-- dump date 20140619_002139 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 555970000001 SEQ_END SEQ_END NC_012815.1 1938483 1938483 DR NC_012815.1; contig end 1938483..1938483 Bifidobacterium animalis subsp. lactis DSM 10140 YP_002969028.1 CDS dnaA NC_012815.1 134 1885 D COG0593 ATPase involved in DNA replicationinitiation; ATPase for DNA replication initiation 134..1885 Bifidobacterium animalis subsp. lactis DSM 10140 8011252 YP_002969029.1 CDS Balat_0002 NC_012815.1 2489 3613 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2489..3613 Bifidobacterium animalis subsp. lactis DSM 10140 8009624 YP_002969030.1 CDS Balat_0003 NC_012815.1 3659 5086 D COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein RecF 3659..5086 Bifidobacterium animalis subsp. lactis DSM 10140 8009625 YP_002969031.1 CDS Balat_0004 NC_012815.1 5083 5586 D COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; hypothetical protein 5083..5586 Bifidobacterium animalis subsp. lactis DSM 10140 8009626 YP_002969032.1 CDS gyrB NC_012815.1 5777 7894 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 5777..7894 Bifidobacterium animalis subsp. lactis DSM 10140 8009627 YP_002969033.1 CDS Balat_0006 NC_012815.1 7963 10725 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 7963..10725 Bifidobacterium animalis subsp. lactis DSM 10140 8009628 YP_002969034.1 CDS Balat_0007 NC_012815.1 10851 11387 D hypothetical protein 10851..11387 Bifidobacterium animalis subsp. lactis DSM 10140 8009629 YP_002969035.1 CDS Balat_0008 NC_012815.1 11591 12664 D COG4767 Glycopeptide antibiotics resistance protein; hypothetical protein 11591..12664 Bifidobacterium animalis subsp. lactis DSM 10140 8009630 YP_002969036.1 CDS Balat_0009 NC_012815.1 12745 13539 R COG1272 Predicted membrane protein, hemolysin III homolog; putative hemolysin III-like membrane protein complement(12745..13539) Bifidobacterium animalis subsp. lactis DSM 10140 8009631 YP_002969037.1 CDS Balat_0010 NC_012815.1 14018 15364 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(14018..15364) Bifidobacterium animalis subsp. lactis DSM 10140 8009632 YP_002969038.1 CDS Balat_0011 NC_012815.1 15477 16799 R COG0477 Permeases of the major facilitator superfamily; multidrug transport protein complement(15477..16799) Bifidobacterium animalis subsp. lactis DSM 10140 8009633 YP_002969039.1 CDS Balat_0012 NC_012815.1 16847 16990 D hypothetical protein 16847..16990 Bifidobacterium animalis subsp. lactis DSM 10140 8009634 YP_002969040.1 CDS Balat_0013 NC_012815.1 16983 18170 D mannan endo-1,4-beta-mannosidase 16983..18170 Bifidobacterium animalis subsp. lactis DSM 10140 8009635 YP_002969041.1 CDS Balat_0014 NC_012815.1 18418 18918 D COG1970 Large-conductance mechanosensitive channel; large-conductance mechanosensitive channel 18418..18918 Bifidobacterium animalis subsp. lactis DSM 10140 8009636 YP_002969042.1 CDS Balat_0015 NC_012815.1 19174 19449 D COG2308 Uncharacterized conserved protein; hypothetical protein 19174..19449 Bifidobacterium animalis subsp. lactis DSM 10140 8009637 YP_002969043.1 CDS Balat_0018 NC_012815.1 19968 20732 D COG1451 Predicted metal-dependent hydrolase; hypothetical protein 19968..20732 Bifidobacterium animalis subsp. lactis DSM 10140 8009640 YP_002969044.1 CDS Balat_0019 NC_012815.1 20757 21182 R membrane-anchored glycerophosphoryl diesterphosphodiesterase-like protein complement(20757..21182) Bifidobacterium animalis subsp. lactis DSM 10140 8009641 YP_002969045.1 CDS Balat_0020 NC_012815.1 21820 22608 R COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; putative transcriptional regulator complement(21820..22608) Bifidobacterium animalis subsp. lactis DSM 10140 8009642 YP_002969046.1 CDS Balat_0021 NC_012815.1 22644 22898 D hypothetical protein 22644..22898 Bifidobacterium animalis subsp. lactis DSM 10140 8009643 YP_002969047.1 CDS Balat_0022 NC_012815.1 23538 26039 D COG0178 Excinuclease ATPase subunit; ABC transporter 23538..26039 Bifidobacterium animalis subsp. lactis DSM 10140 8009644 YP_002969048.1 CDS Balat_0023 NC_012815.1 26398 27153 D COG0500 SAM-dependent methyltransferases; methyltransferase 26398..27153 Bifidobacterium animalis subsp. lactis DSM 10140 8009645 YP_002969049.1 CDS Balat_0024 NC_012815.1 27202 28116 D hypothetical protein 27202..28116 Bifidobacterium animalis subsp. lactis DSM 10140 8009646 YP_002969050.1 CDS Balat_0025 NC_012815.1 28439 29038 D COG0431 Predicted flavoprotein; oxidoreductase 28439..29038 Bifidobacterium animalis subsp. lactis DSM 10140 8009647 YP_002969051.1 CDS Balat_0026 NC_012815.1 29241 29954 D hypothetical protein 29241..29954 Bifidobacterium animalis subsp. lactis DSM 10140 8009648 YP_002969052.1 CDS Balat_0027 NC_012815.1 30678 30914 D COG1198 Primosomal protein N (replication factor Y - superfamily II helicase); hypothetical protein 30678..30914 Bifidobacterium animalis subsp. lactis DSM 10140 8009649 YP_002969053.1 CDS Balat_0028 NC_012815.1 31096 31371 D hypothetical protein 31096..31371 Bifidobacterium animalis subsp. lactis DSM 10140 8009650 YP_002969054.1 CDS Balat_0029 NC_012815.1 31555 31824 D hypothetical protein 31555..31824 Bifidobacterium animalis subsp. lactis DSM 10140 8009651 YP_002969055.1 CDS Balat_0030 NC_012815.1 31962 32285 R COG1694 Predicted pyrophosphatase; MazG nucleotide pyrophosphohydrolase domain-containing protein complement(31962..32285) Bifidobacterium animalis subsp. lactis DSM 10140 8009652 YP_002969056.1 CDS Balat_0031 NC_012815.1 32313 32663 D hypothetical protein 32313..32663 Bifidobacterium animalis subsp. lactis DSM 10140 8009653 YP_002969057.1 CDS Balat_0032 NC_012815.1 32673 33755 D hypothetical protein 32673..33755 Bifidobacterium animalis subsp. lactis DSM 10140 8009654 YP_002969058.1 CDS Balat_0033 NC_012815.1 33890 34099 D hypothetical protein 33890..34099 Bifidobacterium animalis subsp. lactis DSM 10140 8009655 YP_002969059.1 CDS Balat_0034 NC_012815.1 34600 35961 D COG0270 Site-specific DNA methylase; site-specific DNA-methyltransferase 34600..35961 Bifidobacterium animalis subsp. lactis DSM 10140 8009656 YP_002969060.1 CDS Balat_0035 NC_012815.1 36056 36901 R hypothetical protein complement(36056..36901) Bifidobacterium animalis subsp. lactis DSM 10140 8009657 YP_002969061.1 CDS Balat_0036 NC_012815.1 37469 39892 D hypothetical protein 37469..39892 Bifidobacterium animalis subsp. lactis DSM 10140 8009658 YP_002969062.1 CDS Balat_0037 NC_012815.1 39920 40501 R hypothetical protein complement(39920..40501) Bifidobacterium animalis subsp. lactis DSM 10140 8009659 YP_002969063.1 CDS Balat_0038 NC_012815.1 41262 42617 R hypothetical protein complement(41262..42617) Bifidobacterium animalis subsp. lactis DSM 10140 8009660 YP_002969064.1 CDS Balat_0039 NC_012815.1 42959 43327 D hypothetical protein 42959..43327 Bifidobacterium animalis subsp. lactis DSM 10140 8009661 YP_002969065.1 CDS Balat_0040 NC_012815.1 43526 43639 D hypothetical protein 43526..43639 Bifidobacterium animalis subsp. lactis DSM 10140 8009662 YP_002969066.1 CDS Balat_0041 NC_012815.1 44261 44464 D hypothetical protein 44261..44464 Bifidobacterium animalis subsp. lactis DSM 10140 8009663 YP_002969067.1 CDS Balat_0042 NC_012815.1 44728 44958 R COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein complement(44728..44958) Bifidobacterium animalis subsp. lactis DSM 10140 8009664 YP_002969068.1 CDS Balat_0043 NC_012815.1 45029 45178 R hypothetical protein complement(45029..45178) Bifidobacterium animalis subsp. lactis DSM 10140 8009665 YP_002969069.1 CDS Balat_0044 NC_012815.1 45214 45474 D COG2336 Growth regulator; hypothetical protein 45214..45474 Bifidobacterium animalis subsp. lactis DSM 10140 8009666 YP_002969070.1 CDS Balat_0045 NC_012815.1 45476 45859 D COG2337 Growth inhibitor; transcriptional modulator of MazE/toxin, MazF 45476..45859 Bifidobacterium animalis subsp. lactis DSM 10140 8009667 YP_002969071.1 CDS Balat_0046 NC_012815.1 46047 46937 R COG0583 Transcriptional regulator; transcriptional regulator complement(46047..46937) Bifidobacterium animalis subsp. lactis DSM 10140 8009668 YP_002969072.1 CDS Balat_0047 NC_012815.1 47066 47329 D COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 47066..47329 Bifidobacterium animalis subsp. lactis DSM 10140 8009669 YP_002969073.1 CDS Balat_0048 NC_012815.1 47292 47942 D COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 47292..47942 Bifidobacterium animalis subsp. lactis DSM 10140 8009670 YP_002969074.1 CDS Balat_0049 NC_012815.1 48034 50283 R COG1472 Beta-glucosidase-related glycosidases; putative beta-glucosidase complement(48034..50283) Bifidobacterium animalis subsp. lactis DSM 10140 8009671 YP_002969075.1 CDS Balat_0050 NC_012815.1 51542 51979 D hypothetical protein 51542..51979 Bifidobacterium animalis subsp. lactis DSM 10140 8009672 YP_002969076.1 CDS Balat_0051 NC_012815.1 52309 53442 R COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein complement(52309..53442) Bifidobacterium animalis subsp. lactis DSM 10140 8009673 YP_002969077.1 CDS Balat_0052 NC_012815.1 53714 55240 D COG5520 O-Glycosyl hydrolase; glycoside hydrolase family protein 53714..55240 Bifidobacterium animalis subsp. lactis DSM 10140 8009674 YP_002969078.1 CDS Balat_0053 NC_012815.1 55366 57471 R COG1874 Beta-galactosidase; beta-galactosidase I complement(55366..57471) Bifidobacterium animalis subsp. lactis DSM 10140 8009675 YP_002969079.1 CDS Balat_0054 NC_012815.1 57881 59035 D COG0477 Permeases of the major facilitator superfamily; glycoside-pentoside-hexuronide:cation symporter family protein 57881..59035 Bifidobacterium animalis subsp. lactis DSM 10140 8009676 YP_002969080.1 CDS Balat_0055 NC_012815.1 59090 59731 R COG1309 Transcriptional regulator; TetR family transcriptional regulator complement(59090..59731) Bifidobacterium animalis subsp. lactis DSM 10140 8009677 YP_002969081.1 CDS Balat_0056 NC_012815.1 59884 60366 R COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA-binding ferritin-like protein complement(59884..60366) Bifidobacterium animalis subsp. lactis DSM 10140 8009678 YP_002969082.1 CDS Balat_0057 NC_012815.1 60491 61846 R COG1253 Hemolysins and related proteins containing CBS domains; hemolysin-like protein complement(60491..61846) Bifidobacterium animalis subsp. lactis DSM 10140 8009679 YP_002969083.1 CDS Balat_0058 NC_012815.1 62130 62759 R COG0288 Carbonic anhydrase; carbonic anhydrase complement(62130..62759) Bifidobacterium animalis subsp. lactis DSM 10140 8009680 YP_002969084.1 CDS Balat_0059 NC_012815.1 62901 64016 D COG1609 Transcriptional regulators; LacI-type transcriptional regulator 62901..64016 Bifidobacterium animalis subsp. lactis DSM 10140 8009681 YP_002969085.1 CDS Balat_0060 NC_012815.1 64069 64296 R hypothetical protein complement(64069..64296) Bifidobacterium animalis subsp. lactis DSM 10140 8009682 YP_002969086.1 CDS Balat_0061 NC_012815.1 64454 64624 R COG4214 ABC-type xylose transport system, permease component; ABC-type xylose transport system permease complement(64454..64624) Bifidobacterium animalis subsp. lactis DSM 10140 8009683 YP_002969087.1 CDS Balat_0062 NC_012815.1 64619 65323 D COG1129 ABC-type sugar transport system, ATPase component; pentose ABC transporter ATP binding protein 64619..65323 Bifidobacterium animalis subsp. lactis DSM 10140 8009684 YP_002969088.1 CDS Balat_0063 NC_012815.1 65524 65865 D hypothetical protein 65524..65865 Bifidobacterium animalis subsp. lactis DSM 10140 8009685 YP_002969089.1 CDS Balat_0064 NC_012815.1 65860 66894 R COG1609 Transcriptional regulators; RbsR-type transcription regulator/ ribose operon repressor complement(65860..66894) Bifidobacterium animalis subsp. lactis DSM 10140 8009686 YP_002969090.1 CDS Balat_0065 NC_012815.1 67012 68553 R COG3534 Alpha-L-arabinofuranosidase; alpha-L-arabinofuranosidase complement(67012..68553) Bifidobacterium animalis subsp. lactis DSM 10140 8009687 YP_002969091.1 CDS Balat_0066 NC_012815.1 68830 70491 D COG1070 Sugar (pentulose and hexulose kinases); sugar kinase 68830..70491 Bifidobacterium animalis subsp. lactis DSM 10140 8009688 YP_002969092.1 CDS Balat_0067 NC_012815.1 70547 71239 D catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 70547..71239 Bifidobacterium animalis subsp. lactis DSM 10140 8009689 YP_002969093.1 CDS Balat_0068 NC_012815.1 71503 73020 D catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 71503..73020 Bifidobacterium animalis subsp. lactis DSM 10140 8009690 YP_002969094.1 CDS Balat_0069 NC_012815.1 73155 74018 D COG0656 Aldo/keto reductases, related to diketogulonate reductase; dehydrogenase or reductase protein 73155..74018 Bifidobacterium animalis subsp. lactis DSM 10140 8009691 YP_002969095.1 CDS Balat_0070 NC_012815.1 74259 77015 R COG2352 Phosphoenolpyruvate carboxylase; hypothetical protein complement(74259..77015) Bifidobacterium animalis subsp. lactis DSM 10140 8009692 YP_002969096.1 CDS Balat_0071 NC_012815.1 77254 79002 D COG2966 Uncharacterized conserved protein; hypothetical protein 77254..79002 Bifidobacterium animalis subsp. lactis DSM 10140 8009693 YP_002969097.1 CDS Balat_0072 NC_012815.1 79093 80226 R COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein complement(79093..80226) Bifidobacterium animalis subsp. lactis DSM 10140 8009694 YP_002969098.1 CDS Balat_0073 NC_012815.1 80579 81682 R COG0180 Tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase complement(80579..81682) Bifidobacterium animalis subsp. lactis DSM 10140 8009695 YP_002969099.1 CDS Balat_0074 NC_012815.1 81843 82190 D hypothetical protein 81843..82190 Bifidobacterium animalis subsp. lactis DSM 10140 8009696 YP_002969100.1 CDS Balat_0075 NC_012815.1 82389 82772 R hypothetical protein complement(82389..82772) Bifidobacterium animalis subsp. lactis DSM 10140 8009697 YP_002969101.1 CDS Balat_0076 NC_012815.1 83374 85830 D COG0058 Glucan phosphorylase; glycogen phosphorylase 83374..85830 Bifidobacterium animalis subsp. lactis DSM 10140 8009698 YP_002969102.1 CDS Balat_0077 NC_012815.1 86071 86298 R hypothetical protein complement(86071..86298) Bifidobacterium animalis subsp. lactis DSM 10140 8009699 YP_002969103.1 CDS Balat_0078 NC_012815.1 86641 87342 D COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); rhomboid family membrane protein 86641..87342 Bifidobacterium animalis subsp. lactis DSM 10140 8009700 YP_002969104.1 CDS Balat_0079 NC_012815.1 88340 89746 D COG0500 SAM-dependent methyltransferases; N6-adenine-specific methylase 88340..89746 Bifidobacterium animalis subsp. lactis DSM 10140 8009701 YP_002969105.1 CDS Balat_0080 NC_012815.1 90000 90575 R integral membrane protein involved in inhibition of the Z-ring formation; putative septation inhibitor protein complement(90000..90575) Bifidobacterium animalis subsp. lactis DSM 10140 8009702 YP_002969106.1 CDS Balat_0081 NC_012815.1 90682 91479 D COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 90682..91479 Bifidobacterium animalis subsp. lactis DSM 10140 8009703 YP_002969107.1 CDS Balat_0082 NC_012815.1 91567 92721 D COG3764 Sortase (surface protein transpeptidase); hypothetical protein 91567..92721 Bifidobacterium animalis subsp. lactis DSM 10140 8009704 YP_002969108.1 CDS Balat_0083 NC_012815.1 92962 93609 D COG0512 Anthranilate/para-aminobenzoate synthases component II; Para-aminobenzoate synthase glutamineamidotransferase component II 92962..93609 Bifidobacterium animalis subsp. lactis DSM 10140 8009705 YP_002969109.1 CDS Balat_0084 NC_012815.1 93919 96051 R COG0515 Serine/threonine protein kinase; serine-threonine protein kinase complement(93919..96051) Bifidobacterium animalis subsp. lactis DSM 10140 8009706 YP_002969110.1 CDS Balat_0085 NC_012815.1 96044 97069 R COG0515 Serine/threonine protein kinase; serine-threonine protein kinase complement(96044..97069) Bifidobacterium animalis subsp. lactis DSM 10140 8009707 YP_002969111.1 CDS Balat_0086 NC_012815.1 97066 98532 R COG0768 Cell division proteinFtsI/penicillin-binding protein 2; penicillin binding protein transpeptidase complement(97066..98532) Bifidobacterium animalis subsp. lactis DSM 10140 8009708 YP_002969112.1 CDS Balat_0087 NC_012815.1 98525 100267 R COG0772 Bacterial cell division membrane protein; cell division membrane protein complement(98525..100267) Bifidobacterium animalis subsp. lactis DSM 10140 8009709 YP_002969113.1 CDS Balat_0088 NC_012815.1 100270 101808 R COG0631 Serine/threonine protein phosphatase; phosphoprotein phosphatase complement(100270..101808) Bifidobacterium animalis subsp. lactis DSM 10140 8009710 YP_002969114.1 CDS Balat_0089 NC_012815.1 101830 102375 R COG1716 FOG: FHA domain; hypothetical protein complement(101830..102375) Bifidobacterium animalis subsp. lactis DSM 10140 8009711 YP_002969115.1 CDS Balat_0090 NC_012815.1 102394 103095 R COG1716 FOG: FHA domain; hypothetical protein complement(102394..103095) Bifidobacterium animalis subsp. lactis DSM 10140 8009712 YP_002969116.1 CDS Balat_0091 NC_012815.1 103860 106274 D COG1506 Dipeptidylaminopeptidases/acylaminoacyl-peptidases; Dipeptidylaminopeptidase/acylaminoacyl- peptidase 103860..106274 Bifidobacterium animalis subsp. lactis DSM 10140 8009713 YP_002969117.1 CDS Balat_0092 NC_012815.1 106313 107365 R COG0697 Permeases of the drug/metabolite transporter (DMT superfamily); putative permease complement(106313..107365) Bifidobacterium animalis subsp. lactis DSM 10140 8009714 YP_002969118.1 CDS Balat_0093 NC_012815.1 107450 108535 R COG2267 Lysophospholipase; hypothetical protein complement(107450..108535) Bifidobacterium animalis subsp. lactis DSM 10140 8009715 YP_002969119.1 CDS Balat_0094 NC_012815.1 108714 109052 D hypothetical protein 108714..109052 Bifidobacterium animalis subsp. lactis DSM 10140 8009716 YP_002969120.1 CDS Balat_0095 NC_012815.1 109132 110085 D COG0500 SAM-dependent methyltransferases; methyltransferase 109132..110085 Bifidobacterium animalis subsp. lactis DSM 10140 8009717 YP_002969121.1 CDS Balat_0096 NC_012815.1 110587 110841 R COG2261 Predicted membrane protein; hypothetical protein complement(110587..110841) Bifidobacterium animalis subsp. lactis DSM 10140 8009718 YP_002969122.1 CDS Balat_0097 NC_012815.1 111113 111370 R COG2261 Predicted membrane protein; hypothetical protein complement(111113..111370) Bifidobacterium animalis subsp. lactis DSM 10140 8009719 YP_002969123.1 CDS Balat_0099 NC_012815.1 112141 113589 R COG0493 NADPH-dependent glutamate synthase betachain and related oxidoreductases; ferredoxin/ferredoxin-NADP reductase complement(112141..113589) Bifidobacterium animalis subsp. lactis DSM 10140 8009721 YP_002969124.1 CDS Balat_0100 NC_012815.1 113779 116013 R COG2217 Cation transport ATPase; cation-transporting ATPase V complement(113779..116013) Bifidobacterium animalis subsp. lactis DSM 10140 8009722 YP_002969125.1 CDS Balat_0101 NC_012815.1 116322 118163 R COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; DO serine protease complement(116322..118163) Bifidobacterium animalis subsp. lactis DSM 10140 8009723 YP_002969126.1 CDS Balat_0102 NC_012815.1 118338 118952 D COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase 118338..118952 Bifidobacterium animalis subsp. lactis DSM 10140 8009724 YP_002969127.1 CDS Balat_0103 NC_012815.1 119450 120979 D COG0790 FOG: TPR repeat, SEL1 subfamily; hypothetical protein 119450..120979 Bifidobacterium animalis subsp. lactis DSM 10140 8009725 YP_002969128.1 CDS Balat_0104 NC_012815.1 121079 122416 D COG0343 Queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 121079..122416 Bifidobacterium animalis subsp. lactis DSM 10140 8009726 YP_002969129.1 CDS Balat_0106 NC_012815.1 122644 123615 R putative metalloprotease; heat shock protein HtpX complement(122644..123615) Bifidobacterium animalis subsp. lactis DSM 10140 8009728 YP_002969130.1 CDS Balat_0107 NC_012815.1 123665 124825 R hypothetical protein complement(123665..124825) Bifidobacterium animalis subsp. lactis DSM 10140 8009729 YP_002969131.1 CDS Balat_0108 NC_012815.1 124983 125624 D COG2135 Uncharacterized conserved protein; hypothetical protein 124983..125624 Bifidobacterium animalis subsp. lactis DSM 10140 8009730 YP_002969132.1 CDS Balat_0109 NC_012815.1 125727 126971 D COG2814 Arabinose efflux permease; AraJ-like protein 125727..126971 Bifidobacterium animalis subsp. lactis DSM 10140 8009731 YP_002969133.1 CDS Balat_0110 NC_012815.1 127054 127317 R hypothetical protein complement(127054..127317) Bifidobacterium animalis subsp. lactis DSM 10140 8009732 YP_002969134.1 CDS Balat_0111 NC_012815.1 127630 127935 R COG3077 DNA-damage-inducible protein J; hypothetical protein complement(127630..127935) Bifidobacterium animalis subsp. lactis DSM 10140 8009733 YP_002969135.1 CDS Balat_0112 NC_012815.1 127988 128467 R COG0350 Methylated DNA-protein cysteinemethyltransferase; methylated-DNA--protein- cysteinemethyltransferase complement(127988..128467) Bifidobacterium animalis subsp. lactis DSM 10140 8009734 YP_002969136.1 CDS Balat_0113 NC_012815.1 128864 130081 D oxidoreductase 128864..130081 Bifidobacterium animalis subsp. lactis DSM 10140 8009735 YP_002969137.1 CDS Balat_0114 NC_012815.1 130041 130808 R COG0599 Uncharacterized homolog ofgamma-carboxymuconolactone decarboxylase subunit; putative carboxymuconolactone decarboxylase complement(130041..130808) Bifidobacterium animalis subsp. lactis DSM 10140 8009736 YP_002969138.1 CDS Balat_0115 NC_012815.1 130832 131275 R COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; carboxymuconolactone decarboxylase complement(130832..131275) Bifidobacterium animalis subsp. lactis DSM 10140 8009737 YP_002969139.1 CDS Balat_0116 NC_012815.1 131417 132403 R COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein complement(131417..132403) Bifidobacterium animalis subsp. lactis DSM 10140 8009738 YP_002969140.1 CDS Balat_0117 NC_012815.1 132538 133407 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 132538..133407 Bifidobacterium animalis subsp. lactis DSM 10140 8009739 YP_002969141.1 CDS Balat_0118 NC_012815.1 133448 134473 R COG0667 Predicted oxidoreductases (related toaryl-alcohol dehydrogenases); Tas protein complement(133448..134473) Bifidobacterium animalis subsp. lactis DSM 10140 8009740 YP_002969142.1 CDS Balat_0119 NC_012815.1 134530 134712 R hypothetical protein complement(134530..134712) Bifidobacterium animalis subsp. lactis DSM 10140 8009741 YP_002969143.1 CDS Balat_0120 NC_012815.1 134766 136061 R COG4097 Predicted ferric reductase; ferric reductase complement(134766..136061) Bifidobacterium animalis subsp. lactis DSM 10140 8009742 YP_002969144.1 CDS Balat_0121 NC_012815.1 136098 136754 R COG0716 Flavodoxins; hypothetical protein complement(136098..136754) Bifidobacterium animalis subsp. lactis DSM 10140 8009743 YP_002969145.1 CDS Balat_0122 NC_012815.1 136744 137493 D COG0789 Predicted transcriptional regulators; transcriptional regulator 136744..137493 Bifidobacterium animalis subsp. lactis DSM 10140 8009744 YP_002969146.1 CDS Balat_0123 NC_012815.1 137546 138019 R COG0716 Flavodoxins; flavodoxin complement(137546..138019) Bifidobacterium animalis subsp. lactis DSM 10140 8009745 YP_002969147.1 CDS Balat_0124 NC_012815.1 138087 138875 R COG0702 Predicted nucleoside-diphosphate-sugare pimerases; NAD-dependent epimerase/dehydratase complement(138087..138875) Bifidobacterium animalis subsp. lactis DSM 10140 8009746 YP_002969148.1 CDS Balat_0125 NC_012815.1 138893 139951 R COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase complement(138893..139951) Bifidobacterium animalis subsp. lactis DSM 10140 8009747 YP_002969149.1 CDS Balat_0126 NC_012815.1 140142 141041 D COG0583 Transcriptional regulator; LysR family transcriptional regulator 140142..141041 Bifidobacterium animalis subsp. lactis DSM 10140 8009748 YP_002969150.1 CDS Balat_0127 NC_012815.1 141044 142354 R COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase complement(141044..142354) Bifidobacterium animalis subsp. lactis DSM 10140 8009749 YP_002969151.1 CDS Balat_0128 NC_012815.1 142498 143562 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 142498..143562 Bifidobacterium animalis subsp. lactis DSM 10140 8009750 YP_002969152.1 CDS Balat_0129 NC_012815.1 144115 145401 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 144115..145401 Bifidobacterium animalis subsp. lactis DSM 10140 8009751 YP_002969153.1 CDS Balat_0130 NC_012815.1 145542 146474 D COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 145542..146474 Bifidobacterium animalis subsp. lactis DSM 10140 8009752 YP_002969154.1 CDS Balat_0131 NC_012815.1 146474 146848 D COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 146474..146848 Bifidobacterium animalis subsp. lactis DSM 10140 8009753 YP_002969155.1 CDS Balat_0132 NC_012815.1 147437 148873 D COG0559 Branched-chain amino acid ABC-typetransport system, permease components; branched-chain amino acid ABC-type transport system permease 147437..148873 Bifidobacterium animalis subsp. lactis DSM 10140 8009754 YP_002969156.1 CDS Balat_0133 NC_012815.1 148877 149860 D COG4177 ABC-type branched-chain amino acid transport system, permease component; branched-chain amino acid transport system permease 148877..149860 Bifidobacterium animalis subsp. lactis DSM 10140 8009755 YP_002969157.1 CDS Balat_0134 NC_012815.1 149853 150860 D COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid transport systemATP-binding protein 149853..150860 Bifidobacterium animalis subsp. lactis DSM 10140 8009756 YP_002969158.1 CDS Balat_0135 NC_012815.1 150853 151668 D COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 150853..151668 Bifidobacterium animalis subsp. lactis DSM 10140 8009757 YP_002969159.1 CDS Balat_0136 NC_012815.1 151811 153076 D COG0683 ABC-type branched-chain amino acidtransport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein 151811..153076 Bifidobacterium animalis subsp. lactis DSM 10140 8009758 YP_002969160.1 CDS Balat_0137 NC_012815.1 153154 154182 R COG1609 Transcriptional regulators; LacI-type transcriptional regulator complement(153154..154182) Bifidobacterium animalis subsp. lactis DSM 10140 8009759 YP_002969161.1 CDS Balat_0138 NC_012815.1 154489 156009 D COG0366 Glycosidases; sucrose phosphorylase 154489..156009 Bifidobacterium animalis subsp. lactis DSM 10140 8009760 YP_002969162.1 CDS Balat_0139 NC_012815.1 156066 157679 D COG0477 Permeases of the major facilitator superfamily; membrane protein with transport function 156066..157679 Bifidobacterium animalis subsp. lactis DSM 10140 8009761 YP_002969163.1 CDS Balat_0140 NC_012815.1 157945 158664 D COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein 157945..158664 Bifidobacterium animalis subsp. lactis DSM 10140 8009762 YP_002969164.1 CDS Balat_0141 NC_012815.1 158700 159944 D COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; biotin carboxylase/biotin carboxyl carrier protein 158700..159944 Bifidobacterium animalis subsp. lactis DSM 10140 8009763 YP_002969165.1 CDS Balat_0142 NC_012815.1 160348 161307 D hypothetical protein 160348..161307 Bifidobacterium animalis subsp. lactis DSM 10140 8009764 YP_002969166.1 CDS Balat_0143 NC_012815.1 161413 163002 D COG2211 Na+/melibiose symporter and related transporters; Na+/sugar symporter 161413..163002 Bifidobacterium animalis subsp. lactis DSM 10140 8009765 YP_002969167.1 CDS Balat_0144 NC_012815.1 163022 163528 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase complement(163022..163528) Bifidobacterium animalis subsp. lactis DSM 10140 8009766 YP_002969168.1 CDS Balat_0145 NC_012815.1 163525 163809 R COG4453 Uncharacterized protein conserved in bacteria; hypothetical protein complement(163525..163809) Bifidobacterium animalis subsp. lactis DSM 10140 8009767 YP_002969169.1 CDS Balat_0146 NC_012815.1 163939 164067 D hypothetical protein 163939..164067 Bifidobacterium animalis subsp. lactis DSM 10140 8009768 YP_002969170.1 CDS Balat_0147 NC_012815.1 164818 166209 D COG0477 Permeases of the major facilitator superfamily; transmembrane transport protein 164818..166209 Bifidobacterium animalis subsp. lactis DSM 10140 8009769 YP_002969171.1 CDS Balat_0148 NC_012815.1 166620 167672 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 166620..167672 Bifidobacterium animalis subsp. lactis DSM 10140 8009770 YP_002969172.1 CDS Balat_0149 NC_012815.1 168307 170004 R sialic acid-specific 9-O-acetylesterase complement(168307..170004) Bifidobacterium animalis subsp. lactis DSM 10140 8009771 YP_002969173.1 CDS Balat_0150 NC_012815.1 170428 171525 R RnfABCDGE type electron transport complex subunit D complement(170428..171525) Bifidobacterium animalis subsp. lactis DSM 10140 8009772 YP_002969174.1 CDS Balat_0151 NC_012815.1 172049 173431 D COG2723Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase; putative beta-glucosidase 172049..173431 Bifidobacterium animalis subsp. lactis DSM 10140 8009773 YP_002969175.1 CDS Balat_0152 NC_012815.1 173861 174598 D beta-mannosidase 173861..174598 Bifidobacterium animalis subsp. lactis DSM 10140 8009774 YP_002969176.1 CDS Balat_0153 NC_012815.1 174855 175883 D COG1609 Transcriptional regulators; LacI family transcription regulator 174855..175883 Bifidobacterium animalis subsp. lactis DSM 10140 8009775 YP_002969177.1 CDS Balat_0154 NC_012815.1 176167 176802 R hypothetical protein complement(176167..176802) Bifidobacterium animalis subsp. lactis DSM 10140 8009776 YP_002969178.1 CDS Balat_0155 NC_012815.1 176886 177617 R hypothetical protein complement(176886..177617) Bifidobacterium animalis subsp. lactis DSM 10140 8009777 YP_002969179.1 CDS Balat_0156 NC_012815.1 177916 178077 D hypothetical protein 177916..178077 Bifidobacterium animalis subsp. lactis DSM 10140 8009778 YP_002969180.1 CDS Balat_0157 NC_012815.1 178391 179656 D COG2942 N-acyl-D-glucosamine 2-epimerase; hypothetical protein 178391..179656 Bifidobacterium animalis subsp. lactis DSM 10140 8009779 YP_002969181.1 CDS Balat_0158 NC_012815.1 180184 180924 D COG4619 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATP-binding protein 180184..180924 Bifidobacterium animalis subsp. lactis DSM 10140 8009780 YP_002969182.1 CDS Balat_0159 NC_012815.1 180926 181792 D COG0390 ABC-type uncharacterized transport system, permease component; hypothetical protein 180926..181792 Bifidobacterium animalis subsp. lactis DSM 10140 8009781 YP_002969183.1 CDS Balat_0160 NC_012815.1 181945 183441 D COG1113 Gamma-aminobutyrate permease and related permeases; aromatic amino acid transport protein AroP 181945..183441 Bifidobacterium animalis subsp. lactis DSM 10140 8009782 YP_002969184.1 CDS Balat_0161 NC_012815.1 184023 184724 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 184023..184724 Bifidobacterium animalis subsp. lactis DSM 10140 8009783 YP_002969185.1 CDS Balat_0162 NC_012815.1 184735 187689 D COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 184735..187689 Bifidobacterium animalis subsp. lactis DSM 10140 8009784 YP_002969186.1 CDS Balat_0163 NC_012815.1 187744 189288 D COG1113 Gamma-aminobutyrate permease and related permeases; amino acid permease 187744..189288 Bifidobacterium animalis subsp. lactis DSM 10140 8009785 YP_002969187.1 CDS Balat_0164 NC_012815.1 189300 189545 R COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein complement(189300..189545) Bifidobacterium animalis subsp. lactis DSM 10140 8009786 YP_002969188.1 CDS Balat_0165 NC_012815.1 189542 189979 R putative ABC transporter integral membrane protein complement(189542..189979) Bifidobacterium animalis subsp. lactis DSM 10140 8009787 YP_002969189.1 CDS Balat_0166 NC_012815.1 189897 191618 R COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein complement(189897..191618) Bifidobacterium animalis subsp. lactis DSM 10140 8009788 YP_002969190.1 CDS Balat_0167 NC_012815.1 191615 192037 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein complement(191615..192037) Bifidobacterium animalis subsp. lactis DSM 10140 8009789 YP_002969191.1 CDS Balat_0168 NC_012815.1 192732 193325 D COG1846 Transcriptional regulators; MarR family transcriptional regulator 192732..193325 Bifidobacterium animalis subsp. lactis DSM 10140 8009790 YP_002969192.1 CDS Balat_0169 NC_012815.1 193397 195316 D COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 193397..195316 Bifidobacterium animalis subsp. lactis DSM 10140 8009791 YP_002969193.1 CDS Balat_0170 NC_012815.1 195388 197223 D COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease 195388..197223 Bifidobacterium animalis subsp. lactis DSM 10140 8009792 YP_002969194.1 CDS Balat_0171 NC_012815.1 197237 198763 R COG0726 Predicted xylanase/chitin deacetylase; putative secreted polysaccharide deacetylase complement(197237..198763) Bifidobacterium animalis subsp. lactis DSM 10140 8009793 YP_002969195.1 CDS Balat_0172 NC_012815.1 199138 199827 R COG0671 Membrane-associated phospholipidphosphatase; phosphoesterase PA-phosphatase-like protein complement(199138..199827) Bifidobacterium animalis subsp. lactis DSM 10140 8009794 YP_002969196.1 CDS Balat_0173 NC_012815.1 199903 200538 D COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase 199903..200538 Bifidobacterium animalis subsp. lactis DSM 10140 8009795 YP_002969197.1 CDS Balat_0174 NC_012815.1 200629 201048 D hypothetical protein 200629..201048 Bifidobacterium animalis subsp. lactis DSM 10140 8009796 YP_002969198.1 CDS Balat_0175 NC_012815.1 202039 203298 R COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid transport system substrate-binding protein complement(202039..203298) Bifidobacterium animalis subsp. lactis DSM 10140 8009797 YP_002969199.1 CDS Balat_0176 NC_012815.1 203889 204542 R COG1309 Transcriptional regulator; TetR family transcriptional regulator complement(203889..204542) Bifidobacterium animalis subsp. lactis DSM 10140 8009798 YP_002969200.1 CDS Balat_0177 NC_012815.1 204552 206750 R COG1511 Predicted membrane protein; putative phage infection protein complement(204552..206750) Bifidobacterium animalis subsp. lactis DSM 10140 8009799 YP_002969201.1 CDS Balat_0178 NC_012815.1 206747 209515 R COG1511 Predicted membrane protein; putative phage infection protein complement(206747..209515) Bifidobacterium animalis subsp. lactis DSM 10140 8009800 YP_002969202.1 CDS Balat_0179 NC_012815.1 209809 210450 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 209809..210450 Bifidobacterium animalis subsp. lactis DSM 10140 8009801 YP_002969203.1 CDS Balat_0180 NC_012815.1 210447 211187 D COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease 210447..211187 Bifidobacterium animalis subsp. lactis DSM 10140 8009802 YP_002969204.1 CDS Balat_0181 NC_012815.1 211240 212727 D COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 211240..212727 Bifidobacterium animalis subsp. lactis DSM 10140 8009803 YP_002969205.1 CDS Balat_0182 NC_012815.1 212777 214360 R COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; hypothetical protein complement(212777..214360) Bifidobacterium animalis subsp. lactis DSM 10140 8009804 YP_002969206.1 CDS Balat_0183 NC_012815.1 214556 215437 R COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; hypothetical protein complement(214556..215437) Bifidobacterium animalis subsp. lactis DSM 10140 8009805 YP_002969207.1 CDS Balat_0184 NC_012815.1 215573 216340 D COG1309 Transcriptional regulator; hypothetical protein 215573..216340 Bifidobacterium animalis subsp. lactis DSM 10140 8009806 YP_002969208.1 CDS Balat_0185 NC_012815.1 216520 217230 R hypothetical protein complement(216520..217230) Bifidobacterium animalis subsp. lactis DSM 10140 8009807 YP_002969209.1 CDS Balat_0187 NC_012815.1 217561 219129 D COG4690 Dipeptidase; dipeptidase 217561..219129 Bifidobacterium animalis subsp. lactis DSM 10140 8009809 YP_002969210.1 CDS Balat_0188 NC_012815.1 219315 220028 R COG1309 Transcriptional regulator; TetR family transcriptional regulator complement(219315..220028) Bifidobacterium animalis subsp. lactis DSM 10140 8009810 YP_002969211.1 CDS Balat_0189 NC_012815.1 220155 221555 D COG0552 Signal recognition particle GTPase; FtsY signal recognition particle 220155..221555 Bifidobacterium animalis subsp. lactis DSM 10140 8009811 YP_002969212.1 CDS Balat_0190 NC_012815.1 221815 223110 D COG0004 Ammonia permease; ammonium transporter 221815..223110 Bifidobacterium animalis subsp. lactis DSM 10140 8009812 YP_002969213.1 CDS Balat_0191 NC_012815.1 223112 223450 D COG0347 Nitrogen regulatory protein PII; nitrogen regulatory protein N-II 223112..223450 Bifidobacterium animalis subsp. lactis DSM 10140 8009813 YP_002969214.1 CDS Balat_0192 NC_012815.1 223761 225587 D COG2844 UTP:GlnB (protein PII uridylyl transferase); protein-PII uridylyltransferase 223761..225587 Bifidobacterium animalis subsp. lactis DSM 10140 8009814 YP_002969215.1 CDS Balat_0193 NC_012815.1 225948 226220 D COG1476 Predicted transcriptional regulators; putative transcriptional regulator 225948..226220 Bifidobacterium animalis subsp. lactis DSM 10140 8009815 YP_002969216.1 CDS Balat_0194 NC_012815.1 226279 227658 D COG0305 Replicative DNA helicase; replicative DNA helicase 226279..227658 Bifidobacterium animalis subsp. lactis DSM 10140 8009816 YP_002969217.1 CDS Balat_0195 NC_012815.1 227755 229263 D COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 227755..229263 Bifidobacterium animalis subsp. lactis DSM 10140 8009817 YP_002969218.1 CDS Balat_0196 NC_012815.1 229332 230081 D COG3442 Predicted glutamine amidotransferase; cobyric acid synthase CobQ 229332..230081 Bifidobacterium animalis subsp. lactis DSM 10140 8009818 YP_002969219.1 CDS Balat_0197 NC_012815.1 230189 230536 D COG3937 Uncharacterized conserved protein; hypothetical protein 230189..230536 Bifidobacterium animalis subsp. lactis DSM 10140 8009819 YP_002969220.1 CDS Balat_0198 NC_012815.1 230645 232795 D COG0661 Predicted unusual protein kinase; Unusual protein kinase 230645..232795 Bifidobacterium animalis subsp. lactis DSM 10140 8009820 YP_002969221.1 CDS Balat_0199 NC_012815.1 232906 233943 D COG0584 Glycerophosphoryl diesterphosphodiesterase; phosphodiesterase 232906..233943 Bifidobacterium animalis subsp. lactis DSM 10140 8009821 YP_002969222.1 CDS upp NC_012815.1 234039 234680 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(234039..234680) Bifidobacterium animalis subsp. lactis DSM 10140 8009822 YP_002969223.1 CDS Balat_0201 NC_012815.1 235106 235831 R hypothetical protein complement(235106..235831) Bifidobacterium animalis subsp. lactis DSM 10140 8009823 YP_002969224.1 CDS Balat_0202 NC_012815.1 235836 236879 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; MutT1 protein complement(235836..236879) Bifidobacterium animalis subsp. lactis DSM 10140 8009824 YP_002969225.1 CDS Balat_0203 NC_012815.1 237016 239250 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(237016..239250) Bifidobacterium animalis subsp. lactis DSM 10140 8009825 YP_002969226.1 CDS Balat_0204 NC_012815.1 240138 241151 D hypothetical protein 240138..241151 Bifidobacterium animalis subsp. lactis DSM 10140 8009826 YP_002969227.1 CDS Balat_0205 NC_012815.1 241148 242356 D COG4962 Flp pilus assembly protein, ATPase CpaF; Flp pilus assembly protein ABC transporter ATPase 241148..242356 Bifidobacterium animalis subsp. lactis DSM 10140 8009827 YP_002969228.1 CDS Balat_0206 NC_012815.1 242362 243096 D COG4965 Flp pilus assembly protein TadB; Flp pilus assembly protein 242362..243096 Bifidobacterium animalis subsp. lactis DSM 10140 8009828 YP_002969229.1 CDS Balat_0207 NC_012815.1 243194 243730 D Flp pilus assembly protein 243194..243730 Bifidobacterium animalis