site
862962000984	HMMPfam hit to PF02576, Uncharacterised BCR, YhbC family COG0779, score 3.8e-09
862962000985	transcription termination factor NusA; Region: NusA; TIGR01953
862962000986	NusA N-terminal domain; Region: NusA_N; pfam08529
862962000987	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
862962000988	RNA binding site [nucleotide binding]; other site
862962000989	homodimer interface [polypeptide binding]; other site
862962000990	NusA-like KH domain; Region: KH_5; pfam13184
862962000991	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
862962000992	G-X-X-G motif; other site
862962000993	translation initiation factor IF-2; Region: IF-2; TIGR00487
862962000994	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
862962000995	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
862962000996	G1 box; other site
862962000997	putative GEF interaction site [polypeptide binding]; other site
862962000998	GTP/Mg2+ binding site [chemical binding]; other site
862962000999	Switch I region; other site
862962001000	G2 box; other site
862962001001	G3 box; other site
862962001002	Switch II region; other site
862962001003	G4 box; other site
862962001004	G5 box; other site
862962001005	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
862962001006	Translation-initiation factor 2; Region: IF-2; pfam11987
862962001007	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
862962001008	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 6.8e-12
862962001009	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 3.5e-50
862962001010	HMMPfam hit to PF01926, GTPase of unknown function, score 7.8e-08
862962001011	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001012	HMMPfam hit to PF03144, Elongation factor Tu domain, score 6e-14
862962001013	HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.3e-06
862962001014	Colicin V production protein; Region: Colicin_V; pfam02674
862962001015	HMMPfam hit to PF02674, Colicin V production protein, score 4.5e-19
862962001016	5 probable transmembrane helices predicted for BF638R0276 by TMHMM2.0 at aa 4-21, 28-50, 60-82, 103-125 and 140-157
862962001017	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
862962001018	putative ABC transporter; Region: ycf24; CHL00085
862962001019	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 9.9e-137
862962001020	Signal peptide predicted for BF638R0278 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.998 between residues 21 and 22
862962001021	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
862962001022	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
862962001023	FeS assembly ATPase SufC; Region: sufC; TIGR01978
862962001024	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
862962001025	Walker A/P-loop; other site
862962001026	ATP binding site [chemical binding]; other site
862962001027	Q-loop/lid; other site
862962001028	ABC transporter signature motif; other site
862962001029	Walker B; other site
862962001030	D-loop; other site
862962001031	H-loop/switch region; other site
862962001032	HMMPfam hit to PF00005, ABC transporter, score 6.1e-29
862962001033	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001034	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
862962001035	FeS assembly protein SufD; Region: sufD; TIGR01981
862962001036	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 6.6e-37
862962001037	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
862962001038	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
862962001039	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962001040	catalytic residue [active]
862962001041	HMMPfam hit to PF00266, Aminotransferase class-V, score 8.5e-15
862962001042	hypothetical protein; Provisional; Region: PRK02877
862962001043	HMMPfam hit to PF01906, Domain of unknown function DUF74, score 1.6e-57
862962001044	alpha-galactosidase; Region: PLN02808; cl17638
862962001045	Carbohydrate Binding Module family 35 (CBM35); appended mainly to enzymes that bind alpha-D-galactose (CBM35-Gal), including glycoside hydrolase (GH) families GH31 and GH43; Region: CBM35_galactosidase-like; cd04081
862962001046	Ca binding site [ion binding]; other site
862962001047	HMMPfam hit to PF02065, Melibiase, score 4.2e-10
862962001048	Signal peptide predicted for BF638R0283 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.942 between residues 24 and 25
862962001049	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962001050	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962001051	SusD family; Region: SusD; pfam07980
862962001052	Signal peptide predicted for BF638R0284 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.956 between residues 18 and 19
862962001053	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962001054	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001055	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001056	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001057	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962001058	HMMPfam hit to PF00593, TonB dependent receptor, score 1.9e-19
862962001059	PS00237 G-protein coupled receptors signature.
862962001060	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.1e-17
862962001061	1 probable transmembrane helix predicted for BF638R0285 by TMHMM2.0 at aa 13-35
862962001062	FecR protein; Region: FecR; pfam04773
862962001063	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962001064	HMMPfam hit to PF04773, FecR protein, score 2.7e-24
862962001065	1 probable transmembrane helix predicted for BF638R0286 by TMHMM2.0 at aa 84-106
862962001066	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962001067	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962001068	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962001069	DNA binding residues [nucleotide binding]
862962001070	HMMPfam hit to PF04545, Sigma-70, region, score 2.3e-09
862962001071	HMMPfam hit to PF04542, Sigma-70 region, score 5.1e-13
862962001072	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
862962001073	Melibiase; Region: Melibiase; pfam02065
862962001074	HMMPfam hit to PF02065, Melibiase, score 4e-126
862962001075	Signal peptide predicted for BF638R0288 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.993 between residues 33 and 34
862962001076	Signal peptide predicted for BF638R0289 by SignalP 2.0 HMM (Signal peptide probability 0.834) with cleavage site probability 0.481 between residues 21 and 22
862962001077	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001078	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
862962001079	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
862962001080	HMMPfam hit to PF03030, Inorganic H+ pyrophosphatase, score 4.4e-296
862962001081	16 probable transmembrane helices predicted for BF638R0290 by TMHMM2.0 at aa 4-23, 58-77, 81-103, 132-154, 169-191, 244-266, 276-298, 311-333, 338-357, 387-409, 424-446, 491-508, 554-576, 622-641, 645-667 and 711-733
862962001082	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
862962001083	RNA/DNA hybrid binding site [nucleotide binding]; other site
862962001084	active site
862962001085	HMMPfam hit to PF01351, Ribonuclease HII, score 6.9e-67
862962001086	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
862962001087	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
862962001088	Cl binding site [ion binding]; other site
862962001089	oligomer interface [polypeptide binding]; other site
862962001090	HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 6.9e-07
862962001091	2 probable transmembrane helices predicted for BF638R0292 by TMHMM2.0 at aa 253-270 and 280-302
862962001092	phosphoglyceromutase; Provisional; Region: PRK05434
862962001093	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
862962001094	HMMPfam hit to PF06415, BPG-independent PGAM N-terminus (iPGM_N, score 4e-232
862962001095	HMMPfam hit to PF01676, Metalloenzyme superfamily, score 1.2e-35
862962001096	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001097	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001098	dimer interface [polypeptide binding]; other site
862962001099	phosphorylation site [posttranslational modification]
862962001100	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001101	ATP binding site [chemical binding]; other site
862962001102	Mg2+ binding site [ion binding]; other site
862962001103	G-X-G motif; other site
862962001104	Signal peptide predicted for BF638R0294 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.829 between residues 20 and 21
862962001105	1 probable transmembrane helix predicted for BF638R0294 by TMHMM2.0 at aa 92-114
862962001106	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.4e-14
862962001107	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.4e-31
862962001108	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001109	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001110	dimer interface [polypeptide binding]; other site
862962001111	phosphorylation site [posttranslational modification]
862962001112	2 probable transmembrane helices predicted for BF638R0295 by TMHMM2.0 at aa 5-27 and 395-417
862962001113	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 8.6e-08
862962001114	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
862962001115	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
862962001116	Signal peptide predicted for BF638R0297 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.449 between residues 30 and 31
862962001117	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
862962001118	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001119	ATP binding site [chemical binding]; other site
862962001120	Mg2+ binding site [ion binding]; other site
862962001121	G-X-G motif; other site
862962001122	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
862962001123	anchoring element; other site
862962001124	dimer interface [polypeptide binding]; other site
862962001125	ATP binding site [chemical binding]; other site
862962001126	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
862962001127	active site
862962001128	putative metal-binding site [ion binding]; other site
862962001129	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
862962001130	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 2.8e-41
862962001131	HMMPfam hit to PF01751, Toprim domain, score 0.00042
862962001132	PS00177 DNA topoisomerase II signature.
862962001133	HMMPfam hit to PF00204, DNA gyrase B, score 3.4e-79
862962001134	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 2.5e-29
862962001135	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
862962001136	HMMPfam hit to PF01649, Ribosomal protein S20, score 3.8e-16
862962001137	Recombination protein O N terminal; Region: RecO_N; pfam11967
862962001138	DNA repair protein RecO; Region: reco; TIGR00613
862962001139	Recombination protein O C terminal; Region: RecO_C; pfam02565
862962001140	HMMPfam hit to PF02565, Recombination protein O, score 0.00045
862962001141	Yqey-like protein; Region: YqeY; pfam09424
862962001142	HMMPfam hit to PF02637, GatB/Yqey domain, score 7.2e-29
862962001143	cell division protein FtsZ; Validated; Region: PRK09330
862962001144	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
862962001145	nucleotide binding site [chemical binding]; other site
862962001146	SulA interaction site; other site
862962001147	HMMPfam hit to PF03953, Tubulin/FtsZ family, C-terminal domain, score 1.4e-07
862962001148	HMMPfam hit to PF00091, Tubulin/FtsZ family, GTPase domain, score 2.4e-76
862962001149	PS01135 FtsZ protein signature 2.
862962001150	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
862962001151	Cell division protein FtsA; Region: FtsA; smart00842
862962001152	Cell division protein FtsA; Region: FtsA; pfam14450
862962001153	HMMPfam hit to PF02491, Cell division protein FtsA, score 2.2e-27
862962001154	HMMPfam hit to PF02491, Cell division protein FtsA, score 1.3e-22
862962001155	1 probable transmembrane helix predicted for BF638R0304 by TMHMM2.0 at aa 5-24
862962001156	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
862962001157	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
862962001158	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962001159	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
862962001160	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 2.8e-24
862962001161	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 2e-43
862962001162	1 probable transmembrane helix predicted for BF638R0305 by TMHMM2.0 at aa 9-28
862962001163	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
862962001164	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
862962001165	active site
862962001166	homodimer interface [polypeptide binding]; other site
862962001167	HMMPfam hit to PF04101, Glycosyltransferase family, score 1e-34
862962001168	HMMPfam hit to PF03033, Glycosyltransferase family, score 6.9e-27
862962001169	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
862962001170	HMMPfam hit to PF01098, Cell cycle protein, score 3e-58
862962001171	10 probable transmembrane helices predicted for BF638R0307 by TMHMM2.0 at aa 13-32, 47-69, 74-96, 111-133, 146-163, 168-185, 190-212, 288-310, 323-345 and 360-382
862962001172	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962001173	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
862962001174	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962001175	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 0.00017
862962001176	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 7.7e-46
862962001177	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
862962001178	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
862962001179	Mg++ binding site [ion binding]; other site
862962001180	putative catalytic motif [active]
862962001181	putative substrate binding site [chemical binding]; other site
862962001182	10 probable transmembrane helices predicted for BF638R0309 by TMHMM2.0 at aa 20-42, 71-93, 98-115, 136-158, 211-233, 240-259, 279-296, 303-325, 329-351 and 400-419
862962001183	HMMPfam hit to PF00953, Glycosyl transferase, score 1.3e-41
862962001184	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
862962001185	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
862962001186	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962001187	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
862962001188	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 1e-26
862962001189	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 2e-51
862962001190	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
862962001191	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
862962001192	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
862962001193	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
862962001194	HMMPfam hit to PF03793, PASTA domain, score 5e-10
862962001195	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 4.5e-42
862962001196	Signal peptide predicted for BF638R0311 by SignalP 2.0 HMM (Signal peptide probability 0.965) with cleavage site probability 0.558 between residues 29 and 30
862962001197	1 probable transmembrane helix predicted for BF638R0312 by TMHMM2.0 at aa 34-51
862962001198	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
862962001199	MraW methylase family; Region: Methyltransf_5; cl17771
862962001200	HMMPfam hit to PF01795, MraW methylase family, score 6.5e-122
862962001201	cell division protein MraZ; Reviewed; Region: PRK00326
862962001202	MraZ protein; Region: MraZ; pfam02381
862962001203	MraZ protein; Region: MraZ; pfam02381
862962001204	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962001205	Signal peptide predicted for BF638R0317 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.908 between residues 30 and 31
862962001206	PS00018 EF-hand calcium-binding domain.
862962001207	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001208	1 probable transmembrane helix predicted for BF638R0320 by TMHMM2.0 at aa 21-43
862962001209	Signal peptide predicted for BF638R0321 by SignalP 2.0 HMM (Signal peptide probability 0.638) with cleavage site probability 0.433 between residues 17 and 18
862962001210	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962001211	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962001212	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962001213	DNA binding residues [nucleotide binding]
862962001214	HMMPfam hit to PF04542, Sigma-70 region, score 8.2e-13
862962001215	Signal peptide predicted for BF638R0323 by SignalP 2.0 HMM (Signal peptide probability 0.846) with cleavage site probability 0.505 between residues 27 and 28
862962001216	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
862962001217	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962001218	Signal peptide predicted for BF638R0324 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 21 and 22
862962001219	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-09
862962001220	HMMPfam hit to PF00593, TonB dependent receptor, score 1e-21
862962001221	Signal peptide predicted for BF638R0325 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.571 between residues 24 and 25
862962001222	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
862962001223	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
862962001224	putative acyl-acceptor binding pocket; other site
862962001225	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
862962001226	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
862962001227	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
862962001228	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
862962001229	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
862962001230	trimer interface [polypeptide binding]; other site
862962001231	active site
862962001232	HMMPfam hit to PF00692, dUTPase, score 7e-33
862962001233	Signal peptide predicted for BF638R0330 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.686 between residues 33 and 34
862962001234	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962001235	binding surface
862962001236	TPR motif; other site
862962001237	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962001238	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962001239	binding surface
862962001240	TPR motif; other site
862962001241	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962001242	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962001243	TPR motif; other site
862962001244	binding surface
862962001245	TPR repeat; Region: TPR_11; pfam13414
862962001246	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962001247	binding surface
862962001248	TPR motif; other site
862962001249	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962001250	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0032
862962001251	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 7.1e-05
862962001252	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0052
862962001253	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.025
862962001254	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.026
862962001255	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
862962001256	Signal peptide predicted for BF638R0331 by SignalP 2.0 HMM (Signal peptide probability 0.921) with cleavage site probability 0.429 between residues 36 and 37
862962001257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001258	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
862962001259	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962001260	Signal peptide predicted for BF638R0332 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.813 between residues 20 and 21
862962001261	HMMPfam hit to PF01551, Peptidase family M23, score 1.3e-14
862962001262	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962001263	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962001264	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001266	dimer interface [polypeptide binding]; other site
862962001267	phosphorylation site [posttranslational modification]
862962001268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001269	ATP binding site [chemical binding]; other site
862962001270	Mg2+ binding site [ion binding]; other site
862962001271	G-X-G motif; other site
862962001272	Response regulator receiver domain; Region: Response_reg; pfam00072
862962001273	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962001274	active site
862962001275	phosphorylation site [posttranslational modification]
862962001276	intermolecular recognition site; other site
862962001277	dimerization interface [polypeptide binding]; other site
862962001278	Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases; Region: HR1; cl00087
862962001279	Mga helix-turn-helix domain; Region: Mga; pfam05043
862962001280	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962001281	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962001282	Signal peptide predicted for BF638R0333 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.549 between residues 20 and 21
862962001283	HMMPfam hit to PF07494, Two component regulator propeller, score 0.047
862962001284	HMMPfam hit to PF07494, Two component regulator propeller, score 0.55
862962001285	HMMPfam hit to PF07494, Two component regulator propeller, score 0.43
862962001286	HMMPfam hit to PF07495, Two component regulator three Y motif, score 1.8e-18
862962001287	1 probable transmembrane helix predicted for BF638R0333 by TMHMM2.0 at aa 778-800
862962001288	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.3e-15
862962001289	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.6e-33
862962001290	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.3e-33
862962001291	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 5.7e-08
862962001292	PS00041 Bacterial regulatory proteins, araC family signature.
862962001293	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 9.6e-06
862962001294	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
862962001295	active site
862962001296	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 4.1e-38
862962001297	Signal peptide predicted for BF638R0334 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.537 between residues 21 and 22
862962001298	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962001299	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
862962001300	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
862962001301	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962001302	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 4.4e-67
862962001303	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 1.2e-102
862962001304	PS00775 Glycosyl hydrolases family 3 active site.
862962001305	Cluster glycosylhydrolases
862962001306	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; pfam03663
862962001307	HMMPfam hit to PF03663, Glycosyl hydrolase family, score 5e-07
862962001308	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962001309	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962001310	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962001311	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 1.3e-05
862962001312	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 3.3e-09
862962001313	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962001314	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1.2e-30
862962001315	Signal peptide predicted for BF638R0337 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.978 between residues 32 and 33
862962001316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
862962001317	HMMPfam hit to PF07944, Protein of unknown function (DUF1680), score 6.5e-29
862962001318	Signal peptide predicted for BF638R0338 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.672 between residues 27 and 28
862962001319	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
862962001320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
862962001321	HMMPfam hit to PF07944, Protein of unknown function (DUF1680), score 1.4e-224
862962001322	Signal peptide predicted for BF638R0339 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.349 between residues 27 and 28
862962001323	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
862962001324	active site
862962001325	Signal peptide predicted for BF638R0340 by SignalP 2.0 HMM (Signal peptide probability 0.964) with cleavage site probability 0.560 between residues 24 and 25
862962001326	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 1.5e-46
862962001327	Signal peptide predicted for BF638R0341 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 23 and 24
862962001328	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962001329	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962001330	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962001331	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1e-43
862962001332	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 3.4e-06
862962001333	Domain of unknown function (DUF1793); Region: DUF1793; pfam08760
862962001334	Signal peptide predicted for BF638R0342 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.988 between residues 19 and 20
862962001335	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001336	MG2 domain; Region: A2M_N; pfam01835
862962001337	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001338	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.1e-05
862962001339	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001340	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
862962001341	active site
862962001342	catalytic site [active]
862962001343	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
862962001344	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
862962001345	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962001346	HMMPfam hit to PF00754, F5/8 type C domain, score 7.7e-15
862962001347	HMMPfam hit to PF07748, Glycosyl hydrolases family, score 3.1e-59
862962001348	HMMPfam hit to PF01074, Glycosyl hydrolases family, score 6.8e-29
862962001349	Signal peptide predicted for BF638R0344 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.830 between residues 21 and 22
862962001350	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001351	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001352	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001353	PS00430 TonB-dependent receptor proteins signature 1.
862962001354	Signal peptide predicted for BF638R0345 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.813 between residues 36 and 37
862962001355	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1e-15
862962001356	HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-16
862962001357	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962001358	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962001359	SusD family; Region: SusD; pfam07980
862962001360	Signal peptide predicted for BF638R0346 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.640 between residues 25 and 26
862962001361	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001362	Protein of unknown function (DUF3823); Region: DUF3823; pfam12866
862962001363	Signal peptide predicted for BF638R0347 by SignalP 2.0 HMM (Signal peptide probability 0.927) with cleavage site probability 0.692 between residues 55 and 56
862962001364	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001365	Signal peptide predicted for BF638R0348 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 22 and 23
862962001366	Glycosyl hydrolase family 43; Region: GH43_ABN_2; cd08999
862962001367	putative substrate binding site [chemical binding]; other site
862962001368	active site
862962001369	Signal peptide predicted for BF638R0349 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.908 between residues 20 and 21
862962001370	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 3.1e-116
862962001371	Repeat Unit in BF9343
862962001372	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; pfam03663
862962001373	Signal peptide predicted for BF638R0352 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.966 between residues 22 and 23
862962001374	HMMPfam hit to PF03663, Glycosyl hydrolase family, score 1.5e-09
862962001375	Signal peptide predicted for BF638R0353 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.876 between residues 20 and 21
862962001376	Domain of unknown function (DUF1793); Region: DUF1793; pfam08760
862962001377	Signal peptide predicted for BF638R0354 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.645 between residues 31 and 32
862962001378	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962001379	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962001380	Signal peptide predicted for BF638R0355 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.792 between residues 43 and 44
862962001381	Uncharacterized conserved protein [Function unknown]; Region: COG3538
862962001382	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
862962001383	Signal peptide predicted for BF638R0356 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.768 between residues 27 and 28
862962001384	HMMPfam hit to PF06824, Protein of unknown function (DUF1237), score 5.4e-286
862962001385	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
862962001386	active site
862962001387	catalytic residues [active]
862962001388	HMMPfam hit to PF01263, Aldose 1-epimerase, score 1.1e-119
862962001389	PS00545 Aldose 1-epimerase putative active site.
862962001390	Predicted membrane protein [Function unknown]; Region: COG2311
862962001391	Protein of unknown function (DUF418); Region: DUF418; pfam04235
862962001392	HMMPfam hit to PF04171, Protein of unknown function (DUF405), score 5.8e-16
862962001393	8 probable transmembrane helices predicted for BF638R0358 by TMHMM2.0 at aa 60-82, 102-134, 141-163, 219-238, 250-272, 292-309, 321-343 and 353-375
862962001394	HMMPfam hit to PF04235, Protein of unknown function (DUF418), score 5.3e-16
862962001395	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
862962001396	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
862962001397	active site
862962001398	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962001399	sugar binding site [chemical binding]; other site
862962001400	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
862962001401	metal binding site [ion binding]; metal-binding site
862962001402	ligand binding site [chemical binding]; other site
862962001403	Signal peptide predicted for BF638R0359 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.965 between residues 32 and 33
862962001404	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 6.6e-10
862962001405	HMMPfam hit to PF00754, F5/8 type C domain, score 2.1e-08
862962001406	HMMPfam hit to PF03422, Carbohydrate binding module (family 6), score 5.3e-29
862962001407	Signal peptide predicted for BF638R0360 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.863 between residues 34 and 35
862962001408	Glycosyl hydrolase family 43; Region: GH43_bXyl_2; cd08991
862962001409	active site
862962001410	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 6.2e-44
862962001411	Signal peptide predicted for BF638R0361 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.417 between residues 19 and 20
862962001412	Signal peptide predicted for BF638R0362 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.451 between residues 20 and 21
862962001413	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001414	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
862962001415	Signal peptide predicted for BF638R0366 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.311 between residues 24 and 25
862962001416	Signal peptide predicted for BF638R0367 by SignalP 2.0 HMM (Signal peptide probability 0.952) with cleavage site probability 0.324 between residues 22 and 23
862962001417	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001418	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
862962001419	HMMPfam hit to PF01757, Acyltransferase family, score 2e-13
862962001420	11 probable transmembrane helices predicted for BF638R0369 by TMHMM2.0 at aa 24-43, 50-72, 92-114, 121-143, 158-177, 184-206, 216-238, 250-267, 277-296, 316-335 and 345-367
862962001421	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962001422	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962001423	ligand binding site [chemical binding]; other site
862962001424	flexible hinge region; other site
862962001425	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 2.4e-06
862962001426	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962001427	Signal peptide predicted for BF638R0371 by SignalP 2.0 HMM (Signal peptide probability 0.808) with cleavage site probability 0.423 between residues 24 and 25
862962001428	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
862962001429	DNA-binding site [nucleotide binding]; DNA binding site
862962001430	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
862962001431	Transcriptional regulators [Transcription]; Region: PurR; COG1609
862962001432	putative dimerization interface [polypeptide binding]; other site
862962001433	putative ligand binding site [chemical binding]; other site
862962001434	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
862962001435	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
862962001436	Signal peptide predicted for BF638R0373 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.836 between residues 22 and 23
862962001437	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
862962001438	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
862962001439	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
862962001440	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; smart00813
862962001441	Signal peptide predicted for BF638R0374 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.509 between residues 47 and 48
862962001442	HMMPfam hit to PF06964, Alpha-L-arabinofuranosidase C-terminus, score 3.4e-06
862962001443	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
862962001444	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
862962001445	Signal peptide predicted for BF638R0375 by SignalP 2.0 HMM (Signal peptide probability 0.633) with cleavage site probability 0.403 between residues 20 and 21
862962001446	HMMPfam hit to PF05592, Bacterial alpha-L-rhamnosidase, score 3.1e-183
862962001447	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
862962001448	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
862962001449	metal binding site [ion binding]; metal-binding site
862962001450	dimer interface [polypeptide binding]; other site
862962001451	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 3.7e-19
862962001452	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
862962001453	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
862962001454	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
862962001455	acyl-activating enzyme (AAE) consensus motif; other site
862962001456	putative AMP binding site [chemical binding]; other site
862962001457	putative active site [active]
862962001458	putative CoA binding site [chemical binding]; other site
862962001459	HMMPfam hit to PF00501, AMP-binding enzyme, score 3.7e-69
862962001460	PS00455 Putative AMP-binding domain signature.
862962001461	This domain is found in peptide chain release factors; Region: PCRF; smart00937
862962001462	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
862962001463	RF-1 domain; Region: RF-1; pfam00472
862962001464	HMMPfam hit to PF03462, PCRF domain, score 5.8e-37
862962001465	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 2e-37
862962001466	1 probable transmembrane helix predicted for BF638R0379 by TMHMM2.0 at aa 21-43
862962001467	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
862962001468	Signal peptide predicted for BF638R0380 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.987 between residues 22 and 23
862962001469	HMMPfam hit to PF07396, Phosphate-selective porin O and P, score 9.7e-40
862962001470	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001471	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
862962001472	putative active site [active]
862962001473	putative metal binding residues [ion binding]; other site
862962001474	signature motif; other site
862962001475	putative dimer interface [polypeptide binding]; other site
862962001476	putative phosphate binding site [ion binding]; other site
862962001477	HMMPfam hit to PF01928, CYTH domain, score 1.3e-16
862962001478	Predicted membrane protein [Function unknown]; Region: COG3174
862962001479	Domain of unknown function (DUF4010); Region: DUF4010; pfam13194
862962001480	14 probable transmembrane helices predicted for BF638R0382 by TMHMM2.0 at aa 5-27, 40-62, 67-87, 92-114, 119-138, 151-168, 178-200, 207-229, 244-266, 273-292, 319-341, 348-370, 374-396 and 408-430
862962001481	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001482	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962001483	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962001484	Signal peptide predicted for BF638R0383 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.872 between residues 23 and 24
862962001485	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.6e-15
862962001486	HMMPfam hit to PF00593, TonB dependent receptor, score 2.5e-19
862962001487	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
862962001488	Signal peptide predicted for BF638R0384 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.837 between residues 24 and 25
862962001489	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962001490	beta-D-glucuronidase; Provisional; Region: PRK10150
862962001491	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962001492	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962001493	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 7.8e-13
862962001494	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 0.00028
862962001495	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.7e-51
862962001496	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962001497	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962001498	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962001499	active site
862962001500	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 2.3e-137
862962001501	Signal peptide predicted for BF638R0386 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.788 between residues 33 and 34
862962001502	Sulfatase; Region: Sulfatase; cl17466
862962001503	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
862962001504	Signal peptide predicted for BF638R0387 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 24 and 25
862962001505	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
862962001506	HMMPfam hit to PF07470, Glycosyl Hydrolase Family, score 5.9e-07
862962001507	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
862962001508	Signal peptide predicted for BF638R0389 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.952 between residues 19 and 20
862962001509	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962001510	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962001511	SusD family; Region: SusD; pfam07980
862962001512	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001513	Signal peptide predicted for BF638R0390 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.942 between residues 22 and 23
862962001514	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001515	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001516	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001517	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962001518	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962001519	HMMPfam hit to PF00593, TonB dependent receptor, score 3.9e-22
862962001520	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-14
862962001521	Signal peptide predicted for BF638R0391 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 32 and 33
862962001522	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001523	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001524	dimer interface [polypeptide binding]; other site
862962001525	phosphorylation site [posttranslational modification]
862962001526	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001527	ATP binding site [chemical binding]; other site
862962001528	Mg2+ binding site [ion binding]; other site
862962001529	G-X-G motif; other site
862962001530	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962001531	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962001532	active site
862962001533	phosphorylation site [posttranslational modification]
862962001534	intermolecular recognition site; other site
862962001535	dimerization interface [polypeptide binding]; other site
862962001536	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962001537	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962001538	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-15
862962001539	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.4e-37
862962001540	HMMPfam hit to PF00072, Response regulator receiver domain, score 3.8e-27
862962001541	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 3.9e-06
862962001542	PS00041 Bacterial regulatory proteins, araC family signature.
862962001543	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 5.3e-13
862962001544	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962001545	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962001546	2 probable transmembrane helices predicted for BF638R0393 by TMHMM2.0 at aa 7-24 and 760-782
862962001547	HMMPfam hit to PF07495, Two component regulator three Y motif, score 4.2e-08
862962001548	HMMPfam hit to PF07494, Two component regulator propeller, score 0.007
862962001549	HMMPfam hit to PF07494, Two component regulator propeller, score 0.043
862962001550	HMMPfam hit to PF07494, Two component regulator propeller, score 0.023
862962001551	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_7; cd04502
862962001552	active site
862962001553	catalytic triad [active]
862962001554	oxyanion hole [active]
862962001555	Signal peptide predicted for BF638R0394 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 23 and 24
862962001556	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
862962001557	Putative glucoamylase; Region: Glycoamylase; pfam10091
862962001558	Signal peptide predicted for BF638R0395 by SignalP 2.0 HMM (Signal peptide probability 0.698) with cleavage site probability 0.291 between residues 24 and 25
862962001559	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
862962001560	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962001561	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962001562	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 7.2e-94
862962001563	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 4.1e-108
862962001564	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962001565	Signal peptide predicted for BF638R0396 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.988 between residues 21 and 22
862962001566	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962001567	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962001568	Signal peptide predicted for BF638R0397 by SignalP 2.0 HMM (Signal peptide probability 0.828) with cleavage site probability 0.317 between residues 23 and 24
862962001569	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001570	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001571	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001572	HMMPfam hit to PF00593, TonB dependent receptor, score 1.9e-14
862962001573	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001574	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.3e-21
862962001575	Signal peptide predicted for BF638R0398 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 49 and 50
862962001576	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962001577	non-specific DNA binding site [nucleotide binding]; other site
862962001578	salt bridge; other site
862962001579	sequence-specific DNA binding site [nucleotide binding]; other site
862962001580	HMMPfam hit to PF01381, Helix-turn-helix, score 1.4e-06
862962001581	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
862962001582	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
862962001583	Repeat Units in BF9343
862962001584	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001585	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001586	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001587	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962001588	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962001589	Signal peptide predicted for BF638R0406 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.958 between residues 21 and 22
862962001590	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.6e-19
862962001591	HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-24
862962001592	PS00154 E1-E2 ATPases phosphorylation site.
862962001593	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962001594	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962001595	Signal peptide predicted for BF638R0407 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.598 between residues 21 and 22
862962001596	Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563
862962001597	active site triad [active]
862962001598	HMMPfam hit to PF03572, Peptidase family S41, score 4.4e-36
862962001599	Protein of unknown function (DUF3316); Region: DUF3316; pfam11777
862962001600	Signal peptide predicted for BF638R0409 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.901 between residues 21 and 22
862962001601	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
862962001602	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
862962001603	CAP-like domain; other site
862962001604	active site
862962001605	primary dimer interface [polypeptide binding]; other site
862962001606	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 8.9e-57
862962001607	glycyl-tRNA synthetase; Provisional; Region: PRK04173
862962001608	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
862962001609	motif 1; other site
862962001610	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
862962001611	active site
862962001612	motif 2; other site
862962001613	motif 3; other site
862962001614	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
862962001615	anticodon binding site; other site
862962001616	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.6e-53
862962001617	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962001618	HMMPfam hit to PF03129, Anticodon binding domain, score 1.2e-21
862962001619	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
862962001620	Signal peptide predicted for BF638R0412 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.365 between residues 19 and 20
862962001621	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 1.5e-19
862962001622	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
862962001623	Signal peptide predicted for BF638R0413 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.668 between residues 18 and 19
862962001624	Signal peptide predicted for BF638R0414 by SignalP 2.0 HMM (Signal peptide probability 0.936) with cleavage site probability 0.927 between residues 44 and 45
862962001625	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962001626	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962001627	binding surface
862962001628	TPR motif; other site
862962001629	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962001630	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962001631	2 probable transmembrane helices predicted for BF638R0415 by TMHMM2.0 at aa 4-21 and 360-379
862962001632	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
862962001633	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
862962001634	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
862962001635	1 probable transmembrane helix predicted for BF638R0417 by TMHMM2.0 at aa 16-38
862962001636	PS00190 Cytochrome c family heme-binding site signature.
862962001637	PS00190 Cytochrome c family heme-binding site signature.
862962001638	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
862962001639	2 probable transmembrane helices predicted for BF638R0419 by TMHMM2.0 at aa 12-29 and 34-52
862962001640	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
862962001641	1 probable transmembrane helix predicted for BF638R0421 by TMHMM2.0 at aa 38-60
862962001642	Signal peptide predicted for BF638R0422 by SignalP 2.0 HMM (Signal peptide probability 0.841) with cleavage site probability 0.769 between residues 30 and 31
862962001643	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962001644	SusD family; Region: SusD; pfam07980
862962001645	PS00216 Sugar transport proteins signature 1.
862962001646	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001647	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001648	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001649	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962001650	HMMPfam hit to PF00593, TonB dependent receptor, score 4.4e-11
862962001651	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962001652	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2e-18
862962001653	Signal peptide predicted for BF638R0424 by SignalP 2.0 HMM (Signal peptide probability 0.781) with cleavage site probability 0.278 between residues 36 and 37
862962001654	Two component regulator propeller; Region: Reg_prop; pfam07494
862962001655	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962001656	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001657	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001658	dimer interface [polypeptide binding]; other site
862962001659	phosphorylation site [posttranslational modification]
862962001660	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001661	ATP binding site [chemical binding]; other site
862962001662	Mg2+ binding site [ion binding]; other site
862962001663	G-X-G motif; other site
862962001664	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962001665	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962001666	active site
862962001667	phosphorylation site [posttranslational modification]
862962001668	intermolecular recognition site; other site
862962001669	dimerization interface [polypeptide binding]; other site
862962001670	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962001671	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962001672	Signal peptide predicted for BF638R0425 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.957 between residues 22 and 23
862962001673	HMMPfam hit to PF07494, Two component regulator propeller, score 0.0047
862962001674	HMMPfam hit to PF07494, Two component regulator propeller, score 2.4
862962001675	HMMPfam hit to PF07494, Two component regulator propeller, score 0.91
862962001676	HMMPfam hit to PF07494, Two component regulator propeller, score 0.066
862962001677	HMMPfam hit to PF07494, Two component regulator propeller, score 46
862962001678	HMMPfam hit to PF07494, Two component regulator propeller, score 0.0088
862962001679	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962001680	HMMPfam hit to PF07495, Two component regulator three Y motif, score 2.2e-09
862962001681	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.4e-09
862962001682	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2e-30
862962001683	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.6e-27
862962001684	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.001
862962001685	PS00041 Bacterial regulatory proteins, araC family signature.
862962001686	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 8.4e-09
862962001687	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
862962001688	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
862962001689	HMMPfam hit to PF03264, NapC/NirT cytochrome c family, N-termin, score 6.4e-12
862962001690	PS00190 Cytochrome c family heme-binding site signature.
862962001691	PS00190 Cytochrome c family heme-binding site signature.
862962001692	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
862962001693	Signal peptide predicted for BF638R0428 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.206 between residues 35 and 36
862962001694	HMMPfam hit to PF02335, Cytochrome c552, score 6.2e-204
862962001695	PS00190 Cytochrome c family heme-binding site signature.
862962001696	ResB-like family; Region: ResB; pfam05140
862962001697	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
862962001698	6 probable transmembrane helices predicted for BF638R0429 by TMHMM2.0 at aa 12-29, 39-61, 74-93, 113-135, 148-167 and 383-405
862962001699	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
862962001700	8 probable transmembrane helices predicted for BF638R0430 by TMHMM2.0 at aa 5-24, 31-53, 68-85, 90-109, 129-151, 168-187, 202-220 and 227-249
862962001701	HMMPfam hit to PF01578, Cytochrome C assembly protein, score 1.2e-24
862962001702	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
862962001703	Signal peptide predicted for BF638R0431 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21
862962001704	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001705	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962001706	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962001707	ligand binding site [chemical binding]; other site
862962001708	flexible hinge region; other site
862962001709	putative switch regulator; other site
862962001710	non-specific DNA interactions [nucleotide binding]; other site
862962001711	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
862962001712	DNA binding site [nucleotide binding]
862962001713	sequence specific DNA binding site [nucleotide binding]; other site
862962001714	putative cAMP binding site [chemical binding]; other site
862962001715	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 0.00091
862962001716	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
862962001717	Beta-lactamase; Region: Beta-lactamase; cl17358
862962001718	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
862962001719	active site
862962001720	catalytic triad [active]
862962001721	oxyanion hole [active]
862962001722	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1e-07
862962001723	HMMPfam hit to PF00144, Beta-lactamase, score 4.9e-62
862962001724	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
862962001725	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
862962001726	putative active site [active]
862962001727	HMMPfam hit to PF01380, SIS domain, score 0.00012
862962001728	PS01272 Glucokinase regulatory protein family signature.
862962001729	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
862962001730	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
862962001731	10 probable transmembrane helices predicted for BF638R0436 by TMHMM2.0 at aa 13-35, 45-67, 88-110, 132-154, 159-181, 212-234, 246-265, 275-294, 315-337 and 357-379
862962001732	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
862962001733	FAD binding domain; Region: FAD_binding_4; pfam01565
862962001734	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
862962001735	HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 2.5e-53
862962001736	HMMPfam hit to PF01565, FAD binding domain, score 7.9e-34
862962001737	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
862962001738	Signal peptide predicted for BF638R0438 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.791 between residues 26 and 27
862962001739	muropeptide transporter; Reviewed; Region: ampG; PRK11902
862962001740	muropeptide transporter; Validated; Region: ampG; cl17669
862962001741	12 probable transmembrane helices predicted for BF638R0439 by TMHMM2.0 at aa 12-34, 44-61, 73-95, 105-127, 134-156, 171-190, 203-225, 273-295, 302-320, 335-357, 364-386 and 396-414
862962001742	Stage II sporulation protein; Region: SpoIID; pfam08486
862962001743	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
862962001744	GDP-L-galactose-hexose-1-phosphate guanyltransferase; Provisional; Region: PLN03103
862962001745	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962001746	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962001747	active site
862962001748	HMMPfam hit to PF00535, Glycosyl transferase, score 6.2e-23
862962001749	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
862962001750	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962001751	active site
862962001752	metal binding site [ion binding]; metal-binding site
862962001753	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
862962001754	Trp docking motif [polypeptide binding]; other site
862962001755	PQQ-like domain; Region: PQQ_2; pfam13360
862962001756	active site
862962001757	HMMPfam hit to PF01011, PQQ enzyme repeat, score 3.2e-06
862962001758	HMMPfam hit to PF01011, PQQ enzyme repeat, score 1.1e-06
862962001759	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.1e-19
862962001760	Signal peptide predicted for BF638R0443 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.973 between residues 22 and 23
862962001761	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
862962001762	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cl02713
862962001763	active site
862962001764	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962001765	Interdomain contacts; other site
862962001766	Cytokine receptor motif; other site
862962001767	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.0064
862962001768	HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 3.8e-05
862962001769	Signal peptide predicted for BF638R0444 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.657 between residues 23 and 24
862962001770	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
862962001771	Na binding site [ion binding]; other site
862962001772	13 probable transmembrane helices predicted for BF638R0445 by TMHMM2.0 at aa 4-23, 44-66, 76-98, 119-138, 153-170, 182-201, 233-251, 272-294, 314-336, 374-396, 400-422, 429-446 and 456-478
862962001773	HMMPfam hit to PF00474, Sodium:solute symporter family, score 6.6e-07
862962001774	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
862962001775	Signal peptide predicted for BF638R0446 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.923 between residues 31 and 32
862962001776	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962001777	SusD family; Region: SusD; pfam07980
862962001778	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001779	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962001780	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962001781	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962001782	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962001783	Signal peptide predicted for BF638R0448 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.987 between residues 33 and 34
862962001784	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
862962001785	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
862962001786	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
862962001787	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 7.9e-73
862962001788	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 3.9e-47
862962001789	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
862962001790	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
862962001791	The C-terminal domain of a subfamily of Na+ /H+ antiporter existed in bacteria and archea . Na+/H+ exchange proteins eject protons from cells, effectively eliminating excess acid from actively metabolising cells. Na+ /H+ exchange activity is also crucial...; Region: Na_H_Antiporter_C; cd01988
862962001792	Ligand Binding Site [chemical binding]; other site
862962001793	11 probable transmembrane helices predicted for BF638R0451 by TMHMM2.0 at aa 15-37, 96-113, 123-145, 154-176, 186-208, 221-238, 242-261, 273-295, 305-322, 339-361 and 371-390
862962001794	HMMPfam hit to PF00582, Universal stress protein family, score 6.4e-06
862962001795	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
862962001796	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
862962001797	putative ATP binding site [chemical binding]; other site
862962001798	putative substrate interface [chemical binding]; other site
862962001799	HMMPfam hit to PF00899, ThiF family, score 2.9e-42
862962001800	1 probable transmembrane helix predicted for BF638R0452 by TMHMM2.0 at aa 25-47
862962001801	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001802	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962001803	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962001804	Walker A/P-loop; other site
862962001805	ATP binding site [chemical binding]; other site
862962001806	Q-loop/lid; other site
862962001807	ABC transporter signature motif; other site
862962001808	Walker B; other site
862962001809	D-loop; other site
862962001810	H-loop/switch region; other site
862962001811	HMMPfam hit to PF00005, ABC transporter, score 4.3e-59
862962001812	PS00017 ATP/GTP-binding site motif A (P-loop).
862962001813	PS00211 ABC transporters family signature.
862962001814	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
862962001815	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
862962001816	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
862962001817	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.00067
862962001818	1 probable transmembrane helix predicted for BF638R0454 by TMHMM2.0 at aa 15-34
862962001819	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
862962001820	Na2 binding site [ion binding]; other site
862962001821	putative substrate binding site 1 [chemical binding]; other site
862962001822	Na binding site 1 [ion binding]; other site
862962001823	putative substrate binding site 2 [chemical binding]; other site
862962001824	HMMPfam hit to PF00209, Sodium:neurotransmitter symporter family, score 2e-14
862962001825	11 probable transmembrane helices predicted for BF638R0455 by TMHMM2.0 at aa 13-30, 45-67, 95-117, 145-162, 175-197, 217-239, 252-274, 305-327, 348-370, 385-407 and 427-449
862962001826	Predicted integral membrane protein [Function unknown]; Region: COG5652
862962001827	4 probable transmembrane helices predicted for BF638R0456 by TMHMM2.0 at aa 7-24, 39-61, 68-90 and 105-122
862962001828	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
862962001829	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
862962001830	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962001831	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
862962001832	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 6.2e-10
862962001833	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 9e-39
862962001834	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962001835	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962001836	putative substrate translocation pore; other site
862962001837	12 probable transmembrane helices predicted for BF638R0458 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 105-127, 140-162, 167-186, 225-247, 262-284, 291-308, 312-331, 344-366 and 381-398
862962001838	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-33
862962001839	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
862962001840	tyrosine decarboxylase MnfA; Region: tyr_de_CO2_Arch; TIGR03812
862962001841	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962001842	catalytic residue [active]
862962001843	HMMPfam hit to PF00282, Pyridoxal-dependent decarboxylase conse, score 2.5e-64
862962001844	glutaminase; Reviewed; Region: PRK12356
862962001845	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
862962001846	HMMPfam hit to PF04960, Glutaminase, score 1.4e-101
862962001847	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962001848	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962001849	dimer interface [polypeptide binding]; other site
862962001850	phosphorylation site [posttranslational modification]
862962001851	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962001852	ATP binding site [chemical binding]; other site
862962001853	Mg2+ binding site [ion binding]; other site
862962001854	G-X-G motif; other site
862962001855	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.6e-30
862962001856	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.4e-19
862962001857	1 probable transmembrane helix predicted for BF638R0461 by TMHMM2.0 at aa 385-407
862962001858	Signal peptide predicted for BF638R0461 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.939 between residues 25 and 26
862962001859	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
862962001860	dihydropteroate synthase; Region: DHPS; TIGR01496
862962001861	substrate binding pocket [chemical binding]; other site
862962001862	dimer interface [polypeptide binding]; other site
862962001863	inhibitor binding site; inhibition site
862962001864	HMMPfam hit to PF00809, Pterin binding enzyme, score 1.5e-85
862962001865	Uncharacterized conserved protein [Function unknown]; Region: COG1624
862962001866	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
862962001867	2 probable transmembrane helices predicted for BF638R0463 by TMHMM2.0 at aa 10-24 and 31-53
862962001868	HMMPfam hit to PF02457, Domain of unknown function DUF147, score 6.8e-53
862962001869	Repeat Unit in BF9343
862962001870	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
862962001871	2 probable transmembrane helices predicted for BF638R0466 by TMHMM2.0 at aa 4-26 and 198-220
862962001872	NVEALA protein; Region: NVEALA; pfam14055
862962001873	Signal peptide predicted for BF638R0467 by SignalP 2.0 HMM (Signal peptide probability 0.837) with cleavage site probability 0.583 between residues 22 and 23
862962001874	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962001875	NVEALA protein; Region: NVEALA; pfam14055
862962001876	Signal peptide predicted for BF638R0469 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.823 between residues 17 and 18
862962001877	Signal peptide predicted for BF638R0470 by SignalP 2.0 HMM (Signal peptide probability 0.624) with cleavage site probability 0.246 between residues 21 and 22
862962001878	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
862962001879	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
862962001880	NVEALA protein; Region: NVEALA; pfam14055
862962001881	Signal peptide predicted for BF638R0473 by SignalP 2.0 HMM (Signal peptide probability 0.837) with cleavage site probability 0.583 between residues 22 and 23
862962001882	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962001883	NVEALA protein; Region: NVEALA; pfam14055
862962001884	Signal peptide predicted for BF638R0475 by SignalP 2.0 HMM (Signal peptide probability 0.936) with cleavage site probability 0.473 between residues 26 and 27
862962001885	Signal peptide predicted for BF638R0476 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.309 between residues 21 and 22
862962001886	Signal peptide predicted for BF638R0477 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.767 between residues 23 and 24
862962001887	Signal peptide predicted for BF638R0478 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.722 between residues 22 and 23
862962001888	1 probable transmembrane helix predicted for BF638R0479 by TMHMM2.0 at aa 9-31
862962001889	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
862962001890	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
862962001891	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
862962001892	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
862962001893	LrgB-like family; Region: LrgB; pfam04172
862962001894	HMMPfam hit to PF04172, LrgB-like family, score 6.2e-115
862962001895	6 probable transmembrane helices predicted for BF638R0483 by TMHMM2.0 at aa 4-21, 28-46, 61-83, 90-112, 143-165 and 203-225
862962001896	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
862962001897	HMMPfam hit to PF03788, LrgA family, score 1.4e-46
862962001898	4 probable transmembrane helices predicted for BF638R0484 by TMHMM2.0 at aa 13-35, 39-61, 68-90 and 94-116
862962001899	Signal peptide predicted for BF638R0486 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 23 and 24
862962001900	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
862962001901	Signal peptide predicted for BF638R0487 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.938 between residues 23 and 24
862962001902	Signal peptide predicted for BF638R0488 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.971 between residues 24 and 25
862962001903	1 probable transmembrane helix predicted for BF638R0488 by TMHMM2.0 at aa 7-29
862962001904	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
862962001905	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 5.9e-154
862962001906	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
862962001907	propionate/acetate kinase; Provisional; Region: PRK12379
862962001908	HMMPfam hit to PF00871, Acetokinase family, score 1.7e-212
862962001909	PS01075 Acetate and butyrate kinases family signature 1.
862962001910	PS01076 Acetate and butyrate kinases family signature 2.
862962001911	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
862962001912	dimer interface [polypeptide binding]; other site
862962001913	Alkaline phosphatase homologues; Region: alkPPc; smart00098
862962001914	active site
862962001915	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
862962001916	HMMPfam hit to PF00245, Alkaline phosphatase, score 5.4e-35
862962001917	PS00123 Alkaline phosphatase active site.
862962001918	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
862962001919	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
862962001920	putative active site [active]
862962001921	putative metal binding site [ion binding]; other site
862962001922	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.5e-06
862962001923	hypothetical protein; Reviewed; Region: PRK00024
862962001924	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
862962001925	MPN+ (JAMM) motif; other site
862962001926	Zinc-binding site [ion binding]; other site
862962001927	HMMPfam hit to PF04002, RadC, DNA repair protein, score 9.4e-31
862962001928	PS01302 DNA repair protein radC family signature.
862962001929	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
862962001930	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962001931	active site
862962001932	2 probable transmembrane helices predicted for BF638R0495 by TMHMM2.0 at aa 264-286 and 301-323
862962001933	HMMPfam hit to PF00535, Glycosyl transferase, score 1e-33
862962001934	elongation factor P; Validated; Region: PRK00529
862962001935	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
862962001936	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
862962001937	RNA binding site [nucleotide binding]; other site
862962001938	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
862962001939	RNA binding site [nucleotide binding]; other site
862962001940	HMMPfam hit to PF01132, Elongation factor P (EF-P), score 1.9e-118
862962001941	PS01275 Elongation factor P signature.
862962001942	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
862962001943	HMMPfam hit to PF00468, Ribosomal protein L34, score 2.6e-19
862962001944	PS00784 Ribosomal protein L34 signature.
862962001945	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
862962001946	1 probable transmembrane helix predicted for BF638R0498 by TMHMM2.0 at aa 12-34
862962001947	HMMPfam hit to PF03793, PASTA domain, score 2.1e-13
862962001948	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
862962001949	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
862962001950	RNA binding surface [nucleotide binding]; other site
862962001951	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
862962001952	active site
862962001953	HMMPfam hit to PF01479, S4 domain, score 6.7e-07
862962001954	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.1e-64
862962001955	PS01129 Rlu family of pseudouridine synthase signature.
862962001956	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
862962001957	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
862962001958	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962001959	PS00843 D-alanine--D-alanine ligase signature 1.
862962001960	HMMPfam hit to PF07478, D-ala D-ala ligase C-terminus, score 3e-55
862962001961	NigD-like protein; Region: NigD; pfam12667
862962001962	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
862962001963	active site residue [active]
862962001964	HMMPfam hit to PF00581, Rhodanese-like domain, score 1.2e-14
862962001965	N-acetylornithine carbamoyltransferase; Reviewed; Region: PRK04523
862962001966	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
862962001967	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
862962001968	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 5.7e-05
862962001969	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 3.1e-08
862962001970	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
862962001971	Signal peptide predicted for BF638R0505 by SignalP 2.0 HMM (Signal peptide probability 0.970) with cleavage site probability 0.536 between residues 16 and 17
862962001972	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
862962001973	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
862962001974	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
862962001975	putative catalytic cysteine [active]
862962001976	PS01223 Gamma-glutamyl phosphate reductase signature.
862962001977	gamma-glutamyl kinase; Provisional; Region: PRK05429
862962001978	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
862962001979	nucleotide binding site [chemical binding]; other site
862962001980	homotetrameric interface [polypeptide binding]; other site
862962001981	putative phosphate binding site [ion binding]; other site
862962001982	putative allosteric binding site; other site
862962001983	PUA domain; Region: PUA; pfam01472
862962001984	HMMPfam hit to PF01472, PUA domain, score 1.6e-15
862962001985	HMMPfam hit to PF00696, Amino acid kinase family, score 1.3e-42
862962001986	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
862962001987	glutamate racemase; Provisional; Region: PRK00865
862962001988	HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 1.2e-60
862962001989	PS00924 Aspartate and glutamate racemases signature 2.
862962001990	PS00923 Aspartate and glutamate racemases signature 1.
862962001991	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
862962001992	HMMPfam hit to PF03938, Outer membrane protein (OmpH-like), score 3.7e-06
862962001993	Signal peptide predicted for BF638R0511 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 19 and 20
862962001994	periplasmic chaperone; Provisional; Region: PRK10780
862962001995	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
862962001996	HMMPfam hit to PF03938, Outer membrane protein (OmpH-like), score 4.6e-16
862962001997	Signal peptide predicted for BF638R0512 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.987 between residues 20 and 21
862962001998	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
862962001999	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
862962002000	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
862962002001	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
862962002002	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
862962002003	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962002004	HMMPfam hit to PF01103, Surface antigen, score 7.6e-13
862962002005	HMMPfam hit to PF07244, Surface antigen variable number repeat, score 5e-07
862962002006	HMMPfam hit to PF07244, Surface antigen variable number repeat, score 7.7e-05
862962002007	HMMPfam hit to PF07244, Surface antigen variable number repeat, score 9.9e-07
862962002008	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14838
862962002009	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
862962002010	catalytic residue [active]
862962002011	putative FPP diphosphate  binding site; other site
862962002012	putative FPP binding hydrophobic cleft; other site
862962002013	dimer interface [polypeptide binding]; other site
862962002014	putative IPP diphosphate binding site; other site
862962002015	HMMPfam hit to PF01255, Putative undecaprenyl diphosphate syntha, score 1e-106
862962002016	PS01066 Undecaprenyl pyrophosphate synthetase family signature.
862962002017	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
862962002018	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
862962002019	catalytic motif [active]
862962002020	Zn binding site [ion binding]; other site
862962002021	RibD C-terminal domain; Region: RibD_C; pfam01872
862962002022	HMMPfam hit to PF01872, RibD C-terminal domain, score 1.7e-20
862962002023	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase, score 3.4e-34
862962002024	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
862962002025	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
862962002026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962002027	S-adenosylmethionine binding site [chemical binding]; other site
862962002028	PS00092 N-6 Adenine-specific DNA methylases signature.
862962002029	RecX family; Region: RecX; pfam02631
862962002030	HMMPfam hit to PF02631, RecX family, score 0.0012
862962002031	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962002032	active site
862962002033	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.6e-27
862962002034	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
862962002035	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
862962002036	hydrophobic ligand binding site; other site
862962002037	Lyase; Region: Lyase_1; pfam00206
862962002038	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
862962002039	active sites [active]
862962002040	tetramer interface [polypeptide binding]; other site
862962002041	HMMPfam hit to PF00206, Lyase, score 5.4e-42
862962002042	PS00163 Fumarate lyases signature.
862962002043	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
862962002044	Medium-chain acyl-CoA synthetase (MACS) of AAE_MA like; Region: MACS_AAE_MA_like; cd05970
862962002045	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
862962002046	active site
862962002047	acyl-activating enzyme (AAE) consensus motif; other site
862962002048	putative CoA binding site [chemical binding]; other site
862962002049	AMP binding site [chemical binding]; other site
862962002050	HMMPfam hit to PF00501, AMP-binding enzyme, score 6.5e-99
862962002051	PS00455 Putative AMP-binding domain signature.
862962002052	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
862962002053	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962002054	non-specific DNA binding site [nucleotide binding]; other site
862962002055	salt bridge; other site
862962002056	sequence-specific DNA binding site [nucleotide binding]; other site
862962002057	Cupin domain; Region: Cupin_2; pfam07883
862962002058	HMMPfam hit to PF07883, Cupin domain, score 1.7e-17
862962002059	HMMPfam hit to PF01381, Helix-turn-helix, score 3.8e-05
862962002060	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
862962002061	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
862962002062	HMMPfam hit to PF01089, Delta 1-pyrroline-5-carboxylate reductase, score 3.2e-60
862962002063	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002064	acetylornithine aminotransferase; Provisional; Region: PRK02627
862962002065	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
862962002066	inhibitor-cofactor binding pocket; inhibition site
862962002067	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962002068	catalytic residue [active]
862962002069	HMMPfam hit to PF00202, Aminotransferase class-III, score 7.8e-120
862962002070	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
862962002071	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
862962002072	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 4.8e-07
862962002073	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 1.2e-09
862962002074	argininosuccinate synthase; Provisional; Region: PRK13820
862962002075	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
862962002076	Ligand Binding Site [chemical binding]; other site
862962002077	HMMPfam hit to PF00764, Arginosuccinate synthase, score 2.4e-47
862962002078	PS00564 Argininosuccinate synthase signature 1.
862962002079	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
862962002080	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
862962002081	Coenzyme A binding pocket [chemical binding]; other site
862962002082	Arginine repressor [Transcription]; Region: ArgR; COG1438
862962002083	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
862962002084	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
862962002085	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 3.7e-20
862962002086	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 1.1e-19
862962002087	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962002088	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962002089	dimer interface [polypeptide binding]; other site
862962002090	phosphorylation site [posttranslational modification]
862962002091	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962002092	ATP binding site [chemical binding]; other site
862962002093	Mg2+ binding site [ion binding]; other site
862962002094	G-X-G motif; other site
862962002095	1 probable transmembrane helix predicted for BF638R0534 by TMHMM2.0 at aa 2-24
862962002096	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5e-24
862962002097	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3e-34
862962002098	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
862962002099	HMMPfam hit to PF00324, Amino acid permease, score 1.7e-06
862962002100	12 probable transmembrane helices predicted for BF638R0535 by TMHMM2.0 at aa 7-26, 41-63, 84-115, 130-152, 159-181, 204-224, 237-259, 286-308, 339-361, 366-388, 409-431 and 441-463
862962002101	Signal peptide predicted for BF638R0535 by SignalP 2.0 HMM (Signal peptide probability 0.653) with cleavage site probability 0.342 between residues 58 and 59
862962002102	Ion channel; Region: Ion_trans_2; pfam07885
862962002103	7 probable transmembrane helices predicted for BF638R0536 by TMHMM2.0 at aa 51-73, 88-107, 114-136, 146-168, 173-195, 210-229 and 236-258
862962002104	HMMPfam hit to PF07885, Ion channel, score 1.4e-08
862962002105	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
862962002106	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
862962002107	NAD(P) binding site [chemical binding]; other site
862962002108	LDH/MDH dimer interface [polypeptide binding]; other site
862962002109	substrate binding site [chemical binding]; other site
862962002110	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 4.2e-06
862962002111	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 8.2e-25
862962002112	Signal peptide predicted for BF638R0537 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.707 between residues 23 and 24
862962002113	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
862962002114	S1 domain; Region: S1_2; pfam13509
862962002115	Signal peptide predicted for BF638R0539 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.978 between residues 19 and 20
862962002116	SmpA / OmlA family; Region: SmpA_OmlA; cl17115
862962002117	Signal peptide predicted for BF638R0540 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.452 between residues 20 and 21
862962002118	Signal peptide predicted for BF638R0541 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.967 between residues 22 and 23
862962002119	Transglycosylase; Region: Transgly; pfam00912
862962002120	HMMPfam hit to PF00912, Transglycosylase, score 5.3e-78
862962002121	PS00962 Ribosomal protein S2 signature 1.
862962002122	MutS domain III; Region: MutS_III; pfam05192
862962002123	ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283
862962002124	Walker A/P-loop; other site
862962002125	ATP binding site [chemical binding]; other site
862962002126	Q-loop/lid; other site
862962002127	ABC transporter signature motif; other site
862962002128	Walker B; other site
862962002129	D-loop; other site
862962002130	H-loop/switch region; other site
862962002131	HMMPfam hit to PF00488, MutS domain V, score 3.2e-13
862962002132	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002133	Signal peptide predicted for BF638R0545 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 19 and 20
862962002134	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
862962002135	Melibiase; Region: Melibiase; pfam02065
862962002136	HMMPfam hit to PF02065, Melibiase, score 3.4e-151
862962002137	Signal peptide predicted for BF638R0546 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.646 between residues 22 and 23
862962002138	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
862962002139	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
862962002140	putative active site [active]
862962002141	putative catalytic site [active]
862962002142	HMMPfam hit to PF01055, Glycosyl hydrolases family, score 8.9e-68
862962002143	Signal peptide predicted for BF638R0547 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.762 between residues 50 and 51
862962002144	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002145	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002146	SusD family; Region: SusD; pfam07980
862962002147	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002148	Signal peptide predicted for BF638R0548 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.731 between residues 31 and 32
862962002149	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962002150	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002151	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002152	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962002153	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002154	HMMPfam hit to PF00593, TonB dependent receptor, score 4.4e-14
862962002155	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.6e-19
862962002156	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 3.7e-05
862962002157	Signal peptide predicted for BF638R0549 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.917 between residues 45 and 46
862962002158	1 probable transmembrane helix predicted for BF638R0549 by TMHMM2.0 at aa 21-43
862962002159	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962002160	FecR protein; Region: FecR; pfam04773
862962002161	HMMPfam hit to PF04773, FecR protein, score 2.9e-33
862962002162	1 probable transmembrane helix predicted for BF638R0550 by TMHMM2.0 at aa 66-88
862962002163	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962002164	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962002165	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962002166	DNA binding residues [nucleotide binding]
862962002167	HMMPfam hit to PF04542, Sigma-70 region, score 5.5e-07
862962002168	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962002169	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.2e-26
862962002170	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.2e-28
862962002171	Signal peptide predicted for BF638R0553 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.845 between residues 25 and 26
862962002172	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962002173	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962002174	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962002175	Signal peptide predicted for BF638R0554 by SignalP 2.0 HMM (Signal peptide probability 0.929) with cleavage site probability 0.401 between residues 24 and 25
862962002176	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962002177	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962002178	FtsX-like permease family; Region: FtsX; pfam02687
862962002179	HMMPfam hit to PF02687, Predicted permease, score 3e-37
862962002180	4 probable transmembrane helices predicted for BF638R0555 by TMHMM2.0 at aa 25-47, 284-306, 339-361 and 376-398
862962002181	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962002182	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962002183	FtsX-like permease family; Region: FtsX; pfam02687
862962002184	HMMPfam hit to PF02687, Predicted permease, score 4.1e-30
862962002185	4 probable transmembrane helices predicted for BF638R0556 by TMHMM2.0 at aa 20-42, 282-304, 325-347 and 382-404
862962002186	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002187	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962002188	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962002189	Walker A/P-loop; other site
862962002190	ATP binding site [chemical binding]; other site
862962002191	Q-loop/lid; other site
862962002192	ABC transporter signature motif; other site
862962002193	Walker B; other site
862962002194	D-loop; other site
862962002195	H-loop/switch region; other site
862962002196	HMMPfam hit to PF00005, ABC transporter, score 8.5e-52
862962002197	PS00211 ABC transporters family signature.
862962002198	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002199	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
862962002200	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
862962002201	nucleotide binding site [chemical binding]; other site
862962002202	HMMPfam hit to PF00480, ROK family, score 5.1e-42
862962002203	PS01125 ROK family signature.
862962002204	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
862962002205	HMMPfam hit to PF01245, Ribosomal protein L19, score 1.2e-45
862962002206	PS01015 Ribosomal protein L19 signature.
862962002207	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
862962002208	Signal peptide predicted for BF638R0560 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.704 between residues 30 and 31
862962002209	HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 3.7e-26
862962002210	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962002211	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
862962002212	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962002213	active site
862962002214	metal binding site [ion binding]; metal-binding site
862962002215	Signal peptide predicted for BF638R0561 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 33 and 34
862962002216	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 3.4e-16
862962002217	PS00786 5'-nucleotidase signature 2.
862962002218	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
862962002219	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962002220	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
862962002221	Beta-lactamase; Region: Beta-lactamase; cl17358
862962002222	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 3.3e-58
862962002223	PS00775 Glycosyl hydrolases family 3 active site.
862962002224	HMMPfam hit to PF00144, Beta-lactamase, score 5.2e-50
862962002225	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
862962002226	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
862962002227	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
862962002228	Beta-lactamase; Region: Beta-lactamase; cl17358
862962002229	1 probable transmembrane helix predicted for BF638R0563 by TMHMM2.0 at aa 46-65
862962002230	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 1.4e-54
862962002231	HMMPfam hit to PF00144, Beta-lactamase, score 1.3e-50
862962002232	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002233	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002234	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002235	PS00430 TonB-dependent receptor proteins signature 1.
862962002236	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.4e-18
862962002237	HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-11
862962002238	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002239	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962002240	SusD family; Region: SusD; pfam07980
862962002241	Signal peptide predicted for BF638R0565 by SignalP 2.0 HMM (Signal peptide probability 0.965) with cleavage site probability 0.416 between residues 19 and 20
862962002242	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002243	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962002244	Sulfatase; Region: Sulfatase; pfam00884
862962002245	Signal peptide predicted for BF638R0566 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.895 between residues 23 and 24
862962002246	HMMPfam hit to PF00884, Sulfatase, score 6.9e-57
862962002247	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962002248	Signal peptide predicted for BF638R0567 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.909 between residues 27 and 28
862962002249	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
862962002250	Signal peptide predicted for BF638R0568 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.451 between residues 18 and 19
862962002251	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002252	PS-10 peptidase S37; Region: Peptidase_S37; pfam05576
862962002253	1 probable transmembrane helix predicted for BF638R0569 by TMHMM2.0 at aa 59-81
862962002254	HMMPfam hit to PF05576, PS-10 peptidase S37, score 1.2e-12
862962002255	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
862962002256	HMMPfam hit to PF01047, MarR family, score 4.7e-09
862962002257	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
862962002258	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
862962002259	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962002260	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
862962002261	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
862962002262	active site residue [active]
862962002263	SirA_RHOD_Pry_redox.    SirA-like domain located within a multidomain protein of unknown function. Other domains include RHOD (rhodanese homology domain), and Pry_redox (pyridine nucleotide-disulphide oxidoreductase) as well as a C-terminal domain that...; Region: SirA_RHOD_Pry_redox; cd03420
862962002264	CPxP  motif; other site
862962002265	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
862962002266	HMMPfam hit to PF01206, SirA-like protein, score 8.9e-09
862962002267	HMMPfam hit to PF00581, Rhodanese-like domain, score 4.6e-11
862962002268	PS00215 Mitochondrial energy transfer proteins signature.
862962002269	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 8e-13
862962002270	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.1e-81
862962002271	Aspartokinases [Amino acid transport and metabolism]; Region: LysC; COG0527
862962002272	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
862962002273	nucleotide binding site [chemical binding]; other site
862962002274	substrate binding site [chemical binding]; other site
862962002275	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
862962002276	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
862962002277	dimer interface [polypeptide binding]; other site
862962002278	HMMPfam hit to PF00696, Amino acid kinase family, score 0.00011
862962002279	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962002280	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962002281	active site
862962002282	phosphorylation site [posttranslational modification]
862962002283	intermolecular recognition site; other site
862962002284	dimerization interface [polypeptide binding]; other site
862962002285	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962002286	Walker A motif; other site
862962002287	ATP binding site [chemical binding]; other site
862962002288	Walker B motif; other site
862962002289	arginine finger; other site
862962002290	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962002291	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.2e-28
862962002292	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.6e-136
862962002293	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
862962002294	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
862962002295	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 4.5e-14
862962002296	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
862962002297	10 probable transmembrane helices predicted for BF638R0576 by TMHMM2.0 at aa 5-27, 68-90, 128-150, 171-193, 252-274, 281-303, 378-400, 421-443, 495-517 and 537-559
862962002298	HMMPfam hit to PF03814, Potassium-transporting ATPase A subunit, score 3.6e-247
862962002299	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002300	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
862962002301	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
862962002302	Soluble P-type ATPase [General function prediction only]; Region: COG4087
862962002303	7 probable transmembrane helices predicted for BF638R0577 by TMHMM2.0 at aa 35-57, 61-83, 217-239, 254-276, 580-602, 617-636 and 656-678
862962002304	HMMPfam hit to PF00122, E1-E2 ATPase, score 6.4e-58
862962002305	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 7.7e-33
862962002306	PS00154 E1-E2 ATPases phosphorylation site.
862962002307	PS01229 Hypothetical cof family signature 2.
862962002308	PS00018 EF-hand calcium-binding domain.
862962002309	potassium-transporting ATPase subunit C; Provisional; Region: PRK14002
862962002310	HMMPfam hit to PF02669, K+-transporting ATPase, c chain, score 6.3e-56
862962002311	Signal peptide predicted for BF638R0578 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.573 between residues 32 and 33
862962002312	1 probable transmembrane helix predicted for BF638R0578 by TMHMM2.0 at aa 12-34
862962002313	Signal peptide predicted for BF638R0579 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 29 and 30
862962002314	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
862962002315	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
862962002316	Ligand Binding Site [chemical binding]; other site
862962002317	HMMPfam hit to PF02702, Osmosensitive K+ channel His kinase sensor d, score 4.3e-147
862962002318	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
862962002319	dimerization interface [polypeptide binding]; other site
862962002320	PAS domain; Region: PAS; smart00091
862962002321	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
862962002322	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962002323	dimer interface [polypeptide binding]; other site
862962002324	phosphorylation site [posttranslational modification]
862962002325	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962002326	ATP binding site [chemical binding]; other site
862962002327	Mg2+ binding site [ion binding]; other site
862962002328	G-X-G motif; other site
862962002329	2 probable transmembrane helices predicted for BF638R0581 by TMHMM2.0 at aa 7-29 and 49-71
862962002330	HMMPfam hit to PF00672, HAMP domain, score 4.5e-10
862962002331	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.5e-19
862962002332	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.8e-32
862962002333	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962002334	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962002335	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962002336	HMMPfam hit to PF04542, Sigma-70 region, score 3.6e-18
862962002337	FecR protein; Region: FecR; pfam04773
862962002338	1 probable transmembrane helix predicted for BF638R0583 by TMHMM2.0 at aa 90-109
862962002339	HMMPfam hit to PF04773, FecR protein, score 2.9e-26
862962002340	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962002341	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002342	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002343	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002344	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002345	Signal peptide predicted for BF638R0584 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27
862962002346	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 2.7e-08
862962002347	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.7e-22
862962002348	HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-26
862962002349	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002350	Signal peptide predicted for BF638R0585 by SignalP 2.0 HMM (Signal peptide probability 0.910) with cleavage site probability 0.326 between residues 41 and 42
862962002351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002352	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962002353	Signal peptide predicted for BF638R0586 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 24 and 25
862962002354	Signal peptide predicted for BF638R0587 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.991 between residues 18 and 19
862962002355	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002356	NigD-like protein; Region: NigD; pfam12667
862962002357	Lipocalin-like; Region: Lipocalin_3; pfam12702
862962002358	Signal peptide predicted for BF638R0592 by SignalP 2.0 HMM (Signal peptide probability 0.801) with cleavage site probability 0.628 between residues 43 and 44
862962002359	Predicted permeases [General function prediction only]; Region: COG0795
862962002360	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
862962002361	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
862962002362	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
862962002363	HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 1.1e-28
862962002364	6 probable transmembrane helices predicted for BF638R0592 by TMHMM2.0 at aa 20-42, 62-84, 383-402, 406-425, 438-460 and 589-611
862962002365	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
862962002366	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
862962002367	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
862962002368	dimerization interface [polypeptide binding]; other site
862962002369	active site
862962002370	HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate, score 8.8e-110
862962002371	HMMPfam hit to PF00925, GTP cyclohydrolase II, score 8.4e-97
862962002372	aspartate aminotransferase; Provisional; Region: PRK05764
862962002373	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962002374	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962002375	homodimer interface [polypeptide binding]; other site
862962002376	catalytic residue [active]
862962002377	HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.3e-66
862962002378	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
862962002379	Signal peptide predicted for BF638R0595 by SignalP 2.0 HMM (Signal peptide probability 0.644) with cleavage site probability 0.439 between residues 47 and 48
862962002380	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
862962002381	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
862962002382	HMMPfam hit to PF05592, Bacterial alpha-L-rhamnosidase, score 2.1e-225
862962002383	homoserine O-succinyltransferase; Provisional; Region: PRK05368
862962002384	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
862962002385	proposed active site lysine [active]
862962002386	conserved cys residue [active]
862962002387	HMMPfam hit to PF04204, Homoserine O-succinyltransferase, score 8.8e-217
862962002388	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
862962002389	Peptidase family U32; Region: Peptidase_U32; pfam01136
862962002390	Collagenase; Region: DUF3656; pfam12392
862962002391	HMMPfam hit to PF01136, Peptidase family U32, score 2.1e-81
862962002392	PS01276 Peptidase family U32 signature.
862962002393	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002394	6 probable transmembrane helices predicted for BF638R0598 by TMHMM2.0 at aa 7-28, 140-162, 175-197, 217-239, 252-271 and 275-290
862962002395	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962002396	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002397	HMMPfam hit to PF00593, TonB dependent receptor, score 6e-20
862962002398	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.6e-20
862962002399	Signal peptide predicted for BF638R0599 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 34 and 35
862962002400	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962002401	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
862962002402	DNA binding residues [nucleotide binding]
862962002403	dimerization interface [polypeptide binding]; other site
862962002404	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 9.5e-18
862962002405	PS00622 Bacterial regulatory proteins, luxR family signature.
862962002406	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
862962002407	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
862962002408	GxxExxY protein; Region: GxxExxY; TIGR04256
862962002409	DNA repair protein RadA; Provisional; Region: PRK11823
862962002410	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
862962002411	Walker A motif; other site
862962002412	ATP binding site [chemical binding]; other site
862962002413	Walker B motif; other site
862962002414	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
862962002415	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002416	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
862962002417	active site
862962002418	homodimer interface [polypeptide binding]; other site
862962002419	HMMPfam hit to PF00710, Asparaginase, score 3.2e-53
862962002420	PS00917 Asparaginase / glutaminase active site signature 2.
862962002421	PS00144 Asparaginase / glutaminase active site signature 1.
862962002422	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
862962002423	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
862962002424	putative catalytic residues [active]
862962002425	putative nucleotide binding site [chemical binding]; other site
862962002426	putative aspartate binding site [chemical binding]; other site
862962002427	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
862962002428	dimer interface [polypeptide binding]; other site
862962002429	putative threonine allosteric regulatory site; other site
862962002430	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
862962002431	putative threonine allosteric regulatory site; other site
862962002432	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
862962002433	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
862962002434	HMMPfam hit to PF00696, Amino acid kinase family, score 2.1e-32
862962002435	PS00324 Aspartokinase signature.
862962002436	HMMPfam hit to PF01842, ACT domain, score 0.016
862962002437	HMMPfam hit to PF01842, ACT domain, score 8.7e-08
862962002438	HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 8.2e-13
862962002439	HMMPfam hit to PF00742, Homoserine dehydrogenase, score 1.3e-64
862962002440	cofactor-independent phosphoglycerate mutase; Provisional; Region: PRK04200
862962002441	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: PhosphMutase; cl17294
862962002442	HMMPfam hit to PF01676, Metalloenzyme superfamily, score 3.5e-26
862962002443	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
862962002444	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
862962002445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962002446	catalytic residue [active]
862962002447	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 8.7e-24
862962002448	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
862962002449	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
862962002450	EamA-like transporter family; Region: EamA; pfam00892
862962002451	EamA-like transporter family; Region: EamA; pfam00892
862962002452	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 5.2e-20
862962002453	9 probable transmembrane helices predicted for BF638R0608 by TMHMM2.0 at aa 33-55, 68-90, 100-117, 124-142, 152-171, 183-205, 220-242, 249-268 and 273-291
862962002454	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4e-10
862962002455	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962002456	Thiamine pyrophosphokinase; Region: TPK; cd07995
862962002457	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
862962002458	active site
862962002459	dimerization interface [polypeptide binding]; other site
862962002460	thiamine binding site [chemical binding]; other site
862962002461	HMMPfam hit to PF04263, Thiamin pyrophosphokinase, catalytic do, score 5.6e-18
862962002462	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
862962002463	6 probable transmembrane helices predicted for BF638R0610 by TMHMM2.0 at aa 20-42, 46-68, 89-111, 115-134, 141-157 and 161-179
862962002464	HMMPfam hit to PF04973, Nicotinamide mononucleotide transport, score 6.9e-08
862962002465	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962002466	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002467	HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-23
862962002468	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.3e-15
862962002469	Signal peptide predicted for BF638R0611 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.964 between residues 20 and 21
862962002470	Conserved TM helix; Region: TM_helix; pfam05552
862962002471	Mechanosensitive ion channel; Region: MS_channel; pfam00924
862962002472	PS00430 TonB-dependent receptor proteins signature 1.
862962002473	3 probable transmembrane helices predicted for BF638R0612 by TMHMM2.0 at aa 44-66, 89-111 and 126-148
862962002474	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 6.9e-69
862962002475	PS01246 Uncharacterized protein family UPF0003 signature.
862962002476	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962002477	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962002478	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962002479	DNA binding residues [nucleotide binding]
862962002480	HMMPfam hit to PF04542, Sigma-70 region, score 4.2e-16
862962002481	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962002482	FecR protein; Region: FecR; pfam04773
862962002483	1 probable transmembrane helix predicted for BF638R0615 by TMHMM2.0 at aa 85-107
862962002484	HMMPfam hit to PF04773, FecR protein, score 2.5e-25
862962002485	GatB domain; Region: GatB_Yqey; cl17694
862962002486	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962002487	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002488	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002489	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002490	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002491	Signal peptide predicted for BF638R0617 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.650 between residues 26 and 27
862962002492	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 4.5e-10
862962002493	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.4e-21
862962002494	HMMPfam hit to PF00593, TonB dependent receptor, score 1.2e-08
862962002495	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002496	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002497	SusD family; Region: SusD; pfam07980
862962002498	Signal peptide predicted for BF638R0618 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.392 between residues 22 and 23
862962002499	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962002500	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962002501	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962002502	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962002503	Signal peptide predicted for BF638R0619 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 27 and 28
862962002504	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.5e-43
862962002505	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 2.4e-05
862962002506	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 9.8e-18
862962002507	PS00719 Glycosyl hydrolases family 2 signature 1.
862962002508	PS00215 Mitochondrial energy transfer proteins signature.
862962002509	HMMPfam hit to PF00754, F5/8 type C domain, score 9.6e-06
862962002510	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
862962002511	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962002512	Signal peptide predicted for BF638R0620 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.927 between residues 28 and 29
862962002513	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 3.8e-56
862962002514	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 0.00012
862962002515	Signal peptide predicted for BF638R0621 by SignalP 2.0 HMM (Signal peptide probability 0.755) with cleavage site probability 0.531 between residues 28 and 29
862962002516	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
862962002517	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
862962002518	active site
862962002519	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 1.3e-71
862962002520	Domain of unknown function (DUF4374); Region: DUF4374; pfam14298
862962002521	Signal peptide predicted for BF638R0623 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.366 between residues 21 and 22
862962002522	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002523	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962002524	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002525	HMMPfam hit to PF00593, TonB dependent receptor, score 8.8e-07
862962002526	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8e-23
862962002527	Signal peptide predicted for BF638R0624 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 21 and 22
862962002528	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962002529	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962002530	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.34
862962002531	PS00041 Bacterial regulatory proteins, araC family signature.
862962002532	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.5e-07
862962002533	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
862962002534	Domain of unknown function DUF20; Region: UPF0118; pfam01594
862962002535	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 3.1e-39
862962002536	8 probable transmembrane helices predicted for BF638R0629 by TMHMM2.0 at aa 21-38, 43-62, 75-97, 169-191, 232-254, 258-280, 292-314 and 329-360
862962002537	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962002538	thymidine kinase; Provisional; Region: PRK04296
862962002539	HMMPfam hit to PF00265, Thymidine kinase, score 3.4e-72
862962002540	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002541	ribonuclease E; Reviewed; Region: rne; PRK10811
862962002542	Predicted methyltransferases [General function prediction only]; Region: COG0313
862962002543	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
862962002544	putative SAM binding site [chemical binding]; other site
862962002545	putative homodimer interface [polypeptide binding]; other site
862962002546	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.9e-38
862962002547	PS01296 Uncharacterized protein family UPF0011 signature.
862962002548	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
862962002549	Signal peptide predicted for BF638R0633 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.685 between residues 21 and 22
862962002550	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002551	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
862962002552	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962002553	motif II; other site
862962002554	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.2e-20
862962002555	Signal peptide predicted for BF638R0635 by SignalP 2.0 HMM (Signal peptide probability 0.698) with cleavage site probability 0.541 between residues 33 and 34
862962002556	MarC family integral membrane protein; Region: MarC; pfam01914
862962002557	HMMPfam hit to PF01914, MarC family integral membrane protein, score 7e-70
862962002558	6 probable transmembrane helices predicted for BF638R0635 by TMHMM2.0 at aa 21-43, 63-85, 90-107, 127-149, 162-181 and 201-223
862962002559	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002560	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002561	Signal peptide predicted for BF638R0636 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.660 between residues 25 and 26
862962002562	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002563	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002564	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002565	HMMPfam hit to PF00593, TonB dependent receptor, score 5.5e-09
862962002566	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.9e-19
862962002567	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002568	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002569	Signal peptide predicted for BF638R0638 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.713 between residues 26 and 27
862962002570	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002571	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002572	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002573	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002574	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962002575	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002576	HMMPfam hit to PF00593, TonB dependent receptor, score 8.4e-20
862962002577	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.3e-23
862962002578	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962002579	Signal peptide predicted for BF638R0639 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.976 between residues 21 and 22
862962002580	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962002581	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962002582	active site
862962002583	DNA binding site [nucleotide binding]
862962002584	Int/Topo IB signature motif; other site
862962002585	HMMPfam hit to PF00589, Phage integrase family, score 1.6e-15
862962002586	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002587	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002588	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962002589	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002590	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-20
862962002591	PS00107 Protein kinases ATP-binding region signature.
862962002592	HMMPfam hit to PF00593, TonB dependent receptor, score 8.9e-18
862962002593	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002594	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962002595	Signal peptide predicted for BF638R0642 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.771 between residues 24 and 25
862962002596	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962002597	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
862962002598	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
862962002599	HflX GTPase family; Region: HflX; cd01878
862962002600	G1 box; other site
862962002601	GTP/Mg2+ binding site [chemical binding]; other site
862962002602	Switch I region; other site
862962002603	G2 box; other site
862962002604	G3 box; other site
862962002605	Switch II region; other site
862962002606	G4 box; other site
862962002607	G5 box; other site
862962002608	HMMPfam hit to PF01926, GTPase of unknown function, score 9.1e-43
862962002609	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002610	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
862962002611	putative trimer interface [polypeptide binding]; other site
862962002612	putative CoA binding site [chemical binding]; other site
862962002613	PS00583 pfkB family of carbohydrate kinases signature 1.
862962002614	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
862962002615	Peptidase family M1; Region: Peptidase_M1; pfam01433
862962002616	Zn binding site [ion binding]; other site
862962002617	Signal peptide predicted for BF638R0645 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.547 between residues 21 and 22
862962002618	HMMPfam hit to PF01433, Peptidase family M1, score 2.6e-43
862962002619	fumarate hydratase; Provisional; Region: PRK15389
862962002620	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
862962002621	Fumarase C-terminus; Region: Fumerase_C; pfam05683
862962002622	HMMPfam hit to PF05681, Fumarate hydratase (Fumerase), score 1.4e-118
862962002623	HMMPfam hit to PF05683, Fumarase C-terminus, score 6.7e-111
862962002624	PS00163 Fumarate lyases signature.
862962002625	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
862962002626	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962002627	HMMPfam hit to PF01757, Acyltransferase family, score 0.0017
862962002628	10 probable transmembrane helices predicted for BF638R0647 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 153-175, 184-203, 213-235, 242-264, 279-300, 313-332 and 347-369
862962002629	Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain; Region: NAGLU_N; pfam12971
862962002630	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; Region: NAGLU; pfam05089
862962002631	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; Region: NAGLU_C; pfam12972
862962002632	Signal peptide predicted for BF638R0648 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.859 between residues 20 and 21
862962002633	HMMPfam hit to PF05089, Alpha-N-acetylglucosaminidase (NAGLU), score 3.1e-167
862962002634	amino acid transporter; Region: 2A0306; TIGR00909
862962002635	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
862962002636	14 probable transmembrane helices predicted for BF638R0649 by TMHMM2.0 at aa 27-49, 62-84, 104-126, 154-173, 180-202, 228-250, 262-284, 326-345, 376-395, 399-418, 431-453, 457-474, 494-513 and 523-540
862962002637	HMMPfam hit to PF00324, Amino acid permease, score 3e-15
862962002638	Outer membrane efflux protein; Region: OEP; pfam02321
862962002639	Outer membrane efflux protein; Region: OEP; pfam02321
862962002640	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2e-13
862962002641	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.3e-15
862962002642	Signal peptide predicted for BF638R0651 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 19 and 20
862962002643	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962002644	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962002645	12 probable transmembrane helices predicted for BF638R0652 by TMHMM2.0 at aa 12-34, 335-352, 357-379, 389-411, 430-452, 462-484, 525-547, 845-864, 871-893, 898-920, 941-963 and 978-1000
862962002646	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002647	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962002648	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962002649	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962002650	HMMPfam hit to PF00529, HlyD family secretion protein, score 9.7e-10
862962002651	1 probable transmembrane helix predicted for BF638R0653 by TMHMM2.0 at aa 7-24
862962002652	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
862962002653	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
862962002654	lipoyl-biotinyl attachment site [posttranslational modification]; other site
862962002655	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962002656	1 probable transmembrane helix predicted for BF638R0654 by TMHMM2.0 at aa 21-43
862962002657	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
862962002658	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
862962002659	putative active site [active]
862962002660	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962002661	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962002662	Walker A/P-loop; other site
862962002663	ATP binding site [chemical binding]; other site
862962002664	Q-loop/lid; other site
862962002665	ABC transporter signature motif; other site
862962002666	Walker B; other site
862962002667	D-loop; other site
862962002668	H-loop/switch region; other site
862962002669	HMMPfam hit to PF00005, ABC transporter, score 9.6e-55
862962002670	PS00211 ABC transporters family signature.
862962002671	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002672	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 3.7e-09
862962002673	5 probable transmembrane helices predicted for BF638R0655 by TMHMM2.0 at aa 166-188, 198-220, 276-298, 308-325 and 392-414
862962002674	HMMPfam hit to PF03412, Peptidase C39 family, score 5.6e-37
862962002675	CAAX protease self-immunity; Region: Abi; pfam02517
862962002676	8 probable transmembrane helices predicted for BF638R0656 by TMHMM2.0 at aa 5-27, 37-54, 74-93, 108-130, 137-154, 158-175, 180-202 and 212-234
862962002677	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 3.8e-14
862962002678	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962002679	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; pfam02709
862962002680	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962002681	active site
862962002682	GTPase RsgA; Reviewed; Region: PRK00098
862962002683	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
862962002684	RNA binding site [nucleotide binding]; other site
862962002685	homodimer interface [polypeptide binding]; other site
862962002686	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
862962002687	GTPase/Zn-binding domain interface [polypeptide binding]; other site
862962002688	GTP/Mg2+ binding site [chemical binding]; other site
862962002689	G4 box; other site
862962002690	G5 box; other site
862962002691	G1 box; other site
862962002692	Switch I region; other site
862962002693	G2 box; other site
862962002694	G3 box; other site
862962002695	Switch II region; other site
862962002696	HMMPfam hit to PF03193, Protein of unknown function, DUF258, score 1.1e-142
862962002697	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002698	ribosome recycling factor; Reviewed; Region: frr; PRK00083
862962002699	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
862962002700	hinge region; other site
862962002701	HMMPfam hit to PF01765, Ribosome recycling factor, score 1.3e-72
862962002702	Bacterial SH3 domain; Region: SH3_3; pfam08239
862962002703	6 probable transmembrane helices predicted for BF638R0663 by TMHMM2.0 at aa 7-24, 112-129, 142-161, 176-198, 219-241 and 289-311
862962002704	Signal peptide predicted for BF638R0663 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.889 between residues 23 and 24
862962002705	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
862962002706	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
862962002707	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 8.7e-09
862962002708	Signal peptide predicted for BF638R0664 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.400 between residues 35 and 36
862962002709	Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170
862962002710	MreB/Mbl protein; Region: MreB_Mbl; pfam06723
862962002711	nucleotide binding site [chemical binding]; other site
862962002712	putative NEF/HSP70 interaction site [polypeptide binding]; other site
862962002713	SBD interface [polypeptide binding]; other site
862962002714	HMMPfam hit to PF00012, Hsp70 protein, score 4.5e-42
862962002715	PS01036 Heat shock hsp70 proteins family signature 3.
862962002716	PS00329 Heat shock hsp70 proteins family signature 2.
862962002717	PS00297 Heat shock hsp70 proteins family signature 1.
862962002718	Signal peptide predicted for BF638R0668 by SignalP 2.0 HMM (Signal peptide probability 0.939) with cleavage site probability 0.390 between residues 20 and 21
862962002719	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
862962002720	putative nucleotide binding site [chemical binding]; other site
862962002721	uridine monophosphate binding site [chemical binding]; other site
862962002722	homohexameric interface [polypeptide binding]; other site
862962002723	HMMPfam hit to PF00696, Amino acid kinase family, score 2.7e-58
862962002724	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
862962002725	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
862962002726	12 probable transmembrane helices predicted for BF638R0670 by TMHMM2.0 at aa 21-43, 48-70, 91-113, 133-155, 168-190, 194-216, 244-266, 276-298, 318-340, 355-377, 386-403 and 413-432
862962002727	HMMPfam hit to PF01554, MatE, score 1.2e-28
862962002728	Signal peptide predicted for BF638R0672 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.949 between residues 20 and 21
862962002729	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
862962002730	active site
862962002731	catalytic residues [active]
862962002732	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 8e-06
862962002733	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962002734	binding surface
862962002735	TPR motif; other site
862962002736	Signal peptide predicted for BF638R0673 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.547 between residues 23 and 24
862962002737	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.2
862962002738	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.6
862962002739	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962002740	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
862962002741	active site
862962002742	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962002743	Signal peptide predicted for BF638R0674 by SignalP 2.0 HMM (Signal peptide probability 0.914) with cleavage site probability 0.338 between residues 29 and 30
862962002744	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
862962002745	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
862962002746	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 1.5e-31
862962002747	Protein of unknown function (DUF419); Region: DUF419; pfam04237
862962002748	HMMPfam hit to PF04237, Protein of unknown function (DUF419), score 1.5e-27
862962002749	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
862962002750	HMMPfam hit to PF02021, Uncharacterised protein family UPF0102, score 3.6e-10
862962002751	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
862962002752	nucleoside/Zn binding site; other site
862962002753	dimer interface [polypeptide binding]; other site
862962002754	catalytic motif [active]
862962002755	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase, score 1.6e-34
862962002756	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
862962002757	Signal peptide predicted for BF638R0680 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.668 between residues 28 and 29
862962002758	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
862962002759	archaetidylserine synthase; Region: archae_ser_T; TIGR04217
862962002760	5 probable transmembrane helices predicted for BF638R0681 by TMHMM2.0 at aa 35-57, 105-124, 131-153, 163-185 and 198-227
862962002761	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 6.7e-13
862962002762	PS00379 CDP-alcohol phosphatidyltransferases signature.
862962002763	Signal peptide predicted for BF638R0681 by SignalP 2.0 HMM (Signal peptide probability 0.636) with cleavage site probability 0.492 between residues 28 and 29
862962002764	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
862962002765	HMMPfam hit to PF02666, Phosphatidylserine decarboxylase, score 2.7e-26
862962002766	2 probable transmembrane helices predicted for BF638R0682 by TMHMM2.0 at aa 19-38 and 42-64
862962002767	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
862962002768	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
862962002769	active site
862962002770	PHP Thumb interface [polypeptide binding]; other site
862962002771	metal binding site [ion binding]; metal-binding site
862962002772	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
862962002773	generic binding surface II; other site
862962002774	generic binding surface I; other site
862962002775	HMMPfam hit to PF02231, PHP domain N-terminal region, score 2.9e-19
862962002776	HMMPfam hit to PF02811, PHP domain C-terminal region, score 4.9e-31
862962002777	HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 3.1e-228
862962002778	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.5e-06
862962002779	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962002780	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962002781	catalytic residues [active]
862962002782	HMMPfam hit to PF00085, Thioredoxin, score 4.8e-40
862962002783	PS00194 Thioredoxin family active site.
862962002784	RDD family; Region: RDD; pfam06271
862962002785	HMMPfam hit to PF06271, RDD family, score 6.9e-29
862962002786	3 probable transmembrane helices predicted for BF638R0686 by TMHMM2.0 at aa 25-47, 59-81 and 110-132
862962002787	Integral membrane protein DUF95; Region: DUF95; pfam01944
862962002788	6 probable transmembrane helices predicted for BF638R0688 by TMHMM2.0 at aa 100-119, 157-179, 186-203, 223-242, 262-280 and 290-309
862962002789	6 probable transmembrane helices predicted for BF638R0689 by TMHMM2.0 at aa 42-64, 84-106, 136-158, 163-182, 203-225 and 260-282
862962002790	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
862962002791	1 probable transmembrane helix predicted for BF638R0690 by TMHMM2.0 at aa 60-82
862962002792	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
862962002793	2 probable transmembrane helices predicted for BF638R0691 by TMHMM2.0 at aa 7-26 and 280-297
862962002794	MoxR-like ATPases [General function prediction only]; Region: COG0714
862962002795	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962002796	Walker A motif; other site
862962002797	ATP binding site [chemical binding]; other site
862962002798	Walker B motif; other site
862962002799	arginine finger; other site
862962002800	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 4.5e-12
862962002801	HMMPfam hit to PF07726, ATPase family associated with various cellul, score 4.3e-81
862962002802	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
862962002803	Protein of unknown function DUF58; Region: DUF58; pfam01882
862962002804	2 probable transmembrane helices predicted for BF638R0693 by TMHMM2.0 at aa 7-24 and 28-50
862962002805	HMMPfam hit to PF01882, Protein of unknown function DUF58, score 6e-28
862962002806	2 probable transmembrane helices predicted for BF638R0694 by TMHMM2.0 at aa 10-29 and 49-67
862962002807	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
862962002808	HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079, score 1.4e-36
862962002809	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002810	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
862962002811	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
862962002812	ABC-ATPase subunit  interface; other site
862962002813	dimer interface [polypeptide binding]; other site
862962002814	putative PBP binding regions; other site
862962002815	8 probable transmembrane helices predicted for BF638R0696 by TMHMM2.0 at aa 13-32, 47-69, 90-112, 132-154, 166-185, 190-212, 217-239 and 243-265
862962002816	HMMPfam hit to PF00950, ABC 3 transport family, score 7.6e-82
862962002817	PS00118 Phospholipase A2 histidine active site.
862962002818	1 probable transmembrane helix predicted for BF638R0697 by TMHMM2.0 at aa 4-21
862962002819	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
862962002820	Peptidase family M28; Region: Peptidase_M28; pfam04389
862962002821	metal binding site [ion binding]; metal-binding site
862962002822	Signal peptide predicted for BF638R0698 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.793 between residues 20 and 21
862962002823	HMMPfam hit to PF04389, Peptidase family M28, score 7.4e-61
862962002824	Signal peptide predicted for BF638R0699 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.295 between residues 53 and 54
862962002825	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962002826	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962002827	Signal peptide predicted for BF638R0700 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.664 between residues 23 and 24
862962002828	PS00216 Sugar transport proteins signature 1.
862962002829	Galactose oxidase, central domain; Region: Kelch_3; cl02701
862962002830	Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]; Region: COG3947
862962002831	2 probable transmembrane helices predicted for BF638R0701 by TMHMM2.0 at aa 20-42 and 566-588
862962002832	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002833	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002834	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002835	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962002836	Signal peptide predicted for BF638R0703 by SignalP 2.0 HMM (Signal peptide probability 0.889) with cleavage site probability 0.662 between residues 36 and 37
862962002837	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.2e-14
862962002838	HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-14
862962002839	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962002840	SusD family; Region: SusD; pfam07980
862962002841	Signal peptide predicted for BF638R0704 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.698 between residues 22 and 23
862962002842	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
862962002843	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962002844	sugar binding site [chemical binding]; other site
862962002845	Signal peptide predicted for BF638R0705 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.568 between residues 26 and 27
862962002846	HMMPfam hit to PF00754, F5/8 type C domain, score 1.4e-22
862962002847	PS00591 Glycosyl hydrolases family 10 active site.
862962002848	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962002849	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
862962002850	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962002851	Signal peptide predicted for BF638R0706 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.989 between residues 21 and 22
862962002852	HMMPfam hit to PF00754, F5/8 type C domain, score 1.8e-15
862962002853	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962002854	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
862962002855	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962002856	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962002857	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962002858	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
862962002859	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.1e-103
862962002860	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 1.6e-12
862962002861	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 9.1e-104
862962002862	PS00719 Glycosyl hydrolases family 2 signature 1.
862962002863	PS00608 Glycosyl hydrolases family 2 acid/base catalyst.
862962002864	HMMPfam hit to PF02929, Beta galactosidase small chain, N ter, score 1.1e-15
862962002865	PS00152 ATP synthase alpha and beta subunits signature.
862962002866	HMMPfam hit to PF02930, Beta galactosidase small chain, C ter, score 1.3e-19
862962002867	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
862962002868	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
862962002869	hinge; other site
862962002870	active site
862962002871	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 1.8e-69
862962002872	PS00885 EPSP synthase signature 2.
862962002873	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962002874	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002875	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00021
862962002876	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962002877	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962002878	dimer interface [polypeptide binding]; other site
862962002879	phosphorylation site [posttranslational modification]
862962002880	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962002881	ATP binding site [chemical binding]; other site
862962002882	Mg2+ binding site [ion binding]; other site
862962002883	G-X-G motif; other site
862962002884	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.7e-19
862962002885	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.7e-34
862962002886	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962002887	Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)...; Region: GH20_DspB_LnbB-like; cd06564
862962002888	active site
862962002889	Signal peptide predicted for BF638R0711 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.910 between residues 23 and 24
862962002890	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyti, score 6.3e-75
862962002891	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
862962002892	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962002893	HMMPfam hit to PF01757, Acyltransferase family, score 5.5e-05
862962002894	10 probable transmembrane helices predicted for BF638R0712 by TMHMM2.0 at aa 13-32, 52-74, 91-113, 133-155, 168-185, 200-217, 230-252, 262-284, 304-321 and 325-347
862962002895	hypothetical protein; Region: PHA00684
862962002896	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
862962002897	active site
862962002898	dimer interface [polypeptide binding]; other site
862962002899	metal binding site [ion binding]; metal-binding site
862962002900	HMMPfam hit to PF01761, 3-dehydroquinate synthase, score 7.3e-117
862962002901	4 probable transmembrane helices predicted for BF638R0715 by TMHMM2.0 at aa 13-35, 45-67, 86-103 and 107-129
862962002902	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962002903	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002904	Signal peptide predicted for BF638R0716 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.670 between residues 20 and 21
862962002905	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002906	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
862962002907	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
862962002908	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
862962002909	putative active site [active]
862962002910	catalytic site [active]
862962002911	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
862962002912	putative active site [active]
862962002913	catalytic site [active]
862962002914	2 probable transmembrane helices predicted for BF638R0717 by TMHMM2.0 at aa 12-34 and 49-71
862962002915	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 9e-11
862962002916	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 5.8e-06
862962002917	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
862962002918	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962002919	S-adenosylmethionine binding site [chemical binding]; other site
862962002920	HMMPfam hit to PF03602, Conserved hypothetical protein, score 7e-35
862962002921	PS00092 N-6 Adenine-specific DNA methylases signature.
862962002922	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
862962002923	Psb28 protein; Region: Psb28; cl04326
862962002924	1 probable transmembrane helix predicted for BF638R0720 by TMHMM2.0 at aa 7-29
862962002925	AAA domain; Region: AAA_30; pfam13604
862962002926	Family description; Region: UvrD_C_2; pfam13538
862962002927	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002928	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
862962002929	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962002930	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962002931	Signal peptide predicted for BF638R0722 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.518 between residues 25 and 26
862962002932	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962002933	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962002934	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962002935	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962002936	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962002937	HMMPfam hit to PF00593, TonB dependent receptor, score 6.2e-20
862962002938	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.9e-20
862962002939	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 4.9e-09
862962002940	Signal peptide predicted for BF638R0723 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.616 between residues 43 and 44
862962002941	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962002942	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962002943	Signal peptide predicted for BF638R0724 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 19 and 20
862962002944	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962002945	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962002946	Signal peptide predicted for BF638R0725 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.591 between residues 21 and 22
862962002947	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962002948	FecR protein; Region: FecR; pfam04773
862962002949	HMMPfam hit to PF04773, FecR protein, score 1.6e-22
862962002950	1 probable transmembrane helix predicted for BF638R0726 by TMHMM2.0 at aa 97-119
862962002951	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962002952	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962002953	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962002954	DNA binding residues [nucleotide binding]
862962002955	HMMPfam hit to PF04545, Sigma-70, region, score 4.3e-13
862962002956	HMMPfam hit to PF04542, Sigma-70 region, score 3.1e-08
862962002957	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962002958	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962002959	Signal peptide predicted for BF638R0728 by SignalP 2.0 HMM (Signal peptide probability 0.929) with cleavage site probability 0.443 between residues 61 and 62
862962002960	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
862962002961	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962002962	putative substrate translocation pore; other site
862962002963	12 probable transmembrane helices predicted for BF638R0729 by TMHMM2.0 at aa 9-31, 46-68, 75-97, 101-123, 136-158, 163-185, 215-237, 247-269, 276-298, 302-324, 337-359 and 364-386
862962002964	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-37
862962002965	Signal peptide predicted for BF638R0729 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.597 between residues 37 and 38
862962002966	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962002967	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962002968	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.9e-11
862962002969	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
862962002970	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
862962002971	motif 1; other site
862962002972	active site
862962002973	motif 2; other site
862962002974	motif 3; other site
862962002975	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
862962002976	DHHA1 domain; Region: DHHA1; pfam02272
862962002977	HMMPfam hit to PF02272, DHHA1 domain, score 3.7e-10
862962002978	HMMPfam hit to PF01411, tRNA synthetases class II (A), score 0
862962002979	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
862962002980	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962002981	1 probable transmembrane helix predicted for BF638R0732 by TMHMM2.0 at aa 29-51
862962002982	HMMPfam hit to PF01551, Peptidase family M23, score 6.6e-48
862962002983	PS00017 ATP/GTP-binding site motif A (P-loop).
862962002984	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
862962002985	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
862962002986	DNA binding residues [nucleotide binding]
862962002987	HMMPfam hit to PF00376, MerR family regulatory protein, score 4.4e-08
862962002988	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
862962002989	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962002990	Zn2+ binding site [ion binding]; other site
862962002991	Mg2+ binding site [ion binding]; other site
862962002992	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
862962002993	synthetase active site [active]
862962002994	NTP binding site [chemical binding]; other site
862962002995	metal binding site [ion binding]; metal-binding site
862962002996	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
862962002997	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
862962002998	HMMPfam hit to PF01842, ACT domain, score 2.8e-06
862962002999	PS00090 Nitrogenases component 1 alpha and beta subunits signature 2.
862962003000	HMMPfam hit to PF02824, TGS domain, score 4.6e-28
862962003001	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 9.8e-45
862962003002	HMMPfam hit to PF01966, HD domain, score 6.1e-12
862962003003	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
862962003004	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
862962003005	N-acetyl-D-glucosamine binding site [chemical binding]; other site
862962003006	catalytic residue [active]
862962003007	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962003008	HMMPfam hit to PF01476, LysM domain, score 1.1e-15
862962003009	HMMPfam hit to PF01464, Transglycosylase SLT domain, score 1.1e-30
862962003010	PS00922 Prokaryotic transglycosylases signature.
862962003011	Signal peptide predicted for BF638R0736 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.990 between residues 30 and 31
862962003012	3 probable transmembrane helices predicted for BF638R0737 by TMHMM2.0 at aa 7-29, 152-171 and 228-246
862962003013	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
862962003014	ParB-like nuclease domain; Region: ParBc; pfam02195
862962003015	HMMPfam hit to PF02195, ParB-like nuclease domain, score 2e-34
862962003016	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
862962003017	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962003018	P-loop; other site
862962003019	Magnesium ion binding site [ion binding]; other site
862962003020	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962003021	Magnesium ion binding site [ion binding]; other site
862962003022	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.2e-56
862962003023	1 probable transmembrane helix predicted for BF638R0740 by TMHMM2.0 at aa 50-69
862962003024	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
862962003025	HMMPfam hit to PF01975, Survival protein SurE, score 1e-49
862962003026	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
862962003027	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
862962003028	HMMPfam hit to PF02684, Lipid-A-disaccharide synthetase, score 2.8e-65
862962003029	NigD-like protein; Region: NigD; pfam12667
862962003030	Signal peptide predicted for BF638R0743 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.902 between residues 21 and 22
862962003031	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
862962003032	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
862962003033	7 probable transmembrane helices predicted for BF638R0744 by TMHMM2.0 at aa 15-37, 60-82, 86-103, 110-132, 147-169, 190-212 and 261-278
862962003034	HMMPfam hit to PF01148, Cytidylyltransferase family, score 4.1e-54
862962003035	PS01315 Phosphatidate cytidylyltransferase signature.
862962003036	FtsH Extracellular; Region: FtsH_ext; pfam06480
862962003037	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
862962003038	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962003039	Walker A motif; other site
862962003040	ATP binding site [chemical binding]; other site
862962003041	Walker B motif; other site
862962003042	arginine finger; other site
862962003043	Peptidase family M41; Region: Peptidase_M41; pfam01434
862962003044	HMMPfam hit to PF01434, Peptidase family M41, score 5.7e-97
862962003045	HMMPfam hit to PF00004, ATPase family associated with various c, score 2.1e-92
862962003046	PS00674 AAA-protein family signature.
862962003047	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003048	HMMPfam hit to PF06480, FtsH Extracellular, score 1.6e-32
862962003049	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003050	2 probable transmembrane helices predicted for BF638R0745 by TMHMM2.0 at aa 20-42 and 132-154
862962003051	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
862962003052	HMMPfam hit to PF02410, Domain of unknown function DUF143, score 4.7e-27
862962003053	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
862962003054	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
862962003055	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
862962003056	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
862962003057	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
862962003058	HMMPfam hit to PF03993, Domain of Unknown Function (DUF349), score 2.8e-06
862962003059	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
862962003060	MgtE intracellular N domain; Region: MgtE_N; smart00924
862962003061	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
862962003062	Divalent cation transporter; Region: MgtE; pfam01769
862962003063	4 probable transmembrane helices predicted for BF638R0748 by TMHMM2.0 at aa 283-300, 357-379, 386-408 and 423-445
862962003064	HMMPfam hit to PF01769, Divalent cation transporter, score 3.4e-28
862962003065	HMMPfam hit to PF00571, CBS domain, score 3.3e-11
862962003066	HMMPfam hit to PF00571, CBS domain, score 9.6e-05
862962003067	HMMPfam hit to PF03448, MgtE intracellular domain, score 2.7e-44
862962003068	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
862962003069	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
862962003070	HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase, score 1.4e-42
862962003071	PS01131 Ribosomal RNA adenine dimethylases signature.
862962003072	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
862962003073	8 probable transmembrane helices predicted for BF638R0750 by TMHMM2.0 at aa 16-33, 48-67, 137-159, 174-196, 225-247, 252-274, 281-303 and 308-330
862962003074	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
862962003075	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
862962003076	metal binding site [ion binding]; metal-binding site
862962003077	dimer interface [polypeptide binding]; other site
862962003078	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 8.7e-14
862962003079	MG2 domain; Region: A2M_N; pfam01835
862962003080	Signal peptide predicted for BF638R0752 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.991 between residues 19 and 20
862962003081	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
862962003082	Signal peptide predicted for BF638R0753 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.506 between residues 23 and 24
862962003083	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003084	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
862962003085	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962003086	HMMPfam hit to PF00593, TonB dependent receptor, score 3.5e-17
862962003087	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-08
862962003088	Signal peptide predicted for BF638R0754 by SignalP 2.0 HMM (Signal peptide probability 0.729) with cleavage site probability 0.317 between residues 21 and 22
862962003089	MG2 domain; Region: A2M_N; pfam01835
862962003090	Alpha-2-macroglobulin family; Region: A2M; pfam00207
862962003091	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
862962003092	Signal peptide predicted for BF638R0756 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.753 between residues 22 and 23
862962003093	Signal peptide predicted for BF638R0757 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.942 between residues 27 and 28
862962003094	NVEALA protein; Region: NVEALA; pfam14055
862962003095	Signal peptide predicted for BF638R0758 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.555 between residues 27 and 28
862962003096	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
862962003097	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003098	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962003099	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962003100	Signal peptide predicted for BF638R0760 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 33 and 34
862962003101	HMMPfam hit to PF07610, Protein of unknown function (DUF1573), score 5.2e-19
862962003102	PS00052 Ribosomal protein S7 signature.
862962003103	membrane ATPase/protein kinase; Provisional; Region: PRK09435
862962003104	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
862962003105	Walker A; other site
862962003106	HMMPfam hit to PF03308, ArgK protein, score 4.4e-130
862962003107	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003108	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
862962003109	EamA-like transporter family; Region: EamA; pfam00892
862962003110	EamA-like transporter family; Region: EamA; pfam00892
862962003111	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.6e-11
862962003112	9 probable transmembrane helices predicted for BF638R0762 by TMHMM2.0 at aa 21-39, 54-73, 86-108, 113-132, 141-163, 168-188, 195-217, 232-254 and 266-288
862962003113	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.2e-23
862962003115	HMMPfam hit to PF00005, ABC transporter, score 7.9e-07
862962003116	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003117	PS00211 ABC transporters family signature.
862962003118	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
862962003119	Mechanosensitive ion channel; Region: MS_channel; pfam00924
862962003120	5 probable transmembrane helices predicted for BF638R0765 by TMHMM2.0 at aa 25-47, 70-92, 105-127, 140-162 and 167-184
862962003121	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 2.3e-26
862962003122	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962003123	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962003124	PS00041 Bacterial regulatory proteins, araC family signature.
862962003125	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.7e-06
862962003126	PS00041 Bacterial regulatory proteins, araC family signature.
862962003127	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.2e-09
862962003128	HipA-like N-terminal domain; Region: HipA_N; pfam07805
862962003129	HipA-like C-terminal domain; Region: HipA_C; pfam07804
862962003130	HMMPfam hit to PF07804, HipA-like C-terminal domain, score 9.2e-23
862962003131	HipA N-terminal domain; Region: couple_hipA; TIGR03071
862962003132	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962003133	non-specific DNA binding site [nucleotide binding]; other site
862962003134	salt bridge; other site
862962003135	sequence-specific DNA binding site [nucleotide binding]; other site
862962003136	HMMPfam hit to PF01381, Helix-turn-helix, score 7.6e-13
862962003137	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
862962003138	PS00636 Nt-dnaJ domain signature.
862962003139	1 probable transmembrane helix predicted for BF638R0774 by TMHMM2.0 at aa 23-45
862962003140	similar to PS_7/PS_G region lipopolysaccharide biosynthesis locus in BF9343
862962003141	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962003142	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962003143	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 5.8e-49
862962003144	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
862962003145	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
862962003146	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
862962003147	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 1.1e-40
862962003148	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 6.7e-37
862962003149	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 1e-07
862962003150	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962003151	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
862962003152	substrate binding site; other site
862962003153	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.7e-05
862962003154	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
862962003155	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962003156	NAD(P) binding site [chemical binding]; other site
862962003157	active site
862962003158	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
862962003159	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962003160	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962003161	NAD(P) binding site [chemical binding]; other site
862962003162	active site
862962003164	1 probable transmembrane helix predicted for BF638R0783 by TMHMM2.0 at aa 4-23
862962003165	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962003166	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962003167	active site
862962003168	HMMPfam hit to PF00535, Glycosyl transferase, score 4e-30
862962003169	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962003170	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962003171	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1.4e-08
862962003172	13 probable transmembrane helices predicted for BF638R0787 by TMHMM2.0 at aa 15-37, 93-115, 125-147, 154-176, 181-200, 225-247, 257-279, 305-324, 334-356, 368-390, 394-416, 428-447 and 451-473
862962003173	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962003174	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962003175	active site
862962003176	HMMPfam hit to PF00535, Glycosyl transferase, score 7.1e-34
862962003177	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962003178	NAD(P) binding site [chemical binding]; other site
862962003179	active site
862962003180	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
862962003181	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962003182	inhibitor-cofactor binding pocket; inhibition site
862962003183	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962003184	catalytic residue [active]
862962003185	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.7e-75
862962003186	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
862962003187	FOG: CBS domain [General function prediction only]; Region: COG0517
862962003188	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962003189	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
862962003190	Substrate binding site; other site
862962003191	metal-binding site
862962003192	HMMPfam hit to PF00571, CBS domain, score 0.0057
862962003193	HMMPfam hit to PF00571, CBS domain, score 0.0012
862962003194	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.5e-17
862962003195	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962003196	8 probable transmembrane helices predicted for BF638R0793 by TMHMM2.0 at aa 35-52, 97-114, 127-149, 164-186, 199-221, 236-255, 267-289 and 321-340
862962003197	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962003198	HMMPfam hit to PF01501, Glycosyl transferase family, score 6.2e-05
862962003199	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962003200	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962003202	4 probable transmembrane helices predicted for BF638R0796 by TMHMM2.0 at aa 7-29, 49-67, 83-105 and 125-147
862962003203	HMMPfam hit to PF03062, MBOAT family, score 0.0021
862962003204	4 probable transmembrane helices predicted for BF638R0798 by TMHMM2.0 at aa 61-83, 118-140, 161-183 and 198-217
862962003205	PS00044 Bacterial regulatory proteins, lysR family signature.
862962003206	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
862962003207	catalytic triad [active]
862962003208	Signal peptide predicted for BF638R0799 by SignalP 2.0 HMM (Signal peptide probability 0.791) with cleavage site probability 0.347 between residues 33 and 34
862962003210	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
862962003211	active site
862962003212	HMMPfam hit to PF00535, Glycosyl transferase, score 4e-43
862962003213	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
862962003214	trimer interface [polypeptide binding]; other site
862962003215	active site
862962003216	substrate binding site [chemical binding]; other site
862962003217	CoA binding site [chemical binding]; other site
862962003218	Bacterial sugar transferase; Region: Bac_transf; pfam02397
862962003219	HMMPfam hit to PF02397, Bacterial sugar transferase, score 4.7e-24
862962003220	1 probable transmembrane helix predicted for BF638R0807 by TMHMM2.0 at aa 13-32
862962003221	potential frameshift: common BLAST hit: gi|150006502|ref|YP_001301246.1| transposase
862962003222	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
862962003223	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
862962003224	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962003225	inhibitor-cofactor binding pocket; inhibition site
862962003226	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962003227	catalytic residue [active]
862962003228	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.8e-113
862962003229	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
862962003230	non-specific DNA binding site [nucleotide binding]; other site
862962003231	salt bridge; other site
862962003232	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962003233	Signal peptide predicted for BF638R0813 by SignalP 2.0 HMM (Signal peptide probability 0.892) with cleavage site probability 0.728 between residues 21 and 22
862962003234	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
862962003235	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
862962003236	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962003237	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962003238	active site
862962003239	catalytic tetrad [active]
862962003240	HMMPfam hit to PF00248, Aldo/keto reductase family, score 4e-57
862962003241	Probable beta-xylosidase; Provisional; Region: PLN03080
862962003242	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962003243	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962003244	Signal peptide predicted for BF638R0816 by SignalP 2.0 HMM (Signal peptide probability 0.773) with cleavage site probability 0.759 between residues 23 and 24
862962003245	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 6.7e-90
862962003246	PS00775 Glycosyl hydrolases family 3 active site.
862962003247	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 3.6e-78
862962003248	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003249	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003250	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003251	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003252	Signal peptide predicted for BF638R0817 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.627 between residues 21 and 22
862962003253	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.4e-22
862962003254	HMMPfam hit to PF00593, TonB dependent receptor, score 8.5e-23
862962003255	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003256	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003257	SusD family; Region: SusD; pfam07980
862962003258	Signal peptide predicted for BF638R0818 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.741 between residues 25 and 26
862962003259	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003260	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
862962003261	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
862962003262	metal binding site [ion binding]; metal-binding site
862962003263	ligand binding site [chemical binding]; other site
862962003264	Signal peptide predicted for BF638R0821 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.690 between residues 23 and 24
862962003265	HMMPfam hit to PF03422, Carbohydrate binding module (family 6), score 6.2e-15
862962003266	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
862962003267	HMMPfam hit to PF02156, Glycosyl hydrolase family, score 4.2e-27
862962003268	Endo-beta-mannanase [Carbohydrate transport and metabolism]; Region: COG3934
862962003269	Signal peptide predicted for BF638R0823 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.445 between residues 25 and 26
862962003270	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
862962003271	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962003272	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962003273	Signal peptide predicted for BF638R0824 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 21 and 22
862962003274	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 1.8e-89
862962003275	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 7.3e-99
862962003276	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
862962003277	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
862962003278	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
862962003279	B12 binding site [chemical binding]; other site
862962003280	cobalt ligand [ion binding]; other site
862962003281	HMMPfam hit to PF02607, B12 binding domain, score 6e-17
862962003282	HMMPfam hit to PF02310, B12 binding domain, score 3.5e-33
862962003283	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
862962003284	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003285	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
862962003286	HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D), score 2.6e-09
862962003287	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
862962003288	Signal peptide predicted for BF638R0829 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.464 between residues 26 and 27
862962003289	HMMPfam hit to PF02156, Glycosyl hydrolase family, score 3.3e-31
862962003290	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
862962003291	active site
862962003292	MFS/sugar transport protein; Region: MFS_2; pfam13347
862962003293	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962003294	putative substrate translocation pore; other site
862962003295	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.8e-17
862962003296	11 probable transmembrane helices predicted for BF638R0831 by TMHMM2.0 at aa 30-52, 81-100, 110-132, 153-172, 182-204, 225-247, 273-295, 308-327, 331-353, 385-404 and 419-441
862962003297	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
862962003298	putative active cleft [active]
862962003299	HMMPfam hit to PF07221, N-acylglucosamine 2-epimerase (GlcNAc, score 4.9e-11
862962003300	8 probable transmembrane helices predicted for BF638R0833 by TMHMM2.0 at aa 9-31, 66-88, 101-120, 124-146, 153-175, 190-212, 231-253 and 268-290
862962003301	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962003302	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003303	PS00190 Cytochrome c family heme-binding site signature.
