-- dump date   	20140619_003010
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1035817000001	MobA/MobL family; Region: MobA_MobL; pfam03389
1035817000002	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817000003	Integrase core domain; Region: rve; pfam00665
1035817000004	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1035817000005	type VII secretion protein EsaA, N-terminal domain; Region: T7_esaA_Nterm; TIGR03929
1035817000006	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1035817000007	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1035817000008	Predicted membrane protein [Function unknown]; Region: COG1511
1035817000009	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1035817000010	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1035817000011	Protein of unknown function (DUF4235); Region: DUF4235; pfam14019
1035817000012	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817000013	catalytic core [active]
1035817000014	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817000015	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817000016	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817000017	DNA binding site [nucleotide binding]
1035817000018	domain linker motif; other site
1035817000019	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817000020	ligand binding site [chemical binding]; other site
1035817000021	dimerization interface [polypeptide binding]; other site
1035817000022	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1035817000023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817000024	putative PBP binding loops; other site
1035817000025	dimer interface [polypeptide binding]; other site
1035817000026	ABC-ATPase subunit interface; other site
1035817000027	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817000028	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817000029	dimer interface [polypeptide binding]; other site
1035817000030	conserved gate region; other site
1035817000031	putative PBP binding loops; other site
1035817000032	ABC-ATPase subunit interface; other site
1035817000033	Protein of unknown function, DUF624; Region: DUF624; pfam04854
1035817000034	Protein of unknown function, DUF624; Region: DUF624; cl02369
1035817000035	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1035817000036	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
1035817000037	Glycosyl hydrolase family 43; Region: GH43_4; cd08983
1035817000038	active site
1035817000039	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1035817000040	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1035817000041	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1672
1035817000042	AAA domain; Region: AAA_14; pfam13173
1035817000043	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
1035817000044	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
1035817000045	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1035817000046	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817000047	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817000048	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1035817000049	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817000050	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817000051	Walker A/P-loop; other site
1035817000052	ATP binding site [chemical binding]; other site
1035817000053	Q-loop/lid; other site
1035817000054	ABC transporter signature motif; other site
1035817000055	Walker B; other site
1035817000056	D-loop; other site
1035817000057	H-loop/switch region; other site
1035817000058	Mechanosensitive ion channel porin domain; Region: MscS_porin; pfam12795
1035817000059	FtsX-like permease family; Region: FtsX; pfam02687
1035817000060	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817000061	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1035817000062	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1035817000063	Divergent AAA domain; Region: AAA_4; pfam04326
1035817000064	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1035817000065	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
1035817000066	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
1035817000067	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1035817000068	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1035817000069	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
1035817000070	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1035817000071	Glycosyl hydrolase family 43; Region: GH43_6; cd08985
1035817000072	active site
1035817000073	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1035817000074	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
1035817000075	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
1035817000076	BRO family, N-terminal domain; Region: Bro-N; pfam02498
1035817000077	potential frameshift: common BLAST hit: gi|296455061|ref|YP_003662205.1| MarR family transcriptional regulator
1035817000078	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817000079	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817000080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000081	Walker A/P-loop; other site
1035817000082	ATP binding site [chemical binding]; other site
1035817000083	Q-loop/lid; other site
1035817000084	ABC transporter signature motif; other site
1035817000085	Walker B; other site
1035817000086	D-loop; other site
1035817000087	H-loop/switch region; other site
1035817000088	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817000089	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817000090	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1035817000091	Walker A/P-loop; other site
1035817000092	ATP binding site [chemical binding]; other site
1035817000093	Q-loop/lid; other site
1035817000094	ABC transporter signature motif; other site
1035817000095	Walker B; other site
1035817000096	D-loop; other site
1035817000097	H-loop/switch region; other site
1035817000098	ApbE family; Region: ApbE; pfam02424
1035817000099	MFS/sugar transport protein; Region: MFS_2; pfam13347
1035817000100	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1035817000101	Predicted methyltransferases [General function prediction only]; Region: COG0313
1035817000102	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1035817000103	putative SAM binding site [chemical binding]; other site
1035817000104	putative homodimer interface [polypeptide binding]; other site
1035817000105	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817000106	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
1035817000107	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1035817000108	active site
1035817000109	HIGH motif; other site
1035817000110	KMSKS motif; other site
1035817000111	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1035817000112	tRNA binding surface [nucleotide binding]; other site
1035817000113	anticodon binding site; other site
1035817000114	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1035817000115	trimer interface [polypeptide binding]; other site
1035817000116	active site
1035817000117	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cl00298
1035817000118	active site
1035817000119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1035817000120	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1035817000121	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1035817000122	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1035817000123	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1035817000124	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817000125	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817000126	DNA binding site [nucleotide binding]
1035817000127	domain linker motif; other site
1035817000128	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817000129	dimerization interface [polypeptide binding]; other site
1035817000130	ligand binding site [chemical binding]; other site
1035817000131	alpha-galactosidase; Region: PLN02808; cl17638
1035817000132	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817000133	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817000134	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000135	Walker A/P-loop; other site
1035817000136	ATP binding site [chemical binding]; other site
1035817000137	Q-loop/lid; other site
1035817000138	ABC transporter signature motif; other site
1035817000139	Walker B; other site
1035817000140	D-loop; other site
1035817000141	H-loop/switch region; other site
1035817000142	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817000143	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817000144	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1035817000145	Walker A/P-loop; other site
1035817000146	ATP binding site [chemical binding]; other site
1035817000147	Q-loop/lid; other site
1035817000148	ABC transporter signature motif; other site
1035817000149	Walker B; other site
1035817000150	D-loop; other site
1035817000151	H-loop/switch region; other site
1035817000152	Fic family protein [Function unknown]; Region: COG3177
1035817000153	Fic/DOC family; Region: Fic; pfam02661
1035817000154	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1035817000155	active site
1035817000156	K+ potassium transporter; Region: K_trans; pfam02705
1035817000157	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1035817000158	putative active site [active]
1035817000159	putative dimer interface [polypeptide binding]; other site
1035817000160	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1035817000161	Zn2+ binding site [ion binding]; other site
1035817000162	Mg2+ binding site [ion binding]; other site
1035817000163	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000164	ABC transporter; Region: ABC_tran; pfam00005
1035817000165	Q-loop/lid; other site
1035817000166	ABC transporter signature motif; other site
1035817000167	Walker B; other site
1035817000168	D-loop; other site
1035817000169	H-loop/switch region; other site
1035817000170	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817000171	FtsX-like permease family; Region: FtsX; pfam02687
1035817000172	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
1035817000173	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1035817000174	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1035817000175	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
1035817000176	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1035817000177	Ligand binding site; other site
1035817000178	Putative Catalytic site; other site
1035817000179	DXD motif; other site
1035817000180	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1035817000181	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1035817000182	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1035817000183	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1035817000184	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_b; cd04185
1035817000185	Probable Catalytic site; other site
1035817000186	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1035817000187	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1035817000188	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1035817000189	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1035817000190	Walker A/P-loop; other site
1035817000191	ATP binding site [chemical binding]; other site
1035817000192	Q-loop/lid; other site
1035817000193	ABC transporter signature motif; other site
1035817000194	Walker B; other site
1035817000195	D-loop; other site
1035817000196	H-loop/switch region; other site
1035817000197	LicD family; Region: LicD; pfam04991
1035817000198	potential frameshift: common BLAST hit: gi|189440427|ref|YP_001955508.1| phosphoglycerol transferase
1035817000199	Sulfatase; Region: Sulfatase; cl17466
1035817000200	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1035817000201	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1035817000202	NAD binding site [chemical binding]; other site
1035817000203	substrate binding site [chemical binding]; other site
1035817000204	homodimer interface [polypeptide binding]; other site
1035817000205	active site
1035817000206	Helix-turn-helix domain; Region: HTH_17; cl17695
1035817000207	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1035817000208	putative active site [active]
1035817000209	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1035817000210	dimer interface [polypeptide binding]; other site
1035817000211	ADP-ribose binding site [chemical binding]; other site
1035817000212	active site
1035817000213	nudix motif; other site
1035817000214	metal binding site [ion binding]; metal-binding site
1035817000215	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1035817000216	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1035817000217	UDP-galactopyranose mutase; Region: GLF; pfam03275
1035817000218	Domain of unknown function (DUF2437); Region: DUF2437; pfam10370
1035817000219	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1035817000220	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1035817000221	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1035817000222	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1035817000223	Bacterial transcriptional regulator; Region: IclR; pfam01614
1035817000224	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1035817000225	active sites [active]
1035817000226	tetramer interface [polypeptide binding]; other site
1035817000227	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1035817000228	Clp amino terminal domain; Region: Clp_N; pfam02861
1035817000229	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817000230	Walker A motif; other site
1035817000231	ATP binding site [chemical binding]; other site
1035817000232	Walker B motif; other site
1035817000233	arginine finger; other site
1035817000234	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817000235	Walker A motif; other site
1035817000236	ATP binding site [chemical binding]; other site
1035817000237	Walker B motif; other site
1035817000238	arginine finger; other site
1035817000239	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1035817000240	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817000241	active site
1035817000242	HIGH motif; other site
1035817000243	nucleotide binding site [chemical binding]; other site
1035817000244	active site
1035817000245	KMSKS motif; other site
1035817000246	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1035817000247	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1035817000248	active site
1035817000249	catalytic site [active]
1035817000250	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1035817000251	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817000252	active site
1035817000253	Integrase core domain; Region: rve; pfam00665
1035817000254	AAA domain; Region: AAA_14; pfam13173
1035817000255	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1035817000256	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
1035817000257	active site
1035817000258	Ap6A binding site [chemical binding]; other site
1035817000259	nudix motif; other site
1035817000260	metal binding site [ion binding]; metal-binding site
1035817000261	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817000262	catalytic core [active]
1035817000263	polyphosphate kinase; Provisional; Region: PRK05443
1035817000264	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1035817000265	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1035817000266	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1035817000267	putative domain interface [polypeptide binding]; other site
1035817000268	putative active site [active]
1035817000269	catalytic site [active]
1035817000270	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1035817000271	putative domain interface [polypeptide binding]; other site
1035817000272	putative active site [active]
1035817000273	catalytic site [active]
1035817000274	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
1035817000275	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1035817000276	putative active site [active]
1035817000277	putative metal binding site [ion binding]; other site
1035817000278	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
1035817000279	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1035817000280	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1035817000281	Bacterial transcriptional regulator; Region: IclR; pfam01614
1035817000282	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1035817000283	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1035817000284	substrate binding site [chemical binding]; other site
1035817000285	ligand binding site [chemical binding]; other site
1035817000286	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1035817000287	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1035817000288	substrate binding site [chemical binding]; other site
1035817000289	Dihydroorotate dehydrogenase (DHOD) and Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the...; Region: DHOD_DHPD_FMN; cd02810
1035817000290	active site
1035817000291	FMN binding site [chemical binding]; other site
1035817000292	substrate binding site [chemical binding]; other site
1035817000293	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1035817000294	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1035817000295	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1035817000296	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1035817000297	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1035817000298	hinge; other site
1035817000299	active site
1035817000300	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1035817000301	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817000302	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817000303	homodimer interface [polypeptide binding]; other site
1035817000304	catalytic residue [active]
1035817000305	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1035817000306	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1035817000307	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_6; cd08423
1035817000308	putative dimerization interface [polypeptide binding]; other site
1035817000309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000310	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817000311	putative substrate translocation pore; other site
1035817000312	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817000313	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817000314	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1035817000315	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1035817000316	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817000317	active site
1035817000318	HIGH motif; other site
1035817000319	nucleotide binding site [chemical binding]; other site
1035817000320	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1035817000321	KMSK motif region; other site
1035817000322	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1035817000323	tRNA binding surface [nucleotide binding]; other site
1035817000324	anticodon binding site; other site
1035817000325	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1035817000326	catalytic residue [active]
1035817000327	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1035817000328	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1035817000329	homoserine dehydrogenase; Provisional; Region: PRK06349
1035817000330	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1035817000331	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1035817000332	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1035817000333	homoserine kinase; Provisional; Region: PRK01212
1035817000334	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1035817000335	Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard...; Region: Maf_Ham1; cl00276
1035817000336	putative active site [active]
1035817000337	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1035817000338	dimer interface [polypeptide binding]; other site
1035817000339	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1035817000340	nudix motif; other site
1035817000341	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817000342	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817000343	Walker A/P-loop; other site
1035817000344	ATP binding site [chemical binding]; other site
1035817000345	Q-loop/lid; other site
1035817000346	ABC transporter signature motif; other site
1035817000347	Walker B; other site
1035817000348	D-loop; other site
1035817000349	H-loop/switch region; other site
1035817000350	Predicted permeases [General function prediction only]; Region: COG0679
1035817000351	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13007
1035817000352	M20 Peptidase actinobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_actinobac; cd05647
1035817000353	metal binding site [ion binding]; metal-binding site
1035817000354	putative dimer interface [polypeptide binding]; other site
1035817000355	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1035817000356	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1035817000357	homodimer interface [polypeptide binding]; other site
1035817000358	oligonucleotide binding site [chemical binding]; other site
1035817000359	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1035817000360	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1035817000361	GTPase CgtA; Reviewed; Region: obgE; PRK12296
1035817000362	GTP1/OBG; Region: GTP1_OBG; pfam01018
1035817000363	Obg GTPase; Region: Obg; cd01898
1035817000364	G1 box; other site
1035817000365	GTP/Mg2+ binding site [chemical binding]; other site
1035817000366	Switch I region; other site
1035817000367	G2 box; other site
1035817000368	G3 box; other site
1035817000369	Switch II region; other site
1035817000370	G4 box; other site
1035817000371	G5 box; other site
1035817000372	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1035817000373	gamma-glutamyl kinase; Provisional; Region: PRK05429
1035817000374	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1035817000375	nucleotide binding site [chemical binding]; other site
1035817000376	homotetrameric interface [polypeptide binding]; other site
1035817000377	putative phosphate binding site [ion binding]; other site
1035817000378	putative allosteric binding site; other site
1035817000379	PUA domain; Region: PUA; pfam01472
1035817000380	aspartate aminotransferase; Provisional; Region: PRK05764
1035817000381	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817000382	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817000383	homodimer interface [polypeptide binding]; other site
1035817000384	catalytic residue [active]
1035817000385	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1035817000386	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1035817000387	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1035817000388	putative homodimer interface [polypeptide binding]; other site