subsp. lactis DSM 10140 8009829 YP_002969230.1 CDS Balat_0208 NC_012815.1 243907 244182 D hypothetical protein 243907..244182 Bifidobacterium animalis subsp. lactis DSM 10140 8009830 YP_002969231.1 CDS Balat_0209 NC_012815.1 244187 244570 D hypothetical protein 244187..244570 Bifidobacterium animalis subsp. lactis DSM 10140 8009831 YP_002969232.1 CDS Balat_0210 NC_012815.1 244617 245057 D hypothetical protein 244617..245057 Bifidobacterium animalis subsp. lactis DSM 10140 8009832 YP_002969233.1 CDS Balat_0211 NC_012815.1 245206 247758 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 245206..247758 Bifidobacterium animalis subsp. lactis DSM 10140 8009833 YP_002969234.1 CDS recR NC_012815.1 247789 248391 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 247789..248391 Bifidobacterium animalis subsp. lactis DSM 10140 8009834 YP_002969235.1 CDS Balat_0213 NC_012815.1 248512 249276 D COG0527 Aspartokinases; aspartokinase 248512..249276 Bifidobacterium animalis subsp. lactis DSM 10140 8009835 YP_002969236.1 CDS Balat_0214 NC_012815.1 249349 249915 D COG0527 Aspartokinases; aspartokinase 249349..249915 Bifidobacterium animalis subsp. lactis DSM 10140 8009836 YP_002969237.1 CDS Balat_0215 NC_012815.1 249972 251042 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 249972..251042 Bifidobacterium animalis subsp. lactis DSM 10140 8009837 YP_002969238.1 CDS Balat_0216 NC_012815.1 251227 251850 D hypothetical protein 251227..251850 Bifidobacterium animalis subsp. lactis DSM 10140 8009838 YP_002969239.1 CDS Balat_0217 NC_012815.1 252415 254328 D COG0119 Isopropylmalate/homocitrate/citramalatesynthases; 2-isopropylmalate synthase 252415..254328 Bifidobacterium animalis subsp. lactis DSM 10140 8009839 YP_002969240.1 CDS Balat_0218 NC_012815.1 254476 256884 R COG0744 Membrane carboxypeptidase (penicillin-binding protein); penicillin-binding protein complement(254476..256884) Bifidobacterium animalis subsp. lactis DSM 10140 8009840 YP_002969241.1 CDS Balat_0219 NC_012815.1 257186 258328 D COG1260 Myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase 257186..258328 Bifidobacterium animalis subsp. lactis DSM 10140 8009841 YP_002969242.1 CDS Balat_0220 NC_012815.1 258723 259943 D pre-pilin peptidase 258723..259943 Bifidobacterium animalis subsp. lactis DSM 10140 8009842 YP_002969243.1 CDS Balat_0221 NC_012815.1 260288 263248 D COG0550 Topoisomerase IA; DNA topoisomerase I 260288..263248 Bifidobacterium animalis subsp. lactis DSM 10140 8009843 YP_002969244.1 CDS Balat_0222 NC_012815.1 263932 264552 D COG0125 Thymidylate kinase; Thymidylate kinase 263932..264552 Bifidobacterium animalis subsp. lactis DSM 10140 8009844 YP_002969245.1 CDS Balat_0223 NC_012815.1 264558 265850 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 264558..265850 Bifidobacterium animalis subsp. lactis DSM 10140 8009845 YP_002969246.1 CDS Balat_0224 NC_012815.1 265873 266577 D COG1881 Phospholipid-binding protein; hypothetical protein 265873..266577 Bifidobacterium animalis subsp. lactis DSM 10140 8009846 YP_002969247.1 CDS Balat_0225 NC_012815.1 267250 268863 D COG4690 Dipeptidase; Dipeptidase 267250..268863 Bifidobacterium animalis subsp. lactis DSM 10140 8009847 YP_002969248.1 CDS Balat_0226 NC_012815.1 269383 271008 D COG4690 Dipeptidase; dipeptidase 269383..271008 Bifidobacterium animalis subsp. lactis DSM 10140 8009848 YP_002969249.1 CDS Balat_0227 NC_012815.1 271359 272528 D COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 271359..272528 Bifidobacterium animalis subsp. lactis DSM 10140 8009849 YP_002969250.1 CDS Balat_0228 NC_012815.1 272635 274152 D COG2759 Formyltetrahydrofolate synthetase; formate-tetrahydrofolate ligase 272635..274152 Bifidobacterium animalis subsp. lactis DSM 10140 8009850 YP_002969251.1 CDS Balat_0229 NC_012815.1 274267 274614 R COG1049 Aconitase B; hypothetical protein complement(274267..274614) Bifidobacterium animalis subsp. lactis DSM 10140 8009851 YP_002969252.1 CDS Balat_0230 NC_012815.1 275239 276225 D hypothetical protein 275239..276225 Bifidobacterium animalis subsp. lactis DSM 10140 8009852 YP_002969253.1 CDS Balat_0231 NC_012815.1 276243 276800 R COG2246 Predicted membrane protein; hypothetical protein complement(276243..276800) Bifidobacterium animalis subsp. lactis DSM 10140 8009853 YP_002969254.1 CDS Balat_0232 NC_012815.1 277026 277970 R hypothetical protein complement(277026..277970) Bifidobacterium animalis subsp. lactis DSM 10140 8009854 YP_002969255.1 CDS Balat_0233 NC_012815.1 278503 279162 R COG0406 Fructose-2,6-bisphosphatase; hypothetical protein complement(278503..279162) Bifidobacterium animalis subsp. lactis DSM 10140 8009855 YP_002969256.1 CDS Balat_0234 NC_012815.1 279569 280987 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 279569..280987 Bifidobacterium animalis subsp. lactis DSM 10140 8009856 YP_002969257.1 CDS Balat_0235 NC_012815.1 281394 282527 R COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein complement(281394..282527) Bifidobacterium animalis subsp. lactis DSM 10140 8009857 YP_002969258.1 CDS gltX NC_012815.1 282864 284381 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 282864..284381 Bifidobacterium animalis subsp. lactis DSM 10140 8009858 YP_002969259.1 CDS Balat_0239 NC_012815.1 285048 286304 D COG1409 Predicted phosphohydrolases; hypothetical protein 285048..286304 Bifidobacterium animalis subsp. lactis DSM 10140 8009861 YP_002969260.1 CDS Balat_0240 NC_012815.1 287070 287888 R COG1414 Transcriptional regulator; IclR family transcriptional regulator complement(287070..287888) Bifidobacterium animalis subsp. lactis DSM 10140 8009862 YP_002969261.1 CDS Balat_0241 NC_012815.1 288190 289587 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 288190..289587 Bifidobacterium animalis subsp. lactis DSM 10140 8009863 YP_002969262.1 CDS leuD NC_012815.1 289625 290305 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 289625..290305 Bifidobacterium animalis subsp. lactis DSM 10140 8009864 YP_002969263.1 CDS Balat_0243 NC_012815.1 290560 290838 D COG1522 Transcriptional regulators; AsnC family transcriptional regulator 290560..290838 Bifidobacterium animalis subsp. lactis DSM 10140 8009865 YP_002969264.1 CDS Balat_0244 NC_012815.1 291750 293096 R COG0446 Uncharacterized NAD (FAD-dependent dehydrogenases); NADH oxidase complement(291750..293096) Bifidobacterium animalis subsp. lactis DSM 10140 8009866 YP_002969265.1 CDS Balat_0245 NC_012815.1 293350 294678 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 293350..294678 Bifidobacterium animalis subsp. lactis DSM 10140 8009867 YP_002969266.1 CDS Balat_0246 NC_012815.1 295176 296165 D COG0204 1-acyl-sn-glycerol-3-phosphateacyltransferase; hypothetical protein 295176..296165 Bifidobacterium animalis subsp. lactis DSM 10140 8009868 YP_002969267.1 CDS gpsA NC_012815.1 296521 297519 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 296521..297519 Bifidobacterium animalis subsp. lactis DSM 10140 8009869 YP_002969268.1 CDS ddl NC_012815.1 297881 299017 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 297881..299017 Bifidobacterium animalis subsp. lactis DSM 10140 8009870 YP_002969269.1 CDS Balat_0249 NC_012815.1 299283 300419 D hypothetical protein 299283..300419 Bifidobacterium animalis subsp. lactis DSM 10140 8009871 YP_002969270.1 CDS Balat_0250 NC_012815.1 300655 301770 D COG1266 Predicted metal-dependent membrane protease; hypothetical protein 300655..301770 Bifidobacterium animalis subsp. lactis DSM 10140 8009872 YP_002969271.1 CDS Balat_0251 NC_012815.1 301754 302569 R COG0668 Small-conductance mechanosensitive channel; hypothetical protein complement(301754..302569) Bifidobacterium animalis subsp. lactis DSM 10140 8009873 YP_002969272.1 CDS Balat_0252 NC_012815.1 302626 303195 R COG1309 Transcriptional regulator; AcrR family transcriptional regulator complement(302626..303195) Bifidobacterium animalis subsp. lactis DSM 10140 8009874 YP_002969273.1 CDS Balat_0253 NC_012815.1 303417 304613 R hypothetical protein complement(303417..304613) Bifidobacterium animalis subsp. lactis DSM 10140 8009875 YP_002969274.1 CDS Balat_0254 NC_012815.1 304728 305594 D COG4905 Predicted membrane protein; hypothetical protein 304728..305594 Bifidobacterium animalis subsp. lactis DSM 10140 8009876 YP_002969275.1 CDS Balat_0255 NC_012815.1 305658 306854 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 305658..306854 Bifidobacterium animalis subsp. lactis DSM 10140 8009877 YP_002969276.1 CDS Balat_0256 NC_012815.1 307109 309967 R hypothetical protein complement(307109..309967) Bifidobacterium animalis subsp. lactis DSM 10140 8009878 YP_002969277.1 CDS Balat_0257 NC_012815.1 310345 311997 D COG0457 FOG: TPR repeat; hypothetical protein 310345..311997 Bifidobacterium animalis subsp. lactis DSM 10140 8009879 YP_002969278.1 CDS Balat_0258 NC_012815.1 312004 313059 R COG0524 Sugar kinases, ribokinase family; Ribokinase family sugar kinase complement(312004..313059) Bifidobacterium animalis subsp. lactis DSM 10140 8009880 YP_002969279.1 CDS rpmB NC_012815.1 313341 313520 D required for 70S ribosome assembly; 50S ribosomal protein L28 313341..313520 Bifidobacterium animalis subsp. lactis DSM 10140 8009881 YP_002969280.1 CDS Balat_0260 NC_012815.1 313761 316133 D COG1200 RecG-like helicase; RecG-like helicase 313761..316133 Bifidobacterium animalis subsp. lactis DSM 10140 8009882 YP_002969281.1 CDS fbp NC_012815.1 316615 324705 D hypothetical protein 316615..324705 Bifidobacterium animalis subsp. lactis DSM 10140 8009883 YP_002969282.1 CDS Balat_0262 NC_012815.1 324932 325057 D hypothetical protein 324932..325057 Bifidobacterium animalis subsp. lactis DSM 10140 8009884 YP_002969283.1 CDS Balat_0263 NC_012815.1 325354 325929 D COG0742 N6-adenine-specific methylase; hypothetical protein 325354..325929 Bifidobacterium animalis subsp. lactis DSM 10140 8009885 YP_002969284.1 CDS trmD NC_012815.1 325956 326783 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(325956..326783) Bifidobacterium animalis subsp. lactis DSM 10140 8009886 YP_002969285.1 CDS Balat_0265 NC_012815.1 326939 327598 R COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM complement(326939..327598) Bifidobacterium animalis subsp. lactis DSM 10140 8009887 YP_002969286.1 CDS Balat_0266 NC_012815.1 327595 327828 R COG1837 Predicted RNA-binding protein (contains KH domain); hypothetical protein complement(327595..327828) Bifidobacterium animalis subsp. lactis DSM 10140 8009888 YP_002969287.1 CDS rpsP NC_012815.1 327833 328303 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(327833..328303) Bifidobacterium animalis subsp. lactis DSM 10140 8009889 YP_002969288.1 CDS Balat_0268 NC_012815.1 328533 331991 D COG3250 Beta-galactosidase/beta-glucuronidase; beta-galactosidase 328533..331991 Bifidobacterium animalis subsp. lactis DSM 10140 8009890 YP_002969289.1 CDS Balat_0269 NC_012815.1 332271 333440 R COG3568 Metal-dependent hydrolase; hypothetical protein complement(332271..333440) Bifidobacterium animalis subsp. lactis DSM 10140 8009891 YP_002969290.1 CDS Balat_0270 NC_012815.1 333903 334901 R COG0053 Predicted Co/Zn/Cd cation transporters; putative Co/Zn/Cd cation transporter complement(333903..334901) Bifidobacterium animalis subsp. lactis DSM 10140 8009892 YP_002969291.1 CDS Balat_0271 NC_012815.1 334936 336579 D COG0541 Signal recognition particle GTPase; signal recognition particle protein 334936..336579 Bifidobacterium animalis subsp. lactis DSM 10140 8009893 YP_002969292.1 CDS cysS NC_012815.1 337723 339360 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(337723..339360) Bifidobacterium animalis subsp. lactis DSM 10140 8009894 YP_002969293.1 CDS Balat_0273 NC_012815.1 339409 341610 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase complement(339409..341610) Bifidobacterium animalis subsp. lactis DSM 10140 8009895 YP_002969294.1 CDS Balat_0274 NC_012815.1 341776 342513 R COG0518 GMP synthase - Glutamine amidotransferase domain; amidotransferase complement(341776..342513) Bifidobacterium animalis subsp. lactis DSM 10140 8009896 YP_002969295.1 CDS ilvH NC_012815.1 342690 343244 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(342690..343244) Bifidobacterium animalis subsp. lactis DSM 10140 8009897 YP_002969296.1 CDS Balat_0276 NC_012815.1 343260 345188 R acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit complement(343260..345188) Bifidobacterium animalis subsp. lactis DSM 10140 8009898 YP_002969297.1 CDS rnc NC_012815.1 345564 346340 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(345564..346340) Bifidobacterium animalis subsp. lactis DSM 10140 8009899 YP_002969298.1 CDS rpmF NC_012815.1 346665 346859 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(346665..346859) Bifidobacterium animalis subsp. lactis DSM 10140 8009900 YP_002969299.1 CDS Balat_0279 NC_012815.1 346938 347534 R COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; putative metal-binding/nucleic acid-binding protein complement(346938..347534) Bifidobacterium animalis subsp. lactis DSM 10140 8009901 YP_002969300.1 CDS Balat_0280 NC_012815.1 347619 348320 R COG3599 Cell division initiation protein; hypothetical protein complement(347619..348320) Bifidobacterium animalis subsp. lactis DSM 10140 8009902 YP_002969301.1 CDS coaD NC_012815.1 348371 348850 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(348371..348850) Bifidobacterium animalis subsp. lactis DSM 10140 8009903 YP_002969302.1 CDS Balat_0282 NC_012815.1 349026 349319 D hypothetical protein 349026..349319 Bifidobacterium animalis subsp. lactis DSM 10140 8009904 YP_002969303.1 CDS Balat_0283 NC_012815.1 349454 350461 R COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); reductase complement(349454..350461) Bifidobacterium animalis subsp. lactis DSM 10140 8009905 YP_002969304.1 CDS Balat_0284 NC_012815.1 350538 351998 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(350538..351998) Bifidobacterium animalis subsp. lactis DSM 10140 8009906 YP_002969305.1 CDS Balat_0285 NC_012815.1 352166 352786 D hypothetical protein 352166..352786 Bifidobacterium animalis subsp. lactis DSM 10140 8009907 YP_002969306.1 CDS rph NC_012815.1 353044 353736 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 353044..353736 Bifidobacterium animalis subsp. lactis DSM 10140 8009908 YP_002969307.1 CDS Balat_0287 NC_012815.1 353765 354484 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 353765..354484 Bifidobacterium animalis subsp. lactis DSM 10140 8009909 YP_002969308.1 CDS Balat_0288 NC_012815.1 354550 355809 D COG2348 Uncharacterized protein involved in methicillin resistance; FemAB-like protein 354550..355809 Bifidobacterium animalis subsp. lactis DSM 10140 8009910 YP_002969309.1 CDS Balat_0289 NC_012815.1 355839 356846 R COG0679 Predicted permeases; hypothetical protein complement(355839..356846) Bifidobacterium animalis subsp. lactis DSM 10140 8009911 YP_002969310.1 CDS Balat_0292 NC_012815.1 357298 358509 D COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanylyltransferase 357298..358509 Bifidobacterium animalis subsp. lactis DSM 10140 8009914 YP_002969311.1 CDS pgi NC_012815.1 358799 360496 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 358799..360496 Bifidobacterium animalis subsp. lactis DSM 10140 8009915 YP_002969312.1 CDS rplS NC_012815.1 360820 361185 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 360820..361185 Bifidobacterium animalis subsp. lactis DSM 10140 8009916 YP_002969313.1 CDS Balat_0295 NC_012815.1 361399 362124 D COG0681 Signal peptidase I; signal peptidase I 361399..362124 Bifidobacterium animalis subsp. lactis DSM 10140 8009917 YP_002969314.1 CDS rnhB NC_012815.1 362169 362945 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 362169..362945 Bifidobacterium animalis subsp. lactis DSM 10140 8009918 YP_002969315.1 CDS Balat_0297 NC_012815.1 363052 364038 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; SalX-type ABC antimicrobial peptide ABC transporter ATPase 363052..364038 Bifidobacterium animalis subsp. lactis DSM 10140 8009919 YP_002969316.1 CDS Balat_0298 NC_012815.1 364035 365459 D COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 364035..365459 Bifidobacterium animalis subsp. lactis DSM 10140 8009920 YP_002969317.1 CDS Balat_0299 NC_012815.1 365643 366584 R COG0679 Predicted permeases; hypothetical protein complement(365643..366584) Bifidobacterium animalis subsp. lactis DSM 10140 8009921 YP_002969318.1 CDS Balat_0300 NC_012815.1 366798 368018 D catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 366798..368018 Bifidobacterium animalis subsp. lactis DSM 10140 8009922 YP_002969319.1 CDS Balat_0301 NC_012815.1 368581 371667 D COG1530 Ribonucleases G and E; ribonuclease G 368581..371667 Bifidobacterium animalis subsp. lactis DSM 10140 8009923 YP_002969320.1 CDS rplU NC_012815.1 372655 372963 D COG0261 Ribosomal protein L21; 50S ribosomal protein L21 372655..372963 Bifidobacterium animalis subsp. lactis DSM 10140 8009924 YP_002969321.1 CDS rpmA NC_012815.1 373003 373254 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 373003..373254 Bifidobacterium animalis subsp. lactis DSM 10140 8009925 YP_002969322.1 CDS obgE NC_012815.1 373439 375151 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 373439..375151 Bifidobacterium animalis subsp. lactis DSM 10140 8009926 YP_002969323.1 CDS Balat_0305 NC_012815.1 375212 376345 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 375212..376345 Bifidobacterium animalis subsp. lactis DSM 10140 8009927 YP_002969324.1 CDS Balat_0306 NC_012815.1 376459 377676 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 376459..377676 Bifidobacterium animalis subsp. lactis DSM 10140 8009928 YP_002969325.1 CDS secE NC_012815.1 377939 378169 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 377939..378169 Bifidobacterium animalis subsp. lactis DSM 10140 8009930 YP_002969326.1 CDS Balat_0309 NC_012815.1 378300 379292 D COG0250 Transcription antiterminator; transcription antiterminator 378300..379292 Bifidobacterium animalis subsp. lactis DSM 10140 8009931 YP_002969327.1 CDS rplK NC_012815.1 379534 379965 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 379534..379965 Bifidobacterium animalis subsp. lactis DSM 10140 8009932 YP_002969328.1 CDS rplA NC_012815.1 379985 380674 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 379985..380674 Bifidobacterium animalis subsp. lactis DSM 10140 8009933 YP_002969329.1 CDS Balat_0312 NC_012815.1 380797 381588 D COG2508 Regulator of polyketide synthase expression; hypothetical protein 380797..381588 Bifidobacterium animalis subsp. lactis DSM 10140 8009934 YP_002969330.1 CDS Balat_0313 NC_012815.1 381646 382542 D COG0340 Biotin-(acetyl-CoA carboxylase ligase); hypothetical protein 381646..382542 Bifidobacterium animalis subsp. lactis DSM 10140 8009935 YP_002969331.1 CDS Balat_0314 NC_012815.1 382564 383193 R COG1268 Uncharacterized conserved protein; hypothetical protein complement(382564..383193) Bifidobacterium animalis subsp. lactis DSM 10140 8009936 YP_002969332.1 CDS Balat_0315 NC_012815.1 383489 385363 D COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; JadJ 383489..385363 Bifidobacterium animalis subsp. lactis DSM 10140 8009937 YP_002969333.1 CDS Balat_0316 NC_012815.1 385365 386996 D COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); propionyl-CoA carboxylase subunit beta 385365..386996 Bifidobacterium animalis subsp. lactis DSM 10140 8009938 YP_002969334.1 CDS Balat_0317 NC_012815.1 387130 396447 D COG0331 (acyl-carrier-proteinS-malonyltransferase); fatty acid synthase Fas 387130..396447 Bifidobacterium animalis subsp. lactis DSM 10140 8009939 YP_002969335.1 CDS Balat_0318 NC_012815.1 396680 397126 D COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); holo-ACP synthase 396680..397126 Bifidobacterium animalis subsp. lactis DSM 10140 8009940 YP_002969336.1 CDS Balat_0320 NC_012815.1 397339 398049 D hypothetical protein 397339..398049 Bifidobacterium animalis subsp. lactis DSM 10140 8009942 YP_002969337.1 CDS Balat_0321 NC_012815.1 398125 399096 R COG0039 Malate/lactate dehydrogenases; L-lactate dehydrogenase complement(398125..399096) Bifidobacterium animalis subsp. lactis DSM 10140 8009943 YP_002969338.1 CDS rpsO NC_012815.1 399404 399673 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 399404..399673 Bifidobacterium animalis subsp. lactis DSM 10140 8009944 YP_002969339.1 CDS Balat_0323 NC_012815.1 400015 402636 D COG1185 Polyribonucleotide nucleotidyltransferase(polynucleotide phosphorylase); polynucleotide phosphorylase 400015..402636 Bifidobacterium animalis subsp. lactis DSM 10140 8009945 YP_002969340.1 CDS Balat_0324 NC_012815.1 402925 403500 D COG1704 Uncharacterized conserved protein; LemA-like protein 402925..403500 Bifidobacterium animalis subsp. lactis DSM 10140 8009946 YP_002969341.1 CDS Balat_0325 NC_012815.1 403586 405802 D COG4907 Predicted membrane protein; hypothetical protein 403586..405802 Bifidobacterium animalis subsp. lactis DSM 10140 8009947 YP_002969342.1 CDS nrdF NC_012815.1 405799 406764 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(405799..406764) Bifidobacterium animalis subsp. lactis DSM 10140 8009948 YP_002969343.1 CDS Balat_0327 NC_012815.1 406804 408900 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(406804..408900) Bifidobacterium animalis subsp. lactis DSM 10140 8009949 YP_002969344.1 CDS nrdI NC_012815.1 408940 409365 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein complement(408940..409365) Bifidobacterium animalis subsp. lactis DSM 10140 8009950 YP_002969345.1 CDS Balat_0329 NC_012815.1 409362 409625 R COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein NrdH complement(409362..409625) Bifidobacterium animalis subsp. lactis DSM 10140 8009951 YP_002969346.1 CDS Balat_0330 NC_012815.1 409934 410797 D COG0667 Predicted oxidoreductases (related toaryl-alcohol dehydrogenases); aldo/keto reductase 409934..410797 Bifidobacterium animalis subsp. lactis DSM 10140 8009952 YP_002969347.1 CDS Balat_0331 NC_012815.1 411108 412643 D COG0826 Collagenase and related proteases; protease or peptidase 411108..412643 Bifidobacterium animalis subsp. lactis DSM 10140 8009953 YP_002969348.1 CDS Balat_0332 NC_012815.1 412972 414177 D COG1496 Uncharacterized conserved protein; hypothetical protein 412972..414177 Bifidobacterium animalis subsp. lactis DSM 10140 8009954 YP_002969349.1 CDS Balat_0333 NC_012815.1 414204 415031 D COG1211 4-diphosphocytidyl-2-methyl-D-erithritolsynthase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 414204..415031 Bifidobacterium animalis subsp. lactis DSM 10140 8009955 YP_002969350.1 CDS Balat_0334 NC_012815.1 414991 415710 D COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase); Pyrrolidone-carboxylate peptidase 414991..415710 Bifidobacterium animalis subsp. lactis DSM 10140 8009956 YP_002969351.1 CDS Balat_0335 NC_012815.1 415869 417587 D COG3599 Cell division initiation protein; hypothetical protein 415869..417587 Bifidobacterium animalis subsp. lactis DSM 10140 8009957 YP_002969352.1 CDS Balat_0336 NC_012815.1 417768 419108 D COG3579 Aminopeptidase C; aminopeptidase 417768..419108 Bifidobacterium animalis subsp. lactis DSM 10140 8009958 YP_002969353.1 CDS Balat_0337 NC_012815.1 419580 420710 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 419580..420710 Bifidobacterium animalis subsp. lactis DSM 10140 8009959 YP_002969354.1 CDS Balat_0338 NC_012815.1 420925 422928 D COG1835 Predicted acyltransferases; hypothetical protein 420925..422928 Bifidobacterium animalis subsp. lactis DSM 10140 8009960 YP_002969355.1 CDS Balat_0339 NC_012815.1 423001 424248 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 423001..424248 Bifidobacterium animalis subsp. lactis DSM 10140 8009961 YP_002969356.1 CDS Balat_0340 NC_012815.1 424327 425019 D COG0775 Nucleoside phosphorylase; 5'-methylthioadenosine nucleosidase 424327..425019 Bifidobacterium animalis subsp. lactis DSM 10140 8009962 YP_002969357.1 CDS Balat_0341 NC_012815.1 425051 426274 D COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 425051..426274 Bifidobacterium animalis subsp. lactis DSM 10140 8009963 YP_002969358.1 CDS Balat_0342 NC_012815.1 426271 426978 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 426271..426978 Bifidobacterium animalis subsp. lactis DSM 10140 8009964 YP_002969359.1 CDS Balat_0343 NC_012815.1 427065 428180 D COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 427065..428180 Bifidobacterium animalis subsp. lactis DSM 10140 8009965 YP_002969360.1 CDS Balat_0344 NC_012815.1 428185 429165 D COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 428185..429165 Bifidobacterium animalis subsp. lactis DSM 10140 8009966 YP_002969361.1 CDS Balat_0345 NC_012815.1 429162 430154 D COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter substrate-binding protein 429162..430154 Bifidobacterium animalis subsp. lactis DSM 10140 8009967 YP_002969362.1 CDS Balat_0346 NC_012815.1 430191 430970 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 430191..430970 Bifidobacterium animalis subsp. lactis DSM 10140 8009968 YP_002969363.1 CDS Balat_0347 NC_012815.1 431262 432602 D COG2252 Permeases; hypothetical protein 431262..432602 Bifidobacterium animalis subsp. lactis DSM 10140 8009969 YP_002969364.1 CDS Balat_0348 NC_012815.1 432937 433860 R COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein complement(432937..433860) Bifidobacterium animalis subsp. lactis DSM 10140 8009970 YP_002969365.1 CDS rplJ NC_012815.1 434213 434734 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 434213..434734 Bifidobacterium animalis subsp. lactis DSM 10140 8009971 YP_002969366.1 CDS rplL NC_012815.1 434845 435225 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 434845..435225 Bifidobacterium animalis subsp. lactis DSM 10140 8009972 YP_002969367.1 CDS Balat_0351 NC_012815.1 435508 437082 D COG1716 FOG: FHA domain; Tfp pilus assembly protein 435508..437082 Bifidobacterium animalis subsp. lactis DSM 10140 8009973 YP_002969368.1 CDS Balat_0352 NC_012815.1 437079 440726 D COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 437079..440726 Bifidobacterium animalis subsp. lactis DSM 10140 8009974 YP_002969369.1 CDS Balat_0353 NC_012815.1 440761 441003 D hypothetical protein 440761..441003 Bifidobacterium animalis subsp. lactis DSM 10140 8009975 YP_002969370.1 CDS Balat_0354 NC_012815.1 441022 441579 R hypothetical protein complement(441022..441579) Bifidobacterium animalis subsp. lactis DSM 10140 8009976 YP_002969371.1 CDS Balat_0355 NC_012815.1 441818 442009 R COG2331 Uncharacterized protein conserved in bacteria; hypothetical protein complement(441818..442009) Bifidobacterium animalis subsp. lactis DSM 10140 8009977 YP_002969372.1 CDS Balat_0356 NC_012815.1 442141 442878 R COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase complement(442141..442878) Bifidobacterium animalis subsp. lactis DSM 10140 8009978 YP_002969373.1 CDS Balat_0357 NC_012815.1 443035 443718 D COG1670 Acetyltransferases, including N-acetylasesof ribosomal proteins; acetytransferase 443035..443718 Bifidobacterium animalis subsp. lactis DSM 10140 8009979 YP_002969374.1 CDS Balat_0358 NC_012815.1 443740 444963 D hypothetical protein 443740..444963 Bifidobacterium animalis subsp. lactis DSM 10140 8009980 YP_002969375.1 CDS groES NC_012815.1 445185 445481 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 445185..445481 Bifidobacterium animalis subsp. lactis DSM 10140 8009981 YP_002969376.1 CDS rpmG NC_012815.1 446150 446320 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 446150..446320 Bifidobacterium animalis subsp. lactis DSM 10140 8009985 YP_002969377.1 CDS Balat_0364 NC_012815.1 446414 447634 D COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase 446414..447634 Bifidobacterium animalis subsp. lactis DSM 10140 8009986 YP_002969378.1 CDS Balat_0365 NC_012815.1 448006 449508 D COG0531 Amino acid transporters; Amino acid transporter 448006..449508 Bifidobacterium animalis subsp. lactis DSM 10140 8009987 YP_002969379.1 CDS Balat_0366 NC_012815.1 449674 449997 D COG1146 Ferredoxin; ferredoxin 449674..449997 Bifidobacterium animalis subsp. lactis DSM 10140 8009988 YP_002969380.1 CDS Balat_0367 NC_012815.1 450092 451249 D catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 450092..451249 Bifidobacterium animalis subsp. lactis DSM 10140 8009989 YP_002969381.1 CDS Balat_0368 NC_012815.1 451287 452603 R COG0389 Nucleotidyltransferase/DNA polymeraseinvolved in DNA repair; DNA-damage-inducible protein P complement(451287..452603) Bifidobacterium animalis subsp. lactis DSM 10140 8009990 YP_002969382.1 CDS Balat_0370 NC_012815.1 453223 454230 D COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; 2-hydroxyacid dehydrogenase 453223..454230 Bifidobacterium animalis subsp. lactis DSM 10140 8009992 YP_002969383.1 CDS Balat_0371 NC_012815.1 454287 454922 D COG1739 Uncharacterized conserved protein; hypothetical protein 454287..454922 Bifidobacterium animalis subsp. lactis DSM 10140 8009993 YP_002969384.1 CDS Balat_0372 NC_012815.1 454901 455719 D AbrB family transcriptional regulator 454901..455719 Bifidobacterium animalis subsp. lactis DSM 10140 8009994 YP_002969385.1 CDS Balat_0373 NC_012815.1 455828 457996 D COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 455828..457996 Bifidobacterium animalis subsp. lactis DSM 10140 8009995 YP_002969386.1 CDS rplM NC_012815.1 458278 458727 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 458278..458727 Bifidobacterium animalis subsp. lactis DSM 10140 8009996 YP_002969387.1 CDS rpsI NC_012815.1 458747 459238 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 458747..459238 Bifidobacterium animalis subsp. lactis DSM 10140 8009997 YP_002969388.1 CDS Balat_0376 NC_012815.1 459346 462042 R COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX complement(459346..462042) Bifidobacterium animalis subsp. lactis DSM 10140 8009998 YP_002969389.1 CDS Balat_0377 NC_012815.1 462101 463192 R COG1940 Transcriptional regulator/sugar kinase; Rok family repressor complement(462101..463192) Bifidobacterium animalis subsp. lactis DSM 10140 8009999 YP_002969390.1 CDS Balat_0378 NC_012815.1 463599 466346 D COG1012 NAD-dependent aldehyde dehydrogenases; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 463599..466346 Bifidobacterium animalis subsp. lactis DSM 10140 8010000 YP_002969391.1 CDS Balat_0379 NC_012815.1 466662 467636 R hypothetical protein complement(466662..467636) Bifidobacterium animalis subsp. lactis DSM 10140 8010001 YP_002969392.1 CDS Balat_0380 NC_012815.1 467832 468581 D hypothetical protein 467832..468581 Bifidobacterium animalis subsp. lactis DSM 10140 8010002 YP_002969393.1 CDS rpsJ NC_012815.1 468859 469167 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 468859..469167 Bifidobacterium animalis subsp. lactis DSM 10140 8010003 YP_002969394.1 CDS rplC NC_012815.1 469185 469835 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 469185..469835 Bifidobacterium animalis subsp. lactis DSM 10140 8010004 YP_002969395.1 CDS rplD NC_012815.1 469841 470497 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 469841..470497 Bifidobacterium animalis subsp. lactis DSM 10140 8010005 YP_002969396.1 CDS rplW NC_012815.1 470502 470798 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 470502..470798 Bifidobacterium animalis subsp. lactis DSM 10140 8010006 YP_002969397.1 CDS rplB NC_012815.1 470836 471666 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 470836..471666 Bifidobacterium animalis subsp. lactis DSM 10140 8010007 YP_002969398.1 CDS rpsS NC_012815.1 471682 471960 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 471682..471960 Bifidobacterium animalis subsp. lactis DSM 10140 8010008 YP_002969399.2 CDS rplV NC_012815.1 471982 472341 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 471982..472341 Bifidobacterium animalis subsp. lactis DSM 10140 8010009 YP_002969400.1 CDS rpsC NC_012815.1 472344 473177 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 472344..473177 Bifidobacterium animalis subsp. lactis DSM 10140 8010010 YP_002969401.1 CDS rplP NC_012815.1 473185 473604 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 473185..473604 Bifidobacterium animalis subsp. lactis DSM 10140 8010011 YP_002969402.1 CDS Balat_0390 NC_012815.1 473604 473852 D COG0255 Ribosomal protein L29; Ribosomal protein L29 473604..473852 Bifidobacterium animalis subsp. lactis DSM 10140 8010012 YP_002969403.1 CDS rpsQ NC_012815.1 473862 474122 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 473862..474122 Bifidobacterium animalis subsp. lactis DSM 10140 8010013 YP_002969404.1 CDS rplN NC_012815.1 474211 474579 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 474211..474579 Bifidobacterium animalis subsp. lactis DSM 10140 8010014 YP_002969405.1 CDS rplX NC_012815.1 474581 474916 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 474581..474916 Bifidobacterium animalis subsp. lactis DSM 10140 8010015 YP_002969406.1 CDS rplE NC_012815.1 474913 475497 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 474913..475497 Bifidobacterium animalis subsp. lactis DSM 10140 8010016 YP_002969407.1 CDS rpsN NC_012815.1 475499 475684 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 475499..475684 Bifidobacterium animalis subsp. lactis DSM 10140 8010017 YP_002969408.1 CDS rpsH NC_012815.1 475772 476170 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 475772..476170 Bifidobacterium animalis subsp. lactis DSM 10140 8010018 YP_002969409.1 CDS rplF NC_012815.1 476187 476726 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 476187..476726 Bifidobacterium animalis subsp. lactis DSM 10140 8010019 YP_002969410.1 CDS rplR NC_012815.1 476728 477099 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 476728..477099 Bifidobacterium animalis subsp. lactis DSM 10140 8010020 YP_002969411.1 CDS rpsE NC_012815.1 477123 477827 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 477123..477827 Bifidobacterium animalis subsp. lactis DSM 10140 8010021 YP_002969412.1 CDS rpmD NC_012815.1 477827 478009 D COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 477827..478009 Bifidobacterium animalis subsp. lactis DSM 10140 8010022 YP_002969413.1 CDS rplO NC_012815.1 478012 478470 D late assembly protein; 50S ribosomal protein L15 478012..478470 Bifidobacterium animalis subsp. lactis DSM 10140 8010023 YP_002969414.1 CDS secY NC_012815.1 478708 480057 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 478708..480057 Bifidobacterium animalis subsp. lactis DSM 10140 8010024 YP_002969415.1 CDS adk NC_012815.1 480230 480802 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 480230..480802 Bifidobacterium animalis subsp. lactis DSM 10140 8010025 YP_002969416.1 CDS infA NC_012815.1 481051 481269 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 481051..481269 Bifidobacterium animalis subsp. lactis DSM 10140 8010026 YP_002969417.1 CDS rpmJ NC_012815.1 481308 481421 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 481308..481421 Bifidobacterium animalis subsp. lactis DSM 10140 8010027 YP_002969418.1 CDS rpsM NC_012815.1 481560 481937 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 481560..481937 Bifidobacterium animalis subsp. lactis DSM 10140 8010028 YP_002969419.1 CDS Balat_0407 NC_012815.1 482014 482412 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 482014..482412 Bifidobacterium animalis subsp. lactis DSM 10140 8010029 YP_002969420.1 CDS Balat_0408 NC_012815.1 482491 483486 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 482491..483486 Bifidobacterium animalis subsp. lactis DSM 10140 8010030 YP_002969421.1 CDS rplQ NC_012815.1 483571 484017 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 483571..484017 Bifidobacterium animalis subsp. lactis DSM 10140 8010031 YP_002969422.1 CDS Balat_0410 NC_012815.1 484239 485015 D COG0101 Pseudouridylate synthase; tRNA pseudouridine synthase A 484239..485015 Bifidobacterium animalis subsp. lactis DSM 10140 8010032 YP_002969423.1 CDS Balat_0412 NC_012815.1 485394 486305 R hypothetical protein complement(485394..486305) Bifidobacterium animalis subsp. lactis DSM 10140 8010034 YP_002969424.1 CDS nusA NC_012815.1 486418 487494 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 486418..487494 Bifidobacterium animalis subsp. lactis DSM 10140 8010035 YP_002969425.1 CDS infB NC_012815.1 487704 490538 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 487704..490538 Bifidobacterium animalis subsp. lactis DSM 10140 8010036 YP_002969426.1 CDS rbfA NC_012815.1 490692 491345 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 490692..491345 Bifidobacterium animalis subsp. lactis DSM 10140 8010037 YP_002969427.1 CDS Balat_0416 NC_012815.1 491349 492401 D COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 491349..492401 Bifidobacterium animalis subsp. lactis DSM 10140 8010038 YP_002969428.1 CDS Balat_0417 NC_012815.1 492409 493695 D COG0196 FAD synthase; riboflavin kinase 492409..493695 Bifidobacterium animalis subsp. lactis DSM 10140 8010039 YP_002969429.1 CDS Balat_0418 NC_012815.1 493707 495182 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(493707..495182) Bifidobacterium animalis subsp. lactis DSM 10140 8010040 YP_002969430.1 CDS Balat_0419 NC_012815.1 495405 495986 D hypothetical protein 495405..495986 Bifidobacterium animalis subsp. lactis DSM 10140 8010041 YP_002969431.1 CDS Balat_0420 NC_012815.1 496319 497020 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(496319..497020) Bifidobacterium animalis subsp. lactis DSM 10140 8010042 YP_002969432.1 CDS Balat_0421 NC_012815.1 497110 498099 R COG0328 Ribonuclease HI; ribonuclease H complement(497110..498099) Bifidobacterium animalis subsp. lactis DSM 10140 8010043 YP_002969433.1 CDS Balat_0423 NC_012815.1 499327 500613 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(499327..500613) Bifidobacterium animalis subsp. lactis DSM 10140 8010045 YP_002969434.1 CDS Balat_0424 NC_012815.1 500785 501942 D COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; hypothetical protein 500785..501942 Bifidobacterium animalis subsp. lactis DSM 10140 8010046 YP_002969435.1 CDS Balat_0425 NC_012815.1 502102 503778 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 502102..503778 Bifidobacterium animalis subsp. lactis DSM 10140 8010047 YP_002969436.1 CDS Balat_0426 NC_012815.1 503900 505459 R COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein complement(503900..505459) Bifidobacterium animalis subsp. lactis DSM 10140 8010048 YP_002969437.1 CDS Balat_0427 NC_012815.1 505550 506170 R hypothetical protein complement(505550..506170) Bifidobacterium animalis subsp. lactis DSM 10140 8010049 YP_002969438.1 CDS Balat_0428 NC_012815.1 506200 508332 R COG0457 FOG: TPR repeat; hypothetical protein complement(506200..508332) Bifidobacterium animalis subsp. lactis DSM 10140 8010050 YP_002969439.1 CDS Balat_0429 NC_012815.1 508387 509097 R COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; two-component system response regulator complement(508387..509097) Bifidobacterium animalis subsp. lactis DSM 10140 8010051 YP_002969440.1 CDS Balat_0430 NC_012815.1 509390 510850 R COG1983 Putative stress-responsive transcriptional regulator; histidine kinase sensor of two component system complement(509390..510850) Bifidobacterium animalis subsp. lactis DSM 10140 8010052 YP_002969441.1 CDS Balat_0431 NC_012815.1 510964 513051 D COG1983 Putative stress-responsive transcriptional