862962003304	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 14
862962003305	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 8.9e-05
862962003306	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.9
862962003307	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.38
862962003308	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.   The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_5; cd06153
862962003309	homotrimer interaction site [polypeptide binding]; other site
862962003310	putative active site [active]
862962003311	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003312	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003313	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 1.3e-08
862962003314	PS00962 Ribosomal protein S2 signature 1.
862962003315	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962003316	Signal peptide predicted for BF638R0837 by SignalP 2.0 HMM (Signal peptide probability 0.893) with cleavage site probability 0.786 between residues 23 and 24
862962003317	Signal peptide predicted for BF638R0838 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.771 between residues 26 and 27
862962003318	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003319	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003320	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
862962003321	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962003322	HMMPfam hit to PF00593, TonB dependent receptor, score 7.8e-20
862962003323	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003324	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.8e-08
862962003325	Signal peptide predicted for BF638R0839 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.884 between residues 23 and 24
862962003326	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
862962003327	GAF domain; Region: GAF; pfam01590
862962003328	PAS fold; Region: PAS_3; pfam08447
862962003329	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962003330	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962003331	dimer interface [polypeptide binding]; other site
862962003332	phosphorylation site [posttranslational modification]
862962003333	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962003334	ATP binding site [chemical binding]; other site
862962003335	Mg2+ binding site [ion binding]; other site
862962003336	G-X-G motif; other site
862962003337	HMMPfam hit to PF01590, GAF domain, score 1.2e-10
862962003338	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.5e-23
862962003339	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.2e-39
862962003340	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
862962003341	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
862962003342	13 probable transmembrane helices predicted for BF638R0841 by TMHMM2.0 at aa 13-30, 45-64, 85-102, 122-144, 165-187, 207-229, 242-264, 277-294, 301-323, 328-350, 370-392, 407-429 and 452-474
862962003343	HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 1.4e-61
862962003344	NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; Region: NuoM; COG1008
862962003345	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
862962003346	14 probable transmembrane helices predicted for BF638R0842 by TMHMM2.0 at aa 4-21, 28-50, 84-106, 113-131, 136-155, 168-190, 210-232, 244-266, 276-295, 302-321, 331-353, 373-395, 410-432 and 458-480
862962003347	HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 5.1e-68
862962003348	PS00338 Somatotropin, prolactin and related hormones signature 2.
862962003349	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
862962003350	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
862962003351	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
862962003352	16 probable transmembrane helices predicted for BF638R0843 by TMHMM2.0 at aa 4-26, 33-55, 91-113, 125-144, 148-165, 178-200, 210-232, 252-274, 284-305, 312-334, 349-371, 391-410, 425-447, 479-501, 516-535 and 618-635
862962003353	HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex, score 4.5e-105
862962003354	HMMPfam hit to PF00662, NADH-Ubiquinone oxidoreductase (complex, score 1.2e-17
862962003355	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
862962003356	HMMPfam hit to PF00420, NADH-ubiquinone/plastoquinone oxidoreduct, score 8.7e-24
862962003357	2 probable transmembrane helices predicted for BF638R0844 by TMHMM2.0 at aa 7-24 and 62-84
862962003358	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
862962003359	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
862962003360	HMMPfam hit to PF00499, NADH-ubiquinone/plastoquinone oxidoreduct, score 3.3e-06
862962003361	5 probable transmembrane helices predicted for BF638R0845 by TMHMM2.0 at aa 4-26, 33-55, 59-81, 94-113 and 145-167
862962003362	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
862962003363	4Fe-4S binding domain; Region: Fer4; cl02805
862962003364	4Fe-4S binding domain; Region: Fer4; pfam00037
862962003365	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 7.5e-08
862962003366	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962003367	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.8e-05
862962003368	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962003369	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
862962003370	8 probable transmembrane helices predicted for BF638R0847 by TMHMM2.0 at aa 24-46, 97-119, 129-151, 164-186, 201-223, 262-284, 299-321 and 334-356
862962003371	HMMPfam hit to PF00146, NADH dehydrogenase, score 3.7e-113
862962003372	PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2.
862962003373	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
862962003374	NADH dehydrogenase subunit D; Validated; Region: PRK06075
862962003375	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
862962003376	HMMPfam hit to PF00346, Respiratory-chain NADH dehydrogenase,, score 1.5e-68
862962003377	HMMPfam hit to PF00329, Respiratory-chain NADH dehydrogenase,, score 3.4e-27
862962003378	NADH dehydrogenase subunit B; Provisional; Region: PRK14816
862962003379	HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 Kd sub, score 3.8e-52
862962003380	PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature.
862962003381	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
862962003382	HMMPfam hit to PF00507, NADH-ubiquinone/plastoquinone oxidoreduct, score 7.8e-34
862962003383	3 probable transmembrane helices predicted for BF638R0850 by TMHMM2.0 at aa 5-27, 57-79 and 89-108
862962003384	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003385	Signal peptide predicted for BF638R0851 by SignalP 2.0 HMM (Signal peptide probability 0.872) with cleavage site probability 0.679 between residues 23 and 24
862962003386	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
862962003387	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
862962003388	HMMPfam hit to PF02386, Cation transport protein, score 3.5e-64
862962003389	10 probable transmembrane helices predicted for BF638R0852 by TMHMM2.0 at aa 12-31, 41-58, 70-92, 140-162, 183-205, 239-261, 274-296, 324-346, 390-412 and 455-477
862962003390	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
862962003391	TrkA-N domain; Region: TrkA_N; pfam02254
862962003392	TrkA-C domain; Region: TrkA_C; pfam02080
862962003393	TrkA-N domain; Region: TrkA_N; pfam02254
862962003394	TrkA-C domain; Region: TrkA_C; pfam02080
862962003395	HMMPfam hit to PF02080, TrkA-C domain, score 9.3e-14
862962003396	HMMPfam hit to PF02254, TrkA-N domain, score 6.3e-05
862962003397	HMMPfam hit to PF02080, TrkA-C domain, score 5.2e-12
862962003398	HMMPfam hit to PF02254, TrkA-N domain, score 1.3e-22
862962003399	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
862962003400	1-deoxy-D-xylulose-5-phosphate synthase; Region: DXP_synthase_N; pfam13292
862962003401	TPP-binding site [chemical binding]; other site
862962003402	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
862962003403	PYR/PP interface [polypeptide binding]; other site
862962003404	dimer interface [polypeptide binding]; other site
862962003405	TPP binding site [chemical binding]; other site
862962003406	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
862962003407	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 1.3e-25
862962003408	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.2e-49
862962003409	PS00802 Transketolase signature 2.
862962003410	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
862962003411	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
862962003412	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962003413	PS00120 Lipases, serine active site.
862962003414	Signal peptide predicted for BF638R0855 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.908 between residues 25 and 26
862962003415	3 probable transmembrane helices predicted for BF638R0856 by TMHMM2.0 at aa 21-43, 48-70 and 83-105
862962003416	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
862962003417	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962003418	motif II; other site
862962003419	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.3e-27
862962003420	PS01228 Hypothetical cof family signature 1.
862962003421	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962003422	Sulfatase; Region: Sulfatase; pfam00884
862962003423	HMMPfam hit to PF00884, Sulfatase, score 7.5e-32
862962003424	PS00523 Sulfatases signature 1.
862962003425	Signal peptide predicted for BF638R0858 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.625 between residues 21 and 22
862962003426	probable galactinol--sucrose galactosyltransferase 1; Region: PLN02355
862962003427	HMMPfam hit to PF05691, Raffinose synthase or seed imbibition p, score 7e-08
862962003428	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003429	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962003430	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
862962003431	Signal peptide predicted for BF638R0860 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.880 between residues 19 and 20
862962003432	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962003433	Sulfatase; Region: Sulfatase; cl17466
862962003434	HMMPfam hit to PF00884, Sulfatase, score 2.3e-39
862962003435	PS00523 Sulfatases signature 1.
862962003436	Signal peptide predicted for BF638R0861 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.965 between residues 21 and 22
862962003437	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003438	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003439	SusD family; Region: SusD; pfam07980
862962003440	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003441	Signal peptide predicted for BF638R0862 by SignalP 2.0 HMM (Signal peptide probability 0.705) with cleavage site probability 0.664 between residues 22 and 23
862962003442	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003443	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003444	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003445	HMMPfam hit to PF00593, TonB dependent receptor, score 2.5e-17
862962003446	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-19
862962003447	Signal peptide predicted for BF638R0863 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.910 between residues 19 and 20
862962003448	Two component regulator propeller; Region: Reg_prop; pfam07494
862962003449	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962003450	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962003451	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962003452	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962003453	dimer interface [polypeptide binding]; other site
862962003454	phosphorylation site [posttranslational modification]
862962003455	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962003456	ATP binding site [chemical binding]; other site
862962003457	Mg2+ binding site [ion binding]; other site
862962003458	G-X-G motif; other site
862962003459	Response regulator receiver domain; Region: Response_reg; pfam00072
862962003460	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962003461	active site
862962003462	phosphorylation site [posttranslational modification]
862962003463	intermolecular recognition site; other site
862962003464	dimerization interface [polypeptide binding]; other site
862962003465	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962003466	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962003467	2 probable transmembrane helices predicted for BF638R0864 by TMHMM2.0 at aa 7-29 and 795-817
862962003468	HMMPfam hit to PF07495, Two component regulator three Y motif, score 2.5e-07
862962003469	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2e-13
862962003470	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.5e-28
862962003471	HMMPfam hit to PF00072, Response regulator receiver domain, score 8.4e-33
862962003472	PS00041 Bacterial regulatory proteins, araC family signature.
862962003473	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 4.6e-08
862962003474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962003475	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962003476	putative substrate translocation pore; other site
862962003477	11 probable transmembrane helices predicted for BF638R0865 by TMHMM2.0 at aa 30-47, 71-93, 100-122, 142-164, 189-211, 216-238, 286-308, 323-345, 366-388, 421-443 and 464-483
862962003478	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.2e-46
862962003479	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
862962003480	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962003481	Signal peptide predicted for BF638R0866 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.640 between residues 24 and 25
862962003482	HMMPfam hit to PF01120, Alpha-L-fucosidase, score 2e-18
862962003483	Peptide-N-glycosidase F, N terminal; Region: N-glycanase_N; pfam09112
862962003484	Peptide-N-glycosidase F, C terminal; Region: N-glycanase_C; pfam09113
862962003485	Signal peptide predicted for BF638R0867 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.999 between residues 20 and 21
862962003486	Part of AAA domain; Region: AAA_19; pfam13245
862962003487	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
862962003488	AAA domain; Region: AAA_12; pfam13087
862962003489	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003490	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
862962003491	HMMPfam hit to PF01757, Acyltransferase family, score 3.9e-32
862962003492	10 probable transmembrane helices predicted for BF638R0869 by TMHMM2.0 at aa 33-55, 70-89, 110-132, 162-184, 189-206, 216-238, 251-270, 275-295, 308-330 and 343-365
862962003493	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
862962003494	HMMPfam hit to PF00902, Sec-independent protein translocase protein, score 3e-50
862962003495	5 probable transmembrane helices predicted for BF638R0870 by TMHMM2.0 at aa 20-42, 90-112, 133-155, 186-208 and 221-243
862962003496	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
862962003497	HMMPfam hit to PF02416, mttA/Hcf106 family, score 9.4e-16
862962003498	1 probable transmembrane helix predicted for BF638R0871 by TMHMM2.0 at aa 5-27
862962003499	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
862962003500	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
862962003501	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962003502	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
862962003503	active site
862962003504	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
862962003505	dimer interface [polypeptide binding]; other site
862962003506	substrate binding site [chemical binding]; other site
862962003507	catalytic residues [active]
862962003508	HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 4.8e-47
862962003509	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 1e-55
862962003510	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase do, score 0.011
862962003511	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 3e-09
862962003512	GSCFA family; Region: GSCFA; pfam08885
862962003513	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003514	Penicillinase repressor; Region: Pencillinase_R; pfam03965
862962003515	HMMPfam hit to PF03965, Penicillinase repressor, score 5.4e-37
862962003516	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
862962003517	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003518	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962003519	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003520	4 probable transmembrane helices predicted for BF638R0878 by TMHMM2.0 at aa 5-27, 39-58, 89-111 and 267-289
862962003521	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
862962003522	Histidine kinase; Region: HisKA_3; pfam07730
862962003523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962003524	ATP binding site [chemical binding]; other site
862962003525	Mg2+ binding site [ion binding]; other site
862962003526	G-X-G motif; other site
862962003527	Signal peptide predicted for BF638R0880 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.601 between residues 20 and 21
862962003528	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.4
862962003529	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.16
862962003530	1 probable transmembrane helix predicted for BF638R0880 by TMHMM2.0 at aa 406-425
862962003531	HMMPfam hit to PF07730, Histidine kinase, score 3.2e-06
862962003532	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9.3e-25
862962003533	PS00237 G-protein coupled receptors signature.
862962003534	Signal peptide predicted for BF638R0882 by SignalP 2.0 HMM (Signal peptide probability 0.750) with cleavage site probability 0.282 between residues 34 and 35
862962003535	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
862962003536	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
862962003537	HMMPfam hit to PF01715, IPP transferase, score 7e-66
862962003538	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003539	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
862962003540	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
862962003541	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
862962003542	active site
862962003543	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.39
862962003544	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.034
862962003545	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.45
862962003546	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.065
862962003547	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
862962003548	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
862962003549	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
862962003550	HMMPfam hit to PF03061, Thioesterase superfamily, score 7.2e-13
862962003551	HMMPfam hit to PF03331, UDP-3-O-acyl N-acetylglycosamine deacetylase, score 3.2e-75
862962003552	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
862962003553	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
862962003554	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
862962003555	trimer interface [polypeptide binding]; other site
862962003556	active site
862962003557	UDP-GlcNAc binding site [chemical binding]; other site
862962003558	lipid binding site [chemical binding]; lipid-binding site
862962003559	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0014
862962003560	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.039
862962003561	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0013
862962003562	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.043
862962003563	HMMPfam hit to PF04613, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-a, score 8.3e-16
862962003564	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
862962003565	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962003566	Zn2+ binding site [ion binding]; other site
862962003567	Mg2+ binding site [ion binding]; other site
862962003568	HMMPfam hit to PF01966, HD domain, score 0.00011
862962003569	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
862962003570	active site
862962003571	dimer interface [polypeptide binding]; other site
862962003572	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 1.7e-24
862962003573	peptide chain release factor 1; Validated; Region: prfA; PRK00591
862962003574	This domain is found in peptide chain release factors; Region: PCRF; smart00937
862962003575	RF-1 domain; Region: RF-1; pfam00472
862962003576	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 5.5e-42
862962003577	HMMPfam hit to PF03462, PCRF domain, score 1.5e-58
862962003578	phosphoribosylaminoimidazole synthetase; Region: purM; TIGR00878
862962003579	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
862962003580	dimerization interface [polypeptide binding]; other site
862962003581	ATP binding site [chemical binding]; other site
862962003582	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 0.00025
862962003583	1 probable transmembrane helix predicted for BF638R0892 by TMHMM2.0 at aa 15-37
862962003584	LemA family; Region: LemA; pfam04011
862962003585	HMMPfam hit to PF04011, LemA family, score 3.6e-100
862962003586	1 probable transmembrane helix predicted for BF638R0893 by TMHMM2.0 at aa 87-109
862962003587	Repair protein; Region: Repair_PSII; pfam04536
862962003588	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
862962003589	1 probable transmembrane helix predicted for BF638R0894 by TMHMM2.0 at aa 216-238
862962003590	HMMPfam hit to PF04536, Domain of unknown function (DUF477), score 5.7e-45
862962003591	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
862962003592	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
862962003593	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962003594	Signal peptide predicted for BF638R0895 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.346 between residues 27 and 28
862962003595	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
862962003596	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
862962003597	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
862962003598	shikimate binding site; other site
862962003599	NAD(P) binding site [chemical binding]; other site
862962003600	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 4.1e-45
862962003601	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
862962003602	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962003603	S-adenosylmethionine binding site [chemical binding]; other site
862962003604	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 2.9e-59
862962003605	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
862962003606	ATP binding site [chemical binding]; other site
862962003607	active site
862962003608	substrate binding site [chemical binding]; other site
862962003609	HMMPfam hit to PF01259, SAICAR synthetase, score 1e-79
862962003610	PS01058 SAICAR synthetase signature 2.
862962003611	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
862962003612	PhoH-like protein; Region: PhoH; pfam02562
862962003613	HMMPfam hit to PF02562, PhoH-like protein, score 1.2e-122
862962003614	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962003615	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003616	1 probable transmembrane helix predicted for BF638R0900 by TMHMM2.0 at aa 7-25
862962003617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
862962003618	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
862962003619	HMMPfam hit to PF01145, SPFH domain / Band, score 1.3e-14
862962003620	1 probable transmembrane helix predicted for BF638R0901 by TMHMM2.0 at aa 7-24
862962003621	3 probable transmembrane helices predicted for BF638R0902 by TMHMM2.0 at aa 5-27, 40-62 and 67-89
862962003622	Signal peptide predicted for BF638R0903 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.742 between residues 22 and 23
862962003623	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003624	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
862962003625	Flavin Reductases; Region: FlaRed; cl00801
862962003626	Signal peptide predicted for BF638R0904 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.681 between residues 18 and 19
862962003627	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
862962003628	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
862962003629	dimerization interface 3.5A [polypeptide binding]; other site
862962003630	active site
862962003631	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.8e-26
862962003632	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.9e-15
862962003633	EamA-like transporter family; Region: EamA; cl17759
862962003634	EamA-like transporter family; Region: EamA; pfam00892
862962003635	10 probable transmembrane helices predicted for BF638R0907 by TMHMM2.0 at aa 4-19, 32-54, 69-91, 98-120, 130-147, 159-176, 191-210, 223-245, 255-272 and 281-298
862962003636	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.9e-08
862962003637	PS00678 Trp-Asp (WD) repeats signature.
862962003638	Protein of unknown function (DUF3256); Region: DUF3256; pfam11644
862962003639	Signal peptide predicted for BF638R0908 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.942 between residues 23 and 24
862962003640	Phosphotransferase enzyme family; Region: APH; pfam01636
862962003641	HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 1.7e-20
862962003642	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
862962003643	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962003644	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962003645	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962003646	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
862962003647	HMMPfam hit to PF02930, Beta galactosidase small chain, C ter, score 2.6e-14
862962003648	HMMPfam hit to PF02929, Beta galactosidase small chain, N ter, score 4e-23
862962003649	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 4.7e-95
862962003650	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 1.4e-18
862962003651	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 2.3e-81
862962003652	Signal peptide predicted for BF638R0910 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.986 between residues 26 and 27
862962003653	Uncharacterized conserved protein [Function unknown]; Region: COG1284
862962003654	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
862962003655	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
862962003656	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
862962003657	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1e-18
862962003658	5 probable transmembrane helices predicted for BF638R0911 by TMHMM2.0 at aa 21-38, 53-75, 82-104, 119-141 and 161-180
862962003659	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 5.3e-20
862962003660	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
862962003661	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962003662	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 8.7e-13
862962003663	Signal peptide predicted for BF638R0912 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.979 between residues 23 and 24
862962003664	Signal peptide predicted for BF638R0915 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.916 between residues 19 and 20
862962003665	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962003666	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962003667	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
862962003668	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 2.6e-16
862962003669	Signal peptide predicted for BF638R0916 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 27 and 28
862962003670	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962003671	TPR motif; other site
862962003672	binding surface
862962003673	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962003674	binding surface
862962003675	TPR motif; other site
862962003676	TPR repeat; Region: TPR_11; pfam13414
862962003677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962003678	binding surface
862962003679	TPR motif; other site
862962003680	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.055
862962003681	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.054
862962003682	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00058
862962003683	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.97
862962003684	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.25
862962003685	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.56
862962003686	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
862962003687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962003688	putative substrate translocation pore; other site
862962003689	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
862962003690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962003691	HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.2e-134
862962003692	12 probable transmembrane helices predicted for BF638R0918 by TMHMM2.0 at aa 7-29, 49-71, 80-97, 103-125, 137-159, 179-201, 262-284, 299-321, 330-352, 357-379, 392-414 and 418-438
862962003693	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.5e-36
862962003694	PS00216 Sugar transport proteins signature 1.
862962003695	PS00217 Sugar transport proteins signature 2.
862962003696	PS00216 Sugar transport proteins signature 1.
862962003697	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
862962003698	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962003699	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962003700	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962003701	HMMPfam hit to PF02311, AraC-like ligand binding domain, score 1.6e-10
862962003702	HMMPfam hit to PF07883, Cupin domain, score 0.002
862962003703	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 3e-11
862962003704	PS00041 Bacterial regulatory proteins, araC family signature.
862962003705	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 3.3e-12
862962003706	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962003707	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
862962003708	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
862962003709	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
862962003710	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962003711	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 5.8e-72
862962003712	HMMPfam hit to PF07691, PA14 domain, score 5.7e-05
862962003713	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 1.7e-90
862962003714	Signal peptide predicted for BF638R0920 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 22 and 23
862962003715	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
862962003716	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.33
862962003717	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.2
862962003718	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 3.4
862962003719	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.1
862962003720	PS00190 Cytochrome c family heme-binding site signature.
862962003721	Signal peptide predicted for BF638R0921 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.850 between residues 18 and 19
862962003722	5 probable transmembrane helices predicted for BF638R0922 by TMHMM2.0 at aa 7-29, 65-87, 100-117, 121-143 and 164-186
862962003723	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003724	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003725	SusD family; Region: SusD; pfam07980
862962003726	Signal peptide predicted for BF638R0923 by SignalP 2.0 HMM (Signal peptide probability 0.630) with cleavage site probability 0.341 between residues 21 and 22
862962003727	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962003728	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003729	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003730	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003731	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962003732	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003733	HMMPfam hit to PF00593, TonB dependent receptor, score 2.3e-15
862962003734	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.7e-19
862962003735	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 1.3e-12
862962003736	Signal peptide predicted for BF638R0924 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 36 and 37
862962003737	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003738	SusD family; Region: SusD; pfam07980
862962003739	PS00037 Myb DNA-binding domain repeat signature 1.
862962003740	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003741	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962003742	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003743	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003744	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003745	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003746	HMMPfam hit to PF00593, TonB dependent receptor, score 3.5e-12
862962003747	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962003748	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.6e-21
862962003749	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 5.7e-11
862962003750	Signal peptide predicted for BF638R0926 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.984 between residues 36 and 37
862962003751	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003752	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962003753	SusD family; Region: SusD; pfam07980
862962003754	Signal peptide predicted for BF638R0927 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.889 between residues 16 and 17
862962003755	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962003756	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003757	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003758	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962003759	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003760	HMMPfam hit to PF00593, TonB dependent receptor, score 5.9e-15
862962003761	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.9e-16
862962003762	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 3.2e-10
862962003763	Signal peptide predicted for BF638R0928 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.988 between residues 36 and 37
862962003764	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962003765	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962003766	DNA binding residues [nucleotide binding]
862962003767	HMMPfam hit to PF04542, Sigma-70 region, score 8.6e-09
862962003768	HMMPfam hit to PF04545, Sigma-70, region, score 6.1e-13
862962003769	FecR protein; Region: FecR; pfam04773
862962003770	1 probable transmembrane helix predicted for BF638R0931 by TMHMM2.0 at aa 80-102
862962003771	HMMPfam hit to PF04773, FecR protein, score 1.2e-27
862962003772	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962003773	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003774	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003775	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003776	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003777	Signal peptide predicted for BF638R0932 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 36 and 37
862962003778	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 1.3e-12
862962003779	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-20
862962003780	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962003781	HMMPfam hit to PF00593, TonB dependent receptor, score 6.3e-16
862962003782	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003783	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003784	SusD family; Region: SusD; pfam07980
862962003785	Signal peptide predicted for BF638R0933 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.888 between residues 23 and 24
862962003786	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
862962003787	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962003788	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 3.1e-11
862962003789	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
862962003790	homopentamer interface [polypeptide binding]; other site
862962003791	active site
862962003792	HMMPfam hit to PF00885, 6,7-dimethyl-8-ribityllumazine synthase, score 1.5e-55
862962003793	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
862962003794	TPR motif; other site
862962003795	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.067
862962003796	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.013
862962003797	1 probable transmembrane helix predicted for BF638R0936 by TMHMM2.0 at aa 30-52
862962003798	recombination protein F; Reviewed; Region: recF; PRK00064
862962003799	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962003800	Walker A/P-loop; other site
862962003801	ATP binding site [chemical binding]; other site
862962003802	Q-loop/lid; other site
862962003803	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962003804	ABC transporter signature motif; other site
862962003805	Walker B; other site
862962003806	D-loop; other site
862962003807	H-loop/switch region; other site
862962003808	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003809	PS00192 Cytochrome b/b6 heme-ligand signature.
862962003810	Protein of unknown function (DUF721); Region: DUF721; pfam05258
862962003811	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
862962003812	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
862962003813	active site
862962003814	dimer interface [polypeptide binding]; other site
862962003815	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
862962003816	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
862962003817	HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 8.1e-34
862962003818	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
862962003819	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962003820	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
862962003821	protein binding site [polypeptide binding]; other site
862962003822	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
862962003823	Catalytic dyad [active]
862962003824	HMMPfam hit to PF03572, Peptidase family S41, score 2.9e-71
862962003825	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 2.5e-09
862962003826	1 probable transmembrane helix predicted for BF638R0941 by TMHMM2.0 at aa 7-29
862962003827	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
862962003828	catalytic motif [active]
862962003829	Zn binding site [ion binding]; other site
862962003830	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase, score 2.9e-31
862962003831	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
862962003832	Signal peptide predicted for BF638R0943 by SignalP 2.0 HMM (Signal peptide probability 0.976) with cleavage site probability 0.545 between residues 18 and 19
862962003833	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
862962003834	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
862962003835	active site
862962003836	Zn binding site [ion binding]; other site
862962003837	HMMPfam hit to PF01432, Peptidase family M3, score 4e-160
862962003838	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962003839	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
862962003840	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
862962003841	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
862962003842	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 1.3e-115
862962003843	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
862962003844	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 1.8e-96
862962003845	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
862962003846	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
862962003847	HMMPfam hit to PF01741, Large-conductance mechanosensitive channel,, score 3.6e-71
862962003848	PS01327 Large-conductance mechanosensitive channels mscL family signature.
862962003849	2 probable transmembrane helices predicted for BF638R0946 by TMHMM2.0 at aa 23-45 and 86-108
862962003850	GMP synthase; Reviewed; Region: guaA; PRK00074
862962003851	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
862962003852	AMP/PPi binding site [chemical binding]; other site
862962003853	candidate oxyanion hole; other site
862962003854	catalytic triad [active]
862962003855	potential glutamine specificity residues [chemical binding]; other site
862962003856	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
862962003857	ATP Binding subdomain [chemical binding]; other site
862962003858	Ligand Binding sites [chemical binding]; other site
862962003859	Dimerization subdomain; other site
862962003860	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.7e-35
862962003861	PS00442 Glutamine amidotransferases class-I active site.
862962003862	HMMPfam hit to PF00958, GMP synthase C terminal domain, score 5.3e-65
862962003863	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
862962003864	Helix-turn-helix domain; Region: HTH_38; pfam13936
862962003865	Homeodomain-like domain; Region: HTH_32; pfam13565
862962003866	Integrase core domain; Region: rve; pfam00665
862962003867	HMMPfam hit to PF00665, Integrase core domain, score 1.6e-26
862962003868	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003869	SusD family; Region: SusD; pfam07980
862962003870	Signal peptide predicted for BF638R0949 by SignalP 2.0 HMM (Signal peptide probability 0.630) with cleavage site probability 0.254 between residues 23 and 24
862962003871	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003872	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003873	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003874	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003875	HMMPfam hit to PF00593, TonB dependent receptor, score 2.9e-16
862962003876	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
862962003877	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.8e-22
862962003878	Signal peptide predicted for BF638R0950 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.942 between residues 40 and 41
862962003879	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962003880	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962003881	SusD family; Region: SusD; pfam07980
862962003882	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962003883	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962003884	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962003885	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962003886	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962003887	HMMPfam hit to PF00593, TonB dependent receptor, score 6e-15
862962003888	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-20
862962003889	Signal peptide predicted for BF638R0952 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.962 between residues 40 and 41
862962003890	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
862962003891	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
862962003892	NAD binding site [chemical binding]; other site
862962003893	homotetramer interface [polypeptide binding]; other site
862962003894	homodimer interface [polypeptide binding]; other site
862962003895	substrate binding site [chemical binding]; other site
862962003896	active site
862962003897	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
862962003898	Signal peptide predicted for BF638R0954 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.471 between residues 50 and 51
862962003899	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
862962003900	putative SAM binding site [chemical binding]; other site
862962003901	homodimer interface [polypeptide binding]; other site
862962003902	5 probable transmembrane helices predicted for BF638R0956 by TMHMM2.0 at aa 15-37, 58-80, 90-107, 135-157 and 167-189
862962003903	lipoyl synthase; Provisional; Region: PRK05481
862962003904	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962003905	FeS/SAM binding site; other site
862962003906	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.3e-16
862962003907	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
862962003908	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962003909	HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 2.6e-64
862962003910	PS00708 Prolyl endopeptidase family serine active site.
862962003911	HMMPfam hit to PF00930, Dipeptidyl peptidase IV (DPP IV) N-termi, score 4.2e-168
862962003912	Signal peptide predicted for BF638R0958 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.602 between residues 21 and 22
862962003913	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
862962003914	4 probable transmembrane helices predicted for BF638R0960 by TMHMM2.0 at aa 13-35, 39-61, 68-85 and 89-108
862962003915	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962003916	LytTr DNA-binding domain; Region: LytTR; smart00850
862962003917	4 probable transmembrane helices predicted for BF638R0961 by TMHMM2.0 at aa 13-35, 45-67, 74-96 and 111-130
862962003918	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 3.4e-26
862962003919	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
862962003920	HMMPfam hit to PF04055, Radical SAM superfamily, score 2.4e-09
862962003921	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
862962003922	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
862962003923	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
862962003924	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 3.7e-18
862962003925	HMMPfam hit to PF00258, Flavodoxin, score 6.8e-13
862962003926	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
862962003927	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
862962003928	active site
862962003929	trimer interface [polypeptide binding]; other site
862962003930	allosteric site; other site
862962003931	active site lid [active]
862962003932	hexamer (dimer of trimers) interface [polypeptide binding]; other site
862962003933	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 3.7e-168
862962003934	PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature.
862962003935	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
862962003936	HMMPfam hit to PF02987, no description, score 0.11
862962003937	Signal peptide predicted for BF638R0965 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.623 between residues 16 and 17
862962003938	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
862962003939	HMMPfam hit to PF01300, yrdC domain, score 1.1e-34
862962003940	PS01147 SUA5/yciO/yrdC family signature.
862962003941	Family of unknown function (DUF490); Region: DUF490; pfam04357
862962003942	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
862962003943	1 probable transmembrane helix predicted for BF638R0968 by TMHMM2.0 at aa 25-47
862962003944	PIF1-like helicase; Region: PIF1; pfam05970
862962003945	AAA domain; Region: AAA_30; pfam13604
862962003946	Family description; Region: UvrD_C_2; pfam13538
862962003947	TPR repeat; Region: TPR_11; pfam13414
862962003948	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962003949	binding surface
862962003950	TPR motif; other site
862962003951	TPR repeat; Region: TPR_11; pfam13414
862962003952	TPR repeat; Region: TPR_11; pfam13414
862962003953	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 5.1e-05
862962003954	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0015
862962003955	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.15
862962003956	1 probable transmembrane helix predicted for BF638R0969 by TMHMM2.0 at aa 51-73
862962003957	PS00017 ATP/GTP-binding site motif A (P-loop).
862962003958	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
862962003959	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
862962003960	active site
862962003961	motif I; other site
862962003962	motif II; other site
862962003963	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962003964	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.5e-12
862962003965	PS01229 Hypothetical cof family signature 2.
862962003966	PS01228 Hypothetical cof family signature 1.
862962003967	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
862962003968	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962003969	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962003970	homodimer interface [polypeptide binding]; other site
862962003971	catalytic residue [active]
862962003972	HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.9e-08
862962003973	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
862962003974	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
862962003975	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962003976	catalytic residue [active]
862962003977	HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 1.7e-88
862962003978	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962003979	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962003980	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962003981	HMMPfam hit to PF04542, Sigma-70 region, score 0.00024
862962003982	HMMPfam hit to PF04545, Sigma-70, region, score 4.8e-15
862962003983	FecR protein; Region: FecR; pfam04773
862962003984	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962003985	1 probable transmembrane helix predicted for BF638R0974 by TMHMM2.0 at aa 64-86
862962003986	HMMPfam hit to PF04773, FecR protein, score 1.3e-28
862962003987	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962003988	1 probable transmembrane helix predicted for BF638R0975 by TMHMM2.0 at aa 21-38
862962003989	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962003990	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962003991	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
862962003992	PS00888 Cyclic nucleotide-binding domain signature 1.
862962003993	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
862962003994	HMMPfam hit to PF01914, MarC family integral membrane protein, score 3.4e-20
862962003995	6 probable transmembrane helices predicted for BF638R0977 by TMHMM2.0 at aa 45-67, 79-98, 108-130, 139-161, 166-185 and 206-228
862962003996	Rhomboid family; Region: Rhomboid; pfam01694
862962003997	HMMPfam hit to PF01694, Rhomboid family, score 2.8e-07
862962003998	6 probable transmembrane helices predicted for BF638R0978 by TMHMM2.0 at aa 9-31, 57-79, 86-105, 109-131, 138-160 and 170-187
862962003999	Glycogen debranching enzyme N terminal; Region: GDE_N; pfam12439
862962004000	glycogen debranching enzyme, archaeal type, putative; Region: gde_arch; TIGR01561
862962004001	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
862962004002	HMMPfam hit to PF06202, Amylo-alpha-1,6-glucosidase, score 5.8e-44
862962004003	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
862962004004	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962004005	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.7e-37
862962004006	N-terminal catalytic domain of a thermoactive alpha-amylase from Methanococcus jannaschii and similar proteins; glycoside hydrolase family 57 (GH57); Region: GH57N_MJA1_like; cd10795
862962004007	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
862962004008	putative active site [active]
862962004009	catalytic site [active]
862962004010	HMMPfam hit to PF03065, Glycosyl hydrolase family, score 2.3e-58
862962004011	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
862962004012	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004013	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
862962004014	Pantoate-beta-alanine ligase; Region: PanC; cd00560
862962004015	pantoate--beta-alanine ligase; Region: panC; TIGR00018
862962004016	active site
862962004017	ATP-binding site [chemical binding]; other site
862962004018	pantoate-binding site; other site
862962004019	HXXH motif; other site
862962004020	HMMPfam hit to PF02569, Pantoate-beta-alanine ligase, score 2.2e-112
862962004021	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
862962004022	tetramerization interface [polypeptide binding]; other site
862962004023	active site
862962004024	HMMPfam hit to PF02261, Aspartate decarboxylase, score 4.1e-62
862962004025	putative bifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta; Provisional; Region: PRK12778
862962004026	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
862962004027	FAD binding pocket [chemical binding]; other site
862962004028	FAD binding motif [chemical binding]; other site
862962004029	phosphate binding motif [ion binding]; other site
862962004030	beta-alpha-beta structure motif; other site
862962004031	NAD binding pocket [chemical binding]; other site
862962004032	Iron coordination center [ion binding]; other site
862962004033	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
862962004034	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
862962004035	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962004036	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.3e-30
862962004037	HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 7.3e-06
862962004038	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
862962004039	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962004040	12 probable transmembrane helices predicted for BF638R0988 by TMHMM2.0 at aa 12-33, 48-65, 72-94, 104-126, 139-161, 174-196, 229-251, 262-284, 291-313, 317-339, 348-370 and 374-396
862962004041	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.2e-18
862962004042	seryl-tRNA synthetase; Provisional; Region: PRK05431
862962004043	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
862962004044	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
862962004045	dimer interface [polypeptide binding]; other site
862962004046	active site
862962004047	motif 1; other site
862962004048	motif 2; other site
862962004049	motif 3; other site
862962004050	HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 3.2e-48
862962004051	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962004052	HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain, score 3.9e-31
862962004053	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
862962004054	HMMPfam hit to PF01016, Ribosomal L27 protein, score 6.5e-52
862962004055	PS00831 Ribosomal protein L27 signature.
862962004056	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
862962004057	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
862962004058	HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein, score 2.6e-50
862962004059	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
862962004060	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962004061	motif II; other site
862962004062	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.8e-31
862962004063	NlpC/P60 family; Region: NLPC_P60; pfam00877
862962004064	HMMPfam hit to PF00877, NlpC/P60 family, score 4.2e-32
862962004065	Signal peptide predicted for BF638R0996 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.829 between residues 24 and 25
862962004066	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
862962004067	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
862962004068	Walker A/P-loop; other site
862962004069	ATP binding site [chemical binding]; other site
862962004070	Q-loop/lid; other site
862962004071	ABC transporter signature motif; other site
862962004072	Walker B; other site
862962004073	D-loop; other site
862962004074	H-loop/switch region; other site
862962004075	HMMPfam hit to PF00005, ABC transporter, score 2.8e-37
862962004076	PS00211 ABC transporters family signature.
862962004077	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004078	12 probable transmembrane helices predicted for BF638R0998 by TMHMM2.0 at aa 29-51, 61-83, 117-139, 143-162, 169-191, 206-228, 283-301, 311-333, 354-373, 383-405, 426-448 and 452-474
862962004079	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962004080	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
862962004081	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962004082	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962004083	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962004084	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 1.9e-14
862962004085	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 3.1e-19
862962004086	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 4.8e-26
862962004087	PS00143 Insulinase family, zinc-binding region signature.
862962004088	Signal peptide predicted for BF638R0999 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 32 and 33
862962004089	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
862962004090	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
862962004091	HMMPfam hit to PF00793, DAHP synthetase I family, score 7.4e-87
862962004092	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004093	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
862962004094	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
862962004095	1 probable transmembrane helix predicted for BF638R1001 by TMHMM2.0 at aa 170-187
862962004096	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 1.2e-29
862962004097	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962004098	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
862962004099	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
862962004100	HMMPfam hit to PF01715, IPP transferase, score 1.1e-29
862962004101	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004102	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
862962004103	4 probable transmembrane helices predicted for BF638R1003 by TMHMM2.0 at aa 13-35, 279-301, 330-352 and 367-389
862962004104	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004105	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962004106	Walker A/P-loop; other site
862962004107	ATP binding site [chemical binding]; other site
862962004108	ABC transporter; Region: ABC_tran; pfam00005
862962004109	Q-loop/lid; other site
862962004110	ABC transporter signature motif; other site
862962004111	Walker B; other site
862962004112	D-loop; other site
862962004113	H-loop/switch region; other site
862962004114	HMMPfam hit to PF00005, ABC transporter, score 3.2e-24
862962004115	PS00211 ABC transporters family signature.
862962004116	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004117	Signal peptide predicted for BF638R1005 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.314 between residues 25 and 26
862962004118	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004119	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
862962004120	RNA methyltransferase, RsmE family; Region: TIGR00046
862962004121	HMMPfam hit to PF04452, Protein of unknown function (DUF558), score 1.9e-16
862962004122	Bifunctional nuclease; Region: DNase-RNase; pfam02577
862962004123	UvrB/uvrC motif; Region: UVR; pfam02151
862962004124	HMMPfam hit to PF02151, UvrB/uvrC motif, score 0.0023
862962004125	HMMPfam hit to PF02577, Uncharacterised ACR, COG1259, score 2.4e-26
862962004126	nucleoside transporter; Region: 2A0110; TIGR00889
862962004127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
862962004128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962004129	HMMPfam hit to PF03825, Nucleoside H+ symporter, score 5.5e-186
862962004130	12 probable transmembrane helices predicted for BF638R1008 by TMHMM2.0 at aa 7-29, 39-61, 68-87, 97-119, 132-150, 160-179, 211-233, 253-275, 282-299, 304-326, 346-368 and 383-405
862962004131	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.2e-07
862962004132	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004133	Signal peptide predicted for BF638R1009 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.412 between residues 23 and 24
862962004134	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004135	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
862962004136	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
862962004137	putative RNA binding site [nucleotide binding]; other site
862962004138	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962004139	S-adenosylmethionine binding site [chemical binding]; other site
862962004140	DEDDy 3'-5' exonuclease domain of WRN and similar proteins; Region: WRN_exo; cd06141
862962004141	catalytic site [active]
862962004142	putative active site [active]
862962004143	putative substrate binding site [chemical binding]; other site
862962004144	HMMPfam hit to PF01612, 3'-5' exonuclease, score 1.1e-10
862962004145	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
862962004146	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
862962004147	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
862962004148	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
862962004149	Signal peptide predicted for BF638R1013 by SignalP 2.0 HMM (Signal peptide probability 0.683) with cleavage site probability 0.550 between residues 56 and 57
862962004150	5 probable transmembrane helices predicted for BF638R1013 by TMHMM2.0 at aa 31-53, 91-113, 126-148, 153-170 and 177-199
862962004151	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 3.6e-55
862962004152	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004153	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
862962004154	Signal peptide predicted for BF638R1014 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.981 between residues 22 and 23
862962004155	1 probable transmembrane helix predicted for BF638R1014 by TMHMM2.0 at aa 7-24
862962004156	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
862962004157	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
862962004158	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962004159	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreducta, score 1.2e-64
862962004160	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
862962004161	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962004162	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962004163	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962004164	active site
862962004165	Fn3 associated; Region: Fn3_assoc; pfam13287
862962004166	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004167	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 4e-173
862962004168	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.0062
862962004169	Signal peptide predicted for BF638R1016 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.635 between residues 22 and 23
862962004170	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962004171	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962004172	ligand binding site [chemical binding]; other site
862962004173	flexible hinge region; other site
862962004174	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
862962004175	putative switch regulator; other site
862962004176	non-specific DNA interactions [nucleotide binding]; other site
862962004177	DNA binding site [nucleotide binding]
862962004178	sequence specific DNA binding site [nucleotide binding]; other site
862962004179	putative cAMP binding site [chemical binding]; other site
862962004180	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 8.7e-13
862962004181	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
862962004182	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
862962004183	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
862962004184	HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 1.4e-14
862962004185	PS00181 Glutamine synthetase putative ATP-binding region signature.
862962004186	Signal peptide predicted for BF638R1019 by SignalP 2.0 HMM (Signal peptide probability 0.668) with cleavage site probability 0.578 between residues 23 and 24
862962004187	1 probable transmembrane helix predicted for BF638R1019 by TMHMM2.0 at aa 5-27
862962004188	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
862962004189	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962004190	putative active site [active]
862962004191	putative NTP binding site [chemical binding]; other site
862962004192	putative nucleic acid binding site [nucleotide binding]; other site
862962004193	HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent DNA pol, score 4.2e-23
862962004194	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
862962004195	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
862962004196	RNA binding site [nucleotide binding]; other site
862962004197	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
862962004198	RNA binding site [nucleotide binding]; other site
862962004199	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
862962004200	RNA binding site [nucleotide binding]; other site
862962004201	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
862962004202	RNA binding site [nucleotide binding]; other site
862962004203	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
862962004204	RNA binding site [nucleotide binding]; other site
862962004205	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
862962004206	RNA binding site [nucleotide binding]; other site
862962004207	HMMPfam hit to PF00575, S1 RNA binding domain, score 8e-11
862962004208	HMMPfam hit to PF00575, S1 RNA binding domain, score 1.8e-12
862962004209	HMMPfam hit to PF00575, S1 RNA binding domain, score 7.4e-25
862962004210	HMMPfam hit to PF00575, S1 RNA binding domain, score 4.4e-20
862962004211	HMMPfam hit to PF00575, S1 RNA binding domain, score 2.7e-25
862962004212	HMMPfam hit to PF00575, S1 RNA binding domain, score 9.6e-10
862962004213	ribonuclease Z; Region: RNase_Z; TIGR02651
862962004214	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.1e-11
862962004215	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962004216	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962004217	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962004218	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962004219	DNA binding residues [nucleotide binding]
862962004220	HMMPfam hit to PF04542, Sigma-70 region, score 2.3e-16
862962004221	1 probable transmembrane helix predicted for BF638R1024 by TMHMM2.0 at aa 67-86
862962004222	Signal peptide predicted for BF638R1025 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.466 between residues 19 and 20
862962004223	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
862962004224	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
862962004225	homodimer interface [polypeptide binding]; other site
862962004226	metal binding site [ion binding]; metal-binding site
862962004227	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
862962004228	homodimer interface [polypeptide binding]; other site
862962004229	active site
862962004230	putative chemical substrate binding site [chemical binding]; other site
862962004231	metal binding site [ion binding]; metal-binding site
862962004232	HMMPfam hit to PF03819, MazG nucleotide pyrophosphohydrolase domain, score 2.6e-39
862962004233	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
862962004234	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962004235	3 probable transmembrane helices predicted for BF638R1027 by TMHMM2.0 at aa 7-29, 51-73 and 93-110
862962004236	Signal peptide predicted for BF638R1027 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 30 and 31
862962004237	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
862962004238	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
862962004239	HIGH motif; other site
862962004240	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
862962004241	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
862962004242	active site
862962004243	KMSKS motif; other site
862962004244	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
862962004245	tRNA binding surface [nucleotide binding]; other site
862962004246	anticodon binding site; other site
862962004247	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
862962004248	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 2.8e-206
862962004249	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962004250	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962004251	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962004252	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962004253	dimer interface [polypeptide binding]; other site
862962004254	phosphorylation site [posttranslational modification]
862962004255	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962004256	ATP binding site [chemical binding]; other site
862962004257	Mg2+ binding site [ion binding]; other site
862962004258	G-X-G motif; other site
862962004259	Signal peptide predicted for BF638R1029 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.913 between residues 27 and 28
862962004260	1 probable transmembrane helix predicted for BF638R1029 by TMHMM2.0 at aa 368-390
862962004261	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.9e-22
862962004262	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3e-38
862962004263	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962004264	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962004265	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962004266	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962004267	DNA binding residues [nucleotide binding]
862962004268	HMMPfam hit to PF04542, Sigma-70 region, score 0.01
862962004269	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962004270	FecR protein; Region: FecR; pfam04773
862962004271	HMMPfam hit to PF04773, FecR protein, score 1.7e-28
862962004272	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962004273	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962004274	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962004275	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962004276	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962004277	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962004278	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 5.7e-08
862962004279	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.8e-15
862962004280	HMMPfam hit to PF00593, TonB dependent receptor, score 1.8e-12
862962004281	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
862962004282	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962004283	Signal peptide predicted for BF638R1036 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.332 between residues 19 and 20
862962004284	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004285	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962004286	putative catalytic site [active]
862962004287	putative metal binding site [ion binding]; other site
862962004288	putative phosphate binding site [ion binding]; other site
862962004289	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962004290	putative catalytic site [active]
862962004291	putative phosphate binding site [ion binding]; other site
862962004292	putative metal binding site [ion binding]; other site
862962004293	Signal peptide predicted for BF638R1037 by SignalP 2.0 HMM (Signal peptide probability 0.886) with cleavage site probability 0.726 between residues 20 and 21
862962004294	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.2e-11
862962004295	Bacillus subtilis YvnB and related proteins, metallophosphatase domain; Region: MPP_YvnB; cd07399
862962004296	putative active site [active]
862962004297	putative metal binding site [ion binding]; other site
862962004298	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962004299	Signal peptide predicted for BF638R1038 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.977 between residues 35 and 36
862962004300	1 probable transmembrane helix predicted for BF638R1038 by TMHMM2.0 at aa 20-42
862962004301	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962004302	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962004303	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962004304	DNA binding residues [nucleotide binding]
862962004305	HMMPfam hit to PF04545, Sigma-70, region, score 5.7e-12
862962004306	HMMPfam hit to PF04542, Sigma-70 region, score 6.7e-06
862962004307	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962004308	FecR protein; Region: FecR; pfam04773
862962004309	1 probable transmembrane helix predicted for BF638R1040 by TMHMM2.0 at aa 82-104
862962004310	HMMPfam hit to PF04773, FecR protein, score 8.6e-28
862962004311	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962004312	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962004313	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962004314	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962004315	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962004316	Signal peptide predicted for BF638R1041 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.958 between residues 44 and 45
862962004317	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 7.8e-07
862962004318	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.8e-21
862962004319	HMMPfam hit to PF00593, TonB dependent receptor, score 2.9e-16
862962004320	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962004321	Signal peptide predicted for BF638R1042 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.993 between residues 19 and 20
862962004322	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004323	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962004324	Sulfatase; Region: Sulfatase; cl17466
862962004325	Signal peptide predicted for BF638R1043 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.691 between residues 18 and 19
862962004326	HMMPfam hit to PF00884, Sulfatase, score 4e-32
862962004327	PS00523 Sulfatases signature 1.
862962004328	PS00149 Sulfatases signature 2.
862962004329	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962004330	Sulfatase; Region: Sulfatase; pfam00884
862962004331	Signal peptide predicted for BF638R1045 by SignalP 2.0 HMM (Signal peptide probability 0.950) with cleavage site probability 0.861 between residues 48 and 49
862962004332	HMMPfam hit to PF00884, Sulfatase, score 7.6e-36
862962004333	PS00523 Sulfatases signature 1.
862962004334	PS00149 Sulfatases signature 2.
862962004335	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004336	HMMPfam hit to PF07719, no description, score 1.7
862962004337	HMMPfam hit to PF07719, no description, score 2.9
862962004338	Signal peptide predicted for BF638R1047 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.871 between residues 21 and 22
862962004339	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004340	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
862962004341	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
862962004342	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962004343	nucleotide binding region [chemical binding]; other site
862962004344	ATP-binding site [chemical binding]; other site
862962004345	SEC-C motif; Region: SEC-C; pfam02810
862962004346	HMMPfam hit to PF02810, SEC-C motif, score 3.6e-10
862962004347	HMMPfam hit to PF07516, SecA Wing and Scaffold domain, score 6.2e-35
862962004348	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0042
862962004349	PS01312 Protein secA signatures.
862962004350	HMMPfam hit to PF07517, SecA DEAD-like domain, score 1.9e-111
862962004351	HMMPfam hit to PF01043, SecA preprotein cross-linking domain, score 1.2e-17
862962004352	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
862962004353	HMMPfam hit to PF01663, Type I phosphodiesterase / nucleotide py, score 7.6e-07
862962004354	Signal peptide predicted for BF638R1049 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.991 between residues 19 and 20
862962004355	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
862962004356	5 probable transmembrane helices predicted for BF638R1050 by TMHMM2.0 at aa 270-292, 299-321, 331-348, 361-378 and 383-402
862962004357	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004358	Signal peptide predicted for BF638R1050 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.529 between residues 22 and 23
862962004359	pantothenate kinase; Reviewed; Region: PRK13320
862962004360	HMMPfam hit to PF03309, Bordetella pertussis Bvg accessory fac, score 1.5e-24
862962004361	Signal peptide predicted for BF638R1054 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 23 and 24
862962004362	Signal peptide predicted for BF638R1055 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 21 and 22
862962004363	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.15
862962004364	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.45
862962004365	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
862962004366	Signal peptide predicted for BF638R1056 by SignalP 2.0 HMM (Signal peptide probability 0.813) with cleavage site probability 0.747 between residues 53 and 54
862962004367	1 probable transmembrane helix predicted for BF638R1056 by TMHMM2.0 at aa 21-43
862962004368	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004369	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
862962004370	Domain of unknown function DUF21; Region: DUF21; pfam01595
862962004371	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
862962004372	Transporter associated domain; Region: CorC_HlyC; smart01091
862962004373	Signal peptide predicted for BF638R1057 by SignalP 2.0 HMM (Signal peptide probability 0.932) with cleavage site probability 0.659 between residues 23 and 24
862962004374	HMMPfam hit to PF01595, Domain of unknown function DUF21, score 4.8e-25
862962004375	4 probable transmembrane helices predicted for BF638R1057 by TMHMM2.0 at aa 5-27, 55-77, 87-109 and 121-143
862962004376	HMMPfam hit to PF00571, CBS domain, score 1.7e-08
862962004377	HMMPfam hit to PF00571, CBS domain, score 3.3e-07
862962004378	HMMPfam hit to PF03471, Transporter associated domain, score 4.2e-19
862962004379	SurA N-terminal domain; Region: SurA_N_2; pfam13623
862962004380	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
862962004381	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
862962004382	Signal peptide predicted for BF638R1058 by SignalP 2.0 HMM (Signal peptide probability 0.913) with cleavage site probability 0.447 between residues 27 and 28
862962004383	1 probable transmembrane helix predicted for BF638R1058 by TMHMM2.0 at aa 13-31
862962004384	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14466
862962004385	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962004386	FeS/SAM binding site; other site
862962004387	HMMPfam hit to PF04055, Radical SAM superfamily, score 2.5e-18
862962004388	Signal peptide predicted for BF638R1061 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.323 between residues 55 and 56
862962004389	1 probable transmembrane helix predicted for BF638R1061 by TMHMM2.0 at aa 23-37
862962004390	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004391	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
862962004392	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
862962004393	HMMPfam hit to PF04166, Pyridoxal phosphate biosynthetic protein Pdx, score 7.2e-97
862962004394	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962004395	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
862962004396	Walker A motif; other site
862962004397	ATP binding site [chemical binding]; other site
862962004398	Walker B motif; other site
862962004399	arginine finger; other site
862962004400	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962004401	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.9e-143
862962004402	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
862962004403	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
862962004404	PS00688 Sigma-54 interaction domain C-terminal part signature.
862962004405	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 6.3e-16
862962004406	Lipopolysaccharide-assembly; Region: LptE; pfam04390
862962004407	Signal peptide predicted for BF638R1064 by SignalP 2.0 HMM (Signal peptide probability 0.791) with cleavage site probability 0.454 between residues 28 and 29
862962004408	1 probable transmembrane helix predicted for BF638R1064 by TMHMM2.0 at aa 10-32
862962004409	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004410	Preprotein translocase SecG subunit; Region: SecG; pfam03840
862962004411	Signal peptide predicted for BF638R1066 by SignalP 2.0 HMM (Signal peptide probability 0.880) with cleavage site probability 0.275 between residues 27 and 28
862962004412	2 probable transmembrane helices predicted for BF638R1066 by TMHMM2.0 at aa 2-24 and 53-75
862962004413	HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 6.3e-15
862962004414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962004415	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962004416	putative substrate translocation pore; other site
862962004417	Signal peptide predicted for BF638R1067 by SignalP 2.0 HMM (Signal peptide probability 0.818) with cleavage site probability 0.768 between residues 34 and 35
862962004418	12 probable transmembrane helices predicted for BF638R1067 by TMHMM2.0 at aa 17-34, 57-79, 86-108, 123-145, 166-188, 198-220, 255-277, 292-314, 321-343, 348-370, 383-405 and 425-444
862962004419	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.6e-24
862962004420	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004421	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
862962004422	Signal peptide predicted for BF638R1069 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 18 and 19
862962004423	putative carbohydrate kinase; Provisional; Region: PRK10565
862962004424	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
862962004425	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
862962004426	putative substrate binding site [chemical binding]; other site
862962004427	putative ATP binding site [chemical binding]; other site
862962004428	HMMPfam hit to PF01256, Carbohydrate kinase, score 3e-58
862962004429	PS01050 Uncharacterized protein family UPF0031 signature 2.
862962004430	HMMPfam hit to PF03853, YjeF-related protein N-terminus, score 4.8e-34
862962004431	12 probable transmembrane helices predicted for BF638R1071 by TMHMM2.0 at aa 19-38, 53-71, 91-110, 115-137, 144-166, 176-198, 225-247, 267-289, 296-315, 325-347, 359-381 and 396-418
862962004432	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004433	Signal peptide predicted for BF638R1071 by SignalP 2.0 HMM (Signal peptide probability 0.708) with cleavage site probability 0.453 between residues 37 and 38
862962004434	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962004435	S-adenosylmethionine binding site [chemical binding]; other site
862962004436	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004437	similar to PS_8/PS_C non-variable operon; lipopolysaccharide biosynthesis locus in BF9343
862962004438	Transcription antiterminator [Transcription]; Region: NusG; COG0250
862962004439	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962004440	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962004441	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 5.5e-70
862962004442	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962004443	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962004444	substrate binding site; other site
862962004445	tetramer interface; other site
862962004446	HMMPfam hit to PF00483, Nucleotidyl transferase, score 4.5e-108
862962004447	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962004448	14 probable transmembrane helices predicted for BF638R1077 by TMHMM2.0 at aa 13-35, 45-67, 88-110, 130-152, 173-195, 205-227, 239-261, 267-289, 314-336, 346-368, 381-400, 405-424, 437-459 and 469-491
862962004449	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004450	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
862962004451	1 probable transmembrane helix predicted for BF638R1079 by TMHMM2.0 at aa 28-47
862962004452	O-antigen polysaccharide polymerase Wzy; Region: O-ag_pol_Wzy; pfam14296
862962004453	12 probable transmembrane helices predicted for BF638R1080 by TMHMM2.0 at aa 20-39, 49-71, 78-100, 120-142, 163-185, 205-224, 231-248, 252-269, 276-298, 395-417, 430-447 and 452-471
862962004454	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
862962004455	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
862962004456	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
862962004457	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 7.4e-59
862962004458	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
862962004459	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 6.8e-35
862962004460	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 1.1e-14
862962004461	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962004462	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962004463	active site
862962004464	homodimer interface [polypeptide binding]; other site
862962004465	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1.6e-164
862962004466	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962004467	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962004468	HMMPfam hit to PF00534, Glycosyl transferases group, score 4.5e-05
862962004469	WxcM-like, C-terminal; Region: FdtA; pfam05523
862962004470	HMMPfam hit to PF05523, WxcM-like, C-terminal, score 2.8e-88
862962004471	WxcM-like, C-terminal; Region: FdtA; pfam05523
862962004472	HMMPfam hit to PF05523, WxcM-like, C-terminal, score 1.1e-90
862962004473	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
862962004474	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962004475	inhibitor-cofactor binding pocket; inhibition site
862962004476	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962004477	catalytic residue [active]
862962004478	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 6e-125
862962004479	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
862962004480	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
862962004481	NAD(P) binding site [chemical binding]; other site
862962004482	homodimer interface [polypeptide binding]; other site
862962004483	substrate binding site [chemical binding]; other site
862962004484	active site
862962004485	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
862962004486	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 2.2e-10
862962004487	capsular polysaccharide assembling protein (CAPF) like, extended (e) SDRs; Region: CAPF_like_SDR_e; cd05261
862962004488	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
862962004489	putative NAD(P) binding site [chemical binding]; other site
862962004490	active site
862962004491	putative substrate binding site [chemical binding]; other site
862962004492	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
862962004493	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962004494	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962004495	active site
862962004496	homodimer interface [polypeptide binding]; other site
862962004497	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1.4e-104
862962004498	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962004499	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
862962004500	HMMPfam hit to PF00534, Glycosyl transferases group, score 0.00021
862962004501	Bacterial sugar transferase; Region: Bac_transf; pfam02397
862962004502	HMMPfam hit to PF02397, Bacterial sugar transferase, score 2e-46
862962004503	1 probable transmembrane helix predicted for BF638R1092 by TMHMM2.0 at aa 13-35
862962004504	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
862962004505	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
862962004506	putative trimer interface [polypeptide binding]; other site
862962004507	putative CoA binding site [chemical binding]; other site
862962004508	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 13
862962004509	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 7.7
862962004510	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.4
862962004511	PS00101 Hexapeptide-repeat containing-transferases signature.
862962004512	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1
862962004513	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
862962004514	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962004515	inhibitor-cofactor binding pocket; inhibition site
862962004516	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962004517	catalytic residue [active]
862962004518	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.2e-113
862962004519	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
862962004520	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
862962004521	Poxvirus serine/threonine protein kinase; Region: Pox_ser-thr_kin; cl17825
862962004522	HMMPfam hit to PF03929, PepSY-associated TM helix, score 11
862962004523	4 probable transmembrane helices predicted for BF638R1098 by TMHMM2.0 at aa 12-29, 212-234, 255-277 and 471-490
862962004524	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.044
862962004525	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.03
862962004526	Signal peptide predicted for BF638R1098 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.891 between residues 31 and 32
862962004527	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.00031
862962004528	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
862962004529	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004530	Signal peptide predicted for BF638R1099 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.596 between residues 24 and 25
862962004531	1 probable transmembrane helix predicted for BF638R1099 by TMHMM2.0 at aa 7-24
862962004532	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
862962004533	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962004534	N-terminal plug; other site
862962004535	ligand-binding site [chemical binding]; other site
862962004536	HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-22
862962004537	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.5e-23
862962004538	Signal peptide predicted for BF638R1100 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.867 between residues 20 and 21
862962004539	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962004540	active site
862962004541	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.8e-16
862962004542	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
862962004543	adenylate kinase; Reviewed; Region: adk; PRK00279
862962004544	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
862962004545	AMP-binding site [chemical binding]; other site
862962004546	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
862962004547	HMMPfam hit to PF00406, Adenylate kinase, score 4.3e-77
862962004548	PS00113 Adenylate kinase signature.
862962004549	GTPase CgtA; Reviewed; Region: obgE; PRK12298
862962004550	GTP1/OBG; Region: GTP1_OBG; pfam01018
862962004551	Obg GTPase; Region: Obg; cd01898
862962004552	G1 box; other site
862962004553	GTP/Mg2+ binding site [chemical binding]; other site
862962004554	Switch I region; other site
862962004555	G2 box; other site
862962004556	G3 box; other site
862962004557	Switch II region; other site
862962004558	G4 box; other site
862962004559	G5 box; other site
862962004560	HMMPfam hit to PF01018, GTP1/OBG, score 2e-64
862962004561	HMMPfam hit to PF01926, GTPase of unknown function, score 1.2e-41
862962004562	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004563	PS00905 GTP1/OBG family signature.
862962004564	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
862962004565	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
862962004566	HMMPfam hit to PF02578, Uncharacterised ACR, YfiH family COG1496, score 1.5e-46
862962004567	B3/4 domain; Region: B3_4; smart00873
862962004568	B3/4 domain; Region: B3_4; pfam03483
862962004569	HMMPfam hit to PF03483, B3/4 domain, score 1.4e-07
862962004570	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
862962004571	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962004572	Signal peptide predicted for BF638R1107 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.298 between residues 25 and 26
862962004573	HMMPfam hit to PF01551, Peptidase family M23, score 1.8e-35
862962004574	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
862962004575	Signal peptide predicted for BF638R1108 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.782 between residues 19 and 20
862962004576	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
862962004577	Signal peptide predicted for BF638R1109 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.831 between residues 25 and 26
862962004578	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004580	HMMPfam hit to PF07494, Two component regulator propeller, score 50
862962004581	HMMPfam hit to PF07494, Two component regulator propeller, score 0.018
862962004582	HMMPfam hit to PF07494, Two component regulator propeller, score 6.1
862962004583	HMMPfam hit to PF07494, Two component regulator propeller, score 29
862962004584	HMMPfam hit to PF07495, Two component regulator three Y motif, score 0.00012
862962004585	1 probable transmembrane helix predicted for BF638R1112 by TMHMM2.0 at aa 702-724
862962004586	HMMPfam hit to PF00072, Response regulator receiver domain, score 2e-05
862962004587	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 5.7e-08
862962004588	PS00041 Bacterial regulatory proteins, araC family signature.
862962004589	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.9e-09
862962004590	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
862962004591	active site
862962004592	DNA polymerase IV; Validated; Region: PRK02406
862962004593	DNA binding site [nucleotide binding]
862962004594	HMMPfam hit to PF00817, impB/mucB/samB family, score 6.8e-103
862962004595	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004596	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
862962004597	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
862962004598	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
862962004599	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
862962004600	HMMPfam hit to PF01841, Transglutaminase-like superfamily, score 6.6e-08
862962004601	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004602	Predicted membrane protein [Function unknown]; Region: COG1288
862962004603	12 probable transmembrane helices predicted for BF638R1117 by TMHMM2.0 at aa 5-27, 119-141, 146-163, 170-192, 207-229, 266-288, 293-315, 322-339, 343-362, 382-399, 421-443 and 504-526
862962004604	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.2e-84
862962004605	Signal peptide predicted for BF638R1119 by SignalP 2.0 HMM (Signal peptide probability 0.890) with cleavage site probability 0.435 between residues 17 and 18
862962004606	1 probable transmembrane helix predicted for BF638R1119 by TMHMM2.0 at aa 5-24
862962004607	Signal peptide predicted for BF638R1121 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.546 between residues 32 and 33
862962004608	1 probable transmembrane helix predicted for BF638R1121 by TMHMM2.0 at aa 4-26
862962004609	Signal peptide predicted for BF638R1122 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.621 between residues 28 and 29
862962004610	1 probable transmembrane helix predicted for BF638R1122 by TMHMM2.0 at aa 4-26
862962004611	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
862962004612	9 probable transmembrane helices predicted for BF638R1123 by TMHMM2.0 at aa 20-42, 49-68, 100-122, 135-157, 188-210, 242-264, 284-306, 313-335 and 379-401
862962004613	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacet, score 1.8e-21
862962004614	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004615	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004616	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
862962004617	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
862962004618	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
862962004619	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
862962004620	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
862962004621	shikimate binding site; other site
862962004622	NAD(P) binding site [chemical binding]; other site
862962004623	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 1.2e-64
862962004624	HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate sy, score 2.4e-109
862962004625	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
862962004626	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962004627	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962004628	HMMPfam hit to PF02311, AraC-like ligand binding domain, score 0.0017
862962004629	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.29
862962004630	PS00041 Bacterial regulatory proteins, araC family signature.
862962004631	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 7.4e-11
862962004632	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
862962004633	Signal peptide predicted for BF638R1127 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23
862962004634	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
862962004635	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962004636	Coenzyme A binding pocket [chemical binding]; other site
862962004637	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
862962004638	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962004639	Coenzyme A binding pocket [chemical binding]; other site
862962004640	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.5e-12
862962004641	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 8.6e-15
862962004642	TPR/MLP1/MLP2-like protein; Region: TPR_MLP1_2; pfam07926
862962004643	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
862962004644	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
862962004645	active site
862962004646	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 9.1e-52
862962004647	Restriction endonuclease [Defense mechanisms]; Region: COG3587
862962004648	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
862962004649	ATP binding site [chemical binding]; other site
862962004650	putative Mg++ binding site [ion binding]; other site
862962004651	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.2e-06
862962004652	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
862962004653	DNA methylase; Region: N6_N4_Mtase; pfam01555
862962004654	DNA methylase; Region: N6_N4_Mtase; cl17433
862962004655	HMMPfam hit to PF01555, DNA methylase, score 4.1e-06
862962004656	PS00092 N-6 Adenine-specific DNA methylases signature.
862962004657	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
862962004658	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
862962004659	CPE1046 is an uncharacterized Clostridium perfringens protein with a glycosyl hydrolase family 31 (GH31) domain. The domain architecture of CPE1046 and its orthologs includes a C-terminal fibronectin type 3 (FN3) domain and a coagulation factor 5/8 type...; Region: GH31_CPE1046; cd06596
862962004660	putative active site [active]
862962004661	putative catalytic site [active]
862962004662	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962004663	Interdomain contacts; other site
862962004664	Cytokine receptor motif; other site
862962004665	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962004666	Domains similar to the eukaryotic reeler domain and bacterial cohesins; Region: Reeler_cohesin_like; cl14606
862962004667	Signal peptide predicted for BF638R1132 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.872 between residues 31 and 32
862962004668	1 probable transmembrane helix predicted for BF638R1132 by TMHMM2.0 at aa 13-32
862962004669	HMMPfam hit to PF01055, Glycosyl hydrolases family, score 7.1e-67
862962004670	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.002
862962004671	HMMPfam hit to PF00754, F5/8 type C domain, score 6.8e-14
862962004672	PS00018 EF-hand calcium-binding domain.
862962004673	PS00018 EF-hand calcium-binding domain.
862962004674	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962004675	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
862962004676	NAD(P) binding site [chemical binding]; other site
862962004677	active site
862962004678	HMMPfam hit to PF00106, short chain dehydrogenase, score 4.5e-57
862962004679	PS00061 Short-chain dehydrogenases/reductases family signature.
862962004680	Prophage
862962004681	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
862962004682	non-specific DNA binding site [nucleotide binding]; other site
862962004683	salt bridge; other site
862962004684	sequence-specific DNA binding site [nucleotide binding]; other site
862962004685	HipA N-terminal domain; Region: Couple_hipA; pfam13657
862962004686	HipA-like N-terminal domain; Region: HipA_N; pfam07805
862962004687	HipA-like C-terminal domain; Region: HipA_C; pfam07804
862962004688	HMMPfam hit to PF07805, HipA-like N-terminal domain, score 7.2e-18
862962004689	HMMPfam hit to PF07804, HipA-like C-terminal domain, score 2.3e-22
862962004690	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
862962004691	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
862962004692	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962004693	non-specific DNA binding site [nucleotide binding]; other site
862962004694	salt bridge; other site
862962004695	sequence-specific DNA binding site [nucleotide binding]; other site
862962004696	HMMPfam hit to PF01381, Helix-turn-helix, score 5.3e-07
862962004697	AAA domain; Region: AAA_22; pfam13401
862962004698	AAA domain; Region: AAA_14; pfam13173
862962004699	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
862962004700	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
862962004701	HMMPfam hit to PF01637, Archaeal ATPase, score 3.3e-30
862962004702	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004703	HMMPfam hit to PF03008, Archaea bacterial proteins of unknown fun, score 0.00025
862962004704	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
862962004705	2 probable transmembrane helices predicted for BF638R1140 by TMHMM2.0 at aa 656-678 and 690-712
862962004706	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
862962004707	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962004708	salt bridge; other site
862962004709	non-specific DNA binding site [nucleotide binding]; other site
862962004710	sequence-specific DNA binding site [nucleotide binding]; other site
862962004711	HMMPfam hit to PF01381, Helix-turn-helix, score 3.2e-10
862962004712	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
862962004713	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
862962004714	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962004715	ATP binding site [chemical binding]; other site
862962004716	putative Mg++ binding site [ion binding]; other site
862962004717	HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 5.3e-36
862962004718	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.4e-44
862962004719	T5orf172 domain; Region: T5orf172; pfam10544
862962004720	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
862962004721	HsdM N-terminal domain; Region: HsdM_N; pfam12161
862962004722	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962004723	S-adenosylmethionine binding site [chemical binding]; other site
862962004724	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
862962004725	HMMPfam hit to PF02506, Type I restriction modification system, M, score 1.6e-72
862962004726	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004727	PS00092 N-6 Adenine-specific DNA methylases signature.
862962004728	HMMPfam hit to PF02384, N-6 DNA Methylase, score 8.4e-77
862962004729	Virulence protein [General function prediction only]; Region: COG3943
862962004730	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
862962004731	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
862962004732	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
862962004733	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
862962004734	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
862962004735	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
862962004736	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
862962004737	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.2e-24
862962004738	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 3.1e-29
862962004739	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962004740	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
862962004741	Int/Topo IB signature motif; other site
862962004742	HMMPfam hit to PF00589, Phage integrase family, score 2.7e-25
862962004743	Signal peptide predicted for BF638R1151 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.971 between residues 39 and 40; Signal peptide predicted for BF638R1152 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.972 between residues 32 and 33
862962004744	1 probable transmembrane helix predicted for BF638R1151 by TMHMM2.0 at aa 12-34; 1 probable transmembrane helix predicted for BF638R1152 by TMHMM2.0 at aa 5-27
862962004745	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004746	2 probable transmembrane helices predicted for BF638R1153 by TMHMM2.0 at aa 117-139 and 149-171
862962004747	AAA domain; Region: AAA_25; pfam13481
862962004748	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004749	2 probable transmembrane helices predicted for BF638R1158 by TMHMM2.0 at aa 23-42 and 52-74
862962004750	Signal peptide predicted for BF638R1158 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.437 between residues 35 and 36
862962004751	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962004752	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962004753	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
862962004754	Int/Topo IB signature motif; other site
862962004755	HMMPfam hit to PF00589, Phage integrase family, score 8.3e-13
862962004756	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
862962004757	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004758	Helix-turn-helix domain; Region: HTH_17; cl17695
862962004759	1 probable transmembrane helix predicted for BF638R1161 by TMHMM2.0 at aa 53-75
862962004760	SIR2-like domain; Region: SIR2_2; pfam13289
862962004761	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962004762	non-specific DNA binding site [nucleotide binding]; other site
862962004763	salt bridge; other site
862962004764	sequence-specific DNA binding site [nucleotide binding]; other site
862962004765	HMMPfam hit to PF01381, Helix-turn-helix, score 5.7e-10
862962004766	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
862962004767	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
862962004768	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962004769	ATP binding site [chemical binding]; other site
862962004770	putative Mg++ binding site [ion binding]; other site
862962004771	HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 2.6e-23
862962004772	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962004773	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.9e-21
862962004774	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
862962004775	HMMPfam hit to PF02506, Type I restriction modification system, M, score 3e-06
862962004776	PS00092 N-6 Adenine-specific DNA methylases signature.
862962004777	HMMPfam hit to PF02384, N-6 DNA Methylase, score 6.6e-40
862962004778	Virulence protein [General function prediction only]; Region: COG3943
862962004779	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
862962004780	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
862962004781	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
862962004782	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
862962004783	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 4.8e-22
862962004784	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.7e-21
862962004785	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
862962004786	PS00591 Glycosyl hydrolases family 10 active site.
862962004787	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
862962004788	BRO family, N-terminal domain; Region: Bro-N; pfam02498
862962004789	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962004790	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
862962004791	active site
862962004792	Int/Topo IB signature motif; other site
862962004793	DNA binding site [nucleotide binding]
862962004794	HMMPfam hit to PF00589, Phage integrase family, score 1.3e-26
862962004795	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 0.042
862962004796	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
862962004797	HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 8.2e-71
862962004798	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
862962004799	HMMPfam hit to PF05713, Bacterial mobilisation protein (MobC), score 2.2e-11
862962004800	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
862962004801	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004802	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
862962004803	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962004804	putative active site [active]
862962004805	putative NTP binding site [chemical binding]; other site
862962004806	putative nucleic acid binding site [nucleotide binding]; other site
862962004807	2 probable transmembrane helices predicted for BF638R1181 by TMHMM2.0 at aa 9-31 and 41-58
862962004808	Virulence protein [General function prediction only]; Region: COG3943
862962004809	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962004810	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962004811	Int/Topo IB signature motif; other site
862962004812	HMMPfam hit to PF00589, Phage integrase family, score 4.2e-16
862962004813	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004814	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004815	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
862962004816	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
862962004817	trmE is a tRNA modification GTPase; Region: trmE; cd04164
862962004818	G1 box; other site
862962004819	GTP/Mg2+ binding site [chemical binding]; other site
862962004820	Switch I region; other site
862962004821	G2 box; other site
862962004822	Switch II region; other site
862962004823	G3 box; other site
862962004824	G4 box; other site
862962004825	G5 box; other site
862962004826	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
862962004827	HMMPfam hit to PF01926, GTPase of unknown function, score 8.3e-38
862962004828	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004829	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
862962004830	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962004831	dimer interface [polypeptide binding]; other site
862962004832	phosphorylation site [posttranslational modification]
862962004833	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962004834	ATP binding site [chemical binding]; other site
862962004835	Mg2+ binding site [ion binding]; other site
862962004836	G-X-G motif; other site
862962004837	Response regulator receiver domain; Region: Response_reg; pfam00072
862962004838	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962004839	active site
862962004840	phosphorylation site [posttranslational modification]
862962004841	intermolecular recognition site; other site
862962004842	dimerization interface [polypeptide binding]; other site
862962004843	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.2e-25
862962004844	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.3e-37
862962004845	HMMPfam hit to PF00072, Response regulator receiver domain, score 3.6e-24
862962004846	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
862962004847	NADH(P)-binding; Region: NAD_binding_10; pfam13460
862962004848	NAD binding site [chemical binding]; other site
862962004849	substrate binding site [chemical binding]; other site
862962004850	putative active site [active]
862962004851	Signal peptide predicted for BF638R1187 by SignalP 2.0 HMM (Signal peptide probability 0.846) with cleavage site probability 0.454 between residues 18 and 19
862962004852	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
862962004853	active site
862962004854	catalytic site [active]
862962004855	substrate binding site [chemical binding]; other site
862962004856	HMMPfam hit to PF00929, Exonuclease, score 1.2e-09
862962004857	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
862962004858	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
862962004859	HMMPfam hit to PF01048, Phosphorylase family, score 8.4e-11
862962004860	hypothetical protein; Provisional; Region: PRK13665
862962004861	HMMPfam hit to PF07251, Protein of unknown function (DUF1432), score 1.3e-247
862962004862	1 probable transmembrane helix predicted for BF638R1190 by TMHMM2.0 at aa 7-29
862962004863	3 probable transmembrane helices predicted for BF638R1191 by TMHMM2.0 at aa 4-23, 25-47 and 51-73
862962004864	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004865	Signal peptide predicted for BF638R1191 by SignalP 2.0 HMM (Signal peptide probability 0.932) with cleavage site probability 0.905 between residues 30 and 31
862962004866	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962004867	binding surface
862962004868	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962004869	TPR motif; other site
862962004870	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962004871	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.3e-05
862962004872	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.85
862962004873	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.1
862962004874	Signal peptide predicted for BF638R1192 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.901 between residues 22 and 23
862962004875	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
862962004876	Ligand Binding Site [chemical binding]; other site
862962004877	TIGR00269 family protein; Region: TIGR00269
862962004878	Protein of unknown function, DUF486; Region: DUF486; cl01236
862962004879	HMMPfam hit to PF04342, Protein of unknown function, DUF486, score 3.6e-41
862962004880	4 probable transmembrane helices predicted for BF638R1194 by TMHMM2.0 at aa 4-25, 32-54, 74-96 and 103-121
862962004881	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
862962004882	ApbE family; Region: ApbE; pfam02424
862962004883	HMMPfam hit to PF02424, ApbE family, score 4.9e-64
862962004884	Signal peptide predicted for BF638R1196 by SignalP 2.0 HMM (Signal peptide probability 0.679) with cleavage site probability 0.284 between residues 35 and 36
862962004885	Signal peptide predicted for BF638R1195 by SignalP 2.0 HMM (Signal peptide probability 0.727) with cleavage site probability 0.301 between residues 34 and 35
862962004886	1 probable transmembrane helix predicted for BF638R1195 by TMHMM2.0 at aa 16-33; 1 probable transmembrane helix predicted for BF638R1196 by TMHMM2.0 at aa 17-34
862962004887	Predicted membrane protein [Function unknown]; Region: COG1971
862962004888	Domain of unknown function DUF; Region: DUF204; pfam02659
862962004889	Domain of unknown function DUF; Region: DUF204; pfam02659
862962004890	6 probable transmembrane helices predicted for BF638R1197 by TMHMM2.0 at aa 6-28, 35-57, 67-85, 98-120, 135-157 and 170-192
862962004891	HMMPfam hit to PF02659, Domain of unknown function DUF, score 1.9e-12
862962004892	HMMPfam hit to PF02659, Domain of unknown function DUF, score 7.8e-13
862962004893	Signal peptide predicted for BF638R1199 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.552 between residues 26 and 27
862962004894	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004895	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
862962004896	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
862962004897	Ligand binding site; other site
862962004898	Putative Catalytic site; other site
862962004899	DXD motif; other site
862962004900	3 probable transmembrane helices predicted for BF638R1200 by TMHMM2.0 at aa 209-231, 236-258 and 278-300
862962004901	HMMPfam hit to PF00535, Glycosyl transferase, score 1.1e-31
862962004902	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
862962004903	3 probable transmembrane helices predicted for BF638R1201 by TMHMM2.0 at aa 21-40, 44-66 and 86-108
862962004904	enolase; Provisional; Region: eno; PRK00077
862962004905	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
862962004906	dimer interface [polypeptide binding]; other site
862962004907	metal binding site [ion binding]; metal-binding site
862962004908	substrate binding pocket [chemical binding]; other site
862962004909	HMMPfam hit to PF00113, Enolase, C-terminal TIM barrel domain, score 4.7e-170
862962004910	PS00164 Enolase signature.
862962004911	HMMPfam hit to PF03952, Enolase, N-terminal domain, score 1.1e-67
862962004912	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
862962004913	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
862962004914	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
862962004915	HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.04
862962004916	HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.88
862962004917	HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.0063
862962004918	camphor resistance protein CrcB; Provisional; Region: PRK14210
862962004919	HMMPfam hit to PF02537, CrcB-like protein, score 6.3e-29
862962004920	4 probable transmembrane helices predicted for BF638R1204 by TMHMM2.0 at aa 5-25, 35-57, 64-86 and 101-123
862962004921	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
862962004922	Signal peptide predicted for BF638R1205 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 30 and 31
862962004923	1 probable transmembrane helix predicted for BF638R1205 by TMHMM2.0 at aa 13-35
862962004924	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
862962004925	non-specific DNA binding site [nucleotide binding]; other site
862962004926	salt bridge; other site
862962004927	sequence-specific DNA binding site [nucleotide binding]; other site
862962004928	HMMPfam hit to PF01381, Helix-turn-helix, score 0.00013
862962004929	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
862962004930	Signal peptide predicted for BF638R1207 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.521 between residues 36 and 37
862962004931	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962004932	Signal peptide predicted for BF638R1208 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.933 between residues 21 and 22
862962004933	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
862962004934	RNA binding surface [nucleotide binding]; other site
862962004935	HMMPfam hit to PF01479, S4 domain, score 5.1e-08
862962004936	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
862962004937	putative active site [active]
862962004938	catalytic residue [active]
862962004939	HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 5e-63
862962004940	PS01195 Peptidyl-tRNA hydrolase signature 1.
862962004941	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
862962004942	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
862962004943	5S rRNA interface [nucleotide binding]; other site
862962004944	CTC domain interface [polypeptide binding]; other site
862962004945	L16 interface [polypeptide binding]; other site
862962004946	HMMPfam hit to PF01386, Ribosomal L25p family, score 2.3e-11
862962004947	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
862962004948	transcription antitermination factor NusB; Region: nusB; TIGR01951
862962004949	HMMPfam hit to PF01029, NusB family, score 1.7e-05
862962004950	Preprotein translocase subunit; Region: YajC; pfam02699
862962004951	HMMPfam hit to PF02699, Preprotein translocase subunit, score 1.4e-22
862962004952	1 probable transmembrane helix predicted for BF638R1214 by TMHMM2.0 at aa 19-36
862962004953	YbbR-like protein; Region: YbbR; pfam07949
862962004954	1 probable transmembrane helix predicted for BF638R1215 by TMHMM2.0 at aa 30-49
862962004955	HMMPfam hit to PF07949, YbbR-like protein, score 4.4e-09
862962004956	HMMPfam hit to PF07949, YbbR-like protein, score 9.2e-08
862962004957	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
862962004958	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
862962004959	CoA-binding site [chemical binding]; other site
862962004960	HMMPfam hit to PF01121, Dephospho-CoA kinase, score 2.5e-25
862962004961	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004962	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
862962004963	prophage
862962004964	PS00430 TonB-dependent receptor proteins signature 1.
862962004965	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
862962004966	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004967	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962004968	non-specific DNA binding site [nucleotide binding]; other site
862962004969	salt bridge; other site
862962004970	sequence-specific DNA binding site [nucleotide binding]; other site
862962004971	HMMPfam hit to PF01381, Helix-turn-helix, score 8.2e-10
862962004972	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
862962004973	Divergent AAA domain; Region: AAA_4; pfam04326
862962004974	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
862962004975	HMMPfam hit to PF04326, Divergent AAA domain, score 1e-08
862962004976	Ycf46; Provisional; Region: ycf46; CHL00195
862962004977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962004978	Walker B motif; other site
862962004979	arginine finger; other site
862962004980	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 7.2e-58
862962004981	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004982	AAA domain; Region: AAA_11; pfam13086
862962004983	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962004984	ATP binding site [chemical binding]; other site
862962004985	AAA domain; Region: AAA_12; pfam13087
862962004986	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004987	PS00037 Myb DNA-binding domain repeat signature 1.
862962004988	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
862962004989	HMMPfam hit to PF01076, Plasmid recombination enzyme, score 5.6e-14
862962004990	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
862962004991	PS00017 ATP/GTP-binding site motif A (P-loop).
862962004992	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962004993	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962004994	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
862962004995	active site
862962004996	DNA binding site [nucleotide binding]
862962004997	Int/Topo IB signature motif; other site
862962004998	HMMPfam hit to PF00589, Phage integrase family, score 3.9e-06
862962004999	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962005000	active site
862962005001	Int/Topo IB signature motif; other site
862962005002	DNA binding site [nucleotide binding]
862962005003	HMMPfam hit to PF00589, Phage integrase family, score 4.8e-06
862962005004	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
862962005005	Clp amino terminal domain; Region: Clp_N; pfam02861
862962005006	Clp amino terminal domain; Region: Clp_N; pfam02861
862962005007	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962005008	Walker A motif; other site
862962005009	ATP binding site [chemical binding]; other site
862962005010	Walker B motif; other site
862962005011	arginine finger; other site
862962005012	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962005013	Walker A motif; other site
862962005014	ATP binding site [chemical binding]; other site
862962005015	Walker B motif; other site
862962005016	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
862962005017	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 3.1e-109
862962005018	PS00871 Chaperonins clpA/B signature 2.
862962005019	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005020	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 2.4e-16
862962005021	PS00870 Chaperonins clpA/B signature 1.
862962005022	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005023	HMMPfam hit to PF02861, Clp amino terminal domain, score 8.5e-13
862962005024	HMMPfam hit to PF02861, Clp amino terminal domain, score 3e-06
862962005025	aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339
862962005026	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
862962005027	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
862962005028	putative dimerization interface [polypeptide binding]; other site
862962005029	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-16
862962005030	PS00044 Bacterial regulatory proteins, lysR family signature.
862962005031	HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-40
862962005032	Predicted membrane protein [Function unknown]; Region: COG2855
862962005033	Signal peptide predicted for BF638R1240 by SignalP 2.0 HMM (Signal peptide probability 0.965) with cleavage site probability 0.384 between residues 40 and 41
862962005034	11 probable transmembrane helices predicted for BF638R1240 by TMHMM2.0 at aa 16-33, 38-60, 73-95, 99-116, 128-150, 160-182, 189-211, 221-240, 247-269, 284-306 and 313-329
862962005035	HMMPfam hit to PF03601, Conserved hypothetical protein, score 5.1e-58
862962005036	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
862962005037	Signal peptide predicted for BF638R1241 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 21 and 22
862962005038	1 probable transmembrane helix predicted for BF638R1242 by TMHMM2.0 at aa 109-131
862962005039	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962005040	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962005041	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962005042	DNA binding residues [nucleotide binding]
862962005043	HMMPfam hit to PF04545, Sigma-70, region, score 1.3e-09
862962005044	HMMPfam hit to PF04542, Sigma-70 region, score 2.2e-12
862962005045	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
862962005046	hexamer interface [polypeptide binding]; other site
862962005047	RecA/RadA recombinase [DNA replication, recombination, and repair]; Region: RecA; COG0468
862962005048	Walker A motif; other site
862962005049	ATP binding site [chemical binding]; other site
862962005050	Walker B motif; other site
862962005051	HMMPfam hit to PF00154, recA bacterial DNA recombination protein, score 1.3e-229
862962005052	PS00321 recA signature.
862962005053	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005054	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
862962005055	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
862962005056	catalytic triad [active]
862962005057	HMMPfam hit to PF00578, AhpC/TSA family, score 9.5e-43
862962005058	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
862962005059	HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 1.2e-214
862962005060	Signal peptide predicted for BF638R1249 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.931 between residues 21 and 22
862962005061	META domain; Region: META; pfam03724
862962005062	META domain; Region: META; pfam03724
862962005063	Signal peptide predicted for BF638R1250 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.330 between residues 43 and 44
862962005064	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005065	HMMPfam hit to PF03724, Domain of unknown function (306), score 1e-10
862962005066	HMMPfam hit to PF03724, Domain of unknown function (306), score 6.1e-05
862962005067	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005068	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
862962005069	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
862962005070	ABC-ATPase subunit  interface; other site
862962005071	dimer interface [polypeptide binding]; other site
862962005072	putative PBP binding regions; other site
862962005073	HMMPfam hit to PF01032, FecCD transport family, score 7.2e-86
862962005074	9 probable transmembrane helices predicted for BF638R1251 by TMHMM2.0 at aa 7-29, 59-81, 94-116, 121-140, 147-169, 189-211, 237-259, 279-301 and 308-327
862962005075	Signal peptide predicted for BF638R1251 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.627 between residues 20 and 21
862962005076	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
862962005077	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
862962005078	putative ligand binding site [chemical binding]; other site
862962005079	HMMPfam hit to PF01497, Periplasmic binding protein, score 7.3e-05
862962005080	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005081	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
862962005082	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
862962005083	SLBB domain; Region: SLBB; pfam10531
862962005084	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
862962005085	SLBB domain; Region: SLBB; pfam10531
862962005086	SLBB domain; Region: SLBB; pfam10531
862962005087	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
862962005088	SLBB domain; Region: SLBB; pfam10531
862962005089	Signal peptide predicted for BF638R1254 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.796 between residues 22 and 23
862962005090	HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 1.6e-13
862962005091	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962005092	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
862962005093	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
862962005094	nucleotide binding site [chemical binding]; other site
862962005095	NEF interaction site [polypeptide binding]; other site
862962005096	SBD interface [polypeptide binding]; other site
862962005097	HMMPfam hit to PF00012, Hsp70 protein, score 0
862962005098	PS00297 Heat shock hsp70 proteins family signature 1.
862962005099	PS00329 Heat shock hsp70 proteins family signature 2.
862962005100	PS01036 Heat shock hsp70 proteins family signature 3.
862962005101	PS00043 Bacterial regulatory proteins, gntR family signature.
862962005102	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
862962005103	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
862962005104	Cl- selectivity filter; other site
862962005105	Cl- binding residues [ion binding]; other site
862962005106	pore gating glutamate residue; other site
862962005107	dimer interface [polypeptide binding]; other site
862962005108	H+/Cl- coupling transport residue; other site
862962005109	TrkA-C domain; Region: TrkA_C; pfam02080
862962005110	8 probable transmembrane helices predicted for BF638R1257 by TMHMM2.0 at aa 45-67, 82-104, 224-246, 261-283, 295-317, 332-351, 358-380 and 384-406
862962005111	HMMPfam hit to PF00654, Voltage gated chloride channel, score 1.2e-29
862962005112	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005113	endonuclease IV; Provisional; Region: PRK01060
862962005114	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
862962005115	AP (apurinic/apyrimidinic) site pocket; other site
862962005116	DNA interaction; other site
862962005117	Metal-binding active site; metal-binding site
862962005118	HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 2e-64
862962005119	PS00731 AP endonucleases family 2 signature 3.
862962005120	PS00730 AP endonucleases family 2 signature 2.
862962005121	PS00729 AP endonucleases family 2 signature 1.
862962005122	tryptophan synthase subunit beta; Reviewed; Region: PRK12391
862962005123	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
862962005124	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962005125	catalytic residue [active]
862962005126	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.5e-51
862962005127	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
862962005128	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
862962005129	14 probable transmembrane helices predicted for BF638R1260 by TMHMM2.0 at aa 21-43, 58-78, 90-107, 122-144, 157-176, 191-213, 220-242, 271-293, 305-324, 339-361, 396-415, 453-470, 517-536 and 572-593
862962005130	HMMPfam hit to PF02386, Cation transport protein, score 3.4e-50
862962005131	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
862962005132	TrkA-N domain; Region: TrkA_N; pfam02254
862962005133	HMMPfam hit to PF02254, TrkA-N domain, score 2.2e-20
862962005134	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
862962005135	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
862962005136	tetramer interface [polypeptide binding]; other site
862962005137	heme binding pocket [chemical binding]; other site
862962005138	NADPH binding site [chemical binding]; other site
862962005139	HMMPfam hit to PF00199, Catalase, score 1.3e-302
862962005140	PS00211 ABC transporters family signature.
862962005141	PS00437 Catalase proximal heme-ligand signature.
862962005142	PS00438 Catalase proximal active site signature.
862962005143	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
862962005144	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
862962005145	putative active site [active]
862962005146	putative catalytic site [active]
862962005147	HMMPfam hit to PF01055, Glycosyl hydrolases family, score 1.1e-92
862962005148	Signal peptide predicted for BF638R1264 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 23 and 24
862962005149	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962005150	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962005151	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962005152	DNA binding residues [nucleotide binding]
862962005153	HMMPfam hit to PF04542, Sigma-70 region, score 8.8e-09
862962005154	HMMPfam hit to PF04545, Sigma-70, region, score 2.2e-13
862962005155	Glycosyl hydrolase family 43, includes mostly 1,4-beta-xylanases; Region: GH43_bXyl; cd09004
862962005156	putative substrate binding site [chemical binding]; other site
862962005157	active site
862962005158	Signal peptide predicted for BF638R1266 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.882 between residues 19 and 20
862962005159	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005160	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 2.8e-51
862962005161	beta-lactamase TEM; Provisional; Region: PRK15442
862962005162	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
862962005163	HMMPfam hit to PF00144, Beta-lactamase, score 0.00012
862962005164	Signal peptide predicted for BF638R1267 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.983 between residues 33 and 34
862962005165	1 probable transmembrane helix predicted for BF638R1267 by TMHMM2.0 at aa 16-33
862962005166	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962005167	FecR protein; Region: FecR; pfam04773
862962005168	1 probable transmembrane helix predicted for BF638R1269 by TMHMM2.0 at aa 76-98
862962005169	HMMPfam hit to PF04773, FecR protein, score 1.8e-24
862962005170	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962005171	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962005172	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962005173	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962005174	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962005175	Signal peptide predicted for BF638R1270 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.977 between residues 40 and 41
862962005176	1 probable transmembrane helix predicted for BF638R1270 by TMHMM2.0 at aa 20-42
862962005177	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.1e-13
862962005178	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
862962005179	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962005180	Signal peptide predicted for BF638R1271 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.420 between residues 23 and 24
862962005181	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005182	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962005183	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962005184	putative active site [active]
862962005185	putative metal binding site [ion binding]; other site
862962005186	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962005187	Signal peptide predicted for BF638R1272 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.931 between residues 20 and 21
862962005188	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.5e-18
862962005189	Sulfatase; Region: Sulfatase; cl17466
862962005190	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
862962005191	Signal peptide predicted for BF638R1273 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 21 and 22
862962005192	1 probable transmembrane helix predicted for BF638R1273 by TMHMM2.0 at aa 5-22
862962005193	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962005194	putative catalytic site [active]
862962005195	putative metal binding site [ion binding]; other site
862962005196	putative phosphate binding site [ion binding]; other site
862962005197	PS00430 TonB-dependent receptor proteins signature 1.
862962005198	Signal peptide predicted for BF638R1274 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.555 between residues 21 and 22
862962005199	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.2e-09
862962005200	alkyl hydroperoxide reductase subunit F; Region: AhpF; TIGR03140
862962005201	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
862962005202	catalytic residue [active]
862962005203	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
862962005204	catalytic residues [active]
862962005205	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
862962005206	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962005207	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreducta, score 5.6e-66
862962005208	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
862962005209	peroxiredoxin; Region: AhpC; TIGR03137
862962005210	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
862962005211	dimer interface [polypeptide binding]; other site
862962005212	decamer (pentamer of dimers) interface [polypeptide binding]; other site
862962005213	catalytic triad [active]
862962005214	peroxidatic and resolving cysteines [active]
862962005215	HMMPfam hit to PF00578, AhpC/TSA family, score 2.2e-64
862962005216	Signal peptide predicted for BF638R1279 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 20 and 21
862962005217	Signal peptide predicted for BF638R1280 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.472 between residues 25 and 26
862962005218	1 probable transmembrane helix predicted for BF638R1280 by TMHMM2.0 at aa 4-23
862962005219	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005220	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962005221	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
862962005222	Signal peptide predicted for BF638R1281 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.996 between residues 38 and 39
862962005223	1 probable transmembrane helix predicted for BF638R1281 by TMHMM2.0 at aa 21-43
862962005224	Signal peptide predicted for BF638R1282 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.793 between residues 26 and 27
862962005225	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962005226	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962005227	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005228	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
862962005229	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
862962005230	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
862962005231	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 2.2e-106
862962005232	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 1.3e-20
862962005233	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
862962005234	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
862962005235	oligomer interface [polypeptide binding]; other site
862962005236	metal binding site [ion binding]; metal-binding site
862962005237	metal binding site [ion binding]; metal-binding site
862962005238	Cl binding site [ion binding]; other site
862962005239	aspartate ring; other site
862962005240	basic sphincter; other site
862962005241	putative hydrophobic gate; other site
862962005242	periplasmic entrance; other site
862962005243	HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 2.9e-43
862962005244	2 probable transmembrane helices predicted for BF638R1284 by TMHMM2.0 at aa 296-315 and 325-347
862962005245	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
862962005246	MutS domain III; Region: MutS_III; pfam05192
862962005247	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962005248	Walker A/P-loop; other site
862962005249	ATP binding site [chemical binding]; other site
862962005250	Q-loop/lid; other site
862962005251	ABC transporter signature motif; other site
862962005252	Walker B; other site
862962005253	D-loop; other site
862962005254	H-loop/switch region; other site
862962005255	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
862962005256	Smr domain; Region: Smr; pfam01713
862962005257	HMMPfam hit to PF01713, Smr domain, score 3e-18
862962005258	HMMPfam hit to PF00488, MutS domain V, score 4.1e-14
862962005259	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005260	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005261	Signal peptide predicted for BF638R1288 by SignalP 2.0 HMM (Signal peptide probability 0.917) with cleavage site probability 0.749 between residues 21 and 22
862962005262	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005263	Predicted permeases [General function prediction only]; Region: RarD; COG2962
862962005264	10 probable transmembrane helices predicted for BF638R1289 by TMHMM2.0 at aa 7-29, 39-56, 68-90, 94-116, 123-142, 146-168, 180-202, 212-234, 241-260 and 264-286
862962005265	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2e-13
862962005266	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005267	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.8e-10
862962005268	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962005269	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962005270	ligand binding site [chemical binding]; other site
862962005271	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 3.9e-05
862962005272	Formaldehyde dehydrogenases; Region: FDH_like; cd05278
862962005273	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
862962005274	catalytic Zn binding site [ion binding]; other site
862962005275	NAD(P) binding site [chemical binding]; other site
862962005276	structural Zn binding site [ion binding]; other site
862962005277	HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.2e-60
862962005278	PS00059 Zinc-containing alcohol dehydrogenases signature.
862962005279	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
862962005280	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
862962005281	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 4.3e-28
862962005282	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962005283	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962005284	catalytic residues [active]
862962005285	HMMPfam hit to PF00085, Thioredoxin, score 1.1e-18
862962005286	PS00194 Thioredoxin family active site.
862962005287	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962005288	Sulfatase; Region: Sulfatase; pfam00884
862962005289	HMMPfam hit to PF00884, Sulfatase, score 1.4e-29
862962005290	PS00523 Sulfatases signature 1.
862962005291	Signal peptide predicted for BF638R1295 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 24 and 25
862962005292	Protein P3 of Potyviral polyprotein; Region: Potyvirid-P3; pfam13608
862962005293	PAS fold; Region: PAS_3; pfam08447
862962005294	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962005295	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962005296	dimer interface [polypeptide binding]; other site
862962005297	phosphorylation site [posttranslational modification]
862962005298	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962005299	ATP binding site [chemical binding]; other site
862962005300	Mg2+ binding site [ion binding]; other site
862962005301	G-X-G motif; other site
862962005302	2 probable transmembrane helices predicted for BF638R1296 by TMHMM2.0 at aa 10-27 and 389-408
862962005303	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.2e-21
862962005304	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.5e-33
862962005305	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005306	9 probable transmembrane helices predicted for BF638R1297 by TMHMM2.0 at aa 7-26, 36-54, 93-115, 125-142, 155-177, 223-245, 257-279, 283-305 and 318-340
862962005307	Predicted membrane protein [Function unknown]; Region: COG2855
862962005308	HMMPfam hit to PF03601, Conserved hypothetical protein, score 1.3e-111
862962005309	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005310	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962005311	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
862962005312	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
862962005313	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
862962005314	6 probable transmembrane helices predicted for BF638R1298 by TMHMM2.0 at aa 27-46, 56-73, 258-280, 295-317, 596-615 and 619-641
862962005315	HMMPfam hit to PF00122, E1-E2 ATPase, score 1.1e-64
862962005316	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 6.9e-28
862962005317	PS00154 E1-E2 ATPases phosphorylation site.
862962005318	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
862962005319	metal binding site 2 [ion binding]; metal-binding site
862962005320	putative DNA binding helix; other site
862962005321	metal binding site 1 [ion binding]; metal-binding site
862962005322	dimer interface [polypeptide binding]; other site
862962005323	structural Zn2+ binding site [ion binding]; other site
862962005324	PS00190 Cytochrome c family heme-binding site signature.
862962005325	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962005326	Homeobox associated leucine zipper; Region: HALZ; pfam02183
862962005327	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962005328	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962005329	ligand binding site [chemical binding]; other site
862962005330	HMMPfam hit to PF00691, OmpA family, score 7.7e-11
862962005331	Signal peptide predicted for BF638R1300 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 31 and 32
862962005332	Uncharacterized conserved protein [Function unknown]; Region: COG3189
862962005333	HMMPfam hit to PF04343, Protein of unknown function, DUF488, score 1e-46
862962005334	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
862962005335	amidophosphoribosyltransferase; Region: purF; TIGR01134
862962005336	active site
862962005337	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962005338	active site
862962005339	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 0.00011
862962005340	peptidase T; Region: peptidase-T; TIGR01882
862962005341	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
862962005342	metal binding site [ion binding]; metal-binding site
862962005343	dimer interface [polypeptide binding]; other site
862962005344	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
862962005345	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
862962005346	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2.7e-29
862962005347	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
862962005348	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
862962005349	HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl tran, score 7e-108
862962005350	Signal peptide predicted for BF638R1306 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.741 between residues 21 and 22
862962005351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005352	5 probable transmembrane helices predicted for BF638R1306 by TMHMM2.0 at aa 217-239, 259-281, 301-323, 391-413 and 445-467
862962005353	membrane glycoprotein; Provisional; Region: PHA03332
862962005354	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005355	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
862962005356	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
862962005357	TrkA-C domain; Region: TrkA_C; pfam02080
862962005358	TrkA-C domain; Region: TrkA_C; pfam02080
862962005359	15 probable transmembrane helices predicted for BF638R1308 by TMHMM2.0 at aa 6-25, 32-51, 61-80, 87-109, 119-138, 151-173, 188-210, 222-244, 290-312, 332-354, 358-380, 419-441, 456-478, 499-521 and 526-548
862962005360	HMMPfam hit to PF02080, TrkA-C domain, score 7.1e-12
862962005361	HMMPfam hit to PF02080, TrkA-C domain, score 1e-09
862962005362	LysE type translocator; Region: LysE; cl00565
862962005363	6 probable transmembrane helices predicted for BF638R1309 by TMHMM2.0 at aa 10-32, 45-67, 77-96, 117-139, 154-176 and 189-211
862962005364	HMMPfam hit to PF01810, LysE type translocator, score 4.4e-09
862962005365	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
862962005366	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
862962005367	NADP binding site [chemical binding]; other site
862962005368	active site
862962005369	putative substrate binding site [chemical binding]; other site
862962005370	HMMPfam hit to PF04321, RmlD substrate binding domain, score 2.4e-64
862962005371	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
862962005372	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
862962005373	G1 box; other site
862962005374	putative GEF interaction site [polypeptide binding]; other site
862962005375	GTP/Mg2+ binding site [chemical binding]; other site
862962005376	Switch I region; other site
862962005377	G2 box; other site
862962005378	G3 box; other site
862962005379	Switch II region; other site
862962005380	G4 box; other site
862962005381	G5 box; other site
862962005382	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
862962005383	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 2.4e-64
862962005384	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005385	PS00301 GTP-binding elongation factors signature.