1035817000389	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1035817000390	heterodimer interface [polypeptide binding]; other site
1035817000391	homodimer interface [polypeptide binding]; other site
1035817000392	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1035817000393	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1035817000394	23S rRNA interface [nucleotide binding]; other site
1035817000395	L7/L12 interface [polypeptide binding]; other site
1035817000396	putative thiostrepton binding site; other site
1035817000397	L25 interface [polypeptide binding]; other site
1035817000398	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1035817000399	mRNA/rRNA interface [nucleotide binding]; other site
1035817000400	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1035817000401	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1035817000402	Bacterial transcriptional regulator; Region: IclR; pfam01614
1035817000403	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1035817000404	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
1035817000405	Bacterial transcriptional regulator; Region: IclR; pfam01614
1035817000406	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1035817000407	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1035817000408	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1035817000409	BioY family; Region: BioY; pfam02632
1035817000410	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
1035817000411	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1035817000412	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1035817000413	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
1035817000414	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1035817000415	carboxyltransferase (CT) interaction site; other site
1035817000416	biotinylation site [posttranslational modification]; other site
1035817000417	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1035817000418	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1035817000419	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1035817000420	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1035817000421	Enoyl reductase domain of yeast-type FAS1 [Lipid metabolism]; Region: COG4981
1035817000422	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1035817000423	phosphate binding site [ion binding]; other site
1035817000424	Domain of unknown function (DUF1729); Region: DUF1729; pfam08354
1035817000425	FAS_MaoC, the MaoC-like hot dog fold of the fatty acid synthase, beta subunit.  Other enzymes with this fold include MaoC dehydratase, Hydratase-Dehydrogenase-Epimerase protein (HDE), and 17-beta-hydroxysteriod dehydrogenase (HSD); Region: FAS_MaoC; cd03447
1035817000426	putative active site [active]
1035817000427	putative catalytic site [active]
1035817000428	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1035817000429	3-oxoacyl-[acyl-carrier protein]; Region: COG4982
1035817000430	ketoacyl reductase (KR) domain of fungal-type fatty acid synthase (fFAS), classical (c)-like SDRs; Region: KR_fFAS_SDR_c_like; cd08950
1035817000431	putative NAD(P) binding site [chemical binding]; other site
1035817000432	active site
1035817000433	"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP)...; Region: elong_cond_enzymes; cd00828
1035817000434	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1035817000435	active site
1035817000436	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1035817000437	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1035817000438	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1035817000439	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
1035817000440	substrate binding site [chemical binding]; other site
1035817000441	active site
1035817000442	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
1035817000443	metal binding site [ion binding]; metal-binding site
1035817000444	ligand binding site [chemical binding]; other site
1035817000445	Uncharacterized Sugar-binding Domain; Region: FIVAR; pfam07554
1035817000446	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
1035817000447	active site
1035817000448	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1035817000449	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817000450	Integrase core domain; Region: rve; pfam00665
1035817000451	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1035817000452	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1035817000453	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1035817000454	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1035817000455	Walker A/P-loop; other site
1035817000456	ATP binding site [chemical binding]; other site
1035817000457	Q-loop/lid; other site
1035817000458	ABC transporter signature motif; other site
1035817000459	Walker B; other site
1035817000460	D-loop; other site
1035817000461	H-loop/switch region; other site
1035817000462	ABC transporter; Region: ABC_tran; pfam00005
1035817000463	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000464	Q-loop/lid; other site
1035817000465	ABC transporter signature motif; other site
1035817000466	Walker B; other site
1035817000467	D-loop; other site
1035817000468	H-loop/switch region; other site
1035817000469	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1035817000470	16S/18S rRNA binding site [nucleotide binding]; other site
1035817000471	S13e-L30e interaction site [polypeptide binding]; other site
1035817000472	25S rRNA binding site [nucleotide binding]; other site
1035817000473	guanosine pentaphosphate synthetase I/polynucleotide phosphorylase; Region: pppGpp_PNP; TIGR02696
1035817000474	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1035817000475	oligomer interface [polypeptide binding]; other site
1035817000476	RNA binding site [nucleotide binding]; other site
1035817000477	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1035817000478	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1035817000479	RNase E interface [polypeptide binding]; other site
1035817000480	trimer interface [polypeptide binding]; other site
1035817000481	active site
1035817000482	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1035817000483	putative nucleic acid binding region [nucleotide binding]; other site
1035817000484	G-X-X-G motif; other site
1035817000485	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1035817000486	RNA binding site [nucleotide binding]; other site
1035817000487	domain interface; other site
1035817000488	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1035817000489	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1035817000490	23S rRNA interface [nucleotide binding]; other site
1035817000491	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1035817000492	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1035817000493	peripheral dimer interface [polypeptide binding]; other site
1035817000494	core dimer interface [polypeptide binding]; other site
1035817000495	L10 interface [polypeptide binding]; other site
1035817000496	L11 interface [polypeptide binding]; other site
1035817000497	putative EF-Tu interaction site [polypeptide binding]; other site
1035817000498	putative EF-G interaction site [polypeptide binding]; other site
1035817000499	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1035817000500	phosphopeptide binding site; other site
1035817000501	Part of AAA domain; Region: AAA_19; pfam13245
1035817000502	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1035817000503	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
1035817000504	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1035817000505	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1035817000506	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1035817000507	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1035817000508	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1035817000509	oligomerisation interface [polypeptide binding]; other site
1035817000510	mobile loop; other site
1035817000511	roof hairpin; other site
1035817000512	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817000513	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817000514	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1035817000515	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13903
1035817000516	FAD binding domain; Region: FAD_binding_4; pfam01565
1035817000517	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1035817000518	amino acid transporter; Region: 2A0306; TIGR00909
1035817000519	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1035817000520	Ferredoxin [Energy production and conversion]; Region: COG1146
1035817000521	4Fe-4S binding domain; Region: Fer4; pfam00037
1035817000522	N-succinyldiaminopimelate aminotransferase; Reviewed; Region: PRK07865
1035817000523	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817000524	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817000525	homodimer interface [polypeptide binding]; other site
1035817000526	catalytic residue [active]
1035817000527	DNA polymerase IV; Validated; Region: PRK03858
1035817000528	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1035817000529	active site
1035817000530	DNA binding site [nucleotide binding]
1035817000531	Threonine/homoserine efflux transporter [Amino acid transport and metabolism]; Region: rhtA; COG5006
1035817000532	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1035817000533	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1035817000534	putative active site [active]
1035817000535	putative metal binding site [ion binding]; other site
1035817000536	Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169
1035817000537	dimerization interface [polypeptide binding]; other site
1035817000538	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1035817000539	NAD binding site [chemical binding]; other site
1035817000540	ligand binding site [chemical binding]; other site
1035817000541	catalytic site [active]
1035817000542	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1035817000543	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1035817000544	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1035817000545	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1035817000546	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1035817000547	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1035817000548	23S rRNA interface [nucleotide binding]; other site
1035817000549	L3 interface [polypeptide binding]; other site
1035817000550	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1035817000551	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1035817000552	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1035817000553	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1035817000554	active site
1035817000555	catalytic site [active]
1035817000556	L-threonine dehydrogenase; Region: threonine_DH_like; cd08234
1035817000557	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1035817000558	putative NAD(P) binding site [chemical binding]; other site
1035817000559	catalytic Zn binding site [ion binding]; other site
1035817000560	polyol permease family; Region: 2A0118; TIGR00897
1035817000561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000562	putative substrate translocation pore; other site
1035817000563	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1035817000564	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1035817000565	active site
1035817000566	metal binding site [ion binding]; metal-binding site
1035817000567	polyol permease family; Region: 2A0118; TIGR00897
1035817000568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000569	putative substrate translocation pore; other site
1035817000570	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1035817000571	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1035817000572	inhibitor binding site; inhibition site
1035817000573	catalytic Zn binding site [ion binding]; other site
1035817000574	structural Zn binding site [ion binding]; other site
1035817000575	NADP binding site [chemical binding]; other site
1035817000576	tetramer interface [polypeptide binding]; other site
1035817000577	Helix-turn-helix domain; Region: HTH_18; pfam12833
1035817000578	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1035817000579	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1035817000580	non-specific DNA interactions [nucleotide binding]; other site
1035817000581	DNA binding site [nucleotide binding]
1035817000582	sequence specific DNA binding site [nucleotide binding]; other site
1035817000583	putative cAMP binding site [chemical binding]; other site
1035817000584	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817000585	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817000586	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1035817000587	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1035817000588	putative catalytic cysteine [active]
1035817000589	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1035817000590	putative active site [active]
1035817000591	metal binding site [ion binding]; metal-binding site
1035817000592	YwiC-like protein; Region: YwiC; pfam14256
1035817000593	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1035817000594	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1035817000595	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1035817000596	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1035817000597	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1035817000598	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1035817000599	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1035817000600	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1035817000601	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1035817000602	putative translocon binding site; other site
1035817000603	protein-rRNA interface [nucleotide binding]; other site
1035817000604	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1035817000605	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1035817000606	G-X-X-G motif; other site
1035817000607	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1035817000608	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1035817000609	23S rRNA interface [nucleotide binding]; other site
1035817000610	5S rRNA interface [nucleotide binding]; other site
1035817000611	putative antibiotic binding site [chemical binding]; other site
1035817000612	L25 interface [polypeptide binding]; other site
1035817000613	L27 interface [polypeptide binding]; other site
1035817000614	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1035817000615	23S rRNA interface [nucleotide binding]; other site
1035817000616	putative translocon interaction site; other site
1035817000617	signal recognition particle (SRP54) interaction site; other site
1035817000618	L23 interface [polypeptide binding]; other site
1035817000619	trigger factor interaction site; other site
1035817000620	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1035817000621	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1035817000622	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1035817000623	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1035817000624	RNA binding site [nucleotide binding]; other site
1035817000625	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1035817000626	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1035817000627	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1035817000628	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1035817000629	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1035817000630	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1035817000631	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1035817000632	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1035817000633	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1035817000634	23S rRNA interface [nucleotide binding]; other site
1035817000635	L21e interface [polypeptide binding]; other site
1035817000636	5S rRNA interface [nucleotide binding]; other site
1035817000637	L27 interface [polypeptide binding]; other site
1035817000638	L5 interface [polypeptide binding]; other site
1035817000639	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1035817000640	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1035817000641	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1035817000642	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1035817000643	23S rRNA binding site [nucleotide binding]; other site
1035817000644	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1035817000645	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1035817000646	SecY translocase; Region: SecY; pfam00344
1035817000647	adenylate kinase; Reviewed; Region: adk; PRK00279
1035817000648	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1035817000649	AMP-binding site [chemical binding]; other site
1035817000650	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1035817000651	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1035817000652	rRNA binding site [nucleotide binding]; other site
1035817000653	predicted 30S ribosome binding site; other site
1035817000654	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1035817000655	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1035817000656	30S ribosomal protein S11; Validated; Region: PRK05309
1035817000657	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1035817000658	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1035817000659	alphaNTD homodimer interface [polypeptide binding]; other site
1035817000660	alphaNTD - beta interaction site [polypeptide binding]; other site
1035817000661	alphaNTD - beta' interaction site [polypeptide binding]; other site
1035817000662	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1035817000663	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1035817000664	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1035817000665	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1035817000666	dimerization interface 3.5A [polypeptide binding]; other site
1035817000667	active site
1035817000668	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
1035817000669	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
1035817000670	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1035817000671	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1035817000672	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1035817000673	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1035817000674	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1035817000675	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817000676	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817000677	DNA binding site [nucleotide binding]
1035817000678	domain linker motif; other site
1035817000679	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817000680	dimerization interface [polypeptide binding]; other site
1035817000681	ligand binding site [chemical binding]; other site
1035817000682	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1035817000683	NusA N-terminal domain; Region: NusA_N; pfam08529
1035817000684	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1035817000685	RNA binding site [nucleotide binding]; other site
1035817000686	homodimer interface [polypeptide binding]; other site
1035817000687	NusA-like KH domain; Region: KH_5; pfam13184
1035817000688	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1035817000689	G-X-X-G motif; other site
1035817000690	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1035817000691	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1035817000692	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
1035817000693	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1035817000694	G1 box; other site
1035817000695	putative GEF interaction site [polypeptide binding]; other site
1035817000696	GTP/Mg2+ binding site [chemical binding]; other site
1035817000697	Switch I region; other site
1035817000698	G2 box; other site
1035817000699	G3 box; other site
1035817000700	Switch II region; other site
1035817000701	G4 box; other site
1035817000702	G5 box; other site
1035817000703	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1035817000704	Translation-initiation factor 2; Region: IF-2; pfam11987
1035817000705	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1035817000706	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1035817000707	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK03287
1035817000708	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1035817000709	RNA binding site [nucleotide binding]; other site
1035817000710	active site
1035817000711	tRNA Pseudouridine synthase II, C terminal; Region: TruB_C; pfam09142
1035817000712	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1035817000713	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1035817000714	active site
1035817000715	Riboflavin kinase; Region: Flavokinase; pfam01687
1035817000716	DNA repair protein RadA; Provisional; Region: PRK11823
1035817000717	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1035817000718	Walker A motif; other site
1035817000719	ATP binding site [chemical binding]; other site
1035817000720	Walker B motif; other site
1035817000721	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1035817000722	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1035817000723	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1035817000724	active site
1035817000725	dimer interface [polypeptide binding]; other site
1035817000726	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1035817000727	RNA/DNA hybrid binding site [nucleotide binding]; other site
1035817000728	active site
1035817000729	dihydrolipoamide dehydrogenase; Validated; Region: acoL; PRK06912
1035817000730	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1035817000731	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1035817000732	Transcriptional regulator; Region: Rrf2; pfam02082
1035817000733	Rrf2 family protein; Region: rrf2_super; TIGR00738
1035817000734	phosphoglucomutase; Validated; Region: PRK07564
1035817000735	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1035817000736	active site
1035817000737	substrate binding site [chemical binding]; other site
1035817000738	metal binding site [ion binding]; metal-binding site
1035817000739	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000740	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1035817000741	putative substrate translocation pore; other site
1035817000742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000743	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1035817000744	active site turn [active]
1035817000745	phosphorylation site [posttranslational modification]
1035817000746	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1035817000747	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1035817000748	HPr interaction site; other site