regulator; hypothetical protein 510964..513051 Bifidobacterium animalis subsp. lactis DSM 10140 8010053 YP_002969442.1 CDS Balat_0432 NC_012815.1 513068 513712 D hypothetical protein 513068..513712 Bifidobacterium animalis subsp. lactis DSM 10140 8010054 YP_002969443.1 CDS Balat_0433 NC_012815.1 514003 515202 D COG0626 Cystathionine beta-lyases/cystathioninegamma-synthases; cystathionine beta-lyase 514003..515202 Bifidobacterium animalis subsp. lactis DSM 10140 8010055 YP_002969444.1 CDS Balat_0434 NC_012815.1 515249 515950 D COG2873 O-acetylhomoserine sulfhydrylase; cysteine synthase 515249..515950 Bifidobacterium animalis subsp. lactis DSM 10140 8010056 YP_002969445.1 CDS Balat_0435 NC_012815.1 515926 516123 D COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase 515926..516123 Bifidobacterium animalis subsp. lactis DSM 10140 8010057 YP_002969446.1 CDS lysS NC_012815.1 516538 518154 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 516538..518154 Bifidobacterium animalis subsp. lactis DSM 10140 8010059 YP_002969447.1 CDS Balat_0438 NC_012815.1 518305 519366 D hypothetical protein 518305..519366 Bifidobacterium animalis subsp. lactis DSM 10140 8010060 YP_002969448.1 CDS Balat_0439 NC_012815.1 519671 519784 D hypothetical protein 519671..519784 Bifidobacterium animalis subsp. lactis DSM 10140 8010061 YP_002969449.1 CDS Balat_0440 NC_012815.1 520132 521487 D hypothetical protein 520132..521487 Bifidobacterium animalis subsp. lactis DSM 10140 8010062 YP_002969450.1 CDS Balat_0441 NC_012815.1 521698 523056 D COG3579 Aminopeptidase C; aminopeptidase 521698..523056 Bifidobacterium animalis subsp. lactis DSM 10140 8010063 YP_002969451.1 CDS Balat_0442 NC_012815.1 523160 525283 D COG0531 Amino acid transporters; hypothetical protein 523160..525283 Bifidobacterium animalis subsp. lactis DSM 10140 8010064 YP_002969452.1 CDS Balat_0443 NC_012815.1 525401 526894 D COG2939 Carboxypeptidase C (cathepsin A); carboxypeptidase C 525401..526894 Bifidobacterium animalis subsp. lactis DSM 10140 8010065 YP_002969453.1 CDS Balat_0444 NC_012815.1 527103 528632 D COG0531 Amino acid transporters; amino acid transporter 527103..528632 Bifidobacterium animalis subsp. lactis DSM 10140 8010066 YP_002969454.1 CDS Balat_0445 NC_012815.1 528748 529791 D COG1575 1,4-dihydroxy-2-naphthoateoctaprenyl transferase; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 528748..529791 Bifidobacterium animalis subsp. lactis DSM 10140 8010067 YP_002969455.1 CDS gpmA NC_012815.1 529889 530629 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 529889..530629 Bifidobacterium animalis subsp. lactis DSM 10140 8010068 YP_002969456.1 CDS Balat_0447 NC_012815.1 531277 533403 D in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 531277..533403 Bifidobacterium animalis subsp. lactis DSM 10140 8010069 YP_002969457.1 CDS Balat_0448 NC_012815.1 534590 535960 R COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase complement(534590..535960) Bifidobacterium animalis subsp. lactis DSM 10140 8010070 YP_002969458.1 CDS Balat_0449 NC_012815.1 536295 537683 R COG0642 Signal transduction histidine kinase; signal transduction histidine kinase complement(536295..537683) Bifidobacterium animalis subsp. lactis DSM 10140 8010071 YP_002969459.1 CDS Balat_0450 NC_012815.1 537853 538533 D COG0704 Phosphate uptake regulator; two-component system response regulator 537853..538533 Bifidobacterium animalis subsp. lactis DSM 10140 8010072 YP_002969460.1 CDS Balat_0451 NC_012815.1 538690 539802 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase complement(538690..539802) Bifidobacterium animalis subsp. lactis DSM 10140 8010073 YP_002969461.1 CDS Balat_0452 NC_012815.1 540166 541191 D COG3942 Surface antigen; Surface antigen protein 540166..541191 Bifidobacterium animalis subsp. lactis DSM 10140 8010074 YP_002969462.1 CDS Balat_0453 NC_012815.1 541389 541547 D hypothetical protein 541389..541547 Bifidobacterium animalis subsp. lactis DSM 10140 8010075 YP_002969463.1 CDS Balat_0454 NC_012815.1 541662 542471 D COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Cell wall-associated hydrolase 541662..542471 Bifidobacterium animalis subsp. lactis DSM 10140 8010076 YP_002969464.1 CDS Balat_0455 NC_012815.1 542965 544020 D COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein 542965..544020 Bifidobacterium animalis subsp. lactis DSM 10140 8010077 YP_002969465.1 CDS Balat_0456 NC_012815.1 544109 544522 R COG1765 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein complement(544109..544522) Bifidobacterium animalis subsp. lactis DSM 10140 8010078 YP_002969466.1 CDS thyA NC_012815.1 544656 545528 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 544656..545528 Bifidobacterium animalis subsp. lactis DSM 10140 8010079 YP_002969467.1 CDS Balat_0458 NC_012815.1 545654 546337 D COG0262 Dihydrofolate reductase; dihydrofolate reductase 545654..546337 Bifidobacterium animalis subsp. lactis DSM 10140 8010080 YP_002969468.1 CDS Balat_0459 NC_012815.1 546372 546908 D COG0394 Protein-tyrosine-phosphatase; low molecular weight protein-tyrosine-phosphatase 546372..546908 Bifidobacterium animalis subsp. lactis DSM 10140 8010081 YP_002969469.1 CDS Balat_0460 NC_012815.1 547007 548017 R COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(547007..548017) Bifidobacterium animalis subsp. lactis DSM 10140 8010082 YP_002969470.1 CDS Balat_0461 NC_012815.1 548354 549199 D COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; tRNA (guanine-N(7--methyltransferase)) 548354..549199 Bifidobacterium animalis subsp. lactis DSM 10140 8010083 YP_002969471.1 CDS Balat_0463 NC_012815.1 549809 550876 R COG1434 Uncharacterized conserved protein; hypothetical protein complement(549809..550876) Bifidobacterium animalis subsp. lactis DSM 10140 8010085 YP_002969472.1 CDS Balat_0464 NC_012815.1 551023 552018 D putative 5-nucleotidase 551023..552018 Bifidobacterium animalis subsp. lactis DSM 10140 8010086 YP_002969473.1 CDS Balat_0465 NC_012815.1 552272 552697 D COG3642 Mn2+-dependent serine/threonine protein kinase; hypothetical protein 552272..552697 Bifidobacterium animalis subsp. lactis DSM 10140 8010087 YP_002969474.1 CDS Balat_0466 NC_012815.1 552723 554270 D COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 552723..554270 Bifidobacterium animalis subsp. lactis DSM 10140 8010088 YP_002969475.1 CDS Balat_0467 NC_012815.1 554404 554766 D hypothetical protein 554404..554766 Bifidobacterium animalis subsp. lactis DSM 10140 8010089 YP_002969476.1 CDS Balat_0468 NC_012815.1 554757 555560 D cutinase 554757..555560 Bifidobacterium animalis subsp. lactis DSM 10140 8010090 YP_002969477.1 CDS Balat_0469 NC_012815.1 555509 556921 D COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein 555509..556921 Bifidobacterium animalis subsp. lactis DSM 10140 8010091 YP_002969478.1 CDS Balat_0470 NC_012815.1 557035 558609 D hypothetical protein 557035..558609 Bifidobacterium animalis subsp. lactis DSM 10140 8010092 YP_002969479.1 CDS Balat_0471 NC_012815.1 558611 559420 D hypothetical protein 558611..559420 Bifidobacterium animalis subsp. lactis DSM 10140 8010093 YP_002969480.1 CDS Balat_0472 NC_012815.1 559417 562914 D COG4913 Uncharacterized protein conserved in bacteria; hypothetical protein 559417..562914 Bifidobacterium animalis subsp. lactis DSM 10140 8010094 YP_002969481.1 CDS Balat_0473 NC_012815.1 562911 564131 D COG4924 Uncharacterized protein conserved in bacteria; hypothetical protein 562911..564131 Bifidobacterium animalis subsp. lactis DSM 10140 8010095 YP_002969482.1 CDS Balat_0474 NC_012815.1 564499 564891 R COG3189 Uncharacterized conserved protein; hypothetical protein complement(564499..564891) Bifidobacterium animalis subsp. lactis DSM 10140 8010096 YP_002969483.1 CDS lacS NC_012815.1 565134 566651 R COG2211 Na+/melibiose symporter and related transporters; galactoside symporter complement(565134..566651) Bifidobacterium animalis subsp. lactis DSM 10140 8010097 YP_002969484.1 CDS lacZ NC_012815.1 566961 570164 D COG3250 Beta-galactosidase/beta-glucuronidase; LacZ 566961..570164 Bifidobacterium animalis subsp. lactis DSM 10140 8010098 YP_002969485.1 CDS Balat_0477 NC_012815.1 570267 571262 R COG1609 Transcriptional regulators; LacI-type transcriptional regulator complement(570267..571262) Bifidobacterium animalis subsp. lactis DSM 10140 8010099 YP_002969486.1 CDS Balat_0478 NC_012815.1 571696 572304 D COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase 571696..572304 Bifidobacterium animalis subsp. lactis DSM 10140 8010100 YP_002969487.1 CDS Balat_0479 NC_012815.1 572431 572826 R hypothetical protein complement(572431..572826) Bifidobacterium animalis subsp. lactis DSM 10140 8010101 YP_002969488.1 CDS Balat_0480 NC_012815.1 572973 573563 D hypothetical protein 572973..573563 Bifidobacterium animalis subsp. lactis DSM 10140 8010102 YP_002969489.1 CDS Balat_0481 NC_012815.1 573560 573733 D hypothetical protein 573560..573733 Bifidobacterium animalis subsp. lactis DSM 10140 8010103 YP_002969490.1 CDS Balat_0482 NC_012815.1 573743 574243 D hypothetical protein 573743..574243 Bifidobacterium animalis subsp. lactis DSM 10140 8010104 YP_002969491.1 CDS Balat_0483 NC_012815.1 574341 575684 R COG1653 ABC-type sugar transport system, periplasmic component; MalE-type ABC sugar transport system periplasmic component complement(574341..575684) Bifidobacterium animalis subsp. lactis DSM 10140 8010105 YP_002969492.1 CDS Balat_0484 NC_012815.1 575930 578017 R COG1874 Beta-galactosidase; beta-galactosidase complement(575930..578017) Bifidobacterium animalis subsp. lactis DSM 10140 8010106 YP_002969493.1 CDS Balat_0485 NC_012815.1 578059 579039 R COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease complement(578059..579039) Bifidobacterium animalis subsp. lactis DSM 10140 8010107 YP_002969494.1 CDS Balat_0486 NC_012815.1 579059 580027 R COG1175 ABC-type sugar transport systems, permease components; MalF-type ABC sugar transport systems permease complement(579059..580027) Bifidobacterium animalis subsp. lactis DSM 10140 8010108 YP_002969495.1 CDS Balat_0487 NC_012815.1 580314 581312 D COG1609 Transcriptional regulators; LacI-type transcriptional regulator 580314..581312 Bifidobacterium animalis subsp. lactis DSM 10140 8010109 YP_002969496.1 CDS Balat_0491 NC_012815.1 581934 582959 R COG0463 Glycosyl transferases involved in cell wall biogenesis; glycosyltransferase complement(581934..582959) Bifidobacterium animalis subsp. lactis DSM 10140 8010113 YP_002969497.1 CDS Balat_0492 NC_012815.1 583090 584679 D COG0628 Predicted permease; hypothetical protein 583090..584679 Bifidobacterium animalis subsp. lactis DSM 10140 8010114 YP_002969498.1 CDS Balat_0493 NC_012815.1 584679 585965 D COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; hypothetical protein 584679..585965 Bifidobacterium animalis subsp. lactis DSM 10140 8010115 YP_002969499.1 CDS Balat_0494 NC_012815.1 586188 587048 D COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 586188..587048 Bifidobacterium animalis subsp. lactis DSM 10140 8010116 YP_002969500.1 CDS Balat_0495 NC_012815.1 587069 588766 D hypothetical protein 587069..588766 Bifidobacterium animalis subsp. lactis DSM 10140 8010117 YP_002969501.1 CDS Balat_0496 NC_012815.1 588795 589454 D COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase 588795..589454 Bifidobacterium animalis subsp. lactis DSM 10140 8010118 YP_002969502.1 CDS Balat_0497 NC_012815.1 590331 591461 D COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; tRNA(Ile-lysidine synthetase) 590331..591461 Bifidobacterium animalis subsp. lactis DSM 10140 8010119 YP_002969503.1 CDS Balat_0498 NC_012815.1 591430 591993 D COG0634 Hypoxanthine-guaninephosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 591430..591993 Bifidobacterium animalis subsp. lactis DSM 10140 8010120 YP_002969504.1 CDS Balat_0499 NC_012815.1 591990 594086 D COG0465 ATP-dependent Zn proteases; hypothetical protein 591990..594086 Bifidobacterium animalis subsp. lactis DSM 10140 8010121 YP_002969505.1 CDS Balat_0500 NC_012815.1 594172 595041 D Dihydroneopterin aldolase 594172..595041 Bifidobacterium animalis subsp. lactis DSM 10140 8010122 YP_002969506.1 CDS Balat_0501 NC_012815.1 595038 595655 D hypothetical protein 595038..595655 Bifidobacterium animalis subsp. lactis DSM 10140 8010123 YP_002969507.1 CDS Balat_0502 NC_012815.1 595722 596627 R COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase complement(595722..596627) Bifidobacterium animalis subsp. lactis DSM 10140 8010124 YP_002969508.1 CDS Balat_0503 NC_012815.1 596865 598541 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(596865..598541) Bifidobacterium animalis subsp. lactis DSM 10140 8010125 YP_002969509.1 CDS Balat_0504 NC_012815.1 598709 599137 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 598709..599137 Bifidobacterium animalis subsp. lactis DSM 10140 8010126 YP_002969510.1 CDS Balat_0505 NC_012815.1 599169 600455 R COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine thiol-lyase complement(599169..600455) Bifidobacterium animalis subsp. lactis DSM 10140 8010127 YP_002969511.1 CDS Balat_0506 NC_012815.1 600743 601375 D COG4721 Predicted membrane protein; hypothetical protein 600743..601375 Bifidobacterium animalis subsp. lactis DSM 10140 8010128 YP_002969512.1 CDS Balat_0507 NC_012815.1 601657 602565 D hypothetical protein 601657..602565 Bifidobacterium animalis subsp. lactis DSM 10140 8010129 YP_002969513.1 CDS Balat_0509 NC_012815.1 602803 603651 R hypothetical protein complement(602803..603651) Bifidobacterium animalis subsp. lactis DSM 10140 8010131 YP_002969514.1 CDS rpmE NC_012815.1 604073 604282 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 604073..604282 Bifidobacterium animalis subsp. lactis DSM 10140 8010132 YP_002969515.1 CDS Balat_0511 NC_012815.1 604576 605928 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 604576..605928 Bifidobacterium animalis subsp. lactis DSM 10140 8010133 YP_002969516.1 CDS Balat_0512 NC_012815.1 606333 608015 D COG3507 Beta-xylosidase; alpha-L-arabinofuranosidase 606333..608015 Bifidobacterium animalis subsp. lactis DSM 10140 8010134 YP_002969517.1 CDS Balat_0513 NC_012815.1 608028 609032 R COG1609 Transcriptional regulators; LacI family transcriptional regulator complement(608028..609032) Bifidobacterium animalis subsp. lactis DSM 10140 8010135 YP_002969518.1 CDS Balat_0514 NC_012815.1 609363 610640 D COG1653 ABC-type sugar transport system, periplasmic component; putative sugar transporter solute-binding protein 609363..610640 Bifidobacterium animalis subsp. lactis DSM 10140 8010136 YP_002969519.1 CDS Balat_0515 NC_012815.1 610749 611807 D COG1175 ABC-type sugar transport systems, permease components; putative binding protein-dependent transporter 610749..611807 Bifidobacterium animalis subsp. lactis DSM 10140 8010137 YP_002969520.1 CDS Balat_0516 NC_012815.1 611809 612678 D COG0395 ABC-type sugar transport system, permease component; putative binding protein-dependent transporter 611809..612678 Bifidobacterium animalis subsp. lactis DSM 10140 8010138 YP_002969521.1 CDS Balat_0517 NC_012815.1 612756 614381 D COG3507 Beta-xylosidase; Beta-xylosidase 612756..614381 Bifidobacterium animalis subsp. lactis DSM 10140 8010139 YP_002969522.1 CDS Balat_0518 NC_012815.1 614487 616412 D hypothetical protein 614487..616412 Bifidobacterium animalis subsp. lactis DSM 10140 8010140 YP_002969523.1 CDS Balat_0519 NC_012815.1 616649 617812 D COG2272 Carboxylesterase type B; esterase 616649..617812 Bifidobacterium animalis subsp. lactis DSM 10140 8010141 YP_002969524.1 CDS Balat_0520 NC_012815.1 617825 619384 R COG3507 Beta-xylosidase; pyridine nucleotide-disulfide oxidoreductase complement(617825..619384) Bifidobacterium animalis subsp. lactis DSM 10140 8010142 YP_002969525.1 CDS Balat_0521 NC_012815.1 619474 621003 R COG1070 Sugar (pentulose and hexulose kinases); xylulose kinase complement(619474..621003) Bifidobacterium animalis subsp. lactis DSM 10140 8010143 YP_002969526.1 CDS Balat_0522 NC_012815.1 621190 622425 D COG1940 Transcriptional regulator/sugar kinase; NagC-type transcriptional regulator 621190..622425 Bifidobacterium animalis subsp. lactis DSM 10140 8010144 YP_002969527.1 CDS rpmE NC_012815.1 622554 622766 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 622554..622766 Bifidobacterium animalis subsp. lactis DSM 10140 8010145 YP_002969528.1 CDS prfA NC_012815.1 622975 624072 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 622975..624072 Bifidobacterium animalis subsp. lactis DSM 10140 8010146 YP_002969529.1 CDS Balat_0525 NC_012815.1 624133 625047 D COG2890 Methylase of polypeptide chain release factors; methylase of polypeptide chain release factor 624133..625047 Bifidobacterium animalis subsp. lactis DSM 10140 8010147 YP_002969530.1 CDS Balat_0526 NC_012815.1 625177 625845 D COG0009 Putative translation factor (SUA5); Sua5/YciO/YrdC family protein 625177..625845 Bifidobacterium animalis subsp. lactis DSM 10140 8010148 YP_002969531.1 CDS Balat_0527 NC_012815.1 625842 627002 D COG0472 UDP-N-acetylmuramyl pentapeptidephosphotransferase/UDP-N-acetylglucosamine-1- phosphatetransferase; UDP-phosphate-alpha-N- acetylglucosaminyltransferase 625842..627002 Bifidobacterium animalis subsp. lactis DSM 10140 8010149 YP_002969532.1 CDS Balat_0528 NC_012815.1 627372 628826 D COG0516 IMP dehydrogenase/GMP reductase; inosine-5'-monophosphate dehydrogenase 627372..628826 Bifidobacterium animalis subsp. lactis DSM 10140 8010150 YP_002969533.1 CDS Balat_0529 NC_012815.1 629021 629674 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 629021..629674 Bifidobacterium animalis subsp. lactis DSM 10140 8010151 YP_002969534.1 CDS Balat_0530 NC_012815.1 629746 630594 D COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 629746..630594 Bifidobacterium animalis subsp. lactis DSM 10140 8010152 YP_002969535.1 CDS Balat_0531 NC_012815.1 630635 632104 D COG0507 ATP-dependent exoDNAse (exonuclease V, alpha subunit - helicase superfamily I member); helicase 630635..632104 Bifidobacterium animalis subsp. lactis DSM 10140 8010153 YP_002969536.1 CDS Balat_0532 NC_012815.1 632205 632636 D hypothetical protein 632205..632636 Bifidobacterium animalis subsp. lactis DSM 10140 8010154 YP_002969537.1 CDS Balat_0533 NC_012815.1 632741 634558 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 632741..634558 Bifidobacterium animalis subsp. lactis DSM 10140 8010155 YP_002969538.1 CDS Balat_0534 NC_012815.1 634788 635510 D COG0629 Single-stranded DNA-binding protein; hypothetical protein 634788..635510 Bifidobacterium animalis subsp. lactis DSM 10140 8010156 YP_002969539.1 CDS Balat_0535 NC_012815.1 635600 637669 R COG3590 Predicted metalloendopeptidase; M13 family peptidase complement(635600..637669) Bifidobacterium animalis subsp. lactis DSM 10140 8010157 YP_002969540.1 CDS Balat_0536 NC_012815.1 637930 638550 D COG3247 Uncharacterized conserved protein; hypothetical protein 637930..638550 Bifidobacterium animalis subsp. lactis DSM 10140 8010158 YP_002969541.1 CDS Balat_0537 NC_012815.1 638701 639504 D COG0024 Methionine aminopeptidase; methionine aminopeptidase 638701..639504 Bifidobacterium animalis subsp. lactis DSM 10140 8010159 YP_002969542.1 CDS Balat_0538 NC_012815.1 639729 641021 D COG0372 Citrate synthase; citrate synthase 1 639729..641021 Bifidobacterium animalis subsp. lactis DSM 10140 8010160 YP_002969543.1 CDS Balat_0539 NC_012815.1 641043 641522 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(641043..641522) Bifidobacterium animalis subsp. lactis DSM 10140 8010161 YP_002969544.1 CDS Balat_0540 NC_012815.1 641631 642614 R COG2171 TetrahydrodipicolinateN-succinyltransferase; hypothetical protein complement(641631..642614) Bifidobacterium animalis subsp. lactis DSM 10140 8010162 YP_002969545.1 CDS Balat_0541 NC_012815.1 642922 643053 D hypothetical protein 642922..643053 Bifidobacterium animalis subsp. lactis DSM 10140 8010163 YP_002969546.1 CDS prfB NC_012815.1 643207 644340 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 643207..644340 Bifidobacterium animalis subsp. lactis DSM 10140 8010164 YP_002969547.1 CDS Balat_0543 NC_012815.1 644386 645714 D COG2884 Predicted ATPase involved in cell division; FtsE-like ATP binding protein in cell division 644386..645714 Bifidobacterium animalis subsp. lactis DSM 10140 8010165 YP_002969548.1 CDS Balat_0544 NC_012815.1 645718 646641 D COG2177 Cell division protein; FtsX-like protein 645718..646641 Bifidobacterium animalis subsp. lactis DSM 10140 8010166 YP_002969549.1 CDS Balat_0545 NC_012815.1 646867 648210 D COG3942 Surface antigen; Surface antigen 646867..648210 Bifidobacterium animalis subsp. lactis DSM 10140 8010167 YP_002969550.1 CDS smpB NC_012815.1 648609 649100 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 648609..649100 Bifidobacterium animalis subsp. lactis DSM 10140 8010168 YP_002969551.1 CDS Balat_0547 NC_012815.1 649179 649418 D hypothetical protein 649179..649418 Bifidobacterium animalis subsp. lactis DSM 10140 8010169 YP_002969552.1 CDS Balat_0548 NC_012815.1 649465 650394 D COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; ABC transporter substrate-binding protein 649465..650394 Bifidobacterium animalis subsp. lactis DSM 10140 8010170 YP_002969553.1 CDS Balat_0549 NC_012815.1 650609 651544 D COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; ABC transporter substrate-binding protein 650609..651544 Bifidobacterium animalis subsp. lactis DSM 10140 8010171 YP_002969554.1 CDS Balat_0550 NC_012815.1 651741 652727 D COG0765 ABC-type amino acid transport system, permease component; ABC transporter permease 651741..652727 Bifidobacterium animalis subsp. lactis DSM 10140 8010172 YP_002969555.1 CDS Balat_0551 NC_012815.1 652755 653609 D COG1126 ABC-type polar amino acid transport system, ATPase component; ABC transporter ATP-binding protein 652755..653609 Bifidobacterium animalis subsp. lactis DSM 10140 8010173 YP_002969556.1 CDS Balat_0552 NC_012815.1 654084 655019 R hypothetical protein complement(654084..655019) Bifidobacterium animalis subsp. lactis DSM 10140 8010174 YP_002969557.1 CDS Balat_0553 NC_012815.1 656516 657202 R COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator complement(656516..657202) Bifidobacterium animalis subsp. lactis DSM 10140 8010175 YP_002969558.1 CDS Balat_0554 NC_012815.1 657538 659364 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 657538..659364 Bifidobacterium animalis subsp. lactis DSM 10140 8010176 YP_002969559.1 CDS Balat_0555 NC_012815.1 659382 660110 D COG0564 Pseudouridylate synthases, 23SRNA-specific; 23S RNA-specific pseudouridylate synthase 659382..660110 Bifidobacterium animalis subsp. lactis DSM 10140 8010177 YP_002969560.1 CDS Balat_0556 NC_012815.1 660148 660549 D hypothetical protein 660148..660549 Bifidobacterium animalis subsp. lactis DSM 10140 8010178 YP_002969561.1 CDS Balat_0557 NC_012815.1 660556 661314 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(660556..661314) Bifidobacterium animalis subsp. lactis DSM 10140 8010179 YP_002969562.1 CDS Balat_0558 NC_012815.1 661484 663235 D COG0747 ABC-type dipeptide transport system, periplasmic component; dipeptide ABC transporter periplasmic protein 661484..663235 Bifidobacterium animalis subsp. lactis DSM 10140 8010180 YP_002969563.1 CDS Balat_0559 NC_012815.1 663275 664237 D COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 663275..664237 Bifidobacterium animalis subsp. lactis DSM 10140 8010181 YP_002969564.1 CDS Balat_0560 NC_012815.1 664230 665114 D COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease 664230..665114 Bifidobacterium animalis subsp. lactis DSM 10140 8010182 YP_002969565.1 CDS Balat_0561 NC_012815.1 665111 665908 D COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; peptide ABC transporter ATP-binding protein 665111..665908 Bifidobacterium animalis subsp. lactis DSM 10140 8010183 YP_002969566.1 CDS Balat_0562 NC_012815.1 665901 666689 D COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; oligopeptide ABC transporter ATPase 665901..666689 Bifidobacterium animalis subsp. lactis DSM 10140 8010184 YP_002969567.1 CDS Balat_0563 NC_012815.1 666779 667954 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(666779..667954) Bifidobacterium animalis subsp. lactis DSM 10140 8010185 YP_002969568.1 CDS Balat_0564 NC_012815.1 668031 669050 R COG0031 Cysteine synthase; cystathionine beta-synthase complement(668031..669050) Bifidobacterium animalis subsp. lactis DSM 10140 8010186 YP_002969569.1 CDS Balat_0565 NC_012815.1 669436 671394 R COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ complement(669436..671394) Bifidobacterium animalis subsp. lactis DSM 10140 8010187 YP_002969570.1 CDS Balat_0566 NC_012815.1 671696 672616 D COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 671696..672616 Bifidobacterium animalis subsp. lactis DSM 10140 8010188 YP_002969571.1 CDS Balat_0567 NC_012815.1 672789 673346 R COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein complement(672789..673346) Bifidobacterium animalis subsp. lactis DSM 10140 8010189 YP_002969572.1 CDS Balat_0568 NC_012815.1 673627 673755 D hypothetical protein 673627..673755 Bifidobacterium animalis subsp. lactis DSM 10140 8010190 YP_002969573.1 CDS Balat_0569 NC_012815.1 673887 674090 R hypothetical protein complement(673887..674090) Bifidobacterium animalis subsp. lactis DSM 10140 8010191 YP_002969574.1 CDS Balat_0570 NC_012815.1 674625 674945 D hypothetical protein 674625..674945 Bifidobacterium animalis subsp. lactis DSM 10140 8010192 YP_002969575.1 CDS Balat_0571 NC_012815.1 675087 675428 D hypothetical protein 675087..675428 Bifidobacterium animalis subsp. lactis DSM 10140 8010193 YP_002969576.1 CDS Balat_0572 NC_012815.1 675452 675835 R hypothetical protein complement(675452..675835) Bifidobacterium animalis subsp. lactis DSM 10140 8010194 YP_002969577.1 CDS Balat_0573 NC_012815.1 676005 676406 D COG0494 NTP pyrophosphohydrolases includingoxidative damage repair enzymes; putative pyrophosphohydrolase 676005..676406 Bifidobacterium animalis subsp. lactis DSM 10140 8010195 YP_002969578.1 CDS Balat_0574 NC_012815.1 676459 679584 D COG3886 Predicted HKD family nuclease; superfamily II DNA/RNA helicase 676459..679584 Bifidobacterium animalis subsp. lactis DSM 10140 8010196 YP_002969579.1 CDS Balat_0575 NC_012815.1 680209 680565 D COG3177 Uncharacterized conserved protein; hypothetical protein 680209..680565 Bifidobacterium animalis subsp. lactis DSM 10140 8010197 YP_002969580.1 CDS Balat_0576 NC_012815.1 680998 682965 D COG1479 Uncharacterized conserved protein; type I restriction-modification system protein 680998..682965 Bifidobacterium animalis subsp. lactis DSM 10140 8010198 YP_002969581.1 CDS Balat_0577 NC_012815.1 683204 683716 D COG3600 Uncharacterized phage-associated protein; putative prophage protein 683204..683716 Bifidobacterium animalis subsp. lactis DSM 10140 8010199 YP_002969582.1 CDS Balat_0578 NC_012815.1 683734 684228 D COG3654 Prophage maintenance system killer protein; hypothetical protein 683734..684228 Bifidobacterium animalis subsp. lactis DSM 10140 8010200 YP_002969583.1 CDS Balat_0579 NC_012815.1 684225 684704 R COG1247 Sortase and related acyltransferases; hypothetical protein complement(684225..684704) Bifidobacterium animalis subsp. lactis DSM 10140 8010201 YP_002969584.1 CDS Balat_0580 NC_012815.1 684771 685568 R COG3752 Predicted membrane protein; hypothetical protein complement(684771..685568) Bifidobacterium animalis subsp. lactis DSM 10140 8010202 YP_002969585.1 CDS Balat_0581 NC_012815.1 685676 686689 R COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase complement(685676..686689) Bifidobacterium animalis subsp. lactis DSM 10140 8010203 YP_002969586.1 CDS Balat_0582 NC_012815.1 687070 687570 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 687070..687570 Bifidobacterium animalis subsp. lactis DSM 10140 8010204 YP_002969587.1 CDS Balat_0583 NC_012815.1 687683 688207 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Histone acetyltransferase 687683..688207 Bifidobacterium animalis subsp. lactis DSM 10140 8010205 YP_002969588.1 CDS Balat_0584 NC_012815.1 688283 689650 D COG0787 Alanine racemase; alanine racemase 688283..689650 Bifidobacterium animalis subsp. lactis DSM 10140 8010206 YP_002969589.1 CDS dnaG NC_012815.1 689760 691841 D synthesizes RNA primers at the replication forks; DNA primase 689760..691841 Bifidobacterium animalis subsp. lactis DSM 10140 8010207 YP_002969590.1 CDS Balat_0586 NC_012815.1 692056 693249 D COG0471 Di- and tricarboxylate transporters; transport protein 692056..693249 Bifidobacterium animalis subsp. lactis DSM 10140 8010208 YP_002969591.1 CDS Balat_0588 NC_012815.1 693551 695398 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(693551..695398) Bifidobacterium animalis subsp. lactis DSM 10140 8010210 YP_002969592.1 CDS Balat_0589 NC_012815.1 695658 696155 D COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR mutase); phosphoribosylaminoimidazole carboxylasecatalytic subunit 695658..696155 Bifidobacterium animalis subsp. lactis DSM 10140 8010211 YP_002969593.1 CDS Balat_0590 NC_012815.1 696139 697290 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 696139..697290 Bifidobacterium animalis subsp. lactis DSM 10140 8010212 YP_002969594.1 CDS Balat_0591 NC_012815.1 697331 697732 D COG0735 Fe2+/Zn2+ uptake regulation proteins; metal uptake regulator ferric uptake regulator protein 697331..697732 Bifidobacterium animalis subsp. lactis DSM 10140 8010213 YP_002969595.1 CDS Balat_0592 NC_012815.1 697833 700601 R COG2898 Uncharacterized conserved protein; hypothetical protein complement(697833..700601) Bifidobacterium animalis subsp. lactis DSM 10140 8010214 YP_002969596.1 CDS Balat_0593 NC_012815.1 700598 701971 R COG0627 Predicted esterase; putative esterase complement(700598..701971) Bifidobacterium animalis subsp. lactis DSM 10140 8010215 YP_002969597.1 CDS Balat_0594 NC_012815.1 702164 703426 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(702164..703426) Bifidobacterium animalis subsp. lactis DSM 10140 8010216 YP_002969598.1 CDS Balat_0595 NC_012815.1 703474 704508 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(703474..704508) Bifidobacterium animalis subsp. lactis DSM 10140 8010217 YP_002969599.1 CDS Balat_0596 NC_012815.1 704585 706141 R COG0034 Glutamine phosphoribosylpyrophosphateamidotransferase; amidophosphoribosyltransferase complement(704585..706141) Bifidobacterium animalis subsp. lactis DSM 10140 8010218 YP_002969600.1 CDS Balat_0597 NC_012815.1 706394 707872 D COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA-repair protein 706394..707872 Bifidobacterium animalis subsp. lactis DSM 10140 8010219 YP_002969601.1 CDS Balat_0598 NC_012815.1 707869 708282 D hypothetical protein 707869..708282 Bifidobacterium animalis subsp. lactis DSM 10140 8010220 YP_002969602.1 CDS Balat_0599 NC_012815.1 708289 709572 D COG3597 Uncharacterized protein/domain associated with GTPases; GTPase protein 708289..709572 Bifidobacterium animalis subsp. lactis DSM 10140 8010221 YP_002969603.1 CDS Balat_0600 NC_012815.1 709735 710406 D hypothetical protein 709735..710406 Bifidobacterium animalis subsp. lactis DSM 10140 8010222 YP_002969604.1 CDS Balat_0601 NC_012815.1 710574 711083 R COG3467 Predicted flavin-nucleotide-binding protein; hypothetical protein complement(710574..711083) Bifidobacterium animalis subsp. lactis DSM 10140 8010223 YP_002969605.1 CDS Balat_0602 NC_012815.1 711268 711864 R COG1396 Predicted transcriptional regulators; hypothetical protein complement(711268..711864) Bifidobacterium animalis subsp. lactis DSM 10140 8010224 YP_002969606.1 CDS Balat_0603 NC_012815.1 711993 712169 R hypothetical protein complement(711993..712169) Bifidobacterium animalis subsp. lactis DSM 10140 8010225 YP_002969607.1 CDS Balat_0604 NC_012815.1 712168 712311 D hypothetical protein 712168..712311 Bifidobacterium animalis subsp. lactis DSM 10140 8010226 YP_002969608.1 CDS Balat_0605 NC_012815.1 712415 713953 D hypothetical protein 712415..713953 Bifidobacterium animalis subsp. lactis DSM 10140 8010227 YP_002969609.1 CDS Balat_0606 NC_012815.1 713979 714707 D hypothetical protein 713979..714707 Bifidobacterium animalis subsp. lactis DSM 10140 8010228 YP_002969610.1 CDS Balat_0607 NC_012815.1 714748 715197 D hypothetical protein 714748..715197 Bifidobacterium animalis subsp. lactis DSM 10140 8010229 YP_002969611.1 CDS Balat_0608 NC_012815.1 715271 715855 D hypothetical protein 715271..715855 Bifidobacterium animalis subsp. lactis DSM 10140 8010230 YP_002969612.1 CDS Balat_0609 NC_012815.1 715887 717119 D COG4260 Putative virion core protein (lumpy skin disease virus); putative virion core protein 715887..717119 Bifidobacterium animalis subsp. lactis DSM 10140 8010231 YP_002969613.1 CDS Balat_0610 NC_012815.1 717421 721155 R COG0046 Phosphoribosylformylglycinamidine (FGAM synthase, synthetase domain); hypothetical protein complement(717421..721155) Bifidobacterium animalis subsp. lactis DSM 10140 8010232 YP_002969614.1 CDS Balat_0611 NC_012815.1 721265 722017 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(721265..722017) Bifidobacterium animalis subsp. lactis DSM 10140 8010233 YP_002969615.1 CDS purT NC_012815.1 722154 723395 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(722154..723395) Bifidobacterium animalis subsp. lactis DSM 10140 8010234 YP_002969616.1 CDS Balat_0613 NC_012815.1 723521 724723 D COG0438 Glycosyltransferase; glycosyltransferase 723521..724723 Bifidobacterium animalis subsp. lactis DSM 10140 8010235 YP_002969617.1 CDS Balat_0614 NC_012815.1 724792 725817 R COG2008 Threonine aldolase; low specificity-threonine aldolase complement(724792..725817) Bifidobacterium animalis subsp. lactis DSM 10140 8010236 YP_002969618.1 CDS Balat_0616 NC_012815.1 726588 726722 D hypothetical protein 726588..726722 Bifidobacterium animalis subsp. lactis DSM 10140 8010238 YP_002969619.2 CDS rpsL NC_012815.1 726998 727369 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 726998..727369 Bifidobacterium animalis subsp. lactis DSM 10140 8010239 YP_002969620.1 CDS Balat_0618 NC_012815.1 727375 727845 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 727375..727845 Bifidobacterium animalis subsp. lactis DSM 10140 8010240 YP_002969621.1 CDS Balat_0619 NC_012815.1 727879 730008 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 727879..730008 Bifidobacterium animalis subsp. lactis DSM 10140 8010241 YP_002969622.1 CDS Balat_0620 NC_012815.1 730186 731385 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 730186..731385 Bifidobacterium animalis subsp. lactis DSM 10140 8010242 YP_002969623.1 CDS Balat_0621 NC_012815.1 731667 732341 R hypothetical protein complement(731667..732341) Bifidobacterium animalis subsp. lactis DSM 10140 8010243 YP_002969624.1 CDS Balat_0622 NC_012815.1 732482 733051 R COG0492 Thioredoxin reductase; hypothetical protein complement(732482..733051) Bifidobacterium animalis subsp. lactis DSM 10140 8010244 YP_002969625.1 CDS Balat_0623 NC_012815.1 733326 733889 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 733326..733889 Bifidobacterium animalis subsp. lactis DSM 10140 8010245 YP_002969626.1 CDS Balat_0624 NC_012815.1 733986 734450 D COG0781 Transcription termination factor; transcription termination factor 733986..734450 Bifidobacterium animalis subsp. lactis DSM 10140 8010246 YP_002969627.1 CDS Balat_0625 NC_012815.1 734524 735759 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 734524..735759 Bifidobacterium animalis subsp. lactis DSM 10140 8010247 YP_002969628.1 CDS Balat_0626 NC_012815.1 735752 739162 D COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoylphosphate synthase large subunit 735752..739162 Bifidobacterium animalis subsp. lactis DSM 10140 8010248 YP_002969629.1 CDS Balat_0627 NC_012815.1 739159 740130 D COG0284 Orotidine-5-phosphate decarboxylase; orotidine 5-phosphate decarboxylase 739159..740130 Bifidobacterium animalis subsp. lactis DSM 10140 8010249 YP_002969630.1 CDS gmk NC_012815.1 740127 740756 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 740127..740756 Bifidobacterium animalis subsp. lactis DSM 10140 8010250 YP_002969631.1 CDS Balat_0629 NC_012815.1 740853 742688 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(740853..742688) Bifidobacterium animalis subsp. lactis DSM 10140 8010251 YP_002969632.1 CDS Balat_0630 NC_012815.1 742885 743169 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 742885..743169 Bifidobacterium animalis subsp. lactis DSM 10140 8010252 YP_002969633.1 CDS Balat_0631 NC_012815.1 743350 744576 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 743350..744576 Bifidobacterium animalis subsp. lactis DSM 10140 8010253 YP_002969634.1 CDS Balat_0632 NC_012815.1 744696 745979 D COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane-fatty-acyl-phospholipid synthase 744696..745979 Bifidobacterium animalis subsp. lactis DSM 10140 8010254 YP_002969635.1 CDS Balat_0633 NC_012815.1 746133 748376 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 746133..748376 Bifidobacterium animalis subsp. lactis DSM 10140 8010255 YP_002969636.1 CDS Balat_0634 NC_012815.1 748548 749459 D COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 748548..749459 Bifidobacterium animalis subsp. lactis DSM 10140 8010256 YP_002969637.1 CDS Balat_0635 NC_012815.1 749559 750260 R COG0560 Phosphoserine phosphatase; phosphoserine phosphatase complement(749559..750260) Bifidobacterium animalis subsp. lactis DSM 10140 8010257 YP_002969638.1 CDS Balat_0636 NC_012815.1 750370 750993 D COG0586 Uncharacterized membrane-associated protein; hypothetical protein 750370..750993 Bifidobacterium animalis subsp. lactis DSM 10140 8010258 YP_002969639.1 CDS Balat_0637 NC_012815.1 751119 752687 D COG0464 ATPases of the AAA+ class; ATPase AAA 751119..752687 Bifidobacterium animalis subsp. lactis DSM 10140 8010259 YP_002969640.1 CDS Balat_0638 NC_012815.1 752770 754374 D proteasome-associated protein 752770..754374 Bifidobacterium animalis subsp. lactis DSM 10140 8010260 YP_002969641.1 CDS Balat_0639 NC_012815.1 754494 755387 D COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol monophosphatase 754494..755387 Bifidobacterium animalis subsp. lactis DSM 10140 8010261 YP_002969642.1 CDS Balat_0640 NC_012815.1 755476 755691 D hypothetical protein 755476..755691 Bifidobacterium animalis subsp. lactis DSM 10140 8010262 YP_002969643.1 CDS Balat_0641 NC_012815.1 755691 757181 D proteasome-associated protein 755691..757181 Bifidobacterium animalis subsp. lactis DSM 10140 8010263 YP_002969644.1 CDS Balat_0642 NC_012815.1 757259 757540 R COG0776 Bacterial nucleoid DNA-binding protein; DNA-binding protein HB1 complement(757259..757540) Bifidobacterium animalis subsp. lactis DSM 10140 8010264 YP_002969645.1 CDS Balat_0643 NC_012815.1 757707 760211 R COG0392 Predicted integral membrane protein; hypothetical protein complement(757707..760211) Bifidobacterium animalis subsp. lactis DSM 10140 8010265 YP_002969646.1 CDS Balat_0644 NC_012815.1 760310 761755 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(760310..761755) Bifidobacterium animalis subsp. lactis DSM 10140 8010266 YP_002969647.1 CDS Balat_0645 NC_012815.1 761806 763356 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein complement(761806..763356) Bifidobacterium animalis subsp. lactis DSM 10140 8010267 YP_002969648.1 CDS Balat_0646 NC_012815.1 763365 