-- dump date 20140619_002024 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002967461.1 241190067 8009622 134..1885 1 NC_012814.1 COG0593 ATPase involved in DNA replication initiation; ATPase for DNA replication initiation 1885 dnaA 8009622 dnaA Bifidobacterium animalis subsp. lactis Bl-04 ATPase for DNA replication initiation YP_002967461.1 134 D 580050 CDS YP_002967462.1 241190068 8007993 2489..3613 1 NC_012814.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3613 8007993 Balac_0002 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunit beta YP_002967462.1 2489 D 580050 CDS YP_002967463.1 241190069 8007994 3659..5086 1 NC_012814.1 COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein RecF 5086 8007994 Balac_0003 Bifidobacterium animalis subsp. lactis Bl-04 recombination protein RecF YP_002967463.1 3659 D 580050 CDS YP_002967464.1 241190070 8007995 5083..5586 1 NC_012814.1 COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; hypothetical protein 5586 8007995 Balac_0004 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967464.1 5083 D 580050 CDS YP_002967465.1 241190071 8007996 5777..7894 1 NC_012814.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 7894 gyrB 8007996 gyrB Bifidobacterium animalis subsp. lactis Bl-04 DNA gyrase subunit B YP_002967465.1 5777 D 580050 CDS YP_002967466.1 241190072 8007997 7963..10725 1 NC_012814.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 10725 8007997 Balac_0006 Bifidobacterium animalis subsp. lactis Bl-04 DNA gyrase subunit A YP_002967466.1 7963 D 580050 CDS YP_002967467.1 241190073 8007998 10851..11387 1 NC_012814.1 hypothetical protein 11387 8007998 Balac_0007 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967467.1 10851 D 580050 CDS YP_002967468.1 241190074 8007999 11591..12664 1 NC_012814.1 COG4767 Glycopeptide antibiotics resistance protein; hypothetical protein 12664 8007999 Balac_0008 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967468.1 11591 D 580050 CDS YP_002967469.1 241190075 8008000 complement(12745..13539) 1 NC_012814.1 COG1272 Predicted membrane protein, hemolysin III homolog; putative hemolysin III-like membrane protein 13539 8008000 Balac_0009 Bifidobacterium animalis subsp. lactis Bl-04 putative hemolysin III-like membrane protein YP_002967469.1 12745 R 580050 CDS YP_002967470.1 241190076 8008001 complement(14018..15364) 1 NC_012814.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 15364 8008001 Balac_0010 Bifidobacterium animalis subsp. lactis Bl-04 glutamate dehydrogenase YP_002967470.1 14018 R 580050 CDS YP_002967471.1 241190077 8008002 complement(15477..16799) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; multidrug transport protein 16799 8008002 Balac_0011 Bifidobacterium animalis subsp. lactis Bl-04 multidrug transport protein YP_002967471.1 15477 R 580050 CDS YP_002967472.1 241190078 8008003 16847..16990 1 NC_012814.1 hypothetical protein 16990 8008003 Balac_0012 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967472.1 16847 D 580050 CDS YP_002967473.1 241190079 8008004 16983..18170 1 NC_012814.1 mannan endo-1,4-beta-mannosidase 18170 8008004 Balac_0013 Bifidobacterium animalis subsp. lactis Bl-04 mannan endo-1,4-beta-mannosidase YP_002967473.1 16983 D 580050 CDS YP_002967474.1 241190080 8008005 18418..18918 1 NC_012814.1 COG1970 Large-conductance mechanosensitive channel; large-conductance mechanosensitive channel 18918 8008005 Balac_0014 Bifidobacterium animalis subsp. lactis Bl-04 large-conductance mechanosensitive channel YP_002967474.1 18418 D 580050 CDS YP_002967475.1 241190081 8008006 19174..19449 1 NC_012814.1 COG2308 Uncharacterized conserved protein; hypothetical protein 19449 8008006 Balac_0015 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967475.1 19174 D 580050 CDS YP_002967476.1 241190082 8009559 19968..20732 1 NC_012814.1 COG1451 Predicted metal-dependent hydrolase; hypothetical protein 20732 8009559 Balac_0018 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967476.1 19968 D 580050 CDS YP_002967477.1 241190083 8008008 complement(20757..21182) 1 NC_012814.1 membrane-anchored glycerophosphoryl diesterphosphodiesterase-like protein 21182 8008008 Balac_0019 Bifidobacterium animalis subsp. lactis Bl-04 membrane-anchored glycerophosphoryl diesterphosphodiesterase-like protein YP_002967477.1 20757 R 580050 CDS YP_002967478.1 241190084 8008009 complement(21820..22608) 1 NC_012814.1 COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; putative transcriptional regulator 22608 8008009 Balac_0020 Bifidobacterium animalis subsp. lactis Bl-04 putative transcriptional regulator YP_002967478.1 21820 R 580050 CDS YP_002967479.1 241190085 8008010 22644..22898 1 NC_012814.1 hypothetical protein 22898 8008010 Balac_0021 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967479.1 22644 D 580050 CDS YP_002967480.1 241190086 8008011 23538..26039 1 NC_012814.1 COG0178 Excinuclease ATPase subunit; ABC transporter 26039 8008011 Balac_0022 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002967480.1 23538 D 580050 CDS YP_002967481.1 241190087 8008012 26398..27153 1 NC_012814.1 COG0500 SAM-dependent methyltransferases; methyltransferase 27153 8008012 Balac_0023 Bifidobacterium animalis subsp. lactis Bl-04 methyltransferase YP_002967481.1 26398 D 580050 CDS YP_002967482.1 241190088 8008013 27202..28116 1 NC_012814.1 hypothetical protein 28116 8008013 Balac_0024 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967482.1 27202 D 580050 CDS YP_002967483.1 241190089 8008014 28439..29038 1 NC_012814.1 COG0431 Predicted flavoprotein; oxidoreductase 29038 8008014 Balac_0025 Bifidobacterium animalis subsp. lactis Bl-04 oxidoreductase YP_002967483.1 28439 D 580050 CDS YP_002967484.1 241190090 8008015 29241..29954 1 NC_012814.1 hypothetical protein 29954 8008015 Balac_0026 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967484.1 29241 D 580050 CDS YP_002967485.1 241190091 8008016 30678..30914 1 NC_012814.1 COG1198 Primosomal protein N (replication factor Y - superfamily II helicase); hypothetical protein 30914 8008016 Balac_0027 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967485.1 30678 D 580050 CDS YP_002967486.1 241190092 8008017 31096..31371 1 NC_012814.1 hypothetical protein 31371 8008017 Balac_0028 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967486.1 31096 D 580050 CDS YP_002967487.1 241190093 8008018 31555..31824 1 NC_012814.1 hypothetical protein 31824 8008018 Balac_0029 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967487.1 31555 D 580050 CDS YP_002967488.1 241190094 8008019 complement(31962..32285) 1 NC_012814.1 COG1694 Predicted pyrophosphatase; MazG nucleotide pyrophosphohydrolase domain-containing protein 32285 8008019 Balac_0030 Bifidobacterium animalis subsp. lactis Bl-04 MazG nucleotide pyrophosphohydrolase domain-containing protein YP_002967488.1 31962 R 580050 CDS YP_002967489.1 241190095 8008020 32313..32663 1 NC_012814.1 hypothetical protein 32663 8008020 Balac_0031 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967489.1 32313 D 580050 CDS YP_002967490.1 241190096 8008021 32673..33755 1 NC_012814.1 hypothetical protein 33755 8008021 Balac_0032 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967490.1 32673 D 580050 CDS YP_002967491.1 241190097 8008022 33890..34099 1 NC_012814.1 hypothetical protein 34099 8008022 Balac_0033 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967491.1 33890 D 580050 CDS YP_002967492.1 241190098 8008023 34600..35961 1 NC_012814.1 COG0270 Site-specific DNA methylase; site-specific DNA-methyltransferase 35961 8008023 Balac_0034 Bifidobacterium animalis subsp. lactis Bl-04 site-specific DNA-methyltransferase YP_002967492.1 34600 D 580050 CDS YP_002967493.1 241190099 8008024 complement(36056..36901) 1 NC_012814.1 hypothetical protein 36901 8008024 Balac_0035 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967493.1 36056 R 580050 CDS YP_002967494.1 241190100 8008025 37469..39892 1 NC_012814.1 hypothetical protein 39892 8008025 Balac_0036 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967494.1 37469 D 580050 CDS YP_002967495.1 241190101 8008026 complement(39920..40501) 1 NC_012814.1 hypothetical protein 40501 8008026 Balac_0037 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967495.1 39920 R 580050 CDS YP_002967496.1 241190102 8008027 complement(40482..42617) 1 NC_012814.1 hypothetical protein 42617 8008027 Balac_0038 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967496.1 40482 R 580050 CDS YP_002967497.1 241190103 8008028 42959..43327 1 NC_012814.1 hypothetical protein 43327 8008028 Balac_0039 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967497.1 42959 D 580050 CDS YP_002967498.1 241190104 8008029 43526..43639 1 NC_012814.1 hypothetical protein 43639 8008029 Balac_0040 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967498.1 43526 D 580050 CDS YP_002967499.1 241190105 8008030 44261..44464 1 NC_012814.1 hypothetical protein 44464 8008030 Balac_0041 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967499.1 44261 D 580050 CDS YP_002967500.1 241190106 8008031 complement(44728..44958) 1 NC_012814.1 COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 44958 8008031 Balac_0042 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967500.1 44728 R 580050 CDS YP_002967501.1 241190107 8008032 complement(45029..45178) 1 NC_012814.1 hypothetical protein 45178 8008032 Balac_0043 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967501.1 45029 R 580050 CDS YP_002967502.1 241190108 8008033 45214..45474 1 NC_012814.1 COG2336 Growth regulator; hypothetical protein 45474 8008033 Balac_0044 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967502.1 45214 D 580050 CDS YP_002967503.1 241190109 8008034 45476..45859 1 NC_012814.1 COG2337 Growth inhibitor; transcriptional modulator of MazE/toxin, MazF 45859 8008034 Balac_0045 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional modulator of MazE/toxin, MazF YP_002967503.1 45476 D 580050 CDS YP_002967504.1 241190110 8008035 complement(46047..46937) 1 NC_012814.1 COG0583 Transcriptional regulator; transcriptional regulator 46937 8008035 Balac_0046 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002967504.1 46047 R 580050 CDS YP_002967505.1 241190111 8008036 47066..47329 1 NC_012814.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 47329 8008036 Balac_0047 Bifidobacterium animalis subsp. lactis Bl-04 aldo/keto reductase YP_002967505.1 47066 D 580050 CDS YP_002967506.1 241190112 8008037 47292..47942 1 NC_012814.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 47942 8008037 Balac_0048 Bifidobacterium animalis subsp. lactis Bl-04 aldo/keto reductase YP_002967506.1 47292 D 580050 CDS YP_002967507.1 241190113 8008038 complement(48034..50283) 1 NC_012814.1 COG1472 Beta-glucosidase-related glycosidases; putative beta-glucosidase 50283 8008038 Balac_0049 Bifidobacterium animalis subsp. lactis Bl-04 putative beta-glucosidase YP_002967507.1 48034 R 580050 CDS YP_002967508.1 241190114 8008039 51542..51979 1 NC_012814.1 hypothetical protein 51979 8008039 Balac_0050 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967508.1 51542 D 580050 CDS YP_002967509.1 241190115 8008040 complement(52309..53442) 1 NC_012814.1 COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 53442 8008040 Balac_0051 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS204/IS1001/IS1096/IS1165 family protein YP_002967509.1 52309 R 580050 CDS YP_002967510.1 241190116 8008041 53714..55240 1 NC_012814.1 COG5520 O-Glycosyl hydrolase; glycoside hydrolase family protein 55240 8008041 Balac_0052 Bifidobacterium animalis subsp. lactis Bl-04 glycoside hydrolase family protein YP_002967510.1 53714 D 580050 CDS YP_002967511.1 241190117 8008042 complement(55366..57471) 1 NC_012814.1 COG1874 Beta-galactosidase; beta-galactosidase I 57471 8008042 Balac_0053 Bifidobacterium animalis subsp. lactis Bl-04 beta-galactosidase I YP_002967511.1 55366 R 580050 CDS YP_002967512.1 241190118 8008043 57881..59035 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; glycoside-Pentoside-hexuronide 59035 8008043 Balac_0054 Bifidobacterium animalis subsp. lactis Bl-04 glycoside-Pentoside-hexuronide YP_002967512.1 57881 D 580050 CDS YP_002967513.1 241190119 8008044 complement(59090..59731) 1 NC_012814.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 59731 8008044 Balac_0055 Bifidobacterium animalis subsp. lactis Bl-04 TetR family transcriptional regulator YP_002967513.1 59090 R 580050 CDS YP_002967514.1 241190120 8008045 complement(59884..60366) 1 NC_012814.1 COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA-binding ferritin-like protein for protection from oxidative damage 60366 8008045 Balac_0056 Bifidobacterium animalis subsp. lactis Bl-04 DNA-binding ferritin-like protein for protection from oxidative damage YP_002967514.1 59884 R 580050 CDS YP_002967515.1 241190121 8008046 complement(60491..61846) 1 NC_012814.1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysin-like protein 61846 8008046 Balac_0057 Bifidobacterium animalis subsp. lactis Bl-04 hemolysin-like protein YP_002967515.1 60491 R 580050 CDS YP_002967516.1 241190122 8008047 complement(62130..62759) 1 NC_012814.1 COG0288 Carbonic anhydrase; carbonic anhydrase 62759 8008047 Balac_0058 Bifidobacterium animalis subsp. lactis Bl-04 carbonic anhydrase YP_002967516.1 62130 R 580050 CDS YP_002967517.1 241190123 8008048 62901..64016 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 64016 8008048 Balac_0059 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002967517.1 62901 D 580050 CDS YP_002967518.1 241190124 8008049 complement(64069..64296) 1 NC_012814.1 hypothetical protein 64296 8008049 Balac_0060 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967518.1 64069 R 580050 CDS YP_002967519.1 241190125 8008050 complement(64454..64624) 1 NC_012814.1 COG4214 ABC-type xylose transport system, permease component; ABC-type xylose transport system permease 64624 8008050 Balac_0061 Bifidobacterium animalis subsp. lactis Bl-04 ABC-type xylose transport system permease YP_002967519.1 64454 R 580050 CDS YP_002967520.1 241190126 8008051 64619..65323 1 NC_012814.1 COG1129 ABC-type sugar transport system, ATPase component; pentose ABC transporter ATP binding protein 65323 8008051 Balac_0062 Bifidobacterium animalis subsp. lactis Bl-04 pentose ABC transporter ATP binding protein YP_002967520.1 64619 D 580050 CDS YP_002967521.1 241190127 8008052 65524..65865 1 NC_012814.1 hypothetical protein 65865 8008052 Balac_0063 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967521.1 65524 D 580050 CDS YP_002967522.1 241190128 8008053 complement(65860..66894) 1 NC_012814.1 COG1609 Transcriptional regulators; RbsR-type transcription regulator/ ribose operon repressor 66894 8008053 Balac_0064 Bifidobacterium animalis subsp. lactis Bl-04 RbsR-type transcription regulator/ ribose operon repressor YP_002967522.1 65860 R 580050 CDS YP_002967523.1 241190129 8008054 complement(67012..68553) 1 NC_012814.1 COG3534 Alpha-L-arabinofuranosidase; alpha-L-arabinofuranosidase 68553 8008054 Balac_0065 Bifidobacterium animalis subsp. lactis Bl-04 alpha-L-arabinofuranosidase YP_002967523.1 67012 R 580050 CDS YP_002967524.1 241190130 8008055 68830..70491 1 NC_012814.1 COG1070 Sugar (pentulose and hexulose kinases); sugar kinase 70491 8008055 Balac_0066 Bifidobacterium animalis subsp. lactis Bl-04 sugar kinase YP_002967524.1 68830 D 580050 CDS YP_002967525.1 241190131 8008056 70547..71239 1 NC_012814.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 71239 8008056 Balac_0067 Bifidobacterium animalis subsp. lactis Bl-04 L-ribulose-5-phosphate 4-epimerase YP_002967525.1 70547 D 580050 CDS YP_002967526.1 241190132 8008057 71503..73020 1 NC_012814.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 73020 8008057 Balac_0068 Bifidobacterium animalis subsp. lactis Bl-04 L-arabinose isomerase YP_002967526.1 71503 D 580050 CDS YP_002967527.1 241190133 8008058 73155..74018 1 NC_012814.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; dehydrogenase or reductase protein 74018 8008058 Balac_0069 Bifidobacterium animalis subsp. lactis Bl-04 dehydrogenase or reductase protein YP_002967527.1 73155 D 580050 CDS YP_002967528.1 241190134 8008059 complement(74259..77015) 1 NC_012814.1 COG2352 Phosphoenolpyruvate carboxylase; hypothetical protein 77015 8008059 Balac_0070 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967528.1 74259 R 580050 CDS YP_002967529.1 241190135 8008060 77254..79002 1 NC_012814.1 COG2966 Uncharacterized conserved protein; hypothetical protein 79002 8008060 Balac_0071 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967529.1 77254 D 580050 CDS YP_002967530.1 241190136 8008061 complement(79093..80226) 1 NC_012814.1 COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 80226 8008061 Balac_0072 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS204/IS1001/IS1096/IS1165 family protein YP_002967530.1 79093 R 580050 CDS YP_002967531.1 241190137 8008062 complement(80579..81682) 1 NC_012814.1 COG0180 Tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase 81682 8008062 Balac_0073 Bifidobacterium animalis subsp. lactis Bl-04 Tryptophanyl-tRNA synthetase YP_002967531.1 80579 R 580050 CDS YP_002967532.1 241190138 8008063 81843..82190 1 NC_012814.1 hypothetical protein 82190 8008063 Balac_0074 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967532.1 81843 D 580050 CDS YP_002967533.1 241190139 8008064 complement(82389..82772) 1 NC_012814.1 hypothetical protein 82772 8008064 Balac_0075 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967533.1 82389 R 580050 CDS YP_002967534.1 241190140 8008065 83374..85830 1 NC_012814.1 COG0058 Glucan phosphorylase; glycogen phosphorylase 85830 8008065 Balac_0076 Bifidobacterium animalis subsp. lactis Bl-04 glycogen phosphorylase YP_002967534.1 83374 D 580050 CDS YP_002967535.1 241190141 8008066 complement(86071..86298) 1 NC_012814.1 hypothetical protein 86298 8008066 Balac_0077 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967535.1 86071 R 580050 CDS YP_002967536.1 241190142 8008067 86641..87342 1 NC_012814.1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); rhomboid family membrane protein 87342 8008067 Balac_0078 Bifidobacterium animalis subsp. lactis Bl-04 rhomboid family membrane protein YP_002967536.1 86641 D 580050 CDS YP_002967537.1 241190143 8008068 88340..89746 1 NC_012814.1 COG0500 SAM-dependent methyltransferases; N6-adenine-specific methylase 89746 8008068 Balac_0079 Bifidobacterium animalis subsp. lactis Bl-04 N6-adenine-specific methylase YP_002967537.1 88340 D 580050 CDS YP_002967538.1 241190144 8008069 complement(90000..90575) 1 NC_012814.1 integral membrane protein involved in inhibition of the Z-ring formation; putative septation inhibitor protein 90575 8008069 Balac_0080 Bifidobacterium animalis subsp. lactis Bl-04 putative septation inhibitor protein YP_002967538.1 90000 R 580050 CDS YP_002967539.1 241190145 8008070 90682..91479 1 NC_012814.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 91479 8008070 Balac_0081 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967539.1 90682 D 580050 CDS YP_002967540.1 241190146 8008071 91567..92721 1 NC_012814.1 COG3764 Sortase (surface protein transpeptidase); hypothetical protein 92721 8008071 Balac_0082 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967540.1 91567 D 580050 CDS YP_002967541.1 241190147 8008072 92962..93609 1 NC_012814.1 COG0512 Anthranilate/para-aminobenzoate synthases component II; Para-aminobenzoate synthase glutamineamidotransferase component II 93609 8008072 Balac_0083 Bifidobacterium animalis subsp. lactis Bl-04 Para-aminobenzoate synthase glutamineamidotransferase component II YP_002967541.1 92962 D 580050 CDS YP_002967542.1 241190148 8008073 complement(93919..96051) 1 NC_012814.1 COG0515 Serine/threonine protein kinase; serine-threonine protein kinase 96051 8008073 Balac_0084 Bifidobacterium animalis subsp. lactis Bl-04 serine-threonine protein kinase YP_002967542.1 93919 R 580050 CDS YP_002967543.1 241190149 8008074 complement(96044..97069) 1 NC_012814.1 COG0515 Serine/threonine protein kinase; serine-threonine protein kinase 97069 8008074 Balac_0085 Bifidobacterium animalis subsp. lactis Bl-04 serine-threonine protein kinase YP_002967543.1 96044 R 580050 CDS YP_002967544.1 241190150 8008075 complement(97066..98532) 1 NC_012814.1 COG0768 Cell division proteinFtsI/penicillin-binding protein 2; penicillin binding protein transpeptidase 98532 8008075 Balac_0086 Bifidobacterium animalis subsp. lactis Bl-04 penicillin binding protein transpeptidase YP_002967544.1 97066 R 580050 CDS YP_002967545.1 241190151 8008076 complement(98525..100267) 1 NC_012814.1 COG0772 Bacterial cell division membrane protein; cell division membrane protein 100267 8008076 Balac_0087 Bifidobacterium animalis subsp. lactis Bl-04 cell division membrane protein YP_002967545.1 98525 R 580050 CDS YP_002967546.1 241190152 8008077 complement(100270..101808) 1 NC_012814.1 COG0631 Serine/threonine protein phosphatase; phosphoprotein phosphatase 101808 8008077 Balac_0088 Bifidobacterium animalis subsp. lactis Bl-04 phosphoprotein phosphatase YP_002967546.1 100270 R 580050 CDS YP_002967547.1 241190153 8008078 complement(101830..102375) 1 NC_012814.1 COG1716 FOG: FHA domain; hypothetical protein 102375 8008078 Balac_0089 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967547.1 101830 R 580050 CDS YP_002967548.1 241190154 8008079 complement(102394..103095) 1 NC_012814.1 COG1716 FOG: FHA domain; hypothetical protein 103095 8008079 Balac_0090 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967548.1 102394 R 580050 CDS YP_002967549.1 241190155 8008080 103860..106274 1 NC_012814.1 COG1506 Dipeptidylaminopeptidases/acylaminoacyl-peptidases; Dipeptidylaminopeptidase/acylaminoacyl- peptidase 106274 8008080 Balac_0091 Bifidobacterium animalis subsp. lactis Bl-04 Dipeptidylaminopeptidase/acylaminoacyl- peptidase YP_002967549.1 103860 D 580050 CDS YP_002967550.1 241190156 8008081 complement(106313..107365) 1 NC_012814.1 COG0697 Permeases of the drug/metabolite transporter (DMT superfamily); putative permease 107365 8008081 Balac_0092 Bifidobacterium animalis subsp. lactis Bl-04 putative permease YP_002967550.1 106313 R 580050 CDS YP_002967551.1 241190157 8008082 complement(107450..108535) 1 NC_012814.1 COG2267 Lysophospholipase; hypothetical protein 108535 8008082 Balac_0093 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967551.1 107450 R 580050 CDS YP_002967552.1 241190158 8008083 108714..109052 1 NC_012814.1 hypothetical protein 109052 8008083 Balac_0094 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967552.1 108714 D 580050 CDS YP_002967553.1 241190159 8008084 109132..110085 1 NC_012814.1 COG0500 SAM-dependent methyltransferases; methyltransferase 110085 8008084 Balac_0095 Bifidobacterium animalis subsp. lactis Bl-04 methyltransferase YP_002967553.1 109132 D 580050 CDS YP_002967554.1 241190160 8008085 complement(110587..110841) 1 NC_012814.1 COG2261 Predicted membrane protein; hypothetical protein 110841 8008085 Balac_0096 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967554.1 110587 R 580050 CDS YP_002967555.1 241190161 8008086 complement(111113..111370) 1 NC_012814.1 COG2261 Predicted membrane protein; hypothetical protein 111370 8008086 Balac_0097 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967555.1 111113 R 580050 CDS YP_002967556.1 241190162 8009560 complement(112141..113589) 1 NC_012814.1 COG0493 NADPH-dependent glutamate synthase betachain and related oxidoreductases; ferredoxin/ferredoxin-NADP reductase 113589 8009560 Balac_0099 Bifidobacterium animalis subsp. lactis Bl-04 ferredoxin/ferredoxin-NADP reductase YP_002967556.1 112141 R 580050 CDS YP_002967557.1 241190163 8008088 complement(113779..116013) 1 NC_012814.1 COG2217 Cation transport ATPase; cation-transporting ATPase V 116013 8008088 Balac_0100 Bifidobacterium animalis subsp. lactis Bl-04 cation-transporting ATPase V YP_002967557.1 113779 R 580050 CDS YP_002967558.1 241190164 8008089 complement(116322..118163) 1 NC_012814.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; DO serine protease 118163 8008089 Balac_0101 Bifidobacterium animalis subsp. lactis Bl-04 DO serine protease YP_002967558.1 116322 R 580050 CDS YP_002967559.1 241190165 8008090 118338..118952 1 NC_012814.1 COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase 118952 8008090 Balac_0102 Bifidobacterium animalis subsp. lactis Bl-04 alpha beta hydrolase YP_002967559.1 118338 D 580050 CDS YP_002967560.1 241190166 8008091 119450..120979 1 NC_012814.1 COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 120979 8008091 Balac_0103 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967560.1 119450 D 580050 CDS YP_002967561.1 241190167 8008092 121079..122416 1 NC_012814.1 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 122416 8008092 Balac_0104 Bifidobacterium animalis subsp. lactis Bl-04 queuine tRNA-ribosyltransferase YP_002967561.1 121079 D 580050 CDS YP_002967562.1 241190168 8009561 complement(122644..123615) 1 NC_012814.1 putative metalloprotease; heat shock protein HtpX 123615 8009561 Balac_0106 Bifidobacterium animalis subsp. lactis Bl-04 heat shock protein HtpX YP_002967562.1 122644 R 580050 CDS YP_002967563.1 241190169 8008094 complement(123665..124825) 1 NC_012814.1 hypothetical protein 124825 8008094 Balac_0107 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967563.1 123665 R 580050 CDS YP_002967564.1 241190170 8008095 124983..125624 1 NC_012814.1 COG2135 Uncharacterized conserved protein; hypothetical protein 125624 8008095 Balac_0108 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967564.1 124983 D 580050 CDS YP_002967565.1 241190171 8008096 125727..126971 1 NC_012814.1 COG2814 Arabinose efflux permease; AraJ-like protein 126971 8008096 Balac_0109 Bifidobacterium animalis subsp. lactis Bl-04 AraJ-like protein YP_002967565.1 125727 D 580050 CDS YP_002967566.1 241190172 8008097 complement(127054..127317) 1 NC_012814.1 hypothetical protein 127317 8008097 Balac_0110 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967566.1 127054 R 580050 CDS YP_002967567.1 241190173 8008098 complement(127630..127935) 1 NC_012814.1 COG3077 DNA-damage-inducible protein J; hypothetical protein 127935 8008098 Balac_0111 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967567.1 127630 R 580050 CDS YP_002967568.1 241190174 8008099 complement(127988..128467) 1 NC_012814.1 COG0350 Methylated DNA-protein cysteinemethyltransferase; methylated-DNA--protein- cysteinemethyltransferase 128467 8008099 Balac_0112 Bifidobacterium animalis subsp. lactis Bl-04 methylated-DNA--protein- cysteinemethyltransferase YP_002967568.1 127988 R 580050 CDS YP_002967569.1 241190175 8008100 128864..130081 1 NC_012814.1 oxidoreductase 130081 8008100 Balac_0113 Bifidobacterium animalis subsp. lactis Bl-04 oxidoreductase YP_002967569.1 128864 D 580050 CDS YP_002967570.1 241190176 8008101 complement(130041..130808) 1 NC_012814.1 COG0599 Uncharacterized homolog ofgamma-carboxymuconolactone decarboxylase subunit; putative carboxymuconolactone decarboxylase 130808 8008101 Balac_0114 Bifidobacterium animalis subsp. lactis Bl-04 putative carboxymuconolactone decarboxylase YP_002967570.1 130041 R 580050 CDS YP_002967571.1 241190177 8008102 complement(130832..131275) 1 NC_012814.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; carboxymuconolactone decarboxylase 131275 8008102 Balac_0115 Bifidobacterium animalis subsp. lactis Bl-04 carboxymuconolactone decarboxylase YP_002967571.1 130832 R 580050 CDS YP_002967572.1 241190178 8008103 complement(131417..132403) 1 NC_012814.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 132403 8008103 Balac_0116 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967572.1 131417 R 580050 CDS YP_002967573.1 241190179 8008104 132538..133407 1 NC_012814.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 133407 8008104 Balac_0117 Bifidobacterium animalis subsp. lactis Bl-04 LysR family transcriptional regulator YP_002967573.1 132538 D 580050 CDS YP_002967574.1 241190180 8008105 complement(133448..134473) 1 NC_012814.1 COG0667 Predicted oxidoreductases (related toaryl-alcohol dehydrogenases); Tas protein 134473 8008105 Balac_0118 Bifidobacterium animalis subsp. lactis Bl-04 Tas protein YP_002967574.1 133448 R 580050 CDS YP_002967575.1 241190181 8008106 complement(134530..134712) 1 NC_012814.1 hypothetical protein 134712 8008106 Balac_0119 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967575.1 134530 R 580050 CDS YP_002967576.1 241190182 8008107 complement(134766..136061) 1 NC_012814.1 COG4097 Predicted ferric reductase; ferric reductase 136061 8008107 Balac_0120 Bifidobacterium animalis subsp. lactis Bl-04 ferric reductase YP_002967576.1 134766 R 580050 CDS YP_002967577.1 241190183 8008108 complement(136098..136754) 1 NC_012814.1 COG0716 Flavodoxins; hypothetical protein 136754 8008108 Balac_0121 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967577.1 136098 R 580050 CDS YP_002967578.1 241190184 8008109 136744..137493 1 NC_012814.1 COG0789 Predicted transcriptional regulators; transcriptional regulator 137493 8008109 Balac_0122 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002967578.1 136744 D 580050 CDS YP_002967579.1 241190185 8008110 complement(137546..138019) 1 NC_012814.1 COG0716 Flavodoxins; flavodoxin 138019 8008110 Balac_0123 Bifidobacterium animalis subsp. lactis Bl-04 flavodoxin YP_002967579.1 137546 R 580050 CDS YP_002967580.1 241190186 8008111 complement(138087..138875) 1 NC_012814.1 COG0702 Predicted nucleoside-diphosphate-sugare pimerases; NAD-dependent epimerase/dehydratase 138875 8008111 Balac_0124 Bifidobacterium animalis subsp. lactis Bl-04 NAD-dependent epimerase/dehydratase YP_002967580.1 138087 R 580050 CDS YP_002967581.1 241190187 8008112 complement(138893..139951) 1 NC_012814.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase 139951 8008112 Balac_0125 Bifidobacterium animalis subsp. lactis Bl-04 alcohol dehydrogenase YP_002967581.1 138893 R 580050 CDS YP_002967582.1 241190188 8008113 140142..141041 1 NC_012814.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 141041 8008113 Balac_0126 Bifidobacterium animalis subsp. lactis Bl-04 LysR family transcriptional regulator YP_002967582.1 140142 D 580050 CDS YP_002967583.1 241190189 8008114 complement(141044..142354) 1 NC_012814.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 142354 8008114 Balac_0127 Bifidobacterium animalis subsp. lactis Bl-04 polysaccharide deacetylase YP_002967583.1 141044 R 580050 CDS YP_002967584.1 241190190 8008115 142498..143562 1 NC_012814.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 143562 8008115 Balac_0128 Bifidobacterium animalis subsp. lactis Bl-04 fructose-bisphosphate aldolase YP_002967584.1 142498 D 580050 CDS YP_002967585.1 241190191 8008116 144115..145401 1 NC_012814.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 145401 8008116 Balac_0129 Bifidobacterium animalis subsp. lactis Bl-04 adenylosuccinate synthetase YP_002967585.1 144115 D 580050 CDS YP_002967586.1 241190192 8008117 145542..146474 1 NC_012814.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 146474 8008117 Balac_0130 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967586.1 145542 D 580050 CDS YP_002967587.1 241190193 8008118 146474..146848 1 NC_012814.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 146848 8008118 Balac_0131 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967587.1 146474 D 580050 CDS YP_002967588.1 241190194 8008119 147437..148873 1 NC_012814.1 COG0559 Branched-chain amino acid ABC-typetransport system, permease components; branched-chain amino acid ABC-type transport system permease 148873 8008119 Balac_0132 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid ABC-type transport system permease YP_002967588.1 147437 D 580050 CDS YP_002967589.1 241190195 8008120 148877..149860 1 NC_012814.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; branched-chain amino acid transport system permease 149860 8008120 Balac_0133 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid transport system permease YP_002967589.1 148877 D 580050 CDS YP_002967590.1 241190196 8008121 149853..150860 1 NC_012814.1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid transport systemATP-binding protein 150860 8008121 Balac_0134 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid transport systemATP-binding protein YP_002967590.1 149853 D 580050 CDS YP_002967591.1 241190197 8008122 150853..151668 1 NC_012814.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 151668 8008122 Balac_0135 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid ABC transporter ATPase YP_002967591.1 150853 D 580050 CDS YP_002967592.1 241190198 8008123 151811..153076 1 NC_012814.1 COG0683 ABC-type branched-chain amino acidtransport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein 153076 8008123 Balac_0136 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid transport system substrate-binding protein YP_002967592.1 151811 D 580050 CDS YP_002967593.1 241190199 8008124 complement(153154..154182) 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 154182 8008124 Balac_0137 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002967593.1 153154 R 580050 CDS YP_002967594.1 241190200 8008125 154489..156009 1 NC_012814.1 COG0366 Glycosidases; sucrose phosphorylase 156009 8008125 Balac_0138 Bifidobacterium animalis subsp. lactis Bl-04 sucrose phosphorylase YP_002967594.1 154489 D 580050 CDS YP_002967595.1 241190201 8008126 156066..157679 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; transport membrane protein 157679 8008126 Balac_0139 Bifidobacterium animalis subsp. lactis Bl-04 transport membrane protein YP_002967595.1 156066 D 580050 CDS YP_002967596.1 241190202 8008127 157945..158664 1 NC_012814.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein 158664 8008127 Balac_0140 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid transport system substrate-binding protein YP_002967596.1 157945 D 580050 CDS YP_002967597.1 241190203 8008128 158700..159998 1 NC_012814.1 COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; biotin carboxylase/biotin carboxyl carrier protein 159998 8008128 Balac_0141 Bifidobacterium animalis subsp. lactis Bl-04 biotin carboxylase/biotin carboxyl carrier protein YP_002967597.1 158700 D 580050 CDS YP_002967598.1 241190204 8008129 160347..161306 1 NC_012814.1 hypothetical protein 161306 8008129 Balac_0142 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967598.1 160347 D 580050 CDS YP_002967599.1 241190205 8008130 161412..163001 1 NC_012814.1 COG2211 Na+/melibiose symporter and related transporters; Na+/sugar symporter 163001 8008130 Balac_0143 Bifidobacterium animalis subsp. lactis Bl-04 Na+/sugar symporter YP_002967599.1 161412 D 580050 CDS YP_002967600.1 241190206 8008131 complement(163021..163527) 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 163527 8008131 Balac_0144 Bifidobacterium animalis subsp. lactis Bl-04 GCN5-like N-acetyltransferase YP_002967600.1 163021 R 580050 CDS YP_002967601.1 241190207 8008132 complement(163524..163808) 1 NC_012814.1 COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein 163808 8008132 Balac_0145 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967601.1 163524 R 580050 CDS YP_002967602.1 241190208 8008133 163938..164066 1 NC_012814.1 hypothetical protein 164066 8008133 Balac_0146 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967602.1 163938 D 580050 CDS YP_002967603.1 241190209 8008134 164817..166208 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; transmembrane transport protein 166208 8008134 Balac_0147 Bifidobacterium animalis subsp. lactis Bl-04 transmembrane transport protein YP_002967603.1 164817 D 580050 CDS YP_002967604.1 241190210 8008135 166619..167671 1 NC_012814.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 167671 8008135 Balac_0148 Bifidobacterium animalis subsp. lactis Bl-04 ketol-acid reductoisomerase YP_002967604.1 166619 D 580050 CDS YP_002967605.1 241190211 8008136 complement(168306..170003) 1 NC_012814.1 sialic acid-specific 9-O-acetylesterase 170003 8008136 Balac_0149 Bifidobacterium animalis subsp. lactis Bl-04 sialic acid-specific 9-O-acetylesterase YP_002967605.1 168306 R 580050 CDS YP_002967606.1 241190212 8008137 complement(170427..171524) 1 NC_012814.1 RnfABCDGE type electron transport complex subunit D 171524 8008137 Balac_0150 Bifidobacterium animalis subsp. lactis Bl-04 RnfABCDGE type electron transport complex subunit D YP_002967606.1 170427 R 580050 CDS YP_002967607.1 241190213 8008138 172048..173430 1 NC_012814.1 COG2723Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; putative beta-glucosidase 173430 8008138 Balac_0151 Bifidobacterium animalis subsp. lactis Bl-04 putative beta-glucosidase YP_002967607.1 172048 D 580050 CDS YP_002967608.1 241190214 8008139 173860..174597 1 NC_012814.1 beta-mannosidase 174597 8008139 Balac_0152 Bifidobacterium animalis subsp. lactis Bl-04 beta-mannosidase YP_002967608.1 173860 D 580050 CDS YP_002967609.1 241190215 8008140 174854..175882 1 NC_012814.1 COG1609 Transcriptional regulators; LacI family transcription regulator 175882 8008140 Balac_0153 Bifidobacterium animalis subsp. lactis Bl-04 LacI family transcription regulator YP_002967609.1 174854 D 580050 CDS YP_002967610.1 241190216 8008141 complement(176166..176801) 1 NC_012814.1 hypothetical protein 176801 8008141 Balac_0154 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967610.1 176166 R 580050 CDS YP_002967611.1 241190217 8008142 complement(176885..177616) 1 NC_012814.1 hypothetical protein 177616 8008142 Balac_0155 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967611.1 176885 R 580050 CDS YP_002967612.1 241190218 8008143 177915..178076 1 NC_012814.1 hypothetical protein 178076 8008143 Balac_0156 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967612.1 177915 D 580050 CDS YP_002967613.1 241190219 8008144 178390..179655 1 NC_012814.1 COG2942 N-acyl-D-glucosamine 2-epimerase; hypothetical protein 179655 8008144 Balac_0157 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967613.1 178390 D 580050 CDS YP_002967614.1 241190220 8008145 180183..180923 1 NC_012814.1 COG4619 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATP-binding protein 180923 8008145 Balac_0158 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002967614.1 180183 D 580050 CDS YP_002967615.1 241190221 8008146 180925..181791 1 NC_012814.1 COG0390 ABC-type uncharacterized transport system, permease component; hypothetical protein 181791 8008146 Balac_0159 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967615.1 180925 D 580050 CDS YP_002967616.1 241190222 8008147 181944..183440 1 NC_012814.1 COG1113 Gamma-aminobutyrate permease and related permeases; aromatic amino acid transport protein AroP 183440 8008147 Balac_0160 Bifidobacterium animalis subsp. lactis Bl-04 aromatic amino acid transport protein AroP YP_002967616.1 181944 D 580050 CDS YP_002967617.1 241190223 8008148 184022..184723 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 184723 8008148 Balac_0161 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002967617.1 184022 D 580050 CDS YP_002967618.1 241190224 8008149 184734..187688 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 187688 8008149 Balac_0162 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967618.1 184734 D 580050 CDS YP_002967619.1 241190225 8008150 187743..189287 1 NC_012814.1 COG1113 Gamma-aminobutyrate permease and related permeases; amino acid permease 189287 8008150 Balac_0163 Bifidobacterium animalis subsp. lactis Bl-04 amino acid permease YP_002967619.1 187743 D 580050 CDS YP_002967620.1 241190226 8008151 complement(189299..189544) 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein 189544 8008151 Balac_0164 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter integral membrane protein YP_002967620.1 189299 R 580050 CDS YP_002967621.1 241190227 8008152 complement(189541..189978) 1 NC_012814.1 putative ABC transporter integral membrane protein 189978 8008152 Balac_0165 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter integral membrane protein YP_002967621.1 189541 R 580050 CDS YP_002967622.1 241190228 8008153 complement(189896..191617) 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein 191617 8008153 Balac_0166 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter integral membrane protein YP_002967622.1 189896 R 580050 CDS YP_002967623.1 241190229 8008154 complement(191614..192036) 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 192036 8008154 Balac_0167 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter ATP-binding protein YP_002967623.1 191614 R 580050 CDS YP_002967624.1 241190230 8008155 192731..193324 1 NC_012814.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 193324 8008155 Balac_0168 Bifidobacterium animalis subsp. lactis Bl-04 MarR family transcriptional regulator YP_002967624.1 192731 D 580050 CDS YP_002967625.1 241190231 8008156 193396..195315 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 195315 8008156 Balac_0169 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter ATPase and permease YP_002967625.1 193396 D 580050 CDS YP_002967626.1 241190232 8008157 195387..197222 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease 197222 8008157 Balac_0170 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002967626.1 195387 D 580050 CDS YP_002967627.1 241190233 8008158 complement(197236..198762) 1 NC_012814.1 COG0726 Predicted xylanase/chitin deacetylase; putative secreted polysaccharide deacetylase 198762 8008158 Balac_0171 Bifidobacterium animalis subsp. lactis Bl-04 putative secreted polysaccharide deacetylase YP_002967627.1 197236 R 580050 CDS YP_002967628.1 241190234 8008159 complement(199137..199826) 1 NC_012814.1 COG0671 Membrane-associated phospholipidphosphatase; phosphoesterase PA-phosphatase-like protein 199826 8008159 Balac_0172 Bifidobacterium animalis subsp. lactis Bl-04 phosphoesterase PA-phosphatase-like protein YP_002967628.1 199137 R 580050 CDS YP_002967629.1 241190235 8008160 199902..200537 1 NC_012814.1 COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 200537 8008160 Balac_0173 Bifidobacterium animalis subsp. lactis Bl-04 galactoside O-acetyltransferase YP_002967629.1 199902 D 580050 CDS YP_002967630.1 241190236 8008161 200628..201047 1 NC_012814.1 hypothetical protein 201047 8008161 Balac_0174 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967630.1 200628 D 580050 CDS YP_002967631.1 241190237 8008162 complement(202038..203297) 1 NC_012814.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein 203297 8008162 Balac_0175 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid transport system substrate-binding protein YP_002967631.1 202038 R 580050 CDS YP_002967632.1 241190238 8008163 complement(203888..204541) 1 NC_012814.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 204541 8008163 Balac_0176 Bifidobacterium animalis subsp. lactis Bl-04 TetR family transcriptional regulator YP_002967632.1 203888 R 580050 CDS YP_002967633.1 241190239 8008164 complement(204551..206749) 1 NC_012814.1 COG1511 Predicted membrane protein; putative phage infection protein 206749 8008164 Balac_0177 Bifidobacterium animalis subsp. lactis Bl-04 putative phage infection protein YP_002967633.1 204551 R 580050 CDS YP_002967634.1 241190240 8008165 complement(206746..209514) 1 NC_012814.1 COG1511 Predicted membrane protein; putative phage infection protein 209514 8008165 Balac_0178 Bifidobacterium animalis subsp. lactis Bl-04 putative phage infection protein YP_002967634.1 206746 R 580050 CDS YP_002967635.1 241190241 8008166 209808..210449 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 210449 8008166 Balac_0179 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967635.1 209808 D 580050 CDS YP_002967636.1 241190242 8008167 210446..211186 1 NC_012814.1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease 211186 8008167 Balac_0180 Bifidobacterium animalis subsp. lactis Bl-04 cobalt ABC transporter permease YP_002967636.1 210446 D 580050 CDS YP_002967637.1 241190243 8008168 211239..212726 1 NC_012814.1 COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 212726 8008168 Balac_0181 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002967637.1 211239 D 580050 CDS YP_002967638.1 241190244 8008169 complement(212776..214359) 1 NC_012814.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; hypothetical protein 214359 8008169 Balac_0182 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967638.1 212776 R 580050 CDS YP_002967639.1 241190245 8008170 complement(214555..215436) 1 NC_012814.1 COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein 215436 8008170 Balac_0183 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967639.1 214555 R 580050 CDS YP_002967640.1 241190246 8008171 215572..216339 1 NC_012814.1 COG1309 Transcriptional regulator; hypothetical protein 216339 8008171 Balac_0184 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967640.1 215572 D 580050 CDS YP_002967641.1 241190247 8008172 complement(216519..217229) 1 NC_012814.1 hypothetical protein 217229 8008172 Balac_0185 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967641.1 216519 R 580050 CDS YP_002967642.1 241190248 8009562 217560..219128 1 NC_012814.1 COG4690 Dipeptidase; dipeptidase 219128 8009562 Balac_0187 Bifidobacterium animalis subsp. lactis Bl-04 dipeptidase YP_002967642.1 217560 D 580050 CDS YP_002967643.1 241190249 8008174 complement(219314..220027) 1 NC_012814.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 220027 8008174 Balac_0188 Bifidobacterium animalis subsp. lactis Bl-04 TetR family transcriptional regulator YP_002967643.1 219314 R 580050 CDS YP_002967644.1 241190250 8008175 220154..221554 1 NC_012814.1 COG0552 Signal recognition particle GTPase; FtsY signal recognition particle 221554 8008175 Balac_0189 Bifidobacterium animalis subsp. lactis Bl-04 FtsY signal recognition particle YP_002967644.1 220154 D 580050 CDS YP_002967645.1 241190251 8008176 221814..223109 1 NC_012814.1 COG0004 Ammonia permease; ammonium transporter 223109 8008176 Balac_0190 Bifidobacterium animalis subsp. lactis Bl-04 ammonium transporter YP_002967645.1 221814 D 580050 CDS YP_002967646.1 241190252 8008177 223111..223449 1 NC_012814.1 COG0347 Nitrogen regulatory protein PII; nitrogen regulatory protein N-II 223449 8008177 Balac_0191 Bifidobacterium animalis subsp. lactis Bl-04 nitrogen regulatory protein N-II YP_002967646.1 223111 D 580050 CDS YP_002967647.1 241190253 8008178 223760..225586 1 NC_012814.1 COG2844 UTP:GlnB (protein PII uridylyl transferase); protein-PII uridylyltransferase 225586 8008178 Balac_0192 Bifidobacterium animalis subsp. lactis Bl-04 protein-PII uridylyltransferase YP_002967647.1 223760 D 580050 CDS YP_002967648.1 241190254 8008179 225947..226219 1 NC_012814.1 COG1476 Predicted transcriptional regulators; putative transcriptional regulator 226219 8008179 Balac_0193 Bifidobacterium animalis subsp. lactis Bl-04 putative transcriptional regulator YP_002967648.1 225947 D 580050 CDS YP_002967649.1 241190255 8008180 226278..227657 1 NC_012814.1 COG0305 Replicative DNA helicase; replicative DNA helicase 227657 8008180 Balac_0194 Bifidobacterium animalis subsp. lactis Bl-04 replicative DNA helicase YP_002967649.1 226278 D 580050 CDS YP_002967650.1 241190256 8008181 227754..229262 1 NC_012814.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 229262 8008181 Balac_0195 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylmuramyl tripeptide synthase YP_002967650.1 227754 D 580050 CDS YP_002967651.1 241190257 8008182 229331..230080 1 NC_012814.1 COG3442 Predicted glutamine amidotransferase; cobyric acid synthase CobQ 230080 8008182 Balac_0196 Bifidobacterium animalis subsp. lactis Bl-04 cobyric acid synthase CobQ YP_002967651.1 229331 D 580050 CDS YP_002967652.1 241190258 8008183 230188..230535 1 NC_012814.1 COG3937 Uncharacterized conserved protein; hypothetical protein 230535 8008183 Balac_0197 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967652.1 230188 D 580050 CDS YP_002967653.1 241190259 8008184 230644..232794 1 NC_012814.1 COG0661 Predicted unusual protein kinase; Unusual protein kinase 232794 8008184 Balac_0198 Bifidobacterium animalis subsp. lactis Bl-04 Unusual protein kinase YP_002967653.1 230644 D 580050 CDS YP_002967654.1 241190260 8008185 232905..233942 1 NC_012814.1 COG0584 Glycerophosphoryl diesterphosphodiesterase; phosphodiesterase 233942 8008185 Balac_0199 Bifidobacterium animalis subsp. lactis Bl-04 phosphodiesterase YP_002967654.1 232905 D 580050 CDS YP_002967655.1 241190261 8008186 complement(234038..234679) 1 NC_012814.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 234679 upp 8008186 upp Bifidobacterium animalis subsp. lactis Bl-04 uracil phosphoribosyltransferase YP_002967655.1 234038 R 580050 CDS YP_002967656.1 241190262 8008187 complement(235105..235830) 1 NC_012814.1 hypothetical protein 235830 8008187 Balac_0201 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967656.1 235105 R 580050 CDS YP_002967657.1 241190263 8008188 complement(235835..236878) 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; MutT1 protein 236878 8008188 Balac_0202 Bifidobacterium animalis subsp. lactis Bl-04 MutT1 protein YP_002967657.1 235835 R 580050 CDS YP_002967658.1 241190264 8008189 complement(237015..239249) 1 NC_012814.