1035817000749	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1035817000750	active site
1035817000751	phosphorylation site [posttranslational modification]
1035817000752	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1035817000753	CAT RNA binding domain; Region: CAT_RBD; smart01061
1035817000754	PRD domain; Region: PRD; pfam00874
1035817000755	PRD domain; Region: PRD; pfam00874
1035817000756	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1035817000757	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1035817000758	seryl-tRNA synthetase; Provisional; Region: PRK05431
1035817000759	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1035817000760	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1035817000761	dimer interface [polypeptide binding]; other site
1035817000762	active site
1035817000763	motif 1; other site
1035817000764	motif 2; other site
1035817000765	motif 3; other site
1035817000766	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817000767	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817000768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817000769	dimer interface [polypeptide binding]; other site
1035817000770	conserved gate region; other site
1035817000771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1035817000772	ABC-ATPase subunit interface; other site
1035817000773	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817000774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817000775	dimer interface [polypeptide binding]; other site
1035817000776	conserved gate region; other site
1035817000777	putative PBP binding loops; other site
1035817000778	ABC-ATPase subunit interface; other site
1035817000779	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Region: TIGR02336
1035817000780	Lacto-N-biose phosphorylase; Region: Lact_bio_phlase; pfam09508
1035817000781	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1035817000782	Phosphotransferase enzyme family; Region: APH; pfam01636
1035817000783	active site
1035817000784	substrate binding site [chemical binding]; other site
1035817000785	ATP binding site [chemical binding]; other site
1035817000786	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1035817000787	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
1035817000788	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
1035817000789	UDP-glucose 4-epimerase; Region: PLN02240
1035817000790	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1035817000791	NAD binding site [chemical binding]; other site
1035817000792	homodimer interface [polypeptide binding]; other site
1035817000793	active site
1035817000794	substrate binding site [chemical binding]; other site
1035817000795	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817000796	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817000797	active site
1035817000798	phosphorylation site [posttranslational modification]
1035817000799	intermolecular recognition site; other site
1035817000800	dimerization interface [polypeptide binding]; other site
1035817000801	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1035817000802	DNA binding residues [nucleotide binding]
1035817000803	dimerization interface [polypeptide binding]; other site
1035817000804	PspC domain; Region: PspC; pfam04024
1035817000805	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1035817000806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817000807	ATP binding site [chemical binding]; other site
1035817000808	Mg2+ binding site [ion binding]; other site
1035817000809	G-X-G motif; other site
1035817000810	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1035817000811	Protein of unknown function (DUF4125); Region: DUF4125; pfam13526
1035817000812	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1035817000813	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1035817000814	binding surface
1035817000815	TPR motif; other site
1035817000816	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1035817000817	Domain of unknown function (DUF4037); Region: DUF4037; pfam13228
1035817000818	MFS transport protein AraJ; Provisional; Region: PRK10091
1035817000819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817000820	putative substrate translocation pore; other site
1035817000821	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1035817000822	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1035817000823	dimer interface [polypeptide binding]; other site
1035817000824	putative anticodon binding site; other site
1035817000825	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1035817000826	motif 1; other site
1035817000827	dimer interface [polypeptide binding]; other site
1035817000828	active site
1035817000829	motif 2; other site
1035817000830	motif 3; other site
1035817000831	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1035817000832	UbiA prenyltransferase family; Region: UbiA; pfam01040
1035817000833	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817000834	catalytic core [active]
1035817000835	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1035817000836	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1035817000837	PhoU domain; Region: PhoU; pfam01895
1035817000838	PhoU domain; Region: PhoU; pfam01895
1035817000839	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1035817000840	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817000841	ATP binding site [chemical binding]; other site
1035817000842	Mg2+ binding site [ion binding]; other site
1035817000843	G-X-G motif; other site
1035817000844	phosphoserine aminotransferase; Provisional; Region: PRK03080
1035817000845	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1035817000846	catalytic residue [active]
1035817000847	CHAP domain; Region: CHAP; pfam05257
1035817000848	NlpC/P60 family; Region: NLPC_P60; cl17555
1035817000849	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1035817000850	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1035817000851	NlpC/P60 family; Region: NLPC_P60; pfam00877
1035817000852	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1035817000853	Ligand Binding Site [chemical binding]; other site
1035817000854	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1035817000855	Ligand Binding Site [chemical binding]; other site
1035817000856	OsmC-like protein; Region: OsmC; pfam02566
1035817000857	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1035817000858	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1035817000859	dimerization interface [polypeptide binding]; other site
1035817000860	active site
1035817000861	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1035817000862	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1035817000863	folate binding site [chemical binding]; other site
1035817000864	NADP+ binding site [chemical binding]; other site
1035817000865	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1035817000866	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1035817000867	active site
1035817000868	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1035817000869	AzlC protein; Region: AzlC; cl00570
1035817000870	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817000871	Int/Topo IB signature motif; other site
1035817000872	DNA binding site [nucleotide binding]
1035817000873	active site
1035817000874	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817000875	Integrase core domain; Region: rve; pfam00665
1035817000876	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817000877	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1035817000878	Walker A motif; other site
1035817000879	ATP binding site [chemical binding]; other site
1035817000880	Walker B motif; other site
1035817000881	arginine finger; other site
1035817000882	MULE transposase domain; Region: MULE; pfam10551
1035817000883	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1035817000884	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1035817000885	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1035817000886	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1035817000887	catalytic residue [active]
1035817000888	Surface antigen [General function prediction only]; Region: COG3942
1035817000889	CHAP domain; Region: CHAP; pfam05257
1035817000890	similar to truncated type IV secretory pathway VirB4 component protein; BLNIAS_00424; virB4
1035817000891	PrgI family protein; Region: PrgI; pfam12666
1035817000892	potential frameshift: common BLAST hit: gi|213691429|ref|YP_002322015.1| LPXTG-motif cell wall anchor domain-containing protein
1035817000893	adhesin isopeptide-forming domain, sspB-C2 type; Region: isopep_sspB_C2; TIGR04228
1035817000894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000895	Walker A/P-loop; other site
1035817000896	ATP binding site [chemical binding]; other site
1035817000897	AAA domain; Region: AAA_21; pfam13304
1035817000898	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817000899	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
1035817000900	P-loop; other site
1035817000901	Magnesium ion binding site [ion binding]; other site
1035817000902	hypothetical protein; Region: PHA01623
1035817000903	Transcription factor WhiB; Region: Whib; pfam02467
1035817000904	Helix-turn-helix domain; Region: HTH_36; pfam13730
1035817000905	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1035817000906	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1035817000907	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1035817000908	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1035817000909	NAD(P) binding site [chemical binding]; other site
1035817000910	active site
1035817000911	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
1035817000912	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817000913	S-adenosylmethionine binding site [chemical binding]; other site
1035817000914	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1035817000915	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1035817000916	dimer interface [polypeptide binding]; other site
1035817000917	active site
1035817000918	metal binding site [ion binding]; metal-binding site
1035817000919	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1035817000920	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1035817000921	active site
1035817000922	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1035817000923	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1035817000924	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1035817000925	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
1035817000926	DXD motif; other site
1035817000927	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1035817000928	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1035817000929	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1035817000930	Walker A/P-loop; other site
1035817000931	ATP binding site [chemical binding]; other site
1035817000932	Q-loop/lid; other site
1035817000933	ABC transporter signature motif; other site
1035817000934	Walker B; other site
1035817000935	D-loop; other site
1035817000936	H-loop/switch region; other site
1035817000937	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
1035817000938	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1035817000939	Ligand Binding Site [chemical binding]; other site
1035817000940	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1035817000941	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817000942	active site
1035817000943	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1035817000944	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817000945	Walker A motif; other site
1035817000946	ATP binding site [chemical binding]; other site
1035817000947	Walker B motif; other site
1035817000948	arginine finger; other site
1035817000949	Peptidase family M41; Region: Peptidase_M41; pfam01434
1035817000950	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1035817000951	GTP cyclohydrolase I; Provisional; Region: PLN03044
1035817000952	active site
1035817000953	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1035817000954	dihydropteroate synthase; Region: DHPS; TIGR01496
1035817000955	substrate binding pocket [chemical binding]; other site
1035817000956	dimer interface [polypeptide binding]; other site
1035817000957	inhibitor binding site; inhibition site
1035817000958	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1035817000959	homooctamer interface [polypeptide binding]; other site
1035817000960	active site
1035817000961	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1035817000962	catalytic center binding site [active]
1035817000963	ATP binding site [chemical binding]; other site
1035817000964	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cl00233
1035817000965	catalytic center binding site [active]
1035817000966	ATP binding site [chemical binding]; other site
1035817000967	Protein of unknown function (DUF3180); Region: DUF3180; pfam11377
1035817000968	Acyl-CoA thioesterase [Lipid metabolism]; Region: TesB; COG1946
1035817000969	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1035817000970	active site
1035817000971	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1035817000972	catalytic triad [active]
1035817000973	dimer interface [polypeptide binding]; other site
1035817000974	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1035817000975	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817000976	Walker A/P-loop; other site
1035817000977	ATP binding site [chemical binding]; other site
1035817000978	Q-loop/lid; other site
1035817000979	ABC transporter signature motif; other site
1035817000980	Walker B; other site
1035817000981	D-loop; other site
1035817000982	H-loop/switch region; other site
1035817000983	ABC transporter; Region: ABC_tran_2; pfam12848
1035817000984	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1035817000985	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1035817000986	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817000987	nucleotide binding site [chemical binding]; other site
1035817000988	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1035817000989	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1035817000990	Walker A/P-loop; other site
1035817000991	ATP binding site [chemical binding]; other site
1035817000992	Q-loop/lid; other site
1035817000993	ABC transporter signature motif; other site
1035817000994	Walker B; other site
1035817000995	D-loop; other site
1035817000996	H-loop/switch region; other site
1035817000997	MarR family; Region: MarR_2; pfam12802
1035817000998	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817000999	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817001000	nucleotide binding site [chemical binding]; other site
1035817001001	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817001002	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
1035817001003	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1035817001004	putative ligand binding site [chemical binding]; other site
1035817001005	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1035817001006	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1035817001007	Walker A/P-loop; other site
1035817001008	ATP binding site [chemical binding]; other site
1035817001009	Q-loop/lid; other site
1035817001010	ABC transporter signature motif; other site
1035817001011	Walker B; other site
1035817001012	D-loop; other site
1035817001013	H-loop/switch region; other site
1035817001014	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1035817001015	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1035817001016	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1035817001017	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1035817001018	TM-ABC transporter signature motif; other site
1035817001019	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1035817001020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001021	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817001022	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817001023	active site
1035817001024	catalytic tetrad [active]
1035817001025	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1035817001026	active site
1035817001027	catalytic residues [active]
1035817001028	metal binding site [ion binding]; metal-binding site
1035817001029	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1035817001030	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1035817001031	xylose isomerase; Provisional; Region: PRK05474
1035817001032	xylose isomerase; Region: xylose_isom_A; TIGR02630
1035817001033	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1035817001034	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1035817001035	dimer interface [polypeptide binding]; other site
1035817001036	active site
1035817001037	metal binding site [ion binding]; metal-binding site
1035817001038	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817001039	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817001040	DNA binding site [nucleotide binding]
1035817001041	Ligand-binding domain of a LacI-like transcriptional regulator, CatR which is involved in catechol degradation; Region: PBP1_CatR_like; cd06296
1035817001042	putative dimerization interface [polypeptide binding]; other site
1035817001043	putative ligand binding site [chemical binding]; other site
1035817001044	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817001045	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817001046	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1035817001047	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001048	dimer interface [polypeptide binding]; other site
1035817001049	conserved gate region; other site
1035817001050	putative PBP binding loops; other site
1035817001051	ABC-ATPase subunit interface; other site
1035817001052	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817001053	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001054	dimer interface [polypeptide binding]; other site
1035817001055	conserved gate region; other site
1035817001056	putative PBP binding loops; other site
1035817001057	ABC-ATPase subunit interface; other site
1035817001058	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1035817001059	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1035817001060	inhibitor binding site; inhibition site
1035817001061	active site
1035817001062	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
1035817001063	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1035817001064	active site
1035817001065	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1035817001066	trimer interface [polypeptide binding]; other site
1035817001067	active site
1035817001068	substrate binding site [chemical binding]; other site
1035817001069	CoA binding site [chemical binding]; other site
1035817001070	Right handed beta helix region; Region: Beta_helix; pfam13229
1035817001071	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
1035817001072	N- and C-terminal domain interface [polypeptide binding]; other site
1035817001073	D-xylulose kinase; Region: XylB; TIGR01312
1035817001074	active site
1035817001075	MgATP binding site [chemical binding]; other site
1035817001076	catalytic site [active]
1035817001077	metal binding site [ion binding]; metal-binding site
1035817001078	xylulose binding site [chemical binding]; other site
1035817001079	putative homodimer interface [polypeptide binding]; other site
1035817001080	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1035817001081	non-specific DNA interactions [nucleotide binding]; other site
1035817001082	DNA binding site [nucleotide binding]
1035817001083	sequence specific DNA binding site [nucleotide binding]; other site
1035817001084	putative cAMP binding site [chemical binding]; other site
1035817001085	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817001086	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817001087	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1035817001088	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1035817001089	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1035817001090	RF-1 domain; Region: RF-1; pfam00472
1035817001091	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1035817001092	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817001093	S-adenosylmethionine binding site [chemical binding]; other site
1035817001094	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1035817001095	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1035817001096	putative ligand binding site [chemical binding]; other site
1035817001097	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1035817001098	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1035817001099	TM-ABC transporter signature motif; other site
1035817001100	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1035817001101	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1035817001102	TM-ABC transporter signature motif; other site
1035817001103	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1035817001104	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1035817001105	Walker A/P-loop; other site
1035817001106	ATP binding site [chemical binding]; other site
1035817001107	Q-loop/lid; other site
1035817001108	ABC transporter signature motif; other site
1035817001109	Walker B; other site
1035817001110	D-loop; other site
1035817001111	H-loop/switch region; other site
1035817001112	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1035817001113	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1035817001114	Walker A/P-loop; other site
1035817001115	ATP binding site [chemical binding]; other site
1035817001116	Q-loop/lid; other site
1035817001117	ABC transporter signature motif; other site
1035817001118	Walker B; other site
1035817001119	D-loop; other site
1035817001120	H-loop/switch region; other site
1035817001121	maltose O-acetyltransferase; Provisional; Region: PRK10092
1035817001122	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1035817001123	active site
1035817001124	substrate binding site [chemical binding]; other site
1035817001125	trimer interface [polypeptide binding]; other site
1035817001126	CoA binding site [chemical binding]; other site
1035817001127	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1035817001128	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1035817001129	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1035817001130	Mg++ binding site [ion binding]; other site
1035817001131	putative catalytic motif [active]
1035817001132	substrate binding site [chemical binding]; other site
1035817001133	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1035817001134	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1035817001135	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1035817001136	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1035817001137	active site