763643 R hypothetical protein complement(763365..763643) Bifidobacterium animalis subsp. lactis DSM 10140 8010268 YP_002969649.1 CDS Balat_0647 NC_012815.1 763774 764373 R cell surface elastin binding protein EbpS complement(763774..764373) Bifidobacterium animalis subsp. lactis DSM 10140 8010269 YP_002969650.1 CDS Balat_0648 NC_012815.1 764370 765374 R hypothetical protein complement(764370..765374) Bifidobacterium animalis subsp. lactis DSM 10140 8010270 YP_002969651.1 CDS Balat_0649 NC_012815.1 765371 766432 R COG2304 Uncharacterized protein containing a vonWillebrand factor type A (vWA domain); von Willebrand factor A complement(765371..766432) Bifidobacterium animalis subsp. lactis DSM 10140 8010271 YP_002969652.1 CDS Balat_0650 NC_012815.1 766429 766941 R hypothetical protein complement(766429..766941) Bifidobacterium animalis subsp. lactis DSM 10140 8010272 YP_002969653.1 CDS Balat_0651 NC_012815.1 766942 767907 R COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWAdomain)); hypothetical protein complement(766942..767907) Bifidobacterium animalis subsp. lactis DSM 10140 8010273 YP_002969654.1 CDS Balat_0652 NC_012815.1 767904 768860 R COG0714 MoxR-like ATPases; magnesium chelatase family protein complement(767904..768860) Bifidobacterium animalis subsp. lactis DSM 10140 8010274 YP_002969655.1 CDS Balat_0653 NC_012815.1 769327 769815 R COG0692 Uracil DNA glycosylase; uracil-DNA glycosylase complement(769327..769815) Bifidobacterium animalis subsp. lactis DSM 10140 8010275 YP_002969656.1 CDS Balat_0654 NC_012815.1 769992 770675 D hypothetical protein 769992..770675 Bifidobacterium animalis subsp. lactis DSM 10140 8010276 YP_002969657.1 CDS cspA NC_012815.1 770982 771194 D COG1278 Cold shock proteins; cold-shock DNA-binding domain-containing protein 770982..771194 Bifidobacterium animalis subsp. lactis DSM 10140 8010277 YP_002969658.1 CDS groEL NC_012815.1 771410 773023 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 771410..773023 Bifidobacterium animalis subsp. lactis DSM 10140 8010278 YP_002969659.1 CDS Balat_0657 NC_012815.1 773163 773456 R hypothetical protein complement(773163..773456) Bifidobacterium animalis subsp. lactis DSM 10140 8010279 YP_002969660.1 CDS Balat_0658 NC_012815.1 773534 774541 D hypothetical protein 773534..774541 Bifidobacterium animalis subsp. lactis DSM 10140 8010280 YP_002969661.1 CDS Balat_0659 NC_012815.1 774622 775332 D COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 774622..775332 Bifidobacterium animalis subsp. lactis DSM 10140 8010281 YP_002969662.1 CDS Balat_0660 NC_012815.1 775406 777151 D COG0642 Signal transduction histidine kinase; sensor protein 775406..777151 Bifidobacterium animalis subsp. lactis DSM 10140 8010282 YP_002969663.1 CDS cspB NC_012815.1 777278 777721 D COG1278 Cold shock proteins; cold shock protein 777278..777721 Bifidobacterium animalis subsp. lactis DSM 10140 8010283 YP_002969664.1 CDS Balat_0662 NC_012815.1 777723 778853 D hypothetical protein 777723..778853 Bifidobacterium animalis subsp. lactis DSM 10140 8010284 YP_002969665.1 CDS Balat_0663 NC_012815.1 778936 779958 R hypothetical protein complement(778936..779958) Bifidobacterium animalis subsp. lactis DSM 10140 8010285 YP_002969666.1 CDS Balat_0664 NC_012815.1 780123 781100 R COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein complement(780123..781100) Bifidobacterium animalis subsp. lactis DSM 10140 8010286 YP_002969667.1 CDS clpC NC_012815.1 781407 783959 D COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 781407..783959 Bifidobacterium animalis subsp. lactis DSM 10140 8010287 YP_002969668.1 CDS aspS NC_012815.1 784361 786163 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(784361..786163) Bifidobacterium animalis subsp. lactis DSM 10140 8010288 YP_002969669.1 CDS hisS NC_012815.1 786222 787568 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(786222..787568) Bifidobacterium animalis subsp. lactis DSM 10140 8010289 YP_002969670.1 CDS Balat_0668 NC_012815.1 787756 789174 D hypothetical protein 787756..789174 Bifidobacterium animalis subsp. lactis DSM 10140 8010290 YP_002969671.1 CDS Balat_0669 NC_012815.1 789353 790141 D COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 789353..790141 Bifidobacterium animalis subsp. lactis DSM 10140 8010291 YP_002969672.1 CDS Balat_0670 NC_012815.1 790310 791095 D COG1126 ABC-type polar amino acid transport system, ATPase component; ATP-binding protein of ABC transporter for glutamate 790310..791095 Bifidobacterium animalis subsp. lactis DSM 10140 8010292 YP_002969673.1 CDS Balat_0671 NC_012815.1 791181 792020 D COG0834 ABC-type amino acid transport/signaltransduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein 791181..792020 Bifidobacterium animalis subsp. lactis DSM 10140 8010293 YP_002969674.1 CDS Balat_0672 NC_012815.1 792026 792703 D COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 792026..792703 Bifidobacterium animalis subsp. lactis DSM 10140 8010294 YP_002969675.1 CDS Balat_0673 NC_012815.1 792707 793798 D COG0765 ABC-type amino acid transport system, permease component; glutamate ABC transporter permease 792707..793798 Bifidobacterium animalis subsp. lactis DSM 10140 8010295 YP_002969676.1 CDS Balat_0674 NC_012815.1 793911 794879 D COG2326 Uncharacterized conserved protein; hypothetical protein 793911..794879 Bifidobacterium animalis subsp. lactis DSM 10140 8010296 YP_002969677.1 CDS Balat_0675 NC_012815.1 794894 797482 R COG4581 Superfamily II RNA helicase; DEAD box-like helicase complement(794894..797482) Bifidobacterium animalis subsp. lactis DSM 10140 8010297 YP_002969678.1 CDS Balat_0676 NC_012815.1 797613 799127 D COG2256 ATPase related to the helicase subunit ofthe Holliday junction resolvase; recombination factor protein RarA 797613..799127 Bifidobacterium animalis subsp. lactis DSM 10140 8010298 YP_002969679.1 CDS Balat_0677 NC_012815.1 799069 800571 D COG0477 Permeases of the major facilitator superfamily; efflux-type transporter 799069..800571 Bifidobacterium animalis subsp. lactis DSM 10140 8010299 YP_002969680.1 CDS Balat_0678 NC_012815.1 800649 802484 R COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty-acid--CoA ligase complement(800649..802484) Bifidobacterium animalis subsp. lactis DSM 10140 8010300 YP_002969681.1 CDS Balat_0679 NC_012815.1 802765 803844 D COG3328 Transposase and inactivated derivatives; transposase 802765..803844 Bifidobacterium animalis subsp. lactis DSM 10140 8010301 YP_002969682.1 CDS Balat_0680 NC_012815.1 803904 804026 D hypothetical protein 803904..804026 Bifidobacterium animalis subsp. lactis DSM 10140 8010302 YP_002969683.1 CDS Balat_0681 NC_012815.1 804311 805876 D COG4715 Uncharacterized conserved protein; hypothetical protein 804311..805876 Bifidobacterium animalis subsp. lactis DSM 10140 8010303 YP_002969684.1 CDS Balat_0682 NC_012815.1 805982 806638 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 805982..806638 Bifidobacterium animalis subsp. lactis DSM 10140 8010304 YP_002969685.1 CDS Balat_0683 NC_012815.1 806655 807023 D COG3824 Uncharacterized protein conserved in bacteria; putative Zn-dependent protease 806655..807023 Bifidobacterium animalis subsp. lactis DSM 10140 8010305 YP_002969686.1 CDS Balat_0684 NC_012815.1 807102 807512 R COG3304 Predicted membrane protein; hypothetical protein complement(807102..807512) Bifidobacterium animalis subsp. lactis DSM 10140 8010306 YP_002969687.1 CDS Balat_0685 NC_012815.1 807667 808407 D COG0819 Putative transcription activator; transcriptional activator TenA 807667..808407 Bifidobacterium animalis subsp. lactis DSM 10140 8010307 YP_002969688.1 CDS Balat_0686 NC_012815.1 808530 808835 R COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; hypothetical protein complement(808530..808835) Bifidobacterium animalis subsp. lactis DSM 10140 8010308 YP_002969689.1 CDS Balat_0687 NC_012815.1 809106 809942 R COG0656 Aldo/keto reductases, related to diketogulonate reductase; morphine 6-dehydrogenase complement(809106..809942) Bifidobacterium animalis subsp. lactis DSM 10140 8010309 YP_002969690.1 CDS Balat_0688 NC_012815.1 810303 812600 R COG1122 ABC-type cobalt transport system, ATPase component; cobalt import ATP-binding/permease cbiO complement(810303..812600) Bifidobacterium animalis subsp. lactis DSM 10140 8010310 YP_002969691.1 CDS Balat_0689 NC_012815.1 812597 813088 R COG3601 Predicted membrane protein; hypothetical protein complement(812597..813088) Bifidobacterium animalis subsp. lactis DSM 10140 8010311 YP_002969692.1 CDS Balat_0690 NC_012815.1 813634 814404 D COG1940 Transcriptional regulator/sugar kinase; polyphosphate glucokinase 813634..814404 Bifidobacterium animalis subsp. lactis DSM 10140 8010312 YP_002969693.1 CDS Balat_0691 NC_012815.1 814584 815669 D COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 814584..815669 Bifidobacterium animalis subsp. lactis DSM 10140 8010313 YP_002969694.1 CDS Balat_0692 NC_012815.1 815648 816463 R COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein complement(815648..816463) Bifidobacterium animalis subsp. lactis DSM 10140 8010314 YP_002969695.1 CDS Balat_0693 NC_012815.1 816533 818746 R hypothetical protein complement(816533..818746) Bifidobacterium animalis subsp. lactis DSM 10140 8010315 YP_002969696.1 CDS Balat_0694 NC_012815.1 818829 822158 D hypothetical protein 818829..822158 Bifidobacterium animalis subsp. lactis DSM 10140 8010316 YP_002969697.1 CDS Balat_0695 NC_012815.1 822272 824863 D COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); LigA 822272..824863 Bifidobacterium animalis subsp. lactis DSM 10140 8010317 YP_002969698.1 CDS Balat_0696 NC_012815.1 824933 826045 R COG0489 ATPases involved in chromosome partitioning; hypothetical protein complement(824933..826045) Bifidobacterium animalis subsp. lactis DSM 10140 8010318 YP_002969699.1 CDS Balat_0697 NC_012815.1 826176 826784 R COG4721 Predicted membrane protein; hypothetical protein complement(826176..826784) Bifidobacterium animalis subsp. lactis DSM 10140 8010319 YP_002969700.1 CDS Balat_0698 NC_012815.1 827022 828458 R COG0174 Glutamine synthetase; glutamine synthetase 1 complement(827022..828458) Bifidobacterium animalis subsp. lactis DSM 10140 8010320 YP_002969701.1 CDS Balat_0699 NC_012815.1 828742 829488 R COG0532 Translation initiation factor 2 (IF-2; GTPase); hypothetical protein complement(828742..829488) Bifidobacterium animalis subsp. lactis DSM 10140 8010321 YP_002969702.1 CDS Balat_0700 NC_012815.1 829629 831110 R COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3 component, and related enzymes); dihydrolipoamide dehydrogenase complement(829629..831110) Bifidobacterium animalis subsp. lactis DSM 10140 8010322 YP_002969703.1 CDS Balat_0701 NC_012815.1 831331 831939 R hypothetical protein complement(831331..831939) Bifidobacterium animalis subsp. lactis DSM 10140 8010323 YP_002969704.1 CDS Balat_0702 NC_012815.1 832050 833417 D COG0624 Acetylornithinedeacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; hypothetical protein 832050..833417 Bifidobacterium animalis subsp. lactis DSM 10140 8010324 YP_002969705.1 CDS Balat_0703 NC_012815.1 833656 834777 D COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 833656..834777 Bifidobacterium animalis subsp. lactis DSM 10140 8010325 YP_002969706.1 CDS Balat_0704 NC_012815.1 834796 835236 R hypothetical protein complement(834796..835236) Bifidobacterium animalis subsp. lactis DSM 10140 8010326 YP_002969707.1 CDS Balat_0705 NC_012815.1 835342 835584 D hypothetical protein 835342..835584 Bifidobacterium animalis subsp. lactis DSM 10140 8010327 YP_002969708.1 CDS Balat_0706 NC_012815.1 835980 836834 D COG3409 Putative peptidoglycan-binding domain-containing protein; hypothetical protein 835980..836834 Bifidobacterium animalis subsp. lactis DSM 10140 8010328 YP_002969709.1 CDS Balat_0707 NC_012815.1 836815 836931 D hypothetical protein 836815..836931 Bifidobacterium animalis subsp. lactis DSM 10140 8010329 YP_002969710.1 CDS Balat_0708 NC_012815.1 837276 838481 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 837276..838481 Bifidobacterium animalis subsp. lactis DSM 10140 8010330 YP_002969711.1 CDS Balat_0709 NC_012815.1 838517 838660 D hypothetical protein 838517..838660 Bifidobacterium animalis subsp. lactis DSM 10140 8010331 YP_002969712.1 CDS Balat_0710 NC_012815.1 838896 839516 D COG4721 Predicted membrane protein; hypothetical protein 838896..839516 Bifidobacterium animalis subsp. lactis DSM 10140 8010332 YP_002969713.1 CDS Balat_0711 NC_012815.1 839557 842112 D COG1122 ABC-type cobalt transport system, ATPase component; ABC transporter ATP-binding protein 839557..842112 Bifidobacterium animalis subsp. lactis DSM 10140 8010333 YP_002969714.1 CDS Balat_0712 NC_012815.1 842195 842914 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter complement(842195..842914) Bifidobacterium animalis subsp. lactis DSM 10140 8010334 YP_002969715.1 CDS Balat_0713 NC_012815.1 842952 844289 R COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein complement(842952..844289) Bifidobacterium animalis subsp. lactis DSM 10140 8010335 YP_002969716.1 CDS Balat_0714 NC_012815.1 844386 844646 R transporter complement(844386..844646) Bifidobacterium animalis subsp. lactis DSM 10140 8010336 YP_002969717.1 CDS Balat_0715 NC_012815.1 844774 845679 D COG0566 rRNA methylases; rRNA methylase 844774..845679 Bifidobacterium animalis subsp. lactis DSM 10140 8010337 YP_002969718.1 CDS pheS NC_012815.1 845758 846825 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 845758..846825 Bifidobacterium animalis subsp. lactis DSM 10140 8010338 YP_002969719.1 CDS pheT NC_012815.1 846845 849436 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 846845..849436 Bifidobacterium animalis subsp. lactis DSM 10140 8010339 YP_002969720.1 CDS Balat_0718 NC_012815.1 849476 850264 D hypothetical protein 849476..850264 Bifidobacterium animalis subsp. lactis DSM 10140 8010340 YP_002969721.1 CDS argC NC_012815.1 850393 851487 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 850393..851487 Bifidobacterium animalis subsp. lactis DSM 10140 8010341 YP_002969722.1 CDS argJ NC_012815.1 851484 852656 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 851484..852656 Bifidobacterium animalis subsp. lactis DSM 10140 8010342 YP_002969723.1 CDS Balat_0721 NC_012815.1 852666 853622 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 852666..853622 Bifidobacterium animalis subsp. lactis DSM 10140 8010343 YP_002969724.1 CDS argD NC_012815.1 853612 854865 D catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 853612..854865 Bifidobacterium animalis subsp. lactis DSM 10140 8010344 YP_002969725.1 CDS Balat_0723 NC_012815.1 854949 855911 D catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 854949..855911 Bifidobacterium animalis subsp. lactis DSM 10140 8010345 YP_002969726.1 CDS Balat_0724 NC_012815.1 855931 856476 D COG1438 Arginine repressor; arginine repressor ArgR 855931..856476 Bifidobacterium animalis subsp. lactis DSM 10140 8010346 YP_002969727.1 CDS Balat_0725 NC_012815.1 856556 857794 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 856556..857794 Bifidobacterium animalis subsp. lactis DSM 10140 8010347 YP_002969728.1 CDS Balat_0726 NC_012815.1 857909 859405 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 857909..859405 Bifidobacterium animalis subsp. lactis DSM 10140 8010348 YP_002969729.1 CDS Balat_0727 NC_012815.1 859489 860274 R COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); L-2,3-butanediol dehydrogenase/acetoinreductase complement(859489..860274) Bifidobacterium animalis subsp. lactis DSM 10140 8010349 YP_002969730.1 CDS Balat_0728 NC_012815.1 860327 860914 D COG1418 Predicted HD superfamily hydrolase; hypothetical protein 860327..860914 Bifidobacterium animalis subsp. lactis DSM 10140 8010350 YP_002969731.1 CDS Balat_0729 NC_012815.1 861003 862325 D COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 861003..862325 Bifidobacterium animalis subsp. lactis DSM 10140 8010351 YP_002969732.1 CDS Balat_0730 NC_012815.1 862461 864128 D hypothetical protein 862461..864128 Bifidobacterium animalis subsp. lactis DSM 10140 8010352 YP_002969733.1 CDS Balat_0731 NC_012815.1 864125 865165 D COG0647 Predicted sugar phosphatases of the HAD superfamily; hypothetical protein 864125..865165 Bifidobacterium animalis subsp. lactis DSM 10140 8010353 YP_002969734.1 CDS Balat_0732 NC_012815.1 865225 865983 D COG1189 Predicted rRNA methylase; hemolysin-like protein 865225..865983 Bifidobacterium animalis subsp. lactis DSM 10140 8010354 YP_002969735.1 CDS Balat_0733 NC_012815.1 866241 867704 D COG0168 Trk-type K+ transport systems, membrane components; hypothetical protein 866241..867704 Bifidobacterium animalis subsp. lactis DSM 10140 8010355 YP_002969736.1 CDS Balat_0734 NC_012815.1 867795 868445 D COG0569 K+ transport systems, NAD-binding component; hypothetical protein 867795..868445 Bifidobacterium animalis subsp. lactis DSM 10140 8010356 YP_002969737.1 CDS ppnK NC_012815.1 868535 869509 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 868535..869509 Bifidobacterium animalis subsp. lactis DSM 10140 8010357 YP_002969738.1 CDS recN NC_012815.1 869634 871364 D COG0497 ATPase involved in DNA repair; DNA repair protein RecN 869634..871364 Bifidobacterium animalis subsp. lactis DSM 10140 8010358 YP_002969739.1 CDS Balat_0737 NC_012815.1 871376 872059 D COG0637 Predicted phosphatase/phosphohexomutase; hydrolyase 871376..872059 Bifidobacterium animalis subsp. lactis DSM 10140 8010359 YP_002969740.1 CDS Balat_0738 NC_012815.1 872153 873640 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(872153..873640) Bifidobacterium animalis subsp. lactis DSM 10140 8010360 YP_002969741.1 CDS proA NC_012815.1 873777 875090 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 873777..875090 Bifidobacterium animalis subsp. lactis DSM 10140 8010361 YP_002969742.1 CDS Balat_0740 NC_012815.1 875108 875725 D hypothetical protein 875108..875725 Bifidobacterium animalis subsp. lactis DSM 10140 8010362 YP_002969743.1 CDS nadD NC_012815.1 875722 876426 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 875722..876426 Bifidobacterium animalis subsp. lactis DSM 10140 8010363 YP_002969744.1 CDS Balat_0742 NC_012815.1 876518 877537 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 876518..877537 Bifidobacterium animalis subsp. lactis DSM 10140 8010364 YP_002969745.1 CDS glmU NC_012815.1 877761 879143 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 877761..879143 Bifidobacterium animalis subsp. lactis DSM 10140 8010366 YP_002969746.1 CDS Balat_0745 NC_012815.1 879154 879558 D COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 879154..879558 Bifidobacterium animalis subsp. lactis DSM 10140 8010367 YP_002969747.1 CDS Balat_0746 NC_012815.1 879622 880254 D COG0406 Fructose-2,6-bisphosphatase; hypothetical protein 879622..880254 Bifidobacterium animalis subsp. lactis DSM 10140 8010368 YP_002969748.1 CDS Balat_0747 NC_012815.1 880354 881283 D hypothetical protein 880354..881283 Bifidobacterium animalis subsp. lactis DSM 10140 8010369 YP_002969749.1 CDS Balat_0750 NC_012815.1 881633 882037 D COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase; hypothetical protein 881633..882037 Bifidobacterium animalis subsp. lactis DSM 10140 8010371 YP_002969750.1 CDS Balat_0751 NC_012815.1 882136 882960 D COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 882136..882960 Bifidobacterium animalis subsp. lactis DSM 10140 8010372 YP_002969751.1 CDS Balat_0752 NC_012815.1 883101 884051 D COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter 883101..884051 Bifidobacterium animalis subsp. lactis DSM 10140 8010373 YP_002969752.1 CDS Balat_0753 NC_012815.1 884180 884950 D COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; solute binding protein of ABC transporter system 884180..884950 Bifidobacterium animalis subsp. lactis DSM 10140 8010374 YP_002969753.1 CDS leuS NC_012815.1 885111 888002 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 885111..888002 Bifidobacterium animalis subsp. lactis DSM 10140 8010375 YP_002969754.1 CDS Balat_0755 NC_012815.1 888114 888890 D COG1555 DNA uptake protein and related DNA-binding proteins; putative DNA-binding protein 888114..888890 Bifidobacterium animalis subsp. lactis DSM 10140 8010376 YP_002969755.1 CDS Balat_0756 NC_012815.1 888872 890638 D COG0658 Predicted membrane metal-binding protein; putative transmembrane protein related to ComA 888872..890638 Bifidobacterium animalis subsp. lactis DSM 10140 8010377 YP_002969756.1 CDS Balat_0757 NC_012815.1 890704 891666 D COG1466 DNA polymerase III, delta subunit; hypothetical protein 890704..891666 Bifidobacterium animalis subsp. lactis DSM 10140 8010378 YP_002969757.1 CDS Balat_0758 NC_012815.1 891663 892292 D COG0802 Predicted ATPase or kinase; putative ATPase 891663..892292 Bifidobacterium animalis subsp. lactis DSM 10140 8010379 YP_002969758.1 CDS Balat_0759 NC_012815.1 892368 893210 D COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; hypothetical protein 892368..893210 Bifidobacterium animalis subsp. lactis DSM 10140 8010380 YP_002969759.1 CDS Balat_0760 NC_012815.1 893207 893704 D COG0456 Acetyltransferases; Acetyltransferase 893207..893704 Bifidobacterium animalis subsp. lactis DSM 10140 8010381 YP_002969760.1 CDS Balat_0761 NC_012815.1 893745 894788 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 893745..894788 Bifidobacterium animalis subsp. lactis DSM 10140 8010382 YP_002969761.1 CDS Balat_0763 NC_012815.1 895021 895527 R hypothetical protein complement(895021..895527) Bifidobacterium animalis subsp. lactis DSM 10140 8010384 YP_002969762.1 CDS Balat_0765 NC_012815.1 895857 896234 D hypothetical protein 895857..896234 Bifidobacterium animalis subsp. lactis DSM 10140 8010386 YP_002969763.1 CDS Balat_0766 NC_012815.1 896469 897047 D COG0739 Membrane proteins related to metalloendopeptidases; hypothetical protein 896469..897047 Bifidobacterium animalis subsp. lactis DSM 10140 8010387 YP_002969764.1 CDS Balat_0767 NC_012815.1 897068 898582 R COG4213 ABC-type xylose transport system, periplasmic component; hypothetical protein complement(897068..898582) Bifidobacterium animalis subsp. lactis DSM 10140 8010388 YP_002969765.1 CDS Balat_0768 NC_012815.1 898698 899921 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(898698..899921) Bifidobacterium animalis subsp. lactis DSM 10140 8010389 YP_002969766.1 CDS Balat_0769 NC_012815.1 900048 901169 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 900048..901169 Bifidobacterium animalis subsp. lactis DSM 10140 8010390 YP_002969767.1 CDS Balat_0770 NC_012815.1 901385 901966 D hypothetical protein 901385..901966 Bifidobacterium animalis subsp. lactis DSM 10140 8010391 YP_002969768.1 CDS Balat_0771 NC_012815.1 902015 904090 D COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty acid CoA ligase 902015..904090 Bifidobacterium animalis subsp. lactis DSM 10140 8010392 YP_002969769.1 CDS Balat_0772 NC_012815.1 904096 904578 D COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase 904096..904578 Bifidobacterium animalis subsp. lactis DSM 10140 8010393 YP_002969770.1 CDS rpsB NC_012815.1 904855 905766 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 904855..905766 Bifidobacterium animalis subsp. lactis DSM 10140 8010394 YP_002969771.1 CDS tsf NC_012815.1 905876 906733 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 905876..906733 Bifidobacterium animalis subsp. lactis DSM 10140 8010395 YP_002969772.1 CDS pyrH NC_012815.1 906877 907623 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 906877..907623 Bifidobacterium animalis subsp. lactis DSM 10140 8010396 YP_002969773.1 CDS frr NC_012815.1 907708 908229 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 907708..908229 Bifidobacterium animalis subsp. lactis DSM 10140 8010397 YP_002969774.1 CDS Balat_0777 NC_012815.1 908322 909290 D COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase 908322..909290 Bifidobacterium animalis subsp. lactis DSM 10140 8010398 YP_002969775.1 CDS Balat_0778 NC_012815.1 909304 910500 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 909304..910500 Bifidobacterium animalis subsp. lactis DSM 10140 8010399 YP_002969776.1 CDS Balat_0779 NC_012815.1 910620 911189 D COG1309 Transcriptional regulator; hypothetical protein 910620..911189 Bifidobacterium animalis subsp. lactis DSM 10140 8010400 YP_002969777.1 CDS Balat_0780 NC_012815.1 911290 911925 D COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATPase 911290..911925 Bifidobacterium animalis subsp. lactis DSM 10140 8010401 YP_002969778.1 CDS Balat_0781 NC_012815.1 911933 912670 D COG0842 ABC-type multidrug transport system, permease component; hypothetical protein 911933..912670 Bifidobacterium animalis subsp. lactis DSM 10140 8010402 YP_002969779.1 CDS Balat_0782 NC_012815.1 912812 913582 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 912812..913582 Bifidobacterium animalis subsp. lactis DSM 10140 8010403 YP_002969780.1 CDS hisI NC_012815.1 913654 914067 D PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 913654..914067 Bifidobacterium animalis subsp. lactis DSM 10140 8010404 YP_002969781.1 CDS Balat_0784 NC_012815.1 914064 915629 D COG0147 Anthranilate/para-aminobenzoate synthases component I; Anthranilate/para-aminobenzoate synthases component I 914064..915629 Bifidobacterium animalis subsp. lactis DSM 10140 8010405 YP_002969782.1 CDS Balat_0785 NC_012815.1 915709 916299 R COG1573 Uracil-DNA glycosylase; uracil-DNA glycosylase complement(915709..916299) Bifidobacterium animalis subsp. lactis DSM 10140 8010406 YP_002969783.1 CDS Balat_0786 NC_012815.1 916479 916628 R hypothetical protein complement(916479..916628) Bifidobacterium animalis subsp. lactis DSM 10140 8010407 YP_002969784.1 CDS Balat_0787 NC_012815.1 916835 917140 R hypothetical protein complement(916835..917140) Bifidobacterium animalis subsp. lactis DSM 10140 8010408 YP_002969785.1 CDS Balat_0788 NC_012815.1 917391 919475 D catalyzes ring closure to form indole-3-glycerol phosphate; catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta 917391..919475 Bifidobacterium animalis subsp. lactis DSM 10140 8010409 YP_002969786.1 CDS trpA NC_012815.1 919501 920370 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 919501..920370 Bifidobacterium animalis subsp. lactis DSM 10140 8010410 YP_002969787.1 CDS Balat_0790 NC_012815.1 920467 921405 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 920467..921405 Bifidobacterium animalis subsp. lactis DSM 10140 8010411 YP_002969788.1 CDS Balat_0791 NC_012815.1 921460 922125 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 921460..922125 Bifidobacterium animalis subsp. lactis DSM 10140 8010412 YP_002969789.1 CDS hisE NC_012815.1 922222 922485 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 922222..922485 Bifidobacterium animalis subsp. lactis DSM 10140 8010413 YP_002969790.1 CDS hisG NC_012815.1 922549 923400 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 922549..923400 Bifidobacterium animalis subsp. lactis DSM 10140 8010414 YP_002969791.1 CDS Balat_0794 NC_012815.1 923421 924047 D COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3- phosphate3-phosphatidyl-transferase 923421..924047 Bifidobacterium animalis subsp. lactis DSM 10140 8010415 YP_002969792.1 CDS Balat_0795 NC_012815.1 924207 925049 D COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 924207..925049 Bifidobacterium animalis subsp. lactis DSM 10140 8010416 YP_002969793.1 CDS Balat_0796 NC_012815.1 925049 925381 D COG3856 Uncharacterized conserved protein (small basic protein); hypothetical protein 925049..925381 Bifidobacterium animalis subsp. lactis DSM 10140 8010417 YP_002969794.1 CDS Balat_0797 NC_012815.1 925384 926262 D COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 925384..926262 Bifidobacterium animalis subsp. lactis DSM 10140 8010418 YP_002969795.1 CDS Balat_0798 NC_012815.1 926269 926709 D COG1716 FOG: FHA domain; hypothetical protein 926269..926709 Bifidobacterium animalis subsp. lactis DSM 10140 8010419 YP_002969796.1 CDS Balat_0799 NC_012815.1 926732 927463 D COG0789 Predicted transcriptional regulators; SoxR-type transcriptional regulator 926732..927463 Bifidobacterium animalis subsp. lactis DSM 10140 8010420 YP_002969797.1 CDS Balat_0800 NC_012815.1 927548 927901 D hypothetical protein 927548..927901 Bifidobacterium animalis subsp. lactis DSM 10140 8010421 YP_002969798.1 CDS Balat_0801 NC_012815.1 927898 928275 D COG0239 Integral membrane protein possibly involved in chromosome condensation; CrcB protein 927898..928275 Bifidobacterium animalis subsp. lactis DSM 10140 8010422 YP_002969799.1 CDS Balat_0802 NC_012815.1 928287 928664 D COG0239 Integral membrane protein possibly involved in chromosome condensation; hypothetical protein 928287..928664 Bifidobacterium animalis subsp. lactis DSM 10140 8010423 YP_002969800.1 CDS Balat_0803 NC_012815.1 929217 929936 R COG0546 Predicted phosphatases; hydrolase or phosphatase complement(929217..929936) Bifidobacterium animalis subsp. lactis DSM 10140 8010424 YP_002969801.1 CDS Balat_0804 NC_012815.1 930024 930371 R hypothetical protein complement(930024..930371) Bifidobacterium animalis subsp. lactis DSM 10140 8010425 YP_002969802.1 CDS Balat_0805 NC_012815.1 930476 932965 R COG4581 Superfamily II RNA helicase; helicase complement(930476..932965) Bifidobacterium animalis subsp. lactis DSM 10140 8010426 YP_002969803.1 CDS Balat_0806 NC_012815.1 933082 933399 R hypothetical protein complement(933082..933399) Bifidobacterium animalis subsp. lactis DSM 10140 8010427 YP_002969804.1 CDS Balat_0807 NC_012815.1 933489 935426 R COG2378 Predicted transcriptional regulator; hypothetical protein complement(933489..935426) Bifidobacterium animalis subsp. lactis DSM 10140 8010428 YP_002969805.1 CDS Balat_0808 NC_012815.1 935563 936990 R COG4284 UDP-glucose pyrophosphorylase; UTP-glucose-1-phosphate uridylyltransferase complement(935563..936990) Bifidobacterium animalis subsp. lactis DSM 10140 8010429 YP_002969806.1 CDS Balat_0810 NC_012815.1 937409 939541 R CMK catalyzes the formation of (d)CDP from ATP and (d)CMP; the function of the GTP-binding domain EngA appears to be in synchronizing cellular events by interacting with multiple cellular targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide-binding affinities in the two binding domains; bifunctional cytidylate kinase/GTP-binding protein complement(937409..939541) Bifidobacterium animalis subsp. lactis DSM 10140 8010431 YP_002969807.1 CDS Balat_0811 NC_012815.1 939538 940311 R COG1187 16S rRNA uridine-516 pseudo uridylatesynthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudo uridylate synthase complement(939538..940311) Bifidobacterium animalis subsp. lactis DSM 10140 8010432 YP_002969808.1 CDS Balat_0812 NC_012815.1 940467 941489 D COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); membrane channel protein 940467..941489 Bifidobacterium animalis subsp. lactis DSM 10140 8010433 YP_002969809.1 CDS Balat_0813 NC_012815.1 941403 941693 R hypothetical protein complement(941403..941693) Bifidobacterium animalis subsp. lactis DSM 10140 8010434 YP_002969810.1 CDS purH NC_012815.1 941848 943497 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(941848..943497) Bifidobacterium animalis subsp. lactis DSM 10140 8010435 YP_002969811.1 CDS Balat_0815 NC_012815.1 943487 944845 R hypothetical protein complement(943487..944845) Bifidobacterium animalis subsp. lactis DSM 10140 8010436 YP_002969812.1 CDS Balat_0816 NC_012815.1 944845 945762 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(944845..945762) Bifidobacterium animalis subsp. lactis DSM 10140 8010437 YP_002969813.1 CDS Balat_0817 NC_012815.1 945763 946956 R COG0045 Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase subunit beta complement(945763..946956) Bifidobacterium animalis subsp. lactis DSM 10140 8010438 YP_002969814.1 CDS Balat_0818 NC_012815.1 946978 947559 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(946978..947559) Bifidobacterium animalis subsp. lactis DSM 10140 8010439 YP_002969815.1 CDS Balat_0819 NC_012815.1 947603 948043 R COG1862 Preprotein translocase subunit YajC; hypothetical protein complement(947603..948043) Bifidobacterium animalis subsp. lactis DSM 10140 8010440 YP_002969816.1 CDS ruvB NC_012815.1 948097 949164 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(948097..949164) Bifidobacterium animalis subsp. lactis DSM 10140 8010441 YP_002969817.1 CDS Balat_0821 NC_012815.1 949192 949815 R COG0632 Holliday junction resolvasome, DNA-binding subunit; holliday junction ATP-dependent DNA helicase ruvA complement(949192..949815) Bifidobacterium animalis subsp. lactis DSM 10140 8010442 YP_002969818.1 CDS ruvC NC_012815.1 949853 950434 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(949853..950434) Bifidobacterium animalis subsp. lactis DSM 10140 8010443 YP_002969819.1 CDS Balat_0823 NC_012815.1 950441 951196 R COG0217 Uncharacterized conserved protein; hypothetical protein complement(950441..951196) Bifidobacterium animalis subsp. lactis DSM 10140 8010444 YP_002969820.1 CDS Balat_0824 NC_012815.1 951250 952419 R COG0438 Glycosyltransferase; glycosyltransferase complement(951250..952419) Bifidobacterium animalis subsp. lactis DSM 10140 8010445 YP_002969821.1 CDS Balat_0825 NC_012815.1 952479 953474 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(952479..953474) Bifidobacterium animalis subsp. lactis DSM 10140 8010446 YP_002969822.1 CDS Balat_0826 NC_012815.1 953536 954207 R COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate3- phosphatidyltransferase complement(953536..954207) Bifidobacterium animalis subsp. lactis DSM 10140 8010447 YP_002969823.1 CDS thrS NC_012815.1 954366 956444 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(954366..956444) Bifidobacterium animalis subsp. lactis DSM 10140 8010448 YP_002969824.1 CDS Balat_0828 NC_012815.1 956661 957170 R COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein complement(956661..957170) Bifidobacterium animalis subsp. lactis DSM 10140 8010449 YP_002969825.1 CDS Balat_0830 NC_012815.1 957565 958086 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; transcriptional regulator 957565..958086 Bifidobacterium animalis subsp. lactis DSM 10140 8010451 YP_002969826.1 CDS Balat_0831 NC_012815.1 958132 958311 R hypothetical protein complement(958132..958311) Bifidobacterium animalis subsp. lactis DSM 10140 8010452 YP_002969827.1 CDS Balat_0832 NC_012815.1 958359 958721 R hypothetical protein complement(958359..958721) Bifidobacterium animalis subsp. lactis DSM 10140 8010453 YP_002969828.1 CDS Balat_0837 NC_012815.1 959978 960778 D hypothetical protein 959978..960778 Bifidobacterium animalis subsp. lactis DSM 10140 8010458 YP_002969829.1 CDS Balat_0838 NC_012815.1 960872 961759 R phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(960872..961759) Bifidobacterium animalis subsp. lactis DSM 10140 8010459 YP_002969830.1 CDS Balat_0839 NC_012815.1 961933 962727 D COG3001 Fructosamine-3-kinase; hypothetical protein 961933..962727 Bifidobacterium animalis subsp. lactis DSM 10140 8010460 YP_002969831.1 CDS dnaJ NC_012815.1 962850 963998 R COG0484 DnaJ-class molecular chaperone withC-terminal Zn finger domain; DnaJ-class molecular chaperone complement(962850..963998) Bifidobacterium animalis subsp. lactis DSM 10140 8010461 YP_002969832.1 CDS hrcA NC_012815.1 964067 965167 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(964067..965167) Bifidobacterium animalis subsp. lactis DSM 10140 8010462 YP_002969833.1 CDS Balat_0842 NC_012815.1 965384 967480 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 965384..967480 Bifidobacterium animalis subsp. lactis DSM 10140 8010463 YP_002969834.1 CDS Balat_0843 NC_012815.1 967576 968682 D catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 967576..968682 Bifidobacterium animalis subsp. lactis DSM 10140 8010464 YP_002969835.1 CDS Balat_0844 NC_012815.1 968770 969435 R COG1357 Uncharacterized low-complexity proteins; hypothetical protein complement(968770..969435) Bifidobacterium animalis subsp. lactis DSM 10140 8010465 YP_002969836.1 CDS Balat_0845 NC_012815.1 969419 970618 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; class I and II aminotransferase complement(969419..970618) Bifidobacterium animalis subsp. lactis DSM 10140 8010466 YP_002969837.1 CDS Balat_0846 NC_012815.1 970618 971136 R COG1522 Transcriptional regulators; AsnC family transcriptional regulator complement(970618..971136) Bifidobacterium animalis subsp. lactis DSM 10140 8010467 YP_002969838.1 CDS Balat_0847 NC_012815.1 971190 972869 R in Corynebacterium glutamicum the aminotransferase can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; this protein contains a helix-turn-helix domain at the N-terminus; bifunctional HTH-domain containing protein/aminotransferase complement(971190..972869) Bifidobacterium animalis subsp. lactis DSM 10140 8010468 YP_002969839.1 CDS Balat_0848 NC_012815.1 972980 973810 R COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein complement(972980..973810) Bifidobacterium animalis subsp. lactis DSM 10140 8010469 YP_002969840.1 CDS secG NC_012815.1 973910 974158 R preprotein translocase subunit SecG complement(973910..974158) Bifidobacterium animalis subsp. lactis DSM 10140 8010470 YP_002969841.1 CDS tpiA NC_012815.1 974225 975037 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(974225..975037) Bifidobacterium animalis subsp. lactis DSM 10140 8010471 YP_002969842.1 CDS pgk NC_012815.1 975131 976336 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(975131..976336) Bifidobacterium animalis subsp. lactis DSM 10140 8010472 YP_002969843.1 CDS Balat_0852 NC_012815.1 976458 977420 R COG1481 Uncharacterized protein conserved in bacteria; hypothetical protein complement(976458..977420) Bifidobacterium animalis subsp. lactis DSM 10140 8010473 YP_002969844.1 CDS Balat_0853 NC_012815.1 977569 978501 R COG1660 Predicted P-loop-containing kinase; hypothetical protein complement(977569..978501) Bifidobacterium animalis subsp. lactis DSM 10140 8010474 YP_002969845.1 CDS Balat_0854 NC_012815.1 978501 979427 R COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase complement(978501..979427) Bifidobacterium animalis subsp. lactis DSM 10140 8010475 YP_002969846.1 CDS uvrC NC_012815.1 979558 981948 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(979558..981948) Bifidobacterium animalis subsp. lactis DSM 10140 8010476 YP_002969847.1 CDS uvrA NC_012815.1 982011 984971 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(982011..984971) Bifidobacterium animalis subsp. lactis DSM 10140 8010477 YP_002969848.1 CDS Balat_0857 NC_012815.1 985300 986265 D hypothetical protein 985300..986265 Bifidobacterium animalis subsp. lactis DSM 10140 8010478 YP_002969849.1 CDS Balat_0858 NC_012815.1 986351 986878 D COG3663 G:T/U mismatch-specific DNA glycosylase; G:T/U mismatch-specific DNA glycosylase 986351..986878 Bifidobacterium animalis subsp. lactis DSM 10140 8010479 YP_002969850.1 CDS Balat_0859 NC_012815.1 986935 987564 D COG0400 Predicted esterase; putative esterase 986935..987564 Bifidobacterium animalis subsp. lactis DSM 10140 8010480 YP_002969851.1 CDS Balat_0860 NC_012815.1 987554 989155 D COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 987554..989155 Bifidobacterium animalis subsp. lactis DSM 10140 8010481 YP_002969852.1 CDS Balat_0861 NC_012815.1 