862962005386	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962005387	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
862962005388	active site
862962005389	motif I; other site
862962005390	motif II; other site
862962005391	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962005392	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
862962005393	CoenzymeA binding site [chemical binding]; other site
862962005394	subunit interaction site [polypeptide binding]; other site
862962005395	PHB binding site; other site
862962005396	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00075
862962005397	PS01228 Hypothetical cof family signature 1.
862962005398	HMMPfam hit to PF03061, Thioesterase superfamily, score 8.1e-16
862962005399	chorismate binding enzyme; Region: Chorismate_bind; cl10555
862962005400	HMMPfam hit to PF00425, chorismate binding enzyme, score 2.6e-14
862962005401	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
862962005402	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
862962005403	dimer interface [polypeptide binding]; other site
862962005404	tetramer interface [polypeptide binding]; other site
862962005405	PYR/PP interface [polypeptide binding]; other site
862962005406	TPP binding site [chemical binding]; other site
862962005407	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
862962005408	TPP-binding site; other site
862962005409	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.2e-06
862962005410	Signal peptide predicted for BF638R1317 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.472 between residues 27 and 28
862962005411	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
862962005412	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
862962005413	substrate binding site [chemical binding]; other site
862962005414	oxyanion hole (OAH) forming residues; other site
862962005415	trimer interface [polypeptide binding]; other site
862962005416	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.6e-68
862962005417	PS00166 Enoyl-CoA hydratase/isomerase signature.
862962005418	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
862962005419	O-succinylbenzoate synthase; Provisional; Region: PRK02714
862962005420	active site
862962005421	HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 0.00013
862962005422	PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2.
862962005423	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962005424	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
862962005425	AMP binding site [chemical binding]; other site
862962005426	active site
862962005427	acyl-activating enzyme (AAE) consensus motif; other site
862962005428	CoA binding site [chemical binding]; other site
862962005429	2 probable transmembrane helices predicted for BF638R1321 by TMHMM2.0 at aa 10-32 and 44-66
862962005430	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
862962005431	putative catalytic site [active]
862962005432	putative metal binding site [ion binding]; other site
862962005433	putative phosphate binding site [ion binding]; other site
862962005434	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005435	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3.1e-13
862962005436	2 probable transmembrane helices predicted for BF638R1322 by TMHMM2.0 at aa 4-26 and 39-56
862962005437	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
862962005438	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005439	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962005440	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962005441	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962005442	DNA binding residues [nucleotide binding]
862962005443	HMMPfam hit to PF04542, Sigma-70 region, score 0.0025
862962005444	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962005445	FecR protein; Region: FecR; pfam04773
862962005446	1 probable transmembrane helix predicted for BF638R1324 by TMHMM2.0 at aa 101-123
862962005447	HMMPfam hit to PF04773, FecR protein, score 9.7e-30
862962005448	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962005449	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962005450	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962005451	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962005452	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962005453	Signal peptide predicted for BF638R1325 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.760 between residues 27 and 28
862962005454	1 probable transmembrane helix predicted for BF638R1325 by TMHMM2.0 at aa 9-28
862962005455	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 9.2e-07
862962005456	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.7e-16
862962005457	HMMPfam hit to PF00593, TonB dependent receptor, score 2.3e-13
862962005458	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
862962005459	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962005460	Signal peptide predicted for BF638R1326 by SignalP 2.0 HMM (Signal peptide probability 0.718) with cleavage site probability 0.314 between residues 22 and 23
862962005461	Endo-beta-N-acetylglucosaminidases are bacterial chitinases that hydrolyze the chitin core of various asparagine (N)-linked glycans and glycoproteins. The endo-beta-N-acetylglucosaminidases have a glycosyl hydrolase family 18 (GH18) catalytic domain; Region: GH18_EndoS-like; cd06542
862962005462	active site
862962005463	Signal peptide predicted for BF638R1327 by SignalP 2.0 HMM (Signal peptide probability 0.952) with cleavage site probability 0.538 between residues 25 and 26
862962005464	1 probable transmembrane helix predicted for BF638R1327 by TMHMM2.0 at aa 54-76
862962005465	PS01095 Chitinases family 18 active site.
862962005466	Signal peptide predicted for BF638R1328 by SignalP 2.0 HMM (Signal peptide probability 0.938) with cleavage site probability 0.450 between residues 33 and 34
862962005467	Signal peptide predicted for BF638R1329 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.436 between residues 28 and 29
862962005468	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
862962005469	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
862962005470	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005471	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
862962005472	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
862962005473	Signal peptide predicted for BF638R1330 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.598 between residues 24 and 25
862962005474	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005475	HMMPfam hit to PF00754, F5/8 type C domain, score 0.0012
862962005476	muropeptide transporter; Reviewed; Region: ampG; PRK11902
862962005477	muropeptide transporter; Validated; Region: ampG; cl17669
862962005478	Signal peptide predicted for BF638R1331 by SignalP 2.0 HMM (Signal peptide probability 0.737) with cleavage site probability 0.271 between residues 27 and 28
862962005479	12 probable transmembrane helices predicted for BF638R1331 by TMHMM2.0 at aa 12-34, 44-66, 73-95, 99-116, 137-159, 169-191, 229-251, 271-293, 300-322, 327-349, 362-384 and 394-416
862962005480	Domain of unknown function (DUF377); Region: DUF377; pfam04041
862962005481	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
862962005482	active site
862962005483	HMMPfam hit to PF04041, Domain of unknown function (DUF377), score 7.1e-94
862962005484	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005485	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962005486	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
862962005487	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
862962005488	dimerization interface [polypeptide binding]; other site
862962005489	DPS ferroxidase diiron center [ion binding]; other site
862962005490	ion pore; other site
862962005491	HMMPfam hit to PF00210, Ferritin-like domain, score 7.9e-23
862962005492	PS00819 Dps protein family signature 2.
862962005493	PS00818 Dps protein family signature 1.
862962005494	Transcriptional regulator [Transcription]; Region: LysR; COG0583
862962005495	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
862962005496	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
862962005497	dimerization interface [polypeptide binding]; other site
862962005498	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-14
862962005499	PS00044 Bacterial regulatory proteins, lysR family signature.
862962005500	HMMPfam hit to PF03466, LysR substrate binding domain, score 1e-49
862962005501	NigD-like protein; Region: NigD; pfam12667
862962005502	Signal peptide predicted for BF638R1335 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.389 between residues 23 and 24
862962005503	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005504	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962005505	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962005506	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962005507	DNA binding residues [nucleotide binding]
862962005508	HMMPfam hit to PF04542, Sigma-70 region, score 2.4e-14
862962005509	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962005510	1 probable transmembrane helix predicted for BF638R1337 by TMHMM2.0 at aa 49-71
862962005511	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
862962005512	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962005513	FeS/SAM binding site; other site
862962005514	Uncharacterized protein conserved in archaea (DUF2119); Region: DUF2119; cl01685
862962005515	HMMPfam hit to PF04055, Radical SAM superfamily, score 6e-28
862962005516	PS01087 Radical activating enzymes signature.
862962005517	Pyruvate formate lyase 1; Region: PFL1; cd01678
862962005518	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
862962005519	coenzyme A binding site [chemical binding]; other site
862962005520	active site
862962005521	catalytic residues [active]
862962005522	glycine loop; other site
862962005523	HMMPfam hit to PF01228, Glycine radical, score 1.5e-53
862962005524	PS00850 Glycine radical signature.
862962005525	HMMPfam hit to PF02901, Pyruvate formate lyase, score 8.7e-271
862962005526	1 probable transmembrane helix predicted for BF638R1340 by TMHMM2.0 at aa 12-31
862962005527	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962005528	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962005529	Int/Topo IB signature motif; other site
862962005530	HMMPfam hit to PF00589, Phage integrase family, score 9.6e-11
862962005531	Restriction endonuclease; Region: Mrr_cat; pfam04471
862962005532	putative conjugative transposon
862962005533	Antirestriction protein (ArdA); Region: ArdA; pfam07275
862962005534	HMMPfam hit to PF07275, Antirestriction protein (ArdA), score 4.3e-73
862962005535	PS00019 Actinin-type actin-binding domain signature 1.
862962005536	Domain of unknown function, B. Theta Gene description (DUF3873); Region: DUF3873; pfam12989
862962005537	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
862962005538	Part of AAA domain; Region: AAA_19; pfam13245
862962005539	Family description; Region: UvrD_C_2; pfam13538
862962005540	HMMPfam hit to PF00580, UvrD/REP helicase, score 8.5e-13
862962005541	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962005543	AAA domain; Region: AAA_21; pfam13304
862962005544	Walker A/P-loop; other site
862962005545	ATP binding site [chemical binding]; other site
862962005546	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
862962005547	putative active site [active]
862962005548	putative metal-binding site [ion binding]; other site
862962005549	PS00359 Ribosomal protein L11 signature.
862962005550	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005551	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
862962005552	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005553	Signal peptide predicted for BF638R1351 by SignalP 2.0 HMM (Signal peptide probability 0.753) with cleavage site probability 0.627 between residues 25 and 26
862962005554	Signal peptide predicted for BF638R1350 by SignalP 2.0 HMM (Signal peptide probability 0.838) with cleavage site probability 0.695 between residues 23 and 24
862962005555	Conjugative transposon protein TraO; Region: TraO; pfam10626
862962005556	Signal peptide predicted for BF638R1352 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23
862962005557	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
862962005558	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
862962005559	Signal peptide predicted for BF638R1353 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.537 between residues 23 and 24
862962005560	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
862962005561	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
862962005562	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962005563	1 probable transmembrane helix predicted for BF638R1354 by TMHMM2.0 at aa 41-60
862962005564	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005565	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
862962005566	1 probable transmembrane helix predicted for BF638R1355 by TMHMM2.0 at aa 32-54
862962005567	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
862962005568	Signal peptide predicted for BF638R1356 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.886 between residues 42 and 43
862962005569	1 probable transmembrane helix predicted for BF638R1356 by TMHMM2.0 at aa 15-37
862962005570	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
862962005571	HMMPfam hit to PF07863, Homologues of TraJ from Bacteroides conju, score 5.3e-18
862962005572	5 probable transmembrane helices predicted for BF638R1357 by TMHMM2.0 at aa 25-47, 68-90, 194-216, 223-245 and 273-295; 5 probable transmembrane helices predicted for BF638R1358 by TMHMM2.0 at aa 27-49, 70-92, 196-218, 225-247 and 275-297
862962005573	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
862962005574	Signal peptide predicted for BF638R1359 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 20 and 21
862962005575	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962005576	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005577	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
862962005578	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962005579	putative active site [active]
862962005580	putative NTP binding site [chemical binding]; other site
862962005581	putative nucleic acid binding site [nucleotide binding]; other site
862962005582	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962005583	Type II intron maturase; Region: Intron_maturas2; pfam01348
862962005584	PS00190 Cytochrome c family heme-binding site signature.
862962005585	HMMPfam hit to PF01348, Type II intron maturase, score 1.5e-08
862962005586	HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent, score 4.1e-80
862962005587	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
862962005588	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
862962005589	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005590	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005591	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
862962005592	2 probable transmembrane helices predicted for BF638R1364 by TMHMM2.0 at aa 23-45 and 49-71
862962005593	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
862962005594	3 probable transmembrane helices predicted for BF638R1365 by TMHMM2.0 at aa 5-22, 45-62 and 75-97
862962005595	Signal peptide predicted for BF638R1365 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.676 between residues 20 and 21
862962005596	1 probable transmembrane helix predicted for BF638R1366 by TMHMM2.0 at aa 2-21
862962005597	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962005598	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
862962005599	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962005600	P-loop; other site
862962005601	Magnesium ion binding site [ion binding]; other site
862962005602	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
862962005603	YWFCY protein; Region: YWFCY; pfam14293
862962005604	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
862962005605	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
862962005606	5 probable transmembrane helices predicted for BF638R1373 by TMHMM2.0 at aa 20-42, 57-79, 91-113, 123-145 and 313-332
862962005607	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005608	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005609	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
862962005610	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
862962005611	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
862962005612	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
862962005613	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005614	DNA topoisomerase III; Provisional; Region: PRK07726
862962005615	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
862962005616	active site
862962005617	putative interdomain interaction site [polypeptide binding]; other site
862962005618	putative metal-binding site [ion binding]; other site
862962005619	putative nucleotide binding site [chemical binding]; other site
862962005620	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962005621	domain I; other site
862962005622	DNA binding groove [nucleotide binding]
862962005623	phosphate binding site [ion binding]; other site
862962005624	domain II; other site
862962005625	domain III; other site
862962005626	nucleotide binding site [chemical binding]; other site
862962005627	catalytic site [active]
862962005628	domain IV; other site
862962005629	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
862962005630	HMMPfam hit to PF01751, Toprim domain, score 1.8e-17
862962005631	HMMPfam hit to PF01131, DNA topoisomerase, score 4.2e-92
862962005632	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
862962005633	RibD C-terminal domain; Region: RibD_C; cl17279
862962005634	HMMPfam hit to PF01872, RibD C-terminal domain, score 9.1e-08
862962005635	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
862962005636	active site
862962005637	metal binding site [ion binding]; metal-binding site
862962005638	interdomain interaction site; other site
862962005639	AAA domain; Region: AAA_25; pfam13481
862962005640	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
862962005641	Walker A motif; other site
862962005642	ATP binding site [chemical binding]; other site
862962005643	Walker B motif; other site
862962005644	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005645	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005646	Helix-turn-helix domain; Region: HTH_17; cl17695
862962005647	RteC protein; Region: RteC; pfam09357
862962005648	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962005649	3 probable transmembrane helices predicted for BF638R1384 by TMHMM2.0 at aa 55-77, 81-103 and 124-146
862962005650	1 probable transmembrane helix predicted for BF638R1385 by TMHMM2.0 at aa 41-63
862962005651	Domain of unknown function (DUF1910); Region: DUF1910; pfam08928
862962005652	Domain of unknown function (DUF1911); Region: DUF1911; pfam08929
862962005653	4 probable transmembrane helices predicted for BF638R1389 by TMHMM2.0 at aa 7-29, 39-57, 64-86 and 115-137
862962005654	Domain of unknown function (DUF1910); Region: DUF1910; pfam08928
862962005655	Domain of unknown function (DUF1911); Region: DUF1911; pfam08929
862962005656	3 probable transmembrane helices predicted for BF638R1392 by TMHMM2.0 at aa 78-100, 110-129 and 150-172
862962005657	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005658	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
862962005659	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
862962005660	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962005661	active site
862962005662	DNA binding site [nucleotide binding]
862962005663	Int/Topo IB signature motif; other site
862962005664	HMMPfam hit to PF00589, Phage integrase family, score 1e-31
862962005665	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 0.00052
862962005666	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962005667	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962005668	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
862962005669	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.9e-05
862962005670	1 probable transmembrane helix predicted for BF638R1395 by TMHMM2.0 at aa 5-22
862962005671	2 probable transmembrane helices predicted for BF638R1397 by TMHMM2.0 at aa 100-122 and 142-164
862962005672	MG2 domain; Region: A2M_N; pfam01835
862962005673	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
862962005674	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
862962005675	Signal peptide predicted for BF638R1398 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.774 between residues 22 and 23
862962005676	1 probable transmembrane helix predicted for BF638R1400 by TMHMM2.0 at aa 7-29
862962005677	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
862962005678	KIAA1161 is an uncharacterized Homo sapiens protein with a glycosyl hydrolase family 31 (GH31) domain that is homologous to the Escherichia coli YihQ glucosidase. Orthologs of KIA1161 are found in eukaryotes and prokaryotes. In bacteria, YihQ (along with...; Region: GH31_glucosidase_KIAA1161; cd06592
862962005679	putative active site [active]
862962005680	putative catalytic site [active]
862962005681	Signal peptide predicted for BF638R1401 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.971 between residues 43 and 44
862962005682	2 probable transmembrane helices predicted for BF638R1401 by TMHMM2.0 at aa 5-22 and 27-44
862962005683	HMMPfam hit to PF01055, Glycosyl hydrolases family, score 6.6e-43
862962005684	Signal peptide predicted for BF638R1402 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.427 between residues 24 and 25
862962005685	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005686	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
862962005687	Domain of unknown function DUF21; Region: DUF21; pfam01595
862962005688	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
862962005689	Transporter associated domain; Region: CorC_HlyC; smart01091
862962005690	HMMPfam hit to PF03471, Transporter associated domain, score 1.2e-16
862962005691	HMMPfam hit to PF00571, CBS domain, score 5.3e-06
862962005692	HMMPfam hit to PF00571, CBS domain, score 6e-08
862962005693	HMMPfam hit to PF01595, Domain of unknown function DUF21, score 5.7e-73
862962005694	4 probable transmembrane helices predicted for BF638R1403 by TMHMM2.0 at aa 4-26, 56-78, 98-120 and 133-155
862962005695	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
862962005696	HMMPfam hit to PF01435, Peptidase family M48, score 2.3e-15
862962005697	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962005698	1 probable transmembrane helix predicted for BF638R1404 by TMHMM2.0 at aa 5-24
862962005699	Signal peptide predicted for BF638R1404 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.743 between residues 22 and 23
862962005700	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962005701	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962005702	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962005703	HMMPfam hit to PF00593, TonB dependent receptor, score 1.7e-18
862962005704	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-12
862962005705	1 probable transmembrane helix predicted for BF638R1405 by TMHMM2.0 at aa 17-34
862962005706	Signal peptide predicted for BF638R1405 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 31 and 32
862962005707	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
862962005708	Predicted esterase [General function prediction only]; Region: COG0627
862962005709	S-formylglutathione hydrolase; Region: PLN02442
862962005710	Signal peptide predicted for BF638R1407 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.491 between residues 20 and 21
862962005711	1 probable transmembrane helix predicted for BF638R1407 by TMHMM2.0 at aa 5-23
862962005712	HMMPfam hit to PF00756, Putative esterase, score 1.6e-18
862962005713	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
862962005714	Signal peptide predicted for BF638R1408 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.553 between residues 21 and 22
862962005715	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005716	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
862962005717	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
862962005718	homodimer interface [polypeptide binding]; other site
862962005719	substrate-cofactor binding pocket; other site
862962005720	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962005721	catalytic residue [active]
862962005722	HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 2.2e-208
862962005723	PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site.
862962005724	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
862962005725	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
862962005726	HMMPfam hit to PF03054, tRNA methyl transferase, score 1.4e-124
862962005727	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962005728	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
862962005729	DNA binding residues [nucleotide binding]
862962005730	dimerization interface [polypeptide binding]; other site
862962005731	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 4.2e-16
862962005732	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
862962005733	1 probable transmembrane helix predicted for BF638R1413 by TMHMM2.0 at aa 4-21
862962005734	Signal peptide predicted for BF638R1413 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.646 between residues 19 and 20
862962005735	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
862962005736	HMMPfam hit to PF03553, Na+/H+ antiporter family, score 4.1e-49
862962005737	10 probable transmembrane helices predicted for BF638R1414 by TMHMM2.0 at aa 7-29, 39-60, 73-95, 105-127, 194-216, 231-253, 260-277, 334-356, 368-390 and 447-469
862962005738	Signal peptide predicted for BF638R1414 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.270 between residues 29 and 30
862962005739	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
862962005740	diiron binding motif [ion binding]; other site
862962005741	CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431
862962005742	4 probable transmembrane helices predicted for BF638R1415 by TMHMM2.0 at aa 202-224, 237-259, 264-286 and 303-325
862962005743	HMMPfam hit to PF01988, Integral membrane protein DUF125, score 4.2e-38
862962005744	4 probable transmembrane helices predicted for BF638R1416 by TMHMM2.0 at aa 9-31, 37-59, 80-102 and 112-134
862962005745	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
862962005746	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962005747	putative substrate translocation pore; other site
862962005748	12 probable transmembrane helices predicted for BF638R1417 by TMHMM2.0 at aa 9-31, 51-73, 80-99, 104-126, 139-161, 171-188, 218-237, 252-274, 281-300, 305-327, 340-362 and 366-388
862962005749	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.4e-44
862962005750	Signal peptide predicted for BF638R1417 by SignalP 2.0 HMM (Signal peptide probability 0.755) with cleavage site probability 0.638 between residues 28 and 29
862962005751	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
862962005752	Transglycosylase; Region: Transgly; pfam00912
862962005753	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
862962005754	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
862962005755	HMMPfam hit to PF06832, Penicillin-Binding Protein C-terminus, score 2.1e-28
862962005756	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 5.4e-06
862962005757	HMMPfam hit to PF00912, Transglycosylase, score 5.1e-54
862962005758	Signal peptide predicted for BF638R1418 by SignalP 2.0 HMM (Signal peptide probability 0.959) with cleavage site probability 0.737 between residues 48 and 49
862962005759	MG2 domain; Region: A2M_N; pfam01835
862962005760	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
862962005761	Alpha-2-macroglobulin family; Region: A2M; pfam00207
862962005762	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
862962005763	surface patch; other site
862962005764	thioester region; other site
862962005765	specificity defining residues; other site
862962005766	HMMPfam hit to PF07703, Alpha-2-macroglobulin family N-terminal regi, score 1.3e-17
862962005767	HMMPfam hit to PF01835, Alpha-2-macroglobulin family N-terminal regi, score 1.5e-62
862962005768	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005769	Signal peptide predicted for BF638R1419 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.566 between residues 24 and 25
862962005770	1 probable transmembrane helix predicted for BF638R1419 by TMHMM2.0 at aa 7-24
862962005771	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
862962005772	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
862962005773	Ligand Binding Site [chemical binding]; other site
862962005774	TilS substrate C-terminal domain; Region: TilS_C; smart00977
862962005775	HMMPfam hit to PF01171, PP-loop family, score 1.1e-74
862962005776	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962005777	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
862962005778	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
862962005779	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
862962005780	G1 box; other site
862962005781	GTP/Mg2+ binding site [chemical binding]; other site
862962005782	Switch I region; other site
862962005783	G2 box; other site
862962005784	G3 box; other site
862962005785	Switch II region; other site
862962005786	G4 box; other site
862962005787	G5 box; other site
862962005788	Nucleoside recognition; Region: Gate; pfam07670
862962005789	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
862962005790	Nucleoside recognition; Region: Gate; pfam07670
862962005791	HMMPfam hit to PF04023, FeoA domain, score 1.2e-23
862962005792	HMMPfam hit to PF01926, GTPase of unknown function, score 1.5e-33
862962005793	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005794	HMMPfam hit to PF02421, Ferrous iron transport protein B, score 7.4e-49
862962005795	8 probable transmembrane helices predicted for BF638R1421 by TMHMM2.0 at aa 443-465, 500-522, 545-567, 582-604, 609-631, 672-689, 769-791 and 801-823
862962005796	HMMPfam hit to PF07670, Nucleoside recognition, score 2e-17
862962005797	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005798	HMMPfam hit to PF07664, Ferrous iron transport protein B C terminus, score 7e-24
862962005799	HMMPfam hit to PF07670, Nucleoside recognition, score 1.1e-21
862962005800	1 probable transmembrane helix predicted for BF638R1422 by TMHMM2.0 at aa 5-27
862962005801	Transposase; Region: DDE_Tnp_ISL3; pfam01610
862962005802	Fic family protein [Function unknown]; Region: COG3177
862962005803	Fic/DOC family; Region: Fic; pfam02661
862962005804	HMMPfam hit to PF02661, Fic protein family, score 5.8e-08
862962005805	Signal peptide predicted for BF638R1428 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 19 and 20
862962005806	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005807	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962005808	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
862962005809	Signal peptide predicted for BF638R1430 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.348 between residues 32 and 33
862962005810	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005811	Signal peptide predicted for BF638R1431 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.694 between residues 31 and 32
862962005812	similar to PS_2/PS_A lipopolysaccharide biosynthesis locus in BF9343
862962005813	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962005814	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962005815	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 3.2e-78
862962005816	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962005817	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962005818	active site
862962005819	homodimer interface [polypeptide binding]; other site
862962005820	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1.2e-147
862962005821	WxcM-like, C-terminal; Region: FdtA; pfam05523
862962005822	WxcM-like, C-terminal; Region: FdtA; pfam05523
862962005823	HMMPfam hit to PF05523, WxcM-like, C-terminal, score 1.6e-61
862962005824	HMMPfam hit to PF05523, WxcM-like, C-terminal, score 1.6e-72
862962005825	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
862962005826	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
862962005827	putative trimer interface [polypeptide binding]; other site
862962005828	putative active site [active]
862962005829	putative substrate binding site [chemical binding]; other site
862962005830	putative CoA binding site [chemical binding]; other site
862962005831	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 49
862962005832	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.15
862962005833	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.038
862962005834	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 4.6
862962005835	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.42
862962005836	PS00101 Hexapeptide-repeat containing-transferases signature.
862962005837	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 38
862962005838	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
862962005839	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962005840	inhibitor-cofactor binding pocket; inhibition site
862962005841	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962005842	catalytic residue [active]
862962005843	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 5.4e-109
862962005844	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962005845	12 probable transmembrane helices predicted for BF638R1439 by TMHMM2.0 at aa 20-39, 49-71, 99-121, 131-150, 163-185, 191-213, 320-342, 352-374, 381-403, 407-429, 445-467 and 471-493
862962005846	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005847	12 probable transmembrane helices predicted for BF638R1440 by TMHMM2.0 at aa 17-39, 60-78, 93-115, 128-150, 155-177, 190-211, 221-238, 245-262, 266-283, 300-322, 412-434 and 447-469
862962005848	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962005849	Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605
862962005850	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
862962005851	HMMPfam hit to PF00288, GHMP kinases putative ATP-binding protei, score 4.3e-24
862962005852	PS00107 Protein kinases ATP-binding region signature.
862962005853	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962005854	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
862962005855	NAD(P) binding site [chemical binding]; other site
862962005856	active site
862962005857	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
862962005858	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962005859	active site
862962005860	motif I; other site
862962005861	motif II; other site
862962005862	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
862962005863	dimer interface [polypeptide binding]; other site
862962005864	active site
862962005865	HMMPfam hit to PF01380, SIS domain, score 1.7e-06
862962005866	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962005867	WcbM_like is a subfamily of nucleotidyl transferases; Region: NTP_transferase_WcbM_like; cd06915
862962005868	Substrate binding site; other site
862962005869	Mg++ binding site; other site
862962005870	metal-binding site
862962005871	Mg++ binding site; other site
862962005872	metal-binding site
862962005873	HMMPfam hit to PF00483, Nucleotidyl transferase, score 3.5e-12
862962005874	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962005875	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962005876	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962005877	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005878	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.8e-05
862962005880	Cupin domain; Region: Cupin_2; cl17218
862962005881	HMMPfam hit to PF07883, Cupin domain, score 3.1e-06
862962005882	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
862962005883	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962005884	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005885	HMMPfam hit to PF00534, Glycosyl transferases group, score 1e-06
862962005886	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962005887	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962005888	substrate binding site; other site
862962005889	tetramer interface; other site
862962005890	HMMPfam hit to PF00483, Nucleotidyl transferase, score 3.3e-107
862962005891	1 probable transmembrane helix predicted for BF638R1455 by TMHMM2.0 at aa 85-102
862962005892	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
862962005893	classical (c) SDRs; Region: SDR_c; cd05233
862962005894	NAD(P) binding site [chemical binding]; other site
862962005895	active site
862962005896	HMMPfam hit to PF00106, short chain dehydrogenase, score 3.7e-55
862962005897	1 probable transmembrane helix predicted for BF638R1457 by TMHMM2.0 at aa 138-160
862962005898	PS00061 Short-chain dehydrogenases/reductases family signature.
862962005899	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005900	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
862962005901	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
862962005902	dimer interface [polypeptide binding]; other site
862962005903	active site
862962005904	CoA binding pocket [chemical binding]; other site
862962005905	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005906	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
862962005907	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962005908	inhibitor-cofactor binding pocket; inhibition site
862962005909	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962005910	catalytic residue [active]
862962005911	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.2e-85
862962005912	Bacterial sugar transferase; Region: Bac_transf; pfam02397
862962005913	HMMPfam hit to PF02397, Bacterial sugar transferase, score 1.2e-25
862962005914	1 probable transmembrane helix predicted for BF638R1460 by TMHMM2.0 at aa 7-29
862962005915	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962005916	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962005917	catalytic residues [active]
862962005918	Signal peptide predicted for BF638R1461 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.382 between residues 27 and 28
862962005919	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005920	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
862962005921	transmembrane helices; other site
862962005922	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
862962005923	TrkA-C domain; Region: TrkA_C; pfam02080
862962005924	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
862962005925	TrkA-C domain; Region: TrkA_C; pfam02080
862962005926	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
862962005927	Signal peptide predicted for BF638R1462 by SignalP 2.0 HMM (Signal peptide probability 0.938) with cleavage site probability 0.881 between residues 22 and 23
862962005928	11 probable transmembrane helices predicted for BF638R1462 by TMHMM2.0 at aa 24-41, 51-72, 93-115, 135-157, 169-191, 440-462, 475-494, 504-526, 533-552, 562-584 and 597-619
862962005929	HMMPfam hit to PF02080, TrkA-C domain, score 7.4e-13
862962005930	HMMPfam hit to PF02080, TrkA-C domain, score 1.8e-07
862962005931	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005932	Methyltransferase domain; Region: Methyltransf_31; pfam13847
862962005933	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962005934	S-adenosylmethionine binding site [chemical binding]; other site
862962005935	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962005936	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
862962005937	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
862962005938	dimer interface [polypeptide binding]; other site
862962005939	active site
862962005940	metal binding site [ion binding]; metal-binding site
862962005941	glutathione binding site [chemical binding]; other site
862962005942	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 8.2e-10
862962005943	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
862962005944	Signal peptide predicted for BF638R1466 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.998 between residues 22 and 23
862962005945	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
862962005946	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
862962005947	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
862962005948	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
862962005949	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
862962005950	PS01064 Pyridoxamine 5'-phosphate oxidase signature.
862962005951	HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 1.6e-27
862962005952	Pirin-related protein [General function prediction only]; Region: COG1741
862962005953	Pirin; Region: Pirin; pfam02678
862962005954	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005955	HMMPfam hit to PF02678, Pirin, score 4.9e-45
862962005956	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962005957	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962005958	Signal peptide predicted for BF638R1470 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.799 between residues 24 and 25
862962005959	2 probable transmembrane helices predicted for BF638R1470 by TMHMM2.0 at aa 7-29 and 385-404
862962005960	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.2
862962005961	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.015; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0035
862962005962	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.35; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.6
862962005963	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.88; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.18
862962005964	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.5
862962005965	PS00041 Bacterial regulatory proteins, araC family signature.
862962005966	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.3e-08
862962005967	Chagasin family peptidase inhibitor I42; Region: Inhibitor_I42; pfam09394
862962005968	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
862962005969	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
862962005970	putative ligand binding site [chemical binding]; other site
862962005971	putative NAD binding site [chemical binding]; other site
862962005972	catalytic site [active]
862962005973	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 2.3e-84
862962005974	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
862962005975	PS00017 ATP/GTP-binding site motif A (P-loop).
862962005976	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 3.8e-19
862962005977	Signal peptide predicted for BF638R1474 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.981 between residues 20 and 21
862962005978	1 probable transmembrane helix predicted for BF638R1474 by TMHMM2.0 at aa 5-27
862962005979	HMMPfam hit to PF03349, Outer membrane protein transport protein (O, score 0.00025
862962005980	Signal peptide predicted for BF638R1475 by SignalP 2.0 HMM (Signal peptide probability 0.704) with cleavage site probability 0.360 between residues 38 and 39
862962005981	Signal peptide predicted for BF638R1476 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 23 and 24
862962005982	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962005983	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962005984	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962005985	DNA binding residues [nucleotide binding]
862962005986	HMMPfam hit to PF04542, Sigma-70 region, score 4.5e-13
862962005987	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
862962005988	Signal peptide predicted for BF638R1478 by SignalP 2.0 HMM (Signal peptide probability 0.811) with cleavage site probability 0.731 between residues 22 and 23
862962005989	6 probable transmembrane helices predicted for BF638R1478 by TMHMM2.0 at aa 7-26, 30-52, 65-87, 107-129, 149-171 and 175-197
862962005990	HMMPfam hit to PF02592, Uncharacterized ACR, YhhQ family COG1738, score 3.2e-26
862962005991	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
862962005992	Ligand Binding Site [chemical binding]; other site
862962005993	HMMPfam hit to PF06508, ExsB, score 2.2e-37
862962005994	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
862962005995	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 6e-50
862962005996	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
862962005997	HMMPfam hit to PF02590, Uncharacterized ACR, COG1576, score 1.3e-58
862962005998	2 probable transmembrane helices predicted for BF638R1483 by TMHMM2.0 at aa 30-47 and 57-79
862962005999	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
862962006000	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
862962006001	dimerization interface [polypeptide binding]; other site
862962006002	active site
862962006003	HMMPfam hit to PF02749, Quinolinate phosphoribosyl transferase, N-t, score 1.7e-29
862962006004	HMMPfam hit to PF01729, Quinolinate phosphoribosyl transferase, C-t, score 3.8e-87
862962006005	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962006006	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962006007	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962006008	DNA binding residues [nucleotide binding]
862962006009	HMMPfam hit to PF04542, Sigma-70 region, score 5.6e-14
862962006010	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962006011	1 probable transmembrane helix predicted for BF638R1486 by TMHMM2.0 at aa 45-67
862962006012	Signal peptide predicted for BF638R1487 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.509 between residues 23 and 24
862962006013	Signal peptide predicted for BF638R1488 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 19 and 20
862962006014	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
862962006015	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
862962006016	FMN binding site [chemical binding]; other site
862962006017	substrate binding site [chemical binding]; other site
862962006018	putative catalytic residue [active]
862962006019	HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 2e-78
862962006020	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
862962006021	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
862962006022	hexamer interface [polypeptide binding]; other site
862962006023	ligand binding site [chemical binding]; other site
862962006024	putative active site [active]
862962006025	NAD(P) binding site [chemical binding]; other site
862962006026	HMMPfam hit to PF01262, Alanine dehydrogenase/PNT, C-terminal dom, score 1.9e-90
862962006027	HMMPfam hit to PF05222, Alanine dehydrogenase/PNT, N-terminal dom, score 1.3e-61
862962006028	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962006029	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
862962006030	Signal peptide predicted for BF638R1491 by SignalP 2.0 HMM (Signal peptide probability 0.946) with cleavage site probability 0.875 between residues 18 and 19
862962006031	HMMPfam hit to PF01551, Peptidase family M23, score 7.7e-10
862962006032	Peptidase family C69; Region: Peptidase_C69; cl17793
862962006033	Signal peptide predicted for BF638R1492 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.546 between residues 16 and 17
862962006034	HMMPfam hit to PF03577, Peptidase family U34, score 8e-179
862962006035	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
862962006036	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
862962006037	active site
862962006038	substrate binding site [chemical binding]; other site
862962006039	metal binding site [ion binding]; metal-binding site
862962006040	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 8e-58
862962006041	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
862962006042	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 0.00049
862962006043	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 0.013
862962006044	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962006045	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962006046	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962006047	DNA binding residues [nucleotide binding]
862962006048	HMMPfam hit to PF04542, Sigma-70 region, score 4.9e-07
862962006049	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962006050	FecR protein; Region: FecR; pfam04773
862962006051	HMMPfam hit to PF04773, FecR protein, score 3.1e-33
862962006052	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962006053	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962006054	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962006055	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962006056	Signal peptide predicted for BF638R1496 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.856 between residues 45 and 46
862962006057	1 probable transmembrane helix predicted for BF638R1496 by TMHMM2.0 at aa 21-43
862962006058	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 2.6e-07
862962006059	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.7e-17
862962006060	HMMPfam hit to PF00593, TonB dependent receptor, score 5.5e-17
862962006061	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962006062	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962006063	SusD family; Region: SusD; pfam07980
862962006064	Signal peptide predicted for BF638R1497 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.754 between residues 19 and 20
862962006065	1 probable transmembrane helix predicted for BF638R1497 by TMHMM2.0 at aa 7-24
862962006066	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006067	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962006068	Signal peptide predicted for BF638R1498 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.669 between residues 22 and 23
862962006069	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006070	He_PIG associated, NEW1 domain of bacterial glycohydrolase; Region: He_PIG_assoc; pfam10632
862962006071	Putative Ig domain; Region: He_PIG; pfam05345
862962006072	alpha-galactosidase; Region: PLN02808; cl17638
862962006073	Signal peptide predicted for BF638R1499 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 24 and 25
862962006074	1 probable transmembrane helix predicted for BF638R1499 by TMHMM2.0 at aa 7-29
862962006075	HMMPfam hit to PF05345, Putative Ig domain, score 3.5e-07
862962006076	HMMPfam hit to PF02065, Melibiase, score 3.6e-09
862962006077	Histidine carboxylase PI chain; Region: HDC; pfam02329
862962006078	HMMPfam hit to PF02329, Histidine carboxylase PI chain, score 1.3e-58
862962006079	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
862962006080	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
862962006081	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
862962006082	putative NADH binding site [chemical binding]; other site
862962006083	putative active site [active]
862962006084	nudix motif; other site
862962006085	putative metal binding site [ion binding]; other site
862962006086	HMMPfam hit to PF00293, NUDIX domain, score 5.2e-23
862962006087	PS00893 mutT domain signature.
862962006088	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
862962006089	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962006090	Walker A/P-loop; other site
862962006091	ATP binding site [chemical binding]; other site
862962006092	Q-loop/lid; other site
862962006093	ABC transporter signature motif; other site
862962006094	Walker B; other site
862962006095	D-loop; other site
862962006096	H-loop/switch region; other site
862962006097	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962006098	HMMPfam hit to PF00005, ABC transporter, score 1.3e-25
862962006099	PS00211 ABC transporters family signature.
862962006100	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006101	HMMPfam hit to PF00005, ABC transporter, score 2.6e-31
862962006102	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006103	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
862962006104	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
862962006105	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962006106	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
862962006107	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 2.8e-29
862962006108	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.1e-66
862962006109	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006110	Predicted membrane protein [Function unknown]; Region: COG3059
862962006111	HMMPfam hit to PF04224, Protein of unknown function, DUF417, score 2.9e-79
862962006112	4 probable transmembrane helices predicted for BF638R1504 by TMHMM2.0 at aa 20-42, 52-74, 104-126 and 131-150
862962006113	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962006114	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962006115	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.6e-07
862962006116	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
862962006117	active site
862962006118	catalytic motif [active]
862962006119	Zn binding site [ion binding]; other site
862962006120	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase, score 1.2e-11
862962006121	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
862962006122	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
862962006123	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962006124	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962006125	Signal peptide predicted for BF638R1507 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.775 between residues 23 and 24
862962006126	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 1.9e-39
862962006127	HMMPfam hit to PF01476, LysM domain, score 1.2e-05
862962006128	HMMPfam hit to PF01476, LysM domain, score 3.5e-07
862962006129	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962006130	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962006131	1 probable transmembrane helix predicted for BF638R1509 by TMHMM2.0 at aa 21-43
862962006132	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006133	FtsX-like permease family; Region: FtsX; pfam02687
862962006134	4 probable transmembrane helices predicted for BF638R1510 by TMHMM2.0 at aa 26-48, 300-322, 350-372 and 387-409
862962006135	HMMPfam hit to PF02687, Predicted permease, score 4.4e-18
862962006136	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006137	FtsX-like permease family; Region: FtsX; pfam02687
862962006138	4 probable transmembrane helices predicted for BF638R1511 by TMHMM2.0 at aa 21-43, 298-320, 341-363 and 383-405
862962006139	HMMPfam hit to PF02687, Predicted permease, score 0.00018
862962006140	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006141	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962006142	FtsX-like permease family; Region: FtsX; pfam02687
862962006143	Signal peptide predicted for BF638R1512 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.927 between residues 32 and 33
862962006144	4 probable transmembrane helices predicted for BF638R1512 by TMHMM2.0 at aa 21-43, 286-308, 342-364 and 393-415
862962006145	HMMPfam hit to PF02687, Predicted permease, score 1.5e-21
862962006146	FtsX-like permease family; Region: FtsX; pfam02687
862962006147	4 probable transmembrane helices predicted for BF638R1513 by TMHMM2.0 at aa 17-39, 291-313, 338-360 and 388-410
862962006148	HMMPfam hit to PF02687, Predicted permease, score 1.4e-07
862962006149	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006150	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006151	FtsX-like permease family; Region: FtsX; pfam02687
862962006152	4 probable transmembrane helices predicted for BF638R1514 by TMHMM2.0 at aa 21-43, 292-314, 341-363 and 398-420
862962006153	HMMPfam hit to PF02687, Predicted permease, score 1.3e-19
862962006154	FtsX-like permease family; Region: FtsX; pfam02687
862962006155	4 probable transmembrane helices predicted for BF638R1515 by TMHMM2.0 at aa 20-42, 289-311, 339-361 and 381-403
862962006156	HMMPfam hit to PF02687, Predicted permease, score 2.7e-10
862962006157	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962006158	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962006159	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.4e-10
862962006160	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.64
862962006161	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962006162	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962006163	Walker A/P-loop; other site
862962006164	ATP binding site [chemical binding]; other site
862962006165	Q-loop/lid; other site
862962006166	ABC transporter signature motif; other site
862962006167	Walker B; other site
862962006168	D-loop; other site
862962006169	H-loop/switch region; other site
862962006170	HMMPfam hit to PF00005, ABC transporter, score 1.5e-56
862962006171	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006172	PS00211 ABC transporters family signature.
862962006173	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006174	FtsX-like permease family; Region: FtsX; pfam02687
862962006175	Signal peptide predicted for BF638R1518 by SignalP 2.0 HMM (Signal peptide probability 0.958) with cleavage site probability 0.656 between residues 43 and 44
862962006176	4 probable transmembrane helices predicted for BF638R1518 by TMHMM2.0 at aa 21-43, 285-307, 337-359 and 385-407
862962006177	HMMPfam hit to PF02687, Predicted permease, score 3.6e-23
862962006178	FtsX-like permease family; Region: FtsX; pfam02687
862962006179	4 probable transmembrane helices predicted for BF638R1519 by TMHMM2.0 at aa 17-39, 292-314, 334-356 and 378-400
862962006180	HMMPfam hit to PF02687, Predicted permease, score 8.2e-06
862962006181	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962006182	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962006183	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962006184	Walker A/P-loop; other site
862962006185	ATP binding site [chemical binding]; other site
862962006186	Q-loop/lid; other site
862962006187	ABC transporter signature motif; other site
862962006188	Walker B; other site
862962006189	D-loop; other site
862962006190	H-loop/switch region; other site
862962006191	HMMPfam hit to PF00005, ABC transporter, score 3e-59
862962006192	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006193	PS00211 ABC transporters family signature.
862962006194	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
862962006195	Signal peptide predicted for BF638R1521 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.488 between residues 22 and 23
862962006196	1 probable transmembrane helix predicted for BF638R1521 by TMHMM2.0 at aa 5-23
862962006197	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006198	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006199	FtsX-like permease family; Region: FtsX; pfam02687
862962006200	Signal peptide predicted for BF638R1522 by SignalP 2.0 HMM (Signal peptide probability 0.695) with cleavage site probability 0.472 between residues 40 and 41
862962006201	4 probable transmembrane helices predicted for BF638R1522 by TMHMM2.0 at aa 17-39, 294-311, 345-367 and 394-416
862962006202	HMMPfam hit to PF02687, Predicted permease, score 6.2e-19
862962006203	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962006204	4 probable transmembrane helices predicted for BF638R1523 by TMHMM2.0 at aa 20-42, 288-310, 331-353 and 373-395
862962006205	HMMPfam hit to PF02687, Predicted permease, score 0.00076
862962006206	3 probable transmembrane helices predicted for BF638R1524 by TMHMM2.0 at aa 42-59, 74-93 and 404-426
862962006207	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
862962006208	PAS domain; Region: PAS; smart00091
862962006209	PAS domain; Region: PAS_9; pfam13426
862962006210	PAS fold; Region: PAS_3; pfam08447
862962006211	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962006212	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962006213	dimer interface [polypeptide binding]; other site
862962006214	phosphorylation site [posttranslational modification]
862962006215	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962006216	ATP binding site [chemical binding]; other site
862962006217	Mg2+ binding site [ion binding]; other site
862962006218	G-X-G motif; other site
862962006219	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006220	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.1e-23
862962006221	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.2e-36
862962006222	3 probable transmembrane helices predicted for BF638R1525 by TMHMM2.0 at aa 13-35, 45-63 and 70-92
862962006223	Signal peptide predicted for BF638R1526 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.924 between residues 19 and 20
862962006224	Outer membrane efflux protein; Region: OEP; pfam02321
862962006225	Outer membrane efflux protein; Region: OEP; pfam02321
862962006226	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0014
862962006227	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0011
862962006228	HMMPfam hit to PF00072, Response regulator receiver domain, score 5e-34
862962006229	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962006230	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962006231	active site
862962006232	phosphorylation site [posttranslational modification]
862962006233	intermolecular recognition site; other site
862962006234	dimerization interface [polypeptide binding]; other site
862962006235	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962006236	Walker A motif; other site
862962006237	ATP binding site [chemical binding]; other site
862962006238	Walker B motif; other site
862962006239	arginine finger; other site
862962006240	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962006241	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.3e-134
862962006242	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
862962006243	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
862962006244	PS00688 Sigma-54 interaction domain C-terminal part signature.
862962006245	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.9e-16
862962006246	HAMP domain; Region: HAMP; pfam00672
862962006247	dimerization interface [polypeptide binding]; other site
862962006248	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
862962006249	PAS domain; Region: PAS; smart00091
862962006250	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962006251	ATP binding site [chemical binding]; other site
862962006252	Mg2+ binding site [ion binding]; other site
862962006253	G-X-G motif; other site
862962006254	2 probable transmembrane helices predicted for BF638R1529 by TMHMM2.0 at aa 5-24 and 29-51
862962006255	HMMPfam hit to PF00672, HAMP domain, score 4e-07
862962006256	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8e-17
862962006257	aspartate 4-decarboxylase; Region: asp_4_decarbox; TIGR03801
862962006258	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962006259	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962006260	homodimer interface [polypeptide binding]; other site
862962006261	catalytic residue [active]
862962006262	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
862962006263	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962006264	TrkA-C domain; Region: TrkA_C; pfam02080
862962006265	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962006266	11 probable transmembrane helices predicted for BF638R1531 by TMHMM2.0 at aa 10-27, 34-56, 88-110, 115-137, 157-179, 391-408, 412-434, 447-469, 479-501, 508-530 and 545-564
862962006267	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 3.6e-67
862962006268	HMMPfam hit to PF02080, TrkA-C domain, score 0.00014
862962006269	HMMPfam hit to PF02080, TrkA-C domain, score 3.3e-11
862962006270	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 4.4e-67
862962006271	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
862962006272	8 probable transmembrane helices predicted for BF638R1532 by TMHMM2.0 at aa 2-19, 34-56, 76-98, 113-135, 142-164, 218-240, 247-269 and 279-301
862962006273	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962006274	non-specific DNA binding site [nucleotide binding]; other site
862962006275	salt bridge; other site
862962006276	sequence-specific DNA binding site [nucleotide binding]; other site
862962006277	HMMPfam hit to PF01381, Helix-turn-helix, score 4.7e-13
862962006278	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
862962006279	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962006280	similar to PS_6/PS_F lipopolysaccharide biosynthesis locus in BF9343
862962006281	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962006282	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 1.8e-62
862962006283	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962006284	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962006285	substrate binding site; other site
862962006286	tetramer interface; other site
862962006287	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5e-105
862962006288	PS00019 Actinin-type actin-binding domain signature 1.
862962006289	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
862962006290	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
862962006291	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
862962006292	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
862962006293	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
862962006294	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 7.9e-42
862962006295	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 1.8e-36
862962006296	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 2.3e-10
862962006297	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962006298	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962006299	NAD(P) binding site [chemical binding]; other site
862962006300	active site
862962006301	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 2.6e-116
862962006302	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
862962006303	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
862962006304	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 2.6e-99
862962006305	colanic acid exporter; Provisional; Region: PRK10459
862962006306	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
862962006307	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 2e-22
862962006308	11 probable transmembrane helices predicted for BF638R1546 by TMHMM2.0 at aa 45-67, 80-102, 112-130, 143-165, 169-191, 292-314, 318-340, 353-372, 376-398, 417-434 and 438-460
862962006309	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006310	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962006311	10 probable transmembrane helices predicted for BF638R1547 by TMHMM2.0 at aa 9-28, 48-70, 91-113, 123-145, 152-169, 174-193, 206-228, 238-257, 269-291 and 306-328
862962006312	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
862962006313	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962006314	inhibitor-cofactor binding pocket; inhibition site
862962006315	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962006316	catalytic residue [active]
862962006317	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 9.7e-91
862962006318	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006319	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
862962006320	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
862962006321	trimer interface [polypeptide binding]; other site
862962006322	active site
862962006323	substrate binding site [chemical binding]; other site
862962006324	CoA binding site [chemical binding]; other site
862962006325	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 22
862962006326	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 7.7
862962006327	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.12
862962006328	Signal peptide predicted for BF638R1551 by SignalP 2.0 HMM (Signal peptide probability 0.684) with cleavage site probability 0.467 between residues 41 and 42
862962006329	10 probable transmembrane helices predicted for BF638R1551 by TMHMM2.0 at aa 13-35, 50-72, 93-110, 133-155, 162-179, 183-205, 214-231, 241-258, 263-282 and 297-319
862962006330	HMMPfam hit to PF01757, Acyltransferase family, score 0.0014
862962006331	9 probable transmembrane helices predicted for BF638R1552 by TMHMM2.0 at aa 7-29, 97-119, 126-145, 155-177, 190-212, 232-254, 284-306, 310-329 and 336-354
862962006332	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962006333	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
862962006334	active site
862962006335	nucleotide binding site [chemical binding]; other site
862962006336	HIGH motif; other site
862962006337	KMSKS motif; other site
862962006338	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
862962006339	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962006340	HMMPfam hit to PF01467, Cytidylyltransferase, score 9.7e-19
862962006341	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 9.5e-28
862962006342	classical (c) SDRs; Region: SDR_c; cd05233
862962006343	short chain dehydrogenase; Validated; Region: PRK08264
862962006344	NAD(P) binding site [chemical binding]; other site
862962006345	active site
862962006346	HMMPfam hit to PF00106, short chain dehydrogenase, score 1.1e-06
862962006347	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
862962006348	classical (c) SDRs; Region: SDR_c; cd05233
862962006349	NAD(P) binding site [chemical binding]; other site
862962006350	active site
862962006351	HMMPfam hit to PF00106, short chain dehydrogenase, score 1.8e-39
862962006352	LicD family; Region: LicD; pfam04991
862962006353	HMMPfam hit to PF04991, LICD Protein Family, score 2.6e-46
862962006354	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962006355	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
862962006356	putative ADP-binding pocket [chemical binding]; other site
862962006357	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.2e-15
862962006358	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962006359	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
862962006360	putative ADP-binding pocket [chemical binding]; other site
862962006361	HMMPfam hit to PF00534, Glycosyl transferases group, score 2.2e-30
862962006363	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962006364	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
862962006365	putative ADP-binding pocket [chemical binding]; other site
862962006366	HMMPfam hit to PF00534, Glycosyl transferases group, score 6.2e-30
862962006367	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962006368	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962006369	NAD(P) binding site [chemical binding]; other site
862962006370	active site
862962006371	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006372	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
862962006373	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
862962006374	Mg++ binding site [ion binding]; other site
862962006375	putative catalytic motif [active]
862962006376	putative substrate binding site [chemical binding]; other site
862962006377	11 probable transmembrane helices predicted for BF638R1563 by TMHMM2.0 at aa 4-21, 41-58, 62-79, 91-108, 112-131, 138-160, 164-181, 188-210, 217-239, 260-282 and 286-305
862962006378	HMMPfam hit to PF00953, Glycosyl transferase, score 1.4e-08
862962006379	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006380	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
862962006381	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
862962006382	homodimer interface [polypeptide binding]; other site
862962006383	oligonucleotide binding site [chemical binding]; other site
862962006384	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962006385	IHF - DNA interface [nucleotide binding]; other site
862962006386	IHF dimer interface [polypeptide binding]; other site
862962006387	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 4.1e-27
862962006388	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
862962006389	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
862962006390	minor groove reading motif; other site
862962006391	helix-hairpin-helix signature motif; other site
862962006392	substrate binding pocket [chemical binding]; other site
862962006393	active site
862962006394	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
862962006395	DNA binding and oxoG recognition site [nucleotide binding]
862962006396	HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 4.9e-19
862962006397	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 9e-06
862962006398	Sulfatase; Region: Sulfatase; cl17466
862962006399	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962006400	Signal peptide predicted for BF638R1568 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.440 between residues 19 and 20
862962006401	HMMPfam hit to PF00884, Sulfatase, score 5.6e-29
862962006402	PS00523 Sulfatases signature 1.
862962006403	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
862962006404	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
862962006405	dimer interface [polypeptide binding]; other site
862962006406	ssDNA binding site [nucleotide binding]; other site
862962006407	tetramer (dimer of dimers) interface [polypeptide binding]; other site
862962006408	HMMPfam hit to PF00436, Single-strand binding protein family, score 1.1e-32
862962006409	PS00735 Single-strand binding protein family signature 1.
862962006410	gliding motility-associated protein GldE; Region: GldE; TIGR03520
862962006411	Domain of unknown function DUF21; Region: DUF21; pfam01595
862962006412	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
862962006413	Transporter associated domain; Region: CorC_HlyC; smart01091
862962006414	3 probable transmembrane helices predicted for BF638R1570 by TMHMM2.0 at aa 21-43, 82-104 and 109-131
862962006415	HMMPfam hit to PF01595, Domain of unknown function DUF21, score 3.4e-29
862962006416	HMMPfam hit to PF00571, CBS domain, score 7.1e-05
862962006417	HMMPfam hit to PF00571, CBS domain, score 1.7e-09
862962006418	HMMPfam hit to PF03471, Transporter associated domain, score 3.2e-20
862962006419	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
862962006420	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
862962006421	Alpha-2-macroglobulin family; Region: A2M; pfam00207
862962006422	Signal peptide predicted for BF638R1572 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.631 between residues 20 and 21
862962006423	1 probable transmembrane helix predicted for BF638R1572 by TMHMM2.0 at aa 5-24
862962006424	Protein of unknown function (DUF1271); Region: DUF1271; pfam06902
862962006425	HMMPfam hit to PF06902, Protein of unknown function (DUF1271), score 3.5e-34
862962006426	Predicted acetyltransferase [General function prediction only]; Region: COG2388
862962006427	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962006428	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; cl01930
862962006429	Signal peptide predicted for BF638R1575 by SignalP 2.0 HMM (Signal peptide probability 0.743) with cleavage site probability 0.254 between residues 20 and 21
862962006430	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006431	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962006432	Signal peptide predicted for BF638R1576 by SignalP 2.0 HMM (Signal peptide probability 0.937) with cleavage site probability 0.493 between residues 47 and 48
862962006433	1 probable transmembrane helix predicted for BF638R1576 by TMHMM2.0 at aa 7-29
862962006434	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006435	Signal peptide predicted for BF638R1577 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.513 between residues 27 and 28
862962006436	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006437	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962006438	Signal peptide predicted for BF638R1578 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.890 between residues 19 and 20
862962006439	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006440	Signal peptide predicted for BF638R1579 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.795 between residues 35 and 36
862962006441	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006442	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
862962006443	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006444	1 probable transmembrane helix predicted for BF638R1580 by TMHMM2.0 at aa 20-37
862962006445	Signal peptide predicted for BF638R1580 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.391 between residues 36 and 37
862962006446	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
862962006447	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962006448	HMMPfam hit to PF00593, TonB dependent receptor, score 6.6e-22
862962006449	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2e-11
862962006450	Signal peptide predicted for BF638R1581 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.582 between residues 28 and 29
862962006451	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962006452	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
862962006453	Signal peptide predicted for BF638R1584 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 26 and 27
862962006454	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006455	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962006456	dimer interface [polypeptide binding]; other site
862962006457	phosphorylation site [posttranslational modification]
862962006458	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962006459	ATP binding site [chemical binding]; other site
862962006460	Mg2+ binding site [ion binding]; other site
862962006461	G-X-G motif; other site
862962006462	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.8e-34
862962006463	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-16
862962006464	2 probable transmembrane helices predicted for BF638R1587 by TMHMM2.0 at aa 34-52 and 189-206
862962006465	Signal peptide predicted for BF638R1587 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.590 between residues 51 and 52
862962006466	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006467	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962006468	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962006469	active site
862962006470	phosphorylation site [posttranslational modification]
862962006471	intermolecular recognition site; other site
862962006472	dimerization interface [polypeptide binding]; other site
862962006473	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962006474	DNA binding site [nucleotide binding]
862962006475	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.1e-25
862962006476	HMMPfam hit to PF00072, Response regulator receiver domain, score 9.9e-37
862962006477	Signal peptide predicted for BF638R1590 by SignalP 2.0 HMM (Signal peptide probability 0.957) with cleavage site probability 0.444 between residues 38 and 39
862962006478	1 probable transmembrane helix predicted for BF638R1590 by TMHMM2.0 at aa 13-30
862962006479	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
862962006480	Signal peptide predicted for BF638R1591 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.576 between residues 31 and 32
862962006481	1 probable transmembrane helix predicted for BF638R1591 by TMHMM2.0 at aa 13-30
862962006482	Signal peptide predicted for BF638R1592 by SignalP 2.0 HMM (Signal peptide probability 0.875) with cleavage site probability 0.649 between residues 19 and 20
862962006483	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006484	Domain of unknown function (DUF3805); Region: DUF3805; pfam12712
862962006485	Domain of unknown function (DUF3806); Region: DUF3806; pfam12713
862962006486	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
862962006487	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962006488	Walker A/P-loop; other site
862962006489	ATP binding site [chemical binding]; other site
862962006490	ABC transporter signature motif; other site
862962006491	Walker B; other site
862962006492	D-loop; other site
862962006493	H-loop/switch region; other site
862962006494	ABC transporter; Region: ABC_tran_2; pfam12848
862962006495	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962006496	HMMPfam hit to PF00005, ABC transporter, score 1.3e-40
862962006497	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006498	PS00211 ABC transporters family signature.
862962006499	HMMPfam hit to PF00005, ABC transporter, score 2.5e-34
862962006500	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006501	histidinol-phosphatase; Provisional; Region: PRK07328
862962006502	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
862962006503	active site
862962006504	dimer interface [polypeptide binding]; other site
862962006505	HMMPfam hit to PF02231, PHP domain N-terminal region, score 0.048
862962006506	HMMPfam hit to PF02811, PHP domain C-terminal region, score 0.028
862962006507	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
862962006508	active site
862962006509	catalytic residues [active]
862962006510	1 probable transmembrane helix predicted for BF638R1597 by TMHMM2.0 at aa 21-40
862962006511	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006512	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 9.8e-11
862962006513	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
862962006514	substrate binding site [chemical binding]; other site
862962006515	catalytic residues [active]
862962006516	HMMPfam hit to PF02278, Polysaccharide lyase family 8, super-sandwic, score 6.1e-31
862962006517	Signal peptide predicted for BF638R1599 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.383 between residues 19 and 20
862962006518	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006519	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
862962006520	substrate binding site [chemical binding]; other site
862962006521	trimer interface [polypeptide binding]; other site
862962006522	hexamer (dimer of trimers) interface [polypeptide binding]; other site
862962006523	Mn binding site [ion binding]; other site
862962006524	aspartate aminotransferase; Provisional; Region: PRK07568
862962006525	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962006526	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962006527	homodimer interface [polypeptide binding]; other site
862962006528	catalytic residue [active]
862962006529	HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.1e-21
862962006530	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
862962006531	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006532	FtsX-like permease family; Region: FtsX; pfam02687
862962006533	4 probable transmembrane helices predicted for BF638R1602 by TMHMM2.0 at aa 49-71, 303-325, 350-372 and 403-425; 4 probable transmembrane helices predicted for BF638R1603 by TMHMM2.0 at aa 47-69, 301-323, 348-370 and 401-423
862962006534	HMMPfam hit to PF02687, Predicted permease, score 2e-24
862962006535	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962006536	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_e; cd04192
862962006537	2 probable transmembrane helices predicted for BF638R1604 by TMHMM2.0 at aa 10-32 and 304-326
862962006538	HMMPfam hit to PF00535, Glycosyl transferase, score 4.3e-23
862962006539	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
862962006540	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 3.1e-29
862962006541	8 probable transmembrane helices predicted for BF638R1605 by TMHMM2.0 at aa 5-22, 26-43, 56-78, 134-156, 192-214, 219-241, 246-268 and 288-320
862962006542	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
862962006543	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962006544	dimer interface [polypeptide binding]; other site
862962006545	phosphorylation site [posttranslational modification]
862962006546	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962006547	ATP binding site [chemical binding]; other site
862962006548	Mg2+ binding site [ion binding]; other site
862962006549	G-X-G motif; other site
862962006550	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 6.1e-31
862962006551	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0013
862962006552	2 probable transmembrane helices predicted for BF638R1606 by TMHMM2.0 at aa 7-29 and 33-52
862962006553	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962006554	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962006555	active site
862962006556	phosphorylation site [posttranslational modification]
862962006557	intermolecular recognition site; other site
862962006558	dimerization interface [polypeptide binding]; other site
862962006559	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962006560	Walker A motif; other site
862962006561	ATP binding site [chemical binding]; other site
862962006562	Walker B motif; other site
862962006563	arginine finger; other site
862962006564	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962006565	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.8e-16
862962006566	PS00688 Sigma-54 interaction domain C-terminal part signature.
862962006567	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 7.2e-132
862962006568	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-24
862962006569	Outer membrane efflux protein; Region: OEP; pfam02321
862962006570	Outer membrane efflux protein; Region: OEP; pfam02321
862962006571	Signal peptide predicted for BF638R1608 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.802 between residues 19 and 20
862962006572	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.7e-20
862962006573	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.00084
862962006574	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962006575	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962006576	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962006577	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962006578	1 probable transmembrane helix predicted for BF638R1609 by TMHMM2.0 at aa 17-34
862962006579	HMMPfam hit to PF00529, HlyD family secretion protein, score 2e-05
862962006580	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962006581	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962006582	Walker A/P-loop; other site
862962006583	ATP binding site [chemical binding]; other site
862962006584	Q-loop/lid; other site
862962006585	ABC transporter signature motif; other site
862962006586	Walker B; other site
862962006587	D-loop; other site
862962006588	H-loop/switch region; other site
862962006589	HMMPfam hit to PF00005, ABC transporter, score 2.5e-63
862962006590	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006591	PS00211 ABC transporters family signature.
862962006592	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006593	FtsX-like permease family; Region: FtsX; pfam02687
862962006594	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962006595	FtsX-like permease family; Region: FtsX; pfam02687
862962006596	Signal peptide predicted for BF638R1611 by SignalP 2.0 HMM (Signal peptide probability 0.717) with cleavage site probability 0.416 between residues 34 and 35
862962006597	8 probable transmembrane helices predicted for BF638R1611 by TMHMM2.0 at aa 21-43, 286-308, 338-360, 380-402, 429-451, 680-702, 732-754 and 769-788
862962006598	PS00211 ABC transporters family signature.
862962006599	HMMPfam hit to PF02687, Predicted permease, score 7.5e-22
862962006600	HMMPfam hit to PF02687, Predicted permease, score 7.5e-10
862962006601	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006602	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006603	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006604	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
862962006605	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
862962006606	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962006607	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreducta, score 2.3e-37
862962006608	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
862962006609	AAA domain; Region: AAA_26; pfam13500
862962006610	Protein of unknown function (DUF452); Region: DUF452; cl01062
862962006611	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
862962006612	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962006613	S-adenosylmethionine binding site [chemical binding]; other site
862962006614	HMMPfam hit to PF04301, Protein of unknown function (DUF452), score 2.4e-41
862962006615	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
862962006616	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
862962006617	substrate-cofactor binding pocket; other site
862962006618	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962006619	catalytic residue [active]
862962006620	HMMPfam hit to PF00155, Aminotransferase class I and II, score 9.5e-37
862962006621	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962006622	biotin synthase; Region: bioB; TIGR00433
862962006623	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962006624	FeS/SAM binding site; other site
862962006625	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
862962006626	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
862962006627	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06173
862962006628	inhibitor-cofactor binding pocket; inhibition site
862962006629	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962006630	catalytic residue [active]
862962006631	HMMPfam hit to PF00202, Aminotransferase class-III, score 3.9e-164
862962006632	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
862962006633	HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 1.8e-31
862962006634	HMMPfam hit to PF04055, Radical SAM superfamily, score 4.5e-21
862962006635	Signal peptide predicted for BF638R1619 by SignalP 2.0 HMM (Signal peptide probability 0.623) with cleavage site probability 0.384 between residues 39 and 40
862962006636	1 probable transmembrane helix predicted for BF638R1619 by TMHMM2.0 at aa 21-38
862962006637	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962006638	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962006639	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962006640	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962006641	Signal peptide predicted for BF638R1620 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.585 between residues 21 and 22
862962006642	1 probable transmembrane helix predicted for BF638R1620 by TMHMM2.0 at aa 7-24
862962006643	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.6e-23
862962006644	PS00152 ATP synthase alpha and beta subunits signature.
862962006645	HMMPfam hit to PF00593, TonB dependent receptor, score 7.1e-19
862962006646	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962006647	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006648	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
862962006649	L-lactate permease; Region: Lactate_perm; cl00701
862962006650	HMMPfam hit to PF02652, L-lactate permease, score 7.3e-131
862962006651	13 probable transmembrane helices predicted for BF638R1622 by TMHMM2.0 at aa 2-20, 30-47, 54-76, 114-136, 143-165, 175-197, 210-228, 233-252, 272-294, 319-341, 364-386, 390-412 and 476-498
862962006652	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
862962006653	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962006654	ligand binding site [chemical binding]; other site
862962006655	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006656	binding surface
862962006657	TPR motif; other site
862962006658	Signal peptide predicted for BF638R1623 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.969 between residues 20 and 21
862962006659	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962006660	Signal peptide predicted for BF638R1624 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 24 and 25
862962006661	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
862962006662	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
862962006663	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
862962006664	HMMPfam hit to PF01039, Carboxyl transferase domain, score 5.9e-290
862962006665	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
862962006666	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962006667	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962006668	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
862962006669	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 3.7e-41
862962006670	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.6e-97
862962006671	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962006672	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 1.6e-65
862962006673	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962006674	carboxyltransferase (CT) interaction site; other site
862962006675	biotinylation site [posttranslational modification]; other site
862962006676	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.7e-21
862962006677	PS00188 Biotin-requiring enzymes attachment site.
862962006678	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
862962006679	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
862962006680	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
862962006681	active site
862962006682	HMMPfam hit to PF01979, Amidohydrolase family, score 2.4e-15
862962006683	Signal peptide predicted for BF638R1631 by SignalP 2.0 HMM (Signal peptide probability 0.918) with cleavage site probability 0.555 between residues 18 and 19
862962006684	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006685	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006686	Signal peptide predicted for BF638R1632 by SignalP 2.0 HMM (Signal peptide probability 0.708) with cleavage site probability 0.651 between residues 23 and 24
862962006687	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006688	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
862962006689	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
862962006690	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
862962006691	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
862962006692	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.4e-88
862962006693	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
862962006694	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 3.1e-32
862962006695	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
862962006696	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 4.5e-19
862962006697	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
862962006698	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
862962006699	E3 interaction surface; other site
862962006700	lipoyl attachment site [posttranslational modification]; other site
862962006701	e3 binding domain; Region: E3_binding; pfam02817
862962006702	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
862962006703	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.1e-27
862962006704	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
862962006705	HMMPfam hit to PF02817, e3 binding domain, score 6e-09
862962006706	HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 1.3e-91
862962006707	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
862962006708	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
862962006709	tetramer interface [polypeptide binding]; other site
862962006710	TPP-binding site [chemical binding]; other site
862962006711	heterodimer interface [polypeptide binding]; other site
862962006712	phosphorylation loop region [posttranslational modification]
862962006713	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
862962006714	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
862962006715	PYR/PP interface [polypeptide binding]; other site
862962006716	dimer interface [polypeptide binding]; other site
862962006717	TPP binding site [chemical binding]; other site
862962006718	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
862962006719	HMMPfam hit to PF00676, Dehydrogenase E1 component, score 1.9e-40
862962006720	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 3.6e-25
862962006721	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 1.1e-50
862962006722	flavodoxin FldA; Validated; Region: PRK09267
862962006723	HMMPfam hit to PF00258, Flavodoxin, score 7.7e-27
862962006724	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
862962006725	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962006726	S-adenosylmethionine binding site [chemical binding]; other site
862962006727	HMMPfam hit to PF06325, Ribosomal protein L11 methyltransferase (Prm, score 8.5e-21
862962006728	Signal peptide predicted for BF638R1640 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.906 between residues 52 and 53
862962006729	2 probable transmembrane helices predicted for BF638R1640 by TMHMM2.0 at aa 5-24 and 36-55
862962006730	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962006731	Peptidase C10 family; Region: Peptidase_C10; pfam01640
862962006732	Signal peptide predicted for BF638R1641 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.474 between residues 22 and 23
862962006733	1 probable transmembrane helix predicted for BF638R1641 by TMHMM2.0 at aa 5-27
862962006734	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006735	Signal peptide predicted for BF638R1642 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.724 between residues 19 and 20
862962006736	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006737	Signal peptide predicted for BF638R1644 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.957 between residues 33 and 34
862962006738	1 probable transmembrane helix predicted for BF638R1644 by TMHMM2.0 at aa 17-34
862962006739	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
862962006740	Signal peptide predicted for BF638R1645 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.976 between residues 20 and 21
862962006741	PS00308 Legume lectins alpha-chain signature.
862962006742	Signal peptide predicted for BF638R1646 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.601 between residues 22 and 23
862962006743	MAC/Perforin domain; Region: MACPF; pfam01823
862962006744	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006745	HMMPfam hit to PF01823, MAC/Perforin domain, score 1.6e-05
862962006746	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
862962006747	nucleoside/Zn binding site; other site
862962006748	dimer interface [polypeptide binding]; other site
862962006749	catalytic motif [active]
862962006750	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminase, score 2.3e-38
862962006751	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
862962006752	Signal peptide predicted for BF638R1648 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.851 between residues 18 and 19
862962006753	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
862962006754	Signal peptide predicted for BF638R1649 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.986 between residues 23 and 24
862962006755	1 probable transmembrane helix predicted for BF638R1650 by TMHMM2.0 at aa 72-91
862962006756	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962006757	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962006758	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962006759	DNA binding residues [nucleotide binding]
862962006760	HMMPfam hit to PF04545, Sigma-70, region, score 4.5e-12
862962006761	HMMPfam hit to PF04542, Sigma-70 region, score 5.1e-13
862962006762	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
862962006763	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962006764	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
862962006765	HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.0016
862962006766	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 2.6e-32
862962006767	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
862962006768	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
862962006769	substrate binding pocket [chemical binding]; other site
862962006770	membrane-bound complex binding site; other site
862962006771	hinge residues; other site
862962006772	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2.3e-14
862962006773	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
862962006774	Signal peptide predicted for BF638R1654 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.899 between residues 24 and 25
862962006775	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
862962006776	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
862962006777	HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductas, score 4.3e-26
862962006778	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
862962006779	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
862962006780	TPP-binding site [chemical binding]; other site
862962006781	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 5.6e-63
862962006782	2 probable transmembrane helices predicted for BF638R1657 by TMHMM2.0 at aa 9-28 and 32-54
862962006783	Signal peptide predicted for BF638R1657 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.754 between residues 28 and 29
862962006784	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
862962006785	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
862962006786	dimer interface [polypeptide binding]; other site
862962006787	PYR/PP interface [polypeptide binding]; other site
862962006788	TPP binding site [chemical binding]; other site
862962006789	substrate binding site [chemical binding]; other site
862962006790	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
862962006791	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 0.0096
862962006792	HMMPfam hit to PF01855, Pyruvate flavodoxin/ferredoxin oxidor, score 6.7e-64
862962006793	Ferredoxin [Energy production and conversion]; Region: COG1146
862962006794	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
862962006795	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 3.6e-05
862962006796	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962006797	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.3e-07
862962006798	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962006799	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006800	TPR motif; other site
862962006801	binding surface
862962006802	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962006803	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 5.5e-11; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 4e-09
862962006804	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
862962006805	HMMPfam hit to PF02502, Ribose/Galactose Isomerase, score 1.1e-35
862962006806	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
862962006807	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
862962006808	TPP-binding site [chemical binding]; other site
862962006809	dimer interface [polypeptide binding]; other site
862962006810	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
862962006811	PYR/PP interface [polypeptide binding]; other site
862962006812	dimer interface [polypeptide binding]; other site
862962006813	TPP binding site [chemical binding]; other site
862962006814	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
862962006815	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 0.00076
862962006816	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 3.7e-35
862962006817	PS00802 Transketolase signature 2.
862962006818	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006819	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 2.8e-107
862962006820	PS00801 Transketolase signature 1.
862962006821	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
862962006822	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
862962006823	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
862962006824	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
862962006825	HMMPfam hit to PF00288, GHMP kinases putative ATP-binding protei, score 1.7e-39
862962006826	PS00012 Phosphopantetheine attachment site.
862962006827	PS00106 Galactokinase signature.
862962006828	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962006829	putative substrate translocation pore; other site
862962006830	glucose/galactose transporter; Region: gluP; TIGR01272
862962006831	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006832	12 probable transmembrane helices predicted for BF638R1664 by TMHMM2.0 at aa 7-29, 44-66, 78-97, 107-129, 150-172, 182-201, 228-250, 270-292, 305-327, 347-369, 381-403 and 408-430
862962006833	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-18
862962006834	Signal peptide predicted for BF638R1664 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.791 between residues 27 and 28
862962006835	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
862962006836	active site
862962006837	catalytic residues [active]
862962006838	HMMPfam hit to PF01263, Aldose 1-epimerase, score 1.8e-109
862962006839	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
862962006840	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
862962006841	ligand binding site [chemical binding]; other site
862962006842	HMMPfam hit to PF01238, Phosphomannose isomerase type I, score 7.5e-09
862962006843	2 probable transmembrane helices predicted for BF638R1668 by TMHMM2.0 at aa 38-60 and 75-97
862962006844	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962006845	1 probable transmembrane helix predicted for BF638R1669 by TMHMM2.0 at aa 4-26
862962006846	Signal peptide predicted for BF638R1669 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.328 between residues 21 and 22
862962006847	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
862962006848	DEAD-like helicases superfamily; Region: DEXDc; smart00487
862962006849	ATP binding site [chemical binding]; other site
862962006850	Mg++ binding site [ion binding]; other site
862962006851	motif III; other site
862962006852	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962006853	nucleotide binding region [chemical binding]; other site
862962006854	ATP-binding site [chemical binding]; other site
862962006855	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1e-31
862962006856	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 9.2e-72
862962006857	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
862962006858	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006859	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
862962006860	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
862962006861	putative NAD(P) binding site [chemical binding]; other site
862962006862	homodimer interface [polypeptide binding]; other site
862962006863	homotetramer interface [polypeptide binding]; other site
862962006864	active site
862962006865	HMMPfam hit to PF00106, short chain dehydrogenase, score 8.8e-59
862962006866	PS00061 Short-chain dehydrogenases/reductases family signature.
862962006867	Sporulation related domain; Region: SPOR; cl10051
862962006868	Signal peptide predicted for BF638R1672 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.306 between residues 22 and 23
862962006869	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
862962006871	Methyltransferase domain; Region: Methyltransf_31; pfam13847
862962006872	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962006873	S-adenosylmethionine binding site [chemical binding]; other site
862962006874	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962006875	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962006876	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962006877	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 1.2e-09
862962006878	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 5.4e-07
862962006879	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1e-57
862962006880	Signal peptide predicted for BF638R1674 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.520 between residues 21 and 22
862962006881	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
862962006882	active site
862962006883	HMMPfam hit to PF00459, Inositol monophosphatase family, score 1.2e-46
862962006884	PS00629 Inositol monophosphatase family signature 1.
862962006885	12 probable transmembrane helices predicted for BF638R1677 by TMHMM2.0 at aa 4-25, 32-49, 105-127, 140-162, 177-199, 319-341, 351-368, 381-400, 415-432, 439-457, 462-484 and 497-519
862962006886	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
862962006887	transmembrane helices; other site
862962006888	TrkA-C domain; Region: TrkA_C; pfam02080
862962006889	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
862962006890	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
862962006891	HMMPfam hit to PF02080, TrkA-C domain, score 4.6e-06
862962006892	PS01271 Sodium:sulfate symporter family signature.
862962006893	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
862962006894	ligand-binding site [chemical binding]; other site
862962006895	HMMPfam hit to PF01583, Adenylylsulphate kinase, score 8.9e-91
862962006896	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006897	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
862962006898	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
862962006899	Active Sites [active]
862962006900	HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 1.1e-82
862962006901	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
862962006902	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
862962006903	CysD dimerization site [polypeptide binding]; other site
862962006904	G1 box; other site
862962006905	putative GEF interaction site [polypeptide binding]; other site
862962006906	GTP/Mg2+ binding site [chemical binding]; other site
862962006907	Switch I region; other site
862962006908	G2 box; other site
862962006909	G3 box; other site
862962006910	Switch II region; other site
862962006911	G4 box; other site
862962006912	G5 box; other site
862962006913	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
862962006914	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
862962006915	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.2e-68
862962006916	PS00017 ATP/GTP-binding site motif A (P-loop).
862962006917	PS00301 GTP-binding elongation factors signature.
862962006918	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962006919	HMMPfam hit to PF03144, Elongation factor Tu domain, score 5e-07
862962006920	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
862962006921	Signal peptide predicted for BF638R1682 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.985 between residues 23 and 24
862962006922	Cupin domain; Region: Cupin_2; pfam07883
862962006923	HMMPfam hit to PF07883, Cupin domain, score 0.0013
862962006924	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962006925	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962006926	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962006927	ligand binding site [chemical binding]; other site
862962006928	HMMPfam hit to PF00691, OmpA family, score 3.4e-10
862962006929	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006930	Signal peptide predicted for BF638R1684 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.886 between residues 21 and 22
862962006931	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962006932	1 probable transmembrane helix predicted for BF638R1685 by TMHMM2.0 at aa 9-31
862962006933	Signal peptide predicted for BF638R1685 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.802 between residues 24 and 25
862962006934	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962006935	PS00678 Trp-Asp (WD) repeats signature.
862962006936	Signal peptide predicted for BF638R1686 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.764 between residues 30 and 31
862962006937	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006938	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962006939	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962006940	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
862962006941	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962006942	active site
862962006943	DNA binding site [nucleotide binding]
862962006944	Int/Topo IB signature motif; other site
862962006945	HMMPfam hit to PF00589, Phage integrase family, score 3.3e-17
862962006946	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962006947	Domain of unknown function (DUF3869); Region: DUF3869; pfam12985
862962006948	Signal peptide predicted for BF638R1690 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.430 between residues 33 and 34
862962006949	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006950	Signal peptide predicted for BF638R1691 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.918 between residues 22 and 23
862962006951	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962006952	Signal peptide predicted for BF638R1692 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.923 between residues 19 and 20
862962006953	1 probable transmembrane helix predicted for BF638R1692 by TMHMM2.0 at aa 5-27
862962006954	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962006955	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962006956	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962006957	ligand binding site [chemical binding]; other site
862962006958	Signal peptide predicted for BF638R1693 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.939 between residues 20 and 21
862962006959	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006960	HMMPfam hit to PF00691, OmpA family, score 1.5e-10
862962006961	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
862962006962	HMMPfam hit to PF03652, Uncharacterised protein family (UPF0081), score 4.3e-38
862962006963	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
862962006964	active site
862962006965	catalytic residues [active]
862962006966	metal binding site [ion binding]; metal-binding site
862962006967	HMMPfam hit to PF01327, Polypeptide deformylase, score 1.9e-48
862962006968	Signal peptide predicted for BF638R1696 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.618 between residues 23 and 24
862962006969	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962006970	Signal peptide predicted for BF638R1697 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 28 and 29
862962006971	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006972	TPR motif; other site
862962006973	binding surface
862962006974	TPR repeat; Region: TPR_11; pfam13414
862962006975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006976	binding surface
862962006977	TPR repeat; Region: TPR_11; pfam13414
862962006978	TPR motif; other site
862962006979	TPR repeat; Region: TPR_11; pfam13414
862962006980	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006981	binding surface
862962006982	TPR motif; other site
862962006983	TPR repeat; Region: TPR_11; pfam13414
862962006984	TPR repeat; Region: TPR_11; pfam13414
862962006985	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006986	binding surface
862962006987	TPR motif; other site
862962006988	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962006989	TPR motif; other site
862962006990	TPR repeat; Region: TPR_11; pfam13414
862962006991	binding surface
862962006992	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.023; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.28
862962006993	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 4e-06; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.4e-07
862962006994	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.068; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.14
862962006995	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.01; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0061
862962006996	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00023; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0018
862962006997	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00016; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0006
862962006998	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.9e-05; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.014
862962006999	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.001; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00094
862962007000	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.11; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.3
862962007001	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3.9e-07; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 7.5e-10
862962007002	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1
862962007003	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
862962007004	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
862962007005	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
862962007006	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
862962007007	active site
862962007008	dimer interface [polypeptide binding]; other site
862962007009	motif 1; other site
862962007010	motif 2; other site
862962007011	motif 3; other site
862962007012	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
862962007013	anticodon binding site; other site
862962007014	HMMPfam hit to PF02824, TGS domain, score 8.8e-08
862962007015	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.7e-45
862962007016	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962007017	HMMPfam hit to PF03129, Anticodon binding domain, score 1.9e-29
862962007018	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
862962007019	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
862962007020	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
862962007021	HMMPfam hit to PF05198, Translation initiation factor IF-3, N-termin, score 4.6e-36
862962007022	PS00938 Initiation factor 3 signature.
862962007023	HMMPfam hit to PF00707, Translation initiation factor IF-3, C-termin, score 5.9e-39
862962007024	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
862962007025	Signal peptide predicted for BF638R1700 by SignalP 2.0 HMM (Signal peptide probability 0.670) with cleavage site probability 0.531 between residues 58 and 59
862962007026	HMMPfam hit to PF01632, Ribosomal protein L35, score 3.3e-25
862962007027	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
862962007028	23S rRNA binding site [nucleotide binding]; other site
862962007029	L21 binding site [polypeptide binding]; other site
862962007030	L13 binding site [polypeptide binding]; other site
862962007031	HMMPfam hit to PF00453, Ribosomal protein L20, score 4.2e-43
862962007032	Flavodoxin domain; Region: Flavodoxin_5; cl17428
862962007033	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
862962007034	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007035	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 7.4e-05
862962007036	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962007037	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0007
862962007038	PS00086 Cytochrome P450 cysteine heme-iron ligand signature.
862962007039	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962007040	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962007041	active site
862962007042	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 3.9e-06
862962007043	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
862962007044	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962007045	acyl-activating enzyme (AAE) consensus motif; other site
862962007046	AMP binding site [chemical binding]; other site
862962007047	active site
862962007048	CoA binding site [chemical binding]; other site
862962007049	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
862962007050	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
862962007051	HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductas, score 1.6e-27
862962007052	1 probable transmembrane helix predicted for BF638R1705 by TMHMM2.0 at aa 5-27
862962007053	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
862962007054	dimer interface [polypeptide binding]; other site
862962007055	PYR/PP interface [polypeptide binding]; other site
862962007056	TPP binding site [chemical binding]; other site
862962007057	substrate binding site [chemical binding]; other site
862962007058	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
862962007059	TPP-binding site; other site
862962007060	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 2.6e-47
862962007061	PS00398 Site-specific recombinases signature 2.
862962007062	YceG-like family; Region: YceG; pfam02618
862962007063	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
862962007064	dimerization interface [polypeptide binding]; other site
862962007065	HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 1.5e-48
862962007066	1 probable transmembrane helix predicted for BF638R1707 by TMHMM2.0 at aa 9-31
862962007067	Signal peptide predicted for BF638R1707 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.869 between residues 24 and 25
862962007068	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
862962007069	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
862962007070	active site
862962007071	substrate binding site [chemical binding]; other site
862962007072	Mg2+ binding site [ion binding]; other site
862962007073	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 1.5e-64
862962007074	Signal peptide predicted for BF638R1708 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.242 between residues 43 and 44
862962007075	1 probable transmembrane helix predicted for BF638R1708 by TMHMM2.0 at aa 20-37
862962007076	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962007077	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962007078	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962007079	HMMPfam hit to PF07523, Bacterial Ig-like domain (group 3), score 0.00041
862962007080	HMMPfam hit to PF07523, Bacterial Ig-like domain (group 3), score 0.011
862962007081	Signal peptide predicted for BF638R1709 by SignalP 2.0 HMM (Signal peptide probability 0.911) with cleavage site probability 0.569 between residues 23 and 24
862962007082	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007083	putative polysaccharide biosynthesis cluster
862962007084	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
862962007085	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
862962007086	NAD(P) binding site [chemical binding]; other site
862962007087	homodimer interface [polypeptide binding]; other site
862962007088	substrate binding site [chemical binding]; other site
862962007089	active site
862962007090	Signal peptide predicted for BF638R1710 by SignalP 2.0 HMM (Signal peptide probability 0.896) with cleavage site probability 0.379 between residues 46 and 47
862962007091	4 probable transmembrane helices predicted for BF638R1710 by TMHMM2.0 at aa 19-41, 45-67, 88-110 and 115-137
862962007092	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 3.6e-161
862962007093	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
862962007094	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
862962007095	SLBB domain; Region: SLBB; pfam10531
862962007096	SLBB domain; Region: SLBB; pfam10531
862962007097	SLBB domain; Region: SLBB; pfam10531
862962007098	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
862962007099	Signal peptide predicted for BF638R1711 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 20 and 21
862962007100	HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 7.8e-15
862962007101	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
862962007102	HMMPfam hit to PF02706, Chain length determinant protein, score 0.00022
862962007103	2 probable transmembrane helices predicted for BF638R1712 by TMHMM2.0 at aa 34-53 and 338-357
862962007104	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962007105	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
862962007106	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
862962007107	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
862962007108	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
862962007109	nucleotide binding site [chemical binding]; other site
862962007110	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
862962007111	HMMPfam hit to PF00480, ROK family, score 4.6e-25
862962007112	PS01125 ROK family signature.
862962007113	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007114	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
862962007115	Class I aldolases; Region: Aldolase_Class_I; cl17187
862962007116	catalytic residue [active]
862962007117	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 3.2e-24
862962007118	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962007119	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
862962007120	dimerization interface [polypeptide binding]; other site
862962007121	putative active cleft [active]
862962007122	HMMPfam hit to PF07221, N-acylglucosamine 2-epimerase (GlcNAc, score 4.4e-13
862962007123	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962007124	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962007125	putative substrate translocation pore; other site
862962007126	12 probable transmembrane helices predicted for BF638R1718 by TMHMM2.0 at aa 7-29, 49-71, 78-100, 104-126, 138-160, 164-186, 217-239, 259-281, 294-313, 317-334, 355-372 and 382-404
862962007127	HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00014
862962007128	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.4e-47
862962007129	PS00217 Sugar transport proteins signature 2.
862962007130	Domain of unknown function (DUF386); Region: DUF386; cl01047
862962007131	HMMPfam hit to PF04074, Domain of unknown function (DUF386), score 4.8e-35
862962007132	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007133	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007134	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007135	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962007136	Signal peptide predicted for BF638R1720 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 19 and 20
862962007137	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-13
862962007138	HMMPfam hit to PF00593, TonB dependent receptor, score 5e-17
862962007139	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962007140	Signal peptide predicted for BF638R1721 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.670 between residues 29 and 30
862962007141	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962007142	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007143	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007144	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007145	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007146	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962007147	HMMPfam hit to PF00593, TonB dependent receptor, score 9e-15
862962007148	PS00018 EF-hand calcium-binding domain.
862962007149	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.5e-15
862962007150	Signal peptide predicted for BF638R1723 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 19 and 20
862962007151	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962007152	Signal peptide predicted for BF638R1724 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.950 between residues 21 and 22
862962007153	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007154	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007155	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007156	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962007157	HMMPfam hit to PF00593, TonB dependent receptor, score 4e-13
862962007158	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-15
862962007159	Signal peptide predicted for BF638R1725 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 19 and 20
862962007160	Signal peptide predicted for BF638R1726 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 36 and 37
862962007161	putative gene cluster for degradation of sialoglycoconjugates
862962007162	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007163	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007164	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007165	1 probable transmembrane helix predicted for BF638R1726 by TMHMM2.0 at aa 21-38
862962007166	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.2e-22
862962007167	HMMPfam hit to PF00593, TonB dependent receptor, score 2e-17
862962007168	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962007169	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962007170	SusD family; Region: SusD; pfam07980
862962007171	Signal peptide predicted for BF638R1727 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.837 between residues 21 and 22
862962007172	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007173	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
862962007174	catalytic site [active]
862962007175	BNR repeat-like domain; Region: BNR_2; pfam13088
862962007176	Asp-box motif; other site
862962007177	Signal peptide predicted for BF638R1728 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 22 and 23
862962007178	1 probable transmembrane helix predicted for BF638R1728 by TMHMM2.0 at aa 5-27
862962007179	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.029
862962007180	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.045
862962007181	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.024
862962007182	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2
862962007183	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.28
862962007184	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962007185	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962007186	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
862962007187	active site
862962007188	Signal peptide predicted for BF638R1729 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.976 between residues 23 and 24
862962007189	1 probable transmembrane helix predicted for BF638R1729 by TMHMM2.0 at aa 7-29
862962007190	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.0094
862962007191	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 1.6e-64
862962007192	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
862962007193	active site
862962007194	catalytic triad [active]
862962007195	oxyanion hole [active]
862962007196	Signal peptide predicted for BF638R1730 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.826 between residues 18 and 19
862962007197	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 5.3e-13
862962007198	sialate O-acetylesterase_like family of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like1; cd01827
862962007199	active site
862962007200	catalytic triad [active]
862962007201	oxyanion hole [active]
862962007202	Domain of unknown function (DUF303); Region: DUF303; pfam03629
862962007203	Signal peptide predicted for BF638R1731 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.718 between residues 19 and 20
862962007204	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 5.2e-11
862962007205	HMMPfam hit to PF03629, Domain of unknown function (DUF303), score 1.3e-66
862962007206	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
862962007207	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962007208	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962007209	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962007210	Signal peptide predicted for BF638R1732 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.795 between residues 18 and 19
862962007211	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 3.2e-05
862962007212	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 0.0022
862962007213	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 0.0013
862962007214	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962007215	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962007216	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962007217	active site
862962007218	Fn3 associated; Region: Fn3_assoc; pfam13287
862962007219	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962007220	sugar binding site [chemical binding]; other site
862962007221	Signal peptide predicted for BF638R1733 by SignalP 2.0 HMM (Signal peptide probability 0.810) with cleavage site probability 0.324 between residues 21 and 22
862962007222	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007223	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.0014
862962007224	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 6.8e-181
862962007225	HMMPfam hit to PF00754, F5/8 type C domain, score 1.3e-20
862962007226	cyclically-permuted mutarotase family protein; Region: mutarot_permut; TIGR03548
862962007227	Signal peptide predicted for BF638R1734 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.742 between residues 29 and 30
862962007228	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007229	HMMPfam hit to PF01344, Kelch motif, score 0.32
862962007230	HMMPfam hit to PF01344, Kelch motif, score 0.11
862962007231	HMMPfam hit to PF01344, Kelch motif, score 0.5
862962007232	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962007233	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962007234	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962007235	active site
862962007236	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962007237	Signal peptide predicted for BF638R1735 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.454 between residues 25 and 26
862962007238	1 probable transmembrane helix predicted for BF638R1735 by TMHMM2.0 at aa 12-34
862962007239	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 1.1e-05
862962007240	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 3.7e-176
862962007241	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962007242	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962007243	Signal peptide predicted for BF638R1736 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.988 between residues 22 and 23
862962007244	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007245	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962007246	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962007247	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962007248	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
862962007249	Signal peptide predicted for BF638R1737 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.723 between residues 21 and 22
862962007250	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 7.1e-59
862962007251	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 3.1e-07
862962007252	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 7.7e-10
862962007253	potential frameshift: common BLAST hit: gi|60681308|ref|YP_211452.1| outer membrane protein
862962007254	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007255	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007256	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962007257	Signal peptide predicted for BF638R1738 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 27 and 28
862962007258	1 probable transmembrane helix predicted for BF638R1738 by TMHMM2.0 at aa 5-27
862962007259	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.9e-15
862962007260	HMMPfam hit to PF00593, TonB dependent receptor, score 0.0003
862962007261	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007262	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962007263	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962007264	SusD family; Region: SusD; pfam07980
862962007265	Signal peptide predicted for BF638R1740 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.542 between residues 20 and 21
862962007266	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007267	chaperone protein DnaJ; Provisional; Region: PRK14289
862962007268	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
862962007269	HSP70 interaction site [polypeptide binding]; other site
862962007270	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
862962007271	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
862962007272	dimer interface [polypeptide binding]; other site
862962007273	HMMPfam hit to PF01556, DnaJ C terminal region, score 6.5e-51
862962007274	HMMPfam hit to PF00684, DnaJ central domain (4 repeats), score 6.6e-29
862962007275	PS00637 CXXCXGXG dnaJ domain signature.
862962007276	PS00190 Cytochrome c family heme-binding site signature.
862962007277	HMMPfam hit to PF00226, DnaJ domain, score 7.7e-40
862962007278	PS00636 Nt-dnaJ domain signature.
862962007279	GrpE; Region: GrpE; pfam01025
862962007280	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
862962007281	dimer interface [polypeptide binding]; other site
862962007282	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
862962007283	HMMPfam hit to PF01025, GrpE, score 8.1e-50
862962007284	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
862962007285	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962007286	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962007287	ABC transporter; Region: ABC_tran_2; pfam12848
862962007288	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962007289	HMMPfam hit to PF00005, ABC transporter, score 7.8e-40
862962007290	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007291	HMMPfam hit to PF00005, ABC transporter, score 7.8e-08
862962007292	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962007293	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962007294	HMMPfam hit to PF04542, Sigma-70 region, score 5.1e-20
862962007295	1 probable transmembrane helix predicted for BF638R1745 by TMHMM2.0 at aa 51-73
862962007296	Signal peptide predicted for BF638R1746 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.364 between residues 23 and 24
862962007297	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007298	1 probable transmembrane helix predicted for BF638R1746 by TMHMM2.0 at aa 335-354
862962007299	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962007300	Signal peptide predicted for BF638R1747 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.817 between residues 21 and 22
862962007301	7 probable transmembrane helices predicted for BF638R1748 by TMHMM2.0 at aa 15-37, 50-72, 94-116, 123-142, 157-179, 184-206 and 257-279
862962007302	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 9.7e-17
862962007303	Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins; Region: PI-PLCc_BcPLC_like; cd08586
862962007304	active site
862962007305	catalytic site [active]
862962007306	putative metal binding site [ion binding]; other site
862962007307	Signal peptide predicted for BF638R1749 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.990 between residues 25 and 26
862962007308	1 probable transmembrane helix predicted for BF638R1749 by TMHMM2.0 at aa 5-24
862962007309	HMMPfam hit to PF00388, Phosphatidylinositol-specific phospholipase, score 4.2e-06
862962007310	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
862962007311	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
862962007312	nucleotide binding site [chemical binding]; other site
862962007313	HMMPfam hit to PF00480, ROK family, score 6.7e-29
862962007314	1 probable transmembrane helix predicted for BF638R1750 by TMHMM2.0 at aa 212-234
862962007315	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962007316	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007317	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007318	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962007319	Signal peptide predicted for BF638R1751 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 27 and 28
862962007320	1 probable transmembrane helix predicted for BF638R1751 by TMHMM2.0 at aa 5-27
862962007321	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2e-13
862962007322	HMMPfam hit to PF00593, TonB dependent receptor, score 2.1e-19
862962007323	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962007324	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962007325	SusD family; Region: SusD; pfam07980
862962007326	Signal peptide predicted for BF638R1752 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.860 between residues 24 and 25
862962007327	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007328	Signal peptide predicted for BF638R1753 by SignalP 2.0 HMM (Signal peptide probability 0.922) with cleavage site probability 0.372 between residues 22 and 23
862962007329	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962007330	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962007331	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
862962007332	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
862962007333	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007334	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962007335	HMMPfam hit to PF07691, PA14 domain, score 1.8e-09
862962007336	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
862962007337	putative catalytic site [active]
862962007338	putative metal binding site [ion binding]; other site
862962007339	putative phosphate binding site [ion binding]; other site
862962007340	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2e-19
862962007341	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
862962007342	dimer interface [polypeptide binding]; other site
862962007343	Alkaline phosphatase homologues; Region: alkPPc; smart00098
862962007344	active site
862962007345	Signal peptide predicted for BF638R1755 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.992 between residues 27 and 28
862962007346	1 probable transmembrane helix predicted for BF638R1755 by TMHMM2.0 at aa 7-26
862962007347	HMMPfam hit to PF00245, Alkaline phosphatase, score 1.2e-36
862962007348	PS00123 Alkaline phosphatase active site.
862962007349	Trehalase; Region: Trehalase; cl17346
862962007350	Signal peptide predicted for BF638R1756 by SignalP 2.0 HMM (Signal peptide probability 0.952) with cleavage site probability 0.601 between residues 23 and 24
862962007351	Uncharacterized conserved protein [Function unknown]; Region: COG3538
862962007352	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
862962007353	Signal peptide predicted for BF638R1757 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.895 between residues 32 and 33
862962007354	HMMPfam hit to PF06824, Protein of unknown function (DUF1237), score 1.8e-248
862962007355	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962007356	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
862962007357	putative active site [active]
862962007358	putative metal binding site [ion binding]; other site
862962007359	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962007360	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
862962007361	Signal peptide predicted for BF638R1758 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 21 and 22
862962007362	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007363	1 probable transmembrane helix predicted for BF638R1758 by TMHMM2.0 at aa 5-27
862962007364	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4e-13
862962007365	HMMPfam hit to PF07691, PA14 domain, score 2.9e-07
862962007366	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
862962007367	putative dimerization interface [polypeptide binding]; other site
862962007368	Transcriptional regulators [Transcription]; Region: PurR; COG1609
862962007369	putative ligand binding site [chemical binding]; other site
862962007370	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962007371	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962007372	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 9.4e-06
862962007373	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6e-07
862962007374	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.027
862962007375	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007376	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962007377	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
862962007378	1 probable transmembrane helix predicted for BF638R1761 by TMHMM2.0 at aa 65-87
862962007379	Signal peptide predicted for BF638R1761 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.891 between residues 26 and 27
862962007380	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007381	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962007382	binding surface
862962007383	TPR motif; other site
862962007384	1 probable transmembrane helix predicted for BF638R1762 by TMHMM2.0 at aa 7-24
862962007385	Signal peptide predicted for BF638R1762 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.926 between residues 22 and 23
862962007386	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962007387	1 probable transmembrane helix predicted for BF638R1763 by TMHMM2.0 at aa 22-44
862962007388	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962007389	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
862962007390	DNA binding residues [nucleotide binding]
862962007391	4 probable transmembrane helices predicted for BF638R1764 by TMHMM2.0 at aa 35-57, 61-83, 140-162 and 167-189
862962007392	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007393	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962007394	Int/Topo IB signature motif; other site
862962007395	HMMPfam hit to PF00589, Phage integrase family, score 9.3e-08
862962007396	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
862962007397	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962007398	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962007399	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962007400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
862962007401	Signal peptide predicted for BF638R1771 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.921 between residues 19 and 20
862962007402	HMMPfam hit to PF07661, MORN repeat variant, score 18
862962007403	HMMPfam hit to PF07661, MORN repeat variant, score 31
862962007404	HMMPfam hit to PF07661, MORN repeat variant, score 0.29
862962007405	HMMPfam hit to PF07661, MORN repeat variant, score 18
862962007406	HMMPfam hit to PF07661, MORN repeat variant, score 21
862962007407	HMMPfam hit to PF07661, MORN repeat variant, score 0.051
862962007408	HMMPfam hit to PF07661, MORN repeat variant, score 0.2
862962007409	HMMPfam hit to PF07661, MORN repeat variant, score 2.6
862962007410	HMMPfam hit to PF07661, MORN repeat variant, score 0.94
862962007411	HMMPfam hit to PF07661, MORN repeat variant, score 1.8
862962007412	Signal peptide predicted for BF638R1772 by SignalP 2.0 HMM (Signal peptide probability 0.859) with cleavage site probability 0.452 between residues 59 and 60
862962007413	4 probable transmembrane helices predicted for BF638R1772 by TMHMM2.0 at aa 38-60, 70-89, 141-163 and 178-200
862962007414	4 probable transmembrane helices predicted for BF638R1773 by TMHMM2.0 at aa 22-44, 70-92, 134-156 and 166-188
862962007415	Signal peptide predicted for BF638R1774 by SignalP 2.0 HMM (Signal peptide probability 0.935) with cleavage site probability 0.748 between residues 26 and 27
862962007416	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007417	Signal peptide predicted for BF638R1775 by SignalP 2.0 HMM (Signal peptide probability 0.857) with cleavage site probability 0.631 between residues 22 and 23
862962007418	1 probable transmembrane helix predicted for BF638R1775 by TMHMM2.0 at aa 7-29
862962007419	Signal peptide predicted for BF638R1777 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.381 between residues 24 and 25
862962007420	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007421	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
862962007422	Signal peptide predicted for BF638R1779 by SignalP 2.0 HMM (Signal peptide probability 0.911) with cleavage site probability 0.635 between residues 26 and 27
862962007423	1 probable transmembrane helix predicted for BF638R1779 by TMHMM2.0 at aa 7-26
862962007424	Signal peptide predicted for BF638R1780 by SignalP 2.0 HMM (Signal peptide probability 0.974) with cleavage site probability 0.340 between residues 38 and 39
862962007425	1 probable transmembrane helix predicted for BF638R1780 by TMHMM2.0 at aa 7-29
862962007426	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007427	Signal peptide predicted for BF638R1781 by SignalP 2.0 HMM (Signal peptide probability 0.831) with cleavage site probability 0.649 between residues 30 and 31
862962007428	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007429	2 probable transmembrane helices predicted for BF638R1783 by TMHMM2.0 at aa 47-66 and 76-98
862962007430	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007431	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962007432	active site
862962007433	Int/Topo IB signature motif; other site
862962007434	DNA binding site [nucleotide binding]
862962007435	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962007436	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962007437	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007438	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962007439	active site
862962007440	Int/Topo IB signature motif; other site
862962007441	1 probable transmembrane helix predicted for BF638R1788 by TMHMM2.0 at aa 13-35
862962007442	Signal peptide predicted for BF638R1789 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.808 between residues 25 and 26
862962007443	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007444	Signal peptide predicted for BF638R1790 by SignalP 2.0 HMM (Signal peptide probability 0.606) with cleavage site probability 0.580 between residues 20 and 21
862962007445	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007446	PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
862962007447	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
862962007448	Receptor L domain; Region: Recep_L_domain; pfam01030
862962007449	Signal peptide predicted for BF638R1791 by SignalP 2.0 HMM (Signal peptide probability 0.770) with cleavage site probability 0.488 between residues 17 and 18
862962007450	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007451	Uncharacterized conserved protein [Function unknown]; Region: COG3391
862962007452	Signal peptide predicted for BF638R1792 by SignalP 2.0 HMM (Signal peptide probability 0.839) with cleavage site probability 0.581 between residues 34 and 35
862962007453	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007454	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
862962007455	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962007456	Signal peptide predicted for BF638R1793 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.502 between residues 19 and 20
862962007457	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.3e-15
862962007458	HMMPfam hit to PF00593, TonB dependent receptor, score 2.4e-25
862962007459	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
862962007460	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
862962007461	putative ligand binding site [chemical binding]; other site
862962007462	Signal peptide predicted for BF638R1794 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.716 between residues 22 and 23
862962007463	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007464	HMMPfam hit to PF01497, Periplasmic binding protein, score 3e-05
862962007465	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
862962007466	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
862962007467	ABC-ATPase subunit  interface; other site
862962007468	dimer interface [polypeptide binding]; other site
862962007469	putative PBP binding regions; other site
862962007470	Signal peptide predicted for BF638R1795 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.549 between residues 28 and 29
862962007471	8 probable transmembrane helices predicted for BF638R1795 by TMHMM2.0 at aa 7-29, 53-75, 88-110, 114-136, 143-165, 185-207, 234-256 and 297-319
862962007472	HMMPfam hit to PF01032, FecCD transport family, score 6.2e-69
862962007473	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
862962007474	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
862962007475	Walker A/P-loop; other site
862962007476	ATP binding site [chemical binding]; other site
862962007477	Q-loop/lid; other site
862962007478	ABC transporter signature motif; other site
862962007479	Walker B; other site
862962007480	D-loop; other site
862962007481	H-loop/switch region; other site
862962007482	HMMPfam hit to PF00005, ABC transporter, score 7.8e-40
862962007483	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007484	Predicted metal-binding protein (DUF2284); Region: DUF2284; pfam10050
862962007485	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962007486	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962007487	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
862962007488	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962007489	P-loop; other site
862962007490	Magnesium ion binding site [ion binding]; other site
862962007491	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 2.7e-12
862962007492	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007493	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962007494	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
862962007495	Toprim-like; Region: Toprim_2; pfam13155
862962007496	Signal peptide predicted for BF638R1802 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.995 between residues 49 and 50
862962007497	2 probable transmembrane helices predicted for BF638R1802 by TMHMM2.0 at aa 4-26 and 33-55
862962007498	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007499	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962007500	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962007501	2 probable transmembrane helices predicted for BF638R1803 by TMHMM2.0 at aa 10-32 and 45-66
862962007502	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.5e-14
862962007503	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007504	HMMPfam hit to PF00593, TonB dependent receptor, score 2.2e-21
862962007505	Signal peptide predicted for BF638R1804 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.553 between residues 26 and 27
862962007506	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007507	Signal peptide predicted for BF638R1805 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.349 between residues 29 and 30
862962007508	1 probable transmembrane helix predicted for BF638R1805 by TMHMM2.0 at aa 13-35
862962007509	Similar to BT
862962007510	Anticodon binding domain of tRNAs; Region: HGTP_anticodon2; pfam12745
862962007511	Signal peptide predicted for BF638R1806 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.759 between residues 19 and 20
862962007512	HEAT repeats; Region: HEAT_2; pfam13646
862962007513	Signal peptide predicted for BF638R1807 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.716 between residues 20 and 21
862962007514	Signal peptide predicted for BF638R1808 by SignalP 2.0 HMM (Signal peptide probability 0.912) with cleavage site probability 0.675 between residues 18 and 19
862962007515	Transposase, Mutator family; Region: Transposase_mut; pfam00872
862962007516	1 probable transmembrane helix predicted for BF638R1809 by TMHMM2.0 at aa 67-89
862962007517	Transposase domain (DUF772); Region: DUF772; pfam05598
862962007518	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
862962007519	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
862962007520	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
862962007521	PS00092 N-6 Adenine-specific DNA methylases signature.
862962007522	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962007523	Int/Topo IB signature motif; other site
862962007524	HMMPfam hit to PF00589, Phage integrase family, score 4e-07
862962007525	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962007526	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
862962007527	Int/Topo IB signature motif; other site
862962007528	HMMPfam hit to PF00589, Phage integrase family, score 2.7e-09
862962007529	Signal peptide predicted for BF638R1816 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.950 between residues 58 and 59
862962007530	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962007531	1 probable transmembrane helix predicted for BF638R1816 by TMHMM2.0 at aa 40-57
862962007532	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
862962007533	OmpA family; Region: OmpA; pfam00691
862962007534	ligand binding site [chemical binding]; other site
862962007535	Signal peptide predicted for BF638R1817 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.996 between residues 21 and 22
862962007536	Clostripain family; Region: Peptidase_C11; pfam03415
862962007537	Signal peptide predicted for BF638R1818 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.907 between residues 21 and 22
862962007538	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007539	Signal peptide predicted for BF638R1820 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.608 between residues 21 and 22
862962007540	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007541	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962007542	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
862962007543	Signal peptide predicted for BF638R1822 by SignalP 2.0 HMM (Signal peptide probability 0.693) with cleavage site probability 0.560 between residues 28 and 29
862962007544	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007545	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007546	PS00681 Chaperonins cpn10 signature.
862962007547	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007548	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007549	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007550	Signal peptide predicted for BF638R1825 by SignalP 2.0 HMM (Signal peptide probability 0.810) with cleavage site probability 0.589 between residues 30 and 31
862962007551	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007552	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007553	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007554	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007555	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007556	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007557	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007558	Signal peptide predicted for BF638R1826 by SignalP 2.0 HMM (Signal peptide probability 0.783) with cleavage site probability 0.570 between residues 25 and 26
862962007559	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007560	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007561	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007562	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007563	Signal peptide predicted for BF638R1827 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.790 between residues 33 and 34
862962007564	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007565	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007566	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cd13119
862962007567	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cd13119
862962007568	Signal peptide predicted for BF638R1828 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.537 between residues 19 and 20
862962007569	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007570	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007571	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007572	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007573	Signal peptide predicted for BF638R1830 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.485 between residues 42 and 43
862962007574	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007575	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007576	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007577	1 probable transmembrane helix predicted for BF638R1830 by TMHMM2.0 at aa 20-42
862962007578	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007579	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007580	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007581	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cd13119
862962007582	Signal peptide predicted for BF638R1831 by SignalP 2.0 HMM (Signal peptide probability 0.951) with cleavage site probability 0.464 between residues 19 and 20
862962007583	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007584	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007585	Signal peptide predicted for BF638R1832 by SignalP 2.0 HMM (Signal peptide probability 0.824) with cleavage site probability 0.406 between residues 33 and 34
862962007586	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007587	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007588	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007589	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007590	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007591	Signal peptide predicted for BF638R1834 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.699 between residues 22 and 23
862962007592	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007593	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007594	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cl17916
862962007595	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007596	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962007597	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962007598	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962007599	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962007600	Signal peptide predicted for BF638R1836 by SignalP 2.0 HMM (Signal peptide probability 0.826) with cleavage site probability 0.465 between residues 22 and 23
862962007601	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007602	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962007603	ligand binding site [chemical binding]; other site
862962007604	Signal peptide predicted for BF638R1837 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.717 between residues 20 and 21
862962007605	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
862962007606	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962007607	Signal peptide predicted for BF638R1840 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.515 between residues 33 and 34
862962007608	1 probable transmembrane helix predicted for BF638R1840 by TMHMM2.0 at aa 7-29
862962007609	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
862962007610	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
862962007611	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
862962007612	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
862962007613	RNA binding site [nucleotide binding]; other site
862962007614	HMMPfam hit to PF00575, S1 RNA binding domain, score 5.9e-23
862962007615	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962007616	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962007617	dimer interface [polypeptide binding]; other site
862962007618	phosphorylation site [posttranslational modification]
862962007619	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962007620	ATP binding site [chemical binding]; other site
862962007621	Mg2+ binding site [ion binding]; other site
862962007622	G-X-G motif; other site
862962007623	Signal peptide predicted for BF638R1842 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.985 between residues 28 and 29
862962007624	3 probable transmembrane helices predicted for BF638R1842 by TMHMM2.0 at aa 9-31, 277-299 and 369-391
862962007625	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007626	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.4e-25
862962007627	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.8e-31
862962007628	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
862962007629	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
862962007630	active site
862962007631	metal binding site [ion binding]; metal-binding site
862962007632	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
862962007633	Signal peptide predicted for BF638R1843 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.732 between residues 25 and 26
862962007634	1 probable transmembrane helix predicted for BF638R1843 by TMHMM2.0 at aa 7-24
862962007635	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.6e-16
862962007636	HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 1.6e-23
862962007637	PS00215 Mitochondrial energy transfer proteins signature.
862962007638	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
862962007639	GAF domain; Region: GAF_2; pfam13185
862962007640	HMMPfam hit to PF01590, GAF domain, score 8.3e-05
862962007641	Signal peptide predicted for BF638R1845 by SignalP 2.0 HMM (Signal peptide probability 0.954) with cleavage site probability 0.355 between residues 21 and 22
862962007642	1 probable transmembrane helix predicted for BF638R1845 by TMHMM2.0 at aa 7-29
862962007643	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007644	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
862962007645	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962007646	N-terminal plug; other site
862962007647	ligand-binding site [chemical binding]; other site
862962007648	Signal peptide predicted for BF638R1846 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 19 and 20
862962007649	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.9e-18
862962007650	HMMPfam hit to PF00593, TonB dependent receptor, score 9.5e-20
862962007651	Creatinine amidohydrolase; Region: Creatininase; pfam02633
862962007652	HMMPfam hit to PF02633, Creatinine amidohydrolase, score 4.9e-10
862962007653	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962007654	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962007655	ligand binding site [chemical binding]; other site
862962007656	flexible hinge region; other site
862962007657	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 9.3e-05
862962007658	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
862962007659	putative efflux protein, MATE family; Region: matE; TIGR00797
862962007660	12 probable transmembrane helices predicted for BF638R1849 by TMHMM2.0 at aa 19-41, 56-78, 99-121, 136-158, 171-193, 203-222, 243-265, 285-307, 327-349, 359-376, 396-418 and 422-444
862962007661	HMMPfam hit to PF01554, MatE, score 1.2e-19
862962007662	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007663	HMMPfam hit to PF01554, MatE, score 8.7e-19
862962007664	Signal peptide predicted for BF638R1850 by SignalP 2.0 HMM (Signal peptide probability 0.657) with cleavage site probability 0.342 between residues 23 and 24
862962007665	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962007666	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
862962007667	10 probable transmembrane helices predicted for BF638R1851 by TMHMM2.0 at aa 13-32, 47-69, 90-112, 132-154, 161-183, 193-215, 282-304, 324-346, 351-373 and 393-415
862962007668	HMMPfam hit to PF01554, MatE, score 1e-36
862962007669	HMMPfam hit to PF01554, MatE, score 1.8e-26
862962007670	putative transporter; Validated; Region: PRK03818
862962007671	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962007672	TrkA-C domain; Region: TrkA_C; pfam02080
862962007673	TrkA-C domain; Region: TrkA_C; pfam02080
862962007674	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
862962007675	11 probable transmembrane helices predicted for BF638R1852 by TMHMM2.0 at aa 13-30, 37-59, 69-91, 98-120, 157-179, 375-397, 402-424, 436-458, 468-490, 497-514 and 529-551
862962007676	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 7.2e-63
862962007677	HMMPfam hit to PF02080, TrkA-C domain, score 2e-10
862962007678	HMMPfam hit to PF02080, TrkA-C domain, score 6.8e-16
862962007679	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 1.3e-63
862962007680	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
862962007681	HMMPfam hit to PF06874, Firmicute fructose-1,6-bisphosphatase, score 0
862962007682	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
862962007683	Signal peptide predicted for BF638R1854 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.978 between residues 21 and 22
862962007684	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
862962007685	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962007686	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
862962007687	acyl-activating enzyme (AAE) consensus motif; other site
862962007688	putative AMP binding site [chemical binding]; other site
862962007689	putative active site [active]
862962007690	putative CoA binding site [chemical binding]; other site
862962007691	HMMPfam hit to PF00501, AMP-binding enzyme, score 9.8e-81
862962007692	PS00455 Putative AMP-binding domain signature.
862962007693	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
862962007694	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
862962007695	NADP binding site [chemical binding]; other site
862962007696	active site
862962007697	putative substrate binding site [chemical binding]; other site
862962007698	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
862962007699	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
862962007700	NADP-binding site; other site
862962007701	homotetramer interface [polypeptide binding]; other site
862962007702	substrate binding site [chemical binding]; other site
862962007703	homodimer interface [polypeptide binding]; other site
862962007704	active site
862962007705	PS00061 Short-chain dehydrogenases/reductases family signature.
862962007706	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
862962007707	AAA domain; Region: AAA_14; pfam13173
862962007708	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
862962007709	similar to PS_4/PS_B capsular polysaccharide biosynthesis locus in BF9343
862962007710	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962007711	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962007712	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 4e-81
862962007713	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962007714	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962007715	substrate binding site; other site
862962007716	tetramer interface; other site
862962007717	HMMPfam hit to PF00483, Nucleotidyl transferase, score 6.1e-106
862962007718	Signal peptide predicted for BF638R1865 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.454 between residues 45 and 46
862962007719	12 probable transmembrane helices predicted for BF638R1865 by TMHMM2.0 at aa 21-43, 66-88, 95-117, 121-143, 150-172, 182-204, 235-252, 274-296, 303-325, 330-352, 364-386 and 401-423
862962007720	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962007721	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
862962007722	active site
862962007723	metal-binding site
862962007724	cytidylyltransferase; Region: cytidylyltransferase; cd02170
862962007725	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
862962007726	active site
862962007727	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
862962007728	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
862962007729	tetramer interface [polypeptide binding]; other site
862962007730	active site
862962007731	Mg2+/Mn2+ binding site [ion binding]; other site
862962007732	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
862962007733	phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297
862962007734	PYR/PP interface [polypeptide binding]; other site
862962007735	dimer interface [polypeptide binding]; other site
862962007736	TPP binding site [chemical binding]; other site
862962007737	Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371
862962007738	TPP-binding site; other site
862962007739	PS00187 Thiamine pyrophosphate enzymes signature.
862962007740	2-aminoethylphosphonate aminotransferase; Region: PhnW-AepZ; TIGR03301
862962007741	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962007742	catalytic residue [active]
862962007743	HMMPfam hit to PF00266, Aminotransferase class-V, score 4e-09
862962007744	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962007745	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
862962007746	inhibitor-cofactor binding pocket; inhibition site
862962007747	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962007748	catalytic residue [active]
862962007749	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 7.8e-90
862962007750	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007751	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
862962007752	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
862962007753	trimer interface [polypeptide binding]; other site
862962007754	active site
862962007755	substrate binding site [chemical binding]; other site
862962007756	CoA binding site [chemical binding]; other site
862962007757	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.43
862962007758	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 9.5
862962007759	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 25
862962007760	PS00101 Hexapeptide-repeat containing-transferases signature.
862962007761	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1
862962007762	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962007763	active site
862962007764	HMMPfam hit to PF00535, Glycosyl transferase, score 1.5e-15
862962007765	Sulfatase; Region: Sulfatase; cl17466
862962007766	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962007767	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962007768	12 probable transmembrane helices predicted for BF638R1874 by TMHMM2.0 at aa 5-26, 41-63, 76-98, 113-135, 140-162, 166-188, 213-235, 250-272, 293-315, 325-347, 360-382 and 386-408
862962007769	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007770	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
862962007771	GDP-Fucose binding site [chemical binding]; other site
862962007772	HMMPfam hit to PF01531, Glycosyl transferase family, score 1e-08
862962007773	11 probable transmembrane helices predicted for BF638R1876 by TMHMM2.0 at aa 4-25, 45-67, 82-104, 125-147, 152-174, 181-201, 205-220, 227-249, 362-384, 391-408 and 418-440
862962007774	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007775	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962007776	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962007777	HMMPfam hit to PF00534, Glycosyl transferases group, score 0.00016
862962007778	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
862962007779	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
862962007780	NAD(P) binding site [chemical binding]; other site
862962007781	homodimer interface [polypeptide binding]; other site
862962007782	substrate binding site [chemical binding]; other site
862962007783	active site
862962007784	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
862962007785	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 8.4e-11
862962007786	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962007787	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962007788	active site
862962007789	homodimer interface [polypeptide binding]; other site
862962007790	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1e-135
862962007791	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
862962007792	NADP binding site [chemical binding]; other site
862962007793	active site
862962007794	putative substrate binding site [chemical binding]; other site
862962007795	putative glycosyl transferase; Provisional; Region: PRK10307
862962007796	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
862962007797	2 probable transmembrane helices predicted for BF638R1881 by TMHMM2.0 at aa 75-97 and 104-121
862962007798	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007799	HMMPfam hit to PF00534, Glycosyl transferases group, score 8.3e-14
862962007800	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962007801	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962007802	NAD(P) binding site [chemical binding]; other site
862962007803	active site
862962007804	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
862962007805	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
862962007806	Mg++ binding site [ion binding]; other site
862962007807	putative catalytic motif [active]
862962007808	putative substrate binding site [chemical binding]; other site
862962007809	11 probable transmembrane helices predicted for BF638R1883 by TMHMM2.0 at aa 4-21, 41-58, 62-79, 91-108, 112-131, 138-160, 164-181, 188-210, 215-237, 258-280 and 290-312
862962007810	HMMPfam hit to PF00953, Glycosyl transferase, score 2.7e-08
862962007811	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962007812	sequence-specific DNA binding site [nucleotide binding]; other site
862962007813	salt bridge; other site
862962007814	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962007815	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
862962007816	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
862962007817	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 7.5e-09
862962007818	10 probable transmembrane helices predicted for BF638R1887 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 128-150, 163-185, 195-217, 238-258, 273-295, 307-329 and 349-371
862962007819	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
862962007820	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
862962007821	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
862962007822	HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 3.3e-105
862962007823	HMMPfam hit to PF00393, 6-phosphogluconate dehydrogenase, C-ter, score 2.4e-146
862962007824	PS00461 6-phosphogluconate dehydrogenase signature.
862962007825	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
862962007826	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
862962007827	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
862962007828	HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, NAD bindi, score 6e-66
862962007829	HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, C-termina, score 8.7e-154
862962007830	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
862962007831	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
862962007832	putative active site [active]
862962007833	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 0.0012
862962007834	Signal peptide predicted for BF638R1892 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.870 between residues 45 and 46
862962007835	1 probable transmembrane helix predicted for BF638R1892 by TMHMM2.0 at aa 21-43
862962007836	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
862962007837	putative ligand binding site [chemical binding]; other site
862962007838	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
862962007839	Signal peptide predicted for BF638R1893 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.990 between residues 27 and 28
862962007840	1 probable transmembrane helix predicted for BF638R1893 by TMHMM2.0 at aa 7-29
862962007841	Urea transporter; Region: UT; pfam03253
862962007842	HMMPfam hit to PF03253, Urea transporter, score 3.9e-31
862962007843	8 probable transmembrane helices predicted for BF638R1894 by TMHMM2.0 at aa 21-43, 72-94, 114-136, 159-181, 186-205, 210-229, 234-253 and 257-279
862962007844	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007845	Signal peptide predicted for BF638R1895 by SignalP 2.0 HMM (Signal peptide probability 0.769) with cleavage site probability 0.629 between residues 27 and 28
862962007846	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007847	PS00334 Myb DNA-binding domain repeat signature 2.