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 239249 8008189 Balac_0203 Bifidobacterium animalis subsp. lactis Bl-04 polyphosphate kinase YP_002967658.1 237015 R 580050 CDS YP_002967659.1 241190265 8008190 240137..241150 1 NC_012814.1 hypothetical protein 241150 8008190 Balac_0204 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967659.1 240137 D 580050 CDS YP_002967660.1 241190266 8008191 241147..242355 1 NC_012814.1 COG4962 Flp pilus assembly protein, ATPase CpaF; Flp pilus assembly ABC transporter ATPase 242355 8008191 Balac_0205 Bifidobacterium animalis subsp. lactis Bl-04 Flp pilus assembly ABC transporter ATPase YP_002967660.1 241147 D 580050 CDS YP_002967661.1 241190267 8008192 242361..243095 1 NC_012814.1 COG4965 Flp pilus assembly protein TadB; Flp pilus assembly protein 243095 8008192 Balac_0206 Bifidobacterium animalis subsp. lactis Bl-04 Flp pilus assembly protein YP_002967661.1 242361 D 580050 CDS YP_002967662.1 241190268 8008193 243193..243729 1 NC_012814.1 Flp pilus assembly protein 243729 8008193 Balac_0207 Bifidobacterium animalis subsp. lactis Bl-04 Flp pilus assembly protein YP_002967662.1 243193 D 580050 CDS YP_002967663.1 241190269 8008194 243906..244181 1 NC_012814.1 hypothetical protein 244181 8008194 Balac_0208 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967663.1 243906 D 580050 CDS YP_002967664.1 241190270 8008195 244186..244569 1 NC_012814.1 hypothetical protein 244569 8008195 Balac_0209 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967664.1 244186 D 580050 CDS YP_002967665.1 241190271 8008196 244616..245056 1 NC_012814.1 hypothetical protein 245056 8008196 Balac_0210 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967665.1 244616 D 580050 CDS YP_002967666.1 241190272 8008197 245205..247757 1 NC_012814.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 247757 8008197 Balac_0211 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunits gamma and tau YP_002967666.1 245205 D 580050 CDS YP_002967667.1 241190273 8008198 247788..248390 1 NC_012814.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 248390 recR 8008198 recR Bifidobacterium animalis subsp. lactis Bl-04 recombination protein RecR YP_002967667.1 247788 D 580050 CDS YP_002967668.1 241190274 8008199 248511..249275 1 NC_012814.1 COG0527 Aspartokinases; aspartokinase 249275 8008199 Balac_0213 Bifidobacterium animalis subsp. lactis Bl-04 aspartokinase YP_002967668.1 248511 D 580050 CDS YP_002967669.1 241190275 8008200 249348..249914 1 NC_012814.1 COG0527 Aspartokinases; aspartokinase 249914 8008200 Balac_0214 Bifidobacterium animalis subsp. lactis Bl-04 aspartokinase YP_002967669.1 249348 D 580050 CDS YP_002967670.1 241190276 8008201 249971..251041 1 NC_012814.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 251041 8008201 Balac_0215 Bifidobacterium animalis subsp. lactis Bl-04 aspartate-semialdehyde dehydrogenase YP_002967670.1 249971 D 580050 CDS YP_002967671.1 241190277 8008202 251226..251849 1 NC_012814.1 hypothetical protein 251849 8008202 Balac_0216 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967671.1 251226 D 580050 CDS YP_002967672.1 241190278 8008203 252414..254327 1 NC_012814.1 COG0119 Isopropylmalate/homocitrate/citramalatesynthases; 2-isopropylmalate synthase 254327 8008203 Balac_0217 Bifidobacterium animalis subsp. lactis Bl-04 2-isopropylmalate synthase YP_002967672.1 252414 D 580050 CDS YP_002967673.1 241190279 8008204 complement(254475..256883) 1 NC_012814.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); penicillin-binding protein 256883 8008204 Balac_0218 Bifidobacterium animalis subsp. lactis Bl-04 penicillin-binding protein YP_002967673.1 254475 R 580050 CDS YP_002967674.1 241190280 8008205 257185..258327 1 NC_012814.1 COG1260 Myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase 258327 8008205 Balac_0219 Bifidobacterium animalis subsp. lactis Bl-04 myo-inositol-1-phosphate synthase YP_002967674.1 257185 D 580050 CDS YP_002967675.1 241190281 8008206 258722..259942 1 NC_012814.1 pre-pilin peptidase 259942 8008206 Balac_0220 Bifidobacterium animalis subsp. lactis Bl-04 pre-pilin peptidase YP_002967675.1 258722 D 580050 CDS YP_002967676.1 241190282 8008207 260287..263247 1 NC_012814.1 COG0550 Topoisomerase IA; DNA topoisomerase I 263247 8008207 Balac_0221 Bifidobacterium animalis subsp. lactis Bl-04 DNA topoisomerase I YP_002967676.1 260287 D 580050 CDS YP_002967677.1 241190283 8008208 263931..264551 1 NC_012814.1 COG0125 Thymidylate kinase; Thymidylate kinase 264551 8008208 Balac_0222 Bifidobacterium animalis subsp. lactis Bl-04 Thymidylate kinase YP_002967677.1 263931 D 580050 CDS YP_002967678.1 241190284 8008209 264557..265849 1 NC_012814.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 265849 8008209 Balac_0223 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunit delta' YP_002967678.1 264557 D 580050 CDS YP_002967679.1 241190285 8008210 265872..266576 1 NC_012814.1 COG1881 Phospholipid-binding protein; hypothetical protein 266576 8008210 Balac_0224 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967679.1 265872 D 580050 CDS YP_002967680.1 241190286 8008211 267249..268862 1 NC_012814.1 COG4690 Dipeptidase; Dipeptidase 268862 8008211 Balac_0225 Bifidobacterium animalis subsp. lactis Bl-04 Dipeptidase YP_002967680.1 267249 D 580050 CDS YP_002967681.1 241190287 8008212 269382..271007 1 NC_012814.1 COG4690 Dipeptidase; dipeptidase 271007 8008212 Balac_0226 Bifidobacterium animalis subsp. lactis Bl-04 dipeptidase YP_002967681.1 269382 D 580050 CDS YP_002967682.1 241190288 8008213 271358..272527 1 NC_012814.1 COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 272527 8008213 Balac_0227 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967682.1 271358 D 580050 CDS YP_002967683.1 241190289 8008214 272634..274151 1 NC_012814.1 COG2759 Formyltetrahydrofolate synthetase; formate-tetrahydrofolate ligase 274151 8008214 Balac_0228 Bifidobacterium animalis subsp. lactis Bl-04 formate-tetrahydrofolate ligase YP_002967683.1 272634 D 580050 CDS YP_002967684.1 241190290 8008215 complement(274266..274613) 1 NC_012814.1 COG1049 Aconitase B; hypothetical protein 274613 8008215 Balac_0229 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967684.1 274266 R 580050 CDS YP_002967685.1 241190291 8008216 275238..276224 1 NC_012814.1 hypothetical protein 276224 8008216 Balac_0230 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967685.1 275238 D 580050 CDS YP_002967686.1 241190292 8008217 complement(276242..276799) 1 NC_012814.1 COG2246 Predicted membrane protein; hypothetical protein 276799 8008217 Balac_0231 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967686.1 276242 R 580050 CDS YP_002967687.1 241190293 8008218 complement(277025..277969) 1 NC_012814.1 hypothetical protein 277969 8008218 Balac_0232 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967687.1 277025 R 580050 CDS YP_002967688.1 241190294 8008219 complement(278502..279161) 1 NC_012814.1 COG0406 Fructose-2,6-bisphosphatase; hypothetical protein 279161 8008219 Balac_0233 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967688.1 278502 R 580050 CDS YP_002967689.1 241190295 8008220 279568..280986 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 280986 8008220 Balac_0234 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967689.1 279568 D 580050 CDS YP_002967690.1 241190296 8008221 complement(281393..282526) 1 NC_012814.1 COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 282526 8008221 Balac_0235 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS204/IS1001/IS1096/IS1165 family protein YP_002967690.1 281393 R 580050 CDS YP_002967691.1 241190297 8008222 282863..284380 1 NC_012814.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 284380 gltX 8008222 gltX Bifidobacterium animalis subsp. lactis Bl-04 glutamyl-tRNA synthetase YP_002967691.1 282863 D 580050 CDS YP_002967692.1 241190298 8009564 285047..286303 1 NC_012814.1 COG1409 Predicted phosphohydrolases; hypothetical protein 286303 8009564 Balac_0239 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967692.1 285047 D 580050 CDS YP_002967693.1 241190299 8008224 complement(287069..287887) 1 NC_012814.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 287887 8008224 Balac_0240 Bifidobacterium animalis subsp. lactis Bl-04 IclR family transcriptional regulator YP_002967693.1 287069 R 580050 CDS YP_002967694.1 241190300 8008225 288189..289586 1 NC_012814.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 289586 8008225 Balac_0241 Bifidobacterium animalis subsp. lactis Bl-04 isopropylmalate isomerase large subunit YP_002967694.1 288189 D 580050 CDS YP_002967695.1 241190301 8008226 289624..290304 1 NC_012814.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 290304 leuD 8008226 leuD Bifidobacterium animalis subsp. lactis Bl-04 isopropylmalate isomerase small subunit YP_002967695.1 289624 D 580050 CDS YP_002967696.1 241190302 8008227 290559..290837 1 NC_012814.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 290837 8008227 Balac_0243 Bifidobacterium animalis subsp. lactis Bl-04 AsnC family transcriptional regulator YP_002967696.1 290559 D 580050 CDS YP_002967697.1 241190303 8008228 complement(291749..293095) 1 NC_012814.1 COG0446 Uncharacterized NAD (FAD-dependent dehydrogenases); NADH oxidase 293095 8008228 Balac_0244 Bifidobacterium animalis subsp. lactis Bl-04 NADH oxidase YP_002967697.1 291749 R 580050 CDS YP_002967698.1 241190304 8008229 293349..294677 1 NC_012814.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 294677 8008229 Balac_0245 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002967698.1 293349 D 580050 CDS YP_002967699.1 241190305 8008230 295175..296164 1 NC_012814.1 COG0204 1-acyl-sn-glycerol-3-phosphateacyltransferase; hypothetical protein 296164 8008230 Balac_0246 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967699.1 295175 D 580050 CDS YP_002967700.1 241190306 8008231 296520..297518 1 NC_012814.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 297518 gpsA 8008231 gpsA Bifidobacterium animalis subsp. lactis Bl-04 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002967700.1 296520 D 580050 CDS YP_002967701.1 241190307 8008232 297880..299016 1 NC_012814.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 299016 ddl 8008232 ddl Bifidobacterium animalis subsp. lactis Bl-04 D-alanyl-alanine synthetase A YP_002967701.1 297880 D 580050 CDS YP_002967702.1 241190308 8008233 299282..300418 1 NC_012814.1 hypothetical protein 300418 8008233 Balac_0249 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967702.1 299282 D 580050 CDS YP_002967703.1 241190309 8008234 300654..301769 1 NC_012814.1 COG1266 Predicted metal-dependent membrane protease; hypothetical protein 301769 8008234 Balac_0250 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967703.1 300654 D 580050 CDS YP_002967704.1 241190310 8008235 complement(301753..302568) 1 NC_012814.1 COG0668 Small-conductance mechanosensitive channel; hypothetical protein 302568 8008235 Balac_0251 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967704.1 301753 R 580050 CDS YP_002967705.1 241190311 8008236 complement(302625..303194) 1 NC_012814.1 COG1309 Transcriptional regulator; AcrR family transcriptional regulator 303194 8008236 Balac_0252 Bifidobacterium animalis subsp. lactis Bl-04 AcrR family transcriptional regulator YP_002967705.1 302625 R 580050 CDS YP_002967706.1 241190312 8008237 complement(303416..304612) 1 NC_012814.1 hypothetical protein 304612 8008237 Balac_0253 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967706.1 303416 R 580050 CDS YP_002967707.1 241190313 8008238 304727..305593 1 NC_012814.1 COG4905 Predicted membrane protein; hypothetical protein 305593 8008238 Balac_0254 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967707.1 304727 D 580050 CDS YP_002967708.1 241190314 8008239 305657..306853 1 NC_012814.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 306853 8008239 Balac_0255 Bifidobacterium animalis subsp. lactis Bl-04 aspartate aminotransferase YP_002967708.1 305657 D 580050 CDS YP_002967709.1 241190315 8008240 complement(307108..309966) 1 NC_012814.1 hypothetical protein 309966 8008240 Balac_0256 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967709.1 307108 R 580050 CDS YP_002967710.1 241190316 8008241 310344..311996 1 NC_012814.1 COG0457 FOG: TPR repeat; hypothetical protein 311996 8008241 Balac_0257 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967710.1 310344 D 580050 CDS YP_002967711.1 241190317 8008242 complement(312003..313058) 1 NC_012814.1 COG0524 Sugar kinases, ribokinase family; Ribokinase family sugar kinase 313058 8008242 Balac_0258 Bifidobacterium animalis subsp. lactis Bl-04 Ribokinase family sugar kinase YP_002967711.1 312003 R 580050 CDS YP_002967712.1 241190318 8008243 313340..313519 1 NC_012814.1 required for 70S ribosome assembly; 50S ribosomal protein L28 313519 rpmB 8008243 rpmB Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L28 YP_002967712.1 313340 D 580050 CDS YP_002967713.1 241190319 8008244 313760..316132 1 NC_012814.1 COG1200 RecG-like helicase; RecG-like helicase 316132 8008244 Balac_0260 Bifidobacterium animalis subsp. lactis Bl-04 RecG-like helicase YP_002967713.1 313760 D 580050 CDS YP_002967714.1 241190320 8008245 316614..324704 1 NC_012814.1 hypothetical protein 324704 fbp 8008245 fbp Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967714.1 316614 D 580050 CDS YP_002967715.1 241190321 8008246 324931..325056 1 NC_012814.1 hypothetical protein 325056 8008246 Balac_0262 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967715.1 324931 D 580050 CDS YP_002967716.1 241190322 8008247 325353..325928 1 NC_012814.1 COG0742 N6-adenine-specific methylase; hypothetical protein 325928 8008247 Balac_0263 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967716.1 325353 D 580050 CDS YP_002967717.1 241190323 8008248 complement(325955..326782) 1 NC_012814.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 326782 trmD 8008248 trmD Bifidobacterium animalis subsp. lactis Bl-04 tRNA (guanine-N(1)-)-methyltransferase YP_002967717.1 325955 R 580050 CDS YP_002967718.1 241190324 8008249 complement(326938..327597) 1 NC_012814.1 COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM 327597 8008249 Balac_0265 Bifidobacterium animalis subsp. lactis Bl-04 16S rRNA-processing protein RimM YP_002967718.1 326938 R 580050 CDS YP_002967719.1 241190325 8008250 complement(327594..327827) 1 NC_012814.1 COG1837 Predicted RNA-binding protein (contains KH domain); hypothetical protein 327827 8008250 Balac_0266 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967719.1 327594 R 580050 CDS YP_002967720.1 241190326 8008251 complement(327832..328302) 1 NC_012814.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 328302 rpsP 8008251 rpsP Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S16 YP_002967720.1 327832 R 580050 CDS YP_002967721.1 241190327 8008252 328532..331990 1 NC_012814.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-galactosidase 331990 8008252 Balac_0268 Bifidobacterium animalis subsp. lactis Bl-04 beta-galactosidase YP_002967721.1 328532 D 580050 CDS YP_002967722.1 241190328 8008253 complement(332270..333439) 1 NC_012814.1 COG3568 Metal-dependent hydrolase; hypothetical protein 333439 8008253 Balac_0269 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967722.1 332270 R 580050 CDS YP_002967723.1 241190329 8008254 complement(333902..334900) 1 NC_012814.1 COG0053 Predicted Co/Zn/Cd cation transporters; putative Co/Zn/Cd cation transporter 334900 8008254 Balac_0270 Bifidobacterium animalis subsp. lactis Bl-04 putative Co/Zn/Cd cation transporter YP_002967723.1 333902 R 580050 CDS YP_002967724.1 241190330 8008255 334935..336578 1 NC_012814.1 COG0541 Signal recognition particle GTPase; signal recognition particle protein 336578 8008255 Balac_0271 Bifidobacterium animalis subsp. lactis Bl-04 signal recognition particle protein YP_002967724.1 334935 D 580050 CDS YP_002967725.1 241190331 8008256 complement(337722..339359) 1 NC_012814.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 339359 cysS 8008256 cysS Bifidobacterium animalis subsp. lactis Bl-04 cysteinyl-tRNA synthetase YP_002967725.1 337722 R 580050 CDS YP_002967726.1 241190332 8008257 complement(339408..341609) 1 NC_012814.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 341609 8008257 Balac_0273 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATPase YP_002967726.1 339408 R 580050 CDS YP_002967727.1 241190333 8008258 complement(341775..342512) 1 NC_012814.1 COG0518 GMP synthase - Glutamine amidotransferase domain; amidotransferase 342512 8008258 Balac_0274 Bifidobacterium animalis subsp. lactis Bl-04 amidotransferase YP_002967727.1 341775 R 580050 CDS YP_002967728.1 241190334 8008259 complement(342689..343243) 1 NC_012814.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 343243 ilvH 8008259 ilvH Bifidobacterium animalis subsp. lactis Bl-04 acetolactate synthase 3 regulatory subunit YP_002967728.1 342689 R 580050 CDS YP_002967729.1 241190335 8008260 complement(343259..345187) 1 NC_012814.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 345187 8008260 Balac_0276 Bifidobacterium animalis subsp. lactis Bl-04 acetolactate synthase 1 catalytic subunit YP_002967729.1 343259 R 580050 CDS YP_002967730.1 241190336 8008261 complement(345563..346339) 1 NC_012814.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 346339 rnc 8008261 rnc Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease III YP_002967730.1 345563 R 580050 CDS YP_002967731.1 241190337 8008262 complement(346664..346858) 1 NC_012814.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 346858 rpmF 8008262 rpmF Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L32 YP_002967731.1 346664 R 580050 CDS YP_002967732.1 241190338 8008263 complement(346937..347533) 1 NC_012814.1 COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; putative metal-binding/nucleic acid-binding protein 347533 8008263 Balac_0279 Bifidobacterium animalis subsp. lactis Bl-04 putative metal-binding/nucleic acid-binding protein YP_002967732.1 346937 R 580050 CDS YP_002967733.1 241190339 8008264 complement(347618..348319) 1 NC_012814.1 COG3599 Cell division initiation protein; hypothetical protein 348319 8008264 Balac_0280 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967733.1 347618 R 580050 CDS YP_002967734.1 241190340 8008265 complement(348370..348849) 1 NC_012814.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 348849 coaD 8008265 coaD Bifidobacterium animalis subsp. lactis Bl-04 phosphopantetheine adenylyltransferase YP_002967734.1 348370 R 580050 CDS YP_002967735.1 241190341 8008266 349025..349318 1 NC_012814.1 hypothetical protein 349318 8008266 Balac_0282 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967735.1 349025 D 580050 CDS YP_002967736.1 241190342 8008267 complement(349453..350460) 1 NC_012814.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); reductase 350460 8008267 Balac_0283 Bifidobacterium animalis subsp. lactis Bl-04 reductase YP_002967736.1 349453 R 580050 CDS YP_002967737.1 241190343 8008268 complement(350537..351997) 1 NC_012814.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 351997 8008268 Balac_0284 Bifidobacterium animalis subsp. lactis Bl-04 nicotinate phosphoribosyltransferase YP_002967737.1 350537 R 580050 CDS YP_002967738.1 241190344 8008269 352165..352785 1 NC_012814.1 hypothetical protein 352785 8008269 Balac_0285 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967738.1 352165 D 580050 CDS YP_002967739.1 241190345 8008270 353043..353735 1 NC_012814.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 353735 rph 8008270 rph Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease PH YP_002967739.1 353043 D 580050 CDS YP_002967740.1 241190346 8008271 353764..354483 1 NC_012814.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 354483 8008271 Balac_0287 Bifidobacterium animalis subsp. lactis Bl-04 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002967740.1 353764 D 580050 CDS YP_002967741.1 241190347 8008272 354549..355808 1 NC_012814.1 COG2348 Uncharacterized protein involved in methicillin resistance; FemAB-like protein 355808 8008272 Balac_0288 Bifidobacterium animalis subsp. lactis Bl-04 FemAB-like protein YP_002967741.1 354549 D 580050 CDS YP_002967742.1 241190348 8008273 complement(355838..356845) 1 NC_012814.1 COG0679 Predicted permeases; hypothetical protein 356845 8008273 Balac_0289 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967742.1 355838 R 580050 CDS YP_002967743.1 241190349 8009566 357297..358508 1 NC_012814.1 COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanylyltransferase 358508 8009566 Balac_0292 Bifidobacterium animalis subsp. lactis Bl-04 mannose-1-phosphate guanylyltransferase YP_002967743.1 357297 D 580050 CDS YP_002967744.1 241190350 8008275 358798..360495 1 NC_012814.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 360495 pgi 8008275 pgi Bifidobacterium animalis subsp. lactis Bl-04 glucose-6-phosphate isomerase YP_002967744.1 358798 D 580050 CDS YP_002967745.1 241190351 8008276 360819..361184 1 NC_012814.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 361184 rplS 8008276 rplS Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L19 YP_002967745.1 360819 D 580050 CDS YP_002967746.1 241190352 8008277 361398..362123 1 NC_012814.1 COG0681 Signal peptidase I; signal peptidase I 362123 8008277 Balac_0295 Bifidobacterium animalis subsp. lactis Bl-04 signal peptidase I YP_002967746.1 361398 D 580050 CDS YP_002967747.1 241190353 8008278 362168..362944 1 NC_012814.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 362944 rnhB 8008278 rnhB Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease HII YP_002967747.1 362168 D 580050 CDS YP_002967748.1 241190354 8008279 363051..364037 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; SalX-type antimicrobial peptide ABC transporter ATPase 364037 8008279 Balac_0297 Bifidobacterium animalis subsp. lactis Bl-04 SalX-type antimicrobial peptide ABC transporter ATPase YP_002967748.1 363051 D 580050 CDS YP_002967749.1 241190355 8008280 364034..365458 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 365458 8008280 Balac_0298 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002967749.1 364034 D 580050 CDS YP_002967750.1 241190356 8008281 complement(365642..366583) 1 NC_012814.1 COG0679 Predicted permeases; hypothetical protein 366583 8008281 Balac_0299 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967750.1 365642 R 580050 CDS YP_002967751.1 241190357 8008282 366797..368017 1 NC_012814.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 368017 8008282 Balac_0300 Bifidobacterium animalis subsp. lactis Bl-04 succinyl-diaminopimelate desuccinylase YP_002967751.1 366797 D 580050 CDS YP_002967752.1 241190358 8008283 368580..371666 1 NC_012814.1 COG1530 Ribonucleases G and E; ribonuclease G 371666 8008283 Balac_0301 Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease G YP_002967752.1 368580 D 580050 CDS YP_002967753.1 241190359 8008284 372654..372962 1 NC_012814.1 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 372962 rplU 8008284 rplU Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L21 YP_002967753.1 372654 D 580050 CDS YP_002967754.1 241190360 8008285 373002..373253 1 NC_012814.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 373253 rpmA 8008285 rpmA Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L27 YP_002967754.1 373002 D 580050 CDS YP_002967755.1 241190361 8008286 373438..375150 1 NC_012814.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 375150 obgE 8008286 obgE Bifidobacterium animalis subsp. lactis Bl-04 GTPase ObgE YP_002967755.1 373438 D 580050 CDS YP_002967756.1 241190362 8008287 375211..376344 1 NC_012814.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 376344 8008287 Balac_0305 Bifidobacterium animalis subsp. lactis Bl-04 gamma-glutamyl kinase YP_002967756.1 375211 D 580050 CDS YP_002967757.1 241190363 8008288 376458..377675 1 NC_012814.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 377675 8008288 Balac_0306 Bifidobacterium animalis subsp. lactis Bl-04 aspartate aminotransferase YP_002967757.1 376458 D 580050 CDS YP_002967758.1 241190364 8009567 377938..378168 1 NC_012814.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 378168 secE 8009567 secE Bifidobacterium animalis subsp. lactis Bl-04 preprotein translocase subunit SecE YP_002967758.1 377938 D 580050 CDS YP_002967759.1 241190365 8008290 378299..379291 1 NC_012814.1 COG0250 Transcription antiterminator; transcription antiterminator 379291 8008290 Balac_0309 Bifidobacterium animalis subsp. lactis Bl-04 transcription antiterminator YP_002967759.1 378299 D 580050 CDS YP_002967760.1 241190366 8008291 379533..379964 1 NC_012814.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 379964 rplK 8008291 rplK Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L11 YP_002967760.1 379533 D 580050 CDS YP_002967761.1 241190367 8008292 379984..380673 1 NC_012814.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 380673 rplA 8008292 rplA Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L1 YP_002967761.1 379984 D 580050 CDS YP_002967762.1 241190368 8008293 380796..381587 1 NC_012814.1 COG2508 Regulator of polyketide synthase expression; hypothetical protein 381587 8008293 Balac_0312 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967762.1 380796 D 580050 CDS YP_002967763.1 241190369 8008294 381645..382541 1 NC_012814.1 COG0340 Biotin-(acetyl-CoA carboxylase ligase); hypothetical protein 382541 8008294 Balac_0313 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967763.1 381645 D 580050 CDS YP_002967764.1 241190370 8008295 complement(382563..383192) 1 NC_012814.1 COG1268 Uncharacterized conserved protein; hypothetical protein 383192 8008295 Balac_0314 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967764.1 382563 R 580050 CDS YP_002967765.1 241190371 8008296 383488..385362 1 NC_012814.1 COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; JadJ 385362 8008296 Balac_0315 Bifidobacterium animalis subsp. lactis Bl-04 JadJ YP_002967765.1 383488 D 580050 CDS YP_002967766.1 241190372 8008297 385364..386995 1 NC_012814.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); propionyl-CoA carboxylase subunit beta 386995 8008297 Balac_0316 Bifidobacterium animalis subsp. lactis Bl-04 propionyl-CoA carboxylase subunit beta YP_002967766.1 385364 D 580050 CDS YP_002967767.1 241190373 8008298 387129..396446 1 NC_012814.1 COG0331 (acyl-carrier-proteinS-malonyltransferase); fatty acid synthase Fas 396446 8008298 Balac_0317 Bifidobacterium animalis subsp. lactis Bl-04 fatty acid synthase Fas YP_002967767.1 387129 D 580050 CDS YP_002967768.1 241190374 8008299 396679..397125 1 NC_012814.1 COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); holo-ACP synthase 397125 8008299 Balac_0318 Bifidobacterium animalis subsp. lactis Bl-04 holo-ACP synthase YP_002967768.1 396679 D 580050 CDS YP_002967769.1 241190375 8009568 397338..398048 1 NC_012814.1 hypothetical protein 398048 8009568 Balac_0320 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967769.1 397338 D 580050 CDS YP_002967770.1 241190376 8008301 complement(398124..399095) 1 NC_012814.1 COG0039 Malate/lactate dehydrogenases; L-lactate dehydrogenase 399095 8008301 Balac_0321 Bifidobacterium animalis subsp. lactis Bl-04 L-lactate dehydrogenase YP_002967770.1 398124 R 580050 CDS YP_002967771.1 241190377 8008302 399403..399672 1 NC_012814.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 399672 rpsO 8008302 rpsO Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S15 YP_002967771.1 399403 D 580050 CDS YP_002967772.1 241190378 8008303 400014..402635 1 NC_012814.1 COG1185 Polyribonucleotide nucleotidyltransferase(polynucleotide phosphorylase); polynucleotide phosphorylase 402635 8008303 Balac_0323 Bifidobacterium animalis subsp. lactis Bl-04 polynucleotide phosphorylase YP_002967772.1 400014 D 580050 CDS YP_002967773.1 241190379 8008304 402924..403499 1 NC_012814.1 COG1704 Uncharacterized conserved protein; LemA-like protein 403499 8008304 Balac_0324 Bifidobacterium animalis subsp. lactis Bl-04 LemA-like protein YP_002967773.1 402924 D 580050 CDS YP_002967774.1 241190380 8008305 403585..405801 1 NC_012814.1 COG4907 Predicted membrane protein; hypothetical protein 405801 8008305 Balac_0325 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967774.1 403585 D 580050 CDS YP_002967775.1 241190381 8008306 complement(405798..406763) 1 NC_012814.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 406763 nrdF 8008306 nrdF Bifidobacterium animalis subsp. lactis Bl-04 ribonucleotide-diphosphate reductase subunit beta YP_002967775.1 405798 R 580050 CDS YP_002967776.1 241190382 8008307 complement(406803..408899) 1 NC_012814.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 408899 8008307 Balac_0327 Bifidobacterium animalis subsp. lactis Bl-04 ribonucleotide-diphosphate reductase subunit alpha YP_002967776.1 406803 R 580050 CDS YP_002967777.1 241190383 8008308 complement(408939..409364) 1 NC_012814.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 409364 nrdI 8008308 nrdI Bifidobacterium animalis subsp. lactis Bl-04 ribonucleotide reductase stimulatory protein YP_002967777.1 408939 R 580050 CDS YP_002967778.1 241190384 8008309 complement(409361..409624) 1 NC_012814.1 COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein NrdH 409624 8008309 Balac_0329 Bifidobacterium animalis subsp. lactis Bl-04 glutaredoxin-like protein NrdH YP_002967778.1 409361 R 580050 CDS YP_002967779.1 241190385 8008310 409933..410796 1 NC_012814.1 COG0667 Predicted oxidoreductases (related toaryl-alcohol dehydrogenases); aldo/keto reductase 410796 8008310 Balac_0330 Bifidobacterium animalis subsp. lactis Bl-04 aldo/keto reductase YP_002967779.1 409933 D 580050 CDS YP_002967780.1 241190386 8008311 411107..412642 1 NC_012814.1 COG0826 Collagenase and related proteases; protease or peptidase 412642 8008311 Balac_0331 Bifidobacterium animalis subsp. lactis Bl-04 protease or peptidase YP_002967780.1 411107 D 580050 CDS YP_002967781.1 241190387 8008312 412971..414176 1 NC_012814.1 COG1496 Uncharacterized conserved protein; hypothetical protein 414176 8008312 Balac_0332 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967781.1 412971 D 580050 CDS YP_002967782.1 241190388 8008313 414203..415030 1 NC_012814.1 COG1211 4-diphosphocytidyl-2-methyl-D-erithritolsynthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 415030 8008313 Balac_0333 Bifidobacterium animalis subsp. lactis Bl-04 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002967782.1 414203 D 580050 CDS YP_002967783.1 241190389 8008314 414990..415709 1 NC_012814.1 COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase); Pyrrolidone-carboxylate peptidase 415709 8008314 Balac_0334 Bifidobacterium animalis subsp. lactis Bl-04 Pyrrolidone-carboxylate peptidase YP_002967783.1 414990 D 580050 CDS YP_002967784.1 241190390 8008315 415868..417586 1 NC_012814.1 COG3599 Cell division initiation protein; hypothetical protein 417586 8008315 Balac_0335 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967784.1 415868 D 580050 CDS YP_002967785.1 241190391 8008316 417767..419107 1 NC_012814.1 COG3579 Aminopeptidase C; aminopeptidase 419107 8008316 Balac_0336 Bifidobacterium animalis subsp. lactis Bl-04 aminopeptidase YP_002967785.1 417767 D 580050 CDS YP_002967786.1 241190392 8008317 419579..420709 1 NC_012814.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 420709 8008317 Balac_0337 Bifidobacterium animalis subsp. lactis Bl-04 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002967786.1 419579 D 580050 CDS YP_002967787.1 241190393 8008318 420924..422927 1 NC_012814.1 COG1835 Predicted acyltransferases; hypothetical protein 422927 8008318 Balac_0338 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967787.1 420924 D 580050 CDS YP_002967788.1 241190394 8008319 423000..424247 1 NC_012814.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 424247 8008319 Balac_0339 Bifidobacterium animalis subsp. lactis Bl-04 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002967788.1 423000 D 580050 CDS YP_002967789.1 241190395 8008320 424326..425018 1 NC_012814.1 COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine nucleosidase 425018 8008320 Balac_0340 Bifidobacterium animalis subsp. lactis Bl-04 5'-methylthioadenosine nucleosidase YP_002967789.1 424326 D 580050 CDS YP_002967790.1 241190396 8008321 425050..426273 1 NC_012814.1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 426273 8008321 Balac_0341 Bifidobacterium animalis subsp. lactis Bl-04 signal transduction histidine kinase YP_002967790.1 425050 D 580050 CDS YP_002967791.1 241190397 8008322 426270..426977 1 NC_012814.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 426977 8008322 Balac_0342 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002967791.1 426270 D 580050 CDS YP_002967792.1 241190398 8008323 427064..428179 1 NC_012814.1 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 428179 8008323 Balac_0343 Bifidobacterium animalis subsp. lactis Bl-04 phosphate ABC transporter substrate-binding protein YP_002967792.1 427064 D 580050 CDS YP_002967793.1 241190399 8008324 428184..429164 1 NC_012814.1 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 429164 8008324 Balac_0344 Bifidobacterium animalis subsp. lactis Bl-04 phosphate ABC transporter permease YP_002967793.1 428184 D 580050 CDS YP_002967794.1 241190400 8008325 429161..430153 1 NC_012814.1 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter substrate-binding protein 430153 8008325 Balac_0345 Bifidobacterium animalis subsp. lactis Bl-04 phosphate ABC transporter substrate-binding protein YP_002967794.1 429161 D 580050 CDS YP_002967795.1 241190401 8008326 430190..430969 1 NC_012814.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 430969 8008326 Balac_0346 Bifidobacterium animalis subsp. lactis Bl-04 phosphate transporter ATP-binding protein YP_002967795.1 430190 D 580050 CDS YP_002967796.1 241190402 8008327 431261..432601 1 NC_012814.1 COG2252 Permeases; hypothetical protein 432601 8008327 Balac_0347 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967796.1 431261 D 580050 CDS YP_002967797.1 241190403 8008328 complement(432936..433859) 1 NC_012814.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic component 433859 8008328 Balac_0348 Bifidobacterium animalis subsp. lactis Bl-04 metal ion ABC transporter periplasmic component YP_002967797.1 432936 R 580050 CDS YP_002967798.1 241190404 8008329 434212..434733 1 NC_012814.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 434733 rplJ 8008329 rplJ Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L10 YP_002967798.1 434212 D 580050 CDS YP_002967799.1 241190405 8008330 434844..435224 1 NC_012814.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 435224 rplL 8008330 rplL Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L7/L12 YP_002967799.1 434844 D 580050 CDS YP_002967800.1 241190406 8008331 435507..437081 1 NC_012814.1 COG1716 FOG: FHA domain; Tfp pilus assembly protein 437081 8008331 Balac_0351 Bifidobacterium animalis subsp. lactis Bl-04 Tfp pilus assembly protein YP_002967800.1 435507 D 580050 CDS YP_002967801.1 241190407 8008332 437078..440725 1 NC_012814.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 440725 8008332 Balac_0352 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967801.1 437078 D 580050 CDS YP_002967802.1 241190408 8008333 440760..441002 1 NC_012814.1 hypothetical protein 441002 8008333 Balac_0353 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967802.1 440760 D 580050 CDS YP_002967803.1 241190409 8008334 complement(441021..441578) 1 NC_012814.1 hypothetical protein 441578 8008334 Balac_0354 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967803.1 441021 R 580050 CDS YP_002967804.1 241190410 8008335 complement(441817..442008) 1 NC_012814.1 COG2331 Uncharacterized protein conserved in bacteria; hypothetical protein 442008 8008335 Balac_0355 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967804.1 441817 R 580050 CDS YP_002967805.1 241190411 8008336 complement(442140..442877) 1 NC_012814.1 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 442877 8008336 Balac_0356 Bifidobacterium animalis subsp. lactis Bl-04 5-formyltetrahydrofolate cyclo-ligase YP_002967805.1 442140 R 580050 CDS YP_002967806.1 241190412 8008337 443034..443717 1 NC_012814.1 COG1670 Acetyltransferases, including N-acetylasesof ribosomal proteins; acetytransferase 443717 8008337 Balac_0357 Bifidobacterium animalis subsp. lactis Bl-04 acetytransferase YP_002967806.1 443034 D 580050 CDS YP_002967807.1 241190413 8008338 443739..444962 1 NC_012814.1 hypothetical protein 444962 8008338 Balac_0358 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967807.1 443739 D 580050 CDS YP_002967808.1 241190414 8008339 445184..445480 1 NC_012814.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 445480 groES 8008339 groES Bifidobacterium animalis subsp. lactis Bl-04 co-chaperonin GroES YP_002967808.1 445184 D 580050 CDS YP_002967809.1 241190415 8009571 446149..446319 1 NC_012814.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 446319 rpmG 8009571 rpmG Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L33 YP_002967809.1 446149 D 580050 CDS YP_002967810.1 241190416 8008341 446413..447633 1 NC_012814.1 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase 447633 8008341 Balac_0364 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002967810.1 446413 D 580050 CDS YP_002967811.1 241190417 8008342 448005..449507 1 NC_012814.1 COG0531 Amino acid transporters; Amino acid transporter 449507 8008342 Balac_0365 Bifidobacterium animalis subsp. lactis Bl-04 Amino acid transporter YP_002967811.1 448005 D 580050 CDS YP_002967812.1 241190418 8008343 449673..449996 1 NC_012814.1 COG1146 Ferredoxin; ferredoxin 449996 8008343 Balac_0366 Bifidobacterium animalis subsp. lactis Bl-04 ferredoxin YP_002967812.1 449673 D 580050 CDS YP_002967813.1 241190419 8008344 450091..451248 1 NC_012814.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 451248 8008344 Balac_0367 Bifidobacterium animalis subsp. lactis Bl-04 N-succinyldiaminopimelate aminotransferase YP_002967813.1 450091 D 580050 CDS YP_002967814.1 241190420 8008345 complement(451286..452602) 1 NC_012814.1 COG0389 Nucleotidyltransferase/DNA polymeraseinvolved in DNA repair; DNA-damage-inducible protein P 452602 8008345 Balac_0368 Bifidobacterium animalis subsp. lactis Bl-04 DNA-damage-inducible protein P YP_002967814.1 451286 R 580050 CDS YP_002967815.1 241190421 8009572 453222..454229 1 NC_012814.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; 2-hydroxyacid dehydrogenase 454229 8009572 Balac_0370 Bifidobacterium animalis subsp. lactis Bl-04 2-hydroxyacid dehydrogenase YP_002967815.1 453222 D 580050 CDS YP_002967816.1 241190422 8008347 454286..454921 1 NC_012814.1 COG1739 Uncharacterized conserved protein; hypothetical protein 454921 8008347 Balac_0371 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967816.1 454286 D 580050 CDS YP_002967817.1 241190423 8008348 454900..455718 1 NC_012814.1 AbrB family transcriptional regulator 455718 8008348 Balac_0372 Bifidobacterium animalis subsp. lactis Bl-04 AbrB family transcriptional regulator YP_002967817.1 454900 D 580050 CDS YP_002967818.1 241190424 8008349 455827..457995 1 NC_012814.1 COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 457995 8008349 Balac_0373 Bifidobacterium animalis subsp. lactis Bl-04 4-alpha-glucanotransferase YP_002967818.1 455827 D 580050 CDS YP_002967819.1 241190425 8008350 458277..458726 1 NC_012814.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 458726 rplM 8008350 rplM Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L13 YP_002967819.1 458277 D 580050 CDS YP_002967820.1 241190426 8008351 458746..459237 1 NC_012814.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 459237 rpsI 8008351 rpsI Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S9 YP_002967820.1 458746 D 580050 CDS YP_002967821.1 241190427 8008352 complement(459345..462041) 1 NC_012814.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX 462041 8008352 Balac_0376 Bifidobacterium animalis subsp. lactis Bl-04 glycogen operon protein GlgX YP_002967821.1 459345 R 580050 CDS YP_002967822.1 241190428 8008353 complement(462100..463191) 1 NC_012814.1 COG1940 Transcriptional regulator/sugar kinase; Rok family repressor 463191 8008353 Balac_0377 Bifidobacterium animalis subsp. lactis Bl-04 Rok family repressor YP_002967822.1 462100 R 580050 CDS YP_002967823.1 241190429 8008354 463598..466345 1 NC_012814.1 COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 466345 8008354 Balac_0378 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002967823.1 463598 D 580050 CDS YP_002967824.1 241190430 8008355 complement(466661..467635) 1 NC_012814.1 hypothetical protein 467635 8008355 Balac_0379 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967824.1 466661 R 580050 CDS YP_002967825.1 241190431 8008356 467831..468580 1 NC_012814.1 hypothetical protein 468580 8008356 Balac_0380 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967825.1 467831 D 580050 CDS YP_002967826.1 241190432 8008357 468858..469166 1 NC_012814.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 469166 rpsJ 8008357 rpsJ Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S10 YP_002967826.1 468858 D 580050 CDS YP_002967827.1 241190433 8008358 469184..469834 1 NC_012814.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 469834 rplC 8008358 rplC Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L3 YP_002967827.1 469184 D 580050 CDS YP_002967828.1 241190434 8008359 469840..470496 1 NC_012814.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 470496 rplD 8008359 rplD Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L4 YP_002967828.1 469840 D 580050 CDS YP_002967829.1 241190435 8008360 470501..470797 1 NC_012814.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 470797 rplW 8008360 rplW Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L23 YP_002967829.1 470501 D 580050 CDS YP_002967830.1 241190436 8008361 470835..471665 1 NC_012814.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 471665 rplB 8008361 rplB Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L2 YP_002967830.1 470835 D 580050 CDS YP_002967831.1 241190437 8008362 471681..471959 1 NC_012814.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 471959 rpsS 8008362 rpsS Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S19 YP_002967831.1 471681 D 580050 CDS YP_002967832.2 394895231 8008363 471981..472340 1 NC_012814.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 472340 rplV 8008363 rplV Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L22 YP_002967832.2 471981 D 580050 CDS YP_002967833.1 241190439 8008364 472343..473176 1 NC_012814.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 473176 rpsC 8008364 rpsC Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S3 YP_002967833.1 472343 D 580050 CDS YP_002967834.1 241190440 8008365 473184..473603 1 NC_012814.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 473603 rplP 8008365 rplP Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L16 YP_002967834.1 473184 D 580050 CDS YP_002967835.1 241190441 8008366 473603..473851 1 NC_012814.1 COG0255 Ribosomal protein L29; Ribosomal protein L29 473851 8008366 Balac_0390 Bifidobacterium animalis subsp. lactis Bl-04 Ribosomal protein L29 YP_002967835.1 473603 D 580050 CDS YP_002967836.1 241190442 8008367 473861..474121 1 NC_012814.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 474121 rpsQ 8008367 rpsQ Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S17 YP_002967836.1 473861 D 580050 CDS YP_002967837.1 241190443 8008368 474210..474578 1 NC_012814.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 474578 rplN 8008368 rplN Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L14 YP_002967837.1 474210 D 580050 CDS YP_002967838.1 241190444 8008369 474580..474915 1 NC_012814.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 474915 rplX 8008369 rplX Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L24 YP_002967838.1 474580 D 580050 CDS YP_002967839.1 241190445 8008370 474912..475496 1 NC_012814.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 475496 rplE 8008370 rplE Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L5 YP_002967839.1 474912 D 580050 CDS YP_002967840.1 241190446 8008371 475498..475683 1 NC_012814.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 475683 rpsN 8008371 rpsN Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S14 YP_002967840.1 475498 D 580050 CDS YP_002967841.1 241190447 8008372 475771..476169 1 NC_012814.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 476169 rpsH 8008372 rpsH Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S8 YP_002967841.1 475771 D 580050 CDS YP_002967842.1 241190448 8008373 476186..476725 1 NC_012814.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 476725 rplF 8008373 rplF Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L6 YP_002967842.1 476186 D 580050 CDS YP_002967843.1 241190449 8008374 476727..477098 1 NC_012814.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 477098 rplR 8008374 rplR Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L18 YP_002967843.1 476727 D 580050 CDS YP_002967844.1 241190450 8008375 477122..477826 1 NC_012814.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 477826 rpsE 8008375 rpsE Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S5 YP_002967844.1 477122 D 580050 CDS YP_002967845.1 241190451 8008376 477826..478008 1 NC_012814.1 COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 478008 rpmD 8008376 rpmD Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L30 YP_002967845.1 477826 D 580050 CDS YP_002967846.1 241190452 8008377 478011..478469 1 NC_012814.1 late assembly protein; 50S ribosomal protein L15 478469 rplO 8008377 rplO Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L15 YP_002967846.1 478011 D 580050 CDS YP_002967847.1 241190453 8008378 478707..480056 1 NC_012814.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 480056 secY 8008378 secY Bifidobacterium animalis subsp. lactis Bl-04 preprotein translocase subunit SecY YP_002967847.1 478707 D 580050 CDS YP_002967848.1 241190454 8008379 480229..480801 1 NC_012814.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 480801 adk 8008379 adk Bifidobacterium animalis subsp. lactis Bl-04 adenylate kinase YP_002967848.1 480229 D 580050 CDS YP_002967849.1 241190455 8008380 481050..481268 1 NC_012814.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 481268 infA 8008380 infA Bifidobacterium animalis subsp. lactis Bl-04 translation initiation factor IF-1 YP_002967849.1 481050 D 580050 CDS YP_002967850.1 241190456 8008381 481307..481420 1 NC_012814.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 481420 rpmJ 8008381 rpmJ Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L36 YP_002967850.1 481307 D 580050 CDS YP_002967851.1 241190457 8008382 481559..481936 1 NC_012814.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 481936 rpsM 8008382 rpsM Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S13 YP_002967851.1 481559 D 580050 CDS YP_002967852.1 241190458 8008383 482013..482411 1 NC_012814.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 482411 8008383 Balac_0407 Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S11 YP_002967852.1 482013 D 580050 CDS YP_002967853.1 241190459 8008384 482490..483485 1 NC_012814.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 483485 8008384 Balac_0408 Bifidobacterium animalis subsp. lactis Bl-04 DNA-directed RNA polymerase subunit alpha YP_002967853.1 482490 D 580050 CDS YP_002967854.1 241190460 8008385 483570..484016 1 NC_012814.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 484016 rplQ 8008385 rplQ Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L17 YP_002967854.1 483570 D 580050 CDS YP_002967855.1 241190461 8008386 484238..485014 1 NC_012814.1 COG0101 Pseudouridylate synthase; tRNA pseudouridine synthase A 485014 8008386 Balac_0410 Bifidobacterium animalis subsp. lactis Bl-04 tRNA pseudouridine synthase A YP_002967855.1 484238 D 580050 CDS YP_002967856.1 241190462 8009573 complement(485393..486304) 1 NC_012814.1 hypothetical protein 486304 8009573 Balac_0412 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967856.1 485393 R 580050 CDS YP_002967857.1 241190463 8008388 486417..487493 1 NC_012814.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 487493 nusA 8008388 nusA Bifidobacterium animalis subsp. lactis Bl-04 transcription elongation factor NusA YP_002967857.1 486417 D 580050 CDS YP_002967858.1 241190464 8008389 487703..490537 1 NC_012814.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 490537 infB 8008389 infB Bifidobacterium animalis subsp. lactis Bl-04 translation initiation factor IF-2 YP_002967858.1 487703 D 580050 CDS YP_002967859.1 241190465 8008390 490691..491344 1 NC_012814.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 491344 rbfA 8008390 rbfA Bifidobacterium animalis subsp. lactis Bl-04 ribosome-binding factor A YP_002967859.1 490691 D 580050 CDS YP_002967860.1 241190466 8008391 491348..492400 1 NC_012814.1 COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 492400 8008391 Balac_0416 Bifidobacterium animalis subsp. lactis Bl-04 tRNA pseudouridine synthase B YP_002967860.1 491348 D 580050 CDS YP_002967861.1 241190467 8008392 492408..493694 1 NC_012814.1 COG0196 FAD synthase; riboflavin kinase 493694 8008392 Balac_0417 Bifidobacterium animalis subsp. lactis Bl-04 riboflavin kinase YP_002967861.1 492408 D 580050 CDS YP_002967862.1 241190468 8008393 complement(493706..495181) 1 NC_012814.