989264 990334 R COG0053 Predicted Co/Zn/Cd cation transporters; cation transporter complement(989264..990334) Bifidobacterium animalis subsp. lactis DSM 10140 8010482 YP_002969853.1 CDS Balat_0862 NC_012815.1 990385 991158 R COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; putative carboxymuconolactone decarboxylase complement(990385..991158) Bifidobacterium animalis subsp. lactis DSM 10140 8010483 YP_002969854.1 CDS bsh NC_012815.1 991279 992223 R COG3049 Penicillin V acylase and related amidases; bile salt hydrolase, choloylglycine hydrolase complement(991279..992223) Bifidobacterium animalis subsp. lactis DSM 10140 8010484 YP_002969855.1 CDS Balat_0864 NC_012815.1 992434 994245 D COG0062 Uncharacterized conserved protein; hypothetical protein 992434..994245 Bifidobacterium animalis subsp. lactis DSM 10140 8010485 YP_002969856.1 CDS Balat_0865 NC_012815.1 994381 994938 D COG0450 Peroxiredoxin; Peroxiredoxin 994381..994938 Bifidobacterium animalis subsp. lactis DSM 10140 8010486 YP_002969857.1 CDS Balat_0866 NC_012815.1 994957 996729 D COG0492 Thioredoxin reductase; thioredoxin reductase-like protein 994957..996729 Bifidobacterium animalis subsp. lactis DSM 10140 8010487 YP_002969858.1 CDS Balat_0867 NC_012815.1 996820 997746 R COG0583 Transcriptional regulator; fhu operon transcription regulator complement(996820..997746) Bifidobacterium animalis subsp. lactis DSM 10140 8010488 YP_002969859.1 CDS Balat_0868 NC_012815.1 997815 998471 R COG1011 Predicted hydrolase (HAD superfamily); alpha beta hydrolase complement(997815..998471) Bifidobacterium animalis subsp. lactis DSM 10140 8010489 YP_002969860.1 CDS Balat_0869 NC_012815.1 998625 999608 D COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 998625..999608 Bifidobacterium animalis subsp. lactis DSM 10140 8010490 YP_002969861.1 CDS Balat_0870 NC_012815.1 1000036 1000944 D COG1397 ADP-ribosylglycohydrolase; hydrolase 1000036..1000944 Bifidobacterium animalis subsp. lactis DSM 10140 8010491 YP_002969862.1 CDS Balat_0871 NC_012815.1 1001115 1001459 D COG1733 Predicted transcriptional regulators; transcriptional regulator 1001115..1001459 Bifidobacterium animalis subsp. lactis DSM 10140 8010492 YP_002969863.1 CDS Balat_0872 NC_012815.1 1001642 1002175 D hypothetical protein 1001642..1002175 Bifidobacterium animalis subsp. lactis DSM 10140 8010493 YP_002969864.1 CDS Balat_0873 NC_012815.1 1002182 1002607 R COG0456 Acetyltransferases; acetyltransferase complement(1002182..1002607) Bifidobacterium animalis subsp. lactis DSM 10140 8010494 YP_002969865.1 CDS pyrE NC_012815.1 1003103 1003798 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(1003103..1003798) Bifidobacterium animalis subsp. lactis DSM 10140 8010495 YP_002969866.1 CDS Balat_0875 NC_012815.1 1003936 1004919 R COG0167 Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase complement(1003936..1004919) Bifidobacterium animalis subsp. lactis DSM 10140 8010496 YP_002969867.1 CDS Balat_0876 NC_012815.1 1004912 1005751 R COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; dihydroorotate dehydrogenase electron transfer subunit complement(1004912..1005751) Bifidobacterium animalis subsp. lactis DSM 10140 8010497 YP_002969868.1 CDS Balat_0877 NC_012815.1 1005819 1006769 R COG0284 Orotidine-5-phosphate decarboxylase; orotidine 5-phosphate decarboxylase complement(1005819..1006769) Bifidobacterium animalis subsp. lactis DSM 10140 8010498 YP_002969869.1 CDS Balat_0878 NC_012815.1 1006775 1008199 R COG0044 Dihydroorotase and related cyclicamidohydrolases; dihydroorotase complement(1006775..1008199) Bifidobacterium animalis subsp. lactis DSM 10140 8010499 YP_002969870.1 CDS Balat_0879 NC_012815.1 1008200 1008619 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(1008200..1008619) Bifidobacterium animalis subsp. lactis DSM 10140 8010500 YP_002969871.1 CDS pyrB NC_012815.1 1008619 1009578 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(1008619..1009578) Bifidobacterium animalis subsp. lactis DSM 10140 8010501 YP_002969872.1 CDS Balat_0881 NC_012815.1 1009708 1010190 R hypothetical protein complement(1009708..1010190) Bifidobacterium animalis subsp. lactis DSM 10140 8010502 YP_002969873.1 CDS Balat_0882 NC_012815.1 1010206 1013340 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(1010206..1013340) Bifidobacterium animalis subsp. lactis DSM 10140 8010503 YP_002969874.1 CDS Balat_0883 NC_012815.1 1013383 1014219 R COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase complement(1013383..1014219) Bifidobacterium animalis subsp. lactis DSM 10140 8010504 YP_002969875.1 CDS Balat_0884 NC_012815.1 1014366 1016669 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase complement(1014366..1016669) Bifidobacterium animalis subsp. lactis DSM 10140 8010505 YP_002969876.1 CDS Balat_0885 NC_012815.1 1016816 1017370 R COG2062 Phosphohistidine phosphatase SixA; hypothetical protein complement(1016816..1017370) Bifidobacterium animalis subsp. lactis DSM 10140 8010506 YP_002969877.1 CDS Balat_0886 NC_012815.1 1017471 1018529 R COG2519 tRNA (1-methyladenosine methyltransferase and related methyltransferases); hypothetical protein complement(1017471..1018529) Bifidobacterium animalis subsp. lactis DSM 10140 8010507 YP_002969878.1 CDS Balat_0887 NC_012815.1 1018627 1019469 R COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; ABC transporter ATP-binding protein complement(1018627..1019469) Bifidobacterium animalis subsp. lactis DSM 10140 8010508 YP_002969879.1 CDS Balat_0888 NC_012815.1 1019543 1020802 R COG0438 Glycosyltransferase; glycosyltransferase complement(1019543..1020802) Bifidobacterium animalis subsp. lactis DSM 10140 8010509 YP_002969880.1 CDS Balat_0889 NC_012815.1 1021039 1021524 D COG1225 Peroxiredoxin; thioredoxin peroxidase 1021039..1021524 Bifidobacterium animalis subsp. lactis DSM 10140 8010510 YP_002969881.1 CDS Balat_0890 NC_012815.1 1021608 1022066 R hypothetical protein complement(1021608..1022066) Bifidobacterium animalis subsp. lactis DSM 10140 8010511 YP_002969882.1 CDS gltD NC_012815.1 1022210 1023745 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta complement(1022210..1023745) Bifidobacterium animalis subsp. lactis DSM 10140 8010512 YP_002969883.1 CDS Balat_0892 NC_012815.1 1023747 1028267 R COG0067 Glutamate synthase domain 1; Glutamate synthase complement(1023747..1028267) Bifidobacterium animalis subsp. lactis DSM 10140 8010513 YP_002969884.1 CDS Balat_0893 NC_012815.1 1028540 1029853 R COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Coproporphyrinogen III oxidase complement(1028540..1029853) Bifidobacterium animalis subsp. lactis DSM 10140 8010514 YP_002969885.1 CDS Balat_0894 NC_012815.1 1029861 1031741 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1029861..1031741) Bifidobacterium animalis subsp. lactis DSM 10140 8010515 YP_002969886.1 CDS rpsT NC_012815.1 1031889 1032149 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1031889..1032149 Bifidobacterium animalis subsp. lactis DSM 10140 8010516 YP_002969887.1 CDS Balat_0896 NC_012815.1 1032240 1033025 R COG2860 Predicted membrane protein; hypothetical protein complement(1032240..1033025) Bifidobacterium animalis subsp. lactis DSM 10140 8010517 YP_002969888.1 CDS Balat_0897 NC_012815.1 1033145 1034272 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1033145..1034272) Bifidobacterium animalis subsp. lactis DSM 10140 8010518 YP_002969889.1 CDS Balat_0898 NC_012815.1 1034486 1035112 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1034486..1035112) Bifidobacterium animalis subsp. lactis DSM 10140 8010519 YP_002969890.1 CDS Balat_0899 NC_012815.1 1035358 1036359 D COG1073 Hydrolases of the alpha/beta superfamily; putative alpha/beta superfamily hydrolase 1035358..1036359 Bifidobacterium animalis subsp. lactis DSM 10140 8010520 YP_002969891.1 CDS Balat_0900 NC_012815.1 1036469 1037884 R COG1282 NAD/NADP transhydrogenase beta subunit; NAD/NADP transhydrogenase subunit beta complement(1036469..1037884) Bifidobacterium animalis subsp. lactis DSM 10140 8010521 YP_002969892.1 CDS Balat_0901 NC_012815.1 1037884 1038201 R COG3288 NAD/NADP transhydrogenase alpha subunit; NAD/NADP transhydrogenase subunit alpha complement(1037884..1038201) Bifidobacterium animalis subsp. lactis DSM 10140 8010522 YP_002969893.1 CDS Balat_0902 NC_012815.1 1038198 1039352 R COG3288 NAD/NADP transhydrogenase alpha subunit; NAD(P) transhydrogenase subunit alpha part 1 complement(1038198..1039352) Bifidobacterium animalis subsp. lactis DSM 10140 8010523 YP_002969894.1 CDS Balat_0903 NC_012815.1 1039619 1040128 D COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty-acid-CoA ligase 1039619..1040128 Bifidobacterium animalis subsp. lactis DSM 10140 8010524 YP_002969895.1 CDS era NC_012815.1 1041752 1042747 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(1041752..1042747) Bifidobacterium animalis subsp. lactis DSM 10140 8010525 YP_002969896.1 CDS Balat_0905 NC_012815.1 1042749 1044137 R COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein complement(1042749..1044137) Bifidobacterium animalis subsp. lactis DSM 10140 8010526 YP_002969897.1 CDS Balat_0906 NC_012815.1 1044155 1044700 R COG0319 Predicted metal-dependent hydrolase; putative metalloprotease complement(1044155..1044700) Bifidobacterium animalis subsp. lactis DSM 10140 8010527 YP_002969898.1 CDS Balat_0907 NC_012815.1 1044690 1045853 R COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; PhoH-like protein complement(1044690..1045853) Bifidobacterium animalis subsp. lactis DSM 10140 8010528 YP_002969899.1 CDS Balat_0908 NC_012815.1 1045908 1046243 R COG0537 Diadenosine tetraphosphate (Ap4A hydrolase and other HIT family hydrolases); hypothetical protein complement(1045908..1046243) Bifidobacterium animalis subsp. lactis DSM 10140 8010529 YP_002969900.1 CDS Balat_0909 NC_012815.1 1046335 1047132 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1046335..1047132) Bifidobacterium animalis subsp. lactis DSM 10140 8010530 YP_002969901.1 CDS Balat_0911 NC_012815.1 1047418 1048290 D COG0566 rRNA methylases; tRNA/rRNA methyltransferase 1047418..1048290 Bifidobacterium animalis subsp. lactis DSM 10140 8010532 YP_002969902.1 CDS Balat_0912 NC_012815.1 1048385 1049047 R transposase complement(1048385..1049047) Bifidobacterium animalis subsp. lactis DSM 10140 8010533 YP_002969903.1 CDS glgC NC_012815.1 1049314 1050561 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1049314..1050561 Bifidobacterium animalis subsp. lactis DSM 10140 8010534 YP_002969904.1 CDS Balat_0914 NC_012815.1 1050639 1051211 R COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; hypothetical protein complement(1050639..1051211) Bifidobacterium animalis subsp. lactis DSM 10140 8010535 YP_002969905.1 CDS Balat_0915 NC_012815.1 1051213 1051788 R COG0822 NifU homolog involved in Fe-S cluster formation; hypothetical protein complement(1051213..1051788) Bifidobacterium animalis subsp. lactis DSM 10140 8010536 YP_002969906.1 CDS Balat_0916 NC_012815.1 1051878 1053149 R COG0520 Selenocysteine lyase; NifS-like aminotransferase complement(1051878..1053149) Bifidobacterium animalis subsp. lactis DSM 10140 8010537 YP_002969907.1 CDS Balat_0917 NC_012815.1 1053180 1053959 R COG0396 ABC-type transport system involved in Fe-Scluster assembly, ATPase component; ABC transporter ATP-binding protein complement(1053180..1053959) Bifidobacterium animalis subsp. lactis DSM 10140 8010538 YP_002969908.1 CDS Balat_0918 NC_012815.1 1053959 1055185 R COG0719 ABC-type transport system involved in Fe-Scluster assembly, permease component; ABC-type transport system for Fe-S cluster assembly permease complement(1053959..1055185) Bifidobacterium animalis subsp. lactis DSM 10140 8010539 YP_002969909.1 CDS Balat_0919 NC_012815.1 1055189 1056685 R COG0719 ABC-type transport system involved in Fe-Scluster assembly, permease component; ABC-type transport system for Fe-S cluster assembly permease complement(1055189..1056685) Bifidobacterium animalis subsp. lactis DSM 10140 8010540 YP_002969910.1 CDS Balat_0920 NC_012815.1 1056892 1058559 R COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1056892..1058559) Bifidobacterium animalis subsp. lactis DSM 10140 8010541 YP_002969911.1 CDS Balat_0921 NC_012815.1 1058556 1058657 R hypothetical protein complement(1058556..1058657) Bifidobacterium animalis subsp. lactis DSM 10140 8010542 YP_002969912.1 CDS pyrG NC_012815.1 1058705 1060252 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1058705..1060252) Bifidobacterium animalis subsp. lactis DSM 10140 8010543 YP_002969913.1 CDS Balat_0923 NC_012815.1 1060518 1061066 R hypothetical protein complement(1060518..1061066) Bifidobacterium animalis subsp. lactis DSM 10140 8010544 YP_002969914.1 CDS Balat_0924 NC_012815.1 1061112 1062092 R COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; pullulanase complement(1061112..1062092) Bifidobacterium animalis subsp. lactis DSM 10140 8010545 YP_002969915.1 CDS Balat_0925 NC_012815.1 1063195 1063365 D hypothetical protein 1063195..1063365 Bifidobacterium animalis subsp. lactis DSM 10140 8010546 YP_002969916.1 CDS Balat_0926 NC_012815.1 1063389 1063505 R hypothetical protein complement(1063389..1063505) Bifidobacterium animalis subsp. lactis DSM 10140 8010547 YP_002969917.1 CDS Balat_0927 NC_012815.1 1063806 1064495 R hypothetical protein complement(1063806..1064495) Bifidobacterium animalis subsp. lactis DSM 10140 8010548 YP_002969918.1 CDS Balat_0928 NC_012815.1 1064513 1065715 R hypothetical protein complement(1064513..1065715) Bifidobacterium animalis subsp. lactis DSM 10140 8010549 YP_002969919.1 CDS Balat_0929 NC_012815.1 1065750 1066919 R hypothetical protein complement(1065750..1066919) Bifidobacterium animalis subsp. lactis DSM 10140 8010550 YP_002969920.1 CDS Balat_0930 NC_012815.1 1067087 1067512 D hypothetical protein 1067087..1067512 Bifidobacterium animalis subsp. lactis DSM 10140 8010551 YP_002969921.1 CDS Balat_0931 NC_012815.1 1067817 1068269 D hypothetical protein 1067817..1068269 Bifidobacterium animalis subsp. lactis DSM 10140 8010552 YP_002969922.1 CDS Balat_0932 NC_012815.1 1068310 1069275 D hypothetical protein 1068310..1069275 Bifidobacterium animalis subsp. lactis DSM 10140 8010553 YP_002969923.1 CDS Balat_0933 NC_012815.1 1069397 1069861 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(1069397..1069861) Bifidobacterium animalis subsp. lactis DSM 10140 8010554 YP_002969924.1 CDS aroB NC_012815.1 1069987 1071642 R catalyzes the formation of shikimate 3-phosphate from shikimate and the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; bifunctional shikimate kinase/3-dehydroquinate synthase complement(1069987..1071642) Bifidobacterium animalis subsp. lactis DSM 10140 8010555 YP_002969925.1 CDS Balat_0935 NC_012815.1 1071656 1072846 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(1071656..1072846) Bifidobacterium animalis subsp. lactis DSM 10140 8010556 YP_002969926.1 CDS Balat_0936 NC_012815.1 1072918 1073376 D hypothetical protein 1072918..1073376 Bifidobacterium animalis subsp. lactis DSM 10140 8010557 YP_002969927.1 CDS Balat_0937 NC_012815.1 1073427 1074608 R COG1559 Predicted periplasmic solute-binding protein; hypothetical protein complement(1073427..1074608) Bifidobacterium animalis subsp. lactis DSM 10140 8010558 YP_002969928.1 CDS Balat_0938 NC_012815.1 1074610 1075101 R COG0816 Predicted endonuclease involved inrecombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); putative endonuclease for recombination complement(1074610..1075101) Bifidobacterium animalis subsp. lactis DSM 10140 8010559 YP_002969929.1 CDS alaS NC_012815.1 1075101 1077800 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1075101..1077800) Bifidobacterium animalis subsp. lactis DSM 10140 8010560 YP_002969930.1 CDS Balat_0940 NC_012815.1 1077856 1078092 R hypothetical protein complement(1077856..1078092) Bifidobacterium animalis subsp. lactis DSM 10140 8010561 YP_002969931.1 CDS Balat_0941 NC_012815.1 1078092 1078493 R hypothetical protein complement(1078092..1078493) Bifidobacterium animalis subsp. lactis DSM 10140 8010562 YP_002969932.1 CDS Balat_0942 NC_012815.1 1078568 1079245 R COG0406 Fructose-2,6-bisphosphatase; hypothetical protein complement(1078568..1079245) Bifidobacterium animalis subsp. lactis DSM 10140 8010563 YP_002969933.1 CDS Balat_0943 NC_012815.1 1079319 1079684 D COG1950 Predicted membrane protein; hypothetical protein 1079319..1079684 Bifidobacterium animalis subsp. lactis DSM 10140 8010564 YP_002969934.1 CDS rpsD NC_012815.1 1079788 1080408 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1079788..1080408) Bifidobacterium animalis subsp. lactis DSM 10140 8010565 YP_002969935.1 CDS Balat_0945 NC_012815.1 1080638 1083457 R COG0210 Superfamily I DNA and RNA helicases; Superfamily I DNA and RNA helicase complement(1080638..1083457) Bifidobacterium animalis subsp. lactis DSM 10140 8010566 YP_002969936.1 CDS Balat_0946 NC_012815.1 1083539 1084120 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1083539..1084120 Bifidobacterium animalis subsp. lactis DSM 10140 8010567 YP_002969937.1 CDS Balat_0947 NC_012815.1 1084265 1085734 D COG2233 Xanthine/uracil permeases; Xanthine/uracil permease 1084265..1085734 Bifidobacterium animalis subsp. lactis DSM 10140 8010568 YP_002969938.1 CDS Balat_0948 NC_012815.1 1085941 1086786 D hypothetical protein 1085941..1086786 Bifidobacterium animalis subsp. lactis DSM 10140 8010569 YP_002969939.1 CDS Balat_0949 NC_012815.1 1086810 1087064 D COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; class II aminotransferase 1086810..1087064 Bifidobacterium animalis subsp. lactis DSM 10140 8010570 YP_002969940.1 CDS Balat_0950 NC_012815.1 1087054 1088004 D COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional beta-cystathionase/maltose regulonrepressor 1087054..1088004 Bifidobacterium animalis subsp. lactis DSM 10140 8010571 YP_002969941.1 CDS Balat_0951 NC_012815.1 1088001 1088858 R hypothetical protein complement(1088001..1088858) Bifidobacterium animalis subsp. lactis DSM 10140 8010572 YP_002969942.1 CDS Balat_0952 NC_012815.1 1089100 1090572 R COG0366 Glycosidases; cytoplasmic alpha-amylase complement(1089100..1090572) Bifidobacterium animalis subsp. lactis DSM 10140 8010573 YP_002969943.1 CDS Balat_0953 NC_012815.1 1090723 1091361 R COG2071 Predicted glutamine amidotransferases; amidotransferase subunit complement(1090723..1091361) Bifidobacterium animalis subsp. lactis DSM 10140 8010574 YP_002969944.1 CDS Balat_0954 NC_012815.1 1091601 1092080 R COG3760 Uncharacterized conserved protein; prolyl-tRNA synthetase complement(1091601..1092080) Bifidobacterium animalis subsp. lactis DSM 10140 8010575 YP_002969945.1 CDS Balat_0955 NC_012815.1 1092178 1092798 R hypothetical protein complement(1092178..1092798) Bifidobacterium animalis subsp. lactis DSM 10140 8010576 YP_002969946.1 CDS Balat_0956 NC_012815.1 1092795 1093673 R COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein complement(1092795..1093673) Bifidobacterium animalis subsp. lactis DSM 10140 8010577 YP_002969947.1 CDS Balat_0957 NC_012815.1 1093670 1094206 R COG1725 Predicted transcriptional regulators; hypothetical protein complement(1093670..1094206) Bifidobacterium animalis subsp. lactis DSM 10140 8010578 YP_002969948.1 CDS Balat_0958 NC_012815.1 1094431 1095438 D COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 1094431..1095438 Bifidobacterium animalis subsp. lactis DSM 10140 8010579 YP_002969949.1 CDS Balat_0959 NC_012815.1 1095506 1096531 D COG1816 Adenosine deaminase; adenosine deaminase 1095506..1096531 Bifidobacterium animalis subsp. lactis DSM 10140 8010580 YP_002969950.1 CDS Balat_0960 NC_012815.1 1096532 1097242 R putative cytoplasmic protein complement(1096532..1097242) Bifidobacterium animalis subsp. lactis DSM 10140 8010581 YP_002969951.1 CDS Balat_0961 NC_012815.1 1097528 1097833 D COG1605 Chorismate mutase; chorismate mutase 1097528..1097833 Bifidobacterium animalis subsp. lactis DSM 10140 8010582 YP_002969952.1 CDS Balat_0962 NC_012815.1 1098179 1098757 D hypothetical protein 1098179..1098757 Bifidobacterium animalis subsp. lactis DSM 10140 8010583 YP_002969953.1 CDS Balat_0963 NC_012815.1 1098770 1098991 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase complement(1098770..1098991) Bifidobacterium animalis subsp. lactis DSM 10140 8010584 YP_002969954.1 CDS Balat_0964 NC_012815.1 1099131 1099703 R COG0563 Adenylate kinase and related kinases; putative adenylate kinase DNA topology modulator complement(1099131..1099703) Bifidobacterium animalis subsp. lactis DSM 10140 8010585 YP_002969955.1 CDS Balat_0965 NC_012815.1 1099997 1100284 D COG1373 Predicted ATPase (AAA+ superfamily); hypothetical protein 1099997..1100284 Bifidobacterium animalis subsp. lactis DSM 10140 8010586 YP_002969956.1 CDS Balat_0966 NC_012815.1 1100454 1100549 D hypothetical protein 1100454..1100549 Bifidobacterium animalis subsp. lactis DSM 10140 8010587 YP_002969957.1 CDS Balat_0967 NC_012815.1 1100888 1102807 R COG0480 Translation elongation factors (GTPases); ribosomal protection tetracycline resistance protein complement(1100888..1102807) Bifidobacterium animalis subsp. lactis DSM 10140 8010588 YP_002969958.1 CDS Balat_0968 NC_012815.1 1103156 1104121 R COG3039 Transposase and inactivated derivatives, IS5 family; transposase, IS4 family protein complement(1103156..1104121) Bifidobacterium animalis subsp. lactis DSM 10140 8010589 YP_002969959.1 CDS Balat_0969 NC_012815.1 1104152 1104553 D COG0107 Imidazoleglycerol-phosphate synthase; hypothetical protein 1104152..1104553 Bifidobacterium animalis subsp. lactis DSM 10140 8010590 YP_002969960.1 CDS guaA NC_012815.1 1104749 1106311 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1104749..1106311) Bifidobacterium animalis subsp. lactis DSM 10140 8010591 YP_002969961.1 CDS Balat_0971 NC_012815.1 1106791 1109268 D COG3957 Phosphoketolase; putative phosphoketolase 1106791..1109268 Bifidobacterium animalis subsp. lactis DSM 10140 8010592 YP_002969962.1 CDS Balat_0972 NC_012815.1 1109509 1111191 D COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase 1109509..1111191 Bifidobacterium animalis subsp. lactis DSM 10140 8010593 YP_002969963.1 CDS Balat_0973 NC_012815.1 1111332 1112579 D COG0282 Acetate kinase; acetate kinase 1111332..1112579 Bifidobacterium animalis subsp. lactis DSM 10140 8010594 YP_002969964.1 CDS Balat_0974 NC_012815.1 1112654 1114000 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1112654..1114000) Bifidobacterium animalis subsp. lactis DSM 10140 8010595 YP_002969965.1 CDS Balat_0976 NC_012815.1 1114308 1115537 D hypothetical protein 1114308..1115537 Bifidobacterium animalis subsp. lactis DSM 10140 8010597 YP_002969966.1 CDS Balat_0977 NC_012815.1 1115600 1117717 R COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX complement(1115600..1117717) Bifidobacterium animalis subsp. lactis DSM 10140 8010598 YP_002969967.1 CDS Balat_0978 NC_012815.1 1117790 1118443 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase complement(1117790..1118443) Bifidobacterium animalis subsp. lactis DSM 10140 8010599 YP_002969968.1 CDS Balat_0979 NC_012815.1 1118447 1119382 R COG0327 Uncharacterized conserved protein; hypothetical protein complement(1118447..1119382) Bifidobacterium animalis subsp. lactis DSM 10140 8010600 YP_002969969.1 CDS Balat_0980 NC_012815.1 1119417 1122299 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1119417..1122299) Bifidobacterium animalis subsp. lactis DSM 10140 8010601 YP_002969970.1 CDS Balat_0981 NC_012815.1 1122379 1123137 R COG3707 Response regulator with putative antiterminator output domain; putative response regulator complement(1122379..1123137) Bifidobacterium animalis subsp. lactis DSM 10140 8010602 YP_002969971.1 CDS Balat_0982 NC_012815.1 1123270 1123899 R COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase complement(1123270..1123899) Bifidobacterium animalis subsp. lactis DSM 10140 8010603 YP_002969972.1 CDS Balat_0984 NC_012815.1 1124256 1125617 R COG0469 Pyruvate kinase; pyruvate kinase complement(1124256..1125617) Bifidobacterium animalis subsp. lactis DSM 10140 8010605 YP_002969973.1 CDS Balat_0985 NC_012815.1 1125866 1126855 R COG0861 Membrane protein TerC, possibly involved in tellurium resistance; membrane protein for putative tellurium resistance complement(1125866..1126855) Bifidobacterium animalis subsp. lactis DSM 10140 8010606 YP_002969974.1 CDS Balat_0986 NC_012815.1 1126918 1129029 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1126918..1129029) Bifidobacterium animalis subsp. lactis DSM 10140 8010607 YP_002969975.1 CDS Balat_0987 NC_012815.1 1129038 1129679 R COG0237 Dephospho-CoA kinase; dephospho-CoA kinase complement(1129038..1129679) Bifidobacterium animalis subsp. lactis DSM 10140 8010608 YP_002969976.1 CDS rpsA NC_012815.1 1129790 1131271 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1129790..1131271) Bifidobacterium animalis subsp. lactis DSM 10140 8010609 YP_002969977.1 CDS Balat_0989 NC_012815.1 1131443 1132336 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(1131443..1132336) Bifidobacterium animalis subsp. lactis DSM 10140 8010610 YP_002969978.1 CDS Balat_0990 NC_012815.1 1132444 1133448 D COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; ABC transporter substrate-binding protein 1132444..1133448 Bifidobacterium animalis subsp. lactis DSM 10140 8010611 YP_002969979.1 CDS Balat_0991 NC_012815.1 1133589 1134500 D COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn2+/Zn2+ ABC transporter ATPase 1133589..1134500 Bifidobacterium animalis subsp. lactis DSM 10140 8010612 YP_002969980.1 CDS Balat_0992 NC_012815.1 1134497 1135342 D COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease 1134497..1135342 Bifidobacterium animalis subsp. lactis DSM 10140 8010613 YP_002969981.1 CDS ispF NC_012815.1 1135453 1135956 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(1135453..1135956) Bifidobacterium animalis subsp. lactis DSM 10140 8010614 YP_002969982.1 CDS Balat_0994 NC_012815.1 1135953 1136549 R COG1329 Transcriptional regulators, similar to M.xanthus CarD; transcriptional regulator complement(1135953..1136549) Bifidobacterium animalis subsp. lactis DSM 10140 8010615 YP_002969983.1 CDS Balat_0995 NC_012815.1 1136726 1138939 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1136726..1138939 Bifidobacterium animalis subsp. lactis DSM 10140 8010616 YP_002969984.1 CDS Balat_0996 NC_012815.1 1138967 1139686 D COG0745 Response regulators consisting of aCheY-like receiver domain and a winged-helix DNA-binding domain; putative response regulator 1138967..1139686 Bifidobacterium animalis subsp. lactis DSM 10140 8010617 YP_002969985.1 CDS Balat_0997 NC_012815.1 1139692 1140792 D COG0642 Signal transduction histidine kinase; sensor protein 1139692..1140792 Bifidobacterium animalis subsp. lactis DSM 10140 8010618 YP_002969986.1 CDS Balat_0998 NC_012815.1 1140855 1141439 R COG1040 Predicted amidophosphoribosyltransferases; hypothetical protein complement(1140855..1141439) Bifidobacterium animalis subsp. lactis DSM 10140 8010619 YP_002969987.1 CDS Balat_0999 NC_012815.1 1141646 1142452 R COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein complement(1141646..1142452) Bifidobacterium animalis subsp. lactis DSM 10140 8010620 YP_002969988.1 CDS Balat_1000 NC_012815.1 1142653 1142973 D hypothetical protein 1142653..1142973 Bifidobacterium animalis subsp. lactis DSM 10140 8010621 YP_002969989.1 CDS Balat_1001 NC_012815.1 1142980 1144524 R hypothetical protein complement(1142980..1144524) Bifidobacterium animalis subsp. lactis DSM 10140 8010622 YP_002969990.1 CDS Balat_1002 NC_012815.1 1144521 1147616 R COG1216 Predicted glycosyltransferases; hypothetical protein complement(1144521..1147616) Bifidobacterium animalis subsp. lactis DSM 10140 8010623 YP_002969991.1 CDS Balat_1003 NC_012815.1 1147809 1149266 D COG1316 Transcriptional regulator; transcriptional regulator 1147809..1149266 Bifidobacterium animalis subsp. lactis DSM 10140 8010624 YP_002969992.1 CDS Balat_1004 NC_012815.1 1149811 1150746 D COG1316 Transcriptional regulator; transcriptional regulator 1149811..1150746 Bifidobacterium animalis subsp. lactis DSM 10140 8010625 YP_002969993.1 CDS Balat_1005 NC_012815.1 1150892 1152541 D COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA segregation ATPase 1150892..1152541 Bifidobacterium animalis subsp. lactis DSM 10140 8010626 YP_002969994.1 CDS Balat_1006 NC_012815.1 1152634 1152912 D hypothetical protein 1152634..1152912 Bifidobacterium animalis subsp. lactis DSM 10140 8010627 YP_002969995.1 CDS Balat_1007 NC_012815.1 1152997 1154475 R COG3920 Signal transduction histidine kinase; histidine kinase-like protein complement(1152997..1154475) Bifidobacterium animalis subsp. lactis DSM 10140 8010628 YP_002969996.1 CDS Balat_1008 NC_012815.1 1154609 1155493 D COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 1154609..1155493 Bifidobacterium animalis subsp. lactis DSM 10140 8010629 YP_002969997.1 CDS Balat_1009 NC_012815.1 1155574 1156056 R COG0782 Transcription elongation factor; transcription elongation factor GreA complement(1155574..1156056) Bifidobacterium animalis subsp. lactis DSM 10140 8010630 YP_002969998.1 CDS Balat_1010 NC_012815.1 1156142 1156549 R COG0545 FKBP-type peptidyl-prolyl cis-transisomerases 1; peptidyl-prolyl cis-trans isomerase complement(1156142..1156549) Bifidobacterium animalis subsp. lactis DSM 10140 8010631 YP_002969999.1 CDS Balat_1011 NC_012815.1 1156637 1158127 R COG1760 L-serine deaminase; L-serine dehydratase complement(1156637..1158127) Bifidobacterium animalis subsp. lactis DSM 10140 8010632 YP_002970000.1 CDS Balat_1012 NC_012815.1 1158168 1158692 R Cd efflux system component complement(1158168..1158692) Bifidobacterium animalis subsp. lactis DSM 10140 8010633 YP_002970001.1 CDS Balat_1014 NC_012815.1 1159093 1160115 R COG0248 Exopolyphosphatase; exopolyphosphatase complement(1159093..1160115) Bifidobacterium animalis subsp. lactis DSM 10140 8010635 YP_002970002.1 CDS Balat_1015 NC_012815.1 1160155 1160763 R COG1507 Uncharacterized conserved protein; hypothetical protein complement(1160155..1160763) Bifidobacterium animalis subsp. lactis DSM 10140 8010636 YP_002970003.1 CDS Balat_1016 NC_012815.1 1160835 1161407 R COG2919 Septum formation initiator; hypothetical protein complement(1160835..1161407) Bifidobacterium animalis subsp. lactis DSM 10140 8010637 YP_002970004.1 CDS eno NC_012815.1 1161505 1162797 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1161505..1162797) Bifidobacterium animalis subsp. lactis DSM 10140 8010638 YP_002970005.1 CDS Balat_1018 NC_012815.1 1163075 1163983 D COG0600 ABC-type nitrate/sulfonate/bicarbonatetransport system, permease component; binding-protein-dependent transport systems, inner membrane component 1163075..1163983 Bifidobacterium animalis subsp. lactis DSM 10140 8010639 YP_002970006.1 CDS Balat_1019 NC_012815.1 1164076 1165041 D COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; extracellular solute-binding protein 1164076..1165041 Bifidobacterium animalis subsp. lactis DSM 10140 8010640 YP_002970007.1 CDS Balat_1020 NC_012815.1 1165214 1165912 D COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporter 1165214..1165912 Bifidobacterium animalis subsp. lactis DSM 10140 8010641 YP_002970008.1 CDS Balat_1021 NC_012815.1 1166084 1169668 R COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor complement(1166084..1169668) Bifidobacterium animalis subsp. lactis DSM 10140 8010642 YP_002970009.1 CDS Balat_1022 NC_012815.1 1169658 1170257 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1169658..1170257) Bifidobacterium animalis subsp. lactis DSM 10140 8010643 YP_002970010.1 CDS Balat_1023 NC_012815.1 1170301 1170948 R COG1247 Sortase and related acyltransferases; N-acetyl transferase complement(1170301..1170948) Bifidobacterium animalis subsp. lactis DSM 10140 8010644 YP_002970011.1 CDS Balat_1024 NC_012815.1 1170964 1174131 R COG1615 Uncharacterized conserved protein; hypothetical protein complement(1170964..1174131) Bifidobacterium animalis subsp. lactis DSM 10140 8010645 YP_002970012.1 CDS Balat_1025 NC_012815.1 1174282 1175721 D COG1472 Beta-glucosidase-related glycosidases; B-hexosaminidase 1174282..1175721 Bifidobacterium animalis subsp. lactis DSM 10140 8010646 YP_002970013.1 CDS Balat_1026 NC_012815.1 1175781 1175975 R COG2879 Uncharacterized small protein; hypothetical protein complement(1175781..1175975) Bifidobacterium animalis subsp. lactis DSM 10140 8010647 YP_002970014.1 CDS Balat_1027 NC_012815.1 1176025 1178442 R COG1966 Carbon starvation protein, predicted membrane protein; carbon starvation protein A complement(1176025..1178442) Bifidobacterium animalis subsp. lactis DSM 10140 8010648 YP_002970015.1 CDS Balat_1028 NC_012815.1 1178473 1178652 R COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter complement(1178473..1178652) Bifidobacterium animalis subsp. lactis DSM 10140 8010649 YP_002970016.1 CDS Balat_1029 NC_012815.1 1178640 1179119 R COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein complement(1178640..1179119) Bifidobacterium animalis subsp. lactis DSM 10140 8010650 YP_002970017.1 CDS Balat_1030 NC_012815.1 1179353 1179898 R COG3910 Predicted ATPase; SMC domain-containing protein complement(1179353..1179898) Bifidobacterium animalis subsp. lactis DSM 10140 8010651 YP_002970018.1 CDS Balat_1031 NC_012815.1 1179941 1180132 R hypothetical protein complement(1179941..1180132) Bifidobacterium animalis subsp. lactis DSM 10140 8010652 YP_002970019.1 CDS Balat_1032 NC_012815.1 1180222 1180734 R COG1846 Transcriptional regulators; transcriptional regulator complement(1180222..1180734) Bifidobacterium animalis subsp. lactis DSM 10140 8010653 YP_002970020.1 CDS Balat_1033 NC_012815.1 1180777 1181241 R Nucleoside 2-deoxyribosyltransferase complement(1180777..1181241) Bifidobacterium animalis subsp. lactis DSM 10140 8010654 YP_002970021.1 CDS aspA NC_012815.1 1181418 1182887 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1181418..1182887 Bifidobacterium animalis subsp. lactis DSM 10140 8010655 YP_002970022.1 CDS Balat_1035 NC_012815.1 1183106 1183312 D COG1918 Fe2+ transport system protein A; hypothetical protein 1183106..1183312 Bifidobacterium animalis subsp. lactis DSM 10140 8010656 YP_002970023.1 CDS Balat_1036 NC_012815.1 1183361 1185412 D COG0370 Fe2+ transport system protein B; ferrous iron transport protein B 1183361..1185412 Bifidobacterium animalis subsp. lactis DSM 10140 8010657 YP_002970024.1 CDS Balat_1037 NC_012815.1 1185508 1185777 D hypothetical protein 1185508..1185777 Bifidobacterium animalis subsp. lactis DSM 10140 8010658 YP_002970025.1 CDS Balat_1038 NC_012815.1 1185916 1187475 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1185916..1187475 Bifidobacterium animalis subsp. lactis DSM 10140 8010659 YP_002970026.1 CDS Balat_1039 NC_012815.1 1187472 1188422 D COG3429 Glucose-6-P dehydrogenase subunit; hypothetical protein 1187472..1188422 Bifidobacterium animalis subsp. lactis DSM 10140 8010660 YP_002970027.1 CDS Balat_1040 NC_012815.1 1188502 1189293 D COG03636-phosphogluconolactonase/Glucosamine-6- phosphateisomerase/deaminase; 6-phosphogluconolactonase 1188502..1189293 Bifidobacterium animalis subsp. lactis DSM 10140 8010661 YP_002970028.1 CDS Balat_1041 NC_012815.1 1189372 1190829 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(1189372..1190829) Bifidobacterium animalis subsp. lactis DSM 10140 8010662 YP_002970029.1 CDS Balat_1042 NC_012815.1 1190888 1191595 R COG3340 Peptidase E; hypothetical protein complement(1190888..1191595) Bifidobacterium animalis subsp. lactis DSM 10140 8010663 YP_002970030.1 CDS Balat_1043 NC_012815.1 1191746 1193110 D COG1114 Branched-chain amino acid permeases; Branched-chain amino acid permease 1191746..1193110 Bifidobacterium animalis subsp. lactis DSM 10140 8010664 YP_002970031.1 CDS Balat_1044 NC_012815.1 1193127 1194119 R COG0225 Peptide methionine sulfoxide reductase; Peptide methionine sulfoxide reductase-like protein complement(1193127..1194119) Bifidobacterium animalis subsp. lactis DSM 10140 8010665 YP_002970032.1 CDS Balat_1045 NC_012815.1 1194127 1196847 R COG4633 Uncharacterized protein conserved in bacteria; ActP copper transport ATPase complement(1194127..1196847) Bifidobacterium animalis subsp. lactis DSM 10140 8010666 YP_002970033.1 CDS Balat_1046 NC_012815.1 1196903 1197943 D COG0300 Short-chain dehydrogenases of various substrate specificities; short-chain dehydrogenase/reductase SDR 1196903..1197943 Bifidobacterium animalis subsp. lactis DSM 10140 8010667 YP_002970034.1 CDS Balat_1047 NC_012815.1 1198196 1200133 R COG0513 Superfamily II DNA and RNA helicases; ATP-dependent RNA helicase complement(1198196..1200133) Bifidobacterium animalis subsp. lactis DSM 10140 8010668 YP_002970035.1 CDS Balat_1048 NC_012815.1 1200357 1201475 D COG2855 Predicted membrane protein; hypothetical protein 1200357..1201475 Bifidobacterium animalis subsp. lactis DSM 10140 8010669 YP_002970036.1 CDS Balat_1049 NC_012815.1 1201704 1203035 D COG2233 Xanthine/uracil permeases; purine or uracil permease 1201704..1203035 Bifidobacterium animalis subsp. lactis DSM 10140 8010670 YP_002970037.1 CDS Balat_1050 NC_012815.1 1203174 1204247 D COG0657 Esterase/lipase; lipase 1203174..1204247 Bifidobacterium animalis subsp. lactis DSM 10140 8010671 YP_002970038.1 CDS Balat_1051 NC_012815.1 1204332 1204712 D hypothetical protein 1204332..1204712 Bifidobacterium animalis subsp. lactis DSM 10140 8010672 YP_002970039.1 CDS Balat_1052 NC_012815.1 1204878 1205228 D COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 1204878..1205228 Bifidobacterium animalis subsp. lactis DSM 10140 8010673 YP_002970040.1 CDS Balat_1053 NC_012815.1 1205317 1206411 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1205317..1206411) Bifidobacterium animalis subsp. lactis DSM 10140 8010674 YP_002970041.1 CDS Balat_1054 NC_012815.1 1206544 1207338 R COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase complement(1206544..1207338) Bifidobacterium animalis subsp. lactis DSM 10140 8010675 YP_002970042.1 CDS Balat_1055 NC_012815.1 1207401 1208738 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); proline iminopeptidase complement(1207401..1208738) Bifidobacterium animalis subsp. lactis DSM 10140 8010676 YP_002970043.1 CDS Balat_1056 NC_012815.1 1208861 1211416 D COG4585 Signal transduction histidine kinase; histidine kinase sensor of two-component system 1208861..1211416 Bifidobacterium animalis subsp. lactis DSM 10140 8010677 YP_002970044.1 CDS Balat_1057 NC_012815.1 1211536 1212216 D COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; putative response regulator 1211536..1212216 Bifidobacterium animalis subsp. lactis DSM 10140 8010678 YP_002970045.1 CDS Balat_1058 NC_012815.1 1212332 1214938 R COG0577 ABC-type antimicrobial peptide transport system, permease component; SalY-type ABC antimicrobial peptide transport system permease complement(1212332..1214938) Bifidobacterium animalis subsp. lactis DSM 10140 8010679 YP_002970046.1 CDS Balat_1059 NC_012815.1 1214982 1215920 R COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein complement(1214982..1215920) Bifidobacterium animalis subsp. lactis DSM 10140 8010680 YP_002970047.1 CDS Balat_1060 NC_012815.1 1216082 1216885 R COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt transport protein