862962007848	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962007849	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
862962007850	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
862962007851	active site
862962007852	DNA binding site [nucleotide binding]
862962007853	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
862962007854	HMMPfam hit to PF00817, impB/mucB/samB family, score 4.3e-87
862962007855	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
862962007856	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
862962007857	Catalytic site [active]
862962007858	HMMPfam hit to PF00717, Peptidase S24-like, score 1.3e-17
862962007859	Signal peptide predicted for BF638R1899 by SignalP 2.0 HMM (Signal peptide probability 0.907) with cleavage site probability 0.533 between residues 27 and 28
862962007860	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007861	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
862962007862	putative active site; other site
862962007863	putative metal binding residues [ion binding]; other site
862962007864	Signal peptide predicted for BF638R1900 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.923 between residues 25 and 26
862962007865	1 probable transmembrane helix predicted for BF638R1900 by TMHMM2.0 at aa 7-26
862962007866	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007867	two-component response regulator; Provisional; Region: PRK14084
862962007868	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962007869	active site
862962007870	phosphorylation site [posttranslational modification]
862962007871	intermolecular recognition site; other site
862962007872	dimerization interface [polypeptide binding]; other site
862962007873	LytTr DNA-binding domain; Region: LytTR; smart00850
862962007874	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 1.1e-22
862962007875	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.6e-21
862962007876	Histidine kinase; Region: His_kinase; pfam06580
862962007877	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
862962007878	ATP binding site [chemical binding]; other site
862962007879	Mg2+ binding site [ion binding]; other site
862962007880	G-X-G motif; other site
862962007881	HMMPfam hit to PF06580, Histidine kinase, score 7.7e-35
862962007882	4 probable transmembrane helices predicted for BF638R1903 by TMHMM2.0 at aa 12-34, 49-71, 78-97 and 117-139
862962007883	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962007884	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962007885	FtsX-like permease family; Region: FtsX; pfam02687
862962007886	HMMPfam hit to PF02687, Predicted permease, score 6.6e-47
862962007887	4 probable transmembrane helices predicted for BF638R1904 by TMHMM2.0 at aa 21-43, 280-302, 335-357 and 367-389
862962007888	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007889	Signal peptide predicted for BF638R1904 by SignalP 2.0 HMM (Signal peptide probability 0.935) with cleavage site probability 0.489 between residues 42 and 43
862962007890	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962007891	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962007892	Walker A/P-loop; other site
862962007893	ATP binding site [chemical binding]; other site
862962007894	Q-loop/lid; other site
862962007895	ABC transporter signature motif; other site
862962007896	Walker B; other site
862962007897	D-loop; other site
862962007898	H-loop/switch region; other site
862962007899	HMMPfam hit to PF00005, ABC transporter, score 2.8e-57
862962007900	PS00211 ABC transporters family signature.
862962007901	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007902	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962007903	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
862962007904	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962007905	HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00021
862962007906	1 probable transmembrane helix predicted for BF638R1906 by TMHMM2.0 at aa 7-29
862962007907	Signal peptide predicted for BF638R1906 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.230 between residues 23 and 24
862962007908	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962007909	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.3e-29
862962007910	HMMPfam hit to PF02321, Outer membrane efflux protein, score 4e-12
862962007911	Signal peptide predicted for BF638R1907 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.975 between residues 25 and 26
862962007912	1 probable transmembrane helix predicted for BF638R1908 by TMHMM2.0 at aa 34-53
862962007913	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
862962007914	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
862962007915	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
862962007916	HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 1.6e-169
862962007917	9 probable transmembrane helices predicted for BF638R1909 by TMHMM2.0 at aa 15-37, 64-86, 101-123, 130-152, 191-213, 220-242, 401-423, 436-455 and 484-506
862962007918	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007919	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
862962007920	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
862962007921	Signal peptide predicted for BF638R1910 by SignalP 2.0 HMM (Signal peptide probability 0.619) with cleavage site probability 0.532 between residues 30 and 31
862962007922	HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 1.9e-11
862962007923	9 probable transmembrane helices predicted for BF638R1910 by TMHMM2.0 at aa 13-35, 56-78, 82-101, 121-143, 180-202, 214-236, 259-281, 293-312 and 343-365
862962007924	WGR domain; Region: WGR; cd07994
862962007925	HMMPfam hit to PF05406, WGR domain, score 5.7e-15
862962007926	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
862962007927	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962007928	Sulfatase; Region: Sulfatase; cl17466
862962007929	coproporphyrinogen III oxidase; Validated; Region: PRK08208
862962007930	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962007931	FeS/SAM binding site; other site
862962007932	HemN C-terminal domain; Region: HemN_C; pfam06969
862962007933	HMMPfam hit to PF04055, Radical SAM superfamily, score 4.6e-22
862962007934	HMMPfam hit to PF06969, HemN C-terminal region, score 3.8e-06
862962007935	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962007936	FeS/SAM binding site; other site
862962007937	phosphoglycolate phosphatase; Provisional; Region: PRK01158
862962007938	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
862962007939	active site
862962007940	motif I; other site
862962007941	motif II; other site
862962007942	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
862962007943	HMMPfam hit to PF04055, Radical SAM superfamily, score 0.015
862962007944	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007945	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.4e-06
862962007946	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007947	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
862962007948	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
862962007949	putative ligand binding site [chemical binding]; other site
862962007950	putative NAD binding site [chemical binding]; other site
862962007951	catalytic site [active]
862962007952	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 6.9e-44
862962007953	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
862962007954	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
862962007955	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.4e-19
862962007956	recombination factor protein RarA; Reviewed; Region: PRK13342
862962007957	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962007958	Walker A motif; other site
862962007959	ATP binding site [chemical binding]; other site
862962007960	Walker B motif; other site
862962007961	arginine finger; other site
862962007962	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
862962007963	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.9e-17
862962007964	PS00017 ATP/GTP-binding site motif A (P-loop).
862962007965	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962007966	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962007967	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962007968	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
862962007969	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962007970	sugar binding site [chemical binding]; other site
862962007971	HMMPfam hit to PF00754, F5/8 type C domain, score 1.3e-12
862962007972	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 2.8e-12
862962007973	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962007974	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 3.6e-05
862962007975	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 6.4e-42
862962007976	Signal peptide predicted for BF638R1918 by SignalP 2.0 HMM (Signal peptide probability 0.958) with cleavage site probability 0.639 between residues 29 and 30
862962007977	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962007978	Signal peptide predicted for BF638R1919 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 25 and 26
862962007979	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962007980	active site
862962007981	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
862962007982	homodimer interface [polypeptide binding]; other site
862962007983	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 6.1e-42
862962007984	Predicted membrane protein [Function unknown]; Region: COG2860
862962007985	UPF0126 domain; Region: UPF0126; pfam03458
862962007986	UPF0126 domain; Region: UPF0126; pfam03458
862962007987	7 probable transmembrane helices predicted for BF638R1921 by TMHMM2.0 at aa 10-32, 37-59, 63-85, 90-112, 122-144, 149-168 and 178-196
862962007988	HMMPfam hit to PF03458, UPF0126 domain, score 2e-25
862962007989	HMMPfam hit to PF03458, UPF0126 domain, score 2.1e-22
862962007990	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
862962007991	Signal peptide predicted for BF638R1922 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.831 between residues 24 and 25
862962007992	1 probable transmembrane helix predicted for BF638R1922 by TMHMM2.0 at aa 7-24
862962007993	1 probable transmembrane helix predicted for BF638R1923 by TMHMM2.0 at aa 62-80
862962007994	Peptidase family M48; Region: Peptidase_M48; cl12018
862962007995	HMMPfam hit to PF01435, Peptidase family M48, score 7.9e-19
862962007996	4 probable transmembrane helices predicted for BF638R1924 by TMHMM2.0 at aa 20-42, 62-84, 177-199 and 214-236
862962007997	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
862962007998	HMMPfam hit to PF04011, LemA family, score 3.6e-63
862962007999	1 probable transmembrane helix predicted for BF638R1925 by TMHMM2.0 at aa 4-25
862962008000	Signal peptide predicted for BF638R1925 by SignalP 2.0 HMM (Signal peptide probability 0.620) with cleavage site probability 0.336 between residues 23 and 24
862962008001	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962008002	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962008003	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962008004	DNA binding residues [nucleotide binding]
862962008005	HMMPfam hit to PF04542, Sigma-70 region, score 9.3e-12
862962008006	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
862962008007	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
862962008008	active site
862962008009	catalytic residues [active]
862962008010	metal binding site [ion binding]; metal-binding site
862962008011	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962008012	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008013	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962008014	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008015	Signal peptide predicted for BF638R1928 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 29 and 30
862962008016	1 probable transmembrane helix predicted for BF638R1928 by TMHMM2.0 at aa 7-29
862962008017	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6e-19
862962008018	HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-08
862962008019	Signal peptide predicted for BF638R1929 by SignalP 2.0 HMM (Signal peptide probability 0.908) with cleavage site probability 0.421 between residues 31 and 32
862962008020	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962008021	1 probable transmembrane helix predicted for BF638R1929 by TMHMM2.0 at aa 12-29
862962008022	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008023	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
862962008024	Transglycosylase; Region: Transgly; cl17702
862962008025	HMMPfam hit to PF00912, Transglycosylase, score 9.5e-69
862962008026	1 probable transmembrane helix predicted for BF638R1930 by TMHMM2.0 at aa 13-35
862962008027	Signal peptide predicted for BF638R1930 by SignalP 2.0 HMM (Signal peptide probability 0.896) with cleavage site probability 0.313 between residues 24 and 25
862962008028	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962008029	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962008030	ligand binding site [chemical binding]; other site
862962008031	HMMPfam hit to PF00691, OmpA family, score 3.2e-11
862962008032	2 probable transmembrane helices predicted for BF638R1931 by TMHMM2.0 at aa 30-49 and 54-73
862962008033	Signal peptide predicted for BF638R1931 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.472 between residues 24 and 25
862962008034	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008035	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962008036	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
862962008037	10 probable transmembrane helices predicted for BF638R1932 by TMHMM2.0 at aa 16-34, 49-71, 92-114, 138-160, 167-189, 193-215, 236-258, 315-337, 377-399 and 414-436
862962008038	HMMPfam hit to PF01554, MatE, score 5.8e-34
862962008039	Signal peptide predicted for BF638R1932 by SignalP 2.0 HMM (Signal peptide probability 0.732) with cleavage site probability 0.523 between residues 32 and 33
862962008040	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
862962008041	EamA-like transporter family; Region: EamA; pfam00892
862962008042	EamA-like transporter family; Region: EamA; pfam00892
862962008043	10 probable transmembrane helices predicted for BF638R1933 by TMHMM2.0 at aa 7-29, 42-64, 71-93, 97-119, 128-150, 155-174, 190-207, 217-239, 246-268 and 272-291
862962008044	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.7e-20
862962008045	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 9.5e-21
862962008046	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962008047	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008048	Signal peptide predicted for BF638R1934 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.810 between residues 26 and 27
862962008049	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962008050	FecR protein; Region: FecR; pfam04773
862962008051	HMMPfam hit to PF04773, FecR protein, score 9.3e-18
862962008052	1 probable transmembrane helix predicted for BF638R1935 by TMHMM2.0 at aa 41-63
862962008053	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962008054	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962008055	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962008056	DNA binding residues [nucleotide binding]
862962008057	HMMPfam hit to PF04542, Sigma-70 region, score 5.8e-05
862962008058	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008059	1 probable transmembrane helix predicted for BF638R1937 by TMHMM2.0 at aa 5-27
862962008060	Signal peptide predicted for BF638R1937 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.948 between residues 26 and 27
862962008061	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
862962008062	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
862962008063	1 probable transmembrane helix predicted for BF638R1941 by TMHMM2.0 at aa 55-72
862962008064	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962008065	PS00430 TonB-dependent receptor proteins signature 1.
862962008066	Signal peptide predicted for BF638R1942 by SignalP 2.0 HMM (Signal peptide probability 0.852) with cleavage site probability 0.749 between residues 27 and 28
862962008067	PS00430 TonB-dependent receptor proteins signature 1.
862962008068	flavodoxin; Provisional; Region: PRK07116
862962008069	Signal peptide predicted for BF638R1945 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.708 between residues 20 and 21
862962008070	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008071	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
862962008072	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
862962008073	HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 2.4e-26
862962008074	Signal peptide predicted for BF638R1946 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.975 between residues 19 and 20
862962008075	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
862962008076	trimer interface [polypeptide binding]; other site
862962008077	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
862962008078	active site
862962008079	substrate binding site [chemical binding]; other site
862962008080	CoA binding site [chemical binding]; other site
862962008081	PS00101 Hexapeptide-repeat containing-transferases signature.
862962008082	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.53
862962008083	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 4.4
862962008084	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.23
862962008085	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 9.4
862962008086	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962008087	PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; Region: PDZ_signaling; cd00992
862962008088	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
862962008089	Catalytic dyad [active]
862962008090	Signal peptide predicted for BF638R1948 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.523 between residues 24 and 25
862962008091	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008092	HMMPfam hit to PF03572, Peptidase family S41, score 2.6e-14
862962008093	1 probable transmembrane helix predicted for BF638R1949 by TMHMM2.0 at aa 38-60
862962008094	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008095	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
862962008096	protoporphyrinogen oxidase; Region: PLN02576
862962008097	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
862962008098	HMMPfam hit to PF01593, Flavin containing amine oxidoreductase, score 9.4e-06
862962008099	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
862962008100	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962008101	FeS/SAM binding site; other site
862962008102	HemN C-terminal domain; Region: HemN_C; pfam06969
862962008103	HMMPfam hit to PF06969, HemN C-terminal region, score 7.8e-21
862962008104	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.8e-21
862962008105	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962008106	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
862962008107	putative substrate translocation pore; other site
862962008108	12 probable transmembrane helices predicted for BF638R1954 by TMHMM2.0 at aa 22-44, 54-74, 87-105, 109-126, 147-169, 173-195, 229-251, 261-283, 292-314, 319-341, 354-376 and 381-403
862962008109	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.3e-29
862962008110	PS00107 Protein kinases ATP-binding region signature.
862962008111	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008112	Signal peptide predicted for BF638R1954 by SignalP 2.0 HMM (Signal peptide probability 0.973) with cleavage site probability 0.502 between residues 39 and 40
862962008113	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962008114	N-terminal plug; other site
862962008115	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
862962008116	ligand-binding site [chemical binding]; other site
862962008117	HMMPfam hit to PF00593, TonB dependent receptor, score 5.6e-22
862962008118	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.3e-18
862962008119	Signal peptide predicted for BF638R1955 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.980 between residues 17 and 18
862962008120	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008121	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962008122	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962008123	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962008124	ligand binding site [chemical binding]; other site
862962008125	Signal peptide predicted for BF638R1958 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 26 and 27
862962008126	HMMPfam hit to PF00691, OmpA family, score 3.3e-18
862962008127	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962008128	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962008129	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.22
862962008130	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.2e-05
862962008131	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
862962008132	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962008133	N-terminal plug; other site
862962008134	ligand-binding site [chemical binding]; other site
862962008135	Signal peptide predicted for BF638R1960 by SignalP 2.0 HMM (Signal peptide probability 0.945) with cleavage site probability 0.794 between residues 21 and 22
862962008136	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.4e-18
862962008137	HMMPfam hit to PF00593, TonB dependent receptor, score 4e-23
862962008138	PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site.
862962008139	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008140	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962008141	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962008142	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008143	Signal peptide predicted for BF638R1961 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.474 between residues 27 and 28
862962008144	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.8e-12
862962008145	HMMPfam hit to PF00593, TonB dependent receptor, score 4.6e-10
862962008146	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962008147	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962008148	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962008149	Signal peptide predicted for BF638R1962 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.560 between residues 29 and 30
862962008150	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008151	Signal peptide predicted for BF638R1963 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.159 between residues 44 and 45
862962008152	1 probable transmembrane helix predicted for BF638R1963 by TMHMM2.0 at aa 12-29
862962008153	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008154	Domain of unknown function (DUF4302); Region: DUF4302; pfam14135
862962008155	Signal peptide predicted for BF638R1965 by SignalP 2.0 HMM (Signal peptide probability 0.854) with cleavage site probability 0.748 between residues 31 and 32
862962008156	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008157	Signal peptide predicted for BF638R1966 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.609 between residues 22 and 23
862962008158	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008159	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008160	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
862962008161	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962008162	Interdomain contacts; other site
862962008163	Cytokine receptor motif; other site
862962008164	Signal peptide predicted for BF638R1967 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.737 between residues 23 and 24
862962008165	1 probable transmembrane helix predicted for BF638R1967 by TMHMM2.0 at aa 7-29
862962008166	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.00017
862962008167	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
862962008168	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
862962008169	SLBB domain; Region: SLBB; pfam10531
862962008170	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
862962008171	SLBB domain; Region: SLBB; pfam10531
862962008172	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
862962008173	SLBB domain; Region: SLBB; pfam10531
862962008174	HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 9.6e-10
862962008175	Signal peptide predicted for BF638R1971 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.792 between residues 22 and 23
862962008176	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008177	FOG: PKD repeat [General function prediction only]; Region: COG3291
862962008178	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
862962008179	PKD domain; Region: PKD; pfam00801
862962008180	HMMPfam hit to PF00801, PKD domain, score 8.4e-06
862962008181	Signal peptide predicted for BF638R1972 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.377 between residues 34 and 35
862962008182	1 probable transmembrane helix predicted for BF638R1972 by TMHMM2.0 at aa 10-27
862962008183	1 probable transmembrane helix predicted for BF638R1973 by TMHMM2.0 at aa 19-41
862962008184	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008185	Signal peptide predicted for BF638R1974 by SignalP 2.0 HMM (Signal peptide probability 0.740) with cleavage site probability 0.346 between residues 37 and 38
862962008186	1 probable transmembrane helix predicted for BF638R1974 by TMHMM2.0 at aa 13-35
862962008187	Protein of unknown function (DUF1305); Region: DUF1305; cl01404
862962008188	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
862962008189	5 probable transmembrane helices predicted for BF638R1977 by TMHMM2.0 at aa 10-29, 41-63, 68-90, 102-119 and 129-146
862962008190	4 probable transmembrane helices predicted for BF638R1978 by TMHMM2.0 at aa 39-61, 74-96, 142-164 and 179-201
862962008191	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008192	3 probable transmembrane helices predicted for BF638R1979 by TMHMM2.0 at aa 589-606, 647-669 and 695-717
862962008193	PAAR motif; Region: PAAR_motif; pfam05488
862962008194	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
862962008195	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
862962008196	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
862962008197	HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 5.3e-17
862962008198	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
862962008199	3 probable transmembrane helices predicted for BF638R1987 by TMHMM2.0 at aa 21-43, 63-85 and 105-127
862962008200	1 probable transmembrane helix predicted for BF638R1988 by TMHMM2.0 at aa 279-301
862962008201	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
862962008202	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962008203	Walker A motif; other site
862962008204	ATP binding site [chemical binding]; other site
862962008205	Walker B motif; other site
862962008206	arginine finger; other site
862962008207	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962008208	Walker A motif; other site
862962008209	ATP binding site [chemical binding]; other site
862962008210	Walker B motif; other site
862962008211	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
862962008212	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 3.2e-80
862962008213	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008214	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.5e-05
862962008215	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008216	Protein of unknown function (DUF877); Region: DUF877; pfam05943
862962008217	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962008218	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
862962008219	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
862962008220	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962008221	catalytic residue [active]
862962008222	HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.6e-20
862962008223	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962008224	Part of AAA domain; Region: AAA_19; pfam13245
862962008225	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
862962008226	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008227	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
862962008228	active site 1 [active]
862962008229	dimer interface [polypeptide binding]; other site
862962008230	hexamer interface [polypeptide binding]; other site
862962008231	active site 2 [active]
862962008232	HMMPfam hit to PF01361, Tautomerase enzyme, score 9.5e-09
862962008233	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962008234	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962008235	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.3e-10
862962008236	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962008237	DNA binding site [nucleotide binding]
862962008238	Conugative transposon
862962008239	Similar to Bacteroides fragilis YCH46
862962008240	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like d, score 0.0079
862962008241	1 probable transmembrane helix predicted for BF638R2007 by TMHMM2.0 at aa 75-97
862962008242	Signal peptide predicted for BF638R2008 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.493 between residues 20 and 21
862962008243	1 probable transmembrane helix predicted for BF638R2008 by TMHMM2.0 at aa 112-134
862962008244	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
862962008245	1 probable transmembrane helix predicted for BF638R2009 by TMHMM2.0 at aa 7-25
862962008246	1 probable transmembrane helix predicted for BF638R2010 by TMHMM2.0 at aa 50-72
862962008247	1 probable transmembrane helix predicted for BF638R2011 by TMHMM2.0 at aa 10-32
862962008249	HMMPfam hit to PF01609, Transposase DDE domain, score 0.024
862962008250	WYL domain; Region: WYL; pfam13280
862962008251	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
862962008252	DEAD-like helicases superfamily; Region: DEXDc; smart00487
862962008253	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962008254	ATP binding site [chemical binding]; other site
862962008255	ATP binding site [chemical binding]; other site
862962008256	putative Mg++ binding site [ion binding]; other site
862962008257	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962008258	nucleotide binding region [chemical binding]; other site
862962008259	ATP-binding site [chemical binding]; other site
862962008260	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
862962008261	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.2e-14
862962008262	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 9.6e-14
862962008263	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962008264	active site
862962008265	Int/Topo IB signature motif; other site
862962008266	DNA binding site [nucleotide binding]
862962008267	1 probable transmembrane helix predicted for BF638R2018 by TMHMM2.0 at aa 66-88
862962008268	PS00093 N-4 cytosine-specific DNA methylases signature.
862962008269	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
862962008270	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962008271	RteC protein; Region: RteC; pfam09357
862962008272	Isochorismatase family; Region: Isochorismatase; pfam00857
862962008273	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
862962008274	catalytic triad [active]
862962008275	conserved cis-peptide bond; other site
862962008276	HMMPfam hit to PF00857, Isochorismatase family, score 6.6e-09
862962008277	Predicted transcriptional regulators [Transcription]; Region: COG1733
862962008278	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
862962008279	HMMPfam hit to PF01638, Transcriptional regulator, score 1.1e-34
862962008280	Cupin domain; Region: Cupin_2; pfam07883
862962008281	HMMPfam hit to PF07883, Cupin domain, score 2.2e-05
862962008282	Signal peptide predicted for BF638R2029 by SignalP 2.0 HMM (Signal peptide probability 0.689) with cleavage site probability 0.650 between residues 27 and 28
862962008283	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962008284	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962008285	ligand binding site [chemical binding]; other site
862962008286	flexible hinge region; other site
862962008287	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962008288	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 9.4e-05
862962008289	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962008290	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962008291	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962008292	DNA binding site [nucleotide binding]
862962008293	active site
862962008294	Int/Topo IB signature motif; other site
862962008295	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962008296	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
862962008297	active site
862962008298	metal binding site [ion binding]; metal-binding site
862962008299	interdomain interaction site; other site
862962008300	AAA domain; Region: AAA_25; pfam13481
862962008301	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
862962008302	Walker A motif; other site
862962008303	ATP binding site [chemical binding]; other site
862962008304	Walker B motif; other site
862962008305	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008306	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962008307	Ion channel; Region: Ion_trans_2; pfam07885
862962008308	Signal peptide predicted for BF638R2037 by SignalP 2.0 HMM (Signal peptide probability 0.780) with cleavage site probability 0.381 between residues 26 and 27
862962008309	3 probable transmembrane helices predicted for BF638R2037 by TMHMM2.0 at aa 12-34, 49-68 and 75-97
862962008310	HMMPfam hit to PF07885, Ion channel, score 1.2e-17
862962008311	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
862962008312	AAA domain; Region: AAA_25; pfam13481
862962008313	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008314	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008315	PS00697 ATP-dependent DNA ligase AMP-binding site.
862962008316	1 probable transmembrane helix predicted for BF638R2043 by TMHMM2.0 at aa 5-27
862962008317	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962008318	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962008319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
862962008320	Signal peptide predicted for BF638R2045 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.902 between residues 19 and 20
862962008321	HMMPfam hit to PF07661, MORN repeat variant, score 4
862962008322	HMMPfam hit to PF07661, MORN repeat variant, score 46
862962008323	HMMPfam hit to PF07661, MORN repeat variant, score 0.29
862962008324	HMMPfam hit to PF07661, MORN repeat variant, score 18
862962008325	HMMPfam hit to PF07661, MORN repeat variant, score 15
862962008326	HMMPfam hit to PF07661, MORN repeat variant, score 0.051
862962008327	HMMPfam hit to PF07661, MORN repeat variant, score 0.2
862962008328	HMMPfam hit to PF07661, MORN repeat variant, score 16
862962008329	HMMPfam hit to PF07661, MORN repeat variant, score 3.5
862962008330	HMMPfam hit to PF07661, MORN repeat variant, score 1.8
862962008331	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
862962008332	Signal peptide predicted for BF638R2046 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.446 between residues 34 and 35
862962008333	1 probable transmembrane helix predicted for BF638R2046 by TMHMM2.0 at aa 13-35
862962008334	Signal peptide predicted for BF638R2048 by SignalP 2.0 HMM (Signal peptide probability 0.827) with cleavage site probability 0.655 between residues 51 and 52
862962008335	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008336	Signal peptide predicted for BF638R2049 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.718 between residues 28 and 29
862962008337	1 probable transmembrane helix predicted for BF638R2049 by TMHMM2.0 at aa 5-27
862962008338	Signal peptide predicted for BF638R2051 by SignalP 2.0 HMM (Signal peptide probability 0.923) with cleavage site probability 0.370 between residues 21 and 22
862962008339	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008340	2 probable transmembrane helices predicted for BF638R2052 by TMHMM2.0 at aa 31-53 and 95-117
862962008341	4 probable transmembrane helices predicted for BF638R2053 by TMHMM2.0 at aa 61-83, 93-115, 170-187 and 233-255
862962008342	4 probable transmembrane helices predicted for BF638R2054 by TMHMM2.0 at aa 35-57, 67-86, 142-164 and 174-193
862962008343	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008344	Signal peptide predicted for BF638R2055 by SignalP 2.0 HMM (Signal peptide probability 0.647) with cleavage site probability 0.474 between residues 59 and 60
862962008345	4 probable transmembrane helices predicted for BF638R2055 by TMHMM2.0 at aa 42-64, 68-90, 147-169 and 174-196
862962008346	Signal peptide predicted for BF638R2056 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.789 between residues 28 and 29
862962008347	1 probable transmembrane helix predicted for BF638R2056 by TMHMM2.0 at aa 5-27
862962008348	Predicted ATPase [General function prediction only]; Region: COG5293
862962008349	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
862962008350	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962008351	S-adenosylmethionine binding site [chemical binding]; other site
862962008352	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
862962008353	DEAD-like helicases superfamily; Region: DEXDc; smart00487
862962008354	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
862962008355	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
862962008356	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
862962008357	helicase superfamily c-terminal domain; Region: HELICc; smart00490
862962008358	ATP-binding site [chemical binding]; other site
862962008359	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.00046
862962008360	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
862962008361	DNA topoisomerase III; Provisional; Region: PRK07726
862962008362	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
862962008363	active site
862962008364	putative interdomain interaction site [polypeptide binding]; other site
862962008365	putative metal-binding site [ion binding]; other site
862962008366	putative nucleotide binding site [chemical binding]; other site
862962008367	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962008368	domain I; other site
862962008369	DNA binding groove [nucleotide binding]
862962008370	phosphate binding site [ion binding]; other site
862962008371	domain II; other site
862962008372	domain III; other site
862962008373	nucleotide binding site [chemical binding]; other site
862962008374	catalytic site [active]
862962008375	domain IV; other site
862962008376	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
862962008377	PS00070 Aldehyde dehydrogenases cysteine active site.
862962008378	HMMPfam hit to PF01131, DNA topoisomerase, score 1.7e-82
862962008379	HMMPfam hit to PF01751, Toprim domain, score 7.9e-13
862962008380	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
862962008381	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
862962008382	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
862962008383	Clostripain family; Region: Peptidase_C11; pfam03415
862962008384	Signal peptide predicted for BF638R2063 by SignalP 2.0 HMM (Signal peptide probability 0.676) with cleavage site probability 0.362 between residues 21 and 22
862962008385	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008386	2 probable transmembrane helices predicted for BF638R2064 by TMHMM2.0 at aa 13-30 and 35-54
862962008387	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008388	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962008389	active site
862962008390	DNA binding site [nucleotide binding]
862962008391	Int/Topo IB signature motif; other site
862962008392	HMMPfam hit to PF00589, Phage integrase family, score 8.9e-08
862962008393	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962008394	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962008395	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.4e-07
862962008396	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00076
862962008397	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962008398	Signal peptide predicted for BF638R2067 by SignalP 2.0 HMM (Signal peptide probability 0.676) with cleavage site probability 0.329 between residues 22 and 23
862962008399	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008400	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962008401	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962008402	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962008403	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962008404	Signal peptide predicted for BF638R2068 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.732 between residues 20 and 21
862962008405	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008406	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962008407	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962008408	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008409	Signal peptide predicted for BF638R2073 by SignalP 2.0 HMM (Signal peptide probability 0.924) with cleavage site probability 0.876 between residues 22 and 23
862962008410	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962008411	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
862962008412	putative active site [active]
862962008413	putative NTP binding site [chemical binding]; other site
862962008414	putative nucleic acid binding site [nucleotide binding]; other site
862962008415	Signal peptide predicted for BF638R2076 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.582 between residues 37 and 38
862962008416	5 probable transmembrane helices predicted for BF638R2076 by TMHMM2.0 at aa 17-39, 52-74, 94-116, 126-148 and 169-191
862962008418	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
862962008419	ParB-like nuclease domain; Region: ParB; smart00470
862962008420	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962008421	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962008422	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.82
862962008423	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0024
862962008424	RteC protein; Region: RteC; pfam09357
862962008425	YWFCY protein; Region: YWFCY; pfam14293
862962008426	AAA-like domain; Region: AAA_10; pfam12846
862962008427	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
862962008428	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008429	4 probable transmembrane helices predicted for BF638R2084 by TMHMM2.0 at aa 15-37, 58-80, 95-117 and 124-143
862962008430	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008431	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
862962008432	HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 8.8e-08
862962008433	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
862962008434	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962008435	P-loop; other site
862962008436	Magnesium ion binding site [ion binding]; other site
862962008437	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962008438	1 probable transmembrane helix predicted for BF638R2091 by TMHMM2.0 at aa 4-22
862962008439	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
862962008440	Signal peptide predicted for BF638R2092 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.762 between residues 21 and 22
862962008441	3 probable transmembrane helices predicted for BF638R2092 by TMHMM2.0 at aa 5-22, 42-64 and 76-98
862962008442	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
862962008443	2 probable transmembrane helices predicted for BF638R2093 by TMHMM2.0 at aa 24-46 and 50-72; 2 probable transmembrane helices predicted for BF638R2094 by TMHMM2.0 at aa 22-44 and 48-70
862962008444	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
862962008445	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
862962008446	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
862962008447	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008448	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008449	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
862962008450	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962008451	putative active site [active]
862962008452	putative NTP binding site [chemical binding]; other site
862962008453	putative nucleic acid binding site [nucleotide binding]; other site
862962008454	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
862962008455	Type II intron maturase; Region: Intron_maturas2; pfam01348
862962008456	HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent, score 4.1e-80
862962008457	HMMPfam hit to PF01348, Type II intron maturase, score 1.5e-08
862962008458	PS00190 Cytochrome c family heme-binding site signature.
862962008459	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962008460	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
862962008461	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
862962008462	Signal peptide predicted for BF638R2098 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.560 between residues 21 and 22
862962008463	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
862962008464	5 probable transmembrane helices predicted for BF638R2099 by TMHMM2.0 at aa 24-46, 67-89, 194-216, 229-251 and 271-293
862962008465	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008466	HMMPfam hit to PF07863, Homologues of TraJ from Bacteroides conju, score 5.9e-40
862962008467	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
862962008468	Signal peptide predicted for BF638R2100 by SignalP 2.0 HMM (Signal peptide probability 0.948) with cleavage site probability 0.838 between residues 42 and 43
862962008469	1 probable transmembrane helix predicted for BF638R2100 by TMHMM2.0 at aa 15-37
862962008470	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
862962008471	1 probable transmembrane helix predicted for BF638R2101 by TMHMM2.0 at aa 30-52
862962008472	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008473	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
862962008474	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
862962008475	1 probable transmembrane helix predicted for BF638R2102 by TMHMM2.0 at aa 48-67
862962008476	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
862962008477	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
862962008478	Signal peptide predicted for BF638R2103 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 19 and 20
862962008479	Conjugative transposon protein TraO; Region: TraO; pfam10626
862962008480	Signal peptide predicted for BF638R2104 by SignalP 2.0 HMM (Signal peptide probability 0.897) with cleavage site probability 0.449 between residues 22 and 23
862962008481	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
862962008482	Signal peptide predicted for BF638R2105 by SignalP 2.0 HMM (Signal peptide probability 0.601) with cleavage site probability 0.530 between residues 22 and 23
862962008483	Domain of unknown function, B. Theta Gene description (DUF3873); Region: DUF3873; pfam12989
862962008484	Protein of unknown function (DUF1273); Region: DUF1273; cl01859
862962008485	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
862962008486	active site
862962008487	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
862962008488	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962008489	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962008490	Int/Topo IB signature motif; other site
862962008491	HMMPfam hit to PF00589, Phage integrase family, score 1.2e-07
862962008492	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
862962008493	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962008494	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962008495	ABC transporter; Region: ABC_tran_2; pfam12848
862962008496	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962008497	HMMPfam hit to PF00005, ABC transporter, score 8.3e-57
862962008498	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008499	PS00211 ABC transporters family signature.
862962008500	HMMPfam hit to PF00005, ABC transporter, score 4.1e-39
862962008501	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008502	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008503	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962008504	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008505	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008506	Signal peptide predicted for BF638R2117 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.926 between residues 24 and 25
862962008507	1 probable transmembrane helix predicted for BF638R2117 by TMHMM2.0 at aa 5-27
862962008508	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.2e-11
862962008509	HMMPfam hit to PF00593, TonB dependent receptor, score 3e-12
862962008510	Signal peptide predicted for BF638R2118 by SignalP 2.0 HMM (Signal peptide probability 0.697) with cleavage site probability 0.641 between residues 22 and 23
862962008511	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008512	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008513	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
862962008514	putative catalytic site [active]
862962008515	putative metal binding site [ion binding]; other site
862962008516	putative phosphate binding site [ion binding]; other site
862962008517	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 9e-25
862962008518	3 probable transmembrane helices predicted for BF638R2119 by TMHMM2.0 at aa 9-31, 41-63 and 68-85
862962008519	Signal peptide predicted for BF638R2119 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.414 between residues 27 and 28
862962008520	PAS domain; Region: PAS_9; pfam13426
862962008521	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
862962008522	putative active site [active]
862962008523	heme pocket [chemical binding]; other site
862962008524	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962008525	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962008526	dimer interface [polypeptide binding]; other site
862962008527	phosphorylation site [posttranslational modification]
862962008528	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962008529	ATP binding site [chemical binding]; other site
862962008530	Mg2+ binding site [ion binding]; other site
862962008531	G-X-G motif; other site
862962008532	Response regulator receiver domain; Region: Response_reg; pfam00072
862962008533	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962008534	active site
862962008535	phosphorylation site [posttranslational modification]
862962008536	intermolecular recognition site; other site
862962008537	dimerization interface [polypeptide binding]; other site
862962008538	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.5e-23
862962008539	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 4.3e-36
862962008540	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.3e-24
862962008541	PS00018 EF-hand calcium-binding domain.
862962008542	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
862962008543	CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; Region: CESA_like_1; cd06439
862962008544	DXD motif; other site
862962008545	4 probable transmembrane helices predicted for BF638R2121 by TMHMM2.0 at aa 13-35, 307-329, 331-353 and 363-385
862962008546	HMMPfam hit to PF00535, Glycosyl transferase, score 2.3e-11
862962008547	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962008548	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962008549	active site
862962008550	HMMPfam hit to PF00535, Glycosyl transferase, score 9.6e-23
862962008551	glycosyltransferase, SP_1767 family; Region: glyco_access_1; TIGR03728
862962008552	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
862962008553	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
862962008554	putative ADP-binding pocket [chemical binding]; other site
862962008555	HMMPfam hit to PF00534, Glycosyl transferases group, score 2.8e-48
862962008556	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008557	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962008558	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
862962008559	12 probable transmembrane helices predicted for BF638R2125 by TMHMM2.0 at aa 12-34, 44-66, 78-100, 115-137, 144-163, 167-189, 291-313, 328-350, 355-377, 381-403, 416-438 and 443-465
862962008560	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1.5e-32
862962008561	putative glycosyl transferase; Provisional; Region: PRK10073
862962008562	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962008563	active site
862962008564	HMMPfam hit to PF00535, Glycosyl transferase, score 6.1e-35
862962008565	1 probable transmembrane helix predicted for BF638R2128 by TMHMM2.0 at aa 56-78
862962008566	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962008567	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
862962008568	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
862962008569	DXD motif; other site
862962008570	4 probable transmembrane helices predicted for BF638R2129 by TMHMM2.0 at aa 7-29, 323-340, 347-364 and 374-392
862962008571	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
862962008572	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
862962008573	Probable Catalytic site; other site
862962008574	metal-binding site
862962008575	HMMPfam hit to PF00535, Glycosyl transferase, score 5.2e-25
862962008576	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
862962008577	10 probable transmembrane helices predicted for BF638R2131 by TMHMM2.0 at aa 21-40, 44-63, 76-93, 98-120, 133-150, 191-209, 216-238, 258-277, 354-376 and 386-403
862962008578	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
862962008579	2 probable transmembrane helices predicted for BF638R2132 by TMHMM2.0 at aa 12-31 and 478-500
862962008580	Outer membrane efflux protein; Region: OEP; pfam02321
862962008581	Signal peptide predicted for BF638R2133 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.545 between residues 24 and 25
862962008582	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962008583	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008584	1 probable transmembrane helix predicted for BF638R2134 by TMHMM2.0 at aa 12-29
862962008585	Signal peptide predicted for BF638R2134 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.758 between residues 28 and 29
862962008586	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
862962008587	trimer interface [polypeptide binding]; other site
862962008588	active site
862962008589	G bulge; other site
862962008590	Signal peptide predicted for BF638R2135 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.736 between residues 37 and 38
862962008591	HMMPfam hit to PF03051, Peptidase C1-like family, score 1.4e-143
862962008592	PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site.
862962008593	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
862962008594	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
862962008595	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
862962008596	HMMPfam hit to PF05896, Na(+)-translocating NADH-quinone reductase s, score 1.9e-182
862962008597	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
862962008598	HMMPfam hit to PF03116, NQR2, RnfD, RnfE family, score 4.6e-114
862962008599	10 probable transmembrane helices predicted for BF638R2137 by TMHMM2.0 at aa 60-82, 97-119, 131-153, 168-185, 205-227, 242-264, 271-288, 298-320, 333-350 and 354-376
862962008600	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
862962008601	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
862962008602	Signal peptide predicted for BF638R2138 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.678 between residues 32 and 33
862962008603	1 probable transmembrane helix predicted for BF638R2138 by TMHMM2.0 at aa 7-29
862962008604	HMMPfam hit to PF04205, FMN-binding domain, score 4.4e-22
862962008605	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
862962008606	HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 1.3e-72
862962008607	5 probable transmembrane helices predicted for BF638R2139 by TMHMM2.0 at aa 43-65, 72-91, 101-123, 136-158 and 178-200
862962008608	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008609	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
862962008610	HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 6.6e-87
862962008611	6 probable transmembrane helices predicted for BF638R2140 by TMHMM2.0 at aa 12-31, 37-59, 72-94, 109-128, 148-170 and 185-207
862962008612	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
862962008613	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
862962008614	catalytic loop [active]
862962008615	iron binding site [ion binding]; other site
862962008616	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
862962008617	FAD binding pocket [chemical binding]; other site
862962008618	FAD binding motif [chemical binding]; other site
862962008619	phosphate binding motif [ion binding]; other site
862962008620	beta-alpha-beta structure motif; other site
862962008621	NAD binding pocket [chemical binding]; other site
862962008622	Signal peptide predicted for BF638R2141 by SignalP 2.0 HMM (Signal peptide probability 0.837) with cleavage site probability 0.464 between residues 26 and 27
862962008623	1 probable transmembrane helix predicted for BF638R2141 by TMHMM2.0 at aa 3-25
862962008624	HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 2.3e-08
862962008625	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008626	HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 5.8e-12
862962008627	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
862962008628	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
862962008629	ATP binding site [chemical binding]; other site
862962008630	putative Mg++ binding site [ion binding]; other site
862962008631	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962008632	nucleotide binding region [chemical binding]; other site
862962008633	ATP-binding site [chemical binding]; other site
862962008634	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
862962008635	RNA binding site [nucleotide binding]; other site
862962008636	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 7.4e-44
862962008637	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.9e-29
862962008638	HMMPfam hit to PF03880, DbpA RNA binding domain, score 2.1e-11
862962008639	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
862962008640	homodimer interface [polypeptide binding]; other site
862962008641	substrate-cofactor binding pocket; other site
862962008642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962008643	catalytic residue [active]
862962008644	HMMPfam hit to PF00266, Aminotransferase class-V, score 5.1e-29
862962008645	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
862962008646	putative ligand binding site [chemical binding]; other site
862962008647	putative NAD binding site [chemical binding]; other site
862962008648	putative catalytic site [active]
862962008649	HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 3.3e-20
862962008650	HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.1e-26
862962008651	Uncharacterized conserved protein [Function unknown]; Region: COG4198
862962008652	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
862962008653	HMMPfam hit to PF06245, Protein of unknown function (DUF1015), score 6.5e-181
862962008654	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008655	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
862962008656	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
862962008657	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 6.2e-35
862962008658	Uncharacterized conserved protein [Function unknown]; Region: COG1739
862962008659	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
862962008660	HMMPfam hit to PF01205, Uncharacterized protein family UPF0029, score 5.5e-41
862962008661	PS00910 Uncharacterized protein family UPF0029 signature.
862962008662	HpaII restriction endonuclease; Region: RE_HpaII; pfam09561
862962008663	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
862962008664	FMN binding site [chemical binding]; other site
862962008665	dimer interface [polypeptide binding]; other site
862962008666	HMMPfam hit to PF00881, Nitroreductase family, score 1.1e-15
862962008667	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008668	glycine dehydrogenase; Provisional; Region: PRK05367
862962008669	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
862962008670	tetramer interface [polypeptide binding]; other site
862962008671	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962008672	catalytic residue [active]
862962008673	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
862962008674	tetramer interface [polypeptide binding]; other site
862962008675	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962008676	catalytic residue [active]
862962008677	PS00659 Glycosyl hydrolases family 5 signature.
862962008678	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008679	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008680	HMMPfam hit to PF02347, Glycine cleavage system P-protein, score 1.2e-217
862962008681	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
862962008682	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.1e-37
862962008683	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
862962008684	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962008685	S-adenosylmethionine binding site [chemical binding]; other site
862962008686	HMMPfam hit to PF02527, Glucose inhibited division protein, score 6.1e-32
862962008687	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
862962008688	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
862962008689	1 probable transmembrane helix predicted for BF638R2153 by TMHMM2.0 at aa 21-40
862962008690	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008691	Signal peptide predicted for BF638R2154 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.562 between residues 45 and 46
862962008692	1 probable transmembrane helix predicted for BF638R2154 by TMHMM2.0 at aa 30-52
862962008693	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008694	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008695	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
862962008696	Signal peptide predicted for BF638R2155 by SignalP 2.0 HMM (Signal peptide probability 0.928) with cleavage site probability 0.830 between residues 15 and 16
862962008697	HMMPfam hit to PF00593, TonB dependent receptor, score 2.1e-20
862962008698	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
862962008699	metal-binding site [ion binding]
862962008700	Signal peptide predicted for BF638R2156 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 22 and 23
862962008701	HMMPfam hit to PF00403, Heavy-metal-associated domain, score 0.026
862962008702	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
862962008703	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
862962008704	metal-binding site [ion binding]
862962008705	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
862962008706	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962008707	motif II; other site
862962008708	HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.1e-14
862962008709	PS01047 Heavy-metal-associated domain.
862962008710	8 probable transmembrane helices predicted for BF638R2157 by TMHMM2.0 at aa 96-118, 122-143, 156-178, 188-205, 339-361, 376-398, 683-705 and 709-731
862962008711	HMMPfam hit to PF00122, E1-E2 ATPase, score 3.7e-102
862962008712	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008713	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.8e-36
862962008714	PS00154 E1-E2 ATPases phosphorylation site.
862962008715	PS01229 Hypothetical cof family signature 2.
862962008716	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962008717	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962008718	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.9e-08
862962008719	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.6
862962008720	lipoate-protein ligase B; Provisional; Region: PRK14348
862962008721	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 2.7e-29
862962008722	PS01313 Lipoate-protein ligase B signature.
862962008723	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
862962008724	HMMPfam hit to PF07313, Protein of unknown function (DUF1460), score 2.7e-82
862962008725	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008726	Signal peptide predicted for BF638R2161 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.981 between residues 20 and 21
862962008727	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
862962008728	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962008729	Signal peptide predicted for BF638R2162 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.853 between residues 18 and 19
862962008730	putative oligopeptide transporter, OPT family; Region: TIGR00733
862962008731	OPT oligopeptide transporter protein; Region: OPT; pfam03169
862962008732	17 probable transmembrane helices predicted for BF638R2163 by TMHMM2.0 at aa 38-60, 64-86, 99-121, 131-153, 189-211, 231-250, 257-279, 299-321, 355-377, 387-409, 416-437, 442-464, 485-502, 530-552, 559-581, 601-620 and 633-655
862962008733	HMMPfam hit to PF03169, OPT oligopeptide transporter protein, score 4.7e-09
862962008734	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008735	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962008736	HMMPfam hit to PF07610, Protein of unknown function (DUF1573), score 1.7e-25
862962008737	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008738	Signal peptide predicted for BF638R2164 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.982 between residues 20 and 21
862962008739	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
862962008740	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962008741	ATP binding site [chemical binding]; other site
862962008742	Mg2+ binding site [ion binding]; other site
862962008743	G-X-G motif; other site
862962008744	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.5e-32
862962008745	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0044
862962008746	2 probable transmembrane helices predicted for BF638R2165 by TMHMM2.0 at aa 9-28 and 32-54
862962008747	Signal peptide predicted for BF638R2165 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.727 between residues 39 and 40
862962008748	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962008749	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962008750	active site
862962008751	phosphorylation site [posttranslational modification]
862962008752	intermolecular recognition site; other site
862962008753	dimerization interface [polypeptide binding]; other site
862962008754	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962008755	Walker A motif; other site
862962008756	ATP binding site [chemical binding]; other site
862962008757	Walker B motif; other site
862962008758	arginine finger; other site
862962008759	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962008760	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 1.9e-12
862962008761	PS00688 Sigma-54 interaction domain C-terminal part signature.
862962008762	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 4.6e-123
862962008763	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.8e-21
862962008764	Signal peptide predicted for BF638R2167 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.591 between residues 23 and 24
862962008765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008766	1 probable transmembrane helix predicted for BF638R2167 by TMHMM2.0 at aa 112-134
862962008767	PS00430 TonB-dependent receptor proteins signature 1.
862962008768	Signal peptide predicted for BF638R2168 by SignalP 2.0 HMM (Signal peptide probability 0.738) with cleavage site probability 0.334 between residues 23 and 24
862962008769	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962008770	FtsX-like permease family; Region: FtsX; pfam02687
862962008771	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
862962008772	FtsX-like permease family; Region: FtsX; pfam02687
862962008773	8 probable transmembrane helices predicted for BF638R2169 by TMHMM2.0 at aa 21-43, 289-311, 336-358, 383-405, 426-448, 684-706, 736-758 and 768-790
862962008774	HMMPfam hit to PF02687, Predicted permease, score 3.1e-20
862962008775	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008776	HMMPfam hit to PF02687, Predicted permease, score 3.8e-16
862962008777	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962008778	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962008779	Walker A/P-loop; other site
862962008780	ATP binding site [chemical binding]; other site
862962008781	Q-loop/lid; other site
862962008782	ABC transporter signature motif; other site
862962008783	Walker B; other site
862962008784	D-loop; other site
862962008785	H-loop/switch region; other site
862962008786	HMMPfam hit to PF00005, ABC transporter, score 1.3e-61
862962008787	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008788	PS00211 ABC transporters family signature.
862962008789	Signal peptide predicted for BF638R2171 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.555 between residues 22 and 23
862962008790	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
862962008791	G1 box; other site
862962008792	GTP/Mg2+ binding site [chemical binding]; other site
862962008793	Switch I region; other site
862962008794	G2 box; other site
862962008795	G3 box; other site
862962008796	Switch II region; other site
862962008797	G4 box; other site
862962008798	G5 box; other site
862962008799	HMMPfam hit to PF01926, GTPase of unknown function, score 4.5e-28
862962008800	PS00017 ATP/GTP-binding site motif A (P-loop).
862962008801	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
862962008802	Na binding site [ion binding]; other site
862962008803	12 probable transmembrane helices predicted for BF638R2173 by TMHMM2.0 at aa 4-21, 42-64, 74-96, 117-139, 149-168, 175-197, 232-249, 273-295, 315-337, 372-391, 396-418 and 455-474
862962008804	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
862962008805	HMMPfam hit to PF04140, Isoprenylcysteine carboxyl methyltransferase, score 4e-39
862962008806	4 probable transmembrane helices predicted for BF638R2174 by TMHMM2.0 at aa 4-23, 35-57, 67-89 and 122-144
862962008807	Signal peptide predicted for BF638R2175 by SignalP 2.0 HMM (Signal peptide probability 0.603) with cleavage site probability 0.283 between residues 23 and 24
862962008808	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008809	recombination protein RecR; Reviewed; Region: recR; PRK00076
862962008810	RecR protein; Region: RecR; pfam02132
862962008811	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
862962008812	putative active site [active]
862962008813	putative metal-binding site [ion binding]; other site
862962008814	tetramer interface [polypeptide binding]; other site
862962008815	HMMPfam hit to PF02132, RecR protein, score 8.7e-12
862962008816	PS01300 RecR protein signature.
862962008817	PS00190 Cytochrome c family heme-binding site signature.
862962008818	HMMPfam hit to PF01751, Toprim domain, score 0.00044
862962008819	4 probable transmembrane helices predicted for BF638R2177 by TMHMM2.0 at aa 17-39, 49-71, 84-106 and 111-133
862962008820	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
862962008821	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
862962008822	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.8e-09
862962008823	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
862962008824	HMMPfam hit to PF02622, Uncharacterized ACR, COG1678, score 6.9e-38
862962008825	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962008826	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962008827	homodimer interface [polypeptide binding]; other site
862962008828	catalytic residue [active]
862962008829	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962008830	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962008831	active site
862962008832	catalytic tetrad [active]
862962008833	HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.1e-54
862962008834	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
862962008835	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
862962008836	HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 1.3e-10
862962008837	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962008838	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962008839	active site
862962008840	catalytic tetrad [active]
862962008841	HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.9e-111
862962008842	PS00798 Aldo/keto reductase family signature 1.
862962008843	PS00062 Aldo/keto reductase family signature 2.
862962008844	PS00063 Aldo/keto reductase family putative active site signature.
862962008846	HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.7e-08
862962008847	PS00062 Aldo/keto reductase family signature 2.
862962008848	PS00063 Aldo/keto reductase family putative active site signature.
862962008849	Protein of unknown function (DUF3737); Region: DUF3737; pfam12541
862962008850	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962008851	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
862962008852	10 probable transmembrane helices predicted for BF638R2188 by TMHMM2.0 at aa 28-50, 55-77, 111-133, 148-170, 177-199, 219-241, 287-309, 344-366, 398-420 and 445-467
862962008853	HMMPfam hit to PF01554, MatE, score 1.7e-22
862962008854	HMMPfam hit to PF01554, MatE, score 8.3e-26
862962008855	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
862962008856	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962008857	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962008858	homodimer interface [polypeptide binding]; other site
862962008859	catalytic residue [active]
862962008860	HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.6e-18
862962008861	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962008862	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962008863	active site
862962008864	catalytic tetrad [active]
862962008865	HMMPfam hit to PF00248, Aldo/keto reductase family, score 3.1e-45
862962008866	Amidohydrolase; Region: Amidohydro_2; pfam04909
862962008867	active site
862962008868	Signal peptide predicted for BF638R2191 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.576 between residues 21 and 22
862962008869	HMMPfam hit to PF04909, Amidohydrolase, score 2.1e-29
862962008870	short chain dehydrogenase; Provisional; Region: PRK06940
862962008871	classical (c) SDRs; Region: SDR_c; cd05233
862962008872	NAD(P) binding site [chemical binding]; other site
862962008873	active site
862962008874	HMMPfam hit to PF00106, short chain dehydrogenase, score 4.2e-08
862962008875	Cupin domain; Region: Cupin_2; cl17218
862962008876	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962008877	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962008878	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00013
862962008879	PS00041 Bacterial regulatory proteins, araC family signature.
862962008880	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.079
862962008881	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
862962008882	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
862962008883	Signal peptide predicted for BF638R2194 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.972 between residues 20 and 21
862962008884	HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 1.7e-29
862962008885	HMMPfam hit to PF07883, Cupin domain, score 0.00015
862962008886	flavodoxin; Provisional; Region: PRK07116
862962008887	Signal peptide predicted for BF638R2195 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.649 between residues 20 and 21
862962008888	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008889	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
862962008890	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
862962008891	maltose O-acetyltransferase; Provisional; Region: PRK10092
862962008892	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
862962008893	CoA binding site [chemical binding]; other site
862962008894	active site
862962008895	trimer interface [polypeptide binding]; other site
862962008896	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 20
862962008897	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.12
862962008898	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
862962008899	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
862962008900	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 0.0012
862962008901	Predicted membrane protein [Function unknown]; Region: COG2311
862962008902	short chain dehydrogenase; Provisional; Region: PRK06172
862962008903	classical (c) SDRs; Region: SDR_c; cd05233
862962008904	NAD(P) binding site [chemical binding]; other site
862962008905	active site
862962008906	Signal peptide predicted for BF638R2200 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.562 between residues 27 and 28
862962008907	HMMPfam hit to PF00106, short chain dehydrogenase, score 9.9e-75
862962008908	Signal peptide predicted for BF638R2201 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.891 between residues 36 and 37
862962008909	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962008910	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962008911	active site
862962008912	catalytic tetrad [active]
862962008913	HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.8e-40
862962008914	RibD C-terminal domain; Region: RibD_C; cl17279
862962008915	HMMPfam hit to PF01872, RibD C-terminal domain, score 1.8e-08
862962008916	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
862962008917	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962008918	Signal peptide predicted for BF638R2203 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 19 and 20
862962008919	HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.0017
862962008920	Predicted membrane protein [Function unknown]; Region: COG2311
862962008921	Protein of unknown function (DUF418); Region: DUF418; cl12135
862962008922	Protein of unknown function (DUF418); Region: DUF418; pfam04235
862962008923	HMMPfam hit to PF04171, Protein of unknown function (DUF405), score 3e-41
862962008924	8 probable transmembrane helices predicted for BF638R2204 by TMHMM2.0 at aa 24-46, 76-95, 115-137, 152-174, 259-281, 296-318, 344-366 and 370-392
862962008925	HMMPfam hit to PF04235, Protein of unknown function (DUF418), score 1.5e-40
862962008926	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962008927	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962008928	active site
862962008929	catalytic tetrad [active]
862962008930	HMMPfam hit to PF00248, Aldo/keto reductase family, score 1e-44
862962008931	1 probable transmembrane helix predicted for BF638R2207 by TMHMM2.0 at aa 25-47
862962008932	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962008933	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
862962008934	putative membrane fusion protein; Region: TIGR02828
862962008935	Signal peptide predicted for BF638R2209 by SignalP 2.0 HMM (Signal peptide probability 0.959) with cleavage site probability 0.352 between residues 19 and 20
862962008936	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008937	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962008938	Protein export membrane protein; Region: SecD_SecF; cl14618
862962008939	Signal peptide predicted for BF638R2210 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.668 between residues 31 and 32
862962008940	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 6.1e-291
862962008941	10 probable transmembrane helices predicted for BF638R2210 by TMHMM2.0 at aa 13-32, 363-385, 444-466, 476-498, 536-555, 859-881, 888-910, 914-936, 962-984 and 999-1021
862962008942	Outer membrane efflux protein; Region: OEP; pfam02321
862962008943	Outer membrane efflux protein; Region: OEP; pfam02321
862962008944	Signal peptide predicted for BF638R2211 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.957 between residues 18 and 19
862962008945	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.004
862962008946	HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.9e-10
862962008947	2 probable transmembrane helices predicted for BF638R2212 by TMHMM2.0 at aa 20-39 and 54-76
862962008948	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
862962008949	Active site serine [active]
862962008950	HMMPfam hit to PF03572, Peptidase family S41, score 1.2e-07
862962008951	Signal peptide predicted for BF638R2213 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.554 between residues 28 and 29
862962008952	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008953	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962008954	Signal peptide predicted for BF638R2214 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.931 between residues 30 and 31
862962008955	1 probable transmembrane helix predicted for BF638R2214 by TMHMM2.0 at aa 13-30
862962008956	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962008957	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962008958	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962008959	Signal peptide predicted for BF638R2216 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.933 between residues 21 and 22
862962008960	Signal peptide predicted for BF638R2217 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.772 between residues 17 and 18
862962008961	Signal peptide predicted for BF638R2218 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.445 between residues 23 and 24
862962008962	HMMPfam hit to PF00560, Leucine Rich Repeat, score 11
862962008963	HMMPfam hit to PF00560, Leucine Rich Repeat, score 23
862962008964	Signal peptide predicted for BF638R2219 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.861 between residues 23 and 24
862962008965	1 probable transmembrane helix predicted for BF638R2219 by TMHMM2.0 at aa 5-27
862962008966	Signal peptide predicted for BF638R2220 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.962 between residues 25 and 26
862962008967	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008968	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962008969	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
862962008970	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962008971	N-terminal plug; other site
862962008972	ligand-binding site [chemical binding]; other site
862962008973	Signal peptide predicted for BF638R2221 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.445 between residues 20 and 21
862962008974	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.2e-18
862962008975	HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-25
862962008976	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
862962008977	Signal peptide predicted for BF638R2222 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.894 between residues 26 and 27
862962008978	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008979	8 probable transmembrane helices predicted for BF638R2223 by TMHMM2.0 at aa 24-46, 56-78, 85-107, 139-161, 182-204, 214-233, 240-259 and 279-301
862962008980	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008981	Signal peptide predicted for BF638R2224 by SignalP 2.0 HMM (Signal peptide probability 0.953) with cleavage site probability 0.691 between residues 27 and 28
862962008982	8 probable transmembrane helices predicted for BF638R2224 by TMHMM2.0 at aa 7-29, 39-61, 68-90, 110-132, 165-187, 197-214, 227-249 and 264-286
862962008983	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962008984	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962008985	Signal peptide predicted for BF638R2225 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 21 and 22
862962008986	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962008987	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962008988	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-17
862962008989	PS01081 Bacterial regulatory proteins, tetR family signature.
862962008990	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
862962008991	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
862962008992	HMMPfam hit to PF02409, O-methyltransferase N-terminus, score 1.4e-14
862962008993	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962008994	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962008995	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962008996	Walker A/P-loop; other site
862962008997	ATP binding site [chemical binding]; other site
862962008998	Q-loop/lid; other site
862962008999	ABC transporter signature motif; other site
862962009000	Walker B; other site
862962009001	D-loop; other site
862962009002	H-loop/switch region; other site
862962009003	Signal peptide predicted for BF638R2228 by SignalP 2.0 HMM (Signal peptide probability 0.857) with cleavage site probability 0.417 between residues 40 and 41
862962009004	6 probable transmembrane helices predicted for BF638R2228 by TMHMM2.0 at aa 24-46, 69-91, 142-164, 169-191, 257-279 and 289-308
862962009005	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 8.5e-06
862962009006	HMMPfam hit to PF00005, ABC transporter, score 2.7e-51
862962009007	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009008	PS00211 ABC transporters family signature.
862962009009	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962009010	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962009011	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962009012	Walker A/P-loop; other site
862962009013	ATP binding site [chemical binding]; other site
862962009014	Q-loop/lid; other site
862962009015	ABC transporter signature motif; other site
862962009016	Walker B; other site
862962009017	D-loop; other site
862962009018	H-loop/switch region; other site
862962009019	6 probable transmembrane helices predicted for BF638R2229 by TMHMM2.0 at aa 20-42, 57-76, 136-158, 162-181, 241-263 and 268-290
862962009020	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1e-08
862962009021	HMMPfam hit to PF00005, ABC transporter, score 1.8e-63
862962009022	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009023	PS00211 ABC transporters family signature.
862962009024	PAS fold; Region: PAS_3; pfam08447
862962009025	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009026	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962009027	dimer interface [polypeptide binding]; other site
862962009028	phosphorylation site [posttranslational modification]
862962009029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009030	ATP binding site [chemical binding]; other site
862962009031	Mg2+ binding site [ion binding]; other site
862962009032	G-X-G motif; other site
862962009033	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.3e-34
862962009034	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.8e-18
862962009035	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962009036	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962009037	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.068
862962009038	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-11
862962009039	Protein of unknown function (DUF2000); Region: DUF2000; pfam09391
862962009040	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009041	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
862962009042	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
862962009043	dimerization interface [polypeptide binding]; other site
862962009044	putative DNA binding site [nucleotide binding]; other site
862962009045	putative Zn2+ binding site [ion binding]; other site
862962009046	AsnC family; Region: AsnC_trans_reg; pfam01037
862962009047	HMMPfam hit to PF01037, AsnC family, score 1.7e-39
862962009048	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962009049	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962009050	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 8.3e-09
862962009051	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.042
862962009052	PS00018 EF-hand calcium-binding domain.
862962009053	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
862962009054	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
862962009055	Active Sites [active]
862962009056	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
862962009057	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
862962009058	ParB-like nuclease domain; Region: ParB; smart00470
862962009059	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962009060	Signal peptide predicted for BF638R2240 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.649 between residues 19 and 20
862962009061	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
862962009062	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962009063	ligand binding site [chemical binding]; other site
862962009064	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962009065	binding surface
862962009066	TPR motif; other site
862962009067	TPR repeat; Region: TPR_11; pfam13414
862962009068	Signal peptide predicted for BF638R2241 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 23 and 24
862962009069	1 probable transmembrane helix predicted for BF638R2241 by TMHMM2.0 at aa 7-24
862962009070	HMMPfam hit to PF00691, OmpA family, score 0.00023
862962009071	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0027
862962009072	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
862962009073	Signal peptide predicted for BF638R2242 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.756 between residues 25 and 26
862962009074	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009075	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962009076	Signal peptide predicted for BF638R2243 by SignalP 2.0 HMM (Signal peptide probability 0.793) with cleavage site probability 0.454 between residues 25 and 26
862962009077	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962009078	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
862962009079	NAD binding site [chemical binding]; other site
862962009080	putative substrate binding site 2 [chemical binding]; other site
862962009081	putative substrate binding site 1 [chemical binding]; other site
862962009082	active site
862962009083	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 5.3e-31
862962009084	Response regulator receiver domain; Region: Response_reg; pfam00072
862962009085	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009086	active site
862962009087	phosphorylation site [posttranslational modification]
862962009088	intermolecular recognition site; other site
862962009089	dimerization interface [polypeptide binding]; other site
862962009090	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009091	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962009092	dimer interface [polypeptide binding]; other site
862962009093	phosphorylation site [posttranslational modification]
862962009094	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009095	ATP binding site [chemical binding]; other site
862962009096	Mg2+ binding site [ion binding]; other site
862962009097	G-X-G motif; other site
862962009098	HMMPfam hit to PF00072, Response regulator receiver domain, score 3.2e-38
862962009099	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0017
862962009100	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 7.1e-29
862962009101	probable DNA repair protein; Region: TIGR03623
862962009102	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
862962009103	Part of AAA domain; Region: AAA_19; pfam13245
862962009104	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
862962009105	Family description; Region: UvrD_C_2; pfam13538
862962009106	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
862962009107	HMMPfam hit to PF00580, UvrD/REP helicase, score 1.2e-12
862962009108	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009109	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962009110	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962009111	active site
862962009112	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyti, score 2.4e-135
862962009113	Signal peptide predicted for BF638R2251 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.931 between residues 18 and 19
862962009114	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
862962009115	active site
862962009116	Signal peptide predicted for BF638R2252 by SignalP 2.0 HMM (Signal peptide probability 0.888) with cleavage site probability 0.437 between residues 29 and 30
862962009117	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962009118	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962009119	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962009120	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962009121	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962009122	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962009123	Signal peptide predicted for BF638R2253 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.883 between residues 21 and 22
862962009124	1 probable transmembrane helix predicted for BF638R2253 by TMHMM2.0 at aa 5-22
862962009125	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-16
862962009126	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962009127	HMMPfam hit to PF00593, TonB dependent receptor, score 2.1e-14
862962009128	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962009129	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962009130	Signal peptide predicted for BF638R2254 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.882 between residues 18 and 19
862962009131	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009132	hypothetical protein; Provisional; Region: yieM; PRK10997
862962009133	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
862962009134	metal ion-dependent adhesion site (MIDAS); other site
862962009135	MoxR-like ATPases [General function prediction only]; Region: COG0714
862962009136	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962009137	Walker A motif; other site
862962009138	ATP binding site [chemical binding]; other site
862962009139	Walker B motif; other site
862962009140	arginine finger; other site
862962009141	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 5.9e-44
862962009142	HMMPfam hit to PF07726, ATPase family associated with various cellul, score 2.3e-05
862962009143	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
862962009144	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
862962009145	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962009146	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962009147	acyl-activating enzyme (AAE) consensus motif; other site
862962009148	acyl-activating enzyme (AAE) consensus motif; other site
862962009149	AMP binding site [chemical binding]; other site
862962009150	active site
862962009151	CoA binding site [chemical binding]; other site
862962009152	HMMPfam hit to PF00501, AMP-binding enzyme, score 1.7e-79
862962009153	PS00455 Putative AMP-binding domain signature.
862962009154	1 probable transmembrane helix predicted for BF638R2259 by TMHMM2.0 at aa 72-94
862962009155	potassium/proton antiporter; Reviewed; Region: PRK05326
862962009156	TrkA-C domain; Region: TrkA_C; pfam02080
862962009157	11 probable transmembrane helices predicted for BF638R2260 by TMHMM2.0 at aa 5-24, 31-53, 58-77, 89-111, 126-148, 191-213, 233-255, 276-298, 308-330, 343-365 and 376-398
862962009158	HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 1.5e-54
862962009159	Signal peptide predicted for BF638R2260 by SignalP 2.0 HMM (Signal peptide probability 0.658) with cleavage site probability 0.608 between residues 25 and 26
862962009160	uracil-xanthine permease; Region: ncs2; TIGR00801
862962009161	HMMPfam hit to PF00860, Permease family, score 2.2e-100
862962009162	10 probable transmembrane helices predicted for BF638R2261 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 114-136, 162-184, 212-234, 289-311, 316-338, 350-369 and 373-390
862962009163	PS01116 Xanthine/uracil permeases family signature.
862962009164	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009165	hybrid cluster protein; Provisional; Region: PRK05290
862962009166	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
862962009167	ACS interaction site; other site
862962009168	CODH interaction site; other site
862962009169	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
862962009170	hybrid metal cluster; other site
862962009171	HMMPfam hit to PF03063, Prismane/CO dehydrogenase family, score 2.8e-257
862962009172	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962009173	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962009174	ligand binding site [chemical binding]; other site
862962009175	flexible hinge region; other site
862962009176	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
862962009177	putative switch regulator; other site
862962009178	non-specific DNA interactions [nucleotide binding]; other site
862962009179	DNA binding site [nucleotide binding]
862962009180	sequence specific DNA binding site [nucleotide binding]; other site
862962009181	putative cAMP binding site [chemical binding]; other site
862962009182	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 0.00047
862962009183	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
862962009184	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009185	ATP binding site [chemical binding]; other site
862962009186	Mg2+ binding site [ion binding]; other site
862962009187	G-X-G motif; other site
862962009188	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.7e-23
862962009189	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0055
862962009190	2 probable transmembrane helices predicted for BF638R2264 by TMHMM2.0 at aa 12-31 and 35-57
862962009191	Signal peptide predicted for BF638R2264 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.857 between residues 31 and 32
862962009192	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962009193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009194	active site
862962009195	phosphorylation site [posttranslational modification]
862962009196	intermolecular recognition site; other site
862962009197	dimerization interface [polypeptide binding]; other site
862962009198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962009199	Walker A motif; other site
862962009200	ATP binding site [chemical binding]; other site
862962009201	Walker B motif; other site
862962009202	arginine finger; other site
862962009203	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962009204	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.4e-18
862962009205	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.1e-134
862962009206	HMMPfam hit to PF00072, Response regulator receiver domain, score 3.6e-19
862962009207	Signal peptide predicted for BF638R2266 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.779 between residues 30 and 31
862962009208	1 probable transmembrane helix predicted for BF638R2266 by TMHMM2.0 at aa 7-24
862962009209	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962009210	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
862962009211	active site
862962009212	metal binding site [ion binding]; metal-binding site
862962009213	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 7.7e-14
862962009214	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009215	Signal peptide predicted for BF638R2267 by SignalP 2.0 HMM (Signal peptide probability 0.889) with cleavage site probability 0.858 between residues 19 and 20
862962009216	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009217	FtsX-like permease family; Region: FtsX; pfam02687
862962009218	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009219	FtsX-like permease family; Region: FtsX; pfam02687
862962009220	Signal peptide predicted for BF638R2268 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.587 between residues 42 and 43
862962009221	8 probable transmembrane helices predicted for BF638R2268 by TMHMM2.0 at aa 19-41, 280-302, 323-345, 368-390, 413-435, 640-659, 691-713 and 723-745
862962009222	HMMPfam hit to PF02687, Predicted permease, score 2.1e-07
862962009223	HMMPfam hit to PF02687, Predicted permease, score 1.6e-10
862962009224	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962009225	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962009226	Walker A/P-loop; other site
862962009227	ATP binding site [chemical binding]; other site
862962009228	Q-loop/lid; other site
862962009229	ABC transporter signature motif; other site
862962009230	Walker B; other site
862962009231	D-loop; other site
862962009232	H-loop/switch region; other site
862962009233	HMMPfam hit to PF00005, ABC transporter, score 1.5e-58
862962009234	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009235	PS00211 ABC transporters family signature.
862962009236	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009237	FtsX-like permease family; Region: FtsX; pfam02687
862962009238	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009239	FtsX-like permease family; Region: FtsX; pfam02687
862962009240	Signal peptide predicted for BF638R2270 by SignalP 2.0 HMM (Signal peptide probability 0.781) with cleavage site probability 0.418 between residues 43 and 44
862962009241	8 probable transmembrane helices predicted for BF638R2270 by TMHMM2.0 at aa 20-42, 274-296, 325-347, 368-390, 413-435, 645-667, 698-717 and 730-752
862962009242	HMMPfam hit to PF02687, Predicted permease, score 3.3e-11
862962009243	HMMPfam hit to PF02687, Predicted permease, score 4e-14
862962009244	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962009245	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962009246	Walker A/P-loop; other site
862962009247	ATP binding site [chemical binding]; other site
862962009248	Q-loop/lid; other site
862962009249	ABC transporter signature motif; other site
862962009250	Walker B; other site
862962009251	D-loop; other site
862962009252	H-loop/switch region; other site
862962009253	HMMPfam hit to PF00005, ABC transporter, score 2.3e-60
862962009254	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009255	PS00211 ABC transporters family signature.
862962009256	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009257	FtsX-like permease family; Region: FtsX; pfam02687
862962009258	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009259	FtsX-like permease family; Region: FtsX; pfam02687
862962009260	Signal peptide predicted for BF638R2272 by SignalP 2.0 HMM (Signal peptide probability 0.815) with cleavage site probability 0.452 between residues 42 and 43
862962009261	8 probable transmembrane helices predicted for BF638R2272 by TMHMM2.0 at aa 19-41, 273-295, 324-346, 361-383, 412-434, 644-666, 692-714 and 729-751
862962009262	HMMPfam hit to PF02687, Predicted permease, score 5.6e-11
862962009263	HMMPfam hit to PF02687, Predicted permease, score 8e-12
862962009264	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009265	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962009266	FtsX-like permease family; Region: FtsX; pfam02687
862962009267	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962009268	FtsX-like permease family; Region: FtsX; pfam02687
862962009269	Signal peptide predicted for BF638R2273 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.501 between residues 40 and 41
862962009270	8 probable transmembrane helices predicted for BF638R2273 by TMHMM2.0 at aa 19-41, 283-305, 326-348, 372-394, 415-437, 642-661, 693-715 and 725-747
862962009271	HMMPfam hit to PF02687, Predicted permease, score 0.0002
862962009272	HMMPfam hit to PF02687, Predicted permease, score 8.9e-10
862962009273	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
862962009274	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962009275	12 probable transmembrane helices predicted for BF638R2274 by TMHMM2.0 at aa 22-44, 54-76, 97-119, 139-158, 171-193, 198-217, 238-260, 275-297, 318-340, 360-382, 394-416 and 420-442
862962009276	HMMPfam hit to PF01554, MatE, score 6.9e-22
862962009277	HMMPfam hit to PF01554, MatE, score 2.7e-19
862962009278	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
862962009279	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
862962009280	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962009281	motif II; other site
862962009282	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.7e-18
862962009283	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
862962009284	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
862962009285	quinone interaction residues [chemical binding]; other site
862962009286	active site
862962009287	catalytic residues [active]
862962009288	FMN binding site [chemical binding]; other site
862962009289	substrate binding site [chemical binding]; other site
862962009290	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 3.2e-58
862962009291	PS00911 Dihydroorotate dehydrogenase signature 1.
862962009292	PS00912 Dihydroorotate dehydrogenase signature 2.
862962009293	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
862962009294	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962009295	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
862962009296	oligomerization interface [polypeptide binding]; other site
862962009297	active site
862962009298	metal binding site [ion binding]; metal-binding site
862962009299	HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase, score 5.6e-135
862962009300	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962009301	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962009302	putative substrate translocation pore; other site
862962009303	Signal peptide predicted for BF638R2279 by SignalP 2.0 HMM (Signal peptide probability 0.776) with cleavage site probability 0.522 between residues 35 and 36
862962009304	12 probable transmembrane helices predicted for BF638R2279 by TMHMM2.0 at aa 13-35, 46-68, 75-94, 99-121, 133-155, 165-187, 208-230, 240-262, 269-288, 298-320, 333-355 and 360-382
862962009305	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.3e-29
862962009306	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962009307	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009308	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
862962009309	HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 1.6e-24
862962009310	3 probable transmembrane helices predicted for BF638R2280 by TMHMM2.0 at aa 29-51, 55-74 and 95-117
862962009311	HD domain; Region: HD_4; pfam13328
862962009312	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
862962009313	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
862962009314	synthetase active site [active]
862962009315	NTP binding site [chemical binding]; other site
862962009316	metal binding site [ion binding]; metal-binding site
862962009317	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
862962009318	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
862962009319	HMMPfam hit to PF01842, ACT domain, score 0.0013
862962009320	HMMPfam hit to PF02824, TGS domain, score 3.4e-23
862962009321	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 4.7e-45
862962009322	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
862962009323	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009324	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
862962009325	HMMPfam hit to PF00076, RNA recognition motif. (a.k.a. RRM, RBD, or, score 5e-27
862962009326	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962009327	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
862962009328	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
862962009329	ATP-grasp domain; Region: ATP-grasp; pfam02222
862962009330	HMMPfam hit to PF02222, ATP-grasp domain, score 6.3e-18
862962009331	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
862962009332	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
862962009333	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
862962009334	alpha subunit interaction interface [polypeptide binding]; other site
862962009335	Walker A motif; other site
862962009336	ATP binding site [chemical binding]; other site
862962009337	Walker B motif; other site
862962009338	inhibitor binding site; inhibition site
862962009339	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
862962009340	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 1.7e-26
862962009341	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 6.8e-82
862962009342	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009343	PS00152 ATP synthase alpha and beta subunits signature.
862962009344	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 1.5e-46
862962009345	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
862962009346	gamma subunit interface [polypeptide binding]; other site
862962009347	LBP interface [polypeptide binding]; other site
862962009348	HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta, score 1.1e-10
862962009349	Signal peptide predicted for BF638R2287 by SignalP 2.0 HMM (Signal peptide probability 0.809) with cleavage site probability 0.462 between residues 25 and 26
862962009350	4 probable transmembrane helices predicted for BF638R2287 by TMHMM2.0 at aa 13-32, 37-59, 71-93 and 103-125
862962009351	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962009352	ATP synthase A chain; Region: ATP-synt_A; cl00413
862962009353	Signal peptide predicted for BF638R2288 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 25 and 26
862962009354	8 probable transmembrane helices predicted for BF638R2288 by TMHMM2.0 at aa 7-24, 147-169, 176-194, 209-231, 238-260, 284-306, 313-335 and 350-372
862962009355	HMMPfam hit to PF00119, ATP synthase A chain, score 8.3e-22
862962009356	Signal peptide predicted for BF638R2289 by SignalP 2.0 HMM (Signal peptide probability 0.923) with cleavage site probability 0.811 between residues 24 and 25
862962009357	HMMPfam hit to PF00137, ATP synthase subunit C, score 8.3e-21
862962009358	2 probable transmembrane helices predicted for BF638R2289 by TMHMM2.0 at aa 20-42 and 62-84
862962009359	PS00605 ATP synthase c subunit signature.
862962009360	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
862962009361	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
862962009362	Signal peptide predicted for BF638R2290 by SignalP 2.0 HMM (Signal peptide probability 0.772) with cleavage site probability 0.627 between residues 23 and 24
862962009363	HMMPfam hit to PF00430, ATP synthase B/B' CF(0), score 2e-18
862962009364	1 probable transmembrane helix predicted for BF638R2290 by TMHMM2.0 at aa 10-32
862962009365	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13429
862962009366	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; COG0712
862962009367	HMMPfam hit to PF00213, ATP synthase delta (OSCP) subunit, score 3.6e-18
862962009368	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
862962009369	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
862962009370	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
862962009371	beta subunit interaction interface [polypeptide binding]; other site
862962009372	Walker A motif; other site
862962009373	ATP binding site [chemical binding]; other site
862962009374	Walker B motif; other site
862962009375	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
862962009376	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 9.9e-18
862962009377	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.4e-107
862962009378	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009379	PS00152 ATP synthase alpha and beta subunits signature.
862962009380	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 4.8e-15
862962009381	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
862962009382	core domain interface [polypeptide binding]; other site
862962009383	delta subunit interface [polypeptide binding]; other site
862962009384	epsilon subunit interface [polypeptide binding]; other site
862962009385	HMMPfam hit to PF00231, ATP synthase, score 8e-78
862962009386	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962009387	PIF1-like helicase; Region: PIF1; pfam05970
862962009388	Walker A motif; other site
862962009389	ATP binding site [chemical binding]; other site
862962009390	Walker B motif; other site
862962009391	Family description; Region: UvrD_C_2; pfam13538
862962009392	HRDC domain; Region: HRDC; pfam00570
862962009393	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009394	HMMPfam hit to PF00570, HRDC domain, score 3.4e-08
862962009395	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962009396	catalytic residues [active]
862962009397	HMMPfam hit to PF00085, Thioredoxin, score 4.2e-20
862962009398	PS00194 Thioredoxin family active site.
862962009399	Outer membrane efflux protein; Region: OEP; pfam02321
862962009400	Outer membrane efflux protein; Region: OEP; pfam02321
862962009401	Signal peptide predicted for BF638R2296 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.985 between residues 19 and 20
862962009402	HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.6e-09
862962009403	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0041
862962009404	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962009405	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
862962009406	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962009407	Signal peptide predicted for BF638R2297 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.387 between residues 21 and 22
862962009408	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009409	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962009410	Signal peptide predicted for BF638R2298 by SignalP 2.0 HMM (Signal peptide probability 0.670) with cleavage site probability 0.550 between residues 35 and 36
862962009411	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 8.9e-242
862962009412	12 probable transmembrane helices predicted for BF638R2298 by TMHMM2.0 at aa 17-34, 332-354, 361-383, 393-415, 446-465, 480-502, 534-553, 869-888, 895-917, 921-943, 967-989 and 999-1021
862962009413	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962009414	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009415	active site
862962009416	phosphorylation site [posttranslational modification]
862962009417	intermolecular recognition site; other site
862962009418	dimerization interface [polypeptide binding]; other site
862962009419	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962009420	DNA binding site [nucleotide binding]
862962009421	HMMPfam hit to PF00072, Response regulator receiver domain, score 4.4e-39
862962009422	PS00217 Sugar transport proteins signature 2.
862962009423	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.9e-20
862962009424	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
862962009425	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
862962009426	dimerization interface [polypeptide binding]; other site
862962009427	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962009428	dimer interface [polypeptide binding]; other site
862962009429	phosphorylation site [posttranslational modification]
862962009430	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009431	ATP binding site [chemical binding]; other site
862962009432	Mg2+ binding site [ion binding]; other site
862962009433	G-X-G motif; other site
862962009434	Signal peptide predicted for BF638R2300 by SignalP 2.0 HMM (Signal peptide probability 0.924) with cleavage site probability 0.827 between residues 21 and 22
862962009435	2 probable transmembrane helices predicted for BF638R2300 by TMHMM2.0 at aa 7-29 and 155-177
862962009436	HMMPfam hit to PF00672, HAMP domain, score 9.4e-09
862962009437	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.4e-14
862962009438	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.8e-23
862962009439	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
862962009440	5 probable transmembrane helices predicted for BF638R2301 by TMHMM2.0 at aa 7-29, 49-71, 121-143, 156-178 and 198-220
862962009441	HMMPfam hit to PF01914, MarC family integral membrane protein, score 3.7e-11
862962009442	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_6; cd01844
862962009443	active site
862962009444	catalytic triad [active]
862962009445	oxyanion hole [active]
862962009446	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
862962009447	active site
862962009448	catalytic triad [active]
862962009449	oxyanion hole [active]
862962009450	Signal peptide predicted for BF638R2302 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.638 between residues 24 and 25
862962009451	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009452	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
862962009453	active site
862962009454	SAM binding site [chemical binding]; other site
862962009455	homodimer interface [polypeptide binding]; other site
862962009456	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 1.7e-05
862962009457	PS00839 Uroporphyrin-III C-methyltransferase signature 1.
862962009458	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
862962009459	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
862962009460	putative ligand binding site [chemical binding]; other site
862962009461	Signal peptide predicted for BF638R2304 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.709 between residues 24 and 25
862962009462	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009463	HMMPfam hit to PF01497, Periplasmic binding protein, score 0.00031
862962009464	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
862962009465	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
862962009466	ABC-ATPase subunit  interface; other site
862962009467	dimer interface [polypeptide binding]; other site
862962009468	putative PBP binding regions; other site
862962009469	Signal peptide predicted for BF638R2305 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.254 between residues 27 and 28
862962009470	8 probable transmembrane helices predicted for BF638R2305 by TMHMM2.0 at aa 5-27, 87-109, 124-146, 153-175, 203-225, 246-268, 288-307 and 314-336
862962009471	HMMPfam hit to PF01032, FecCD transport family, score 4.8e-63
862962009472	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
862962009473	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
862962009474	Walker A/P-loop; other site
862962009475	ATP binding site [chemical binding]; other site
862962009476	Q-loop/lid; other site
862962009477	ABC transporter signature motif; other site
862962009478	Walker B; other site
862962009479	D-loop; other site
862962009480	H-loop/switch region; other site
862962009481	HMMPfam hit to PF00005, ABC transporter, score 1.7e-52
862962009482	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009483	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
862962009484	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
862962009485	NADP binding site [chemical binding]; other site
862962009486	active site
862962009487	putative substrate binding site [chemical binding]; other site
862962009488	HMMPfam hit to PF04321, RmlD substrate binding domain, score 4.3e-20
862962009489	Signal peptide predicted for BF638R2308 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.830 between residues 21 and 22
862962009490	Signal peptide predicted for BF638R2309 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.734 between residues 21 and 22
862962009491	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962009492	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009493	active site
862962009494	phosphorylation site [posttranslational modification]
862962009495	intermolecular recognition site; other site
862962009496	dimerization interface [polypeptide binding]; other site
862962009497	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962009498	DNA binding site [nucleotide binding]
862962009499	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.7e-17
862962009500	PS00079 Multicopper oxidases signature 1.
862962009501	HMMPfam hit to PF00072, Response regulator receiver domain, score 7.3e-30
862962009502	PS00217 Sugar transport proteins signature 2.
862962009503	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009504	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962009505	dimer interface [polypeptide binding]; other site
862962009506	phosphorylation site [posttranslational modification]
862962009507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009508	ATP binding site [chemical binding]; other site
862962009509	Mg2+ binding site [ion binding]; other site
862962009510	G-X-G motif; other site
862962009511	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.2e-30
862962009512	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.3e-13
862962009513	2 probable transmembrane helices predicted for BF638R2311 by TMHMM2.0 at aa 7-29 and 268-290
862962009514	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962009515	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962009516	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962009517	Signal peptide predicted for BF638R2312 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.814 between residues 20 and 21
862962009518	HMMPfam hit to PF00593, TonB dependent receptor, score 4.2e-12
862962009519	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009520	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962009521	dimer interface [polypeptide binding]; other site
862962009522	phosphorylation site [posttranslational modification]
862962009523	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009524	ATP binding site [chemical binding]; other site
862962009525	Mg2+ binding site [ion binding]; other site
862962009526	G-X-G motif; other site
862962009527	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.1e-29
862962009528	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
862962009529	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.4e-14
862962009530	2 probable transmembrane helices predicted for BF638R2313 by TMHMM2.0 at aa 5-24 and 403-425
862962009531	Signal peptide predicted for BF638R2313 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.975 between residues 19 and 20
862962009532	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
862962009533	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
862962009534	Potassium binding sites [ion binding]; other site
862962009535	Cesium cation binding sites [ion binding]; other site
862962009536	HMMPfam hit to PF01268, Formate--tetrahydrofolate ligase, score 3e-264
862962009537	PS00721 Formate--tetrahydrofolate ligase signature 1.
862962009538	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
862962009539	Signal peptide predicted for BF638R2315 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 20 and 21
862962009540	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
862962009541	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
862962009542	dimer interface [polypeptide binding]; other site
862962009543	active site
862962009544	glycine-pyridoxal phosphate binding site [chemical binding]; other site
862962009545	folate binding site [chemical binding]; other site
862962009546	HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 1.5e-238
862962009547	PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
862962009548	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962009549	Signal peptide predicted for BF638R2317 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.952 between residues 27 and 28
862962009550	1 probable transmembrane helix predicted for BF638R2317 by TMHMM2.0 at aa 12-27
862962009551	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
862962009552	HMMPfam hit to PF01613, Flavin reductase like domain, score 3.3e-06
862962009553	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009554	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
862962009555	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
862962009556	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
862962009557	HMMPfam hit to PF02748, Aspartate carbamoyltransferase regulatory ch, score 6.8e-11
862962009558	HMMPfam hit to PF01948, Aspartate carbamoyltransferase regulatory ch, score 2.2e-37
862962009559	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
862962009560	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
862962009561	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
862962009562	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 2.6e-45
862962009563	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 5e-49
862962009564	PS00097 Aspartate and ornithine carbamoyltransferases signature.
862962009565	Membrane protein of unknown function (DUF340); Region: DUF340; pfam03956
862962009566	HMMPfam hit to PF03956, Membrane protein of unknown function (DUF340, score 1.1e-18
862962009567	6 probable transmembrane helices predicted for BF638R2322 by TMHMM2.0 at aa 3-20, 30-49, 62-84, 88-110, 117-136 and 181-203
862962009568	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962009569	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962009570	Signal peptide predicted for BF638R2324 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.643 between residues 20 and 21
862962009571	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009572	Signal peptide predicted for BF638R2326 by SignalP 2.0 HMM (Signal peptide probability 0.896) with cleavage site probability 0.193 between residues 25 and 26
862962009573	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
862962009574	HMMPfam hit to PF04261, Dyp-type peroxidase family, score 7.5e-106
862962009575	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962009576	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962009577	SusD family; Region: SusD; pfam07980
862962009578	Signal peptide predicted for BF638R2329 by SignalP 2.0 HMM (Signal peptide probability 0.798) with cleavage site probability 0.406 between residues 28 and 29
862962009579	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009580	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962009581	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962009582	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962009583	HMMPfam hit to PF00593, TonB dependent receptor, score 5.4e-14
862962009584	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
862962009585	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2e-23
862962009586	Signal peptide predicted for BF638R2330 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.760 between residues 37 and 38
862962009587	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962009588	Signal peptide predicted for BF638R2331 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 58 and 59
862962009589	1 probable transmembrane helix predicted for BF638R2331 by TMHMM2.0 at aa 42-64
862962009590	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.66
862962009591	AAA domain; Region: AAA_14; pfam13173
862962009592	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
862962009593	catalytic core [active]
862962009594	Signal peptide predicted for BF638R2332 by SignalP 2.0 HMM (Signal peptide probability 0.762) with cleavage site probability 0.318 between residues 27 and 28
862962009595	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 0.002
862962009596	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009597	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
862962009598	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
862962009599	Ligand binding site; other site
862962009600	oligomer interface; other site
862962009601	HMMPfam hit to PF02348, Cytidylyltransferase, score 4.1e-34
862962009602	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962009603	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
862962009604	Transglycosylase; Region: Transgly; pfam00912
862962009605	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
862962009606	Signal peptide predicted for BF638R2336 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.451 between residues 35 and 36
862962009607	1 probable transmembrane helix predicted for BF638R2336 by TMHMM2.0 at aa 20-42
862962009608	HMMPfam hit to PF00912, Transglycosylase, score 2.4e-72
862962009609	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 8.4e-26
862962009610	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009611	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cl00233
862962009612	catalytic center binding site [active]
862962009613	ATP binding site [chemical binding]; other site
862962009614	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962009615	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
862962009616	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962009617	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 0.011
862962009618	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 1.3e-31
862962009619	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962009620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
862962009621	MORN repeat; Region: MORN; cl14787
862962009622	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
862962009623	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
862962009624	MORN repeat; Region: MORN; cl14787
862962009625	Signal peptide predicted for BF638R2339 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.993 between residues 31 and 32
862962009626	HMMPfam hit to PF02493, MORN repeat, score 0.0018
862962009627	HMMPfam hit to PF07661, no description, score 8.6
862962009628	HMMPfam hit to PF02493, MORN repeat, score 7.4e-09
862962009629	HMMPfam hit to PF02493, MORN repeat, score 7e-05
862962009630	HMMPfam hit to PF02493, MORN repeat, score 4.4e-05
862962009631	HMMPfam hit to PF07661, no description, score 19
862962009632	HMMPfam hit to PF02493, MORN repeat, score 6e-09
862962009633	HMMPfam hit to PF02493, MORN repeat, score 4.4e-08
862962009634	HMMPfam hit to PF02493, MORN repeat, score 1.5e-06
862962009635	HMMPfam hit to PF02493, MORN repeat, score 0.00016
862962009636	HMMPfam hit to PF02493, MORN repeat, score 5.8e-05
862962009637	HMMPfam hit to PF07661, no description, score 13
862962009638	HMMPfam hit to PF02493, MORN repeat, score 1.1e-07
862962009639	HMMPfam hit to PF02493, MORN repeat, score 6.5e-10
862962009640	HMMPfam hit to PF07661, no description, score 94
862962009641	HMMPfam hit to PF02493, MORN repeat, score 3.5e-08
862962009642	HMMPfam hit to PF02493, MORN repeat, score 0.00024
862962009643	HMMPfam hit to PF02493, MORN repeat, score 0.024
862962009644	HMMPfam hit to PF07661, no description, score 2.6
862962009645	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
862962009646	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
862962009647	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962009648	active site
862962009649	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.5e-22
862962009650	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
862962009651	PS00114 Phosphoribosyl pyrophosphate synthetase signature.
862962009652	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962009653	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009654	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009655	ATP binding site [chemical binding]; other site
862962009656	Mg2+ binding site [ion binding]; other site
862962009657	G-X-G motif; other site
862962009658	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962009659	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
862962009660	Signal peptide predicted for BF638R2341 by SignalP 2.0 HMM (Signal peptide probability 0.951) with cleavage site probability 0.465 between residues 27 and 28
862962009661	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009662	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009663	2 probable transmembrane helices predicted for BF638R2341 by TMHMM2.0 at aa 442-464 and 1054-1076
862962009664	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.8e-16
862962009665	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009666	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962009667	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009668	active site
862962009669	phosphorylation site [posttranslational modification]
862962009670	intermolecular recognition site; other site
862962009671	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-06
862962009672	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
862962009673	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
862962009674	Signal peptide predicted for BF638R2343 by SignalP 2.0 HMM (Signal peptide probability 0.733) with cleavage site probability 0.352 between residues 33 and 34
862962009675	HMMPfam hit to PF03806, AbgT putative transporter family, score 1.1e-115
862962009676	11 probable transmembrane helices predicted for BF638R2343 by TMHMM2.0 at aa 21-43, 74-96, 116-138, 153-175, 254-276, 291-313, 334-356, 371-393, 400-416, 431-448 and 468-490
862962009677	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962009678	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009679	TPR repeat; Region: TPR_11; pfam13414
862962009680	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962009681	binding surface
862962009682	TPR motif; other site
862962009683	Signal peptide predicted for BF638R2344 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.977 between residues 19 and 20
862962009684	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.3
862962009685	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.33
862962009686	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009687	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.2
862962009688	para-aminobenzoate synthase component I; Validated; Region: PRK07093
862962009689	HMMPfam hit to PF00425, chorismate binding enzyme, score 1.1e-17
862962009690	hypothetical protein; Provisional; Region: PRK07101
862962009691	substrate-cofactor binding pocket; other site
862962009692	TIGR02453 family protein; Region: TIGR02453
862962009693	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
862962009694	N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme); Region: E_set_GBE_euk_N; cd02854
862962009695	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
862962009696	active site
862962009697	catalytic site [active]
862962009698	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
862962009699	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 2.2e-10
862962009700	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 2.1e-09
862962009701	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_3; cd11349
862962009702	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
862962009703	active site
862962009704	catalytic site [active]
862962009705	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 3.2e-12
862962009706	putative oxidoreductase; Provisional; Region: PRK11579
862962009707	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962009708	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
862962009709	HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 5.4e-11
862962009710	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 5.8e-22
862962009711	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
862962009712	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
862962009713	active site
862962009714	nucleophile elbow; other site
862962009715	HMMPfam hit to PF01734, Patatin-like phospholipase, score 1.5e-37
862962009716	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962009717	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962009718	putative substrate translocation pore; other site
862962009719	12 probable transmembrane helices predicted for BF638R2352 by TMHMM2.0 at aa 12-34, 49-66, 79-101, 105-122, 142-164, 169-191, 219-238, 258-280, 287-304, 308-330, 342-364 and 374-393
862962009720	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.7e-43
862962009721	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
862962009722	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
862962009723	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
862962009724	HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 1.2e-38
862962009725	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009726	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962009727	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
862962009728	ligand binding site [chemical binding]; other site
862962009729	flexible hinge region; other site
862962009730	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 0.0012
862962009731	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
862962009732	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962009733	NAD(P) binding site [chemical binding]; other site
862962009734	active site
862962009735	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.2e-10
862962009736	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
862962009737	active site
862962009738	Signal peptide predicted for BF638R2356 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.750 between residues 27 and 28
862962009739	5 probable transmembrane helices predicted for BF638R2356 by TMHMM2.0 at aa 7-25, 50-67, 80-102, 134-151 and 158-180
862962009740	HMMPfam hit to PF01569, PAP2 superfamily, score 2e-10
862962009741	Protein of unknown function (DUF2582); Region: DUF2582; pfam10771
862962009742	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
862962009743	CoA binding domain; Region: CoA_binding; smart00881
862962009744	CoA-ligase; Region: Ligase_CoA; pfam00549
862962009745	HMMPfam hit to PF00549, CoA-ligase, score 5.4e-43
862962009746	PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site.
862962009747	PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1.
862962009748	HMMPfam hit to PF02629, CoA binding domain, score 1.9e-56
862962009749	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
862962009750	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
862962009751	CoA-ligase; Region: Ligase_CoA; pfam00549
862962009752	HMMPfam hit to PF00549, CoA-ligase, score 3.4e-44
862962009753	PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3.
862962009754	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962009755	HMMPfam hit to PF02222, ATP-grasp domain, score 1.1e-15
862962009756	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
862962009757	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
862962009758	HMMPfam hit to PF00698, Acyl transferase domain, score 8.5e-13
862962009759	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
862962009760	dimer interface [polypeptide binding]; other site
862962009761	substrate binding site [chemical binding]; other site
862962009762	ATP binding site [chemical binding]; other site
862962009763	NUDIX domain; Region: NUDIX; pfam00293
862962009764	nudix motif; other site
862962009765	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
862962009766	HMMPfam hit to PF00293, NUDIX domain, score 8.3e-07
862962009767	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
862962009768	D-xylulose kinases, subgroup 2; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_2; cd07810
862962009769	putative N- and C-terminal domain interface [polypeptide binding]; other site
862962009770	putative active site [active]
862962009771	putative MgATP binding site [chemical binding]; other site
862962009772	catalytic site [active]
862962009773	metal binding site [ion binding]; metal-binding site
862962009774	putative xylulose binding site [chemical binding]; other site
862962009775	putative homodimer interface [polypeptide binding]; other site
862962009776	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 1.5e-49
862962009777	HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 1.7e-11
862962009778	xylose isomerase; Provisional; Region: PRK05474
862962009779	xylose isomerase; Region: xylose_isom_A; TIGR02630
862962009780	HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 4e-15
862962009781	PS00172 Xylose isomerase signature 1.
862962009782	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
862962009783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962009784	putative substrate translocation pore; other site
862962009785	12 probable transmembrane helices predicted for BF638R2368 by TMHMM2.0 at aa 13-35, 55-77, 90-109, 124-146, 158-180, 210-232, 280-302, 322-344, 351-369, 384-403, 416-438 and 443-465
862962009786	HMMPfam hit to PF00083, Sugar (and other) transporter, score 4.7e-126
862962009787	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.2e-14
862962009788	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009789	PS00217 Sugar transport proteins signature 2.
862962009790	PS00216 Sugar transport proteins signature 1.
862962009791	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
862962009792	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
862962009793	HMMPfam hit to PF01663, Type I phosphodiesterase / nucleotide py, score 1e-67
862962009794	1 probable transmembrane helix predicted for BF638R2370 by TMHMM2.0 at aa 13-30
862962009795	Signal peptide predicted for BF638R2370 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.836 between residues 29 and 30
862962009796	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962009797	Coenzyme A binding pocket [chemical binding]; other site
862962009798	Predicted amidohydrolase [General function prediction only]; Region: COG0388
862962009799	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
862962009800	putative active site [active]
862962009801	catalytic triad [active]
862962009802	putative dimer interface [polypeptide binding]; other site
862962009803	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00015
862962009804	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 6.4e-19
862962009805	PS01227 Uncharacterized protein family UPF0012 signature.
862962009806	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
862962009807	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
862962009808	dimer interface [polypeptide binding]; other site
862962009809	decamer (pentamer of dimers) interface [polypeptide binding]; other site
862962009810	catalytic triad [active]
862962009811	peroxidatic and resolving cysteines [active]
862962009812	HMMPfam hit to PF00578, AhpC/TSA family, score 5.7e-58
862962009813	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
862962009814	HMMPfam hit to PF00076, RNA recognition motif. (a.k.a. RRM, RBD, or, score 2.6e-24
862962009815	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962009816	Haem-binding domain; Region: Haem_bd; pfam14376
862962009817	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
862962009818	PS00190 Cytochrome c family heme-binding site signature.
862962009819	HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 1e-82
862962009820	PS00190 Cytochrome c family heme-binding site signature.
862962009821	PS00190 Cytochrome c family heme-binding site signature.
862962009822	1 probable transmembrane helix predicted for BF638R2374 by TMHMM2.0 at aa 7-25
862962009823	Signal peptide predicted for BF638R2374 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.308 between residues 19 and 20
862962009824	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
862962009825	7 probable transmembrane helices predicted for BF638R2375 by TMHMM2.0 at aa 7-25, 35-57, 70-87, 131-153, 166-185, 200-217 and 226-248
862962009826	HMMPfam hit to PF01578, Cytochrome C assembly protein, score 6.5e-25
862962009827	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009828	Signal peptide predicted for BF638R2375 by SignalP 2.0 HMM (Signal peptide probability 0.934) with cleavage site probability 0.645 between residues 35 and 36
862962009829	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
862962009830	6 probable transmembrane helices predicted for BF638R2376 by TMHMM2.0 at aa 5-22, 26-48, 68-87, 107-129, 142-161 and 265-284
862962009831	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009832	Signal peptide predicted for BF638R2376 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.631 between residues 21 and 22
862962009833	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962009834	Active site serine [active]
862962009835	Signal peptide predicted for BF638R2377 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.986 between residues 22 and 23
862962009836	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009837	HMMPfam hit to PF03572, Peptidase family S41, score 1.4e-06
862962009838	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
862962009839	10 probable transmembrane helices predicted for BF638R2378 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 105-127, 156-175, 185-207, 228-245, 255-277, 290-309 and 319-341
862962009840	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009841	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009842	Signal peptide predicted for BF638R2378 by SignalP 2.0 HMM (Signal peptide probability 0.957) with cleavage site probability 0.456 between residues 31 and 32
862962009843	isoleucyl-tRNA synthetase; Region: ileS; TIGR00392
862962009844	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962009845	active site
862962009846	HIGH motif; other site
862962009847	nucleotide binding site [chemical binding]; other site
862962009848	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962009849	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962009850	active site
862962009851	KMSKS motif; other site
862962009852	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
862962009853	tRNA binding surface [nucleotide binding]; other site
862962009854	anticodon binding site; other site
862962009855	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 2.9e-168
862962009856	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
862962009857	lipoprotein signal peptidase; Provisional; Region: PRK14788
862962009858	lipoprotein signal peptidase; Provisional; Region: PRK14787
862962009859	4 probable transmembrane helices predicted for BF638R2381 by TMHMM2.0 at aa 12-29, 61-83, 96-118 and 171-193
862962009860	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
862962009861	Signal peptide predicted for BF638R2382 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.843 between residues 21 and 22
862962009862	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009863	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
862962009864	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
862962009865	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
862962009866	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 2.7e-08
862962009867	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
862962009868	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
862962009869	Signal peptide predicted for BF638R2385 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.474 between residues 33 and 34
862962009870	1 probable transmembrane helix predicted for BF638R2385 by TMHMM2.0 at aa 15-32
862962009871	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 0.00022
862962009872	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962009873	Signal peptide predicted for BF638R2386 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.384 between residues 24 and 25
862962009874	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009875	HMMPfam hit to PF01103, Surface antigen, score 4.8e-55
862962009876	Domain of unknown function (DUF3332); Region: DUF3332; pfam11810
862962009877	2 probable transmembrane helices predicted for BF638R2387 by TMHMM2.0 at aa 20-42 and 62-84
862962009878	Signal peptide predicted for BF638R2387 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.224 between residues 45 and 46
862962009879	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009880	DoxX; Region: DoxX; pfam07681
862962009881	4 probable transmembrane helices predicted for BF638R2388 by TMHMM2.0 at aa 13-35, 55-77, 79-101 and 111-133
862962009882	HMMPfam hit to PF07681, DoxX, score 1.6e-23
862962009883	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
862962009884	Signal peptide predicted for BF638R2390 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.663 between residues 23 and 24
862962009885	HMMPfam hit to PF07396, Phosphate-selective porin O and P, score 1.8e-26
862962009886	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009887	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962009888	H+ Antiporter protein; Region: 2A0121; TIGR00900
862962009889	putative substrate translocation pore; other site
862962009890	10 probable transmembrane helices predicted for BF638R2391 by TMHMM2.0 at aa 11-33, 43-65, 72-94, 166-188, 216-238, 253-275, 282-304, 309-331, 343-365 and 370-392
862962009891	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.9e-32
862962009892	Signal peptide predicted for BF638R2391 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.343 between residues 49 and 50
862962009893	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
862962009894	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2.9e-15
862962009895	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962009896	putative substrate translocation pore; other site
862962009897	12 probable transmembrane helices predicted for BF638R2393 by TMHMM2.0 at aa 30-47, 52-74, 83-105, 125-144, 165-184, 194-216, 236-258, 282-299, 306-328, 338-360, 381-403 and 428-450
862962009898	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6e-16
862962009899	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009900	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
862962009901	glucuronate isomerase; Reviewed; Region: PRK02925
862962009902	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
862962009903	HMMPfam hit to PF02614, Glucuronate isomerase, score 1.4e-237
862962009904	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
862962009905	HMMPfam hit to PF00498, FHA domain, score 1.9e-09
862962009906	Sporulation related domain; Region: SPOR; pfam05036
862962009907	1 probable transmembrane helix predicted for BF638R2396 by TMHMM2.0 at aa 168-190
862962009908	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009909	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
862962009910	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 6.8e-91
862962009911	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
862962009912	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
862962009913	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
862962009914	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 1.3e-94
862962009915	Signal peptide predicted for BF638R2398 by SignalP 2.0 HMM (Signal peptide probability 0.772) with cleavage site probability 0.767 between residues 20 and 21
862962009916	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 2.2e-51
862962009917	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 1.3e-36
862962009918	Signal peptide predicted for BF638R2399 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.621 between residues 28 and 29
862962009919	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009920	helicase 45; Provisional; Region: PTZ00424
862962009921	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
862962009922	ATP binding site [chemical binding]; other site
862962009923	Mg++ binding site [ion binding]; other site
862962009924	motif III; other site
862962009925	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962009926	nucleotide binding region [chemical binding]; other site
862962009927	ATP-binding site [chemical binding]; other site
862962009928	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.6e-32
862962009929	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.4e-62
862962009930	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
862962009931	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009932	CT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_1; cd04870
862962009933	ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_2; cd04871
862962009934	phosphoserine phosphatase SerB; Region: serB; TIGR00338
862962009935	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962009936	motif II; other site
862962009937	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.9e-28
862962009938	HMMPfam hit to PF01842, ACT domain, score 0.0033
862962009939	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962009940	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962009941	catalytic residues [active]
862962009942	Signal peptide predicted for BF638R2402 by SignalP 2.0 HMM (Signal peptide probability 0.897) with cleavage site probability 0.498 between residues 22 and 23
862962009943	Predicted permeases [General function prediction only]; Region: COG0795
862962009944	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
862962009945	HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 6.7e-44
862962009946	6 probable transmembrane helices predicted for BF638R2403 by TMHMM2.0 at aa 13-35, 63-85, 106-128, 284-301, 308-330 and 343-360
862962009947	Signal peptide predicted for BF638R2403 by SignalP 2.0 HMM (Signal peptide probability 0.898) with cleavage site probability 0.536 between residues 35 and 36
862962009948	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
862962009949	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
862962009950	HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase, score 3.5e-108
862962009951	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962009952	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
862962009953	Found in ATP-dependent protease La (LON); Region: LON; smart00464
862962009954	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962009955	Walker A motif; other site
862962009956	ATP binding site [chemical binding]; other site
862962009957	Walker B motif; other site
862962009958	arginine finger; other site
862962009959	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
862962009960	HMMPfam hit to PF05362, Lon protease (S16) C-terminal proteolytic do, score 1.3e-112
862962009961	PS01046 ATP-dependent serine proteases, lon family, serine active site.
862962009962	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 6.4e-47
862962009963	PS00017 ATP/GTP-binding site motif A (P-loop).
862962009964	HMMPfam hit to PF02190, ATP-dependent protease La (LON) domain, score 1.6e-10
862962009965	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
862962009966	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962009967	S-adenosylmethionine binding site [chemical binding]; other site
862962009968	PS00092 N-6 Adenine-specific DNA methylases signature.
862962009969	Protein of unknown function (DUF1622); Region: DUF1622; pfam07784
862962009970	3 probable transmembrane helices predicted for BF638R2407 by TMHMM2.0 at aa 10-32, 52-69 and 84-101
862962009971	HMMPfam hit to PF07784, Protein of unknown function (DUF1622), score 4.6e-35
862962009972	PAS domain; Region: PAS; smart00091
862962009973	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
862962009974	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962009975	ATP binding site [chemical binding]; other site
862962009976	Mg2+ binding site [ion binding]; other site
862962009977	G-X-G motif; other site
862962009978	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1e-35
862962009979	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0049
862962009980	2 probable transmembrane helices predicted for BF638R2408 by TMHMM2.0 at aa 7-26 and 30-51
862962009981	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962009982	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962009983	active site
862962009984	phosphorylation site [posttranslational modification]
862962009985	intermolecular recognition site; other site
862962009986	dimerization interface [polypeptide binding]; other site
862962009987	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962009988	Walker A motif; other site
862962009989	ATP binding site [chemical binding]; other site
862962009990	Walker B motif; other site
862962009991	arginine finger; other site
862962009992	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962009993	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.9e-13
862962009994	PS00688 Sigma-54 interaction domain C-terminal part signature.
862962009995	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 2.1e-137
862962009996	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-24
862962009997	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962009998	Signal peptide predicted for BF638R2410 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 20 and 21
862962009999	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.2e-05
862962010000	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962010001	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962010002	1 probable transmembrane helix predicted for BF638R2411 by TMHMM2.0 at aa 12-34
862962010003	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010004	FtsX-like permease family; Region: FtsX; pfam02687
862962010005	FtsX-like permease family; Region: FtsX; pfam02687
862962010006	Signal peptide predicted for BF638R2412 by SignalP 2.0 HMM (Signal peptide probability 0.764) with cleavage site probability 0.643 between residues 51 and 52
862962010007	8 probable transmembrane helices predicted for BF638R2412 by TMHMM2.0 at aa 27-49, 279-301, 332-354, 369-391, 412-434, 694-716, 746-765 and 780-802
862962010008	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010009	HMMPfam hit to PF02687, Predicted permease, score 0.0012
862962010010	HMMPfam hit to PF02687, Predicted permease, score 9.2e-08
862962010011	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010012	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
862962010013	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010014	FtsX-like permease family; Region: FtsX; pfam02687
862962010015	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010016	FtsX-like permease family; Region: FtsX; pfam02687
862962010017	Signal peptide predicted for BF638R2413 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.802 between residues 37 and 38
862962010018	8 probable transmembrane helices predicted for BF638R2413 by TMHMM2.0 at aa 21-43, 270-292, 313-335, 360-382, 402-424, 654-676, 710-732 and 742-764
862962010019	HMMPfam hit to PF02687, Predicted permease, score 0.0012
862962010020	HMMPfam hit to PF02687, Predicted permease, score 4.9e-18
862962010021	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010022	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010023	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010024	FtsX-like permease family; Region: FtsX; pfam02687
862962010025	Signal peptide predicted for BF638R2414 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.763 between residues 37 and 38
862962010026	8 probable transmembrane helices predicted for BF638R2414 by TMHMM2.0 at aa 21-43, 266-288, 313-335, 359-381, 402-424, 652-674, 694-716 and 736-758
862962010027	HMMPfam hit to PF02687, Predicted permease, score 0.00022
862962010028	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010029	HMMPfam hit to PF02687, Predicted permease, score 3.5e-16
862962010030	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010031	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010032	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010033	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010034	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962010035	FtsX-like permease family; Region: FtsX; pfam02687
862962010036	8 probable transmembrane helices predicted for BF638R2415 by TMHMM2.0 at aa 21-43, 271-293, 320-342, 376-398, 411-433, 677-699, 729-748 and 763-782
862962010037	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010038	HMMPfam hit to PF02687, Predicted permease, score 5.9e-21
862962010039	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010040	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
862962010041	FtsX-like permease family; Region: FtsX; pfam02687
862962010042	8 probable transmembrane helices predicted for BF638R2416 by TMHMM2.0 at aa 21-43, 251-273, 294-316, 352-371, 392-414, 616-638, 670-692 and 707-729
862962010043	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010044	HMMPfam hit to PF02687, Predicted permease, score 0.00026
862962010045	HMMPfam hit to PF02687, Predicted permease, score 0.00028
862962010046	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010047	FtsX-like permease family; Region: FtsX; pfam02687
862962010048	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962010049	8 probable transmembrane helices predicted for BF638R2417 by TMHMM2.0 at aa 22-44, 271-293, 320-342, 367-389, 410-432, 655-677, 698-720 and 735-757
862962010050	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010051	HMMPfam hit to PF02687, Predicted permease, score 1.1e-07
862962010052	HMMPfam hit to PF02687, Predicted permease, score 2.5e-05
862962010053	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962010054	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
862962010055	Walker A/P-loop; other site
862962010056	ATP binding site [chemical binding]; other site
862962010057	Q-loop/lid; other site
862962010058	ABC transporter signature motif; other site
862962010059	Walker B; other site
862962010060	D-loop; other site
862962010061	H-loop/switch region; other site
862962010062	HMMPfam hit to PF00005, ABC transporter, score 3.5e-61
862962010063	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010064	PS00211 ABC transporters family signature.
862962010065	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
862962010066	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
862962010067	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
862962010068	substrate-cofactor binding pocket; other site
862962010069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962010070	catalytic residue [active]
862962010071	HMMPfam hit to PF00155, Aminotransferase class I and II, score 5e-33
862962010072	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962010073	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010074	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
862962010075	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
862962010076	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 2.2e-32
862962010077	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
862962010078	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
862962010079	dimer interface [polypeptide binding]; other site
862962010080	anticodon binding site; other site
862962010081	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
862962010082	homodimer interface [polypeptide binding]; other site
862962010083	motif 1; other site
862962010084	active site
862962010085	motif 2; other site
862962010086	GAD domain; Region: GAD; pfam02938
862962010087	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
862962010088	motif 3; other site
862962010089	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.1e-22
862962010090	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 1.9e-12
862962010091	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962010092	HMMPfam hit to PF02938, GAD domain, score 1.1e-20
862962010093	Predicted membrane protein [Function unknown]; Region: COG2246
862962010094	GtrA-like protein; Region: GtrA; pfam04138
862962010095	4 probable transmembrane helices predicted for BF638R2423 by TMHMM2.0 at aa 7-29, 39-61, 74-93 and 103-120
862962010096	HMMPfam hit to PF04138, GtrA-like protein, score 4.1e-18
862962010097	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
862962010098	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
862962010099	putative active site; other site
862962010100	catalytic triad [active]
862962010101	putative dimer interface [polypeptide binding]; other site
862962010102	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 9.2e-59
862962010103	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
862962010104	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
862962010105	HMMPfam hit to PF04371, Porphyromonas-type peptidyl-arginine deimin, score 5.3e-170
862962010106	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962010107	Uncharacterized protein containing a ferredoxin domain [Function unknown]; Region: COG4739
862962010108	Uncharacterized protein containing a ferredoxin domain (DUF2148); Region: DUF2148; pfam09918
862962010109	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
862962010110	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962010111	Walker A/P-loop; other site
862962010112	ATP binding site [chemical binding]; other site
862962010113	Q-loop/lid; other site
862962010114	ABC transporter signature motif; other site
862962010115	Walker B; other site
862962010116	D-loop; other site
862962010117	H-loop/switch region; other site
862962010118	HMMPfam hit to PF00005, ABC transporter, score 4.3e-29
862962010119	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010120	PS00211 ABC transporters family signature.