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 495181 8008393 Balac_0418 Bifidobacterium animalis subsp. lactis Bl-04 DNA repair protein RadA YP_002967862.1 493706 R 580050 CDS YP_002967863.1 241190469 8008394 495404..495985 1 NC_012814.1 hypothetical protein 495985 8008394 Balac_0419 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967863.1 495404 D 580050 CDS YP_002967864.1 241190470 8008395 complement(496318..497019) 1 NC_012814.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 497019 8008395 Balac_0420 Bifidobacterium animalis subsp. lactis Bl-04 ribose-5-phosphate isomerase A YP_002967864.1 496318 R 580050 CDS YP_002967865.1 241190471 8008396 complement(497109..498098) 1 NC_012814.1 COG0328 Ribonuclease HI; ribonuclease H 498098 8008396 Balac_0421 Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease H YP_002967865.1 497109 R 580050 CDS YP_002967866.1 241190472 8009574 complement(499326..500612) 1 NC_012814.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 500612 8009574 Balac_0423 Bifidobacterium animalis subsp. lactis Bl-04 seryl-tRNA synthetase YP_002967866.1 499326 R 580050 CDS YP_002967867.1 241190473 8008398 500784..501941 1 NC_012814.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; hypothetical protein 501941 8008398 Balac_0424 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967867.1 500784 D 580050 CDS YP_002967868.1 241190474 8008399 502101..503777 1 NC_012814.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 503777 8008399 Balac_0425 Bifidobacterium animalis subsp. lactis Bl-04 phosphoglucomutase YP_002967868.1 502101 D 580050 CDS YP_002967869.1 241190475 8008400 complement(503899..505458) 1 NC_012814.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 505458 8008400 Balac_0426 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967869.1 503899 R 580050 CDS YP_002967870.1 241190476 8008401 complement(505549..506169) 1 NC_012814.1 hypothetical protein 506169 8008401 Balac_0427 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967870.1 505549 R 580050 CDS YP_002967871.1 241190477 8008402 complement(506199..508331) 1 NC_012814.1 COG0457 FOG: TPR repeat; hypothetical protein 508331 8008402 Balac_0428 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967871.1 506199 R 580050 CDS YP_002967872.1 241190478 8008403 complement(508386..509096) 1 NC_012814.1 COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; two-component system response regulator 509096 8008403 Balac_0429 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002967872.1 508386 R 580050 CDS YP_002967873.1 241190479 8008404 complement(509389..510849) 1 NC_012814.1 COG1983 Putative stress-responsive transcriptional regulator; histidine kinase sensor of two component system 510849 8008404 Balac_0430 Bifidobacterium animalis subsp. lactis Bl-04 histidine kinase sensor of two component system YP_002967873.1 509389 R 580050 CDS YP_002967874.1 241190480 8008405 510963..513050 1 NC_012814.1 COG1983 Putative stress-responsive transcriptional regulator; hypothetical protein 513050 8008405 Balac_0431 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967874.1 510963 D 580050 CDS YP_002967875.1 241190481 8008406 513067..513711 1 NC_012814.1 hypothetical protein 513711 8008406 Balac_0432 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967875.1 513067 D 580050 CDS YP_002967876.1 241190482 8008407 514002..515201 1 NC_012814.1 COG0626 Cystathionine beta-lyases/cystathioninegamma-synthases; cystathionine beta-lyase 515201 8008407 Balac_0433 Bifidobacterium animalis subsp. lactis Bl-04 cystathionine beta-lyase YP_002967876.1 514002 D 580050 CDS YP_002967877.1 241190483 8008408 515248..515949 1 NC_012814.1 COG2873 O-acetylhomoserine sulfhydrylase; cysteine synthase 515949 8008408 Balac_0434 Bifidobacterium animalis subsp. lactis Bl-04 cysteine synthase YP_002967877.1 515248 D 580050 CDS YP_002967878.1 241190484 8008409 515925..516122 1 NC_012814.1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase 516122 8008409 Balac_0435 Bifidobacterium animalis subsp. lactis Bl-04 O-acetylhomoserine sulfhydrylase YP_002967878.1 515925 D 580050 CDS YP_002967879.1 241190485 8009575 516537..518153 1 NC_012814.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 518153 lysS 8009575 lysS Bifidobacterium animalis subsp. lactis Bl-04 lysyl-tRNA synthetase YP_002967879.1 516537 D 580050 CDS YP_002967880.1 241190486 8008411 518304..519365 1 NC_012814.1 hypothetical protein 519365 8008411 Balac_0438 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967880.1 518304 D 580050 CDS YP_002967881.1 241190487 8008412 519670..519783 1 NC_012814.1 hypothetical protein 519783 8008412 Balac_0439 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967881.1 519670 D 580050 CDS YP_002967882.1 241190488 8008413 520131..521486 1 NC_012814.1 hypothetical protein 521486 8008413 Balac_0440 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967882.1 520131 D 580050 CDS YP_002967883.1 241190489 8008414 521697..523055 1 NC_012814.1 COG3579 Aminopeptidase C; aminopeptidase 523055 8008414 Balac_0441 Bifidobacterium animalis subsp. lactis Bl-04 aminopeptidase YP_002967883.1 521697 D 580050 CDS YP_002967884.1 241190490 8008415 523159..525282 1 NC_012814.1 COG0531 Amino acid transporters; hypothetical protein 525282 8008415 Balac_0442 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967884.1 523159 D 580050 CDS YP_002967885.1 241190491 8008416 525400..526893 1 NC_012814.1 COG2939 Carboxypeptidase C (cathepsin A); carboxypeptidase C 526893 8008416 Balac_0443 Bifidobacterium animalis subsp. lactis Bl-04 carboxypeptidase C YP_002967885.1 525400 D 580050 CDS YP_002967886.1 241190492 8008417 527102..528631 1 NC_012814.1 COG0531 Amino acid transporters; amino acid transporter 528631 8008417 Balac_0444 Bifidobacterium animalis subsp. lactis Bl-04 amino acid transporter YP_002967886.1 527102 D 580050 CDS YP_002967887.1 241190493 8008418 528747..529790 1 NC_012814.1 COG1575 1,4-dihydroxy-2-naphthoateoctaprenyl transferase; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 529790 8008418 Balac_0445 Bifidobacterium animalis subsp. lactis Bl-04 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002967887.1 528747 D 580050 CDS YP_002967888.1 241190494 8008419 529888..530628 1 NC_012814.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 530628 gpmA 8008419 gpmA Bifidobacterium animalis subsp. lactis Bl-04 phosphoglyceromutase YP_002967888.1 529888 D 580050 CDS YP_002967889.1 241190495 8008420 531276..533402 1 NC_012814.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 533402 8008420 Balac_0447 Bifidobacterium animalis subsp. lactis Bl-04 myosin-cross-reactive antigen YP_002967889.1 531276 D 580050 CDS YP_002967890.1 241190496 8008421 complement(534589..535959) 1 NC_012814.1 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 535959 8008421 Balac_0448 Bifidobacterium animalis subsp. lactis Bl-04 mannose-6-phosphate isomerase YP_002967890.1 534589 R 580050 CDS YP_002967891.1 241190497 8008422 complement(536294..537682) 1 NC_012814.1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 537682 8008422 Balac_0449 Bifidobacterium animalis subsp. lactis Bl-04 signal transduction histidine kinase YP_002967891.1 536294 R 580050 CDS YP_002967892.1 241190498 8008423 537852..538532 1 NC_012814.1 COG0704 Phosphate uptake regulator; two-component system response regulator 538532 8008423 Balac_0450 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002967892.1 537852 D 580050 CDS YP_002967893.1 241190499 8008424 complement(538689..539801) 1 NC_012814.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 539801 8008424 Balac_0451 Bifidobacterium animalis subsp. lactis Bl-04 phosphoserine aminotransferase YP_002967893.1 538689 R 580050 CDS YP_002967894.1 241190500 8008425 540165..541190 1 NC_012814.1 COG3942 Surface antigen; Surface antigen protein 541190 8008425 Balac_0452 Bifidobacterium animalis subsp. lactis Bl-04 Surface antigen protein YP_002967894.1 540165 D 580050 CDS YP_002967895.1 241190501 8008426 541388..541546 1 NC_012814.1 hypothetical protein 541546 8008426 Balac_0453 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967895.1 541388 D 580050 CDS YP_002967896.1 241190502 8008427 541661..542470 1 NC_012814.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Cell wall-associated hydrolase 542470 8008427 Balac_0454 Bifidobacterium animalis subsp. lactis Bl-04 Cell wall-associated hydrolase YP_002967896.1 541661 D 580050 CDS YP_002967897.1 241190503 8008428 542964..544019 1 NC_012814.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein 544019 8008428 Balac_0455 Bifidobacterium animalis subsp. lactis Bl-04 Universal stress protein YP_002967897.1 542964 D 580050 CDS YP_002967898.1 241190504 8008429 complement(544108..544521) 1 NC_012814.1 COG1765 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 544521 8008429 Balac_0456 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967898.1 544108 R 580050 CDS YP_002967899.1 241190505 8008430 544655..545527 1 NC_012814.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 545527 thyA 8008430 thyA Bifidobacterium animalis subsp. lactis Bl-04 thymidylate synthase YP_002967899.1 544655 D 580050 CDS YP_002967900.1 241190506 8008431 545653..546336 1 NC_012814.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 546336 8008431 Balac_0458 Bifidobacterium animalis subsp. lactis Bl-04 dihydrofolate reductase YP_002967900.1 545653 D 580050 CDS YP_002967901.1 241190507 8008432 546371..546907 1 NC_012814.1 COG0394 Protein-tyrosine-phosphatase; low molecular weight protein-tyrosine-phosphatase 546907 8008432 Balac_0459 Bifidobacterium animalis subsp. lactis Bl-04 low molecular weight protein-tyrosine-phosphatase YP_002967901.1 546371 D 580050 CDS YP_002967902.1 241190508 8008433 complement(547006..548016) 1 NC_012814.1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 548016 8008433 Balac_0460 Bifidobacterium animalis subsp. lactis Bl-04 UDP-glucose 4-epimerase YP_002967902.1 547006 R 580050 CDS YP_002967903.1 241190509 8008434 548353..549198 1 NC_012814.1 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA (guanine-N(7--methyltransferase)) 549198 8008434 Balac_0461 Bifidobacterium animalis subsp. lactis Bl-04 tRNA (guanine-N(7--methyltransferase)) YP_002967903.1 548353 D 580050 CDS YP_002967904.1 241190510 8009576 complement(549808..550875) 1 NC_012814.1 COG1434 Uncharacterized conserved protein; hypothetical protein 550875 8009576 Balac_0463 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967904.1 549808 R 580050 CDS YP_002967905.1 241190511 8008436 551022..552017 1 NC_012814.1 putative 5'-nucleotidase 552017 8008436 Balac_0464 Bifidobacterium animalis subsp. lactis Bl-04 putative 5'-nucleotidase YP_002967905.1 551022 D 580050 CDS YP_002967906.1 241190512 8008437 552271..552696 1 NC_012814.1 COG3642 Mn2+-dependent serine/threonine protein kinase; hypothetical protein 552696 8008437 Balac_0465 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967906.1 552271 D 580050 CDS YP_002967907.1 241190513 8008438 552722..554269 1 NC_012814.1 COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 554269 8008438 Balac_0466 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967907.1 552722 D 580050 CDS YP_002967908.1 241190514 8008439 554403..554765 1 NC_012814.1 hypothetical protein 554765 8008439 Balac_0467 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967908.1 554403 D 580050 CDS YP_002967909.1 241190515 8008440 554756..555559 1 NC_012814.1 cutinase 555559 8008440 Balac_0468 Bifidobacterium animalis subsp. lactis Bl-04 cutinase YP_002967909.1 554756 D 580050 CDS YP_002967910.1 241190516 8008441 555508..556920 1 NC_012814.1 COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein 556920 8008441 Balac_0469 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967910.1 555508 D 580050 CDS YP_002967911.1 241190517 8008442 557034..558608 1 NC_012814.1 hypothetical protein 558608 8008442 Balac_0470 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967911.1 557034 D 580050 CDS YP_002967912.1 241190518 8008443 558610..559419 1 NC_012814.1 hypothetical protein 559419 8008443 Balac_0471 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967912.1 558610 D 580050 CDS YP_002967913.1 241190519 8008444 559416..562913 1 NC_012814.1 COG4913 Uncharacterized protein conserved in bacteria; hypothetical protein 562913 8008444 Balac_0472 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967913.1 559416 D 580050 CDS YP_002967914.1 241190520 8008445 562910..564130 1 NC_012814.1 COG4924 Uncharacterized protein conserved in bacteria; hypothetical protein 564130 8008445 Balac_0473 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967914.1 562910 D 580050 CDS YP_002967915.1 241190521 8008446 complement(564498..564890) 1 NC_012814.1 COG3189 Uncharacterized conserved protein; hypothetical protein 564890 8008446 Balac_0474 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967915.1 564498 R 580050 CDS YP_002967916.1 241190522 8008447 complement(565133..566650) 1 NC_012814.1 COG2211 Na+/melibiose symporter and related transporters; galactoside symporter 566650 lacS 8008447 lacS Bifidobacterium animalis subsp. lactis Bl-04 galactoside symporter YP_002967916.1 565133 R 580050 CDS YP_002967917.1 241190523 8008448 566960..570163 1 NC_012814.1 COG3250 Beta-galactosidase/beta-glucuronidase; LacZ 570163 lacZ 8008448 lacZ Bifidobacterium animalis subsp. lactis Bl-04 LacZ YP_002967917.1 566960 D 580050 CDS YP_002967918.1 241190524 8008449 complement(570266..571261) 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 571261 8008449 Balac_0477 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002967918.1 570266 R 580050 CDS YP_002967919.1 241190525 8008450 571695..572303 1 NC_012814.1 COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase 572303 8008450 Balac_0478 Bifidobacterium animalis subsp. lactis Bl-04 alpha beta hydrolase YP_002967919.1 571695 D 580050 CDS YP_002967920.1 241190526 8008451 complement(572430..572825) 1 NC_012814.1 hypothetical protein 572825 8008451 Balac_0479 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967920.1 572430 R 580050 CDS YP_002967921.1 241190527 8008452 572972..573562 1 NC_012814.1 hypothetical protein 573562 8008452 Balac_0480 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967921.1 572972 D 580050 CDS YP_002967922.1 241190528 8008453 573559..573732 1 NC_012814.1 hypothetical protein 573732 8008453 Balac_0481 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967922.1 573559 D 580050 CDS YP_002967923.1 241190529 8008454 573742..574242 1 NC_012814.1 hypothetical protein 574242 8008454 Balac_0482 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967923.1 573742 D 580050 CDS YP_002967924.1 241190530 8008455 complement(574340..575683) 1 NC_012814.1 COG1653 ABC-type sugar transport system, periplasmic component; MalE-type ABC sugar transport system periplasmic component 575683 8008455 Balac_0483 Bifidobacterium animalis subsp. lactis Bl-04 MalE-type ABC sugar transport system periplasmic component YP_002967924.1 574340 R 580050 CDS YP_002967925.1 241190531 8008456 complement(575929..578016) 1 NC_012814.1 COG1874 Beta-galactosidase; beta-galactosidase 578016 8008456 Balac_0484 Bifidobacterium animalis subsp. lactis Bl-04 beta-galactosidase YP_002967925.1 575929 R 580050 CDS YP_002967926.1 241190532 8008457 complement(578058..579038) 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 579038 8008457 Balac_0485 Bifidobacterium animalis subsp. lactis Bl-04 sugar ABC transporter permease YP_002967926.1 578058 R 580050 CDS YP_002967927.1 241190533 8008458 complement(579058..580026) 1 NC_012814.1 COG1175 ABC-type sugar transport systems, permease components; MalF-type ABC sugar transport systems permease 580026 8008458 Balac_0486 Bifidobacterium animalis subsp. lactis Bl-04 MalF-type ABC sugar transport systems permease YP_002967927.1 579058 R 580050 CDS YP_002967928.1 241190534 8008459 580313..581311 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 581311 8008459 Balac_0487 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002967928.1 580313 D 580050 CDS YP_002967929.1 241190535 8009579 complement(581933..582958) 1 NC_012814.1 COG0463 Glycosyl transferases involved in cell wall biogenesis; glycosyltransferase 582958 8009579 Balac_0491 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002967929.1 581933 R 580050 CDS YP_002967930.1 241190536 8008461 583089..584678 1 NC_012814.1 COG0628 Predicted permease; hypothetical protein 584678 8008461 Balac_0492 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967930.1 583089 D 580050 CDS YP_002967931.1 241190537 8008462 584678..585964 1 NC_012814.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; hypothetical protein 585964 8008462 Balac_0493 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967931.1 584678 D 580050 CDS YP_002967932.1 241190538 8008463 586187..587047 1 NC_012814.1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 587047 8008463 Balac_0494 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter ATPase YP_002967932.1 586187 D 580050 CDS YP_002967933.1 241190539 8008464 587068..588765 1 NC_012814.1 hypothetical protein 588765 8008464 Balac_0495 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967933.1 587068 D 580050 CDS YP_002967934.1 241190540 8008465 588794..590266 1 NC_012814.1 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase 590266 8008465 Balac_0496 Bifidobacterium animalis subsp. lactis Bl-04 D-alanyl-D-alanine carboxypeptidase YP_002967934.1 588794 D 580050 CDS YP_002967935.1 241190541 8008466 590329..591459 1 NC_012814.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile-lysidine synthetase) 591459 8008466 Balac_0497 Bifidobacterium animalis subsp. lactis Bl-04 tRNA(Ile-lysidine synthetase) YP_002967935.1 590329 D 580050 CDS YP_002967936.1 241190542 8008467 591428..591991 1 NC_012814.1 COG0634 Hypoxanthine-guaninephosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 591991 8008467 Balac_0498 Bifidobacterium animalis subsp. lactis Bl-04 hypoxanthine-guanine phosphoribosyltransferase YP_002967936.1 591428 D 580050 CDS YP_002967937.1 241190543 8008468 591988..594084 1 NC_012814.1 COG0465 ATP-dependent Zn proteases; hypothetical protein 594084 8008468 Balac_0499 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967937.1 591988 D 580050 CDS YP_002967938.1 241190544 8008469 594170..595039 1 NC_012814.1 Dihydroneopterin aldolase 595039 8008469 Balac_0500 Bifidobacterium animalis subsp. lactis Bl-04 Dihydroneopterin aldolase YP_002967938.1 594170 D 580050 CDS YP_002967939.1 241190545 8008470 595036..595653 1 NC_012814.1 hypothetical protein 595653 8008470 Balac_0501 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967939.1 595036 D 580050 CDS YP_002967940.1 241190546 8008471 complement(595720..596625) 1 NC_012814.1 COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase 596625 8008471 Balac_0502 Bifidobacterium animalis subsp. lactis Bl-04 acyl-CoA thioesterase YP_002967940.1 595720 R 580050 CDS YP_002967941.1 241190547 8008472 complement(596863..598539) 1 NC_012814.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 598539 8008472 Balac_0503 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter ATP-binding protein YP_002967941.1 596863 R 580050 CDS YP_002967942.1 241190548 8008473 598707..599135 1 NC_012814.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 599135 8008473 Balac_0504 Bifidobacterium animalis subsp. lactis Bl-04 peptide deformylase YP_002967942.1 598707 D 580050 CDS YP_002967943.1 241190549 8008474 complement(599167..600453) 1 NC_012814.1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine thiol-lyase 600453 8008474 Balac_0505 Bifidobacterium animalis subsp. lactis Bl-04 O-acetylhomoserine thiol-lyase YP_002967943.1 599167 R 580050 CDS YP_002967944.1 241190550 8008475 600741..601373 1 NC_012814.1 COG4721 Predicted membrane protein; hypothetical protein 601373 8008475 Balac_0506 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967944.1 600741 D 580050 CDS YP_002967945.1 241190551 8008476 601655..602563 1 NC_012814.1 hypothetical protein 602563 8008476 Balac_0507 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967945.1 601655 D 580050 CDS YP_002967946.1 241190552 8009580 complement(602801..603649) 1 NC_012814.1 hypothetical protein 603649 8009580 Balac_0509 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967946.1 602801 R 580050 CDS YP_002967947.1 241190553 8008478 604071..604280 1 NC_012814.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 604280 rpmE 8008478 rpmE Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L31 YP_002967947.1 604071 D 580050 CDS YP_002967948.1 241190554 8008479 604574..605926 1 NC_012814.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 605926 8008479 Balac_0511 Bifidobacterium animalis subsp. lactis Bl-04 xylose isomerase YP_002967948.1 604574 D 580050 CDS YP_002967949.1 241190555 8008480 606331..608013 1 NC_012814.1 COG3507 Beta-xylosidase; alpha-L-arabinofuranosidase 608013 8008480 Balac_0512 Bifidobacterium animalis subsp. lactis Bl-04 alpha-L-arabinofuranosidase YP_002967949.1 606331 D 580050 CDS YP_002967950.1 241190556 8008481 complement(608026..609030) 1 NC_012814.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 609030 8008481 Balac_0513 Bifidobacterium animalis subsp. lactis Bl-04 LacI family transcriptional regulator YP_002967950.1 608026 R 580050 CDS YP_002967951.1 241190557 8008482 609361..610638 1 NC_012814.1 COG1653 ABC-type sugar transport system, periplasmic component; putative sugar transporter solute-binding protein 610638 8008482 Balac_0514 Bifidobacterium animalis subsp. lactis Bl-04 putative sugar transporter solute-binding protein YP_002967951.1 609361 D 580050 CDS YP_002967952.1 241190558 8008483 610747..611805 1 NC_012814.1 COG1175 ABC-type sugar transport systems, permease components; putative binding protein-dependent transporter 611805 8008483 Balac_0515 Bifidobacterium animalis subsp. lactis Bl-04 putative binding protein-dependent transporter YP_002967952.1 610747 D 580050 CDS YP_002967953.1 241190559 8008484 611807..612676 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; putative binding protein-dependent transporter 612676 8008484 Balac_0516 Bifidobacterium animalis subsp. lactis Bl-04 putative binding protein-dependent transporter YP_002967953.1 611807 D 580050 CDS YP_002967954.1 241190560 8008485 612754..614379 1 NC_012814.1 COG3507 Beta-xylosidase; Beta-xylosidase 614379 8008485 Balac_0517 Bifidobacterium animalis subsp. lactis Bl-04 Beta-xylosidase YP_002967954.1 612754 D 580050 CDS YP_002967955.1 241190561 8008486 614485..616410 1 NC_012814.1 hypothetical protein 616410 8008486 Balac_0518 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967955.1 614485 D 580050 CDS YP_002967956.1 241190562 8008487 616647..617810 1 NC_012814.1 COG2272 Carboxylesterase type B; esterase 617810 8008487 Balac_0519 Bifidobacterium animalis subsp. lactis Bl-04 esterase YP_002967956.1 616647 D 580050 CDS YP_002967957.1 241190563 8008488 complement(617823..619382) 1 NC_012814.1 COG3507 Beta-xylosidase; pyridine nucleotide-disulfide oxidoreductase 619382 8008488 Balac_0520 Bifidobacterium animalis subsp. lactis Bl-04 pyridine nucleotide-disulfide oxidoreductase YP_002967957.1 617823 R 580050 CDS YP_002967958.1 241190564 8008489 complement(619472..621001) 1 NC_012814.1 COG1070 Sugar (pentulose and hexulose kinases); xylulose kinase 621001 8008489 Balac_0521 Bifidobacterium animalis subsp. lactis Bl-04 xylulose kinase YP_002967958.1 619472 R 580050 CDS YP_002967959.1 241190565 8008490 621188..622423 1 NC_012814.1 COG1940 Transcriptional regulator/sugar kinase; NagC-type transcriptional regulator 622423 8008490 Balac_0522 Bifidobacterium animalis subsp. lactis Bl-04 NagC-type transcriptional regulator YP_002967959.1 621188 D 580050 CDS YP_002967960.1 241190566 8008491 622552..622764 1 NC_012814.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 622764 rpmE 8008491 rpmE Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L31 YP_002967960.1 622552 D 580050 CDS YP_002967961.1 241190567 8008492 622973..624070 1 NC_012814.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 624070 prfA 8008492 prfA Bifidobacterium animalis subsp. lactis Bl-04 peptide chain release factor 1 YP_002967961.1 622973 D 580050 CDS YP_002967962.1 241190568 8008493 624131..625045 1 NC_012814.1 COG2890 Methylase of polypeptide chain release factors; methylase of polypeptide chain release factor 625045 8008493 Balac_0525 Bifidobacterium animalis subsp. lactis Bl-04 methylase of polypeptide chain release factor YP_002967962.1 624131 D 580050 CDS YP_002967963.1 241190569 8008494 625175..625843 1 NC_012814.1 COG0009 Putative translation factor (SUA5); Sua5/YciO/YrdC family protein 625843 8008494 Balac_0526 Bifidobacterium animalis subsp. lactis Bl-04 Sua5/YciO/YrdC family protein YP_002967963.1 625175 D 580050 CDS YP_002967964.1 241190570 8008495 625840..627000 1 NC_012814.1 COG0472 UDP-N-acetylmuramyl pentapeptidephosphotransferase/UDP-N-acetylglucosamine-1- phosphatetransferase; UDP-phosphate-alpha-N- acetylglucosaminyltransferase 627000 8008495 Balac_0527 Bifidobacterium animalis subsp. lactis Bl-04 UDP-phosphate-alpha-N- acetylglucosaminyltransferase YP_002967964.1 625840 D 580050 CDS YP_002967965.1 241190571 8008496 627370..628824 1 NC_012814.1 COG0516 IMP dehydrogenase/GMP reductase; inosine-5'-monophosphate dehydrogenase 628824 8008496 Balac_0528 Bifidobacterium animalis subsp. lactis Bl-04 inosine-5'-monophosphate dehydrogenase YP_002967965.1 627370 D 580050 CDS YP_002967966.1 241190572 8008497 629019..629672 1 NC_012814.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 629672 8008497 Balac_0529 Bifidobacterium animalis subsp. lactis Bl-04 oligoribonuclease YP_002967966.1 629019 D 580050 CDS YP_002967967.1 241190573 8008498 629744..630592 1 NC_012814.1 COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 630592 8008498 Balac_0530 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967967.1 629744 D 580050 CDS YP_002967968.1 241190574 8008499 630633..632102 1 NC_012814.1 COG0507 ATP-dependent exoDNAse (exonuclease V, alpha subunit - helicase superfamily I member); helicase 632102 8008499 Balac_0531 Bifidobacterium animalis subsp. lactis Bl-04 helicase YP_002967968.1 630633 D 580050 CDS YP_002967969.1 241190575 8008500 632203..632634 1 NC_012814.1 hypothetical protein 632634 8008500 Balac_0532 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967969.1 632203 D 580050 CDS YP_002967970.1 241190576 8008501 632739..634556 1 NC_012814.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 634556 8008501 Balac_0533 Bifidobacterium animalis subsp. lactis Bl-04 prolyl-tRNA synthetase YP_002967970.1 632739 D 580050 CDS YP_002967971.1 241190577 8008502 634786..635508 1 NC_012814.1 COG0629 Single-stranded DNA-binding protein; hypothetical protein 635508 8008502 Balac_0534 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967971.1 634786 D 580050 CDS YP_002967972.1 241190578 8008503 complement(635598..637667) 1 NC_012814.1 COG3590 Predicted metalloendopeptidase; M13 family peptidase 637667 8008503 Balac_0535 Bifidobacterium animalis subsp. lactis Bl-04 M13 family peptidase YP_002967972.1 635598 R 580050 CDS YP_002967973.1 241190579 8008504 637928..638548 1 NC_012814.1 COG3247 Uncharacterized conserved protein; hypothetical protein 638548 8008504 Balac_0536 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967973.1 637928 D 580050 CDS YP_002967974.1 241190580 8008505 638699..639502 1 NC_012814.1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 639502 8008505 Balac_0537 Bifidobacterium animalis subsp. lactis Bl-04 methionine aminopeptidase YP_002967974.1 638699 D 580050 CDS YP_002967975.1 241190581 8008506 639727..641019 1 NC_012814.1 COG0372 Citrate synthase; citrate synthase 1 641019 8008506 Balac_0538 Bifidobacterium animalis subsp. lactis Bl-04 citrate synthase 1 YP_002967975.1 639727 D 580050 CDS YP_002967976.1 241190582 8008507 complement(641041..641520) 1 NC_012814.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 641520 8008507 Balac_0539 Bifidobacterium animalis subsp. lactis Bl-04 rRNA large subunit methyltransferase YP_002967976.1 641041 R 580050 CDS YP_002967977.1 241190583 8008508 complement(641629..642612) 1 NC_012814.1 COG2171 TetrahydrodipicolinateN-succinyltransferase; hypothetical protein 642612 8008508 Balac_0540 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967977.1 641629 R 580050 CDS YP_002967978.1 241190584 8008509 642920..643051 1 NC_012814.1 hypothetical protein 643051 8008509 Balac_0541 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967978.1 642920 D 580050 CDS YP_002967979.1 241190585 8008510 643205..644338 1 NC_012814.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 644338 prfB 8008510 prfB Bifidobacterium animalis subsp. lactis Bl-04 peptide chain release factor 2 YP_002967979.1 643205 D 580050 CDS YP_002967980.1 241190586 8008511 644384..645712 1 NC_012814.1 COG2884 Predicted ATPase involved in cell division; FtsE-like ATP binding protein in cell division 645712 8008511 Balac_0543 Bifidobacterium animalis subsp. lactis Bl-04 FtsE-like ATP binding protein in cell division YP_002967980.1 644384 D 580050 CDS YP_002967981.1 241190587 8008512 645716..646639 1 NC_012814.1 COG2177 Cell division protein; FtsX-like protein 646639 8008512 Balac_0544 Bifidobacterium animalis subsp. lactis Bl-04 FtsX-like protein YP_002967981.1 645716 D 580050 CDS YP_002967982.1 241190588 8008513 646865..648208 1 NC_012814.1 COG3942 Surface antigen; Surface antigen 648208 8008513 Balac_0545 Bifidobacterium animalis subsp. lactis Bl-04 Surface antigen YP_002967982.1 646865 D 580050 CDS YP_002967983.1 241190589 8008514 648607..649098 1 NC_012814.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 649098 smpB 8008514 smpB Bifidobacterium animalis subsp. lactis Bl-04 SsrA-binding protein YP_002967983.1 648607 D 580050 CDS YP_002967984.1 241190590 8008515 649177..649416 1 NC_012814.1 hypothetical protein 649416 8008515 Balac_0547 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967984.1 649177 D 580050 CDS YP_002967985.1 241190591 8008516 649463..650392 1 NC_012814.1 COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; ABC transporter substrate-binding protein 650392 8008516 Balac_0548 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002967985.1 649463 D 580050 CDS YP_002967986.1 241190592 8008517 650607..651542 1 NC_012814.1 COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; ABC transporter substrate-binding protein 651542 8008517 Balac_0549 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002967986.1 650607 D 580050 CDS YP_002967987.1 241190593 8008518 651739..652725 1 NC_012814.1 COG0765 ABC-type amino acid transport system, permease component; ABC transporter permease 652725 8008518 Balac_0550 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002967987.1 651739 D 580050 CDS YP_002967988.1 241190594 8008519 652753..653607 1 NC_012814.1 COG1126 ABC-type polar amino acid transport system, ATPase component; ABC transporter ATP-binding protein 653607 8008519 Balac_0551 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002967988.1 652753 D 580050 CDS YP_002967989.1 241190595 8008520 complement(654082..655017) 1 NC_012814.1 hypothetical protein 655017 8008520 Balac_0552 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967989.1 654082 R 580050 CDS YP_002967990.1 241190596 8008521 complement(656514..657200) 1 NC_012814.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 657200 8008521 Balac_0553 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002967990.1 656514 R 580050 CDS YP_002967991.1 241190597 8008522 657536..659362 1 NC_012814.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 659362 8008522 Balac_0554 Bifidobacterium animalis subsp. lactis Bl-04 glucosamine--fructose-6-phosphate aminotransferase YP_002967991.1 657536 D 580050 CDS YP_002967992.1 241190598 8008523 659380..660108 1 NC_012814.1 COG0564 Pseudouridylate synthases, 23SRNA-specific; 23S RNA-specific pseudouridylate synthase 660108 8008523 Balac_0555 Bifidobacterium animalis subsp. lactis Bl-04 23S RNA-specific pseudouridylate synthase YP_002967992.1 659380 D 580050 CDS YP_002967993.1 241190599 8008524 660146..660547 1 NC_012814.1 hypothetical protein 660547 8008524 Balac_0556 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002967993.1 660146 D 580050 CDS YP_002967994.1 241190600 8008525 complement(660554..661312) 1 NC_012814.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 661312 8008525 Balac_0557 Bifidobacterium animalis subsp. lactis Bl-04 pantothenate kinase YP_002967994.1 660554 R 580050 CDS YP_002967995.1 241190601 8008526 661482..663233 1 NC_012814.1 COG0747 ABC-type dipeptide transport system, periplasmic component; dipeptide ABC transporter periplasmic component 663233 8008526 Balac_0558 Bifidobacterium animalis subsp. lactis Bl-04 dipeptide ABC transporter periplasmic component YP_002967995.1 661482 D 580050 CDS YP_002967996.1 241190602 8008527 663273..664235 1 NC_012814.1 COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 664235 8008527 Balac_0559 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter permease YP_002967996.1 663273 D 580050 CDS YP_002967997.1 241190603 8008528 664228..665112 1 NC_012814.1 COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 665112 8008528 Balac_0560 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter permease YP_002967997.1 664228 D 580050 CDS YP_002967998.1 241190604 8008529 665109..665906 1 NC_012814.1 COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; peptide ABC transporter ATP-binding protein 665906 8008529 Balac_0561 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter ATP-binding protein YP_002967998.1 665109 D 580050 CDS YP_002967999.1 241190605 8008530 665899..666687 1 NC_012814.1 COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; oligopeptide ABC transporter ATPase 666687 8008530 Balac_0562 Bifidobacterium animalis subsp. lactis Bl-04 oligopeptide ABC transporter ATPase YP_002967999.1 665899 D 580050 CDS YP_002968000.1 241190606 8008531 complement(666777..667952) 1 NC_012814.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 667952 8008531 Balac_0563 Bifidobacterium animalis subsp. lactis Bl-04 cystathionine gamma-synthase YP_002968000.1 666777 R 580050 CDS YP_002968001.1 241190607 8008532 complement(668029..669048) 1 NC_012814.1 COG0031 Cysteine synthase; cystathionine beta-synthase 669048 8008532 Balac_0564 Bifidobacterium animalis subsp. lactis Bl-04 cystathionine beta-synthase YP_002968001.1 668029 R 580050 CDS YP_002968002.1 241190608 8008533 complement(669434..671392) 1 NC_012814.1 COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ 671392 8008533 Balac_0565 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent DNA helicase RecQ YP_002968002.1 669434 R 580050 CDS YP_002968003.1 241190609 8008534 671694..672614 1 NC_012814.1 COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 672614 8008534 Balac_0566 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968003.1 671694 D 580050 CDS YP_002968004.1 241190610 8008535 complement(672787..673344) 1 NC_012814.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 673344 8008535 Balac_0567 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968004.1 672787 R 580050 CDS YP_002968005.1 241190611 8008536 673625..673753 1 NC_012814.1 hypothetical protein 673753 8008536 Balac_0568 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968005.1 673625 D 580050 CDS YP_002968006.1 241190612 8008537 complement(673885..674088) 1 NC_012814.1 hypothetical protein 674088 8008537 Balac_0569 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968006.1 673885 R 580050 CDS YP_002968007.1 241190613 8008538 674623..674943 1 NC_012814.1 hypothetical protein 674943 8008538 Balac_0570 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968007.1 674623 D 580050 CDS YP_002968008.1 241190614 8008539 675085..675426 1 NC_012814.1 hypothetical protein 675426 8008539 Balac_0571 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968008.1 675085 D 580050 CDS YP_002968009.1 241190615 8008540 complement(675450..675833) 1 NC_012814.1 hypothetical protein 675833 8008540 Balac_0572 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968009.1 675450 R 580050 CDS YP_002968010.1 241190616 8008541 676003..676404 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases includingoxidative damage repair enzymes; putative pyrophosphohydrolase 676404 8008541 Balac_0573 Bifidobacterium animalis subsp. lactis Bl-04 putative pyrophosphohydrolase YP_002968010.1 676003 D 580050 CDS YP_002968011.1 241190617 8008542 676457..679582 1 NC_012814.1 COG3886 Predicted HKD family nuclease; superfamily II DNA/RNA helicase 679582 8008542 Balac_0574 Bifidobacterium animalis subsp. lactis Bl-04 superfamily II DNA/RNA helicase YP_002968011.1 676457 D 580050 CDS YP_002968012.1 241190618 8008543 680207..680563 1 NC_012814.1 COG3177 Uncharacterized conserved protein; hypothetical protein 680563 8008543 Balac_0575 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968012.1 680207 D 580050 CDS YP_002968013.1 241190619 8008544 680996..682963 1 NC_012814.1 COG1479 Uncharacterized conserved protein; type I restriction-modification system protein 682963 8008544 Balac_0576 Bifidobacterium animalis subsp. lactis Bl-04 type I restriction-modification system protein YP_002968013.1 680996 D 580050 CDS YP_002968014.1 241190620 8008545 683202..683714 1 NC_012814.1 COG3600 Uncharacterized phage-associated protein; putative prophage protein 683714 8008545 Balac_0577 Bifidobacterium animalis subsp. lactis Bl-04 putative prophage protein YP_002968014.1 683202 D 580050 CDS YP_002968015.1 241190621 8008546 683732..684226 1 NC_012814.1 COG3654 Prophage maintenance system killer protein; hypothetical protein 684226 8008546 Balac_0578 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968015.1 683732 D 580050 CDS YP_002968016.1 241190622 8008547 complement(684223..684702) 1 NC_012814.1 COG1247 Sortase and related acyltransferases; hypothetical protein 684702 8008547 Balac_0579 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968016.1 684223 R 580050 CDS YP_002968017.1 241190623 8008548 complement(684769..685566) 1 NC_012814.1 COG3752 Predicted membrane protein; hypothetical protein 685566 8008548 Balac_0580 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968017.1 684769 R 580050 CDS YP_002968018.1 241190624 8008549 complement(685674..686687) 1 NC_012814.1 COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 686687 8008549 Balac_0581 Bifidobacterium animalis subsp. lactis Bl-04 glycerol dehydrogenase YP_002968018.1 685674 R 580050 CDS YP_002968019.1 241190625 8008550 687068..687568 1 NC_012814.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 687568 8008550 Balac_0582 Bifidobacterium animalis subsp. lactis Bl-04 S-ribosylhomocysteinase YP_002968019.1 687068 D 580050 CDS YP_002968020.1 241190626 8008551 687681..688205 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Histone acetyltransferase 688205 8008551 Balac_0583 Bifidobacterium animalis subsp. lactis Bl-04 Histone acetyltransferase YP_002968020.1 687681 D 580050 CDS YP_002968021.1 241190627 8008552 688281..689648 1 NC_012814.1 COG0787 Alanine racemase; alanine racemase 689648 8008552 Balac_0584 Bifidobacterium animalis subsp. lactis Bl-04 alanine racemase YP_002968021.1 688281 D 580050 CDS YP_002968022.1 241190628 8008553 689758..691839 1 NC_012814.1 synthesizes RNA primers at the replication forks; DNA primase 691839 dnaG 8008553 dnaG Bifidobacterium animalis subsp. lactis Bl-04 DNA primase YP_002968022.1 689758 D 580050 CDS YP_002968023.1 241190629 8008554 692054..693247 1 NC_012814.1 COG0471 Di- and tricarboxylate transporters; transport protein 693247 8008554 Balac_0586 Bifidobacterium animalis subsp. lactis Bl-04 transport protein YP_002968023.1 692054 D 580050 CDS YP_002968024.1 241190630 8009581 complement(693549..695396) 1 NC_012814.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 695396 8009581 Balac_0588 Bifidobacterium animalis subsp. lactis Bl-04 1-deoxy-D-xylulose-5-phosphate synthase YP_002968024.1 693549 R 580050 CDS YP_002968025.1 241190631 8008556 695656..696153 1 NC_012814.1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR mutase); phosphoribosylaminoimidazole carboxylasecatalytic subunit 696153 8008556 Balac_0589 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylaminoimidazole carboxylasecatalytic subunit YP_002968025.1 695656 D 580050 CDS YP_002968026.1 241190632 8008557 696137..697288 1 NC_012814.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 697288 8008557 Balac_0590 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002968026.1 696137 D 580050 CDS YP_002968027.1 241190633 8008558 697329..697730 1 NC_012814.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; metal uptake regulator ferric uptake regulator protein 697730 8008558 Balac_0591 Bifidobacterium animalis subsp. lactis Bl-04 metal uptake regulator ferric uptake regulator protein YP_002968027.1 697329 D 580050 CDS YP_002968028.1 241190634 8008559 complement(697831..700599) 1 NC_012814.1 COG2898 Uncharacterized conserved protein; hypothetical protein 700599 8008559 Balac_0592 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968028.1 697831 R 580050 CDS YP_002968029.1 241190635 8008560 complement(700596..701969) 1 NC_012814.1 COG0627 Predicted esterase; putative esterase 701969 8008560 Balac_0593 Bifidobacterium animalis subsp. lactis Bl-04 putative esterase YP_002968029.1 700596 R 580050 CDS YP_002968030.1 241190636 8008561 complement(702162..703424) 1 NC_012814.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 703424 8008561 Balac_0594 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylamine--glycine ligase YP_002968030.1 702162 R 580050 CDS YP_002968031.1 241190637 8008562 complement(703472..704506) 1 NC_012814.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 704506 8008562 Balac_0595 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylaminoimidazole synthetase YP_002968031.1 703472 R 580050 CDS YP_002968032.1 241190638 8008563 complement(704583..706139) 1 NC_012814.1 COG0034 Glutamine phosphoribosylpyrophosphateamidotransferase; amidophosphoribosyltransferase 706139 8008563 Balac_0596 Bifidobacterium animalis subsp. lactis Bl-04 amidophosphoribosyltransferase YP_002968032.1 704583 R 580050 CDS YP_002968033.1 241190639 8008564 706392..707870 1 NC_012814.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA-repair protein 707870 8008564 Balac_0597 Bifidobacterium animalis subsp. lactis Bl-04 DNA-repair protein YP_002968033.1 706392 D 580050 CDS YP_002968034.1 241190640 8008565 707867..708280 1 NC_012814.1 hypothetical protein 708280 8008565 Balac_0598 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968034.1 707867 D 580050 CDS YP_002968035.1 241190641 8008566 708287..709570 1 NC_012814.1 COG3597 Uncharacterized protein/domain associated with GTPases; GTPase protein 709570 8008566 Balac_0599 Bifidobacterium animalis subsp. lactis Bl-04 GTPase protein YP_002968035.1 708287 D 580050 CDS YP_002968036.1 241190642 8008567 709733..710404 1 NC_012814.1 hypothetical protein 710404 8008567 Balac_0600 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968036.1 709733 D 580050 CDS YP_002968037.1 241190643 8008568 complement(710572..711081) 1 NC_012814.1 COG3467 Predicted flavin-nucleotide-binding protein; hypothetical protein 711081 8008568 Balac_0601 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968037.1 710572 R 580050 CDS YP_002968038.1 241190644 8008569 complement(711266..711862) 1 NC_012814.1 COG1396 Predicted transcriptional regulators; hypothetical protein 711862 8008569 Balac_0602 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968038.1 711266 R 580050 CDS YP_002968039.1 241190645 8008570 complement(711991..712167) 1 NC_012814.1 hypothetical protein 712167 8008570 Balac_0603 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968039.1 711991 R 580050 CDS YP_002968040.1 241190646 8008571 712166..712309 1 NC_012814.1 hypothetical protein 712309 8008571 Balac_0604 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968040.1 712166 D 580050 CDS YP_002968041.1 241190647 8008572 712413..713951 1 NC_012814.1 hypothetical protein 713951 8008572 Balac_0605 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968041.1 712413 D 580050 CDS YP_002968042.1 241190648 8008573 713977..714705 1 NC_012814.1 hypothetical protein 714705 8008573 Balac_0606 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968042.1 713977 D 580050 CDS YP_002968043.1 241190649 8008574 714746..715195 1 NC_012814.1 hypothetical protein 715195 8008574 Balac_0607 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968043.1 714746 D 580050 CDS YP_002968044.1 241190650 8008575 715269..715853 1 NC_012814.1 hypothetical protein 715853 8008575 Balac_0608 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968044.1 715269 D 580050 CDS YP_002968045.1 241190651 8008576 715885..717117 1 NC_012814.1 COG4260 Putative virion core protein (lumpy skin disease virus); putative virion core protein 717117 8008576 Balac_0609 Bifidobacterium animalis subsp. lactis Bl-04 putative virion core protein YP_002968045.1 715885 D 580050 CDS YP_002968046.1 241190652 8008577 complement(717419..721153) 1 NC_012814.1 COG0046 Phosphoribosylformylglycinamidine (FGAM synthase, synthetase domain); hypothetical protein 721153 8008577 Balac_0610 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968046.1 717419 R 580050 CDS YP_002968047.1 241190653 8008578 complement(721263..722015) 1 NC_012814.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 722015 8008578 Balac_0611 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002968047.1 721263 R 580050 CDS YP_002968048.1 241190654 8008579 complement(722152..723393) 1 NC_012814.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 723393 purT 8008579 purT Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosylglycinamide formyltransferase 2 YP_002968048.1 722152 R 580050 CDS YP_002968049.1 241190655 8008580 723519..724721 1 NC_012814.1 COG0438 Glycosyltransferase; glycosyltransferase 724721 8008580 Balac_0613 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968049.1 723519 D 580050 CDS YP_002968050.1 241190656 8008581 complement(724790..725815) 1 NC_012814.1 COG2008 Threonine aldolase; low specificity-threonine aldolase 725815 8008581 Balac_0614 Bifidobacterium animalis subsp. lactis Bl-04 low specificity-threonine aldolase YP_002968050.1 724790 R 580050 CDS YP_002968051.1 241190657 8009582 726586..726720 1 NC_012814.1 hypothetical protein 726720 8009582 Balac_0616 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968051.1 726586 D 580050 CDS YP_002968052.2 394895232 8008583 726996..727367 1 NC_012814.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 727367 rpsL 8008583 rpsL Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S12 YP_002968052.2 726996 D 580050 CDS YP_002968053.1 241190659 8008584 727373..727843 1 NC_012814.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 727843 8008584 Balac_0618 Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S7 YP_002968053.1 727373 D 580050 CDS YP_002968054.1 241190660 8008585 727877..730006 1 NC_012814.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 730006 8008585 Balac_0619 Bifidobacterium animalis subsp. lactis Bl-04 elongation factor G YP_002968054.1 727877 D 580050 CDS YP_002968055.1 241190661 8008586 730184..731383 1 NC_012814.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 731383 8008586 Balac_0620 Bifidobacterium animalis subsp. lactis Bl-04 elongation factor Tu YP_002968055.1 730184 D 580050 CDS YP_002968056.1 241190662 8008587 complement(731665..732339) 1 NC_012814.1 hypothetical protein 732339 8008587 Balac_0621 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968056.1 731665 R 580050 CDS YP_002968057.1 241190663 8008588 complement(732480..733049) 1 NC_012814.1 COG0492 Thioredoxin reductase; hypothetical protein 733049 8008588 Balac_0622 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968057.1 732480 R 580050 CDS YP_002968058.1 241190664 8008589 733324..733887 1 NC_012814.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 733887 8008589 Balac_0623 Bifidobacterium animalis subsp. lactis Bl-04 elongation factor P YP_002968058.1 733324 D 580050 CDS YP_002968059.1 241190665 8008590 733984..734448 1 NC_012814.1 COG0781 Transcription termination factor; transcription termination factor 734448 8008590 Balac_0624 Bifidobacterium animalis subsp. lactis Bl-04 transcription termination factor YP_002968059.1 733984 D 580050 CDS YP_002968060.1 241190666 8008591 734522..735757 1 NC_012814.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 735757 8008591 Balac_0625 Bifidobacterium animalis subsp. lactis Bl-04 carbamoyl phosphate synthase small subunit YP_002968060.1 734522 D 580050 CDS YP_002968061.1 241190667 8008592 735750..739160 1 NC_012814.1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoylphosphate synthase large subunit 739160 8008592 Balac_0626 Bifidobacterium animalis subsp. lactis Bl-04 carbamoylphosphate synthase large subunit YP_002968061.1 735750 D 580050 CDS YP_002968062.1 241190668 8008593 739157..740128 1 NC_012814.1 COG0284 Orotidine-5-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 740128 8008593 Balac_0627 Bifidobacterium animalis subsp. lactis Bl-04 orotidine 5'-phosphate decarboxylase YP_002968062.1 739157 D 580050 CDS YP_002968063.1 241190669 8008594 740125..740754 1 NC_012814.