complement(1216082..1216885) Bifidobacterium animalis subsp. lactis DSM 10140 8010681 YP_002970048.1 CDS Balat_1061 NC_012815.1 1216885 1218420 R COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase complement(1216885..1218420) Bifidobacterium animalis subsp. lactis DSM 10140 8010682 YP_002970049.1 CDS Balat_1062 NC_012815.1 1218501 1218662 R hypothetical protein complement(1218501..1218662) Bifidobacterium animalis subsp. lactis DSM 10140 8010683 YP_002970050.1 CDS Balat_1063 NC_012815.1 1218669 1219991 R COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase complement(1218669..1219991) Bifidobacterium animalis subsp. lactis DSM 10140 8010684 YP_002970051.1 CDS Balat_1064 NC_012815.1 1220297 1221166 D COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxine kinase 1220297..1221166 Bifidobacterium animalis subsp. lactis DSM 10140 8010685 YP_002970052.1 CDS Balat_1065 NC_012815.1 1221363 1221839 D COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein 1221363..1221839 Bifidobacterium animalis subsp. lactis DSM 10140 8010686 YP_002970053.1 CDS Balat_1066 NC_012815.1 1221839 1223371 D COG0606 Predicted ATPase with chaperone activity; putative ATP-dependent serine protease 1221839..1223371 Bifidobacterium animalis subsp. lactis DSM 10140 8010687 YP_002970054.1 CDS Balat_1067 NC_012815.1 1223405 1224550 D COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 1223405..1224550 Bifidobacterium animalis subsp. lactis DSM 10140 8010688 YP_002970055.1 CDS Balat_1068 NC_012815.1 1224603 1226438 D COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit 1224603..1226438 Bifidobacterium animalis subsp. lactis DSM 10140 8010689 YP_002970056.1 CDS Balat_1069 NC_012815.1 1226547 1227503 D COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Succinate dehydrogenase/fumarate reductase Fe-Sprotein subunit 1226547..1227503 Bifidobacterium animalis subsp. lactis DSM 10140 8010690 YP_002970057.1 CDS Balat_1070 NC_012815.1 1227516 1228187 D COG4122 Predicted O-methyltransferase; methyltransferase 1227516..1228187 Bifidobacterium animalis subsp. lactis DSM 10140 8010691 YP_002970058.1 CDS Balat_1071 NC_012815.1 1228250 1229053 R COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein complement(1228250..1229053) Bifidobacterium animalis subsp. lactis DSM 10140 8010692 YP_002970059.1 CDS Balat_1072 NC_012815.1 1229132 1230532 R COG3004 Na+/H+ antiporter; Kef-type K+ transport systems membrane component complement(1229132..1230532) Bifidobacterium animalis subsp. lactis DSM 10140 8010693 YP_002970060.1 CDS Balat_1073 NC_012815.1 1230618 1231838 R COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; class I and II aminotransferase complement(1230618..1231838) Bifidobacterium animalis subsp. lactis DSM 10140 8010694 YP_002970061.1 CDS clpX NC_012815.1 1232288 1233616 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1232288..1233616) Bifidobacterium animalis subsp. lactis DSM 10140 8010697 YP_002970062.1 CDS clpP NC_012815.1 1233718 1234419 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1233718..1234419) Bifidobacterium animalis subsp. lactis DSM 10140 8010698 YP_002970063.1 CDS Balat_1078 NC_012815.1 1234422 1235036 R COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit 2 complement(1234422..1235036) Bifidobacterium animalis subsp. lactis DSM 10140 8010699 YP_002970064.1 CDS Balat_1079 NC_012815.1 1235135 1236532 R COG0038 Chloride channel protein EriC; hypothetical protein complement(1235135..1236532) Bifidobacterium animalis subsp. lactis DSM 10140 8010700 YP_002970065.1 CDS tig NC_012815.1 1236607 1237992 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(1236607..1237992) Bifidobacterium animalis subsp. lactis DSM 10140 8010701 YP_002970066.1 CDS Balat_1081 NC_012815.1 1238050 1239351 R COG0349 Ribonuclease D; hypothetical protein complement(1238050..1239351) Bifidobacterium animalis subsp. lactis DSM 10140 8010702 YP_002970067.1 CDS Balat_1082 NC_012815.1 1239452 1240354 R COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate formate-lyase 1 activating enzyme complement(1239452..1240354) Bifidobacterium animalis subsp. lactis DSM 10140 8010703 YP_002970068.1 CDS Balat_1083 NC_012815.1 1240445 1242823 R COG1882 Pyruvate-formate lyase; formate acetyltransferase complement(1240445..1242823) Bifidobacterium animalis subsp. lactis DSM 10140 8010704 YP_002970069.1 CDS Balat_1084 NC_012815.1 1243049 1243249 R hypothetical protein complement(1243049..1243249) Bifidobacterium animalis subsp. lactis DSM 10140 8010705 YP_002970070.1 CDS Balat_1085 NC_012815.1 1243291 1244991 R COG0388 Predicted amidohydrolase; putative amidohydrolase complement(1243291..1244991) Bifidobacterium animalis subsp. lactis DSM 10140 8010706 YP_002970071.1 CDS Balat_1086 NC_012815.1 1245211 1246374 R COG1473 Metal-dependentamidase/aminoacylase/carboxypeptidase; hypothetical protein complement(1245211..1246374) Bifidobacterium animalis subsp. lactis DSM 10140 8010707 YP_002970072.1 CDS Balat_1087 NC_012815.1 1246479 1247189 R COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter permease complement(1246479..1247189) Bifidobacterium animalis subsp. lactis DSM 10140 8010708 YP_002970073.1 CDS Balat_1088 NC_012815.1 1247693 1248484 R COG1135 ABC-type metal ion transport system, ATPase component; ABC transporter ATP-binding protein complement(1247693..1248484) Bifidobacterium animalis subsp. lactis DSM 10140 8010709 YP_002970074.1 CDS Balat_1089 NC_012815.1 1248671 1249669 R COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; metal ion ABC transporter periplasmic protein complement(1248671..1249669) Bifidobacterium animalis subsp. lactis DSM 10140 8010710 YP_002970075.1 CDS Balat_1090 NC_012815.1 1249899 1250423 D COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase - cyclophilin family); peptidyl-prolyl cis-trans isomerase 1249899..1250423 Bifidobacterium animalis subsp. lactis DSM 10140 8010711 YP_002970076.1 CDS Balat_1091 NC_012815.1 1250518 1252851 R COG0317 Guanosine polyphosphatepyrophosphohydrolases/synthetases; GTP pyrophosphokinase complement(1250518..1252851) Bifidobacterium animalis subsp. lactis DSM 10140 8010712 YP_002970077.1 CDS Balat_1092 NC_012815.1 1252958 1253425 R COG0756 dUTPase; dUTPase complement(1252958..1253425) Bifidobacterium animalis subsp. lactis DSM 10140 8010713 YP_002970078.1 CDS Balat_1093 NC_012815.1 1253425 1253718 R hypothetical protein complement(1253425..1253718) Bifidobacterium animalis subsp. lactis DSM 10140 8010714 YP_002970079.1 CDS Balat_1094 NC_012815.1 1253845 1255179 D hypothetical protein 1253845..1255179 Bifidobacterium animalis subsp. lactis DSM 10140 8010715 YP_002970080.1 CDS Balat_1095 NC_012815.1 1255191 1256468 R COG1524 Uncharacterized proteins of the AP superfamily; hypothetical protein complement(1255191..1256468) Bifidobacterium animalis subsp. lactis DSM 10140 8010716 YP_002970081.1 CDS Balat_1096 NC_012815.1 1256591 1259266 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1256591..1259266 Bifidobacterium animalis subsp. lactis DSM 10140 8010717 YP_002970082.1 CDS glcU NC_012815.1 1259349 1260308 R COG4975 Putative glucose uptake permease; putative glucose uptake permease complement(1259349..1260308) Bifidobacterium animalis subsp. lactis DSM 10140 8010718 YP_002970083.1 CDS Balat_1098 NC_012815.1 1260440 1265101 R COG1201 Lhr-like helicases; ATP-dependent helicase II complement(1260440..1265101) Bifidobacterium animalis subsp. lactis DSM 10140 8010719 YP_002970084.1 CDS Balat_1099 NC_012815.1 1265129 1265758 R major facilitator transporter complement(1265129..1265758) Bifidobacterium animalis subsp. lactis DSM 10140 8010720 YP_002970085.1 CDS Balat_1100 NC_012815.1 1266477 1267658 R COG0738 Fucose permease; hypothetical protein complement(1266477..1267658) Bifidobacterium animalis subsp. lactis DSM 10140 8010721 YP_002970086.1 CDS Balat_1101 NC_012815.1 1267771 1268943 D COG0438 Glycosyltransferase; phosphatidylinositol alpha-mannosyltransferase 1267771..1268943 Bifidobacterium animalis subsp. lactis DSM 10140 8010722 YP_002970087.1 CDS Balat_1102 NC_012815.1 1269078 1271417 R COG0187 Type IIA topoisomerase (DNA gyrase/topo II,topoisomerase IV, B subunit); DNA gyrase subunit B complement(1269078..1271417) Bifidobacterium animalis subsp. lactis DSM 10140 8010723 YP_002970088.1 CDS Balat_1103 NC_012815.1 1271552 1273018 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor complement(1271552..1273018) Bifidobacterium animalis subsp. lactis DSM 10140 8010724 YP_002970089.1 CDS Balat_1104 NC_012815.1 1273150 1273854 R hypothetical protein complement(1273150..1273854) Bifidobacterium animalis subsp. lactis DSM 10140 8010725 YP_002970090.1 CDS Balat_1105 NC_012815.1 1274035 1275135 D COG0142 Geranylgeranyl pyrophosphate synthase; bifunctional short chain isoprenyl diphosphate synthase 1274035..1275135 Bifidobacterium animalis subsp. lactis DSM 10140 8010726 YP_002970091.1 CDS Balat_1106 NC_012815.1 1275195 1277420 D COG0515 Serine/threonine protein kinase; serine-threonine protein kinase 1275195..1277420 Bifidobacterium animalis subsp. lactis DSM 10140 8010727 YP_002970092.1 CDS Balat_1107 NC_012815.1 1277470 1278210 R COG0204 1-acyl-sn-glycerol-3-phosphateacyltransferase; hypothetical protein complement(1277470..1278210) Bifidobacterium animalis subsp. lactis DSM 10140 8010728 YP_002970093.1 CDS Balat_1108 NC_012815.1 1278260 1278826 D hypothetical protein 1278260..1278826 Bifidobacterium animalis subsp. lactis DSM 10140 8010729 YP_002970094.1 CDS trpD NC_012815.1 1278918 1279970 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1278918..1279970) Bifidobacterium animalis subsp. lactis DSM 10140 8010730 YP_002970095.1 CDS Balat_1110 NC_012815.1 1280104 1283028 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1280104..1283028) Bifidobacterium animalis subsp. lactis DSM 10140 8010731 YP_002970096.1 CDS Balat_1111 NC_012815.1 1283236 1283922 R COG1544 Ribosome-associated protein Y (PSrp-1); hypothetical protein complement(1283236..1283922) Bifidobacterium animalis subsp. lactis DSM 10140 8010732 YP_002970097.1 CDS Balat_1112 NC_012815.1 1284395 1284526 D hypothetical protein 1284395..1284526 Bifidobacterium animalis subsp. lactis DSM 10140 8010733 YP_002970098.1 CDS Balat_1113 NC_012815.1 1284594 1285223 R COG2137 Uncharacterized protein conserved in bacteria; RecX-like protein complement(1284594..1285223) Bifidobacterium animalis subsp. lactis DSM 10140 8010734 YP_002970099.1 CDS recA NC_012815.1 1285333 1286481 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1285333..1286481) Bifidobacterium animalis subsp. lactis DSM 10140 8010735 YP_002970100.1 CDS Balat_1115 NC_012815.1 1286753 1287004 R hypothetical protein complement(1286753..1287004) Bifidobacterium animalis subsp. lactis DSM 10140 8010736 YP_002970102.1 CDS Balat_1117 NC_012815.1 1287670 1288296 R COG1546 Uncharacterized protein (competence- andmitomycin-induced); CinA-like protein complement(1287670..1288296) Bifidobacterium animalis subsp. lactis DSM 10140 8010738 YP_002970103.1 CDS Balat_1118 NC_012815.1 1288479 1289102 R COG0558 Phosphatidylglycerophosphate synthase; DP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1288479..1289102) Bifidobacterium animalis subsp. lactis DSM 10140 8010739 YP_002970104.1 CDS Balat_1119 NC_012815.1 1289248 1291863 R COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase ftsK complement(1289248..1291863) Bifidobacterium animalis subsp. lactis DSM 10140 8010740 YP_002970105.1 CDS miaA NC_012815.1 1292121 1293155 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1292121..1293155) Bifidobacterium animalis subsp. lactis DSM 10140 8010741 YP_002970106.1 CDS Balat_1121 NC_012815.1 1293136 1294611 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(1293136..1294611) Bifidobacterium animalis subsp. lactis DSM 10140 8010742 YP_002970107.1 CDS Balat_1122 NC_012815.1 1294687 1295505 D COG2357 Uncharacterized protein conserved in bacteria; hypothetical protein 1294687..1295505 Bifidobacterium animalis subsp. lactis DSM 10140 8010743 YP_002970108.1 CDS Balat_1123 NC_012815.1 1295591 1296376 R COG0670 Integral membrane protein, interacts withFtsH; hypothetical protein complement(1295591..1296376) Bifidobacterium animalis subsp. lactis DSM 10140 8010744 YP_002970109.1 CDS Balat_1124 NC_012815.1 1296638 1297663 D COG3804 Uncharacterized conserved protein related to dihydrodipicolinate reductase; hypothetical protein 1296638..1297663 Bifidobacterium animalis subsp. lactis DSM 10140 8010745 YP_002970110.1 CDS Balat_1125 NC_012815.1 1299079 1300359 R multidrug ABC transporter permease complement(1299079..1300359) Bifidobacterium animalis subsp. lactis DSM 10140 8010746 YP_002970111.1 CDS Balat_1126 NC_012815.1 1300393 1301382 R COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein complement(1300393..1301382) Bifidobacterium animalis subsp. lactis DSM 10140 8010747 YP_002970112.1 CDS Balat_1127 NC_012815.1 1301529 1302695 D COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 1301529..1302695 Bifidobacterium animalis subsp. lactis DSM 10140 8010748 YP_002970113.1 CDS Balat_1128 NC_012815.1 1302692 1303348 D COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 1302692..1303348 Bifidobacterium animalis subsp. lactis DSM 10140 8010749 YP_002970114.1 CDS Balat_1129 NC_012815.1 1303330 1304145 R hypothetical protein complement(1303330..1304145) Bifidobacterium animalis subsp. lactis DSM 10140 8010750 YP_002970115.1 CDS Balat_1130 NC_012815.1 1304174 1305307 R COG3464 Transposase and inactivated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein complement(1304174..1305307) Bifidobacterium animalis subsp. lactis DSM 10140 8010751 YP_002970116.1 CDS Balat_1131 NC_012815.1 1305514 1306827 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(1305514..1306827) Bifidobacterium animalis subsp. lactis DSM 10140 8010752 YP_002970117.1 CDS Balat_1132 NC_012815.1 1306975 1307616 R COG0110 Acetyltransferase (isoleucine patch superfamily); galactoside O-acetyltransferase complement(1306975..1307616) Bifidobacterium animalis subsp. lactis DSM 10140 8010753 YP_002970118.1 CDS Balat_1133 NC_012815.1 1307789 1308040 D hypothetical protein 1307789..1308040 Bifidobacterium animalis subsp. lactis DSM 10140 8010754 YP_002970119.1 CDS Balat_1134 NC_012815.1 1308124 1310823 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1308124..1310823) Bifidobacterium animalis subsp. lactis DSM 10140 8010755 YP_002970120.1 CDS Balat_1135 NC_012815.1 1310891 1313461 R COG0474 Cation transport ATPase; cation-transporting ATPase complement(1310891..1313461) Bifidobacterium animalis subsp. lactis DSM 10140 8010756 YP_002970121.1 CDS Balat_1136 NC_012815.1 1313510 1314097 R hypothetical protein complement(1313510..1314097) Bifidobacterium animalis subsp. lactis DSM 10140 8010757 YP_002970122.1 CDS Balat_1137 NC_012815.1 1314433 1315743 R COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5--methyltransferase); RNA methyltransferase complement(1314433..1315743) Bifidobacterium animalis subsp. lactis DSM 10140 8010758 YP_002970123.1 CDS Balat_1138 NC_012815.1 1315857 1316627 R hypothetical protein complement(1315857..1316627) Bifidobacterium animalis subsp. lactis DSM 10140 8010759 YP_002970124.1 CDS Balat_1139 NC_012815.1 1316696 1317553 R hypothetical protein complement(1316696..1317553) Bifidobacterium animalis subsp. lactis DSM 10140 8010760 YP_002970125.1 CDS Balat_1140 NC_012815.1 1317687 1318547 R COG0708 Exonuclease III; exodeoxyribonuclease complement(1317687..1318547) Bifidobacterium animalis subsp. lactis DSM 10140 8010761 YP_002970126.1 CDS Balat_1141 NC_012815.1 1318721 1319395 D hypothetical protein 1318721..1319395 Bifidobacterium animalis subsp. lactis DSM 10140 8010762 YP_002970127.1 CDS Balat_1142 NC_012815.1 1319655 1321718 R COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; dipeptide transport ATP-binding protein complement(1319655..1321718) Bifidobacterium animalis subsp. lactis DSM 10140 8010763 YP_002970128.1 CDS Balat_1143 NC_012815.1 1321715 1322671 R COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease complement(1321715..1322671) Bifidobacterium animalis subsp. lactis DSM 10140 8010764 YP_002970129.1 CDS Balat_1144 NC_012815.1 1322685 1323611 R COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease complement(1322685..1323611) Bifidobacterium animalis subsp. lactis DSM 10140 8010765 YP_002970130.1 CDS Balat_1145 NC_012815.1 1323911 1325551 R COG0747 ABC-type dipeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic protein complement(1323911..1325551) Bifidobacterium animalis subsp. lactis DSM 10140 8010766 YP_002970131.1 CDS xerC NC_012815.1 1325828 1326763 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(1325828..1326763) Bifidobacterium animalis subsp. lactis DSM 10140 8010767 YP_002970132.1 CDS Balat_1147 NC_012815.1 1327002 1327808 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 1327002..1327808 Bifidobacterium animalis subsp. lactis DSM 10140 8010768 YP_002970133.1 CDS Balat_1148 NC_012815.1 1327816 1330650 D COG0577 ABC-type antimicrobial peptide transport system, permease component; putative ABC transporter integral membrane protein 1327816..1330650 Bifidobacterium animalis subsp. lactis DSM 10140 8010769 YP_002970134.1 CDS Balat_1149 NC_012815.1 1330795 1331046 D hypothetical protein 1330795..1331046 Bifidobacterium animalis subsp. lactis DSM 10140 8010770 YP_002970135.1 CDS Balat_1150 NC_012815.1 1331062 1332156 R COG0287 Prephenate dehydrogenase; prephenate dehydrogenase complement(1331062..1332156) Bifidobacterium animalis subsp. lactis DSM 10140 8010771 YP_002970136.1 CDS Balat_1151 NC_012815.1 1332165 1333280 R COG0077 Prephenate dehydratase; chorismate mutase complement(1332165..1333280) Bifidobacterium animalis subsp. lactis DSM 10140 8010772 YP_002970137.1 CDS Balat_1152 NC_012815.1 1333303 1333812 R hypothetical protein complement(1333303..1333812) Bifidobacterium animalis subsp. lactis DSM 10140 8010773 YP_002970138.1 CDS Balat_1153 NC_012815.1 1333922 1335853 R COG1217 Predicted membrane GTPase involved instress response; GTP-binding elongation factor TypA/BipA complement(1333922..1335853) Bifidobacterium animalis subsp. lactis DSM 10140 8010774 YP_002970139.1 CDS Balat_1154 NC_012815.1 1336207 1337616 R COG0477 Permeases of the major facilitator superfamily; sugar transporter complement(1336207..1337616) Bifidobacterium animalis subsp. lactis DSM 10140 8010775 YP_002970140.1 CDS Balat_1155 NC_012815.1 1337678 1338487 R COG1051 ADP-ribose pyrophosphatase; hypothetical protein complement(1337678..1338487) Bifidobacterium animalis subsp. lactis DSM 10140 8010776 YP_002970141.1 CDS Balat_1156 NC_012815.1 1338688 1339536 R COG1192 ATPases involved in chromosome partitioning; hypothetical protein complement(1338688..1339536) Bifidobacterium animalis subsp. lactis DSM 10140 8010777 YP_002970142.1 CDS Balat_1157 NC_012815.1 1339640 1340563 R COG4974 Site-specific recombinase XerD; Integrase complement(1339640..1340563) Bifidobacterium animalis subsp. lactis DSM 10140 8010778 YP_002970143.1 CDS rplT NC_012815.1 1340955 1341338 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1340955..1341338) Bifidobacterium animalis subsp. lactis DSM 10140 8010779 YP_002970144.1 CDS rpmI NC_012815.1 1341388 1341579 R 50S ribosomal protein L35 complement(1341388..1341579) Bifidobacterium animalis subsp. lactis DSM 10140 8010780 YP_002970145.1 CDS Balat_1160 NC_012815.1 1341623 1342297 R COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 complement(1341623..1342297) Bifidobacterium animalis subsp. lactis DSM 10140 8010781 YP_002970146.1 CDS Balat_1161 NC_012815.1 1342749 1343555 D COG1564 Thiamine pyrophosphokinase; hypothetical protein 1342749..1343555 Bifidobacterium animalis subsp. lactis DSM 10140 8010782 YP_002970147.1 CDS Balat_1162 NC_012815.1 1343786 1344844 D COG0057 Glyceraldehyde-3-phosphatedehydrogenase/erythrose-4- phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 1343786..1344844 Bifidobacterium animalis subsp. lactis DSM 10140 8010783 YP_002970148.1 CDS Balat_1163 NC_012815.1 1345267 1345776 D COG2606 Uncharacterized conserved protein; hypothetical protein 1345267..1345776 Bifidobacterium animalis subsp. lactis DSM 10140 8010784 YP_002970149.1 CDS ispH NC_012815.1 1346004 1346981 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(1346004..1346981) Bifidobacterium animalis subsp. lactis DSM 10140 8010785 YP_002970150.1 CDS Balat_1165 NC_012815.1 1347071 1348063 D COG2017 Galactose mutarotase and related enzymes; hypothetical protein 1347071..1348063 Bifidobacterium animalis subsp. lactis DSM 10140 8010786 YP_002970151.1 CDS Balat_1166 NC_012815.1 1348412 1348723 R hypothetical protein complement(1348412..1348723) Bifidobacterium animalis subsp. lactis DSM 10140 8010787 YP_002970152.1 CDS Balat_1167 NC_012815.1 1348720 1349463 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(1348720..1349463) Bifidobacterium animalis subsp. lactis DSM 10140 8010788 YP_002970153.1 CDS murE NC_012815.1 1349602 1351152 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1349602..1351152 Bifidobacterium animalis subsp. lactis DSM 10140 8010789 YP_002970154.1 CDS Balat_1169 NC_012815.1 1351203 1352252 D COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 1351203..1352252 Bifidobacterium animalis subsp. lactis DSM 10140 8010790 YP_002970155.1 CDS Balat_1170 NC_012815.1 1352488 1354053 R COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase complement(1352488..1354053) Bifidobacterium animalis subsp. lactis DSM 10140 8010791 YP_002970156.1 CDS Balat_1171 NC_012815.1 1354191 1354814 D COG2197 Response regulator containing a CheY-likereceiver domain and an HTH DNA-binding domain; response regulator 1354191..1354814 Bifidobacterium animalis subsp. lactis DSM 10140 8010792 YP_002970157.1 CDS Balat_1172 NC_012815.1 1354816 1355970 D COG4585 Signal transduction histidine kinase; hypothetical protein 1354816..1355970 Bifidobacterium animalis subsp. lactis DSM 10140 8010793 YP_002970158.1 CDS Balat_1173 NC_012815.1 1355983 1356774 R hypothetical protein complement(1355983..1356774) Bifidobacterium animalis subsp. lactis DSM 10140 8010794 YP_002970159.1 CDS Balat_1174 NC_012815.1 1357003 1358574 D COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 1357003..1358574 Bifidobacterium animalis subsp. lactis DSM 10140 8010795 YP_002970160.1 CDS Balat_1175 NC_012815.1 1358598 1359125 D COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein 1358598..1359125 Bifidobacterium animalis subsp. lactis DSM 10140 8010796 YP_002970161.1 CDS Balat_1176 NC_012815.1 1359378 1360583 D COG1940 Transcriptional regulator/sugar kinase; ROK family transcriptional regulator 1359378..1360583 Bifidobacterium animalis subsp. lactis DSM 10140 8010797 YP_002970162.1 CDS Balat_1177 NC_012815.1 1360646 1361542 D COG0524 Sugar kinases, ribokinase family; 2-dehydro-3-deoxygluconokinase 1360646..1361542 Bifidobacterium animalis subsp. lactis DSM 10140 8010798 YP_002970163.1 CDS Balat_1178 NC_012815.1 1361641 1362108 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1361641..1362108 Bifidobacterium animalis subsp. lactis DSM 10140 8010799 YP_002970164.1 CDS Balat_1179 NC_012815.1 1362381 1363481 R COG0582 Integrase; phage-related integrase complement(1362381..1363481) Bifidobacterium animalis subsp. lactis DSM 10140 8010800 YP_002970165.1 CDS Balat_1180 NC_012815.1 1363694 1364311 R hypothetical protein complement(1363694..1364311) Bifidobacterium animalis subsp. lactis DSM 10140 8010801 YP_002970166.1 CDS Balat_1181 NC_012815.1 1364463 1364669 D COG3311 Predicted transcriptional regulator; hypothetical protein 1364463..1364669 Bifidobacterium animalis subsp. lactis DSM 10140 8010802 YP_002970167.1 CDS Balat_1182 NC_012815.1 1364684 1364896 D hypothetical protein 1364684..1364896 Bifidobacterium animalis subsp. lactis DSM 10140 8010803 YP_002970168.1 CDS Balat_1183 NC_012815.1 1364909 1365145 D hypothetical protein 1364909..1365145 Bifidobacterium animalis subsp. lactis DSM 10140 8010804 YP_002970169.1 CDS Balat_1184 NC_012815.1 1365150 1365341 D hypothetical protein 1365150..1365341 Bifidobacterium animalis subsp. lactis DSM 10140 8010805 YP_002970170.1 CDS Balat_1185 NC_012815.1 1365329 1365520 D hypothetical protein 1365329..1365520 Bifidobacterium animalis subsp. lactis DSM 10140 8010806 YP_002970171.1 CDS Balat_1186 NC_012815.1 1365511 1366713 D COG0305 Replicative DNA helicase; hypothetical protein 1365511..1366713 Bifidobacterium animalis subsp. lactis DSM 10140 8010807 YP_002970172.1 CDS Balat_1187 NC_012815.1 1366951 1367223 D hypothetical protein 1366951..1367223 Bifidobacterium animalis subsp. lactis DSM 10140 8010808 YP_002970173.1 CDS Balat_1188 NC_012815.1 1367220 1367408 D hypothetical protein 1367220..1367408 Bifidobacterium animalis subsp. lactis DSM 10140 8010809 YP_002970174.1 CDS Balat_1189 NC_012815.1 1367431 1367667 D hypothetical protein 1367431..1367667 Bifidobacterium animalis subsp. lactis DSM 10140 8010810 YP_002970175.1 CDS Balat_1190 NC_012815.1 1367664 1367981 D hypothetical protein 1367664..1367981 Bifidobacterium animalis subsp. lactis DSM 10140 8010811 YP_002970176.1 CDS Balat_1191 NC_012815.1 1368397 1370160 D COG3740 Phage head maturation protease; HK97 family phage prohead protease 1368397..1370160 Bifidobacterium animalis subsp. lactis DSM 10140 8010812 YP_002970177.1 CDS Balat_1192 NC_012815.1 1370172 1370393 D hypothetical protein 1370172..1370393 Bifidobacterium animalis subsp. lactis DSM 10140 8010813 YP_002970178.1 CDS Balat_1193 NC_012815.1 1371135 1372865 R COG1123 ATPase components of various ABC-typetransport systems, contain duplicated ATPase; peptide ABC transporter ATPase complement(1371135..1372865) Bifidobacterium animalis subsp. lactis DSM 10140 8010814 YP_002970179.1 CDS Balat_1194 NC_012815.1 1372855 1374042 R COG1173 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; peptide ABC transporter permease complement(1372855..1374042) Bifidobacterium animalis subsp. lactis DSM 10140 8010815 YP_002970180.1 CDS Balat_1195 NC_012815.1 1374074 1375165 R COG0601 ABC-type dipeptide/oligopeptide/nickeltransport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease complement(1374074..1375165) Bifidobacterium animalis subsp. lactis DSM 10140 8010816 YP_002970181.1 CDS Balat_1196 NC_012815.1 1377127 1378380 R COG1589 Cell division septal protein; cell division protein complement(1377127..1378380) Bifidobacterium animalis subsp. lactis DSM 10140 8010817 YP_002970182.1 CDS Balat_1197 NC_012815.1 1378541 1380082 R COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate--L-alanine ligase complement(1378541..1380082) Bifidobacterium animalis subsp. lactis DSM 10140 8010818 YP_002970183.1 CDS murG NC_012815.1 1380123 1381307 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase complement(1380123..1381307) Bifidobacterium animalis subsp. lactis DSM 10140 8010819 YP_002970184.1 CDS Balat_1199 NC_012815.1 1381362 1382744 R COG0772 Bacterial cell division membrane protein; FtsW-like protein complement(1381362..1382744) Bifidobacterium animalis subsp. lactis DSM 10140 8010820 YP_002970185.1 CDS Balat_1200 NC_012815.1 1382725 1384170 R COG0771 UDP-N-acetylmuramoylalanine-D-glutamateligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase complement(1382725..1384170) Bifidobacterium animalis subsp. lactis DSM 10140 8010821 YP_002970186.1 CDS mraY NC_012815.1 1384272 1385378 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1384272..1385378) Bifidobacterium animalis subsp. lactis DSM 10140 8010822 YP_002970187.1 CDS Balat_1202 NC_012815.1 1385430 1386920 R COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(1385430..1386920) Bifidobacterium animalis subsp. lactis DSM 10140 8010823 YP_002970188.1 CDS Balat_1203 NC_012815.1 1386958 1387839 R COG0769 UDP-N-acetylmuramyl tripeptide synthase; hypothetical protein complement(1386958..1387839) Bifidobacterium animalis subsp. lactis DSM 10140 8010824 YP_002970189.1 CDS Balat_1204 NC_012815.1 1387854 1389650 R COG0768 Cell division proteinFtsI/ penicillin-binding protein 2; peptidoglycan synthetase; penicillin-binding protein 3 complement(1387854..1389650) Bifidobacterium animalis subsp. lactis DSM 10140 8010825 YP_002970190.1 CDS Balat_1205 NC_012815.1 1389647 1390177 R hypothetical protein complement(1389647..1390177) Bifidobacterium animalis subsp. lactis DSM 10140 8010826 YP_002970191.1 CDS mraW NC_012815.1 1390179 1391240 R COG0275 Predicted S-adenosylmethionine-dependentmethyltransferase involved in cell envelope biogenesis; S-adenosyl-methyltransferase MraW complement(1390179..1391240) Bifidobacterium animalis subsp. lactis DSM 10140 8010827 YP_002970192.1 CDS Balat_1207 NC_012815.1 1391240 1391725 R COG2001 Uncharacterized protein conserved in bacteria; protein mraZ complement(1391240..1391725) Bifidobacterium animalis subsp. lactis DSM 10140 8010828 YP_002970193.1 CDS Balat_1208 NC_012815.1 1392079 1394340 D COG3973 Superfamily I DNA and RNA helicases; hypothetical protein 1392079..1394340 Bifidobacterium animalis subsp. lactis DSM 10140 8010829 YP_002970194.1 CDS Balat_1209 NC_012815.1 1394369 1395553 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1394369..1395553 Bifidobacterium animalis subsp. lactis DSM 10140 8010830 YP_002970195.1 CDS Balat_1210 NC_012815.1 1395610 1396056 R COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR complement(1395610..1396056) Bifidobacterium animalis subsp. lactis DSM 10140 8010831 YP_002970196.1 CDS Balat_1211 NC_012815.1 1396151 1396582 R COG1388 FOG: LysM repeat; hypothetical protein complement(1396151..1396582) Bifidobacterium animalis subsp. lactis DSM 10140 8010832 YP_002970197.1 CDS Balat_1212 NC_012815.1 1396639 1397334 D Represses a number of genes involved in the response to DNA damage; LexA repressor 1396639..1397334 Bifidobacterium animalis subsp. lactis DSM 10140 8010833 YP_002970198.1 CDS Balat_1213 NC_012815.1 1397717 1398649 R COG1230 Co/Zn/Cd efflux system component; cation efflux protein complement(1397717..1398649) Bifidobacterium animalis subsp. lactis DSM 10140 8010834 YP_002970199.1 CDS Balat_1214 NC_012815.1 1398763 1399725 R COG0039 Malate/lactate dehydrogenases; L-lactate dehydrogenase 2 complement(1398763..1399725) Bifidobacterium animalis subsp. lactis DSM 10140 8010835 YP_002970200.1 CDS Balat_1215 NC_012815.1 1399900 1401447 R COG2262 GTPases; GTP-binding protein complement(1399900..1401447) Bifidobacterium animalis subsp. lactis DSM 10140 8010836 YP_002970201.1 CDS Balat_1216 NC_012815.1 1401551 1402180 D COG2813 16S RNA G1207 methylase RsmC; hypothetical protein 1401551..1402180 Bifidobacterium animalis subsp. lactis DSM 10140 8010837 YP_002970202.1 CDS Balat_1217 NC_012815.1 1402224 1406270 D COG1643 HrpA-like helicases; ATP-dependent helicase 1402224..1406270 Bifidobacterium animalis subsp. lactis DSM 10140 8010838 YP_002970203.1 CDS Balat_1218 NC_012815.1 1406364 1407701 R COG0174 Glutamine synthetase; glutamine synthetase 2 complement(1406364..1407701) Bifidobacterium animalis subsp. lactis DSM 10140 8010839 YP_002970204.1 CDS Balat_1219 NC_012815.1 1407882 1409285 D COG4320 Uncharacterized protein conserved in bacteria; hypothetical protein 1407882..1409285 Bifidobacterium animalis subsp. lactis DSM 10140 8010840 YP_002970205.1 CDS Balat_1220 NC_012815.1 1409405 1410133 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A complement(1409405..1410133) Bifidobacterium animalis subsp. lactis DSM 10140 8010841 YP_002970206.1 CDS hisH NC_012815.1 1410181 1410828 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(1410181..1410828) Bifidobacterium animalis subsp. lactis DSM 10140 8010842 YP_002970207.1 CDS Balat_1222 NC_012815.1 1410859 1411608 R hypothetical protein complement(1410859..1411608) Bifidobacterium animalis subsp. lactis DSM 10140 8010843 YP_002970208.1 CDS hisB NC_012815.1 1411608 1412210 R catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase complement(1411608..1412210) Bifidobacterium animalis subsp. lactis DSM 10140 8010844 YP_002970209.1 CDS Balat_1224 NC_012815.1 1412253 1413419 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1412253..1413419) Bifidobacterium animalis subsp. lactis DSM 10140 8010845 YP_002970210.1 CDS hisD NC_012815.1 1413416 1414798 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(1413416..1414798) Bifidobacterium animalis subsp. lactis DSM 10140 8010846 YP_002970211.1 CDS dnaE NC_012815.1 1415098 1418664 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(1415098..1418664) Bifidobacterium animalis subsp. lactis DSM 10140 8010847 YP_002970212.1 CDS Balat_1227 NC_012815.1 1418866 1419171 D hypothetical protein 1418866..1419171 Bifidobacterium animalis subsp. lactis DSM 10140 8010848 YP_002970213.1 CDS Balat_1228 NC_012815.1 1419151 1420104 R COG0564 Pseudouridylate synthases, 23SRNA-specific; hypothetical protein complement(1419151..1420104) Bifidobacterium animalis subsp. lactis DSM 10140 8010849 YP_002970214.1 CDS Balat_1229 NC_012815.1 1420123 1420629 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(1420123..1420629) Bifidobacterium animalis subsp. lactis DSM 10140 8010850 YP_002970215.1 CDS Balat_1230 NC_012815.1 1420678 1422144 R COG3599 Cell division initiation protein; hypothetical protein complement(1420678..1422144) Bifidobacterium animalis subsp. lactis DSM 10140 8010851 YP_002970216.1 CDS Balat_1231 NC_012815.1 1422321 1422611 R COG0762 Predicted integral membrane protein; hypothetical protein complement(1422321..1422611) Bifidobacterium animalis subsp. lactis DSM 10140 8010852 YP_002970217.1 CDS Balat_1232 NC_012815.1 1422693 1423163 R COG1799 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1422693..1423163) Bifidobacterium animalis subsp. lactis DSM 10140 8010853 YP_002970218.1 CDS Balat_1233 NC_012815.1 1423252 1424508 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1423252..1424508) Bifidobacterium animalis subsp. lactis DSM 10140 8010854 YP_002970219.1 CDS Balat_1234 NC_012815.1 1424669 1425922 R COG0042 tRNA-dihydrouridine synthase; NifR3-like protein complement(1424669..1425922) Bifidobacterium animalis subsp. lactis DSM 10140 8010855 YP_002970220.1 CDS Balat_1235 NC_012815.1 1426053 1427528 R Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase complement(1426053..1427528) Bifidobacterium animalis subsp. lactis DSM 10140 8010856 YP_002970221.1 CDS Balat_1236 NC_012815.1 1427770 1428681 D COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 1427770..1428681 Bifidobacterium animalis subsp. lactis DSM 10140 8010857 YP_002970222.1 CDS Balat_1237 NC_012815.1 1428734 1430284 D COG0352 Thiamine monophosphate synthase; phosphomethylpyrimidine kinase 1428734..1430284 Bifidobacterium animalis subsp. lactis DSM 10140 8010858 YP_002970223.1 CDS Balat_1238 NC_012815.1 1430373 1430741 D COG0011 Uncharacterized conserved protein; hypothetical protein 1430373..1430741 Bifidobacterium animalis subsp. lactis DSM 10140 8010859 YP_002970224.1 CDS Balat_1239 NC_012815.1 1430815 1431873 D COG1609 Transcriptional regulators; LacI-type transcriptional regulator 1430815..1431873 Bifidobacterium animalis subsp. lactis DSM 10140 8010860 YP_002970225.1 CDS lacY NC_012815.1 1432171 1433496 D lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 1432171..1433496 Bifidobacterium animalis subsp. lactis DSM 10140 8010861 YP_002970226.1 CDS Balat_1241 NC_012815.1 1433747 1435345 D COG1621 Beta-fructosidases (levanase/invertase); Sucrose-6-phosphate hydrolase 1433747..1435345 Bifidobacterium animalis subsp. lactis DSM 10140 8010862 YP_002970227.1 CDS Balat_1242 NC_012815.1 1435564 1436376 D COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 1435564..1436376 Bifidobacterium animalis subsp. lactis DSM 10140 8010863 YP_002970228.1 CDS Balat_1243 NC_012815.1 1436421 1437503 D COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; ABC transporter substrate-binding protein 1436421..1437503 Bifidobacterium animalis subsp. lactis DSM 10140 8010864 YP_002970229.1 CDS Balat_1244 NC_012815.1 1437555 1438790 D COG1957 Inosine-uridine nucleoside N-ribohydrolase; Inosine-uridine nucleoside N-ribohydrolase 1437555..1438790 Bifidobacterium animalis subsp. lactis DSM 10140 8010865 YP_002970230.1 CDS Balat_1245 NC_012815.1 1438796 1438969 R hypothetical protein complement(1438796..1438969) Bifidobacterium animalis subsp. lactis DSM 10140 8010866 YP_002970231.1 CDS Balat_1246 NC_012815.1 1439176 1439967 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(1439176..1439967) Bifidobacterium animalis subsp. lactis DSM 10140 8010867 YP_002970232.1 CDS recO NC_012815.1 1439972 1440691 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(1439972..1440691) Bifidobacterium animalis subsp. lactis DSM 10140 8010868 YP_002970233.1 CDS Balat_1248 NC_012815.1 1440704 1442422 R COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein complement(1440704..1442422) Bifidobacterium animalis subsp. lactis DSM 10140 8010869 YP_002970234.1 CDS ispG NC_012815.1 1442438 1443640 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(1442438..1443640) Bifidobacterium animalis subsp. lactis DSM 10140 8010870 YP_002970235.1 CDS Balat_1250 NC_012815.1 1443761 1444951 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(1443761..1444951) Bifidobacterium animalis subsp. lactis DSM 10140 8010871 YP_002970236.1 CDS Balat_1251 NC_012815.1 1445004 1446605 R hypothetical protein complement(1445004..1446605) Bifidobacterium animalis subsp. lactis DSM 10140 8010872 YP_002970237.1 CDS Balat_1253 NC_012815.1 1446975 1447466 D COG1196 Chromosome segregation ATPases; hypothetical protein 1446975..1447466 Bifidobacterium animalis subsp. lactis DSM 10140 8010874 YP_002970238.1 CDS Balat_1254 NC_012815.1 1447589 1448005 R COG2303 Choline dehydrogenase and related flavoproteins; hypothetical protein complement(1447589..1448005) Bifidobacterium animalis subsp. lactis DSM 10140 8010875 YP_002970239.1 CDS Balat_1255 NC_012815.1 1448111 1449067 R COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein complement(1448111..1449067) Bifidobacterium animalis subsp. lactis DSM 10140 8010876 YP_002970240.1 CDS Balat_1256 NC_012815.1 1449172 1450830 D COG5282 Uncharacterized conserved protein; hypothetical protein 1449172..1450830 Bifidobacterium animalis subsp. lactis DSM 10140 8010877 YP_002970241.1 CDS Balat_1257 NC_012815.1 1450916 1452505 R COG0210 Superfamily I DNA and RNA helicases; DNA helicase II complement(1450916..1452505) Bifidobacterium animalis subsp. lactis DSM 10140 8010878 YP_002970242.1 CDS Balat_1258 NC_012815.1 1452673 1454154 D COG3173 Predicted aminoglycosidephosphotransferase; hypothetical protein 1452673..1454154 Bifidobacterium animalis subsp. lactis DSM 10140 8010879 YP_002970243.1 CDS Balat_1259 NC_012815.1 1454272 1454499 D hypothetical protein 1454272..1454499 Bifidobacterium animalis subsp. lactis DSM 10140 8010880 YP_002970244.1 CDS Balat_1260 NC_012815.1 1454590 1455474 R COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein complement(1454590..1455474) Bifidobacterium animalis subsp. lactis DSM 10140 8010881 YP_002970245.1 CDS Balat_1261 NC_012815.1 1455650 1456318 D COG4243 Predicted membrane protein; hypothetical protein 1455650..1456318 Bifidobacterium animalis subsp. lactis DSM 10140 8010882 YP_002970246.1 CDS Balat_1262 NC_012815.1 1456342 1457226 R COG0253 Diaminopimelate epimerase; diaminopimelate epimerase complement(1456342..1457226) Bifidobacterium animalis subsp. lactis