1035817001138	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1035817001139	catalytic site [active]
1035817001140	putative active site [active]
1035817001141	putative substrate binding site [chemical binding]; other site
1035817001142	dimer interface [polypeptide binding]; other site
1035817001143	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001144	PIF1-like helicase; Region: PIF1; pfam05970
1035817001145	Walker A motif; other site
1035817001146	ATP binding site [chemical binding]; other site
1035817001147	Walker B motif; other site
1035817001148	arginine finger; other site
1035817001149	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1035817001150	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
1035817001151	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817001152	MULE transposase domain; Region: MULE; pfam10551
1035817001153	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1035817001154	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1035817001155	dimer interface [polypeptide binding]; other site
1035817001156	motif 1; other site
1035817001157	active site
1035817001158	motif 2; other site
1035817001159	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
1035817001160	putative deacylase active site [active]
1035817001161	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1035817001162	active site
1035817001163	motif 3; other site
1035817001164	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1035817001165	anticodon binding site; other site
1035817001166	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1035817001167	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1035817001168	dimer interface [polypeptide binding]; other site
1035817001169	ssDNA binding site [nucleotide binding]; other site
1035817001170	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1035817001171	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1035817001172	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1035817001173	active site
1035817001174	Zn binding site [ion binding]; other site
1035817001175	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
1035817001176	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1035817001177	active site
1035817001178	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
1035817001179	Citrate synthase; Region: Citrate_synt; pfam00285
1035817001180	oxalacetate binding site [chemical binding]; other site
1035817001181	citrylCoA binding site [chemical binding]; other site
1035817001182	coenzyme A binding site [chemical binding]; other site
1035817001183	catalytic triad [active]
1035817001184	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Region: DapD_actino; TIGR03535
1035817001185	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1035817001186	putative trimer interface [polypeptide binding]; other site
1035817001187	putative CoA binding site [chemical binding]; other site
1035817001188	WYL domain; Region: WYL; pfam13280
1035817001189	SWIM zinc finger; Region: SWIM; pfam04434
1035817001190	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1035817001191	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1035817001192	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817001193	ATP binding site [chemical binding]; other site
1035817001194	putative Mg++ binding site [ion binding]; other site
1035817001195	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817001196	nucleotide binding region [chemical binding]; other site
1035817001197	ATP-binding site [chemical binding]; other site
1035817001198	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1035817001199	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817001200	Coenzyme A binding pocket [chemical binding]; other site
1035817001201	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1035817001202	additional DNA contacts [nucleotide binding]; other site
1035817001203	mismatch recognition site; other site
1035817001204	active site
1035817001205	zinc binding site [ion binding]; other site
1035817001206	DNA intercalation site [nucleotide binding]; other site
1035817001207	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1035817001208	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1035817001209	aminotransferase; Validated; Region: PRK07337
1035817001210	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817001211	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817001212	homodimer interface [polypeptide binding]; other site
1035817001213	catalytic residue [active]
1035817001214	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1035817001215	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817001216	nucleotide binding site [chemical binding]; other site
1035817001217	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1035817001218	putative catalytic site [active]
1035817001219	putative metal binding site [ion binding]; other site
1035817001220	putative phosphate binding site [ion binding]; other site
1035817001221	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1035817001222	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817001223	Coenzyme A binding pocket [chemical binding]; other site
1035817001224	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
1035817001225	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1035817001226	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1035817001227	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1035817001228	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1035817001229	acyl-activating enzyme (AAE) consensus motif; other site
1035817001230	putative AMP binding site [chemical binding]; other site
1035817001231	putative active site [active]
1035817001232	putative CoA binding site [chemical binding]; other site
1035817001233	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1035817001234	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1035817001235	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1035817001236	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1035817001237	generic binding surface II; other site
1035817001238	generic binding surface I; other site
1035817001239	oxidoreductase; Region: PLN02835
1035817001240	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1035817001241	ATP cone domain; Region: ATP-cone; pfam03477
1035817001242	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1035817001243	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1035817001244	active site
1035817001245	Zn binding site [ion binding]; other site
1035817001246	glycine loop; other site
1035817001247	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1035817001248	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1035817001249	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1035817001250	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1035817001251	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1035817001252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
1035817001253	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1035817001254	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1035817001255	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1035817001256	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
1035817001257	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817001258	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817001259	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1035817001260	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1035817001261	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1035817001262	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1035817001263	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1035817001264	Winged helix-turn helix; Region: HTH_29; pfam13551
1035817001265	DNA-binding interface [nucleotide binding]; DNA binding site
1035817001266	Integrase core domain; Region: rve; pfam00665
1035817001267	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1035817001268	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1035817001269	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1035817001270	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817001271	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1035817001272	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1035817001273	active site
1035817001274	catalytic triad [active]
1035817001275	dimer interface [polypeptide binding]; other site
1035817001276	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1035817001277	Amidase; Region: Amidase; cl11426
1035817001278	OsmC-like protein; Region: OsmC; pfam02566
1035817001279	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817001280	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817001281	DNA binding site [nucleotide binding]
1035817001282	domain linker motif; other site
1035817001283	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817001284	dimerization interface [polypeptide binding]; other site
1035817001285	ligand binding site [chemical binding]; other site
1035817001286	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817001287	MULE transposase domain; Region: MULE; pfam10551
1035817001288	MgtC family; Region: MgtC; pfam02308
1035817001289	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1035817001290	active site
1035817001291	NTP binding site [chemical binding]; other site
1035817001292	metal binding triad [ion binding]; metal-binding site
1035817001293	antibiotic binding site [chemical binding]; other site
1035817001294	nucleotidyltransferase substrate binding protein, HI0074 family; Region: HI0074; TIGR01987
1035817001295	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1035817001296	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817001297	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817001298	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001299	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817001300	putative substrate translocation pore; other site
1035817001301	putative hydrolase, CocE/NonD family; Region: /NonD; TIGR00976
1035817001302	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1035817001303	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1035817001304	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1035817001305	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817001306	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817001307	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1035817001308	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1035817001309	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1035817001310	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1035817001311	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1035817001312	MarR family; Region: MarR_2; pfam12802
1035817001313	MarR family; Region: MarR_2; cl17246
1035817001314	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817001315	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817001316	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817001317	Walker A/P-loop; other site
1035817001318	ATP binding site [chemical binding]; other site
1035817001319	Q-loop/lid; other site
1035817001320	ABC transporter signature motif; other site
1035817001321	Walker B; other site
1035817001322	D-loop; other site
1035817001323	H-loop/switch region; other site
1035817001324	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
1035817001325	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817001326	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1035817001327	Walker A/P-loop; other site
1035817001328	ATP binding site [chemical binding]; other site
1035817001329	Q-loop/lid; other site
1035817001330	ABC transporter signature motif; other site
1035817001331	Walker B; other site
1035817001332	D-loop; other site
1035817001333	H-loop/switch region; other site
1035817001334	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817001335	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817001336	DNA binding site [nucleotide binding]
1035817001337	domain linker motif; other site
1035817001338	Ligand-binding domain of DNA-binding regulatory protein from Corynebacterium glutamicum which has a unique ability to produce significant amounts of L-glutamate directly from cheap sugar and ammonia; Region: PBP1_LacI_like_13; cd06299
1035817001339	dimerization interface [polypeptide binding]; other site
1035817001340	putative ligand binding site [chemical binding]; other site
1035817001341	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1035817001342	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817001343	Coenzyme A binding pocket [chemical binding]; other site
1035817001344	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1035817001345	active site
1035817001346	tetramer interface [polypeptide binding]; other site
1035817001347	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; cl17322
1035817001348	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1035817001349	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1035817001350	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1035817001351	substrate binding site [chemical binding]; other site
1035817001352	dimer interface [polypeptide binding]; other site
1035817001353	ATP binding site [chemical binding]; other site
1035817001354	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817001355	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817001356	DNA binding site [nucleotide binding]
1035817001357	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1035817001358	putative dimerization interface [polypeptide binding]; other site
1035817001359	putative ligand binding site [chemical binding]; other site
1035817001360	similar to fragment of beta galactosidase; BLNIAS_00643
1035817001361	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1035817001362	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817001363	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817001364	homodimer interface [polypeptide binding]; other site
1035817001365	catalytic residue [active]
1035817001366	Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: IleS; COG0060
1035817001367	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1035817001368	HIGH motif; other site
1035817001369	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1035817001370	active site
1035817001371	KMSKS motif; other site
1035817001372	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1035817001373	tRNA binding surface [nucleotide binding]; other site
1035817001374	anticodon binding site; other site
1035817001375	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1035817001376	Int/Topo IB signature motif; other site
1035817001377	similar to truncated endonuclease; BLNIAS_00651
1035817001378	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1035817001379	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1035817001380	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1035817001381	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1035817001382	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1035817001383	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1035817001384	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1035817001385	Divergent AAA domain; Region: AAA_4; pfam04326
1035817001386	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1035817001387	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1035817001388	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1035817001389	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1035817001390	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817001391	ATP binding site [chemical binding]; other site
1035817001392	putative Mg++ binding site [ion binding]; other site
1035817001393	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
1035817001394	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1035817001395	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1035817001396	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1035817001397	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1035817001398	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1035817001399	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1035817001400	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1035817001401	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1035817001402	putative active site [active]
1035817001403	substrate binding site [chemical binding]; other site
1035817001404	putative cosubstrate binding site; other site
1035817001405	catalytic site [active]
1035817001406	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1035817001407	substrate binding site [chemical binding]; other site
1035817001408	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1035817001409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817001410	primosome assembly protein PriA; Provisional; Region: PRK14873
1035817001411	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1035817001412	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817001413	motif II; other site
1035817001414	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1035817001415	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1035817001416	proteasome ATPase; Region: pup_AAA; TIGR03689
1035817001417	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001418	Walker A motif; other site
1035817001419	ATP binding site [chemical binding]; other site
1035817001420	Walker B motif; other site
1035817001421	arginine finger; other site
1035817001422	Pup-ligase protein; Region: Pup_ligase; cl15463
1035817001423	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1035817001424	active site
1035817001425	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1035817001426	Pup-like protein; Region: Pup; cl05289
1035817001427	Pup-ligase protein; Region: Pup_ligase; cl15463
1035817001428	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1035817001429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817001430	active site
1035817001431	phosphorylation site [posttranslational modification]
1035817001432	intermolecular recognition site; other site
1035817001433	dimerization interface [polypeptide binding]; other site
1035817001434	LytTr DNA-binding domain; Region: LytTR; smart00850
1035817001435	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1035817001436	similar to truncated glycoside hydrolase; BLNIAS_00686
1035817001437	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1035817001438	IHF dimer interface [polypeptide binding]; other site
1035817001439	IHF - DNA interface [nucleotide binding]; other site
1035817001440	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1035817001441	adenylosuccinate lyase; Provisional; Region: PRK09285
1035817001442	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1035817001443	tetramer interface [polypeptide binding]; other site
1035817001444	active site
1035817001445	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
1035817001446	PGAP1-like protein; Region: PGAP1; pfam07819
1035817001447	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1035817001448	metal ion-dependent adhesion site (MIDAS); other site
1035817001449	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1035817001450	Protein of unknown function DUF58; Region: DUF58; pfam01882
1035817001451	MoxR-like ATPases [General function prediction only]; Region: COG0714
1035817001452	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1035817001453	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1035817001454	ligand binding site [chemical binding]; other site
1035817001455	active site
1035817001456	UGI interface [polypeptide binding]; other site
1035817001457	catalytic site [active]
1035817001458	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
1035817001459	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1035817001460	DNA-binding site [nucleotide binding]; DNA binding site
1035817001461	RNA-binding motif; other site
1035817001462	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1035817001463	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1035817001464	ring oligomerisation interface [polypeptide binding]; other site
1035817001465	ATP/Mg binding site [chemical binding]; other site
1035817001466	stacking interactions; other site
1035817001467	hinge regions; other site
1035817001468	Proteins of 100 residues with WXG; Region: WXG100; pfam06013
1035817001469	Repair protein; Region: Repair_PSII; cl01535
1035817001470	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817001471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817001472	active site
1035817001473	phosphorylation site [posttranslational modification]
1035817001474	intermolecular recognition site; other site
1035817001475	dimerization interface [polypeptide binding]; other site
1035817001476	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1035817001477	DNA binding site [nucleotide binding]
1035817001478	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1035817001479	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1035817001480	dimerization interface [polypeptide binding]; other site
1035817001481	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1035817001482	dimer interface [polypeptide binding]; other site
1035817001483	phosphorylation site [posttranslational modification]
1035817001484	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817001485	ATP binding site [chemical binding]; other site
1035817001486	Mg2+ binding site [ion binding]; other site
1035817001487	G-X-G motif; other site
1035817001488	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1035817001489	DNA-binding site [nucleotide binding]; DNA binding site
1035817001490	RNA-binding motif; other site
1035817001491	Protein of unknown function (DUF3027); Region: DUF3027; pfam11228
1035817001492	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1035817001493	Ligand Binding Site [chemical binding]; other site
1035817001494	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1035817001495	Ligand Binding Site [chemical binding]; other site
1035817001496	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1035817001497	Clp amino terminal domain; Region: Clp_N; pfam02861
1035817001498	Clp amino terminal domain; Region: Clp_N; pfam02861
1035817001499	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001500	Walker A motif; other site
1035817001501	ATP binding site [chemical binding]; other site
1035817001502	Walker B motif; other site
1035817001503	arginine finger; other site
1035817001504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001505	Walker A motif; other site
1035817001506	ATP binding site [chemical binding]; other site
1035817001507	Walker B motif; other site
1035817001508	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1035817001509	cytosine deaminase; Provisional; Region: PRK09230
1035817001510	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1035817001511	active site