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 740754 gmk 8008594 gmk Bifidobacterium animalis subsp. lactis Bl-04 guanylate kinase YP_002968063.1 740125 D 580050 CDS YP_002968064.1 241190670 8008595 complement(740851..742686) 1 NC_012814.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 742686 8008595 Balac_0629 Bifidobacterium animalis subsp. lactis Bl-04 dihydroxy-acid dehydratase YP_002968064.1 740851 R 580050 CDS YP_002968065.1 241190671 8008596 742883..743167 1 NC_012814.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 743167 8008596 Balac_0630 Bifidobacterium animalis subsp. lactis Bl-04 DNA-directed RNA polymerase subunit omega YP_002968065.1 742883 D 580050 CDS YP_002968066.1 241190672 8008597 743348..744574 1 NC_012814.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 744574 8008597 Balac_0631 Bifidobacterium animalis subsp. lactis Bl-04 S-adenosylmethionine synthetase YP_002968066.1 743348 D 580050 CDS YP_002968067.1 241190673 8008598 744694..745977 1 NC_012814.1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane-fatty-acyl-phospholipid synthase 745977 8008598 Balac_0632 Bifidobacterium animalis subsp. lactis Bl-04 cyclopropane-fatty-acyl-phospholipid synthase YP_002968067.1 744694 D 580050 CDS YP_002968068.1 241190674 8008599 746131..748374 1 NC_012814.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 748374 8008599 Balac_0633 Bifidobacterium animalis subsp. lactis Bl-04 primosome assembly protein PriA YP_002968068.1 746131 D 580050 CDS YP_002968069.1 241190675 8008600 748546..749457 1 NC_012814.1 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 749457 8008600 Balac_0634 Bifidobacterium animalis subsp. lactis Bl-04 methionyl-tRNA formyltransferase YP_002968069.1 748546 D 580050 CDS YP_002968070.1 241190676 8008601 complement(749557..750258) 1 NC_012814.1 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase 750258 8008601 Balac_0635 Bifidobacterium animalis subsp. lactis Bl-04 phosphoserine phosphatase YP_002968070.1 749557 R 580050 CDS YP_002968071.1 241190677 8008602 750368..750991 1 NC_012814.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 750991 8008602 Balac_0636 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968071.1 750368 D 580050 CDS YP_002968072.1 241190678 8008603 751117..752685 1 NC_012814.1 COG0464 ATPases of the AAA+ class; ATPase AAA 752685 8008603 Balac_0637 Bifidobacterium animalis subsp. lactis Bl-04 ATPase AAA YP_002968072.1 751117 D 580050 CDS YP_002968073.1 241190679 8008604 752768..754372 1 NC_012814.1 proteasome-associated protein 754372 8008604 Balac_0638 Bifidobacterium animalis subsp. lactis Bl-04 proteasome-associated protein YP_002968073.1 752768 D 580050 CDS YP_002968074.1 241190680 8008605 754492..755385 1 NC_012814.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol monophosphatase 755385 8008605 Balac_0639 Bifidobacterium animalis subsp. lactis Bl-04 inositol monophosphatase YP_002968074.1 754492 D 580050 CDS YP_002968075.1 241190681 8008606 755474..755689 1 NC_012814.1 hypothetical protein 755689 8008606 Balac_0640 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968075.1 755474 D 580050 CDS YP_002968076.1 241190682 8008607 755689..757179 1 NC_012814.1 proteasome-associated protein 757179 8008607 Balac_0641 Bifidobacterium animalis subsp. lactis Bl-04 proteasome-associated protein YP_002968076.1 755689 D 580050 CDS YP_002968077.1 241190683 8008608 complement(757257..757538) 1 NC_012814.1 COG0776 Bacterial nucleoid DNA-binding protein; DNA-binding protein HB1 757538 8008608 Balac_0642 Bifidobacterium animalis subsp. lactis Bl-04 DNA-binding protein HB1 YP_002968077.1 757257 R 580050 CDS YP_002968078.1 241190684 8008609 complement(757705..760209) 1 NC_012814.1 COG0392 Predicted integral membrane protein; hypothetical protein 760209 8008609 Balac_0643 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968078.1 757705 R 580050 CDS YP_002968079.1 241190685 8008610 complement(760308..761753) 1 NC_012814.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 761753 8008610 Balac_0644 Bifidobacterium animalis subsp. lactis Bl-04 adenylosuccinate lyase YP_002968079.1 760308 R 580050 CDS YP_002968080.1 241190686 8008611 complement(761804..763354) 1 NC_012814.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 763354 8008611 Balac_0645 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968080.1 761804 R 580050 CDS YP_002968081.1 241190687 8008612 complement(763363..763641) 1 NC_012814.1 hypothetical protein 763641 8008612 Balac_0646 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968081.1 763363 R 580050 CDS YP_002968082.1 241190688 8008613 complement(763772..764371) 1 NC_012814.1 cell surface elastin binding protein EbpS 764371 8008613 Balac_0647 Bifidobacterium animalis subsp. lactis Bl-04 cell surface elastin binding protein EbpS YP_002968082.1 763772 R 580050 CDS YP_002968083.1 241190689 8008614 complement(764368..765372) 1 NC_012814.1 hypothetical protein 765372 8008614 Balac_0648 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968083.1 764368 R 580050 CDS YP_002968084.1 241190690 8008615 complement(765369..766430) 1 NC_012814.1 COG2304 Uncharacterized protein containing a vonWillebrand factor type A (vWA domain); von Willebrand factor A 766430 8008615 Balac_0649 Bifidobacterium animalis subsp. lactis Bl-04 von Willebrand factor A YP_002968084.1 765369 R 580050 CDS YP_002968085.1 241190691 8008616 complement(766427..766939) 1 NC_012814.1 hypothetical protein 766939 8008616 Balac_0650 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968085.1 766427 R 580050 CDS YP_002968086.1 241190692 8008617 complement(766940..767905) 1 NC_012814.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWAdomain)); hypothetical protein 767905 8008617 Balac_0651 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968086.1 766940 R 580050 CDS YP_002968087.1 241190693 8008618 complement(767902..768858) 1 NC_012814.1 COG0714 MoxR-like ATPases; magnesium chelatase family protein 768858 8008618 Balac_0652 Bifidobacterium animalis subsp. lactis Bl-04 magnesium chelatase family protein YP_002968087.1 767902 R 580050 CDS YP_002968088.1 241190694 8008619 complement(769093..769812) 1 NC_012814.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 769812 8008619 Balac_0653 Bifidobacterium animalis subsp. lactis Bl-04 uracil-DNA glycosylase YP_002968088.1 769093 R 580050 CDS YP_002968089.1 241190695 8008620 769989..770672 1 NC_012814.1 hypothetical protein 770672 8008620 Balac_0654 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968089.1 769989 D 580050 CDS YP_002968090.1 241190696 8008621 770979..771191 1 NC_012814.1 COG1278 Cold shock proteins; cold-shock DNA-binding domain-containing protein 771191 cspA 8008621 cspA Bifidobacterium animalis subsp. lactis Bl-04 cold-shock DNA-binding domain-containing protein YP_002968090.1 770979 D 580050 CDS YP_002968091.1 241190697 8008622 771407..773020 1 NC_012814.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 773020 groEL 8008622 groEL Bifidobacterium animalis subsp. lactis Bl-04 molecular chaperone GroEL YP_002968091.1 771407 D 580050 CDS YP_002968092.1 241190698 8008623 complement(773160..773453) 1 NC_012814.1 hypothetical protein 773453 8008623 Balac_0657 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968092.1 773160 R 580050 CDS YP_002968093.1 241190699 8008624 773531..774538 1 NC_012814.1 hypothetical protein 774538 8008624 Balac_0658 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968093.1 773531 D 580050 CDS YP_002968094.1 241190700 8008625 774619..775329 1 NC_012814.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 775329 8008625 Balac_0659 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002968094.1 774619 D 580050 CDS YP_002968095.1 241190701 8008626 775403..777148 1 NC_012814.1 COG0642 Signal transduction histidine kinase; sensor protein 777148 8008626 Balac_0660 Bifidobacterium animalis subsp. lactis Bl-04 sensor protein YP_002968095.1 775403 D 580050 CDS YP_002968096.1 241190702 8008627 777275..777718 1 NC_012814.1 COG1278 Cold shock proteins; cold shock protein 777718 cspB 8008627 cspB Bifidobacterium animalis subsp. lactis Bl-04 cold shock protein YP_002968096.1 777275 D 580050 CDS YP_002968097.1 241190703 8008628 777720..778850 1 NC_012814.1 hypothetical protein 778850 8008628 Balac_0662 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968097.1 777720 D 580050 CDS YP_002968098.1 241190704 8008629 complement(778933..779955) 1 NC_012814.1 hypothetical protein 779955 8008629 Balac_0663 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968098.1 778933 R 580050 CDS YP_002968099.1 241190705 8008630 complement(780120..781097) 1 NC_012814.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein 781097 8008630 Balac_0664 Bifidobacterium animalis subsp. lactis Bl-04 Universal stress protein YP_002968099.1 780120 R 580050 CDS YP_002968100.1 241190706 8008631 781404..783956 1 NC_012814.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 783956 clpC 8008631 clpC Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent Clp protease ATP-binding subunit YP_002968100.1 781404 D 580050 CDS YP_002968101.1 241190707 8008632 complement(784358..786160) 1 NC_012814.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 786160 aspS 8008632 aspS Bifidobacterium animalis subsp. lactis Bl-04 aspartyl-tRNA synthetase YP_002968101.1 784358 R 580050 CDS YP_002968102.1 241190708 8008633 complement(786219..787565) 1 NC_012814.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 787565 hisS 8008633 hisS Bifidobacterium animalis subsp. lactis Bl-04 histidyl-tRNA synthetase YP_002968102.1 786219 R 580050 CDS YP_002968103.1 241190709 8008634 787753..789171 1 NC_012814.1 hypothetical protein 789171 8008634 Balac_0668 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968103.1 787753 D 580050 CDS YP_002968104.1 241190710 8008635 789350..790138 1 NC_012814.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 790138 8008635 Balac_0669 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968104.1 789350 D 580050 CDS YP_002968105.1 241190711 8008636 790307..791092 1 NC_012814.1 COG1126 ABC-type polar amino acid transport system, ATPase component; ATP-binding protein of ABC transporter for glutamate 791092 8008636 Balac_0670 Bifidobacterium animalis subsp. lactis Bl-04 ATP-binding protein of ABC transporter for glutamate YP_002968105.1 790307 D 580050 CDS YP_002968106.1 241190712 8008637 791178..792017 1 NC_012814.1 COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein 792017 8008637 Balac_0671 Bifidobacterium animalis subsp. lactis Bl-04 amino acid ABC transporter substrate-binding protein YP_002968106.1 791178 D 580050 CDS YP_002968107.1 241190713 8008638 792023..792700 1 NC_012814.1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 792700 8008638 Balac_0672 Bifidobacterium animalis subsp. lactis Bl-04 amino acid ABC transporter permease YP_002968107.1 792023 D 580050 CDS YP_002968108.1 241190714 8008639 792704..793795 1 NC_012814.1 COG0765 ABC-type amino acid transport system, permease component; glutamate ABC transporter permease 793795 8008639 Balac_0673 Bifidobacterium animalis subsp. lactis Bl-04 glutamate ABC transporter permease YP_002968108.1 792704 D 580050 CDS YP_002968109.1 241190715 8008640 793908..794876 1 NC_012814.1 COG2326 Uncharacterized conserved protein; hypothetical protein 794876 8008640 Balac_0674 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968109.1 793908 D 580050 CDS YP_002968110.1 241190716 8008641 complement(794891..797479) 1 NC_012814.1 COG4581 Superfamily II RNA helicase; DEAD box-like helicase 797479 8008641 Balac_0675 Bifidobacterium animalis subsp. lactis Bl-04 DEAD box-like helicase YP_002968110.1 794891 R 580050 CDS YP_002968111.1 241190717 8008642 797610..799124 1 NC_012814.1 COG2256 ATPase related to the helicase subunit ofthe Holliday junction resolvase; recombination factor protein RarA 799124 8008642 Balac_0676 Bifidobacterium animalis subsp. lactis Bl-04 recombination factor protein RarA YP_002968111.1 797610 D 580050 CDS YP_002968112.1 241190718 8008643 799066..800568 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; efflux-type transporter 800568 8008643 Balac_0677 Bifidobacterium animalis subsp. lactis Bl-04 efflux-type transporter YP_002968112.1 799066 D 580050 CDS YP_002968113.1 241190719 8008644 complement(800646..802481) 1 NC_012814.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty-acid--CoA ligase 802481 8008644 Balac_0678 Bifidobacterium animalis subsp. lactis Bl-04 long-chain-fatty-acid--CoA ligase YP_002968113.1 800646 R 580050 CDS YP_002968114.1 241190720 8008645 802762..803841 1 NC_012814.1 COG3328 Transposase and inactivated derivatives; transposase 803841 8008645 Balac_0679 Bifidobacterium animalis subsp. lactis Bl-04 transposase YP_002968114.1 802762 D 580050 CDS YP_002968115.1 241190721 8008646 803901..804023 1 NC_012814.1 hypothetical protein 804023 8008646 Balac_0680 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968115.1 803901 D 580050 CDS YP_002968116.1 241190722 8008647 804308..805873 1 NC_012814.1 COG4715 Uncharacterized conserved protein; hypothetical protein 805873 8008647 Balac_0681 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968116.1 804308 D 580050 CDS YP_002968117.1 241190723 8008648 805979..806635 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 806635 8008648 Balac_0682 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968117.1 805979 D 580050 CDS YP_002968118.1 241190724 8008649 806652..807020 1 NC_012814.1 COG3824 Uncharacterized protein conserved in bacteria; putative Zn-dependent protease 807020 8008649 Balac_0683 Bifidobacterium animalis subsp. lactis Bl-04 putative Zn-dependent protease YP_002968118.1 806652 D 580050 CDS YP_002968119.1 241190725 8008650 complement(807099..807509) 1 NC_012814.1 COG3304 Predicted membrane protein; hypothetical protein 807509 8008650 Balac_0684 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968119.1 807099 R 580050 CDS YP_002968120.1 241190726 8008651 807664..808404 1 NC_012814.1 COG0819 Putative transcription activator; transcriptional activator TenA 808404 8008651 Balac_0685 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional activator TenA YP_002968120.1 807664 D 580050 CDS YP_002968121.1 241190727 8008652 complement(808527..808832) 1 NC_012814.1 COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; hypothetical protein 808832 8008652 Balac_0686 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968121.1 808527 R 580050 CDS YP_002968122.1 241190728 8008653 complement(809103..809939) 1 NC_012814.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; morphine 6-dehydrogenase 809939 8008653 Balac_0687 Bifidobacterium animalis subsp. lactis Bl-04 morphine 6-dehydrogenase YP_002968122.1 809103 R 580050 CDS YP_002968123.1 241190729 8008654 complement(810300..812597) 1 NC_012814.1 COG1122 ABC-type cobalt transport system, ATPase component; cobalt import ATP-binding/permease cbiO 812597 8008654 Balac_0688 Bifidobacterium animalis subsp. lactis Bl-04 cobalt import ATP-binding/permease cbiO YP_002968123.1 810300 R 580050 CDS YP_002968124.1 241190730 8008655 complement(812594..813085) 1 NC_012814.1 COG3601 Predicted membrane protein; hypothetical protein 813085 8008655 Balac_0689 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968124.1 812594 R 580050 CDS YP_002968125.1 241190731 8008656 813631..814401 1 NC_012814.1 COG1940 Transcriptional regulator/sugar kinase; polyphosphate glucokinase 814401 8008656 Balac_0690 Bifidobacterium animalis subsp. lactis Bl-04 polyphosphate glucokinase YP_002968125.1 813631 D 580050 CDS YP_002968126.1 241190732 8008657 814581..815666 1 NC_012814.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 815666 8008657 Balac_0691 Bifidobacterium animalis subsp. lactis Bl-04 aminotransferase YP_002968126.1 814581 D 580050 CDS YP_002968127.1 241190733 8008658 complement(815645..816460) 1 NC_012814.1 COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 816460 8008658 Balac_0692 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968127.1 815645 R 580050 CDS YP_002968128.1 241190734 8008659 complement(816530..818743) 1 NC_012814.1 hypothetical protein 818743 8008659 Balac_0693 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968128.1 816530 R 580050 CDS YP_002968129.1 241190735 8008660 818826..822155 1 NC_012814.1 hypothetical protein 822155 8008660 Balac_0694 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968129.1 818826 D 580050 CDS YP_002968130.1 241190736 8008661 822269..824860 1 NC_012814.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); LigA 824860 8008661 Balac_0695 Bifidobacterium animalis subsp. lactis Bl-04 LigA YP_002968130.1 822269 D 580050 CDS YP_002968131.1 241190737 8008662 complement(824930..826042) 1 NC_012814.1 COG0489 ATPases involved in chromosome partitioning; hypothetical protein 826042 8008662 Balac_0696 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968131.1 824930 R 580050 CDS YP_002968132.1 241190738 8008663 complement(826173..826781) 1 NC_012814.1 COG4721 Predicted membrane protein; hypothetical protein 826781 8008663 Balac_0697 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968132.1 826173 R 580050 CDS YP_002968133.1 241190739 8008664 complement(827019..828455) 1 NC_012814.1 COG0174 Glutamine synthetase; glutamine synthetase 1 828455 8008664 Balac_0698 Bifidobacterium animalis subsp. lactis Bl-04 glutamine synthetase 1 YP_002968133.1 827019 R 580050 CDS YP_002968134.1 241190740 8008665 complement(828739..829485) 1 NC_012814.1 COG0532 Translation initiation factor 2 (IF-2; GTPase); hypothetical protein 829485 8008665 Balac_0699 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968134.1 828739 R 580050 CDS YP_002968135.1 241190741 8008666 complement(829626..831107) 1 NC_012814.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3 component, and related enzymes); dihydrolipoamide dehydrogenase 831107 8008666 Balac_0700 Bifidobacterium animalis subsp. lactis Bl-04 dihydrolipoamide dehydrogenase YP_002968135.1 829626 R 580050 CDS YP_002968136.1 241190742 8008667 complement(831328..831936) 1 NC_012814.1 hypothetical protein 831936 8008667 Balac_0701 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968136.1 831328 R 580050 CDS YP_002968137.1 241190743 8008668 832047..833414 1 NC_012814.1 COG0624 Acetylornithinedeacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; hypothetical protein 833414 8008668 Balac_0702 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968137.1 832047 D 580050 CDS YP_002968138.1 241190744 8008669 833653..834774 1 NC_012814.1 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 834774 8008669 Balac_0703 Bifidobacterium animalis subsp. lactis Bl-04 signal transduction histidine kinase YP_002968138.1 833653 D 580050 CDS YP_002968139.1 241190745 8008670 complement(834793..835233) 1 NC_012814.1 hypothetical protein 835233 8008670 Balac_0704 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968139.1 834793 R 580050 CDS YP_002968140.1 241190746 8008671 835339..835581 1 NC_012814.1 hypothetical protein 835581 8008671 Balac_0705 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968140.1 835339 D 580050 CDS YP_002968141.1 241190747 8008672 835977..836831 1 NC_012814.1 COG3409 Putative peptidoglycan-binding domain-containing protein; hypothetical protein 836831 8008672 Balac_0706 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968141.1 835977 D 580050 CDS YP_002968142.1 241190748 8008673 836812..836928 1 NC_012814.1 hypothetical protein 836928 8008673 Balac_0707 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968142.1 836812 D 580050 CDS YP_002968143.1 241190749 8008674 837273..838478 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 838478 8008674 Balac_0708 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968143.1 837273 D 580050 CDS YP_002968144.1 241190750 8008675 838514..838657 1 NC_012814.1 hypothetical protein 838657 8008675 Balac_0709 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968144.1 838514 D 580050 CDS YP_002968145.1 241190751 8008676 838893..839513 1 NC_012814.1 COG4721 Predicted membrane protein; hypothetical protein 839513 8008676 Balac_0710 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968145.1 838893 D 580050 CDS YP_002968146.1 241190752 8008677 839554..842109 1 NC_012814.1 COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 842109 8008677 Balac_0711 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968146.1 839554 D 580050 CDS YP_002968147.1 241190753 8008678 complement(842192..842911) 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 842911 8008678 Balac_0712 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002968147.1 842192 R 580050 CDS YP_002968148.1 241190754 8008679 complement(842949..844286) 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 844286 8008679 Balac_0713 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968148.1 842949 R 580050 CDS YP_002968149.1 241190755 8008680 complement(844383..844643) 1 NC_012814.1 transporter 844643 8008680 Balac_0714 Bifidobacterium animalis subsp. lactis Bl-04 transporter YP_002968149.1 844383 R 580050 CDS YP_002968150.1 241190756 8008681 844771..845676 1 NC_012814.1 COG0566 rRNA methylases; rRNA methylase 845676 8008681 Balac_0715 Bifidobacterium animalis subsp. lactis Bl-04 rRNA methylase YP_002968150.1 844771 D 580050 CDS YP_002968151.1 241190757 8008682 845755..846822 1 NC_012814.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 846822 pheS 8008682 pheS Bifidobacterium animalis subsp. lactis Bl-04 phenylalanyl-tRNA synthetase subunit alpha YP_002968151.1 845755 D 580050 CDS YP_002968152.1 241190758 8008683 846842..849433 1 NC_012814.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 849433 pheT 8008683 pheT Bifidobacterium animalis subsp. lactis Bl-04 phenylalanyl-tRNA synthetase subunit beta YP_002968152.1 846842 D 580050 CDS YP_002968153.1 241190759 8008684 849473..850261 1 NC_012814.1 hypothetical protein 850261 8008684 Balac_0718 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968153.1 849473 D 580050 CDS YP_002968154.1 241190760 8008685 850390..851484 1 NC_012814.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 851484 argC 8008685 argC Bifidobacterium animalis subsp. lactis Bl-04 N-acetyl-gamma-glutamyl-phosphate reductase YP_002968154.1 850390 D 580050 CDS YP_002968155.1 241190761 8008686 851481..852653 1 NC_012814.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 852653 argJ 8008686 argJ Bifidobacterium animalis subsp. lactis Bl-04 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_002968155.1 851481 D 580050 CDS YP_002968156.1 241190762 8008687 852663..853619 1 NC_012814.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 853619 8008687 Balac_0721 Bifidobacterium animalis subsp. lactis Bl-04 acetylglutamate kinase YP_002968156.1 852663 D 580050 CDS YP_002968157.1 241190763 8008688 853609..854862 1 NC_012814.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 854862 argD 8008688 argD Bifidobacterium animalis subsp. lactis Bl-04 acetylornithine aminotransferase YP_002968157.1 853609 D 580050 CDS YP_002968158.1 241190764 8008689 854946..855908 1 NC_012814.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 855908 8008689 Balac_0723 Bifidobacterium animalis subsp. lactis Bl-04 ornithine carbamoyltransferase YP_002968158.1 854946 D 580050 CDS YP_002968159.1 241190765 8008690 855928..856473 1 NC_012814.1 COG1438 Arginine repressor; arginine repressor ArgR 856473 8008690 Balac_0724 Bifidobacterium animalis subsp. lactis Bl-04 arginine repressor ArgR YP_002968159.1 855928 D 580050 CDS YP_002968160.1 241190766 8008691 856553..857791 1 NC_012814.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 857791 8008691 Balac_0725 Bifidobacterium animalis subsp. lactis Bl-04 argininosuccinate synthase YP_002968160.1 856553 D 580050 CDS YP_002968161.1 241190767 8008692 857906..859402 1 NC_012814.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 859402 8008692 Balac_0726 Bifidobacterium animalis subsp. lactis Bl-04 argininosuccinate lyase YP_002968161.1 857906 D 580050 CDS YP_002968162.1 241190768 8008693 complement(859486..860271) 1 NC_012814.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); L-2,3-butanediol dehydrogenase/acetoinreductase 860271 8008693 Balac_0727 Bifidobacterium animalis subsp. lactis Bl-04 L-2,3-butanediol dehydrogenase/acetoinreductase YP_002968162.1 859486 R 580050 CDS YP_002968163.1 241190769 8008694 860324..860911 1 NC_012814.1 COG1418 Predicted HD superfamily hydrolase; hypothetical protein 860911 8008694 Balac_0728 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968163.1 860324 D 580050 CDS YP_002968164.1 241190770 8008695 861000..862322 1 NC_012814.1 COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 862322 8008695 Balac_0729 Bifidobacterium animalis subsp. lactis Bl-04 tyrosyl-tRNA synthetase YP_002968164.1 861000 D 580050 CDS YP_002968165.1 241190771 8008696 862458..864125 1 NC_012814.1 hypothetical protein 864125 8008696 Balac_0730 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968165.1 862458 D 580050 CDS YP_002968166.1 241190772 8008697 864122..865162 1 NC_012814.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; hypothetical protein 865162 8008697 Balac_0731 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968166.1 864122 D 580050 CDS YP_002968167.1 241190773 8008698 865222..865980 1 NC_012814.1 COG1189 Predicted rRNA methylase; hemolysin-like protein 865980 8008698 Balac_0732 Bifidobacterium animalis subsp. lactis Bl-04 hemolysin-like protein YP_002968167.1 865222 D 580050 CDS YP_002968168.1 241190774 8008699 866238..867701 1 NC_012814.1 COG0168 Trk-type K+ transport systems, membrane components; hypothetical protein 867701 8008699 Balac_0733 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968168.1 866238 D 580050 CDS YP_002968169.1 241190775 8008700 867792..868442 1 NC_012814.1 COG0569 K+ transport systems, NAD-binding component; hypothetical protein 868442 8008700 Balac_0734 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968169.1 867792 D 580050 CDS YP_002968170.1 241190776 8008701 868532..869506 1 NC_012814.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 869506 ppnK 8008701 ppnK Bifidobacterium animalis subsp. lactis Bl-04 inorganic polyphosphate/ATP-NAD kinase YP_002968170.1 868532 D 580050 CDS YP_002968171.1 241190777 8008702 869631..871361 1 NC_012814.1 COG0497 ATPase involved in DNA repair; DNA repair protein RecN 871361 recN 8008702 recN Bifidobacterium animalis subsp. lactis Bl-04 DNA repair protein RecN YP_002968171.1 869631 D 580050 CDS YP_002968172.1 241190778 8008703 871373..872056 1 NC_012814.1 COG0637 Predicted phosphatase/phosphohexomutase; hydrolyase 872056 8008703 Balac_0737 Bifidobacterium animalis subsp. lactis Bl-04 hydrolyase YP_002968172.1 871373 D 580050 CDS YP_002968173.1 241190779 8008704 complement(872150..873637) 1 NC_012814.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 873637 8008704 Balac_0738 Bifidobacterium animalis subsp. lactis Bl-04 threonine synthase YP_002968173.1 872150 R 580050 CDS YP_002968174.1 241190780 8008705 873774..875087 1 NC_012814.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 875087 proA 8008705 proA Bifidobacterium animalis subsp. lactis Bl-04 gamma-glutamyl phosphate reductase YP_002968174.1 873774 D 580050 CDS YP_002968175.1 241190781 8008706 875105..875722 1 NC_012814.1 hypothetical protein 875722 8008706 Balac_0740 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968175.1 875105 D 580050 CDS YP_002968176.1 241190782 8008707 875719..876423 1 NC_012814.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 876423 nadD 8008707 nadD Bifidobacterium animalis subsp. lactis Bl-04 nicotinic acid mononucleotide adenylyltransferase YP_002968176.1 875719 D 580050 CDS YP_002968177.1 241190783 8008708 876515..877534 1 NC_012814.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 877534 8008708 Balac_0742 Bifidobacterium animalis subsp. lactis Bl-04 ribose-phosphate pyrophosphokinase YP_002968177.1 876515 D 580050 CDS YP_002968178.1 241190784 8009583 877758..879140 1 NC_012814.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 879140 glmU 8009583 glmU Bifidobacterium animalis subsp. lactis Bl-04 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002968178.1 877758 D 580050 CDS YP_002968179.1 241190785 8008710 879151..879555 1 NC_012814.1 COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 879555 8008710 Balac_0745 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968179.1 879151 D 580050 CDS YP_002968180.1 241190786 8008711 879619..880251 1 NC_012814.1 COG0406 Fructose-2,6-bisphosphatase; hypothetical protein 880251 8008711 Balac_0746 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968180.1 879619 D 580050 CDS YP_002968181.1 241190787 8008712 880351..881280 1 NC_012814.1 hypothetical protein 881280 8008712 Balac_0747 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968181.1 880351 D 580050 CDS YP_002968182.1 241190788 8009585 881751..882155 1 NC_012814.1 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase; hypothetical protein 882155 8009585 Balac_0750 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968182.1 881751 D 580050 CDS YP_002968183.1 241190789 8008714 882254..883078 1 NC_012814.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 883078 8008714 Balac_0751 Bifidobacterium animalis subsp. lactis Bl-04 phosphoglycerate mutase YP_002968183.1 882254 D 580050 CDS YP_002968184.1 241190790 8008715 883219..884169 1 NC_012814.1 COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter 884169 8008715 Balac_0752 Bifidobacterium animalis subsp. lactis Bl-04 Mg2+ and Co2+ transporter YP_002968184.1 883219 D 580050 CDS YP_002968185.1 241190791 8008716 884298..885068 1 NC_012814.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; solute binding protein of ABC transporter system 885068 8008716 Balac_0753 Bifidobacterium animalis subsp. lactis Bl-04 solute binding protein of ABC transporter system YP_002968185.1 884298 D 580050 CDS YP_002968186.1 241190792 8008717 885229..888120 1 NC_012814.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 888120 leuS 8008717 leuS Bifidobacterium animalis subsp. lactis Bl-04 leucyl-tRNA synthetase YP_002968186.1 885229 D 580050 CDS YP_002968187.1 241190793 8008718 888232..889008 1 NC_012814.1 COG1555 DNA uptake protein and related DNA-binding proteins; putative DNA-binding protein 889008 8008718 Balac_0755 Bifidobacterium animalis subsp. lactis Bl-04 putative DNA-binding protein YP_002968187.1 888232 D 580050 CDS YP_002968188.1 241190794 8008719 888990..890756 1 NC_012814.1 COG0658 Predicted membrane metal-binding protein; ComA-like putative transmembrane protein 890756 8008719 Balac_0756 Bifidobacterium animalis subsp. lactis Bl-04 ComA-like putative transmembrane protein YP_002968188.1 888990 D 580050 CDS YP_002968189.1 241190795 8008720 890822..891784 1 NC_012814.1 COG1466 DNA polymerase III, delta subunit; hypothetical protein 891784 8008720 Balac_0757 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968189.1 890822 D 580050 CDS YP_002968190.1 241190796 8008721 891781..892410 1 NC_012814.1 COG0802 Predicted ATPase or kinase; putative ATPase 892410 8008721 Balac_0758 Bifidobacterium animalis subsp. lactis Bl-04 putative ATPase YP_002968190.1 891781 D 580050 CDS YP_002968191.1 241190797 8008722 892486..893328 1 NC_012814.1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; hypothetical protein 893328 8008722 Balac_0759 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968191.1 892486 D 580050 CDS YP_002968192.1 241190798 8008723 893325..893822 1 NC_012814.1 COG0456 Acetyltransferases; Acetyltransferase 893822 8008723 Balac_0760 Bifidobacterium animalis subsp. lactis Bl-04 Acetyltransferase YP_002968192.1 893325 D 580050 CDS YP_002968193.1 241190799 8008724 893863..894906 1 NC_012814.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 894906 8008724 Balac_0761 Bifidobacterium animalis subsp. lactis Bl-04 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002968193.1 893863 D 580050 CDS YP_002968194.1 241190800 8009586 complement(895139..895645) 1 NC_012814.1 hypothetical protein 895645 8009586 Balac_0763 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968194.1 895139 R 580050 CDS YP_002968195.1 241190801 8009587 895975..896352 1 NC_012814.1 hypothetical protein 896352 8009587 Balac_0765 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968195.1 895975 D 580050 CDS YP_002968196.1 241190802 8008727 896587..897165 1 NC_012814.1 COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 897165 8008727 Balac_0766 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968196.1 896587 D 580050 CDS YP_002968197.1 241190803 8008728 complement(897186..898700) 1 NC_012814.1 COG4213 ABC-type xylose transport system, periplasmic component; hypothetical protein 898700 8008728 Balac_0767 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968197.1 897186 R 580050 CDS YP_002968198.1 241190804 8008729 complement(898816..900039) 1 NC_012814.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 900039 8008729 Balac_0768 Bifidobacterium animalis subsp. lactis Bl-04 isocitrate dehydrogenase YP_002968198.1 898816 R 580050 CDS YP_002968199.1 241190805 8008730 900166..901287 1 NC_012814.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 901287 8008730 Balac_0769 Bifidobacterium animalis subsp. lactis Bl-04 inosine 5-monophosphate dehydrogenase YP_002968199.1 900166 D 580050 CDS YP_002968200.1 241190806 8008731 901503..902084 1 NC_012814.1 hypothetical protein 902084 8008731 Balac_0770 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968200.1 901503 D 580050 CDS YP_002968201.1 241190807 8008732 902133..904154 1 NC_012814.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty acid CoA ligase 904154 8008732 Balac_0771 Bifidobacterium animalis subsp. lactis Bl-04 long-chain-fatty acid CoA ligase YP_002968201.1 902133 D 580050 CDS YP_002968202.1 241190808 8008733 904160..904642 1 NC_012814.1 COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase 904642 8008733 Balac_0772 Bifidobacterium animalis subsp. lactis Bl-04 N-formylmethionyl-tRNA deformylase YP_002968202.1 904160 D 580050 CDS YP_002968203.1 241190809 8008734 904919..905830 1 NC_012814.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 905830 rpsB 8008734 rpsB Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S2 YP_002968203.1 904919 D 580050 CDS YP_002968204.1 241190810 8008735 905940..906797 1 NC_012814.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 906797 tsf 8008735 tsf Bifidobacterium animalis subsp. lactis Bl-04 elongation factor Ts YP_002968204.1 905940 D 580050 CDS YP_002968205.1 241190811 8008736 906941..907687 1 NC_012814.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 907687 pyrH 8008736 pyrH Bifidobacterium animalis subsp. lactis Bl-04 uridylate kinase YP_002968205.1 906941 D 580050 CDS YP_002968206.1 241190812 8008737 907772..908293 1 NC_012814.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 908293 frr 8008737 frr Bifidobacterium animalis subsp. lactis Bl-04 ribosome recycling factor YP_002968206.1 907772 D 580050 CDS YP_002968207.1 241190813 8008738 908386..909354 1 NC_012814.1 COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase 909354 8008738 Balac_0777 Bifidobacterium animalis subsp. lactis Bl-04 CDP-diglyceride synthetase YP_002968207.1 908386 D 580050 CDS YP_002968208.1 241190814 8008739 909368..910564 1 NC_012814.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 910564 8008739 Balac_0778 Bifidobacterium animalis subsp. lactis Bl-04 ribosomal RNA large subunit methyltransferase N YP_002968208.1 909368 D 580050 CDS YP_002968209.1 241190815 8008740 910684..911253 1 NC_012814.1 COG1309 Transcriptional regulator; hypothetical protein 911253 8008740 Balac_0779 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968209.1 910684 D 580050 CDS YP_002968210.1 241190816 8008741 911354..911989 1 NC_012814.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATPase 911989 8008741 Balac_0780 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATPase YP_002968210.1 911354 D 580050 CDS YP_002968211.1 241190817 8008742 911997..912734 1 NC_012814.1 COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 912734 8008742 Balac_0781 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968211.1 911997 D 580050 CDS YP_002968212.1 241190818 8008743 912876..913646 1 NC_012814.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 913646 8008743 Balac_0782 Bifidobacterium animalis subsp. lactis Bl-04 imidazole glycerol phosphate synthase subunit HisF YP_002968212.1 912876 D 580050 CDS YP_002968213.1 241190819 8008744 913718..914131 1 NC_012814.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 914131 hisI 8008744 hisI Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosyl-AMP cyclohydrolase YP_002968213.1 913718 D 580050 CDS YP_002968214.1 241190820 8008745 914128..915693 1 NC_012814.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; Anthranilate/para-aminobenzoate synthases component I 915693 8008745 Balac_0784 Bifidobacterium animalis subsp. lactis Bl-04 Anthranilate/para-aminobenzoate synthases component I YP_002968214.1 914128 D 580050 CDS YP_002968215.1 241190821 8008746 complement(915773..916363) 1 NC_012814.1 COG1573 Uracil-DNA glycosylase; uracil-DNA glycosylase 916363 8008746 Balac_0785 Bifidobacterium animalis subsp. lactis Bl-04 uracil-DNA glycosylase YP_002968215.1 915773 R 580050 CDS YP_002968216.1 241190822 8008747 complement(916543..916692) 1 NC_012814.1 hypothetical protein 916692 8008747 Balac_0786 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968216.1 916543 R 580050 CDS YP_002968217.1 241190823 8008748 complement(916899..917204) 1 NC_012814.1 hypothetical protein 917204 8008748 Balac_0787 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968217.1 916899 R 580050 CDS YP_002968218.1 241190824 8008749 917455..919539 1 NC_012814.1 catalyzes ring closure to form indole-3-glycerol phosphate; catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta 919539 8008749 Balac_0788 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta YP_002968218.1 917455 D 580050 CDS YP_002968219.1 241190825 8008750 919565..920434 1 NC_012814.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 920434 trpA 8008750 trpA Bifidobacterium animalis subsp. lactis Bl-04 tryptophan synthase subunit alpha YP_002968219.1 919565 D 580050 CDS YP_002968220.1 241190826 8008751 920531..921469 1 NC_012814.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 921469 8008751 Balac_0790 Bifidobacterium animalis subsp. lactis Bl-04 prolipoprotein diacylglyceryl transferase YP_002968220.1 920531 D 580050 CDS YP_002968221.1 241190827 8008752 921524..922189 1 NC_012814.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 922189 8008752 Balac_0791 Bifidobacterium animalis subsp. lactis Bl-04 ribulose-phosphate 3-epimerase YP_002968221.1 921524 D 580050 CDS YP_002968222.1 241190828 8008753 922286..922549 1 NC_012814.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 922549 hisE 8008753 hisE Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosyl-ATP pyrophosphatase YP_002968222.1 922286 D 580050 CDS YP_002968223.1 241190829 8008754 922613..923464 1 NC_012814.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 923464 hisG 8008754 hisG Bifidobacterium animalis subsp. lactis Bl-04 ATP phosphoribosyltransferase YP_002968223.1 922613 D 580050 CDS YP_002968224.1 241190830 8008755 923485..924111 1 NC_012814.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3- phosphate3-phosphatidyl-transferase 924111 8008755 Balac_0794 Bifidobacterium animalis subsp. lactis Bl-04 CDP-diacylglycerol--glycerol-3- phosphate3-phosphatidyl-transferase YP_002968224.1 923485 D 580050 CDS YP_002968225.1 241190831 8008756 924271..925113 1 NC_012814.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 925113 8008756 Balac_0795 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968225.1 924271 D 580050 CDS YP_002968226.1 241190832 8008757 925113..925445 1 NC_012814.1 COG3856 Uncharacterized conserved protein (small basic protein); hypothetical protein 925445 8008757 Balac_0796 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968226.1 925113 D 580050 CDS YP_002968227.1 241190833 8008758 925448..926326 1 NC_012814.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 926326 8008758 Balac_0797 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968227.1 925448 D 580050 CDS YP_002968228.1 241190834 8008759 926333..926773 1 NC_012814.1 COG1716 FOG: FHA domain; hypothetical protein 926773 8008759 Balac_0798 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968228.1 926333 D 580050 CDS YP_002968229.1 241190835 8008760 926796..927527 1 NC_012814.1 COG0789 Predicted transcriptional regulators; SoxR-type transcriptional regulator 927527 8008760 Balac_0799 Bifidobacterium animalis subsp. lactis Bl-04 SoxR-type transcriptional regulator YP_002968229.1 926796 D 580050 CDS YP_002968230.1 241190836 8008761 927612..927965 1 NC_012814.1 hypothetical protein 927965 8008761 Balac_0800 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968230.1 927612 D 580050 CDS YP_002968231.1 241190837 8008762 927962..928339 1 NC_012814.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; CrcB protein 928339 8008762 Balac_0801 Bifidobacterium animalis subsp. lactis Bl-04 CrcB protein YP_002968231.1 927962 D 580050 CDS YP_002968232.1 241190838 8008763 928351..928728 1 NC_012814.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 928728 8008763 Balac_0802 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968232.1 928351 D 580050 CDS YP_002968233.1 241190839 8008764 complement(929281..930000) 1 NC_012814.1 COG0546 Predicted phosphatases; hydrolase or phosphatase 930000 8008764 Balac_0803 Bifidobacterium animalis subsp. lactis Bl-04 hydrolase or phosphatase YP_002968233.1 929281 R 580050 CDS YP_002968234.1 241190840 8008765 complement(930088..930435) 1 NC_012814.1 hypothetical protein 930435 8008765 Balac_0804 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968234.1 930088 R 580050 CDS YP_002968235.1 241190841 8008766 complement(930540..933029) 1 NC_012814.1 COG4581 Superfamily II RNA helicase; helicase 933029 8008766 Balac_0805 Bifidobacterium animalis subsp. lactis Bl-04 helicase YP_002968235.1 930540 R 580050 CDS YP_002968236.1 241190842 8008767 complement(933146..933463) 1 NC_012814.1 hypothetical protein 933463 8008767 Balac_0806 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968236.1 933146 R 580050 CDS YP_002968237.1 241190843 8008768 complement(933553..935490) 1 NC_012814.1 COG2378 Predicted transcriptional regulator; hypothetical protein 935490 8008768 Balac_0807 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968237.1 933553 R 580050 CDS YP_002968238.1 241190844 8008769 complement(935627..937054) 1 NC_012814.1 COG4284 UDP-glucose pyrophosphorylase; UTP-glucose-1-phosphate uridylyltransferase 937054 8008769 Balac_0808 Bifidobacterium animalis subsp. lactis Bl-04 UTP-glucose-1-phosphate uridylyltransferase YP_002968238.1 935627 R 580050 CDS YP_002968239.1 241190845 8009588 complement(937473..939605) 1 NC_012814.1 CMK catalyzes the formation of (d)CDP from ATP and (d)CMP; the function of the GTP-binding domain EngA appears to be in synchronizing cellular events by interacting with multiple cellular targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide-binding affinities in the two binding domains; bifunctional cytidylate kinase/GTP-binding protein 939605 8009588 Balac_0810 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional cytidylate kinase/GTP-binding protein YP_002968239.1 937473 R 580050 CDS YP_002968240.1 241190846 8008771 complement(939602..940375) 1 NC_012814.1 COG1187 16S rRNA uridine-516 pseudo uridylatesynthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudo uridylate synthase 940375 8008771 Balac_0811 Bifidobacterium animalis subsp. lactis Bl-04 16S rRNA uridine-516 pseudo uridylate synthase YP_002968240.1 939602 R 580050 CDS YP_002968241.1 241190847 8008772 940531..941553 1 NC_012814.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); membrane channel protein 941553 8008772 Balac_0812 Bifidobacterium animalis subsp. lactis Bl-04 membrane channel protein YP_002968241.1 940531 D 580050 CDS YP_002968242.1 241190848 8008773 complement(941467..941757) 1 NC_012814.1 hypothetical protein 941757 8008773 Balac_0813 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968242.1 941467 R 580050 CDS YP_002968243.1 241190849 8008774 complement(941912..943561) 1 NC_012814.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 943561 purH 8008774 purH Bifidobacterium animalis subsp. lactis Bl-04 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002968243.1 941912 R 580050 CDS YP_002968244.1 241190850 8008775 complement(943551..944909) 1 NC_012814.1 hypothetical protein 944909 8008775 Balac_0815 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968244.1 943551 R 580050 CDS YP_002968245.1 241190851 8008776 complement(944909..945826) 1 NC_012814.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 945826 8008776 Balac_0816 Bifidobacterium animalis subsp. lactis Bl-04 succinyl-CoA synthetase subunit alpha YP_002968245.1 944909 R 580050 CDS YP_002968246.1 241190852 8008777 complement(945827..947020) 1 NC_012814.1 COG0045 Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase subunit beta 947020 8008777 Balac_0817 Bifidobacterium animalis subsp. lactis Bl-04 Succinyl-CoA synthetase subunit beta YP_002968246.1 945827 R 580050 CDS YP_002968247.1 241190853 8008778 complement(947042..947623) 1 NC_012814.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 947623 8008778 Balac_0818 Bifidobacterium animalis subsp. lactis Bl-04 adenine phosphoribosyltransferase YP_002968247.1 947042 R 580050 CDS YP_002968248.1 241190854 8008779 complement(947667..948107) 1 NC_012814.1 COG1862 Preprotein translocase subunit YajC; hypothetical protein 948107 8008779 Balac_0819 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968248.1 947667 R 580050 CDS YP_002968249.1 241190855 8008780 complement(948161..949228) 1 NC_012814.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 949228 ruvB 8008780 ruvB Bifidobacterium animalis subsp. lactis Bl-04 Holliday junction DNA helicase RuvB YP_002968249.1 948161 R 580050 CDS YP_002968250.1 241190856 8008781 complement(949256..949879) 1 NC_012814.1 COG0632 Holliday junction resolvasome, DNA-binding subunit; holliday junction ATP-dependent DNA helicase ruvA 949879 8008781 Balac_0821 Bifidobacterium animalis subsp. lactis Bl-04 holliday junction ATP-dependent DNA helicase ruvA YP_002968250.1 949256 R 580050 CDS YP_002968251.1 241190857 8008782 complement(949917..950498) 1 NC_012814.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 950498 ruvC 8008782 ruvC Bifidobacterium animalis subsp. lactis Bl-04 Holliday junction resolvase YP_002968251.1 949917 R 580050 CDS YP_002968252.1 241190858 8008783 complement(950505..951260) 1 NC_012814.1 COG0217 Uncharacterized conserved protein; hypothetical protein 951260 8008783 Balac_0823 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968252.1 950505 R 580050 CDS YP_002968253.1 241190859 8008784 complement(951314..952483) 1 NC_012814.1 COG0438 Glycosyltransferase; glycosyltransferase 952483 8008784 Balac_0824 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968253.1 951314 R 580050 CDS YP_002968254.1 241190860 8008785 complement(952543..953538) 1 NC_012814.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 953538 8008785 Balac_0825 Bifidobacterium animalis subsp. lactis Bl-04 lipid A biosynthesis lauroyl acyltransferase YP_002968254.1 952543 R 580050 CDS YP_002968255.1 241190861 8008786 complement(953600..954271) 1 NC_012814.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate3- phosphatidyltransferase 954271 8008786 Balac_0826 Bifidobacterium animalis subsp. lactis Bl-04 CDP-diacylglycerol--glycerol-3-phosphate3- phosphatidyltransferase YP_002968255.1 953600 R 580050 CDS YP_002968256.1 241190862 8008787 complement(954430..956508) 1 NC_012814.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 956508 thrS 8008787 thrS Bifidobacterium animalis subsp. lactis Bl-04 threonyl-tRNA synthetase YP_002968256.1 954430 R 580050 CDS YP_002968257.1 241190863 8008788 complement(956725..957234) 1 NC_012814.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 957234 8008788 Balac_0828 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968257.1 956725 R 580050 CDS YP_002968258.1 241190864 8009589 957629..958150 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; transcriptional regulator 958150 8009589 Balac_0830 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968258.1 957629 D 580050 CDS YP_002968259.1 241190865 8008790 complement(958196..958375) 1 NC_012814.1 hypothetical protein 958375 8008790 Balac_0831 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968259.1 958196 R 580050 CDS YP_002968260.1 241190866 8008791 complement(958423..958785) 1 NC_012814.1 hypothetical protein 958785 8008791 Balac_0832 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968260.1 958423 R 580050 CDS YP_002968261.1 241190867 8009593 960042..960842 1 NC_012814.1 hypothetical protein 960842 8009593 Balac_0837 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968261.1 960042 D 580050 CDS YP_002968262.1 241190868 8008793 complement(960936..961823) 1 NC_012814.