862962010121	Uncharacterized protein family (UPF0014); Region: UPF0014; cl00424
862962010122	HMMPfam hit to PF03649, Uncharacterised protein family (UPF0014), score 1.7e-15
862962010123	7 probable transmembrane helices predicted for BF638R2428 by TMHMM2.0 at aa 4-26, 38-60, 65-87, 92-114, 124-146, 189-211 and 221-243
862962010124	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
862962010125	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
862962010126	putative metal binding site [ion binding]; other site
862962010127	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 5e-12
862962010128	Signal peptide predicted for BF638R2431 by SignalP 2.0 HMM (Signal peptide probability 0.757) with cleavage site probability 0.690 between residues 21 and 22
862962010129	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010130	Uncharacterized conserved protein [Function unknown]; Region: COG0327
862962010131	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
862962010132	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
862962010133	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
862962010134	HMMPfam hit to PF01784, NIF3 (NGG1p interacting factor 3), score 4.3e-65
862962010135	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
862962010136	Putative zinc ribbon domain; Region: DUF164; pfam02591
862962010137	HMMPfam hit to PF02591, Uncharacterized ACR, COG1579, score 6.4e-15
862962010138	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962010139	Signal peptide predicted for BF638R2434 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.411 between residues 18 and 19
862962010140	HMMPfam hit to PF02321, Outer membrane efflux protein, score 8.8e-33
862962010141	HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.3e-33
862962010142	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962010143	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962010144	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962010145	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010146	HMMPfam hit to PF00529, HlyD family secretion protein, score 4e-10
862962010147	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962010148	Signal peptide predicted for BF638R2436 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.495 between residues 23 and 24
862962010149	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962010150	12 probable transmembrane helices predicted for BF638R2436 by TMHMM2.0 at aa 12-34, 343-362, 367-389, 393-415, 445-467, 477-499, 531-553, 868-890, 897-919, 923-945, 966-988 and 998-1020
862962010151	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010152	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
862962010153	PS00215 Mitochondrial energy transfer proteins signature.
862962010154	AMP nucleosidase; Provisional; Region: PRK07115
862962010155	HMMPfam hit to PF01048, Phosphorylase family, score 6.4e-11
862962010156	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
862962010157	DNA polymerase III, delta subunit; Region: holA; TIGR01128
862962010158	HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 7e-13
862962010159	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962010160	non-specific DNA binding site [nucleotide binding]; other site
862962010161	salt bridge; other site
862962010162	sequence-specific DNA binding site [nucleotide binding]; other site
862962010163	HMMPfam hit to PF01381, Helix-turn-helix, score 1.1e-10
862962010164	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiB; COG0543
862962010165	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
862962010166	FAD binding pocket [chemical binding]; other site
862962010167	FAD binding motif [chemical binding]; other site
862962010168	phosphate binding motif [ion binding]; other site
862962010169	beta-alpha-beta structure motif; other site
862962010170	NAD binding pocket [chemical binding]; other site
862962010171	Iron coordination center [ion binding]; other site
862962010172	HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 1.4e-08
862962010173	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
862962010174	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
862962010175	heterodimer interface [polypeptide binding]; other site
862962010176	active site
862962010177	FMN binding site [chemical binding]; other site
862962010178	homodimer interface [polypeptide binding]; other site
862962010179	substrate binding site [chemical binding]; other site
862962010180	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 8.2e-85
862962010181	PS00911 Dihydroorotate dehydrogenase signature 1.
862962010182	PS00912 Dihydroorotate dehydrogenase signature 2.
862962010183	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
862962010184	HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase, score 5.4e-106
862962010185	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
862962010186	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
862962010187	nucleotide binding pocket [chemical binding]; other site
862962010188	K-X-D-G motif; other site
862962010189	catalytic site [active]
862962010190	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
862962010191	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
862962010192	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
862962010193	Dimer interface [polypeptide binding]; other site
862962010194	BRCT sequence motif; other site
862962010195	HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 1.1e-146
862962010196	HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 4.7e-37
862962010197	PS01056 NAD-dependent DNA ligase signature 2.
862962010198	HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc fing, score 1.8e-12
862962010199	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.00064
862962010200	HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain, score 1.1e-16
862962010201	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
862962010202	dihydrodipicolinate synthase; Region: dapA; TIGR00674
862962010203	dimer interface [polypeptide binding]; other site
862962010204	active site
862962010205	catalytic residue [active]
862962010206	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 6.4e-95
862962010207	PS00666 Dihydrodipicolinate synthetase signature 2.
862962010208	1 probable transmembrane helix predicted for BF638R2446 by TMHMM2.0 at aa 194-216
862962010209	This hit extended beyond the end of the feature by 1 aa and was clipped.; PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962010211	Protein of unknown function (DUF419); Region: DUF419; pfam04237
862962010212	HMMPfam hit to PF04237, Protein of unknown function (DUF419), score 2.1e-22
862962010213	Uncharacterized conserved protein [Function unknown]; Region: COG1262
862962010214	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
862962010215	Signal peptide predicted for BF638R2449 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.466 between residues 27 and 28
862962010216	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010217	HMMPfam hit to PF03781, Domain of unknown function (DUF323), score 5.1e-43
862962010218	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
862962010219	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
862962010220	active site
862962010221	nucleophile elbow; other site
862962010222	HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.3e-35
862962010223	1 probable transmembrane helix predicted for BF638R2450 by TMHMM2.0 at aa 9-26
862962010224	Signal peptide predicted for BF638R2450 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.981 between residues 25 and 26
862962010225	heat shock protein 90; Provisional; Region: PRK05218
862962010226	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962010227	ATP binding site [chemical binding]; other site
862962010228	Mg2+ binding site [ion binding]; other site
862962010229	G-X-G motif; other site
862962010230	HMMPfam hit to PF00183, Hsp90 protein, score 2e-10
862962010231	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-08
862962010232	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
862962010233	Clp amino terminal domain; Region: Clp_N; pfam02861
862962010234	Clp amino terminal domain; Region: Clp_N; pfam02861
862962010235	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962010236	Walker A motif; other site
862962010237	ATP binding site [chemical binding]; other site
862962010238	Walker B motif; other site
862962010239	arginine finger; other site
862962010240	UvrB/uvrC motif; Region: UVR; pfam02151
862962010241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962010242	Walker A motif; other site
862962010243	ATP binding site [chemical binding]; other site
862962010244	Walker B motif; other site
862962010245	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
862962010246	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 0.00018
862962010247	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.8e-105
862962010248	PS00871 Chaperonins clpA/B signature 2.
862962010249	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010250	HMMPfam hit to PF02151, UvrB/uvrC motif, score 8.3e-07
862962010251	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 2e-12
862962010252	PS00870 Chaperonins clpA/B signature 1.
862962010253	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010254	HMMPfam hit to PF02861, Clp amino terminal domain, score 2.3e-06
862962010255	HMMPfam hit to PF02861, Clp amino terminal domain, score 2.6e-16
862962010256	DNA gyrase subunit A; Validated; Region: PRK05560
862962010257	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
862962010258	CAP-like domain; other site
862962010259	active site
862962010260	primary dimer interface [polypeptide binding]; other site
862962010261	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
862962010262	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
862962010263	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
862962010264	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
862962010265	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
862962010266	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 1.6e-301
862962010267	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.5e-13
862962010268	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 4.8e-12
862962010269	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.1e-11
862962010270	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 4.3e-14
862962010271	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 3.1e-15
862962010272	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 3.6e-12
862962010273	TPR repeat; Region: TPR_11; pfam13414
862962010274	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962010275	binding surface
862962010276	TPR motif; other site
862962010277	Signal peptide predicted for BF638R2454 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 19 and 20
862962010278	HMMPfam hit to PF07720, Tetratricopeptide repeat, score 0.1
862962010279	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.6e-05; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2e-06
862962010280	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
862962010281	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
862962010282	Ligand Binding Site [chemical binding]; other site
862962010283	HMMPfam hit to PF00582, Universal stress protein family, score 3.9e-15
862962010284	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962010285	binding surface
862962010286	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962010287	TPR motif; other site
862962010288	Bacterial SH3 domain homologues; Region: SH3b; smart00287
862962010289	2 probable transmembrane helices predicted for BF638R2457 by TMHMM2.0 at aa 156-178 and 188-205
862962010290	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.3e-09; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 6.4e-08
862962010291	Signal peptide predicted for BF638R2457 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 19 and 20
862962010292	Oxygen tolerance; Region: BatD; pfam13584
862962010293	1 probable transmembrane helix predicted for BF638R2458 by TMHMM2.0 at aa 466-488
862962010294	Signal peptide predicted for BF638R2458 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.964 between residues 28 and 29
862962010295	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962010296	binding surface
862962010297	TPR motif; other site
862962010298	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962010299	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1e-05; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0027
862962010300	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.19; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.047
862962010301	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.47; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3.3
862962010302	Signal peptide predicted for BF638R2459 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.967 between residues 23 and 24
862962010303	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
862962010304	metal ion-dependent adhesion site (MIDAS); other site
862962010305	3 probable transmembrane helices predicted for BF638R2460 by TMHMM2.0 at aa 10-27, 59-78 and 308-325
862962010306	HMMPfam hit to PF00092, von Willebrand factor type A domain, score 9.5e-27
862962010307	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
862962010308	metal ion-dependent adhesion site (MIDAS); other site
862962010309	3 probable transmembrane helices predicted for BF638R2461 by TMHMM2.0 at aa 2-24, 50-72 and 301-323
862962010310	HMMPfam hit to PF00092, von Willebrand factor type A domain, score 3.3e-26
862962010311	Oxygen tolerance; Region: BatD; pfam13584
862962010312	2 probable transmembrane helices predicted for BF638R2462 by TMHMM2.0 at aa 154-176 and 328-350
862962010313	Signal peptide predicted for BF638R2462 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.834 between residues 20 and 21
862962010314	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
862962010315	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
862962010316	metal ion-dependent adhesion site (MIDAS); other site
862962010317	MoxR-like ATPases [General function prediction only]; Region: COG0714
862962010318	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962010319	Walker A motif; other site
862962010320	ATP binding site [chemical binding]; other site
862962010321	Walker B motif; other site
862962010322	arginine finger; other site
862962010323	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 6.8e-08
862962010324	HMMPfam hit to PF07726, ATPase family associated with various cellul, score 6.9e-87
862962010325	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962010326	IHF - DNA interface [nucleotide binding]; other site
862962010327	IHF dimer interface [polypeptide binding]; other site
862962010328	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962010329	1 probable transmembrane helix predicted for BF638R2465 by TMHMM2.0 at aa 305-327
862962010330	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 9.5e-12
862962010331	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962010332	IHF dimer interface [polypeptide binding]; other site
862962010333	IHF - DNA interface [nucleotide binding]; other site
862962010334	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 5.1e-15
862962010335	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
862962010336	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
862962010337	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962010338	FeS/SAM binding site; other site
862962010339	PS00387 Inorganic pyrophosphatase signature.
862962010340	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.1e-27
862962010341	PS01278 Uncharacterized protein family UPF0004 signature.
862962010342	HMMPfam hit to PF00919, Uncharacterized protein family UPF0004, score 5.8e-27
862962010343	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
862962010344	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
862962010345	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
862962010346	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 3.2e-113
862962010347	PS00300 SRP54-type proteins GTP-binding domain signature.
862962010348	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010349	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 4.7e-14
862962010350	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010351	ribosomal protein L33; Region: rpl33; CHL00104
862962010352	HMMPfam hit to PF00471, Ribosomal protein L33, score 2.1e-20
862962010353	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
862962010354	HMMPfam hit to PF00830, Ribosomal L28 family, score 1.2e-19
862962010355	competence damage-inducible protein A; Provisional; Region: PRK00549
862962010356	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
862962010357	putative MPT binding site; other site
862962010358	Competence-damaged protein; Region: CinA; pfam02464
862962010359	HMMPfam hit to PF02464, Competence-damaged protein, score 7e-72
862962010360	HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 9.5e-17
862962010361	UGMP family protein; Validated; Region: PRK09604
862962010362	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
862962010363	HMMPfam hit to PF00814, Glycoprotease family, score 6.2e-23
862962010364	PS01016 Glycoprotease family signature.
862962010365	Family of unknown function (DUF490); Region: DUF490; pfam04357
862962010366	1 probable transmembrane helix predicted for BF638R2474 by TMHMM2.0 at aa 32-54
862962010367	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962010368	hypothetical protein; Provisional; Region: PRK11770
862962010369	Domain of unknown function (DUF307); Region: DUF307; pfam03733
862962010370	Domain of unknown function (DUF307); Region: DUF307; pfam03733
862962010371	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 2e-23
862962010372	4 probable transmembrane helices predicted for BF638R2475 by TMHMM2.0 at aa 7-24, 28-50, 63-82 and 86-103
862962010373	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 2.2e-21
862962010374	prolyl-tRNA synthetase; Provisional; Region: PRK08661
862962010375	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
862962010376	dimer interface [polypeptide binding]; other site
862962010377	motif 1; other site
862962010378	active site
862962010379	motif 2; other site
862962010380	motif 3; other site
862962010381	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
862962010382	anticodon binding site; other site
862962010383	zinc-binding site [ion binding]; other site
862962010384	HMMPfam hit to PF03129, Anticodon binding domain, score 1.7e-23
862962010385	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.4e-26
862962010386	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962010387	TIGR02757 family protein; Region: TIGR02757
862962010388	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
862962010389	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962010390	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962010391	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962010392	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
862962010393	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
862962010394	protein binding site [polypeptide binding]; other site
862962010395	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
862962010396	Domain interface; other site
862962010397	Peptide binding site; other site
862962010398	Active site tetrad [active]
862962010399	HMMPfam hit to PF03572, Peptidase family S41, score 2.9e-24
862962010400	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.048
862962010401	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 9.7
862962010402	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 4.5
862962010403	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.0011
862962010404	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 8
862962010405	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 3
862962010406	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 6.5
862962010407	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 2.2e-06
862962010408	Signal peptide predicted for BF638R2478 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.415 between residues 22 and 23
862962010409	1 probable transmembrane helix predicted for BF638R2478 by TMHMM2.0 at aa 5-22
862962010410	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
862962010411	AAA domain; Region: AAA_18; pfam13238
862962010412	homotrimer interface [polypeptide binding]; other site
862962010413	Walker A motif; other site
862962010414	GTP binding site [chemical binding]; other site
862962010415	Walker B motif; other site
862962010416	HMMPfam hit to PF02283, Cobinamide kinase / cobinamide phosphate gua, score 2.9e-47
862962010417	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010418	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
862962010419	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
862962010420	active site pocket [active]
862962010421	putative dimer interface [polypeptide binding]; other site
862962010422	putative cataytic base [active]
862962010423	HMMPfam hit to PF02277, Phosphoribosyltransferase, score 1.1e-114
862962010424	cobalamin synthase; Reviewed; Region: cobS; PRK00235
862962010425	HMMPfam hit to PF02654, Cobalamin-5-phosphate synthase, score 5.2e-13
862962010426	4 probable transmembrane helices predicted for BF638R2481 by TMHMM2.0 at aa 45-67, 107-129, 194-216 and 229-248
862962010427	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010428	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
862962010429	catalytic core [active]
862962010430	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 5.5e-10
862962010431	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
862962010432	HMMPfam hit to PF03186, CobD/Cbib protein, score 1e-94
862962010433	6 probable transmembrane helices predicted for BF638R2483 by TMHMM2.0 at aa 4-26, 64-86, 90-112, 160-182, 217-236 and 298-320
862962010434	PS00070 Aldehyde dehydrogenases cysteine active site.
862962010435	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
862962010436	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962010437	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962010438	homodimer interface [polypeptide binding]; other site
862962010439	catalytic residue [active]
862962010440	HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.1e-07
862962010441	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
862962010442	cobyric acid synthase; Provisional; Region: PRK00784
862962010443	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
862962010444	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
862962010445	catalytic triad [active]
862962010446	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 4.8e-53
862962010447	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 8.3e-41
862962010448	1 probable transmembrane helix predicted for BF638R2487 by TMHMM2.0 at aa 94-112
862962010449	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010450	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962010451	Signal peptide predicted for BF638R2490 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.692 between residues 25 and 26
862962010452	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.8e-16
862962010453	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962010454	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
862962010455	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962010456	Signal peptide predicted for BF638R2491 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.420 between residues 35 and 36
862962010457	1 probable transmembrane helix predicted for BF638R2491 by TMHMM2.0 at aa 12-34
862962010458	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
862962010459	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962010460	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962010461	6 probable transmembrane helices predicted for BF638R2492 by TMHMM2.0 at aa 36-58, 203-225, 252-274, 284-306, 313-335 and 367-389
862962010462	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962010463	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962010464	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
862962010465	5 probable transmembrane helices predicted for BF638R2493 by TMHMM2.0 at aa 163-185, 223-245, 255-277, 284-306 and 340-362
862962010466	GAF domain; Region: GAF; pfam01590
862962010467	GAF domain; Region: GAF_2; pfam13185
862962010468	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
862962010469	PAS fold; Region: PAS_3; pfam08447
862962010470	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962010471	dimer interface [polypeptide binding]; other site
862962010472	phosphorylation site [posttranslational modification]
862962010473	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962010474	ATP binding site [chemical binding]; other site
862962010475	Mg2+ binding site [ion binding]; other site
862962010476	G-X-G motif; other site
862962010477	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5e-35
862962010478	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.4e-22
862962010479	HMMPfam hit to PF01590, GAF domain, score 7.9e-06
862962010480	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
862962010481	HMMPfam hit to PF01923, Cobalamin adenosyltransferase, score 1e-61
862962010482	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
862962010483	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
862962010484	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
862962010485	catalytic triad [active]
862962010486	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 9.9e-17
862962010487	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.6e-32
862962010488	8 probable transmembrane helices predicted for BF638R2497 by TMHMM2.0 at aa 15-34, 47-64, 74-96, 103-125, 129-151, 156-178, 182-201 and 214-236
862962010489	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
862962010490	4 probable transmembrane helices predicted for BF638R2498 by TMHMM2.0 at aa 10-31, 52-74, 84-106 and 127-149
862962010491	Uncharacterized conserved protein [Function unknown]; Region: COG2966
862962010492	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
862962010493	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
862962010494	4 probable transmembrane helices predicted for BF638R2499 by TMHMM2.0 at aa 149-170, 183-202, 217-239 and 246-263
862962010495	HMMPfam hit to PF06738, Protein of unknown function (DUF1212), score 4.1e-59
862962010496	putative transporter; Validated; Region: PRK03818
862962010497	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962010498	TrkA-C domain; Region: TrkA_C; pfam02080
862962010499	TrkA-C domain; Region: TrkA_C; pfam02080
862962010500	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
862962010501	11 probable transmembrane helices predicted for BF638R2500 by TMHMM2.0 at aa 15-34, 41-63, 78-97, 104-126, 165-187, 384-403, 413-430, 450-472, 476-498, 505-524 and 539-561
862962010502	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 2.2e-61
862962010503	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010504	HMMPfam hit to PF02080, TrkA-C domain, score 1.5e-10
862962010505	HMMPfam hit to PF02080, TrkA-C domain, score 7.3e-12
862962010506	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 8.2e-56
862962010507	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010508	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
862962010509	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962010510	N-terminal plug; other site
862962010511	ligand-binding site [chemical binding]; other site
862962010512	Signal peptide predicted for BF638R2501 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.856 between residues 21 and 22
862962010513	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.8e-21
862962010514	HMMPfam hit to PF00593, TonB dependent receptor, score 3.3e-23
862962010515	Cobalt chelatase (CbiK); Region: CbiK; pfam06180
862962010516	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
862962010517	active site
862962010518	C-terminal domain interface [polypeptide binding]; other site
862962010519	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
862962010520	active site
862962010521	N-terminal domain interface [polypeptide binding]; other site
862962010522	HMMPfam hit to PF06180, Cobalt chelatase (CbiK), score 2e-91
862962010523	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
862962010524	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962010525	N-terminal plug; other site
862962010526	ligand-binding site [chemical binding]; other site
862962010527	Signal peptide predicted for BF638R2503 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.723 between residues 19 and 20
862962010528	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.1e-23
862962010529	HMMPfam hit to PF00593, TonB dependent receptor, score 3e-26
862962010530	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
862962010531	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
862962010532	Signal peptide predicted for BF638R2504 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.916 between residues 43 and 44
862962010533	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.016
862962010534	4 probable transmembrane helices predicted for BF638R2504 by TMHMM2.0 at aa 13-35, 204-226, 247-269 and 458-480
862962010535	HMMPfam hit to PF03929, PepSY-associated TM helix, score 11
862962010536	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010537	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.27
862962010538	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
862962010539	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
862962010540	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
862962010541	Signal peptide predicted for BF638R2505 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.946 between residues 49 and 50
862962010542	2 probable transmembrane helices predicted for BF638R2505 by TMHMM2.0 at aa 13-35 and 1286-1308
862962010543	HMMPfam hit to PF02514, CobN/Magnesium Chelatase, score 9.2e-156
862962010544	6 probable transmembrane helices predicted for BF638R2506 by TMHMM2.0 at aa 4-23, 28-46, 61-83, 103-125, 130-152 and 165-184
862962010545	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
862962010546	Signal peptide predicted for BF638R2507 by SignalP 2.0 HMM (Signal peptide probability 0.826) with cleavage site probability 0.344 between residues 34 and 35
862962010547	3 probable transmembrane helices predicted for BF638R2507 by TMHMM2.0 at aa 15-37, 116-138 and 153-172
862962010548	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 0.0016
862962010549	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
862962010550	1 probable transmembrane helix predicted for BF638R2508 by TMHMM2.0 at aa 15-37
862962010551	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
862962010552	active site
862962010553	SAM binding site [chemical binding]; other site
862962010554	homodimer interface [polypeptide binding]; other site
862962010555	Precorrin-8X methylmutase; Region: CbiC; pfam02570
862962010556	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
862962010557	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 6.8e-41
862962010558	HMMPfam hit to PF02570, Precorrin-8X methylmutase, score 8.1e-43
862962010559	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
862962010560	active site
862962010561	putative homodimer interface [polypeptide binding]; other site
862962010562	SAM binding site [chemical binding]; other site
862962010563	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
862962010564	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962010565	S-adenosylmethionine binding site [chemical binding]; other site
862962010566	PS00678 Trp-Asp (WD) repeats signature.
862962010567	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
862962010568	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
862962010569	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
862962010570	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
862962010571	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
862962010572	active site
862962010573	SAM binding site [chemical binding]; other site
862962010574	homodimer interface [polypeptide binding]; other site
862962010575	HMMPfam hit to PF01890, CbiG, score 2e-47
862962010576	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 4.3e-42
862962010577	PS00840 Uroporphyrin-III C-methyltransferase signature 2.
862962010578	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
862962010579	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; cl00922
862962010580	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
862962010581	HMMPfam hit to PF01888, CbiD, score 3.4e-63
862962010582	Signal peptide predicted for BF638R2513 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.674 between residues 35 and 36
862962010583	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010584	Hexokinase [Carbohydrate transport and metabolism]; Region: COG5026
862962010585	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
862962010586	nucleotide binding site [chemical binding]; other site
862962010587	Hexokinase; Region: Hexokinase_2; pfam03727
862962010588	HMMPfam hit to PF03727, Hexokinase, score 8e-08
862962010589	HMMPfam hit to PF00349, Hexokinase, score 1.8e-11
862962010590	prophago
862962010591	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962010592	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
862962010593	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
862962010594	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962010595	Signal peptide predicted for BF638R2519 by SignalP 2.0 HMM (Signal peptide probability 0.751) with cleavage site probability 0.206 between residues 34 and 35
862962010596	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010597	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010598	1 probable transmembrane helix predicted for BF638R2520 by TMHMM2.0 at aa 12-34
862962010599	Signal peptide predicted for BF638R2520 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.324 between residues 33 and 34
862962010600	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010601	Signal peptide predicted for BF638R2521 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.723 between residues 23 and 24
862962010602	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962010603	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962010604	Signal peptide predicted for BF638R2522 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.516 between residues 25 and 26
862962010605	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010606	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cl17916
862962010607	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010608	Signal peptide predicted for BF638R2523 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.528 between residues 26 and 27
862962010609	1 probable transmembrane helix predicted for BF638R2523 by TMHMM2.0 at aa 7-26
862962010610	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962010611	Signal peptide predicted for BF638R2524 by SignalP 2.0 HMM (Signal peptide probability 0.815) with cleavage site probability 0.712 between residues 24 and 25
862962010612	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010613	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962010614	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962010615	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962010616	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010617	Signal peptide predicted for BF638R2526 by SignalP 2.0 HMM (Signal peptide probability 0.920) with cleavage site probability 0.628 between residues 22 and 23
862962010618	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962010619	Signal peptide predicted for BF638R2527 by SignalP 2.0 HMM (Signal peptide probability 0.944) with cleavage site probability 0.577 between residues 29 and 30
862962010620	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010621	Signal peptide predicted for BF638R2528 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.529 between residues 19 and 20
862962010622	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010623	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010624	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962010625	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
862962010626	active site
862962010627	catalytic residues [active]
862962010628	DNA binding site [nucleotide binding]
862962010629	Int/Topo IB signature motif; other site
862962010630	HMMPfam hit to PF00589, Phage integrase family, score 8.5e-06
862962010631	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
862962010632	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
862962010633	Domain of unknown function (DUF4248); Region: DUF4248; pfam14053
862962010634	replicative DNA helicase; Region: DnaB; TIGR00665
862962010635	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
862962010636	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
862962010637	Walker A motif; other site
862962010638	ATP binding site [chemical binding]; other site
862962010639	Walker B motif; other site
862962010640	DNA binding loops [nucleotide binding]
862962010641	HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 9.5e-34
862962010642	HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 3.9e-65
862962010643	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010644	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
862962010645	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
862962010646	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962010647	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
862962010648	amidase catalytic site [active]
862962010649	Zn binding residues [ion binding]; other site
862962010650	substrate binding site [chemical binding]; other site
862962010651	HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 3.8e-06
862962010652	PS00228 Tubulin-beta mRNA autoregulation signal.
862962010653	PS00018 EF-hand calcium-binding domain.
862962010654	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962010655	non-specific DNA binding site [nucleotide binding]; other site
862962010656	salt bridge; other site
862962010657	sequence-specific DNA binding site [nucleotide binding]; other site
862962010658	HMMPfam hit to PF01381, Helix-turn-helix, score 1.1e-14
862962010659	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
862962010660	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
862962010661	dimer interface [polypeptide binding]; other site
862962010662	active site
862962010663	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
862962010664	catalytic residues [active]
862962010665	substrate binding site [chemical binding]; other site
862962010666	HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 1.4e-05
862962010667	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
862962010668	Part of AAA domain; Region: AAA_19; pfam13245
862962010669	Family description; Region: UvrD_C_2; pfam13538
862962010670	HMMPfam hit to PF00580, UvrD/REP helicase, score 5.8e-185
862962010671	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010672	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
862962010673	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
862962010674	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
862962010675	HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 1e-40
862962010676	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010677	HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 8e-64
862962010678	PS00088 Manganese and iron superoxide dismutases signature.
862962010679	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
862962010680	thiS-thiF/thiG interaction site; other site
862962010681	HMMPfam hit to PF02597, ThiS family, score 1.4e-12
862962010682	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
862962010683	thiamine phosphate binding site [chemical binding]; other site
862962010684	active site
862962010685	pyrophosphate binding site [ion binding]; other site
862962010686	HMMPfam hit to PF02581, Thiamine monophosphate synthase/TENI, score 7.1e-52
862962010687	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
862962010688	ThiS interaction site; other site
862962010689	putative active site [active]
862962010690	tetramer interface [polypeptide binding]; other site
862962010691	HMMPfam hit to PF05690, Thiazole biosynthesis protein ThiG, score 4.4e-157
862962010692	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
862962010693	ThiC-associated domain; Region: ThiC-associated; pfam13667
862962010694	ThiC family; Region: ThiC; pfam01964
862962010695	HMMPfam hit to PF01964, ThiC family, score 1.1e-303
862962010696	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
862962010697	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962010698	FeS/SAM binding site; other site
862962010699	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
862962010700	HMMPfam hit to PF04055, Radical SAM superfamily, score 5.3e-10
862962010701	HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 1.6e-36
862962010702	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
862962010703	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
862962010704	ATP binding site [chemical binding]; other site
862962010705	substrate interface [chemical binding]; other site
862962010706	HMMPfam hit to PF00899, ThiF family, score 2.1e-54
862962010707	1 probable transmembrane helix predicted for BF638R2552 by TMHMM2.0 at aa 26-48
862962010708	HMMPfam hit to PF05237, MoeZ/MoeB domain, score 8.7e-06
862962010709	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
862962010710	thiamine phosphate binding site [chemical binding]; other site
862962010711	active site
862962010712	pyrophosphate binding site [ion binding]; other site
862962010713	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962010714	1 probable transmembrane helix predicted for BF638R2554 by TMHMM2.0 at aa 13-32
862962010715	Signal peptide predicted for BF638R2554 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 28 and 29
862962010716	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962010717	Signal peptide predicted for BF638R2555 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.578 between residues 24 and 25
862962010718	1 probable transmembrane helix predicted for BF638R2555 by TMHMM2.0 at aa 5-24
862962010719	prophage
862962010720	Signal peptide predicted for BF638R2557 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.800 between residues 22 and 23
862962010721	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
862962010722	inhibitor binding site; inhibition site
862962010723	catalytic motif [active]
862962010724	Catalytic residue [active]
862962010725	Active site flap [active]
862962010726	PS00141 Eukaryotic and viral aspartyl proteases active site.
862962010727	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010728	Domain of unknown function, B. Theta Gene description (DUF3871); Region: DUF3871; pfam12987
862962010729	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
862962010730	Signal peptide predicted for BF638R2561 by SignalP 2.0 HMM (Signal peptide probability 0.810) with cleavage site probability 0.498 between residues 34 and 35
862962010731	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010732	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
862962010733	active site
862962010734	catalytic residues [active]
862962010735	DNA binding site [nucleotide binding]
862962010736	Int/Topo IB signature motif; other site
862962010737	pyruvate phosphate dikinase; Provisional; Region: PRK09279
862962010738	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
862962010739	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
862962010740	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
862962010741	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
862962010742	HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 3.7e-161
862962010743	PS00742 PEP-utilizing enzymes signature 2.
862962010744	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 2.4e-45
862962010745	PS00370 PEP-utilizing enzymes phosphorylation site signature.
862962010746	HMMPfam hit to PF01326, Pyruvate phosphate dikinase, PEP/pyru, score 2.6e-155
862962010747	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
862962010748	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962010749	S-adenosylmethionine binding site [chemical binding]; other site
862962010750	HMMPfam hit to PF01938, TRAM domain, score 5.1e-07
862962010751	HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 3.8e-06
862962010752	PS01230 RNA methyltransferase trmA family signature 1.
862962010753	PS01231 RNA methyltransferase trmA family signature 2.
862962010754	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
862962010755	RNA binding surface [nucleotide binding]; other site
862962010756	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
862962010757	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
862962010758	active site
862962010759	HMMPfam hit to PF01479, S4 domain, score 0.018
862962010760	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 7.1e-25
862962010761	PS01129 Rlu family of pseudouridine synthase signature.
862962010762	Signal peptide predicted for BF638R2568 by SignalP 2.0 HMM (Signal peptide probability 0.837) with cleavage site probability 0.547 between residues 21 and 22
862962010763	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010764	Signal peptide predicted for BF638R2569 by SignalP 2.0 HMM (Signal peptide probability 0.792) with cleavage site probability 0.656 between residues 26 and 27
862962010765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010766	methionine aminopeptidase; Provisional; Region: PRK12318
862962010767	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
862962010768	active site
862962010769	HMMPfam hit to PF00557, metallopeptidase family M24, score 5.5e-75
862962010770	RmuC family; Region: RmuC; pfam02646
862962010771	Signal peptide predicted for BF638R2571 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.438 between residues 29 and 30
862962010772	HMMPfam hit to PF00672, no description, score 0.83
862962010773	1 probable transmembrane helix predicted for BF638R2571 by TMHMM2.0 at aa 5-22
862962010774	HMMPfam hit to PF02646, RmuC family, score 7.7e-113
862962010775	Uncharacterized ArCR, COG2043; Region: DUF169; cl00894
862962010776	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
862962010777	11 probable transmembrane helices predicted for BF638R2573 by TMHMM2.0 at aa 19-41, 61-83, 102-124, 134-153, 160-182, 187-205, 214-236, 306-328, 335-357, 377-399 and 412-434
862962010778	HMMPfam hit to PF06965, Na+/H+ antiporter, score 3.8e-151
862962010779	Signal peptide predicted for BF638R2573 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.610 between residues 32 and 33
862962010780	12 probable transmembrane helices predicted for BF638R2574 by TMHMM2.0 at aa 5-24, 28-50, 70-92, 107-129, 141-162, 166-183, 195-214, 224-241, 254-276, 299-321, 333-355 and 360-382
862962010781	PS00334 Myb DNA-binding domain repeat signature 2.
862962010782	Signal peptide predicted for BF638R2574 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.968 between residues 25 and 26
862962010783	GTP-binding protein LepA; Provisional; Region: PRK05433
862962010784	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
862962010785	G1 box; other site
862962010786	putative GEF interaction site [polypeptide binding]; other site
862962010787	GTP/Mg2+ binding site [chemical binding]; other site
862962010788	Switch I region; other site
862962010789	G2 box; other site
862962010790	G3 box; other site
862962010791	Switch II region; other site
862962010792	G4 box; other site
862962010793	G5 box; other site
862962010794	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
862962010795	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
862962010796	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
862962010797	HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 1.9e-84
862962010798	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 7e-34
862962010799	HMMPfam hit to PF03144, Elongation factor Tu domain, score 4.4e-11
862962010800	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7.6e-68
862962010801	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010802	Protein of unknown function (DUF2582); Region: DUF2582; pfam10771
862962010803	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
862962010804	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
862962010805	HMMPfam hit to PF01894, Uncharacterised protein family UPF0047, score 6.2e-48
862962010806	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
862962010807	putative active site [active]
862962010808	putative catalytic site [active]
862962010809	putative DNA binding site [nucleotide binding]; other site
862962010810	putative phosphate binding site [ion binding]; other site
862962010811	metal binding site A [ion binding]; metal-binding site
862962010812	putative AP binding site [nucleotide binding]; other site
862962010813	putative metal binding site B [ion binding]; other site
862962010814	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.9e-49
862962010815	PS00726 AP endonucleases family 1 signature 1.
862962010816	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
862962010817	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
862962010818	11 probable transmembrane helices predicted for BF638R2580 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 130-152, 159-181, 196-218, 246-268, 292-323, 336-353, 359-381 and 394-416
862962010819	HMMPfam hit to PF01566, Natural resistance-associated macrophage pro, score 5.9e-50
862962010820	Signal peptide predicted for BF638R2581 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.667 between residues 42 and 43
862962010821	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010822	TSCPD domain; Region: TSCPD; cl14834
862962010823	hypothetical protein; Provisional; Region: PRK12378
862962010824	HMMPfam hit to PF01709, Domain of unknown function DUF28, score 1.3e-95
862962010825	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
862962010826	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
862962010827	putative tRNA-binding site [nucleotide binding]; other site
862962010828	B3/4 domain; Region: B3_4; pfam03483
862962010829	tRNA synthetase B5 domain; Region: B5; smart00874
862962010830	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
862962010831	dimer interface [polypeptide binding]; other site
862962010832	motif 1; other site
862962010833	motif 3; other site
862962010834	motif 2; other site
862962010835	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
862962010836	HMMPfam hit to PF03147, Ferredoxin-fold anticodon binding domain, score 5.4e-31
862962010837	HMMPfam hit to PF03484, tRNA synthetase B5 domain, score 3.1e-19
862962010838	HMMPfam hit to PF03483, B3/4 domain, score 1.4e-93
862962010839	HMMPfam hit to PF01588, Putative tRNA binding domain, score 1.3e-28
862962010840	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
862962010841	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
862962010842	Mg++ binding site [ion binding]; other site
862962010843	putative catalytic motif [active]
862962010844	putative substrate binding site [chemical binding]; other site
862962010845	similar to PS_1/PS_E lipopolysaccharide biosynthesis locus in BF9343
862962010846	11 probable transmembrane helices predicted for BF638R2585 by TMHMM2.0 at aa 4-21, 41-58, 62-79, 91-108, 112-131, 138-160, 164-181, 188-210, 215-237, 258-280 and 284-306
862962010847	HMMPfam hit to PF00953, Glycosyl transferase, score 1e-07
862962010848	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962010849	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962010850	NAD(P) binding site [chemical binding]; other site
862962010851	active site
862962010852	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010853	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962010854	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
862962010855	metal-binding site
862962010856	HMMPfam hit to PF00535, Glycosyl transferase, score 4.2e-34
862962010857	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962010858	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
862962010859	HMMPfam hit to PF00534, Glycosyl transferases group, score 7.1e-25
862962010860	11 probable transmembrane helices predicted for BF638R2589 by TMHMM2.0 at aa 4-23, 36-58, 68-90, 121-143, 163-182, 189-220, 230-249, 270-292, 341-363, 370-389 and 394-416
862962010861	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962010862	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
862962010863	putative ADP-binding pocket [chemical binding]; other site
862962010864	HMMPfam hit to PF00534, Glycosyl transferases group, score 3.2e-31
862962010865	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962010866	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
862962010867	10 probable transmembrane helices predicted for BF638R2591 by TMHMM2.0 at aa 12-34, 38-60, 77-99, 109-131, 144-161, 165-187, 287-309, 372-391, 412-431 and 435-457
862962010868	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 4e-23
862962010869	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962010870	active site
862962010871	HMMPfam hit to PF00535, Glycosyl transferase, score 4.4e-15
862962010872	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
862962010873	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
862962010874	PYR/PP interface [polypeptide binding]; other site
862962010875	dimer interface [polypeptide binding]; other site
862962010876	TPP binding site [chemical binding]; other site
862962010877	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
862962010878	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
862962010879	TPP-binding site [chemical binding]; other site
862962010880	PS00187 Thiamine pyrophosphate enzymes signature.
862962010881	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010882	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 1.1e-14
862962010883	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 1.1e-57
862962010884	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962010885	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962010886	NAD(P) binding site [chemical binding]; other site
862962010887	active site
862962010888	Signal peptide predicted for BF638R2595 by SignalP 2.0 HMM (Signal peptide probability 0.950) with cleavage site probability 0.861 between residues 19 and 20
862962010889	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
862962010890	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
862962010891	NAD binding site [chemical binding]; other site
862962010892	homotetramer interface [polypeptide binding]; other site
862962010893	homodimer interface [polypeptide binding]; other site
862962010894	substrate binding site [chemical binding]; other site
862962010895	active site
862962010896	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 1.7e-12
862962010897	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962010898	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
862962010899	substrate binding site; other site
862962010900	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.4e-10
862962010901	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
862962010902	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962010903	inhibitor-cofactor binding pocket; inhibition site
862962010904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962010905	catalytic residue [active]
862962010906	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.4e-122
862962010907	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962010908	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 3.6e-65
862962010909	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962010910	Transcription antiterminator [Transcription]; Region: NusG; COG0250
862962010911	bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional; Region: fkp; PRK13412
862962010912	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
862962010913	HMMPfam hit to PF00288, GHMP kinases putative ATP-binding protei, score 2.4e-18
862962010914	HMMPfam hit to PF07959, L-fucokinase, score 3.5e-137
862962010915	Domain of unknown function (DUF718); Region: DUF718; pfam05336
862962010916	replicative DNA helicase; Region: DnaB; TIGR00665
862962010917	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
862962010918	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
862962010919	Walker A motif; other site
862962010920	ATP binding site [chemical binding]; other site
862962010921	Walker B motif; other site
862962010922	DNA binding loops [nucleotide binding]
862962010923	HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 6.2e-112
862962010924	PS00017 ATP/GTP-binding site motif A (P-loop).
862962010925	HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 4.7e-41
862962010926	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
862962010927	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
862962010928	HMMPfam hit to PF00288, GHMP kinases putative ATP-binding protei, score 2.1e-21
862962010929	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962010930	Signal peptide predicted for BF638R2605 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.480 between residues 23 and 24
862962010931	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010932	Signal peptide predicted for BF638R2606 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.423 between residues 21 and 22
862962010933	PS00443 Glutamine amidotransferases class-II active site.
862962010934	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010935	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962010936	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
862962010937	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
862962010938	NAD binding site [chemical binding]; other site
862962010939	homodimer interface [polypeptide binding]; other site
862962010940	active site
862962010941	substrate binding site [chemical binding]; other site
862962010942	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 4.7e-128
862962010943	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
862962010944	HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 1.6e-81
862962010945	6 probable transmembrane helices predicted for BF638R2608 by TMHMM2.0 at aa 5-24, 39-58, 65-87, 102-124, 131-153 and 168-189
862962010946	electron transport complex RsxE subunit; Provisional; Region: PRK12405
862962010947	5 probable transmembrane helices predicted for BF638R2609 by TMHMM2.0 at aa 33-55, 68-85, 89-111, 124-146 and 166-188
862962010948	HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 3.4e-72
862962010949	Signal peptide predicted for BF638R2609 by SignalP 2.0 HMM (Signal peptide probability 0.688) with cleavage site probability 0.245 between residues 34 and 35
862962010950	FMN-binding domain; Region: FMN_bind; cl01081
862962010951	HMMPfam hit to PF04205, FMN-binding domain, score 9.4e-20
862962010952	1 probable transmembrane helix predicted for BF638R2610 by TMHMM2.0 at aa 20-42
862962010953	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
862962010954	HMMPfam hit to PF03116, NQR2, RnfD, RnfE family, score 2.2e-102
862962010955	8 probable transmembrane helices predicted for BF638R2611 by TMHMM2.0 at aa 26-48, 97-119, 126-148, 188-210, 217-239, 249-271, 278-297 and 301-320
862962010956	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962010957	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
862962010958	SLBB domain; Region: SLBB; pfam10531
862962010959	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
862962010960	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962010961	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962010962	HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase, score 4.1e-36
862962010963	ferredoxin; Validated; Region: PRK07118
862962010964	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
862962010965	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
862962010966	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 1.9e-06
862962010967	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962010968	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00037
862962010969	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962010970	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 6.9e-08
862962010971	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962010972	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.014
862962010973	HMMPfam hit to PF04060, Putative Fe-S cluster, score 2.9e-06
862962010974	1 probable transmembrane helix predicted for BF638R2613 by TMHMM2.0 at aa 4-26
862962010975	Signal peptide predicted for BF638R2613 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.835 between residues 19 and 20
862962010976	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
862962010977	HMMPfam hit to PF04246, Positive regulator of sigma(E), RseC/MucC, score 0.0022
862962010978	2 probable transmembrane helices predicted for BF638R2614 by TMHMM2.0 at aa 76-98 and 102-121
862962010979	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
862962010980	Signal peptide predicted for BF638R2616 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 21 and 22
862962010981	CTP synthetase; Validated; Region: pyrG; PRK05380
862962010982	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
862962010983	Catalytic site [active]
862962010984	active site
862962010985	UTP binding site [chemical binding]; other site
862962010986	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
862962010987	active site
862962010988	putative oxyanion hole; other site
862962010989	catalytic triad [active]
862962010990	HMMPfam hit to PF06418, CTP synthase N-terminus, score 4.3e-200
862962010991	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 5.4e-64
862962010992	PS00442 Glutamine amidotransferases class-I active site.
862962010993	membrane protein insertase; Provisional; Region: PRK01318
862962010994	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
862962010995	Signal peptide predicted for BF638R2619 by SignalP 2.0 HMM (Signal peptide probability 0.840) with cleavage site probability 0.324 between residues 28 and 29
862962010996	6 probable transmembrane helices predicted for BF638R2619 by TMHMM2.0 at aa 5-22, 365-387, 437-459, 479-501, 522-539 and 549-566
862962010997	HMMPfam hit to PF02096, 60Kd inner membrane protein, score 3.4e-48
862962010998	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
862962010999	putative efflux protein, MATE family; Region: matE; TIGR00797
862962011000	12 probable transmembrane helices predicted for BF638R2620 by TMHMM2.0 at aa 12-34, 49-71, 92-114, 129-151, 158-180, 190-212, 239-261, 281-303, 319-341, 351-373, 385-407 and 411-433
862962011001	HMMPfam hit to PF01554, MatE, score 1.3e-27
862962011002	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962011003	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
862962011004	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962011005	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962011006	Signal peptide predicted for BF638R2621 by SignalP 2.0 HMM (Signal peptide probability 0.740) with cleavage site probability 0.360 between residues 38 and 39
862962011007	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011008	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011009	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 8.7
862962011010	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.0019
862962011011	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.42
862962011012	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.12
862962011013	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 9.6
862962011014	HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 1.2e-74
862962011015	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
862962011016	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
862962011017	PspC domain; Region: PspC; pfam04024
862962011018	5 probable transmembrane helices predicted for BF638R2623 by TMHMM2.0 at aa 145-167, 226-248, 250-272, 292-314 and 327-349
862962011019	HMMPfam hit to PF04024, PspC domain, score 1.3e-20
862962011020	Predicted transcriptional regulators [Transcription]; Region: COG1695
862962011021	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
862962011022	HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 8.5e-24
862962011023	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
862962011024	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962011025	Coenzyme A binding pocket [chemical binding]; other site
862962011026	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.1e-10
862962011027	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962011028	putative substrate translocation pore; other site
862962011029	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962011030	14 probable transmembrane helices predicted for BF638R2626 by TMHMM2.0 at aa 21-43, 48-65, 70-92, 102-121, 142-161, 226-248, 281-298, 322-344, 353-372, 387-406, 419-441, 461-483, 496-518 and 523-545
862962011031	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-09
862962011032	HMMPfam hit to PF00854, POT family, score 1e-09
862962011033	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
862962011034	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011035	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
862962011036	putative deacylase active site [active]
862962011037	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 5.7e-51
862962011038	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
862962011039	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
862962011040	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
862962011041	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
862962011042	HMMPfam hit to PF00005, ABC transporter, score 3.4e-25
862962011043	PS00211 ABC transporters family signature.
862962011044	PS00190 Cytochrome c family heme-binding site signature.
862962011045	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011046	PS00211 ABC transporters family signature.
862962011047	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011048	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962011049	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962011050	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
862962011051	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962011052	Signal peptide predicted for BF638R2629 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.979 between residues 24 and 25
862962011053	HMMPfam hit to PF01476, LysM domain, score 4.4e-11
862962011054	HMMPfam hit to PF01476, LysM domain, score 3.5e-12
862962011055	HMMPfam hit to PF01476, LysM domain, score 2e-08
862962011056	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962011057	Signal peptide predicted for BF638R2630 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 25 and 26
862962011058	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
862962011059	4 probable transmembrane helices predicted for BF638R2631 by TMHMM2.0 at aa 7-29, 49-71, 84-103 and 113-132
862962011060	Signal peptide predicted for BF638R2631 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.598 between residues 30 and 31
862962011061	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
862962011062	HMMPfam hit to PF07719, no description, score 1.5
862962011063	HMMPfam hit to PF07719, no description, score 3.3
862962011064	Signal peptide predicted for BF638R2633 by SignalP 2.0 HMM (Signal peptide probability 0.939) with cleavage site probability 0.401 between residues 22 and 23
862962011065	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011066	ACT domain-containing protein [General function prediction only]; Region: COG4747
862962011067	N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains; Region: ACT_Bt0572_1; cd04908
862962011068	C-terminal ACT domain of a novel protein composed of just two ACT domains; Region: ACT_Bt0572_2; cd04882
862962011069	HMMPfam hit to PF01842, ACT domain, score 0.093
862962011070	HMMPfam hit to PF01842, ACT domain, score 0.00061
862962011071	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
862962011072	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962011073	acyl-activating enzyme (AAE) consensus motif; other site
862962011074	AMP binding site [chemical binding]; other site
862962011075	active site
862962011076	CoA binding site [chemical binding]; other site
862962011077	excinuclease ABC subunit B; Provisional; Region: PRK05298
862962011078	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962011079	ATP binding site [chemical binding]; other site
862962011080	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962011081	nucleotide binding region [chemical binding]; other site
862962011082	ATP-binding site [chemical binding]; other site
862962011083	Ultra-violet resistance protein B; Region: UvrB; pfam12344
862962011084	UvrB/uvrC motif; Region: UVR; pfam02151
862962011085	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011086	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2e-17
862962011087	HMMPfam hit to PF02151, UvrB/uvrC motif, score 0.00019
862962011088	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
862962011089	putative active site [active]
862962011090	1 probable transmembrane helix predicted for BF638R2637 by TMHMM2.0 at aa 34-53
862962011091	HMMPfam hit to PF02698, DUF218 domain, score 1.8e-34
862962011092	Signal peptide predicted for BF638R2638 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 34 and 35
862962011093	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
862962011094	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
862962011095	HMMPfam hit to PF01841, Transglutaminase-like superfamily, score 5.3e-14
862962011096	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
862962011097	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
862962011098	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
862962011099	putative dimer interface [polypeptide binding]; other site
862962011100	HMMPfam hit to PF00011, Hsp20/alpha crystallin family, score 1.9e-27
862962011101	PAS domain; Region: PAS_9; pfam13426
862962011102	PAS fold; Region: PAS_4; pfam08448
862962011103	PAS fold; Region: PAS_3; pfam08447
862962011104	PAS fold; Region: PAS_4; pfam08448
862962011105	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962011106	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962011107	dimer interface [polypeptide binding]; other site
862962011108	phosphorylation site [posttranslational modification]
862962011109	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962011110	ATP binding site [chemical binding]; other site
862962011111	Mg2+ binding site [ion binding]; other site
862962011112	G-X-G motif; other site
862962011113	Response regulator receiver domain; Region: Response_reg; pfam00072
862962011114	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962011115	active site
862962011116	phosphorylation site [posttranslational modification]
862962011117	intermolecular recognition site; other site
862962011118	dimerization interface [polypeptide binding]; other site
862962011119	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.7e-34
862962011120	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.9e-34
862962011121	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.4e-23
862962011122	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962011123	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
862962011124	6 probable transmembrane helices predicted for BF638R2642 by TMHMM2.0 at aa 17-39, 180-202, 231-253, 257-279, 291-313 and 343-365
862962011125	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962011126	HMMPfam hit to PF01061, ABC-2 type transporter, score 6.2e-18
862962011127	Signal peptide predicted for BF638R2642 by SignalP 2.0 HMM (Signal peptide probability 0.774) with cleavage site probability 0.502 between residues 37 and 38
862962011128	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
862962011129	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
862962011130	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
862962011131	6 probable transmembrane helices predicted for BF638R2643 by TMHMM2.0 at aa 21-40, 173-195, 214-236, 251-273, 280-302 and 337-359
862962011132	HMMPfam hit to PF01061, ABC-2 type transporter, score 1.7e-28
862962011133	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
862962011134	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
862962011135	Walker A/P-loop; other site
862962011136	ATP binding site [chemical binding]; other site
862962011137	Q-loop/lid; other site
862962011138	ABC transporter signature motif; other site
862962011139	Walker B; other site
862962011140	D-loop; other site
862962011141	H-loop/switch region; other site
862962011142	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
862962011143	Walker A/P-loop; other site
862962011144	ATP binding site [chemical binding]; other site
862962011145	Q-loop/lid; other site
862962011146	ABC transporter signature motif; other site
862962011147	Walker B; other site
862962011148	D-loop; other site
862962011149	H-loop/switch region; other site
862962011150	HMMPfam hit to PF00005, ABC transporter, score 9.7e-47
862962011151	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011152	HMMPfam hit to PF00005, ABC transporter, score 1.4e-52
862962011153	PS00211 ABC transporters family signature.
862962011154	PS00141 Eukaryotic and viral aspartyl proteases active site.
862962011155	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011156	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962011157	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962011158	Signal peptide predicted for BF638R2645 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.455 between residues 24 and 25
862962011159	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011160	Outer membrane efflux protein; Region: OEP; pfam02321
862962011161	Outer membrane efflux protein; Region: OEP; pfam02321
862962011162	HMMPfam hit to PF02321, Outer membrane efflux protein, score 4e-11
862962011163	Signal peptide predicted for BF638R2646 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.527 between residues 34 and 35
862962011164	1 probable transmembrane helix predicted for BF638R2646 by TMHMM2.0 at aa 13-32
862962011165	Signal peptide predicted for BF638R2647 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.380 between residues 21 and 22
862962011166	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011167	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962011168	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962011169	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.1
862962011170	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.2e-07
862962011171	carbamoyl-phosphate synthase, large subunit; Region: CPSaseII_lrg; TIGR01369
862962011172	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962011173	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
862962011174	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
862962011175	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962011176	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962011177	Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain; Region: MGS_CPS_I_III; cd01423
862962011178	probable substrate binding site [chemical binding]; other site
862962011179	HMMPfam hit to PF02142, MGS-like domain, score 3.6e-30
862962011180	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.1e-13
862962011181	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962011182	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
862962011183	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 2e-14
862962011184	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 2.5e-66
862962011185	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 7.6e-142
862962011186	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962011187	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
862962011188	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 8e-58
862962011189	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
862962011190	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
862962011191	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
862962011192	catalytic site [active]
862962011193	subunit interface [polypeptide binding]; other site
862962011194	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 3.6e-68
862962011195	PS00442 Glutamine amidotransferases class-I active site.
862962011196	HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small ch, score 1e-81
862962011197	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011198	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
862962011199	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
862962011200	active site
862962011201	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962011202	active site
862962011203	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
862962011204	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.4e-05
862962011206	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 0.0021
862962011207	PS00443 Glutamine amidotransferases class-II active site.
862962011208	asparagine synthetase B; Provisional; Region: asnB; PRK09431
862962011209	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
862962011210	active site
862962011211	dimer interface [polypeptide binding]; other site
862962011212	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
862962011213	Ligand Binding Site [chemical binding]; other site
862962011214	Molecular Tunnel; other site
862962011215	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.3e-15
862962011216	HMMPfam hit to PF00733, Asparagine synthase, score 8.3e-106
862962011217	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
862962011218	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
862962011219	active site
862962011220	catalytic site [active]
862962011221	Signal peptide predicted for BF638R2654 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.899 between residues 30 and 31
862962011222	HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 1.6e-07
862962011223	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
862962011224	catalytic motif [active]
862962011225	Catalytic residue [active]
862962011226	Aspartyl protease; Region: Asp_protease_2; pfam13650
862962011227	Signal peptide predicted for BF638R2655 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.719 between residues 18 and 19
862962011228	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011229	Prophage
862962011230	Transposase, Mutator family; Region: Transposase_mut; pfam00872
862962011231	MULE transposase domain; Region: MULE; pfam10551
862962011232	HMMPfam hit to PF00872, Transposase, Mutator family, score 1.4e-115
862962011233	PS01007 Transposases, Mutator family, signature.
862962011234	2 probable transmembrane helices predicted for BF638R2657 by TMHMM2.0 at aa 19-41 and 51-73
862962011235	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
862962011236	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011237	PS00019 Actinin-type actin-binding domain signature 1.
862962011238	Signal peptide predicted for BF638R2658 by SignalP 2.0 HMM (Signal peptide probability 0.879) with cleavage site probability 0.869 between residues 18 and 19
862962011239	Signal peptide predicted for BF638R2659 by SignalP 2.0 HMM (Signal peptide probability 0.824) with cleavage site probability 0.545 between residues 22 and 23
862962011240	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011241	dihydrolipoamide dehydrogenase; Validated; Region: acoL; PRK06912
862962011243	1 probable transmembrane helix predicted for BF638R2664 by TMHMM2.0 at aa 44-66
862962011244	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962011245	Int/Topo IB signature motif; other site
862962011246	HMMPfam hit to PF00589, Phage integrase family, score 4.1e-08
862962011247	2 probable transmembrane helices predicted for BF638R2668 by TMHMM2.0 at aa 4-26 and 47-66
862962011248	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962011249	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962011250	Signal peptide predicted for BF638R2669 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 19 and 20
862962011251	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
862962011252	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
862962011253	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
862962011254	HMMPfam hit to PF01678, Diaminopimelate epimerase, score 2.3e-36
862962011255	PS01326 Diaminopimelate epimerase signature.
862962011256	HMMPfam hit to PF01678, Diaminopimelate epimerase, score 1.8e-47
862962011257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011258	L,L-diaminopimelate aminotransferase; Validated; Region: PRK07590
862962011259	Mth938-like domain. The members of this family include: Mth938, 2P1, Xcr35, Rpa2829, and several uncharacterized sequences. Mth938 is a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. This protein crystallizes as a...; Region: Mth938-like; cl00182
862962011260	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962011261	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962011262	homodimer interface [polypeptide binding]; other site
862962011263	catalytic residue [active]
862962011264	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
862962011265	6 probable transmembrane helices predicted for BF638R2672 by TMHMM2.0 at aa 7-24, 29-51, 64-81, 85-107, 114-136 and 146-168
862962011266	Signal peptide predicted for BF638R2672 by SignalP 2.0 HMM (Signal peptide probability 0.720) with cleavage site probability 0.408 between residues 28 and 29
862962011267	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
862962011268	polyphosphate kinase 1; Region: poly_P_kin; TIGR03705
862962011269	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
862962011270	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
862962011271	domain interface [polypeptide binding]; other site
862962011272	active site
862962011273	catalytic site [active]
862962011274	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
862962011275	domain interface [polypeptide binding]; other site
862962011276	active site
862962011277	catalytic site [active]
862962011278	HMMPfam hit to PF02503, Polyphosphate kinase, score 3e-203
862962011279	exopolyphosphatase; Region: exo_poly_only; TIGR03706
862962011280	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
862962011281	HMMPfam hit to PF02541, Ppx/GppA phosphatase family, score 7.9e-23
862962011282	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
862962011283	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
862962011284	dimer interface [polypeptide binding]; other site
862962011285	active site
862962011286	metal binding site [ion binding]; metal-binding site
862962011287	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 4.7e-42
862962011288	PS00060 Iron-containing alcohol dehydrogenases signature 2.
862962011289	PS00913 Iron-containing alcohol dehydrogenases signature 1.
862962011290	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962011291	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
862962011292	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
862962011293	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962011294	catalytic residue [active]
862962011295	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.9e-110
862962011296	PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site.
862962011297	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
862962011298	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
862962011299	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
862962011300	HMMPfam hit to PF04715, Anthranilate synthase component I, N, score 1.2e-06
862962011301	HMMPfam hit to PF00425, chorismate binding enzyme, score 3e-109
862962011302	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
862962011303	Glutamine amidotransferase class-I; Region: GATase; pfam00117
862962011304	glutamine binding [chemical binding]; other site
862962011305	catalytic triad [active]
862962011306	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 6.8e-69
862962011307	PS00442 Glutamine amidotransferases class-I active site.
862962011308	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
862962011309	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
862962011310	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
862962011311	HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 7e-05
862962011312	HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 6.2e-66
862962011313	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
862962011314	active site
862962011315	ribulose/triose binding site [chemical binding]; other site
862962011316	phosphate binding site [ion binding]; other site
862962011317	substrate (anthranilate) binding pocket [chemical binding]; other site
862962011318	product (indole) binding pocket [chemical binding]; other site
862962011319	HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase, score 5.2e-97
862962011320	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
862962011321	active site
862962011322	HMMPfam hit to PF00697, N-(5'phosphoribosyl)anthranilate (PRA) isome, score 2e-27
862962011323	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
862962011324	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
862962011325	substrate binding site [chemical binding]; other site
862962011326	active site
862962011327	catalytic residues [active]
862962011328	heterodimer interface [polypeptide binding]; other site
862962011329	HMMPfam hit to PF00290, Tryptophan synthase alpha chain, score 9.9e-83
862962011330	PS00167 Tryptophan synthase alpha chain signature.
862962011331	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
862962011332	active site
862962011333	homodimer interface [polypeptide binding]; other site
862962011334	PS00144 Asparaginase / glutaminase active site signature 1.
862962011335	HMMPfam hit to PF00710, Asparaginase, score 7.4e-54
862962011336	PS00917 Asparaginase / glutaminase active site signature 2.
862962011337	Signal peptide predicted for BF638R2687 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.732 between residues 23 and 24
862962011338	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011339	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962011340	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962011341	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962011342	active site
862962011343	phosphorylation site [posttranslational modification]
862962011344	intermolecular recognition site; other site
862962011345	dimerization interface [polypeptide binding]; other site
862962011346	HMMPfam hit to PF00072, Response regulator receiver domain, score 2e-22
862962011347	Bacterial sugar transferase; Region: Bac_transf; pfam02397
862962011348	HMMPfam hit to PF02397, Bacterial sugar transferase, score 2.3e-30
862962011349	1 probable transmembrane helix predicted for BF638R2689 by TMHMM2.0 at aa 147-169
862962011350	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
862962011351	Signal peptide predicted for BF638R2690 by SignalP 2.0 HMM (Signal peptide probability 0.784) with cleavage site probability 0.551 between residues 29 and 30
862962011352	3 probable transmembrane helices predicted for BF638R2690 by TMHMM2.0 at aa 10-32, 250-267 and 272-291
862962011353	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
862962011354	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
862962011355	trimer interface [polypeptide binding]; other site
862962011356	active site
862962011357	substrate binding site [chemical binding]; other site
862962011358	CoA binding site [chemical binding]; other site
862962011359	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 51
862962011360	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.7
862962011361	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.004
862962011362	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962011363	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
862962011364	DNA binding residues [nucleotide binding]
862962011365	dimerization interface [polypeptide binding]; other site
862962011366	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.7e-19
862962011367	PS00622 Bacterial regulatory proteins, luxR family signature.
862962011369	HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.00039
862962011370	AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]; Region: PurH; COG0138
862962011371	5-aminoimidazole-4-carboxamide ribonucleotide transformylase; Provisional; Region: PRK07106
862962011372	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 1.8e-87
862962011373	flavodoxin FldA; Validated; Region: PRK09267
862962011374	HMMPfam hit to PF00258, Flavodoxin, score 3.8e-39
862962011375	PS00201 Flavodoxin signature.
862962011376	Protein of unknown function (DUF2023); Region: DUF2023; pfam09633
862962011377	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
862962011378	Signal peptide predicted for BF638R2699 by SignalP 2.0 HMM (Signal peptide probability 0.688) with cleavage site probability 0.332 between residues 46 and 47
862962011379	2 probable transmembrane helices predicted for BF638R2699 by TMHMM2.0 at aa 12-29 and 39-61
862962011380	TQO small subunit DoxD; Region: DoxD; pfam04173
862962011381	TQO small subunit DoxA; Region: DoxA; pfam07680
862962011382	4 probable transmembrane helices predicted for BF638R2700 by TMHMM2.0 at aa 13-35, 81-103, 110-129 and 134-153
862962011383	HMMPfam hit to PF04173, TQO small subunit DoxD, score 5e-91
862962011384	HMMPfam hit to PF07680, TQO small subunit DoxA, score 4.1e-44
862962011385	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962011386	catalytic residues [active]
862962011387	Signal peptide predicted for BF638R2701 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.298 between residues 21 and 22
862962011388	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011389	HMMPfam hit to PF00085, Thioredoxin, score 5.9e-32
862962011390	PS00194 Thioredoxin family active site.
862962011391	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
862962011392	PS00190 Cytochrome c family heme-binding site signature.
862962011393	HMMPfam hit to PF03150, Di-haem cytochrome c peroxidase, score 2.1e-27
862962011394	PS00190 Cytochrome c family heme-binding site signature.
862962011395	Signal peptide predicted for BF638R2702 by SignalP 2.0 HMM (Signal peptide probability 0.925) with cleavage site probability 0.777 between residues 25 and 26
862962011396	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
862962011397	HMMPfam hit to PF01717, Methionine synthase, vitamin-B12 inde, score 0.0033
862962011398	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962011399	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962011400	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962011401	N-terminal plug; other site
862962011402	ligand-binding site [chemical binding]; other site
862962011403	HMMPfam hit to PF00593, TonB dependent receptor, score 5.8e-26
862962011404	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.7e-18
862962011405	Signal peptide predicted for BF638R2704 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23
862962011406	2 probable transmembrane helices predicted for BF638R2705 by TMHMM2.0 at aa 11-33 and 66-88
862962011407	Signal peptide predicted for BF638R2705 by SignalP 2.0 HMM (Signal peptide probability 0.607) with cleavage site probability 0.382 between residues 35 and 36
862962011408	Predicted membrane protein [Function unknown]; Region: COG2311
862962011409	Protein of unknown function (DUF418); Region: DUF418; pfam04235
862962011410	HMMPfam hit to PF04235, Protein of unknown function (DUF418), score 5.1e-12
862962011411	10 probable transmembrane helices predicted for BF638R2707 by TMHMM2.0 at aa 20-37, 57-79, 99-118, 122-136, 143-162, 209-231, 244-263, 283-305, 325-347 and 351-370
862962011412	HMMPfam hit to PF04171, Protein of unknown function (DUF405), score 1.1e-13
862962011413	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
862962011414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962011415	putative substrate translocation pore; other site
862962011416	14 probable transmembrane helices predicted for BF638R2708 by TMHMM2.0 at aa 9-31, 46-68, 77-98, 102-124, 136-158, 163-185, 192-214, 229-251, 272-294, 299-321, 333-355, 365-387, 400-419 and 487-504
862962011417	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.9e-65
862962011418	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
862962011419	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962011420	carboxyltransferase (CT) interaction site; other site
862962011421	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962011422	1 probable transmembrane helix predicted for BF638R2709 by TMHMM2.0 at aa 15-34
862962011423	putative transporter; Validated; Region: PRK03818
862962011424	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962011425	TrkA-C domain; Region: TrkA_C; pfam02080
862962011426	TrkA-C domain; Region: TrkA_C; pfam02080
862962011427	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962011428	10 probable transmembrane helices predicted for BF638R2710 by TMHMM2.0 at aa 7-26, 30-52, 59-77, 87-109, 116-134, 139-161, 356-378, 388-410, 446-468 and 509-531
862962011429	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 1.6e-65
862962011430	HMMPfam hit to PF02080, TrkA-C domain, score 2.7e-12
862962011431	HMMPfam hit to PF02080, TrkA-C domain, score 1.7e-10
862962011432	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 3.8e-63
862962011433	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011434	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
862962011435	HMMPfam hit to PF01545, Cation efflux family, score 2.7e-77
862962011436	6 probable transmembrane helices predicted for BF638R2711 by TMHMM2.0 at aa 21-43, 53-72, 89-107, 122-144, 157-179 and 183-205
862962011437	MAC/Perforin domain; Region: MACPF; cl02616
862962011438	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011439	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011440	Lipocalin-like domain; Region: Lipocalin_6; pfam13944
862962011441	Signal peptide predicted for BF638R2715 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.620 between residues 25 and 26
862962011442	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011443	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
862962011444	Signal peptide predicted for BF638R2716 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.616 between residues 25 and 26
862962011445	1 probable transmembrane helix predicted for BF638R2716 by TMHMM2.0 at aa 7-29
862962011446	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011447	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962011448	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
862962011449	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962011450	N-terminal plug; other site
862962011451	ligand-binding site [chemical binding]; other site
862962011452	Signal peptide predicted for BF638R2717 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.402 between residues 23 and 24
862962011453	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.9e-20
862962011454	HMMPfam hit to PF00593, TonB dependent receptor, score 2.7e-27
862962011455	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
862962011456	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
862962011457	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
862962011458	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
862962011459	Signal peptide predicted for BF638R2718 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.475 between residues 24 and 25
862962011460	2 probable transmembrane helices predicted for BF638R2718 by TMHMM2.0 at aa 5-27 and 1409-1431
862962011461	HMMPfam hit to PF02514, CobN/Magnesium Chelatase, score 2.9e-175
862962011462	7 probable transmembrane helices predicted for BF638R2719 by TMHMM2.0 at aa 4-18, 25-47, 69-91, 104-126, 136-158, 165-187 and 197-219
862962011463	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
862962011464	3 probable transmembrane helices predicted for BF638R2720 by TMHMM2.0 at aa 15-37, 119-141 and 151-170
862962011465	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
862962011466	1 probable transmembrane helix predicted for BF638R2721 by TMHMM2.0 at aa 15-37
862962011467	ribonucleotide-diphosphate reductase subunit alpha; Provisional; Region: PRK12364
862962011468	ATP cone domain; Region: ATP-cone; pfam03477
862962011469	Class I ribonucleotide reductase; Region: RNR_I; cd01679
862962011470	active site
862962011471	dimer interface [polypeptide binding]; other site
862962011472	catalytic residues [active]
862962011473	effector binding site; other site
862962011474	R2 peptide binding site; other site
862962011475	HMMPfam hit to PF03477, ATP cone domain, score 1.2e-18
862962011476	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 2.8e-24
862962011477	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 2.1e-117
862962011478	PS00089 Ribonucleotide reductase large subunit signature.
862962011479	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
862962011480	dimer interface [polypeptide binding]; other site
862962011481	putative radical transfer pathway; other site
862962011482	diiron center [ion binding]; other site
862962011483	tyrosyl radical; other site
862962011484	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 9.9e-33
862962011485	PS00368 Ribonucleotide reductase small subunit signature.
862962011486	1 probable transmembrane helix predicted for BF638R2723 by TMHMM2.0 at aa 182-201
862962011487	1 probable transmembrane helix predicted for BF638R2724 by TMHMM2.0 at aa 53-75
862962011488	Uncharacterized conserved protein [Function unknown]; Region: COG2966
862962011489	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
862962011490	HMMPfam hit to PF06738, Protein of unknown function (DUF1212), score 5e-46
862962011491	4 probable transmembrane helices predicted for BF638R2725 by TMHMM2.0 at aa 137-159, 166-188, 203-225 and 232-254
862962011492	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
862962011493	5 probable transmembrane helices predicted for BF638R2726 by TMHMM2.0 at aa 6-28, 35-52, 62-84, 91-113 and 135-157
862962011494	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
862962011495	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
862962011496	active site
862962011497	intersubunit interface [polypeptide binding]; other site
862962011498	catalytic residue [active]
862962011499	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 6.2e-14
862962011500	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
862962011501	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
862962011502	substrate binding site [chemical binding]; other site
862962011503	ATP binding site [chemical binding]; other site
862962011504	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 4e-23
862962011505	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
862962011506	DNA binding site [nucleotide binding]
862962011507	domain linker motif; other site
862962011508	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
862962011509	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
862962011510	ligand binding site [chemical binding]; other site
862962011511	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 2.8e-07
862962011512	PS00356 Bacterial regulatory proteins, lacI family signature.
862962011513	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.1
862962011514	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962011515	Coenzyme A binding pocket [chemical binding]; other site
862962011516	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 8.3e-08
862962011517	Predicted transcriptional regulators [Transcription]; Region: COG1733
862962011518	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
862962011519	HMMPfam hit to PF01638, Transcriptional regulator, score 5.6e-36
862962011520	PAS domain S-box; Region: sensory_box; TIGR00229
862962011521	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962011522	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962011523	dimer interface [polypeptide binding]; other site
862962011524	phosphorylation site [posttranslational modification]
862962011525	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962011526	ATP binding site [chemical binding]; other site
862962011527	Mg2+ binding site [ion binding]; other site
862962011528	G-X-G motif; other site
862962011529	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962011530	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962011531	active site
862962011532	phosphorylation site [posttranslational modification]
862962011533	intermolecular recognition site; other site
862962011534	dimerization interface [polypeptide binding]; other site
862962011535	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1e-23
862962011536	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 4.5e-38
862962011537	HMMPfam hit to PF00072, Response regulator receiver domain, score 4.9e-26
862962011538	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962011539	Zn2+ binding site [ion binding]; other site
862962011540	Mg2+ binding site [ion binding]; other site
862962011541	AAA domain; Region: AAA_33; pfam13671
862962011542	RNA ligase; Region: RNA_ligase; pfam09414
862962011543	putative peptide chain release factor H; Region: release_prfH; TIGR03072
862962011544	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
862962011545	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 1.9e-17
862962011546	PS00745 Prokaryotic-type class I peptide chain release factors signature.
862962011547	hypothetical protein; Reviewed; Region: PRK09588
862962011548	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
862962011549	HMMPfam hit to PF01139, Uncharacterized protein family UPF0027, score 1.3e-93
862962011550	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
862962011551	13 probable transmembrane helices predicted for BF638R2738 by TMHMM2.0 at aa 5-27, 48-70, 75-97, 104-126, 136-158, 163-185, 190-212, 233-255, 270-292, 294-316, 326-345, 407-429 and 439-461
862962011552	PS00636 Nt-dnaJ domain signature.
862962011553	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011554	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011555	HMMPfam hit to PF03553, Na+/H+ antiporter family, score 3.8e-35
862962011556	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
862962011557	2 probable transmembrane helices predicted for BF638R2739 by TMHMM2.0 at aa 13-30 and 492-514
862962011558	The C-terminal domain of uncharacterized bacterial proteins; Region: Bvu_2165_C_like; cd12843
862962011559	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011560	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
862962011561	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
862962011562	HMMPfam hit to PF00886, Ribosomal protein S16, score 9e-27
862962011563	Signal peptide predicted for BF638R2742 by SignalP 2.0 HMM (Signal peptide probability 0.913) with cleavage site probability 0.402 between residues 19 and 20
862962011564	Signal peptide predicted for BF638R2743 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.479 between residues 28 and 29
862962011565	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011566	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
862962011567	HMMPfam hit to PF00076, RNA recognition motif. (a.k.a. RRM, RBD, or, score 1.3e-24
862962011568	PS00030 Eukaryotic putative RNA-binding region RNP-1 signature.
862962011569	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
862962011570	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
862962011571	1 probable transmembrane helix predicted for BF638R2745 by TMHMM2.0 at aa 404-426
862962011572	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.1e-05
862962011573	Signal peptide predicted for BF638R2745 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.655 between residues 24 and 25
862962011574	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011575	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
862962011576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
862962011577	dimer interface [polypeptide binding]; other site
862962011578	conserved gate region; other site
862962011579	putative PBP binding loops; other site
862962011580	ABC-ATPase subunit interface; other site
862962011581	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-06
862962011582	6 probable transmembrane helices predicted for BF638R2746 by TMHMM2.0 at aa 9-31, 67-89, 101-123, 133-152, 188-210 and 235-254
862962011583	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962011584	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
862962011585	dimer interface [polypeptide binding]; other site
862962011586	conserved gate region; other site
862962011587	putative PBP binding loops; other site
862962011588	ABC-ATPase subunit interface; other site
862962011589	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.3e-21
862962011590	6 probable transmembrane helices predicted for BF638R2747 by TMHMM2.0 at aa 15-37, 63-85, 100-122, 129-151, 187-209 and 230-252
862962011591	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962011592	Signal peptide predicted for BF638R2747 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.927 between residues 39 and 40
862962011593	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
862962011594	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
862962011595	Walker A/P-loop; other site
862962011596	ATP binding site [chemical binding]; other site
862962011597	Q-loop/lid; other site
862962011598	ABC transporter signature motif; other site
862962011599	Walker B; other site
862962011600	D-loop; other site
862962011601	H-loop/switch region; other site
862962011602	TOBE domain; Region: TOBE_2; pfam08402
862962011603	TOBE domain; Region: TOBE_2; pfam08402
862962011604	HMMPfam hit to PF00005, ABC transporter, score 1.1e-63
862962011605	PS00211 ABC transporters family signature.
862962011606	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011607	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962011608	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962011609	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962011610	catalytic residues [active]
862962011611	Signal peptide predicted for BF638R2749 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.377 between residues 30 and 31
862962011612	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011613	PS00194 Thioredoxin family active site.
862962011614	Signal peptide predicted for BF638R2750 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 22 and 23
862962011615	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
862962011616	putative homodimer interface [polypeptide binding]; other site
862962011617	putative active site pocket [active]
862962011618	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
862962011619	HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 4.3e-06
862962011620	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962011621	Glycogen synthase; Region: Glycogen_syn; pfam05693
862962011622	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962011623	HMMPfam hit to PF05693, Glycogen synthase, score 4.1e-21
862962011624	V-type ATP synthase subunit K; Validated; Region: PRK08344
862962011625	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
862962011626	HMMPfam hit to PF00137, ATP synthase subunit C, score 0.00034
862962011627	4 probable transmembrane helices predicted for BF638R2753 by TMHMM2.0 at aa 5-27, 48-70, 80-102 and 123-145
862962011628	HMMPfam hit to PF00137, ATP synthase subunit C, score 0.00021
862962011629	Signal peptide predicted for BF638R2753 by SignalP 2.0 HMM (Signal peptide probability 0.886) with cleavage site probability 0.593 between residues 26 and 27
862962011630	V-type ATP synthase subunit I; Validated; Region: PRK05771
862962011631	HMMPfam hit to PF01496, V-type ATPase 116kDa subunit family, score 2.6e-16
862962011632	7 probable transmembrane helices predicted for BF638R2754 by TMHMM2.0 at aa 321-343, 364-386, 412-434, 439-461, 466-488, 518-540 and 550-572
862962011633	V-type ATP synthase subunit D; Provisional; Region: PRK02195
862962011634	V-type ATP synthase subunit B; Provisional; Region: PRK02118
862962011635	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
862962011636	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
862962011637	Walker A motif homologous position; other site
862962011638	Walker B motif; other site
862962011639	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 7.4e-60
862962011640	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962011641	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 0.0032
862962011642	V-type ATP synthase subunit A; Provisional; Region: PRK04192
862962011643	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
862962011644	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
862962011645	Walker A motif/ATP binding site; other site
862962011646	Walker B motif; other site
862962011647	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
862962011648	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 5.1e-85
862962011649	PS00152 ATP synthase alpha and beta subunits signature.
862962011650	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011651	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 2.3e-08
862962011652	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
862962011653	V-type ATP synthase subunit E; Provisional; Region: PRK01558
862962011654	Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390
862962011655	HMMPfam hit to PF01991, ATP synthase (E/31 kDa) subunit, score 0.00089
862962011656	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
862962011657	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
862962011658	active site
862962011659	dimer interface [polypeptide binding]; other site
862962011660	HMMPfam hit to PF01979, Amidohydrolase family, score 8.6e-09
862962011661	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962011662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962011663	active site
862962011664	phosphorylation site [posttranslational modification]
862962011665	intermolecular recognition site; other site
862962011666	dimerization interface [polypeptide binding]; other site
862962011667	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962011668	DNA binding site [nucleotide binding]
862962011669	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.3e-43
862962011670	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.1e-12
862962011671	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962011672	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962011673	dimer interface [polypeptide binding]; other site
862962011674	phosphorylation site [posttranslational modification]
862962011675	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962011676	ATP binding site [chemical binding]; other site
862962011677	Mg2+ binding site [ion binding]; other site
862962011678	G-X-G motif; other site
862962011679	Signal peptide predicted for BF638R2762 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.752 between residues 23 and 24
862962011680	2 probable transmembrane helices predicted for BF638R2762 by TMHMM2.0 at aa 7-29 and 138-160
862962011681	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.3e-10
862962011682	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.5e-10
862962011683	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962011684	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962011685	Signal peptide predicted for BF638R2763 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.846 between residues 32 and 33
862962011686	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962011687	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962011688	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962011689	Signal peptide predicted for BF638R2764 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.558 between residues 21 and 22
862962011690	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011691	Clostripain family; Region: Peptidase_C11; pfam03415
862962011692	Signal peptide predicted for BF638R2766 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.608 between residues 23 and 24
862962011693	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
862962011694	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
862962011695	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962011696	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
862962011697	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962011698	DNA binding residues [nucleotide binding]
862962011699	HMMPfam hit to PF04545, Sigma-70, region, score 1.8e-18
862962011700	HMMPfam hit to PF04539, Sigma-70 region, score 7e-16
862962011701	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-21
862962011702	HMMPfam hit to PF00140, Sigma-70 factor, region, score 4e-09
862962011703	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
862962011704	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
862962011705	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
862962011706	protein binding site [polypeptide binding]; other site
862962011707	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
862962011708	protein binding site [polypeptide binding]; other site
862962011709	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.011
862962011710	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 3.3e-09
862962011711	HMMPfam hit to PF00089, Trypsin, score 8.9e-15
862962011712	1 probable transmembrane helix predicted for BF638R2769 by TMHMM2.0 at aa 7-29; 1 probable transmembrane helix predicted for BF638R2770 by TMHMM2.0 at aa 13-35
862962011713	Signal peptide predicted for BF638R2769 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.491 between residues 23 and 24; Signal peptide predicted for BF638R2770 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.491 between residues 29 and 30
862962011714	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
862962011715	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
862962011716	HMMPfam hit to PF01841, Transglutaminase-like superfamily, score 5.7e-14
862962011717	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011718	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
862962011719	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
862962011720	active site
862962011721	HMMPfam hit to PF01188, Mandelate racemase / muconate lactonizing en, score 9e-13
862962011722	HMMPfam hit to PF02746, Mandelate racemase / muconate lactonizing en, score 2.1e-05
862962011723	Bacterial SH3 domain; Region: SH3_4; pfam06347
862962011724	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
862962011725	NlpC/P60 family; Region: NLPC_P60; pfam00877
862962011726	HMMPfam hit to PF00877, NlpC/P60 family, score 1.5e-20
862962011727	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011728	Signal peptide predicted for BF638R2773 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.726 between residues 16 and 17
862962011729	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
862962011730	HMMPfam hit to PF03631, Ribonuclease BN-like family, score 2.9e-38
862962011731	6 probable transmembrane helices predicted for BF638R2774 by TMHMM2.0 at aa 54-76, 118-140, 161-183, 203-222, 229-251 and 266-288
862962011732	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
862962011733	putative FMN binding site [chemical binding]; other site
862962011734	HMMPfam hit to PF00881, Nitroreductase family, score 4.1e-23
862962011735	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
862962011736	Lumazine binding domain; Region: Lum_binding; pfam00677
862962011737	Lumazine binding domain; Region: Lum_binding; pfam00677
862962011738	HMMPfam hit to PF00677, Lumazine binding domain, score 5.2e-15
862962011739	HMMPfam hit to PF00677, Lumazine binding domain, score 1.3e-23
862962011740	PS00693 Riboflavin synthase alpha chain family signature.
862962011741	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
862962011742	PhoU domain; Region: PhoU; pfam01895
862962011743	PhoU domain; Region: PhoU; pfam01895
862962011744	HMMPfam hit to PF01895, PhoU family, score 6.3e-16
862962011745	HMMPfam hit to PF01895, PhoU family, score 1.2e-20
862962011746	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14245
862962011747	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
862962011748	Walker A/P-loop; other site
862962011749	ATP binding site [chemical binding]; other site
862962011750	Q-loop/lid; other site
862962011751	ABC transporter signature motif; other site
862962011752	Walker B; other site
862962011753	D-loop; other site
862962011754	H-loop/switch region; other site
862962011755	HMMPfam hit to PF00005, ABC transporter, score 8.8e-60
862962011756	PS00211 ABC transporters family signature.
862962011757	PS00017 ATP/GTP-binding site motif A (P-loop).
862962011758	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
862962011759	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
862962011760	dimer interface [polypeptide binding]; other site
862962011761	conserved gate region; other site
862962011762	putative PBP binding loops; other site
862962011763	ABC-ATPase subunit interface; other site
862962011764	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.9e-35
862962011765	6 probable transmembrane helices predicted for BF638R2779 by TMHMM2.0 at aa 19-41, 66-88, 109-131, 184-206, 213-232 and 258-280
862962011766	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962011767	PBP superfamily domain; Region: PBP_like_2; cl17296
862962011768	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
862962011769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
862962011770	dimer interface [polypeptide binding]; other site
862962011771	conserved gate region; other site
862962011772	putative PBP binding loops; other site
862962011773	ABC-ATPase subunit interface; other site
862962011774	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.8e-19
862962011775	6 probable transmembrane helices predicted for BF638R2780 by TMHMM2.0 at aa 12-34, 176-198, 218-240, 250-269, 299-321 and 367-389
862962011776	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962011777	PBP superfamily domain; Region: PBP_like_2; cl17296
862962011778	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
862962011779	Signal peptide predicted for BF638R2781 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.852 between residues 33 and 34
862962011780	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.0011
862962011781	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
862962011782	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962011783	active site
862962011784	HIGH motif; other site
862962011785	nucleotide binding site [chemical binding]; other site
862962011786	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962011787	active site
862962011788	KMSKS motif; other site
862962011789	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
862962011790	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), ca, score 3.9e-125
862962011791	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962011792	HMMPfam hit to PF03950, tRNA synthetases class I (E and Q), an, score 1e-66
862962011793	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
862962011794	binding surface
862962011795	TPR motif; other site
862962011796	TPR repeat; Region: TPR_11; pfam13414
862962011797	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962011798	binding surface
862962011799	TPR motif; other site
862962011800	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962011801	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962011802	binding surface
862962011803	TPR motif; other site
862962011804	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962011805	binding surface
862962011806	TPR motif; other site
862962011807	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.5
862962011808	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 8.5e-05; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.041
862962011809	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.36; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.21
862962011810	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.33; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.11
862962011811	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00065; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00022
862962011812	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0056
862962011813	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.016
862962011814	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
862962011815	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
862962011816	4 probable transmembrane helices predicted for BF638R2784 by TMHMM2.0 at aa 13-33, 53-75, 144-166 and 189-206
862962011817	HMMPfam hit to PF00597, DedA family, score 9.3e-13
862962011818	Signal peptide predicted for BF638R2785 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.768 between residues 28 and 29
862962011819	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011820	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
862962011821	dimer interface [polypeptide binding]; other site
862962011822	catalytic triad [active]
862962011823	peroxidatic and resolving cysteines [active]
862962011824	HMMPfam hit to PF00578, AhpC/TSA family, score 6.3e-30
862962011825	PS01265 Tpx family signature.
862962011826	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
862962011827	6 probable transmembrane helices predicted for BF638R2787 by TMHMM2.0 at aa 28-50, 54-76, 85-107, 112-131, 143-162 and 167-189
862962011828	multiple promoter invertase; Provisional; Region: mpi; PRK13413
862962011829	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
862962011830	catalytic residues [active]
862962011831	catalytic nucleophile [active]
862962011832	Presynaptic Site I dimer interface [polypeptide binding]; other site
862962011833	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
862962011834	Synaptic Flat tetramer interface [polypeptide binding]; other site
862962011835	Synaptic Site I dimer interface [polypeptide binding]; other site
862962011836	DNA binding site [nucleotide binding]
862962011837	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
862962011838	DNA-binding interface [nucleotide binding]; DNA binding site
862962011839	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 5.4e-19
862962011840	PS00397 Site-specific recombinases active site.
862962011841	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962011842	active site
862962011843	DNA binding site [nucleotide binding]
862962011844	Int/Topo IB signature motif; other site
862962011845	2 probable transmembrane helices predicted for BF638R2789 by TMHMM2.0 at aa 17-39 and 43-65
862962011846	HMMPfam hit to PF00589, Phage integrase family, score 3.6e-05
862962011847	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
862962011848	Bacterial sugar transferase; Region: Bac_transf; pfam02397
862962011849	Signal peptide predicted for BF638R2790 by SignalP 2.0 HMM (Signal peptide probability 0.618) with cleavage site probability 0.603 between residues 40 and 41
862962011850	5 probable transmembrane helices predicted for BF638R2790 by TMHMM2.0 at aa 13-35, 50-69, 89-106, 110-129 and 281-303
862962011851	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011852	HMMPfam hit to PF02397, Bacterial sugar transferase, score 9.6e-10
862962011853	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
862962011854	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
862962011855	Signal peptide predicted for BF638R2792 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.746 between residues 22 and 23
862962011856	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011857	HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 6.3e-07
862962011858	1 probable transmembrane helix predicted for BF638R2792 by TMHMM2.0 at aa 239-261
862962011859	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
862962011860	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
862962011861	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
862962011862	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
862962011863	HMMPfam hit to PF02706, Chain length determinant protein, score 0.017
862962011864	2 probable transmembrane helices predicted for BF638R2793 by TMHMM2.0 at aa 26-48 and 502-524
862962011865	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
862962011866	amidase catalytic site [active]
862962011867	Zn binding residues [ion binding]; other site
862962011868	substrate binding site [chemical binding]; other site
862962011869	HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 4.2e-13
862962011870	PS00018 EF-hand calcium-binding domain.
862962011871	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962011872	Domain of unknown function (DUF4248); Region: DUF4248; pfam14053
862962011873	VirE N-terminal domain; Region: VirE_N; pfam08800
862962011874	Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942
862962011875	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
862962011876	similar to PS_9/PS_I non-variable operon; lipopolysaccharide biosynthesis locus in BF9343
862962011877	transcriptional activator RfaH; Region: RfaH; TIGR01955
862962011878	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962011879	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
862962011880	heterodimer interface [polypeptide binding]; other site
862962011881	homodimer interface [polypeptide binding]; other site
862962011882	PS00268 Cecropin family signature.
862962011883	HMMPfam hit to PF00467, KOW motif, score 0.00025
862962011884	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962011885	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
862962011886	13 probable transmembrane helices predicted for BF638R2800 by TMHMM2.0 at aa 12-34, 44-66, 86-108, 123-145, 158-180, 185-207, 233-255, 316-338, 351-370, 380-399, 406-425, 440-459 and 466-488
862962011887	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
862962011888	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962011889	active site
862962011890	HMMPfam hit to PF00535, Glycosyl transferase, score 1.2e-36
862962011892	3 probable transmembrane helices predicted for BF638R2804 by TMHMM2.0 at aa 21-43, 58-75 and 88-110
862962011893	5 probable transmembrane helices predicted for BF638R2805 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 120-142 and 154-176
862962011894	12 probable transmembrane helices predicted for BF638R2808 by TMHMM2.0 at aa 7-21, 27-49, 62-81, 91-108, 120-137, 141-158, 163-180, 184-201, 213-235, 318-340, 347-364 and 374-391
862962011895	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962011896	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962011897	HMMPfam hit to PF00534, Glycosyl transferases group, score 4.9e-20
862962011898	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
862962011899	putative trimer interface [polypeptide binding]; other site
862962011900	putative CoA binding site [chemical binding]; other site
862962011901	HMMPfam hit to PF00132, no description, score 13
862962011902	HMMPfam hit to PF00132, no description, score 2.5
862962011903	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
862962011904	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962011905	active site
862962011906	HMMPfam hit to PF00535, Glycosyl transferase, score 4.5e-08
862962011907	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
862962011908	GDP-Fucose binding site [chemical binding]; other site
862962011909	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962011910	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962011911	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.8e-22
862962011912	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962011913	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962011914	HMMPfam hit to PF00534, Glycosyl transferases group, score 2.4e-13
862962011915	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962011916	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962011917	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.9e-36
862962011918	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
862962011919	HMMPfam hit to PF03808, Glycosyl transferase WecB/TagA/CpsF f, score 1.2e-49
862962011920	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962011921	Signal peptide predicted for BF638R2817 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.286 between residues 20 and 21
862962011922	1 probable transmembrane helix predicted for BF638R2817 by TMHMM2.0 at aa 7-29
862962011923	Signal peptide predicted for BF638R2818 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.982 between residues 29 and 30
862962011924	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
862962011925	1 probable transmembrane helix predicted for BF638R2818 by TMHMM2.0 at aa 13-32
862962011926	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962011927	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
862962011928	Signal peptide predicted for BF638R2819 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.981 between residues 31 and 32
862962011929	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962011930	Signal peptide predicted for BF638R2820 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 24 and 25
862962011931	Signal peptide predicted for BF638R2821 by SignalP 2.0 HMM (Signal peptide probability 0.605) with cleavage site probability 0.494 between residues 39 and 40
862962011932	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
862962011933	Signal peptide predicted for BF638R2822 by SignalP 2.0 HMM (Signal peptide probability 0.606) with cleavage site probability 0.493 between residues 36 and 37
862962011934	2 probable transmembrane helices predicted for BF638R2822 by TMHMM2.0 at aa 16-38 and 43-61
862962011935	2 probable transmembrane helices predicted for BF638R2821 by TMHMM2.0 at aa 21-43 and 47-64
862962011936	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
862962011937	GldM N-terminal domain; Region: GldM_N; pfam12081
862962011938	GldM C-terminal domain; Region: GldM_C; pfam12080
862962011939	1 probable transmembrane helix predicted for BF638R2823 by TMHMM2.0 at aa 13-30
862962011940	PS00159 KDPG and KHG aldolases active site.
862962011941	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962011942	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962011943	ligand binding site [chemical binding]; other site
862962011944	Signal peptide predicted for BF638R2824 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.978 between residues 27 and 28
862962011945	PS00061 Short-chain dehydrogenases/reductases family signature.
862962011946	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
862962011947	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
862962011948	Substrate binding site; other site
862962011949	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2e-51
862962011950	PS00237 G-protein coupled receptors signature.
862962011951	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
862962011952	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacet, score 8e-168
862962011953	8 probable transmembrane helices predicted for BF638R2827 by TMHMM2.0 at aa 20-39, 46-68, 102-124, 136-158, 193-215, 246-268, 320-342 and 389-411
862962011954	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
862962011955	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
862962011956	active site
862962011957	catalytic residues [active]
862962011958	metal binding site [ion binding]; metal-binding site
862962011959	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
862962011960	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962011961	carboxyltransferase (CT) interaction site; other site
862962011962	biotinylation site [posttranslational modification]; other site
862962011963	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 4.5e-16
862962011964	PS00188 Biotin-requiring enzymes attachment site.
862962011965	HMMPfam hit to PF00682, HMGL-like, score 2.2e-07
862962011966	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; pfam04277
862962011967	1 probable transmembrane helix predicted for BF638R2829 by TMHMM2.0 at aa 7-29
862962011968	Signal peptide predicted for BF638R2829 by SignalP 2.0 HMM (Signal peptide probability 0.723) with cleavage site probability 0.711 between residues 20 and 21
862962011969	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
862962011970	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
862962011971	active site
862962011972	metal binding site [ion binding]; metal-binding site
862962011973	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
862962011974	HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 9.4e-06
862962011975	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.6e-15
862962011976	PS00761 Signal peptidases I signature 3.
862962011977	Signal peptide predicted for BF638R2830 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.893 between residues 24 and 25
862962011978	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
862962011979	Signal peptide predicted for BF638R2831 by SignalP 2.0 HMM (Signal peptide probability 0.946) with cleavage site probability 0.474 between residues 19 and 20
862962011980	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
862962011981	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
862962011982	catalytic residue [active]
862962011983	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 3.5e-07
862962011984	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
862962011985	Dihydroorotate dehydrogenase (DHOD) like proteins. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD...; Region: DHOD_like; cd04739
862962011986	putative active site [active]
862962011987	putative FMN binding site [chemical binding]; other site
862962011988	putative substrate binding site [chemical binding]; other site
862962011989	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 1.4e-07
862962011990	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
862962011991	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
862962011992	HMMPfam hit to PF01471, Putative peptidoglycan binding domain, score 0.00086
862962011993	Protein of unknown function (DUF2589); Region: DUF2589; pfam11655
862962011994	Protein of unknown function (DUF2589); Region: DUF2589; pfam11655
862962011995	LytTr DNA-binding domain; Region: LytTR; smart00850
862962011996	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 1.3e-09
862962011997	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962011998	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962011999	1 probable transmembrane helix predicted for BF638R2843 by TMHMM2.0 at aa 7-29
862962012000	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012001	2 probable transmembrane helices predicted for BF638R2844 by TMHMM2.0 at aa 13-32 and 47-69
862962012002	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
862962012003	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
862962012004	acyl-activating enzyme (AAE) consensus motif; other site
862962012005	AMP binding site [chemical binding]; other site
862962012006	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
862962012007	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2e-06
862962012008	HMMPfam hit to PF00501, AMP-binding enzyme, score 1e-106
862962012009	PS00455 Putative AMP-binding domain signature.
862962012010	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962012011	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962012012	N-terminal plug; other site
862962012013	ligand-binding site [chemical binding]; other site
862962012014	HMMPfam hit to PF00593, TonB dependent receptor, score 3e-09
862962012015	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.2e-07
862962012016	Signal peptide predicted for BF638R2846 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.955 between residues 28 and 29
862962012017	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962012018	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962012019	dimer interface [polypeptide binding]; other site
862962012020	phosphorylation site [posttranslational modification]
862962012021	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962012022	ATP binding site [chemical binding]; other site
862962012023	Mg2+ binding site [ion binding]; other site
862962012024	G-X-G motif; other site
862962012025	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.3e-23
862962012026	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.1e-05
862962012027	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962012028	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962012029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962012030	ATP binding site [chemical binding]; other site
862962012031	G-X-G motif; other site
862962012032	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.6e-22
862962012033	1 probable transmembrane helix predicted for BF638R2848 by TMHMM2.0 at aa 608-630
862962012034	HMMPfam hit to PF07495, Two component regulator three Y motif, score 3.4e-08
862962012035	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012036	HMMPfam hit to PF07494, Two component regulator propeller, score 20
862962012037	HMMPfam hit to PF07494, Two component regulator propeller, score 26
862962012038	HMMPfam hit to PF07494, Two component regulator propeller, score 0.1
862962012039	Signal peptide predicted for BF638R2848 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.912 between residues 18 and 19
862962012040	PS00443 Glutamine amidotransferases class-II active site.
862962012041	FOG: WD40 repeat [General function prediction only]; Region: COG2319
862962012042	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
862962012043	PS00678 Trp-Asp (WD) repeats signature.
862962012044	HMMPfam hit to PF00400, WD domain, G-beta repeat, score 3.2e-06
862962012045	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012046	Signal peptide predicted for BF638R2849 by SignalP 2.0 HMM (Signal peptide probability 0.643) with cleavage site probability 0.617 between residues 33 and 34
862962012047	1 probable transmembrane helix predicted for BF638R2849 by TMHMM2.0 at aa 7-29
862962012048	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
862962012049	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
862962012050	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
862962012051	anti sigma factor interaction site; other site
862962012052	regulatory phosphorylation site [posttranslational modification]; other site
862962012053	HMMPfam hit to PF01740, STAS domain, score 5e-15
862962012054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962012055	active site
862962012056	phosphorylation site [posttranslational modification]
862962012057	intermolecular recognition site; other site
862962012058	dimerization interface [polypeptide binding]; other site
862962012059	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
862962012060	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
862962012061	HMMPfam hit to PF07228, Stage II sporulation protein E (SpoIIE), score 1.1e-61
862962012062	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.1e-24
862962012063	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
862962012064	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
862962012065	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
862962012066	NAD(P) binding site [chemical binding]; other site
862962012067	homodimer interface [polypeptide binding]; other site
862962012068	substrate binding site [chemical binding]; other site
862962012069	active site
862962012070	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 3e-159
862962012071	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012072	4 probable transmembrane helices predicted for BF638R2856 by TMHMM2.0 at aa 15-37, 56-73, 83-105 and 110-132
862962012073	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
862962012074	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
862962012075	putative active site [active]
862962012076	PhoH-like protein; Region: PhoH; pfam02562
862962012077	HMMPfam hit to PF02562, PhoH-like protein, score 1.7e-33
862962012078	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012079	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
862962012080	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
862962012081	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 9.1e-09
862962012082	PS01011 Folylpolyglutamate synthase signature 1.
862962012083	PS01012 Folylpolyglutamate synthase signature 2.
862962012084	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
862962012085	homotrimer interaction site [polypeptide binding]; other site
862962012086	putative active site [active]
862962012087	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 2.7e-63
862962012088	PS01094 Uncharacterized protein family UPF0076 signature.
862962012089	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
862962012090	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962012091	TPR motif; other site
862962012092	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962012093	binding surface
862962012094	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.1; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.081
862962012095	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0082; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.073
862962012096	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.063; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.024
862962012097	Signal peptide predicted for BF638R2860 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.778 between residues 20 and 21
862962012098	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
862962012099	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
862962012100	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
862962012101	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 2.5e-44
862962012102	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962012103	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
862962012104	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
862962012105	Walker A/P-loop; other site
862962012106	ATP binding site [chemical binding]; other site
862962012107	Q-loop/lid; other site
862962012108	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
862962012109	ABC transporter signature motif; other site
862962012110	Walker B; other site
862962012111	D-loop; other site
862962012112	H-loop/switch region; other site
862962012113	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012114	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
862962012115	Flavoprotein; Region: Flavoprotein; pfam02441
862962012116	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
862962012117	HMMPfam hit to PF04127, DNA / pantothenate metabolism flavoprote, score 3.9e-29
862962012118	HMMPfam hit to PF02441, Flavoprotein, score 7.3e-45
862962012119	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
862962012120	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
862962012121	active site
862962012122	catalytic site [active]
862962012123	substrate binding site [chemical binding]; other site
862962012124	HMMPfam hit to PF00929, Exonuclease, score 2.6e-21
862962012125	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962012126	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
862962012127	DNA polymerase III subunit beta; Validated; Region: PRK05643
862962012128	putative DNA binding surface [nucleotide binding]; other site
862962012129	dimer interface [polypeptide binding]; other site
862962012130	beta-clamp/translesion DNA polymerase binding surface; other site
862962012131	beta-clamp/clamp loader binding surface; other site
862962012132	HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-te, score 1.7e-15
862962012133	HMMPfam hit to PF02767, DNA polymerase III beta subunit, cent, score 1.3e-15
862962012134	HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-te, score 2.5e-18
862962012135	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
862962012136	Signal peptide predicted for BF638R2867 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.643 between residues 32 and 33
862962012137	1 probable transmembrane helix predicted for BF638R2867 by TMHMM2.0 at aa 5-27
862962012138	putative hydrolase; Provisional; Region: PRK02113
862962012139	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
862962012140	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 5.5e-13
862962012141	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
862962012142	FAD binding domain; Region: FAD_binding_4; pfam01565
862962012143	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
862962012144	HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine reductas, score 1.7e-31
862962012145	Domain of unknown function (DUF4348); Region: DUF4348; pfam14254
862962012146	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012147	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962012148	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962012149	NAD(P) binding site [chemical binding]; other site
862962012150	active site
862962012151	2-amino-3-ketobutyrate coenzyme A ligase; Provisional; Region: PRK06939
862962012152	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
862962012153	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962012154	catalytic residue [active]
862962012155	HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.8e-47
862962012156	PS00215 Mitochondrial energy transfer proteins signature.
862962012157	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
862962012158	Signal peptide predicted for BF638R2874 by SignalP 2.0 HMM (Signal peptide probability 0.868) with cleavage site probability 0.755 between residues 22 and 23
862962012159	3 probable transmembrane helices predicted for BF638R2874 by TMHMM2.0 at aa 10-29, 68-90 and 94-111
862962012160	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012161	Signal peptide predicted for BF638R2875 by SignalP 2.0 HMM (Signal peptide probability 0.627) with cleavage site probability 0.290 between residues 24 and 25
862962012162	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cd13119
862962012163	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cd13119
862962012164	Signal peptide predicted for BF638R2876 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.616 between residues 24 and 25
862962012165	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962012166	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012167	Signal peptide predicted for BF638R2877 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.715 between residues 21 and 22
862962012168	Signal peptide predicted for BF638R2878 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.799 between residues 28 and 29
862962012169	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012170	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
862962012171	Signal peptide predicted for BF638R2879 by SignalP 2.0 HMM (Signal peptide probability 0.934) with cleavage site probability 0.894 between residues 37 and 38
862962012172	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962012173	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012174	Signal peptide predicted for BF638R2881 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.750 between residues 24 and 25
862962012175	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012176	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
862962012177	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962012178	ligand binding site [chemical binding]; other site
862962012179	1 probable transmembrane helix predicted for BF638R2882 by TMHMM2.0 at aa 20-39
862962012180	Signal peptide predicted for BF638R2882 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 38 and 39
862962012181	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962012182	Signal peptide predicted for BF638R2884 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.972 between residues 18 and 19
862962012183	Transcriptional regulator; Region: Rrf2; cl17282
862962012184	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
862962012185	active site
862962012186	catalytic residues [active]
862962012187	DNA binding site [nucleotide binding]
862962012188	Int/Topo IB signature motif; other site
862962012189	HMMPfam hit to PF00589, Phage integrase family, score 1.2e-05
862962012190	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
862962012191	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
862962012192	PS00962 Ribosomal protein S2 signature 1.
862962012193	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
862962012194	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
862962012195	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
862962012196	Ferritin-like domain; Region: Ferritin; pfam00210
862962012197	ferroxidase diiron center [ion binding]; other site
862962012198	HMMPfam hit to PF00210, Ferritin-like domain, score 9.9e-52
862962012199	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
862962012200	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
862962012201	active site
862962012202	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
862962012203	substrate binding site [chemical binding]; other site
862962012204	catalytic residues [active]
862962012205	dimer interface [polypeptide binding]; other site
862962012206	HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 2e-35
862962012207	HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 5e-56
862962012208	PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
862962012209	aspartate kinase III; Validated; Region: PRK09084
862962012210	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
862962012211	putative catalytic residues [active]
862962012212	nucleotide binding site [chemical binding]; other site
862962012213	aspartate binding site [chemical binding]; other site
862962012214	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
862962012215	dimer interface [polypeptide binding]; other site
862962012216	allosteric regulatory binding pocket; other site
862962012217	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
862962012218	dimer interface [polypeptide binding]; other site
862962012219	HMMPfam hit to PF00696, Amino acid kinase family, score 2.9e-30
862962012220	PS00324 Aspartokinase signature.
862962012221	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
862962012222	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962012223	Walker A/P-loop; other site
862962012224	ATP binding site [chemical binding]; other site
862962012225	Q-loop/lid; other site
862962012226	ABC transporter signature motif; other site
862962012227	Walker B; other site
862962012228	D-loop; other site
862962012229	H-loop/switch region; other site
862962012230	HMMPfam hit to PF00005, ABC transporter, score 6.8e-51
862962012231	PS00211 ABC transporters family signature.
862962012232	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012233	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
862962012234	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
862962012235	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
862962012236	metal binding site [ion binding]; metal-binding site
862962012237	HMMPfam hit to PF01503, Phosphoribosyl-ATP pyrophosphohydrolase, score 6.5e-32
862962012238	HMMPfam hit to PF01502, Phosphoribosyl-AMP cyclohydrolase, score 6.3e-43
862962012239	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
862962012240	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
862962012241	substrate binding site [chemical binding]; other site
862962012242	glutamase interaction surface [polypeptide binding]; other site
862962012243	HMMPfam hit to PF00977, Histidine biosynthesis protein, score 2.1e-126
862962012244	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
862962012245	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
862962012246	catalytic residues [active]
862962012247	HMMPfam hit to PF00977, Histidine biosynthesis protein, score 1.1e-86
862962012248	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
862962012249	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
862962012250	putative active site [active]
862962012251	oxyanion strand; other site
862962012252	catalytic triad [active]
862962012253	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.5e-38
862962012254	HMMPfam hit to PF01174, SNO glutamine amidotransferase family, score 0.002
862962012255	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 0.00039
862962012256	PS00442 Glutamine amidotransferases class-I active site.
862962012257	Uncharacterized conserved protein [Function unknown]; Region: COG1479
862962012258	Protein of unknown function DUF262; Region: DUF262; pfam03235
862962012259	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
862962012260	Uncharacterized conserved protein [Function unknown]; Region: COG3586
862962012261	HMMPfam hit to PF07510, Protein of unknown function (DUF1524), score 2.2e-32
862962012262	HMMPfam hit to PF03235, Protein of unknown function DUF262, score 3.3e-07
862962012263	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
862962012264	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962012265	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.3
862962012266	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.15
862962012267	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
862962012268	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
862962012269	Right handed beta helix region; Region: Beta_helix; pfam13229
862962012270	PS00241 Growth factor and cytokines receptors family signature 1.
862962012271	Signal peptide predicted for BF638R2909 by SignalP 2.0 HMM (Signal peptide probability 0.750) with cleavage site probability 0.727 between residues 24 and 25
862962012272	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
862962012273	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962012274	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962012275	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 1.2e-87
862962012276	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 3.7e-81
862962012277	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012278	Signal peptide predicted for BF638R2910 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 20 and 21
862962012279	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
862962012280	HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D), score 7.4e-11
862962012281	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012282	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
862962012283	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
862962012284	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
862962012285	B12 binding site [chemical binding]; other site
862962012286	cobalt ligand [ion binding]; other site
862962012287	HMMPfam hit to PF02310, B12 binding domain, score 3.1e-34
862962012288	HMMPfam hit to PF02607, B12 binding domain, score 8.3e-20
862962012289	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
862962012290	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
862962012291	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962012292	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962012293	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962012294	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 1.1e-78
862962012295	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 6.2e-70
862962012296	Signal peptide predicted for BF638R2915 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.947 between residues 19 and 20
862962012297	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962012298	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962012299	SusD family; Region: SusD; pfam07980
862962012300	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012301	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962012302	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962012303	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962012304	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962012305	HMMPfam hit to PF00593, TonB dependent receptor, score 3.8e-19
862962012306	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.9e-21
862962012307	PS00217 Sugar transport proteins signature 2.
862962012308	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 2.2e-07
862962012309	Signal peptide predicted for BF638R2917 by SignalP 2.0 HMM (Signal peptide probability 0.809) with cleavage site probability 0.771 between residues 43 and 44
862962012310	1 probable transmembrane helix predicted for BF638R2917 by TMHMM2.0 at aa 21-43
862962012311	FecR protein; Region: FecR; pfam04773
862962012312	HMMPfam hit to PF04773, FecR protein, score 6.4e-21
862962012313	1 probable transmembrane helix predicted for BF638R2918 by TMHMM2.0 at aa 89-111; 1 probable transmembrane helix predicted for BF638R2919 by TMHMM2.0 at aa 91-113
862962012314	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962012315	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962012316	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962012317	HMMPfam hit to PF04542, Sigma-70 region, score 9.6e-05
862962012318	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_3; cd03140
862962012319	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
862962012320	conserved cys residue [active]
862962012321	HMMPfam hit to PF01965, DJ-1/PfpI family, score 1.1e-16
862962012322	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
862962012323	active site
862962012324	8-oxo-dGMP binding site [chemical binding]; other site
862962012325	nudix motif; other site
862962012326	metal binding site [ion binding]; metal-binding site
862962012327	HMMPfam hit to PF00293, NUDIX domain, score 2.2e-18
862962012328	PS00893 mutT domain signature.
862962012329	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
862962012330	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
862962012331	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962012332	S-adenosylmethionine binding site [chemical binding]; other site
862962012333	HMMPfam hit to PF05971, Protein of unknown function (DUF890), score 5.9e-145
862962012334	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
862962012335	active site
862962012336	Low molecular weight phosphatase family; Region: LMWPc; cl00105
862962012337	Protein of unknown function (DUF3584); Region: DUF3584; pfam12128
862962012338	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012339	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
862962012340	EamA-like transporter family; Region: EamA; pfam00892
862962012341	10 probable transmembrane helices predicted for BF638R2930 by TMHMM2.0 at aa 20-39, 49-65, 78-100, 105-127, 132-149, 159-181, 193-212, 227-249, 256-273 and 283-305
862962012342	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 8.7e-16
862962012343	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2e-13
862962012344	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012345	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
862962012346	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
862962012347	HMMPfam hit to PF02386, Cation transport protein, score 1.1e-62
862962012348	10 probable transmembrane helices predicted for BF638R2932 by TMHMM2.0 at aa 28-50, 56-75, 87-109, 153-175, 196-218, 254-276, 289-311, 346-368, 407-429 and 472-494
862962012349	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012350	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012351	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962012352	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962012353	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 8.6e-11
862962012354	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.2
862962012355	putative transporter; Provisional; Region: PRK11043
862962012356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962012357	putative substrate translocation pore; other site
862962012358	Signal peptide predicted for BF638R2935 by SignalP 2.0 HMM (Signal peptide probability 0.636) with cleavage site probability 0.263 between residues 38 and 39
862962012359	12 probable transmembrane helices predicted for BF638R2935 by TMHMM2.0 at aa 11-33, 48-70, 77-99, 103-125, 138-160, 166-185, 218-240, 250-272, 277-299, 303-325, 338-360 and 364-383
862962012360	HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00012
862962012361	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.1e-36
862962012362	PS00216 Sugar transport proteins signature 1.
862962012363	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012364	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012365	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
862962012366	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962012367	NAD(P) binding site [chemical binding]; other site
862962012368	active site
862962012369	HMMPfam hit to PF00106, short chain dehydrogenase, score 6.8e-17
862962012370	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962012371	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962012372	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
862962012373	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 9.2e-05
862962012374	PS00041 Bacterial regulatory proteins, araC family signature.
862962012375	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 6.7e-11
862962012376	HMMPfam hit to PF06445, Bacterial transcription activator, effect, score 2.2e-34
862962012377	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
862962012378	Predicted acetyltransferase [General function prediction only]; Region: COG2388
862962012379	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962012380	TIGR01777 family protein; Region: yfcH
862962012381	NAD(P) binding site [chemical binding]; other site
862962012382	active site
862962012383	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
862962012384	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
862962012385	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
862962012386	active site
862962012387	HMMPfam hit to PF01183, Glycosyl hydrolases family, score 3.7e-77
862962012388	1 probable transmembrane helix predicted for BF638R2941 by TMHMM2.0 at aa 36-58
862962012389	Signal peptide predicted for BF638R2941 by SignalP 2.0 HMM (Signal peptide probability 0.871) with cleavage site probability 0.539 between residues 51 and 52
862962012390	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
862962012391	Asp-box motif; other site
862962012392	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.42
862962012393	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.3
862962012394	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2.5
862962012395	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.2
862962012396	Signal peptide predicted for BF638R2942 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.832 between residues 22 and 23
862962012397	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
862962012398	pyrophosphate-dependent phosphofructokinase; Region: PLN02251
862962012399	active site
862962012400	ADP/pyrophosphate binding site [chemical binding]; other site
862962012401	dimerization interface [polypeptide binding]; other site
862962012402	allosteric effector site; other site
862962012403	fructose-1,6-bisphosphate binding site; other site
862962012404	HMMPfam hit to PF00365, Phosphofructokinase, score 4.4e-10
862962012405	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962012406	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962012407	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962012408	Peptidase M60-like family; Region: M60-like; pfam13402
862962012409	HMMPfam hit to PF00754, F5/8 type C domain, score 3.6e-14
862962012410	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012411	Signal peptide predicted for BF638R2945 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.747 between residues 20 and 21
862962012412	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962012413	HMMPfam hit to PF00754, F5/8 type C domain, score 6.4e-05
862962012414	Signal peptide predicted for BF638R2946 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.649 between residues 24 and 25
862962012415	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962012416	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962012417	SusD family; Region: SusD; pfam07980
862962012418	Signal peptide predicted for BF638R2947 by SignalP 2.0 HMM (Signal peptide probability 0.681) with cleavage site probability 0.489 between residues 23 and 24
862962012419	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962012420	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962012421	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962012422	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962012423	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962012424	HMMPfam hit to PF00593, TonB dependent receptor, score 7.7e-20
862962012425	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012426	PS00237 G-protein coupled receptors signature.