DSM 10140 8010883 YP_002970247.1 CDS Balat_1263 NC_012815.1 1457366 1458142 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1457366..1458142 Bifidobacterium animalis subsp. lactis DSM 10140 8010884 YP_002970248.1 CDS Balat_1264 NC_012815.1 1458192 1459049 D COG4667 Predicted esterase of the alpha-betahydrolase superfamily; hypothetical protein 1458192..1459049 Bifidobacterium animalis subsp. lactis DSM 10140 8010885 YP_002970249.1 CDS Balat_1265 NC_012815.1 1459125 1460033 R COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein complement(1459125..1460033) Bifidobacterium animalis subsp. lactis DSM 10140 8010886 YP_002970250.1 CDS Balat_1266 NC_012815.1 1460265 1461173 R COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter substrate-binding protein complement(1460265..1461173) Bifidobacterium animalis subsp. lactis DSM 10140 8010887 YP_002970251.1 CDS Balat_1267 NC_012815.1 1461222 1462115 R COG1126 ABC-type polar amino acid transport system, ATPase component; glutamate/aspartate ABC transporter ATP binding protein complement(1461222..1462115) Bifidobacterium animalis subsp. lactis DSM 10140 8010888 YP_002970252.1 CDS Balat_1268 NC_012815.1 1462108 1462782 R COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(1462108..1462782) Bifidobacterium animalis subsp. lactis DSM 10140 8010889 YP_002970253.1 CDS Balat_1269 NC_012815.1 1462769 1463425 R COG0765 ABC-type amino acid transport system, permease component; ABC transporter permease complement(1462769..1463425) Bifidobacterium animalis subsp. lactis DSM 10140 8010890 YP_002970254.1 CDS Balat_1270 NC_012815.1 1463597 1464781 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; transaminase complement(1463597..1464781) Bifidobacterium animalis subsp. lactis DSM 10140 8010891 YP_002970255.1 CDS Balat_1271 NC_012815.1 1465014 1465673 R COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter, permease complement(1465014..1465673) Bifidobacterium animalis subsp. lactis DSM 10140 8010892 YP_002970256.1 CDS Balat_1272 NC_012815.1 1465670 1466854 R COG1135 ABC-type metal ion transport system, ATPase component; ABC transporter ATP-binding protein complement(1465670..1466854) Bifidobacterium animalis subsp. lactis DSM 10140 8010893 YP_002970257.1 CDS Balat_1273 NC_012815.1 1466906 1467802 R COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; NLPA lipoprotein complement(1466906..1467802) Bifidobacterium animalis subsp. lactis DSM 10140 8010894 YP_002970258.1 CDS Balat_1274 NC_012815.1 1467917 1468927 R COG1893 Ketopantoate reductase; 2-dehydropantoate 2-reductase complement(1467917..1468927) Bifidobacterium animalis subsp. lactis DSM 10140 8010895 YP_002970259.1 CDS Balat_1275 NC_012815.1 1469279 1469938 D COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 1469279..1469938 Bifidobacterium animalis subsp. lactis DSM 10140 8010896 YP_002970260.1 CDS Balat_1276 NC_012815.1 1470192 1470758 D COG2176 DNA polymerase III, alpha subunit (gram-positive type); DNA polymerase III subunit alpha 1470192..1470758 Bifidobacterium animalis subsp. lactis DSM 10140 8010897 YP_002970261.1 CDS Balat_1282 NC_012815.1 1477713 1479683 R COG0480 Translation elongation factors (GTPases); translation elongation factor complement(1477713..1479683) Bifidobacterium animalis subsp. lactis DSM 10140 8010903 YP_002970262.1 CDS Balat_1283 NC_012815.1 1479713 1481248 R COG0531 Amino acid transporters; putative arginine/ornithine antiporter complement(1479713..1481248) Bifidobacterium animalis subsp. lactis DSM 10140 8010904 YP_002970263.1 CDS Balat_1284 NC_012815.1 1481351 1481980 R hypothetical protein complement(1481351..1481980) Bifidobacterium animalis subsp. lactis DSM 10140 8010905 YP_002970264.1 CDS Balat_1285 NC_012815.1 1482125 1482343 R hypothetical protein complement(1482125..1482343) Bifidobacterium animalis subsp. lactis DSM 10140 8010906 YP_002970265.1 CDS Balat_1286 NC_012815.1 1482644 1484314 D COG4166 ABC-type oligopeptide transport system, periplasmic component; ABC transporter 1482644..1484314 Bifidobacterium animalis subsp. lactis DSM 10140 8010907 YP_002970266.1 CDS Balat_1287 NC_012815.1 1484321 1485778 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1484321..1485778 Bifidobacterium animalis subsp. lactis DSM 10140 8010908 YP_002970267.1 CDS Balat_1288 NC_012815.1 1485885 1486583 R COG1842 Phage shock protein A (IM30, suppresses sigma54-dependent transcription); phage shock protein A-like protein complement(1485885..1486583) Bifidobacterium animalis subsp. lactis DSM 10140 8010909 YP_002970268.1 CDS Balat_1289 NC_012815.1 1486586 1487821 R hypothetical protein complement(1486586..1487821) Bifidobacterium animalis subsp. lactis DSM 10140 8010910 YP_002970269.1 CDS Balat_1290 NC_012815.1 1487994 1488215 R hypothetical protein complement(1487994..1488215) Bifidobacterium animalis subsp. lactis DSM 10140 8010911 YP_002970270.1 CDS ileS NC_012815.1 1488450 1491773 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(1488450..1491773) Bifidobacterium animalis subsp. lactis DSM 10140 8010912 YP_002970271.1 CDS Balat_1292 NC_012815.1 1492215 1492382 R hypothetical protein complement(1492215..1492382) Bifidobacterium animalis subsp. lactis DSM 10140 8010913 YP_002970272.1 CDS Balat_1293 NC_012815.1 1492565 1493335 R COG2365 Protein tyrosine/serine phosphatase; putative serine/tyrosine protein phosphatase complement(1492565..1493335) Bifidobacterium animalis subsp. lactis DSM 10140 8010914 YP_002970273.1 CDS Balat_1294 NC_012815.1 1493363 1493653 R hypothetical protein complement(1493363..1493653) Bifidobacterium animalis subsp. lactis DSM 10140 8010915 YP_002970274.1 CDS Balat_1295 NC_012815.1 1493892 1494104 R hypothetical protein complement(1493892..1494104) Bifidobacterium animalis subsp. lactis DSM 10140 8010916 YP_002970275.1 CDS Balat_1296 NC_012815.1 1494263 1496341 R COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter complement(1494263..1496341) Bifidobacterium animalis subsp. lactis DSM 10140 8010917 YP_002970276.1 CDS Balat_1297 NC_012815.1 1496338 1498311 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1496338..1498311) Bifidobacterium animalis subsp. lactis DSM 10140 8010918 YP_002970277.1 CDS Balat_1298 NC_012815.1 1498308 1498859 R COG1846 Transcriptional regulators; MarR family transcriptional regulator complement(1498308..1498859) Bifidobacterium animalis subsp. lactis DSM 10140 8010919 YP_002970278.1 CDS Balat_1299 NC_012815.1 1499117 1499683 R COG0431 Predicted flavoprotein; NADPH-dependent reductase complement(1499117..1499683) Bifidobacterium animalis subsp. lactis DSM 10140 8010920 YP_002970279.1 CDS Balat_1300 NC_012815.1 1499926 1500309 D COG3727 DNA G:T-mismatch repair endonuclease; Vsr endonuclease 1499926..1500309 Bifidobacterium animalis subsp. lactis DSM 10140 8010921 YP_002970280.1 CDS Balat_1301 NC_012815.1 1501340 1501528 D hypothetical protein 1501340..1501528 Bifidobacterium animalis subsp. lactis DSM 10140 8010922 YP_002970281.1 CDS Balat_1302 NC_012815.1 1501891 1502151 D hypothetical protein 1501891..1502151 Bifidobacterium animalis subsp. lactis DSM 10140 8010923 YP_002970282.1 CDS csb3 NC_012815.1 1502222 1503268 R putative CRISPR-associated Csb3 family protein complement(1502222..1503268) Bifidobacterium animalis subsp. lactis DSM 10140 8010924 YP_002970283.1 CDS cas3 NC_012815.1 1503272 1506325 R COG1196 Chromosome segregation ATPases; CRISPR-associated helicase Cas3 family protein complement(1503272..1506325) Bifidobacterium animalis subsp. lactis DSM 10140 8010925 YP_002970284.1 CDS csb2 NC_012815.1 1506316 1507953 R putative CRISPR-associated Csb2 family protein complement(1506316..1507953) Bifidobacterium animalis subsp. lactis DSM 10140 8010926 YP_002970285.1 CDS csb1 NC_012815.1 1507972 1509165 R putative CRISPR-associated Csb1 family protein complement(1507972..1509165) Bifidobacterium animalis subsp. lactis DSM 10140 8010927 YP_002970286.1 CDS cas2 NC_012815.1 1509582 1509875 R COG1343 Uncharacterized protein predicted to beinvolved in DNA repair; CRISPR-associated Cas2 family protein complement(1509582..1509875) Bifidobacterium animalis subsp. lactis DSM 10140 8010928 YP_002970287.1 CDS cas1 NC_012815.1 1509887 1511377 R COG1518; COG1468 RecB family exonuclease/transl_table; CRISPR-associated Cas1/Cas4 family protein complement(1509887..1511377) Bifidobacterium animalis subsp. lactis DSM 10140 8010929 YP_002970288.1 CDS Balat_1309 NC_012815.1 1513131 1514282 R COG3572 Gamma-glutamylcysteine synthetase; Gamma-glutamylcysteine synthetase complement(1513131..1514282) Bifidobacterium animalis subsp. lactis DSM 10140 8010930 YP_002970289.1 CDS Balat_1310 NC_012815.1 1514476 1519194 R COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); hypothetical protein complement(1514476..1519194) Bifidobacterium animalis subsp. lactis DSM 10140 8010931 YP_002970290.1 CDS Balat_1311 NC_012815.1 1519444 1520013 D COG3548 Predicted integral membrane protein; hypothetical protein 1519444..1520013 Bifidobacterium animalis subsp. lactis DSM 10140 8010932 YP_002970291.1 CDS Balat_1312 NC_012815.1 1520010 1520411 D COG3759 Predicted membrane protein; transmembrane protein 1520010..1520411 Bifidobacterium animalis subsp. lactis DSM 10140 8010933 YP_002970292.1 CDS Balat_1313 NC_012815.1 1520674 1521363 D hypothetical protein 1520674..1521363 Bifidobacterium animalis subsp. lactis DSM 10140 8010934 YP_002970293.1 CDS Balat_1314 NC_012815.1 1521360 1522109 R COG0602 Organic radical activating enzymes; anaerobic ribonucleoside-triphosphate reductase activating protein complement(1521360..1522109) Bifidobacterium animalis subsp. lactis DSM 10140 8010935 YP_002970294.1 CDS Balat_1315 NC_012815.1 1522451 1524877 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(1522451..1524877) Bifidobacterium animalis subsp. lactis DSM 10140 8010936 YP_002970295.1 CDS xseA NC_012815.1 1525234 1526532 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1525234..1526532 Bifidobacterium animalis subsp. lactis DSM 10140 8010937 YP_002970296.1 CDS Balat_1317 NC_012815.1 1526576 1526893 D COG1722 Exonuclease VII small subunit; exonuclease VII small subunit 1526576..1526893 Bifidobacterium animalis subsp. lactis DSM 10140 8010938 YP_002970297.1 CDS Balat_1318 NC_012815.1 1526894 1527919 R COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1526894..1527919) Bifidobacterium animalis subsp. lactis DSM 10140 8010939 YP_002970298.1 CDS Balat_1320 NC_012815.1 1528272 1529000 D hypothetical protein 1528272..1529000 Bifidobacterium animalis subsp. lactis DSM 10140 8010941 YP_002970299.1 CDS Balat_1321 NC_012815.1 1529016 1530245 R COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate aminotransferase complement(1529016..1530245) Bifidobacterium animalis subsp. lactis DSM 10140 8010942 YP_002970300.1 CDS Balat_1322 NC_012815.1 1530271 1530804 R COG3727 DNA G:T-mismatch repair endonuclease; XorII very-short-patch-repair endonuclease complement(1530271..1530804) Bifidobacterium animalis subsp. lactis DSM 10140 8010943 YP_002970301.1 CDS Balat_1323 NC_012815.1 1530921 1532489 D hypothetical protein 1530921..1532489 Bifidobacterium animalis subsp. lactis DSM 10140 8010944 YP_002970302.1 CDS Balat_1324 NC_012815.1 1532523 1533908 R COG0847 DNA polymerase III, epsilon subunit and related 3-5 exonucleases; DNA polymerase III subunit epsilon complement(1532523..1533908) Bifidobacterium animalis subsp. lactis DSM 10140 8010945 YP_002970303.1 CDS def NC_012815.1 1534046 1534699 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1534046..1534699) Bifidobacterium animalis subsp. lactis DSM 10140 8010946 YP_002970304.1 CDS glmM NC_012815.1 1534737 1536107 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1534737..1536107) Bifidobacterium animalis subsp. lactis DSM 10140 8010947 YP_002970305.1 CDS Balat_1327 NC_012815.1 1536566 1539190 R COG0308 Aminopeptidase N; aminopeptidase complement(1536566..1539190) Bifidobacterium animalis subsp. lactis DSM 10140 8010948 YP_002970306.1 CDS Balat_1328 NC_012815.1 1539347 1541254 R COG0595 Predicted hydrolase of themetallo-beta-lactamase superfamily; hypothetical protein complement(1539347..1541254) Bifidobacterium animalis subsp. lactis DSM 10140 8010949 YP_002970307.1 CDS Balat_1329 NC_012815.1 1541355 1542251 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(1541355..1542251) Bifidobacterium animalis subsp. lactis DSM 10140 8010950 YP_002970308.1 CDS Balat_1330 NC_012815.1 1542312 1543073 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(1542312..1543073) Bifidobacterium animalis subsp. lactis DSM 10140 8010951 YP_002970309.1 CDS Balat_1331 NC_012815.1 1543129 1544547 R COG0477 Permeases of the major facilitator superfamily; transport protein complement(1543129..1544547) Bifidobacterium animalis subsp. lactis DSM 10140 8010952 YP_002970310.1 CDS Balat_1332 NC_012815.1 1544544 1545254 R COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetylglutamate synthase complement(1544544..1545254) Bifidobacterium animalis subsp. lactis DSM 10140 8010953 YP_002970311.1 CDS Balat_1333 NC_012815.1 1545477 1549613 R COG0210 Superfamily I DNA and RNA helicases; ATP-dependent DNA helicase complement(1545477..1549613) Bifidobacterium animalis subsp. lactis DSM 10140 8010954 YP_002970312.1 CDS Balat_1334 NC_012815.1 1549626 1554179 R COG0210 Superfamily I DNA and RNA helicases; hypothetical protein complement(1549626..1554179) Bifidobacterium animalis subsp. lactis DSM 10140 8010955 YP_002970313.1 CDS Balat_1335 NC_012815.1 1554514 1555917 D COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 1554514..1555917 Bifidobacterium animalis subsp. lactis DSM 10140 8010956 YP_002970314.1 CDS Balat_1336 NC_012815.1 1555924 1561845 D COG2931 RTX toxins and related Ca2+-binding proteins; fibronectin type III 1555924..1561845 Bifidobacterium animalis subsp. lactis DSM 10140 8010957 YP_002970315.1 CDS Balat_1337 NC_012815.1 1561829 1563067 D COG0714 MoxR-like ATPases; methanol dehydrogenase regulatory protein 1561829..1563067 Bifidobacterium animalis subsp. lactis DSM 10140 8010958 YP_002970316.1 CDS Balat_1338 NC_012815.1 1563054 1564247 D COG1721 Uncharacterized conserved protein (somemembers contain a von Willebrand factor type A (vWAdomain)); hypothetical protein 1563054..1564247 Bifidobacterium animalis subsp. lactis DSM 10140 8010959 YP_002970317.1 CDS Balat_1339 NC_012815.1 1564244 1566733 D COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 1564244..1566733 Bifidobacterium animalis subsp. lactis DSM 10140 8010960 YP_002970318.1 CDS Balat_1340 NC_012815.1 1567000 1567647 D hypothetical protein 1567000..1567647 Bifidobacterium animalis subsp. lactis DSM 10140 8010961 YP_002970319.1 CDS Balat_1341 NC_012815.1 1567662 1568288 R COG1716 FOG: FHA domain; hypothetical protein complement(1567662..1568288) Bifidobacterium animalis subsp. lactis DSM 10140 8010962 YP_002970320.1 CDS Balat_1342 NC_012815.1 1568408 1572445 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1568408..1572445) Bifidobacterium animalis subsp. lactis DSM 10140 8010963 YP_002970321.1 CDS rpoB NC_012815.1 1572506 1576066 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1572506..1576066) Bifidobacterium animalis subsp. lactis DSM 10140 8010964 YP_002970322.1 CDS Balat_1344 NC_012815.1 1576300 1576965 R hypothetical protein complement(1576300..1576965) Bifidobacterium animalis subsp. lactis DSM 10140 8010965 YP_002970323.1 CDS Balat_1345 NC_012815.1 1577282 1578271 R COG1194 A/G-specific DNA glycosylase; A/G-specific adenine glycosylase complement(1577282..1578271) Bifidobacterium animalis subsp. lactis DSM 10140 8010966 YP_002970324.1 CDS Balat_1346 NC_012815.1 1578345 1579016 D COG0219 Predicted rRNA methylase (SpoU class)); hypothetical protein 1578345..1579016 Bifidobacterium animalis subsp. lactis DSM 10140 8010967 YP_002970325.1 CDS Balat_1347 NC_012815.1 1579141 1580505 R COG2848 Uncharacterized conserved protein; hypothetical protein complement(1579141..1580505) Bifidobacterium animalis subsp. lactis DSM 10140 8010968 YP_002970326.1 CDS Balat_1348 NC_012815.1 1580550 1580822 R ACT domain-containing protein; hypothetical protein complement(1580550..1580822) Bifidobacterium animalis subsp. lactis DSM 10140 8010969 YP_002970327.1 CDS srtB NC_012815.1 1580947 1581795 R COG3764 Sortase (surface protein transpeptidase); sortase family protein complement(1580947..1581795) Bifidobacterium animalis subsp. lactis DSM 10140 8010970 YP_002970328.1 CDS Balat_1350 NC_012815.1 1581818 1581910 R hypothetical protein complement(1581818..1581910) Bifidobacterium animalis subsp. lactis DSM 10140 8010971 YP_002970329.1 CDS Balat_1351 NC_012815.1 1582076 1583326 R COG0153 Galactokinase; galactokinase complement(1582076..1583326) Bifidobacterium animalis subsp. lactis DSM 10140 8010972 YP_002970330.1 CDS Balat_1352 NC_012815.1 1583393 1584673 R COG1085 Galactose-1-phosphate uridylyltransferase; Galactose-1-phosphate uridylyltransferase complement(1583393..1584673) Bifidobacterium animalis subsp. lactis DSM 10140 8010973 YP_002970331.1 CDS Balat_1353 NC_012815.1 1584673 1585494 R COG1349 Transcriptional regulators of sugar metabolism; DeoR-type transcriptional regulator complement(1584673..1585494) Bifidobacterium animalis subsp. lactis DSM 10140 8010974 YP_002970332.1 CDS Balat_1354 NC_012815.1 1585612 1586643 R COG0463 Glycosyltransferases involved in cell wall biogenesis; dolichyl-phosphate beta-D-mannosyltransferase complement(1585612..1586643) Bifidobacterium animalis subsp. lactis DSM 10140 8010975 YP_002970333.1 CDS Balat_1355 NC_012815.1 1586806 1587966 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1586806..1587966 Bifidobacterium animalis subsp. lactis DSM 10140 8010976 YP_002970334.1 CDS Balat_1356 NC_012815.1 1588265 1589395 R COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; NADH-dependent flavin oxidoreductase YqjM complement(1588265..1589395) Bifidobacterium animalis subsp. lactis DSM 10140 8010977 YP_002970335.1 CDS Balat_1357 NC_012815.1 1589688 1591892 R COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase complement(1589688..1591892) Bifidobacterium animalis subsp. lactis DSM 10140 8010978 YP_002970336.1 CDS Balat_1358 NC_012815.1 1592023 1592784 R COG0664 cAMP-binding proteins - catabolite geneactivator and regulatory subunit of cAMP-dependent protein kinases; transcriptional regulator complement(1592023..1592784) Bifidobacterium animalis subsp. lactis DSM 10140 8010979 YP_002970337.1 CDS Balat_1359 NC_012815.1 1592824 1593987 R COG0095 Lipoate-protein ligase A; lipoate protein ligase complement(1592824..1593987) Bifidobacterium animalis subsp. lactis DSM 10140 8010980 YP_002970338.1 CDS Balat_1360 NC_012815.1 1594084 1594548 R COG2314 Predicted membrane protein; hypothetical protein complement(1594084..1594548) Bifidobacterium animalis subsp. lactis DSM 10140 8010981 YP_002970339.1 CDS Balat_1361 NC_012815.1 1594920 1595054 R hypothetical protein complement(1594920..1595054) Bifidobacterium animalis subsp. lactis DSM 10140 8010982 YP_002970340.1 CDS Balat_1362 NC_012815.1 1595130 1596170 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(1595130..1596170) Bifidobacterium animalis subsp. lactis DSM 10140 8010983 YP_002970341.1 CDS Balat_1363 NC_012815.1 1596338 1598731 R COG1770 Protease II; protease II complement(1596338..1598731) Bifidobacterium animalis subsp. lactis DSM 10140 8010984 YP_002970342.1 CDS Balat_1364 NC_012815.1 1598959 1600470 R COG4850 Uncharacterized conserved protein; hypothetical protein complement(1598959..1600470) Bifidobacterium animalis subsp. lactis DSM 10140 8010985 YP_002970343.1 CDS Balat_1365 NC_012815.1 1600527 1600937 R COG0509 Glycine cleavage system H protein (lipoate-binding); glycine cleavage system H protein complement(1600527..1600937) Bifidobacterium animalis subsp. lactis DSM 10140 8010986 YP_002970344.1 CDS Balat_1366 NC_012815.1 1601001 1602110 R COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; hypothetical protein complement(1601001..1602110) Bifidobacterium animalis subsp. lactis DSM 10140 8010987 YP_002970345.1 CDS Balat_1367 NC_012815.1 1602110 1603036 R COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha beta hydrolase complement(1602110..1603036) Bifidobacterium animalis subsp. lactis DSM 10140 8010988 YP_002970346.1 CDS Balat_1368 NC_012815.1 1603116 1603730 R hypothetical protein complement(1603116..1603730) Bifidobacterium animalis subsp. lactis DSM 10140 8010989 YP_002970347.1 CDS Balat_1369 NC_012815.1 1603916 1604311 D COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 1603916..1604311 Bifidobacterium animalis subsp. lactis DSM 10140 8010990 YP_002970348.1 CDS Balat_1370 NC_012815.1 1604612 1605670 D COG3583 Uncharacterized protein conserved in bacteria; hypothetical protein 1604612..1605670 Bifidobacterium animalis subsp. lactis DSM 10140 8010991 YP_002970349.1 CDS Balat_1371 NC_012815.1 1605947 1607557 R COG2148 Sugar transferases involved inlipopolysaccharide synthesis; UDP-phosphate sugar phosphotransferase complement(1605947..1607557) Bifidobacterium animalis subsp. lactis DSM 10140 8010992 YP_002970350.1 CDS Balat_1372 NC_012815.1 1607820 1608269 R hypothetical protein complement(1607820..1608269) Bifidobacterium animalis subsp. lactis DSM 10140 8010993 YP_002970351.1 CDS Balat_1373 NC_012815.1 1608681 1610120 D COG4713 Predicted membrane protein; hypothetical protein 1608681..1610120 Bifidobacterium animalis subsp. lactis DSM 10140 8010994 YP_002970352.1 CDS Balat_1374 NC_012815.1 1610104 1611045 R COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase complement(1610104..1611045) Bifidobacterium animalis subsp. lactis DSM 10140 8010995 YP_002970353.1 CDS Balat_1375 NC_012815.1 1611189 1612856 R hypothetical protein complement(1611189..1612856) Bifidobacterium animalis subsp. lactis DSM 10140 8010996 YP_002970354.1 CDS Balat_1376 NC_012815.1 1613222 1614112 R COG1209 dTDP-glucose pyrophosphorylase; dTDP-glucose pyrophosphorylase complement(1613222..1614112) Bifidobacterium animalis subsp. lactis DSM 10140 8010997 YP_002970355.1 CDS Balat_1377 NC_012815.1 1614126 1615577 R COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes; dTDP-4-dehydrorhamnose 3,5-epimerase complement(1614126..1615577) Bifidobacterium animalis subsp. lactis DSM 10140 8010998 YP_002970356.1 CDS Balat_1378 NC_012815.1 1615652 1616671 R COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-D-glucose 4,6-dehydratase complement(1615652..1616671) Bifidobacterium animalis subsp. lactis DSM 10140 8010999 YP_002970357.1 CDS Balat_1379 NC_012815.1 1616827 1617792 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase-like protein 1616827..1617792 Bifidobacterium animalis subsp. lactis DSM 10140 8011000 YP_002970358.1 CDS Balat_1380 NC_012815.1 1617794 1619245 R COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx complement(1617794..1619245) Bifidobacterium animalis subsp. lactis DSM 10140 8011001 YP_002970359.1 CDS Balat_1381 NC_012815.1 1619271 1620158 R COG1216 Predicted glycosyltransferases; glycosyl transferase family protein complement(1619271..1620158) Bifidobacterium animalis subsp. lactis DSM 10140 8011002 YP_002970360.1 CDS Balat_1382 NC_012815.1 1620177 1621190 R COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase complement(1620177..1621190) Bifidobacterium animalis subsp. lactis DSM 10140 8011003 YP_002970361.1 CDS Balat_1383 NC_012815.1 1621183 1622529 R hypothetical protein complement(1621183..1622529) Bifidobacterium animalis subsp. lactis DSM 10140 8011004 YP_002970362.1 CDS Balat_1384 NC_012815.1 1622526 1623419 R COG1216 Predicted glycosyltransferases; glycosyltransferase complement(1622526..1623419) Bifidobacterium animalis subsp. lactis DSM 10140 8011005 YP_002970363.1 CDS Balat_1385 NC_012815.1 1623432 1624196 R hypothetical protein complement(1623432..1624196) Bifidobacterium animalis subsp. lactis DSM 10140 8011006 YP_002970364.1 CDS Balat_1386 NC_012815.1 1624201 1625088 R COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein complement(1624201..1625088) Bifidobacterium animalis subsp. lactis DSM 10140 8011007 YP_002970365.1 CDS Balat_1387 NC_012815.1 1625238 1626170 R polysaccharide biosynthesis protein complement(1625238..1626170) Bifidobacterium animalis subsp. lactis DSM 10140 8011008 YP_002970366.1 CDS Balat_1388 NC_012815.1 1626235 1627482 R COG1004 Predicted UDP-glucose 6-dehydrogenase; uridine diphosphate glucose dehydrogenase complement(1626235..1627482) Bifidobacterium animalis subsp. lactis DSM 10140 8011009 YP_002970367.1 CDS Balat_1389 NC_012815.1 1627603 1628937 R COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx complement(1627603..1628937) Bifidobacterium animalis subsp. lactis DSM 10140 8011010 YP_002970368.1 CDS Balat_1390 NC_012815.1 1629087 1630091 R hypothetical protein complement(1629087..1630091) Bifidobacterium animalis subsp. lactis DSM 10140 8011011 YP_002970369.1 CDS Balat_1391 NC_012815.1 1630144 1631007 R COG1216 Predicted glycosyltransferases; group 2 family glycosyl transferase complement(1630144..1631007) Bifidobacterium animalis subsp. lactis DSM 10140 8011012 YP_002970370.1 CDS Balat_1392 NC_012815.1 1631101 1632636 R COG2148 Sugar transferases involved inlipopolysaccharide synthesis; galactosyl transferase CpsD complement(1631101..1632636) Bifidobacterium animalis subsp. lactis DSM 10140 8011013 YP_002970371.1 CDS Balat_1393 NC_012815.1 1632913 1633254 D hypothetical protein 1632913..1633254 Bifidobacterium animalis subsp. lactis DSM 10140 8011014 YP_002970372.1 CDS Balat_1394 NC_012815.1 1633327 1635051 D COG0477 Permeases of the major facilitator superfamily; hypothetical protein 1633327..1635051 Bifidobacterium animalis subsp. lactis DSM 10140 8011015 YP_002970373.1 CDS Balat_1395 NC_012815.1 1635189 1636505 R COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; H(+)-stimulated manganese uptake system protein complement(1635189..1636505) Bifidobacterium animalis subsp. lactis DSM 10140 8011016 YP_002970374.1 CDS Balat_1396 NC_012815.1 1636651 1637379 R hypothetical protein complement(1636651..1637379) Bifidobacterium animalis subsp. lactis DSM 10140 8011017 YP_002970375.1 CDS Balat_1397 NC_012815.1 1637538 1638413 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1637538..1638413 Bifidobacterium animalis subsp. lactis DSM 10140 8011018 YP_002970376.1 CDS Balat_1398 NC_012815.1 1638440 1639090 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1638440..1639090 Bifidobacterium animalis subsp. lactis DSM 10140 8011019 YP_002970377.1 CDS Balat_1399 NC_012815.1 1639433 1640569 D COG0451 Nucleoside-diphosphate-sugar epimerases; nucleotide sugar epimerase 1639433..1640569 Bifidobacterium animalis subsp. lactis DSM 10140 8011020 YP_002970378.1 CDS Balat_1400 NC_012815.1 1640674 1641138 D COG0707 UDP-N-acetylglucosamine: LPSN-acetylglucosamine transferase; polysaccharide biosynthesis protein CpsF 1640674..1641138 Bifidobacterium animalis subsp. lactis DSM 10140 8011021 YP_002970379.1 CDS Balat_1401 NC_012815.1 1641138 1641638 D COG5017 Uncharacterized conserved protein; glycosyltransferase 28-like protein 1641138..1641638 Bifidobacterium animalis subsp. lactis DSM 10140 8011022 YP_002970380.1 CDS Balat_1402 NC_012815.1 1641716 1642669 D COG1216 Predicted glycosyltransferases; putative glycosyltransferase 1641716..1642669 Bifidobacterium animalis subsp. lactis DSM 10140 8011023 YP_002970381.1 CDS Balat_1403 NC_012815.1 1642662 1643498 D COG1216 Predicted glycosyltransferases; glycosyl transferase family protein 1642662..1643498 Bifidobacterium animalis subsp. lactis DSM 10140 8011024 YP_002970382.1 CDS Balat_1404 NC_012815.1 1643684 1644817 D hypothetical protein 1643684..1644817 Bifidobacterium animalis subsp. lactis DSM 10140 8011025 YP_002970383.1 CDS Balat_1405 NC_012815.1 1644942 1648523 R COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1644942..1648523) Bifidobacterium animalis subsp. lactis DSM 10140 8011026 YP_002970384.1 CDS Balat_1406 NC_012815.1 1648765 1650585 D COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain-fatty acid CoA ligase 1648765..1650585 Bifidobacterium animalis subsp. lactis DSM 10140 8011027 YP_002970385.1 CDS Balat_1407 NC_012815.1 1650660 1652048 R COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; hypothetical protein complement(1650660..1652048) Bifidobacterium animalis subsp. lactis DSM 10140 8011028 YP_002970386.1 CDS Balat_1408 NC_012815.1 1652236 1652802 D COG0394 Protein-tyrosine-phosphatase; hypothetical protein 1652236..1652802 Bifidobacterium animalis subsp. lactis DSM 10140 8011029 YP_002970387.1 CDS Balat_1409 NC_012815.1 1652887 1654656 R hypothetical protein complement(1652887..1654656) Bifidobacterium animalis subsp. lactis DSM 10140 8011030 YP_002970388.1 CDS Balat_1410 NC_012815.1 1654782 1656254 R COG3944 Capsular polysaccharide biosynthesis protein; Etk-like tyrosine kinase complement(1654782..1656254) Bifidobacterium animalis subsp. lactis DSM 10140 8011031 YP_002970389.1 CDS Balat_1411 NC_012815.1 1657143 1657997 D hypothetical protein 1657143..1657997 Bifidobacterium animalis subsp. lactis DSM 10140 8011032 YP_002970390.1 CDS Balat_1412 NC_012815.1 1658128 1658463 D hypothetical protein 1658128..1658463 Bifidobacterium animalis subsp. lactis DSM 10140 8011033 YP_002970391.1 CDS Balat_1413 NC_012815.1 1659063 1660196 D COG3464 Transposase and in activated derivatives; transposase, IS204/IS1001/IS1096/IS1165 family protein 1659063..1660196 Bifidobacterium animalis subsp. lactis DSM 10140 8011034 YP_002970392.1 CDS Balat_1414 NC_012815.1 1660759 1661742 R COG0083 Homoserine kinase; homoserine kinase complement(1660759..1661742) Bifidobacterium animalis subsp. lactis DSM 10140 8011035 YP_002970393.1 CDS Balat_1415 NC_012815.1 1661805 1663115 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1661805..1663115) Bifidobacterium animalis subsp. lactis DSM 10140 8011036 YP_002970394.1 CDS Balat_1416 NC_012815.1 1663388 1664977 R COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase complement(1663388..1664977) Bifidobacterium animalis subsp. lactis DSM 10140 8011037 YP_002970395.1 CDS argS NC_012815.1 1665172 1666944 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(1665172..1666944) Bifidobacterium animalis subsp. lactis DSM 10140 8011038 YP_002970396.1 CDS Balat_1418 NC_012815.1 1667208 1668662 R COG5520 O-Glycosyl hydrolase; glucan endo-1,6-beta-glucosidase complement(1667208..1668662) Bifidobacterium animalis subsp. lactis DSM 10140 8011039 YP_002970397.1 CDS Balat_1419 NC_012815.1 1668730 1669128 R COG0251 Putative translation initiation inhibitor, yjgF family; putative translation initiation inhibitor complement(1668730..1669128) Bifidobacterium animalis subsp. lactis DSM 10140 8011040 YP_002970398.1 CDS Balat_1420 NC_012815.1 1669376 1670074 R COG0395 ABC-type sugar transport system, permease component; putative sugar transport integral membrane protein complement(1669376..1670074) Bifidobacterium animalis subsp. lactis DSM 10140 8011041 YP_002970399.1 CDS Balat_1421 NC_012815.1 1670073 1670972 D COG3459 Cellobiose phosphorylase; hypothetical protein 1670073..1670972 Bifidobacterium animalis subsp. lactis DSM 10140 8011042 YP_002970400.1 CDS Balat_1423 NC_012815.1 1671307 1672260 R COG3118 Thioredoxin domain-containing protein; hypothetical protein complement(1671307..1672260) Bifidobacterium animalis subsp. lactis DSM 10140 8011044 YP_002970401.1 CDS Balat_1424 NC_012815.1 1672327 1673337 R hypothetical protein complement(1672327..1673337) Bifidobacterium animalis subsp. lactis DSM 10140 8011045 YP_002970402.1 CDS Balat_1425 NC_012815.1 1673334 1674683 R hypothetical protein complement(1673334..1674683) Bifidobacterium animalis subsp. lactis DSM 10140 8011046 YP_002970403.1 CDS Balat_1426 NC_012815.1 1674818 1675747 D COG0545 FKBP-type peptidyl-prolyl cis-transisomerases 1; secreted peptidyl-prolyl cis-trans isomeraseprotein 1674818..1675747 Bifidobacterium animalis subsp. lactis DSM 10140 8011047 YP_002970404.1 CDS Balat_1427 NC_012815.1 1675838 1676542 R COG1637 Predicted nuclease of the RecB family; hypothetical protein complement(1675838..1676542) Bifidobacterium animalis subsp. lactis DSM 10140 8011048 YP_002970405.1 CDS atpC NC_012815.1 1676967 1677275 R produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit epsilon complement(1676967..1677275) Bifidobacterium animalis subsp. lactis DSM 10140 8011049 YP_002970406.1 CDS Balat_1429 NC_012815.1 1677275 1678762 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(1677275..1678762) Bifidobacterium animalis subsp. lactis DSM 10140 8011050 YP_002970407.1 CDS Balat_1430 NC_012815.1 1678772 1679692 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(1678772..1679692) Bifidobacterium animalis subsp. lactis DSM 10140 8011051 YP_002970408.1 CDS Balat_1431 NC_012815.1 1679696 1681336 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(1679696..1681336) Bifidobacterium animalis subsp. lactis DSM 10140 8011052 YP_002970409.1 CDS Balat_1432 NC_012815.1 1681400 1682212 R produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(1681400..1682212) Bifidobacterium animalis subsp. lactis DSM 10140 8011053 YP_002970410.1 CDS Balat_1433 NC_012815.1 1682291 1682818 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(1682291..1682818) Bifidobacterium animalis subsp. lactis DSM 10140 8011054 YP_002970411.1 CDS Balat_1434 NC_012815.1 1682872 1683102 R COG0636 F0F1-type ATP synthase, subunitc/Archaeal/vacuolar-type H+-ATPase, subunit K; ATP synthase C chain complement(1682872..1683102) Bifidobacterium animalis subsp. lactis DSM 10140 8011055 YP_002970412.1 CDS Balat_1435 NC_012815.1 1683154 1683966 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(1683154..1683966) Bifidobacterium animalis subsp. lactis DSM 10140 8011056 YP_002970413.1 CDS Balat_1436 NC_012815.1 1684258 1685286 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1684258..1685286) Bifidobacterium animalis subsp. lactis DSM 10140 8011057 YP_002970414.1 CDS Balat_1437 NC_012815.1 1685407 1686837 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(1685407..1686837) Bifidobacterium animalis subsp. lactis DSM 10140 8011058 YP_002970415.1 CDS Balat_1438 NC_012815.1 1686951 1687892 R COG1957 Inosine-uridine nucleoside N-ribohydrolase; hypothetical protein complement(1686951..1687892) Bifidobacterium animalis subsp. lactis DSM 10140 8011059 YP_002970416.1 CDS Balat_1440 NC_012815.1 1688328 1689446 R hypothetical protein complement(1688328..1689446) Bifidobacterium animalis subsp. lactis DSM 10140 8011061 YP_002970417.1 CDS Balat_1441 NC_012815.1 1689606 1689791 D hypothetical protein 1689606..1689791 Bifidobacterium animalis subsp. lactis DSM 10140 8011062 YP_002970418.1 CDS Balat_1442 NC_012815.1 1689898 1690293 D hypothetical protein 1689898..1690293 Bifidobacterium animalis subsp. lactis DSM 10140 8011063 YP_002970419.1 CDS Balat_1443 NC_012815.1 1690290 1691051 D COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division FtsK/SpoIIIE 1690290..1691051 Bifidobacterium animalis subsp. lactis DSM 10140 8011064 YP_002970420.1 CDS Balat_1444 NC_012815.1 1691048 1691965 D COG1536 Flagellar motor switch protein; hypothetical protein 1691048..1691965 Bifidobacterium animalis subsp. lactis DSM 10140 8011065 YP_002970421.1 CDS Balat_1445 NC_012815.1 1691949 1692176 D hypothetical protein 1691949..1692176 Bifidobacterium animalis subsp. lactis DSM 10140 8011066 YP_002970422.1 CDS Balat_1446 NC_012815.1 1692196 1693314 R COG1479 Uncharacterized conserved protein; hypothetical protein complement(1692196..1693314) Bifidobacterium animalis subsp. lactis DSM 10140 8011067 YP_002970423.1 CDS Balat_1447 NC_012815.1 1693314 1694405 R modification methylase complement(1693314..1694405) Bifidobacterium animalis subsp. lactis DSM 10140 8011068 YP_002970424.1 CDS Balat_1448 NC_012815.1 1694483 1695703 R COG0582 Integrase; hypothetical protein complement(1694483..1695703) Bifidobacterium animalis subsp. lactis DSM 10140 8011069 YP_002970425.1 CDS frc NC_012815.1 1696307 1697638 D catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 1696307..1697638 Bifidobacterium animalis subsp. lactis DSM 10140 8011070 YP_002970426.1 CDS Balat_1450 NC_012815.1 1697843 1698979 R COG2730 Endoglucanase; secreted beta-mannosidase complement(1697843..1698979) Bifidobacterium animalis subsp. lactis DSM 10140 8011071 YP_002970427.1 CDS Balat_1451 NC_012815.1 1699704 1699835 D hypothetical protein 1699704..1699835 Bifidobacterium animalis subsp. lactis DSM 10140 8011072 YP_002970428.1 CDS Balat_1452 NC_012815.1 1699843 1700946 R COG0679 Predicted permeases; permease complement(1699843..1700946) Bifidobacterium animalis subsp. lactis DSM 10140 8011073 YP_002970429.1 CDS oxc NC_012815.1 1701051 1702832 R catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase complement(1701051..1702832) Bifidobacterium animalis subsp. lactis DSM 10140 8011074 YP_002970430.1 CDS Balat_1455 NC_012815.1 1703026 1704684 R COG0038 Chloride channel protein EriC; voltage gated chloride channel family protein complement(1703026..1704684) Bifidobacterium animalis subsp. lactis DSM 10140 8011075 YP_002970431.1 CDS capA NC_012815.1 1704882 1710140 R COG4932 Predicted outer membrane protein; collagen adhesion protein complement(1704882..1710140) Bifidobacterium animalis subsp. lactis DSM 10140 8011076 YP_002970432.1 CDS Balat_1457 NC_012815.1 1710232 1712307 R hypothetical protein complement(1710232..1712307) Bifidobacterium animalis subsp. lactis DSM 10140 8011077 YP_002970433.1 CDS Balat_1458 NC_012815.1 1712656 1714851 D COG0366 Glycosidases; Trehalose-6-phosphate hydrolase 1712656..1714851 Bifidobacterium animalis subsp. lactis DSM 10140 8011078 YP_002970434.1 CDS Balat_1459 NC_012815.1 1714971 1715480 D COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 1714971..1715480 Bifidobacterium animalis subsp. lactis DSM 10140 8011079 YP_002970435.1 CDS Balat_1460 NC_012815.1 1715579 1716427 R hypothetical protein complement(1715579..1716427) Bifidobacterium animalis subsp. lactis DSM 10140 8011080 YP_002970436.1 CDS Balat_1461 NC_012815.1 1716738 1717487 D COG0745 Response regulators consisting of aCheY-like receiver domain and a winged-helix DNA-binding domain; hypothetical protein 1716738..1717487 Bifidobacterium animalis subsp. lactis DSM 10140 8011081 YP_002970437.1 CDS Balat_1462 NC_012815.1 1717567 1718310 D COG0177 Predicted EndoIII-related endonuclease; putative EndoIII-related endonuclease 1717567..1718310 Bifidobacterium animalis subsp. lactis DSM 10140 8011082 YP_002970438.1 CDS Balat_1463 NC_012815.1 1718713 1718808 D hypothetical protein 1718713..1718808 Bifidobacterium animalis subsp. lactis DSM 10140 8011083 YP_002970439.1 CDS Balat_1464 NC_012815.1 1718890 1720425 D COG0747 ABC-type dipeptide transport system, periplasmic component; ABC transporter substrate-binding protein 1718890..1720425 Bifidobacterium animalis subsp. lactis DSM 10140 8011084 YP_002970440.1 CDS valS NC_012815.1 1720489 1723281 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1720489..1723281 Bifidobacterium animalis subsp. lactis DSM 10140 8011085 YP_002970441.1 CDS Balat_1466 NC_012815.1 1723499 1723978 D COG1522 Transcriptional regulators; AsnC family transcriptional regulator 1723499..1723978 Bifidobacterium animalis subsp. lactis DSM 10140 8011086 YP_002970442.1 CDS Balat_1467 NC_012815.1 1724049 1724438 D catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1724049..1724438 Bifidobacterium