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 961823 8008793 Balac_0838 Bifidobacterium animalis subsp. lactis Bl-04 UDP pyrophosphate phosphatase YP_002968262.1 960936 R 580050 CDS YP_002968263.1 241190869 8008794 961997..962791 1 NC_012814.1 COG3001 Fructosamine-3-kinase; hypothetical protein 962791 8008794 Balac_0839 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968263.1 961997 D 580050 CDS YP_002968264.1 241190870 8008795 complement(962914..964062) 1 NC_012814.1 COG0484 DnaJ-class molecular chaperone withC-terminal Zn finger domain; DnaJ-class molecular chaperone 964062 dnaJ 8008795 dnaJ Bifidobacterium animalis subsp. lactis Bl-04 DnaJ-class molecular chaperone YP_002968264.1 962914 R 580050 CDS YP_002968265.1 241190871 8008796 complement(964131..965231) 1 NC_012814.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 965231 hrcA 8008796 hrcA Bifidobacterium animalis subsp. lactis Bl-04 heat-inducible transcription repressor YP_002968265.1 964131 R 580050 CDS YP_002968266.1 241190872 8008797 965448..967544 1 NC_012814.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 967544 8008797 Balac_0842 Bifidobacterium animalis subsp. lactis Bl-04 transketolase YP_002968266.1 965448 D 580050 CDS YP_002968267.1 241190873 8008798 967640..968746 1 NC_012814.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 968746 8008798 Balac_0843 Bifidobacterium animalis subsp. lactis Bl-04 transaldolase YP_002968267.1 967640 D 580050 CDS YP_002968268.1 241190874 8008799 complement(968834..969499) 1 NC_012814.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 969499 8008799 Balac_0844 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968268.1 968834 R 580050 CDS YP_002968269.1 241190875 8008800 complement(969483..970682) 1 NC_012814.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; class I and II aminotransferase 970682 8008800 Balac_0845 Bifidobacterium animalis subsp. lactis Bl-04 class I and II aminotransferase YP_002968269.1 969483 R 580050 CDS YP_002968270.1 241190876 8008801 complement(970682..971200) 1 NC_012814.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 971200 8008801 Balac_0846 Bifidobacterium animalis subsp. lactis Bl-04 AsnC family transcriptional regulator YP_002968270.1 970682 R 580050 CDS YP_002968271.1 241190877 8008802 complement(971254..972933) 1 NC_012814.1 in Corynebacterium glutamicum the aminotransferase can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; this protein contains a helix-turn-helix domain at the N-terminus; bifunctional HTH-domain containing protein/aminotransferase 972933 8008802 Balac_0847 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional HTH-domain containing protein/aminotransferase YP_002968271.1 971254 R 580050 CDS YP_002968272.1 241190878 8008803 complement(973044..973874) 1 NC_012814.1 COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 973874 8008803 Balac_0848 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968272.1 973044 R 580050 CDS YP_002968273.1 241190879 8008804 complement(973974..974222) 1 NC_012814.1 preprotein translocase subunit SecG 974222 secG 8008804 secG Bifidobacterium animalis subsp. lactis Bl-04 preprotein translocase subunit SecG YP_002968273.1 973974 R 580050 CDS YP_002968274.1 241190880 8008805 complement(974289..975101) 1 NC_012814.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 975101 tpiA 8008805 tpiA Bifidobacterium animalis subsp. lactis Bl-04 triosephosphate isomerase YP_002968274.1 974289 R 580050 CDS YP_002968275.1 241190881 8008806 complement(975195..976400) 1 NC_012814.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 976400 pgk 8008806 pgk Bifidobacterium animalis subsp. lactis Bl-04 phosphoglycerate kinase YP_002968275.1 975195 R 580050 CDS YP_002968276.1 241190882 8008807 complement(976522..977484) 1 NC_012814.1 COG1481 Uncharacterized protein conserved in bacteria; hypothetical protein 977484 8008807 Balac_0852 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968276.1 976522 R 580050 CDS YP_002968277.1 241190883 8008808 complement(977633..978565) 1 NC_012814.1 COG1660 Predicted P-loop-containing kinase; hypothetical protein 978565 8008808 Balac_0853 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968277.1 977633 R 580050 CDS YP_002968278.1 241190884 8008809 complement(978565..979491) 1 NC_012814.1 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 979491 8008809 Balac_0854 Bifidobacterium animalis subsp. lactis Bl-04 shikimate 5-dehydrogenase YP_002968278.1 978565 R 580050 CDS YP_002968279.1 241190885 8008810 complement(979622..982012) 1 NC_012814.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 982012 uvrC 8008810 uvrC Bifidobacterium animalis subsp. lactis Bl-04 excinuclease ABC subunit C YP_002968279.1 979622 R 580050 CDS YP_002968280.1 241190886 8008811 complement(982075..985035) 1 NC_012814.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 985035 uvrA 8008811 uvrA Bifidobacterium animalis subsp. lactis Bl-04 excinuclease ABC subunit A YP_002968280.1 982075 R 580050 CDS YP_002968281.1 241190887 8008812 985364..986329 1 NC_012814.1 hypothetical protein 986329 8008812 Balac_0857 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968281.1 985364 D 580050 CDS YP_002968282.1 241190888 8008813 986415..986942 1 NC_012814.1 COG3663 G:T/U mismatch-specific DNA glycosylase; G:T/U mismatch-specific DNA glycosylase 986942 8008813 Balac_0858 Bifidobacterium animalis subsp. lactis Bl-04 G:T/U mismatch-specific DNA glycosylase YP_002968282.1 986415 D 580050 CDS YP_002968283.1 241190889 8008814 986999..987628 1 NC_012814.1 COG0400 Predicted esterase; putative esterase 987628 8008814 Balac_0859 Bifidobacterium animalis subsp. lactis Bl-04 putative esterase YP_002968283.1 986999 D 580050 CDS YP_002968284.1 241190890 8008815 987618..989219 1 NC_012814.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 989219 8008815 Balac_0860 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968284.1 987618 D 580050 CDS YP_002968285.1 241190891 8008816 complement(989328..990398) 1 NC_012814.1 COG0053 Predicted Co/Zn/Cd cation transporters; cation transporter 990398 8008816 Balac_0861 Bifidobacterium animalis subsp. lactis Bl-04 cation transporter YP_002968285.1 989328 R 580050 CDS YP_002968286.1 241190892 8008817 complement(990449..991222) 1 NC_012814.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; putative carboxymuconolactone decarboxylase 991222 8008817 Balac_0862 Bifidobacterium animalis subsp. lactis Bl-04 putative carboxymuconolactone decarboxylase YP_002968286.1 990449 R 580050 CDS YP_002968287.1 241190893 8008818 complement(991343..992287) 1 NC_012814.1 COG3049 Penicillin V acylase and related amidases; bile salt hydrolase, choloylglycine hydrolase 992287 bsh 8008818 bsh Bifidobacterium animalis subsp. lactis Bl-04 bile salt hydrolase, choloylglycine hydrolase YP_002968287.1 991343 R 580050 CDS YP_002968288.1 241190894 8008819 992498..994309 1 NC_012814.1 COG0062 Uncharacterized conserved protein; hypothetical protein 994309 8008819 Balac_0864 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968288.1 992498 D 580050 CDS YP_002968289.1 241190895 8008820 994445..995002 1 NC_012814.1 COG0450 Peroxiredoxin; Peroxiredoxin 995002 8008820 Balac_0865 Bifidobacterium animalis subsp. lactis Bl-04 Peroxiredoxin YP_002968289.1 994445 D 580050 CDS YP_002968290.1 241190896 8008821 995021..996793 1 NC_012814.1 COG0492 Thioredoxin reductase; thioredoxin reductase-like protein 996793 8008821 Balac_0866 Bifidobacterium animalis subsp. lactis Bl-04 thioredoxin reductase-like protein YP_002968290.1 995021 D 580050 CDS YP_002968291.1 241190897 8008822 complement(996884..997810) 1 NC_012814.1 COG0583 Transcriptional regulator; fhu operon transcription regulator 997810 8008822 Balac_0867 Bifidobacterium animalis subsp. lactis Bl-04 fhu operon transcription regulator YP_002968291.1 996884 R 580050 CDS YP_002968292.1 241190898 8008823 complement(997879..998535) 1 NC_012814.1 COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase 998535 8008823 Balac_0868 Bifidobacterium animalis subsp. lactis Bl-04 alpha beta hydrolase YP_002968292.1 997879 R 580050 CDS YP_002968293.1 241190899 8008824 998689..999672 1 NC_012814.1 COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 999672 8008824 Balac_0869 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968293.1 998689 D 580050 CDS YP_002968294.1 241190900 8008825 1000100..1001008 1 NC_012814.1 COG1397 ADP-ribosylglycohydrolase; hydrolase 1001008 8008825 Balac_0870 Bifidobacterium animalis subsp. lactis Bl-04 hydrolase YP_002968294.1 1000100 D 580050 CDS YP_002968295.1 241190901 8008826 1001179..1001523 1 NC_012814.1 COG1733 Predicted transcriptional regulators; transcriptional regulator 1001523 8008826 Balac_0871 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968295.1 1001179 D 580050 CDS YP_002968296.1 241190902 8008827 1001706..1002239 1 NC_012814.1 hypothetical protein 1002239 8008827 Balac_0872 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968296.1 1001706 D 580050 CDS YP_002968297.1 241190903 8008828 complement(1002246..1002671) 1 NC_012814.1 COG0456 Acetyltransferases; acetyltransferase 1002671 8008828 Balac_0873 Bifidobacterium animalis subsp. lactis Bl-04 acetyltransferase YP_002968297.1 1002246 R 580050 CDS YP_002968298.1 241190904 8008829 complement(1003167..1003862) 1 NC_012814.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1003862 pyrE 8008829 pyrE Bifidobacterium animalis subsp. lactis Bl-04 orotate phosphoribosyltransferase YP_002968298.1 1003167 R 580050 CDS YP_002968299.1 241190905 8008830 complement(1004000..1004983) 1 NC_012814.1 COG0167 Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase 1004983 8008830 Balac_0875 Bifidobacterium animalis subsp. lactis Bl-04 Dihydroorotate dehydrogenase YP_002968299.1 1004000 R 580050 CDS YP_002968300.1 241190906 8008831 complement(1004976..1005815) 1 NC_012814.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; dihydroorotate dehydrogenase electron transfer subunit 1005815 8008831 Balac_0876 Bifidobacterium animalis subsp. lactis Bl-04 dihydroorotate dehydrogenase electron transfer subunit YP_002968300.1 1004976 R 580050 CDS YP_002968301.1 241190907 8008832 complement(1005883..1006833) 1 NC_012814.1 COG0284 Orotidine-5-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 1006833 8008832 Balac_0877 Bifidobacterium animalis subsp. lactis Bl-04 orotidine 5'-phosphate decarboxylase YP_002968301.1 1005883 R 580050 CDS YP_002968302.1 241190908 8008833 complement(1006839..1008263) 1 NC_012814.1 COG0044 Dihydroorotase and related cyclicamidohydrolases; dihydroorotase 1008263 8008833 Balac_0878 Bifidobacterium animalis subsp. lactis Bl-04 dihydroorotase YP_002968302.1 1006839 R 580050 CDS YP_002968303.1 241190909 8008834 complement(1008264..1008683) 1 NC_012814.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 1008683 8008834 Balac_0879 Bifidobacterium animalis subsp. lactis Bl-04 aspartate carbamoyltransferase YP_002968303.1 1008264 R 580050 CDS YP_002968304.1 241190910 8008835 complement(1008683..1009642) 1 NC_012814.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1009642 pyrB 8008835 pyrB Bifidobacterium animalis subsp. lactis Bl-04 aspartate carbamoyltransferase YP_002968304.1 1008683 R 580050 CDS YP_002968305.1 241190911 8008836 complement(1009772..1010254) 1 NC_012814.1 hypothetical protein 1010254 8008836 Balac_0881 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968305.1 1009772 R 580050 CDS YP_002968306.1 241190912 8008837 complement(1010270..1013404) 1 NC_012814.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1013404 8008837 Balac_0882 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002968306.1 1010270 R 580050 CDS YP_002968307.1 241190913 8008838 complement(1013447..1014283) 1 NC_012814.1 COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 1014283 8008838 Balac_0883 Bifidobacterium animalis subsp. lactis Bl-04 5,10-methylenetetrahydrofolate reductase YP_002968307.1 1013447 R 580050 CDS YP_002968308.1 241190914 8008839 complement(1014430..1016733) 1 NC_012814.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1016733 8008839 Balac_0884 Bifidobacterium animalis subsp. lactis Bl-04 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_002968308.1 1014430 R 580050 CDS YP_002968309.1 241190915 8008840 complement(1016880..1017434) 1 NC_012814.1 COG2062 Phosphohistidine phosphatase SixA; hypothetical protein 1017434 8008840 Balac_0885 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968309.1 1016880 R 580050 CDS YP_002968310.1 241190916 8008841 complement(1017535..1018593) 1 NC_012814.1 COG2519 tRNA (1-methyladenosine methyltransferase and related methyltransferases); hypothetical protein 1018593 8008841 Balac_0886 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968310.1 1017535 R 580050 CDS YP_002968311.1 241190917 8008842 complement(1018691..1019533) 1 NC_012814.1 COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; ABC transporter ATP-binding protein 1019533 8008842 Balac_0887 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968311.1 1018691 R 580050 CDS YP_002968312.1 241190918 8008843 complement(1019607..1020866) 1 NC_012814.1 COG0438 Glycosyltransferase; glycosyltransferase 1020866 8008843 Balac_0888 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968312.1 1019607 R 580050 CDS YP_002968313.1 241190919 8008844 1021103..1021588 1 NC_012814.1 COG1225 Peroxiredoxin; thioredoxin peroxidase 1021588 8008844 Balac_0889 Bifidobacterium animalis subsp. lactis Bl-04 thioredoxin peroxidase YP_002968313.1 1021103 D 580050 CDS YP_002968314.1 241190920 8008845 complement(1021672..1022130) 1 NC_012814.1 hypothetical protein 1022130 8008845 Balac_0890 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968314.1 1021672 R 580050 CDS YP_002968315.1 241190921 8008846 complement(1022274..1023809) 1 NC_012814.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 1023809 gltD 8008846 gltD Bifidobacterium animalis subsp. lactis Bl-04 glutamate synthase subunit beta YP_002968315.1 1022274 R 580050 CDS YP_002968316.1 241190922 8008847 complement(1023811..1028331) 1 NC_012814.1 COG0067 Glutamate synthase domain 1; Glutamate synthase 1028331 8008847 Balac_0892 Bifidobacterium animalis subsp. lactis Bl-04 Glutamate synthase YP_002968316.1 1023811 R 580050 CDS YP_002968317.1 241190923 8008848 complement(1028604..1029917) 1 NC_012814.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Coproporphyrinogen III oxidase 1029917 8008848 Balac_0893 Bifidobacterium animalis subsp. lactis Bl-04 Coproporphyrinogen III oxidase YP_002968317.1 1028604 R 580050 CDS YP_002968318.1 241190924 8008849 complement(1029925..1031805) 1 NC_012814.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1031805 8008849 Balac_0894 Bifidobacterium animalis subsp. lactis Bl-04 GTP-binding protein LepA YP_002968318.1 1029925 R 580050 CDS YP_002968319.1 241190925 8008850 1031953..1032213 1 NC_012814.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1032213 rpsT 8008850 rpsT Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S20 YP_002968319.1 1031953 D 580050 CDS YP_002968320.1 241190926 8008851 complement(1032304..1033089) 1 NC_012814.1 COG2860 Predicted membrane protein; hypothetical protein 1033089 8008851 Balac_0896 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968320.1 1032304 R 580050 CDS YP_002968321.1 241190927 8008852 complement(1033209..1034336) 1 NC_012814.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1034336 8008852 Balac_0897 Bifidobacterium animalis subsp. lactis Bl-04 branched-chain amino acid aminotransferase YP_002968321.1 1033209 R 580050 CDS YP_002968322.1 241190928 8008853 complement(1034550..1035176) 1 NC_012814.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1035176 8008853 Balac_0898 Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L25 YP_002968322.1 1034550 R 580050 CDS YP_002968323.1 241190929 8008854 1035422..1036423 1 NC_012814.1 COG1073 Hydrolases of the alpha/beta superfamily; putative alpha/beta superfamily hydrolase 1036423 8008854 Balac_0899 Bifidobacterium animalis subsp. lactis Bl-04 putative alpha/beta superfamily hydrolase YP_002968323.1 1035422 D 580050 CDS YP_002968324.1 241190930 8008855 complement(1036533..1037948) 1 NC_012814.1 COG1282 NAD/NADP transhydrogenase beta subunit; NAD/NADP transhydrogenase subunit beta 1037948 8008855 Balac_0900 Bifidobacterium animalis subsp. lactis Bl-04 NAD/NADP transhydrogenase subunit beta YP_002968324.1 1036533 R 580050 CDS YP_002968325.1 241190931 8008856 complement(1037948..1038265) 1 NC_012814.1 COG3288 NAD/NADP transhydrogenase alpha subunit; NAD/NADP transhydrogenase subunit alpha 1038265 8008856 Balac_0901 Bifidobacterium animalis subsp. lactis Bl-04 NAD/NADP transhydrogenase subunit alpha YP_002968325.1 1037948 R 580050 CDS YP_002968326.1 241190932 8008857 complement(1038262..1039416) 1 NC_012814.1 COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha part 1 1039416 8008857 Balac_0902 Bifidobacterium animalis subsp. lactis Bl-04 NAD(P) transhydrogenase subunit alpha part 1 YP_002968326.1 1038262 R 580050 CDS YP_002968327.1 241190933 8008858 1039683..1041743 1 NC_012814.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty-acid-CoA ligase 1041743 8008858 Balac_0903 Bifidobacterium animalis subsp. lactis Bl-04 long-chain-fatty-acid-CoA ligase YP_002968327.1 1039683 D 580050 CDS YP_002968328.1 241190934 8008859 complement(1041817..1042812) 1 NC_012814.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1042812 era 8008859 era Bifidobacterium animalis subsp. lactis Bl-04 GTP-binding protein Era YP_002968328.1 1041817 R 580050 CDS YP_002968329.1 241190935 8008860 complement(1042814..1044202) 1 NC_012814.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 1044202 8008860 Balac_0905 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968329.1 1042814 R 580050 CDS YP_002968330.1 241190936 8008861 complement(1044220..1044765) 1 NC_012814.1 COG0319 Predicted metal-dependent hydrolase; putative metalloprotease 1044765 8008861 Balac_0906 Bifidobacterium animalis subsp. lactis Bl-04 putative metalloprotease YP_002968330.1 1044220 R 580050 CDS YP_002968331.1 241190937 8008862 complement(1044755..1045918) 1 NC_012814.1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; PhoH-like protein 1045918 8008862 Balac_0907 Bifidobacterium animalis subsp. lactis Bl-04 PhoH-like protein YP_002968331.1 1044755 R 580050 CDS YP_002968332.1 241190938 8008863 complement(1045973..1046308) 1 NC_012814.1 COG0537 Diadenosine tetraphosphate (Ap4A hydrolase and other HIT family hydrolases); hypothetical protein 1046308 8008863 Balac_0908 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968332.1 1045973 R 580050 CDS YP_002968333.1 241190939 8008864 complement(1046400..1047197) 1 NC_012814.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1047197 8008864 Balac_0909 Bifidobacterium animalis subsp. lactis Bl-04 16S ribosomal RNA methyltransferase RsmE YP_002968333.1 1046400 R 580050 CDS YP_002968334.1 241190940 8009594 1047483..1048355 1 NC_012814.1 COG0566 rRNA methylases; tRNA/rRNA methyltransferase 1048355 8009594 Balac_0911 Bifidobacterium animalis subsp. lactis Bl-04 tRNA/rRNA methyltransferase YP_002968334.1 1047483 D 580050 CDS YP_002968335.1 241190941 8008866 complement(1048450..1049112) 1 NC_012814.1 transposase 1049112 8008866 Balac_0912 Bifidobacterium animalis subsp. lactis Bl-04 transposase YP_002968335.1 1048450 R 580050 CDS YP_002968336.1 241190942 8008867 1049379..1050626 1 NC_012814.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1050626 glgC 8008867 glgC Bifidobacterium animalis subsp. lactis Bl-04 glucose-1-phosphate adenylyltransferase YP_002968336.1 1049379 D 580050 CDS YP_002968337.1 241190943 8008868 complement(1050704..1051276) 1 NC_012814.1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; hypothetical protein 1051276 8008868 Balac_0914 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968337.1 1050704 R 580050 CDS YP_002968338.1 241190944 8008869 complement(1051278..1051853) 1 NC_012814.1 COG0822 NifU homolog involved in Fe-S cluster formation; hypothetical protein 1051853 8008869 Balac_0915 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968338.1 1051278 R 580050 CDS YP_002968339.1 241190945 8008870 complement(1051943..1053214) 1 NC_012814.1 COG0520 Selenocysteine lyase; NifS-like aminotransferase 1053214 8008870 Balac_0916 Bifidobacterium animalis subsp. lactis Bl-04 NifS-like aminotransferase YP_002968339.1 1051943 R 580050 CDS YP_002968340.1 241190946 8008871 complement(1053245..1054024) 1 NC_012814.1 COG0396 ABC-type transport system involved in Fe-Scluster assembly, ATPase component; ABC transporter ATP-binding protein 1054024 8008871 Balac_0917 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968340.1 1053245 R 580050 CDS YP_002968341.1 241190947 8008872 complement(1054024..1055250) 1 NC_012814.1 COG0719 ABC-type transport system involved in Fe-Scluster assembly, permease component; ABC-type transport system for Fe-S cluster assembly permease 1055250 8008872 Balac_0918 Bifidobacterium animalis subsp. lactis Bl-04 ABC-type transport system for Fe-S cluster assembly permease YP_002968341.1 1054024 R 580050 CDS YP_002968342.1 241190948 8008873 complement(1055254..1056750) 1 NC_012814.1 COG0719 ABC-type transport system involved in Fe-Scluster assembly, permease component; ABC-type transport system for Fe-S cluster assembly permease 1056750 8008873 Balac_0919 Bifidobacterium animalis subsp. lactis Bl-04 ABC-type transport system for Fe-S cluster assembly permease YP_002968342.1 1055254 R 580050 CDS YP_002968343.1 241190949 8008874 complement(1056957..1058624) 1 NC_012814.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 1058624 8008874 Balac_0920 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968343.1 1056957 R 580050 CDS YP_002968344.1 241190950 8008875 complement(1058621..1058722) 1 NC_012814.1 hypothetical protein 1058722 8008875 Balac_0921 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968344.1 1058621 R 580050 CDS YP_002968345.1 241190951 8008876 complement(1058770..1060317) 1 NC_012814.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1060317 pyrG 8008876 pyrG Bifidobacterium animalis subsp. lactis Bl-04 CTP synthetase YP_002968345.1 1058770 R 580050 CDS YP_002968346.1 241190952 8008877 complement(1060583..1061131) 1 NC_012814.1 hypothetical protein 1061131 8008877 Balac_0923 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968346.1 1060583 R 580050 CDS YP_002968347.1 241190953 8008878 complement(1061177..1062157) 1 NC_012814.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; pullulanase 1062157 8008878 Balac_0924 Bifidobacterium animalis subsp. lactis Bl-04 pullulanase YP_002968347.1 1061177 R 580050 CDS YP_002968348.1 241190954 8008879 1063260..1063430 1 NC_012814.1 hypothetical protein 1063430 8008879 Balac_0925 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968348.1 1063260 D 580050 CDS YP_002968349.1 241190955 8008880 complement(1063454..1063570) 1 NC_012814.1 hypothetical protein 1063570 8008880 Balac_0926 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968349.1 1063454 R 580050 CDS YP_002968350.1 241190956 8008881 complement(1063871..1064560) 1 NC_012814.1 hypothetical protein 1064560 8008881 Balac_0927 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968350.1 1063871 R 580050 CDS YP_002968351.1 241190957 8008882 complement(1064578..1065780) 1 NC_012814.1 hypothetical protein 1065780 8008882 Balac_0928 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968351.1 1064578 R 580050 CDS YP_002968352.1 241190958 8008883 complement(1065815..1066984) 1 NC_012814.1 hypothetical protein 1066984 8008883 Balac_0929 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968352.1 1065815 R 580050 CDS YP_002968353.1 241190959 8008884 1067152..1067577 1 NC_012814.1 hypothetical protein 1067577 8008884 Balac_0930 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968353.1 1067152 D 580050 CDS YP_002968354.1 241190960 8008885 1067882..1068334 1 NC_012814.1 hypothetical protein 1068334 8008885 Balac_0931 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968354.1 1067882 D 580050 CDS YP_002968355.1 241190961 8008886 1068375..1069340 1 NC_012814.1 hypothetical protein 1069340 8008886 Balac_0932 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968355.1 1068375 D 580050 CDS YP_002968356.1 241190962 8008887 complement(1069462..1069926) 1 NC_012814.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1069926 8008887 Balac_0933 Bifidobacterium animalis subsp. lactis Bl-04 3-dehydroquinate dehydratase YP_002968356.1 1069462 R 580050 CDS YP_002968357.1 241190963 8008888 complement(1070052..1071707) 1 NC_012814.1 catalyzes the formation of shikimate 3-phosphate from shikimate and the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; bifunctional shikimate kinase/3-dehydroquinate synthase 1071707 aroB 8008888 aroB Bifidobacterium animalis subsp. lactis Bl-04 bifunctional shikimate kinase/3-dehydroquinate synthase YP_002968357.1 1070052 R 580050 CDS YP_002968358.1 241190964 8008889 complement(1071721..1072911) 1 NC_012814.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1072911 8008889 Balac_0935 Bifidobacterium animalis subsp. lactis Bl-04 chorismate synthase YP_002968358.1 1071721 R 580050 CDS YP_002968359.1 241190965 8008890 1072983..1073441 1 NC_012814.1 hypothetical protein 1073441 8008890 Balac_0936 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968359.1 1072983 D 580050 CDS YP_002968360.1 241190966 8008891 complement(1073492..1074673) 1 NC_012814.1 COG1559 Predicted periplasmic solute-binding protein; hypothetical protein 1074673 8008891 Balac_0937 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968360.1 1073492 R 580050 CDS YP_002968361.1 241190967 8008892 complement(1074675..1075166) 1 NC_012814.1 COG0816 Predicted endonuclease involved inrecombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); putative endonuclease for recombination 1075166 8008892 Balac_0938 Bifidobacterium animalis subsp. lactis Bl-04 putative endonuclease for recombination YP_002968361.1 1074675 R 580050 CDS YP_002968362.1 241190968 8008893 complement(1075166..1077865) 1 NC_012814.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1077865 alaS 8008893 alaS Bifidobacterium animalis subsp. lactis Bl-04 alanyl-tRNA synthetase YP_002968362.1 1075166 R 580050 CDS YP_002968363.1 241190969 8008894 complement(1077921..1078157) 1 NC_012814.1 hypothetical protein 1078157 8008894 Balac_0940 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968363.1 1077921 R 580050 CDS YP_002968364.1 241190970 8008895 complement(1078157..1078558) 1 NC_012814.1 hypothetical protein 1078558 8008895 Balac_0941 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968364.1 1078157 R 580050 CDS YP_002968365.1 241190971 8008896 complement(1078633..1079310) 1 NC_012814.1 COG0406 Fructose-2,6-bisphosphatase; hypothetical protein 1079310 8008896 Balac_0942 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968365.1 1078633 R 580050 CDS YP_002968366.1 241190972 8008897 1079384..1079749 1 NC_012814.1 COG1950 Predicted membrane protein; hypothetical protein 1079749 8008897 Balac_0943 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968366.1 1079384 D 580050 CDS YP_002968367.1 241190973 8008898 complement(1079853..1080473) 1 NC_012814.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1080473 rpsD 8008898 rpsD Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S4 YP_002968367.1 1079853 R 580050 CDS YP_002968368.1 241190974 8008899 complement(1080703..1083522) 1 NC_012814.1 COG0210 Superfamily I DNA and RNA helicases; Superfamily I DNA and RNA helicase 1083522 8008899 Balac_0945 Bifidobacterium animalis subsp. lactis Bl-04 Superfamily I DNA and RNA helicase YP_002968368.1 1080703 R 580050 CDS YP_002968369.1 241190975 8008900 1083604..1084185 1 NC_012814.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1084185 8008900 Balac_0946 Bifidobacterium animalis subsp. lactis Bl-04 xanthine phosphoribosyltransferase YP_002968369.1 1083604 D 580050 CDS YP_002968370.1 241190976 8008901 1084330..1085799 1 NC_012814.1 COG2233 Xanthine/uracil permeases; Xanthine/uracil permease 1085799 8008901 Balac_0947 Bifidobacterium animalis subsp. lactis Bl-04 Xanthine/uracil permease YP_002968370.1 1084330 D 580050 CDS YP_002968371.1 241190977 8008902 1086006..1086851 1 NC_012814.1 hypothetical protein 1086851 8008902 Balac_0948 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968371.1 1086006 D 580050 CDS YP_002968372.1 241190978 8008903 1086875..1087129 1 NC_012814.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; class II aminotransferase 1087129 8008903 Balac_0949 Bifidobacterium animalis subsp. lactis Bl-04 class II aminotransferase YP_002968372.1 1086875 D 580050 CDS YP_002968373.1 241190979 8008904 1087119..1088069 1 NC_012814.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional beta-cystathionase/maltose regulonrepressor 1088069 8008904 Balac_0950 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional beta-cystathionase/maltose regulonrepressor YP_002968373.1 1087119 D 580050 CDS YP_002968374.1 241190980 8008905 complement(1088066..1088923) 1 NC_012814.1 hypothetical protein 1088923 8008905 Balac_0951 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968374.1 1088066 R 580050 CDS YP_002968375.1 241190981 8008906 complement(1089165..1090637) 1 NC_012814.1 COG0366 Glycosidases; cytoplasmic alpha-amylase 1090637 8008906 Balac_0952 Bifidobacterium animalis subsp. lactis Bl-04 cytoplasmic alpha-amylase YP_002968375.1 1089165 R 580050 CDS YP_002968376.1 241190982 8008907 complement(1090788..1091426) 1 NC_012814.1 COG2071 Predicted glutamine amidotransferases; amidotransferase subunit 1091426 8008907 Balac_0953 Bifidobacterium animalis subsp. lactis Bl-04 amidotransferase subunit YP_002968376.1 1090788 R 580050 CDS YP_002968377.1 241190983 8008908 complement(1091666..1092145) 1 NC_012814.1 COG3760 Uncharacterized conserved protein; prolyl-tRNA synthetase 1092145 8008908 Balac_0954 Bifidobacterium animalis subsp. lactis Bl-04 prolyl-tRNA synthetase YP_002968377.1 1091666 R 580050 CDS YP_002968378.1 241190984 8008909 complement(1092243..1092863) 1 NC_012814.1 hypothetical protein 1092863 8008909 Balac_0955 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968378.1 1092243 R 580050 CDS YP_002968379.1 241190985 8008910 complement(1092860..1093738) 1 NC_012814.1 COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein 1093738 8008910 Balac_0956 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968379.1 1092860 R 580050 CDS YP_002968380.1 241190986 8008911 complement(1093735..1094271) 1 NC_012814.1 COG1725 Predicted transcriptional regulators; hypothetical protein 1094271 8008911 Balac_0957 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968380.1 1093735 R 580050 CDS YP_002968381.1 241190987 8008912 1094496..1095503 1 NC_012814.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 1095503 8008912 Balac_0958 Bifidobacterium animalis subsp. lactis Bl-04 XRE family transcriptional regulator YP_002968381.1 1094496 D 580050 CDS YP_002968382.1 241190988 8008913 1095571..1096596 1 NC_012814.1 COG1816 Adenosine deaminase; adenosine deaminase 1096596 8008913 Balac_0959 Bifidobacterium animalis subsp. lactis Bl-04 adenosine deaminase YP_002968382.1 1095571 D 580050 CDS YP_002968383.1 241190989 8008914 complement(1096597..1097307) 1 NC_012814.1 putative cytoplasmic protein 1097307 8008914 Balac_0960 Bifidobacterium animalis subsp. lactis Bl-04 putative cytoplasmic protein YP_002968383.1 1096597 R 580050 CDS YP_002968384.1 241190990 8008915 1097593..1097898 1 NC_012814.1 COG1605 Chorismate mutase; chorismate mutase 1097898 8008915 Balac_0961 Bifidobacterium animalis subsp. lactis Bl-04 chorismate mutase YP_002968384.1 1097593 D 580050 CDS YP_002968385.1 241190991 8008916 1098244..1098822 1 NC_012814.1 hypothetical protein 1098822 8008916 Balac_0962 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968385.1 1098244 D 580050 CDS YP_002968386.1 241190992 8008917 complement(1098835..1099056) 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 1099056 8008917 Balac_0963 Bifidobacterium animalis subsp. lactis Bl-04 GCN5-like N-acetyltransferase YP_002968386.1 1098835 R 580050 CDS YP_002968387.1 241190993 8008918 complement(1099196..1099768) 1 NC_012814.1 COG0563 Adenylate kinase and related kinases; putative adenylate kinase DNA topology modulator 1099768 8008918 Balac_0964 Bifidobacterium animalis subsp. lactis Bl-04 putative adenylate kinase DNA topology modulator YP_002968387.1 1099196 R 580050 CDS YP_002968388.1 241190994 8008919 1100062..1100349 1 NC_012814.1 COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 1100349 8008919 Balac_0965 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968388.1 1100062 D 580050 CDS YP_002968389.1 241190995 8008920 1100519..1100614 1 NC_012814.1 hypothetical protein 1100614 8008920 Balac_0966 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968389.1 1100519 D 580050 CDS YP_002968390.1 241190996 8008921 complement(1100953..1102872) 1 NC_012814.1 COG0480 Translation elongation factors (GTPases); ribosomal protection tetracycline resistance protein 1102872 8008921 Balac_0967 Bifidobacterium animalis subsp. lactis Bl-04 ribosomal protection tetracycline resistance protein YP_002968390.1 1100953 R 580050 CDS YP_002968391.1 241190997 8008922 complement(1103221..1104186) 1 NC_012814.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase, IS4 family protein 1104186 8008922 Balac_0968 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS4 family protein YP_002968391.1 1103221 R 580050 CDS YP_002968392.1 241190998 8008923 1104217..1104618 1 NC_012814.1 COG0107 Imidazoleglycerol-phosphate synthase; hypothetical protein 1104618 8008923 Balac_0969 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968392.1 1104217 D 580050 CDS YP_002968393.1 241190999 8008924 complement(1104814..1106376) 1 NC_012814.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1106376 guaA 8008924 guaA Bifidobacterium animalis subsp. lactis Bl-04 GMP synthase YP_002968393.1 1104814 R 580050 CDS YP_002968394.1 241191000 8008925 1106856..1109333 1 NC_012814.1 COG3957 Phosphoketolase; putative phosphoketolase 1109333 8008925 Balac_0971 Bifidobacterium animalis subsp. lactis Bl-04 putative phosphoketolase YP_002968394.1 1106856 D 580050 CDS YP_002968395.1 241191001 8008926 1109574..1111256 1 NC_012814.1 COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase 1111256 8008926 Balac_0972 Bifidobacterium animalis subsp. lactis Bl-04 phosphate acetyltransferase YP_002968395.1 1109574 D 580050 CDS YP_002968396.1 241191002 8008927 1111397..1112644 1 NC_012814.1 COG0282 Acetate kinase; acetate kinase 1112644 8008927 Balac_0973 Bifidobacterium animalis subsp. lactis Bl-04 acetate kinase YP_002968396.1 1111397 D 580050 CDS YP_002968397.1 241191003 8008928 complement(1112719..1114065) 1 NC_012814.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1114065 8008928 Balac_0974 Bifidobacterium animalis subsp. lactis Bl-04 3-phosphoshikimate 1-carboxyvinyltransferase YP_002968397.1 1112719 R 580050 CDS YP_002968398.1 241191004 8009595 1114373..1115602 1 NC_012814.1 hypothetical protein 1115602 8009595 Balac_0976 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968398.1 1114373 D 580050 CDS YP_002968399.1 241191005 8008930 complement(1115665..1117782) 1 NC_012814.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX 1117782 8008930 Balac_0977 Bifidobacterium animalis subsp. lactis Bl-04 glycogen operon protein GlgX YP_002968399.1 1115665 R 580050 CDS YP_002968400.1 241191006 8008931 complement(1117855..1118508) 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase 1118508 8008931 Balac_0978 Bifidobacterium animalis subsp. lactis Bl-04 NTP pyrophosphohydrolase YP_002968400.1 1117855 R 580050 CDS YP_002968401.1 241191007 8008932 complement(1118512..1119447) 1 NC_012814.1 COG0327 Uncharacterized conserved protein; hypothetical protein 1119447 8008932 Balac_0979 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968401.1 1118512 R 580050 CDS YP_002968402.1 241191008 8008933 complement(1119482..1122364) 1 NC_012814.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1122364 8008933 Balac_0980 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase I YP_002968402.1 1119482 R 580050 CDS YP_002968403.1 241191009 8008934 complement(1122444..1123202) 1 NC_012814.1 COG3707 Response regulator with putative antiterminator output domain; putative response regulator 1123202 8008934 Balac_0981 Bifidobacterium animalis subsp. lactis Bl-04 putative response regulator YP_002968403.1 1122444 R 580050 CDS YP_002968404.1 241191010 8008935 complement(1123335..1123964) 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase 1123964 8008935 Balac_0982 Bifidobacterium animalis subsp. lactis Bl-04 NTP pyrophosphohydrolase YP_002968404.1 1123335 R 580050 CDS YP_002968405.1 241191011 8009596 complement(1124321..1125682) 1 NC_012814.1 COG0469 Pyruvate kinase; pyruvate kinase 1125682 8009596 Balac_0984 Bifidobacterium animalis subsp. lactis Bl-04 pyruvate kinase YP_002968405.1 1124321 R 580050 CDS YP_002968406.1 241191012 8008937 complement(1125931..1126920) 1 NC_012814.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; putative tellurium resistance membrane protein 1126920 8008937 Balac_0985 Bifidobacterium animalis subsp. lactis Bl-04 putative tellurium resistance membrane protein YP_002968406.1 1125931 R 580050 CDS YP_002968407.1 241191013 8008938 complement(1126983..1129094) 1 NC_012814.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1129094 8008938 Balac_0986 Bifidobacterium animalis subsp. lactis Bl-04 excinuclease ABC subunit B YP_002968407.1 1126983 R 580050 CDS YP_002968408.1 241191014 8008939 complement(1129103..1129744) 1 NC_012814.1 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 1129744 8008939 Balac_0987 Bifidobacterium animalis subsp. lactis Bl-04 dephospho-CoA kinase YP_002968408.1 1129103 R 580050 CDS YP_002968409.1 241191015 8008940 complement(1129855..1131336) 1 NC_012814.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1131336 rpsA 8008940 rpsA Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S1 YP_002968409.1 1129855 R 580050 CDS YP_002968410.1 241191016 8008941 complement(1131508..1132401) 1 NC_012814.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1132401 8008941 Balac_0989 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002968410.1 1131508 R 580050 CDS YP_002968411.1 241191017 8008942 1132509..1133513 1 NC_012814.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; ABC transporter substrate-binding protein 1133513 8008942 Balac_0990 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002968411.1 1132509 D 580050 CDS YP_002968412.1 241191018 8008943 1133654..1134565 1 NC_012814.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn2+/Zn2+ ABC transporter ATPase 1134565 8008943 Balac_0991 Bifidobacterium animalis subsp. lactis Bl-04 Mn2+/Zn2+ ABC transporter ATPase YP_002968412.1 1133654 D 580050 CDS YP_002968413.1 241191019 8008944 1134562..1135407 1 NC_012814.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease 1135407 8008944 Balac_0992 Bifidobacterium animalis subsp. lactis Bl-04 Mn2+/Zn2+ ABC transporter permease YP_002968413.1 1134562 D 580050 CDS YP_002968414.1 241191020 8008945 complement(1135518..1136021) 1 NC_012814.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1136021 ispF 8008945 ispF Bifidobacterium animalis subsp. lactis Bl-04 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002968414.1 1135518 R 580050 CDS YP_002968415.1 241191021 8008946 complement(1136018..1136614) 1 NC_012814.1 COG1329 Transcriptional regulators, similar to M.xanthus CarD; transcriptional regulator 1136614 8008946 Balac_0994 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968415.1 1136018 R 580050 CDS YP_002968416.1 241191022 8008947 1136791..1139004 1 NC_012814.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1139004 8008947 Balac_0995 Bifidobacterium animalis subsp. lactis Bl-04 glycogen branching enzyme YP_002968416.1 1136791 D 580050 CDS YP_002968417.1 241191023 8008948 1139032..1139751 1 NC_012814.1 COG0745 Response regulators consisting of aCheY-like receiver domain and a winged-helix DNA-binding domain; putative response regulator 1139751 8008948 Balac_0996 Bifidobacterium animalis subsp. lactis Bl-04 putative response regulator YP_002968417.1 1139032 D 580050 CDS YP_002968418.1 241191024 8008949 1139757..1140857 1 NC_012814.1 COG0642 Signal transduction histidine kinase; sensor protein 1140857 8008949 Balac_0997 Bifidobacterium animalis subsp. lactis Bl-04 sensor protein YP_002968418.1 1139757 D 580050 CDS YP_002968419.1 241191025 8008950 complement(1140920..1141504) 1 NC_012814.1 COG1040 Predicted amidophosphoribosyltransferases; hypothetical protein 1141504 8008950 Balac_0998 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968419.1 1140920 R 580050 CDS YP_002968420.1 241191026 8008951 complement(1141711..1142517) 1 NC_012814.1 COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 1142517 8008951 Balac_0999 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968420.1 1141711 R 580050 CDS YP_002968421.1 241191027 8008952 1142718..1143038 1 NC_012814.1 hypothetical protein 1143038 8008952 Balac_1000 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968421.1 1142718 D 580050 CDS YP_002968422.1 241191028 8008953 complement(1143045..1144589) 1 NC_012814.1 hypothetical protein 1144589 8008953 Balac_1001 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968422.1 1143045 R 580050 CDS YP_002968423.1 241191029 8008954 complement(1144586..1147681) 1 NC_012814.1 COG1216 Predicted glycosyltransferases; hypothetical protein 1147681 8008954 Balac_1002 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968423.1 1144586 R 580050 CDS YP_002968424.1 241191030 8008955 1147874..1149331 1 NC_012814.1 COG1316 Transcriptional regulator; transcriptional regulator 1149331 8008955 Balac_1003 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968424.1 1147874 D 580050 CDS YP_002968425.1 241191031 8008956 1149876..1150811 1 NC_012814.1 COG1316 Transcriptional regulator; transcriptional regulator 1150811 8008956 Balac_1004 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968425.1 1149876 D 580050 CDS YP_002968426.1 241191032 8008957 1150957..1152606 1 NC_012814.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA segregation ATPase 1152606 8008957 Balac_1005 Bifidobacterium animalis subsp. lactis Bl-04 DNA segregation ATPase YP_002968426.1 1150957 D 580050 CDS YP_002968427.1 241191033 8008958 1152699..1152977 1 NC_012814.1 hypothetical protein 1152977 8008958 Balac_1006 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968427.1 1152699 D 580050 CDS YP_002968428.1 241191034 8008959 complement(1153062..1154540) 1 NC_012814.1 COG3920 Signal transduction histidine kinase; histidine kinase-like protein 1154540 8008959 Balac_1007 Bifidobacterium animalis subsp. lactis Bl-04 histidine kinase-like protein YP_002968428.1 1153062 R 580050 CDS YP_002968429.1 241191035 8008960 1154674..1155558 1 NC_012814.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 1155558 8008960 Balac_1008 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968429.1 1154674 D 580050 CDS YP_002968430.1 241191036 8008961 complement(1155639..1156121) 1 NC_012814.1 COG0782 Transcription elongation factor; transcription elongation factor GreA 1156121 8008961 Balac_1009 Bifidobacterium animalis subsp. lactis Bl-04 transcription elongation factor GreA YP_002968430.1 1155639 R 580050 CDS YP_002968431.1 241191037 8008962 complement(1156207..1156614) 1 NC_012814.1 COG0545 FKBP-type peptidyl-prolyl cis-transisomerases 1; peptidyl-prolyl cis-trans isomerase 1156614 8008962 Balac_1010 Bifidobacterium animalis subsp. lactis Bl-04 peptidyl-prolyl cis-trans isomerase YP_002968431.1 1156207 R 580050 CDS YP_002968432.1 241191038 8008963 complement(1156702..1158192) 1 NC_012814.1 COG1760 L-serine deaminase; L-serine dehydratase 1158192 8008963 Balac_1011 Bifidobacterium animalis subsp. lactis Bl-04 L-serine dehydratase YP_002968432.1 1156702 R 580050 CDS YP_002968433.1 241191039 8008964 complement(1158233..1158757) 1 NC_012814.1 Cd efflux system component 1158757 8008964 Balac_1012 Bifidobacterium animalis subsp. lactis Bl-04 Cd efflux system component YP_002968433.1 1158233 R 580050 CDS YP_002968434.1 241191040 8009597 complement(1159158..1160180) 1 NC_012814.1 COG0248 Exopolyphosphatase; exopolyphosphatase 1160180 8009597 Balac_1014 Bifidobacterium animalis subsp. lactis Bl-04 exopolyphosphatase YP_002968434.1 1159158 R 580050 CDS YP_002968435.1 241191041 8008966 complement(1160220..1160828) 1 NC_012814.1 COG1507 Uncharacterized conserved protein; hypothetical protein 1160828 8008966 Balac_1015 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968435.1 1160220 R 580050 CDS YP_002968436.1 241191042 8008967 complement(1160900..1161472) 1 NC_012814.1 COG2919 Septum formation initiator; hypothetical protein 1161472 8008967 Balac_1016 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968436.1 1160900 R 580050 CDS YP_002968437.1 241191043 8008968 complement(1161570..1162862) 1 NC_012814.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1162862 eno 8008968 eno Bifidobacterium animalis subsp. lactis Bl-04 phosphopyruvate hydratase YP_002968437.1 1161570 R 580050 CDS YP_002968438.1 241191044 8008969 1163140..1164048 1 NC_012814.1 COG0600 ABC-type nitrate/sulfonate/bicarbonatetransport system, permease component; binding-protein-dependent transport systems, inner membrane component 1164048 8008969 Balac_1018 Bifidobacterium animalis subsp. lactis Bl-04 binding-protein-dependent transport systems, inner membrane component YP_002968438.1 1163140 D 580050 CDS YP_002968439.1 241191045 8008970 1164141..1165106 1 NC_012814.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; extracellular solute-binding protein 1165106 8008970 Balac_1019 Bifidobacterium animalis subsp. lactis Bl-04 extracellular solute-binding protein YP_002968439.1 1164141 D 580050 CDS YP_002968440.1 241191046 8008971 1165279..1165977 1 NC_012814.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporter 1165977 8008971 Balac_1020 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002968440.1 1165279 D 580050 CDS YP_002968441.1 241191047 8008972 complement(1166149..1169733) 1 NC_012814.1 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 1169733 8008972 Balac_1021 Bifidobacterium animalis subsp. lactis Bl-04 transcription-repair coupling factor YP_002968441.1 1166149 R 580050 CDS YP_002968442.1 241191048 8008973 complement(1169723..1170322) 1 NC_012814.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1170322 8008973 Balac_1022 Bifidobacterium animalis subsp. lactis Bl-04 peptidyl-tRNA hydrolase YP_002968442.1 1169723 R 580050 CDS YP_002968443.1 241191049 8008974 complement(1170366..1171013) 1 NC_012814.1 COG1247 Sortase and related acyltransferases; N-acetyl transferase 1171013 8008974 Balac_1023 Bifidobacterium animalis subsp. lactis Bl-04 N-acetyl transferase YP_002968443.1 1170366 R 580050 CDS YP_002968444.1 241191050 8008975 complement(1171029..1174196) 1 NC_012814.1 COG1615 Uncharacterized conserved protein; hypothetical protein 1174196 8008975 Balac_1024 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968444.1 1171029 R 580050 CDS YP_002968445.1 241191051 8008976 1174347..1175786 1 NC_012814.1 COG1472 Beta-glucosidase-related glycosidases; B-hexosaminidase 1175786 8008976 Balac_1025 Bifidobacterium animalis subsp. lactis Bl-04 B-hexosaminidase YP_002968445.1 1174347 D 580050 CDS YP_002968446.1 241191052 8008977 complement(1175846..1176040) 1 NC_012814.1 COG2879 Uncharacterized small protein; hypothetical protein 1176040 8008977 Balac_1026 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968446.1 1175846 R 580050 CDS YP_002968447.1 241191053 8008978 complement(1176090..1178507) 1 NC_012814.1 COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein A 1178507 8008978 Balac_1027 Bifidobacterium animalis subsp. lactis Bl-04 carbon starvation protein A YP_002968447.1 1176090 R 580050 CDS YP_002968448.1 241191054 8008979 complement(1178538..1178717) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 1178717 8008979 Balac_1028 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002968448.1 1178538 R 580050 CDS YP_002968449.1 241191055 8008980 complement(1178705..1179184) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 1179184 8008980 Balac_1029 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968449.1 1178705 R 580050 CDS YP_002968450.1 241191056 8008981 complement(1179418..1179963) 1 NC_012814.1 COG3910 Predicted ATPase; SMC domain-containing protein 1179963 8008981 Balac_1030 Bifidobacterium animalis subsp. lactis Bl-04 SMC domain-containing protein YP_002968450.1 1179418 R 580050 CDS YP_002968451.1 241191057 8008982 complement(1180006..1180197) 1 NC_012814.1 hypothetical protein 1180197 8008982 Balac_1031 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968451.1 1180006 R 580050 CDS YP_002968452.1 241191058 8008983 complement(1180287..1180799) 1 NC_012814.1 COG1846 Transcriptional regulators; transcriptional regulator 1180799 8008983 Balac_1032 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968452.1 1180287 R 580050 CDS YP_002968453.1 241191059 8008984 complement(1180842..1181306) 1 NC_012814.1 Nucleoside 2-deoxyribosyltransferase 1181306 8008984 Balac_1033 Bifidobacterium animalis subsp. lactis Bl-04 Nucleoside 2-deoxyribosyltransferase YP_002968453.1 1180842 R 580050 CDS YP_002968454.1 241191060 8008985 1181483..1182952 1 NC_012814.