862962012427	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.9e-17
862962012428	1 probable transmembrane helix predicted for BF638R2948 by TMHMM2.0 at aa 13-35
862962012429	Signal peptide predicted for BF638R2948 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.947 between residues 29 and 30
862962012430	FecR protein; Region: FecR; pfam04773
862962012431	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962012432	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962012433	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962012434	DNA binding residues [nucleotide binding]
862962012435	HMMPfam hit to PF04542, Sigma-70 region, score 3.1e-10
862962012436	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
862962012437	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.2e-36
862962012438	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.3e-30
862962012439	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012440	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012441	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962012442	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962012443	12 probable transmembrane helices predicted for BF638R2953 by TMHMM2.0 at aa 21-43, 349-371, 378-400, 404-426, 449-471, 486-508, 549-568, 874-893, 900-922, 932-954, 974-996 and 1011-1033
862962012444	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962012445	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962012446	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962012447	HMMPfam hit to PF00529, HlyD family secretion protein, score 5e-25
862962012448	1 probable transmembrane helix predicted for BF638R2954 by TMHMM2.0 at aa 17-34
862962012449	Signal peptide predicted for BF638R2954 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.701 between residues 28 and 29
862962012450	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
862962012451	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
862962012452	active site
862962012453	nucleophile elbow; other site
862962012454	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962012455	Signal peptide predicted for BF638R2955 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 23 and 24
862962012456	1 probable transmembrane helix predicted for BF638R2955 by TMHMM2.0 at aa 5-24
862962012457	HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.5e-40
862962012458	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
862962012459	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
862962012460	putative acyl-acceptor binding pocket; other site
862962012461	HMMPfam hit to PF01553, Acyltransferase, score 2.7e-10
862962012462	1 probable transmembrane helix predicted for BF638R2957 by TMHMM2.0 at aa 63-80
862962012463	C-N hydrolase family amidase; Provisional; Region: PRK10438
862962012464	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
862962012465	putative active site [active]
862962012466	catalytic triad [active]
862962012467	dimer interface [polypeptide binding]; other site
862962012468	multimer interface [polypeptide binding]; other site
862962012469	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 3.3e-18
862962012470	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
862962012471	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
862962012472	active site
862962012473	dimer interface [polypeptide binding]; other site
862962012474	HMMPfam hit to PF01979, Amidohydrolase family, score 1.1e-07
862962012475	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
862962012476	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
862962012477	active site
862962012478	trimer interface [polypeptide binding]; other site
862962012479	allosteric site; other site
862962012480	active site lid [active]
862962012481	hexamer (dimer of trimers) interface [polypeptide binding]; other site
862962012482	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
862962012483	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 4.9e-44
862962012484	HMMPfam hit to PF02585, GlcNAc-PI de-N-acetylase, score 4.6e-37
862962012485	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
862962012486	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
862962012487	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
862962012488	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
862962012489	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cl02713
862962012490	active site
862962012491	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962012492	Interdomain contacts; other site
862962012493	Cytokine receptor motif; other site
862962012494	Signal peptide predicted for BF638R2962 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21
862962012495	HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 4.9e-06
862962012496	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.0057
862962012497	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012498	Signal peptide predicted for BF638R2964 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.992 between residues 28 and 29
862962012499	1 probable transmembrane helix predicted for BF638R2964 by TMHMM2.0 at aa 13-30
862962012500	SirA-like protein; Region: SirA; pfam01206
862962012501	CPxP  motif; other site
862962012502	Protein of unknown function (DUF456); Region: DUF456; pfam04306
862962012503	4 probable transmembrane helices predicted for BF638R2968 by TMHMM2.0 at aa 5-27, 51-73, 86-108 and 132-154
862962012504	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012505	HMMPfam hit to PF04306, Protein of unknown function (DUF456), score 8e-08
862962012506	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
862962012507	hypothetical protein; Provisional; Region: PRK00955
862962012508	PS00092 N-6 Adenine-specific DNA methylases signature.
862962012509	HMMPfam hit to PF04055, Radical SAM superfamily, score 0.0088
862962012510	PS01278 Uncharacterized protein family UPF0004 signature.
862962012511	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
862962012512	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
862962012513	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962012514	ATP binding site [chemical binding]; other site
862962012515	putative Mg++ binding site [ion binding]; other site
862962012516	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962012517	nucleotide binding region [chemical binding]; other site
862962012518	ATP-binding site [chemical binding]; other site
862962012519	TRCF domain; Region: TRCF; pfam03461
862962012520	HMMPfam hit to PF03461, TRCF domain, score 1.6e-07
862962012521	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 3.3e-18
862962012522	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.3e-33
862962012523	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012524	HMMPfam hit to PF02559, CarD-like/TRCF domain, score 6e-38
862962012525	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
862962012526	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
862962012527	Ligand binding site; other site
862962012528	Putative Catalytic site; other site
862962012529	DXD motif; other site
862962012530	HMMPfam hit to PF00535, Glycosyl transferase, score 3.6e-28
862962012531	dihydroorotase; Reviewed; Region: PRK09236
862962012532	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
862962012533	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
862962012534	active site
862962012535	HMMPfam hit to PF01979, Amidohydrolase family, score 1.6e-09
862962012536	PS00483 Dihydroorotase signature 2.
862962012537	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
862962012538	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
862962012539	HMMPfam hit to PF02965, Vitamin B12 dependent methionine synthas, score 2e-43
862962012540	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962012541	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962012542	Signal peptide predicted for BF638R2976 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 21 and 22
862962012543	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
862962012544	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962012545	Signal peptide predicted for BF638R2977 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.747 between residues 19 and 20
862962012546	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962012547	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962012548	Signal peptide predicted for BF638R2979 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.929 between residues 19 and 20
862962012549	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
862962012550	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962012551	Interdomain contacts; other site
862962012552	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012553	Signal peptide predicted for BF638R2980 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.690 between residues 19 and 20
862962012554	3 probable transmembrane helices predicted for BF638R2982 by TMHMM2.0 at aa 42-64, 79-96 and 116-135
862962012555	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
862962012556	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
862962012557	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962012558	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962012559	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962012560	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-17
862962012561	4 probable transmembrane helices predicted for BF638R2985 by TMHMM2.0 at aa 49-71, 76-98, 119-138 and 148-170
862962012562	phosphodiesterase YaeI; Provisional; Region: PRK11340
862962012563	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
862962012564	putative active site [active]
862962012565	putative metal binding site [ion binding]; other site
862962012566	5 probable transmembrane helices predicted for BF638R2986 by TMHMM2.0 at aa 5-24, 34-56, 69-91, 106-128 and 359-378
862962012567	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 6.7e-16
862962012568	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962012569	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962012570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962012571	Walker A/P-loop; other site
862962012572	ATP binding site [chemical binding]; other site
862962012573	Q-loop/lid; other site
862962012574	ABC transporter signature motif; other site
862962012575	Walker B; other site
862962012576	D-loop; other site
862962012577	H-loop/switch region; other site
862962012578	Signal peptide predicted for BF638R2987 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.438 between residues 27 and 28
862962012579	6 probable transmembrane helices predicted for BF638R2987 by TMHMM2.0 at aa 13-35, 50-72, 133-151, 155-174, 235-257 and 272-294
862962012580	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2e-37
862962012581	HMMPfam hit to PF00005, ABC transporter, score 1.6e-51
862962012582	PS00211 ABC transporters family signature.
862962012583	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
862962012584	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962012585	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
862962012586	Walker A/P-loop; other site
862962012587	ATP binding site [chemical binding]; other site
862962012588	Q-loop/lid; other site
862962012589	ABC transporter signature motif; other site
862962012590	Walker B; other site
862962012591	D-loop; other site
862962012592	H-loop/switch region; other site
862962012593	5 probable transmembrane helices predicted for BF638R2988 by TMHMM2.0 at aa 32-54, 74-96, 153-170, 174-193 and 267-286
862962012594	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 6.1e-56
862962012595	HMMPfam hit to PF00005, ABC transporter, score 3.3e-57
862962012596	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012597	PS00211 ABC transporters family signature.
862962012598	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
862962012599	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962012600	Walker A/P-loop; other site
862962012601	ATP binding site [chemical binding]; other site
862962012602	Q-loop/lid; other site
862962012603	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962012604	ABC transporter signature motif; other site
862962012605	Walker B; other site
862962012606	D-loop; other site
862962012607	H-loop/switch region; other site
862962012608	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012609	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012610	exonuclease subunit SbcD; Provisional; Region: PRK10966
862962012611	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
862962012612	active site
862962012613	metal binding site [ion binding]; metal-binding site
862962012614	DNA binding site [nucleotide binding]
862962012615	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
862962012616	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.2e-11
862962012617	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
862962012618	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
862962012619	putative acyl-acceptor binding pocket; other site
862962012620	2 probable transmembrane helices predicted for BF638R2991 by TMHMM2.0 at aa 56-78 and 98-115
862962012621	HMMPfam hit to PF01553, Acyltransferase, score 3.1e-31
862962012622	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962012623	Protein export membrane protein; Region: SecD_SecF; cl14618
862962012624	Protein export membrane protein; Region: SecD_SecF; cl14618
862962012625	12 probable transmembrane helices predicted for BF638R2992 by TMHMM2.0 at aa 13-35, 345-362, 369-391, 395-417, 429-451, 461-483, 527-549, 906-925, 932-951, 961-980, 1001-1023 and 1038-1060
862962012626	12 probable transmembrane helices predicted for BF638R2993 by TMHMM2.0 at aa 21-43, 352-369, 376-398, 402-424, 436-458, 468-490, 534-556, 913-932, 939-958, 968-987, 1008-1030 and 1045-1067
862962012627	Signal peptide predicted for BF638R2993 by SignalP 2.0 HMM (Signal peptide probability 0.749) with cleavage site probability 0.685 between residues 38 and 39
862962012628	Signal peptide predicted for BF638R2992 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.872 between residues 31 and 32
862962012629	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962012630	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.5e-06
862962012631	Signal peptide predicted for BF638R2994 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.802 between residues 21 and 22
862962012632	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962012633	Protein export membrane protein; Region: SecD_SecF; cl14618
862962012634	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 1.9e-107
862962012635	11 probable transmembrane helices predicted for BF638R2995 by TMHMM2.0 at aa 10-32, 341-360, 364-383, 388-410, 443-465, 472-494, 535-554, 863-885, 900-922, 963-982 and 997-1019
862962012636	Signal peptide predicted for BF638R2995 by SignalP 2.0 HMM (Signal peptide probability 0.787) with cleavage site probability 0.336 between residues 34 and 35
862962012637	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012638	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962012639	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962012640	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962012641	Signal peptide predicted for BF638R2996 by SignalP 2.0 HMM (Signal peptide probability 0.897) with cleavage site probability 0.540 between residues 21 and 22
862962012642	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012643	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
862962012644	O-Antigen ligase; Region: Wzy_C; pfam04932
862962012645	9 probable transmembrane helices predicted for BF638R2997 by TMHMM2.0 at aa 12-29, 44-66, 79-101, 116-138, 151-173, 177-196, 209-231, 298-320 and 350-372
862962012646	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012647	HMMPfam hit to PF04932, O-Antigen Polymerase, score 2.7e-08
862962012648	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
862962012649	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
862962012650	Catalytic site [active]
862962012651	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
862962012652	PS00761 Signal peptidases I signature 3.
862962012653	HMMPfam hit to PF00717, Peptidase S24-like, score 6.9e-06
862962012654	PS00501 Signal peptidases I serine active site.
862962012655	1 probable transmembrane helix predicted for BF638R2998 by TMHMM2.0 at aa 13-35
862962012656	Signal peptide predicted for BF638R2999 by SignalP 2.0 HMM (Signal peptide probability 0.917) with cleavage site probability 0.344 between residues 26 and 27
862962012657	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012658	Signal peptide predicted for BF638R3000 by SignalP 2.0 HMM (Signal peptide probability 0.834) with cleavage site probability 0.754 between residues 19 and 20
862962012659	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012660	Transglutaminase/protease-like homologues; Region: TGc; smart00460
862962012661	PS00037 Myb DNA-binding domain repeat signature 1.
862962012662	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012663	1 probable transmembrane helix predicted for BF638R3003 by TMHMM2.0 at aa 7-26
862962012664	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
862962012665	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962012666	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962012667	HMMPfam hit to PF07610, Protein of unknown function (DUF1573), score 3.6e-11
862962012668	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012669	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012670	1 probable transmembrane helix predicted for BF638R3006 by TMHMM2.0 at aa 7-24
862962012671	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012672	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012673	NVEALA protein; Region: NVEALA; pfam14055
862962012674	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012675	Signal peptide predicted for BF638R3008 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.220 between residues 30 and 31
862962012676	1 probable transmembrane helix predicted for BF638R3008 by TMHMM2.0 at aa 5-24
862962012677	Signal peptide predicted for BF638R3009 by SignalP 2.0 HMM (Signal peptide probability 0.774) with cleavage site probability 0.621 between residues 19 and 20
862962012678	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012679	NVEALA protein; Region: NVEALA; pfam14055
862962012680	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
862962012681	DNA binding site [nucleotide binding]
862962012682	Signal peptide predicted for BF638R3011 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.644 between residues 21 and 22
862962012683	2 probable transmembrane helices predicted for BF638R3011 by TMHMM2.0 at aa 5-27 and 198-220
862962012684	Domain of unknown function (DUF3244); Region: DUF3244; pfam11589
862962012685	1 probable transmembrane helix predicted for BF638R3012 by TMHMM2.0 at aa 3-25; 1 probable transmembrane helix predicted for BF638R3013 by TMHMM2.0 at aa 5-27
862962012686	Signal peptide predicted for BF638R3013 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.809 between residues 23 and 24
862962012687	Signal peptide predicted for BF638R3012 by SignalP 2.0 HMM (Signal peptide probability 0.924) with cleavage site probability 0.725 between residues 21 and 22
862962012688	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962012689	binding surface
862962012690	TPR motif; other site
862962012691	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962012692	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962012693	binding surface
862962012694	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962012695	TPR motif; other site
862962012696	2 probable transmembrane helices predicted for BF638R3014 by TMHMM2.0 at aa 13-32 and 375-394
862962012697	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.44
862962012698	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.5
862962012699	Signal peptide predicted for BF638R3014 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.498 between residues 43 and 44
862962012700	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012701	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962012702	PS00962 Ribosomal protein S2 signature 1.
862962012703	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012704	anaerobic sulfatase-maturase; Provisional; Region: PRK13745
862962012705	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962012706	FeS/SAM binding site; other site
862962012707	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
862962012708	HMMPfam hit to PF04055, Radical SAM superfamily, score 6.7e-19
862962012709	Peptidase S46; Region: Peptidase_S46; pfam10459
862962012710	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
862962012711	Signal peptide predicted for BF638R3017 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.905 between residues 21 and 22
862962012712	Peptidase S46; Region: Peptidase_S46; pfam10459
862962012713	Peptidase S7, Flavivirus NS3 serine protease; Region: Peptidase_S7; pfam00949
862962012714	Signal peptide predicted for BF638R3018 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.890 between residues 20 and 21
862962012715	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
862962012716	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
862962012717	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962012718	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962012719	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
862962012720	putative active site [active]
862962012721	putative metal binding site [ion binding]; other site
862962012722	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.3e-14
862962012723	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962012724	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962012725	catalytic residues [active]
862962012726	HMMPfam hit to PF00085, Thioredoxin, score 1.7e-22
862962012727	PS00194 Thioredoxin family active site.
862962012728	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
862962012729	catalytic residues [active]
862962012730	HMMPfam hit to PF00085, Thioredoxin, score 7.2e-17
862962012731	PS00194 Thioredoxin family active site.
862962012732	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
862962012733	putative FMN binding site [chemical binding]; other site
862962012734	NADPH bind site [chemical binding]; other site
862962012735	HMMPfam hit to PF00881, Nitroreductase family, score 0.00034
862962012736	Signal peptide predicted for BF638R3024 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 19 and 20
862962012737	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
862962012738	Rubredoxin; Region: Rubredoxin; pfam00301
862962012739	iron binding site [ion binding]; other site
862962012740	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
862962012741	Rubrerythrin [Energy production and conversion]; Region: COG1592
862962012742	diiron binding motif [ion binding]; other site
862962012743	HMMPfam hit to PF02915, Rubrerythrin, score 4.6e-14
862962012744	HMMPfam hit to PF00301, Rubredoxin, score 3.4e-09
862962012745	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
862962012746	metal binding site 2 [ion binding]; metal-binding site
862962012747	putative DNA binding helix; other site
862962012748	metal binding site 1 [ion binding]; metal-binding site
862962012749	dimer interface [polypeptide binding]; other site
862962012750	structural Zn2+ binding site [ion binding]; other site
862962012751	HMMPfam hit to PF01475, Ferric uptake regulator family, score 3.9e-16
862962012752	Protein of unknown function (DUF805); Region: DUF805; pfam05656
862962012753	HMMPfam hit to PF05656, Protein of unknown function (DUF805), score 2.3e-40
862962012754	3 probable transmembrane helices predicted for BF638R3027 by TMHMM2.0 at aa 21-39, 43-65 and 77-99
862962012755	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
862962012756	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
862962012757	active site
862962012758	Zn binding site [ion binding]; other site
862962012759	HMMPfam hit to PF01432, Peptidase family M3, score 1.4e-137
862962012760	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962012761	Signal peptide predicted for BF638R3028 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.292 between residues 33 and 34
862962012762	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012763	NAD synthetase; Reviewed; Region: nadE; PRK02628
862962012764	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
862962012765	multimer interface [polypeptide binding]; other site
862962012766	active site
862962012767	catalytic triad [active]
862962012768	protein interface 1 [polypeptide binding]; other site
862962012769	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
862962012770	homodimer interface [polypeptide binding]; other site
862962012771	NAD binding pocket [chemical binding]; other site
862962012772	ATP binding pocket [chemical binding]; other site
862962012773	Mg binding site [ion binding]; other site
862962012774	active-site loop [active]
862962012775	HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1.5e-07
862962012776	HMMPfam hit to PF02540, NAD synthase, score 7.8e-53
862962012777	Signal peptide predicted for BF638R3030 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.560 between residues 19 and 20
862962012778	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962012779	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962012780	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962012781	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962012782	Signal peptide predicted for BF638R3031 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 21 and 22
862962012783	1 probable transmembrane helix predicted for BF638R3031 by TMHMM2.0 at aa 5-24
862962012784	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.2e-16
862962012785	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
862962012786	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962012787	Signal peptide predicted for BF638R3032 by SignalP 2.0 HMM (Signal peptide probability 0.695) with cleavage site probability 0.250 between residues 22 and 23
862962012788	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012789	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962012790	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962012791	putative active site [active]
862962012792	putative metal binding site [ion binding]; other site
862962012793	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962012794	Signal peptide predicted for BF638R3033 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.804 between residues 19 and 20
862962012795	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 8.8e-16
862962012796	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
862962012797	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962012798	active site
862962012799	motif I; other site
862962012800	motif II; other site
862962012801	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
862962012802	putative active site pocket [active]
862962012803	4-fold oligomerization interface [polypeptide binding]; other site
862962012804	metal binding residues [ion binding]; metal-binding site
862962012805	3-fold/trimer interface [polypeptide binding]; other site
862962012806	HMMPfam hit to PF00475, Imidazoleglycerol-phosphate dehydratase, score 5.7e-85
862962012807	PS00955 Imidazoleglycerol-phosphate dehydratase signature 2.
862962012808	PS00954 Imidazoleglycerol-phosphate dehydratase signature 1.
862962012809	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
862962012810	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962012811	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962012812	homodimer interface [polypeptide binding]; other site
862962012813	catalytic residue [active]
862962012814	HMMPfam hit to PF00155, Aminotransferase class I and II, score 5.9e-33
862962012815	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962012816	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
862962012817	histidinol dehydrogenase; Region: hisD; TIGR00069
862962012818	NAD binding site [chemical binding]; other site
862962012819	dimerization interface [polypeptide binding]; other site
862962012820	product binding site; other site
862962012821	substrate binding site [chemical binding]; other site
862962012822	zinc binding site [ion binding]; other site
862962012823	catalytic residues [active]
862962012824	HMMPfam hit to PF00815, Histidinol dehydrogenase, score 2.8e-232
862962012825	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
862962012826	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
862962012827	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
862962012828	HMMPfam hit to PF01634, ATP phosphoribosyltransferase, score 6.6e-53
862962012829	PS01316 ATP phosphoribosyltransferase signature.
862962012830	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
862962012831	CoenzymeA binding site [chemical binding]; other site
862962012832	subunit interaction site [polypeptide binding]; other site
862962012833	PHB binding site; other site
862962012834	HMMPfam hit to PF03061, Thioesterase superfamily, score 1.2e-09
862962012835	Pirin; Region: Pirin; pfam02678
862962012836	Pirin-related protein [General function prediction only]; Region: COG1741
862962012837	HMMPfam hit to PF02678, Pirin, score 7.7e-45
862962012838	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012839	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
862962012840	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
862962012841	8 probable transmembrane helices predicted for BF638R3040 by TMHMM2.0 at aa 218-240, 261-283, 296-318, 338-360, 375-397, 410-432, 447-469 and 482-504
862962012842	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembran, score 6.1e-06
862962012843	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012844	Signal peptide predicted for BF638R3040 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 19 and 20
862962012845	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
862962012846	HMMPfam hit to PF07876, Stress responsive A/B Barrel Domain, score 6.9e-26
862962012847	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
862962012848	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
862962012849	ATP-binding site [chemical binding]; other site
862962012850	Sugar specificity; other site
862962012851	Pyrimidine base specificity; other site
862962012852	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 3.2e-51
862962012853	PS00227 Tubulin subunits alpha, beta, and gamma signature.
862962012854	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012855	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
862962012856	substrate binding pocket [chemical binding]; other site
862962012857	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
862962012858	membrane-bound complex binding site; other site
862962012859	hinge residues; other site
862962012860	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
862962012861	N-acetyl-D-glucosamine binding site [chemical binding]; other site
862962012862	catalytic residue [active]
862962012863	Signal peptide predicted for BF638R3043 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.791 between residues 25 and 26
862962012864	HMMPfam hit to PF01464, Transglycosylase SLT domain, score 7.8e-27
862962012865	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
862962012866	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
862962012867	Na binding site [ion binding]; other site
862962012868	13 probable transmembrane helices predicted for BF638R3044 by TMHMM2.0 at aa 4-26, 47-69, 73-95, 124-142, 152-174, 186-205, 248-270, 283-305, 340-357, 385-407, 417-436, 443-462 and 489-511
862962012869	HMMPfam hit to PF00474, Sodium:solute symporter family, score 3.5e-39
862962012870	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012871	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
862962012872	putative FMN binding site [chemical binding]; other site
862962012873	HMMPfam hit to PF00881, Nitroreductase family, score 1.5e-34
862962012874	Signal peptide predicted for BF638R3045 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.803 between residues 29 and 30
862962012875	1 probable transmembrane helix predicted for BF638R3045 by TMHMM2.0 at aa 7-29
862962012876	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012877	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
862962012878	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
862962012879	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
862962012880	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
862962012881	substrate binding pocket [chemical binding]; other site
862962012882	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
862962012883	B12 binding site [chemical binding]; other site
862962012884	cobalt ligand [ion binding]; other site
862962012885	HMMPfam hit to PF02310, B12 binding domain, score 2.4e-27
862962012886	HMMPfam hit to PF02607, B12 binding domain, score 1.1e-35
862962012887	HMMPfam hit to PF00809, Pterin binding enzyme, score 5e-73
862962012888	HMMPfam hit to PF02574, Homocysteine S-methyltransferase, score 6.8e-130
862962012889	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
862962012890	SmpB-tmRNA interface; other site
862962012891	HMMPfam hit to PF01668, SmpB protein, score 9.9e-26
862962012892	PS01317 Protein smpB signature.
862962012893	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
862962012894	5 probable transmembrane helices predicted for BF638R3048 by TMHMM2.0 at aa 34-56, 66-88, 109-128, 132-154 and 161-183
862962012895	NigD-like protein; Region: NigD; pfam12667
862962012896	Signal peptide predicted for BF638R3049 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.451 between residues 34 and 35
862962012897	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012898	Domain of unknown function (DUF4375); Region: DUF4375; pfam14300
862962012899	TIGR03987 family protein; Region: TIGR03987
862962012900	4 probable transmembrane helices predicted for BF638R3051 by TMHMM2.0 at aa 10-31, 38-60, 75-97 and 110-132
862962012901	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
862962012902	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
862962012903	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012904	GGGtGRT protein; Region: GGGtGRT; pfam14057
862962012905	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962012906	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962012907	Int/Topo IB signature motif; other site
862962012908	HMMPfam hit to PF00589, Phage integrase family, score 1.4e-08
862962012909	PS00194 Thioredoxin family active site.
862962012910	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012911	Nuclease-related domain; Region: NERD; pfam08378
862962012912	Family description; Region: UvrD_C_2; pfam13538
862962012913	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012914	Domain of unknown function, B. Theta Gene description (DUF3871); Region: DUF3871; pfam12987
862962012915	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
862962012916	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
862962012917	MPN+ (JAMM) motif; other site
862962012918	Zinc-binding site [ion binding]; other site
862962012919	HMMPfam hit to PF04002, RadC, DNA repair protein, score 2.4e-32
862962012920	PS01302 DNA repair protein radC family signature.
862962012921	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
862962012922	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
862962012923	catalytic residues [active]
862962012924	catalytic nucleophile [active]
862962012925	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 1.5e-14
862962012926	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
862962012927	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
862962012928	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
862962012929	Signal peptide predicted for BF638R3066 by SignalP 2.0 HMM (Signal peptide probability 0.662) with cleavage site probability 0.512 between residues 22 and 23
862962012930	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012931	Signal peptide predicted for BF638R3067 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.564 between residues 21 and 22
862962012932	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012933	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
862962012934	Signal peptide predicted for BF638R3068 by SignalP 2.0 HMM (Signal peptide probability 0.879) with cleavage site probability 0.390 between residues 23 and 24
862962012935	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012936	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.3e-23
862962012937	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
862962012938	Signal peptide predicted for BF638R3069 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.694 between residues 24 and 25
862962012939	GGGtGRT protein; Region: GGGtGRT; pfam14057
862962012940	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12879
862962012941	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
862962012942	dimer interface [polypeptide binding]; other site
862962012943	active site
862962012944	CoA binding pocket [chemical binding]; other site
862962012945	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
862962012946	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
862962012947	active site
862962012948	Na/Ca binding site [ion binding]; other site
862962012949	catalytic site [active]
862962012950	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 2.6e-71
862962012951	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
862962012952	HMMPfam hit to PF03631, Ribonuclease BN-like family, score 1.1e-49
862962012953	6 probable transmembrane helices predicted for BF638R3075 by TMHMM2.0 at aa 39-61, 106-128, 148-170, 190-212, 224-246 and 251-273
862962012954	Domain of unknown function (DUF202); Region: DUF202; pfam02656
862962012955	2 probable transmembrane helices predicted for BF638R3076 by TMHMM2.0 at aa 61-83 and 88-106
862962012957	This hit extended beyond the end of the feature by 1 aa and was clipped.; PS00294 Prenyl group binding site (CAAX box).
862962012958	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00025
862962012959	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962012960	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 6.3e-07
862962012961	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962012962	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
862962012963	transcription termination factor Rho; Provisional; Region: PRK12608
862962012964	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
862962012965	RNA binding site [nucleotide binding]; other site
862962012966	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
862962012967	multimer interface [polypeptide binding]; other site
862962012968	Walker A motif; other site
862962012969	ATP binding site [chemical binding]; other site
862962012970	Walker B motif; other site
862962012971	HMMPfam hit to PF07498, Rho termination factor, N-terminal domai, score 3.1e-13
862962012972	HMMPfam hit to PF07497, Rho termination factor, RNA-binding doma, score 1.6e-46
862962012973	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleoti, score 7.1e-69
862962012974	PS00017 ATP/GTP-binding site motif A (P-loop).
862962012975	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
862962012976	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962012977	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962012978	dimer interface [polypeptide binding]; other site
862962012979	phosphorylation site [posttranslational modification]
862962012980	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962012981	ATP binding site [chemical binding]; other site
862962012982	Mg2+ binding site [ion binding]; other site
862962012983	G-X-G motif; other site
862962012984	Signal peptide predicted for BF638R3079 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 23 and 24
862962012985	2 probable transmembrane helices predicted for BF638R3079 by TMHMM2.0 at aa 5-24 and 340-362
862962012986	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.066
862962012987	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962012988	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.8e-18
862962012989	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.3e-33
862962012990	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962012991	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962012992	dimer interface [polypeptide binding]; other site
862962012993	phosphorylation site [posttranslational modification]
862962012994	Signal peptide predicted for BF638R3080 by SignalP 2.0 HMM (Signal peptide probability 0.957) with cleavage site probability 0.616 between residues 20 and 21
862962012995	1 probable transmembrane helix predicted for BF638R3080 by TMHMM2.0 at aa 391-413
862962012996	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1e-18
862962012997	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
862962012998	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962012999	12 probable transmembrane helices predicted for BF638R3081 by TMHMM2.0 at aa 7-24, 39-61, 80-102, 126-148, 155-177, 190-212, 233-255, 275-295, 316-338, 353-375, 382-404 and 408-430
862962013000	HMMPfam hit to PF01554, MatE, score 1.1e-23
862962013001	signal recognition particle protein; Provisional; Region: PRK10867
862962013002	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
862962013003	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
862962013004	P loop; other site
862962013005	GTP binding site [chemical binding]; other site
862962013006	Signal peptide binding domain; Region: SRP_SPB; pfam02978
862962013007	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 1.2e-25
862962013008	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 9.1e-117
862962013009	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013010	PS00300 SRP54-type proteins GTP-binding domain signature.
862962013011	HMMPfam hit to PF02978, Signal peptide binding domain, score 1.4e-50
862962013012	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962013013	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962013014	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962013015	catalytic residues [active]
862962013016	PS00194 Thioredoxin family active site.
862962013017	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
862962013018	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
862962013019	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
862962013020	homodimer interface [polypeptide binding]; other site
862962013021	NADP binding site [chemical binding]; other site
862962013022	substrate binding site [chemical binding]; other site
862962013023	HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohyd, score 4.5e-57
862962013024	PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
862962013025	HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohyd, score 6.8e-102
862962013026	PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
862962013027	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962013028	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962013029	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962013030	catalytic residues [active]
862962013031	Signal peptide predicted for BF638R3085 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.646 between residues 23 and 24
862962013032	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013033	HMMPfam hit to PF00255, Glutathione peroxidase, score 2.9e-05
862962013034	PS00194 Thioredoxin family active site.
862962013035	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
862962013036	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
862962013037	putative active site [active]
862962013038	putative metal binding site [ion binding]; other site
862962013039	Signal peptide predicted for BF638R3086 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.928 between residues 20 and 21
862962013040	1 probable transmembrane helix predicted for BF638R3087 by TMHMM2.0 at aa 7-29
862962013041	6 probable transmembrane helices predicted for BF638R3088 by TMHMM2.0 at aa 13-35, 57-79, 103-125, 135-157, 170-189 and 193-215
862962013042	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
862962013043	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962013044	Walker A/P-loop; other site
862962013045	ATP binding site [chemical binding]; other site
862962013046	Q-loop/lid; other site
862962013047	ABC transporter signature motif; other site
862962013048	Walker B; other site
862962013049	D-loop; other site
862962013050	H-loop/switch region; other site
862962013051	HMMPfam hit to PF00005, ABC transporter, score 7.5e-28
862962013052	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
862962013054	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
862962013055	3 probable transmembrane helices predicted for BF638R3090 by TMHMM2.0 at aa 21-39, 140-162 and 169-188
862962013056	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.44
862962013057	Signal peptide predicted for BF638R3090 by SignalP 2.0 HMM (Signal peptide probability 0.914) with cleavage site probability 0.773 between residues 40 and 41
862962013058	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.031
862962013059	Signal peptide predicted for BF638R3091 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.708 between residues 26 and 27
862962013060	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013061	Signal peptide predicted for BF638R3092 by SignalP 2.0 HMM (Signal peptide probability 0.817) with cleavage site probability 0.664 between residues 32 and 33
862962013062	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013063	Signal peptide predicted for BF638R3093 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.698 between residues 24 and 25
862962013064	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013065	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962013066	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962013067	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962013068	HMMPfam hit to PF00593, TonB dependent receptor, score 1.6e-09
862962013069	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.7e-10
862962013070	1 probable transmembrane helix predicted for BF638R3094 by TMHMM2.0 at aa 5-27
862962013071	Signal peptide predicted for BF638R3094 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.633 between residues 23 and 24
862962013072	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
862962013073	1 probable transmembrane helix predicted for BF638R3096 by TMHMM2.0 at aa 9-31
862962013074	Signal peptide predicted for BF638R3096 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.957 between residues 26 and 27
862962013075	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14971
862962013076	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962013077	Walker A motif; other site
862962013078	ATP binding site [chemical binding]; other site
862962013079	Walker B motif; other site
862962013080	arginine finger; other site
862962013081	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
862962013082	HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 0.0018
862962013083	HMMPfam hit to PF00004, ATPase family associated with various, score 8.8e-06
862962013084	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013085	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
862962013086	Septum formation initiator; Region: DivIC; pfam04977
862962013087	1 probable transmembrane helix predicted for BF638R3098 by TMHMM2.0 at aa 10-29
862962013088	Signal peptide predicted for BF638R3099 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.791 between residues 44 and 45
862962013089	3 probable transmembrane helices predicted for BF638R3099 by TMHMM2.0 at aa 7-29, 33-50 and 62-81
862962013090	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
862962013091	1 probable transmembrane helix predicted for BF638R3100 by TMHMM2.0 at aa 15-37
862962013092	Signal peptide predicted for BF638R3100 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.607 between residues 30 and 31
862962013093	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962013094	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.4e-05
862962013095	1 probable transmembrane helix predicted for BF638R3101 by TMHMM2.0 at aa 48-70
862962013096	LytTr DNA-binding domain; Region: LytTR; smart00850
862962013097	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 7.5e-15
862962013098	4 probable transmembrane helices predicted for BF638R3102 by TMHMM2.0 at aa 27-49, 54-76, 97-119 and 124-146
862962013099	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
862962013100	Signal peptide predicted for BF638R3103 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.389 between residues 26 and 27
862962013101	1 probable transmembrane helix predicted for BF638R3103 by TMHMM2.0 at aa 7-24
862962013102	1 probable transmembrane helix predicted for BF638R3104 by TMHMM2.0 at aa 4-26
862962013103	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
862962013104	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
862962013105	metal binding site [ion binding]; metal-binding site
862962013106	dimer interface [polypeptide binding]; other site
862962013107	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 4.8e-13
862962013108	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962013109	putative catalytic site [active]
862962013110	putative metal binding site [ion binding]; other site
862962013111	putative phosphate binding site [ion binding]; other site
862962013112	Signal peptide predicted for BF638R3106 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.753 between residues 19 and 20
862962013113	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 9.4e-12
862962013114	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
862962013115	Mechanosensitive ion channel; Region: MS_channel; pfam00924
862962013116	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 6.1e-23
862962013117	5 probable transmembrane helices predicted for BF638R3107 by TMHMM2.0 at aa 30-52, 73-95, 110-132, 144-166 and 176-198
862962013118	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
862962013119	active site
862962013120	intersubunit interactions; other site
862962013121	catalytic residue [active]
862962013122	HMMPfam hit to PF00923, Transaldolase, score 2.9e-64
862962013123	PS01054 Transaldolase signature 1.
862962013124	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962013125	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
862962013126	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962013127	sugar binding site [chemical binding]; other site
862962013128	HMMPfam hit to PF00754, F5/8 type C domain, score 3.9e-14
862962013129	Signal peptide predicted for BF638R3109 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.941 between residues 20 and 21
862962013130	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
862962013131	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962013132	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962013133	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962013134	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
862962013135	HMMPfam hit to PF02930, Beta galactosidase small chain, C ter, score 2.1e-31
862962013136	HMMPfam hit to PF02929, Beta galactosidase small chain, N ter, score 5.4e-14
862962013137	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962013138	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 5.8e-111
862962013139	PS00719 Glycosyl hydrolases family 2 signature 1.
862962013140	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 2e-15
862962013141	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.5e-96
862962013142	Signal peptide predicted for BF638R3110 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.961 between residues 23 and 24
862962013143	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962013144	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962013145	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962013146	active site
862962013147	Fn3 associated; Region: Fn3_assoc; pfam13287
862962013148	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
862962013149	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013150	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 1e-157
862962013151	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.0038
862962013152	Signal peptide predicted for BF638R3111 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.708 between residues 20 and 21
862962013153	Sulfatase; Region: Sulfatase; cl17466
862962013154	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962013155	HMMPfam hit to PF00884, Sulfatase, score 5.1e-47
862962013156	PS00149 Sulfatases signature 2.
862962013157	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013158	Signal peptide predicted for BF638R3112 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.418 between residues 20 and 21
862962013159	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962013160	Sulfatase; Region: Sulfatase; pfam00884
862962013161	Signal peptide predicted for BF638R3113 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.953 between residues 23 and 24
862962013162	HMMPfam hit to PF00884, Sulfatase, score 2.9e-50
862962013163	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
862962013164	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962013165	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962013166	active site
862962013167	PS00214 Cytosolic fatty-acid binding proteins signature.
862962013168	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyti, score 1.2e-148
862962013169	Signal peptide predicted for BF638R3114 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.422 between residues 27 and 28
862962013170	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013171	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962013172	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962013173	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962013174	2 probable transmembrane helices predicted for BF638R3115 by TMHMM2.0 at aa 9-31 and 759-781
862962013175	HMMPfam hit to PF07494, Two component regulator propeller, score 7.1
862962013176	HMMPfam hit to PF07494, Two component regulator propeller, score 0.99
862962013177	HMMPfam hit to PF07494, Two component regulator propeller, score 29
862962013178	HMMPfam hit to PF07494, Two component regulator propeller, score 0.19
862962013179	HMMPfam hit to PF07494, Two component regulator propeller, score 0.85
862962013180	HMMPfam hit to PF07494, Two component regulator propeller, score 0.14
862962013181	HMMPfam hit to PF07494, Two component regulator propeller, score 16
862962013182	HMMPfam hit to PF07495, Two component regulator three Y motif, score 4.1e-10
862962013183	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.051
862962013184	PS00041 Bacterial regulatory proteins, araC family signature.
862962013185	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.4e-12
862962013186	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
862962013187	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
862962013188	putative active site; other site
862962013189	catalytic residue [active]
862962013190	HMMPfam hit to PF01791, Deoxyribose-phosphate aldolase, score 8e-107
862962013191	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
862962013192	catalytic core [active]
862962013193	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
862962013194	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 8.2e-110
862962013195	PS00175 Phosphoglycerate mutase family phosphohistidine signature.
862962013196	Right handed beta helix region; Region: Beta_helix; pfam13229
862962013197	Right handed beta helix region; Region: Beta_helix; pfam13229
862962013198	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
862962013199	protein binding site [polypeptide binding]; other site
862962013200	Signal peptide predicted for BF638R3118 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.911 between residues 18 and 19
862962013201	PS00761 Signal peptidases I signature 3.
862962013202	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 0.036
862962013203	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962013204	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
862962013205	Walker A/P-loop; other site
862962013206	ATP binding site [chemical binding]; other site
862962013207	Q-loop/lid; other site
862962013208	ABC transporter signature motif; other site
862962013209	Walker B; other site
862962013210	D-loop; other site
862962013211	H-loop/switch region; other site
862962013212	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962013213	Walker A/P-loop; other site
862962013214	ATP binding site [chemical binding]; other site
862962013215	Q-loop/lid; other site
862962013216	ABC transporter signature motif; other site
862962013217	Walker B; other site
862962013218	D-loop; other site
862962013219	H-loop/switch region; other site
862962013220	HMMPfam hit to PF00005, ABC transporter, score 1.2e-37
862962013221	PS00211 ABC transporters family signature.
862962013222	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013223	HMMPfam hit to PF00005, ABC transporter, score 2.8e-20
862962013224	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013225	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962013226	Sulfatase; Region: Sulfatase; pfam00884
862962013227	HMMPfam hit to PF00884, Sulfatase, score 1e-52
862962013228	PS00523 Sulfatases signature 1.
862962013229	Signal peptide predicted for BF638R3120 by SignalP 2.0 HMM (Signal peptide probability 0.651) with cleavage site probability 0.523 between residues 21 and 22
862962013230	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962013231	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962013232	active site
862962013233	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyti, score 1.3e-109
862962013234	Signal peptide predicted for BF638R3121 by SignalP 2.0 HMM (Signal peptide probability 0.781) with cleavage site probability 0.483 between residues 15 and 16
862962013235	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962013236	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962013237	SusD family; Region: SusD; pfam07980
862962013238	Signal peptide predicted for BF638R3122 by SignalP 2.0 HMM (Signal peptide probability 0.950) with cleavage site probability 0.776 between residues 21 and 22
862962013239	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013240	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962013241	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962013242	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962013243	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962013244	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962013245	HMMPfam hit to PF00593, TonB dependent receptor, score 3.6e-15
862962013246	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-18
862962013247	Signal peptide predicted for BF638R3123 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.986 between residues 33 and 34
862962013248	FecR protein; Region: FecR; pfam04773
862962013249	This hit extended beyond the end of the feature by 1 aa and was clipped.; PS00294 Prenyl group binding site (CAAX box).
862962013250	HMMPfam hit to PF04773, FecR protein, score 1.6e-26
862962013251	1 probable transmembrane helix predicted for BF638R3124 by TMHMM2.0 at aa 79-101
862962013252	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962013253	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962013254	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962013255	HMMPfam hit to PF04542, Sigma-70 region, score 1.5e-13
862962013256	pullulanase, type I; Region: pulA_typeI; TIGR02104
862962013257	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
862962013258	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
862962013259	Ca binding site [ion binding]; other site
862962013260	active site
862962013261	catalytic site [active]
862962013262	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
862962013263	PS00079 Multicopper oxidases signature 1.
862962013264	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 2.4e-11
862962013265	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 9.3e-13
862962013266	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013267	Signal peptide predicted for BF638R3126 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.797 between residues 19 and 20
862962013268	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
862962013269	active site
862962013270	putative DNA-binding cleft [nucleotide binding]; other site
862962013271	dimer interface [polypeptide binding]; other site
862962013272	HMMPfam hit to PF02075, Crossover junction endodeoxyribonuclease Ruv, score 3e-44
862962013273	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
862962013274	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
862962013275	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
862962013276	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
862962013277	dimer interface [polypeptide binding]; other site
862962013278	motif 1; other site
862962013279	active site
862962013280	motif 2; other site
862962013281	motif 3; other site
862962013282	HMMPfam hit to PF01409, tRNA synthetases class II core domain (F, score 2.9e-124
862962013283	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962013284	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962013285	putative substrate translocation pore; other site
862962013286	12 probable transmembrane helices predicted for BF638R3131 by TMHMM2.0 at aa 25-47, 62-84, 91-113, 117-139, 151-173, 177-199, 225-247, 251-273, 286-308, 323-345, 357-379 and 384-401
862962013287	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-49
862962013288	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013289	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013290	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013291	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
862962013292	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
862962013293	minor groove reading motif; other site
862962013294	helix-hairpin-helix signature motif; other site
862962013295	substrate binding pocket [chemical binding]; other site
862962013296	active site
862962013297	HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 2.1e-18
862962013298	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 9.2e-06
862962013299	Phosphoglycerate kinase; Region: PGK; pfam00162
862962013300	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
862962013301	substrate binding site [chemical binding]; other site
862962013302	hinge regions; other site
862962013303	ADP binding site [chemical binding]; other site
862962013304	catalytic site [active]
862962013305	HMMPfam hit to PF00162, Phosphoglycerate kinase, score 5.8e-201
862962013306	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
862962013307	NMT1/THI5 like; Region: NMT1; pfam09084
862962013308	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
862962013309	Signal peptide predicted for BF638R3135 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.794 between residues 21 and 22
862962013310	HMMPfam hit to PF07396, Phosphate-selective porin O and P, score 2.2e-05
862962013311	Predicted membrane protein [Function unknown]; Region: COG2311
862962013312	Protein of unknown function (DUF418); Region: DUF418; cl12135
862962013313	Protein of unknown function (DUF418); Region: DUF418; pfam04235
862962013314	HMMPfam hit to PF04171, Protein of unknown function (DUF405), score 3.7e-14
862962013315	8 probable transmembrane helices predicted for BF638R3136 by TMHMM2.0 at aa 21-40, 60-82, 103-125, 216-238, 245-267, 282-304, 323-340 and 350-372
862962013316	HMMPfam hit to PF04235, Protein of unknown function (DUF418), score 4.3e-18
862962013317	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
862962013318	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962013319	binding surface
862962013320	TPR motif; other site
862962013321	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962013322	binding surface
862962013323	TPR motif; other site
862962013324	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.07; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.9
862962013325	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00054; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0004
862962013326	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0013; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00023
862962013327	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.046; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.27
862962013328	Family of unknown function (DUF3836); Region: DUF3836; pfam12930
862962013329	Signal peptide predicted for BF638R3138 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.736 between residues 25 and 26
862962013330	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
862962013331	active site
862962013332	catalytic residues [active]
862962013333	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 9.2e-09
862962013334	Signal peptide predicted for BF638R3140 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.781 between residues 20 and 21
862962013335	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962013336	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
862962013337	acyl-activating enzyme (AAE) consensus motif; other site
862962013338	AMP binding site [chemical binding]; other site
862962013339	active site
862962013340	CoA binding site [chemical binding]; other site
862962013341	HMMPfam hit to PF00501, AMP-binding enzyme, score 7.1e-100
862962013342	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013343	PS00455 Putative AMP-binding domain signature.
862962013344	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
862962013345	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
862962013346	Signal peptide predicted for BF638R3142 by SignalP 2.0 HMM (Signal peptide probability 0.854) with cleavage site probability 0.664 between residues 21 and 22
862962013347	7 probable transmembrane helices predicted for BF638R3142 by TMHMM2.0 at aa 3-22, 37-59, 79-101, 303-325, 348-367, 400-417 and 430-447
862962013348	HMMPfam hit to PF03062, MBOAT family, score 1.3e-44
862962013349	1 probable transmembrane helix predicted for BF638R3143 by TMHMM2.0 at aa 13-35
862962013350	Signal peptide predicted for BF638R3144 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.530 between residues 25 and 26
862962013351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013352	Maf-like protein; Region: Maf; pfam02545
862962013353	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
862962013354	active site
862962013355	dimer interface [polypeptide binding]; other site
862962013356	HMMPfam hit to PF02545, Maf-like protein, score 3.8e-46
862962013357	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
862962013358	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962013359	active site
862962013360	motif I; other site
862962013361	motif II; other site
862962013362	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
862962013363	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
862962013364	NAD(P)H:flavin oxidoreductase-like family 2.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_2; cd02151
862962013365	putative FMN binding site [chemical binding]; other site
862962013366	HMMPfam hit to PF00881, Nitroreductase family, score 1.1e-20
862962013367	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
862962013368	active site clefts [active]
862962013369	zinc binding site [ion binding]; other site
862962013370	dimer interface [polypeptide binding]; other site
862962013371	HMMPfam hit to PF00484, Carbonic anhydrase, score 5.4e-65
862962013372	PS00190 Cytochrome c family heme-binding site signature.
862962013373	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
862962013374	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
862962013375	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
862962013376	dimer interface [polypeptide binding]; other site
862962013377	substrate binding site [chemical binding]; other site
862962013378	metal binding site [ion binding]; metal-binding site
862962013379	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4.6e-15
862962013380	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
862962013381	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
862962013382	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
862962013383	HMMPfam hit to PF01039, Carboxyl transferase domain, score 4.6e-289
862962013384	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013385	Lamin Tail Domain; Region: LTD; pfam00932
862962013386	sodium pump decarboxylases, gamma subunit; Region: oadG_fam; TIGR01195
862962013387	Signal peptide predicted for BF638R3153 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.883 between residues 24 and 25
862962013388	1 probable transmembrane helix predicted for BF638R3153 by TMHMM2.0 at aa 194-216
862962013389	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
862962013390	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962013391	carboxyltransferase (CT) interaction site; other site
862962013392	biotinylation site [posttranslational modification]; other site
862962013393	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.4e-23
862962013394	PS00188 Biotin-requiring enzymes attachment site.
862962013395	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
862962013396	9 probable transmembrane helices predicted for BF638R3155 by TMHMM2.0 at aa 20-42, 49-68, 83-105, 118-140, 167-189, 221-243, 258-280, 292-314 and 363-385
862962013397	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacet, score 2.4e-201
862962013398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962013399	binding surface
862962013400	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962013401	TPR motif; other site
862962013402	Signal peptide predicted for BF638R3156 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.978 between residues 23 and 24
862962013403	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.7; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.97
862962013404	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00029; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3.8e-05
862962013405	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3
862962013406	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.6; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.019
862962013407	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.1
862962013408	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.078
862962013409	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962013410	binding surface
862962013411	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962013412	TPR motif; other site
862962013413	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962013414	binding surface
862962013415	TPR motif; other site
862962013416	Signal peptide predicted for BF638R3157 by SignalP 2.0 HMM (Signal peptide probability 0.948) with cleavage site probability 0.533 between residues 18 and 19
862962013417	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.51; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.57
862962013418	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00023; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0096
862962013419	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 3.2; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.5
862962013420	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.4
862962013421	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
862962013422	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_3; cd11340
862962013423	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
862962013424	Ca binding site [ion binding]; other site
862962013425	active site
862962013426	homodimer interface [polypeptide binding]; other site
862962013427	catalytic site [active]
862962013428	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
862962013429	Signal peptide predicted for BF638R3158 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.978 between residues 19 and 20
862962013430	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.7e-65
862962013431	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013432	Transcriptional regulators [Transcription]; Region: MarR; COG1846
862962013433	MarR family; Region: MarR; pfam01047
862962013434	HMMPfam hit to PF01047, MarR family, score 5.1e-14
862962013435	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
862962013436	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962013437	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962013438	Signal peptide predicted for BF638R3160 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.573 between residues 36 and 37
862962013439	1 probable transmembrane helix predicted for BF638R3160 by TMHMM2.0 at aa 19-41
862962013440	HMMPfam hit to PF00529, HlyD family secretion protein, score 1.1e-25
862962013441	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962013442	putative substrate translocation pore; other site
862962013443	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
862962013444	13 probable transmembrane helices predicted for BF638R3161 by TMHMM2.0 at aa 12-34, 54-71, 107-129, 144-166, 173-195, 210-227, 239-257, 277-299, 312-334, 339-361, 374-393, 408-430 and 494-516
862962013445	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.1e-06
862962013446	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962013447	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
862962013448	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
862962013449	intersubunit interface [polypeptide binding]; other site
862962013450	active site
862962013451	zinc binding site [ion binding]; other site
862962013452	Na+ binding site [ion binding]; other site
862962013453	HMMPfam hit to PF01116, Fructose-bisphosphate aldolase class-II, score 4.2e-114
862962013454	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962013455	putative catalytic site [active]
862962013456	putative metal binding site [ion binding]; other site
862962013457	putative phosphate binding site [ion binding]; other site
862962013458	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 0.00016
862962013459	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
862962013460	HMMPfam hit to PF01197, Ribosomal protein L31, score 1.5e-15
862962013461	PS01143 Ribosomal protein L31 signature.
862962013462	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962013463	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962013464	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962013465	catalytic residues [active]
862962013466	PS00194 Thioredoxin family active site.
862962013467	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
862962013468	Signal peptide predicted for BF638R3166 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.997 between residues 19 and 20
862962013469	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013470	HMMPfam hit to PF01435, Peptidase family M48, score 3.7e-05
862962013471	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962013472	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962013473	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
862962013474	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_4; cd11350
862962013475	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
862962013476	active site
862962013477	catalytic site [active]
862962013478	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 3e-12
862962013479	Signal peptide predicted for BF638R3167 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.635 between residues 22 and 23
862962013480	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013481	SusE outer membrane protein; Region: SusE; pfam14292
862962013482	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
862962013483	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
862962013484	starch binding site [chemical binding]; other site
862962013485	Uncharacterized subgroup of the CBM-SusE-F_like superfamily; Region: CBM_SusE-F_like_u1; cd12967
862962013486	starch binding site [chemical binding]; other site
862962013487	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
862962013488	starch binding site [chemical binding]; other site
862962013489	Signal peptide predicted for BF638R3168 by SignalP 2.0 HMM (Signal peptide probability 0.918) with cleavage site probability 0.498 between residues 20 and 21
862962013490	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013491	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962013492	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962013493	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013494	Signal peptide predicted for BF638R3169 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.449 between residues 23 and 24
862962013495	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962013496	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962013497	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962013498	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962013499	HMMPfam hit to PF00593, TonB dependent receptor, score 1.8e-22
862962013500	PS00018 EF-hand calcium-binding domain.
862962013501	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.4e-19
862962013502	Signal peptide predicted for BF638R3170 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 35 and 36
862962013503	Transcriptional regulators [Transcription]; Region: PurR; COG1609
862962013504	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
862962013505	DNA binding site [nucleotide binding]
862962013506	domain linker motif; other site
862962013507	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
862962013508	dimerization interface [polypeptide binding]; other site
862962013509	ligand binding site [chemical binding]; other site
862962013510	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 7.5e-10
862962013511	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 7.5e-18
862962013512	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962013513	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962013514	putative substrate translocation pore; other site
862962013515	12 probable transmembrane helices predicted for BF638R3172 by TMHMM2.0 at aa 7-29, 49-68, 80-102, 107-129, 153-175, 188-205, 254-276, 291-313, 320-339, 344-366, 379-401 and 411-429
862962013516	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.1e-21
862962013517	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013518	maltose phosphorylase; Provisional; Region: PRK13807
862962013519	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
862962013520	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
862962013521	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
862962013522	HMMPfam hit to PF03636, Glycosyl hydrolase family 65, N-termi, score 1.7e-62
862962013523	HMMPfam hit to PF03632, Glycosyl hydrolase family, score 8.3e-157
862962013524	HMMPfam hit to PF03633, Glycosyl hydrolase family 65, C-termi, score 3.3e-12
862962013525	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962013526	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962013527	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962013528	Signal peptide predicted for BF638R3174 by SignalP 2.0 HMM (Signal peptide probability 0.946) with cleavage site probability 0.410 between residues 20 and 21
862962013529	Signal peptide predicted for BF638R3175 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.403 between residues 17 and 18
862962013530	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013531	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962013532	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 2.2e-39
862962013533	12 probable transmembrane helices predicted for BF638R3176 by TMHMM2.0 at aa 22-39, 340-362, 369-391, 396-415, 439-461, 476-498, 531-553, 868-885, 892-911, 915-937, 958-980 and 990-1012
862962013534	PS00904 Protein prenyltransferases alpha subunit repeat signature.
862962013535	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013536	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962013537	Signal peptide predicted for BF638R3177 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21
862962013538	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.8e-18
862962013539	PS00018 EF-hand calcium-binding domain.
862962013540	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.5e-19
862962013541	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013542	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
862962013543	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
862962013544	dimerization interface [polypeptide binding]; other site
862962013545	ATP binding site [chemical binding]; other site
862962013546	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
862962013547	dimerization interface [polypeptide binding]; other site
862962013548	ATP binding site [chemical binding]; other site
862962013549	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
862962013550	putative active site [active]
862962013551	catalytic triad [active]
862962013552	HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 4.6e-07
862962013553	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 5.2e-22
862962013554	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 6e-16
862962013555	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962013556	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962013557	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962013558	dimer interface [polypeptide binding]; other site
862962013559	phosphorylation site [posttranslational modification]
862962013560	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962013561	ATP binding site [chemical binding]; other site
862962013562	Mg2+ binding site [ion binding]; other site
862962013563	G-X-G motif; other site
862962013564	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962013565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962013566	active site
862962013567	phosphorylation site [posttranslational modification]
862962013568	intermolecular recognition site; other site
862962013569	dimerization interface [polypeptide binding]; other site
862962013570	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962013571	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962013572	Signal peptide predicted for BF638R3180 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.875 between residues 17 and 18
862962013573	HMMPfam hit to PF07494, Two component regulator propeller, score 1.2
862962013574	HMMPfam hit to PF07494, Two component regulator propeller, score 20
862962013575	HMMPfam hit to PF07494, Two component regulator propeller, score 16
862962013576	HMMPfam hit to PF07494, Two component regulator propeller, score 36
862962013577	HMMPfam hit to PF07494, Two component regulator propeller, score 2.8
862962013578	HMMPfam hit to PF07494, Two component regulator propeller, score 2.6
862962013579	HMMPfam hit to PF07494, Two component regulator propeller, score 11
862962013580	HMMPfam hit to PF07494, Two component regulator propeller, score 0.29
862962013581	HMMPfam hit to PF07494, Two component regulator propeller, score 4
862962013582	HMMPfam hit to PF07495, Two component regulator three Y motif, score 7.1e-13
862962013583	1 probable transmembrane helix predicted for BF638R3180 by TMHMM2.0 at aa 768-790
862962013584	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 9.7e-06
862962013585	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 6.5e-28
862962013586	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.4e-30
862962013587	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.0042
862962013588	PS00041 Bacterial regulatory proteins, araC family signature.
862962013589	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2e-08
862962013590	Chromate transporter; Region: Chromate_transp; pfam02417
862962013591	HMMPfam hit to PF02417, Chromate transporter, score 9.3e-37
862962013592	5 probable transmembrane helices predicted for BF638R3181 by TMHMM2.0 at aa 7-29, 49-71, 78-100, 115-134 and 141-163
862962013593	Chromate transporter; Region: Chromate_transp; pfam02417
862962013594	HMMPfam hit to PF02417, Chromate transporter, score 2.9e-37
862962013595	4 probable transmembrane helices predicted for BF638R3182 by TMHMM2.0 at aa 7-29, 78-100, 112-133 and 143-160
862962013596	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013597	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
862962013598	HMMPfam hit to PF02638, Uncharacterized BCR, COG1649, score 7.9e-83
862962013599	Signal peptide predicted for BF638R3183 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.976 between residues 20 and 21
862962013600	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
862962013601	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
862962013602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962013603	ATP binding site [chemical binding]; other site
862962013604	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
862962013605	ABC transporter signature motif; other site
862962013606	Walker B; other site
862962013607	D-loop; other site
862962013608	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
862962013609	HMMPfam hit to PF00005, ABC transporter, score 6.2e-08
862962013610	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013611	PS00211 ABC transporters family signature.
862962013612	HMMPfam hit to PF00005, ABC transporter, score 9.2e-21
862962013613	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013614	PS00190 Cytochrome c family heme-binding site signature.
862962013615	Signal peptide predicted for BF638R3185 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.967 between residues 19 and 20
862962013616	2 probable transmembrane helices predicted for BF638R3186 by TMHMM2.0 at aa 9-28 and 38-55
862962013617	Signal peptide predicted for BF638R3186 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.681 between residues 22 and 23
862962013618	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
862962013619	Carbon starvation protein CstA; Region: CstA; pfam02554
862962013620	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
862962013621	12 probable transmembrane helices predicted for BF638R3187 by TMHMM2.0 at aa 2-19, 52-71, 128-150, 160-178, 185-207, 227-246, 267-289, 311-330, 358-375, 385-407, 414-436 and 446-465
862962013622	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013623	HMMPfam hit to PF02554, Carbon starvation protein CstA, score 1.2e-45
862962013624	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013625	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
862962013626	Signal peptide predicted for BF638R3188 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 46 and 47
862962013627	HMMPfam hit to PF02638, Uncharacterized BCR, COG1649, score 3.2e-32
862962013628	ABC transporter substrate binding protein; Region: ABC_sub_bind; cl17301
862962013629	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962013630	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962013631	dimer interface [polypeptide binding]; other site
862962013632	phosphorylation site [posttranslational modification]
862962013633	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962013634	ATP binding site [chemical binding]; other site
862962013635	Mg2+ binding site [ion binding]; other site
862962013636	G-X-G motif; other site
862962013637	Signal peptide predicted for BF638R3189 by SignalP 2.0 HMM (Signal peptide probability 0.960) with cleavage site probability 0.879 between residues 25 and 26
862962013638	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013639	1 probable transmembrane helix predicted for BF638R3189 by TMHMM2.0 at aa 358-380
862962013640	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.7e-26
862962013641	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.1e-30
862962013642	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013643	AAA domain; Region: AAA_14; pfam13173
862962013644	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
862962013645	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
862962013646	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013647	Short C-terminal domain; Region: SHOCT; pfam09851
862962013648	Tic20-like protein; Region: Tic20; pfam09685
862962013649	3 probable transmembrane helices predicted for BF638R3192 by TMHMM2.0 at aa 56-78, 99-121 and 148-170
862962013650	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013651	Short C-terminal domain; Region: SHOCT; pfam09851
862962013652	Tic20-like protein; Region: Tic20; pfam09685
862962013653	3 probable transmembrane helices predicted for BF638R3193 by TMHMM2.0 at aa 49-71, 92-114 and 129-151
862962013654	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
862962013655	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
862962013656	dimer interface [polypeptide binding]; other site
862962013657	PYR/PP interface [polypeptide binding]; other site
862962013658	TPP binding site [chemical binding]; other site
862962013659	substrate binding site [chemical binding]; other site
862962013660	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
862962013661	Domain of unknown function; Region: EKR; pfam10371
862962013662	4Fe-4S binding domain; Region: Fer4_6; pfam12837
862962013663	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
862962013664	TPP-binding site [chemical binding]; other site
862962013665	dimer interface [polypeptide binding]; other site
862962013666	HMMPfam hit to PF01855, Pyruvate flavodoxin/ferredoxin oxidoredu, score 2.7e-114
862962013667	HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoredu, score 9.8e-69
862962013668	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 8.6e-06
862962013669	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962013670	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 5.1e-05
862962013671	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962013672	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 3.7e-100
862962013673	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
862962013674	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
862962013675	HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 1.6e-61
862962013676	Signal peptide predicted for BF638R3196 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.808 between residues 19 and 20
862962013677	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
862962013678	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
862962013679	dimer interface [polypeptide binding]; other site
862962013680	conserved gate region; other site
862962013681	putative PBP binding loops; other site
862962013682	ABC-ATPase subunit interface; other site
862962013683	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.2e-32
862962013684	7 probable transmembrane helices predicted for BF638R3197 by TMHMM2.0 at aa 15-37, 40-59, 64-82, 89-111, 134-156, 212-234 and 238-260
862962013685	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962013686	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
862962013687	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
862962013688	Walker A/P-loop; other site
862962013689	ATP binding site [chemical binding]; other site
862962013690	Q-loop/lid; other site
862962013691	ABC transporter signature motif; other site
862962013692	Walker B; other site
862962013693	D-loop; other site
862962013694	H-loop/switch region; other site
862962013695	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
862962013696	HMMPfam hit to PF00571, CBS domain, score 0.0089
862962013697	HMMPfam hit to PF00571, CBS domain, score 8.2e-05
862962013698	HMMPfam hit to PF00005, ABC transporter, score 8.3e-68
862962013699	PS00211 ABC transporters family signature.
862962013700	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013701	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
862962013702	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
862962013703	DNA binding site [nucleotide binding]
862962013704	active site
862962013705	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferas, score 6.8e-14
862962013706	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
862962013707	Periplasmic binding domain of two-component sensor kinase signaling systems; Region: PBP1_sensor_kinase_like; cd06308
862962013708	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
862962013709	putative ligand binding site [chemical binding]; other site
862962013710	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962013711	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962013712	dimer interface [polypeptide binding]; other site
862962013713	phosphorylation site [posttranslational modification]
862962013714	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962013715	ATP binding site [chemical binding]; other site
862962013716	Mg2+ binding site [ion binding]; other site
862962013717	G-X-G motif; other site
862962013718	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962013719	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962013720	active site
862962013721	phosphorylation site [posttranslational modification]
862962013722	intermolecular recognition site; other site
862962013723	dimerization interface [polypeptide binding]; other site
862962013724	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962013725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962013726	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.4e-13
862962013727	PS00041 Bacterial regulatory proteins, araC family signature.
862962013728	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.075
862962013729	HMMPfam hit to PF00072, Response regulator receiver domain, score 4.5e-34
862962013730	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013731	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.7e-32
862962013732	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1e-11
862962013733	1 probable transmembrane helix predicted for BF638R3200 by TMHMM2.0 at aa 336-355
862962013734	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.0051
862962013735	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013736	Signal peptide predicted for BF638R3200 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.823 between residues 18 and 19
862962013737	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
862962013738	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
862962013739	putative substrate binding site [chemical binding]; other site
862962013740	putative ATP binding site [chemical binding]; other site
862962013741	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.2e-35
862962013742	PS00583 pfkB family of carbohydrate kinases signature 1.
862962013743	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962013744	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
862962013745	putative substrate translocation pore; other site
862962013746	12 probable transmembrane helices predicted for BF638R3202 by TMHMM2.0 at aa 12-31, 46-68, 77-94, 99-121, 134-156, 166-188, 209-231, 251-273, 280-299, 303-325, 338-357 and 362-384
862962013747	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-31
862962013748	Signal peptide predicted for BF638R3202 by SignalP 2.0 HMM (Signal peptide probability 0.734) with cleavage site probability 0.288 between residues 37 and 38
862962013749	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
862962013750	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
862962013751	substrate binding [chemical binding]; other site
862962013752	active site
862962013753	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
862962013754	HMMPfam hit to PF00251, Glycosyl hydrolases family, score 2.6e-101
862962013755	Signal peptide predicted for BF638R3203 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.493 between residues 27 and 28
862962013756	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013757	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962013758	PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
862962013759	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962013760	Signal peptide predicted for BF638R3204 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.967 between residues 44 and 45
862962013761	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
862962013762	non-specific DNA binding site [nucleotide binding]; other site
862962013763	salt bridge; other site
862962013764	sequence-specific DNA binding site [nucleotide binding]; other site
862962013765	HMMPfam hit to PF01381, Helix-turn-helix, score 9.5e-06
862962013766	Signal peptide predicted for BF638R3206 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.933 between residues 21 and 22
862962013767	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013768	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013769	Signal peptide predicted for BF638R3207 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.631 between residues 19 and 20
862962013770	glucose/galactose transporter; Region: gluP; TIGR01272
862962013771	L-fucose transporter; Provisional; Region: PRK10133; cl17665
862962013772	12 probable transmembrane helices predicted for BF638R3208 by TMHMM2.0 at aa 13-35, 50-68, 89-111, 126-148, 169-191, 201-220, 251-270, 285-302, 315-332, 336-355, 367-389 and 394-416
862962013773	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.5e-11
862962013774	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
862962013775	dimer interface [polypeptide binding]; other site
862962013776	FMN binding site [chemical binding]; other site
862962013777	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
862962013778	dimer interface [polypeptide binding]; other site
862962013779	HMMPfam hit to PF00881, Nitroreductase family, score 7e-15
862962013780	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
862962013781	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
862962013782	potential catalytic triad [active]
862962013783	conserved cys residue [active]
862962013784	HMMPfam hit to PF01965, DJ-1/PfpI family, score 2.6e-20
862962013785	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
862962013786	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
862962013787	active site
862962013788	nucleophile elbow; other site
862962013789	HMMPfam hit to PF01734, Patatin-like phospholipase, score 5.8e-23
862962013790	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013791	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
862962013792	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
862962013793	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
862962013794	12 probable transmembrane helices predicted for BF638R3212 by TMHMM2.0 at aa 7-26, 65-84, 97-119, 129-151, 158-180, 195-214, 227-249, 254-276, 297-319, 347-369, 376-398 and 438-460
862962013795	PS00435 Peroxidases proximal heme-ligand signature.
862962013796	Signal peptide predicted for BF638R3212 by SignalP 2.0 HMM (Signal peptide probability 0.930) with cleavage site probability 0.325 between residues 25 and 26
862962013797	Signal peptide predicted for BF638R3213 by SignalP 2.0 HMM (Signal peptide probability 0.661) with cleavage site probability 0.486 between residues 27 and 28
862962013798	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
862962013799	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
862962013800	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
862962013801	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
862962013802	Kelch motif; Region: Kelch_1; pfam01344
862962013803	Galactose oxidase, central domain; Region: Kelch_3; cl02701
862962013804	HMMPfam hit to PF07646, Kelch motif, score 0.15; HMMPfam hit to PF01344, Kelch motif, score 9.9e-06
862962013805	HMMPfam hit to PF01344, Kelch motif, score 0.00052
862962013806	HMMPfam hit to PF01344, Kelch motif, score 3.2e-07; HMMPfam hit to PF07646, Kelch motif, score 0.24
862962013807	1 probable transmembrane helix predicted for BF638R3214 by TMHMM2.0 at aa 13-35
862962013808	Signal peptide predicted for BF638R3214 by SignalP 2.0 HMM (Signal peptide probability 0.868) with cleavage site probability 0.646 between residues 30 and 31
862962013809	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
862962013810	Signal peptide predicted for BF638R3215 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.495 between residues 22 and 23
862962013811	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013812	Signal peptide predicted for BF638R3216 by SignalP 2.0 HMM (Signal peptide probability 0.929) with cleavage site probability 0.427 between residues 20 and 21
862962013813	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013814	Uncharacterized lipoprotein NlpE involved in copper resistance [Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism]; Region: CutF; COG3015
862962013815	NlpE N-terminal domain; Region: NlpE; pfam04170
862962013816	Signal peptide predicted for BF638R3217 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.627 between residues 25 and 26
862962013817	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013818	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962013819	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1e-16
862962013820	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.7e-15
862962013821	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
862962013822	Signal peptide predicted for BF638R3218 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 22 and 23
862962013823	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962013824	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 6.6e-70
862962013825	12 probable transmembrane helices predicted for BF638R3219 by TMHMM2.0 at aa 13-30, 332-354, 359-381, 391-413, 434-453, 463-485, 525-544, 885-904, 911-930, 934-956, 986-1008 and 1013-1035
862962013826	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013827	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962013828	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962013829	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962013830	Signal peptide predicted for BF638R3220 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.981 between residues 33 and 34
862962013831	1 probable transmembrane helix predicted for BF638R3220 by TMHMM2.0 at aa 13-30
862962013832	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013833	Cupin domain; Region: Cupin_2; cl17218
862962013834	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962013835	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962013836	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.5e-12
862962013837	Peptidase C1-like family; Region: Peptidase_C1_2; cl17447
862962013838	Signal peptide predicted for BF638R3222 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 37 and 38
862962013839	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962013840	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962013841	active site
862962013842	phosphorylation site [posttranslational modification]
862962013843	intermolecular recognition site; other site
862962013844	dimerization interface [polypeptide binding]; other site
862962013845	LytTr DNA-binding domain; Region: LytTR; smart00850
862962013846	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 1.3e-24
862962013847	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.8e-21
862962013848	Histidine kinase; Region: His_kinase; pfam06580
862962013849	HMMPfam hit to PF06580, Histidine kinase, score 6.2e-34
862962013850	4 probable transmembrane helices predicted for BF638R3224 by TMHMM2.0 at aa 13-32, 47-69, 78-100 and 162-184
862962013851	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962013852	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962013853	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962013854	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962013855	Signal peptide predicted for BF638R3226 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.651 between residues 25 and 26
862962013856	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.3e-19
862962013857	HMMPfam hit to PF00593, TonB dependent receptor, score 1.2e-15
862962013858	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962013859	SusD family; Region: SusD; pfam07980
862962013860	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013861	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962013862	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962013863	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
862962013864	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962013865	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962013866	Signal peptide predicted for BF638R3228 by SignalP 2.0 HMM (Signal peptide probability 0.976) with cleavage site probability 0.749 between residues 24 and 25
862962013867	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013868	HMMPfam hit to PF00754, F5/8 type C domain, score 7.8e-07
862962013869	HMMPfam hit to PF00754, F5/8 type C domain, score 0.00017
862962013870	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
862962013871	Ligand binding site [chemical binding]; other site
862962013872	Electron transfer flavoprotein domain; Region: ETF; pfam01012
862962013873	HMMPfam hit to PF01012, Electron transfer flavoprotein beta subunit, score 5.7e-63
862962013874	PS01065 Electron transfer flavoprotein beta-subunit signature.
862962013875	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
862962013876	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
862962013877	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
862962013878	HMMPfam hit to PF00766, Electron transfer flavoprotein alpha subuni, score 5.5e-93
862962013879	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
862962013880	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
862962013881	active site
862962013882	Acyl-CoA dehydrogenase C terminal; Region: AcylCoA_dehyd_C; pfam12186
862962013883	HMMPfam hit to PF02770, Acyl-CoA dehydrogenase, middle domain, score 1.7e-18
862962013884	HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 5e-50
862962013885	PS00073 Acyl-CoA dehydrogenases signature 2.
862962013886	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
862962013887	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962013888	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
862962013889	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
862962013890	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
862962013891	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
862962013892	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962013893	sugar binding site [chemical binding]; other site
862962013894	Signal peptide predicted for BF638R3232 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.990 between residues 19 and 20
862962013895	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 7.2e-86
862962013896	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 6.7e-09
862962013897	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 2.8e-92
862962013898	HMMPfam hit to PF02929, Beta galactosidase small chain, N ter, score 9.9e-11
862962013899	HMMPfam hit to PF02930, Beta galactosidase small chain, C ter, score 1.9e-18
862962013900	HMMPfam hit to PF00754, F5/8 type C domain, score 3.9e-36
862962013901	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
862962013902	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
862962013903	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
862962013904	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
862962013905	HSP70 interaction site [polypeptide binding]; other site
862962013906	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
862962013907	dimer interface [polypeptide binding]; other site
862962013908	HMMPfam hit to PF01556, DnaJ C terminal region, score 5.5e-48
862962013909	HMMPfam hit to PF00226, DnaJ domain, score 2.8e-40
862962013910	PS00636 Nt-dnaJ domain signature.
862962013911	PAS domain S-box; Region: sensory_box; TIGR00229
862962013912	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
862962013913	putative active site [active]
862962013914	heme pocket [chemical binding]; other site
862962013915	PAS domain; Region: PAS_9; pfam13426
862962013916	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962013917	dimer interface [polypeptide binding]; other site
862962013918	phosphorylation site [posttranslational modification]
862962013919	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962013920	ATP binding site [chemical binding]; other site
862962013921	Mg2+ binding site [ion binding]; other site
862962013922	G-X-G motif; other site
862962013923	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.4e-36
862962013924	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
862962013925	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.5e-23
862962013926	1 probable transmembrane helix predicted for BF638R3235 by TMHMM2.0 at aa 75-97
862962013927	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
862962013928	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
862962013929	Sulfatase; Region: Sulfatase; pfam00884
862962013930	HMMPfam hit to PF00884, Sulfatase, score 5.6e-55
862962013931	5 probable transmembrane helices predicted for BF638R3236 by TMHMM2.0 at aa 29-46, 50-72, 79-101, 129-151 and 168-185
862962013932	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962013933	Signal peptide predicted for BF638R3237 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.856 between residues 32 and 33
862962013935	Signal peptide predicted for BF638R3238 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 19 and 20
862962013936	PS00092 N-6 Adenine-specific DNA methylases signature.
862962013937	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
862962013938	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
862962013939	tetramer interface [polypeptide binding]; other site
862962013940	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962013941	catalytic residue [active]
862962013942	HMMPfam hit to PF01212, Beta-eliminating lyase, score 1.1e-52
862962013943	2 probable transmembrane helices predicted for BF638R3241 by TMHMM2.0 at aa 52-74 and 94-113
862962013944	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962013945	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962013946	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962013947	DNA binding residues [nucleotide binding]
862962013948	HMMPfam hit to PF04545, Sigma-70, region, score 1.9e-09
862962013949	HMMPfam hit to PF04542, Sigma-70 region, score 1.2e-14
862962013950	PS01063 Sigma-70 factors ECF subfamily signature.
862962013951	3 probable transmembrane helices predicted for BF638R3243 by TMHMM2.0 at aa 4-26, 72-94 and 109-131
862962013952	PS00657 Fork head domain signature 1.
862962013953	Protein of unknown function (DUF2582); Region: DUF2582; pfam10771
862962013954	pyruvate dehydrogenase; Provisional; Region: PRK06546
862962013955	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
862962013956	PYR/PP interface [polypeptide binding]; other site
862962013957	dimer interface [polypeptide binding]; other site
862962013958	tetramer interface [polypeptide binding]; other site
862962013959	TPP binding site [chemical binding]; other site
862962013960	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
862962013961	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
862962013962	TPP-binding site [chemical binding]; other site
862962013963	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.8e-49
862962013964	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 1.2e-20
862962013965	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013966	PS00187 Thiamine pyrophosphate enzymes signature.
862962013967	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
862962013968	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
862962013969	HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 1.7e-08
862962013971	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013972	PS00017 ATP/GTP-binding site motif A (P-loop).
862962013973	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013974	Signal peptide predicted for BF638R3249 by SignalP 2.0 HMM (Signal peptide probability 0.805) with cleavage site probability 0.690 between residues 23 and 24
862962013975	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
862962013976	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
862962013977	ring oligomerisation interface [polypeptide binding]; other site
862962013978	ATP/Mg binding site [chemical binding]; other site
862962013979	stacking interactions; other site
862962013980	hinge regions; other site
862962013981	HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 4.7e-190
862962013982	PS00296 Chaperonins cpn60 signature.
862962013983	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
862962013984	oligomerisation interface [polypeptide binding]; other site
862962013985	mobile loop; other site
862962013986	roof hairpin; other site
862962013987	HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 3.3e-48
862962013988	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962013989	Signal peptide predicted for BF638R3252 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.718 between residues 21 and 22
862962013990	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013991	Signal peptide predicted for BF638R3253 by SignalP 2.0 HMM (Signal peptide probability 0.864) with cleavage site probability 0.432 between residues 25 and 26
862962013992	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013993	Signal peptide predicted for BF638R3254 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.785 between residues 19 and 20
862962013994	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013995	Signal peptide predicted for BF638R3256 by SignalP 2.0 HMM (Signal peptide probability 0.786) with cleavage site probability 0.768 between residues 31 and 32
862962013996	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962013997	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962013998	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962013999	ligand binding site [chemical binding]; other site
862962014000	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962014001	Signal peptide predicted for BF638R3258 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.693 between residues 21 and 22
862962014002	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
862962014003	HMMPfam hit to PF03976, Domain of unknown function (DUF344), score 3.7e-78
862962014004	4 probable transmembrane helices predicted for BF638R3260 by TMHMM2.0 at aa 51-70, 75-97, 118-140 and 145-167
862962014005	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962014006	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962014007	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962014008	DNA binding residues [nucleotide binding]
862962014009	HMMPfam hit to PF04542, Sigma-70 region, score 1e-12
862962014010	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
862962014011	Helix-turn-helix domain; Region: HTH_38; pfam13936
862962014012	Homeodomain-like domain; Region: HTH_32; pfam13565
862962014013	Integrase core domain; Region: rve; pfam00665
862962014014	HMMPfam hit to PF00665, Integrase core domain, score 1.6e-26
862962014015	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
862962014016	HMMPfam hit to PF03706, Uncharacterised protein family (UPF0104), score 0.00023
862962014017	8 probable transmembrane helices predicted for BF638R3263 by TMHMM2.0 at aa 15-37, 49-66, 97-116, 128-150, 170-191, 235-257, 272-294 and 315-337
862962014018	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962014019	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
862962014020	putative ADP-binding pocket [chemical binding]; other site
862962014021	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.2e-22
862962014022	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962014023	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962014024	Signal peptide predicted for BF638R3265 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.534 between residues 19 and 20
862962014025	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
862962014026	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962014027	Signal peptide predicted for BF638R3266 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 20 and 21
862962014028	HMMPfam hit to PF00930, Dipeptidyl peptidase IV (DPP IV) N-termi, score 8e-06
862962014029	PS00037 Myb DNA-binding domain repeat signature 1.
862962014030	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014031	HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 2.2e-43
862962014032	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014033	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
862962014034	Helix-turn-helix domain; Region: HTH_38; pfam13936
862962014035	Homeodomain-like domain; Region: HTH_32; pfam13565
862962014036	Integrase core domain; Region: rve; pfam00665
862962014037	HMMPfam hit to PF00665, Integrase core domain, score 1.6e-26
862962014038	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
862962014039	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
862962014040	dimer interface [polypeptide binding]; other site
862962014041	motif 1; other site
862962014042	active site
862962014043	motif 2; other site
862962014044	motif 3; other site
862962014045	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
862962014046	anticodon binding site; other site
862962014047	HMMPfam hit to PF03129, Anticodon binding domain, score 3.4e-13
862962014048	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 3.6e-28
862962014049	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
862962014050	2 probable transmembrane helices predicted for BF638R3270 by TMHMM2.0 at aa 15-37 and 50-69
862962014051	1 probable transmembrane helix predicted for BF638R3272 by TMHMM2.0 at aa 13-32
862962014052	Signal peptide predicted for BF638R3272 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.810 between residues 30 and 31
862962014053	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014054	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
862962014055	HMMPfam hit to PF04298, Putative neutral zinc metallopeptidase, score 9.2e-80
862962014056	4 probable transmembrane helices predicted for BF638R3273 by TMHMM2.0 at aa 5-24, 119-141, 146-168 and 201-223
862962014057	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962014058	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
862962014059	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962014060	HMMPfam hit to PF01120, Alpha-L-fucosidase, score 4.8e-15
862962014061	Signal peptide predicted for BF638R3274 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.679 between residues 20 and 21
862962014062	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
862962014063	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
862962014064	GDP-binding site [chemical binding]; other site
862962014065	ACT binding site; other site
862962014066	IMP binding site; other site
862962014067	HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 2.7e-206
862962014068	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014069	PS00513 Adenylosuccinate synthetase active site.
862962014070	PS01266 Adenylosuccinate synthetase GTP-binding site.
862962014071	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
862962014072	metal binding site 2 [ion binding]; metal-binding site
862962014073	putative DNA binding helix; other site
862962014074	metal binding site 1 [ion binding]; metal-binding site
862962014075	dimer interface [polypeptide binding]; other site
862962014076	structural Zn2+ binding site [ion binding]; other site
862962014077	HMMPfam hit to PF01475, Ferric uptake regulator family, score 3.8e-23
862962014078	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
862962014079	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
862962014080	Signal peptide predicted for BF638R3277 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.901 between residues 34 and 35
862962014081	13 probable transmembrane helices predicted for BF638R3277 by TMHMM2.0 at aa 12-34, 86-105, 117-134, 138-157, 164-181, 186-203, 215-237, 262-284, 297-314, 319-341, 361-380, 385-407 and 414-436
862962014082	HMMPfam hit to PF02366, Dolichyl-phosphate-mannose-protein mannosylt, score 2.4e-05
862962014083	A new structural DNA glycosylase; Region: AlkD_like; cd06561
862962014084	active site
862962014085	Peptidase family M49; Region: Peptidase_M49; pfam03571
862962014086	HMMPfam hit to PF03571, Peptidase family M49, score 1.9e-11
862962014087	Signal peptide predicted for BF638R3279 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.324 between residues 23 and 24
862962014088	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014089	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962014090	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014091	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0012
862962014092	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
862962014093	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962014094	ATP binding site [chemical binding]; other site
862962014095	putative Mg++ binding site [ion binding]; other site
862962014096	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962014097	nucleotide binding region [chemical binding]; other site
862962014098	ATP-binding site [chemical binding]; other site
862962014099	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
862962014100	HRDC domain; Region: HRDC; pfam00570
862962014101	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.4e-32
862962014102	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.6e-30
862962014103	HMMPfam hit to PF00570, HRDC domain, score 4.3e-14
862962014104	TPR repeat; Region: TPR_11; pfam13414
862962014105	TPR repeat; Region: TPR_11; pfam13414
862962014106	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962014107	binding surface
862962014108	TPR motif; other site
862962014109	TPR repeat; Region: TPR_11; pfam13414
862962014110	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962014111	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962014112	binding surface
862962014113	TPR motif; other site
862962014114	TPR repeat; Region: TPR_11; pfam13414
862962014115	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.023; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.21
862962014116	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.03; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.028
862962014117	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.1; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.3
862962014118	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.1e-06; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.8e-05
862962014119	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.04; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.1
862962014120	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 6.5e-05; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00034
862962014121	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.12; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.4
862962014122	1 probable transmembrane helix predicted for BF638R3284 by TMHMM2.0 at aa 20-39
862962014123	Signal peptide predicted for BF638R3284 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.805 between residues 35 and 36
862962014124	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
862962014125	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
862962014126	dimer interface [polypeptide binding]; other site
862962014127	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962014128	catalytic residue [active]
862962014129	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962014130	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.5e-116
862962014131	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
862962014132	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
862962014133	Sulfatase; Region: Sulfatase; pfam00884
862962014134	5 probable transmembrane helices predicted for BF638R3286 by TMHMM2.0 at aa 12-34, 54-73, 86-108, 133-155 and 167-189
862962014135	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014136	HMMPfam hit to PF00884, Sulfatase, score 7.3e-28
862962014137	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
862962014138	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
862962014139	active site
862962014140	4 probable transmembrane helices predicted for BF638R3287 by TMHMM2.0 at aa 31-53, 139-158, 162-184 and 201-220
862962014141	HMMPfam hit to PF01569, PAP2 superfamily, score 1.1e-17
862962014142	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
862962014143	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962014144	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.6e-10
862962014145	HMMPfam hit to PF00593, TonB dependent receptor, score 4.5e-14
862962014146	Signal peptide predicted for BF638R3289 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.515 between residues 38 and 39
862962014147	1 probable transmembrane helix predicted for BF638R3289 by TMHMM2.0 at aa 20-42
862962014148	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962014149	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962014150	SusD family; Region: SusD; pfam07980
862962014151	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014152	Signal peptide predicted for BF638R3290 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.720 between residues 19 and 20
862962014153	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962014154	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014155	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962014156	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962014157	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962014158	HMMPfam hit to PF00593, TonB dependent receptor, score 6.4e-24
862962014159	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962014160	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 8.7e-23
862962014161	Signal peptide predicted for BF638R3291 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.919 between residues 39 and 40
862962014162	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962014163	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
862962014164	putative NAD(P) binding site [chemical binding]; other site
862962014165	active site
862962014166	putative substrate binding site [chemical binding]; other site
862962014167	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 9.6e-106
862962014168	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
862962014169	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
862962014170	11 probable transmembrane helices predicted for BF638R3295 by TMHMM2.0 at aa 16-35, 88-110, 131-153, 177-199, 212-234, 268-290, 302-319, 323-341, 348-370, 385-404 and 411-433
862962014171	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014172	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014173	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; cl01627
862962014174	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; cl01627
862962014175	7 probable transmembrane helices predicted for BF638R3296 by TMHMM2.0 at aa 5-24, 36-58, 62-79, 91-108, 123-145, 157-179 and 183-202
862962014176	HMMPfam hit to PF07578, Lipid A Biosynthesis N-terminal domain, score 1.6e-22
862962014177	HMMPfam hit to PF07578, Lipid A Biosynthesis N-terminal domain, score 4.7e-18
862962014178	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962014179	active site
862962014180	HMMPfam hit to PF00535, Glycosyl transferase, score 7.8e-17
862962014181	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
862962014182	tartrate dehydrogenase; Region: TTC; TIGR02089
862962014183	HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 1.8e-152
862962014184	PS00470 Isocitrate and isopropylmalate dehydrogenases signature.
862962014185	(R)-citramalate synthase; Provisional; Region: PRK09389
862962014186	Leptospira interrogans citramalate synthase (CMS) and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_CMS; cd07945
862962014187	active site
862962014188	catalytic residues [active]
862962014189	metal binding site [ion binding]; metal-binding site
862962014190	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
862962014191	HMMPfam hit to PF00682, HMGL-like, score 3.9e-40
862962014192	PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1.
862962014193	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
862962014194	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
862962014195	substrate binding site [chemical binding]; other site
862962014196	HMMPfam hit to PF00694, Aconitase C-terminal domain, score 9.6e-38
862962014197	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
862962014198	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
862962014199	substrate binding site [chemical binding]; other site
862962014200	ligand binding site [chemical binding]; other site
862962014201	HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 2.1e-196
862962014202	PS01244 Aconitase family signature 2.
862962014203	2-isopropylmalate synthase; Validated; Region: PRK00915
862962014204	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
862962014205	active site
862962014206	catalytic residues [active]
862962014207	metal binding site [ion binding]; metal-binding site
862962014208	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
862962014209	HMMPfam hit to PF00682, HMGL-like, score 9.5e-115
862962014210	PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2.
862962014211	PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1.
862962014212	Signal peptide predicted for BF638R3303 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.545 between residues 32 and 33
862962014213	1 probable transmembrane helix predicted for BF638R3303 by TMHMM2.0 at aa 5-24
862962014214	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014215	2 probable transmembrane helices predicted for BF638R3304 by TMHMM2.0 at aa 36-53 and 79-97
862962014216	DPS-like protein, ferritin-like diiron-binding domain; Region: DPSL; cd01052
862962014217	Ferritin-like domain; Region: Ferritin; pfam00210
862962014218	diiron binding motif [ion binding]; other site
862962014219	HMMPfam hit to PF00210, Ferritin-like domain, score 1.2e-12
862962014220	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
862962014221	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
862962014222	tandem repeat interface [polypeptide binding]; other site
862962014223	oligomer interface [polypeptide binding]; other site
862962014224	active site residues [active]
862962014225	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
862962014226	tandem repeat interface [polypeptide binding]; other site
862962014227	oligomer interface [polypeptide binding]; other site
862962014228	active site residues [active]
862962014229	1 probable transmembrane helix predicted for BF638R3306 by TMHMM2.0 at aa 12-34
862962014230	HMMPfam hit to PF01343, Peptidase family S49, score 5.4e-34
862962014231	HMMPfam hit to PF01343, Peptidase family S49, score 1.1e-63
862962014232	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
862962014233	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
862962014234	HMMPfam hit to PF02606, Tetraacyldisaccharide-1-P 4'-kinase, score 1.7e-20
862962014235	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014236	purine nucleoside phosphorylase; Provisional; Region: PRK08202
862962014237	HMMPfam hit to PF00896, Phosphorylase family, score 2.6e-89
862962014238	thiamine monophosphate kinase; Provisional; Region: PRK05731
862962014239	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
862962014240	ATP binding site [chemical binding]; other site
862962014241	dimerization interface [polypeptide binding]; other site
862962014242	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 0.018
862962014243	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962014244	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962014245	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962014246	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962014247	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.9e-09
862962014248	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
862962014249	dimer interface [polypeptide binding]; other site
862962014250	PS00962 Ribosomal protein S2 signature 1.
862962014251	Predicted periplasmic protein (DUF2271); Region: DUF2271; cl17856
862962014252	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014253	Signal peptide predicted for BF638R3315 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.501 between residues 19 and 20
862962014254	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962014255	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962014256	non-specific DNA binding site [nucleotide binding]; other site
862962014257	salt bridge; other site
862962014258	sequence-specific DNA binding site [nucleotide binding]; other site
862962014259	HMMPfam hit to PF01381, Helix-turn-helix, score 4.4e-09
862962014260	SIR2-like domain; Region: SIR2_2; pfam13289
862962014261	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
862962014262	5' RNA guide strand anchoring site; other site
862962014263	active site
862962014264	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
862962014265	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962014266	motif II; other site
862962014267	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.4e-12
862962014268	maltose O-acetyltransferase; Provisional; Region: PRK10092
862962014269	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
862962014270	active site
862962014271	substrate binding site [chemical binding]; other site
862962014272	trimer interface [polypeptide binding]; other site
862962014273	CoA binding site [chemical binding]; other site
862962014274	PS00101 Hexapeptide-repeat containing-transferases signature.
862962014275	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.14
862962014276	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.5
862962014277	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.17
862962014278	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 18
862962014279	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
862962014280	putative FMN binding site [chemical binding]; other site
862962014281	HMMPfam hit to PF00881, Nitroreductase family, score 7.7e-34
862962014282	PS00904 Protein prenyltransferases alpha subunit repeat signature.
862962014283	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
862962014284	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962014285	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014286	HMMPfam hit to PF07883, Cupin domain, score 0.004
862962014287	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.1e-05
862962014288	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.9e-07
862962014289	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962014290	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962014291	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962014292	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
862962014293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962014294	ATP binding site [chemical binding]; other site
862962014295	Mg2+ binding site [ion binding]; other site
862962014296	G-X-G motif; other site
862962014297	Response regulator receiver domain; Region: Response_reg; pfam00072
862962014298	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962014299	active site
862962014300	phosphorylation site [posttranslational modification]
862962014301	intermolecular recognition site; other site
862962014302	dimerization interface [polypeptide binding]; other site
862962014303	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962014304	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014305	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 7.1e-08
862962014306	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.022
862962014307	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-25
862962014308	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.1e-25
862962014309	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.5e-09
862962014310	2 probable transmembrane helices predicted for BF638R3328 by TMHMM2.0 at aa 7-29 and 782-804
862962014311	HMMPfam hit to PF07495, Two component regulator three Y motif, score 2.6e-10
862962014312	HMMPfam hit to PF07494, Two component regulator propeller, score 0.099
862962014313	HMMPfam hit to PF07494, Two component regulator propeller, score 7.5
862962014314	HMMPfam hit to PF07494, Two component regulator propeller, score 11
862962014315	HMMPfam hit to PF07494, Two component regulator propeller, score 11
862962014316	HMMPfam hit to PF07494, Two component regulator propeller, score 6.2
862962014317	HMMPfam hit to PF07494, Two component regulator propeller, score 0.049
862962014318	HMMPfam hit to PF07494, Two component regulator propeller, score 0.45
862962014319	HMMPfam hit to PF07494, Two component regulator propeller, score 6.8
862962014320	HMMPfam hit to PF07494, Two component regulator propeller, score 32
862962014321	HMMPfam hit to PF07494, Two component regulator propeller, score 0.029
862962014322	Signal peptide predicted for BF638R3328 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 27 and 28
862962014323	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
862962014324	Signal peptide predicted for BF638R3329 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 19 and 20
862962014325	Domain of unknown function (DUF303); Region: DUF303; pfam03629
862962014326	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
862962014327	Domain of unknown function (DUF303); Region: DUF303; pfam03629
862962014328	Signal peptide predicted for BF638R3330 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 20 and 21
862962014329	1 probable transmembrane helix predicted for BF638R3330 by TMHMM2.0 at aa 7-29
862962014330	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 2.5e-05
862962014331	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
862962014332	Signal peptide predicted for BF638R3331 by SignalP 2.0 HMM (Signal peptide probability 0.607) with cleavage site probability 0.598 between residues 18 and 19
862962014333	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
862962014334	active site
862962014335	Signal peptide predicted for BF638R3332 by SignalP 2.0 HMM (Signal peptide probability 0.759) with cleavage site probability 0.554 between residues 28 and 29
862962014336	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014337	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962014338	SusD family; Region: SusD; pfam07980
862962014339	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014340	Signal peptide predicted for BF638R3333 by SignalP 2.0 HMM (Signal peptide probability 0.624) with cleavage site probability 0.272 between residues 18 and 19
862962014341	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962014342	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014343	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962014344	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962014345	HMMPfam hit to PF00593, TonB dependent receptor, score 5.5e-08
862962014346	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.9e-20
862962014347	1 probable transmembrane helix predicted for BF638R3334 by TMHMM2.0 at aa 7-26
862962014348	Signal peptide predicted for BF638R3334 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.985 between residues 24 and 25
862962014349	Glycosyl hydrolase family 76; Region: Glyco_hydro_76; pfam03663
862962014350	HMMPfam hit to PF03663, Glycosyl hydrolase family, score 3.8e-07
862962014351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014352	Signal peptide predicted for BF638R3335 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.534 between residues 19 and 20
862962014353	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
862962014354	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
862962014355	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.6e-12
862962014356	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_7; cd13133
862962014357	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962014358	12 probable transmembrane helices predicted for BF638R3337 by TMHMM2.0 at aa 9-28, 43-65, 85-107, 127-149, 156-178, 182-204, 231-253, 273-295, 308-326, 341-363, 376-398 and 402-424
862962014359	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014360	HMMPfam hit to PF01554, MatE, score 3.6e-30
862962014361	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
862962014362	HMMPfam hit to PF07883, Cupin domain, score 6.1e-09
862962014363	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962014364	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
862962014365	ligand binding site [chemical binding]; other site
862962014366	active site
862962014367	UGI interface [polypeptide binding]; other site
862962014368	catalytic site [active]
862962014369	HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 1.6e-71
862962014370	PS00130 Uracil-DNA glycosylase signature.
862962014371	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962014372	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014373	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
862962014374	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 0.0028
862962014375	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 3.8e-12
862962014376	HMMPfam hit to PF06445, Bacterial transcription activator, effect, score 1.5e-45
862962014377	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962014378	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962014379	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962014380	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; pfam09603
862962014381	Signal peptide predicted for BF638R3342 by SignalP 2.0 HMM (Signal peptide probability 0.868) with cleavage site probability 0.740 between residues 29 and 30
862962014382	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014383	Signal peptide predicted for BF638R3343 by SignalP 2.0 HMM (Signal peptide probability 0.847) with cleavage site probability 0.643 between residues 21 and 22
862962014384	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
862962014385	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
862962014386	Hemerythrin-like domain; Region: Hr-like; cd12108
862962014387	Fe binding site [ion binding]; other site
862962014388	HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 6.2e-07
862962014389	HMMPfam hit to PF01814, Hemerythrin HHE cation binding domain, score 0.0012
862962014390	NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.  Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450
862962014391	putative active site [active]
862962014392	putative catalytic site [active]
862962014393	HMMPfam hit to PF01575, MaoC like domain, score 9.9e-14
862962014394	Protein of unknown function, DUF393; Region: DUF393; pfam04134
862962014395	HMMPfam hit to PF04134, Protein of unknown function, DUF393, score 1.9e-28
862962014396	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
862962014397	Signal peptide predicted for BF638R3348 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.580 between residues 48 and 49
862962014398	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014399	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
862962014400	classical (c) SDRs; Region: SDR_c; cd05233
862962014401	NAD(P) binding site [chemical binding]; other site
862962014402	active site
862962014403	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.9e-61
862962014404	PS00061 Short-chain dehydrogenases/reductases family signature.
862962014405	Electron transfer DM13; Region: DM13; cl02735
862962014406	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962014407	1 probable transmembrane helix predicted for BF638R3351 by TMHMM2.0 at aa 7-29
862962014408	Signal peptide predicted for BF638R3351 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.859 between residues 26 and 27
862962014409	Signal peptide predicted for BF638R3353 by SignalP 2.0 HMM (Signal peptide probability 0.942) with cleavage site probability 0.568 between residues 25 and 26
862962014410	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014411	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014412	Signal peptide predicted for BF638R3354 by SignalP 2.0 HMM (Signal peptide probability 0.926) with cleavage site probability 0.257 between residues 38 and 39
862962014413	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014414	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962014415	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962014416	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
862962014417	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014418	Signal peptide predicted for BF638R3356 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.361 between residues 34 and 35
862962014419	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014420	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962014421	Signal peptide predicted for BF638R3357 by SignalP 2.0 HMM (Signal peptide probability 0.794) with cleavage site probability 0.751 between residues 28 and 29
862962014422	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014423	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
862962014424	Signal peptide predicted for BF638R3358 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.706 between residues 22 and 23
862962014425	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014426	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962014427	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014428	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.081
862962014429	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.011
862962014430	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962014431	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
862962014432	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962014433	active site
862962014434	DNA binding site [nucleotide binding]
862962014435	Int/Topo IB signature motif; other site
862962014436	HMMPfam hit to PF00589, Phage integrase family, score 6.4e-06
862962014437	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014438	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962014439	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.24
862962014440	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.14
862962014441	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
862962014442	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
862962014443	active site
862962014444	HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 1.2e-79
862962014445	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962014446	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962014447	catalytic residues [active]
862962014448	PS00194 Thioredoxin family active site.
862962014449	PS00190 Cytochrome c family heme-binding site signature.
862962014450	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014451	Signal peptide predicted for BF638R3363 by SignalP 2.0 HMM (Signal peptide probability 0.897) with cleavage site probability 0.508 between residues 19 and 20
862962014452	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
862962014453	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
862962014454	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
862962014455	TrkA-C domain; Region: TrkA_C; pfam02080
862962014456	TrkA-C domain; Region: TrkA_C; pfam02080
862962014457	HMMPfam hit to PF02080, TrkA-C domain, score 3.4e-12
862962014458	HMMPfam hit to PF02080, TrkA-C domain, score 5.3e-13
862962014459	15 probable transmembrane helices predicted for BF638R3364 by TMHMM2.0 at aa 6-25, 32-51, 61-80, 87-109, 119-138, 151-173, 188-210, 222-244, 274-293, 300-322, 358-380, 427-449, 459-481, 502-524 and 529-548
862962014460	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
862962014461	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962014462	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
862962014463	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
862962014464	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.2e-49
862962014465	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 4.4e-107
862962014466	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
862962014467	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962014468	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 4.8e-58
862962014469	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962014470	carboxyltransferase (CT) interaction site; other site
862962014471	biotinylation site [posttranslational modification]; other site
862962014472	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 6e-14
862962014473	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
862962014474	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
862962014475	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
862962014476	HMMPfam hit to PF01039, Carboxyl transferase domain, score 8.7e-285
862962014477	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962014478	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014479	Isochorismatase family; Region: Isochorismatase; pfam00857
862962014480	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
862962014481	catalytic triad [active]
862962014482	conserved cis-peptide bond; other site
862962014483	HMMPfam hit to PF00857, Isochorismatase family, score 4e-06
862962014484	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
862962014485	Beta-lactamase; Region: Beta-lactamase; pfam00144
862962014486	Domain of unknown function DUF302; Region: DUF302; cl01364
862962014487	Signal peptide predicted for BF638R3369 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.858 between residues 19 and 20
862962014488	PS00850 Glycine radical signature.
862962014489	HMMPfam hit to PF03625, Domain of unknown function DUF302, score 2e-27
862962014490	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
862962014491	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
862962014492	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
862962014493	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
862962014494	active site
862962014495	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 2.6e-119
862962014496	PS00487 IMP dehydrogenase / GMP reductase signature.
862962014497	HMMPfam hit to PF00571, CBS domain, score 0.0021
862962014498	HMMPfam hit to PF00571, CBS domain, score 0.00011
862962014499	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2350
862962014500	HMMPfam hit to PF03795, YCII-related domain, score 1.8e-18
862962014501	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962014502	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962014503	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.2e-09
862962014504	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962014505	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962014506	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962014507	Signal peptide predicted for BF638R3375 by SignalP 2.0 HMM (Signal peptide probability 0.964) with cleavage site probability 0.354 between residues 25 and 26
862962014508	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014509	HMMPfam hit to PF00529, HlyD family secretion protein, score 2.7e-26
862962014510	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962014511	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962014512	12 probable transmembrane helices predicted for BF638R3376 by TMHMM2.0 at aa 11-33, 335-357, 364-386, 392-414, 435-457, 472-494, 540-557, 870-892, 899-921, 925-947, 974-996 and 1006-1028
862962014513	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
862962014514	Signal peptide predicted for BF638R3377 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.628 between residues 21 and 22
862962014515	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014516	HMMPfam hit to PF02321, Outer membrane efflux protein, score 4.2e-24
862962014517	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2e-33
862962014518	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
862962014519	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
862962014520	homodimer interface [polypeptide binding]; other site
862962014521	substrate-cofactor binding pocket; other site
862962014522	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962014523	catalytic residue [active]
862962014524	HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 2.3e-187
862962014525	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
862962014526	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
862962014527	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
862962014528	active site
862962014529	metal binding site [ion binding]; metal-binding site
862962014530	Signal peptide predicted for BF638R3379 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.517 between residues 21 and 22
862962014531	HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 3.8e-05
862962014532	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
862962014533	HMMPfam hit to PF02574, Homocysteine S-methyltransferase, score 1.4e-06
862962014534	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014535	8 probable transmembrane helices predicted for BF638R3381 by TMHMM2.0 at aa 13-30, 60-77, 84-106, 121-140, 171-193, 217-239, 246-268 and 283-305
862962014536	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014537	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014538	1 probable transmembrane helix predicted for BF638R3383 by TMHMM2.0 at aa 68-90
862962014539	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014540	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962014541	FtsX-like permease family; Region: FtsX; pfam02687
862962014542	FtsX-like permease family; Region: FtsX; pfam02687
862962014543	Signal peptide predicted for BF638R3386 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.382 between residues 37 and 38
862962014544	8 probable transmembrane helices predicted for BF638R3386 by TMHMM2.0 at aa 21-43, 272-294, 314-336, 364-386, 407-429, 646-668, 689-711 and 731-753
862962014545	HMMPfam hit to PF02687, Predicted permease, score 1.1e-10
862962014546	HMMPfam hit to PF02687, Predicted permease, score 6.4e-07
862962014547	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
862962014548	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
862962014549	motif II; other site
862962014550	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.4e-14
862962014551	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962014552	Tandemly repeated domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like; cl17916
862962014553	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962014554	Signal peptide predicted for BF638R3388 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.391 between residues 21 and 22
862962014555	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014556	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014557	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962014558	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014559	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962014560	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.016
862962014561	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
862962014562	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962014563	Heavy-metal-associated domain; Region: HMA; pfam00403
862962014564	HMMPfam hit to PF00403, Heavy-metal-associated domain, score 0.0062
862962014565	Signal peptide predicted for BF638R3392 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.743 between residues 39 and 40
862962014566	1 probable transmembrane helix predicted for BF638R3392 by TMHMM2.0 at aa 13-30
862962014567	Outer membrane efflux protein; Region: OEP; pfam02321
862962014568	Outer membrane efflux protein; Region: OEP; pfam02321
862962014569	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0013
862962014570	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.00077
862962014571	Signal peptide predicted for BF638R3393 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.743 between residues 27 and 28
862962014572	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962014573	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962014574	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 2.4e-159
862962014575	16 probable transmembrane helices predicted for BF638R3394 by TMHMM2.0 at aa 13-35, 361-383, 390-412, 416-438, 470-492, 507-529, 536-555, 559-576, 583-600, 615-637, 644-666, 1045-1062, 1069-1091, 1111-1133, 1170-1189 and 1204-1226
862962014576	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014577	Signal peptide predicted for BF638R3396 by SignalP 2.0 HMM (Signal peptide probability 0.973) with cleavage site probability 0.372 between residues 34 and 35
862962014578	Signal peptide predicted for BF638R3395 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.453 between residues 32 and 33
862962014579	1 probable transmembrane helix predicted for BF638R3396 by TMHMM2.0 at aa 7-29
862962014580	1 probable transmembrane helix predicted for BF638R3395 by TMHMM2.0 at aa 4-26
862962014581	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
862962014582	N-acetyl-D-glucosamine binding site [chemical binding]; other site
862962014583	catalytic residue [active]
862962014584	HMMPfam hit to PF01464, Transglycosylase SLT domain, score 3.2e-20
862962014585	PS00922 Prokaryotic transglycosylases signature.
862962014586	Ion transport protein; Region: Ion_trans; pfam00520
862962014587	Ion channel; Region: Ion_trans_2; pfam07885
862962014588	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
862962014589	6 probable transmembrane helices predicted for BF638R3398 by TMHMM2.0 at aa 34-52, 57-79, 94-116, 160-182, 197-219 and 221-243
862962014590	HMMPfam hit to PF00520, Ion transport protein, score 2.9e-36
862962014591	HMMPfam hit to PF07885, Ion channel, score 1.5e-20
862962014592	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
862962014593	Part of AAA domain; Region: AAA_19; pfam13245
862962014594	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
862962014595	AAA domain; Region: AAA_12; pfam13087
862962014596	Protein of unknown function (DUF3320); Region: DUF3320; pfam11784
862962014597	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014598	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014599	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014600	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
862962014601	4 probable transmembrane helices predicted for BF638R3400 by TMHMM2.0 at aa 5-24, 29-51, 58-77 and 101-118
862962014602	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014603	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
862962014604	MgtC family; Region: MgtC; pfam02308
862962014605	5 probable transmembrane helices predicted for BF638R3401 by TMHMM2.0 at aa 5-23, 36-55, 70-89, 96-113 and 117-139
862962014606	HMMPfam hit to PF02308, MgtC family, score 1.2e-48
862962014607	probable DNA metabolism protein; Region: SAM_7_link_chp; TIGR03915
862962014608	putative DNA modification/repair radical SAM protein; Region: rSAM_link_UDG; TIGR03916
862962014609	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962014610	FeS/SAM binding site; other site
862962014611	HMMPfam hit to PF04055, Radical SAM superfamily, score 0.00083
862962014612	PS00260 Glucagon / GIP / secretin / VIP family signature.
862962014613	Phage X family; Region: Phage_X; cl11585
862962014614	WYL domain; Region: WYL; pfam13280
862962014615	methionine sulfoxide reductase A; Provisional; Region: PRK14054
862962014616	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
862962014617	SelR domain; Region: SelR; pfam01641
862962014618	Signal peptide predicted for BF638R3405 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.796 between residues 23 and 24
862962014619	1 probable transmembrane helix predicted for BF638R3405 by TMHMM2.0 at aa 7-29
862962014620	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 1.2e-88
862962014621	HMMPfam hit to PF01641, SelR domain, score 1e-90
862962014622	Divergent AAA domain; Region: AAA_4; pfam04326
862962014623	HMMPfam hit to PF04326, Divergent AAA domain, score 5.9e-25
862962014624	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014625	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
862962014626	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
862962014627	9 probable transmembrane helices predicted for BF638R3407 by TMHMM2.0 at aa 7-26, 75-97, 139-158, 171-193, 203-225, 293-315, 335-357, 377-399 and 404-426
862962014628	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014629	HMMPfam hit to PF01235, Sodium:alanine symporter family, score 4.5e-202
862962014630	PS00873 Sodium:alanine symporter family signature.
862962014631	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
862962014632	PS00261 Glycoprotein hormones beta chain signature 1.
862962014633	xanthine permease; Region: pbuX; TIGR03173
862962014634	11 probable transmembrane helices predicted for BF638R3410 by TMHMM2.0 at aa 22-44, 51-68, 88-110, 130-152, 167-186, 199-221, 241-260, 326-348, 353-375, 384-401 and 411-433
862962014635	HMMPfam hit to PF00860, Permease family, score 9.1e-110
862962014636	PS01116 Xanthine/uracil permeases family signature.
862962014637	PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
862962014638	1 probable transmembrane helix predicted for BF638R3411 by TMHMM2.0 at aa 13-32
862962014639	Signal peptide predicted for BF638R3411 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.597 between residues 31 and 32
862962014640	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
862962014641	putative active site [active]
862962014642	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
862962014643	ArsC family; Region: ArsC; pfam03960
862962014644	putative ArsC-like catalytic residues; other site
862962014645	putative TRX-like catalytic residues [active]
862962014646	HMMPfam hit to PF03960, ArsC family, score 4e-38
862962014647	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014648	PS00215 Mitochondrial energy transfer proteins signature.