1035817001512	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1035817001513	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1035817001514	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001515	metabolite-proton symporter; Region: 2A0106; TIGR00883
1035817001516	putative substrate translocation pore; other site
1035817001517	Creatinine amidohydrolase; Region: Creatininase; pfam02633
1035817001518	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1035817001519	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1035817001520	active site
1035817001521	metal binding site [ion binding]; metal-binding site
1035817001522	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1035817001523	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1035817001524	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1035817001525	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1035817001526	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1035817001527	dimer interface [polypeptide binding]; other site
1035817001528	motif 1; other site
1035817001529	active site
1035817001530	motif 2; other site
1035817001531	motif 3; other site
1035817001532	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1035817001533	anticodon binding site; other site
1035817001534	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1035817001535	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1035817001536	dimer interface [polypeptide binding]; other site
1035817001537	anticodon binding site; other site
1035817001538	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1035817001539	motif 1; other site
1035817001540	dimer interface [polypeptide binding]; other site
1035817001541	active site
1035817001542	motif 2; other site
1035817001543	GAD domain; Region: GAD; pfam02938
1035817001544	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1035817001545	active site
1035817001546	motif 3; other site
1035817001547	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1035817001548	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1035817001549	Walker A/P-loop; other site
1035817001550	ATP binding site [chemical binding]; other site
1035817001551	Q-loop/lid; other site
1035817001552	ABC transporter signature motif; other site
1035817001553	Walker B; other site
1035817001554	D-loop; other site
1035817001555	H-loop/switch region; other site
1035817001556	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817001557	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1035817001558	substrate binding pocket [chemical binding]; other site
1035817001559	membrane-bound complex binding site; other site
1035817001560	hinge residues; other site
1035817001561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001562	dimer interface [polypeptide binding]; other site
1035817001563	conserved gate region; other site
1035817001564	ABC-ATPase subunit interface; other site
1035817001565	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1035817001566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001567	dimer interface [polypeptide binding]; other site
1035817001568	conserved gate region; other site
1035817001569	putative PBP binding loops; other site
1035817001570	ABC-ATPase subunit interface; other site
1035817001571	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1035817001572	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1035817001573	active site
1035817001574	Lamin Tail Domain; Region: LTD; pfam00932
1035817001575	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
1035817001576	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817001577	ATP binding site [chemical binding]; other site
1035817001578	putative Mg++ binding site [ion binding]; other site
1035817001579	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817001580	nucleotide binding region [chemical binding]; other site
1035817001581	ATP-binding site [chemical binding]; other site
1035817001582	Domain of unknown function (DUF3516); Region: DUF3516; pfam12029
1035817001583	recombination factor protein RarA; Reviewed; Region: PRK13342
1035817001584	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001585	Walker A motif; other site
1035817001586	ATP binding site [chemical binding]; other site
1035817001587	Walker B motif; other site
1035817001588	arginine finger; other site
1035817001589	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1035817001590	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817001591	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817001592	active site
1035817001593	phosphorylation site [posttranslational modification]
1035817001594	intermolecular recognition site; other site
1035817001595	dimerization interface [polypeptide binding]; other site
1035817001596	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1035817001597	DNA binding site [nucleotide binding]
1035817001598	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1035817001599	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1035817001600	dimerization interface [polypeptide binding]; other site
1035817001601	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1035817001602	dimer interface [polypeptide binding]; other site
1035817001603	phosphorylation site [posttranslational modification]
1035817001604	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817001605	ATP binding site [chemical binding]; other site
1035817001606	Mg2+ binding site [ion binding]; other site
1035817001607	G-X-G motif; other site
1035817001608	lipoprotein LpqB; Provisional; Region: PRK13613
1035817001609	Sporulation and spore germination; Region: Germane; pfam10646
1035817001610	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1035817001611	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1035817001612	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1035817001613	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1035817001614	Walker A/P-loop; other site
1035817001615	ATP binding site [chemical binding]; other site
1035817001616	Q-loop/lid; other site
1035817001617	ABC transporter signature motif; other site
1035817001618	Walker B; other site
1035817001619	D-loop; other site
1035817001620	H-loop/switch region; other site
1035817001621	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1035817001622	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1035817001623	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1035817001624	TM-ABC transporter signature motif; other site
1035817001625	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1035817001626	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1035817001627	TM-ABC transporter signature motif; other site
1035817001628	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001629	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1035817001630	putative substrate translocation pore; other site
1035817001631	Putative D-isomer specific 2-hydroxyacid dehydrogenase; Region: 2-Hacid_dh_1; cd05300
1035817001632	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1035817001633	NAD binding site [chemical binding]; other site
1035817001634	ligand binding site [chemical binding]; other site
1035817001635	catalytic site [active]
1035817001636	Membrane protein of unknown function; Region: DUF360; pfam04020
1035817001637	Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly; Region: CRS1_YhbY; smart01103
1035817001638	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817001639	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1035817001640	Walker A/P-loop; other site
1035817001641	ATP binding site [chemical binding]; other site
1035817001642	Q-loop/lid; other site
1035817001643	ABC transporter signature motif; other site
1035817001644	Walker B; other site
1035817001645	D-loop; other site
1035817001646	H-loop/switch region; other site
1035817001647	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817001648	Walker A/P-loop; other site
1035817001649	ATP binding site [chemical binding]; other site
1035817001650	Q-loop/lid; other site
1035817001651	ABC transporter signature motif; other site
1035817001652	Walker B; other site
1035817001653	D-loop; other site
1035817001654	H-loop/switch region; other site
1035817001655	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1035817001656	Predicted membrane protein [Function unknown]; Region: COG3601
1035817001657	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1035817001658	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1035817001659	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_b; cd04185
1035817001660	Probable Catalytic site; other site
1035817001661	Nitroreductase family; Region: Nitroreductase; pfam00881
1035817001662	FMN binding site [chemical binding]; other site
1035817001663	dimer interface [polypeptide binding]; other site
1035817001664	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817001665	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817001666	nucleotide binding site [chemical binding]; other site
1035817001667	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817001668	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1035817001669	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817001670	homodimer interface [polypeptide binding]; other site
1035817001671	catalytic residue [active]
1035817001672	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817001673	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1035817001674	Walker A/P-loop; other site
1035817001675	ATP binding site [chemical binding]; other site
1035817001676	ABC transporter signature motif; other site
1035817001677	Walker B; other site
1035817001678	D-loop; other site
1035817001679	H-loop/switch region; other site
1035817001680	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1035817001681	TPR repeat; Region: TPR_11; pfam13414
1035817001682	Ligase N family; Region: LIGANc; smart00532
1035817001683	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1035817001684	nucleotide binding pocket [chemical binding]; other site
1035817001685	K-X-D-G motif; other site
1035817001686	catalytic site [active]
1035817001687	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1035817001688	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1035817001689	Helix-hairpin-helix motif; Region: HHH; pfam00633
1035817001690	helix-hairpin-helix signature motif; other site
1035817001691	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1035817001692	Dimer interface [polypeptide binding]; other site
1035817001693	Domain of unknown function DUF59; Region: DUF59; cl00941
1035817001694	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1035817001695	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1035817001696	Walker A motif; other site
1035817001697	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817001698	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001699	dimer interface [polypeptide binding]; other site
1035817001700	conserved gate region; other site
1035817001701	putative PBP binding loops; other site
1035817001702	ABC-ATPase subunit interface; other site
1035817001703	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1035817001704	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1035817001705	Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA  is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine...; Region: GH20_GcnA-like; cd06565
1035817001706	putative active site [active]
1035817001707	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1035817001708	putative alpha-glucosidase; Provisional; Region: PRK10658
1035817001709	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1035817001710	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
1035817001711	active site
1035817001712	catalytic site [active]
1035817001713	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1035817001714	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1035817001715	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1035817001716	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
1035817001717	catalytic residues [active]
1035817001718	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1035817001719	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817001720	S-adenosylmethionine binding site [chemical binding]; other site
1035817001721	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1035817001722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1035817001723	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1035817001724	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817001725	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817001726	Walker A/P-loop; other site
1035817001727	ATP binding site [chemical binding]; other site
1035817001728	Q-loop/lid; other site
1035817001729	ABC transporter signature motif; other site
1035817001730	Walker B; other site
1035817001731	D-loop; other site
1035817001732	H-loop/switch region; other site
1035817001733	elongation factor P; Validated; Region: PRK00529
1035817001734	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1035817001735	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1035817001736	RNA binding site [nucleotide binding]; other site
1035817001737	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1035817001738	RNA binding site [nucleotide binding]; other site
1035817001739	transcription antitermination factor NusB; Region: nusB; TIGR01951
1035817001740	putative RNA binding site [nucleotide binding]; other site
1035817001741	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1035817001742	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1035817001743	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1035817001744	catalytic site [active]
1035817001745	subunit interface [polypeptide binding]; other site
1035817001746	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1035817001747	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1035817001748	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1035817001749	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1035817001750	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1035817001751	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1035817001752	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1035817001753	IMP binding site; other site
1035817001754	dimer interface [polypeptide binding]; other site
1035817001755	interdomain contacts; other site
1035817001756	partial ornithine binding site; other site
1035817001757	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1035817001758	active site
1035817001759	dimer interface [polypeptide binding]; other site
1035817001760	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1035817001761	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1035817001762	catalytic site [active]
1035817001763	G-X2-G-X-G-K; other site
1035817001764	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1035817001765	active site
1035817001766	catalytic site [active]
1035817001767	substrate binding site [chemical binding]; other site
1035817001768	Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168
1035817001769	elongation factor G; Reviewed; Region: PRK12740
1035817001770	G1 box; other site
1035817001771	putative GEF interaction site [polypeptide binding]; other site
1035817001772	GTP/Mg2+ binding site [chemical binding]; other site
1035817001773	Switch I region; other site
1035817001774	G2 box; other site
1035817001775	G3 box; other site
1035817001776	Switch II region; other site
1035817001777	G4 box; other site
1035817001778	G5 box; other site
1035817001779	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1035817001780	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
1035817001781	Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711
1035817001782	Predicted esterase [General function prediction only]; Region: COG0400
1035817001783	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
1035817001784	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1035817001785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001786	dimer interface [polypeptide binding]; other site
1035817001787	conserved gate region; other site
1035817001788	putative PBP binding loops; other site
1035817001789	ABC-ATPase subunit interface; other site
1035817001790	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1035817001791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001792	dimer interface [polypeptide binding]; other site
1035817001793	conserved gate region; other site
1035817001794	putative PBP binding loops; other site
1035817001795	ABC-ATPase subunit interface; other site
1035817001796	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1035817001797	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1035817001798	Walker A/P-loop; other site
1035817001799	ATP binding site [chemical binding]; other site
1035817001800	Q-loop/lid; other site
1035817001801	ABC transporter signature motif; other site
1035817001802	Walker B; other site
1035817001803	D-loop; other site
1035817001804	H-loop/switch region; other site
1035817001805	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1035817001806	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817001807	substrate binding pocket [chemical binding]; other site
1035817001808	membrane-bound complex binding site; other site
1035817001809	hinge residues; other site
1035817001810	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1035817001811	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1035817001812	homodimer interface [polypeptide binding]; other site
1035817001813	substrate-cofactor binding pocket; other site
1035817001814	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817001815	catalytic residue [active]
1035817001816	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1035817001817	catalytic residues [active]
1035817001818	Predicted transcriptional regulator [Transcription]; Region: COG1959
1035817001819	Zinc-binding dehydrogenase; Region: ADH_zinc_N_2; pfam13602
1035817001820	NIL domain; Region: NIL; pfam09383
1035817001821	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817001822	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1035817001823	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_4; cd03407
1035817001824	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1035817001825	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1035817001826	active site
1035817001827	nucleophile elbow; other site
1035817001828	glutamate racemase; Provisional; Region: PRK00865
1035817001829	Diaminopimelate epimerase [Amino acid transport and metabolism]; Region: DapF; COG0253
1035817001830	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1035817001831	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1035817001832	Vitamin K epoxide reductase family in bacteria; Region: VKOR_5; cd12922
1035817001833	putative active site [active]
1035817001834	redox center [active]
1035817001835	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1035817001836	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1035817001837	active site
1035817001838	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1035817001839	Protein of unknown function (DUF3107); Region: DUF3107; pfam11305
1035817001840	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1035817001841	substrate binding site [chemical binding]; other site
1035817001842	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1035817001843	Part of AAA domain; Region: AAA_19; pfam13245
1035817001844	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1035817001845	Family description; Region: UvrD_C_2; pfam13538
1035817001846	Uncharacterized conserved protein (DUF2342); Region: DUF2342; cl02183
1035817001847	Uncharacterized conserved protein (DUF2342); Region: DUF2342; cl02183
1035817001848	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1035817001849	Protein of unknown function (DUF3052); Region: DUF3052; pfam11253
1035817001850	DivIVA domain repeat protein; Region: divI1A_rptt_fam; TIGR03543
1035817001851	DivIVA domain; Region: DivI1A_domain; TIGR03544
1035817001852	DivIVA domain; Region: DivI1A_domain; TIGR03544
1035817001853	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1035817001854	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1035817001855	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1035817001856	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1035817001857	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1035817001858	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1035817001859	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1035817001860	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1035817001861	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1035817001862	Recombination protein O N terminal; Region: RecO_N; pfam11967
1035817001863	Recombination protein O C terminal; Region: RecO_C; pfam02565
1035817001864	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14829
1035817001865	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1035817001866	catalytic residue [active]
1035817001867	putative FPP diphosphate  binding site; other site
1035817001868	putative FPP binding hydrophobic cleft; other site
1035817001869	dimer interface [polypeptide binding]; other site
1035817001870	putative IPP diphosphate binding site; other site
1035817001871	nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.  This group contains eukaryotic, bacterial and archeal...; Region: nuc_hydro; cl00226
1035817001872	nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.  This group contains eukaryotic, bacterial and archeal...; Region: nuc_hydro; cl00226
1035817001873	active site
1035817001874	NMT1/THI5 like; Region: NMT1; pfam09084
1035817001875	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1035817001876	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817001877	dimer interface [polypeptide binding]; other site
1035817001878	conserved gate region; other site
1035817001879	putative PBP binding loops; other site
1035817001880	ABC-ATPase subunit interface; other site
1035817001881	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1035817001882	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1035817001883	substrate binding [chemical binding]; other site
1035817001884	active site
1035817001885	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1035817001886	galactoside permease; Reviewed; Region: lacY; PRK09528
1035817001887	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001888	putative substrate translocation pore; other site
1035817001889	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817001890	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817001891	DNA binding site [nucleotide binding]
1035817001892	domain linker motif; other site
1035817001893	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1035817001894	putative dimerization interface [polypeptide binding]; other site
1035817001895	putative ligand binding site [chemical binding]; other site
1035817001896	SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; Region: SERPIN; cd00172
1035817001897	serpin-like protein; Provisional; Region: PHA02660