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1182952 aspA 8008985 aspA Bifidobacterium animalis subsp. lactis Bl-04 aspartate ammonia-lyase YP_002968454.1 1181483 D 580050 CDS YP_002968455.1 241191061 8008986 1183171..1183377 1 NC_012814.1 COG1918 Fe2+ transport system protein A; hypothetical protein 1183377 8008986 Balac_1035 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968455.1 1183171 D 580050 CDS YP_002968456.1 241191062 8008987 1183426..1185477 1 NC_012814.1 COG0370 Fe2+ transport system protein B; ferrous iron transport protein B 1185477 8008987 Balac_1036 Bifidobacterium animalis subsp. lactis Bl-04 ferrous iron transport protein B YP_002968456.1 1183426 D 580050 CDS YP_002968457.1 241191063 8008988 1185573..1185842 1 NC_012814.1 hypothetical protein 1185842 8008988 Balac_1037 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968457.1 1185573 D 580050 CDS YP_002968458.1 241191064 8008989 1185981..1187540 1 NC_012814.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1187540 8008989 Balac_1038 Bifidobacterium animalis subsp. lactis Bl-04 glucose-6-phosphate 1-dehydrogenase YP_002968458.1 1185981 D 580050 CDS YP_002968459.1 241191065 8008990 1187537..1188487 1 NC_012814.1 COG3429 Glucose-6-P dehydrogenase subunit; hypothetical protein 1188487 8008990 Balac_1039 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968459.1 1187537 D 580050 CDS YP_002968460.1 241191066 8008991 1188567..1189358 1 NC_012814.1 COG03636-phosphogluconolactonase/Glucosamine-6- phosphateisomerase/deaminase; 6-phosphogluconolactonase 1189358 8008991 Balac_1040 Bifidobacterium animalis subsp. lactis Bl-04 6-phosphogluconolactonase YP_002968460.1 1188567 D 580050 CDS YP_002968461.1 241191067 8008992 complement(1189437..1190894) 1 NC_012814.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1190894 8008992 Balac_1041 Bifidobacterium animalis subsp. lactis Bl-04 6-phosphogluconate dehydrogenase YP_002968461.1 1189437 R 580050 CDS YP_002968462.1 241191068 8008993 complement(1190953..1191660) 1 NC_012814.1 COG3340 Peptidase E; hypothetical protein 1191660 8008993 Balac_1042 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968462.1 1190953 R 580050 CDS YP_002968463.1 241191069 8008994 1191811..1193175 1 NC_012814.1 COG1114 Branched-chain amino acid permeases; Branched-chain amino acid permease 1193175 8008994 Balac_1043 Bifidobacterium animalis subsp. lactis Bl-04 Branched-chain amino acid permease YP_002968463.1 1191811 D 580050 CDS YP_002968464.1 241191070 8008995 complement(1193192..1194184) 1 NC_012814.1 COG0225 Peptide methionine sulfoxide reductase; Peptide methionine sulfoxide reductase-like protein 1194184 8008995 Balac_1044 Bifidobacterium animalis subsp. lactis Bl-04 Peptide methionine sulfoxide reductase-like protein YP_002968464.1 1193192 R 580050 CDS YP_002968465.1 241191071 8008996 complement(1194192..1196912) 1 NC_012814.1 COG4633 Uncharacterized protein conserved in bacteria; ActP copper transport ATPase 1196912 8008996 Balac_1045 Bifidobacterium animalis subsp. lactis Bl-04 ActP copper transport ATPase YP_002968465.1 1194192 R 580050 CDS YP_002968466.1 241191072 8008997 1196968..1198008 1 NC_012814.1 COG0300 Short-chain dehydrogenases of various substrate specificities; short-chain dehydrogenase/reductase SDR 1198008 8008997 Balac_1046 Bifidobacterium animalis subsp. lactis Bl-04 short-chain dehydrogenase/reductase SDR YP_002968466.1 1196968 D 580050 CDS YP_002968467.1 241191073 8008998 complement(1198261..1200198) 1 NC_012814.1 COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase 1200198 8008998 Balac_1047 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent RNA helicase YP_002968467.1 1198261 R 580050 CDS YP_002968468.1 241191074 8008999 1200422..1201540 1 NC_012814.1 COG2855 Predicted membrane protein; hypothetical protein 1201540 8008999 Balac_1048 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968468.1 1200422 D 580050 CDS YP_002968469.1 241191075 8009000 1201769..1203100 1 NC_012814.1 COG2233 Xanthine/uracil permeases; purine or uracil permease 1203100 8009000 Balac_1049 Bifidobacterium animalis subsp. lactis Bl-04 purine or uracil permease YP_002968469.1 1201769 D 580050 CDS YP_002968470.1 241191076 8009001 1203239..1204312 1 NC_012814.1 COG0657 Esterase/lipase; lipase 1204312 8009001 Balac_1050 Bifidobacterium animalis subsp. lactis Bl-04 lipase YP_002968470.1 1203239 D 580050 CDS YP_002968471.1 241191077 8009002 1204397..1204777 1 NC_012814.1 hypothetical protein 1204777 8009002 Balac_1051 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968471.1 1204397 D 580050 CDS YP_002968472.1 241191078 8009003 1204943..1205293 1 NC_012814.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 1205293 8009003 Balac_1052 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968472.1 1204943 D 580050 CDS YP_002968473.1 241191079 8009004 complement(1205382..1206476) 1 NC_012814.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1206476 8009004 Balac_1053 Bifidobacterium animalis subsp. lactis Bl-04 GTP-dependent nucleic acid-binding protein EngD YP_002968473.1 1205382 R 580050 CDS YP_002968474.1 241191080 8009005 complement(1206609..1207403) 1 NC_012814.1 COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 1207403 8009005 Balac_1054 Bifidobacterium animalis subsp. lactis Bl-04 pyrroline-5-carboxylate reductase YP_002968474.1 1206609 R 580050 CDS YP_002968475.1 241191081 8009006 complement(1207466..1208803) 1 NC_012814.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); proline iminopeptidase 1208803 8009006 Balac_1055 Bifidobacterium animalis subsp. lactis Bl-04 proline iminopeptidase YP_002968475.1 1207466 R 580050 CDS YP_002968476.1 241191082 8009007 1208926..1211481 1 NC_012814.1 COG4585 Signal transduction histidine kinase; histidine kinase sensor of two-component system 1211481 8009007 Balac_1056 Bifidobacterium animalis subsp. lactis Bl-04 histidine kinase sensor of two-component system YP_002968476.1 1208926 D 580050 CDS YP_002968477.1 241191083 8009008 1211601..1212281 1 NC_012814.1 COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; putative response regulator 1212281 8009008 Balac_1057 Bifidobacterium animalis subsp. lactis Bl-04 putative response regulator YP_002968477.1 1211601 D 580050 CDS YP_002968478.1 241191084 8009009 complement(1212397..1215003) 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; SalY-type antimicrobial peptide transport system permease 1215003 8009009 Balac_1058 Bifidobacterium animalis subsp. lactis Bl-04 SalY-type antimicrobial peptide transport system permease YP_002968478.1 1212397 R 580050 CDS YP_002968479.1 241191085 8009010 complement(1215047..1215985) 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 1215985 8009010 Balac_1059 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968479.1 1215047 R 580050 CDS YP_002968480.1 241191086 8009011 complement(1216147..1216950) 1 NC_012814.1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt transport protein 1216950 8009011 Balac_1060 Bifidobacterium animalis subsp. lactis Bl-04 cobalt transport protein YP_002968480.1 1216147 R 580050 CDS YP_002968481.1 241191087 8009012 complement(1216950..1218485) 1 NC_012814.1 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 1218485 8009012 Balac_1061 Bifidobacterium animalis subsp. lactis Bl-04 cobalt ABC transporter ATPase YP_002968481.1 1216950 R 580050 CDS YP_002968482.1 241191088 8009013 complement(1218566..1218727) 1 NC_012814.1 hypothetical protein 1218727 8009013 Balac_1062 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968482.1 1218566 R 580050 CDS YP_002968483.1 241191089 8009014 complement(1218734..1220056) 1 NC_012814.1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase 1220056 8009014 Balac_1063 Bifidobacterium animalis subsp. lactis Bl-04 O-acetylhomoserine sulfhydrylase YP_002968483.1 1218734 R 580050 CDS YP_002968484.1 241191090 8009015 1220362..1221231 1 NC_012814.1 COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxine kinase 1221231 8009015 Balac_1064 Bifidobacterium animalis subsp. lactis Bl-04 pyridoxine kinase YP_002968484.1 1220362 D 580050 CDS YP_002968485.1 241191091 8009016 1221428..1221904 1 NC_012814.1 COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein 1221904 8009016 Balac_1065 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968485.1 1221428 D 580050 CDS YP_002968486.1 241191092 8009017 1221904..1223436 1 NC_012814.1 COG0606 Predicted ATPase with chaperone activity; putative ATP-dependent serine protease 1223436 8009017 Balac_1066 Bifidobacterium animalis subsp. lactis Bl-04 putative ATP-dependent serine protease YP_002968486.1 1221904 D 580050 CDS YP_002968487.1 241191093 8009018 1223470..1224615 1 NC_012814.1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 1224615 8009018 Balac_1067 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968487.1 1223470 D 580050 CDS YP_002968488.1 241191094 8009019 1224668..1226503 1 NC_012814.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit 1226503 8009019 Balac_1068 Bifidobacterium animalis subsp. lactis Bl-04 succinate dehydrogenase flavoprotein subunit YP_002968488.1 1224668 D 580050 CDS YP_002968489.1 241191095 8009020 1226612..1227568 1 NC_012814.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Succinate dehydrogenase/fumarate reductase Fe-Sprotein subunit 1227568 8009020 Balac_1069 Bifidobacterium animalis subsp. lactis Bl-04 Succinate dehydrogenase/fumarate reductase Fe-Sprotein subunit YP_002968489.1 1226612 D 580050 CDS YP_002968490.1 241191096 8009021 1227581..1228252 1 NC_012814.1 COG4122 Predicted O-methyltransferase; methyltransferase 1228252 8009021 Balac_1070 Bifidobacterium animalis subsp. lactis Bl-04 methyltransferase YP_002968490.1 1227581 D 580050 CDS YP_002968491.1 241191097 8009022 complement(1228315..1229118) 1 NC_012814.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein 1229118 8009022 Balac_1071 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968491.1 1228315 R 580050 CDS YP_002968492.1 241191098 8009023 complement(1229197..1230597) 1 NC_012814.1 COG3004 Na+/H+ antiporter; Kef-type K+ transport systems membrane protein 1230597 8009023 Balac_1072 Bifidobacterium animalis subsp. lactis Bl-04 Kef-type K+ transport systems membrane protein YP_002968492.1 1229197 R 580050 CDS YP_002968493.1 241191099 8009024 complement(1230683..1231903) 1 NC_012814.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; class I and II aminotransferase 1231903 8009024 Balac_1073 Bifidobacterium animalis subsp. lactis Bl-04 class I and II aminotransferase YP_002968493.1 1230683 R 580050 CDS YP_002968494.1 241191100 8009599 complement(1232353..1233681) 1 NC_012814.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1233681 clpX 8009599 clpX Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent protease ATP-binding subunit ClpX YP_002968494.1 1232353 R 580050 CDS YP_002968495.1 241191101 8009026 complement(1233783..1234484) 1 NC_012814.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1234484 clpP 8009026 clpP Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent Clp protease proteolytic subunit YP_002968495.1 1233783 R 580050 CDS YP_002968496.1 241191102 8009027 complement(1234487..1235101) 1 NC_012814.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit 2 1235101 8009027 Balac_1078 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent Clp protease proteolytic subunit 2 YP_002968496.1 1234487 R 580050 CDS YP_002968497.1 241191103 8009028 complement(1235200..1236597) 1 NC_012814.1 COG0038 Chloride channel protein EriC; hypothetical protein 1236597 8009028 Balac_1079 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968497.1 1235200 R 580050 CDS YP_002968498.1 241191104 8009029 complement(1236672..1238057) 1 NC_012814.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1238057 tig 8009029 tig Bifidobacterium animalis subsp. lactis Bl-04 trigger factor YP_002968498.1 1236672 R 580050 CDS YP_002968499.1 241191105 8009030 complement(1238115..1239416) 1 NC_012814.1 COG0349 Ribonuclease D; hypothetical protein 1239416 8009030 Balac_1081 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968499.1 1238115 R 580050 CDS YP_002968500.1 241191106 8009031 complement(1239517..1240419) 1 NC_012814.1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate-lyase 1 activating enzyme 1240419 8009031 Balac_1082 Bifidobacterium animalis subsp. lactis Bl-04 pyruvate formate-lyase 1 activating enzyme YP_002968500.1 1239517 R 580050 CDS YP_002968501.1 241191107 8009032 complement(1240510..1242888) 1 NC_012814.1 COG1882 Pyruvate-formate lyase; formate acetyltransferase 1242888 8009032 Balac_1083 Bifidobacterium animalis subsp. lactis Bl-04 formate acetyltransferase YP_002968501.1 1240510 R 580050 CDS YP_002968502.1 241191108 8009033 complement(1243114..1243314) 1 NC_012814.1 hypothetical protein 1243314 8009033 Balac_1084 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968502.1 1243114 R 580050 CDS YP_002968503.1 241191109 8009034 complement(1243356..1245056) 1 NC_012814.1 COG0388 Predicted amidohydrolase; putative amidohydrolase 1245056 8009034 Balac_1085 Bifidobacterium animalis subsp. lactis Bl-04 putative amidohydrolase YP_002968503.1 1243356 R 580050 CDS YP_002968504.1 241191110 8009035 complement(1245276..1246439) 1 NC_012814.1 COG1473 Metal-dependentamidase/aminoacylase/carboxypeptidase; hypothetical protein 1246439 8009035 Balac_1086 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968504.1 1245276 R 580050 CDS YP_002968505.1 241191111 8009036 complement(1246544..1247254) 1 NC_012814.1 COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter permease 1247254 8009036 Balac_1087 Bifidobacterium animalis subsp. lactis Bl-04 metal ion ABC transporter permease YP_002968505.1 1246544 R 580050 CDS YP_002968506.1 241191112 8009037 complement(1247254..1248549) 1 NC_012814.1 COG1135 ABC-type metal ion transport system, ATPase component; ABC transporter ATP-binding protein 1248549 8009037 Balac_1088 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968506.1 1247254 R 580050 CDS YP_002968507.1 241191113 8009038 complement(1248736..1249734) 1 NC_012814.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; metal ion ABC transporter periplasmic component 1249734 8009038 Balac_1089 Bifidobacterium animalis subsp. lactis Bl-04 metal ion ABC transporter periplasmic component YP_002968507.1 1248736 R 580050 CDS YP_002968508.1 241191114 8009039 1249964..1250488 1 NC_012814.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase - cyclophilin family); peptidyl-prolyl cis-trans isomerase 1250488 8009039 Balac_1090 Bifidobacterium animalis subsp. lactis Bl-04 peptidyl-prolyl cis-trans isomerase YP_002968508.1 1249964 D 580050 CDS YP_002968509.1 241191115 8009040 complement(1250583..1252916) 1 NC_012814.1 COG0317 Guanosine polyphosphatepyrophosphohydrolases/synthetases; GTP pyrophosphokinase 1252916 8009040 Balac_1091 Bifidobacterium animalis subsp. lactis Bl-04 GTP pyrophosphokinase YP_002968509.1 1250583 R 580050 CDS YP_002968510.1 241191116 8009041 complement(1253023..1253490) 1 NC_012814.1 COG0756 dUTPase; dUTPase 1253490 8009041 Balac_1092 Bifidobacterium animalis subsp. lactis Bl-04 dUTPase YP_002968510.1 1253023 R 580050 CDS YP_002968511.1 241191117 8009042 complement(1253490..1253783) 1 NC_012814.1 hypothetical protein 1253783 8009042 Balac_1093 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968511.1 1253490 R 580050 CDS YP_002968512.1 241191118 8009043 1253910..1255244 1 NC_012814.1 hypothetical protein 1255244 8009043 Balac_1094 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968512.1 1253910 D 580050 CDS YP_002968513.1 241191119 8009044 complement(1255256..1256533) 1 NC_012814.1 COG1524 Uncharacterized proteins of the AP superfamily; hypothetical protein 1256533 8009044 Balac_1095 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968513.1 1255256 R 580050 CDS YP_002968514.1 241191120 8009045 1256656..1259331 1 NC_012814.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1259331 8009045 Balac_1096 Bifidobacterium animalis subsp. lactis Bl-04 DNA topoisomerase IV subunit A YP_002968514.1 1256656 D 580050 CDS YP_002968515.1 241191121 8009046 complement(1259414..1260373) 1 NC_012814.1 COG4975 Putative glucose uptake permease; putative glucose uptake permease 1260373 glcU 8009046 glcU Bifidobacterium animalis subsp. lactis Bl-04 putative glucose uptake permease YP_002968515.1 1259414 R 580050 CDS YP_002968516.1 241191122 8009047 complement(1260505..1265166) 1 NC_012814.1 COG1201 Lhr-like helicases; ATP-dependent helicase II 1265166 8009047 Balac_1098 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent helicase II YP_002968516.1 1260505 R 580050 CDS YP_002968517.1 241191123 8009048 complement(1265194..1265823) 1 NC_012814.1 major facilitator transporter 1265823 8009048 Balac_1099 Bifidobacterium animalis subsp. lactis Bl-04 major facilitator transporter YP_002968517.1 1265194 R 580050 CDS YP_002968518.1 241191124 8009049 complement(1266542..1267723) 1 NC_012814.1 COG0738 Fucose permease; hypothetical protein 1267723 8009049 Balac_1100 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968518.1 1266542 R 580050 CDS YP_002968519.1 241191125 8009050 1267836..1269008 1 NC_012814.1 COG0438 Glycosyltransferase; phosphatidylinositol alpha-mannosyltransferase 1269008 8009050 Balac_1101 Bifidobacterium animalis subsp. lactis Bl-04 phosphatidylinositol alpha-mannosyltransferase YP_002968519.1 1267836 D 580050 CDS YP_002968520.1 241191126 8009051 complement(1269143..1271482) 1 NC_012814.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II,topoisomerase IV, B subunit); DNA gyrase subunit B 1271482 8009051 Balac_1102 Bifidobacterium animalis subsp. lactis Bl-04 DNA gyrase subunit B YP_002968520.1 1269143 R 580050 CDS YP_002968521.1 241191127 8009052 complement(1271617..1273083) 1 NC_012814.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 1273083 8009052 Balac_1103 Bifidobacterium animalis subsp. lactis Bl-04 RNA polymerase sigma factor YP_002968521.1 1271617 R 580050 CDS YP_002968522.1 241191128 8009053 complement(1273215..1273919) 1 NC_012814.1 hypothetical protein 1273919 8009053 Balac_1104 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968522.1 1273215 R 580050 CDS YP_002968523.1 241191129 8009054 1274100..1275200 1 NC_012814.1 COG0142 Geranylgeranyl pyrophosphate synthase; bifunctional short chain isoprenyl diphosphatesynthase 1275200 8009054 Balac_1105 Bifidobacterium animalis subsp. lactis Bl-04 bifunctional short chain isoprenyl diphosphatesynthase YP_002968523.1 1274100 D 580050 CDS YP_002968524.1 241191130 8009055 1275260..1277485 1 NC_012814.1 COG0515 Serine/threonine protein kinase; serine-threonine protein kinase 1277485 8009055 Balac_1106 Bifidobacterium animalis subsp. lactis Bl-04 serine-threonine protein kinase YP_002968524.1 1275260 D 580050 CDS YP_002968525.1 241191131 8009056 complement(1277535..1278275) 1 NC_012814.1 COG0204 1-acyl-sn-glycerol-3-phosphateacyltransferase; hypothetical protein 1278275 8009056 Balac_1107 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968525.1 1277535 R 580050 CDS YP_002968526.1 241191132 8009057 1278325..1278891 1 NC_012814.1 hypothetical protein 1278891 8009057 Balac_1108 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968526.1 1278325 D 580050 CDS YP_002968527.1 241191133 8009058 complement(1278983..1280035) 1 NC_012814.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1280035 trpD 8009058 trpD Bifidobacterium animalis subsp. lactis Bl-04 anthranilate phosphoribosyltransferase YP_002968527.1 1278983 R 580050 CDS YP_002968528.1 241191134 8009059 complement(1280169..1283093) 1 NC_012814.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1283093 8009059 Balac_1110 Bifidobacterium animalis subsp. lactis Bl-04 preprotein translocase subunit SecA YP_002968528.1 1280169 R 580050 CDS YP_002968529.1 241191135 8009060 complement(1283301..1283987) 1 NC_012814.1 COG1544 Ribosome-associated protein Y (PSrp-1); hypothetical protein 1283987 8009060 Balac_1111 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968529.1 1283301 R 580050 CDS YP_002968530.1 241191136 8009061 1284460..1284591 1 NC_012814.1 hypothetical protein 1284591 8009061 Balac_1112 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968530.1 1284460 D 580050 CDS YP_002968531.1 241191137 8009062 complement(1284659..1285288) 1 NC_012814.1 COG2137 Uncharacterized protein conserved in bacteria; RecX-like protein 1285288 8009062 Balac_1113 Bifidobacterium animalis subsp. lactis Bl-04 RecX-like protein YP_002968531.1 1284659 R 580050 CDS YP_002968532.1 241191138 8009063 complement(1285398..1286546) 1 NC_012814.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1286546 recA 8009063 recA Bifidobacterium animalis subsp. lactis Bl-04 recombinase A YP_002968532.1 1285398 R 580050 CDS YP_002968533.1 241191139 8009064 complement(1286818..1287069) 1 NC_012814.1 hypothetical protein 1287069 8009064 Balac_1115 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968533.1 1286818 R 580050 CDS YP_002968534.1 241191140 8009065 complement(1287199..1287714) 1 NC_012814.1 COG1396 Predicted transcriptional regulators; DNA binding protein 1287714 8009065 Balac_1116 Bifidobacterium animalis subsp. lactis Bl-04 DNA binding protein YP_002968534.1 1287199 R 580050 CDS YP_002968535.1 241191141 8009066 complement(1287737..1288363) 1 NC_012814.1 COG1546 Uncharacterized protein (competence- andmitomycin-induced); CinA-like protein 1288363 8009066 Balac_1117 Bifidobacterium animalis subsp. lactis Bl-04 CinA-like protein YP_002968535.1 1287737 R 580050 CDS YP_002968536.1 241191142 8009067 complement(1288546..1289169) 1 NC_012814.1 COG0558 Phosphatidylglycerophosphate synthase; DP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1289169 8009067 Balac_1118 Bifidobacterium animalis subsp. lactis Bl-04 DP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002968536.1 1288546 R 580050 CDS YP_002968537.1 241191143 8009068 complement(1289315..1291930) 1 NC_012814.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase ftsK 1291930 8009068 Balac_1119 Bifidobacterium animalis subsp. lactis Bl-04 DNA translocase ftsK YP_002968537.1 1289315 R 580050 CDS YP_002968538.1 241191144 8009069 complement(1292188..1293222) 1 NC_012814.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1293222 miaA 8009069 miaA Bifidobacterium animalis subsp. lactis Bl-04 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002968538.1 1292188 R 580050 CDS YP_002968539.1 241191145 8009070 complement(1293203..1294678) 1 NC_012814.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1294678 8009070 Balac_1121 Bifidobacterium animalis subsp. lactis Bl-04 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002968539.1 1293203 R 580050 CDS YP_002968540.1 241191146 8009071 1294754..1295572 1 NC_012814.1 COG2357 Uncharacterized protein conserved in bacteria; hypothetical protein 1295572 8009071 Balac_1122 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968540.1 1294754 D 580050 CDS YP_002968541.1 241191147 8009072 complement(1295658..1296443) 1 NC_012814.1 COG0670 Integral membrane protein, interacts withFtsH; hypothetical protein 1296443 8009072 Balac_1123 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968541.1 1295658 R 580050 CDS YP_002968542.1 241191148 8009073 1296705..1297730 1 NC_012814.1 COG3804 Uncharacterized conserved protein related to dihydrodipicolinate reductase; hypothetical protein 1297730 8009073 Balac_1124 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968542.1 1296705 D 580050 CDS YP_002968543.1 241191149 8009074 complement(1299146..1300426) 1 NC_012814.1 multidrug ABC transporter permease 1300426 8009074 Balac_1125 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter permease YP_002968543.1 1299146 R 580050 CDS YP_002968544.1 241191150 8009075 complement(1300460..1301449) 1 NC_012814.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 1301449 8009075 Balac_1126 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968544.1 1300460 R 580050 CDS YP_002968545.1 241191151 8009076 1301596..1302762 1 NC_012814.1 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 1302762 8009076 Balac_1127 Bifidobacterium animalis subsp. lactis Bl-04 signal transduction histidine kinase YP_002968545.1 1301596 D 580050 CDS YP_002968546.1 241191152 8009077 1302759..1303415 1 NC_012814.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 1303415 8009077 Balac_1128 Bifidobacterium animalis subsp. lactis Bl-04 two-component system response regulator YP_002968546.1 1302759 D 580050 CDS YP_002968547.1 241191153 8009078 complement(1303397..1304212) 1 NC_012814.1 hypothetical protein 1304212 8009078 Balac_1129 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968547.1 1303397 R 580050 CDS YP_002968548.1 241191154 8009079 complement(1304241..1305374) 1 NC_012814.1 COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 1305374 8009079 Balac_1130 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS204/IS1001/IS1096/IS1165 family protein YP_002968548.1 1304241 R 580050 CDS YP_002968549.1 241191155 8009080 complement(1305581..1306894) 1 NC_012814.1 COG1479 Uncharacterized conserved protein; hypothetical protein 1306894 8009080 Balac_1131 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968549.1 1305581 R 580050 CDS YP_002968550.1 241191156 8009081 complement(1307042..1307683) 1 NC_012814.1 COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 1307683 8009081 Balac_1132 Bifidobacterium animalis subsp. lactis Bl-04 galactoside O-acetyltransferase YP_002968550.1 1307042 R 580050 CDS YP_002968551.1 241191157 8009082 1307856..1308107 1 NC_012814.1 hypothetical protein 1308107 8009082 Balac_1133 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968551.1 1307856 D 580050 CDS YP_002968552.1 241191158 8009083 complement(1308191..1310890) 1 NC_012814.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1310890 8009083 Balac_1134 Bifidobacterium animalis subsp. lactis Bl-04 aconitate hydratase YP_002968552.1 1308191 R 580050 CDS YP_002968553.1 241191159 8009084 complement(1310958..1313528) 1 NC_012814.1 COG0474 Cation transport ATPase; cation-transporting ATPase 1313528 8009084 Balac_1135 Bifidobacterium animalis subsp. lactis Bl-04 cation-transporting ATPase YP_002968553.1 1310958 R 580050 CDS YP_002968554.1 241191160 8009085 complement(1313577..1314164) 1 NC_012814.1 hypothetical protein 1314164 8009085 Balac_1136 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968554.1 1313577 R 580050 CDS YP_002968555.1 241191161 8009086 complement(1314500..1315810) 1 NC_012814.1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5--methyltransferase); RNA methyltransferase 1315810 8009086 Balac_1137 Bifidobacterium animalis subsp. lactis Bl-04 RNA methyltransferase YP_002968555.1 1314500 R 580050 CDS YP_002968556.1 241191162 8009087 complement(1315924..1316694) 1 NC_012814.1 hypothetical protein 1316694 8009087 Balac_1138 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968556.1 1315924 R 580050 CDS YP_002968557.1 241191163 8009088 complement(1316763..1317620) 1 NC_012814.1 hypothetical protein 1317620 8009088 Balac_1139 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968557.1 1316763 R 580050 CDS YP_002968558.1 241191164 8009089 complement(1317754..1318614) 1 NC_012814.1 COG0708 Exonuclease III; exodeoxyribonuclease 1318614 8009089 Balac_1140 Bifidobacterium animalis subsp. lactis Bl-04 exodeoxyribonuclease YP_002968558.1 1317754 R 580050 CDS YP_002968559.1 241191165 8009090 1318788..1319462 1 NC_012814.1 hypothetical protein 1319462 8009090 Balac_1141 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968559.1 1318788 D 580050 CDS YP_002968560.1 241191166 8009091 complement(1319722..1321785) 1 NC_012814.1 COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; dipeptide transport ATP-binding protein 1321785 8009091 Balac_1142 Bifidobacterium animalis subsp. lactis Bl-04 dipeptide transport ATP-binding protein YP_002968560.1 1319722 R 580050 CDS YP_002968561.1 241191167 8009092 complement(1321782..1322738) 1 NC_012814.1 COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 1322738 8009092 Balac_1143 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter permease YP_002968561.1 1321782 R 580050 CDS YP_002968562.1 241191168 8009093 complement(1322752..1323678) 1 NC_012814.1 COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease 1323678 8009093 Balac_1144 Bifidobacterium animalis subsp. lactis Bl-04 dipeptide/oligopeptide/nickel ABC transporter permease YP_002968562.1 1322752 R 580050 CDS YP_002968563.1 241191169 8009094 complement(1323978..1325618) 1 NC_012814.1 COG0747 ABC-type dipeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic component 1325618 8009094 Balac_1145 Bifidobacterium animalis subsp. lactis Bl-04 oligopeptide ABC transporter periplasmic component YP_002968563.1 1323978 R 580050 CDS YP_002968564.1 241191170 8009095 complement(1325895..1326830) 1 NC_012814.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1326830 xerC 8009095 xerC Bifidobacterium animalis subsp. lactis Bl-04 site-specific tyrosine recombinase XerC YP_002968564.1 1325895 R 580050 CDS YP_002968565.1 241191171 8009096 1327069..1327875 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 1327875 8009096 Balac_1147 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter ATP-binding protein YP_002968565.1 1327069 D 580050 CDS YP_002968566.1 241191172 8009097 1327883..1330717 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein 1330717 8009097 Balac_1148 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter integral membrane protein YP_002968566.1 1327883 D 580050 CDS YP_002968567.1 241191173 8009098 1330862..1331113 1 NC_012814.1 hypothetical protein 1331113 8009098 Balac_1149 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968567.1 1330862 D 580050 CDS YP_002968568.1 241191174 8009099 complement(1331129..1332223) 1 NC_012814.1 COG0287 Prephenate dehydrogenase; prephenate dehydrogenase 1332223 8009099 Balac_1150 Bifidobacterium animalis subsp. lactis Bl-04 prephenate dehydrogenase YP_002968568.1 1331129 R 580050 CDS YP_002968569.1 241191175 8009100 complement(1332232..1333347) 1 NC_012814.1 COG0077 Prephenate dehydratase; chorismate mutase 1333347 8009100 Balac_1151 Bifidobacterium animalis subsp. lactis Bl-04 chorismate mutase YP_002968569.1 1332232 R 580050 CDS YP_002968570.1 241191176 8009101 complement(1333370..1333879) 1 NC_012814.1 hypothetical protein 1333879 8009101 Balac_1152 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968570.1 1333370 R 580050 CDS YP_002968571.1 241191177 8009102 complement(1333989..1335920) 1 NC_012814.1 COG1217 Predicted membrane GTPase involved instress response; GTP-binding elongation factor TypA/BipA 1335920 8009102 Balac_1153 Bifidobacterium animalis subsp. lactis Bl-04 GTP-binding elongation factor TypA/BipA YP_002968571.1 1333989 R 580050 CDS YP_002968572.1 241191178 8009103 complement(1336274..1337683) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; sugar transporter 1337683 8009103 Balac_1154 Bifidobacterium animalis subsp. lactis Bl-04 sugar transporter YP_002968572.1 1336274 R 580050 CDS YP_002968573.1 241191179 8009104 complement(1337745..1338554) 1 NC_012814.1 COG1051 ADP-ribose pyrophosphatase; hypothetical protein 1338554 8009104 Balac_1155 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968573.1 1337745 R 580050 CDS YP_002968574.1 241191180 8009105 complement(1338755..1339603) 1 NC_012814.1 COG1192 ATPases involved in chromosome partitioning; hypothetical protein 1339603 8009105 Balac_1156 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968574.1 1338755 R 580050 CDS YP_002968575.1 241191181 8009106 complement(1339707..1340630) 1 NC_012814.1 COG4974 Site-specific recombinase XerD; Integrase 1340630 8009106 Balac_1157 Bifidobacterium animalis subsp. lactis Bl-04 Integrase YP_002968575.1 1339707 R 580050 CDS YP_002968576.1 241191182 8009107 complement(1341022..1341405) 1 NC_012814.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1341405 rplT 8009107 rplT Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L20 YP_002968576.1 1341022 R 580050 CDS YP_002968577.1 241191183 8009108 complement(1341455..1341646) 1 NC_012814.1 50S ribosomal protein L35 1341646 rpmI 8009108 rpmI Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L35 YP_002968577.1 1341455 R 580050 CDS YP_002968578.1 241191184 8009109 complement(1341690..1342364) 1 NC_012814.1 COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 1342364 8009109 Balac_1160 Bifidobacterium animalis subsp. lactis Bl-04 translation initiation factor IF-3 YP_002968578.1 1341690 R 580050 CDS YP_002968579.1 241191185 8009110 1342816..1343622 1 NC_012814.1 COG1564 Thiamine pyrophosphokinase; hypothetical protein 1343622 8009110 Balac_1161 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968579.1 1342816 D 580050 CDS YP_002968580.1 241191186 8009111 1343853..1344911 1 NC_012814.1 COG0057 Glyceraldehyde-3-phosphatedehydrogenase/erythrose-4- phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 1344911 8009111 Balac_1162 Bifidobacterium animalis subsp. lactis Bl-04 glyceraldehyde-3-phosphate dehydrogenase YP_002968580.1 1343853 D 580050 CDS YP_002968581.1 241191187 8009112 1345334..1345843 1 NC_012814.1 COG2606 Uncharacterized conserved protein; hypothetical protein 1345843 8009112 Balac_1163 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968581.1 1345334 D 580050 CDS YP_002968582.1 241191188 8009113 complement(1346071..1347048) 1 NC_012814.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1347048 ispH 8009113 ispH Bifidobacterium animalis subsp. lactis Bl-04 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002968582.1 1346071 R 580050 CDS YP_002968583.1 241191189 8009114 1347138..1348130 1 NC_012814.1 COG2017 Galactose mutarotase and related enzymes; hypothetical protein 1348130 8009114 Balac_1165 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968583.1 1347138 D 580050 CDS YP_002968584.1 241191190 8009115 complement(1348479..1348790) 1 NC_012814.1 hypothetical protein 1348790 8009115 Balac_1166 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968584.1 1348479 R 580050 CDS YP_002968585.1 241191191 8009116 complement(1348787..1349530) 1 NC_012814.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 1349530 8009116 Balac_1167 Bifidobacterium animalis subsp. lactis Bl-04 RNA polymerase sigma factor RpoE YP_002968585.1 1348787 R 580050 CDS YP_002968586.1 241191192 8009117 1349669..1351219 1 NC_012814.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1351219 murE 8009117 murE Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002968586.1 1349669 D 580050 CDS YP_002968587.1 241191193 8009118 1351270..1352319 1 NC_012814.1 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 1352319 8009118 Balac_1169 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968587.1 1351270 D 580050 CDS YP_002968588.1 241191194 8009119 complement(1352555..1354120) 1 NC_012814.1 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 1354120 8009119 Balac_1170 Bifidobacterium animalis subsp. lactis Bl-04 folylpolyglutamate synthase YP_002968588.1 1352555 R 580050 CDS YP_002968589.1 241191195 8009120 1354258..1354881 1 NC_012814.1 COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; response regulator 1354881 8009120 Balac_1171 Bifidobacterium animalis subsp. lactis Bl-04 response regulator YP_002968589.1 1354258 D 580050 CDS YP_002968590.1 241191196 8009121 1354883..1356037 1 NC_012814.1 COG4585 Signal transduction histidine kinase; hypothetical protein 1356037 8009121 Balac_1172 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968590.1 1354883 D 580050 CDS YP_002968591.1 241191197 8009122 complement(1356050..1356841) 1 NC_012814.1 hypothetical protein 1356841 8009122 Balac_1173 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968591.1 1356050 R 580050 CDS YP_002968592.1 241191198 8009123 1357070..1358641 1 NC_012814.1 COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 1358641 8009123 Balac_1174 Bifidobacterium animalis subsp. lactis Bl-04 Xaa-Pro aminopeptidase YP_002968592.1 1357070 D 580050 CDS YP_002968593.1 241191199 8009124 1358665..1359192 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein 1359192 8009124 Balac_1175 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968593.1 1358665 D 580050 CDS YP_002968594.1 241191200 8009125 1359445..1360650 1 NC_012814.1 COG1940 Transcriptional regulator/sugar kinase; ROK family transcriptional regulator 1360650 8009125 Balac_1176 Bifidobacterium animalis subsp. lactis Bl-04 ROK family transcriptional regulator YP_002968594.1 1359445 D 580050 CDS YP_002968595.1 241191201 8009126 1360713..1361609 1 NC_012814.1 COG0524 Sugar kinases, ribokinase family; 2-dehydro-3-deoxygluconokinase 1361609 8009126 Balac_1177 Bifidobacterium animalis subsp. lactis Bl-04 2-dehydro-3-deoxygluconokinase YP_002968595.1 1360713 D 580050 CDS YP_002968596.1 241191202 8009127 1361708..1362175 1 NC_012814.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1362175 8009127 Balac_1178 Bifidobacterium animalis subsp. lactis Bl-04 D-tyrosyl-tRNA(Tyr) deacylase YP_002968596.1 1361708 D 580050 CDS YP_002968597.1 241191203 8009128 complement(1362448..1363548) 1 NC_012814.1 COG0582 Integrase; phage-related integrase 1363548 8009128 Balac_1179 Bifidobacterium animalis subsp. lactis Bl-04 phage-related integrase YP_002968597.1 1362448 R 580050 CDS YP_002968598.1 241191204 8009129 complement(1363761..1364378) 1 NC_012814.1 hypothetical protein 1364378 8009129 Balac_1180 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968598.1 1363761 R 580050 CDS YP_002968599.1 241191205 8009130 1364530..1364736 1 NC_012814.1 COG3311 Predicted transcriptional regulator; hypothetical protein 1364736 8009130 Balac_1181 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968599.1 1364530 D 580050 CDS YP_002968600.1 241191206 8009131 1364751..1364963 1 NC_012814.1 hypothetical protein 1364963 8009131 Balac_1182 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968600.1 1364751 D 580050 CDS YP_002968601.1 241191207 8009132 1364976..1365212 1 NC_012814.1 hypothetical protein 1365212 8009132 Balac_1183 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968601.1 1364976 D 580050 CDS YP_002968602.1 241191208 8009133 1365217..1365408 1 NC_012814.1 hypothetical protein 1365408 8009133 Balac_1184 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968602.1 1365217 D 580050 CDS YP_002968603.1 241191209 8009134 1365396..1365587 1 NC_012814.1 hypothetical protein 1365587 8009134 Balac_1185 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968603.1 1365396 D 580050 CDS YP_002968604.1 241191210 8009135 1365578..1366780 1 NC_012814.1 COG0305 Replicative DNA helicase; hypothetical protein 1366780 8009135 Balac_1186 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968604.1 1365578 D 580050 CDS YP_002968605.1 241191211 8009136 1367018..1367290 1 NC_012814.1 hypothetical protein 1367290 8009136 Balac_1187 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968605.1 1367018 D 580050 CDS YP_002968606.1 241191212 8009137 1367287..1367475 1 NC_012814.1 hypothetical protein 1367475 8009137 Balac_1188 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968606.1 1367287 D 580050 CDS YP_002968607.1 241191213 8009138 1367498..1367734 1 NC_012814.1 hypothetical protein 1367734 8009138 Balac_1189 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968607.1 1367498 D 580050 CDS YP_002968608.1 241191214 8009139 1367731..1368048 1 NC_012814.1 hypothetical protein 1368048 8009139 Balac_1190 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968608.1 1367731 D 580050 CDS YP_002968609.1 241191215 8009140 1368464..1370227 1 NC_012814.1 COG3740 Phage head maturation protease; HK97 family phage prohead protease 1370227 8009140 Balac_1191 Bifidobacterium animalis subsp. lactis Bl-04 HK97 family phage prohead protease YP_002968609.1 1368464 D 580050 CDS YP_002968610.1 241191216 8009141 1370239..1370460 1 NC_012814.1 hypothetical protein 1370460 8009141 Balac_1192 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968610.1 1370239 D 580050 CDS YP_002968611.1 241191217 8009142 complement(1371202..1372932) 1 NC_012814.1 COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; peptide ABC transporter ATPase 1372932 8009142 Balac_1193 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter ATPase YP_002968611.1 1371202 R 580050 CDS YP_002968612.1 241191218 8009143 complement(1372922..1374109) 1 NC_012814.1 COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 1374109 8009143 Balac_1194 Bifidobacterium animalis subsp. lactis Bl-04 peptide ABC transporter permease YP_002968612.1 1372922 R 580050 CDS YP_002968613.1 241191219 8009144 complement(1374141..1375232) 1 NC_012814.1 COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease 1375232 8009144 Balac_1195 Bifidobacterium animalis subsp. lactis Bl-04 dipeptide/oligopeptide/nickel ABC transporter permease YP_002968613.1 1374141 R 580050 CDS YP_002968614.1 241191220 8009145 complement(1377194..1378447) 1 NC_012814.1 COG1589 Cell division septal protein; cell division protein 1378447 8009145 Balac_1196 Bifidobacterium animalis subsp. lactis Bl-04 cell division protein YP_002968614.1 1377194 R 580050 CDS YP_002968615.1 241191221 8009146 complement(1378608..1380149) 1 NC_012814.1 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate--L-alanine ligase 1380149 8009146 Balac_1197 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylmuramate--L-alanine ligase YP_002968615.1 1378608 R 580050 CDS YP_002968616.1 241191222 8009147 complement(1380190..1381374) 1 NC_012814.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 1381374 murG 8009147 murG Bifidobacterium animalis subsp. lactis Bl-04 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002968616.1 1380190 R 580050 CDS YP_002968617.1 241191223 8009148 complement(1381429..1382811) 1 NC_012814.1 COG0772 Bacterial cell division membrane protein; FtsW-like protein 1382811 8009148 Balac_1199 Bifidobacterium animalis subsp. lactis Bl-04 FtsW-like protein YP_002968617.1 1381429 R 580050 CDS YP_002968618.1 241191224 8009149 complement(1382792..1384237) 1 NC_012814.1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamateligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase 1384237 8009149 Balac_1200 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_002968618.1 1382792 R 580050 CDS YP_002968619.1 241191225 8009150 complement(1384339..1385445) 1 NC_012814.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1385445 mraY 8009150 mraY Bifidobacterium animalis subsp. lactis Bl-04 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002968619.1 1384339 R 580050 CDS YP_002968620.1 241191226 8009151 complement(1385497..1386987) 1 NC_012814.1 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1386987 8009151 Balac_1202 Bifidobacterium animalis subsp. lactis Bl-04 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002968620.1 1385497 R 580050 CDS YP_002968621.1 241191227 8009152 complement(1387025..1387906) 1 NC_012814.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; hypothetical protein 1387906 8009152 Balac_1203 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968621.1 1387025 R 580050 CDS YP_002968622.1 241191228 8009153 complement(1387921..1389717) 1 NC_012814.1 COG0768 Cell division proteinFtsI/ penicillin-binding protein 2; peptidoglycan synthetase; penicillin-binding protein 3 1389717 8009153 Balac_1204 Bifidobacterium animalis subsp. lactis Bl-04 peptidoglycan synthetase; penicillin-binding protein 3 YP_002968622.1 1387921 R 580050 CDS YP_002968623.1 241191229 8009154 complement(1389714..1390244) 1 NC_012814.1 hypothetical protein 1390244 8009154 Balac_1205 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968623.1 1389714 R 580050 CDS YP_002968624.1 241191230 8009155 complement(1390246..1391307) 1 NC_012814.1 COG0275 Predicted S-adenosylmethionine-dependentmethyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW 1391307 mraW 8009155 mraW Bifidobacterium animalis subsp. lactis Bl-04 S-adenosyl-methyltransferase MraW YP_002968624.1 1390246 R 580050 CDS YP_002968625.1 241191231 8009156 complement(1391307..1391792) 1 NC_012814.1 COG2001 Uncharacterized protein conserved in bacteria; protein mraZ 1391792 8009156 Balac_1207 Bifidobacterium animalis subsp. lactis Bl-04 protein mraZ YP_002968625.1 1391307 R 580050 CDS YP_002968626.1 241191232 8009157 1392146..1394407 1 NC_012814.1 COG3973 Superfamily I DNA and RNA helicases; hypothetical protein 1394407 8009157 Balac_1208 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968626.1 1392146 D 580050 CDS YP_002968627.1 241191233 8009158 1394436..1395620 1 NC_012814.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1395620 8009158 Balac_1209 Bifidobacterium animalis subsp. lactis Bl-04 D-3-phosphoglycerate dehydrogenase YP_002968627.1 1394436 D 580050 CDS YP_002968628.1 241191234 8009159 complement(1395677..1396123) 1 NC_012814.1 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR 1396123 8009159 Balac_1210 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator NrdR YP_002968628.1 1395677 R 580050 CDS YP_002968629.1 241191235 8009160 complement(1396218..1396649) 1 NC_012814.1 COG1388 FOG: LysM repeat; hypothetical protein 1396649 8009160 Balac_1211 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968629.1 1396218 R 580050 CDS YP_002968630.1 241191236 8009161 1396706..1397401 1 NC_012814.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1397401 8009161 Balac_1212 Bifidobacterium animalis subsp. lactis Bl-04 LexA repressor YP_002968630.1 1396706 D 580050 CDS YP_002968631.1 241191237 8009162 complement(1397784..1398716) 1 NC_012814.1 COG1230 Co/Zn/Cd efflux system component; cation efflux protein 1398716 8009162 Balac_1213 Bifidobacterium animalis subsp. lactis Bl-04 cation efflux protein YP_002968631.1 1397784 R 580050 CDS YP_002968632.1 241191238 8009163 complement(1398830..1399792) 1 NC_012814.1 COG0039 Malate/lactate dehydrogenases; L-lactate dehydrogenase 2 1399792 8009163 Balac_1214 Bifidobacterium animalis subsp. lactis Bl-04 L-lactate dehydrogenase 2 YP_002968632.1 1398830 R 580050 CDS YP_002968633.1 241191239 8009164 complement(1399967..1401514) 1 NC_012814.1 COG2262 GTPases; GTP-binding protein 1401514 8009164 Balac_1215 Bifidobacterium animalis subsp. lactis Bl-04 GTP-binding protein YP_002968633.1 1399967 R 580050 CDS YP_002968634.1 241191240 8009165 1401618..1402247 1 NC_012814.1 COG2813 16S RNA G1207 methylase RsmC; hypothetical protein 1402247 8009165 Balac_1216 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968634.1 1401618 D 580050 CDS YP_002968635.1 241191241 8009166 1402291..1406337 1 NC_012814.1 COG1643 HrpA-like helicases; ATP-dependent helicase 1406337 8009166 Balac_1217 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent helicase YP_002968635.1 1402291 D 580050 CDS YP_002968636.1 241191242 8009167 complement(1406431..1407768) 1 NC_012814.1 COG0174 Glutamine synthetase; glutamine synthetase 2 1407768 8009167 Balac_1218 Bifidobacterium animalis subsp. lactis Bl-04 glutamine synthetase 2 YP_002968636.1 1406431 R 580050 CDS YP_002968637.1 241191243 8009168 1407949..1409352 1 NC_012814.1 COG4320 Uncharacterized protein conserved in bacteria; hypothetical protein 1409352 8009168 Balac_1219 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968637.1 1407949 D 580050 CDS YP_002968638.1 241191244 8009169 complement(1409472..1410200) 1 NC_012814.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 1410200 8009169 Balac_1220 Bifidobacterium animalis subsp. lactis Bl-04 phosphoribosyl isomerase A YP_002968638.1 1409472 R 580050 CDS YP_002968639.1 241191245 8009170 complement(1410248..1410895) 1 NC_012814.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1410895 hisH 8009170 hisH Bifidobacterium animalis subsp. lactis Bl-04 imidazole glycerol phosphate synthase subunit HisH YP_002968639.1 1410248 R 580050 CDS YP_002968640.1 241191246 8009171 complement(1410926..1411675) 1 NC_012814.1 hypothetical protein 1411675 8009171 Balac_1222 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968640.1 1410926 R 580050 CDS YP_002968641.1 241191247 8009172 complement(1411675..1412277) 1 NC_012814.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1412277 hisB 8009172 hisB Bifidobacterium animalis subsp. lactis Bl-04 imidazoleglycerol-phosphate dehydratase YP_002968641.1 1411675 R 580050 CDS YP_002968642.1 241191248 8009173 complement(1412320..1413486) 1 NC_012814.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1413486 8009173 Balac_1224 Bifidobacterium animalis subsp. lactis Bl-04 histidinol-phosphate aminotransferase YP_002968642.1 1412320 R 580050 CDS YP_002968643.1 241191249 8009174 complement(1413483..1414865) 1 NC_012814.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1414865 hisD 8009174 hisD Bifidobacterium animalis subsp. lactis Bl-04 histidinol dehydrogenase YP_002968643.1 1413483 R 580050 CDS YP_002968644.1 241191250 8009175 complement(1415165..1418731) 1 NC_012814.