animalis subsp. lactis DSM 10140 8011087 YP_002970443.1 CDS Balat_1468 NC_012815.1 1724513 1726477 D hypothetical protein 1724513..1726477 Bifidobacterium animalis subsp. lactis DSM 10140 8011088 YP_002970444.1 CDS Balat_1469 NC_012815.1 1726566 1728569 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(1726566..1728569) Bifidobacterium animalis subsp. lactis DSM 10140 8011089 YP_002970445.1 CDS Balat_1470 NC_012815.1 1728792 1730408 R COG1232 Protoporphyrinogen oxidase; hypothetical protein complement(1728792..1730408) Bifidobacterium animalis subsp. lactis DSM 10140 8011090 YP_002970446.1 CDS Balat_1471 NC_012815.1 1730587 1730901 R hypothetical protein complement(1730587..1730901) Bifidobacterium animalis subsp. lactis DSM 10140 8011091 YP_002970447.1 CDS Balat_1472 NC_012815.1 1730910 1731953 R COG1670 Acetyltransferases, including N-acetylasesof ribosomal proteins; acetyltransferase complement(1730910..1731953) Bifidobacterium animalis subsp. lactis DSM 10140 8011092 YP_002970448.1 CDS gatB NC_012815.1 1732378 1733877 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1732378..1733877) Bifidobacterium animalis subsp. lactis DSM 10140 8011093 YP_002970449.1 CDS gatA NC_012815.1 1733898 1735442 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1733898..1735442) Bifidobacterium animalis subsp. lactis DSM 10140 8011094 YP_002970450.1 CDS gatC NC_012815.1 1735444 1735707 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(1735444..1735707) Bifidobacterium animalis subsp. lactis DSM 10140 8011095 YP_002970451.1 CDS Balat_1476 NC_012815.1 1735862 1736659 R hypothetical protein complement(1735862..1736659) Bifidobacterium animalis subsp. lactis DSM 10140 8011096 YP_002970452.1 CDS Balat_1477 NC_012815.1 1736806 1737591 R COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein complement(1736806..1737591) Bifidobacterium animalis subsp. lactis DSM 10140 8011097 YP_002970453.1 CDS Balat_1478 NC_012815.1 1737826 1738635 R COG0566 rRNA methylases; hypothetical protein complement(1737826..1738635) Bifidobacterium animalis subsp. lactis DSM 10140 8011098 YP_002970454.1 CDS Balat_1479 NC_012815.1 1738681 1739343 R COG0461 Orotate phosphoribosyltransferase; hypothetical protein complement(1738681..1739343) Bifidobacterium animalis subsp. lactis DSM 10140 8011099 YP_002970455.1 CDS Balat_1480 NC_012815.1 1739476 1740882 D COG2217 Cation transport ATPase; copper-transporting ATPase 1739476..1740882 Bifidobacterium animalis subsp. lactis DSM 10140 8011100 YP_002970456.1 CDS clpB NC_012815.1 1740976 1743663 R COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-binding subunit of Clp protease complement(1740976..1743663) Bifidobacterium animalis subsp. lactis DSM 10140 8011101 YP_002970457.1 CDS Balat_1482 NC_012815.1 1743910 1744731 R COG0179 2-keto-4-pentenoatehydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase complement(1743910..1744731) Bifidobacterium animalis subsp. lactis DSM 10140 8011102 YP_002970458.1 CDS Balat_1483 NC_012815.1 1744742 1745260 R hypothetical protein complement(1744742..1745260) Bifidobacterium animalis subsp. lactis DSM 10140 8011103 YP_002970459.1 CDS capB NC_012815.1 1745452 1747134 R cell surface protein fimA fimbrial subunit complement(1745452..1747134) Bifidobacterium animalis subsp. lactis DSM 10140 8011104 YP_002970460.1 CDS srtA NC_012815.1 1747329 1749344 R hypothetical protein complement(1747329..1749344) Bifidobacterium animalis subsp. lactis DSM 10140 8011105 YP_002970461.1 CDS Balat_1486 NC_012815.1 1750246 1751274 R COG3764 Sortase (surface protein transpeptidase); Sortase complement(1750246..1751274) Bifidobacterium animalis subsp. lactis DSM 10140 8011106 YP_002970462.1 CDS Balat_1487 NC_012815.1 1751317 1752162 R COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein complement(1751317..1752162) Bifidobacterium animalis subsp. lactis DSM 10140 8011107 YP_002970463.1 CDS Balat_1488 NC_012815.1 1752277 1753293 R COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-Q tRNA complement(1752277..1753293) Bifidobacterium animalis subsp. lactis DSM 10140 8011108 YP_002970464.1 CDS Balat_1489 NC_012815.1 1753293 1754204 R membrane protein complement(1753293..1754204) Bifidobacterium animalis subsp. lactis DSM 10140 8011109 YP_002970465.1 CDS Balat_1490 NC_012815.1 1754360 1755094 R COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator protein complement(1754360..1755094) Bifidobacterium animalis subsp. lactis DSM 10140 8011110 YP_002970466.1 CDS Balat_1491 NC_012815.1 1755250 1755609 R hypothetical protein complement(1755250..1755609) Bifidobacterium animalis subsp. lactis DSM 10140 8011111 YP_002970467.1 CDS Balat_1492 NC_012815.1 1755853 1755960 R hypothetical protein complement(1755853..1755960) Bifidobacterium animalis subsp. lactis DSM 10140 8011112 YP_002970468.1 CDS Balat_1494 NC_012815.1 1756403 1756966 R hypothetical protein complement(1756403..1756966) Bifidobacterium animalis subsp. lactis DSM 10140 8011114 YP_002970469.1 CDS Balat_1495 NC_012815.1 1757010 1757219 D hypothetical protein 1757010..1757219 Bifidobacterium animalis subsp. lactis DSM 10140 8011115 YP_002970470.1 CDS rplI NC_012815.1 1757525 1757971 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1757525..1757971) Bifidobacterium animalis subsp. lactis DSM 10140 8011116 YP_002970471.1 CDS rpsR NC_012815.1 1757992 1758240 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1757992..1758240) Bifidobacterium animalis subsp. lactis DSM 10140 8011117 YP_002970472.1 CDS Balat_1498 NC_012815.1 1758288 1758920 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1758288..1758920) Bifidobacterium animalis subsp. lactis DSM 10140 8011118 YP_002970473.1 CDS rpsF NC_012815.1 1758958 1759245 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1758958..1759245) Bifidobacterium animalis subsp. lactis DSM 10140 8011119 YP_002970474.1 CDS Balat_1500 NC_012815.1 1759482 1760453 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1759482..1760453 Bifidobacterium animalis subsp. lactis DSM 10140 8011120 YP_002970475.1 CDS Balat_1501 NC_012815.1 1760774 1761742 R COG0524 Sugar kinases, ribokinase family; PfkB family sugar kinase complement(1760774..1761742) Bifidobacterium animalis subsp. lactis DSM 10140 8011121 YP_002970476.1 CDS Balat_1502 NC_012815.1 1761845 1763323 R COG0477 Permeases of the major facilitator superfamily; tetracycline repressor protein complement(1761845..1763323) Bifidobacterium animalis subsp. lactis DSM 10140 8011122 YP_002970477.1 CDS Balat_1503 NC_012815.1 1763406 1764359 R COG1957 Inosine-uridine nucleoside N-ribohydrolase; putative nucleoside hydrolase protein complement(1763406..1764359) Bifidobacterium animalis subsp. lactis DSM 10140 8011123 YP_002970478.1 CDS Balat_1504 NC_012815.1 1764542 1765519 R COG1609 Transcriptional regulators; ribose operon repressor RbsR complement(1764542..1765519) Bifidobacterium animalis subsp. lactis DSM 10140 8011124 YP_002970479.1 CDS Balat_1508 NC_012815.1 1771847 1773031 R COG0562 UDP-galactopyranose mutase; UDP-galactopyranose mutase complement(1771847..1773031) Bifidobacterium animalis subsp. lactis DSM 10140 8011128 YP_002970480.1 CDS Balat_1509 NC_012815.1 1773252 1774337 D COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 1773252..1774337 Bifidobacterium animalis subsp. lactis DSM 10140 8011129 YP_002970481.1 CDS Balat_1510 NC_012815.1 1774477 1774575 D hypothetical protein 1774477..1774575 Bifidobacterium animalis subsp. lactis DSM 10140 8011130 YP_002970482.1 CDS Balat_1511 NC_012815.1 1774582 1775550 R COG1216 Predicted glycosyltransferases; putative glycosyl transferase complement(1774582..1775550) Bifidobacterium animalis subsp. lactis DSM 10140 8011131 YP_002970483.1 CDS Balat_1512 NC_012815.1 1775756 1777897 D COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Phosphoglycerol transferase 1775756..1777897 Bifidobacterium animalis subsp. lactis DSM 10140 8011132 YP_002970484.1 CDS Balat_1513 NC_012815.1 1777962 1778069 D hypothetical protein 1777962..1778069 Bifidobacterium animalis subsp. lactis DSM 10140 8011133 YP_002970485.1 CDS Balat_1514 NC_012815.1 1778083 1780407 D COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Phosphoglycerol transferase 1778083..1780407 Bifidobacterium animalis subsp. lactis DSM 10140 8011134 YP_002970486.1 CDS Balat_1515 NC_012815.1 1780419 1782473 D COG1216 Predicted glycosyltransferases; hypothetical protein 1780419..1782473 Bifidobacterium animalis subsp. lactis DSM 10140 8011135 YP_002970487.1 CDS Balat_1516 NC_012815.1 1782561 1783340 R COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); 1,4-beta-N-acetylmuramidase complement(1782561..1783340) Bifidobacterium animalis subsp. lactis DSM 10140 8011136 YP_002970488.1 CDS Balat_1517 NC_012815.1 1783523 1785130 R COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); 1,4-beta-N-acetylmuramidase complement(1783523..1785130) Bifidobacterium animalis subsp. lactis DSM 10140 8011137 YP_002970489.1 CDS Balat_1518 NC_012815.1 1785644 1786561 D COG3328 Transposase and inactivated derivatives; transposase 1785644..1786561 Bifidobacterium animalis subsp. lactis DSM 10140 8011138 YP_002970490.1 CDS Balat_1519 NC_012815.1 1786691 1787248 D COG4886 Leucine-rich repeat (LRR protein); N-acetylmuramoyl-L-alanine amidase 1786691..1787248 Bifidobacterium animalis subsp. lactis DSM 10140 8011139 YP_002970491.1 CDS Balat_1520 NC_012815.1 1787309 1787836 D Allergen V5/Tpx-1 family protein 1787309..1787836 Bifidobacterium animalis subsp. lactis DSM 10140 8011140 YP_002970492.1 CDS Balat_1521 NC_012815.1 1787988 1788689 R hypothetical protein complement(1787988..1788689) Bifidobacterium animalis subsp. lactis DSM 10140 8011141 YP_002970493.1 CDS Balat_1522 NC_012815.1 1788709 1790037 R hypothetical protein complement(1788709..1790037) Bifidobacterium animalis subsp. lactis DSM 10140 8011142 YP_002970494.1 CDS Balat_1523 NC_012815.1 1790061 1791476 R COG1134 ABC-type polysaccharide/polyol phosphatetransport system, ATPase component; ATP-driven polysaccharide export protein complement(1790061..1791476) Bifidobacterium animalis subsp. lactis DSM 10140 8011143 YP_002970495.1 CDS Balat_1524 NC_012815.1 1791476 1792267 R COG1682 ABC-type polysaccharide/polyol phosphateexport systems, permease component; polysaccharide ABC transporter permease complement(1791476..1792267) Bifidobacterium animalis subsp. lactis DSM 10140 8011144 YP_002970496.1 CDS Balat_1525 NC_012815.1 1792493 1794439 D COG1216 Predicted glycosyltransferases; hypothetical protein 1792493..1794439 Bifidobacterium animalis subsp. lactis DSM 10140 8011145 YP_002970497.1 CDS Balat_1527 NC_012815.1 1794730 1796913 R hypothetical protein complement(1794730..1796913) Bifidobacterium animalis subsp. lactis DSM 10140 8011147 YP_002970498.1 CDS Balat_1528 NC_012815.1 1796976 1799225 R putative PMT family glycosyltransferase complement(1796976..1799225) Bifidobacterium animalis subsp. lactis DSM 10140 8011148 YP_002970499.1 CDS Balat_1529 NC_012815.1 1799368 1799466 D hypothetical protein 1799368..1799466 Bifidobacterium animalis subsp. lactis DSM 10140 8011149 YP_002970500.1 CDS Balat_1530 NC_012815.1 1799516 1801147 R putative riboflavin-specific deaminase complement(1799516..1801147) Bifidobacterium animalis subsp. lactis DSM 10140 8011150 YP_002970501.1 CDS Balat_1531 NC_012815.1 1801491 1802831 D COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 1801491..1802831 Bifidobacterium animalis subsp. lactis DSM 10140 8011151 YP_002970502.1 CDS Balat_1532 NC_012815.1 1802833 1803897 D COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 1802833..1803897 Bifidobacterium animalis subsp. lactis DSM 10140 8011152 YP_002970503.1 CDS Balat_1533 NC_012815.1 1804090 1804878 R COG1418 Predicted HD superfamily hydrolase; hypothetical protein complement(1804090..1804878) Bifidobacterium animalis subsp. lactis DSM 10140 8011153 YP_002970504.1 CDS Balat_1534 NC_012815.1 1805117 1806019 R COG0121 Predicted glutamine amidotransferase; hypothetical protein complement(1805117..1806019) Bifidobacterium animalis subsp. lactis DSM 10140 8011154 YP_002970505.1 CDS Balat_1535 NC_012815.1 1806300 1808492 R COG3158 K+ transporter; potassium transport system protein kup 2 complement(1806300..1808492) Bifidobacterium animalis subsp. lactis DSM 10140 8011155 YP_002970506.1 CDS Balat_1536 NC_012815.1 1808698 1809654 R COG0084 Mg-dependent DNase; hypothetical protein complement(1808698..1809654) Bifidobacterium animalis subsp. lactis DSM 10140 8011156 YP_002970507.1 CDS Balat_1537 NC_012815.1 1809825 1812221 R COG3345 Alpha-galactosidase; alpha-galactosidase complement(1809825..1812221) Bifidobacterium animalis subsp. lactis DSM 10140 8011157 YP_002970508.1 CDS Balat_1538 NC_012815.1 1812299 1813012 R hypothetical protein complement(1812299..1813012) Bifidobacterium animalis subsp. lactis DSM 10140 8011158 YP_002970509.1 CDS Balat_1539 NC_012815.1 1813210 1815003 R COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1813210..1815003) Bifidobacterium animalis subsp. lactis DSM 10140 8011159 YP_002970510.1 CDS Balat_1540 NC_012815.1 1815112 1816908 R COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease complement(1815112..1816908) Bifidobacterium animalis subsp. lactis DSM 10140 8011160 YP_002970511.1 CDS Balat_1541 NC_012815.1 1816923 1817027 R hypothetical protein complement(1816923..1817027) Bifidobacterium animalis subsp. lactis DSM 10140 8011161 YP_002970512.1 CDS Balat_1542 NC_012815.1 1817878 1819737 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1817878..1819737) Bifidobacterium animalis subsp. lactis DSM 10140 8011162 YP_002970513.1 CDS Balat_1543 NC_012815.1 1820007 1820690 D hypothetical protein 1820007..1820690 Bifidobacterium animalis subsp. lactis DSM 10140 8011163 YP_002970514.1 CDS Balat_1544 NC_012815.1 1820725 1821171 D hypothetical protein 1820725..1821171 Bifidobacterium animalis subsp. lactis DSM 10140 8011164 YP_002970515.1 CDS Balat_1545 NC_012815.1 1821206 1822153 R COG0313 Predicted methyltransferases; hypothetical protein complement(1821206..1822153) Bifidobacterium animalis subsp. lactis DSM 10140 8011165 YP_002970516.1 CDS Balat_1546 NC_012815.1 1822311 1823924 D COG1928 Dolichyl-phosphate-mannose--proteinO-mannosyl transferase; glycosyl transferase family protein 1822311..1823924 Bifidobacterium animalis subsp. lactis DSM 10140 8011166 YP_002970517.1 CDS Balat_1547 NC_012815.1 1824475 1825296 D COG0657 Esterase/lipase; xylan esterase 1824475..1825296 Bifidobacterium animalis subsp. lactis DSM 10140 8011167 YP_002970518.1 CDS Balat_1548 NC_012815.1 1825617 1826366 D COG0586 Uncharacterized membrane-associated protein; hypothetical protein 1825617..1826366 Bifidobacterium animalis subsp. lactis DSM 10140 8011168 YP_002970519.1 CDS Balat_1550 NC_012815.1 1826682 1827425 R COG4832 Uncharacterized conserved protein; hypothetical protein complement(1826682..1827425) Bifidobacterium animalis subsp. lactis DSM 10140 8011170 YP_002970520.1 CDS Balat_1551 NC_012815.1 1827426 1829756 R COG1472 Beta-glucosidase-related glycosidases; beta-D-glucosideglucohydrolase complement(1827426..1829756) Bifidobacterium animalis subsp. lactis DSM 10140 8011171 YP_002970521.1 CDS Balat_1552 NC_012815.1 1829879 1830517 R COG1309 Transcriptional regulator; TetR family transcriptional regulator complement(1829879..1830517) Bifidobacterium animalis subsp. lactis DSM 10140 8011172 YP_002970522.1 CDS Balat_1553 NC_012815.1 1830773 1831459 R COG0637 Predicted phosphatase/phosphohexomutase; hypothetical protein complement(1830773..1831459) Bifidobacterium animalis subsp. lactis DSM 10140 8011173 YP_002970523.1 CDS Balat_1554 NC_012815.1 1831564 1832079 R COG0789 Predicted transcriptional regulators; MerR-type-transcriptional regulator HsrP complement(1831564..1832079) Bifidobacterium animalis subsp. lactis DSM 10140 8011174 YP_002970524.1 CDS dnaJ NC_012815.1 1832124 1833179 R COG2214 DnaJ-class molecular chaperone; molecular chaperone DnaJ complement(1832124..1833179) Bifidobacterium animalis subsp. lactis DSM 10140 8011175 YP_002970525.1 CDS grpE NC_012815.1 1833310 1833999 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1833310..1833999) Bifidobacterium animalis subsp. lactis DSM 10140 8011176 YP_002970526.1 CDS dnaK NC_012815.1 1833999 1835864 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1833999..1835864) Bifidobacterium animalis subsp. lactis DSM 10140 8011177 YP_002970527.1 CDS Balat_1558 NC_012815.1 1836001 1836156 R hypothetical protein complement(1836001..1836156) Bifidobacterium animalis subsp. lactis DSM 10140 8011178 YP_002970528.1 CDS Balat_1559 NC_012815.1 1836617 1837642 R COG1609 Transcriptional regulators; LacI-type transcriptional regulator complement(1836617..1837642) Bifidobacterium animalis subsp. lactis DSM 10140 8011179 YP_002970529.1 CDS Balat_1560 NC_012815.1 1837682 1838455 R putative ABC transporter membrane protein complement(1837682..1838455) Bifidobacterium animalis subsp. lactis DSM 10140 8011180 YP_002970530.1 CDS Balat_1561 NC_012815.1 1838471 1839274 R COG1011 Predicted hydrolase (HAD superfamily); halo acid dehalogenase-like hydrolase complement(1838471..1839274) Bifidobacterium animalis subsp. lactis DSM 10140 8011181 YP_002970531.1 CDS Balat_1562 NC_012815.1 1839264 1841363 R COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; pullulanase complement(1839264..1841363) Bifidobacterium animalis subsp. lactis DSM 10140 8011182 YP_002970532.1 CDS Balat_1563 NC_012815.1 1841368 1842336 R COG0395 ABC-type sugar transport system, permease component; putative sugar ABC transporter membrane protein complement(1841368..1842336) Bifidobacterium animalis subsp. lactis DSM 10140 8011183 YP_002970533.1 CDS Balat_1564 NC_012815.1 1842333 1843706 R COG1175 ABC-type sugar transport systems, permease components; putative sugar ABC transporter membrane protein complement(1842333..1843706) Bifidobacterium animalis subsp. lactis DSM 10140 8011184 YP_002970534.1 CDS Balat_1565 NC_012815.1 1844026 1845285 R COG2182 Maltose-binding periplasmic proteins/domains; putative sugar-binding secreted protein complement(1844026..1845285) Bifidobacterium animalis subsp. lactis DSM 10140 8011185 YP_002970535.1 CDS Balat_1566 NC_012815.1 1845555 1847159 D COG0366 Glycosidases; glycosylase 1845555..1847159 Bifidobacterium animalis subsp. lactis DSM 10140 8011186 YP_002970536.1 CDS Balat_1567 NC_012815.1 1847605 1849803 D COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 1847605..1849803 Bifidobacterium animalis subsp. lactis DSM 10140 8011187 YP_002970537.1 CDS Balat_1568 NC_012815.1 1850275 1850877 R hypothetical protein complement(1850275..1850877) Bifidobacterium animalis subsp. lactis DSM 10140 8011188 YP_002970538.1 CDS Balat_1569 NC_012815.1 1851196 1852032 R COG0395 ABC-type sugar transport system, permease component; MalG-type ABC sugar transport system permease complement(1851196..1852032) Bifidobacterium animalis subsp. lactis DSM 10140 8011189 YP_002970539.1 CDS Balat_1570 NC_012815.1 1852032 1852886 R COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease complement(1852032..1852886) Bifidobacterium animalis subsp. lactis DSM 10140 8011190 YP_002970540.1 CDS Balat_1571 NC_012815.1 1853349 1854359 D COG1609 Transcriptional regulators; LacI-type response repressor 1853349..1854359 Bifidobacterium animalis subsp. lactis DSM 10140 8011191 YP_002970541.1 CDS Balat_1572 NC_012815.1 1854711 1856045 R COG1653 ABC-type sugar transport system, periplasmic component; ABC transporter substrate-binding protein complement(1854711..1856045) Bifidobacterium animalis subsp. lactis DSM 10140 8011192 YP_002970542.1 CDS Balat_1573 NC_012815.1 1856404 1858179 D COG0366 Glycosidases; alpha-1,4-glucosidase 1856404..1858179 Bifidobacterium animalis subsp. lactis DSM 10140 8011193 YP_002970543.1 CDS Balat_1574 NC_012815.1 1858509 1859177 R COG0406 Fructose-2,6-bisphosphatase; Broad specificity phosphatase complement(1858509..1859177) Bifidobacterium animalis subsp. lactis DSM 10140 8011194 YP_002970544.1 CDS Balat_1575 NC_012815.1 1859340 1859756 D hypothetical protein 1859340..1859756 Bifidobacterium animalis subsp. lactis DSM 10140 8011195 YP_002970545.1 CDS Balat_1576 NC_012815.1 1859856 1860632 D COG0778 Nitroreductase; NADPH-flavin oxidoreductase 1859856..1860632 Bifidobacterium animalis subsp. lactis DSM 10140 8011196 YP_002970546.1 CDS Balat_1577 NC_012815.1 1860958 1861209 R hypothetical protein complement(1860958..1861209) Bifidobacterium animalis subsp. lactis DSM 10140 8011197 YP_002970547.1 CDS Balat_1578 NC_012815.1 1861255 1861845 R COG0477 Permeases of the major facilitator superfamily; hypothetical protein complement(1861255..1861845) Bifidobacterium animalis subsp. lactis DSM 10140 8011198 YP_002970548.1 CDS Balat_1582 NC_012815.1 1868120 1868656 D COG0388 Predicted amidohydrolase; NAD synthetase 1868120..1868656 Bifidobacterium animalis subsp. lactis DSM 10140 8011202 YP_002970549.1 CDS Balat_1583 NC_012815.1 1868691 1870025 D COG0388 Predicted amidohydrolase; NAD+ synthetase 1868691..1870025 Bifidobacterium animalis subsp. lactis DSM 10140 8011203 YP_002970550.1 CDS Balat_1584 NC_012815.1 1870189 1870458 R COG3077 DNA-damage-inducible protein J; hypothetical protein complement(1870189..1870458) Bifidobacterium animalis subsp. lactis DSM 10140 8011204 YP_002970551.1 CDS Balat_1588 NC_012815.1 1876816 1878261 R COG2211 Na+/melibiose symporter and related transporters; Na+/xyloside symporter related transporter complement(1876816..1878261) Bifidobacterium animalis subsp. lactis DSM 10140 8011208 YP_002970552.1 CDS Balat_1589 NC_012815.1 1878450 1880465 R COG3533 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1878450..1880465) Bifidobacterium animalis subsp. lactis DSM 10140 8011209 YP_002970553.1 CDS Balat_1590 NC_012815.1 1880600 1881649 D COG1609 Transcriptional regulators; LacI-type transcriptional regulator 1880600..1881649 Bifidobacterium animalis subsp. lactis DSM 10140 8011210 YP_002970554.1 CDS Balat_1591 NC_012815.1 1881720 1882475 D COG0846 NAD-dependent protein deacetylases, SIR2family; NAD-dependent protein deacetylase 1881720..1882475 Bifidobacterium animalis subsp. lactis DSM 10140 8011211 YP_002970555.1 CDS Balat_1592 NC_012815.1 1882633 1883871 R catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase complement(1882633..1883871) Bifidobacterium animalis subsp. lactis DSM 10140 8011212 YP_002970556.1 CDS Balat_1593 NC_012815.1 1884058 1885893 R COG0366 Glycosidases; oligo-1,6-glucosidase complement(1884058..1885893) Bifidobacterium animalis subsp. lactis DSM 10140 8011213 YP_002970557.1 CDS Balat_1594 NC_012815.1 1885972 1886100 R hypothetical protein complement(1885972..1886100) Bifidobacterium animalis subsp. lactis DSM 10140 8011214 YP_002970558.1 CDS Balat_1595 NC_012815.1 1886694 1887650 D hypothetical protein 1886694..1887650 Bifidobacterium animalis subsp. lactis DSM 10140 8011215 YP_002970559.1 CDS Balat_1596 NC_012815.1 1888091 1889701 R COG3345 Alpha-galactosidase; alpha-galactosidase complement(1888091..1889701) Bifidobacterium animalis subsp. lactis DSM 10140 8011216 YP_002970560.1 CDS Balat_1597 NC_012815.1 1890936 1891841 R COG0395 ABC-type sugar transport system, permease component; MalG-type ABC sugar transport system permease complement(1890936..1891841) Bifidobacterium animalis subsp. lactis DSM 10140 8011217 YP_002970561.1 CDS Balat_1598 NC_012815.1 1891846 1892838 R COG1175 ABC-type sugar transport systems, permease components; MalF-type ABC sugar transport systems permease complement(1891846..1892838) Bifidobacterium animalis subsp. lactis DSM 10140 8011218 YP_002970562.1 CDS Balat_1599 NC_012815.1 1892872 1894185 R COG1653 ABC-type sugar transport system, periplasmic component; sugar binding protein of ABC transporter system complement(1892872..1894185) Bifidobacterium animalis subsp. lactis DSM 10140 8011219 YP_002970563.1 CDS Balat_1600 NC_012815.1 1894316 1895524 D COG1940 Transcriptional regulator/sugar kinase; NagC-type transcriptional regulator 1894316..1895524 Bifidobacterium animalis subsp. lactis DSM 10140 8011220 YP_002970564.1 CDS Balat_1601 NC_012815.1 1895549 1897771 R COG3345 Alpha-galactosidase; alpha-galactosidase complement(1895549..1897771) Bifidobacterium animalis subsp. lactis DSM 10140 8011221 YP_002970565.1 CDS Balat_1602 NC_012815.1 1897887 1898396 R COG0590 Cytosine/adenosine deaminases; Cytosine/adenosine deaminase complement(1897887..1898396) Bifidobacterium animalis subsp. lactis DSM 10140 8011222 YP_002970566.1 CDS Balat_1603 NC_012815.1 1898546 1900618 D COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; NhaP-type Na(+)/H(+) exchanger 1898546..1900618 Bifidobacterium animalis subsp. lactis DSM 10140 8011223 YP_002970567.1 CDS Balat_1604 NC_012815.1 1900689 1901627 R COG0400 Predicted esterase; phospholipase/carboxylesterase complement(1900689..1901627) Bifidobacterium animalis subsp. lactis DSM 10140 8011224 YP_002970568.1 CDS Balat_1605 NC_012815.1 1901670 1903229 R hypothetical protein complement(1901670..1903229) Bifidobacterium animalis subsp. lactis DSM 10140 8011225 YP_002970569.1 CDS dcd NC_012815.1 1903279 1903860 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(1903279..1903860) Bifidobacterium animalis subsp. lactis DSM 10140 8011226 YP_002970570.1 CDS Balat_1607 NC_012815.1 1904070 1907060 R COG0474 Cation transport ATPase; cation-transporting ATPase PacL complement(1904070..1907060) Bifidobacterium animalis subsp. lactis DSM 10140 8011227 YP_002970571.1 CDS Balat_1608 NC_012815.1 1907375 1908370 D COG0566 rRNA methylases; tRNA/rRNA methyltransferase protein 1907375..1908370 Bifidobacterium animalis subsp. lactis DSM 10140 8011228 YP_002970572.1 CDS Balat_1609 NC_012815.1 1908519 1909967 R COG0515 Serine/threonine protein kinase; hypothetical protein complement(1908519..1909967) Bifidobacterium animalis subsp. lactis DSM 10140 8011229 YP_002970573.1 CDS Balat_1610 NC_012815.1 1910175 1911308 R COG3839 ABC-type sugar transport systems, ATPase components; sugar ABC transporter ATP binding protein complement(1910175..1911308) Bifidobacterium animalis subsp. lactis DSM 10140 8011230 YP_002970574.1 CDS Balat_1611 NC_012815.1 1911732 1912754 D COG1226 Kef-type K+ transport systems, predictedNAD-binding component; Kef-type K+ transport systems NAD-binding protein 1911732..1912754 Bifidobacterium animalis subsp. lactis DSM 10140 8011231 YP_002970575.1 CDS Balat_1612 NC_012815.1 1912824 1914941 D COG0515 Serine/threonine protein kinase; hypothetical protein 1912824..1914941 Bifidobacterium animalis subsp. lactis DSM 10140 8011232 YP_002970576.1 CDS Balat_1613 NC_012815.1 1915321 1916358 D COG1651 Protein-disulfide isomerase; hypothetical protein 1915321..1916358 Bifidobacterium animalis subsp. lactis DSM 10140 8011233 YP_002970577.1 CDS Balat_1615 NC_012815.1 1917026 1918573 D COG3583 Uncharacterized protein conserved in bacteria; hypothetical protein 1917026..1918573 Bifidobacterium animalis subsp. lactis DSM 10140 8011235 YP_002970578.1 CDS ksgA NC_012815.1 1918715 1919608 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1918715..1919608 Bifidobacterium animalis subsp. lactis DSM 10140 8011236 YP_002970579.1 CDS Balat_1617 NC_012815.1 1919605 1920561 D COG0030 Dimethyladenosine transferase (rRNAmethylation); dimethyladenosine transferase 1919605..1920561 Bifidobacterium animalis subsp. lactis DSM 10140 8011237 YP_002970580.1 CDS Balat_1618 NC_012815.1 1920633 1921259 D hypothetical protein 1920633..1921259 Bifidobacterium animalis subsp. lactis DSM 10140 8011238 YP_002970581.1 CDS Balat_1619 NC_012815.1 1921389 1922897 R COG0617 tRNA nucleotidyltransferase/poly(Apolymerase); RNA nucleotidyltransferase complement(1921389..1922897) Bifidobacterium animalis subsp. lactis DSM 10140 8011239 YP_002970582.1 CDS Balat_1620 NC_012815.1 1922993 1923997 D COG0494 NTP pyrophosphohydrolases includingoxidative damage repair enzymes; hypothetical protein 1922993..1923997 Bifidobacterium animalis subsp. lactis DSM 10140 8011240 YP_002970583.1 CDS Balat_1621 NC_012815.1 1924000 1926249 D hypothetical protein 1924000..1926249 Bifidobacterium animalis subsp. lactis DSM 10140 8011241 YP_002970584.1 CDS Balat_1622 NC_012815.1 1926246 1930268 D COG0728 Uncharacterized membrane protein, putativevirulence factor; hypothetical protein 1926246..1930268 Bifidobacterium animalis subsp. lactis DSM 10140 8011242 YP_002970585.1 CDS Balat_1623 NC_012815.1 1930509 1931471 D COG0492 Thioredoxin reductase; thioredoxin reductase 1930509..1931471 Bifidobacterium animalis subsp. lactis DSM 10140 8011243 YP_002970586.1 CDS Balat_1624 NC_012815.1 1931581 1932969 R COG1475 Predicted transcriptional regulators; chromosome partitioning protein complement(1931581..1932969) Bifidobacterium animalis subsp. lactis DSM 10140 8011244 YP_002970587.1 CDS Balat_1625 NC_012815.1 1932969 1933943 R COG1192 ATPases involved in chromosomepartitioning; ATPase for chromosome partitioning complement(1932969..1933943) Bifidobacterium animalis subsp. lactis DSM 10140 8011245 YP_002970588.1 CDS gidB NC_012815.1 1934577 1935320 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(1934577..1935320) Bifidobacterium animalis subsp. lactis DSM 10140 8011246 YP_002970589.1 CDS Balat_1627 NC_012815.1 1935776 1936318 R COG1847 Predicted RNA-binding protein; hypothetical protein complement(1935776..1936318) Bifidobacterium animalis subsp. lactis DSM 10140 8011247 YP_002970590.1 CDS Balat_1628 NC_012815.1 1936441 1937451 R COG0706 Preprotein translocase subunit YidC; Preprotein translocase subunit complement(1936441..1937451) Bifidobacterium animalis subsp. lactis DSM 10140 8011248 YP_002970591.1 CDS Balat_1629 NC_012815.1 1937452 1937745 R COG0759 Uncharacterized conserved protein; hypothetical protein complement(1937452..1937745) Bifidobacterium animalis subsp. lactis DSM 10140 8011249 YP_002970592.1 CDS Balat_1630 NC_012815.1 1937766 1938122 R COG0594 RNase P protein component; ribonuclease P protein component complement(1937766..1938122) Bifidobacterium animalis subsp. lactis DSM 10140 8011250 YP_002970593.1 CDS rpmH NC_012815.1 1938135 1938269 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1938135..1938269) Bifidobacterium animalis subsp. lactis DSM 10140 8011251 Balat_0016 tRNA Balat_0016 NC_012815.1 19649 19721 R tRNA-Ala complement(19649..19721) Bifidobacterium animalis subsp. lactis DSM 10140 8009638 Balat_0017 tRNA Balat_0017 NC_012815.1 19753 19826 R tRNA-Ile complement(19753..19826) Bifidobacterium animalis subsp. lactis DSM 10140 8009639 Balat_0098 tRNA Balat_0098 NC_012815.1 111926 112011 R tRNA-Leu complement(111926..112011) Bifidobacterium animalis subsp. lactis DSM 10140 8009720 Balat_0105 tRNA Balat_0105 NC_012815.1 122476 122549 R tRNA-Gly complement(122476..122549) Bifidobacterium animalis subsp. lactis DSM 10140 8009727 Balat_0186 tRNA Balat_0186 NC_012815.1 217392 217464 R tRNA-Lys complement(217392..217464) Bifidobacterium animalis subsp. lactis DSM 10140 8009808 Balat_0237 tRNA Balat_0237 NC_012815.1 284731 284806 D tRNA-Glu 284731..284806 Bifidobacterium animalis subsp. lactis DSM 10140 8009859 Balat_0238 tRNA Balat_0238 NC_012815.1 284839 284913 D tRNA-Gln 284839..284913 Bifidobacterium animalis subsp. lactis DSM 10140 8009860 Balat_0290 tRNA Balat_0290 NC_012815.1 356964 357048 R tRNA-Leu complement(356964..357048) Bifidobacterium animalis subsp. lactis DSM 10140 8009912 Balat_0291 tRNA Balat_0291 NC_012815.1 357106 357181 R tRNA-Thr complement(357106..357181) Bifidobacterium animalis subsp. lactis DSM 10140 8009913 Balat_0307 tRNA Balat_0307 NC_012815.1 377823 377898 D tRNA-Trp 377823..377898 Bifidobacterium animalis subsp. lactis DSM 10140 8009929 Balat_0319 tRNA Balat_0319 NC_012815.1 397187 397260 D tRNA-Gly 397187..397260 Bifidobacterium animalis subsp. lactis DSM 10140 8009941 Balat_0360 tRNA Balat_0360 NC_012815.1 445871 445952 D tRNA-Tyr 445871..445952 Bifidobacterium animalis subsp. lactis DSM 10140 8009982 Balat_0361 tRNA Balat_0361 NC_012815.1 445954 446028 D tRNA-Thr 445954..446028 Bifidobacterium animalis subsp. lactis DSM 10140 8009983 Balat_0362 tRNA Balat_0362 NC_012815.1 446030 446106 D tRNA-Met 446030..446106 Bifidobacterium animalis subsp. lactis DSM 10140 8009984 Balat_0369 tRNA Balat_0369 NC_012815.1 452772 452862 D tRNA-Ser 452772..452862 Bifidobacterium animalis subsp. lactis DSM 10140 8009991 Balat_0411 tRNA Balat_0411 NC_012815.1 485206 485294 R tRNA-Ser complement(485206..485294) Bifidobacterium animalis subsp. lactis DSM 10140 8010033 Balat_0422 tRNA Balat_0422 NC_012815.1 498894 498981 R tRNA-Ser complement(498894..498981) Bifidobacterium animalis subsp. lactis DSM 10140 8010044 Balat_0436 tRNA Balat_0436 NC_012815.1 516190 516263 R tRNA-Pro complement(516190..516263) Bifidobacterium animalis subsp. lactis DSM 10140 8010058 Balat_0462 tRNA Balat_0462 NC_012815.1 549317 549391 D tRNA-Glu 549317..549391 Bifidobacterium animalis subsp. lactis DSM 10140 8010084 Balat_0488 tRNA Balat_0488 NC_012815.1 581503 581579 D tRNA-Asp 581503..581579 Bifidobacterium animalis subsp. lactis DSM 10140 8010110 Balat_0489 tRNA Balat_0489 NC_012815.1 581613 581689 D tRNA-Asp 581613..581689 Bifidobacterium animalis subsp. lactis DSM 10140 8010111 Balat_0490 tRNA Balat_0490 NC_012815.1 581714 581789 D tRNA-Phe 581714..581789 Bifidobacterium animalis subsp. lactis DSM 10140 8010112 Balat_0508 tRNA Balat_0508 NC_012815.1 602652 602725 D tRNA-Met 602652..602725 Bifidobacterium animalis subsp. lactis DSM 10140 8010130 Balat_0587 tRNA Balat_0587 NC_012815.1 693427 693500 D tRNA-Arg 693427..693500 Bifidobacterium animalis subsp. lactis DSM 10140 8010209 Balat_0615 tRNA Balat_0615 NC_012815.1 726022 726097 R tRNA-His complement(726022..726097) Bifidobacterium animalis subsp. lactis DSM 10140 8010237 Balat_0743 tRNA Balat_0743 NC_012815.1 877625 877698 D tRNA-Gln 877625..877698 Bifidobacterium animalis subsp. lactis DSM 10140 8010365 Balat_0749 tRNA Balat_0749 NC_012815.1 881423 881498 D tRNA-Ala 881423..881498 Bifidobacterium animalis subsp. lactis DSM 10140 8010370 Balat_0762 tRNA Balat_0762 NC_012815.1 894922 894997 D tRNA-Asn 894922..894997 Bifidobacterium animalis subsp. lactis DSM 10140 8010383 Balat_0764 tRNA Balat_0764 NC_012815.1 895730 895805 D tRNA-Asn 895730..895805 Bifidobacterium animalis subsp. lactis DSM 10140 8010385 Balat_0809 tRNA Balat_0809 NC_012815.1 937253 937326 R tRNA-Pro complement(937253..937326) Bifidobacterium animalis subsp. lactis DSM 10140 8010430 Balat_0829 tRNA Balat_0829 NC_012815.1 957384 957456 R tRNA-Gly complement(957384..957456) Bifidobacterium animalis subsp. lactis DSM 10140 8010450 Balat_0833 tRNA Balat_0833 NC_012815.1 959330 959405 R tRNA-Val complement(959330..959405) Bifidobacterium animalis subsp. lactis DSM 10140 8010454 Balat_0834 tRNA Balat_0834 NC_012815.1 959436 959510 R tRNA-Val complement(959436..959510) Bifidobacterium animalis subsp. lactis DSM 10140 8010455 Balat_0835 tRNA Balat_0835 NC_012815.1 959539 959612 R tRNA-Cys complement(959539..959612) Bifidobacterium animalis subsp. lactis DSM 10140 8010456 Balat_0836 tRNA Balat_0836 NC_012815.1 959640 959715 R tRNA-Gly complement(959640..959715) Bifidobacterium animalis subsp. lactis DSM 10140 8010457 Balat_0910 tRNA Balat_0910 NC_012815.1 1047273 1047363 D tRNA-Leu 1047273..1047363 Bifidobacterium animalis subsp. lactis DSM 10140 8010531 Balat_0975 tRNA Balat_0975 NC_012815.1 1114128 1114204 R tRNA-Pro complement(1114128..1114204) Bifidobacterium animalis subsp. lactis DSM 10140 8010596 Balat_0983 tRNA Balat_0983 NC_012815.1 1124032 1124108 R tRNA-Leu complement(1124032..1124108) Bifidobacterium animalis subsp. lactis DSM 10140 8010604 Balat_1013 tRNA Balat_1013 NC_012815.1 1158928 1159009 R tRNA-Leu complement(1158928..1159009) Bifidobacterium animalis subsp. lactis DSM 10140 8010634 Balat_1074 tRNA Balat_1074 NC_012815.1 1232002 1232078 R tRNA-Arg complement(1232002..1232078) Bifidobacterium animalis subsp. lactis DSM 10140 8010695 Balat_1075 tRNA Balat_1075 NC_012815.1 1232125 1232198 R tRNA-Arg complement(1232125..1232198) Bifidobacterium animalis subsp. lactis DSM 10140 8010696 Balat_1252 tRNA Balat_1252 NC_012815.1 1446840 1446913 D tRNA-Val 1446840..1446913 Bifidobacterium animalis subsp. lactis DSM 10140 8010873 Balat_1280 tRNA Balat_1280 NC_012815.1 1477532 1477606 D tRNA-Val 1477532..1477606 Bifidobacterium animalis subsp. lactis DSM 10140 8010901 Balat_1281 tRNA Balat_1281 NC_012815.1 1477631 1477703 D tRNA-Gly 1477631..1477703 Bifidobacterium animalis subsp. lactis DSM 10140 8010902 Balat_1319 tRNA Balat_1319 NC_012815.1 1528095 1528167 D tRNA-Arg 1528095..1528167 Bifidobacterium animalis subsp. lactis DSM 10140 8010940 Balat_1422 tRNA Balat_1422 NC_012815.1 1671141 1671216 R tRNA-Arg complement(1671141..1671216) Bifidobacterium animalis subsp. lactis DSM 10140 8011043 Balat_1439 tRNA Balat_1439 NC_012815.1 1688162 1688238 D tRNA-Met 1688162..1688238 Bifidobacterium animalis subsp. lactis DSM 10140 8011060 Balat_1493 tRNA Balat_1493 NC_012815.1 1756198 1756274 R tRNA-Lys complement(1756198..1756274) Bifidobacterium animalis subsp. lactis DSM 10140 8011113 Balat_1526 tRNA Balat_1526 NC_012815.1 1794542 1794626 D tRNA-Ser 1794542..1794626 Bifidobacterium animalis subsp. lactis DSM 10140 8011146 Balat_1549 tRNA Balat_1549 NC_012815.1 1826540 1826615 D tRNA-Ala 1826540..1826615 Bifidobacterium animalis subsp. lactis DSM 10140 8011169 Balat_1614 tRNA Balat_1614 NC_012815.1 1916572 1916648 D tRNA-Thr 1916572..1916648 Bifidobacterium animalis subsp. lactis DSM 10140 8011234 Balat_1277 rRNA Balat_1277 NC_012815.1 1471069 1471185 R 5S ribosomal RNA complement(1471069..1471185) Bifidobacterium animalis subsp. lactis DSM 10140 8010898 Balat_1278 rRNA Balat_1278 NC_012815.1 1471265 1474391 R 23S ribosomal RNA complement(1471265..1474391) Bifidobacterium animalis subsp. lactis DSM 10140 8010899 Balat_1279 rRNA Balat_1279 NC_012815.1 1474835 1476383 R 16S ribosomal RNA complement(1474835..1476383) Bifidobacterium animalis subsp. lactis DSM 10140 8010900 Balat_1505 rRNA Balat_1505 NC_012815.1 1765950 1766066 R 5S ribosomal RNA complement(1765950..1766066) Bifidobacterium animalis subsp. lactis DSM 10140 8011125 Balat_1506 rRNA Balat_1506 NC_012815.1 1766146 1769272 R 23S ribosomal RNA complement(1766146..1769272) Bifidobacterium animalis subsp. lactis DSM 10140 8011126 Balat_1507 rRNA Balat_1507 NC_012815.1 1769716 1771264 R 16S ribosomal RNA complement(1769716..1771264) Bifidobacterium animalis subsp. lactis DSM 10140 8011127 Balat_1579 rRNA Balat_1579 NC_012815.1 1862179 1862295 R 5S ribosomal RNA complement(1862179..1862295) Bifidobacterium animalis subsp. lactis DSM 10140 8011199 Balat_1580 rRNA Balat_1580 NC_012815.1 1862373 1865501 R 23S ribosomal RNA complement(1862373..1865501) Bifidobacterium animalis subsp. lactis DSM 10140 8011200 Balat_1581 rRNA Balat_1581 NC_012815.1 1865947 1867495 R 16S ribosomal RNA complement(1865947..1867495) Bifidobacterium animalis subsp. lactis DSM 10140 8011201 Balat_1585 rRNA Balat_1585 NC_012815.1 1870891 1871007 R 5S ribosomal RNA complement(1870891..1871007) Bifidobacterium animalis subsp. lactis DSM 10140 8011205 Balat_1586 rRNA Balat_1586 NC_012815.1 1871087 1874213 R 23S ribosomal RNA complement(1871087..1874213) Bifidobacterium animalis subsp. lactis DSM 10140 8011206 Balat_1587 rRNA Balat_1587 NC_012815.1 1874657 1876206 R 16S ribosomal RNA complement(1874657..1876206) Bifidobacterium animalis subsp. lactis DSM 10140 8011207