1035817001898	reactive center loop; other site
1035817001899	benzoate transport; Region: 2A0115; TIGR00895
1035817001900	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001901	putative substrate translocation pore; other site
1035817001902	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817001903	putative substrate translocation pore; other site
1035817001904	Domain of unknown function DUF77; Region: DUF77; pfam01910
1035817001905	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1035817001906	substrate binding site [chemical binding]; other site
1035817001907	dimer interface [polypeptide binding]; other site
1035817001908	ATP binding site [chemical binding]; other site
1035817001909	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1035817001910	thiamine phosphate binding site [chemical binding]; other site
1035817001911	active site
1035817001912	pyrophosphate binding site [ion binding]; other site
1035817001913	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1035817001914	ThiC-associated domain; Region: ThiC-associated; pfam13667
1035817001915	ThiC family; Region: ThiC; pfam01964
1035817001916	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1035817001917	substrate binding site [chemical binding]; other site
1035817001918	multimerization interface [polypeptide binding]; other site
1035817001919	ATP binding site [chemical binding]; other site
1035817001920	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1035817001921	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1035817001922	motif 1; other site
1035817001923	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1035817001924	active site
1035817001925	motif 2; other site
1035817001926	motif 3; other site
1035817001927	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
1035817001928	anticodon binding site; other site
1035817001929	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1035817001930	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1035817001931	FMN binding site [chemical binding]; other site
1035817001932	active site
1035817001933	catalytic residues [active]
1035817001934	substrate binding site [chemical binding]; other site
1035817001935	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
1035817001936	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1035817001937	nucleotide binding site [chemical binding]; other site
1035817001938	SulA interaction site; other site
1035817001939	Protein of unknown function (DUF552); Region: DUF552; pfam04472
1035817001940	YGGT family; Region: YGGT; pfam02325
1035817001941	DivIVA protein; Region: DivIVA; pfam05103
1035817001942	DivIVA domain; Region: DivI1A_domain; TIGR03544
1035817001943	lipoprotein signal peptidase; Provisional; Region: PRK14771
1035817001944	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1035817001945	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1035817001946	active site
1035817001947	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1035817001948	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1035817001949	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1035817001950	Predicted transcriptional regulator [Transcription]; Region: COG2378
1035817001951	putative DNA binding site [nucleotide binding]; other site
1035817001952	putative Zn2+ binding site [ion binding]; other site
1035817001953	WYL domain; Region: WYL; pfam13280
1035817001954	potential frameshift: common BLAST hit: gi|322691507|ref|YP_004221077.1| DNA polymerase III alpha subunit
1035817001955	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1035817001956	PHP domain; Region: PHP; pfam02811
1035817001957	active site
1035817001958	PHP Thumb interface [polypeptide binding]; other site
1035817001959	metal binding site [ion binding]; metal-binding site
1035817001960	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
1035817001961	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1035817001962	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1035817001963	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1035817001964	Family description; Region: UvrD_C_2; pfam13538
1035817001965	Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; Region: Tubulin_FtsZ; cl10017
1035817001966	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1035817001967	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817001968	Integrase core domain; Region: rve; pfam00665
1035817001969	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1035817001970	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817001971	Walker A motif; other site
1035817001972	ATP binding site [chemical binding]; other site
1035817001973	Walker B motif; other site
1035817001974	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1035817001975	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817001976	DNA-binding interface [nucleotide binding]; DNA binding site
1035817001977	Integrase core domain; Region: rve; pfam00665
1035817001978	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1035817001979	Walker A motif; other site
1035817001980	ATP binding site [chemical binding]; other site
1035817001981	similar to truncated transposase; BLNIAS_00924
1035817001982	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817001983	active site
1035817001984	DNA binding site [nucleotide binding]
1035817001985	Int/Topo IB signature motif; other site
1035817001986	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1035817001987	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817001988	active site
1035817001989	DNA binding site [nucleotide binding]
1035817001990	Int/Topo IB signature motif; other site
1035817001991	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1035817001992	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817001993	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
1035817001994	Int/Topo IB signature motif; other site
1035817001995	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1035817001996	HTH-like domain; Region: HTH_21; pfam13276
1035817001997	Integrase core domain; Region: rve; pfam00665
1035817001998	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817001999	Integrase core domain; Region: rve; pfam00665
1035817002000	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1035817002001	Protein of unknown function DUF262; Region: DUF262; pfam03235
1035817002002	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1035817002003	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1035817002004	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1035817002005	active site
1035817002006	PHP Thumb interface [polypeptide binding]; other site
1035817002007	metal binding site [ion binding]; metal-binding site
1035817002008	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1035817002009	generic binding surface II; other site
1035817002010	generic binding surface I; other site
1035817002011	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1035817002012	myosin-cross-reactive antigen; Provisional; Region: PRK13977
1035817002013	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1035817002014	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817002015	Coenzyme A binding pocket [chemical binding]; other site
1035817002016	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817002017	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817002018	active site
1035817002019	catalytic tetrad [active]
1035817002020	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1035817002021	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817002022	nucleotide binding site [chemical binding]; other site
1035817002023	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1035817002024	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1035817002025	NAD binding site [chemical binding]; other site
1035817002026	dimerization interface [polypeptide binding]; other site
1035817002027	product binding site; other site
1035817002028	substrate binding site [chemical binding]; other site
1035817002029	zinc binding site [ion binding]; other site
1035817002030	catalytic residues [active]
1035817002031	histidinol-phosphate aminotransferase; Provisional; Region: PRK03317
1035817002032	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817002033	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817002034	homodimer interface [polypeptide binding]; other site
1035817002035	catalytic residue [active]
1035817002036	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1035817002037	putative active site pocket [active]
1035817002038	4-fold oligomerization interface [polypeptide binding]; other site
1035817002039	metal binding residues [ion binding]; metal-binding site
1035817002040	3-fold/trimer interface [polypeptide binding]; other site
1035817002041	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
1035817002042	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1035817002043	putative active site [active]
1035817002044	oxyanion strand; other site
1035817002045	catalytic triad [active]
1035817002046	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1035817002047	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1035817002048	catalytic residues [active]
1035817002049	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1035817002050	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
1035817002051	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1035817002052	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1035817002053	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1035817002054	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1035817002055	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1035817002056	ATP-dependent helicase HrpA; Region: DEAH_box_HrpA; TIGR01967
1035817002057	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817002058	ATP binding site [chemical binding]; other site
1035817002059	putative Mg++ binding site [ion binding]; other site
1035817002060	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817002061	nucleotide binding region [chemical binding]; other site
1035817002062	ATP-binding site [chemical binding]; other site
1035817002063	Helicase associated domain (HA2); Region: HA2; pfam04408
1035817002064	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1035817002065	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1035817002066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817002067	S-adenosylmethionine binding site [chemical binding]; other site
1035817002068	GTPases [General function prediction only]; Region: HflX; COG2262
1035817002069	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1035817002070	HflX GTPase family; Region: HflX; cd01878
1035817002071	G1 box; other site
1035817002072	GTP/Mg2+ binding site [chemical binding]; other site
1035817002073	Switch I region; other site
1035817002074	G2 box; other site
1035817002075	G3 box; other site
1035817002076	Switch II region; other site
1035817002077	G4 box; other site
1035817002078	G5 box; other site
1035817002079	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
1035817002080	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1035817002081	NAD binding site [chemical binding]; other site
1035817002082	dimer interface [polypeptide binding]; other site
1035817002083	substrate binding site [chemical binding]; other site
1035817002084	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1035817002085	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1035817002086	LexA repressor; Validated; Region: PRK00215
1035817002087	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1035817002088	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1035817002089	Catalytic site [active]
1035817002090	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1035817002091	ATP cone domain; Region: ATP-cone; pfam03477
1035817002092	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1035817002093	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1035817002094	ligand binding site [chemical binding]; other site
1035817002095	NAD binding site [chemical binding]; other site
1035817002096	tetramer interface [polypeptide binding]; other site
1035817002097	catalytic site [active]
1035817002098	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1035817002099	L-serine binding site [chemical binding]; other site
1035817002100	ACT domain interface; other site
1035817002101	Part of AAA domain; Region: AAA_19; pfam13245
1035817002102	Family description; Region: UvrD_C_2; pfam13538
1035817002103	cell division protein MraZ; Reviewed; Region: PRK00326
1035817002104	MraZ protein; Region: MraZ; pfam02381
1035817002105	MraZ protein; Region: MraZ; pfam02381
1035817002106	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1035817002107	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817002108	S-adenosylmethionine binding site [chemical binding]; other site
1035817002109	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1035817002110	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1035817002111	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1035817002112	putative bifunctional UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase/UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase; Provisional; Region: PRK11929
1035817002113	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1035817002114	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1035817002115	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817002116	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1035817002117	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1035817002118	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1035817002119	Mg++ binding site [ion binding]; other site
1035817002120	putative catalytic motif [active]
1035817002121	putative substrate binding site [chemical binding]; other site
1035817002122	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1035817002123	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01438
1035817002124	NAD binding site [chemical binding]; other site
1035817002125	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817002126	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1035817002127	cell division protein FtsW; Region: ftsW; TIGR02614
1035817002128	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1035817002129	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1035817002130	active site
1035817002131	homodimer interface [polypeptide binding]; other site
1035817002132	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1035817002133	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1035817002134	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817002135	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1035817002136	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1035817002137	Cell division protein FtsQ; Region: FtsQ; pfam03799
1035817002138	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1035817002139	putative ADP-ribose binding site [chemical binding]; other site
1035817002140	putative active site [active]
1035817002141	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1035817002142	metal ion-dependent adhesion site (MIDAS); other site
1035817002143	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1035817002144	putative active site [active]
1035817002145	dimerization interface [polypeptide binding]; other site
1035817002146	putative tRNAtyr binding site [nucleotide binding]; other site
1035817002147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817002148	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1035817002149	putative substrate translocation pore; other site
1035817002150	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1035817002151	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1035817002152	active site
1035817002153	metal binding site [ion binding]; metal-binding site
1035817002154	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1035817002155	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1035817002156	putative substrate binding site [chemical binding]; other site
1035817002157	putative ATP binding site [chemical binding]; other site
1035817002158	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1035817002159	putative DNA binding site [nucleotide binding]; other site
1035817002160	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1035817002161	putative Zn2+ binding site [ion binding]; other site
1035817002162	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817002163	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817002164	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817002165	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817002166	nucleotide binding site [chemical binding]; other site
1035817002167	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1035817002168	non-specific DNA interactions [nucleotide binding]; other site
1035817002169	DNA binding site [nucleotide binding]
1035817002170	sequence specific DNA binding site [nucleotide binding]; other site
1035817002171	putative cAMP binding site [chemical binding]; other site
1035817002172	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817002173	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1035817002174	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1035817002175	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1035817002176	active site
1035817002177	trimer interface [polypeptide binding]; other site
1035817002178	allosteric site; other site
1035817002179	active site lid [active]
1035817002180	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1035817002181	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1035817002182	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1035817002183	active site
1035817002184	dimer interface [polypeptide binding]; other site
1035817002185	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1035817002186	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_20; cd08519
1035817002187	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1035817002188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817002189	dimer interface [polypeptide binding]; other site
1035817002190	conserved gate region; other site
1035817002191	putative PBP binding loops; other site
1035817002192	ABC-ATPase subunit interface; other site
1035817002193	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1035817002194	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817002195	dimer interface [polypeptide binding]; other site
1035817002196	conserved gate region; other site
1035817002197	ABC-ATPase subunit interface; other site
1035817002198	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1035817002199	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817002200	Walker A/P-loop; other site
1035817002201	ATP binding site [chemical binding]; other site
1035817002202	Q-loop/lid; other site
1035817002203	ABC transporter signature motif; other site
1035817002204	Walker B; other site
1035817002205	D-loop; other site
1035817002206	H-loop/switch region; other site
1035817002207	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1035817002208	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817002209	Walker A/P-loop; other site
1035817002210	ATP binding site [chemical binding]; other site
1035817002211	Q-loop/lid; other site
1035817002212	ABC transporter signature motif; other site
1035817002213	Walker B; other site
1035817002214	D-loop; other site
1035817002215	H-loop/switch region; other site
1035817002216	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1035817002217	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_17; cd04676
1035817002218	nudix motif; other site
1035817002219	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
1035817002220	proline aminopeptidase P II; Provisional; Region: PRK10879
1035817002221	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1035817002222	active site
1035817002223	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1035817002224	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817002225	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1035817002226	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1035817002227	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1035817002228	Walker A/P-loop; other site
1035817002229	ATP binding site [chemical binding]; other site
1035817002230	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
1035817002231	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1035817002232	ABC transporter signature motif; other site
1035817002233	Walker B; other site
1035817002234	D-loop; other site
1035817002235	H-loop/switch region; other site
1035817002236	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1035817002237	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1035817002238	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1035817002239	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817002240	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1035817002241	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1035817002242	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1035817002243	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1035817002244	DNA binding residues [nucleotide binding]
1035817002245	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1035817002246	active site
1035817002247	catalytic residues [active]
1035817002248	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1035817002249	active site
1035817002250	catalytic residues [active]
1035817002251	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1035817002252	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1035817002253	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1035817002254	putative deacylase active site [active]
1035817002255	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1035817002256	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1035817002257	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1035817002258	Thiamine pyrophosphokinase; Region: TPK; cd07995
1035817002259	active site
1035817002260	dimerization interface [polypeptide binding]; other site
1035817002261	thiamine binding site [chemical binding]; other site
1035817002262	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817002263	S-adenosylmethionine binding site [chemical binding]; other site
1035817002264	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1035817002265	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1035817002266	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1035817002267	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1035817002268	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1035817002269	23S rRNA binding site [nucleotide binding]; other site
1035817002270	L21 binding site [polypeptide binding]; other site
1035817002271	L13 binding site [polypeptide binding]; other site
1035817002272	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1035817002273	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1035817002274	active site