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1418731 dnaE 8009175 dnaE Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunit alpha YP_002968644.1 1415165 R 580050 CDS YP_002968645.1 241191251 8009176 1418933..1419238 1 NC_012814.1 hypothetical protein 1419238 8009176 Balac_1227 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968645.1 1418933 D 580050 CDS YP_002968646.1 241191252 8009177 complement(1419218..1420171) 1 NC_012814.1 COG0564 Pseudouridylate synthases, 23SRNA-specific; hypothetical protein 1420171 8009177 Balac_1228 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968646.1 1419218 R 580050 CDS YP_002968647.1 241191253 8009178 complement(1420190..1420696) 1 NC_012814.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1420696 8009178 Balac_1229 Bifidobacterium animalis subsp. lactis Bl-04 lipoprotein signal peptidase YP_002968647.1 1420190 R 580050 CDS YP_002968648.1 241191254 8009179 complement(1420745..1422211) 1 NC_012814.1 COG3599 Cell division initiation protein; hypothetical protein 1422211 8009179 Balac_1230 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968648.1 1420745 R 580050 CDS YP_002968649.1 241191255 8009180 complement(1422388..1422678) 1 NC_012814.1 COG0762 Predicted integral membrane protein; hypothetical protein 1422678 8009180 Balac_1231 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968649.1 1422388 R 580050 CDS YP_002968650.1 241191256 8009181 complement(1422760..1423230) 1 NC_012814.1 COG1799 Uncharacterized protein conserved in bacteria; hypothetical protein 1423230 8009181 Balac_1232 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968650.1 1422760 R 580050 CDS YP_002968651.1 241191257 8009182 complement(1423319..1424575) 1 NC_012814.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1424575 8009182 Balac_1233 Bifidobacterium animalis subsp. lactis Bl-04 cell division protein FtsZ YP_002968651.1 1423319 R 580050 CDS YP_002968652.1 241191258 8009183 complement(1424736..1425989) 1 NC_012814.1 COG0042 tRNA-dihydrouridine synthase; NifR3-like protein 1425989 8009183 Balac_1234 Bifidobacterium animalis subsp. lactis Bl-04 NifR3-like protein YP_002968652.1 1424736 R 580050 CDS YP_002968653.1 241191259 8009184 complement(1426120..1427595) 1 NC_012814.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1427595 8009184 Balac_1235 Bifidobacterium animalis subsp. lactis Bl-04 glycyl-tRNA synthetase YP_002968653.1 1426120 R 580050 CDS YP_002968654.1 241191260 8009185 1427837..1428748 1 NC_012814.1 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 1428748 8009185 Balac_1236 Bifidobacterium animalis subsp. lactis Bl-04 hydroxyethylthiazole kinase YP_002968654.1 1427837 D 580050 CDS YP_002968655.1 241191261 8009186 1428801..1430351 1 NC_012814.1 COG0352 Thiamine monophosphate synthase; phosphomethylpyrimidine kinase 1430351 8009186 Balac_1237 Bifidobacterium animalis subsp. lactis Bl-04 phosphomethylpyrimidine kinase YP_002968655.1 1428801 D 580050 CDS YP_002968656.1 241191262 8009187 1430440..1430808 1 NC_012814.1 COG0011 Uncharacterized conserved protein; hypothetical protein 1430808 8009187 Balac_1238 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968656.1 1430440 D 580050 CDS YP_002968657.1 241191263 8009188 1430882..1431940 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 1431940 8009188 Balac_1239 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002968657.1 1430882 D 580050 CDS YP_002968658.1 241191264 8009189 1432238..1433563 1 NC_012814.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 1433563 lacY 8009189 lacY Bifidobacterium animalis subsp. lactis Bl-04 galactoside permease YP_002968658.1 1432238 D 580050 CDS YP_002968659.1 241191265 8009190 1433814..1435412 1 NC_012814.1 COG1621 Beta-fructosidases (levanase/invertase); Sucrose-6-phosphate hydrolase 1435412 8009190 Balac_1241 Bifidobacterium animalis subsp. lactis Bl-04 Sucrose-6-phosphate hydrolase YP_002968659.1 1433814 D 580050 CDS YP_002968660.1 241191266 8009191 1435631..1436443 1 NC_012814.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 1436443 8009191 Balac_1242 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002968660.1 1435631 D 580050 CDS YP_002968661.1 241191267 8009192 1436488..1437570 1 NC_012814.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; ABC transporter substrate-binding protein 1437570 8009192 Balac_1243 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002968661.1 1436488 D 580050 CDS YP_002968662.1 241191268 8009193 1437622..1438857 1 NC_012814.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; Inosine-uridine nucleoside N-ribohydrolase 1438857 8009193 Balac_1244 Bifidobacterium animalis subsp. lactis Bl-04 Inosine-uridine nucleoside N-ribohydrolase YP_002968662.1 1437622 D 580050 CDS YP_002968663.1 241191269 8009194 complement(1438863..1439036) 1 NC_012814.1 hypothetical protein 1439036 8009194 Balac_1245 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968663.1 1438863 R 580050 CDS YP_002968664.1 241191270 8009195 complement(1439243..1440034) 1 NC_012814.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1440034 8009195 Balac_1246 Bifidobacterium animalis subsp. lactis Bl-04 UDP pyrophosphate synthase YP_002968664.1 1439243 R 580050 CDS YP_002968665.1 241191271 8009196 complement(1440039..1440758) 1 NC_012814.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1440758 recO 8009196 recO Bifidobacterium animalis subsp. lactis Bl-04 DNA repair protein RecO YP_002968665.1 1440039 R 580050 CDS YP_002968666.1 241191272 8009197 complement(1440771..1442489) 1 NC_012814.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 1442489 8009197 Balac_1248 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968666.1 1440771 R 580050 CDS YP_002968667.1 241191273 8009198 complement(1442505..1443707) 1 NC_012814.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1443707 ispG 8009198 ispG Bifidobacterium animalis subsp. lactis Bl-04 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002968667.1 1442505 R 580050 CDS YP_002968668.1 241191274 8009199 complement(1443828..1445018) 1 NC_012814.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1445018 8009199 Balac_1250 Bifidobacterium animalis subsp. lactis Bl-04 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002968668.1 1443828 R 580050 CDS YP_002968669.1 241191275 8009200 complement(1445071..1446672) 1 NC_012814.1 hypothetical protein 1446672 8009200 Balac_1251 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968669.1 1445071 R 580050 CDS YP_002968670.1 241191276 8009600 1447042..1447533 1 NC_012814.1 COG1196 Chromosome segregation ATPases; hypothetical protein 1447533 8009600 Balac_1253 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968670.1 1447042 D 580050 CDS YP_002968671.1 241191277 8009202 complement(1447656..1448072) 1 NC_012814.1 COG2303 Choline dehydrogenase and related flavoproteins; hypothetical protein 1448072 8009202 Balac_1254 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968671.1 1447656 R 580050 CDS YP_002968672.1 241191278 8009203 complement(1448178..1449134) 1 NC_012814.1 COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein 1449134 8009203 Balac_1255 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968672.1 1448178 R 580050 CDS YP_002968673.1 241191279 8009204 1449239..1450897 1 NC_012814.1 COG5282 Uncharacterized conserved protein; hypothetical protein 1450897 8009204 Balac_1256 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968673.1 1449239 D 580050 CDS YP_002968674.1 241191280 8009205 complement(1450983..1452572) 1 NC_012814.1 COG0210 Superfamily I DNA and RNA helicases; DNA helicase II 1452572 8009205 Balac_1257 Bifidobacterium animalis subsp. lactis Bl-04 DNA helicase II YP_002968674.1 1450983 R 580050 CDS YP_002968675.1 241191281 8009206 1452740..1454221 1 NC_012814.1 COG3173 Predicted aminoglycosidephosphotransferase; hypothetical protein 1454221 8009206 Balac_1258 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968675.1 1452740 D 580050 CDS YP_002968676.1 241191282 8009207 1454339..1454566 1 NC_012814.1 hypothetical protein 1454566 8009207 Balac_1259 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968676.1 1454339 D 580050 CDS YP_002968677.1 241191283 8009208 complement(1454657..1455541) 1 NC_012814.1 COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein 1455541 8009208 Balac_1260 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968677.1 1454657 R 580050 CDS YP_002968678.1 241191284 8009209 1455717..1456385 1 NC_012814.1 COG4243 Predicted membrane protein; hypothetical protein 1456385 8009209 Balac_1261 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968678.1 1455717 D 580050 CDS YP_002968679.1 241191285 8009210 complement(1456410..1457294) 1 NC_012814.1 COG0253 Diaminopimelate epimerase; diaminopimelate epimerase 1457294 8009210 Balac_1262 Bifidobacterium animalis subsp. lactis Bl-04 diaminopimelate epimerase YP_002968679.1 1456410 R 580050 CDS YP_002968680.1 241191286 8009211 1457434..1458210 1 NC_012814.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1458210 8009211 Balac_1263 Bifidobacterium animalis subsp. lactis Bl-04 glutamate racemase YP_002968680.1 1457434 D 580050 CDS YP_002968681.1 241191287 8009212 1458260..1459117 1 NC_012814.1 COG4667 Predicted esterase of the alpha-betahydrolase superfamily; hypothetical protein 1459117 8009212 Balac_1264 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968681.1 1458260 D 580050 CDS YP_002968682.1 241191288 8009213 complement(1459193..1460101) 1 NC_012814.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 1460101 8009213 Balac_1265 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968682.1 1459193 R 580050 CDS YP_002968683.1 241191289 8009214 complement(1460333..1461241) 1 NC_012814.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein 1461241 8009214 Balac_1266 Bifidobacterium animalis subsp. lactis Bl-04 amino acid ABC transporter substrate-binding protein YP_002968683.1 1460333 R 580050 CDS YP_002968684.1 241191290 8009215 complement(1461290..1462183) 1 NC_012814.1 COG1126 ABC-type polar amino acid transport system, ATPase component; glutamate/aspartate ABC transporter ATP binding protein 1462183 8009215 Balac_1267 Bifidobacterium animalis subsp. lactis Bl-04 glutamate/aspartate ABC transporter ATP binding protein YP_002968684.1 1461290 R 580050 CDS YP_002968685.1 241191291 8009216 complement(1462176..1462850) 1 NC_012814.1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 1462850 8009216 Balac_1268 Bifidobacterium animalis subsp. lactis Bl-04 amino acid ABC transporter permease YP_002968685.1 1462176 R 580050 CDS YP_002968686.1 241191292 8009217 complement(1462837..1463493) 1 NC_012814.1 COG0765 ABC-type amino acid transport system, permease component; ABC transporter permease 1463493 8009217 Balac_1269 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002968686.1 1462837 R 580050 CDS YP_002968687.1 241191293 8009218 complement(1463665..1464849) 1 NC_012814.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; transaminase 1464849 8009218 Balac_1270 Bifidobacterium animalis subsp. lactis Bl-04 transaminase YP_002968687.1 1463665 R 580050 CDS YP_002968688.1 241191294 8009219 complement(1465082..1465741) 1 NC_012814.1 COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter permease 1465741 8009219 Balac_1271 Bifidobacterium animalis subsp. lactis Bl-04 metal ion ABC transporter permease YP_002968688.1 1465082 R 580050 CDS YP_002968689.1 241191295 8009220 complement(1465738..1466922) 1 NC_012814.1 COG1135 ABC-type metal ion transport system, ATPase component; ABC transporter ATP-binding protein 1466922 8009220 Balac_1272 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968689.1 1465738 R 580050 CDS YP_002968690.1 241191296 8009221 complement(1466974..1467870) 1 NC_012814.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; NLPA lipoprotein 1467870 8009221 Balac_1273 Bifidobacterium animalis subsp. lactis Bl-04 NLPA lipoprotein YP_002968690.1 1466974 R 580050 CDS YP_002968691.1 241191297 8009222 complement(1467985..1468995) 1 NC_012814.1 COG1893 Ketopantoate reductase; 2-dehydropantoate 2-reductase 1468995 8009222 Balac_1274 Bifidobacterium animalis subsp. lactis Bl-04 2-dehydropantoate 2-reductase YP_002968691.1 1467985 R 580050 CDS YP_002968692.1 241191298 8009223 1469347..1470006 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 1470006 8009223 Balac_1275 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968692.1 1469347 D 580050 CDS YP_002968693.1 241191299 8009224 1470260..1470826 1 NC_012814.1 COG2176 DNA polymerase III, alpha subunit (gram-positive type); DNA polymerase III subunit alpha 1470826 8009224 Balac_1276 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunit alpha YP_002968693.1 1470260 D 580050 CDS YP_002968694.1 241191300 8009605 complement(1477781..1479751) 1 NC_012814.1 COG0480 Translation elongation factors (GTPases); translation elongation factor 1479751 8009605 Balac_1282 Bifidobacterium animalis subsp. lactis Bl-04 translation elongation factor YP_002968694.1 1477781 R 580050 CDS YP_002968695.1 241191301 8009226 complement(1479781..1481316) 1 NC_012814.1 COG0531 Amino acid transporters; putative arginine/ornithine antiporter 1481316 8009226 Balac_1283 Bifidobacterium animalis subsp. lactis Bl-04 putative arginine/ornithine antiporter YP_002968695.1 1479781 R 580050 CDS YP_002968696.1 241191302 8009227 complement(1481419..1482048) 1 NC_012814.1 hypothetical protein 1482048 8009227 Balac_1284 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968696.1 1481419 R 580050 CDS YP_002968697.1 241191303 8009228 complement(1482193..1482411) 1 NC_012814.1 hypothetical protein 1482411 8009228 Balac_1285 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968697.1 1482193 R 580050 CDS YP_002968698.1 241191304 8009229 1482712..1484382 1 NC_012814.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; ABC transporter 1484382 8009229 Balac_1286 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002968698.1 1482712 D 580050 CDS YP_002968699.1 241191305 8009230 1484389..1485846 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1485846 8009230 Balac_1287 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968699.1 1484389 D 580050 CDS YP_002968700.1 241191306 8009231 complement(1485953..1486651) 1 NC_012814.1 COG1842 Phage shock protein A (IM30, suppresses sigma54-dependent transcription); phage shock protein A-like protein 1486651 8009231 Balac_1288 Bifidobacterium animalis subsp. lactis Bl-04 phage shock protein A-like protein YP_002968700.1 1485953 R 580050 CDS YP_002968701.1 241191307 8009232 complement(1486654..1487889) 1 NC_012814.1 hypothetical protein 1487889 8009232 Balac_1289 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968701.1 1486654 R 580050 CDS YP_002968702.1 241191308 8009233 complement(1488062..1488283) 1 NC_012814.1 hypothetical protein 1488283 8009233 Balac_1290 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968702.1 1488062 R 580050 CDS YP_002968703.1 241191309 8009234 complement(1488518..1491841) 1 NC_012814.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 1491841 ileS 8009234 ileS Bifidobacterium animalis subsp. lactis Bl-04 isoleucyl-tRNA synthetase YP_002968703.1 1488518 R 580050 CDS YP_002968704.1 241191310 8009235 complement(1492283..1492450) 1 NC_012814.1 hypothetical protein 1492450 8009235 Balac_1292 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968704.1 1492283 R 580050 CDS YP_002968705.1 241191311 8009236 complement(1492633..1493403) 1 NC_012814.1 COG2365 Protein tyrosine/serine phosphatase; putative serine/tyrosine protein phosphatase 1493403 8009236 Balac_1293 Bifidobacterium animalis subsp. lactis Bl-04 putative serine/tyrosine protein phosphatase YP_002968705.1 1492633 R 580050 CDS YP_002968706.1 241191312 8009237 complement(1493431..1493721) 1 NC_012814.1 hypothetical protein 1493721 8009237 Balac_1294 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968706.1 1493431 R 580050 CDS YP_002968707.1 241191313 8009238 complement(1493960..1494172) 1 NC_012814.1 hypothetical protein 1494172 8009238 Balac_1295 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968707.1 1493960 R 580050 CDS YP_002968708.1 241191314 8009239 complement(1494331..1496409) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 1496409 8009239 Balac_1296 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter YP_002968708.1 1494331 R 580050 CDS YP_002968709.1 241191315 8009240 complement(1496406..1498379) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1498379 8009240 Balac_1297 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter ATPase and permease YP_002968709.1 1496406 R 580050 CDS YP_002968710.1 241191316 8009241 complement(1498376..1498927) 1 NC_012814.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 1498927 8009241 Balac_1298 Bifidobacterium animalis subsp. lactis Bl-04 MarR family transcriptional regulator YP_002968710.1 1498376 R 580050 CDS YP_002968711.1 241191317 8009242 complement(1499185..1499751) 1 NC_012814.1 COG0431 Predicted flavoprotein; NADPH-dependent reductase 1499751 8009242 Balac_1299 Bifidobacterium animalis subsp. lactis Bl-04 NADPH-dependent reductase YP_002968711.1 1499185 R 580050 CDS YP_002968712.1 241191318 8009243 1499994..1500377 1 NC_012814.1 COG3727 DNA G:T-mismatch repair endonuclease; Vsr endonuclease 1500377 8009243 Balac_1300 Bifidobacterium animalis subsp. lactis Bl-04 Vsr endonuclease YP_002968712.1 1499994 D 580050 CDS YP_002968713.1 241191319 8009244 1501408..1501596 1 NC_012814.1 hypothetical protein 1501596 8009244 Balac_1301 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968713.1 1501408 D 580050 CDS YP_002968714.1 241191320 8009245 1501959..1502219 1 NC_012814.1 hypothetical protein 1502219 8009245 Balac_1302 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968714.1 1501959 D 580050 CDS YP_002968715.1 241191321 8009246 complement(1502290..1503336) 1 NC_012814.1 putative CRISPR-associated Csb3 family protein 1503336 csb3 8009246 csb3 Bifidobacterium animalis subsp. lactis Bl-04 putative CRISPR-associated Csb3 family protein YP_002968715.1 1502290 R 580050 CDS YP_002968716.1 241191322 8009247 complement(1503340..1506393) 1 NC_012814.1 COG1196 Chromosome segregation ATPases; CRISPR-associated helicase Cas3 family protein 1506393 cas3 8009247 cas3 Bifidobacterium animalis subsp. lactis Bl-04 CRISPR-associated helicase Cas3 family protein YP_002968716.1 1503340 R 580050 CDS YP_002968717.1 241191323 8009248 complement(1506384..1508021) 1 NC_012814.1 putative CRISPR-associated Csb2 family protein 1508021 csb2 8009248 csb2 Bifidobacterium animalis subsp. lactis Bl-04 putative CRISPR-associated Csb2 family protein YP_002968717.1 1506384 R 580050 CDS YP_002968718.1 241191324 8009249 complement(1508040..1509233) 1 NC_012814.1 putative CRISPR-associated Csb1 family protein 1509233 csb1 8009249 csb1 Bifidobacterium animalis subsp. lactis Bl-04 putative CRISPR-associated Csb1 family protein YP_002968718.1 1508040 R 580050 CDS YP_002968719.1 241191325 8009250 complement(1509650..1509943) 1 NC_012814.1 COG1343 Uncharacterized protein predicted to beinvolved in DNA repair; CRISPR-associated Cas2 family protein 1509943 cas2 8009250 cas2 Bifidobacterium animalis subsp. lactis Bl-04 CRISPR-associated Cas2 family protein YP_002968719.1 1509650 R 580050 CDS YP_002968720.1 241191326 8009251 complement(1509955..1511445) 1 NC_012814.1 COG1518; COG1468 RecB family exonuclease/transl_table; CRISPR-associated Cas1/Cas4 family protein 1511445 cas1 8009251 cas1 Bifidobacterium animalis subsp. lactis Bl-04 CRISPR-associated Cas1/Cas4 family protein YP_002968720.1 1509955 R 580050 CDS YP_002968721.1 241191327 8009252 complement(1513413..1514564) 1 NC_012814.1 COG3572 Gamma-glutamylcysteine synthetase; Gamma-glutamylcysteine synthetase 1514564 8009252 Balac_1309 Bifidobacterium animalis subsp. lactis Bl-04 Gamma-glutamylcysteine synthetase YP_002968721.1 1513413 R 580050 CDS YP_002968722.1 241191328 8009253 complement(1514758..1519476) 1 NC_012814.1 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); hypothetical protein 1519476 8009253 Balac_1310 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968722.1 1514758 R 580050 CDS YP_002968723.1 241191329 8009254 1519726..1520295 1 NC_012814.1 COG3548 Predicted integral membrane protein; hypothetical protein 1520295 8009254 Balac_1311 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968723.1 1519726 D 580050 CDS YP_002968724.1 241191330 8009255 1520292..1520693 1 NC_012814.1 COG3759 Predicted membrane protein; transmembrane protein 1520693 8009255 Balac_1312 Bifidobacterium animalis subsp. lactis Bl-04 transmembrane protein YP_002968724.1 1520292 D 580050 CDS YP_002968725.1 241191331 8009256 1520956..1521645 1 NC_012814.1 hypothetical protein 1521645 8009256 Balac_1313 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968725.1 1520956 D 580050 CDS YP_002968726.1 241191332 8009257 complement(1521642..1522391) 1 NC_012814.1 COG0602 Organic radical activating enzymes; anaerobic ribonucleoside-triphosphate reductase activating protein 1522391 8009257 Balac_1314 Bifidobacterium animalis subsp. lactis Bl-04 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002968726.1 1521642 R 580050 CDS YP_002968727.1 241191333 8009258 complement(1522733..1525159) 1 NC_012814.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1525159 8009258 Balac_1315 Bifidobacterium animalis subsp. lactis Bl-04 anaerobic ribonucleoside triphosphate reductase YP_002968727.1 1522733 R 580050 CDS YP_002968728.1 241191334 8009259 1525516..1526814 1 NC_012814.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1526814 xseA 8009259 xseA Bifidobacterium animalis subsp. lactis Bl-04 exodeoxyribonuclease VII large subunit YP_002968728.1 1525516 D 580050 CDS YP_002968729.1 241191335 8009260 1526858..1527175 1 NC_012814.1 COG1722 Exonuclease VII small subunit; exonuclease VII small subunit 1527175 8009260 Balac_1317 Bifidobacterium animalis subsp. lactis Bl-04 exonuclease VII small subunit YP_002968729.1 1526858 D 580050 CDS YP_002968730.1 241191336 8009261 complement(1527176..1528201) 1 NC_012814.1 COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein 1528201 8009261 Balac_1318 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968730.1 1527176 R 580050 CDS YP_002968731.1 241191337 8009606 1528554..1529282 1 NC_012814.1 hypothetical protein 1529282 8009606 Balac_1320 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968731.1 1528554 D 580050 CDS YP_002968732.1 241191338 8009263 complement(1529298..1530527) 1 NC_012814.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate aminotransferase 1530527 8009263 Balac_1321 Bifidobacterium animalis subsp. lactis Bl-04 aspartate aminotransferase YP_002968732.1 1529298 R 580050 CDS YP_002968733.1 241191339 8009264 complement(1530553..1531086) 1 NC_012814.1 COG3727 DNA G:T-mismatch repair endonuclease; XorII very-short-patch-repair endonuclease 1531086 8009264 Balac_1322 Bifidobacterium animalis subsp. lactis Bl-04 XorII very-short-patch-repair endonuclease YP_002968733.1 1530553 R 580050 CDS YP_002968734.1 241191340 8009265 1531203..1532771 1 NC_012814.1 hypothetical protein 1532771 8009265 Balac_1323 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968734.1 1531203 D 580050 CDS YP_002968735.1 241191341 8009266 complement(1532805..1534190) 1 NC_012814.1 COG0847 DNA polymerase III, epsilon subunit and related 3-5 exonucleases; DNA polymerase III subunit epsilon 1534190 8009266 Balac_1324 Bifidobacterium animalis subsp. lactis Bl-04 DNA polymerase III subunit epsilon YP_002968735.1 1532805 R 580050 CDS YP_002968736.1 241191342 8009267 complement(1534328..1534981) 1 NC_012814.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1534981 def 8009267 def Bifidobacterium animalis subsp. lactis Bl-04 peptide deformylase YP_002968736.1 1534328 R 580050 CDS YP_002968737.1 241191343 8009268 complement(1535019..1536389) 1 NC_012814.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1536389 glmM 8009268 glmM Bifidobacterium animalis subsp. lactis Bl-04 phosphoglucosamine mutase YP_002968737.1 1535019 R 580050 CDS YP_002968738.1 241191344 8009269 complement(1536848..1539472) 1 NC_012814.1 COG0308 Aminopeptidase N; aminopeptidase 1539472 8009269 Balac_1327 Bifidobacterium animalis subsp. lactis Bl-04 aminopeptidase YP_002968738.1 1536848 R 580050 CDS YP_002968739.1 241191345 8009270 complement(1539629..1541536) 1 NC_012814.1 COG0595 Predicted hydrolase of themetallo-beta-lactamase superfamily; hypothetical protein 1541536 8009270 Balac_1328 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968739.1 1539629 R 580050 CDS YP_002968740.1 241191346 8009271 complement(1541637..1542533) 1 NC_012814.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1542533 8009271 Balac_1329 Bifidobacterium animalis subsp. lactis Bl-04 dihydrodipicolinate synthase YP_002968740.1 1541637 R 580050 CDS YP_002968741.1 241191347 8009272 complement(1542594..1543355) 1 NC_012814.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1543355 8009272 Balac_1330 Bifidobacterium animalis subsp. lactis Bl-04 dihydrodipicolinate reductase YP_002968741.1 1542594 R 580050 CDS YP_002968742.1 241191348 8009273 complement(1543411..1544829) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; transport protein 1544829 8009273 Balac_1331 Bifidobacterium animalis subsp. lactis Bl-04 transport protein YP_002968742.1 1543411 R 580050 CDS YP_002968743.1 241191349 8009274 complement(1544826..1545536) 1 NC_012814.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetylglutamate synthase 1545536 8009274 Balac_1332 Bifidobacterium animalis subsp. lactis Bl-04 N-acetylglutamate synthase YP_002968743.1 1544826 R 580050 CDS YP_002968744.1 241191350 8009275 complement(1545759..1549895) 1 NC_012814.1 COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase 1549895 8009275 Balac_1333 Bifidobacterium animalis subsp. lactis Bl-04 ATP-dependent DNA helicase YP_002968744.1 1545759 R 580050 CDS YP_002968745.1 241191351 8009276 complement(1549908..1554461) 1 NC_012814.1 COG0210 Superfamily I DNA and RNA helicases; hypothetical protein 1554461 8009276 Balac_1334 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968745.1 1549908 R 580050 CDS YP_002968746.1 241191352 8009277 1554796..1556199 1 NC_012814.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 1556199 8009277 Balac_1335 Bifidobacterium animalis subsp. lactis Bl-04 Serine/threonine protein kinase YP_002968746.1 1554796 D 580050 CDS YP_002968747.1 241191353 8009278 1556206..1562127 1 NC_012814.1 COG2931 RTX toxins and related Ca2+-binding proteins; fibronectin type III 1562127 8009278 Balac_1336 Bifidobacterium animalis subsp. lactis Bl-04 fibronectin type III YP_002968747.1 1556206 D 580050 CDS YP_002968748.1 241191354 8009279 1562111..1563349 1 NC_012814.1 COG0714 MoxR-like ATPases; methanol dehydrogenase regulatory protein 1563349 8009279 Balac_1337 Bifidobacterium animalis subsp. lactis Bl-04 methanol dehydrogenase regulatory protein YP_002968748.1 1562111 D 580050 CDS YP_002968749.1 241191355 8009280 1563336..1564529 1 NC_012814.1 COG1721 Uncharacterized conserved protein (somemembers contain a von Willebrand factor type A (vWAdomain)); hypothetical protein 1564529 8009280 Balac_1338 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968749.1 1563336 D 580050 CDS YP_002968750.1 241191356 8009281 1564526..1567015 1 NC_012814.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 1567015 8009281 Balac_1339 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968750.1 1564526 D 580050 CDS YP_002968751.1 241191357 8009282 1567282..1567929 1 NC_012814.1 hypothetical protein 1567929 8009282 Balac_1340 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968751.1 1567282 D 580050 CDS YP_002968752.1 241191358 8009283 complement(1567944..1568570) 1 NC_012814.1 COG1716 FOG: FHA domain; hypothetical protein 1568570 8009283 Balac_1341 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968752.1 1567944 R 580050 CDS YP_002968753.1 241191359 8009284 complement(1568690..1572727) 1 NC_012814.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1572727 8009284 Balac_1342 Bifidobacterium animalis subsp. lactis Bl-04 DNA-directed RNA polymerase subunit beta' YP_002968753.1 1568690 R 580050 CDS YP_002968754.1 241191360 8009285 complement(1572788..1576348) 1 NC_012814.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1576348 rpoB 8009285 rpoB Bifidobacterium animalis subsp. lactis Bl-04 DNA-directed RNA polymerase subunit beta YP_002968754.1 1572788 R 580050 CDS YP_002968755.1 241191361 8009286 complement(1576582..1577247) 1 NC_012814.1 hypothetical protein 1577247 8009286 Balac_1344 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968755.1 1576582 R 580050 CDS YP_002968756.1 241191362 8009287 complement(1577564..1578553) 1 NC_012814.1 COG1194 A/G-specific DNA glycosylase; A/G-specific adenine glycosylase 1578553 8009287 Balac_1345 Bifidobacterium animalis subsp. lactis Bl-04 A/G-specific adenine glycosylase YP_002968756.1 1577564 R 580050 CDS YP_002968757.1 241191363 8009288 1578627..1579298 1 NC_012814.1 COG0219 Predicted rRNA methylase (SpoU class)); hypothetical protein 1579298 8009288 Balac_1346 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968757.1 1578627 D 580050 CDS YP_002968758.1 241191364 8009289 complement(1579423..1580787) 1 NC_012814.1 COG2848 Uncharacterized conserved protein; hypothetical protein 1580787 8009289 Balac_1347 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968758.1 1579423 R 580050 CDS YP_002968759.1 241191365 8009290 complement(1580832..1581104) 1 NC_012814.1 ACT domain-containing protein; hypothetical protein 1581104 8009290 Balac_1348 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968759.1 1580832 R 580050 CDS YP_002968760.1 241191366 8009291 complement(1581229..1582077) 1 NC_012814.1 COG3764 Sortase (surface protein transpeptidase); sortase family protein 1582077 srtB 8009291 srtB Bifidobacterium animalis subsp. lactis Bl-04 sortase family protein YP_002968760.1 1581229 R 580050 CDS YP_002968761.1 241191367 8009292 complement(1582100..1582192) 1 NC_012814.1 hypothetical protein 1582192 8009292 Balac_1350 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968761.1 1582100 R 580050 CDS YP_002968762.1 241191368 8009293 complement(1582358..1583608) 1 NC_012814.1 COG0153 Galactokinase; galactokinase 1583608 8009293 Balac_1351 Bifidobacterium animalis subsp. lactis Bl-04 galactokinase YP_002968762.1 1582358 R 580050 CDS YP_002968763.1 241191369 8009294 complement(1583675..1584955) 1 NC_012814.1 COG1085 Galactose-1-phosphate uridylyltransferase; Galactose-1-phosphate uridylyltransferase 1584955 8009294 Balac_1352 Bifidobacterium animalis subsp. lactis Bl-04 Galactose-1-phosphate uridylyltransferase YP_002968763.1 1583675 R 580050 CDS YP_002968764.1 241191370 8009295 complement(1584955..1585776) 1 NC_012814.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR-type transcriptional regulator 1585776 8009295 Balac_1353 Bifidobacterium animalis subsp. lactis Bl-04 DeoR-type transcriptional regulator YP_002968764.1 1584955 R 580050 CDS YP_002968765.1 241191371 8009296 complement(1585894..1586925) 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; dolichyl-phosphate beta-D-mannosyltransferase 1586925 8009296 Balac_1354 Bifidobacterium animalis subsp. lactis Bl-04 dolichyl-phosphate beta-D-mannosyltransferase YP_002968765.1 1585894 R 580050 CDS YP_002968766.1 241191372 8009297 1587088..1588248 1 NC_012814.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1588248 8009297 Balac_1355 Bifidobacterium animalis subsp. lactis Bl-04 dihydroorotate dehydrogenase 2 YP_002968766.1 1587088 D 580050 CDS YP_002968767.1 241191373 8009298 complement(1588547..1589677) 1 NC_012814.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; NADH-dependent flavin oxidoreductase YqjM 1589677 8009298 Balac_1356 Bifidobacterium animalis subsp. lactis Bl-04 NADH-dependent flavin oxidoreductase YqjM YP_002968767.1 1588547 R 580050 CDS YP_002968768.1 241191374 8009299 complement(1589970..1592174) 1 NC_012814.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase 1592174 8009299 Balac_1357 Bifidobacterium animalis subsp. lactis Bl-04 membrane carboxypeptidase YP_002968768.1 1589970 R 580050 CDS YP_002968769.1 241191375 8009300 complement(1592305..1593066) 1 NC_012814.1 COG0664 cAMP-binding proteins - catabolite geneactivator and regulatory subunit of cAMP-dependent protein kinases; transcriptional regulator 1593066 8009300 Balac_1358 Bifidobacterium animalis subsp. lactis Bl-04 transcriptional regulator YP_002968769.1 1592305 R 580050 CDS YP_002968770.1 241191376 8009301 complement(1593106..1594269) 1 NC_012814.1 COG0095 Lipoate-protein ligase A; lipoate protein ligase 1594269 8009301 Balac_1359 Bifidobacterium animalis subsp. lactis Bl-04 lipoate protein ligase YP_002968770.1 1593106 R 580050 CDS YP_002968771.1 241191377 8009302 complement(1594366..1594830) 1 NC_012814.1 COG2314 Predicted membrane protein; hypothetical protein 1594830 8009302 Balac_1360 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968771.1 1594366 R 580050 CDS YP_002968772.1 241191378 8009303 complement(1595202..1595336) 1 NC_012814.1 hypothetical protein 1595336 8009303 Balac_1361 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968772.1 1595202 R 580050 CDS YP_002968773.1 241191379 8009304 complement(1595412..1596452) 1 NC_012814.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1596452 8009304 Balac_1362 Bifidobacterium animalis subsp. lactis Bl-04 3-isopropylmalate dehydrogenase YP_002968773.1 1595412 R 580050 CDS YP_002968774.1 241191380 8009305 complement(1596620..1599013) 1 NC_012814.1 COG1770 Protease II; protease II 1599013 8009305 Balac_1363 Bifidobacterium animalis subsp. lactis Bl-04 protease II YP_002968774.1 1596620 R 580050 CDS YP_002968775.1 241191381 8009306 complement(1599241..1600752) 1 NC_012814.1 COG4850 Uncharacterized conserved protein; hypothetical protein 1600752 8009306 Balac_1364 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968775.1 1599241 R 580050 CDS YP_002968776.1 241191382 8009307 complement(1600809..1601219) 1 NC_012814.1 COG0509 Glycine cleavage system H protein (lipoate-binding); glycine cleavage system H protein 1601219 8009307 Balac_1365 Bifidobacterium animalis subsp. lactis Bl-04 glycine cleavage system H protein YP_002968776.1 1600809 R 580050 CDS YP_002968777.1 241191383 8009308 complement(1601283..1602392) 1 NC_012814.1 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; hypothetical protein 1602392 8009308 Balac_1366 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968777.1 1601283 R 580050 CDS YP_002968778.1 241191384 8009309 complement(1602392..1603318) 1 NC_012814.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha beta hydrolase 1603318 8009309 Balac_1367 Bifidobacterium animalis subsp. lactis Bl-04 alpha beta hydrolase YP_002968778.1 1602392 R 580050 CDS YP_002968779.1 241191385 8009310 complement(1603398..1604012) 1 NC_012814.1 hypothetical protein 1604012 8009310 Balac_1368 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968779.1 1603398 R 580050 CDS YP_002968780.1 241191386 8009311 1604198..1604593 1 NC_012814.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1604593 8009311 Balac_1369 Bifidobacterium animalis subsp. lactis Bl-04 thioredoxin YP_002968780.1 1604198 D 580050 CDS YP_002968781.1 241191387 8009312 1604894..1605952 1 NC_012814.1 COG3583 Uncharacterized protein conserved in bacteria; hypothetical protein 1605952 8009312 Balac_1370 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968781.1 1604894 D 580050 CDS YP_002968782.1 241191388 8009313 complement(1606229..1607839) 1 NC_012814.1 COG2148 Sugar transferases involved inlipopolysaccharide synthesis; UDP-phosphate sugar phosphotransferase 1607839 8009313 Balac_1371 Bifidobacterium animalis subsp. lactis Bl-04 UDP-phosphate sugar phosphotransferase YP_002968782.1 1606229 R 580050 CDS YP_002968783.1 241191389 8009314 complement(1608102..1608551) 1 NC_012814.1 hypothetical protein 1608551 8009314 Balac_1372 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968783.1 1608102 R 580050 CDS YP_002968784.1 241191390 8009315 1608963..1610402 1 NC_012814.1 COG4713 Predicted membrane protein; hypothetical protein 1610402 8009315 Balac_1373 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968784.1 1608963 D 580050 CDS YP_002968785.1 241191391 8009316 complement(1610386..1611327) 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1611327 8009316 Balac_1374 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968785.1 1610386 R 580050 CDS YP_002968786.1 241191392 8009317 complement(1611471..1613138) 1 NC_012814.1 hypothetical protein 1613138 8009317 Balac_1375 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968786.1 1611471 R 580050 CDS YP_002968787.1 241191393 8009318 complement(1613504..1614394) 1 NC_012814.1 COG1209 dTDP-glucose pyrophosphorylase; dTDP-glucose pyrophosphorylase 1614394 8009318 Balac_1376 Bifidobacterium animalis subsp. lactis Bl-04 dTDP-glucose pyrophosphorylase YP_002968787.1 1613504 R 580050 CDS YP_002968788.1 241191394 8009319 complement(1614408..1615859) 1 NC_012814.1 COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes; dTDP-4-dehydrorhamnose 3,5-epimerase 1615859 8009319 Balac_1377 Bifidobacterium animalis subsp. lactis Bl-04 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002968788.1 1614408 R 580050 CDS YP_002968789.1 241191395 8009320 complement(1615934..1616953) 1 NC_012814.1 COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-D-glucose 4,6-dehydratase 1616953 8009320 Balac_1378 Bifidobacterium animalis subsp. lactis Bl-04 dTDP-D-glucose 4,6-dehydratase YP_002968789.1 1615934 R 580050 CDS YP_002968790.1 241191396 8009321 1617109..1618074 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase-like protein 1618074 8009321 Balac_1379 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase-like protein YP_002968790.1 1617109 D 580050 CDS YP_002968791.1 241191397 8009322 complement(1618076..1619527) 1 NC_012814.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx 1619527 8009322 Balac_1380 Bifidobacterium animalis subsp. lactis Bl-04 flippase Wzx YP_002968791.1 1618076 R 580050 CDS YP_002968792.1 241191398 8009323 complement(1619553..1620440) 1 NC_012814.1 COG1216 Predicted glycosyltransferases; glycosyl transferase family protein 1620440 8009323 Balac_1381 Bifidobacterium animalis subsp. lactis Bl-04 glycosyl transferase family protein YP_002968792.1 1619553 R 580050 CDS YP_002968793.1 241191399 8009324 complement(1620459..1621472) 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 1621472 8009324 Balac_1382 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968793.1 1620459 R 580050 CDS YP_002968794.1 241191400 8009325 complement(1621465..1622811) 1 NC_012814.1 hypothetical protein 1622811 8009325 Balac_1383 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968794.1 1621465 R 580050 CDS YP_002968795.1 241191401 8009326 complement(1622808..1623701) 1 NC_012814.1 COG1216 Predicted glycosyltransferases; glycosyltransferase 1623701 8009326 Balac_1384 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase YP_002968795.1 1622808 R 580050 CDS YP_002968796.1 241191402 8009327 complement(1623714..1624478) 1 NC_012814.1 hypothetical protein 1624478 8009327 Balac_1385 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968796.1 1623714 R 580050 CDS YP_002968797.1 241191403 8009328 complement(1624483..1625370) 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1625370 8009328 Balac_1386 Bifidobacterium animalis subsp. lactis Bl-04 glycosyl transferase family protein YP_002968797.1 1624483 R 580050 CDS YP_002968798.1 241191404 8009329 complement(1625520..1626452) 1 NC_012814.1 polysaccharide biosynthesis protein 1626452 8009329 Balac_1387 Bifidobacterium animalis subsp. lactis Bl-04 polysaccharide biosynthesis protein YP_002968798.1 1625520 R 580050 CDS YP_002968799.1 241191405 8009330 complement(1626517..1627764) 1 NC_012814.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; uridine diphosphate glucose dehydrogenase 1627764 8009330 Balac_1388 Bifidobacterium animalis subsp. lactis Bl-04 uridine diphosphate glucose dehydrogenase YP_002968799.1 1626517 R 580050 CDS YP_002968800.1 241191406 8009331 complement(1627885..1629219) 1 NC_012814.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx 1629219 8009331 Balac_1389 Bifidobacterium animalis subsp. lactis Bl-04 flippase Wzx YP_002968800.1 1627885 R 580050 CDS YP_002968801.1 241191407 8009332 complement(1629369..1630373) 1 NC_012814.1 hypothetical protein 1630373 8009332 Balac_1390 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968801.1 1629369 R 580050 CDS YP_002968802.1 241191408 8009333 complement(1630426..1631289) 1 NC_012814.1 COG1216 Predicted glycosyltransferases; group 2 family glycosyl transferase 1631289 8009333 Balac_1391 Bifidobacterium animalis subsp. lactis Bl-04 group 2 family glycosyl transferase YP_002968802.1 1630426 R 580050 CDS YP_002968803.1 241191409 8009334 complement(1631383..1632918) 1 NC_012814.1 COG2148 Sugar transferases involved inlipopolysaccharide synthesis; galactosyl transferase CpsD 1632918 8009334 Balac_1392 Bifidobacterium animalis subsp. lactis Bl-04 galactosyl transferase CpsD YP_002968803.1 1631383 R 580050 CDS YP_002968804.1 241191410 8009335 1633195..1633536 1 NC_012814.1 hypothetical protein 1633536 8009335 Balac_1393 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968804.1 1633195 D 580050 CDS YP_002968805.1 241191411 8009336 1633609..1635333 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1635333 8009336 Balac_1394 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968805.1 1633609 D 580050 CDS YP_002968806.1 241191412 8009337 complement(1635471..1636787) 1 NC_012814.1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; H(+)-stimulated manganese uptake system protein 1636787 8009337 Balac_1395 Bifidobacterium animalis subsp. lactis Bl-04 H(+)-stimulated manganese uptake system protein YP_002968806.1 1635471 R 580050 CDS YP_002968807.1 241191413 8009338 complement(1636933..1637661) 1 NC_012814.1 hypothetical protein 1637661 8009338 Balac_1396 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968807.1 1636933 R 580050 CDS YP_002968808.1 241191414 8009339 1637820..1638695 1 NC_012814.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1638695 8009339 Balac_1397 Bifidobacterium animalis subsp. lactis Bl-04 pyridoxal biosynthesis lyase PdxS YP_002968808.1 1637820 D 580050 CDS YP_002968809.1 241191415 8009340 1638722..1639372 1 NC_012814.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1639372 8009340 Balac_1398 Bifidobacterium animalis subsp. lactis Bl-04 glutamine amidotransferase subunit PdxT YP_002968809.1 1638722 D 580050 CDS YP_002968810.1 241191416 8009341 1639715..1640851 1 NC_012814.1 COG0451 Nucleoside-diphosphate-sugar epimerases; nucleotide sugar epimerase 1640851 8009341 Balac_1399 Bifidobacterium animalis subsp. lactis Bl-04 nucleotide sugar epimerase YP_002968810.1 1639715 D 580050 CDS YP_002968811.1 241191417 8009342 1640956..1641420 1 NC_012814.1 COG0707 UDP-N-acetylglucosamine: LPSN-acetylglucosamine transferase; polysaccharide biosynthesis protein CpsF 1641420 8009342 Balac_1400 Bifidobacterium animalis subsp. lactis Bl-04 polysaccharide biosynthesis protein CpsF YP_002968811.1 1640956 D 580050 CDS YP_002968812.1 241191418 8009343 1641420..1641920 1 NC_012814.1 COG5017 Uncharacterized conserved protein; glycosyltransferase 28-like protein 1641920 8009343 Balac_1401 Bifidobacterium animalis subsp. lactis Bl-04 glycosyltransferase 28-like protein YP_002968812.1 1641420 D 580050 CDS YP_002968813.1 241191419 8009344 1641998..1642951 1 NC_012814.1 COG1216 Predicted glycosyltransferases; putative glycosyltransferase 1642951 8009344 Balac_1402 Bifidobacterium animalis subsp. lactis Bl-04 putative glycosyltransferase YP_002968813.1 1641998 D 580050 CDS YP_002968814.1 241191420 8009345 1642944..1643780 1 NC_012814.1 COG1216 Predicted glycosyltransferases; glycosyl transferase family protein 1643780 8009345 Balac_1403 Bifidobacterium animalis subsp. lactis Bl-04 glycosyl transferase family protein YP_002968814.1 1642944 D 580050 CDS YP_002968815.1 241191421 8009346 1643966..1645099 1 NC_012814.1 hypothetical protein 1645099 8009346 Balac_1404 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968815.1 1643966 D 580050 CDS YP_002968816.1 241191422 8009347 complement(1645224..1648805) 1 NC_012814.1 COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; multidrug ABC transporter ATPase and permease 1648805 8009347 Balac_1405 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter ATPase and permease YP_002968816.1 1645224 R 580050 CDS YP_002968817.1 241191423 8009348 1649047..1650867 1 NC_012814.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty acid CoA ligase 1650867 8009348 Balac_1406 Bifidobacterium animalis subsp. lactis Bl-04 long-chain-fatty acid CoA ligase YP_002968817.1 1649047 D 580050 CDS YP_002968818.1 241191424 8009349 complement(1650942..1652330) 1 NC_012814.1 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; hypothetical protein 1652330 8009349 Balac_1407 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968818.1 1650942 R 580050 CDS YP_002968819.1 241191425 8009350 1652518..1653084 1 NC_012814.1 COG0394 Protein-tyrosine-phosphatase; hypothetical protein 1653084 8009350 Balac_1408 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968819.1 1652518 D 580050 CDS YP_002968820.1 241191426 8009351 complement(1653169..1654938) 1 NC_012814.1 hypothetical protein 1654938 8009351 Balac_1409 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968820.1 1653169 R 580050 CDS YP_002968821.1 241191427 8009352 complement(1655064..1656536) 1 NC_012814.1 COG3944 Capsular polysaccharide biosynthesis protein; Etk-like tyrosine kinase 1656536 8009352 Balac_1410 Bifidobacterium animalis subsp. lactis Bl-04 Etk-like tyrosine kinase YP_002968821.1 1655064 R 580050 CDS YP_002968822.1 241191428 8009353 1657425..1658279 1 NC_012814.1 hypothetical protein 1658279 8009353 Balac_1411 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968822.1 1657425 D 580050 CDS YP_002968823.1 241191429 8009354 1658410..1658745 1 NC_012814.1 hypothetical protein 1658745 8009354 Balac_1412 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968823.1 1658410 D 580050 CDS YP_002968824.1 241191430 8009355 1659345..1660478 1 NC_012814.1 COG3464 Transposase and in activated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 1660478 8009355 Balac_1413 Bifidobacterium animalis subsp. lactis Bl-04 transposase, IS204/IS1001/IS1096/IS1165 family protein YP_002968824.1 1659345 D 580050 CDS YP_002968825.1 241191431 8009356 complement(1661041..1662024) 1 NC_012814.1 COG0083 Homoserine kinase; homoserine kinase 1662024 8009356 Balac_1414 Bifidobacterium animalis subsp. lactis Bl-04 homoserine kinase YP_002968825.1 1661041 R 580050 CDS YP_002968826.1 241191432 8009357 complement(1662087..1663397) 1 NC_012814.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1663397 8009357 Balac_1415 Bifidobacterium animalis subsp. lactis Bl-04 homoserine dehydrogenase YP_002968826.1 1662087 R 580050 CDS YP_002968827.1 241191433 8009358 complement(1663670..1665259) 1 NC_012814.1 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 1665259 8009358 Balac_1416 Bifidobacterium animalis subsp. lactis Bl-04 diaminopimelate decarboxylase YP_002968827.1 1663670 R 580050 CDS YP_002968828.1 241191434 8009359 complement(1665454..1667226) 1 NC_012814.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1667226 argS 8009359 argS Bifidobacterium animalis subsp. lactis Bl-04 arginyl-tRNA synthetase YP_002968828.1 1665454 R 580050 CDS YP_002968829.1 241191435 8009360 complement(1667490..1668944) 1 NC_012814.1 COG5520 O-Glycosyl hydrolase; glucan endo-1,6-beta-glucosidase 1668944 8009360 Balac_1418 Bifidobacterium animalis subsp. lactis Bl-04 glucan endo-1,6-beta-glucosidase YP_002968829.1 1667490 R 580050 CDS YP_002968830.1 241191436 8009361 complement(1669012..1669410) 1 NC_012814.1 COG0251 Putative translation initiation inhibitor, yjgF family; putative translation initiation inhibitor 1669410 8009361 Balac_1419 Bifidobacterium animalis subsp. lactis Bl-04 putative translation initiation inhibitor YP_002968830.1 1669012 R 580050 CDS YP_002968831.1 241191437 8009362 complement(1669658..1670356) 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; putative sugar transport integral membrane protein 1670356 8009362 Balac_1420 Bifidobacterium animalis subsp. lactis Bl-04 putative sugar transport integral membrane protein YP_002968831.1 1669658 R 580050 CDS YP_002968832.1 241191438 8009363 1670355..1671254 1 NC_012814.1 COG3459 Cellobiose phosphorylase; hypothetical protein 1671254 8009363 Balac_1421 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968832.1 1670355 D 580050 CDS YP_002968833.1 241191439 8009607 complement(1671589..1672542) 1 NC_012814.1 COG3118 Thioredoxin domain-containing protein; hypothetical protein 1672542 8009607 Balac_1423 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968833.1 1671589 R 580050 CDS YP_002968834.1 241191440 8009365 complement(1672609..1673619) 1 NC_012814.1 hypothetical protein 1673619 8009365 Balac_1424 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968834.1 1672609 R 580050 CDS YP_002968835.1 241191441 8009366 complement(1673616..1674965) 1 NC_012814.1 hypothetical protein 1674965 8009366 Balac_1425 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968835.1 1673616 R 580050 CDS YP_002968836.1 241191442 8009367 1675100..1676029 1 NC_012814.1 COG0545 FKBP-type peptidyl-prolyl cis-transisomerases 1; secreted peptidyl-prolyl cis-trans isomeraseprotein 1676029 8009367 Balac_1426 Bifidobacterium animalis subsp. lactis Bl-04 secreted peptidyl-prolyl cis-trans isomeraseprotein YP_002968836.1 1675100 D 580050 CDS YP_002968837.1 241191443 8009368 complement(1676120..1676824) 1 NC_012814.1 COG1637 Predicted nuclease of the RecB family; hypothetical protein 1676824 8009368 Balac_1427 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968837.1 1676120 R 580050 CDS YP_002968838.1 241191444 8009369 complement(1677250..1677558) 1 NC_012814.