862962014649	1 probable transmembrane helix predicted for BF638R3414 by TMHMM2.0 at aa 65-87
862962014650	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962014651	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962014652	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962014653	DNA binding residues [nucleotide binding]
862962014654	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-08
862962014655	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
862962014656	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
862962014657	putative acyl-acceptor binding pocket; other site
862962014658	HMMPfam hit to PF01553, Acyltransferase, score 5.3e-07
862962014659	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014660	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
862962014661	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
862962014662	HMMPfam hit to PF01148, Cytidylyltransferase family, score 2.9e-72
862962014663	PS01315 Phosphatidate cytidylyltransferase signature.
862962014664	7 probable transmembrane helices predicted for BF638R3417 by TMHMM2.0 at aa 15-37, 57-79, 121-143, 155-177, 187-209, 230-252 and 256-275
862962014665	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
862962014666	4 probable transmembrane helices predicted for BF638R3418 by TMHMM2.0 at aa 50-72, 122-156, 177-194 and 198-220
862962014667	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014668	von Willebrand factor; Region: vWF_A; pfam12450
862962014669	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
862962014670	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
862962014671	metal ion-dependent adhesion site (MIDAS); other site
862962014672	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
862962014673	Signal peptide predicted for BF638R3419 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.789 between residues 27 and 28
862962014674	HMMPfam hit to PF00092, von Willebrand factor type A domain, score 1.4e-23
862962014675	PS00435 Peroxidases proximal heme-ligand signature.
862962014676	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962014677	Signal peptide predicted for BF638R3420 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.988 between residues 21 and 22
862962014678	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
862962014679	dimer interface [polypeptide binding]; other site
862962014680	pyridoxal binding site [chemical binding]; other site
862962014681	ATP binding site [chemical binding]; other site
862962014682	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
862962014683	HMMPfam hit to PF02589, Uncharacterized ACR, YkgG family COG1556, score 1.4e-06
862962014684	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
862962014685	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
862962014686	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0013
862962014687	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962014688	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0016
862962014689	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962014690	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
862962014691	Cysteine-rich domain; Region: CCG; pfam02754
862962014692	Cysteine-rich domain; Region: CCG; pfam02754
862962014693	HMMPfam hit to PF02754, Cysteine-rich domain, score 1.7e-09
862962014694	HMMPfam hit to PF02754, Cysteine-rich domain, score 1.2e-10
862962014695	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
862962014696	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962014697	FeS/SAM binding site; other site
862962014698	HMMPfam hit to PF04055, Radical SAM superfamily, score 3.1e-07
862962014699	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
862962014700	active site
862962014701	HMMPfam hit to PF01242, 6-pyruvoyl tetrahydropterin synthase, score 4.5e-08
862962014702	nucleosidase; Provisional; Region: PRK05634
862962014703	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
862962014704	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
862962014705	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962014706	HMMPfam hit to PF01757, Acyltransferase family, score 0.0005
862962014707	10 probable transmembrane helices predicted for BF638R3429 by TMHMM2.0 at aa 13-35, 50-72, 92-114, 155-174, 186-208, 223-242, 254-276, 286-308, 329-348 and 358-380
862962014708	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
862962014709	Signal peptide predicted for BF638R3430 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 21 and 22
862962014710	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
862962014711	HMMPfam hit to PF03932, CutC family, score 2.2e-102
862962014712	phosphodiesterase; Provisional; Region: PRK12704
862962014713	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962014714	Zn2+ binding site [ion binding]; other site
862962014715	Mg2+ binding site [ion binding]; other site
862962014716	HMMPfam hit to PF01966, HD domain, score 3.2e-24
862962014717	HMMPfam hit to PF00013, KH domain, score 1.3e-09
862962014718	1 probable transmembrane helix predicted for BF638R3432 by TMHMM2.0 at aa 5-27
862962014719	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014720	Cell division protein ZapA; Region: ZapA; pfam05164
862962014721	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
862962014722	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
862962014723	Malic enzyme, N-terminal domain; Region: malic; pfam00390
862962014724	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
862962014725	putative NAD(P) binding site [chemical binding]; other site
862962014726	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
862962014727	HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 7.1e-81
862962014728	HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 1.7e-116
862962014729	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014730	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 2.1e-57
862962014731	glutamate dehydrogenase; Provisional; Region: PRK14031
862962014732	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
862962014733	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
862962014734	NAD(P) binding site [chemical binding]; other site
862962014735	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 3.2e-82
862962014736	PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
862962014737	HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 1.4e-140
862962014738	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962014739	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962014740	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962014741	DNA binding residues [nucleotide binding]
862962014742	HMMPfam hit to PF04542, Sigma-70 region, score 1.2e-11
862962014743	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962014744	FecR protein; Region: FecR; pfam04773
862962014745	1 probable transmembrane helix predicted for BF638R3438 by TMHMM2.0 at aa 80-102
862962014746	HMMPfam hit to PF04773, FecR protein, score 2.6e-20
862962014747	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962014748	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962014749	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014750	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962014751	Signal peptide predicted for BF638R3439 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 25 and 26
862962014752	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 2.4e-08
862962014753	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2e-18
862962014754	HMMPfam hit to PF00593, TonB dependent receptor, score 5.1e-20
862962014755	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
862962014756	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962014757	Signal peptide predicted for BF638R3440 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.959 between residues 29 and 30
862962014758	Endo-beta-N-acetylglucosaminidases are bacterial chitinases that hydrolyze the chitin core of various asparagine (N)-linked glycans and glycoproteins. The endo-beta-N-acetylglucosaminidases have a glycosyl hydrolase family 18 (GH18) catalytic domain; Region: GH18_EndoS-like; cd06542
862962014759	active site
862962014760	Signal peptide predicted for BF638R3441 by SignalP 2.0 HMM (Signal peptide probability 0.832) with cleavage site probability 0.788 between residues 21 and 22
862962014761	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014762	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
862962014763	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
862962014764	Signal peptide predicted for BF638R3442 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.832 between residues 27 and 28
862962014765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014766	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
862962014767	Signal peptide predicted for BF638R3443 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.776 between residues 25 and 26
862962014768	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014769	1 probable transmembrane helix predicted for BF638R3444 by TMHMM2.0 at aa 5-27
862962014770	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
862962014771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962014772	non-specific DNA binding site [nucleotide binding]; other site
862962014773	salt bridge; other site
862962014774	sequence-specific DNA binding site [nucleotide binding]; other site
862962014775	HMMPfam hit to PF01381, Helix-turn-helix, score 3.1e-11
862962014776	Signal peptide predicted for BF638R3446 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.618 between residues 27 and 28
862962014777	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014778	AAA domain; Region: AAA_21; pfam13304
862962014779	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014780	1 probable transmembrane helix predicted for BF638R3449 by TMHMM2.0 at aa 9-31
862962014781	Signal peptide predicted for BF638R3450 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.658 between residues 21 and 22
862962014782	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014783	Signal peptide predicted for BF638R3451 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.742 between residues 20 and 21
862962014784	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014785	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
862962014786	Signal peptide predicted for BF638R3452 by SignalP 2.0 HMM (Signal peptide probability 0.842) with cleavage site probability 0.367 between residues 22 and 23
862962014787	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014788	Signal peptide predicted for BF638R3453 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.963 between residues 18 and 19
862962014789	Fibronectin type 3 domain; Region: FN3; smart00060
862962014790	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
862962014791	Signal peptide predicted for BF638R3454 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.925 between residues 21 and 22
862962014792	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014793	Signal peptide predicted for BF638R3455 by SignalP 2.0 HMM (Signal peptide probability 0.844) with cleavage site probability 0.614 between residues 27 and 28
862962014794	Signal peptide predicted for BF638R3456 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.266 between residues 23 and 24
862962014795	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014796	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962014797	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962014798	intermolecular recognition site; other site
862962014799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
862962014800	active site
862962014801	phosphorylation site [posttranslational modification]
862962014802	intermolecular recognition site; other site
862962014803	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
862962014804	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962014805	glutamate dehydrogenase; Provisional; Region: PRK14030
862962014806	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
862962014807	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
862962014808	NAD(P) binding site [chemical binding]; other site
862962014809	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 3.6e-82
862962014810	PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
862962014811	HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 6.8e-135
862962014812	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014813	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
862962014814	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
862962014815	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
862962014816	active site
862962014817	HMMPfam hit to PF00557, metallopeptidase family M24, score 6e-21
862962014818	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962014819	binding surface
862962014820	TPR motif; other site
862962014821	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962014822	CARDB; Region: CARDB; pfam07705
862962014823	Caspase domain; Region: Peptidase_C14; pfam00656
862962014824	HMMPfam hit to PF00656, Caspase domain, score 3.1e-05
862962014825	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014826	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.6
862962014827	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.2
862962014828	Signal peptide predicted for BF638R3461 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.979 between residues 21 and 22
862962014829	FOG: WD40 repeat [General function prediction only]; Region: COG2319
862962014830	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
862962014831	structural tetrad; other site
862962014832	Signal peptide predicted for BF638R3462 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 29 and 30
862962014833	1 probable transmembrane helix predicted for BF638R3463 by TMHMM2.0 at aa 15-37
862962014834	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
862962014835	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
862962014836	active site
862962014837	NTP binding site [chemical binding]; other site
862962014838	metal binding triad [ion binding]; metal-binding site
862962014839	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
862962014840	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962014841	Zn2+ binding site [ion binding]; other site
862962014842	Mg2+ binding site [ion binding]; other site
862962014843	HMMPfam hit to PF01966, HD domain, score 6.6e-08
862962014844	HMMPfam hit to PF01743, Poly A polymerase family, score 1.4e-50
862962014845	Signal peptide predicted for BF638R3465 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.577 between residues 27 and 28
862962014846	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014847	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962014848	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962014849	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962014850	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962014851	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962014852	Signal peptide predicted for BF638R3466 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.987 between residues 19 and 20
862962014853	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.7e-13
862962014854	HMMPfam hit to PF00593, TonB dependent receptor, score 2.8e-09
862962014855	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962014856	SusD family; Region: SusD; pfam07980
862962014857	Signal peptide predicted for BF638R3467 by SignalP 2.0 HMM (Signal peptide probability 0.801) with cleavage site probability 0.358 between residues 31 and 32
862962014858	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014859	Signal peptide predicted for BF638R3468 by SignalP 2.0 HMM (Signal peptide probability 0.740) with cleavage site probability 0.538 between residues 25 and 26
862962014860	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014861	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962014862	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
862962014863	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962014864	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962014865	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962014866	Signal peptide predicted for BF638R3469 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.796 between residues 25 and 26
862962014867	1 probable transmembrane helix predicted for BF638R3469 by TMHMM2.0 at aa 7-26
862962014868	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 7.9e-20
862962014869	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 1.5e-10
862962014870	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 2.6e-19
862962014871	Protein of unknown function, DUF399; Region: DUF399; cl01139
862962014872	HMMPfam hit to PF04187, Protein of unknown function, DUF399, score 8.6e-15
862962014873	Signal peptide predicted for BF638R3470 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 25 and 26
862962014874	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
862962014875	DNA-binding site [nucleotide binding]; DNA binding site
862962014876	RNA-binding motif; other site
862962014877	HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 3.4e-10
862962014878	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
862962014879	similar to PS_3/PS_H lipopolysaccharide biosynthesis locus in BF9343
862962014880	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
862962014881	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 2.1e-104
862962014882	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962014883	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962014884	substrate binding site; other site
862962014885	tetramer interface; other site
862962014886	HMMPfam hit to PF00483, Nucleotidyl transferase, score 9.9e-104
862962014887	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
862962014888	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
862962014889	metal-binding site
862962014890	HMMPfam hit to PF00535, Glycosyl transferase, score 1.3e-31
862962014891	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962014892	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962014893	active site
862962014894	HMMPfam hit to PF00535, Glycosyl transferase, score 2e-28
862962014895	10 probable transmembrane helices predicted for BF638R3477 by TMHMM2.0 at aa 4-23, 30-47, 78-100, 113-135, 155-177, 190-212, 235-257, 269-291, 295-317 and 324-341
862962014896	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962014897	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962014898	HMMPfam hit to PF00534, Glycosyl transferases group, score 2.6e-09
862962014899	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962014900	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
862962014901	metal-binding site
862962014902	HMMPfam hit to PF00535, Glycosyl transferase, score 5.1e-26
862962014903	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962014904	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962014905	active site
862962014906	HMMPfam hit to PF00535, Glycosyl transferase, score 9.5e-40
862962014907	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
862962014908	12 probable transmembrane helices predicted for BF638R3481 by TMHMM2.0 at aa 27-49, 59-81, 100-122, 145-167, 174-192, 202-224, 245-264, 279-301, 322-344, 364-386, 393-415 and 419-441
862962014909	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014910	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
862962014911	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962014912	NAD binding site [chemical binding]; other site
862962014913	homotetramer interface [polypeptide binding]; other site
862962014914	homodimer interface [polypeptide binding]; other site
862962014915	active site
862962014916	substrate binding site [chemical binding]; other site
862962014917	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 1.4e-40
862962014918	Signal peptide predicted for BF638R3482 by SignalP 2.0 HMM (Signal peptide probability 0.776) with cleavage site probability 0.522 between residues 17 and 18
862962014919	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962014920	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962014921	NAD(P) binding site [chemical binding]; other site
862962014922	active site
862962014923	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
862962014924	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
862962014925	NAD binding site [chemical binding]; other site
862962014926	homotetramer interface [polypeptide binding]; other site
862962014927	homodimer interface [polypeptide binding]; other site
862962014928	substrate binding site [chemical binding]; other site
862962014929	active site
862962014930	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 3.6e-13
862962014931	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962014932	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
862962014933	substrate binding site; other site
862962014934	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.4e-10
862962014935	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
862962014936	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962014937	inhibitor-cofactor binding pocket; inhibition site
862962014938	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962014939	catalytic residue [active]
862962014940	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.4e-122
862962014941	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
862962014942	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
862962014943	Mg++ binding site [ion binding]; other site
862962014944	putative catalytic motif [active]
862962014945	substrate binding site [chemical binding]; other site
862962014946	11 probable transmembrane helices predicted for BF638R3487 by TMHMM2.0 at aa 5-27, 50-72, 82-104, 117-134, 140-162, 175-192, 197-219, 228-247, 262-284, 316-335 and 339-356
862962014947	HMMPfam hit to PF00953, Glycosyl transferase, score 1e-23
862962014948	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962014949	Signal peptide predicted for BF638R3487 by SignalP 2.0 HMM (Signal peptide probability 0.759) with cleavage site probability 0.366 between residues 17 and 18
862962014950	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962014951	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 9.9e-64
862962014952	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962014953	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
862962014954	HMMPfam hit to PF00467, KOW motif, score 0.00041
862962014955	VirE N-terminal domain; Region: VirE_N; pfam08800
862962014956	Virulence-associated protein E; Region: VirE; pfam05272
862962014957	HMMPfam hit to PF05272, Virulence-associated protein E, score 1.7e-20
862962014958	PS00017 ATP/GTP-binding site motif A (P-loop).
862962014959	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
862962014960	HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 1e-17
862962014961	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962014962	non-specific DNA binding site [nucleotide binding]; other site
862962014963	salt bridge; other site
862962014964	sequence-specific DNA binding site [nucleotide binding]; other site
862962014965	HMMPfam hit to PF01381, Helix-turn-helix, score 1.3e-13
862962014966	Domain of unknown function (DUF4248); Region: DUF4248; pfam14053
862962014967	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962014968	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
862962014969	tetramer (dimer of dimers) interface [polypeptide binding]; other site
862962014970	active site
862962014971	dimer interface [polypeptide binding]; other site
862962014972	HMMPfam hit to PF06026, Ribose 5-phosphate isomerase A (phosph, score 4e-55
862962014973	Protein of unknown function (DUF3843); Region: DUF3843; pfam12954
862962014974	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
862962014975	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962014976	Coenzyme A binding pocket [chemical binding]; other site
862962014977	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.6e-14
862962014978	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
862962014979	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962014980	non-specific DNA binding site [nucleotide binding]; other site
862962014981	salt bridge; other site
862962014982	sequence-specific DNA binding site [nucleotide binding]; other site
862962014983	HMMPfam hit to PF01381, Helix-turn-helix, score 3.4e-11
862962014984	Domain of unknown function (DUF955); Region: DUF955; cl01076
862962014985	HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 3.6e-12
862962014986	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962014987	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
862962014988	RuvA N terminal domain; Region: RuvA_N; pfam01330
862962014989	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
862962014990	HMMPfam hit to PF07499, RuvA, C-terminal domain, score 5.1e-12
862962014991	HMMPfam hit to PF01330, RuvA N terminal domain, score 2.4e-18
862962014992	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
862962014993	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
862962014994	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 1.2e-05
862962014995	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
862962014996	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
862962014997	HMMPfam hit to PF03006, Haemolysin-III related, score 1.5e-55
862962014998	7 probable transmembrane helices predicted for BF638R3506 by TMHMM2.0 at aa 12-33, 43-65, 85-102, 106-128, 135-157, 167-189 and 196-215
862962014999	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015000	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
862962015001	ATP cone domain; Region: ATP-cone; pfam03477
862962015002	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
862962015003	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
862962015004	HMMPfam hit to PF03477, ATP cone domain, score 6.6e-24
862962015005	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
862962015006	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
862962015007	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962015008	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962015009	putative substrate translocation pore; other site
862962015010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962015011	13 probable transmembrane helices predicted for BF638R3510 by TMHMM2.0 at aa 89-111, 126-148, 157-179, 184-203, 216-238, 243-265, 278-295, 305-322, 342-364, 379-401, 408-430, 474-496 and 503-525
862962015012	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.9e-64
862962015013	2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479
862962015014	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962015015	catalytic residue [active]
862962015016	HMMPfam hit to PF00266, Aminotransferase class-V, score 1.3e-06
862962015017	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
862962015018	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962015019	motif II; other site
862962015020	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 7e-13
862962015021	RIP metalloprotease RseP; Region: TIGR00054
862962015022	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
862962015023	active site
862962015024	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
862962015025	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
862962015026	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
862962015027	putative substrate binding region [chemical binding]; other site
862962015028	HMMPfam hit to PF02163, Peptidase family M50, score 2.7e-42
862962015029	3 probable transmembrane helices predicted for BF638R3514 by TMHMM2.0 at aa 107-129, 378-400 and 425-444
862962015030	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
862962015031	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
862962015032	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
862962015033	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
862962015034	HMMPfam hit to PF02670, 1-deoxy-D-xylulose 5-phosphate reduct, score 4.1e-193
862962015035	Signal peptide predicted for BF638R3515 by SignalP 2.0 HMM (Signal peptide probability 0.753) with cleavage site probability 0.416 between residues 24 and 25
862962015036	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
862962015037	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962015038	HMMPfam hit to PF01551, Peptidase family M23, score 7.3e-38
862962015039	1 probable transmembrane helix predicted for BF638R3516 by TMHMM2.0 at aa 41-63
862962015040	Signal peptide predicted for BF638R3516 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.811 between residues 56 and 57
862962015041	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
862962015042	RimM N-terminal domain; Region: RimM; pfam01782
862962015043	HMMPfam hit to PF05239, PRC-barrel domain, score 1.3e-05
862962015044	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
862962015045	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
862962015046	hinge; other site
862962015047	active site
862962015048	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 1.2e-49
862962015049	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015050	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
862962015051	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
862962015052	Glycoprotease family; Region: Peptidase_M22; pfam00814
862962015053	HMMPfam hit to PF00814, Glycoprotease family, score 3.1e-19
862962015054	Signal peptide predicted for BF638R3520 by SignalP 2.0 HMM (Signal peptide probability 0.793) with cleavage site probability 0.640 between residues 28 and 29
862962015055	hypothetical protein; Provisional; Region: PRK11820
862962015056	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
862962015057	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
862962015058	HMMPfam hit to PF03755, YicC-like family, N-terminal region, score 1.4e-26
862962015059	Guanylate kinase; Region: Guanylate_kin; pfam00625
862962015060	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
862962015061	catalytic site [active]
862962015062	G-X2-G-X-G-K; other site
862962015063	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015064	PS00856 Guanylate kinase signature.
862962015065	HMMPfam hit to PF00625, Guanylate kinase, score 2.7e-23
862962015066	PS00287 Cysteine proteases inhibitors signature.
862962015067	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
862962015068	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
862962015069	active site
862962015070	(T/H)XGH motif; other site
862962015071	HMMPfam hit to PF01467, Cytidylyltransferase, score 3.7e-31
862962015072	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
862962015073	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962015074	putative active site [active]
862962015075	putative metal binding site [ion binding]; other site
862962015076	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.7e-13
862962015077	Signal peptide predicted for BF638R3526 by SignalP 2.0 HMM (Signal peptide probability 0.844) with cleavage site probability 0.292 between residues 33 and 34
862962015078	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015079	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
862962015080	UbiA prenyltransferase family; Region: UbiA; pfam01040
862962015081	Signal peptide predicted for BF638R3527 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.924 between residues 34 and 35
862962015082	7 probable transmembrane helices predicted for BF638R3527 by TMHMM2.0 at aa 12-34, 38-60, 95-114, 118-140, 147-169, 174-193 and 214-236
862962015083	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015084	HMMPfam hit to PF01040, UbiA prenyltransferase family, score 1.9e-13
862962015085	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015086	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
862962015087	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
862962015088	NAD binding site [chemical binding]; other site
862962015089	substrate binding site [chemical binding]; other site
862962015090	homodimer interface [polypeptide binding]; other site
862962015091	active site
862962015092	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 9.2e-137
862962015093	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
862962015094	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
862962015095	substrate binding site; other site
862962015096	tetramer interface; other site
862962015097	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.2e-104
862962015098	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
862962015099	active site
862962015100	metal binding site [ion binding]; metal-binding site
862962015101	homotetramer interface [polypeptide binding]; other site
862962015102	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2.7e-05
862962015103	polyphosphate kinase; Provisional; Region: PRK05443
862962015104	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
862962015105	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
862962015106	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
862962015107	domain interface [polypeptide binding]; other site
862962015108	active site
862962015109	catalytic site [active]
862962015110	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
862962015111	domain interface [polypeptide binding]; other site
862962015112	active site
862962015113	catalytic site [active]
862962015114	HMMPfam hit to PF02503, Polyphosphate kinase, score 2.3e-195
862962015115	Phosphate transporter family; Region: PHO4; cl00396
862962015116	11 probable transmembrane helices predicted for BF638R3532 by TMHMM2.0 at aa 24-46, 61-83, 96-118, 169-191, 203-225, 245-267, 274-296, 332-349, 432-454, 474-496 and 503-525
862962015117	Response regulator receiver domain; Region: Response_reg; pfam00072
862962015118	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962015119	active site
862962015120	phosphorylation site [posttranslational modification]
862962015121	intermolecular recognition site; other site
862962015122	dimerization interface [polypeptide binding]; other site
862962015123	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-24
862962015124	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
862962015125	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962015126	Walker A/P-loop; other site
862962015127	ATP binding site [chemical binding]; other site
862962015128	Q-loop/lid; other site
862962015129	ABC transporter signature motif; other site
862962015130	Walker B; other site
862962015131	D-loop; other site
862962015132	H-loop/switch region; other site
862962015133	ABC transporter; Region: ABC_tran_2; pfam12848
862962015134	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962015135	HMMPfam hit to PF00005, ABC transporter, score 1.2e-44
862962015136	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015137	PS00211 ABC transporters family signature.
862962015138	HMMPfam hit to PF00005, ABC transporter, score 7.5e-33
862962015139	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015140	PS00211 ABC transporters family signature.
862962015141	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
862962015142	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962015143	Signal peptide predicted for BF638R3537 by SignalP 2.0 HMM (Signal peptide probability 0.976) with cleavage site probability 0.584 between residues 20 and 21
862962015144	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015145	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962015146	Protein export membrane protein; Region: SecD_SecF; cl14618
862962015147	Signal peptide predicted for BF638R3538 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.442 between residues 32 and 33
862962015148	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962015149	10 probable transmembrane helices predicted for BF638R3538 by TMHMM2.0 at aa 13-32, 363-385, 444-466, 476-498, 536-555, 861-883, 890-912, 916-938, 968-990 and 1000-1022
862962015150	Outer membrane efflux protein; Region: OEP; pfam02321
862962015151	Outer membrane efflux protein; Region: OEP; pfam02321
862962015152	Signal peptide predicted for BF638R3539 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.800 between residues 19 and 20
862962015153	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.01
862962015154	HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.3e-05
862962015155	Glycosyl hydrolase family 43; Region: GH43_5; cd08984
862962015156	active site
862962015157	Signal peptide predicted for BF638R3540 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.984 between residues 19 and 20
862962015158	1 probable transmembrane helix predicted for BF638R3541 by TMHMM2.0 at aa 21-40
862962015159	Signal peptide predicted for BF638R3541 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.984 between residues 36 and 37
862962015160	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
862962015161	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962015162	S-adenosylmethionine binding site [chemical binding]; other site
862962015163	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
862962015164	HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 2.6e-18
862962015165	Signal peptide predicted for BF638R3544 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 20 and 21
862962015166	4 probable transmembrane helices predicted for BF638R3544 by TMHMM2.0 at aa 5-27, 80-102, 141-158 and 162-181
862962015167	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962015168	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962015169	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962015170	DNA binding residues [nucleotide binding]
862962015171	HMMPfam hit to PF04542, Sigma-70 region, score 6.4e-19
862962015172	PS01063 Sigma-70 factors ECF subfamily signature.
862962015173	HMMPfam hit to PF04545, Sigma-70, region, score 2.8e-10
862962015174	2 probable transmembrane helices predicted for BF638R3546 by TMHMM2.0 at aa 40-62 and 90-107
862962015175	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
862962015176	PLD-like domain; Region: PLDc_2; pfam13091
862962015177	putative active site [active]
862962015178	catalytic site [active]
862962015179	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
862962015180	PLD-like domain; Region: PLDc_2; pfam13091
862962015181	putative active site [active]
862962015182	catalytic site [active]
862962015183	Signal peptide predicted for BF638R3547 by SignalP 2.0 HMM (Signal peptide probability 0.910) with cleavage site probability 0.794 between residues 19 and 20
862962015184	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.00079
862962015185	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 2.7e-08
862962015186	thymidylate synthase; Reviewed; Region: thyA; PRK01827
862962015187	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
862962015188	dimerization interface [polypeptide binding]; other site
862962015189	active site
862962015190	HMMPfam hit to PF00303, Thymidylate synthase, score 2.6e-177
862962015191	PS00091 Thymidylate synthase active site.
862962015192	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
862962015193	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
862962015194	folate binding site [chemical binding]; other site
862962015195	NADP+ binding site [chemical binding]; other site
862962015196	HMMPfam hit to PF00186, Dihydrofolate reductase, score 2.1e-49
862962015197	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
862962015198	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
862962015199	putative DNA binding site [nucleotide binding]; other site
862962015200	putative Zn2+ binding site [ion binding]; other site
862962015201	AsnC family; Region: AsnC_trans_reg; pfam01037
862962015202	HMMPfam hit to PF01037, AsnC family, score 4.6e-22
862962015203	IgA Peptidase M64; Region: Peptidase_M64; pfam09471
862962015204	Signal peptide predicted for BF638R3551 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 19 and 20
862962015205	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015206	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962015207	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
862962015208	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
862962015209	1 probable transmembrane helix predicted for BF638R3552 by TMHMM2.0 at aa 20-42
862962015210	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
862962015211	1 probable transmembrane helix predicted for BF638R3553 by TMHMM2.0 at aa 15-32
862962015212	4 probable transmembrane helices predicted for BF638R3554 by TMHMM2.0 at aa 7-29, 49-71, 83-105 and 129-151
862962015213	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
862962015214	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 3.6e-11
862962015215	4 probable transmembrane helices predicted for BF638R3555 by TMHMM2.0 at aa 5-24, 78-100, 176-198 and 213-235
862962015216	Signal peptide predicted for BF638R3555 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.984 between residues 24 and 25
862962015217	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
862962015218	active site
862962015219	HMMPfam hit to PF01026, TatD related DNase, score 9.6e-82
862962015220	PS01090 Uncharacterized protein family UPF0006 signature 2.
862962015221	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
862962015222	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
862962015223	substrate binding pocket [chemical binding]; other site
862962015224	chain length determination region; other site
862962015225	substrate-Mg2+ binding site; other site
862962015226	catalytic residues [active]
862962015227	aspartate-rich region 1; other site
862962015228	active site lid residues [active]
862962015229	aspartate-rich region 2; other site
862962015230	HMMPfam hit to PF00348, Polyprenyl synthetase, score 4e-77
862962015231	PS00444 Polyprenyl synthetases signature 2.
862962015232	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015233	PS00723 Polyprenyl synthetases signature 1.
862962015234	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
862962015235	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
862962015236	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 2.8e-07
862962015237	1 probable transmembrane helix predicted for BF638R3560 by TMHMM2.0 at aa 20-37
862962015238	cytidylate kinase; Provisional; Region: cmk; PRK00023
862962015239	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
862962015240	CMP-binding site; other site
862962015241	The sites determining sugar specificity; other site
862962015242	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015243	HMMPfam hit to PF02224, Cytidylate kinase, score 5.5e-63
862962015244	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
862962015245	LytB protein; Region: LYTB; cl00507
862962015246	HMMPfam hit to PF02401, LytB protein, score 2.3e-48
862962015247	6-phosphofructokinase; Provisional; Region: PRK03202
862962015248	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
862962015249	active site
862962015250	ADP/pyrophosphate binding site [chemical binding]; other site
862962015251	dimerization interface [polypeptide binding]; other site
862962015252	allosteric effector site; other site
862962015253	fructose-1,6-bisphosphate binding site; other site
862962015254	HMMPfam hit to PF00365, Phosphofructokinase, score 4.7e-156
862962015255	PS00433 Phosphofructokinase signature.
862962015256	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
862962015257	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
862962015258	putative NAD(P) binding site [chemical binding]; other site
862962015259	active site
862962015260	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-24
862962015261	PS00061 Short-chain dehydrogenases/reductases family signature.
862962015262	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
862962015263	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
862962015264	active site
862962015265	FMN binding site [chemical binding]; other site
862962015266	substrate binding site [chemical binding]; other site
862962015267	putative catalytic residue [active]
862962015268	HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 3.3e-38
862962015269	3-oxo-5-alpha-steroid 4-dehydrogenase; Region: Steroid_dh; cl17474
862962015270	HMMPfam hit to PF02544, 3-oxo-5-alpha-steroid 4-dehydrogenase, score 2.9e-39
862962015271	6 probable transmembrane helices predicted for BF638R3566 by TMHMM2.0 at aa 13-35, 55-74, 79-101, 114-136, 146-168 and 205-227
862962015272	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015273	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1_2; cd06113
862962015274	dimer interface [polypeptide binding]; other site
862962015275	Citrate synthase; Region: Citrate_synt; pfam00285
862962015276	active site
862962015277	citrylCoA binding site [chemical binding]; other site
862962015278	oxalacetate/citrate binding site [chemical binding]; other site
862962015279	coenzyme A binding site [chemical binding]; other site
862962015280	catalytic triad [active]
862962015281	HMMPfam hit to PF00285, Citrate synthase, score 5.6e-73
862962015282	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
862962015283	isocitrate dehydrogenase; Validated; Region: PRK06451
862962015284	HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 6.7e-136
862962015285	PS00470 Isocitrate and isopropylmalate dehydrogenases signature.
862962015286	aconitate hydratase, mitochondrial; Region: aconitase_mito; TIGR01340
862962015287	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
862962015288	substrate binding site [chemical binding]; other site
862962015289	ligand binding site [chemical binding]; other site
862962015290	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
862962015291	substrate binding site [chemical binding]; other site
862962015292	HMMPfam hit to PF00694, Aconitase C-terminal domain, score 2.1e-52
862962015293	HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 4e-201
862962015294	PS01244 Aconitase family signature 2.
862962015295	PS00450 Aconitase family signature 1.
862962015296	AAA domain; Region: AAA_11; pfam13086
862962015297	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962015298	ATP binding site [chemical binding]; other site
862962015299	AAA domain; Region: AAA_30; pfam13604
862962015300	AAA domain; Region: AAA_12; pfam13087
862962015301	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015302	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
862962015303	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015304	1 probable transmembrane helix predicted for BF638R3571 by TMHMM2.0 at aa 17-39
862962015305	Signal peptide predicted for BF638R3571 by SignalP 2.0 HMM (Signal peptide probability 0.674) with cleavage site probability 0.575 between residues 36 and 37
862962015306	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
862962015307	ketol-acid reductoisomerase; Region: ilvC; TIGR00465
862962015308	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
862962015309	HMMPfam hit to PF01450, Acetohydroxy acid isomeroreductase, catalyti, score 1.6e-50
862962015310	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962015311	1 probable transmembrane helix predicted for BF638R3574 by TMHMM2.0 at aa 7-26
862962015312	Signal peptide predicted for BF638R3574 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.582 between residues 20 and 21
862962015313	Signal peptide predicted for BF638R3573 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.572 between residues 17 and 18
862962015314	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
862962015315	active site
862962015316	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
862962015317	active site 2 [active]
862962015318	HMMPfam hit to PF01643, Acyl-ACP thioesterase, score 1e-22
862962015319	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
862962015320	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
862962015321	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
862962015322	HMMPfam hit to PF01842, ACT domain, score 3.3e-11
862962015323	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
862962015324	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
862962015325	PYR/PP interface [polypeptide binding]; other site
862962015326	dimer interface [polypeptide binding]; other site
862962015327	TPP binding site [chemical binding]; other site
862962015328	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
862962015329	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
862962015330	TPP-binding site [chemical binding]; other site
862962015331	dimer interface [polypeptide binding]; other site
862962015332	HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 2.6e-49
862962015333	HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 1.9e-91
862962015334	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
862962015335	HMMPfam hit to PF00920, Dehydratase family, score 0
862962015336	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
862962015337	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
862962015338	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
862962015339	Signal peptide predicted for BF638R3579 by SignalP 2.0 HMM (Signal peptide probability 0.876) with cleavage site probability 0.341 between residues 24 and 25
862962015340	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015341	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; pfam09603
862962015342	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.3e-10
862962015343	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015344	Signal peptide predicted for BF638R3580 by SignalP 2.0 HMM (Signal peptide probability 0.870) with cleavage site probability 0.329 between residues 41 and 42
862962015345	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; pfam09603
862962015346	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 9.7e-11
862962015347	Signal peptide predicted for BF638R3581 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.801 between residues 22 and 23
862962015348	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015349	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; pfam09603
862962015350	PS00018 EF-hand calcium-binding domain.
862962015351	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.1e-10
862962015352	Signal peptide predicted for BF638R3582 by SignalP 2.0 HMM (Signal peptide probability 0.860) with cleavage site probability 0.754 between residues 21 and 22
862962015353	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
862962015354	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962015355	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962015356	ligand binding site [chemical binding]; other site
862962015357	HMMPfam hit to PF00691, OmpA family, score 8.4e-10
862962015358	Signal peptide predicted for BF638R3583 by SignalP 2.0 HMM (Signal peptide probability 0.951) with cleavage site probability 0.702 between residues 33 and 34
862962015359	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962015360	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962015361	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.052
862962015362	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.0017
862962015363	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
862962015364	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
862962015365	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 0.00045
862962015366	Signal peptide predicted for BF638R3586 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.938 between residues 21 and 22
862962015367	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015368	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
862962015369	HMMPfam hit to PF06354, Protein of unknown function (DUF1063), score 3.9e-188
862962015370	PS00022 EGF-like domain signature 1.
862962015371	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015372	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015373	1 probable transmembrane helix predicted for BF638R3587 by TMHMM2.0 at aa 83-105
862962015374	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
862962015375	active site
862962015376	Signal peptide predicted for BF638R3588 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 23 and 24
862962015377	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
862962015378	Signal peptide predicted for BF638R3589 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.666 between residues 21 and 22
862962015379	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015380	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962015381	Signal peptide predicted for BF638R3590 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 21 and 22
862962015382	Signal peptide predicted for BF638R3591 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.914 between residues 21 and 22
862962015383	Signal peptide predicted for BF638R3592 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.621 between residues 22 and 23
862962015384	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015385	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962015386	putative catalytic site [active]
862962015387	putative metal binding site [ion binding]; other site
862962015388	putative phosphate binding site [ion binding]; other site
862962015389	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.4e-08
862962015390	Signal peptide predicted for BF638R3593 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.718 between residues 24 and 25
862962015391	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015392	Uncharacterized conserved protein [Function unknown]; Region: COG3379
862962015393	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
862962015394	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015395	1 probable transmembrane helix predicted for BF638R3594 by TMHMM2.0 at aa 7-24
862962015396	Signal peptide predicted for BF638R3594 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.942 between residues 23 and 24
862962015397	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962015398	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
862962015399	active site
862962015400	metal binding site [ion binding]; metal-binding site
862962015401	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
862962015402	active site
862962015403	PQQ-like domain; Region: PQQ_2; pfam13360
862962015404	Trp docking motif [polypeptide binding]; other site
862962015405	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.1e-08
862962015406	Signal peptide predicted for BF638R3595 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 21 and 22
862962015407	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962015408	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962015409	SusD family; Region: SusD; pfam07980
862962015410	Signal peptide predicted for BF638R3596 by SignalP 2.0 HMM (Signal peptide probability 0.622) with cleavage site probability 0.152 between residues 49 and 50
862962015411	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015412	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962015413	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962015414	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962015415	HMMPfam hit to PF00593, TonB dependent receptor, score 1.6e-16
862962015416	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.9e-20
862962015417	Signal peptide predicted for BF638R3597 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 39 and 40
862962015418	1 probable transmembrane helix predicted for BF638R3597 by TMHMM2.0 at aa 21-39
862962015419	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962015420	FecR protein; Region: FecR; pfam04773
862962015421	HMMPfam hit to PF04773, FecR protein, score 1.2e-28
862962015422	1 probable transmembrane helix predicted for BF638R3598 by TMHMM2.0 at aa 92-114
862962015423	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962015424	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962015425	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962015426	DNA binding residues [nucleotide binding]
862962015427	HMMPfam hit to PF04542, Sigma-70 region, score 2.7e-09
862962015428	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962015429	SusD family; Region: SusD; pfam07980
862962015430	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015431	Signal peptide predicted for BF638R3600 by SignalP 2.0 HMM (Signal peptide probability 0.895) with cleavage site probability 0.452 between residues 22 and 23
862962015432	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962015433	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962015434	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962015435	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962015436	HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-16
862962015437	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9e-19
862962015439	HMMPfam hit to PF00754, F5/8 type C domain, score 4.1e-28
862962015440	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962015441	SusD family; Region: SusD; pfam07980
862962015442	1 probable transmembrane helix predicted for BF638R3603 by TMHMM2.0 at aa 7-26
862962015443	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015444	Signal peptide predicted for BF638R3603 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.541 between residues 20 and 21
862962015445	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962015446	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962015447	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962015448	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962015449	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962015450	HMMPfam hit to PF00593, TonB dependent receptor, score 2.8e-15
862962015451	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.4e-16
862962015452	Signal peptide predicted for BF638R3604 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.766 between residues 51 and 52
862962015453	1 probable transmembrane helix predicted for BF638R3604 by TMHMM2.0 at aa 25-47
862962015454	FecR protein; Region: FecR; pfam04773
862962015455	HMMPfam hit to PF04773, FecR protein, score 4.6e-21
862962015456	1 probable transmembrane helix predicted for BF638R3605 by TMHMM2.0 at aa 103-125
862962015457	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
862962015458	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962015459	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962015460	DNA binding residues [nucleotide binding]
862962015461	HMMPfam hit to PF04542, Sigma-70 region, score 0.00099
862962015462	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
862962015463	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
862962015464	Tetramer interface [polypeptide binding]; other site
862962015465	active site
862962015466	FMN-binding site [chemical binding]; other site
862962015467	HMMPfam hit to PF01264, Chorismate synthase, score 8.4e-187
862962015468	PS00787 Chorismate synthase signature 1.
862962015469	PS00788 Chorismate synthase signature 2.
862962015470	PS00789 Chorismate synthase signature 3.
862962015471	hypothetical protein; Provisional; Region: PRK08201
862962015472	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
862962015473	metal binding site [ion binding]; metal-binding site
862962015474	putative dimer interface [polypeptide binding]; other site
862962015475	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.9e-29
862962015476	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 3.7e-27
862962015477	Choloylglycine hydrolase (CGH) is a bile salt-modifying enzyme that hydrolyzes non-peptide carbon-nitrogen bonds in choloylglycine and choloyltaurine, both of which are present in bile.  CGH is present in a number of probiotic microbial organisms that...; Region: Ntn_CGH; cd01902
862962015478	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
862962015479	HMMPfam hit to PF02275, Linear amide C-N hydrolases, choloylglycine, score 5.8e-42
862962015480	Signal peptide predicted for BF638R3610 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.734 between residues 26 and 27
862962015481	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
862962015482	catalytic residues [active]
862962015483	PS00070 Aldehyde dehydrogenases cysteine active site.
862962015484	PS00687 Aldehyde dehydrogenases glutamic acid active site.
862962015485	Domain of unknown function (DUF4396); Region: DUF4396; pfam14342
862962015486	6 probable transmembrane helices predicted for BF638R3612 by TMHMM2.0 at aa 7-29, 39-61, 100-122, 132-154, 175-197 and 210-232
862962015487	Signal peptide predicted for BF638R3612 by SignalP 2.0 HMM (Signal peptide probability 0.907) with cleavage site probability 0.631 between residues 25 and 26
862962015488	DNA topoisomerase III; Provisional; Region: PRK07726
862962015489	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
862962015490	active site
862962015491	putative interdomain interaction site [polypeptide binding]; other site
862962015492	putative metal-binding site [ion binding]; other site
862962015493	putative nucleotide binding site [chemical binding]; other site
862962015494	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962015495	domain I; other site
862962015496	DNA binding groove [nucleotide binding]
862962015497	phosphate binding site [ion binding]; other site
862962015498	domain II; other site
862962015499	domain III; other site
862962015500	nucleotide binding site [chemical binding]; other site
862962015501	catalytic site [active]
862962015502	domain IV; other site
862962015503	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015504	HMMPfam hit to PF01131, DNA topoisomerase, score 6.7e-100
862962015505	HMMPfam hit to PF01751, Toprim domain, score 5.1e-21
862962015506	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
862962015507	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
862962015508	Signal peptide predicted for BF638R3614 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.578 between residues 28 and 29
862962015509	1 probable transmembrane helix predicted for BF638R3614 by TMHMM2.0 at aa 17-36
862962015510	HMMPfam hit to PF01120, Alpha-L-fucosidase, score 4.2e-14
862962015511	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
862962015512	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
862962015513	active site
862962015514	substrate binding site [chemical binding]; other site
862962015515	coenzyme B12 binding site [chemical binding]; other site
862962015516	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
862962015517	B12 binding site [chemical binding]; other site
862962015518	cobalt ligand [ion binding]; other site
862962015519	HMMPfam hit to PF02310, B12 binding domain, score 1.1e-27
862962015520	HMMPfam hit to PF01642, Methylmalonyl-CoA mutase, score 0
862962015521	PS00544 Methylmalonyl-CoA mutase signature.
862962015522	methylmalonyl-CoA mutase, heterodimeric type, beta chain; Region: mmCoA_mut_beta; TIGR00642
862962015523	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
862962015524	heterodimer interface [polypeptide binding]; other site
862962015525	substrate interaction site [chemical binding]; other site
862962015526	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
862962015527	HMMPfam hit to PF01642, Methylmalonyl-CoA mutase, score 1.5e-149
862962015528	PS00118 Phospholipase A2 histidine active site.
862962015529	putative transporter; Validated; Region: PRK03818
862962015530	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
862962015531	TrkA-C domain; Region: TrkA_C; pfam02080
862962015532	TrkA-C domain; Region: TrkA_C; pfam02080
862962015533	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
862962015534	9 probable transmembrane helices predicted for BF638R3617 by TMHMM2.0 at aa 13-31, 36-58, 73-92, 99-121, 161-183, 376-395, 405-422, 442-464 and 468-490
862962015535	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 6.5e-63
862962015536	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015537	HMMPfam hit to PF02080, TrkA-C domain, score 1.3e-09
862962015538	HMMPfam hit to PF02080, TrkA-C domain, score 1.2e-14
862962015539	HMMPfam hit to PF06826, Predicted Permease Membrane Region, score 7.7e-64
862962015540	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
862962015541	1 probable transmembrane helix predicted for BF638R3618 by TMHMM2.0 at aa 5-27
862962015542	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962015543	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
862962015544	12 probable transmembrane helices predicted for BF638R3619 by TMHMM2.0 at aa 41-63, 78-100, 120-142, 157-179, 191-213, 217-239, 263-285, 298-320, 350-372, 387-406, 419-441 and 445-464
862962015545	HMMPfam hit to PF01554, MatE, score 1.4e-20
862962015546	HMMPfam hit to PF01554, MatE, score 1.2e-20
862962015547	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
862962015548	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
862962015549	ligand binding site [chemical binding]; other site
862962015550	flexible hinge region; other site
862962015551	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 0.002
862962015552	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962015553	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
862962015554	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
862962015555	active site
862962015556	nucleophile elbow; other site
862962015557	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962015558	HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.4e-37
862962015559	1 probable transmembrane helix predicted for BF638R3622 by TMHMM2.0 at aa 5-24
862962015560	Signal peptide predicted for BF638R3622 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 23 and 24
862962015561	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
862962015562	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
862962015563	11 probable transmembrane helices predicted for BF638R3623 by TMHMM2.0 at aa 32-54, 69-91, 111-133, 153-175, 196-218, 254-276, 283-305, 331-353, 374-396, 401-421 and 428-450
862962015564	HMMPfam hit to PF01554, MatE, score 1.5e-20
862962015565	HMMPfam hit to PF01554, MatE, score 1.3e-33
862962015566	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
862962015567	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
862962015568	dimer interface [polypeptide binding]; other site
862962015569	putative anticodon binding site; other site
862962015570	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
862962015571	motif 1; other site
862962015572	active site
862962015573	motif 2; other site
862962015574	motif 3; other site
862962015575	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
862962015576	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.4e-18
862962015577	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 5.2e-163
862962015578	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962015579	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962015580	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
862962015581	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
862962015582	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
862962015583	Signal peptide predicted for BF638R3625 by SignalP 2.0 HMM (Signal peptide probability 0.890) with cleavage site probability 0.879 between residues 25 and 26
862962015584	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 4.3e-29
862962015585	HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate deh, score 7e-42
862962015586	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
862962015587	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
862962015588	active site
862962015589	dimer interface [polypeptide binding]; other site
862962015590	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
862962015591	dimer interface [polypeptide binding]; other site
862962015592	active site
862962015593	HMMPfam hit to PF00342, Phosphoglucose isomerase, score 2.6e-110
862962015594	PS00765 Phosphoglucose isomerase signature 1.
862962015595	PS00174 Phosphoglucose isomerase signature 2.
862962015596	Signal peptide predicted for BF638R3627 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.436 between residues 19 and 20
862962015597	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015598	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
862962015599	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962015600	motif II; other site
862962015601	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.6e-23
862962015602	Prophage
862962015603	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962015604	active site
862962015605	Int/Topo IB signature motif; other site
862962015606	DNA binding site [nucleotide binding]
862962015607	HMMPfam hit to PF00589, Phage integrase family, score 5e-06
862962015608	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
862962015609	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
862962015610	SLBB domain; Region: SLBB; pfam10531
862962015611	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
862962015612	SLBB domain; Region: SLBB; pfam10531
862962015613	SLBB domain; Region: SLBB; pfam10531
862962015614	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
862962015615	SLBB domain; Region: SLBB; pfam10531
862962015616	HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 7.6e-13
862962015617	2 probable transmembrane helices predicted for BF638R3630 by TMHMM2.0 at aa 5-24 and 36-53
862962015618	Signal peptide predicted for BF638R3630 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.915 between residues 50 and 51
862962015619	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
862962015620	amidase catalytic site [active]
862962015621	Zn binding residues [ion binding]; other site
862962015622	substrate binding site [chemical binding]; other site
862962015623	HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 6e-09
862962015624	PS00018 EF-hand calcium-binding domain.
862962015625	Holin family; Region: Phage_holin_4; cl01989
862962015626	3 probable transmembrane helices predicted for BF638R3633 by TMHMM2.0 at aa 7-26, 31-48 and 68-90
862962015627	PS00496 P-II protein urydylation site.
862962015628	tape measure domain; Region: tape_meas_nterm; TIGR02675
862962015629	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015630	Phage major tail protein 2; Region: Phage_tail_2; cl11463
862962015631	Phage head-tail joining protein; Region: Phage_H_T_join; cl11461
862962015632	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
862962015633	oligomerization interface [polypeptide binding]; other site
862962015634	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
862962015635	Phage capsid family; Region: Phage_capsid; pfam05065
862962015636	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
862962015637	HMMPfam hit to PF04586, Caudovirus prohead protease, score 7.8e-33
862962015638	Phage-related protein [Function unknown]; Region: COG4695
862962015639	Phage portal protein; Region: Phage_portal; pfam04860
862962015640	HMMPfam hit to PF04860, Phage portal protein, score 1.3e-60
862962015641	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
862962015642	HMMPfam hit to PF03354, Phage Terminase, score 3.5e-105
862962015643	Phage terminase, small subunit; Region: Terminase_4; pfam05119
862962015644	HMMPfam hit to PF05119, Phage terminase, small subunit, score 4.3e-08
862962015645	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
862962015646	active site
862962015647	HMMPfam hit to PF01844, HNH endonuclease, score 2.8e-08
862962015648	PS00190 Cytochrome c family heme-binding site signature.
862962015649	hypothetical protein; Provisional; Region: PRK05968
862962015650	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
862962015651	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962015652	PcfJ-like protein; Region: PcfJ; pfam14284
862962015653	PcfK-like protein; Region: PcfK; pfam14058
862962015654	DNA methylase; Region: N6_N4_Mtase; pfam01555
862962015655	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
862962015656	HMMPfam hit to PF01555, DNA methylase, score 6.1e-17
862962015657	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
862962015658	PS00028 Zinc finger, C2H2 type, domain.
862962015659	PS00190 Cytochrome c family heme-binding site signature.
862962015660	1 probable transmembrane helix predicted for BF638R3670 by TMHMM2.0 at aa 7-29
862962015661	Signal peptide predicted for BF638R3670 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.734 between residues 27 and 28
862962015662	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015663	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962015664	1 probable transmembrane helix predicted for BF638R3672 by TMHMM2.0 at aa 5-24
862962015665	Signal peptide predicted for BF638R3672 by SignalP 2.0 HMM (Signal peptide probability 0.856) with cleavage site probability 0.446 between residues 22 and 23
862962015666	Spi protease inhibitor; Region: Inhibitor_I69; pfam13734
862962015667	Peptidase C10 family; Region: Peptidase_C10; pfam01640
862962015668	Signal peptide predicted for BF638R3679 by SignalP 2.0 HMM (Signal peptide probability 0.621) with cleavage site probability 0.531 between residues 23 and 24
862962015669	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015670	Signal peptide predicted for BF638R3680 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.278 between residues 21 and 22
862962015671	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015672	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
862962015673	dimer interface [polypeptide binding]; other site
862962015674	active site
862962015675	HMMPfam hit to PF03590, Aspartate-ammonia ligase, score 8.9e-121
862962015676	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015677	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
862962015678	ligand binding site [chemical binding]; other site
862962015679	active site
862962015680	UGI interface [polypeptide binding]; other site
862962015681	catalytic site [active]
862962015682	HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 4e-77
862962015683	PS00130 Uracil-DNA glycosylase signature.
862962015684	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
862962015685	1 probable transmembrane helix predicted for BF638R3683 by TMHMM2.0 at aa 7-26
862962015686	Signal peptide predicted for BF638R3683 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.504 between residues 25 and 26
862962015687	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962015688	Zn2+ binding site [ion binding]; other site
862962015689	Mg2+ binding site [ion binding]; other site
862962015690	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962015691	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962015692	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962015693	active site
862962015694	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
862962015695	PA14 domain; Region: PA14; pfam07691
862962015696	Signal peptide predicted for BF638R3685 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.507 between residues 31 and 32
862962015697	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015698	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.032
862962015699	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 1.5e-156
862962015700	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015701	HMMPfam hit to PF07691, PA14 domain, score 2.9e-23
862962015702	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962015703	Coenzyme A binding pocket [chemical binding]; other site
862962015704	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.7e-11
862962015705	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
862962015706	8 probable transmembrane helices predicted for BF638R3687 by TMHMM2.0 at aa 19-41, 56-78, 85-102, 112-134, 146-168, 183-205, 212-231 and 257-279
862962015707	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015708	Signal peptide predicted for BF638R3687 by SignalP 2.0 HMM (Signal peptide probability 0.733) with cleavage site probability 0.246 between residues 28 and 29
862962015709	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
862962015710	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
862962015711	active site
862962015712	metal binding site [ion binding]; metal-binding site
862962015713	Signal peptide predicted for BF638R3688 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.921 between residues 29 and 30
862962015714	1 probable transmembrane helix predicted for BF638R3688 by TMHMM2.0 at aa 7-29
862962015715	HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 5.6e-30
862962015716	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
862962015717	mce related protein; Region: MCE; pfam02470
862962015718	Signal peptide predicted for BF638R3689 by SignalP 2.0 HMM (Signal peptide probability 0.821) with cleavage site probability 0.500 between residues 24 and 25
862962015719	HMMPfam hit to PF02470, mce related protein, score 0.00014
862962015720	1 probable transmembrane helix predicted for BF638R3689 by TMHMM2.0 at aa 12-34
862962015721	DnaA N-terminal domain; Region: DnaA_N; pfam11638
862962015722	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
862962015723	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962015724	Walker A motif; other site
862962015725	ATP binding site [chemical binding]; other site
862962015726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
862962015727	Walker B motif; other site
862962015728	arginine finger; other site
862962015729	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
862962015730	DnaA box-binding interface [nucleotide binding]; other site
862962015731	HMMPfam hit to PF00308, Bacterial dnaA protein, score 1.6e-131
862962015732	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015733	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
862962015734	dimer interface [polypeptide binding]; other site
862962015735	FMN binding site [chemical binding]; other site
862962015736	NADPH bind site [chemical binding]; other site
862962015737	HMMPfam hit to PF00881, Nitroreductase family, score 2.1e-22
862962015738	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
862962015739	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
862962015740	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
862962015741	active site
862962015742	dimer interface [polypeptide binding]; other site
862962015743	effector binding site; other site
862962015744	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
862962015745	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 1.4e-12
862962015746	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cd05467
862962015747	4-alpha-glucanotransferase; Region: PLN02950
862962015748	starch-binding site 2 [chemical binding]; other site
862962015749	starch-binding site 1 [chemical binding]; other site
862962015750	Disproportionating enzyme 2 (DPE2), N-terminal CBM20 (carbohydrate-binding module, family 20) domain, repeat 2. DPE2 is a transglucosidase that is essential for the cytosolic metabolism of maltose in plant leaves at night. Maltose is an intermediate on...; Region: CBM20_DPE2_repeat2; cd05816
862962015751	starch binding site 2 [chemical binding]; other site
862962015752	starch binding site 1 [chemical binding]; other site
862962015753	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
862962015754	HMMPfam hit to PF00686, Starch binding domain, score 1e-05
862962015755	HMMPfam hit to PF02446, 4-alpha-glucanotransferase, score 1.5e-124
862962015756	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
862962015757	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962015758	Signal peptide predicted for BF638R3694 by SignalP 2.0 HMM (Signal peptide probability 0.723) with cleavage site probability 0.273 between residues 17 and 18
862962015759	11 probable transmembrane helices predicted for BF638R3694 by TMHMM2.0 at aa 4-21, 34-56, 71-93, 100-122, 150-167, 174-191, 201-223, 236-253, 263-280, 287-308 and 323-345
862962015760	HMMPfam hit to PF01757, Acyltransferase family, score 4.1e-06
862962015761	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
862962015762	active site
862962015763	HMMPfam hit to PF02152, Dihydroneopterin aldolase, score 5.4e-18
862962015764	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962015765	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962015766	catalytic residues [active]
862962015767	Signal peptide predicted for BF638R3696 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.759 between residues 21 and 22
862962015768	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
862962015769	active site
862962015770	dimer interfaces [polypeptide binding]; other site
862962015771	catalytic residues [active]
862962015772	HMMPfam hit to PF02142, MGS-like domain, score 2.3e-05
862962015773	PS01335 Methylglyoxal synthase active site.
862962015774	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
862962015775	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
862962015776	Probable Catalytic site; other site
862962015777	metal-binding site
862962015778	HMMPfam hit to PF00535, Glycosyl transferase, score 4.5e-22
862962015779	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
862962015780	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
862962015781	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
862962015782	putative acyl-acceptor binding pocket; other site
862962015783	HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltr, score 2.2e-11
862962015784	Signal peptide predicted for BF638R3699 by SignalP 2.0 HMM (Signal peptide probability 0.790) with cleavage site probability 0.578 between residues 27 and 28
862962015785	1 probable transmembrane helix predicted for BF638R3699 by TMHMM2.0 at aa 5-27
862962015786	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
862962015787	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
862962015788	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962015789	FeS/SAM binding site; other site
862962015790	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.3e-25
862962015791	PS01278 Uncharacterized protein family UPF0004 signature.
862962015792	HMMPfam hit to PF00919, Uncharacterized protein family UPF0004, score 4e-26
862962015793	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015794	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
862962015795	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962015796	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
862962015797	putative AMP binding site [chemical binding]; other site
862962015798	putative active site [active]
862962015799	acyl-activating enzyme (AAE) consensus motif; other site
862962015800	putative CoA binding site [chemical binding]; other site
862962015801	HMMPfam hit to PF00501, AMP-binding enzyme, score 1.7e-87
862962015802	PS00455 Putative AMP-binding domain signature.
862962015803	Signal peptide predicted for BF638R3702 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.486 between residues 24 and 25
862962015804	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015805	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
862962015806	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
862962015807	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
862962015808	HMMPfam hit to PF03948, Ribosomal protein L9, C-terminal domai, score 1.7e-15
862962015809	HMMPfam hit to PF01281, Ribosomal protein L9, N-terminal domai, score 1.9e-19
862962015810	PS00651 Ribosomal protein L9 signature.
862962015811	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
862962015812	HMMPfam hit to PF01084, Ribosomal protein S18, score 5.4e-32
862962015813	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
862962015814	HMMPfam hit to PF01250, Ribosomal protein S6, score 2.3e-28
862962015815	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
862962015816	MarR family; Region: MarR_2; pfam12802
862962015817	HMMPfam hit to PF01047, MarR family, score 2.7e-16
862962015818	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962015819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962015820	active site
862962015821	phosphorylation site [posttranslational modification]
862962015822	intermolecular recognition site; other site
862962015823	dimerization interface [polypeptide binding]; other site
862962015824	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
862962015825	DNA binding site [nucleotide binding]
862962015826	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.6e-18
862962015827	HMMPfam hit to PF00072, Response regulator receiver domain, score 4.6e-33
862962015828	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962015829	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962015830	dimer interface [polypeptide binding]; other site
862962015831	phosphorylation site [posttranslational modification]
862962015832	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962015833	ATP binding site [chemical binding]; other site
862962015834	Mg2+ binding site [ion binding]; other site
862962015835	G-X-G motif; other site
862962015836	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.3e-34
862962015837	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.7e-15
862962015838	2 probable transmembrane helices predicted for BF638R3709 by TMHMM2.0 at aa 5-27 and 259-281
862962015839	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
862962015840	elongation factor G; Reviewed; Region: PRK12740
862962015841	G1 box; other site
862962015842	putative GEF interaction site [polypeptide binding]; other site
862962015843	GTP/Mg2+ binding site [chemical binding]; other site
862962015844	Switch I region; other site
862962015845	G2 box; other site
862962015846	G3 box; other site
862962015847	Switch II region; other site
862962015848	G4 box; other site
862962015849	G5 box; other site
862962015850	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
862962015851	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
862962015852	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
862962015853	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.7e-32
862962015854	HMMPfam hit to PF03764, Elongation factor G, domain IV, score 7.3e-37
862962015855	HMMPfam hit to PF03144, Elongation factor Tu domain, score 7.1e-06
862962015856	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.5e-32
862962015857	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015858	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
862962015859	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962015860	FeS/SAM binding site; other site
862962015861	HemN C-terminal domain; Region: HemN_C; pfam06969
862962015862	HMMPfam hit to PF04055, Radical SAM superfamily, score 2.2e-28
862962015863	HMMPfam hit to PF06969, HemN C-terminal region, score 1.4e-16
862962015864	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962015865	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962015866	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962015867	DNA binding residues [nucleotide binding]
862962015868	HMMPfam hit to PF04542, Sigma-70 region, score 0.00026
862962015869	Signal peptide predicted for BF638R3715 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.467 between residues 21 and 22
862962015870	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962015871	FecR protein; Region: FecR; pfam04773
862962015872	1 probable transmembrane helix predicted for BF638R3716 by TMHMM2.0 at aa 46-68
862962015873	HMMPfam hit to PF04773, FecR protein, score 3.8e-24
862962015874	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962015875	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962015876	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962015877	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962015878	Signal peptide predicted for BF638R3717 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.975 between residues 29 and 30
862962015879	1 probable transmembrane helix predicted for BF638R3717 by TMHMM2.0 at aa 13-30
862962015880	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 4.7e-09
862962015881	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3e-14
862962015882	HMMPfam hit to PF00593, TonB dependent receptor, score 1.8e-17
862962015883	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015884	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
862962015885	Signal peptide predicted for BF638R3718 by SignalP 2.0 HMM (Signal peptide probability 0.978) with cleavage site probability 0.709 between residues 22 and 23
862962015886	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015887	3 probable transmembrane helices predicted for BF638R3719 by TMHMM2.0 at aa 4-18, 25-47 and 62-84
862962015888	Membrane protein of unknown function (DUF340); Region: DUF340; pfam03956
862962015889	HMMPfam hit to PF03956, Membrane protein of unknown function (DUF340, score 5.4e-37
862962015890	5 probable transmembrane helices predicted for BF638R3720 by TMHMM2.0 at aa 5-25, 32-50, 65-87, 133-155 and 175-197
862962015891	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015892	Signal peptide predicted for BF638R3721 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.528 between residues 20 and 21
862962015893	Archaeal ATPase; Region: Arch_ATPase; pfam01637
862962015894	HMMPfam hit to PF01637, Archaeal ATPase, score 3.5e-05
862962015895	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
862962015896	3 probable transmembrane helices predicted for BF638R3723 by TMHMM2.0 at aa 20-42, 64-86 and 93-110
862962015897	Domain of unknown function (DUF2027); Region: DUF2027; pfam09640
862962015898	Smr domain; Region: Smr; pfam01713
862962015899	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
862962015900	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
862962015901	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 1.4e-60
862962015902	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
862962015903	nudix motif; other site
862962015904	HMMPfam hit to PF00293, NUDIX domain, score 1.6e-13
862962015905	PS00893 mutT domain signature.
862962015906	PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1.
862962015907	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
862962015908	catalytic residues [active]
862962015909	dimer interface [polypeptide binding]; other site
862962015910	HMMPfam hit to PF00255, Glutathione peroxidase, score 8e-52
862962015911	PS00460 Glutathione peroxidases selenocysteine active site.
862962015912	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
862962015913	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
862962015914	Signal peptide predicted for BF638R3728 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.970 between residues 20 and 21
862962015915	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
862962015916	Outer membrane efflux protein; Region: OEP; pfam02321
862962015917	Outer membrane efflux protein; Region: OEP; pfam02321
862962015918	Signal peptide predicted for BF638R3729 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.700 between residues 30 and 31
862962015919	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0
862962015920	13 probable transmembrane helices predicted for BF638R3729 by TMHMM2.0 at aa 13-35, 338-360, 367-389, 399-421, 444-466, 481-503, 541-563, 872-894, 901-920, 930-952, 975-997, 1007-1029 and 1049-1066
862962015921	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962015922	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962015923	Signal peptide predicted for BF638R3730 by SignalP 2.0 HMM (Signal peptide probability 0.839) with cleavage site probability 0.572 between residues 33 and 34
862962015924	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015925	Histidine kinase; Region: His_kinase; pfam06580
862962015926	4 probable transmembrane helices predicted for BF638R3731 by TMHMM2.0 at aa 21-43, 63-85, 97-119 and 134-156
862962015927	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015928	HMMPfam hit to PF06580, Histidine kinase, score 1.5e-37
862962015929	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962015930	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962015931	active site
862962015932	phosphorylation site [posttranslational modification]
862962015933	intermolecular recognition site; other site
862962015934	dimerization interface [polypeptide binding]; other site
862962015935	LytTr DNA-binding domain; Region: LytTR; pfam04397
862962015936	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.7e-14
862962015937	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 6.1e-27
862962015938	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
862962015939	4Fe-4S binding domain; Region: Fer4; cl02805
862962015940	4Fe-4S binding domain; Region: Fer4; pfam00037
862962015941	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
862962015942	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.6e-07
862962015943	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962015944	PS00190 Cytochrome c family heme-binding site signature.
862962015945	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 3.2e-09
862962015946	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962015947	HMMPfam hit to PF02906, Iron only hydrogenase large subunit, C-te, score 1.1e-13
862962015948	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
862962015949	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962015950	FeS/SAM binding site; other site
862962015951	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
862962015952	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.3e-08
862962015953	[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Region: rSAM_HydG; TIGR03955
862962015954	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962015955	FeS/SAM binding site; other site
862962015956	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
862962015957	HMMPfam hit to PF04055, Radical SAM superfamily, score 2e-10
862962015958	HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 6.5e-38
862962015959	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
862962015960	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
862962015961	G1 box; other site
862962015962	GTP/Mg2+ binding site [chemical binding]; other site
862962015963	Switch I region; other site
862962015964	G2 box; other site
862962015965	Switch II region; other site
862962015966	G3 box; other site
862962015967	G4 box; other site
862962015968	G5 box; other site
862962015969	HMMPfam hit to PF01926, GTPase of unknown function, score 7.3e-34
862962015970	PS00017 ATP/GTP-binding site motif A (P-loop).
862962015971	Signal peptide predicted for BF638R3737 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.915 between residues 24 and 25
862962015972	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015973	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
862962015974	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962015975	sugar binding site [chemical binding]; other site
862962015976	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 7.8e-183
862962015977	Signal peptide predicted for BF638R3738 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 18 and 19
862962015978	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
862962015979	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
862962015980	active site
862962015981	substrate binding site [chemical binding]; other site
862962015982	metal binding site [ion binding]; metal-binding site
862962015983	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 3.1e-11
862962015984	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 0.0018
862962015985	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 3.1e-08
862962015986	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 5e-27
862962015987	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015988	Signal peptide predicted for BF638R3740 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.615 between residues 20 and 21
862962015989	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
862962015990	DHH family; Region: DHH; pfam01368
862962015991	HMMPfam hit to PF01368, DHH family, score 4.4e-15
862962015992	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
862962015993	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
862962015994	Competence protein; Region: Competence; pfam03772
862962015995	10 probable transmembrane helices predicted for BF638R3742 by TMHMM2.0 at aa 10-32, 39-56, 60-82, 262-284, 294-316, 336-358, 393-415, 422-444, 485-507 and 514-531
862962015996	HMMPfam hit to PF03772, Competence protein, score 6.2e-37
862962015997	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962015998	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962015999	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
862962016000	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
862962016001	substrate binding site [chemical binding]; other site
862962016002	hexamer interface [polypeptide binding]; other site
862962016003	metal binding site [ion binding]; metal-binding site
862962016004	HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase family, score 1.5e-100
862962016005	PS01086 Ribulose-phosphate 3-epimerase family signature 2.
862962016006	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
862962016007	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
862962016008	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
862962016009	putative active site [active]
862962016010	substrate binding site [chemical binding]; other site
862962016011	putative cosubstrate binding site; other site
862962016012	catalytic site [active]
862962016013	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
862962016014	substrate binding site [chemical binding]; other site
862962016015	HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 1e-18
862962016016	HMMPfam hit to PF00551, Formyl transferase, score 2.5e-41
862962016017	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
862962016018	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
862962016019	Cl- selectivity filter; other site
862962016020	Cl- binding residues [ion binding]; other site
862962016021	pore gating glutamate residue; other site
862962016022	dimer interface [polypeptide binding]; other site
862962016023	FOG: CBS domain [General function prediction only]; Region: COG0517
862962016024	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc2; cd04613
862962016025	HMMPfam hit to PF00571, CBS domain, score 7.7e-06
862962016026	HMMPfam hit to PF00571, CBS domain, score 5e-09
862962016027	HMMPfam hit to PF00654, Voltage gated chloride channel, score 2e-30
862962016028	11 probable transmembrane helices predicted for BF638R3745 by TMHMM2.0 at aa 26-45, 65-84, 115-134, 159-181, 194-216, 236-253, 274-293, 319-341, 346-368, 388-410 and 415-437
862962016029	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016030	Signal peptide predicted for BF638R3745 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.977 between residues 41 and 42
862962016031	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
862962016032	HMMPfam hit to PF01300, yrdC domain, score 9.2e-27
862962016033	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
862962016034	active site
862962016035	HMMPfam hit to PF03061, Thioesterase superfamily, score 3.6e-08
862962016036	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
862962016037	Signal peptide predicted for BF638R3748 by SignalP 2.0 HMM (Signal peptide probability 0.973) with cleavage site probability 0.462 between residues 24 and 25
862962016038	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962016039	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
862962016040	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
862962016041	Mg++ binding site [ion binding]; other site
862962016042	putative catalytic motif [active]
862962016043	putative substrate binding site [chemical binding]; other site
862962016044	Similar to PS_5/PS_D lipopolysaccharide biosynthesis locus in BF9343
862962016045	11 probable transmembrane helices predicted for BF638R3750 by TMHMM2.0 at aa 4-21, 42-59, 63-80, 92-109, 113-132, 139-161, 165-182, 189-211, 218-240, 261-283 and 287-306
862962016046	HMMPfam hit to PF00953, Glycosyl transferase, score 1.8e-08
862962016047	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962016048	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962016049	NAD(P) binding site [chemical binding]; other site
862962016050	active site
862962016051	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962016052	NAD(P) binding site [chemical binding]; other site
862962016053	active site
862962016054	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962016055	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962016056	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962016057	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962016058	active site
862962016059	homodimer interface [polypeptide binding]; other site
862962016060	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 4.5e-156
862962016061	9 probable transmembrane helices predicted for BF638R3756 by TMHMM2.0 at aa 46-63, 97-119, 148-170, 201-220, 232-254, 269-291, 327-349, 364-383 and 390-412
862962016062	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
862962016063	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
862962016064	10 probable transmembrane helices predicted for BF638R3757 by TMHMM2.0 at aa 20-42, 57-76, 89-111, 121-143, 155-177, 182-204, 301-323, 338-360, 367-389 and 393-415
862962016065	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016066	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 8e-06
862962016067	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
862962016068	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
862962016069	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962016070	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962016071	active site
862962016072	HMMPfam hit to PF00535, Glycosyl transferase, score 7.8e-35
862962016073	pseudaminic acid synthase; Region: PseI; TIGR03586
862962016074	NeuB family; Region: NeuB; pfam03102
862962016075	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
862962016076	NeuB binding interface [polypeptide binding]; other site
862962016077	putative substrate binding site [chemical binding]; other site
862962016078	HMMPfam hit to PF01354, Antifreeze-like domain, score 4.7e-15
862962016079	HMMPfam hit to PF03102, NeuB family, score 6.5e-110
862962016080	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
862962016081	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
862962016082	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
862962016083	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.7e-10
862962016084	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
862962016085	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
862962016086	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
862962016087	catalytic residue [active]
862962016088	HMMPfam hit to PF00202, Aminotransferase class-III, score 1.7e-20
862962016089	SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat; Region: GT2_SpsF; cd02518
862962016090	ligand binding site; other site
862962016091	HMMPfam hit to PF02348, Cytidylyltransferase, score 2.7e-22
862962016092	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962016093	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
862962016094	active site
862962016095	catalytic tetrad [active]
862962016096	HMMPfam hit to PF00248, Aldo/keto reductase family, score 7.5e-08
862962016097	PS00228 Tubulin-beta mRNA autoregulation signal.
862962016098	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
862962016099	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
862962016100	inhibitor-cofactor binding pocket; inhibition site
862962016101	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962016102	catalytic residue [active]
862962016103	HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 3.2e-121
862962016104	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
862962016105	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962016106	NAD(P) binding site [chemical binding]; other site
862962016107	active site
862962016108	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 4.2e-07
862962016109	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962016110	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
862962016111	NAD(P) binding site [chemical binding]; other site
862962016112	active site
862962016113	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
862962016114	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
862962016115	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
862962016116	NAD(P) binding site [chemical binding]; other site
862962016117	homodimer interface [polypeptide binding]; other site
862962016118	substrate binding site [chemical binding]; other site
862962016119	active site
862962016120	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
862962016121	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 5e-10
862962016122	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
862962016123	UpxZ family of transcription anti-terminator antagonists; Region: UpxZ; pfam06603
862962016124	HMMPfam hit to PF06603, Protein of unknown function (DUF1141), score 7.3e-77
862962016125	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962016126	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
862962016127	HMMPfam hit to PF00467, KOW motif, score 0.0037
862962016128	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
862962016129	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
862962016130	HMMPfam hit to PF03352, Methyladenine glycosylase, score 2e-95
862962016131	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
862962016132	DHH family; Region: DHH; pfam01368
862962016133	DHHA1 domain; Region: DHHA1; pfam02272
862962016134	HMMPfam hit to PF01368, DHH family, score 3.8e-47
862962016135	HMMPfam hit to PF02272, DHHA1 domain, score 1.4e-12
862962016136	DEAD-like helicases superfamily; Region: DEXDc; smart00487
862962016137	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962016138	ATP binding site [chemical binding]; other site
862962016139	putative Mg++ binding site [ion binding]; other site
862962016140	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962016141	nucleotide binding region [chemical binding]; other site
862962016142	ATP-binding site [chemical binding]; other site
862962016143	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
862962016144	putative DNA binding site [nucleotide binding]; other site
862962016145	putative Zn2+ binding site [ion binding]; other site
862962016146	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.7e-32
862962016147	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1e-26
862962016148	TPR repeat; Region: TPR_11; pfam13414
862962016149	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962016150	binding surface
862962016151	TPR motif; other site
862962016152	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962016153	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962016154	binding surface
862962016155	TPR motif; other site
862962016156	TPR repeat; Region: TPR_11; pfam13414
862962016157	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962016158	TPR motif; other site
862962016159	TPR repeat; Region: TPR_11; pfam13414
862962016160	binding surface
862962016161	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.045
862962016162	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00011
862962016163	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 3.4
862962016164	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.093; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0035
862962016165	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.17
862962016166	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0024; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0016
862962016167	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.59; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.093
862962016168	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 3.9e-07; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.2e-05
862962016169	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0018; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.036
862962016170	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962016171	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962016172	putative substrate translocation pore; other site
862962016173	HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.0002
862962016174	12 probable transmembrane helices predicted for BF638R3783 by TMHMM2.0 at aa 7-29, 49-71, 78-97, 103-125, 138-160, 164-186, 207-229, 258-280, 293-312, 316-333, 354-376 and 381-403
862962016175	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.6e-47
862962016176	PS00217 Sugar transport proteins signature 2.
862962016177	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
862962016178	catalytic site [active]
862962016179	BNR repeat-like domain; Region: BNR_2; pfam13088
862962016180	Asp-box motif; other site
862962016181	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 7.6
862962016182	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 23
862962016183	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.4
862962016184	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 4.7
862962016185	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
862962016186	Asp-box motif; other site
862962016187	catalytic site [active]
862962016188	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.23
862962016189	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.44
862962016190	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.073
862962016191	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 4.5
862962016192	Signal peptide predicted for BF638R3785 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.903 between residues 31 and 32
862962016193	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962016194	Signal peptide predicted for BF638R3786 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.584 between residues 27 and 28
862962016195	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016196	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962016197	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962016198	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962016199	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962016200	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962016201	HMMPfam hit to PF00593, TonB dependent receptor, score 4.4e-08
862962016202	PS00018 EF-hand calcium-binding domain.
862962016203	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.1e-12
862962016204	Signal peptide predicted for BF638R3787 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27
862962016205	1 probable transmembrane helix predicted for BF638R3787 by TMHMM2.0 at aa 7-26
862962016206	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
862962016207	Class I aldolases; Region: Aldolase_Class_I; cl17187
862962016208	catalytic residue [active]
862962016209	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 6.5e-54
862962016210	PS00636 Nt-dnaJ domain signature.
862962016211	PS00665 Dihydrodipicolinate synthetase signature 1.
862962016212	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
862962016213	DNA-binding site [nucleotide binding]; DNA binding site
862962016214	Transcriptional regulators [Transcription]; Region: FadR; COG2186
862962016215	FCD domain; Region: FCD; pfam07729
862962016216	HMMPfam hit to PF07729, FCD domain, score 0.0001
862962016217	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.7e-13
862962016218	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
862962016219	Prephenate dehydratase; Region: PDT; pfam00800
862962016220	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
862962016221	putative L-Phe binding site [chemical binding]; other site
862962016222	HMMPfam hit to PF00800, Prephenate dehydratase, score 6.8e-35
862962016223	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016224	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
862962016225	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962016226	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962016227	homodimer interface [polypeptide binding]; other site
862962016228	catalytic residue [active]
862962016229	HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.4e-25
862962016230	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
862962016231	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
862962016232	Chorismate mutase type II; Region: CM_2; smart00830
862962016233	HMMPfam hit to PF00793, DAHP synthetase I family, score 4.5e-23
862962016234	HMMPfam hit to PF01817, Chorismate mutase type II, score 5.3e-17
862962016235	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
862962016236	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
862962016237	prephenate dehydrogenase; Validated; Region: PRK08507
862962016238	HMMPfam hit to PF02153, Prephenate dehydrogenase, score 4.8e-08
862962016239	DNA primase, catalytic core; Region: dnaG; TIGR01391
862962016240	CHC2 zinc finger; Region: zf-CHC2; pfam01807
862962016241	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
862962016242	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
862962016243	active site
862962016244	metal binding site [ion binding]; metal-binding site
862962016245	interdomain interaction site; other site
862962016246	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
862962016247	HMMPfam hit to PF01807, CHC2 zinc finger, score 1.1e-48
862962016248	HMMPfam hit to PF01751, Toprim domain, score 4.6e-17
862962016249	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962016250	Sulfatase; Region: Sulfatase; pfam00884
862962016251	HMMPfam hit to PF00884, Sulfatase, score 3.2e-41
862962016252	PS00149 Sulfatases signature 2.
862962016253	Signal peptide predicted for BF638R3796 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.937 between residues 19 and 20
862962016254	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962016255	Sulfatase; Region: Sulfatase; pfam00884
862962016256	HMMPfam hit to PF00884, Sulfatase, score 2.2e-45
862962016257	PS00149 Sulfatases signature 2.
862962016258	PS00523 Sulfatases signature 1.
862962016259	Signal peptide predicted for BF638R3797 by SignalP 2.0 HMM (Signal peptide probability 0.934) with cleavage site probability 0.824 between residues 42 and 43
862962016260	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962016261	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962016262	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016263	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962016264	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962016265	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962016266	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962016267	HMMPfam hit to PF00593, TonB dependent receptor, score 1.5e-16
862962016268	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.1e-19
862962016269	Signal peptide predicted for BF638R3799 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.806 between residues 45 and 46
862962016270	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962016271	FecR protein; Region: FecR; pfam04773
862962016272	HMMPfam hit to PF04773, FecR protein, score 2.1e-26
862962016273	1 probable transmembrane helix predicted for BF638R3800 by TMHMM2.0 at aa 70-92
862962016274	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962016275	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962016276	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962016277	DNA binding residues [nucleotide binding]
862962016278	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-08
862962016279	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
862962016280	homodecamer interface [polypeptide binding]; other site
862962016281	GTP cyclohydrolase I; Provisional; Region: PLN03044
862962016282	active site
862962016283	putative catalytic site residues [active]
862962016284	zinc binding site [ion binding]; other site
862962016285	GTP-CH-I/GFRP interaction surface; other site
862962016286	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 3.3e-48
862962016287	Sporulation related domain; Region: SPOR; pfam05036
862962016288	Signal peptide predicted for BF638R3803 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.928 between residues 19 and 20
862962016289	triosephosphate isomerase; Provisional; Region: PRK14567
862962016290	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
862962016291	substrate binding site [chemical binding]; other site
862962016292	dimer interface [polypeptide binding]; other site
862962016293	catalytic triad [active]
862962016294	HMMPfam hit to PF00121, Triosephosphate isomerase, score 2.9e-127
862962016295	PS00171 Triosephosphate isomerase active site.
862962016296	DoxX; Region: DoxX; pfam07681
862962016297	6 probable transmembrane helices predicted for BF638R3805 by TMHMM2.0 at aa 12-31, 61-83, 90-112, 127-144, 161-183 and 397-419
862962016298	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
862962016299	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
862962016300	HMMPfam hit to PF07659, Domain of Unknown Function (DUF1599), score 1e-35
862962016301	HMMPfam hit to PF07659, Domain of Unknown Function (DUF1599), score 9.6e-42
862962016302	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
862962016303	Peptidase family M23; Region: Peptidase_M23; pfam01551
862962016304	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
862962016305	HMMPfam hit to PF01476, LysM domain, score 7.2e-14
862962016306	HMMPfam hit to PF01551, Peptidase family M23, score 4.9e-47
862962016307	Signal peptide predicted for BF638R3807 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 23 and 24
862962016308	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
862962016309	active site
862962016310	multimer interface [polypeptide binding]; other site
862962016311	HMMPfam hit to PF00334, Nucleoside diphosphate kinase, score 2.2e-53
862962016312	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
862962016313	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
862962016314	generic binding surface II; other site
862962016315	ssDNA binding site; other site
862962016316	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962016317	ATP binding site [chemical binding]; other site
862962016318	putative Mg++ binding site [ion binding]; other site
862962016319	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962016320	nucleotide binding region [chemical binding]; other site
862962016321	ATP-binding site [chemical binding]; other site
862962016322	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.1e-20
862962016323	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 4e-34
862962016324	PS00435 Peroxidases proximal heme-ligand signature.
862962016325	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016326	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 0.00064
862962016327	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
862962016328	substrate binding site; other site
862962016329	dimer interface; other site
862962016330	HMMPfam hit to PF01128, Uncharacterized protein family UPF0007, score 1.7e-44
862962016331	DJ-1 family protein; Region: not_thiJ; TIGR01383
862962016332	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
862962016333	conserved cys residue [active]
862962016334	HMMPfam hit to PF01965, DJ-1/PfpI family, score 6.7e-38
862962016335	Gram-negative bacterial tonB protein; Region: TonB; cl10048
862962016336	PS00430 TonB-dependent receptor proteins signature 1.
862962016337	1 probable transmembrane helix predicted for BF638R3812 by TMHMM2.0 at aa 12-34
862962016338	Signal peptide predicted for BF638R3812 by SignalP 2.0 HMM (Signal peptide probability 0.785) with cleavage site probability 0.627 between residues 32 and 33
862962016339	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
862962016340	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
862962016341	HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 2.6e-06
862962016342	1 probable transmembrane helix predicted for BF638R3813 by TMHMM2.0 at aa 20-42
862962016343	Signal peptide predicted for BF638R3813 by SignalP 2.0 HMM (Signal peptide probability 0.974) with cleavage site probability 0.417 between residues 41 and 42
862962016344	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
862962016345	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 6.3e-26
862962016346	3 probable transmembrane helices predicted for BF638R3814 by TMHMM2.0 at aa 43-62, 142-164 and 191-213
862962016347	Signal peptide predicted for BF638R3814 by SignalP 2.0 HMM (Signal peptide probability 0.601) with cleavage site probability 0.549 between residues 21 and 22
862962016348	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
862962016349	active site
862962016350	hydrophilic channel; other site
862962016351	dimerization interface [polypeptide binding]; other site
862962016352	catalytic residues [active]
862962016353	active site lid [active]
862962016354	HMMPfam hit to PF03740, Pyridoxal phosphate biosynthesis protein Pdx, score 2.5e-89
862962016355	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK01911
862962016356	ATP-NAD kinase; Region: NAD_kinase; pfam01513
862962016357	HMMPfam hit to PF01513, ATP-NAD kinase, score 3.9e-70
862962016358	3 probable transmembrane helices predicted for BF638R3817 by TMHMM2.0 at aa 96-118, 138-155 and 181-199
862962016359	2 probable transmembrane helices predicted for BF638R3818 by TMHMM2.0 at aa 13-35 and 39-61
862962016360	Signal peptide predicted for BF638R3818 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.839 between residues 35 and 36
862962016361	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962016362	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962016363	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962016364	DNA binding residues [nucleotide binding]
862962016365	HMMPfam hit to PF04542, Sigma-70 region, score 5e-08
862962016366	HMMPfam hit to PF04545, Sigma-70, region, score 3.2e-15
862962016367	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962016368	FecR protein; Region: FecR; pfam04773
862962016369	fec operon regulator FecR; Reviewed; Region: PRK09774
862962016370	1 probable transmembrane helix predicted for BF638R3820 by TMHMM2.0 at aa 76-98
862962016371	HMMPfam hit to PF04773, FecR protein, score 3.8e-23
862962016372	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962016373	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962016374	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962016375	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962016376	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962016377	Signal peptide predicted for BF638R3821 by SignalP 2.0 HMM (Signal peptide probability 0.710) with cleavage site probability 0.579 between residues 40 and 41
862962016378	1 probable transmembrane helix predicted for BF638R3821 by TMHMM2.0 at aa 21-43
862962016379	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.2e-11
862962016380	HMMPfam hit to PF00593, TonB dependent receptor, score 1.3e-22
862962016381	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962016382	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962016383	SusD family; Region: SusD; pfam07980
862962016384	Signal peptide predicted for BF638R3822 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.700 between residues 25 and 26
862962016385	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016386	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
862962016387	Signal peptide predicted for BF638R3823 by SignalP 2.0 HMM (Signal peptide probability 0.927) with cleavage site probability 0.572 between residues 20 and 21
862962016388	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016389	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
862962016390	Endonuclease/Exonuclease/phosphatase family; Region: Exo_endo_phos; pfam03372
862962016391	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962016392	putative catalytic site [active]
862962016393	putative phosphate binding site [ion binding]; other site
862962016394	putative metal binding site [ion binding]; other site
862962016395	Signal peptide predicted for BF638R3824 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.813 between residues 22 and 23
862962016396	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 7.7e-05
862962016397	Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms]; Region: MecR1; COG4219
862962016398	4 probable transmembrane helices predicted for BF638R3825 by TMHMM2.0 at aa 10-29, 41-60, 129-151 and 304-326
862962016399	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
862962016400	Penicillinase repressor; Region: Pencillinase_R; pfam03965
862962016401	HMMPfam hit to PF03965, Penicillinase repressor, score 5e-42
862962016402	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962016403	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962016404	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
862962016405	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
862962016406	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962016407	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
862962016408	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
862962016409	Domain interface; other site
862962016410	Peptide binding site; other site
862962016411	Active site tetrad [active]
862962016412	HMMPfam hit to PF03572, Peptidase family S41, score 9.1e-25
862962016413	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962016414	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.22
862962016415	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.18
862962016416	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.1e-05
862962016417	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 3.9
862962016418	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 3.9e-05
862962016419	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.2e-06
862962016420	HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 3.1
862962016421	Signal peptide predicted for BF638R3827 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 19 and 20
862962016422	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
862962016423	malate dehydrogenase; Reviewed; Region: PRK06223
862962016424	dimer interface [polypeptide binding]; other site
862962016425	NAD(P) binding site [chemical binding]; other site
862962016426	tetramer (dimer of dimers) interface [polypeptide binding]; other site
862962016427	substrate binding site [chemical binding]; other site
862962016428	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 9.5e-32
862962016429	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 4.4e-49
862962016430	Signal peptide predicted for BF638R3828 by SignalP 2.0 HMM (Signal peptide probability 0.691) with cleavage site probability 0.518 between residues 21 and 22
862962016431	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
862962016432	Signal peptide predicted for BF638R3829 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.460 between residues 17 and 18
862962016433	1 probable transmembrane helix predicted for BF638R3829 by TMHMM2.0 at aa 5-27
862962016434	FecR protein; Region: FecR; pfam04773
862962016435	HMMPfam hit to PF04773, FecR protein, score 2.5e-28
862962016436	1 probable transmembrane helix predicted for BF638R3830 by TMHMM2.0 at aa 52-71
862962016437	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962016438	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962016439	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962016440	HMMPfam hit to PF04542, Sigma-70 region, score 2.2e-08
862962016441	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962016442	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962016443	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962016444	Signal peptide predicted for BF638R3832 by SignalP 2.0 HMM (Signal peptide probability 0.958) with cleavage site probability 0.764 between residues 27 and 28
862962016445	Outer membrane efflux protein; Region: OEP; pfam02321
862962016446	Outer membrane efflux protein; Region: OEP; pfam02321
862962016447	Signal peptide predicted for BF638R3833 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.401 between residues 19 and 20
862962016448	HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0042
862962016449	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.7e-28
862962016450	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
862962016451	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
862962016452	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962016453	1 probable transmembrane helix predicted for BF638R3834 by TMHMM2.0 at aa 12-34
862962016454	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962016455	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962016456	6 probable transmembrane helices predicted for BF638R3835 by TMHMM2.0 at aa 25-47, 197-219, 239-261, 276-298, 305-327 and 358-380
862962016457	PS00136 Serine proteases, subtilase family, aspartic acid active site.
862962016458	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
862962016459	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
862962016460	6 probable transmembrane helices predicted for BF638R3836 by TMHMM2.0 at aa 33-55, 197-219, 245-267, 282-304, 311-333 and 373-391
862962016461	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
862962016462	Signal peptide predicted for BF638R3837 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 53 and 54
862962016463	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_4; cd04501
862962016464	active site
862962016465	catalytic triad [active]
862962016466	oxyanion hole [active]
862962016467	Signal peptide predicted for BF638R3838 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.591 between residues 26 and 27
862962016468	1 probable transmembrane helix predicted for BF638R3838 by TMHMM2.0 at aa 5-27
862962016469	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 3.9e-13
862962016470	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
862962016471	active site
862962016472	catalytic triad [active]
862962016473	oxyanion hole [active]
862962016474	Signal peptide predicted for BF638R3839 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.973 between residues 20 and 21
862962016475	Penicillinase repressor; Region: Pencillinase_R; pfam03965
862962016476	HMMPfam hit to PF03965, Penicillinase repressor, score 1.5e-41
862962016477	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
862962016478	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
862962016479	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
862962016480	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
862962016481	4 probable transmembrane helices predicted for BF638R3841 by TMHMM2.0 at aa 5-27, 39-58, 93-115 and 274-296
862962016482	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 3.8e-07
862962016483	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 2.7e-07
862962016484	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962016485	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962016486	catalytic residues [active]
862962016487	Signal peptide predicted for BF638R3842 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.968 between residues 20 and 21
862962016488	PS00194 Thioredoxin family active site.
862962016489	Domain of unknown function DUF59; Region: DUF59; pfam01883
862962016490	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
862962016491	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016492	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
862962016493	HMMPfam hit to PF02390, Putative methyltransferase, score 8.9e-17
862962016494	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
862962016495	HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 6.8e-14
862962016496	PS00141 Eukaryotic and viral aspartyl proteases active site.
862962016497	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
862962016498	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
862962016499	homodimer interface [polypeptide binding]; other site
862962016500	substrate-cofactor binding pocket; other site
862962016501	catalytic residue [active]
862962016502	HMMPfam hit to PF01063, Aminotransferase class IV, score 5e-96
862962016503	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
862962016504	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
862962016505	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
862962016506	generic binding surface II; other site
862962016507	generic binding surface I; other site
862962016508	HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 1.9e-08
862962016509	Peptidase S8 family domain, uncharacterized subfamily 9; Region: Peptidases_S8_9; cd07493
862962016510	active site
862962016511	catalytic triad [active]
862962016512	HMMPfam hit to PF00082, Subtilase family, score 1.2e-13
862962016513	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016514	PS00138 Serine proteases, subtilase family, serine active site.
862962016515	Signal peptide predicted for BF638R3849 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.848 between residues 18 and 19
862962016516	tRNA-specific 2-thiouridylase MnmA; Provisional; Region: PRK14664
862962016517	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
862962016518	Ligand Binding Site [chemical binding]; other site
862962016519	HMMPfam hit to PF03054, tRNA methyl transferase, score 8.9e-108
862962016520	Signal peptide predicted for BF638R3850 by SignalP 2.0 HMM (Signal peptide probability 0.613) with cleavage site probability 0.321 between residues 37 and 38
862962016521	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962016522	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962016523	putative active site [active]
862962016524	putative metal binding site [ion binding]; other site
862962016525	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
862962016526	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 6.8e-15
862962016527	Signal peptide predicted for BF638R3854 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.768 between residues 22 and 23
862962016528	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
862962016529	homotrimer interaction site [polypeptide binding]; other site
862962016530	zinc binding site [ion binding]; other site
862962016531	CDP-binding sites; other site
862962016532	HMMPfam hit to PF02542, YgbB family, score 1.2e-85
862962016533	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
862962016534	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
862962016535	HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 4.5e-36
862962016536	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
862962016537	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
862962016538	CoA binding domain; Region: CoA_binding; pfam02629
862962016539	HMMPfam hit to PF06971, Putative DNA-binding protein C-terminu, score 2.2e-14
862962016540	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
862962016541	putative rRNA binding site [nucleotide binding]; other site
862962016542	HMMPfam hit to PF01253, Translation initiation factor SUI1, score 4e-17
862962016543	elongation factor Ts; Provisional; Region: tsf; PRK09377
862962016544	Elongation factor TS; Region: EF_TS; pfam00889
862962016545	Elongation factor TS; Region: EF_TS; pfam00889
862962016546	HMMPfam hit to PF00889, Elongation factor TS, score 6.6e-54
862962016547	HMMPfam hit to PF00627, UBA/TS-N domain, score 5.1e-09
862962016548	PS01126 Elongation factor Ts signature 1.
862962016549	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
862962016550	rRNA interaction site [nucleotide binding]; other site
862962016551	S8 interaction site; other site
862962016552	putative laminin-1 binding site; other site
862962016553	HMMPfam hit to PF00318, Ribosomal protein S2, score 9.3e-87
862962016554	PS00963 Ribosomal protein S2 signature 2.
862962016555	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
862962016556	HMMPfam hit to PF00380, Ribosomal protein S9/S16, score 2.1e-51
862962016557	PS00360 Ribosomal protein S9 signature.
862962016558	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
862962016559	23S rRNA interface [nucleotide binding]; other site
862962016560	HMMPfam hit to PF00572, Ribosomal protein L13, score 2.6e-54
862962016561	PS00783 Ribosomal protein L13 signature.
862962016562	Signal peptide predicted for BF638R3864 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.952 between residues 22 and 23
862962016563	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
862962016564	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
862962016565	putative dimer interface [polypeptide binding]; other site
862962016566	putative anticodon binding site; other site
862962016567	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
862962016568	homodimer interface [polypeptide binding]; other site
862962016569	motif 1; other site
862962016570	motif 2; other site
862962016571	active site
862962016572	motif 3; other site
862962016573	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 1.9e-117
862962016574	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962016575	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
862962016576	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.3e-14
862962016577	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
862962016578	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
862962016579	RNA binding surface [nucleotide binding]; other site
862962016580	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
862962016581	active site
862962016582	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 6.8e-10
862962016583	PS01149 Rsu family of pseudouridine synthase signature.
862962016584	HMMPfam hit to PF01479, S4 domain, score 1.5e-12
862962016585	adenylosuccinate lyase; Provisional; Region: PRK09285
862962016586	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
862962016587	tetramer interface [polypeptide binding]; other site
862962016588	active site
862962016589	HMMPfam hit to PF00206, Lyase, score 1.1e-39
862962016590	PS00163 Fumarate lyases signature.
862962016591	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
862962016592	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 3.7e-141
862962016593	PS01182 Glycosyl hydrolases family 35 putative active site.
862962016594	Signal peptide predicted for BF638R3868 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.799 between residues 21 and 22
862962016595	maltose O-acetyltransferase; Provisional; Region: PRK10092
862962016596	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
862962016597	active site
862962016598	substrate binding site [chemical binding]; other site
862962016599	trimer interface [polypeptide binding]; other site
862962016600	CoA binding site [chemical binding]; other site
862962016601	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.022
862962016602	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.081
862962016603	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3
862962016604	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 18
862962016605	hypothetical protein; Validated; Region: PRK02101
862962016606	HMMPfam hit to PF03883, Protein of unknown function (DUF328), score 1.7e-46
862962016607	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962016608	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
862962016609	Signal peptide predicted for BF638R3871 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.986 between residues 21 and 22
862962016610	HMMPfam hit to PF07555, Hyaluronidase, score 1.3e-168
862962016611	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962016612	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016613	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
862962016614	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016615	Calx-beta domain; Region: Calx-beta; cl02522
862962016616	1 probable transmembrane helix predicted for BF638R3875 by TMHMM2.0 at aa 9-28
862962016617	Signal peptide predicted for BF638R3875 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.988 between residues 25 and 26
862962016618	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016619	TPR repeat; Region: TPR_11; pfam13414
862962016620	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
862962016621	TPR motif; other site
862962016622	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962016623	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962016624	ligand binding site [chemical binding]; other site
862962016625	HMMPfam hit to PF00691, OmpA family, score 7e-07
862962016626	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00092
862962016627	Signal peptide predicted for BF638R3876 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 27 and 28
862962016628	1 probable transmembrane helix predicted for BF638R3876 by TMHMM2.0 at aa 7-26
862962016629	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962016630	1 probable transmembrane helix predicted for BF638R3877 by TMHMM2.0 at aa 7-26
862962016631	Signal peptide predicted for BF638R3877 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 23 and 24
862962016632	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962016633	1 probable transmembrane helix predicted for BF638R3878 by TMHMM2.0 at aa 7-29
862962016634	Signal peptide predicted for BF638R3878 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.608 between residues 24 and 25
862962016635	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016636	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962016637	Signal peptide predicted for BF638R3879 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.657 between residues 26 and 27
862962016638	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016639	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
862962016640	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962016641	active site
862962016642	DNA binding site [nucleotide binding]
862962016643	Int/Topo IB signature motif; other site
862962016644	HMMPfam hit to PF00589, Phage integrase family, score 1.2e-06
862962016645	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 0.14
862962016646	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
862962016647	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
862962016648	HMMPfam hit to PF04519, Protein of unknown function, DUF583, score 6.7e-26
862962016649	carbamoyl-phosphate synthase, large subunit; Region: CPSaseII_lrg; TIGR01369
862962016650	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962016651	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962016652	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
862962016653	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
862962016654	ATP-grasp domain; Region: ATP-grasp_4; cl17255
862962016655	Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain; Region: MGS_CPS_I_III; cd01423
862962016656	probable substrate binding site [chemical binding]; other site
862962016657	HMMPfam hit to PF02142, MGS-like domain, score 1.3e-28
862962016658	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 8.2e-12
862962016659	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962016660	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
862962016661	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 6.3e-13
862962016662	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 9.5e-55
862962016663	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 7.7e-113
862962016664	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962016665	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
862962016666	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 2.1e-60
862962016667	PS00430 TonB-dependent receptor proteins signature 1.
862962016668	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
862962016669	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
862962016670	active site
862962016671	HIGH motif; other site
862962016672	dimer interface [polypeptide binding]; other site
862962016673	KMSKS motif; other site
862962016674	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 5e-94
862962016675	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962016676	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962016677	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962016678	ligand binding site [chemical binding]; other site
862962016679	HMMPfam hit to PF00691, OmpA family, score 2.9e-10
862962016680	Signal peptide predicted for BF638R3885 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 19 and 20
862962016681	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
862962016682	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962016683	1 probable transmembrane helix predicted for BF638R3886 by TMHMM2.0 at aa 27-49
862962016684	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
862962016685	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
862962016686	putative active site [active]
862962016687	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
862962016688	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
862962016689	Walker A/P-loop; other site
862962016690	ATP binding site [chemical binding]; other site
862962016691	Q-loop/lid; other site
862962016692	ABC transporter signature motif; other site
862962016693	Walker B; other site
862962016694	D-loop; other site
862962016695	H-loop/switch region; other site
862962016696	HMMPfam hit to PF00005, ABC transporter, score 4.4e-53
862962016697	PS00211 ABC transporters family signature.
862962016698	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016699	5 probable transmembrane helices predicted for BF638R3887 by TMHMM2.0 at aa 177-199, 214-236, 287-309, 313-335 and 436-458
862962016700	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.3e-08
862962016701	HMMPfam hit to PF03412, Peptidase C39 family, score 2e-32
862962016702	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962016703	Sulfotransferase family; Region: Sulfotransfer_2; pfam03567
862962016704	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
862962016705	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
862962016706	active site
862962016707	HMMPfam hit to PF00535, Glycosyl transferase, score 1e-44
862962016708	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
862962016709	HMMPfam hit to PF00852, Glycosyltransferase family 10 (fucosy, score 3.7e-10
862962016710	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962016711	active site
862962016712	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
862962016713	ligand binding site; other site
862962016714	tetramer interface; other site
862962016715	pseudo-rSAM protein, GG-Bacteroidales system; Region: pseudo_rSAM_GG; TIGR04150
862962016716	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
862962016717	low GC content region
862962016718	radical SAM peptide maturase, GG-Bacteroidales family; Region: GG_samocin_CFB; TIGR04148
862962016719	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962016720	FeS/SAM binding site; other site
862962016721	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.1e-12
862962016722	Signal peptide predicted for BF638R3896 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.764 between residues 24 and 25
862962016723	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016724	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
862962016725	glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157
862962016726	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962016727	HMMPfam hit to PF00534, Glycosyl transferases group, score 5.7e-17
862962016728	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
862962016729	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962016730	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; pfam02709
862962016731	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962016732	Domain of unknown function (DUF3244); Region: DUF3244; pfam11589
862962016733	Signal peptide predicted for BF638R3902 by SignalP 2.0 HMM (Signal peptide probability 0.925) with cleavage site probability 0.818 between residues 20 and 21
862962016734	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962016735	1 probable transmembrane helix predicted for BF638R3903 by TMHMM2.0 at aa 362-384
862962016736	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.5
862962016737	Signal peptide predicted for BF638R3903 by SignalP 2.0 HMM (Signal peptide probability 0.920) with cleavage site probability 0.242 between residues 24 and 25
862962016738	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016739	Domain present in PSD-95, Dlg, and ZO-1/2; Region: PDZ; smart00228
862962016740	PS00136 Serine proteases, subtilase family, aspartic acid active site.
862962016741	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016742	1 probable transmembrane helix predicted for BF638R3904 by TMHMM2.0 at aa 12-31
862962016743	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
862962016744	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
862962016745	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
862962016746	Signal peptide predicted for BF638R3906 by SignalP 2.0 HMM (Signal peptide probability 0.851) with cleavage site probability 0.486 between residues 22 and 23
862962016747	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
862962016748	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962016749	glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157
862962016750	HMMPfam hit to PF00534, Glycosyl transferases group, score 5.7e-26
862962016752	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962016753	Archaea-specific editing domain of threonyl-tRNA synthetase; Region: tRNA-Thr_ED; pfam08915
862962016754	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962016755	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962016756	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
862962016757	dimer interface [polypeptide binding]; other site
862962016758	phosphorylation site [posttranslational modification]
862962016759	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962016760	ATP binding site [chemical binding]; other site
862962016761	Mg2+ binding site [ion binding]; other site
862962016762	G-X-G motif; other site
862962016763	2 probable transmembrane helices predicted for BF638R3913 by TMHMM2.0 at aa 5-24 and 201-223
862962016764	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016765	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0024
862962016766	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.1e-31
862962016767	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
862962016768	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962016769	active site
862962016770	phosphorylation site [posttranslational modification]
862962016771	intermolecular recognition site; other site
862962016772	dimerization interface [polypeptide binding]; other site
862962016773	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
862962016774	DNA binding site [nucleotide binding]
862962016775	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.2e-22
862962016776	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 5e-10
862962016777	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
862962016778	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962016779	Signal peptide predicted for BF638R3916 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.371 between residues 22 and 23
862962016780	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016781	Signal peptide predicted for BF638R3918 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.590 between residues 28 and 29
862962016782	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016783	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016784	Signal peptide predicted for BF638R3919 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.606 between residues 36 and 37
862962016785	1 probable transmembrane helix predicted for BF638R3920 by TMHMM2.0 at aa 5-27
862962016786	Signal peptide predicted for BF638R3920 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.616 between residues 24 and 25
862962016787	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016788	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962016789	Ubiquitin-like proteins; Region: UBQ; cl00155
862962016790	Ubiquitin homologues; Region: UBQ; smart00213
862962016791	charged pocket; other site
862962016792	hydrophobic patch; other site
862962016793	HMMPfam hit to PF00240, Ubiquitin family, score 3.9e-29
862962016794	1 probable transmembrane helix predicted for BF638R3924 by TMHMM2.0 at aa 42-64
862962016795	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
862962016796	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962016797	ATP binding site [chemical binding]; other site
862962016798	Mg2+ binding site [ion binding]; other site
862962016799	G-X-G motif; other site
862962016800	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
862962016801	ATP binding site [chemical binding]; other site
862962016802	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
862962016803	HMMPfam hit to PF01119, DNA mismatch repair protein, C-termina, score 1.2e-22
862962016804	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 0.0001
862962016805	PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature.
862962016806	1 probable transmembrane helix predicted for BF638R3926 by TMHMM2.0 at aa 72-91
862962016807	OstA-like protein; Region: OstA_2; pfam13100
862962016808	Rotavirus RNA-binding Protein 53 (NS53); Region: Rota_NS53; pfam00981
862962016809	OstA-like protein; Region: OstA; cl00844
862962016810	OstA-like protein; Region: OstA_2; pfam13100
862962016811	1 probable transmembrane helix predicted for BF638R3927 by TMHMM2.0 at aa 16-33
862962016812	Signal peptide predicted for BF638R3927 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 32 and 33
862962016813	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
862962016814	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
862962016815	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
862962016816	HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 2.5e-16
862962016817	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962016818	Signal peptide predicted for BF638R3928 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 25 and 26
862962016819	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
862962016820	Signal peptide predicted for BF638R3929 by SignalP 2.0 HMM (Signal peptide probability 0.905) with cleavage site probability 0.592 between residues 37 and 38
862962016821	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
862962016822	Signal peptide predicted for BF638R3930 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.606 between residues 20 and 21
862962016823	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
862962016824	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
862962016825	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
862962016826	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
862962016827	active site
862962016828	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 4.8e-199
862962016829	PS00487 IMP dehydrogenase / GMP reductase signature.
862962016830	HMMPfam hit to PF00571, CBS domain, score 8.4e-13
862962016831	HMMPfam hit to PF00571, CBS domain, score 1.7e-16
862962016832	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
862962016833	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962016834	ATP binding site [chemical binding]; other site
862962016835	putative Mg++ binding site [ion binding]; other site
862962016836	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
862962016837	nucleotide binding region [chemical binding]; other site
862962016838	ATP-binding site [chemical binding]; other site
862962016839	RQC domain; Region: RQC; pfam09382
862962016840	HRDC domain; Region: HRDC; pfam00570
862962016841	HMMPfam hit to PF00570, HRDC domain, score 1.9e-14
862962016842	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.5e-29
862962016843	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.2e-24
862962016844	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
862962016845	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
862962016846	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962016847	Walker A motif; other site
862962016848	ATP binding site [chemical binding]; other site
862962016849	Walker B motif; other site
862962016850	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
862962016851	HMMPfam hit to PF00004, ATPase family associated with various cell, score 3.2e-23
862962016852	HMMPfam hit to PF07724, ATPase family associated with various cell, score 1.2e-71
862962016853	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016854	HMMPfam hit to PF06689, ClpX C4-type zinc finger, score 2.8e-19
862962016855	Clp protease; Region: CLP_protease; pfam00574
862962016856	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
862962016857	oligomer interface [polypeptide binding]; other site
862962016858	active site residues [active]
862962016859	HMMPfam hit to PF00574, Clp protease, score 5.9e-112
862962016860	PS00382 Endopeptidase Clp histidine active site.
862962016861	trigger factor; Region: tig; TIGR00115
862962016862	HMMPfam hit to PF05697, Bacterial trigger factor protein (TF), score 1.1e-26
862962016863	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
862962016864	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
862962016865	HMMPfam hit to PF00076, RNA recognition motif. (a.k.a. RRM, RBD, or, score 4.9e-23
862962016866	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
862962016867	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
862962016868	Walker A/P-loop; other site
862962016869	ATP binding site [chemical binding]; other site
862962016870	Q-loop/lid; other site
862962016871	ABC transporter signature motif; other site
862962016872	Walker B; other site
862962016873	D-loop; other site
862962016874	H-loop/switch region; other site
862962016875	HMMPfam hit to PF00005, ABC transporter, score 1.9e-54
862962016876	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016877	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
862962016878	Permease; Region: Permease; pfam02405
862962016879	HMMPfam hit to PF02405, Domain of unknown function DUF140, score 9e-36
862962016880	PS00012 Phosphopantetheine attachment site.
862962016881	4 probable transmembrane helices predicted for BF638R3939 by TMHMM2.0 at aa 47-69, 84-106, 153-175 and 190-212
862962016882	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
862962016883	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
862962016884	Walker A/P-loop; other site
862962016885	ATP binding site [chemical binding]; other site
862962016886	Q-loop/lid; other site
862962016887	ABC transporter signature motif; other site
862962016888	Walker B; other site
862962016889	D-loop; other site
862962016890	H-loop/switch region; other site
862962016891	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016892	HMMPfam hit to PF00005, ABC transporter, score 1.8e-54
862962016893	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016894	PS00211 ABC transporters family signature.
862962016895	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962016896	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962016897	active site
862962016898	phosphorylation site [posttranslational modification]
862962016899	intermolecular recognition site; other site
862962016900	dimerization interface [polypeptide binding]; other site
862962016901	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
862962016902	DNA binding residues [nucleotide binding]
862962016903	dimerization interface [polypeptide binding]; other site
862962016904	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 4.7e-10
862962016905	PS00622 Bacterial regulatory proteins, luxR family signature.
862962016906	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.6e-23
862962016907	GTP-binding protein Der; Reviewed; Region: PRK00093
862962016908	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
862962016909	G1 box; other site
862962016910	GTP/Mg2+ binding site [chemical binding]; other site
862962016911	Switch I region; other site
862962016912	G2 box; other site
862962016913	Switch II region; other site
862962016914	G3 box; other site
862962016915	G4 box; other site
862962016916	G5 box; other site
862962016917	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
862962016918	G1 box; other site
862962016919	GTP/Mg2+ binding site [chemical binding]; other site
862962016920	Switch I region; other site
862962016921	G2 box; other site
862962016922	G3 box; other site
862962016923	Switch II region; other site
862962016924	G4 box; other site
862962016925	G5 box; other site
862962016926	HMMPfam hit to PF01926, GTPase of unknown function, score 8.9e-43
862962016927	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016928	HMMPfam hit to PF01926, GTPase of unknown function, score 3.7e-45
862962016929	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016930	GTPase Era; Reviewed; Region: era; PRK00089
862962016931	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
862962016932	G1 box; other site
862962016933	GTP/Mg2+ binding site [chemical binding]; other site
862962016934	Switch I region; other site
862962016935	G2 box; other site
862962016936	Switch II region; other site
862962016937	G3 box; other site
862962016938	G4 box; other site
862962016939	G5 box; other site
862962016940	KH domain; Region: KH_2; pfam07650
862962016941	HMMPfam hit to PF07650, KH domain, score 4e-26
862962016942	HMMPfam hit to PF01926, GTPase of unknown function, score 4.8e-33
862962016943	PS00017 ATP/GTP-binding site motif A (P-loop).
862962016944	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
862962016945	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
862962016946	dimer interface [polypeptide binding]; other site
862962016947	active site
862962016948	CoA binding pocket [chemical binding]; other site
862962016949	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
862962016950	HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 3.2e-06
862962016951	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
862962016952	FAD binding site [chemical binding]; other site
862962016953	HMMPfam hit to PF02219, Methylenetetrahydrofolate reductase, score 3.2e-36
862962016954	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
862962016955	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
862962016956	DNA polymerase III subunit delta'; Validated; Region: PRK08058
862962016957	PSP1 C-terminal conserved region; Region: PSP1; cl00770
862962016958	HMMPfam hit to PF04468, PSP1 C-terminal conserved region, score 3.4e-25
862962016959	gliding motility-associated lipoprotein GldH; Region: GldH_lipo; TIGR03511
862962016960	Signal peptide predicted for BF638R3950 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.812 between residues 20 and 21
862962016961	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016962	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
862962016963	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
862962016964	HMMPfam hit to PF01098, Cell cycle protein, score 3e-39
862962016965	12 probable transmembrane helices predicted for BF638R3951 by TMHMM2.0 at aa 12-34, 54-71, 78-97, 144-161, 182-204, 214-236, 243-260, 270-289, 296-313, 392-411, 424-446 and 456-475
862962016966	PS00428 Cell cycle proteins ftsW / rodA / spoVE signature.
862962016967	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
862962016968	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
862962016969	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
862962016970	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.4e-46
862962016971	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962016972	HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 4.8e-29
862962016973	1 probable transmembrane helix predicted for BF638R3952 by TMHMM2.0 at aa 13-32
862962016974	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
862962016975	4 probable transmembrane helices predicted for BF638R3953 by TMHMM2.0 at aa 9-31, 66-88, 109-131 and 141-163
862962016976	rod shape-determining protein MreC; Provisional; Region: PRK13922
862962016977	rod shape-determining protein MreC; Region: MreC; pfam04085
862962016978	HMMPfam hit to PF04085, rod shape-determining protein MreC, score 4.6e-20
862962016979	1 probable transmembrane helix predicted for BF638R3954 by TMHMM2.0 at aa 7-29
862962016980	rod shape-determining protein MreB; Provisional; Region: PRK13927
862962016981	MreB and similar proteins; Region: MreB_like; cd10225
862962016982	nucleotide binding site [chemical binding]; other site
862962016983	Mg binding site [ion binding]; other site
862962016984	putative protofilament interaction site [polypeptide binding]; other site
862962016985	RodZ interaction site [polypeptide binding]; other site
862962016986	HMMPfam hit to PF06723, MreB/Mbl protein, score 9.2e-142
862962016987	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
862962016988	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
862962016989	purine monophosphate binding site [chemical binding]; other site
862962016990	dimer interface [polypeptide binding]; other site
862962016991	putative catalytic residues [active]
862962016992	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
862962016993	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
862962016994	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 7.3e-89
862962016995	HMMPfam hit to PF02142, MGS-like domain, score 3.6e-47
862962016996	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
862962016997	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
862962016998	active site
862962016999	Zn binding site [ion binding]; other site
862962017000	HMMPfam hit to PF01431, Peptidase family M13, score 1.3e-75
862962017001	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962017002	HMMPfam hit to PF05649, Peptidase family M13, score 7.5e-144
862962017003	Signal peptide predicted for BF638R3957 by SignalP 2.0 HMM (Signal peptide probability 0.923) with cleavage site probability 0.599 between residues 21 and 22
862962017004	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017005	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
862962017006	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962017007	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962017008	ABC transporter; Region: ABC_tran_2; pfam12848
862962017009	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
862962017010	HMMPfam hit to PF00005, ABC transporter, score 1.4e-37
862962017011	PS00211 ABC transporters family signature.
862962017012	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017013	HMMPfam hit to PF00005, ABC transporter, score 2e-37
862962017014	PS00211 ABC transporters family signature.
862962017015	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017016	MG2 domain; Region: A2M_N; pfam01835
862962017017	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962017018	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962017019	Signal peptide predicted for BF638R3959 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.496 between residues 19 and 20
862962017020	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
862962017021	active site
862962017022	Surface antigen; Region: Bac_surface_Ag; pfam01103
862962017023	HMMPfam hit to PF01103, Surface antigen, score 6.8e-48
862962017024	1 probable transmembrane helix predicted for BF638R3961 by TMHMM2.0 at aa 16-38
862962017025	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017026	Family of unknown function (DUF490); Region: DUF490; pfam04357
862962017027	HMMPfam hit to PF04357, Family of unknown function (DUF490), score 0.00077
862962017028	1 probable transmembrane helix predicted for BF638R3962 by TMHMM2.0 at aa 7-29
862962017029	Signal peptide predicted for BF638R3962 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.454 between residues 27 and 28
862962017030	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962017031	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962017032	dimer interface [polypeptide binding]; other site
862962017033	phosphorylation site [posttranslational modification]
862962017034	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962017035	ATP binding site [chemical binding]; other site
862962017036	Mg2+ binding site [ion binding]; other site
862962017037	G-X-G motif; other site
862962017038	Response regulator receiver domain; Region: Response_reg; pfam00072
862962017039	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962017040	active site
862962017041	phosphorylation site [posttranslational modification]
862962017042	intermolecular recognition site; other site
862962017043	dimerization interface [polypeptide binding]; other site
862962017044	HMMPfam hit to PF00072, Response regulator receiver domain, score 4.4e-19
862962017045	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.8e-36
862962017046	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-13
862962017047	2 probable transmembrane helices predicted for BF638R3963 by TMHMM2.0 at aa 13-30 and 226-245
862962017048	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017049	Signal peptide predicted for BF638R3963 by SignalP 2.0 HMM (Signal peptide probability 0.719) with cleavage site probability 0.615 between residues 32 and 33
862962017050	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
862962017051	multidrug efflux protein; Reviewed; Region: PRK01766
862962017052	cation binding site [ion binding]; other site
862962017053	12 probable transmembrane helices predicted for BF638R3964 by TMHMM2.0 at aa 12-34, 54-76, 88-110, 130-147, 159-181, 191-213, 256-278, 283-302, 315-337, 350-367, 388-410 and 414-436
862962017054	HMMPfam hit to PF01554, MatE, score 1.3e-34
862962017055	HMMPfam hit to PF01554, MatE, score 4.7e-28
862962017056	Signal peptide predicted for BF638R3964 by SignalP 2.0 HMM (Signal peptide probability 0.663) with cleavage site probability 0.273 between residues 32 and 33
862962017057	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
862962017058	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
862962017059	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
862962017060	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 2.5e-41
862962017061	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 2.1e-06
862962017062	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
862962017063	active site
862962017064	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
862962017065	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 4.7e-18
862962017066	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
862962017067	Signal peptide predicted for BF638R3966 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.711 between residues 18 and 19
862962017068	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017069	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
862962017070	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962017071	active site
862962017072	phosphorylation site [posttranslational modification]
862962017073	intermolecular recognition site; other site
862962017074	dimerization interface [polypeptide binding]; other site
862962017075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962017076	Walker A motif; other site
862962017077	ATP binding site [chemical binding]; other site
862962017078	Walker B motif; other site
862962017079	arginine finger; other site
862962017080	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
862962017081	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.2e-32
862962017082	HMMPfam hit to PF00158, Sigma-54 interaction domain, score 2.8e-127
862962017083	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
862962017084	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.8e-15
862962017085	Signal peptide predicted for BF638R3969 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 49 and 50
862962017086	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017087	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
862962017088	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
862962017089	active site
862962017090	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 7e-33
862962017091	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
862962017092	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
862962017093	NAD(P) binding site [chemical binding]; other site
862962017094	homotetramer interface [polypeptide binding]; other site
862962017095	homodimer interface [polypeptide binding]; other site
862962017096	active site
862962017097	HMMPfam hit to PF00106, short chain dehydrogenase, score 3.9e-90
862962017098	PS00061 Short-chain dehydrogenases/reductases family signature.
862962017099	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962017100	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962017101	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1e-13
862962017102	Signal peptide predicted for BF638R3973 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.538 between residues 39 and 40
862962017103	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
862962017104	4 probable transmembrane helices predicted for BF638R3974 by TMHMM2.0 at aa 13-35, 60-82, 176-198 and 218-240
862962017105	HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 5.4e-16
862962017106	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
862962017107	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
862962017108	Signal peptide predicted for BF638R3975 by SignalP 2.0 HMM (Signal peptide probability 0.801) with cleavage site probability 0.457 between residues 38 and 39
862962017109	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
862962017110	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
862962017111	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
862962017112	1 probable transmembrane helix predicted for BF638R3977 by TMHMM2.0 at aa 38-57
862962017113	HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 2.7e-06
862962017114	PBP superfamily domain; Region: PBP_like_2; pfam12849
862962017115	Signal peptide predicted for BF638R3978 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.373 between residues 21 and 22
862962017116	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017117	TPR repeat; Region: TPR_11; pfam13414
862962017118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962017119	TPR motif; other site
862962017120	binding surface
862962017121	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962017122	binding surface
862962017123	TPR motif; other site
862962017124	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962017125	binding surface
862962017126	TPR motif; other site
862962017127	Signal peptide predicted for BF638R3979 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.633 between residues 20 and 21
862962017128	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.7; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.87
862962017129	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.73; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.042
862962017130	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.98; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.013
862962017131	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.0026; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0003
862962017132	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
862962017133	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
862962017134	Walker A/P-loop; other site
862962017135	ATP binding site [chemical binding]; other site
862962017136	Q-loop/lid; other site
862962017137	ABC transporter signature motif; other site
862962017138	Walker B; other site
862962017139	D-loop; other site
862962017140	H-loop/switch region; other site
862962017141	HMMPfam hit to PF00005, ABC transporter, score 4.2e-34
862962017142	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017143	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017144	6 probable transmembrane helices predicted for BF638R3981 by TMHMM2.0 at aa 26-48, 63-82, 107-129, 172-194, 201-223 and 238-260
862962017145	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
862962017146	DNA-binding site [nucleotide binding]; DNA binding site
862962017147	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.1e-09
862962017148	Signal peptide predicted for BF638R3983 by SignalP 2.0 HMM (Signal peptide probability 0.928) with cleavage site probability 0.692 between residues 21 and 22
862962017149	1 probable transmembrane helix predicted for BF638R3983 by TMHMM2.0 at aa 7-29
862962017150	Erythromycin esterase; Region: Erythro_esteras; cl17110
862962017151	Erythromycin esterase; Region: Erythro_esteras; cl17110
862962017152	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
862962017153	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
862962017154	Walker A/P-loop; other site
862962017155	ATP binding site [chemical binding]; other site
862962017156	Q-loop/lid; other site
862962017157	ABC transporter signature motif; other site
862962017158	Walker B; other site
862962017159	D-loop; other site
862962017160	H-loop/switch region; other site
862962017161	HMMPfam hit to PF00005, ABC transporter, score 2.7e-39
862962017162	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017163	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
862962017164	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
862962017165	7 probable transmembrane helices predicted for BF638R3986 by TMHMM2.0 at aa 22-44, 64-86, 93-115, 119-141, 154-176, 186-208 and 229-251
862962017166	Signal peptide predicted for BF638R3987 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.671 between residues 19 and 20
862962017167	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
862962017169	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
862962017170	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
862962017171	Transposase; Region: DDE_Tnp_ISL3; pfam01610
862962017172	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
862962017173	10 probable transmembrane helices predicted for BF638R3995 by TMHMM2.0 at aa 31-53, 60-74, 78-97, 109-128, 143-165, 338-355, 359-381, 394-412, 441-458 and 470-492
862962017174	HMMPfam hit to PF03062, MBOAT family, score 5.1e-79
862962017175	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962017176	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
862962017177	active site
862962017178	catalytic triad [active]
862962017179	oxyanion hole [active]
862962017180	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 0.0001
862962017181	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
862962017182	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
862962017183	active site
862962017184	oxyanion hole [active]
862962017185	catalytic triad [active]
862962017186	1 probable transmembrane helix predicted for BF638R3997 by TMHMM2.0 at aa 31-53
862962017187	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962017188	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 6.4e-257
862962017189	12 probable transmembrane helices predicted for BF638R3999 by TMHMM2.0 at aa 12-29, 332-351, 356-378, 382-404, 429-451, 461-483, 528-550, 865-882, 889-911, 921-943, 963-985 and 998-1020
862962017190	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962017191	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
862962017192	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962017193	Signal peptide predicted for BF638R4000 by SignalP 2.0 HMM (Signal peptide probability 0.969) with cleavage site probability 0.475 between residues 24 and 25
862962017194	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017195	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
862962017196	HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.6e-20
862962017197	HMMPfam hit to PF02321, Outer membrane efflux protein, score 9.3e-30
862962017198	Signal peptide predicted for BF638R4001 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 27 and 28
862962017199	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
862962017200	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
862962017201	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.7e-11
862962017202	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
862962017203	active sites [active]
862962017204	tetramer interface [polypeptide binding]; other site
862962017205	HMMPfam hit to PF00221, Phenylalanine and histidine ammonia-lyase, score 2.6e-162
862962017206	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
862962017207	HMMPfam hit to PF04961, Formiminotransferase-cyclodeaminase, score 1.7e-54
862962017208	imidazolonepropionase; Validated; Region: PRK09356
862962017209	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
862962017210	active site
862962017211	HMMPfam hit to PF01979, Amidohydrolase family, score 6.9e-06
862962017212	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017213	Glutamate formiminotransferase [Amino acid transport and metabolism]; Region: COG3643
862962017214	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
862962017215	Formiminotransferase domain; Region: FTCD; pfam02971
862962017216	HMMPfam hit to PF02971, Formiminotransferase domain, score 2.2e-34
862962017217	HMMPfam hit to PF07837, Formiminotransferase domain, N-terminal subd, score 2.1e-120
862962017218	urocanate hydratase; Provisional; Region: PRK05414
862962017219	HMMPfam hit to PF01175, Urocanase, score 2.8e-108
862962017220	Signal peptide predicted for BF638R4008 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.743 between residues 19 and 20
862962017221	MutS domain III; Region: MutS_III; pfam05192
862962017222	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
862962017223	ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283
862962017224	Walker A/P-loop; other site
862962017225	ATP binding site [chemical binding]; other site
862962017226	Q-loop/lid; other site
862962017227	ABC transporter signature motif; other site
862962017228	Walker B; other site
862962017229	D-loop; other site
862962017230	H-loop/switch region; other site
862962017231	3 probable transmembrane helices predicted for BF638R4010 by TMHMM2.0 at aa 32-51, 56-73 and 218-240
862962017232	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017233	HMMPfam hit to PF00488, MutS domain V, score 5.5e-13
862962017234	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017235	2 probable transmembrane helices predicted for BF638R4011 by TMHMM2.0 at aa 47-66 and 76-98
862962017236	Signal peptide predicted for BF638R4012 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.876 between residues 25 and 26
862962017237	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
862962017238	HMMPfam hit to PF01196, Ribosomal protein L17, score 2.5e-43
862962017239	PS01167 Ribosomal protein L17 signature.
862962017240	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
862962017241	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
862962017242	alphaNTD - beta interaction site [polypeptide binding]; other site
862962017243	alphaNTD homodimer interface [polypeptide binding]; other site
862962017244	alphaNTD - beta' interaction site [polypeptide binding]; other site
862962017245	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
862962017246	HMMPfam hit to PF03118, Bacterial RNA polymerase, alpha chain C, score 3.2e-15
862962017247	HMMPfam hit to PF01193, RNA polymerase Rpb3/Rpb11 dimerisation, score 2.2e-20
862962017248	HMMPfam hit to PF01000, RNA polymerase Rpb3/RpoA insert domain, score 4.8e-36
862962017249	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
862962017250	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
862962017251	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
862962017252	RNA binding surface [nucleotide binding]; other site
862962017253	HMMPfam hit to PF01479, S4 domain, score 1.4e-20
862962017254	PS00632 Ribosomal protein S4 signature.
862962017255	HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domai, score 1.1e-27
862962017256	30S ribosomal protein S11; Validated; Region: PRK05309
862962017257	HMMPfam hit to PF00411, Ribosomal protein S11, score 3.1e-54
862962017258	PS00054 Ribosomal protein S11 signature.
862962017259	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
862962017260	30S ribosomal protein S13; Region: bact_S13; TIGR03631
862962017261	HMMPfam hit to PF00416, Ribosomal protein S13/S18, score 6.4e-55
862962017262	PS00646 Ribosomal protein S13 signature.
862962017263	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
862962017264	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
862962017265	rRNA binding site [nucleotide binding]; other site
862962017266	predicted 30S ribosome binding site; other site
862962017267	HMMPfam hit to PF00575, S1 RNA binding domain, score 7.5e-11
862962017268	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
862962017269	active site
862962017270	HMMPfam hit to PF00557, metallopeptidase family M24, score 1.5e-66
862962017271	PS00680 Methionine aminopeptidase subfamily 1 signature.
862962017272	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
862962017273	SecY translocase; Region: SecY; pfam00344
862962017274	HMMPfam hit to PF00344, eubacterial secY protein, score 3e-135
862962017275	PS00307 Legume lectins beta-chain signature.
862962017276	10 probable transmembrane helices predicted for BF638R4020 by TMHMM2.0 at aa 21-43, 75-97, 117-136, 151-173, 180-202, 217-239, 270-292, 312-334, 369-391 and 396-413
862962017277	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
862962017278	PS00756 Protein secY signature 2.
862962017279	PS00755 Protein secY signature 1.
862962017280	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
862962017281	HMMPfam hit to PF00256, Ribosomal protein L15, score 3.8e-12
862962017282	PS00475 Ribosomal protein L15 signature.
862962017283	HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal re, score 4.5e-48
862962017284	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
862962017285	23S rRNA binding site [nucleotide binding]; other site
862962017286	HMMPfam hit to PF00327, Ribosomal protein L30p/L7e, score 2.4e-12
862962017287	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
862962017288	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
862962017289	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
862962017290	HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal domai, score 2.8e-26
862962017291	HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal domai, score 8.5e-32
862962017292	PS00585 Ribosomal protein S5 signature.
862962017293	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
862962017294	5S rRNA interface [nucleotide binding]; other site
862962017295	L27 interface [polypeptide binding]; other site
862962017296	23S rRNA interface [nucleotide binding]; other site
862962017297	L5 interface [polypeptide binding]; other site
862962017298	HMMPfam hit to PF00861, Ribosomal L18p/L5e family, score 2.4e-44
862962017299	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
862962017300	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
862962017301	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
862962017302	HMMPfam hit to PF00347, Ribosomal protein L6, score 1.3e-23
862962017303	PS00525 Ribosomal protein L6 signature 1.
862962017304	HMMPfam hit to PF00347, Ribosomal protein L6, score 1.4e-18
862962017305	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
862962017306	HMMPfam hit to PF00410, Ribosomal protein S8, score 7.4e-56
862962017307	This hit extended beyond the end of the feature by 1 aa and was clipped.; PS00294 Prenyl group binding site (CAAX box).