1035817002275	Int/Topo IB signature motif; other site
1035817002276	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817002277	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817002278	Walker A/P-loop; other site
1035817002279	ATP binding site [chemical binding]; other site
1035817002280	Q-loop/lid; other site
1035817002281	ABC transporter signature motif; other site
1035817002282	Walker B; other site
1035817002283	D-loop; other site
1035817002284	H-loop/switch region; other site
1035817002285	FtsX-like permease family; Region: FtsX; pfam02687
1035817002286	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1035817002287	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817002288	P-loop; other site
1035817002289	Magnesium ion binding site [ion binding]; other site
1035817002290	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817002291	Magnesium ion binding site [ion binding]; other site
1035817002292	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
1035817002293	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
1035817002294	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
1035817002295	nudix motif; other site
1035817002296	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1035817002297	quinolinate synthetase; Provisional; Region: PRK09375
1035817002298	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1035817002299	L-aspartate oxidase; Provisional; Region: PRK06175
1035817002300	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1035817002301	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06543
1035817002302	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1035817002303	dimerization interface [polypeptide binding]; other site
1035817002304	active site
1035817002305	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1035817002306	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1035817002307	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1035817002308	catalytic residue [active]
1035817002309	benzoate transport; Region: 2A0115; TIGR00895
1035817002310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817002311	putative substrate translocation pore; other site
1035817002312	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1035817002313	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1035817002314	G1 box; other site
1035817002315	putative GEF interaction site [polypeptide binding]; other site
1035817002316	GTP/Mg2+ binding site [chemical binding]; other site
1035817002317	Switch I region; other site
1035817002318	G2 box; other site
1035817002319	G3 box; other site
1035817002320	Switch II region; other site
1035817002321	G4 box; other site
1035817002322	G5 box; other site
1035817002323	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1035817002324	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1035817002325	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1035817002326	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1035817002327	Prephenate dehydratase; Region: PDT; pfam00800
1035817002328	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1035817002329	putative L-Phe binding site [chemical binding]; other site
1035817002330	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1035817002331	prephenate dehydrogenase; Validated; Region: PRK08507
1035817002332	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1035817002333	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002334	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002335	active site
1035817002336	DNA binding site [nucleotide binding]
1035817002337	Int/Topo IB signature motif; other site
1035817002338	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1035817002339	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1035817002340	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1035817002341	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817002342	dimer interface [polypeptide binding]; other site
1035817002343	conserved gate region; other site
1035817002344	putative PBP binding loops; other site
1035817002345	ABC-ATPase subunit interface; other site
1035817002346	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1035817002347	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817002348	dimer interface [polypeptide binding]; other site
1035817002349	conserved gate region; other site
1035817002350	putative PBP binding loops; other site
1035817002351	ABC-ATPase subunit interface; other site
1035817002352	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817002353	AAA domain; Region: AAA_21; pfam13304
1035817002354	Walker A/P-loop; other site
1035817002355	ATP binding site [chemical binding]; other site
1035817002356	Q-loop/lid; other site
1035817002357	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817002358	ABC transporter signature motif; other site
1035817002359	Walker B; other site
1035817002360	D-loop; other site
1035817002361	H-loop/switch region; other site
1035817002362	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1035817002363	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817002364	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1035817002365	Walker A/P-loop; other site
1035817002366	ATP binding site [chemical binding]; other site
1035817002367	Q-loop/lid; other site
1035817002368	ABC transporter signature motif; other site
1035817002369	Walker B; other site
1035817002370	D-loop; other site
1035817002371	H-loop/switch region; other site
1035817002372	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1035817002373	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
1035817002374	putative active site [active]
1035817002375	putative catalytic site [active]
1035817002376	putative DNA binding site [nucleotide binding]; other site
1035817002377	putative phosphate binding site [ion binding]; other site
1035817002378	metal binding site A [ion binding]; metal-binding site
1035817002379	putative AP binding site [nucleotide binding]; other site
1035817002380	putative metal binding site B [ion binding]; other site
1035817002381	Protein of unknown function (DUF3710); Region: DUF3710; pfam12502
1035817002382	Protein of unknown function (DUF3159); Region: DUF3159; pfam11361
1035817002383	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1035817002384	TRAM domain; Region: TRAM; cl01282
1035817002385	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817002386	S-adenosylmethionine binding site [chemical binding]; other site
1035817002387	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1035817002388	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
1035817002389	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1035817002390	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1035817002391	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817002392	motif II; other site
1035817002393	aconitate hydratase; Validated; Region: PRK09277
1035817002394	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1035817002395	substrate binding site [chemical binding]; other site
1035817002396	ligand binding site [chemical binding]; other site
1035817002397	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1035817002398	substrate binding site [chemical binding]; other site
1035817002399	RelB antitoxin; Region: RelB; cl01171
1035817002400	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG1848
1035817002401	putative active site [active]
1035817002402	Protein of unknown function DUF262; Region: DUF262; pfam03235
1035817002403	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1035817002404	Protein of unknown function DUF262; Region: DUF262; pfam03235
1035817002405	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1035817002406	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817002407	Coenzyme A binding pocket [chemical binding]; other site
1035817002408	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817002409	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817002410	active site
1035817002411	phosphorylation site [posttranslational modification]
1035817002412	intermolecular recognition site; other site
1035817002413	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1035817002414	DNA binding residues [nucleotide binding]
1035817002415	dimerization interface [polypeptide binding]; other site
1035817002416	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1035817002417	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1035817002418	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1035817002419	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1035817002420	EamA-like transporter family; Region: EamA; pfam00892
1035817002421	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1035817002422	synthetase active site [active]
1035817002423	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1035817002424	NTP binding site [chemical binding]; other site
1035817002425	metal binding site [ion binding]; metal-binding site
1035817002426	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14326
1035817002427	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1035817002428	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1035817002429	FeS/SAM binding site; other site
1035817002430	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1035817002431	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1035817002432	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1035817002433	Fic/DOC family; Region: Fic; cl00960
1035817002434	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1035817002435	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1035817002436	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1035817002437	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1035817002438	Competence-damaged protein; Region: CinA; pfam02464
1035817002439	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817002440	sequence-specific DNA binding site [nucleotide binding]; other site
1035817002441	salt bridge; other site
1035817002442	Protein of unknown function (DUF3046); Region: DUF3046; pfam11248
1035817002443	recombinase A; Provisional; Region: recA; PRK09354
1035817002444	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1035817002445	hexamer interface [polypeptide binding]; other site
1035817002446	Walker A motif; other site
1035817002447	ATP binding site [chemical binding]; other site
1035817002448	Walker B motif; other site
1035817002449	RecX family; Region: RecX; pfam02631
1035817002450	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1035817002451	30S subunit binding site; other site
1035817002452	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1035817002453	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1035817002454	ATP binding site [chemical binding]; other site
1035817002455	putative Mg++ binding site [ion binding]; other site
1035817002456	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1035817002457	SEC-C motif; Region: SEC-C; pfam02810
1035817002458	similar to truncated transposase; BLNIAS_01139
1035817002459	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1035817002460	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1035817002461	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1035817002462	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1035817002463	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1035817002464	putative acyl-acceptor binding pocket; other site
1035817002465	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817002466	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1035817002467	active site
1035817002468	ATP binding site [chemical binding]; other site
1035817002469	substrate binding site [chemical binding]; other site
1035817002470	activation loop (A-loop); other site
1035817002471	PASTA domain; Region: PASTA; pfam03793
1035817002472	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817002473	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817002474	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1035817002475	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1035817002476	substrate binding pocket [chemical binding]; other site
1035817002477	chain length determination region; other site
1035817002478	substrate-Mg2+ binding site; other site
1035817002479	catalytic residues [active]
1035817002480	aspartate-rich region 1; other site
1035817002481	active site lid residues [active]
1035817002482	aspartate-rich region 2; other site
1035817002483	RNA polymerase sigma factor SigB; Reviewed; Region: PRK07921
1035817002484	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1035817002485	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1035817002486	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1035817002487	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1035817002488	DNA binding residues [nucleotide binding]
1035817002489	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817002490	Mg2+ binding site [ion binding]; other site
1035817002491	G-X-G motif; other site
1035817002492	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1035817002493	anchoring element; other site
1035817002494	dimer interface [polypeptide binding]; other site
1035817002495	ATP binding site [chemical binding]; other site
1035817002496	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1035817002497	active site
1035817002498	metal binding site [ion binding]; metal-binding site
1035817002499	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1035817002500	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817002501	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817002502	putative substrate translocation pore; other site
1035817002503	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1035817002504	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1035817002505	substrate binding site [chemical binding]; other site
1035817002506	dimer interface [polypeptide binding]; other site
1035817002507	ATP binding site [chemical binding]; other site
1035817002508	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1035817002509	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817002510	ATP binding site [chemical binding]; other site
1035817002511	putative Mg++ binding site [ion binding]; other site
1035817002512	Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201
1035817002513	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817002514	nucleotide binding region [chemical binding]; other site
1035817002515	ATP-binding site [chemical binding]; other site
1035817002516	DEAD/H associated; Region: DEAD_assoc; pfam08494
1035817002517	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817002518	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1035817002519	phosphorylation site [posttranslational modification]
1035817002520	intermolecular recognition site; other site
1035817002521	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
1035817002522	DNA binding site [nucleotide binding]
1035817002523	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1035817002524	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1035817002525	CAP-like domain; other site
1035817002526	active site
1035817002527	primary dimer interface [polypeptide binding]; other site
1035817002528	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817002529	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1035817002530	Protein of unknown function (DUF3071); Region: DUF3071; pfam11268
1035817002531	Domain of unknown function (DUF4193); Region: DUF4193; pfam13834
1035817002532	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1035817002533	trimer interface [polypeptide binding]; other site
1035817002534	active site
1035817002535	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1035817002536	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1035817002537	Zn2+ binding site [ion binding]; other site
1035817002538	Mg2+ binding site [ion binding]; other site
1035817002539	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1035817002540	synthetase active site [active]
1035817002541	NTP binding site [chemical binding]; other site
1035817002542	metal binding site [ion binding]; metal-binding site
1035817002543	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1035817002544	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1035817002545	Integrase core domain; Region: rve; pfam00665
1035817002546	Integrase core domain; Region: rve_2; pfam13333
1035817002547	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1035817002548	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002549	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
1035817002550	Int/Topo IB signature motif; other site
1035817002551	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002552	active site
1035817002553	DNA binding site [nucleotide binding]
1035817002554	Int/Topo IB signature motif; other site
1035817002555	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002556	active site
1035817002557	Int/Topo IB signature motif; other site
1035817002558	DNA binding site [nucleotide binding]
1035817002559	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817002560	MULE transposase domain; Region: MULE; pfam10551
1035817002561	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002562	Integrase core domain; Region: rve; pfam00665
1035817002563	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1035817002564	active site
1035817002565	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817002566	Integrase core domain; Region: rve; pfam00665
1035817002567	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817002568	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1035817002569	Walker A motif; other site
1035817002570	ATP binding site [chemical binding]; other site
1035817002571	Walker B motif; other site
1035817002572	arginine finger; other site
1035817002573	RelB antitoxin; Region: RelB; cl01171
1035817002574	PemK-like protein; Region: PemK; pfam02452
1035817002575	Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; Region: Tubulin_FtsZ; cl10017
1035817002576	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_1; cd10446
1035817002577	GIY-YIG motif/motif A; other site
1035817002578	putative active site [active]
1035817002579	putative metal binding site [ion binding]; other site
1035817002580	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
1035817002581	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1035817002582	EamA-like transporter family; Region: EamA; pfam00892
1035817002583	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1035817002584	EamA-like transporter family; Region: EamA; pfam00892
1035817002585	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1035817002586	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1035817002587	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817002588	catalytic core [active]
1035817002589	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1035817002590	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1035817002591	Cl binding site [ion binding]; other site
1035817002592	oligomer interface [polypeptide binding]; other site
1035817002593	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1035817002594	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817002595	substrate binding pocket [chemical binding]; other site
1035817002596	membrane-bound complex binding site; other site
1035817002597	hinge residues; other site
1035817002598	Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: LeuS; COG0495
1035817002599	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817002600	active site
1035817002601	HIGH motif; other site
1035817002602	nucleotide binding site [chemical binding]; other site
1035817002603	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817002604	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1035817002605	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817002606	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817002607	active site
1035817002608	KMSKS motif; other site
1035817002609	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1035817002610	tRNA binding surface [nucleotide binding]; other site
1035817002611	Helix-hairpin-helix motif; Region: HHH; pfam00633
1035817002612	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1035817002613	Competence protein; Region: Competence; pfam03772
1035817002614	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1035817002615	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1035817002616	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1035817002617	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
1035817002618	active site
1035817002619	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
1035817002620	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1035817002621	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1035817002622	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1035817002623	Glycoprotease family; Region: Peptidase_M22; pfam00814
1035817002624	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1035817002625	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817002626	Coenzyme A binding pocket [chemical binding]; other site
1035817002627	UGMP family protein; Validated; Region: PRK09604
1035817002628	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1035817002629	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1035817002630	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002631	active site
1035817002632	DNA binding site [nucleotide binding]
1035817002633	Int/Topo IB signature motif; other site
1035817002634	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1035817002635	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817002636	Fic/DOC family; Region: Fic; pfam02661
1035817002637	Antirestriction protein (ArdA); Region: ArdA; cl01953
1035817002638	CHAP domain; Region: CHAP; pfam05257
1035817002639	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1035817002640	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1035817002641	catalytic residue [active]
1035817002642	DNA topoisomerase III; Provisional; Region: PRK07726
1035817002643	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1035817002644	active site
1035817002645	putative interdomain interaction site [polypeptide binding]; other site
1035817002646	putative metal-binding site [ion binding]; other site
1035817002647	putative nucleotide binding site [chemical binding]; other site
1035817002648	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
1035817002649	domain I; other site
1035817002650	DNA binding groove [nucleotide binding]
1035817002651	phosphate binding site [ion binding]; other site
1035817002652	domain II; other site
1035817002653	domain III; other site
1035817002654	nucleotide binding site [chemical binding]; other site
1035817002655	catalytic site [active]
1035817002656	domain IV; other site
1035817002657	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1035817002658	Ribbon-helix-helix domain; Region: RHH_3; pfam12651
1035817002659	EcoRII C terminal; Region: EcoRII-C; pfam09019