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit epsilon 1677558 atpC 8009369 atpC Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit epsilon YP_002968838.1 1677250 R 580050 CDS YP_002968839.1 241191445 8009370 complement(1677558..1679045) 1 NC_012814.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1679045 8009370 Balac_1429 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit beta YP_002968839.1 1677558 R 580050 CDS YP_002968840.1 241191446 8009371 complement(1679055..1679975) 1 NC_012814.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1679975 8009371 Balac_1430 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit gamma YP_002968840.1 1679055 R 580050 CDS YP_002968841.1 241191447 8009372 complement(1679979..1681619) 1 NC_012814.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1681619 8009372 Balac_1431 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit alpha YP_002968841.1 1679979 R 580050 CDS YP_002968842.1 241191448 8009373 complement(1681683..1682495) 1 NC_012814.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1682495 8009373 Balac_1432 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit delta YP_002968842.1 1681683 R 580050 CDS YP_002968843.1 241191449 8009374 complement(1682574..1683101) 1 NC_012814.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 1683101 8009374 Balac_1433 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit B YP_002968843.1 1682574 R 580050 CDS YP_002968844.1 241191450 8009375 complement(1683155..1683385) 1 NC_012814.1 COG0636 F0F1-type ATP synthase, subunitc/Archaeal/vacuolar-type H+-ATPase, subunit K; ATP synthase C chain 1683385 8009375 Balac_1434 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase C chain YP_002968844.1 1683155 R 580050 CDS YP_002968845.1 241191451 8009376 complement(1683437..1684249) 1 NC_012814.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 1684249 8009376 Balac_1435 Bifidobacterium animalis subsp. lactis Bl-04 ATP synthase F0F1 subunit A YP_002968845.1 1683437 R 580050 CDS YP_002968846.1 241191452 8009377 complement(1684541..1685569) 1 NC_012814.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1685569 8009377 Balac_1436 Bifidobacterium animalis subsp. lactis Bl-04 homoserine O-succinyltransferase YP_002968846.1 1684541 R 580050 CDS YP_002968847.1 241191453 8009378 complement(1685690..1687120) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1687120 8009378 Balac_1437 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968847.1 1685690 R 580050 CDS YP_002968848.1 241191454 8009379 complement(1687234..1688175) 1 NC_012814.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; hypothetical protein 1688175 8009379 Balac_1438 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968848.1 1687234 R 580050 CDS YP_002968849.1 241191455 8009608 complement(1688611..1689729) 1 NC_012814.1 hypothetical protein 1689729 8009608 Balac_1440 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968849.1 1688611 R 580050 CDS YP_002968850.1 241191456 8009381 1689889..1690074 1 NC_012814.1 hypothetical protein 1690074 8009381 Balac_1441 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968850.1 1689889 D 580050 CDS YP_002968851.1 241191457 8009382 1690181..1690576 1 NC_012814.1 hypothetical protein 1690576 8009382 Balac_1442 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968851.1 1690181 D 580050 CDS YP_002968852.1 241191458 8009383 1690573..1691334 1 NC_012814.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division FtsK/SpoIIIE 1691334 8009383 Balac_1443 Bifidobacterium animalis subsp. lactis Bl-04 cell division FtsK/SpoIIIE YP_002968852.1 1690573 D 580050 CDS YP_002968853.1 241191459 8009384 1691331..1692248 1 NC_012814.1 COG1536 Flagellar motor switch protein; hypothetical protein 1692248 8009384 Balac_1444 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968853.1 1691331 D 580050 CDS YP_002968854.1 241191460 8009385 1692232..1692459 1 NC_012814.1 hypothetical protein 1692459 8009385 Balac_1445 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968854.1 1692232 D 580050 CDS YP_002968855.1 241191461 8009386 complement(1692479..1693597) 1 NC_012814.1 COG1479 Uncharacterized conserved protein; hypothetical protein 1693597 8009386 Balac_1446 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968855.1 1692479 R 580050 CDS YP_002968856.1 241191462 8009387 complement(1693597..1694688) 1 NC_012814.1 modification methylase 1694688 8009387 Balac_1447 Bifidobacterium animalis subsp. lactis Bl-04 modification methylase YP_002968856.1 1693597 R 580050 CDS YP_002968857.1 241191463 8009388 complement(1694766..1695986) 1 NC_012814.1 COG0582 Integrase; hypothetical protein 1695986 8009388 Balac_1448 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968857.1 1694766 R 580050 CDS YP_002968858.1 241191464 8009389 1696590..1697921 1 NC_012814.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 1697921 frc 8009389 frc Bifidobacterium animalis subsp. lactis Bl-04 formyl-coenzyme A transferase YP_002968858.1 1696590 D 580050 CDS YP_002968859.1 241191465 8009390 complement(1698126..1699262) 1 NC_012814.1 COG2730 Endoglucanase; secreted beta-mannosidase 1699262 8009390 Balac_1450 Bifidobacterium animalis subsp. lactis Bl-04 secreted beta-mannosidase YP_002968859.1 1698126 R 580050 CDS YP_002968860.1 241191466 8009391 1699987..1700118 1 NC_012814.1 hypothetical protein 1700118 8009391 Balac_1451 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968860.1 1699987 D 580050 CDS YP_002968861.1 241191467 8009392 complement(1700126..1701229) 1 NC_012814.1 COG0679 Predicted permeases; permease 1701229 8009392 Balac_1452 Bifidobacterium animalis subsp. lactis Bl-04 permease YP_002968861.1 1700126 R 580050 CDS YP_002968862.1 241191468 8009393 complement(1701334..1702911) 1 NC_012814.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome, glyoxylate carboligase, phosphonopyruvatedecarboxylase)]; putative oxalyl-CoA decarboxylase 1702911 oxc 8009393 oxc Bifidobacterium animalis subsp. lactis Bl-04 putative oxalyl-CoA decarboxylase YP_002968862.1 1701334 R 580050 CDS YP_002968863.1 241191469 8009394 complement(1702908..1703114) 1 NC_012814.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome, glyoxylate carboligase, phosphonopyruvatedecarboxylase)]; putative oxalyl-CoA decarboxylase 1703114 8009394 Balac_1454 Bifidobacterium animalis subsp. lactis Bl-04 putative oxalyl-CoA decarboxylase YP_002968863.1 1702908 R 580050 CDS YP_002968864.1 241191470 8009395 complement(1703308..1704966) 1 NC_012814.1 COG0038 Chloride channel protein EriC; voltage gated chloride channel family protein 1704966 8009395 Balac_1455 Bifidobacterium animalis subsp. lactis Bl-04 voltage gated chloride channel family protein YP_002968864.1 1703308 R 580050 CDS YP_002968865.1 241191471 8009396 complement(1705164..1710422) 1 NC_012814.1 COG4932 Predicted outer membrane protein; collagen adhesion protein 1710422 capA 8009396 capA Bifidobacterium animalis subsp. lactis Bl-04 collagen adhesion protein YP_002968865.1 1705164 R 580050 CDS YP_002968866.1 241191472 8009397 complement(1710514..1712589) 1 NC_012814.1 hypothetical protein 1712589 8009397 Balac_1457 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968866.1 1710514 R 580050 CDS YP_002968867.1 241191473 8009398 1712938..1715133 1 NC_012814.1 COG0366 Glycosidases; Trehalose-6-phosphate hydrolase 1715133 8009398 Balac_1458 Bifidobacterium animalis subsp. lactis Bl-04 Trehalose-6-phosphate hydrolase YP_002968867.1 1712938 D 580050 CDS YP_002968868.1 241191474 8009399 1715253..1715762 1 NC_012814.1 COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 1715762 8009399 Balac_1459 Bifidobacterium animalis subsp. lactis Bl-04 inorganic pyrophosphatase YP_002968868.1 1715253 D 580050 CDS YP_002968869.1 241191475 8009400 complement(1715807..1716655) 1 NC_012814.1 hypothetical protein 1716655 8009400 Balac_1460 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968869.1 1715807 R 580050 CDS YP_002968870.1 241191476 8009401 1716966..1717715 1 NC_012814.1 COG0745 Response regulators consisting of aCheY-like receiver domain and a winged-helix DNA-binding domain; hypothetical protein 1717715 8009401 Balac_1461 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968870.1 1716966 D 580050 CDS YP_002968871.1 241191477 8009402 1717795..1718538 1 NC_012814.1 COG0177 Predicted EndoIII-related endonuclease; putative EndoIII-related endonuclease 1718538 8009402 Balac_1462 Bifidobacterium animalis subsp. lactis Bl-04 putative EndoIII-related endonuclease YP_002968871.1 1717795 D 580050 CDS YP_002968872.1 241191478 8009403 1718941..1719036 1 NC_012814.1 hypothetical protein 1719036 8009403 Balac_1463 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968872.1 1718941 D 580050 CDS YP_002968873.1 241191479 8009404 1719118..1720653 1 NC_012814.1 COG0747 ABC-type dipeptide transport system, periplasmic component; ABC transporter substrate-binding protein 1720653 8009404 Balac_1464 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002968873.1 1719118 D 580050 CDS YP_002968874.1 241191480 8009405 1720717..1723509 1 NC_012814.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1723509 valS 8009405 valS Bifidobacterium animalis subsp. lactis Bl-04 valyl-tRNA synthetase YP_002968874.1 1720717 D 580050 CDS YP_002968875.1 241191481 8009406 1723727..1724206 1 NC_012814.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 1724206 8009406 Balac_1466 Bifidobacterium animalis subsp. lactis Bl-04 AsnC family transcriptional regulator YP_002968875.1 1723727 D 580050 CDS YP_002968876.1 241191482 8009407 1724277..1724666 1 NC_012814.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1724666 8009407 Balac_1467 Bifidobacterium animalis subsp. lactis Bl-04 chorismate mutase YP_002968876.1 1724277 D 580050 CDS YP_002968877.1 241191483 8009408 1724741..1726705 1 NC_012814.1 hypothetical protein 1726705 8009408 Balac_1468 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968877.1 1724741 D 580050 CDS YP_002968878.1 241191484 8009409 complement(1726794..1728797) 1 NC_012814.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1728797 8009409 Balac_1469 Bifidobacterium animalis subsp. lactis Bl-04 transcription termination factor Rho YP_002968878.1 1726794 R 580050 CDS YP_002968879.1 241191485 8009410 complement(1729020..1730636) 1 NC_012814.1 COG1232 Protoporphyrinogen oxidase; hypothetical protein 1730636 8009410 Balac_1470 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968879.1 1729020 R 580050 CDS YP_002968880.1 241191486 8009411 complement(1730815..1731129) 1 NC_012814.1 hypothetical protein 1731129 8009411 Balac_1471 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968880.1 1730815 R 580050 CDS YP_002968881.1 241191487 8009412 complement(1731138..1732181) 1 NC_012814.1 COG1670 Acetyltransferases, including N-acetylasesof ribosomal proteins; acetyltransferase 1732181 8009412 Balac_1472 Bifidobacterium animalis subsp. lactis Bl-04 acetyltransferase YP_002968881.1 1731138 R 580050 CDS YP_002968882.1 241191488 8009413 complement(1732606..1734105) 1 NC_012814.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1734105 gatB 8009413 gatB Bifidobacterium animalis subsp. lactis Bl-04 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002968882.1 1732606 R 580050 CDS YP_002968883.1 241191489 8009414 complement(1734126..1735670) 1 NC_012814.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1735670 gatA 8009414 gatA Bifidobacterium animalis subsp. lactis Bl-04 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002968883.1 1734126 R 580050 CDS YP_002968884.1 241191490 8009415 complement(1735672..1735935) 1 NC_012814.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1735935 gatC 8009415 gatC Bifidobacterium animalis subsp. lactis Bl-04 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002968884.1 1735672 R 580050 CDS YP_002968885.1 241191491 8009416 complement(1736090..1736887) 1 NC_012814.1 hypothetical protein 1736887 8009416 Balac_1476 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968885.1 1736090 R 580050 CDS YP_002968886.1 241191492 8009417 complement(1737034..1737819) 1 NC_012814.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 1737819 8009417 Balac_1477 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter ATP-binding protein YP_002968886.1 1737034 R 580050 CDS YP_002968887.1 241191493 8009418 complement(1738054..1738863) 1 NC_012814.1 COG0566 rRNA methylases; hypothetical protein 1738863 8009418 Balac_1478 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968887.1 1738054 R 580050 CDS YP_002968888.1 241191494 8009419 complement(1738909..1739571) 1 NC_012814.1 COG0461 Orotate phosphoribosyltransferase; hypothetical protein 1739571 8009419 Balac_1479 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968888.1 1738909 R 580050 CDS YP_002968889.1 241191495 8009420 1739704..1741110 1 NC_012814.1 COG2217 Cation transport ATPase; copper-transporting ATPase 1741110 8009420 Balac_1480 Bifidobacterium animalis subsp. lactis Bl-04 copper-transporting ATPase YP_002968889.1 1739704 D 580050 CDS YP_002968890.1 241191496 8009421 complement(1741204..1743891) 1 NC_012814.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-binding subunit of Clp protease 1743891 clpB 8009421 clpB Bifidobacterium animalis subsp. lactis Bl-04 ATP-binding subunit of Clp protease YP_002968890.1 1741204 R 580050 CDS YP_002968891.1 241191497 8009422 complement(1744138..1744959) 1 NC_012814.1 COG0179 2-keto-4-pentenoatehydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1744959 8009422 Balac_1482 Bifidobacterium animalis subsp. lactis Bl-04 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase YP_002968891.1 1744138 R 580050 CDS YP_002968892.1 241191498 8009423 complement(1744970..1745488) 1 NC_012814.1 hypothetical protein 1745488 8009423 Balac_1483 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968892.1 1744970 R 580050 CDS YP_002968893.1 241191499 8009424 complement(1745680..1747362) 1 NC_012814.1 cell surface protein fimA fimbrial subunit 1747362 capB 8009424 capB Bifidobacterium animalis subsp. lactis Bl-04 cell surface protein fimA fimbrial subunit YP_002968893.1 1745680 R 580050 CDS YP_002968894.1 241191500 8009425 complement(1747557..1749572) 1 NC_012814.1 hypothetical protein 1749572 srtA 8009425 srtA Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968894.1 1747557 R 580050 CDS YP_002968895.1 241191501 8009426 complement(1750474..1751502) 1 NC_012814.1 COG3764 Sortase (surface protein transpeptidase); Sortase 1751502 8009426 Balac_1486 Bifidobacterium animalis subsp. lactis Bl-04 Sortase YP_002968895.1 1750474 R 580050 CDS YP_002968896.1 241191502 8009427 complement(1751545..1752390) 1 NC_012814.1 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 1752390 8009427 Balac_1487 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968896.1 1751545 R 580050 CDS YP_002968897.1 241191503 8009428 complement(1752505..1753521) 1 NC_012814.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-Q tRNA 1753521 8009428 Balac_1488 Bifidobacterium animalis subsp. lactis Bl-04 glutamyl-Q tRNA YP_002968897.1 1752505 R 580050 CDS YP_002968898.1 241191504 8009429 complement(1753521..1754432) 1 NC_012814.1 membrane protein 1754432 8009429 Balac_1489 Bifidobacterium animalis subsp. lactis Bl-04 membrane protein YP_002968898.1 1753521 R 580050 CDS YP_002968899.1 241191505 8009430 complement(1754588..1755322) 1 NC_012814.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein 1755322 8009430 Balac_1490 Bifidobacterium animalis subsp. lactis Bl-04 glycerol uptake facilitator protein YP_002968899.1 1754588 R 580050 CDS YP_002968900.1 241191506 8009431 complement(1755478..1755837) 1 NC_012814.1 hypothetical protein 1755837 8009431 Balac_1491 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968900.1 1755478 R 580050 CDS YP_002968901.1 241191507 8009432 complement(1756081..1756188) 1 NC_012814.1 hypothetical protein 1756188 8009432 Balac_1492 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968901.1 1756081 R 580050 CDS YP_002968902.1 241191508 8009609 complement(1756631..1757194) 1 NC_012814.1 hypothetical protein 1757194 8009609 Balac_1494 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968902.1 1756631 R 580050 CDS YP_002968903.1 241191509 8009434 1757238..1757447 1 NC_012814.1 hypothetical protein 1757447 8009434 Balac_1495 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968903.1 1757238 D 580050 CDS YP_002968904.1 241191510 8009435 complement(1757753..1758199) 1 NC_012814.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1758199 rplI 8009435 rplI Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L9 YP_002968904.1 1757753 R 580050 CDS YP_002968905.1 241191511 8009436 complement(1758220..1758468) 1 NC_012814.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1758468 rpsR 8009436 rpsR Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S18 YP_002968905.1 1758220 R 580050 CDS YP_002968906.1 241191512 8009437 complement(1758516..1759148) 1 NC_012814.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1759148 8009437 Balac_1498 Bifidobacterium animalis subsp. lactis Bl-04 single-stranded DNA-binding protein YP_002968906.1 1758516 R 580050 CDS YP_002968907.1 241191513 8009438 complement(1759186..1759473) 1 NC_012814.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1759473 rpsF 8009438 rpsF Bifidobacterium animalis subsp. lactis Bl-04 30S ribosomal protein S6 YP_002968907.1 1759186 R 580050 CDS YP_002968908.1 241191514 8009439 1759710..1760681 1 NC_012814.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1760681 8009439 Balac_1500 Bifidobacterium animalis subsp. lactis Bl-04 ribose-phosphate pyrophosphokinase YP_002968908.1 1759710 D 580050 CDS YP_002968909.1 241191515 8009440 complement(1761002..1761970) 1 NC_012814.1 COG0524 Sugar kinases, ribokinase family; PfkB family sugar kinase 1761970 8009440 Balac_1501 Bifidobacterium animalis subsp. lactis Bl-04 PfkB family sugar kinase YP_002968909.1 1761002 R 580050 CDS YP_002968910.1 241191516 8009441 complement(1762073..1763551) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; tetracycline repressor protein 1763551 8009441 Balac_1502 Bifidobacterium animalis subsp. lactis Bl-04 tetracycline repressor protein YP_002968910.1 1762073 R 580050 CDS YP_002968911.1 241191517 8009442 complement(1763634..1764587) 1 NC_012814.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; putative nucleoside hydrolase protein 1764587 8009442 Balac_1503 Bifidobacterium animalis subsp. lactis Bl-04 putative nucleoside hydrolase protein YP_002968911.1 1763634 R 580050 CDS YP_002968912.1 241191518 8009443 complement(1764770..1765747) 1 NC_012814.1 COG1609 Transcriptional regulators; ribose operon repressor RbsR 1765747 8009443 Balac_1504 Bifidobacterium animalis subsp. lactis Bl-04 ribose operon repressor RbsR YP_002968912.1 1764770 R 580050 CDS YP_002968913.1 241191519 8009612 complement(1772075..1773259) 1 NC_012814.1 COG0562 UDP-galactopyranose mutase; UDP-galactopyranose mutase 1773259 8009612 Balac_1508 Bifidobacterium animalis subsp. lactis Bl-04 UDP-galactopyranose mutase YP_002968913.1 1772075 R 580050 CDS YP_002968914.1 241191520 8009445 1773480..1774565 1 NC_012814.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1774565 8009445 Balac_1509 Bifidobacterium animalis subsp. lactis Bl-04 glycosyl transferase family protein YP_002968914.1 1773480 D 580050 CDS YP_002968915.1 241191521 8009446 1774705..1774803 1 NC_012814.1 hypothetical protein 1774803 8009446 Balac_1510 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968915.1 1774705 D 580050 CDS YP_002968916.1 241191522 8009447 complement(1774810..1775778) 1 NC_012814.1 COG1216 Predicted glycosyltransferases; putative glycosyl transferase 1775778 8009447 Balac_1511 Bifidobacterium animalis subsp. lactis Bl-04 putative glycosyl transferase YP_002968916.1 1774810 R 580050 CDS YP_002968917.1 241191523 8009448 1775984..1778125 1 NC_012814.1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Phosphoglycerol transferase 1778125 8009448 Balac_1512 Bifidobacterium animalis subsp. lactis Bl-04 Phosphoglycerol transferase YP_002968917.1 1775984 D 580050 CDS YP_002968918.1 241191524 8009449 1778190..1778297 1 NC_012814.1 hypothetical protein 1778297 8009449 Balac_1513 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968918.1 1778190 D 580050 CDS YP_002968919.1 241191525 8009450 1778311..1780635 1 NC_012814.1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Phosphoglycerol transferase 1780635 8009450 Balac_1514 Bifidobacterium animalis subsp. lactis Bl-04 Phosphoglycerol transferase YP_002968919.1 1778311 D 580050 CDS YP_002968920.1 241191526 8009451 1780647..1782701 1 NC_012814.1 COG1216 Predicted glycosyltransferases; hypothetical protein 1782701 8009451 Balac_1515 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968920.1 1780647 D 580050 CDS YP_002968921.1 241191527 8009452 complement(1782789..1783568) 1 NC_012814.1 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); 1,4-beta-N-acetylmuramidase 1783568 8009452 Balac_1516 Bifidobacterium animalis subsp. lactis Bl-04 1,4-beta-N-acetylmuramidase YP_002968921.1 1782789 R 580050 CDS YP_002968922.1 241191528 8009453 complement(1783751..1785358) 1 NC_012814.1 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); 1,4-beta-N-acetylmuramidase 1785358 8009453 Balac_1517 Bifidobacterium animalis subsp. lactis Bl-04 1,4-beta-N-acetylmuramidase YP_002968922.1 1783751 R 580050 CDS YP_002968923.1 241191529 8009454 1785872..1786789 1 NC_012814.1 COG3328 Transposase and inactivated derivatives; transposase 1786789 8009454 Balac_1518 Bifidobacterium animalis subsp. lactis Bl-04 transposase YP_002968923.1 1785872 D 580050 CDS YP_002968924.1 241191530 8009455 1786919..1787476 1 NC_012814.1 COG4886 Leucine-rich repeat (LRR protein); N-acetylmuramoyl-L-alanine amidase 1787476 8009455 Balac_1519 Bifidobacterium animalis subsp. lactis Bl-04 N-acetylmuramoyl-L-alanine amidase YP_002968924.1 1786919 D 580050 CDS YP_002968925.1 241191531 8009456 1787537..1788064 1 NC_012814.1 Allergen V5/Tpx-1 family protein 1788064 8009456 Balac_1520 Bifidobacterium animalis subsp. lactis Bl-04 Allergen V5/Tpx-1 family protein YP_002968925.1 1787537 D 580050 CDS YP_002968926.1 241191532 8009457 complement(1788216..1788917) 1 NC_012814.1 hypothetical protein 1788917 8009457 Balac_1521 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968926.1 1788216 R 580050 CDS YP_002968927.1 241191533 8009458 complement(1788937..1790265) 1 NC_012814.1 hypothetical protein 1790265 8009458 Balac_1522 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968927.1 1788937 R 580050 CDS YP_002968928.1 241191534 8009459 complement(1790289..1791704) 1 NC_012814.1 COG1134 ABC-type polysaccharide/polyol phosphatetransport system, ATPase component; ATP-driven polysaccharide export protein 1791704 8009459 Balac_1523 Bifidobacterium animalis subsp. lactis Bl-04 ATP-driven polysaccharide export protein YP_002968928.1 1790289 R 580050 CDS YP_002968929.1 241191535 8009460 complement(1791704..1792495) 1 NC_012814.1 COG1682 ABC-type polysaccharide/polyol phosphateexport systems, permease component; polysaccharide ABC transporter permease 1792495 8009460 Balac_1524 Bifidobacterium animalis subsp. lactis Bl-04 polysaccharide ABC transporter permease YP_002968929.1 1791704 R 580050 CDS YP_002968930.1 241191536 8009461 1792721..1794667 1 NC_012814.1 COG1216 Predicted glycosyltransferases; hypothetical protein 1794667 8009461 Balac_1525 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968930.1 1792721 D 580050 CDS YP_002968931.1 241191537 8009613 complement(1794958..1797141) 1 NC_012814.1 hypothetical protein 1797141 8009613 Balac_1527 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968931.1 1794958 R 580050 CDS YP_002968932.1 241191538 8009463 complement(1797204..1799453) 1 NC_012814.1 putative PMT family glycosyltransferase 1799453 8009463 Balac_1528 Bifidobacterium animalis subsp. lactis Bl-04 putative PMT family glycosyltransferase YP_002968932.1 1797204 R 580050 CDS YP_002968933.1 241191539 8009464 1799596..1799694 1 NC_012814.1 hypothetical protein 1799694 8009464 Balac_1529 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968933.1 1799596 D 580050 CDS YP_002968934.1 241191540 8009465 complement(1799744..1801375) 1 NC_012814.1 putative riboflavin-specific deaminase 1801375 8009465 Balac_1530 Bifidobacterium animalis subsp. lactis Bl-04 putative riboflavin-specific deaminase YP_002968934.1 1799744 R 580050 CDS YP_002968935.1 241191541 8009466 1801719..1803059 1 NC_012814.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 1803059 8009466 Balac_1531 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002968935.1 1801719 D 580050 CDS YP_002968936.1 241191542 8009467 1803061..1804125 1 NC_012814.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 1804125 8009467 Balac_1532 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter ATP-binding protein YP_002968936.1 1803061 D 580050 CDS YP_002968937.1 241191543 8009468 complement(1804318..1805106) 1 NC_012814.1 COG1418 Predicted HD superfamily hydrolase; hypothetical protein 1805106 8009468 Balac_1533 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968937.1 1804318 R 580050 CDS YP_002968938.1 241191544 8009469 complement(1805345..1806247) 1 NC_012814.1 COG0121 Predicted glutamine amidotransferase; hypothetical protein 1806247 8009469 Balac_1534 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968938.1 1805345 R 580050 CDS YP_002968939.1 241191545 8009470 complement(1806528..1808720) 1 NC_012814.1 COG3158 K+ transporter; potassium transport system protein kup 2 1808720 8009470 Balac_1535 Bifidobacterium animalis subsp. lactis Bl-04 potassium transport system protein kup 2 YP_002968939.1 1806528 R 580050 CDS YP_002968940.1 241191546 8009471 complement(1808926..1809882) 1 NC_012814.1 COG0084 Mg-dependent DNase; hypothetical protein 1809882 8009471 Balac_1536 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968940.1 1808926 R 580050 CDS YP_002968941.1 241191547 8009472 complement(1810053..1812449) 1 NC_012814.1 COG3345 Alpha-galactosidase; alpha-galactosidase 1812449 8009472 Balac_1537 Bifidobacterium animalis subsp. lactis Bl-04 alpha-galactosidase YP_002968941.1 1810053 R 580050 CDS YP_002968942.1 241191548 8007992 complement(1812527..1813240) 1 NC_012814.1 hypothetical protein 1813240 8007992 Balac_1538 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968942.1 1812527 R 580050 CDS YP_002968943.1 241191549 8009473 complement(1813438..1815231) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1815231 8009473 Balac_1539 Bifidobacterium animalis subsp. lactis Bl-04 multidrug ABC transporter ATPase and permease YP_002968943.1 1813438 R 580050 CDS YP_002968944.1 241191550 8009474 complement(1815340..1817136) 1 NC_012814.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease 1817136 8009474 Balac_1540 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002968944.1 1815340 R 580050 CDS YP_002968945.1 241191551 8009475 complement(1817151..1817255) 1 NC_012814.1 hypothetical protein 1817255 8009475 Balac_1541 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968945.1 1817151 R 580050 CDS YP_002968946.1 241191552 8009476 complement(1818106..1819965) 1 NC_012814.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1819965 8009476 Balac_1542 Bifidobacterium animalis subsp. lactis Bl-04 methionyl-tRNA synthetase YP_002968946.1 1818106 R 580050 CDS YP_002968947.1 241191553 8009477 1820235..1820918 1 NC_012814.1 hypothetical protein 1820918 8009477 Balac_1543 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968947.1 1820235 D 580050 CDS YP_002968948.1 241191554 8009478 1820953..1821399 1 NC_012814.1 hypothetical protein 1821399 8009478 Balac_1544 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968948.1 1820953 D 580050 CDS YP_002968949.1 241191555 8009479 complement(1821434..1822381) 1 NC_012814.1 COG0313 Predicted methyltransferases; hypothetical protein 1822381 8009479 Balac_1545 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968949.1 1821434 R 580050 CDS YP_002968950.1 241191556 8009480 1822539..1824152 1 NC_012814.1 COG1928 Dolichyl-phosphate-mannose--proteinO-mannosyl transferase; glycosyl transferase family protein 1824152 8009480 Balac_1546 Bifidobacterium animalis subsp. lactis Bl-04 glycosyl transferase family protein YP_002968950.1 1822539 D 580050 CDS YP_002968951.1 241191557 8009481 1824703..1825524 1 NC_012814.1 COG0657 Esterase/lipase; xylan esterase 1825524 8009481 Balac_1547 Bifidobacterium animalis subsp. lactis Bl-04 xylan esterase YP_002968951.1 1824703 D 580050 CDS YP_002968952.1 241191558 8009482 1825845..1826594 1 NC_012814.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1826594 8009482 Balac_1548 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968952.1 1825845 D 580050 CDS YP_002968953.1 241191559 8009614 complement(1826910..1827653) 1 NC_012814.1 COG4832 Uncharacterized conserved protein; hypothetical protein 1827653 8009614 Balac_1550 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968953.1 1826910 R 580050 CDS YP_002968954.1 241191560 8009484 complement(1827654..1829984) 1 NC_012814.1 COG1472 Beta-glucosidase-related glycosidases; beta-D-glucosideglucohydrolase 1829984 8009484 Balac_1551 Bifidobacterium animalis subsp. lactis Bl-04 beta-D-glucosideglucohydrolase YP_002968954.1 1827654 R 580050 CDS YP_002968955.1 241191561 8009485 complement(1830107..1830745) 1 NC_012814.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1830745 8009485 Balac_1552 Bifidobacterium animalis subsp. lactis Bl-04 TetR family transcriptional regulator YP_002968955.1 1830107 R 580050 CDS YP_002968956.1 241191562 8009486 complement(1831001..1831687) 1 NC_012814.1 COG0637 Predicted phosphatase/phosphohexomutase; hypothetical protein 1831687 8009486 Balac_1553 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968956.1 1831001 R 580050 CDS YP_002968957.1 241191563 8009487 complement(1831792..1832307) 1 NC_012814.1 COG0789 Predicted transcriptional regulators; MerR-type-transcriptional regulator HsrP 1832307 8009487 Balac_1554 Bifidobacterium animalis subsp. lactis Bl-04 MerR-type-transcriptional regulator HsrP YP_002968957.1 1831792 R 580050 CDS YP_002968958.1 241191564 8009488 complement(1832352..1833407) 1 NC_012814.1 COG2214 DnaJ-class molecular chaperone; molecular chaperone DnaJ 1833407 dnaJ 8009488 dnaJ Bifidobacterium animalis subsp. lactis Bl-04 molecular chaperone DnaJ YP_002968958.1 1832352 R 580050 CDS YP_002968959.1 241191565 8009489 complement(1833538..1834227) 1 NC_012814.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1834227 grpE 8009489 grpE Bifidobacterium animalis subsp. lactis Bl-04 heat shock protein GrpE YP_002968959.1 1833538 R 580050 CDS YP_002968960.1 241191566 8009490 complement(1834227..1836092) 1 NC_012814.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1836092 dnaK 8009490 dnaK Bifidobacterium animalis subsp. lactis Bl-04 molecular chaperone DnaK YP_002968960.1 1834227 R 580050 CDS YP_002968961.1 241191567 8009491 complement(1836229..1836384) 1 NC_012814.1 hypothetical protein 1836384 8009491 Balac_1558 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968961.1 1836229 R 580050 CDS YP_002968962.1 241191568 8009492 complement(1836845..1837870) 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 1837870 8009492 Balac_1559 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002968962.1 1836845 R 580050 CDS YP_002968963.1 241191569 8009493 complement(1837910..1838683) 1 NC_012814.1 putative ABC transporter membrane protein 1838683 8009493 Balac_1560 Bifidobacterium animalis subsp. lactis Bl-04 putative ABC transporter membrane protein YP_002968963.1 1837910 R 580050 CDS YP_002968964.1 241191570 8009494 complement(1838699..1839502) 1 NC_012814.1 COG1011 Predicted hydrolase (HAD superfamily); halo acid dehalogenase-like hydrolase 1839502 8009494 Balac_1561 Bifidobacterium animalis subsp. lactis Bl-04 halo acid dehalogenase-like hydrolase YP_002968964.1 1838699 R 580050 CDS YP_002968965.1 241191571 8009495 complement(1839492..1841591) 1 NC_012814.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; pullulanase 1841591 8009495 Balac_1562 Bifidobacterium animalis subsp. lactis Bl-04 pullulanase YP_002968965.1 1839492 R 580050 CDS YP_002968966.1 241191572 8009496 complement(1841596..1842564) 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; putative sugar ABC transporter membrane protein 1842564 8009496 Balac_1563 Bifidobacterium animalis subsp. lactis Bl-04 putative sugar ABC transporter membrane protein YP_002968966.1 1841596 R 580050 CDS YP_002968967.1 241191573 8009497 complement(1842561..1843934) 1 NC_012814.1 COG1175 ABC-type sugar transport systems, permease components; putative sugar ABC transporter membrane protein 1843934 8009497 Balac_1564 Bifidobacterium animalis subsp. lactis Bl-04 putative sugar ABC transporter membrane protein YP_002968967.1 1842561 R 580050 CDS YP_002968968.1 241191574 8009498 complement(1844254..1845513) 1 NC_012814.1 COG2182 Maltose-binding periplasmic proteins/domains; putative sugar-binding secreted protein 1845513 8009498 Balac_1565 Bifidobacterium animalis subsp. lactis Bl-04 putative sugar-binding secreted protein YP_002968968.1 1844254 R 580050 CDS YP_002968969.1 241191575 8009499 1845783..1847387 1 NC_012814.1 COG0366 Glycosidases; glycosylase 1847387 8009499 Balac_1566 Bifidobacterium animalis subsp. lactis Bl-04 glycosylase YP_002968969.1 1845783 D 580050 CDS YP_002968970.1 241191576 8009500 1847833..1850031 1 NC_012814.1 COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 1850031 8009500 Balac_1567 Bifidobacterium animalis subsp. lactis Bl-04 4-alpha-glucanotransferase YP_002968970.1 1847833 D 580050 CDS YP_002968971.1 241191577 8009501 complement(1850503..1851105) 1 NC_012814.1 hypothetical protein 1851105 8009501 Balac_1568 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968971.1 1850503 R 580050 CDS YP_002968972.1 241191578 8009502 complement(1851424..1852260) 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; MalG-type ABC sugar transport system permease 1852260 8009502 Balac_1569 Bifidobacterium animalis subsp. lactis Bl-04 MalG-type ABC sugar transport system permease YP_002968972.1 1851424 R 580050 CDS YP_002968973.1 241191579 8009503 complement(1852260..1853114) 1 NC_012814.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 1853114 8009503 Balac_1570 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter permease YP_002968973.1 1852260 R 580050 CDS YP_002968974.1 241191580 8009504 1853577..1854587 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type response repressor 1854587 8009504 Balac_1571 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type response repressor YP_002968974.1 1853577 D 580050 CDS YP_002968975.1 241191581 8009505 complement(1854939..1856273) 1 NC_012814.1 COG1653 ABC-type sugar transport system, periplasmic component; ABC transporter substrate-binding protein 1856273 8009505 Balac_1572 Bifidobacterium animalis subsp. lactis Bl-04 ABC transporter substrate-binding protein YP_002968975.1 1854939 R 580050 CDS YP_002968976.1 241191582 8009506 1856632..1858407 1 NC_012814.1 COG0366 Glycosidases; alpha-1,4-glucosidase 1858407 8009506 Balac_1573 Bifidobacterium animalis subsp. lactis Bl-04 alpha-1,4-glucosidase YP_002968976.1 1856632 D 580050 CDS YP_002968977.1 241191583 8009507 complement(1858737..1859405) 1 NC_012814.1 COG0406 Fructose-2,6-bisphosphatase; Broad specificity phosphatase 1859405 8009507 Balac_1574 Bifidobacterium animalis subsp. lactis Bl-04 Broad specificity phosphatase YP_002968977.1 1858737 R 580050 CDS YP_002968978.1 241191584 8009508 1859568..1859984 1 NC_012814.1 hypothetical protein 1859984 8009508 Balac_1575 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968978.1 1859568 D 580050 CDS YP_002968979.1 241191585 8009509 1860084..1860860 1 NC_012814.1 COG0778 Nitroreductase; NADPH-flavin oxidoreductase 1860860 8009509 Balac_1576 Bifidobacterium animalis subsp. lactis Bl-04 NADPH-flavin oxidoreductase YP_002968979.1 1860084 D 580050 CDS YP_002968980.1 241191586 8009510 complement(1861186..1861437) 1 NC_012814.1 hypothetical protein 1861437 8009510 Balac_1577 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968980.1 1861186 R 580050 CDS YP_002968981.1 241191587 8009511 complement(1861483..1862073) 1 NC_012814.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1862073 8009511 Balac_1578 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968981.1 1861483 R 580050 CDS YP_002968982.1 241191588 8009617 1868346..1868882 1 NC_012814.1 COG0388 Predicted amidohydrolase; NAD synthetase 1868882 8009617 Balac_1582 Bifidobacterium animalis subsp. lactis Bl-04 NAD synthetase YP_002968982.1 1868346 D 580050 CDS YP_002968983.1 241191589 8009513 1868917..1870251 1 NC_012814.1 COG0388 Predicted amidohydrolase; NAD+ synthetase 1870251 8009513 Balac_1583 Bifidobacterium animalis subsp. lactis Bl-04 NAD+ synthetase YP_002968983.1 1868917 D 580050 CDS YP_002968984.1 241191590 8009514 complement(1870415..1870684) 1 NC_012814.1 COG3077 DNA-damage-inducible protein J; hypothetical protein 1870684 8009514 Balac_1584 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968984.1 1870415 R 580050 CDS YP_002968985.1 241191591 8009620 complement(1877042..1878487) 1 NC_012814.1 COG2211 Na+/melibiose symporter and related transporters; Na+/xyloside symporter related transporter 1878487 8009620 Balac_1588 Bifidobacterium animalis subsp. lactis Bl-04 Na+/xyloside symporter related transporter YP_002968985.1 1877042 R 580050 CDS YP_002968986.1 241191592 8009516 complement(1878676..1880691) 1 NC_012814.1 COG3533 Uncharacterized protein conserved in bacteria; hypothetical protein 1880691 8009516 Balac_1589 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968986.1 1878676 R 580050 CDS YP_002968987.1 241191593 8009517 1880826..1881875 1 NC_012814.1 COG1609 Transcriptional regulators; LacI-type transcriptional regulator 1881875 8009517 Balac_1590 Bifidobacterium animalis subsp. lactis Bl-04 LacI-type transcriptional regulator YP_002968987.1 1880826 D 580050 CDS YP_002968988.1 241191594 8009518 1881946..1882701 1 NC_012814.1 COG0846 NAD-dependent protein deacetylases, SIR2family; NAD-dependent protein deacetylase 1882701 8009518 Balac_1591 Bifidobacterium animalis subsp. lactis Bl-04 NAD-dependent protein deacetylase YP_002968988.1 1881946 D 580050 CDS YP_002968989.1 241191595 8009519 complement(1882859..1884097) 1 NC_012814.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 1884097 8009519 Balac_1592 Bifidobacterium animalis subsp. lactis Bl-04 threonine dehydratase YP_002968989.1 1882859 R 580050 CDS YP_002968990.1 241191596 8009520 complement(1884284..1886119) 1 NC_012814.1 COG0366 Glycosidases; oligo-1,6-glucosidase 1886119 8009520 Balac_1593 Bifidobacterium animalis subsp. lactis Bl-04 oligo-1,6-glucosidase YP_002968990.1 1884284 R 580050 CDS YP_002968991.1 241191597 8009521 complement(1886198..1886326) 1 NC_012814.1 hypothetical protein 1886326 8009521 Balac_1594 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968991.1 1886198 R 580050 CDS YP_002968992.1 241191598 8009522 1886920..1887876 1 NC_012814.1 hypothetical protein 1887876 8009522 Balac_1595 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002968992.1 1886920 D 580050 CDS YP_002968993.1 241191599 8009523 complement(1888317..1889927) 1 NC_012814.1 COG3345 Alpha-galactosidase; alpha-galactosidase 1889927 8009523 Balac_1596 Bifidobacterium animalis subsp. lactis Bl-04 alpha-galactosidase YP_002968993.1 1888317 R 580050 CDS YP_002968994.1 241191600 8009524 complement(1891162..1892067) 1 NC_012814.1 COG0395 ABC-type sugar transport system, permease component; MalG-type ABC sugar transport system permease 1892067 8009524 Balac_1597 Bifidobacterium animalis subsp. lactis Bl-04 MalG-type ABC sugar transport system permease YP_002968994.1 1891162 R 580050 CDS YP_002968995.1 241191601 8009525 complement(1892072..1893064) 1 NC_012814.1 COG1175 ABC-type sugar transport systems, permease components; MalF-type ABC sugar transport systems permease 1893064 8009525 Balac_1598 Bifidobacterium animalis subsp. lactis Bl-04 MalF-type ABC sugar transport systems permease YP_002968995.1 1892072 R 580050 CDS YP_002968996.1 241191602 8009526 complement(1893098..1894411) 1 NC_012814.1 COG1653 ABC-type sugar transport system, periplasmic component; sugar binding protein of ABC transporter system 1894411 8009526 Balac_1599 Bifidobacterium animalis subsp. lactis Bl-04 sugar binding protein of ABC transporter system YP_002968996.1 1893098 R 580050 CDS YP_002968997.1 241191603 8009527 1894542..1895750 1 NC_012814.1 COG1940 Transcriptional regulator/sugar kinase; NagC-type transcriptional regulator 1895750 8009527 Balac_1600 Bifidobacterium animalis subsp. lactis Bl-04 NagC-type transcriptional regulator YP_002968997.1 1894542 D 580050 CDS YP_002968998.1 241191604 8009528 complement(1895775..1897997) 1 NC_012814.1 COG3345 Alpha-galactosidase; alpha-galactosidase 1897997 8009528 Balac_1601 Bifidobacterium animalis subsp. lactis Bl-04 alpha-galactosidase YP_002968998.1 1895775 R 580050 CDS YP_002968999.1 241191605 8009529 complement(1898113..1898622) 1 NC_012814.1 COG0590 Cytosine/adenosine deaminases; Cytosine/adenosine deaminase 1898622 8009529 Balac_1602 Bifidobacterium animalis subsp. lactis Bl-04 Cytosine/adenosine deaminase YP_002968999.1 1898113 R 580050 CDS YP_002969000.1 241191606 8009530 1898772..1900844 1 NC_012814.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; NhaP-type Na(+)/H(+) exchanger 1900844 8009530 Balac_1603 Bifidobacterium animalis subsp. lactis Bl-04 NhaP-type Na(+)/H(+) exchanger YP_002969000.1 1898772 D 580050 CDS YP_002969001.1 241191607 8009531 complement(1900915..1901853) 1 NC_012814.1 COG0400 Predicted esterase; phospholipase/carboxylesterase 1901853 8009531 Balac_1604 Bifidobacterium animalis subsp. lactis Bl-04 phospholipase/carboxylesterase YP_002969001.1 1900915 R 580050 CDS YP_002969002.1 241191608 8009532 complement(1901896..1903455) 1 NC_012814.1 hypothetical protein 1903455 8009532 Balac_1605 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969002.1 1901896 R 580050 CDS YP_002969003.1 241191609 8009533 complement(1903505..1904086) 1 NC_012814.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1904086 dcd 8009533 dcd Bifidobacterium animalis subsp. lactis Bl-04 deoxycytidine triphosphate deaminase YP_002969003.1 1903505 R 580050 CDS YP_002969004.1 241191610 8009534 complement(1904296..1907286) 1 NC_012814.1 COG0474 Cation transport ATPase; cation-transporting ATPase PacL 1907286 8009534 Balac_1607 Bifidobacterium animalis subsp. lactis Bl-04 cation-transporting ATPase PacL YP_002969004.1 1904296 R 580050 CDS YP_002969005.1 241191611 8009535 1907601..1908596 1 NC_012814.1 COG0566 rRNA methylases; tRNA/rRNA methyltransferase protein 1908596 8009535 Balac_1608 Bifidobacterium animalis subsp. lactis Bl-04 tRNA/rRNA methyltransferase protein YP_002969005.1 1907601 D 580050 CDS YP_002969006.1 241191612 8009536 complement(1908745..1910193) 1 NC_012814.1 COG0515 Serine/threonine protein kinase; hypothetical protein 1910193 8009536 Balac_1609 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969006.1 1908745 R 580050 CDS YP_002969007.1 241191613 8009537 complement(1910401..1911534) 1 NC_012814.1 COG3839 ABC-type sugar transport systems, ATPase components; sugar ABC transporter ATP binding protein 1911534 8009537 Balac_1610 Bifidobacterium animalis subsp. lactis Bl-04 sugar ABC transporter ATP binding protein YP_002969007.1 1910401 R 580050 CDS YP_002969008.1 241191614 8009538 1911958..1912980 1 NC_012814.1 COG1226 Kef-type K+ transport systems, predictedNAD-binding component; Kef-type K+ transport systems NAD-binding protein 1912980 8009538 Balac_1611 Bifidobacterium animalis subsp. lactis Bl-04 Kef-type K+ transport systems NAD-binding protein YP_002969008.1 1911958 D 580050 CDS YP_002969009.1 241191615 8009539 1913050..1915167 1 NC_012814.1 COG0515 Serine/threonine protein kinase; hypothetical protein 1915167 8009539 Balac_1612 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969009.1 1913050 D 580050 CDS YP_002969010.1 241191616 8009540 1915547..1916584 1 NC_012814.1 COG1651 Protein-disulfide isomerase; hypothetical protein 1916584 8009540 Balac_1613 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969010.1 1915547 D 580050 CDS YP_002969011.1 241191617 8009621 1917252..1918799 1 NC_012814.1 COG3583 Uncharacterized protein conserved in bacteria; hypothetical protein 1918799 8009621 Balac_1615 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969011.1 1917252 D 580050 CDS YP_002969012.1 241191618 8009542 1918941..1919834 1 NC_012814.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1919834 ksgA 8009542 ksgA Bifidobacterium animalis subsp. lactis Bl-04 dimethyladenosine transferase YP_002969012.1 1918941 D 580050 CDS YP_002969013.1 241191619 8009543 1919831..1920787 1 NC_012814.1 COG0030 Dimethyladenosine transferase (rRNAmethylation); dimethyladenosine transferase 1920787 8009543 Balac_1617 Bifidobacterium animalis subsp. lactis Bl-04 dimethyladenosine transferase YP_002969013.1 1919831 D 580050 CDS YP_002969014.1 241191620 8009544 1920859..1921485 1 NC_012814.1 hypothetical protein 1921485 8009544 Balac_1618 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969014.1 1920859 D 580050 CDS YP_002969015.1 241191621 8009545 complement(1921615..1923123) 1 NC_012814.1 COG0617 tRNA nucleotidyltransferase/poly(Apolymerase); RNA nucleotidyltransferase 1923123 8009545 Balac_1619 Bifidobacterium animalis subsp. lactis Bl-04 RNA nucleotidyltransferase YP_002969015.1 1921615 R 580050 CDS YP_002969016.1 241191622 8009546 1923219..1924223 1 NC_012814.1 COG0494 NTP pyrophosphohydrolases includingoxidative damage repair enzymes; hypothetical protein 1924223 8009546 Balac_1620 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969016.1 1923219 D 580050 CDS YP_002969017.1 241191623 8009547 1924226..1926475 1 NC_012814.1 hypothetical protein 1926475 8009547 Balac_1621 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969017.1 1924226 D 580050 CDS YP_002969018.1 241191624 8009548 1926472..1930494 1 NC_012814.1 COG0728 Uncharacterized membrane protein, putativevirulence factor; hypothetical protein 1930494 8009548 Balac_1622 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969018.1 1926472 D 580050 CDS YP_002969019.1 241191625 8009549 1930735..1931697 1 NC_012814.1 COG0492 Thioredoxin reductase; thioredoxin reductase 1931697 8009549 Balac_1623 Bifidobacterium animalis subsp. lactis Bl-04 thioredoxin reductase YP_002969019.1 1930735 D 580050 CDS YP_002969020.1 241191626 8009550 complement(1931807..1933195) 1 NC_012814.1 COG1475 Predicted transcriptional regulators; chromosome partitioning protein 1933195 8009550 Balac_1624 Bifidobacterium animalis subsp. lactis Bl-04 chromosome partitioning protein YP_002969020.1 1931807 R 580050 CDS YP_002969021.1 241191627 8009551 complement(1933195..1934169) 1 NC_012814.1 COG1192 ATPases involved in chromosomepartitioning; ATPase for chromosome partitioning 1934169 8009551 Balac_1625 Bifidobacterium animalis subsp. lactis Bl-04 ATPase for chromosome partitioning YP_002969021.1 1933195 R 580050 CDS YP_002969022.1 241191628 8009552 complement(1934803..1935546) 1 NC_012814.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1935546 gidB 8009552 gidB Bifidobacterium animalis subsp. lactis Bl-04 16S rRNA methyltransferase GidB YP_002969022.1 1934803 R 580050 CDS YP_002969023.1 241191629 8009553 complement(1936002..1936544) 1 NC_012814.1 COG1847 Predicted RNA-binding protein; hypothetical protein 1936544 8009553 Balac_1627 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969023.1 1936002 R 580050 CDS YP_002969024.1 241191630 8009554 complement(1936667..1937677) 1 NC_012814.1 COG0706 Preprotein translocase subunit YidC; Preprotein translocase subunit 1937677 8009554 Balac_1628 Bifidobacterium animalis subsp. lactis Bl-04 Preprotein translocase subunit YP_002969024.1 1936667 R 580050 CDS YP_002969025.1 241191631 8009555 complement(1937678..1937971) 1 NC_012814.1 COG0759 Uncharacterized conserved protein; hypothetical protein 1937971 8009555 Balac_1629 Bifidobacterium animalis subsp. lactis Bl-04 hypothetical protein YP_002969025.1 1937678 R 580050 CDS YP_002969026.1 241191632 8009556 complement(1937992..1938348) 1 NC_012814.1 COG0594 RNase P protein component; ribonuclease P protein component 1938348 8009556 Balac_1630 Bifidobacterium animalis subsp. lactis Bl-04 ribonuclease P protein component YP_002969026.1 1937992 R 580050 CDS YP_002969027.1 241191633 8009557 complement(1938361..1938495) 1 NC_012814.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1938495 rpmH 8009557 rpmH Bifidobacterium animalis subsp. lactis Bl-04 50S ribosomal protein L34 YP_002969027.1 1938361 R 580050 CDS