862962017308	PS00053 Ribosomal protein S8 signature.
862962017309	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
862962017310	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 1.2e-24
862962017311	PS00527 Ribosomal protein S14 signature.
862962017312	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
862962017313	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
862962017314	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
862962017315	HMMPfam hit to PF00673, ribosomal L5P family C-terminus, score 1.8e-47
862962017316	HMMPfam hit to PF00281, Ribosomal protein L5, score 8.1e-22
862962017317	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
862962017318	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
862962017319	RNA binding site [nucleotide binding]; other site
862962017320	HMMPfam hit to PF00467, KOW motif, score 1.3e-08
862962017321	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017322	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
862962017323	HMMPfam hit to PF00238, Ribosomal protein L14p/L23e, score 9.6e-71
862962017324	PS00049 Ribosomal protein L14 signature.
862962017325	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
862962017326	HMMPfam hit to PF00366, Ribosomal protein S17, score 6.1e-37
862962017327	PS00056 Ribosomal protein S17 signature.
862962017328	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
862962017329	23S rRNA interface [nucleotide binding]; other site
862962017330	putative translocon interaction site; other site
862962017331	signal recognition particle (SRP54) interaction site; other site
862962017332	L23 interface [polypeptide binding]; other site
862962017333	trigger factor interaction site; other site
862962017334	HMMPfam hit to PF00831, Ribosomal L29 protein, score 2e-13
862962017335	PS00579 Ribosomal protein L29 signature.
862962017336	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
862962017337	23S rRNA interface [nucleotide binding]; other site
862962017338	5S rRNA interface [nucleotide binding]; other site
862962017339	putative antibiotic binding site [chemical binding]; other site
862962017340	L25 interface [polypeptide binding]; other site
862962017341	L27 interface [polypeptide binding]; other site
862962017342	HMMPfam hit to PF00252, Ribosomal protein L16, score 7.3e-82
862962017343	PS00701 Ribosomal protein L16 signature 2.
862962017344	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
862962017345	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
862962017346	G-X-X-G motif; other site
862962017347	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
862962017348	HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal domai, score 1.2e-43
862962017349	PS00548 Ribosomal protein S3 signature.
862962017350	HMMPfam hit to PF07650, KH domain, score 3.6e-22
862962017351	HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal domai, score 7.7e-26
862962017352	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
862962017353	putative translocon binding site; other site
862962017354	protein-rRNA interface [nucleotide binding]; other site
862962017355	HMMPfam hit to PF00237, Ribosomal protein L22p/L17e, score 4.5e-28
862962017356	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
862962017357	HMMPfam hit to PF00203, Ribosomal protein S19, score 3.9e-46
862962017358	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
862962017359	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
862962017360	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
862962017361	HMMPfam hit to PF03947, Ribosomal Proteins L2, C-terminal doma, score 4.7e-73
862962017362	PS00467 Ribosomal protein L2 signature.
862962017363	HMMPfam hit to PF00181, Ribosomal Proteins L2, RNA binding dom, score 8.9e-40
862962017364	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
862962017365	HMMPfam hit to PF00276, Ribosomal protein L23, score 1.1e-20
862962017366	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
862962017367	HMMPfam hit to PF00573, Ribosomal protein L4/L1 family, score 8.2e-58
862962017368	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
862962017369	HMMPfam hit to PF00297, Ribosomal protein L3, score 2.6e-75
862962017370	PS00474 Ribosomal protein L3 signature.
862962017371	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
862962017372	HMMPfam hit to PF00338, Ribosomal protein S10p/S20e, score 1.9e-48
862962017373	PS00361 Ribosomal protein S10 signature.
862962017374	elongation factor G; Reviewed; Region: PRK12739
862962017375	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
862962017376	G1 box; other site
862962017377	putative GEF interaction site [polypeptide binding]; other site
862962017378	GTP/Mg2+ binding site [chemical binding]; other site
862962017379	Switch I region; other site
862962017380	G2 box; other site
862962017381	G3 box; other site
862962017382	Switch II region; other site
862962017383	G4 box; other site
862962017384	G5 box; other site
862962017385	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
862962017386	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
862962017387	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
862962017388	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 2.2e-41
862962017389	HMMPfam hit to PF03764, Elongation factor G, domain IV, score 8.8e-57
862962017390	HMMPfam hit to PF03144, Elongation factor Tu domain, score 5e-21
862962017391	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 2.4e-99
862962017392	PS00301 GTP-binding elongation factors signature.
862962017393	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017394	30S ribosomal protein S7; Validated; Region: PRK05302
862962017395	HMMPfam hit to PF00177, Ribosomal protein S7p/S5e, score 4e-68
862962017396	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017397	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
862962017398	S17 interaction site [polypeptide binding]; other site
862962017399	S8 interaction site; other site
862962017400	16S rRNA interaction site [nucleotide binding]; other site
862962017401	streptomycin interaction site [chemical binding]; other site
862962017402	23S rRNA interaction site [nucleotide binding]; other site
862962017403	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
862962017404	HMMPfam hit to PF00164, Ribosomal protein S12, score 2.1e-76
862962017405	PS00055 Ribosomal protein S12 signature.
862962017406	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
862962017407	1 probable transmembrane helix predicted for BF638R4047 by TMHMM2.0 at aa 4-26
862962017408	HMMPfam hit to PF04226, Transglycosylase associated protein, score 5.7e-05
862962017409	3 probable transmembrane helices predicted for BF638R4048 by TMHMM2.0 at aa 4-21, 28-50 and 55-77
862962017410	Acyltransferase family; Region: Acyl_transf_3; pfam01757
862962017411	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
862962017412	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
862962017413	HMMPfam hit to PF01757, Acyltransferase family, score 0.0024
862962017414	10 probable transmembrane helices predicted for BF638R4050 by TMHMM2.0 at aa 12-34, 49-71, 83-105, 142-164, 176-198, 218-235, 247-269, 279-301, 313-335 and 345-367
862962017415	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
862962017416	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
862962017417	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
862962017418	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
862962017419	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
862962017420	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
862962017421	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
862962017422	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
862962017423	DNA binding site [nucleotide binding]
862962017424	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
862962017425	HMMPfam hit to PF04998, RNA polymerase Rpb1, domain, score 1.6e-56
862962017426	HMMPfam hit to PF05000, RNA polymerase Rpb1, domain, score 8.6e-29
862962017427	HMMPfam hit to PF04983, RNA polymerase Rpb1, domain, score 1.8e-39
862962017428	HMMPfam hit to PF00623, RNA polymerase Rpb1, domain, score 4.7e-82
862962017429	HMMPfam hit to PF04997, RNA polymerase Rpb1, domain, score 7.9e-130
862962017430	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
862962017431	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
862962017432	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
862962017433	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
862962017434	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
862962017435	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
862962017436	RPB3 interaction site [polypeptide binding]; other site
862962017437	RPB1 interaction site [polypeptide binding]; other site
862962017438	RPB11 interaction site [polypeptide binding]; other site
862962017439	RPB10 interaction site [polypeptide binding]; other site
862962017440	HMMPfam hit to PF04560, RNA polymerase Rpb2, domain, score 6e-45
862962017441	HMMPfam hit to PF00562, RNA polymerase Rpb2, domain, score 2.1e-158
862962017442	PS01166 RNA polymerases beta chain signature.
862962017443	HMMPfam hit to PF04565, RNA polymerase Rpb2, domain, score 2.8e-40
862962017444	HMMPfam hit to PF04561, RNA polymerase Rpb2, domain, score 4.8e-20
862962017445	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
862962017446	core dimer interface [polypeptide binding]; other site
862962017447	peripheral dimer interface [polypeptide binding]; other site
862962017448	L10 interface [polypeptide binding]; other site
862962017449	L11 interface [polypeptide binding]; other site
862962017450	putative EF-Tu interaction site [polypeptide binding]; other site
862962017451	putative EF-G interaction site [polypeptide binding]; other site
862962017452	HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal dom, score 9.8e-33
862962017453	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
862962017454	23S rRNA interface [nucleotide binding]; other site
862962017455	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
862962017456	HMMPfam hit to PF00466, Ribosomal protein L10, score 6.1e-07
862962017457	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
862962017458	mRNA/rRNA interface [nucleotide binding]; other site
862962017459	HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family, score 3.3e-105
862962017460	PS01199 Ribosomal protein L1 signature.
862962017461	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
862962017462	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
862962017463	23S rRNA interface [nucleotide binding]; other site
862962017464	L7/L12 interface [polypeptide binding]; other site
862962017465	putative thiostrepton binding site; other site
862962017466	L25 interface [polypeptide binding]; other site
862962017467	PS00359 Ribosomal protein L11 signature.
862962017468	HMMPfam hit to PF00298, Ribosomal protein L11, RNA binding do, score 9.5e-33
862962017469	HMMPfam hit to PF03946, Ribosomal protein L11, N-terminal dom, score 1.3e-32
862962017470	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
862962017471	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
862962017472	putative homodimer interface [polypeptide binding]; other site
862962017473	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
862962017474	heterodimer interface [polypeptide binding]; other site
862962017475	homodimer interface [polypeptide binding]; other site
862962017476	HMMPfam hit to PF00467, KOW motif, score 3.9e-07
862962017477	HMMPfam hit to PF02357, Transcription termination factor nusG, score 7.4e-14
862962017478	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
862962017479	HMMPfam hit to PF00584, SecE/Sec61-gamma subunits of protein translo, score 1.1e-05
862962017480	1 probable transmembrane helix predicted for BF638R4058 by TMHMM2.0 at aa 54-76
862962017481	elongation factor Tu; Reviewed; Region: PRK12735
862962017482	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
862962017483	G1 box; other site
862962017484	GEF interaction site [polypeptide binding]; other site
862962017485	GTP/Mg2+ binding site [chemical binding]; other site
862962017486	Switch I region; other site
862962017487	G2 box; other site
862962017488	G3 box; other site
862962017489	Switch II region; other site
862962017490	G4 box; other site
862962017491	G5 box; other site
862962017492	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
862962017493	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
862962017494	Antibiotic Binding Site [chemical binding]; other site
862962017495	HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 2.4e-57
862962017496	HMMPfam hit to PF03144, Elongation factor Tu domain, score 4e-28
862962017497	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.3e-100
862962017498	PS00301 GTP-binding elongation factors signature.
862962017499	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017500	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
862962017501	30S subunit binding site; other site
862962017502	HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 1.5e-09
862962017503	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
862962017504	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
862962017505	active site
862962017506	Int/Topo IB signature motif; other site
862962017507	HMMPfam hit to PF00589, Phage integrase family, score 7.7e-31
862962017508	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 3.4e-23
862962017509	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
862962017510	HMMPfam hit to PF01165, Ribosomal protein S21, score 1.9e-08
862962017511	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
862962017512	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
862962017513	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
862962017514	active site
862962017515	HMMPfam hit to PF00557, metallopeptidase family M24, score 2.6e-10
862962017516	PS00141 Eukaryotic and viral aspartyl proteases active site.
862962017517	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
862962017518	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
862962017519	trimer interface [polypeptide binding]; other site
862962017520	putative metal binding site [ion binding]; other site
862962017521	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 8.7
862962017522	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 25
862962017523	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.64
862962017524	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.19
862962017525	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 12
862962017526	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
862962017527	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
862962017528	HMMPfam hit to PF04413, 3-Deoxy-D-manno-octulosonic-acid tran, score 7.6e-17
862962017529	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
862962017530	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
862962017531	HIGH motif; other site
862962017532	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
862962017533	active site
862962017534	KMSKS motif; other site
862962017535	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 1.3e-124
862962017536	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962017537	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
862962017538	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
862962017539	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
862962017540	Zn2+ binding site [ion binding]; other site
862962017541	Mg2+ binding site [ion binding]; other site
862962017542	7 probable transmembrane helices predicted for BF638R4068 by TMHMM2.0 at aa 15-34, 265-287, 302-324, 345-362, 366-385, 390-412 and 422-444
862962017543	HMMPfam hit to PF07698, 7TM receptor with intracellular HD hydrol, score 3.2e-49
862962017544	PS00287 Cysteine proteases inhibitors signature.
862962017545	HMMPfam hit to PF01966, HD domain, score 1.7e-18
862962017546	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
862962017547	Low molecular weight phosphatase family; Region: LMWPc; cd00115
862962017548	active site
862962017549	HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 2.7e-39
862962017550	Signal peptide predicted for BF638R4069 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.911 between residues 19 and 20
862962017551	Domain of unknown function (DUF4091); Region: DUF4091; pfam13320
862962017552	Signal peptide predicted for BF638R4070 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.987 between residues 34 and 35
862962017553	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
862962017554	primosomal protein N' Region: priA; TIGR00595
862962017555	ATP binding site [chemical binding]; other site
862962017556	putative Mg++ binding site [ion binding]; other site
862962017557	helicase superfamily c-terminal domain; Region: HELICc; smart00490
862962017558	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.9e-07
862962017559	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017560	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.5e-16
862962017561	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 5.3e-07
862962017562	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017563	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
862962017564	Signal peptide predicted for BF638R4072 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23
862962017565	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017566	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
862962017567	Aspartase; Region: Aspartase; cd01357
862962017568	active sites [active]
862962017569	tetramer interface [polypeptide binding]; other site
862962017570	HMMPfam hit to PF00206, Lyase, score 2.7e-135
862962017571	PS00163 Fumarate lyases signature.
862962017572	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
862962017573	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
862962017574	HMMPfam hit to PF03605, Anaerobic c4-dicarboxylate membrane transpo, score 2e-191
862962017575	10 probable transmembrane helices predicted for BF638R4076 by TMHMM2.0 at aa 30-52, 72-94, 115-137, 187-209, 250-272, 282-304, 316-338, 353-375, 382-404 and 439-458
862962017576	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017577	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
862962017578	active site
862962017579	homodimer interface [polypeptide binding]; other site
862962017580	homotetramer interface [polypeptide binding]; other site
862962017581	Signal peptide predicted for BF638R4077 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 23 and 24
862962017582	1 probable transmembrane helix predicted for BF638R4077 by TMHMM2.0 at aa 7-24
862962017583	PS00144 Asparaginase / glutaminase active site signature 1.
862962017584	HMMPfam hit to PF00710, Asparaginase, score 9e-144
862962017585	PS00917 Asparaginase / glutaminase active site signature 2.
862962017586	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
862962017587	Signal peptide predicted for BF638R4078 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 19 and 20
862962017588	Transposase; Region: DEDD_Tnp_IS110; pfam01548
862962017589	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
862962017590	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
862962017591	HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 3.8e-08
862962017592	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017593	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
862962017594	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017596	HMMPfam hit to PF02506, Type I restriction modification system, M, score 1e-09
862962017597	HMMPfam hit to PF02384, N-6 DNA Methylase, score 0.00027
862962017598	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
862962017599	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
862962017601	HMMPfam hit to PF00589, Phage integrase family, score 2.1e-08
862962017602	2 probable transmembrane helices predicted for BF638R4089 by TMHMM2.0 at aa 10-32 and 39-57
862962017603	DNA binding domain, excisionase family; Region: excise; TIGR01764
862962017604	AAA domain; Region: AAA_25; pfam13481
862962017605	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
862962017606	Walker A motif; other site
862962017607	ATP binding site [chemical binding]; other site
862962017608	Walker B motif; other site
862962017609	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017610	1 probable transmembrane helix predicted for BF638R4093 by TMHMM2.0 at aa 190-212
862962017611	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
862962017612	Trp docking motif [polypeptide binding]; other site
862962017613	active site
862962017614	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962017615	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962017616	dimer interface [polypeptide binding]; other site
862962017617	phosphorylation site [posttranslational modification]
862962017618	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962017619	ATP binding site [chemical binding]; other site
862962017620	Mg2+ binding site [ion binding]; other site
862962017621	G-X-G motif; other site
862962017622	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962017623	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962017624	active site
862962017625	phosphorylation site [posttranslational modification]
862962017626	intermolecular recognition site; other site
862962017627	dimerization interface [polypeptide binding]; other site
862962017628	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962017629	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962017630	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.2e-11
862962017631	PS00041 Bacterial regulatory proteins, araC family signature.
862962017632	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.026
862962017633	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.8e-24
862962017634	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.8e-30
862962017635	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.3e-07
862962017636	2 probable transmembrane helices predicted for BF638R4094 by TMHMM2.0 at aa 7-26 and 758-780
862962017637	HMMPfam hit to PF07495, Two component regulator three Y motif, score 0.00019
862962017638	HMMPfam hit to PF07494, Two component regulator propeller, score 0.0021
862962017639	HMMPfam hit to PF07494, Two component regulator propeller, score 1.3
862962017640	HMMPfam hit to PF07494, Two component regulator propeller, score 0.96
862962017641	HMMPfam hit to PF07494, Two component regulator propeller, score 0.45
862962017642	HMMPfam hit to PF07494, Two component regulator propeller, score 0.008
862962017643	Signal peptide predicted for BF638R4094 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.966 between residues 21 and 22
862962017644	transposase/IS protein; Provisional; Region: PRK09183
862962017645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962017646	Walker A motif; other site
862962017647	ATP binding site [chemical binding]; other site
862962017648	Walker B motif; other site
862962017649	HMMPfam hit to PF01695, IstB-like ATP binding protein, score 3.4e-71
862962017650	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
862962017651	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017653	HMMPfam hit to PF00665, Integrase core domain, score 1.8e-19
862962017654	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
862962017655	catalytic site [active]
862962017656	BNR repeat-like domain; Region: BNR_2; pfam13088
862962017657	Asp-box motif; other site
862962017658	Signal peptide predicted for BF638R4097 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 21 and 22
862962017659	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.4
862962017660	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.17
862962017661	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.25
862962017662	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 4
862962017663	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 11
862962017664	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
862962017665	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
862962017666	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
862962017667	HMMPfam hit to PF01609, Transposase DDE domain, score 6.6e-05
862962017668	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
862962017669	putative active cleft [active]
862962017670	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962017671	Major Facilitator Superfamily; Region: MFS_1; pfam07690
862962017672	putative substrate translocation pore; other site
862962017673	12 probable transmembrane helices predicted for BF638R4100 by TMHMM2.0 at aa 9-26, 52-74, 81-103, 107-129, 141-163, 167-189, 220-242, 262-284, 297-316, 320-337, 358-380 and 385-407
862962017674	HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00021
862962017675	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-46
862962017676	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017677	PS00217 Sugar transport proteins signature 2.
862962017678	cyclically-permuted mutarotase family protein; Region: mutarot_permut; TIGR03548
862962017679	Galactose oxidase, central domain; Region: Kelch_3; cl02701
862962017680	Signal peptide predicted for BF638R4101 by SignalP 2.0 HMM (Signal peptide probability 0.951) with cleavage site probability 0.462 between residues 28 and 29
862962017681	HMMPfam hit to PF01344, Kelch motif, score 0.42
862962017682	HMMPfam hit to PF01344, Kelch motif, score 0.09
862962017683	HMMPfam hit to PF01344, Kelch motif, score 3e-07; HMMPfam hit to PF07646, Kelch motif, score 6.9e-06
862962017684	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962017685	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962017686	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962017687	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962017688	Signal peptide predicted for BF638R4102 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.865 between residues 19 and 20
862962017689	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4e-15
862962017690	HMMPfam hit to PF00593, TonB dependent receptor, score 1.2e-13
862962017691	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962017692	SusD family; Region: SusD; pfam07980
862962017693	Signal peptide predicted for BF638R4103 by SignalP 2.0 HMM (Signal peptide probability 0.894) with cleavage site probability 0.484 between residues 23 and 24
862962017694	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017695	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
862962017696	active site
862962017697	catalytic residues [active]
862962017698	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017699	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 1.9e-12
862962017700	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
862962017701	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
862962017702	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
862962017703	active site
862962017704	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
862962017705	PA14 domain; Region: PA14; cl08459
862962017706	Signal peptide predicted for BF638R4105 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.403 between residues 24 and 25
862962017707	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017708	HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 0.057
862962017709	HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 5.8e-142
862962017710	HMMPfam hit to PF07691, PA14 domain, score 1.7e-06
862962017711	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
862962017712	active site
862962017713	catalytic residues [active]
862962017714	Signal peptide predicted for BF638R4106 by SignalP 2.0 HMM (Signal peptide probability 0.943) with cleavage site probability 0.554 between residues 19 and 20
862962017715	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 2.4e-05
862962017716	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
862962017717	Signal peptide predicted for BF638R4107 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 18 and 19
862962017718	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 3.6e-138
862962017719	PS01182 Glycosyl hydrolases family 35 putative active site.
862962017720	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962017721	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962017722	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962017723	Signal peptide predicted for BF638R4108 by SignalP 2.0 HMM (Signal peptide probability 0.849) with cleavage site probability 0.798 between residues 24 and 25
862962017724	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.5e-23
862962017725	HMMPfam hit to PF00593, TonB dependent receptor, score 4.6e-25
862962017726	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962017727	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962017728	SusD family; Region: SusD; pfam07980
862962017729	Signal peptide predicted for BF638R4109 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.430 between residues 19 and 20
862962017730	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017731	Signal peptide predicted for BF638R4111 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.557 between residues 50 and 51
862962017732	1 probable transmembrane helix predicted for BF638R4111 by TMHMM2.0 at aa 29-51
862962017733	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017734	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962017735	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
862962017736	Signal peptide predicted for BF638R4112 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.724 between residues 17 and 18
862962017737	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017738	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017739	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017741	Winged helix-turn helix; Region: HTH_29; pfam13551
862962017742	Helix-turn-helix domain; Region: HTH_28; pfam13518
862962017743	Domain of unknown function (DUF4373); Region: DUF4373; pfam14297
862962017744	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962017745	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
862962017746	Walker A motif; other site
862962017747	ATP binding site [chemical binding]; other site
862962017748	Walker B motif; other site
862962017749	HMMPfam hit to PF01695, IstB-like ATP binding protein, score 7.3e-50
862962017750	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017752	AAA domain; Region: AAA_14; pfam13173
862962017753	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
862962017754	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017755	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017756	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
862962017757	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
862962017758	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017759	Helix-turn-helix domain; Region: HTH_17; cl17695
862962017760	3 probable transmembrane helices predicted for BF638R4130 by TMHMM2.0 at aa 4-22, 29-51 and 61-83
862962017761	Signal peptide predicted for BF638R4130 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.518 between residues 26 and 27
862962017762	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962017763	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962017764	active site
862962017765	DNA binding site [nucleotide binding]
862962017766	Int/Topo IB signature motif; other site
862962017767	HMMPfam hit to PF00589, Phage integrase family, score 3e-15
862962017768	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
862962017769	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
862962017770	HMMPfam hit to PF01923, Cobalamin adenosyltransferase, score 5.3e-71
862962017771	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962017772	Signal peptide predicted for BF638R4135 by SignalP 2.0 HMM (Signal peptide probability 0.928) with cleavage site probability 0.786 between residues 19 and 20
862962017773	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017774	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962017775	Signal peptide predicted for BF638R4136 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.454 between residues 19 and 20
862962017776	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017777	Signal peptide predicted for BF638R4138 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 20 and 21
862962017778	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017779	Signal peptide predicted for BF638R4139 by SignalP 2.0 HMM (Signal peptide probability 0.942) with cleavage site probability 0.357 between residues 22 and 23
862962017780	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
862962017781	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962017782	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
862962017783	active site
862962017784	catalytic residues [active]
862962017785	DNA binding site [nucleotide binding]
862962017786	Int/Topo IB signature motif; other site
862962017787	HMMPfam hit to PF00589, Phage integrase family, score 3.7e-07
862962017788	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
862962017789	Signal peptide predicted for BF638R4141 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.618 between residues 39 and 40
862962017790	1 probable transmembrane helix predicted for BF638R4141 by TMHMM2.0 at aa 20-39
862962017791	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
862962017792	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 1.8e-34
862962017793	PS01182 Glycosyl hydrolases family 35 putative active site.
862962017794	Signal peptide predicted for BF638R4142 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.964 between residues 19 and 20
862962017795	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962017796	SusD family; Region: SusD; pfam07980
862962017797	Signal peptide predicted for BF638R4144 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.662 between residues 22 and 23
862962017798	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017799	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962017800	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962017801	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962017802	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962017803	HMMPfam hit to PF00593, TonB dependent receptor, score 2.1e-15
862962017804	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.5e-15
862962017805	1 probable transmembrane helix predicted for BF638R4145 by TMHMM2.0 at aa 20-39
862962017806	FecR protein; Region: FecR; pfam04773
862962017807	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962017808	HMMPfam hit to PF04773, FecR protein, score 1.8e-35
862962017809	1 probable transmembrane helix predicted for BF638R4146 by TMHMM2.0 at aa 76-98
862962017810	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962017811	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962017812	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962017813	DNA binding residues [nucleotide binding]
862962017814	HMMPfam hit to PF04545, Sigma-70, region, score 1.5e-11
862962017815	HMMPfam hit to PF04542, Sigma-70 region, score 4.5e-09
862962017816	Domain of unknonw function from B. Theta Gene description (DUF3874); Region: DUF3874; pfam12990
862962017817	sialate O-acetylesterase_like family of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like1; cd01827
862962017818	active site
862962017819	catalytic triad [active]
862962017820	oxyanion hole [active]
862962017821	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
862962017822	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962017823	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
862962017824	active site
862962017825	catalytic triad [active]
862962017826	oxyanion hole [active]
862962017827	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1.8e-11
862962017828	Signal peptide predicted for BF638R4150 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.980 between residues 20 and 21
862962017829	Transglutaminase/protease-like homologues; Region: TGc; smart00460
862962017830	Signal peptide predicted for BF638R4151 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.968 between residues 22 and 23
862962017831	1 probable transmembrane helix predicted for BF638R4152 by TMHMM2.0 at aa 7-29
862962017832	Signal peptide predicted for BF638R4152 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.582 between residues 24 and 25
862962017833	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962017834	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962017835	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962017836	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
862962017837	Signal peptide predicted for BF638R4153 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.456 between residues 24 and 25
862962017838	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017839	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
862962017840	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
862962017841	Interdomain contacts; other site
862962017842	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.023
862962017843	HMMPfam hit to PF00041, Fibronectin type III domain, score 1.5e-05
862962017844	Signal peptide predicted for BF638R4154 by SignalP 2.0 HMM (Signal peptide probability 0.766) with cleavage site probability 0.539 between residues 25 and 26
862962017845	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017846	Signal peptide predicted for BF638R4155 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.638 between residues 21 and 22
862962017847	Signal peptide predicted for BF638R4156 by SignalP 2.0 HMM (Signal peptide probability 0.974) with cleavage site probability 0.908 between residues 20 and 21
862962017848	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
862962017849	dimer interface [polypeptide binding]; other site
862962017850	ADP-ribose binding site [chemical binding]; other site
862962017851	active site
862962017852	nudix motif; other site
862962017853	metal binding site [ion binding]; metal-binding site
862962017854	HMMPfam hit to PF00293, NUDIX domain, score 1.4e-12
862962017855	Histidine kinase; Region: His_kinase; pfam06580
862962017856	4 probable transmembrane helices predicted for BF638R4159 by TMHMM2.0 at aa 22-44, 54-76, 96-118 and 122-144
862962017857	HMMPfam hit to PF06580, Histidine kinase, score 2.9e-27
862962017858	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962017859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962017860	active site
862962017861	phosphorylation site [posttranslational modification]
862962017862	intermolecular recognition site; other site
862962017863	dimerization interface [polypeptide binding]; other site
862962017864	LytTr DNA-binding domain; Region: LytTR; smart00850
862962017865	HMMPfam hit to PF00072, Response regulator receiver domain, score 2e-16
862962017866	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 7.4e-19
862962017867	4Fe-4S binding domain; Region: Fer4_5; pfam12801
862962017868	4Fe-4S binding domain; Region: Fer4_5; pfam12801
862962017869	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
862962017870	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
862962017871	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
862962017872	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
862962017873	Signal peptide predicted for BF638R4161 by SignalP 2.0 HMM (Signal peptide probability 0.957) with cleavage site probability 0.373 between residues 46 and 47
862962017874	4 probable transmembrane helices predicted for BF638R4161 by TMHMM2.0 at aa 7-29, 44-66, 103-125 and 166-188
862962017875	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 3.4e-05
862962017876	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00048
862962017877	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0072
862962017878	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.013
862962017879	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.0047
862962017880	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.3e-06
862962017881	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962017882	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
862962017883	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
862962017884	active site
862962017885	catalytic tetrad [active]
862962017886	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017887	HMMPfam hit to PF00248, Aldo/keto reductase family, score 2.5e-07
862962017888	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.015
862962017889	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
862962017890	Domain of unknown function (DUF1893); Region: TM1506; pfam08973
862962017891	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
862962017892	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
862962017893	N-terminal plug; other site
862962017894	ligand-binding site [chemical binding]; other site
862962017895	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.2e-18
862962017896	HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-27
862962017897	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
862962017898	5 probable transmembrane helices predicted for BF638R4164 by TMHMM2.0 at aa 20-39, 48-70, 85-107, 114-136 and 146-168
862962017899	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
862962017900	HMMPfam hit to PF07081, Protein of unknown function (DUF1349), score 1.6e-86
862962017901	Signal peptide predicted for BF638R4165 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.993 between residues 19 and 20
862962017902	maltose O-acetyltransferase; Provisional; Region: PRK10092
862962017903	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
862962017904	active site
862962017905	substrate binding site [chemical binding]; other site
862962017906	trimer interface [polypeptide binding]; other site
862962017907	CoA binding site [chemical binding]; other site
862962017908	PS00101 Hexapeptide-repeat containing-transferases signature.
862962017909	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.019
862962017910	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 16
862962017911	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 23
862962017912	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
862962017913	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
862962017914	DNA binding residues [nucleotide binding]
862962017915	dimerization interface [polypeptide binding]; other site
862962017916	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 1.3e-17
862962017917	PS00622 Bacterial regulatory proteins, luxR family signature.
862962017918	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
862962017919	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
862962017920	DNA binding site [nucleotide binding]
862962017921	active site
862962017922	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferas, score 4.3e-40
862962017923	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
862962017924	Cupin domain; Region: Cupin_2; pfam07883
862962017925	HMMPfam hit to PF07883, Cupin domain, score 5.5e-07
862962017926	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962017927	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962017928	PS00041 Bacterial regulatory proteins, araC family signature.
862962017929	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.6e-10
862962017930	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
862962017931	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
862962017932	TPP-binding site; other site
862962017933	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
862962017934	PYR/PP interface [polypeptide binding]; other site
862962017935	dimer interface [polypeptide binding]; other site
862962017936	TPP binding site [chemical binding]; other site
862962017937	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
862962017938	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 0.00012
862962017939	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.2e-14
862962017940	flavodoxin; Provisional; Region: PRK07116
862962017941	Signal peptide predicted for BF638R4172 by SignalP 2.0 HMM (Signal peptide probability 0.855) with cleavage site probability 0.807 between residues 21 and 22
862962017942	1 probable transmembrane helix predicted for BF638R4173 by TMHMM2.0 at aa 21-43
862962017943	Signal peptide predicted for BF638R4175 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.667 between residues 21 and 22
862962017944	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017945	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
862962017946	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
862962017947	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.5e-06
862962017948	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017951	ORF6N domain; Region: ORF6N; pfam10543
862962017952	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962017953	active site
862962017954	DNA binding site [nucleotide binding]
862962017955	Int/Topo IB signature motif; other site
862962017956	HMMPfam hit to PF00589, Phage integrase family, score 2.3e-06
862962017957	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
862962017958	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962017959	Phage associated DNA primase [General function prediction only]; Region: COG3378
862962017960	CHC2 zinc finger; Region: zf-CHC2; cl17510
862962017961	Toprim-like; Region: Toprim_2; pfam13155
862962017962	Transposase; Region: DEDD_Tnp_IS110; pfam01548
862962017963	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
862962017964	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
862962017965	HMMPfam hit to PF02371, Transposase IS116/IS110/IS902 family, score 6.5e-16
862962017966	PS00017 ATP/GTP-binding site motif A (P-loop).
862962017967	HMMPfam hit to PF01548, Transposase, score 0.00038
862962017968	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
862962017969	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
862962017970	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
862962017971	HMMPfam hit to PF01609, Transposase DDE domain, score 0.00021
862962017972	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962017973	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962017974	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962017975	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 9.7e-05
862962017976	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.5e-07
862962017977	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962017978	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962017979	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962017980	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962017981	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.6e-20
862962017982	HMMPfam hit to PF00593, TonB dependent receptor, score 3.8e-08
862962017983	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962017984	Signal peptide predicted for BF638R4194 by SignalP 2.0 HMM (Signal peptide probability 0.810) with cleavage site probability 0.481 between residues 28 and 29
862962017985	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962017986	Predicted permeases [General function prediction only]; Region: COG0701
862962017987	8 probable transmembrane helices predicted for BF638R4195 by TMHMM2.0 at aa 36-55, 75-97, 104-126, 131-153, 198-220, 235-257, 262-284 and 299-321
862962017988	HMMPfam hit to PF03773, Predicted permease, score 6.2e-62
862962017989	Low molecular weight phosphatase family; Region: LMWPc; cd00115
862962017990	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
862962017991	active site
862962017992	HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 3.2e-32
862962017993	6 probable transmembrane helices predicted for BF638R4197 by TMHMM2.0 at aa 15-37, 57-79, 94-113, 134-156, 171-193 and 214-236
862962017994	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembran, score 3.4e-05
862962017995	Glutaredoxin-like domain protein; Region: GlrX_arch; TIGR02187
862962017996	1 probable transmembrane helix predicted for BF638R4198 by TMHMM2.0 at aa 5-27
862962017997	Signal peptide predicted for BF638R4198 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.513 between residues 22 and 23
862962017998	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
862962017999	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
862962018000	dimerization interface [polypeptide binding]; other site
862962018001	putative DNA binding site [nucleotide binding]; other site
862962018002	putative Zn2+ binding site [ion binding]; other site
862962018003	HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 6.9e-13
862962018004	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
862962018005	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
862962018006	Substrate binding site; other site
862962018007	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.8e-50
862962018008	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
862962018009	nucleotide binding site/active site [active]
862962018010	HIT family signature motif; other site
862962018011	catalytic residue [active]
862962018012	HMMPfam hit to PF01230, HIT domain, score 1.1e-31
862962018013	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
862962018014	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
862962018015	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
862962018016	HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 2.3e-16
862962018017	HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 1.3e-28
862962018018	PS00829 Prokaryotic transcription elongation factors signature 1.
862962018019	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962018020	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962018021	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962018022	Signal peptide predicted for BF638R4205 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.645 between residues 46 and 47
862962018023	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018024	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
862962018025	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
862962018026	RNase E interface [polypeptide binding]; other site
862962018027	trimer interface [polypeptide binding]; other site
862962018028	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
862962018029	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
862962018030	RNase E interface [polypeptide binding]; other site
862962018031	trimer interface [polypeptide binding]; other site
862962018032	active site
862962018033	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
862962018034	putative nucleic acid binding region [nucleotide binding]; other site
862962018035	G-X-X-G motif; other site
862962018036	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
862962018037	RNA binding site [nucleotide binding]; other site
862962018038	domain interface; other site
862962018039	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 6.7e-30
862962018040	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 1.7e-13
862962018041	HMMPfam hit to PF03726, Polyribonucleotide nucleotidyltransferase,, score 2.1e-11
862962018042	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 1.9e-43
862962018043	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 7.8e-21
862962018044	HMMPfam hit to PF00013, KH domain, score 3.8e-15
862962018045	HMMPfam hit to PF00575, S1 RNA binding domain, score 1.2e-22
862962018046	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962018047	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962018048	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962018049	DNA binding residues [nucleotide binding]
862962018050	HMMPfam hit to PF04542, Sigma-70 region, score 1.8e-10
862962018051	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962018052	FecR protein; Region: FecR; pfam04773
862962018053	1 probable transmembrane helix predicted for BF638R4208 by TMHMM2.0 at aa 64-86
862962018054	HMMPfam hit to PF04773, FecR protein, score 2.2e-30
862962018055	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962018056	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018057	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018058	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018059	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
862962018060	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018061	Signal peptide predicted for BF638R4209 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.902 between residues 40 and 41
862962018062	HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 1.3e-08
862962018063	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.7e-19
862962018064	HMMPfam hit to PF00593, TonB dependent receptor, score 6.4e-24
862962018065	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
862962018066	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962018067	Signal peptide predicted for BF638R4210 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.651 between residues 23 and 24
862962018068	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018069	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
862962018070	Signal peptide predicted for BF638R4212 by SignalP 2.0 HMM (Signal peptide probability 0.660) with cleavage site probability 0.213 between residues 29 and 30
862962018071	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018072	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018073	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018074	The C-terminal domain of uncharacterized bacterial proteins; Region: Bvu_2165_C_like; cd12843
862962018075	butyrate kinase; Provisional; Region: PRK03011
862962018076	HMMPfam hit to PF00871, Acetokinase family, score 1.6e-60
862962018077	PS01076 Acetate and butyrate kinases family signature 2.
862962018078	PS01075 Acetate and butyrate kinases family signature 1.
862962018079	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
862962018080	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 2.5e-15
862962018081	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
862962018082	active site
862962018083	catalytic residues [active]
862962018084	Signal peptide predicted for BF638R4219 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.947 between residues 26 and 27
862962018085	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018086	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 6e-11
862962018087	PS00284 Serpins signature.
862962018088	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
862962018089	dimer interface [polypeptide binding]; other site
862962018090	catalytic triad [active]
862962018091	HMMPfam hit to PF02016, LD-carboxypeptidase, score 2.5e-17
862962018092	M28 Zn-Peptidases; Region: M28_like_6; cd08656
862962018093	Peptidase family M28; Region: Peptidase_M28; pfam04389
862962018094	metal binding site [ion binding]; metal-binding site
862962018095	Signal peptide predicted for BF638R4221 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.432 between residues 39 and 40
862962018096	1 probable transmembrane helix predicted for BF638R4221 by TMHMM2.0 at aa 21-40
862962018097	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018098	HMMPfam hit to PF04389, Peptidase family M28, score 6.3e-50
862962018099	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
862962018100	HMMPfam hit to PF02657, Fe-S metabolism associated domain, score 1e-42
862962018101	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962018102	non-specific DNA binding site [nucleotide binding]; other site
862962018103	salt bridge; other site
862962018104	sequence-specific DNA binding site [nucleotide binding]; other site
862962018105	HMMPfam hit to PF01381, Helix-turn-helix, score 3.1e-06
862962018106	4 probable transmembrane helices predicted for BF638R4224 by TMHMM2.0 at aa 7-24, 97-119, 140-159 and 179-201
862962018107	Signal peptide predicted for BF638R4224 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.453 between residues 24 and 25
862962018108	CAAX protease self-immunity; Region: Abi; pfam02517
862962018109	6 probable transmembrane helices predicted for BF638R4225 by TMHMM2.0 at aa 7-29, 44-63, 75-97, 166-188, 195-217 and 227-249
862962018110	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018111	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 8.9e-28
862962018112	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
862962018113	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
862962018114	active site
862962018115	Riboflavin kinase; Region: Flavokinase; pfam01687
862962018116	HMMPfam hit to PF01687, Riboflavin kinase / FAD synthetase, score 4.4e-44
862962018117	HMMPfam hit to PF06574, Riboflavin kinase (Flavokinase), score 1.2e-65
862962018118	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
862962018119	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
862962018120	motif II; other site
862962018121	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.5e-09
862962018122	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
862962018123	plasma-membrane calcium-translocating P-type ATPase; Region: ATPase-IIB_Ca; TIGR01517
862962018124	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
862962018125	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
862962018126	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
862962018127	motif II; other site
862962018128	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
862962018129	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 5.4e-06
862962018130	10 probable transmembrane helices predicted for BF638R4229 by TMHMM2.0 at aa 50-67, 71-93, 245-267, 287-309, 692-714, 724-746, 767-789, 799-821, 834-856 and 866-888
862962018131	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.1e-21
862962018132	PS00154 E1-E2 ATPases phosphorylation site.
862962018133	HMMPfam hit to PF00122, E1-E2 ATPase, score 1.5e-56
862962018134	HMMPfam hit to PF00690, Cation transporter/ATPase, N-terminus, score 2.4e-14
862962018135	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962018136	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962018137	dimer interface [polypeptide binding]; other site
862962018138	phosphorylation site [posttranslational modification]
862962018139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962018140	ATP binding site [chemical binding]; other site
862962018141	Mg2+ binding site [ion binding]; other site
862962018142	G-X-G motif; other site
862962018143	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962018144	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962018145	active site
862962018146	phosphorylation site [posttranslational modification]
862962018147	intermolecular recognition site; other site
862962018148	dimerization interface [polypeptide binding]; other site
862962018149	HMMPfam hit to PF00072, Response regulator receiver domain, score 5e-23
862962018150	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.5e-38
862962018151	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.6e-26
862962018152	HMMPfam hit to PF00301, Rubredoxin, score 1.9e-27
862962018153	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
862962018154	Rubredoxin; Region: Rubredoxin; pfam00301
862962018155	iron binding site [ion binding]; other site
862962018156	PS00202 Rubredoxin signature.
862962018157	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
862962018158	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
862962018159	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
862962018160	PhoU domain; Region: PhoU; pfam01895
862962018161	8 probable transmembrane helices predicted for BF638R4232 by TMHMM2.0 at aa 50-72, 87-109, 114-131, 141-158, 179-201, 205-227, 255-277 and 297-319
862962018162	HMMPfam hit to PF02690, Na+/Pi-cotransporter, score 2.7e-47
862962018163	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
862962018164	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
862962018165	active site
862962018166	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 3.2e-08
862962018167	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018168	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962018169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962018170	ATP binding site [chemical binding]; other site
862962018171	Mg2+ binding site [ion binding]; other site
862962018172	G-X-G motif; other site
862962018173	Signal peptide predicted for BF638R4235 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21
862962018174	1 probable transmembrane helix predicted for BF638R4235 by TMHMM2.0 at aa 263-285
862962018175	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 6.3e-23
862962018176	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
862962018177	putative catalytic site [active]
862962018178	putative metal binding site [ion binding]; other site
862962018179	putative phosphate binding site [ion binding]; other site
862962018180	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962018181	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
862962018182	active site
862962018183	metal binding site [ion binding]; metal-binding site
862962018184	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.8e-13
862962018185	PS00125 Serine/threonine specific protein phosphatases signature.
862962018186	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3.4e-21
862962018187	Signal peptide predicted for BF638R4236 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 19 and 20
862962018188	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
862962018189	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
862962018190	Domain of Unknown Function with PDB structure (DUF3858); Region: DUF3858; pfam12970
862962018191	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018192	Signal peptide predicted for BF638R4237 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.946 between residues 21 and 22
862962018193	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
862962018194	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
862962018195	Signal peptide predicted for BF638R4238 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.922 between residues 26 and 27
862962018196	2 probable transmembrane helices predicted for BF638R4239 by TMHMM2.0 at aa 21-43 and 48-70
862962018197	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018198	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
862962018199	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
862962018200	proline aminopeptidase P II; Provisional; Region: PRK10879
862962018201	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
862962018202	active site
862962018203	HMMPfam hit to PF00557, metallopeptidase family M24, score 1.1e-50
862962018204	1 probable transmembrane helix predicted for BF638R4241 by TMHMM2.0 at aa 48-65
862962018205	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
862962018206	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
862962018207	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
862962018208	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
862962018209	HMMPfam hit to PF04963, Sigma-54 factor, core binding domain, score 1.1e-28
862962018210	HMMPfam hit to PF04552, Sigma-54, DNA binding domain, score 1.4e-59
862962018211	PS00718 Sigma-54 factors family signature 2.
862962018212	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
862962018213	6 probable transmembrane helices predicted for BF638R4243 by TMHMM2.0 at aa 24-46, 56-78, 95-113, 118-140, 161-183 and 198-220
862962018214	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
862962018215	lipoyl attachment site [posttranslational modification]; other site
862962018216	HMMPfam hit to PF01597, Glycine cleavage H-protein, score 2.2e-56
862962018217	AIR carboxylase; Region: AIRC; pfam00731
862962018218	HMMPfam hit to PF00731, AIR carboxylase, score 2.2e-80
862962018219	2 probable transmembrane helices predicted for BF638R4245 by TMHMM2.0 at aa 79-101 and 116-138
862962018220	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
862962018221	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
862962018222	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
862962018223	HMMPfam hit to PF04551, GcpE protein, score 6.2e-40
862962018224	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
862962018225	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
862962018226	HMMPfam hit to PF02230, Phospholipase/Carboxylesterase, score 2e-06
862962018227	Signal peptide predicted for BF638R4247 by SignalP 2.0 HMM (Signal peptide probability 0.843) with cleavage site probability 0.547 between residues 20 and 21
862962018228	Glycosyl hydrolase family 43; Region: GH43_3; cd08982
862962018229	active site
862962018230	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
862962018231	sugar binding site [chemical binding]; other site
862962018232	HMMPfam hit to PF00041, Fibronectin type III domain, score 0.029
862962018233	HMMPfam hit to PF00754, F5/8 type C domain, score 2.3e-13
862962018234	HMMPfam hit to PF04616, Glycosyl hydrolases family, score 3.8e-11
862962018235	Signal peptide predicted for BF638R4248 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.971 between residues 19 and 20
862962018236	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
862962018237	Putative glucoamylase; Region: Glycoamylase; pfam10091
862962018238	Signal peptide predicted for BF638R4249 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.913 between residues 20 and 21
862962018239	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018240	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018241	starch binding outer membrane protein SusD; Region: SusD; cd08977
862962018242	Signal peptide predicted for BF638R4250 by SignalP 2.0 HMM (Signal peptide probability 0.698) with cleavage site probability 0.523 between residues 30 and 31
862962018243	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018244	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018245	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018246	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018247	HMMPfam hit to PF00593, TonB dependent receptor, score 5.7e-16
862962018248	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018249	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.5e-21
862962018250	Signal peptide predicted for BF638R4251 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.947 between residues 20 and 21
862962018251	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
862962018252	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
862962018253	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
862962018254	HMMPfam hit to PF01915, Glycosyl hydrolase family 3 C termina, score 6.7e-100
862962018255	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N termina, score 3.2e-121
862962018256	PS00775 Glycosyl hydrolases family 3 active site.
862962018257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018258	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962018259	Signal peptide predicted for BF638R4252 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.739 between residues 24 and 25
862962018260	Flagellar FliJ protein; Region: FliJ; pfam02050
862962018261	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
862962018262	1 probable transmembrane helix predicted for BF638R4253 by TMHMM2.0 at aa 743-765
862962018263	Signal peptide predicted for BF638R4253 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 20 and 21
862962018264	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018265	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
862962018266	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962018267	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
862962018268	protein binding site [polypeptide binding]; other site
862962018269	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
862962018270	Catalytic dyad [active]
862962018271	HMMPfam hit to PF03572, Peptidase family S41, score 1.8e-65
862962018272	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 3e-08
862962018273	Signal peptide predicted for BF638R4254 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.652 between residues 26 and 27
862962018274	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
862962018275	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
862962018276	substrate binding site [chemical binding]; other site
862962018277	ATP binding site [chemical binding]; other site
862962018278	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.6e-48
862962018279	PS00584 pfkB family of carbohydrate kinases signature 2.
862962018280	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
862962018282	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
862962018283	HMMPfam hit to PF07944, Protein of unknown function (DUF1680), score 9.1e-149
862962018284	Signal peptide predicted for BF638R4256 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.372 between residues 19 and 20
862962018285	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018286	1 probable transmembrane helix predicted for BF638R4257 by TMHMM2.0 at aa 7-26
862962018287	Signal peptide predicted for BF638R4257 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.951 between residues 24 and 25
862962018288	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018289	Signal peptide predicted for BF638R4258 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.551 between residues 22 and 23
862962018290	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018291	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962018292	SusD family; Region: SusD; pfam07980
862962018293	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018294	Signal peptide predicted for BF638R4259 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.783 between residues 16 and 17
862962018295	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018296	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018297	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018298	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018299	HMMPfam hit to PF00593, TonB dependent receptor, score 3.1e-09
862962018300	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-17
862962018301	1 probable transmembrane helix predicted for BF638R4260 by TMHMM2.0 at aa 19-36
862962018302	Signal peptide predicted for BF638R4260 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.905 between residues 35 and 36
862962018303	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962018304	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962018305	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962018306	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962018307	dimer interface [polypeptide binding]; other site
862962018308	phosphorylation site [posttranslational modification]
862962018309	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962018310	ATP binding site [chemical binding]; other site
862962018311	Mg2+ binding site [ion binding]; other site
862962018312	G-X-G motif; other site
862962018313	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962018314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962018315	active site
862962018316	phosphorylation site [posttranslational modification]
862962018317	intermolecular recognition site; other site
862962018318	dimerization interface [polypeptide binding]; other site
862962018319	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962018320	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962018321	Signal peptide predicted for BF638R4261 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.938 between residues 27 and 28
862962018322	2 probable transmembrane helices predicted for BF638R4261 by TMHMM2.0 at aa 12-29 and 780-802
862962018323	HMMPfam hit to PF07494, Two component regulator propeller, score 0.034
862962018324	HMMPfam hit to PF07494, Two component regulator propeller, score 0.16
862962018325	HMMPfam hit to PF07494, Two component regulator propeller, score 0.052
862962018326	HMMPfam hit to PF07494, Two component regulator propeller, score 3.4
862962018327	HMMPfam hit to PF07494, Two component regulator propeller, score 0.22
862962018328	HMMPfam hit to PF07494, Two component regulator propeller, score 0.12
862962018329	HMMPfam hit to PF07494, Two component regulator propeller, score 6.9
862962018330	HMMPfam hit to PF07494, Two component regulator propeller, score 0.074
862962018331	HMMPfam hit to PF07494, Two component regulator propeller, score 0.056
862962018332	HMMPfam hit to PF07495, Two component regulator three Y motif, score 0.00014
862962018333	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.6e-06
862962018334	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.9e-27
862962018335	PS00923 Aspartate and glutamate racemases signature 1.
862962018336	HMMPfam hit to PF00072, Response regulator receiver domain, score 1e-28
862962018337	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.004
862962018338	PS00041 Bacterial regulatory proteins, araC family signature.
862962018339	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6.8e-10
862962018340	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
862962018341	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962018342	FeS/SAM binding site; other site
862962018343	PS01087 Radical activating enzymes signature.
862962018344	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-21
862962018345	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
862962018346	HMMPfam hit to PF02901, Pyruvate formate lyase, score 3.9e-10
862962018347	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
862962018348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962018349	putative substrate translocation pore; other site
862962018350	Signal peptide predicted for BF638R4264 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.416 between residues 32 and 33
862962018351	12 probable transmembrane helices predicted for BF638R4264 by TMHMM2.0 at aa 7-29, 49-66, 78-97, 102-124, 136-158, 168-186, 243-265, 280-302, 309-326, 341-363, 376-398 and 403-420
862962018352	HMMPfam hit to PF00083, Sugar (and other) transporter, score 1.7e-118
862962018353	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.6e-30
862962018354	PS00216 Sugar transport proteins signature 1.
862962018355	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962018356	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
862962018357	active site
862962018358	catalytic residues [active]
862962018359	Signal peptide predicted for BF638R4265 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.849 between residues 25 and 26
862962018360	HMMPfam hit to PF01263, Aldose 1-epimerase, score 1.8e-115
862962018361	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
862962018362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
862962018363	Signal peptide predicted for BF638R4266 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.698 between residues 25 and 26
862962018364	HMMPfam hit to PF07944, Protein of unknown function (DUF1680), score 1.2e-201
862962018365	Uncharacterized conserved protein [Function unknown]; Region: COG1359
862962018366	HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 9.3e-20
862962018367	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
862962018368	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962018369	active site
862962018370	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018371	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
862962018372	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
862962018373	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
862962018374	active site
862962018375	dimerization interface [polypeptide binding]; other site
862962018376	HMMPfam hit to PF00459, Inositol monophosphatase family, score 6.5e-65
862962018377	PS00629 Inositol monophosphatase family signature 1.
862962018378	Signal peptide predicted for BF638R4270 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 20 and 21
862962018379	He_PIG associated, NEW1 domain of bacterial glycohydrolase; Region: He_PIG_assoc; pfam10632
862962018380	Putative Ig domain; Region: He_PIG; pfam05345
862962018381	alpha-galactosidase; Region: PLN02808; cl17638
862962018382	HMMPfam hit to PF02065, Melibiase, score 3.9e-09
862962018383	HMMPfam hit to PF05345, Putative Ig domain, score 9.6e-05
862962018384	Signal peptide predicted for BF638R4272 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 24 and 25
862962018385	Signal peptide predicted for BF638R4273 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.721 between residues 20 and 21
862962018386	Signal peptide predicted for BF638R4274 by SignalP 2.0 HMM (Signal peptide probability 0.759) with cleavage site probability 0.283 between residues 24 and 25
862962018387	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018388	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; cl17476
862962018390	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
862962018391	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
862962018392	active site
862962018393	metal-binding site
862962018394	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
862962018395	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
862962018396	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962018397	homodimer interface [polypeptide binding]; other site
862962018398	catalytic residue [active]
862962018399	HMMPfam hit to PF00155, Aminotransferase class I and II, score 6.4e-07
862962018400	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
862962018401	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
862962018402	pseudo-rSAM protein, GG-Bacteroidales system; Region: pseudo_rSAM_GG; TIGR04150
862962018403	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962018404	FeS/SAM binding site; other site
862962018405	radical SAM peptide maturase, GG-Bacteroidales family; Region: GG_samocin_CFB; TIGR04148
862962018406	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962018407	FeS/SAM binding site; other site
862962018408	HMMPfam hit to PF04055, Radical SAM superfamily, score 1.8e-08
862962018409	PS01305 moaA / nifB / pqqE family signature.
862962018410	Signal peptide predicted for BF638R4282 by SignalP 2.0 HMM (Signal peptide probability 0.949) with cleavage site probability 0.414 between residues 20 and 21
862962018411	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018412	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
862962018413	glycosyltransferase, GG-Bacteroidales peptide system; Region: glyco_rSAM_CFB; TIGR04157
862962018414	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962018415	HMMPfam hit to PF00534, Glycosyl transferases group, score 4.1e-19
862962018416	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962018417	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
862962018418	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
862962018419	Ligand binding site; other site
862962018420	metal-binding site
862962018421	HMMPfam hit to PF01501, Glycosyl transferase family, score 6.5e-54
862962018422	PS00107 Protein kinases ATP-binding region signature.
862962018423	Signal peptide predicted for BF638R4287 by SignalP 2.0 HMM (Signal peptide probability 0.621) with cleavage site probability 0.207 between residues 19 and 20
862962018424	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018426	Signal peptide predicted for BF638R4290 by SignalP 2.0 HMM (Signal peptide probability 0.839) with cleavage site probability 0.300 between residues 24 and 25
862962018427	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018428	Signal peptide predicted for BF638R4291 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.571 between residues 19 and 20
862962018429	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018430	Signal peptide predicted for BF638R4292 by SignalP 2.0 HMM (Signal peptide probability 0.924) with cleavage site probability 0.520 between residues 23 and 24
862962018431	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018432	LytTr DNA-binding domain; Region: LytTR; smart00850
862962018433	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 0.00012
862962018434	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018435	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
862962018436	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962018437	1 probable transmembrane helix predicted for BF638R4296 by TMHMM2.0 at aa 21-39
862962018438	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018439	Gram-negative bacterial tonB protein; Region: TonB; cl10048
862962018440	Signal peptide predicted for BF638R4297 by SignalP 2.0 HMM (Signal peptide probability 0.945) with cleavage site probability 0.398 between residues 25 and 26
862962018441	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
862962018442	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_22; cd04681
862962018443	nudix motif; other site
862962018444	HMMPfam hit to PF00293, NUDIX domain, score 9.4e-19
862962018445	PS00893 mutT domain signature.
862962018446	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
862962018447	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018448	binding surface
862962018449	TPR motif; other site
862962018450	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018451	binding surface
862962018452	TPR motif; other site
862962018453	Tetratricopeptide repeat; Region: TPR_12; pfam13424
862962018454	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018455	binding surface
862962018456	TPR motif; other site
862962018457	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
862962018458	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018459	binding surface
862962018460	TPR motif; other site
862962018461	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
862962018462	Signal peptide predicted for BF638R4300 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.915 between residues 22 and 23
862962018463	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.7
862962018464	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.1
862962018465	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.1; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.4
862962018466	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 2.3; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1
862962018467	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.068; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.081
862962018468	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.96; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.7
862962018469	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.1; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.6
862962018470	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.029; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.00021
862962018471	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2.1e-05; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00027
862962018472	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00028; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0006
862962018473	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0021; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.029
862962018474	HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00029; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 6.6e-05
862962018475	Signal peptide predicted for BF638R4301 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.973 between residues 22 and 23
862962018476	HMMPfam hit to PF00593, TonB dependent receptor, score 8.6e-07
862962018477	DNA topoisomerase I; Provisional; Region: PRK08780
862962018478	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
862962018479	active site
862962018480	interdomain interaction site; other site
862962018481	putative metal-binding site [ion binding]; other site
862962018482	nucleotide binding site [chemical binding]; other site
862962018483	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962018484	domain I; other site
862962018485	DNA binding groove [nucleotide binding]
862962018486	phosphate binding site [ion binding]; other site
862962018487	domain II; other site
862962018488	domain III; other site
862962018489	nucleotide binding site [chemical binding]; other site
862962018490	catalytic site [active]
862962018491	domain IV; other site
862962018492	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
862962018493	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
862962018494	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
862962018495	HMMPfam hit to PF01751, Toprim domain, score 3.1e-35
862962018496	HMMPfam hit to PF01131, DNA topoisomerase, score 1.4e-137
862962018497	PS00396 Prokaryotic DNA topoisomerase I active site.
862962018498	Signal peptide predicted for BF638R4303 by SignalP 2.0 HMM (Signal peptide probability 0.693) with cleavage site probability 0.563 between residues 19 and 20
862962018499	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018500	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
862962018501	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
862962018502	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962018503	active site
862962018504	HIGH motif; other site
862962018505	nucleotide binding site [chemical binding]; other site
862962018506	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
862962018507	KMSK motif region; other site
862962018508	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
862962018509	tRNA binding surface [nucleotide binding]; other site
862962018510	anticodon binding site; other site
862962018511	HMMPfam hit to PF05746, DALR anticodon binding domain, score 1e-41
862962018512	HMMPfam hit to PF00750, tRNA synthetases class I (R), score 1.4e-34
862962018513	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962018514	HMMPfam hit to PF03485, Arginyl tRNA synthetase N terminal do, score 0.0013
862962018515	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962018516	IHF dimer interface [polypeptide binding]; other site
862962018517	IHF - DNA interface [nucleotide binding]; other site
862962018518	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 8.3e-45
862962018519	PS00107 Protein kinases ATP-binding region signature.
862962018520	PS00045 Bacterial histone-like DNA-binding proteins signature.
862962018521	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
862962018522	Signal peptide predicted for BF638R4306 by SignalP 2.0 HMM (Signal peptide probability 0.725) with cleavage site probability 0.458 between residues 24 and 25
862962018523	6 probable transmembrane helices predicted for BF638R4306 by TMHMM2.0 at aa 7-29, 49-71, 84-106, 132-154, 161-183 and 193-212
862962018524	HMMPfam hit to PF01694, Rhomboid family, score 1.3e-34
862962018525	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
862962018526	5 probable transmembrane helices predicted for BF638R4307 by TMHMM2.0 at aa 21-43, 78-100, 107-129, 133-155 and 175-197
862962018527	HMMPfam hit to PF01694, Rhomboid family, score 8e-20
862962018528	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
862962018529	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
862962018530	putative catalytic site [active]
862962018531	putative metal binding site [ion binding]; other site
862962018532	putative phosphate binding site [ion binding]; other site
862962018533	Signal peptide predicted for BF638R4308 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.904 between residues 27 and 28
862962018534	3 probable transmembrane helices predicted for BF638R4308 by TMHMM2.0 at aa 7-29, 44-63 and 68-85
862962018535	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 5.1e-15
862962018536	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
862962018537	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
862962018538	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
862962018539	Protein export membrane protein; Region: SecD_SecF; pfam02355
862962018540	11 probable transmembrane helices predicted for BF638R4310 by TMHMM2.0 at aa 5-27, 509-531, 538-557, 561-580, 601-623, 633-655, 693-715, 830-849, 861-883, 937-959 and 966-988
862962018541	HMMPfam hit to PF07549, SecD/SecF GG Motif, score 0.00077
862962018542	HMMPfam hit to PF07549, SecD/SecF GG Motif, score 0.00017
862962018543	HMMPfam hit to PF02355, Protein export membrane protein, score 9.2e-63
862962018544	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962018545	IHF - DNA interface [nucleotide binding]; other site
862962018546	IHF dimer interface [polypeptide binding]; other site
862962018547	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 2.7e-26
862962018548	Signal peptide predicted for BF638R4312 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.744 between residues 27 and 28
862962018549	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
862962018550	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
862962018551	PS00044 Bacterial regulatory proteins, lysR family signature.
862962018552	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018553	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962018554	1 probable transmembrane helix predicted for BF638R4314 by TMHMM2.0 at aa 12-34
862962018555	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018556	Signal peptide predicted for BF638R4314 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.379 between residues 26 and 27
862962018557	Signal peptide predicted for BF638R4315 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.722 between residues 21 and 22
862962018558	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018559	1 probable transmembrane helix predicted for BF638R4316 by TMHMM2.0 at aa 12-34
862962018560	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018561	Signal peptide predicted for BF638R4316 by SignalP 2.0 HMM (Signal peptide probability 0.900) with cleavage site probability 0.247 between residues 31 and 32
862962018562	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962018563	Signal peptide predicted for BF638R4317 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.741 between residues 20 and 21
862962018564	Helix-turn-helix domain; Region: HTH_18; pfam12833
862962018565	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.14
862962018566	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.023
862962018567	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962018568	active site
862962018569	DNA binding site [nucleotide binding]
862962018570	Int/Topo IB signature motif; other site
862962018571	HMMPfam hit to PF00589, Phage integrase family, score 1.2e-06
862962018572	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 0.25
862962018573	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
862962018574	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
862962018575	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
862962018576	dimer interface [polypeptide binding]; other site
862962018577	PYR/PP interface [polypeptide binding]; other site
862962018578	TPP binding site [chemical binding]; other site
862962018579	substrate binding site [chemical binding]; other site
862962018580	HMMPfam hit to PF01855, Pyruvate flavodoxin/ferredoxin oxidoreductas, score 1.6e-51
862962018581	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867
862962018582	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
862962018583	TPP-binding site [chemical binding]; other site
862962018584	HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 2.5e-89
862962018585	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018586	5 probable transmembrane helices predicted for BF638R4323 by TMHMM2.0 at aa 7-29, 39-61, 68-90, 100-122 and 134-156
862962018587	Signal peptide predicted for BF638R4323 by SignalP 2.0 HMM (Signal peptide probability 0.948) with cleavage site probability 0.492 between residues 40 and 41
862962018588	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
862962018589	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
862962018590	putative active site [active]
862962018591	catalytic site [active]
862962018592	putative metal binding site [ion binding]; other site
862962018593	oligomer interface [polypeptide binding]; other site
862962018594	HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 2.1e-18
862962018595	Signal peptide predicted for BF638R4324 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.783 between residues 26 and 27
862962018596	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
862962018597	active site
862962018598	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 0.0031
862962018599	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
862962018600	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
862962018601	active site
862962018602	substrate-binding site [chemical binding]; other site
862962018603	metal-binding site [ion binding]
862962018604	ATP binding site [chemical binding]; other site
862962018605	HMMPfam hit to PF01293, Phosphoenolpyruvate carboxykinase, score 0
862962018606	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018607	1 probable transmembrane helix predicted for BF638R4327 by TMHMM2.0 at aa 13-35
862962018608	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018609	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018610	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018611	Signal peptide predicted for BF638R4328 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.545 between residues 40 and 41
862962018612	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.4e-22
862962018613	HMMPfam hit to PF00593, TonB dependent receptor, score 4.9e-12
862962018614	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018615	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962018616	SusD family; Region: SusD; pfam07980
862962018617	Signal peptide predicted for BF638R4329 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.650 between residues 25 and 26
862962018618	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018619	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018620	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018621	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018622	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962018623	Signal peptide predicted for BF638R4330 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.976 between residues 39 and 40
862962018624	1 probable transmembrane helix predicted for BF638R4330 by TMHMM2.0 at aa 17-39
862962018625	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.6e-20
862962018626	HMMPfam hit to PF00593, TonB dependent receptor, score 1.8e-16
862962018627	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018628	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962018629	SusD family; Region: SusD; pfam07980
862962018630	Signal peptide predicted for BF638R4331 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.596 between residues 28 and 29
862962018631	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018632	Signal peptide predicted for BF638R4332 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.767 between residues 28 and 29
862962018633	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018634	Right handed beta helix region; Region: Beta_helix; pfam13229
862962018635	Signal peptide predicted for BF638R4333 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.957 between residues 20 and 21
862962018636	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
862962018637	10 probable transmembrane helices predicted for BF638R4334 by TMHMM2.0 at aa 20-42, 62-80, 100-117, 122-141, 148-170, 208-230, 243-265, 270-292, 304-326 and 341-363
862962018638	Signal peptide predicted for BF638R4336 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.977 between residues 23 and 24
862962018639	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
862962018640	Signal peptide predicted for BF638R4337 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 22 and 23
862962018641	This hit extended beyond the end of the feature by 1 aa and was clipped.; PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site.
862962018642	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018643	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018644	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018645	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
862962018646	Signal peptide predicted for BF638R4338 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.545 between residues 40 and 41
862962018647	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 5.5e-21
862962018648	HMMPfam hit to PF00593, TonB dependent receptor, score 9.6e-13
862962018649	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018650	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962018651	SusD family; Region: SusD; pfam07980
862962018652	Signal peptide predicted for BF638R4339 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.511 between residues 21 and 22
862962018653	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018654	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
862962018655	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
862962018656	G1 box; other site
862962018657	putative GEF interaction site [polypeptide binding]; other site
862962018658	GTP/Mg2+ binding site [chemical binding]; other site
862962018659	Switch I region; other site
862962018660	G2 box; other site
862962018661	G3 box; other site
862962018662	Switch II region; other site
862962018663	G4 box; other site
862962018664	G5 box; other site
862962018665	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
862962018666	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
862962018667	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 2.6e-22
862962018668	HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.8e-14
862962018669	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 3.4e-62
862962018670	PS00301 GTP-binding elongation factors signature.
862962018671	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018672	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
862962018673	16S/18S rRNA binding site [nucleotide binding]; other site
862962018674	S13e-L30e interaction site [polypeptide binding]; other site
862962018675	25S rRNA binding site [nucleotide binding]; other site
862962018676	HMMPfam hit to PF00312, Ribosomal protein S15, score 3.4e-30
862962018677	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
862962018678	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
862962018679	non-specific DNA binding site [nucleotide binding]; other site
862962018680	salt bridge; other site
862962018681	sequence-specific DNA binding site [nucleotide binding]; other site
862962018682	Cupin domain; Region: Cupin_2; pfam07883
862962018683	HMMPfam hit to PF01381, Helix-turn-helix, score 5.9e-15
862962018684	HMMPfam hit to PF07883, Cupin domain, score 6.6e-12
862962018685	AMP-binding domain protein; Validated; Region: PRK08315
862962018686	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
862962018687	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
862962018688	acyl-activating enzyme (AAE) consensus motif; other site
862962018689	putative AMP binding site [chemical binding]; other site
862962018690	putative active site [active]
862962018691	putative CoA binding site [chemical binding]; other site
862962018692	HMMPfam hit to PF00501, AMP-binding enzyme, score 6.2e-127
862962018693	PS00455 Putative AMP-binding domain signature.
862962018694	PAS fold; Region: PAS_4; pfam08448
862962018695	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
862962018696	PAS fold; Region: PAS_4; pfam08448
862962018697	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962018698	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962018699	dimer interface [polypeptide binding]; other site
862962018700	phosphorylation site [posttranslational modification]
862962018701	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962018702	ATP binding site [chemical binding]; other site
862962018703	Mg2+ binding site [ion binding]; other site
862962018704	G-X-G motif; other site
862962018705	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.8e-38
862962018706	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.3e-21
862962018707	Adenosylhomocysteinase; Provisional; Region: PTZ00075
862962018708	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
862962018709	homotetramer interface [polypeptide binding]; other site
862962018710	ligand binding site [chemical binding]; other site
862962018711	catalytic site [active]
862962018712	NAD binding site [chemical binding]; other site
862962018713	HMMPfam hit to PF05221, S-adenosyl-L-homocysteine hydrolase, score 9.8e-159
862962018714	PS00738 S-adenosyl-L-homocysteine hydrolase signature 1.
862962018715	HMMPfam hit to PF00670, S-adenosyl-L-homocysteine hydrolase, NA, score 3.1e-116
862962018716	PS00739 S-adenosyl-L-homocysteine hydrolase signature 2.
862962018717	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
862962018718	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
862962018719	Signal peptide predicted for BF638R4346 by SignalP 2.0 HMM (Signal peptide probability 0.928) with cleavage site probability 0.909 between residues 27 and 28
862962018720	14 probable transmembrane helices predicted for BF638R4346 by TMHMM2.0 at aa 5-27, 90-112, 117-139, 144-163, 168-185, 189-206, 218-240, 332-354, 361-380, 395-417, 434-456, 496-513, 520-538 and 801-823
862962018721	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018722	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
862962018723	Sulfatase; Region: Sulfatase; pfam00884
862962018724	HMMPfam hit to PF00884, Sulfatase, score 2e-49
862962018725	PS00523 Sulfatases signature 1.
862962018726	Signal peptide predicted for BF638R4349 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.961 between residues 39 and 40
862962018728	Signal peptide predicted for BF638R4351 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.650 between residues 27 and 28
862962018729	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018730	Secretin and TonB N terminus short domain; Region: STN; pfam07660
862962018731	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018732	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018733	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962018734	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018735	HMMPfam hit to PF00593, TonB dependent receptor, score 3.1e-10
862962018736	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-18
862962018737	PS01307 Flagellar motor protein motA family signature.
862962018738	1 probable transmembrane helix predicted for BF638R4352 by TMHMM2.0 at aa 13-35
862962018739	Signal peptide predicted for BF638R4352 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.969 between residues 32 and 33
862962018740	FecR protein; Region: FecR; pfam04773
862962018741	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
862962018742	1 probable transmembrane helix predicted for BF638R4353 by TMHMM2.0 at aa 86-108
862962018743	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
862962018744	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962018745	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962018746	DNA binding residues [nucleotide binding]
862962018747	HMMPfam hit to PF04542, Sigma-70 region, score 2.9e-11
862962018748	HMMPfam hit to PF04545, Sigma-70, region, score 4.3e-13
862962018749	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
862962018750	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
862962018751	FtsX-like permease family; Region: FtsX; pfam02687
862962018752	HMMPfam hit to PF02687, Predicted permease, score 2.2e-34
862962018753	6 probable transmembrane helices predicted for BF638R4355 by TMHMM2.0 at aa 21-43, 142-164, 280-302, 325-347, 354-376 and 380-402
862962018754	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018755	Signal peptide predicted for BF638R4355 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.656 between residues 40 and 41
862962018756	Ribosome-binding factor A; Region: RBFA; pfam02033
862962018757	HMMPfam hit to PF02033, Ribosome-binding factor A, score 4.1e-12
862962018758	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
862962018759	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
862962018760	S-adenosylmethionine binding site [chemical binding]; other site
862962018761	HMMPfam hit to PF01596, O-methyltransferase, score 2.1e-46
862962018762	pyruvate kinase; Provisional; Region: PRK05826
862962018763	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
862962018764	domain interfaces; other site
862962018765	active site
862962018766	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 1.5e-06
862962018767	HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 3.4e-141
862962018768	PS00110 Pyruvate kinase active site signature.
862962018769	Dehydroquinase class II; Region: DHquinase_II; pfam01220
862962018770	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
862962018771	trimer interface [polypeptide binding]; other site
862962018772	active site
862962018773	dimer interface [polypeptide binding]; other site
862962018774	HMMPfam hit to PF01220, Dehydroquinase class II, score 9e-65
862962018775	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
862962018776	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
862962018777	active site
862962018778	Int/Topo IB signature motif; other site
862962018779	HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 6e-20
862962018780	HMMPfam hit to PF00589, Phage integrase family, score 6.7e-52
862962018781	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018782	TPR motif; other site
862962018783	binding surface
862962018784	Tetratricopeptide repeat; Region: TPR_16; pfam13432
862962018785	Signal peptide predicted for BF638R4362 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.714 between residues 25 and 26
862962018786	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018787	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.1
862962018788	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.6
862962018789	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
862962018790	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
862962018791	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
862962018792	catalytic residues [active]
862962018793	Signal peptide predicted for BF638R4363 by SignalP 2.0 HMM (Signal peptide probability 0.869) with cleavage site probability 0.306 between residues 16 and 17
862962018794	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
862962018795	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
862962018796	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
862962018797	Walker A motif; other site
862962018798	ATP binding site [chemical binding]; other site
862962018799	Walker B motif; other site
862962018800	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
862962018801	HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI, score 9.1e-66
862962018802	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018803	Signal peptide predicted for BF638R4365 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.304 between residues 24 and 25
862962018804	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018805	1 probable transmembrane helix predicted for BF638R4365 by TMHMM2.0 at aa 360-379
862962018806	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
862962018807	Signal peptide predicted for BF638R4366 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.577 between residues 20 and 21
862962018808	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
862962018809	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
862962018810	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
862962018811	Int/Topo IB signature motif; other site
862962018812	HMMPfam hit to PF00589, Phage integrase family, score 3e-10
862962018813	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962018814	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962018815	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
862962018816	HMMPfam hit to PF07693, KAP family P-loop domain, score 2.1e-08
862962018817	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018818	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
862962018819	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
862962018820	Signal peptide predicted for BF638R4375 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.572 between residues 32 and 33
862962018821	2 probable transmembrane helices predicted for BF638R4375 by TMHMM2.0 at aa 9-31 and 46-68
862962018822	Protein of unknown function (DUF1273); Region: DUF1273; cl01859
862962018823	1 probable transmembrane helix predicted for BF638R4377 by TMHMM2.0 at aa 145-164
862962018824	ParB-like nuclease domain; Region: ParB; smart00470
862962018825	PRTRC system ParB family protein; Region: PRTRC_parB; TIGR03734
862962018826	HMMPfam hit to PF02195, ParB-like nuclease domain, score 8.1e-33
862962018827	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
862962018828	MPN+ (JAMM) motif; other site
862962018829	Zinc-binding site [ion binding]; other site
862962018830	HMMPfam hit to PF04002, RadC, DNA repair protein, score 1.6e-17
862962018831	PS01302 DNA repair protein radC family signature.
862962018832	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
862962018833	PS00687 Aldehyde dehydrogenases glutamic acid active site.
862962018834	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
862962018835	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018836	Signal peptide predicted for BF638R4384 by SignalP 2.0 HMM (Signal peptide probability 0.758) with cleavage site probability 0.508 between residues 25 and 26
862962018837	Conjugative transposon protein TraO; Region: TraO; pfam10626
862962018838	Signal peptide predicted for BF638R4385 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.959 between residues 22 and 23
862962018839	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
862962018840	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
862962018841	Signal peptide predicted for BF638R4386 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.943 between residues 20 and 21
862962018842	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
862962018843	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
862962018844	1 probable transmembrane helix predicted for BF638R4387 by TMHMM2.0 at aa 58-77
862962018845	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
862962018846	1 probable transmembrane helix predicted for BF638R4389 by TMHMM2.0 at aa 31-53
862962018847	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
862962018848	Signal peptide predicted for BF638R4390 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.508 between residues 42 and 43
862962018849	1 probable transmembrane helix predicted for BF638R4390 by TMHMM2.0 at aa 13-35
862962018850	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
862962018851	HMMPfam hit to PF07863, Homologues of TraJ from Bacteroides conju, score 1.1e-20
862962018852	5 probable transmembrane helices predicted for BF638R4391 by TMHMM2.0 at aa 30-52, 67-89, 193-212, 222-244 and 272-294
862962018853	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
862962018854	Signal peptide predicted for BF638R4392 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.979 between residues 21 and 22
862962018855	Domain of unknown function, B. Theta Gene description (DUF3876); Region: DUF3876; pfam12992
862962018856	1 probable transmembrane helix predicted for BF638R4393 by TMHMM2.0 at aa 4-23
862962018857	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018858	Signal peptide predicted for BF638R4393 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.551 between residues 18 and 19
862962018859	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
862962018860	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
862962018861	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018862	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
862962018863	2 probable transmembrane helices predicted for BF638R4395 by TMHMM2.0 at aa 21-43 and 48-70
862962018864	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
862962018865	3 probable transmembrane helices predicted for BF638R4396 by TMHMM2.0 at aa 7-29, 44-63 and 76-98
862962018866	Signal peptide predicted for BF638R4396 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.937 between residues 21 and 22
862962018867	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
862962018868	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
862962018869	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
862962018870	P-loop; other site
862962018871	Magnesium ion binding site [ion binding]; other site
862962018872	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
862962018873	YWFCY protein; Region: YWFCY; pfam14293
862962018874	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
862962018875	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
862962018876	5 probable transmembrane helices predicted for BF638R4404 by TMHMM2.0 at aa 54-76, 96-118, 130-152, 162-181 and 351-370
862962018877	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018878	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018879	Signal peptide predicted for BF638R4406 by SignalP 2.0 HMM (Signal peptide probability 0.679) with cleavage site probability 0.461 between residues 22 and 23
862962018880	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018881	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018882	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018883	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
862962018884	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962018885	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962018886	ligand binding site [chemical binding]; other site
862962018887	HMMPfam hit to PF00691, OmpA family, score 3.2e-20
862962018888	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
862962018889	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
862962018890	ligand binding site [chemical binding]; other site
862962018891	Signal peptide predicted for BF638R4408 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.659 between residues 23 and 24
862962018892	HMMPfam hit to PF00691, OmpA family, score 4e-06
862962018893	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cl00200
862962018894	amphipathic channel; other site
862962018895	Asn-Pro-Ala signature motifs; other site
862962018896	HMMPfam hit to PF00230, Major intrinsic protein, score 9.8e-44
862962018897	Signal peptide predicted for BF638R4409 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.969 between residues 25 and 26
862962018898	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018899	6 probable transmembrane helices predicted for BF638R4409 by TMHMM2.0 at aa 13-35, 40-62, 83-105, 125-147, 160-182 and 197-219
862962018900	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018901	PS00221 MIP family signature.
862962018902	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
862962018903	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
862962018904	HMMPfam hit to PF01741, Large-conductance mechanosensitive channel,, score 1.8e-64
862962018905	PS01327 Large-conductance mechanosensitive channels mscL family signature.
862962018906	2 probable transmembrane helices predicted for BF638R4410 by TMHMM2.0 at aa 23-45 and 85-107
862962018907	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
862962018908	IHF dimer interface [polypeptide binding]; other site
862962018909	IHF - DNA interface [nucleotide binding]; other site
862962018910	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 2.1e-21
862962018911	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
862962018912	Signal peptide predicted for BF638R4412 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.554 between residues 22 and 23
862962018913	Clostripain family; Region: Peptidase_C11; pfam03415
862962018914	Signal peptide predicted for BF638R4415 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.513 between residues 41 and 42
862962018915	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018916	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
862962018917	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
862962018918	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018919	DNA topoisomerase III; Provisional; Region: PRK07726
862962018920	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
862962018921	active site
862962018922	putative interdomain interaction site [polypeptide binding]; other site
862962018923	putative metal-binding site [ion binding]; other site
862962018924	putative nucleotide binding site [chemical binding]; other site
862962018925	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
862962018926	domain I; other site
862962018927	DNA binding groove [nucleotide binding]
862962018928	phosphate binding site [ion binding]; other site
862962018929	domain II; other site
862962018930	domain III; other site
862962018931	nucleotide binding site [chemical binding]; other site
862962018932	catalytic site [active]
862962018933	domain IV; other site
862962018934	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
862962018935	HMMPfam hit to PF01751, Toprim domain, score 5.8e-15
862962018936	HMMPfam hit to PF01131, DNA topoisomerase, score 2.2e-81
862962018937	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
862962018938	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
862962018939	HMMPfam hit to PF06250, Protein of unknown function (DUF1016), score 5.6e-54
862962018940	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962018941	RibD C-terminal domain; Region: RibD_C; cl17279
862962018942	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962018943	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
862962018944	active site
862962018945	metal binding site [ion binding]; metal-binding site
862962018946	interdomain interaction site; other site
862962018947	AAA domain; Region: AAA_25; pfam13481
862962018948	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018949	Helix-turn-helix domain; Region: HTH_17; pfam12728
862962018950	RteC protein; Region: RteC; pfam09357
862962018951	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
862962018952	PS00018 EF-hand calcium-binding domain.
862962018953	Signal peptide predicted for BF638R4424 by SignalP 2.0 HMM (Signal peptide probability 0.709) with cleavage site probability 0.674 between residues 23 and 24
862962018954	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018955	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
862962018956	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018957	Signal peptide predicted for BF638R4427 by SignalP 2.0 HMM (Signal peptide probability 0.905) with cleavage site probability 0.886 between residues 21 and 22
862962018958	PS00017 ATP/GTP-binding site motif A (P-loop).
862962018959	Signal peptide predicted for BF638R4428 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.811 between residues 20 and 21
862962018960	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962018961	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
862962018962	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
862962018963	ligand binding site [chemical binding]; other site
862962018964	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
862962018965	binding surface
862962018966	TPR motif; other site
862962018967	Signal peptide predicted for BF638R4429 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 26 and 27
862962018968	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962018969	Signal peptide predicted for BF638R4430 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.941 between residues 23 and 24
862962018970	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962018971	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962018972	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00067
862962018973	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.5e-06
862962018974	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
862962018975	active site
862962018976	DNA binding site [nucleotide binding]
862962018977	Int/Topo IB signature motif; other site
862962018978	HMMPfam hit to PF00589, Phage integrase family, score 1.4e-06
862962018979	Signal peptide predicted for BF638R4436 by SignalP 2.0 HMM (Signal peptide probability 0.926) with cleavage site probability 0.751 between residues 26 and 27
862962018980	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
862962018981	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018982	HMMPfam hit to PF00593, TonB dependent receptor, score 1.5e-11
862962018983	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.8e-10
862962018984	1 probable transmembrane helix predicted for BF638R4438 by TMHMM2.0 at aa 45-67
862962018985	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
862962018986	ParB-like nuclease domain; Region: ParBc; pfam02195
862962018987	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
862962018988	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
862962018989	Active Sites [active]
862962018990	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
862962018991	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
862962018992	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962018993	SusD family; Region: SusD; pfam07980
862962018994	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962018995	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962018996	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962018997	HMMPfam hit to PF00593, TonB dependent receptor, score 4.6e-25
862962018998	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 9.5e-23
862962018999	Signal peptide predicted for BF638R4443 by SignalP 2.0 HMM (Signal peptide probability 0.892) with cleavage site probability 0.799 between residues 24 and 25
862962019000	Uncharacterized protein conserved in Bacteroidetes; Region: DUF4425; cd11379
862962019001	dimer interface [polypeptide binding]; other site
862962019002	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019003	1 probable transmembrane helix predicted for BF638R4444 by TMHMM2.0 at aa 7-29
862962019004	Signal peptide predicted for BF638R4445 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 21 and 22
862962019005	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
862962019006	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
862962019007	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962019008	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962019009	dimer interface [polypeptide binding]; other site
862962019010	phosphorylation site [posttranslational modification]
862962019011	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962019012	ATP binding site [chemical binding]; other site
862962019013	Mg2+ binding site [ion binding]; other site
862962019014	G-X-G motif; other site
862962019015	Response regulator receiver domain; Region: Response_reg; pfam00072
862962019016	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962019017	active site
862962019018	phosphorylation site [posttranslational modification]
862962019019	intermolecular recognition site; other site
862962019020	dimerization interface [polypeptide binding]; other site
862962019021	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
862962019022	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962019023	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2.5e-10
862962019024	PS00041 Bacterial regulatory proteins, araC family signature.
862962019025	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 0.0015
862962019026	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.6e-31
862962019027	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.1e-20
862962019028	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-15
862962019029	2 probable transmembrane helices predicted for BF638R4446 by TMHMM2.0 at aa 5-22 and 782-804
862962019030	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
862962019031	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019032	HMMPfam hit to PF07495, Two component regulator three Y motif, score 4e-10
862962019033	HMMPfam hit to PF07494, Two component regulator propeller, score 0.68
862962019034	HMMPfam hit to PF07494, Two component regulator propeller, score 13
862962019035	HMMPfam hit to PF07494, Two component regulator propeller, score 0.021
862962019036	HMMPfam hit to PF07494, Two component regulator propeller, score 0.11
862962019037	HMMPfam hit to PF07494, Two component regulator propeller, score 1.5
862962019038	HMMPfam hit to PF07494, Two component regulator propeller, score 0.02
862962019039	HMMPfam hit to PF07494, Two component regulator propeller, score 0.54
862962019040	HMMPfam hit to PF07494, Two component regulator propeller, score 13
862962019041	HMMPfam hit to PF07494, Two component regulator propeller, score 12
862962019042	HMMPfam hit to PF07494, Two component regulator propeller, score 4.6
862962019043	HMMPfam hit to PF07494, Two component regulator propeller, score 9.7
862962019044	HMMPfam hit to PF07494, Two component regulator propeller, score 0.062
862962019045	HMMPfam hit to PF07494, Two component regulator propeller, score 0.029
862962019046	Signal peptide predicted for BF638R4446 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.667 between residues 19 and 20
862962019047	radical SAM enzyme, rSAM/lipoprotein system; Region: rSAM_w_lipo; TIGR04133
862962019048	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
862962019049	FeS/SAM binding site; other site
862962019050	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
862962019051	HMMPfam hit to PF04055, Radical SAM superfamily, score 4e-24
862962019052	putative lipoprotein, rSAM/lipoprotein system; Region: lipo_with_rSAM; TIGR04134
862962019053	Signal peptide predicted for BF638R4448 by SignalP 2.0 HMM (Signal peptide probability 0.899) with cleavage site probability 0.389 between residues 31 and 32
862962019054	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019055	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
862962019056	CoA binding domain; Region: CoA_binding_2; pfam13380
862962019057	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
862962019058	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
862962019059	HMMPfam hit to PF02629, CoA binding domain, score 5.8e-10
862962019060	Signal peptide predicted for BF638R4450 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.541 between residues 28 and 29
862962019061	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
862962019062	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019063	1 probable transmembrane helix predicted for BF638R4453 by TMHMM2.0 at aa 7-29
862962019064	NVEALA protein; Region: NVEALA; pfam14055
862962019065	Signal peptide predicted for BF638R4454 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.937 between residues 33 and 34
862962019066	1 probable transmembrane helix predicted for BF638R4454 by TMHMM2.0 at aa 13-32
862962019067	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019068	Signal peptide predicted for BF638R4455 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.417 between residues 22 and 23
862962019069	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
862962019070	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
862962019071	active site
862962019072	HIGH motif; other site
862962019073	KMSKS motif; other site
862962019074	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
862962019075	tRNA binding surface [nucleotide binding]; other site
862962019076	anticodon binding site; other site
862962019077	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
862962019078	dimer interface [polypeptide binding]; other site
862962019079	putative tRNA-binding site [nucleotide binding]; other site
862962019080	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 1.9e-08
862962019081	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962019082	HMMPfam hit to PF01588, Putative tRNA binding domain, score 3.9e-43
862962019083	colanic acid exporter; Provisional; Region: PRK10459
862962019084	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
862962019085	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 4.8e-19
862962019086	11 probable transmembrane helices predicted for BF638R4457 by TMHMM2.0 at aa 39-61, 71-90, 110-132, 142-164, 177-199, 204-221, 320-342, 352-374, 405-427, 442-461 and 466-488
862962019087	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019088	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962019089	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962019090	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.1e-30
862962019091	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962019092	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
862962019093	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962019094	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
862962019095	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.7e-38
862962019096	1 probable transmembrane helix predicted for BF638R4461 by TMHMM2.0 at aa 4-26
862962019097	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
862962019098	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
862962019099	active site
862962019100	homodimer interface [polypeptide binding]; other site
862962019101	HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 2.2e-168
862962019102	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
862962019103	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
862962019104	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
862962019105	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
862962019106	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 1.1e-14
862962019107	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 4.8e-36
862962019108	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 1.8e-68
862962019109	Signal peptide predicted for BF638R4463 by SignalP 2.0 HMM (Signal peptide probability 0.861) with cleavage site probability 0.291 between residues 18 and 19
862962019110	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
862962019111	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
862962019112	HMMPfam hit to PF00534, Glycosyl transferases group, score 4.1e-31
862962019113	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
862962019114	metal-binding site
862962019115	HMMPfam hit to PF00535, Glycosyl transferase, score 9e-30
862962019116	NAD-dependent deacetylase; Provisional; Region: PRK00481
862962019117	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
862962019118	NAD+ binding site [chemical binding]; other site
862962019119	substrate binding site [chemical binding]; other site
862962019120	Zn binding site [ion binding]; other site
862962019121	HMMPfam hit to PF02146, Sir2 family, score 3.9e-58
862962019122	Signal peptide predicted for BF638R4466 by SignalP 2.0 HMM (Signal peptide probability 0.675) with cleavage site probability 0.261 between residues 27 and 28
862962019123	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
862962019124	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
862962019125	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
862962019126	HMMPfam hit to PF01346, Domain amino terminal to FKBP-type peptidyl-, score 1.8e-08
862962019127	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 1.8e-46
862962019128	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
862962019129	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
862962019130	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
862962019131	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
862962019132	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
862962019133	Signal peptide predicted for BF638R4468 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.630 between residues 23 and 24
862962019134	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019135	HMMPfam hit to PF01346, Domain amino terminal to FKBP-type peptidyl-, score 1e-05
862962019136	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 7.4e-39
862962019137	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
862962019138	PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2.
862962019139	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
862962019140	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
862962019141	putative DNA binding site [nucleotide binding]; other site
862962019142	putative Zn2+ binding site [ion binding]; other site
862962019143	AsnC family; Region: AsnC_trans_reg; pfam01037
862962019144	HMMPfam hit to PF01037, AsnC family, score 1.2e-20
862962019145	3 probable transmembrane helices predicted for BF638R4470 by TMHMM2.0 at aa 7-29, 34-56 and 61-78
862962019146	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
862962019147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962019148	active site
862962019149	phosphorylation site [posttranslational modification]
862962019150	intermolecular recognition site; other site
862962019151	dimerization interface [polypeptide binding]; other site
862962019152	LytTr DNA-binding domain; Region: LytTR; smart00850
862962019153	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 5.8e-18
862962019154	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.8e-09
862962019155	Histidine kinase; Region: His_kinase; pfam06580
862962019156	HMMPfam hit to PF06580, Histidine kinase, score 5.6e-34
862962019157	4 probable transmembrane helices predicted for BF638R4472 by TMHMM2.0 at aa 7-26, 36-58, 78-100 and 115-137
862962019158	Outer membrane efflux protein; Region: OEP; pfam02321
862962019159	Outer membrane efflux protein; Region: OEP; pfam02321
862962019160	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.2e-12
862962019161	HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.6e-22
862962019162	Signal peptide predicted for BF638R4473 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 22 and 23
862962019163	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
862962019164	HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 4.8e-71
862962019165	12 probable transmembrane helices predicted for BF638R4474 by TMHMM2.0 at aa 13-30, 334-356, 361-383, 387-406, 427-449, 464-486, 518-540, 851-873, 880-899, 904-926, 955-977 and 982-1004
862962019166	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019167	Signal peptide predicted for BF638R4474 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.732 between residues 23 and 24
862962019168	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
862962019169	HlyD family secretion protein; Region: HlyD_3; pfam13437
862962019170	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019171	Signal peptide predicted for BF638R4475 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.342 between residues 15 and 16
862962019172	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
862962019173	Signal peptide predicted for BF638R4476 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.526 between residues 38 and 39
862962019174	1 probable transmembrane helix predicted for BF638R4476 by TMHMM2.0 at aa 13-35
862962019175	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019176	HMMPfam hit to PF01427, D-ala-D-ala dipeptidase, score 2e-21
862962019177	Methyltransferase domain; Region: Methyltransf_18; pfam12847
862962019178	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019179	Signal peptide predicted for BF638R4478 by SignalP 2.0 HMM (Signal peptide probability 0.851) with cleavage site probability 0.732 between residues 19 and 20
862962019180	starch binding outer membrane protein SusD; Region: SusD; cl17845
862962019181	SusD family; Region: SusD; pfam07980
862962019182	Signal peptide predicted for BF638R4479 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.601 between residues 23 and 24
862962019183	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019184	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
862962019185	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962019186	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
862962019187	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
862962019188	HMMPfam hit to PF00593, TonB dependent receptor, score 5e-19
862962019189	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-21
862962019190	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
862962019191	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
862962019192	Signal peptide predicted for BF638R4481 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.582 between residues 32 and 33
862962019193	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
862962019194	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962019195	putative substrate translocation pore; other site
862962019196	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
862962019197	HMMPfam hit to PF00083, Sugar (and other) transporter, score 2.4e-130
862962019198	12 probable transmembrane helices predicted for BF638R4482 by TMHMM2.0 at aa 7-29, 44-66, 79-98, 102-124, 136-158, 163-185, 242-264, 279-301, 308-330, 340-362, 374-396 and 401-423
862962019199	HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-42
862962019200	PS00216 Sugar transport proteins signature 1.
862962019201	PS00217 Sugar transport proteins signature 2.
862962019202	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019203	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019204	Signal peptide predicted for BF638R4482 by SignalP 2.0 HMM (Signal peptide probability 0.790) with cleavage site probability 0.686 between residues 32 and 33
862962019205	Signal peptide predicted for BF638R4483 by SignalP 2.0 HMM (Signal peptide probability 0.875) with cleavage site probability 0.395 between residues 31 and 32
862962019206	1 probable transmembrane helix predicted for BF638R4483 by TMHMM2.0 at aa 7-29
862962019207	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019208	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019209	The C-terminal domain of uncharacterized bacterial proteins; Region: Bvu_2165_C_like; cd12843
862962019210	Periplasmic binding domain of two-component sensor kinase signaling systems; Region: PBP1_sensor_kinase_like; cd06308
862962019211	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
862962019212	putative ligand binding site [chemical binding]; other site
862962019213	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
862962019214	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
862962019215	dimer interface [polypeptide binding]; other site
862962019216	phosphorylation site [posttranslational modification]
862962019217	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962019218	ATP binding site [chemical binding]; other site
862962019219	Mg2+ binding site [ion binding]; other site
862962019220	G-X-G motif; other site
862962019221	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
862962019222	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
862962019223	active site
862962019224	phosphorylation site [posttranslational modification]
862962019225	intermolecular recognition site; other site
862962019226	dimerization interface [polypeptide binding]; other site
862962019227	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962019228	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962019229	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962019230	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.5e-09
862962019231	PS00041 Bacterial regulatory proteins, araC family signature.
862962019232	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 5.2e-07
862962019233	HMMPfam hit to PF00072, Response regulator receiver domain, score 1e-29
862962019234	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.8e-35
862962019235	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.7e-15
862962019236	1 probable transmembrane helix predicted for BF638R4486 by TMHMM2.0 at aa 347-366
862962019237	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.0045
862962019238	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019239	Signal peptide predicted for BF638R4486 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.714 between residues 23 and 24
862962019240	Glycosyl hydrolases family 32 N-terminal domain; Region: Glyco_hydro_32N; pfam00251
862962019241	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
862962019242	substrate binding [chemical binding]; other site
862962019243	active site
862962019244	HMMPfam hit to PF00251, Glycosyl hydrolases family, score 8e-75
862962019245	Signal peptide predicted for BF638R4487 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.977 between residues 23 and 24
862962019246	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
862962019247	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
862962019248	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962019249	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962019250	Signal peptide predicted for BF638R4488 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 23 and 24
862962019251	HMMPfam hit to PF05738, no description, score 0.0064
862962019252	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-17
862962019253	HMMPfam hit to PF00593, TonB dependent receptor, score 4.5e-23
862962019254	Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; Region: MPP_ACP5; cd07378
862962019255	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
862962019256	active site
862962019257	metal binding site [ion binding]; metal-binding site
862962019258	Signal peptide predicted for BF638R4489 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.736 between residues 20 and 21
862962019259	1 probable transmembrane helix predicted for BF638R4489 by TMHMM2.0 at aa 5-22
862962019260	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.2e-15
862962019262	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 7.4e-39
862962019263	5 probable transmembrane helices predicted for BF638R4490 by TMHMM2.0 at aa 89-111, 150-172, 192-214, 247-269 and 279-301
862962019264	Signal peptide predicted for BF638R4491 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.241 between residues 25 and 26
862962019265	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
862962019266	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
862962019267	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
862962019268	Signal peptide predicted for BF638R4492 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.484 between residues 24 and 25
862962019269	10 probable transmembrane helices predicted for BF638R4492 by TMHMM2.0 at aa 5-27, 34-56, 71-93, 105-122, 132-154, 174-193, 208-230, 237-259, 274-291 and 298-317
862962019270	HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 1.7e-36
862962019271	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019272	HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 1.7e-43
862962019273	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019274	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
862962019275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
862962019276	ATP binding site [chemical binding]; other site
862962019277	Mg2+ binding site [ion binding]; other site
862962019278	G-X-G motif; other site
862962019279	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
862962019280	ATP binding site [chemical binding]; other site
862962019281	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
862962019282	active site
862962019283	putative metal-binding site [ion binding]; other site
862962019284	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
862962019285	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP, score 9.9e-13
862962019286	HMMPfam hit to PF00204, DNA gyrase B, score 2.2e-21
862962019287	PS00177 DNA topoisomerase II signature.
862962019288	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
862962019289	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
862962019290	active site
862962019291	(T/H)XGH motif; other site
862962019292	HMMPfam hit to PF01467, Cytidylyltransferase, score 2.7e-22
862962019293	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
862962019294	C-terminal peptidase (prc); Region: prc; TIGR00225
862962019295	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
862962019296	protein binding site [polypeptide binding]; other site
862962019297	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
862962019298	Catalytic dyad [active]
862962019299	Signal peptide predicted for BF638R4496 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.826 between residues 21 and 22
862962019300	1 probable transmembrane helix predicted for BF638R4496 by TMHMM2.0 at aa 7-24
862962019301	HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 5.9e-06
862962019302	HMMPfam hit to PF03572, Peptidase family S41, score 1.4e-72
862962019303	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
862962019304	active site
862962019305	4 probable transmembrane helices predicted for BF638R4497 by TMHMM2.0 at aa 44-66, 76-95, 143-161 and 171-193
862962019306	HMMPfam hit to PF01569, PAP2 superfamily, score 7.8e-23
862962019307	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019308	Signal peptide predicted for BF638R4497 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.846 between residues 19 and 20
862962019309	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962019310	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
862962019311	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.11
862962019312	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2e-05
862962019313	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
862962019314	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
862962019315	putative Iron-sulfur protein interface [polypeptide binding]; other site
862962019316	proximal heme binding site [chemical binding]; other site
862962019317	distal heme binding site [chemical binding]; other site
862962019318	putative dimer interface [polypeptide binding]; other site
862962019319	Signal peptide predicted for BF638R4499 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.424 between residues 35 and 36
862962019320	5 probable transmembrane helices predicted for BF638R4499 by TMHMM2.0 at aa 12-34, 54-76, 106-125, 160-182 and 203-222
862962019321	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
862962019322	L-aspartate oxidase; Provisional; Region: PRK06175
862962019323	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
862962019324	HMMPfam hit to PF00890, FAD binding domain, score 4.7e-51
862962019325	HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 1.3e-17
862962019326	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
862962019327	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
862962019328	PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
862962019329	HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00052
862962019330	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
862962019331	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
862962019332	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
862962019333	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
862962019334	4 probable transmembrane helices predicted for BF638R4502 by TMHMM2.0 at aa 12-34, 144-166, 198-220 and 349-371
862962019335	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.0085
862962019336	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.0022
862962019337	HMMPfam hit to PF03929, PepSY-associated TM helix, score 0.024
862962019338	Signal peptide predicted for BF638R4502 by SignalP 2.0 HMM (Signal peptide probability 0.815) with cleavage site probability 0.793 between residues 37 and 38
862962019339	Domain of unknown function (DUF4374); Region: DUF4374; pfam14298
862962019340	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019341	Signal peptide predicted for BF638R4503 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.908 between residues 22 and 23
862962019342	Cna protein B-type domain; Region: Cna_B_2; pfam13715
862962019343	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
862962019344	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
862962019345	HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-17
862962019346	HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.4e-18
862962019347	Signal peptide predicted for BF638R4504 by SignalP 2.0 HMM (Signal peptide probability 0.973) with cleavage site probability 0.340 between residues 28 and 29
862962019348	1 probable transmembrane helix predicted for BF638R4504 by TMHMM2.0 at aa 5-27
862962019349	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
862962019350	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.4e-05
862962019351	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.6
862962019352	PS00028 Zinc finger, C2H2 type, domain.
862962019353	Protein of unknown function (DUF3988); Region: DUF3988; pfam13149
862962019354	N-terminal domain found in Bacteroides fragilis Nctc 9343 BF2867 and related proteins; Region: BF2867_like_N; cd13120
862962019355	C-terminal domain found in Bacteroides fragilisNctc 9343 BF2867 and related proteins; Region: BF2867_like_C; cd13121
862962019356	Signal peptide predicted for BF638R4506 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.830 between residues 20 and 21
862962019357	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019358	Signal peptide predicted for BF638R4507 by SignalP 2.0 HMM (Signal peptide probability 0.815) with cleavage site probability 0.315 between residues 24 and 25
862962019359	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019360	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
862962019361	1 probable transmembrane helix predicted for BF638R4508 by TMHMM2.0 at aa 21-43
862962019362	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
862962019363	DNA protecting protein DprA; Region: dprA; TIGR00732
862962019364	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
862962019365	HMMPfam hit to PF02481, SMF family, score 5.5e-73
862962019366	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
862962019367	active site
862962019368	HMMPfam hit to PF03061, Thioesterase superfamily, score 3.9e-05
862962019369	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
862962019370	Class I aldolases; Region: Aldolase_Class_I; cl17187
862962019371	Peptidase family U32; Region: Peptidase_U32; pfam01136
862962019372	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
862962019373	HMMPfam hit to PF01136, Peptidase family U32, score 1.7e-67
862962019374	PS01276 Peptidase family U32 signature.
862962019375	Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; pfam09832
862962019376	Signal peptide predicted for BF638R4512 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 60 and 61
862962019377	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
862962019378	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
862962019379	FMN binding site [chemical binding]; other site
862962019380	active site
862962019381	catalytic residues [active]
862962019382	substrate binding site [chemical binding]; other site
862962019383	HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 4.8e-99
862962019384	PS01136 Uncharacterized protein family UPF0034 signature.
862962019385	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
862962019386	active site
862962019387	HMMPfam hit to PF01569, PAP2 superfamily, score 2.4e-05
862962019388	6 probable transmembrane helices predicted for BF638R4514 by TMHMM2.0 at aa 21-38, 53-75, 137-159, 163-185, 267-285 and 289-308
862962019389	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
862962019390	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
862962019391	NAD(P) binding site [chemical binding]; other site
862962019392	active site
862962019393	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
862962019394	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
862962019395	HMMPfam hit to PF01545, Cation efflux family, score 2.4e-89
862962019396	2 probable transmembrane helices predicted for BF638R4516 by TMHMM2.0 at aa 21-43 and 83-105
862962019397	ribonuclease R; Region: RNase_R; TIGR02063
862962019398	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
862962019399	RNB domain; Region: RNB; pfam00773
862962019400	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
862962019401	RNA binding site [nucleotide binding]; other site
862962019402	HMMPfam hit to PF00773, RNB-like protein, score 1.4e-126
862962019403	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
862962019404	PS01175 Ribonuclease II family signature.
862962019405	HMMPfam hit to PF00575, S1 RNA binding domain, score 9.6e-12
862962019406	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
862962019407	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
862962019408	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
862962019409	DNA binding residues [nucleotide binding]
862962019410	HMMPfam hit to PF04542, Sigma-70 region, score 4.8e-08
862962019411	4 probable transmembrane helices predicted for BF638R4520 by TMHMM2.0 at aa 40-62, 72-89, 128-146 and 150-172
862962019412	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
862962019413	HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 0.00074
862962019414	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
862962019415	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
862962019416	dimer interface [polypeptide binding]; other site
862962019417	pyridoxal 5'-phosphate binding site [chemical binding]; other site
862962019418	catalytic residue [active]
862962019419	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
862962019420	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.1e-126
862962019421	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
862962019422	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
862962019423	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
862962019424	substrate binding pocket [chemical binding]; other site
862962019425	PS00120 Lipases, serine active site.
862962019426	Signal peptide predicted for BF638R4524 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.978 between residues 18 and 19
862962019427	Signal peptide predicted for BF638R4525 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 21 and 22
862962019428	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
862962019429	GTP-binding protein YchF; Reviewed; Region: PRK09601
862962019430	YchF GTPase; Region: YchF; cd01900
862962019431	G1 box; other site
862962019432	GTP/Mg2+ binding site [chemical binding]; other site
862962019433	Switch I region; other site
862962019434	G2 box; other site
862962019435	Switch II region; other site
862962019436	G3 box; other site
862962019437	G4 box; other site
862962019438	G5 box; other site
862962019439	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
862962019440	PS00443 Glutamine amidotransferases class-II active site.
862962019441	HMMPfam hit to PF01926, GTPase of unknown function, score 3.4e-35
862962019442	PS00017 ATP/GTP-binding site motif A (P-loop).
862962019443	HMMPfam hit to PF06071, Protein of unknown function (DUF933), score 4.3e-61
862962019444	2-dehydropantoate 2-reductase; Region: apbA_panE; TIGR00745
862962019445	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
862962019446	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
862962019447	1 probable transmembrane helix predicted for BF638R4527 by TMHMM2.0 at aa 7-29
862962019448	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 2.3e-08
862962019449	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
862962019450	HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 6.2e-102
862962019451	7 probable transmembrane helices predicted for BF638R4528 by TMHMM2.0 at aa 22-44, 57-79, 105-127, 134-156, 187-209, 216-233 and 248-270
862962019452	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
862962019453	Chloramphenicol acetyltransferase; Region: CAT; smart01059
862962019454	HMMPfam hit to PF00302, Chloramphenicol acetyltransferase, score 7.4e-12
862962019455	1 probable transmembrane helix predicted for BF638R4529 by TMHMM2.0 at aa 177-196
862962019456	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
862962019457	MutS domain I; Region: MutS_I; pfam01624
862962019458	MutS domain II; Region: MutS_II; pfam05188
862962019459	MutS domain III; Region: MutS_III; pfam05192
862962019460	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
862962019461	Walker A/P-loop; other site
862962019462	ATP binding site [chemical binding]; other site
862962019463	Q-loop/lid; other site
862962019464	ABC transporter signature motif; other site
862962019465	Walker B; other site
862962019466	D-loop; other site
862962019467	H-loop/switch region; other site
862962019468	HMMPfam hit to PF00488, MutS domain V, score 4.3e-147
862962019469	PS00486 DNA mismatch repair proteins mutS family signature.
862962019470	PS00017 ATP/GTP-binding site motif A (P-loop).
862962019471	HMMPfam hit to PF05192, MutS domain III, score 1.4e-64
862962019472	HMMPfam hit to PF05190, MutS family domain IV, score 4.7e-35
862962019473	HMMPfam hit to PF05188, MutS domain II, score 1.5e-19
862962019474	PS00017 ATP/GTP-binding site motif A (P-loop).
862962019475	HMMPfam hit to PF01624, MutS domain I, score 6.6e-61
862962019476	Signal peptide predicted for BF638R4531 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.612 between residues 24 and 25
862962019477	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
862962019478	PS00017 ATP/GTP-binding site motif A (P-loop).
862962019479	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
862962019480	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962019481	active site
862962019482	HIGH motif; other site
862962019483	nucleotide binding site [chemical binding]; other site
862962019484	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962019485	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
862962019486	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962019487	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
862962019488	active site
862962019489	KMSKS motif; other site
862962019490	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
862962019491	tRNA binding surface [nucleotide binding]; other site
862962019492	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 3.4e-71
862962019493	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
862962019494	Uncharacterized conserved protein [Function unknown]; Region: COG1284
862962019495	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
862962019496	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
862962019497	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 8.5e-20
862962019498	6 probable transmembrane helices predicted for BF638R4533 by TMHMM2.0 at aa 17-39, 49-71, 83-105, 120-142, 162-184 and 189-208
862962019499	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.2e-19
862962019500	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
862962019501	active site
862962019502	dimerization interface [polypeptide binding]; other site
862962019503	HMMPfam hit to PF01725, Ham1 family, score 9.9e-76
862962019504	quinolinate synthetase; Provisional; Region: PRK09375
862962019505	HMMPfam hit to PF02445, Quinolinate synthetase A protein, score 1.5e-175