1035817002660	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1035817002661	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1035817002662	cofactor binding site; other site
1035817002663	DNA binding site [nucleotide binding]
1035817002664	substrate interaction site [chemical binding]; other site
1035817002665	Fic family protein [Function unknown]; Region: COG3177
1035817002666	Fic/DOC family; Region: Fic; pfam02661
1035817002667	HipA N-terminal domain; Region: Couple_hipA; cl11853
1035817002668	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1035817002669	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1035817002670	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
1035817002671	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
1035817002672	AAA-like domain; Region: AAA_10; pfam12846
1035817002673	Archaeal/vacuolar-type H+-ATPase subunit I [Energy production and conversion]; Region: NtpI; COG1269
1035817002674	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1035817002675	T surface-antigen of pili; Region: FctA; pfam12892
1035817002676	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002677	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002678	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002679	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002680	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002681	T surface-antigen of pili; Region: FctA; pfam12892
1035817002682	T surface-antigen of pili; Region: FctA; pfam12892
1035817002683	streptococcal pilin isopeptide linkage domain; Region: strep_pil_rpt; TIGR03786
1035817002684	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
1035817002685	adhesin isopeptide-forming domain, sspB-C2 type; Region: isopep_sspB_C2; TIGR04228
1035817002686	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1035817002687	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817002688	P-loop; other site
1035817002689	Magnesium ion binding site [ion binding]; other site
1035817002690	Transcription factor WhiB; Region: Whib; pfam02467
1035817002691	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1035817002692	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817002693	non-specific DNA binding site [nucleotide binding]; other site
1035817002694	salt bridge; other site
1035817002695	sequence-specific DNA binding site [nucleotide binding]; other site
1035817002696	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1035817002697	Peptidase family M23; Region: Peptidase_M23; pfam01551
1035817002698	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1035817002699	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1035817002700	isocitrate dehydrogenase; Validated; Region: PRK08299
1035817002701	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK08649
1035817002702	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1035817002703	active site
1035817002704	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1035817002705	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1035817002706	acyl-activating enzyme (AAE) consensus motif; other site
1035817002707	putative AMP binding site [chemical binding]; other site
1035817002708	putative active site [active]
1035817002709	putative CoA binding site [chemical binding]; other site
1035817002710	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1035817002711	active site
1035817002712	catalytic residues [active]
1035817002713	metal binding site [ion binding]; metal-binding site
1035817002714	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1035817002715	rRNA interaction site [nucleotide binding]; other site
1035817002716	S8 interaction site; other site
1035817002717	putative laminin-1 binding site; other site
1035817002718	elongation factor Ts; Provisional; Region: tsf; PRK09377
1035817002719	Elongation factor TS; Region: EF_TS; pfam00889
1035817002720	Elongation factor TS; Region: EF_TS; pfam00889
1035817002721	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1035817002722	putative nucleotide binding site [chemical binding]; other site
1035817002723	uridine monophosphate binding site [chemical binding]; other site
1035817002724	homohexameric interface [polypeptide binding]; other site
1035817002725	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1035817002726	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1035817002727	hinge region; other site
1035817002728	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1035817002729	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1035817002730	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14459
1035817002731	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1035817002732	FeS/SAM binding site; other site
1035817002733	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1035817002734	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1035817002735	proposed catalytic triad [active]
1035817002736	conserved cys residue [active]
1035817002737	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1035817002738	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1035817002739	substrate binding site [chemical binding]; other site
1035817002740	glutamase interaction surface [polypeptide binding]; other site
1035817002741	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1035817002742	anthranilate synthase component I; Provisional; Region: PRK13571
1035817002743	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1035817002744	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1035817002745	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cl00237
1035817002746	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1035817002747	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817002748	Walker A/P-loop; other site
1035817002749	ATP binding site [chemical binding]; other site
1035817002750	Q-loop/lid; other site
1035817002751	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1035817002752	ABC transporter signature motif; other site
1035817002753	Walker B; other site
1035817002754	D-loop; other site
1035817002755	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1035817002756	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1035817002757	classical (c) SDRs; Region: SDR_c; cd05233
1035817002758	NAD(P) binding site [chemical binding]; other site
1035817002759	active site
1035817002760	Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein; Region: MMP_ACEL2062; cd12952
1035817002761	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1035817002762	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817002763	Walker A/P-loop; other site
1035817002764	ATP binding site [chemical binding]; other site
1035817002765	Q-loop/lid; other site
1035817002766	ABC transporter signature motif; other site
1035817002767	Walker B; other site
1035817002768	D-loop; other site
1035817002769	H-loop/switch region; other site
1035817002770	Second domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain2; cd03226
1035817002771	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817002772	Walker A/P-loop; other site
1035817002773	ATP binding site [chemical binding]; other site
1035817002774	Q-loop/lid; other site
1035817002775	ABC transporter signature motif; other site
1035817002776	Walker B; other site
1035817002777	D-loop; other site
1035817002778	H-loop/switch region; other site
1035817002779	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1035817002780	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; pfam09605
1035817002781	Protein of unknown function (DUF3375); Region: DUF3375; pfam11855
1035817002782	Domain of unknown function (DUF4194); Region: DUF4194; pfam13835
1035817002783	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4913
1035817002784	P-loop containing region of AAA domain; Region: AAA_29; pfam13555
1035817002785	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1035817002786	Uncharacterized protein conserved in bacteria N-term (DUF3322); Region: DUF3322; pfam11795
1035817002787	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4924
1035817002788	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
1035817002789	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1035817002790	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1035817002791	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1035817002792	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1035817002793	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1035817002794	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1035817002795	GIY-YIG motif/motif A; other site
1035817002796	active site
1035817002797	catalytic site [active]
1035817002798	putative DNA binding site [nucleotide binding]; other site
1035817002799	metal binding site [ion binding]; metal-binding site
1035817002800	UvrB/uvrC motif; Region: UVR; pfam02151
1035817002801	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1035817002802	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1035817002803	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1035817002804	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1035817002805	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1035817002806	shikimate binding site; other site
1035817002807	NAD(P) binding site [chemical binding]; other site
1035817002808	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1035817002809	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1035817002810	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
1035817002811	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1035817002812	Phosphoglycerate kinase; Region: PGK; pfam00162
1035817002813	substrate binding site [chemical binding]; other site
1035817002814	hinge regions; other site
1035817002815	ADP binding site [chemical binding]; other site
1035817002816	catalytic site [active]
1035817002817	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1035817002818	triosephosphate isomerase; Provisional; Region: PRK14567
1035817002819	substrate binding site [chemical binding]; other site
1035817002820	dimer interface [polypeptide binding]; other site
1035817002821	catalytic triad [active]
1035817002822	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1035817002823	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1035817002824	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1035817002825	NAD binding site [chemical binding]; other site
1035817002826	dimer interface [polypeptide binding]; other site
1035817002827	substrate binding site [chemical binding]; other site
1035817002828	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1035817002829	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817002830	active site
1035817002831	motif I; other site
1035817002832	motif II; other site
1035817002833	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1035817002834	bifunctional HTH-domain containing protein/aminotransferase; Provisional; Region: PRK13355
1035817002835	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817002836	non-specific DNA binding site [nucleotide binding]; other site
1035817002837	salt bridge; other site
1035817002838	sequence-specific DNA binding site [nucleotide binding]; other site
1035817002839	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817002840	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817002841	homodimer interface [polypeptide binding]; other site
1035817002842	catalytic residue [active]
1035817002843	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1035817002844	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
1035817002845	putative active site [active]
1035817002846	transaldolase; Provisional; Region: PRK03903
1035817002847	catalytic residue [active]
1035817002848	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1035817002849	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1035817002850	TPP-binding site [chemical binding]; other site
1035817002851	dimer interface [polypeptide binding]; other site
1035817002852	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1035817002853	PYR/PP interface [polypeptide binding]; other site
1035817002854	dimer interface [polypeptide binding]; other site
1035817002855	TPP binding site [chemical binding]; other site
1035817002856	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1035817002857	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1035817002858	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1035817002859	chaperone protein DnaJ; Provisional; Region: PRK14278
1035817002860	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1035817002861	HSP70 interaction site [polypeptide binding]; other site
1035817002862	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1035817002863	Zn binding sites [ion binding]; other site
1035817002864	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1035817002865	dimer interface [polypeptide binding]; other site
1035817002866	Fructosamine kinase; Region: Fructosamin_kin; cl17579
1035817002867	Phosphotransferase enzyme family; Region: APH; pfam01636
1035817002868	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554
1035817002869	PAC2 family; Region: PAC2; pfam09754
1035817002870	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1035817002871	thiS-thiF/thiG interaction site; other site
1035817002872	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
1035817002873	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1035817002874	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1035817002875	active site
1035817002876	dimer interface [polypeptide binding]; other site
1035817002877	motif 1; other site
1035817002878	motif 2; other site
1035817002879	motif 3; other site
1035817002880	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1035817002881	anticodon binding site; other site
1035817002882	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1035817002883	nucleotide binding site/active site [active]
1035817002884	HIT family signature motif; other site
1035817002885	catalytic residue [active]
1035817002886	hypothetical protein; Validated; Region: PRK00110
1035817002887	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1035817002888	active site
1035817002889	putative DNA-binding cleft [nucleotide binding]; other site
1035817002890	dimer interface [polypeptide binding]; other site
1035817002891	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1035817002892	RuvA N terminal domain; Region: RuvA_N; pfam01330
1035817002893	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1035817002894	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1035817002895	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817002896	Walker A motif; other site
1035817002897	ATP binding site [chemical binding]; other site
1035817002898	Walker B motif; other site
1035817002899	arginine finger; other site
1035817002900	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1035817002901	Preprotein translocase subunit; Region: YajC; pfam02699
1035817002902	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817002903	active site
1035817002904	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1035817002905	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1035817002906	CoA-ligase; Region: Ligase_CoA; pfam00549
1035817002907	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1035817002908	CoA binding domain; Region: CoA_binding; smart00881
1035817002909	CoA-ligase; Region: Ligase_CoA; pfam00549
1035817002910	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1035817002911	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1035817002912	purine monophosphate binding site [chemical binding]; other site
1035817002913	dimer interface [polypeptide binding]; other site
1035817002914	putative catalytic residues [active]
1035817002915	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1035817002916	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cl00200
1035817002917	amphipathic channel; other site
1035817002918	Asn-Pro-Ala signature motifs; other site
1035817002919	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1035817002920	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1035817002921	RNA binding surface [nucleotide binding]; other site
1035817002922	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1035817002923	active site
1035817002924	bifunctional cytidylate kinase/GTPase Der; Reviewed; Region: PRK09518
1035817002925	AAA domain; Region: AAA_17; pfam13207
1035817002926	Cytidylate kinase; Region: Cytidylate_kin; pfam02224
1035817002927	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1035817002928	G1 box; other site
1035817002929	GTP/Mg2+ binding site [chemical binding]; other site
1035817002930	Switch I region; other site
1035817002931	G2 box; other site
1035817002932	Switch II region; other site
1035817002933	G3 box; other site
1035817002934	G4 box; other site
1035817002935	G5 box; other site
1035817002936	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1035817002937	G1 box; other site
1035817002938	GTP/Mg2+ binding site [chemical binding]; other site
1035817002939	Switch I region; other site
1035817002940	G2 box; other site
1035817002941	G3 box; other site
1035817002942	Switch II region; other site
1035817002943	G4 box; other site
1035817002944	G5 box; other site
1035817002945	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1035817002946	active site
1035817002947	Predicted transcriptional regulator [Transcription]; Region: COG2378
1035817002948	WYL domain; Region: WYL; pfam13280
1035817002949	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1035817002950	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817002951	ATP binding site [chemical binding]; other site
1035817002952	putative Mg++ binding site [ion binding]; other site
1035817002953	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817002954	nucleotide binding region [chemical binding]; other site
1035817002955	ATP-binding site [chemical binding]; other site
1035817002956	DSHCT (NUC185) domain; Region: DSHCT; pfam08148
1035817002957	Domain of unknown function (DUF4109); Region: DUF4109; pfam13397
1035817002958	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1035817002959	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817002960	motif II; other site
1035817002961	potential frameshift: common BLAST hit: gi|312132706|ref|YP_004000045.1| phage integrase family protein
1035817002962	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817002963	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1035817002964	DNA binding site [nucleotide binding]
1035817002965	Int/Topo IB signature motif; other site
1035817002966	active site
1035817002967	catalytic residues [active]
1035817002968	Helix-turn-helix domain; Region: HTH_17; pfam12728
1035817002969	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
1035817002970	active site
1035817002971	catalytic site [active]
1035817002972	Bpu10I restriction endonuclease; Region: RE_Bpu10I; pfam09549
1035817002973	potential frameshift: common BLAST hit: gi|296454090|ref|YP_003661233.1| helicase domain-containing protein
1035817002974	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817002975	nucleotide binding region [chemical binding]; other site
1035817002976	ATP-binding site [chemical binding]; other site
1035817002977	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
1035817002978	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1035817002979	DNA methylase; Region: N6_N4_Mtase; cl17433
1035817002980	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817002981	Integrase core domain; Region: rve; pfam00665
1035817002982	transposase/IS protein; Provisional; Region: PRK09183
1035817002983	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817002984	Walker A motif; other site
1035817002985	ATP binding site [chemical binding]; other site
1035817002986	Walker B motif; other site
1035817002987	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817002988	Integrase core domain; Region: rve; pfam00665
1035817002989	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1035817002990	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1035817002991	DNA binding residues [nucleotide binding]
1035817002992	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1035817002993	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
1035817002994	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1035817002995	phosphopeptide binding site; other site
1035817002996	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3879
1035817002997	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1035817002998	Protein of unknown function (DUF1290); Region: DUF1290; pfam06947
1035817002999	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1035817003000	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1035817003001	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1035817003002	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1035817003003	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1035817003004	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs; Region: NTP-PPase_HisE; cd11547
1035817003005	homodimer interface [polypeptide binding]; other site
1035817003006	putative metal binding site [ion binding]; other site
1035817003007	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1035817003008	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1035817003009	substrate binding site [chemical binding]; other site
1035817003010	hexamer interface [polypeptide binding]; other site
1035817003011	metal binding site [ion binding]; metal-binding site
1035817003012	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1035817003013	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1035817003014	substrate binding site [chemical binding]; other site
1035817003015	active site
1035817003016	catalytic residues [active]
1035817003017	heterodimer interface [polypeptide binding]; other site
1035817003018	bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta; Provisional; Region: PRK13802
1035817003019	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1035817003020	active site
1035817003021	ribulose/triose binding site [chemical binding]; other site
1035817003022	phosphate binding site [ion binding]; other site
1035817003023	substrate (anthranilate) binding pocket [chemical binding]; other site
1035817003024	product (indole) binding pocket [chemical binding]; other site
1035817003025	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1035817003026	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817003027	catalytic residue [active]
1035817003028	endonuclease IV; Provisional; Region: PRK01060
1035817003029	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1035817003030	AP (apurinic/apyrimidinic) site pocket; other site
1035817003031	DNA interaction; other site
1035817003032	Metal-binding active site; metal-binding site
1035817003033	S-methylmethionine transporter; Provisional; Region: PRK11387
1035817003034	similar to truncated amino acid transport protein; BLNIAS_01461
1035817003035	VanZ like family; Region: VanZ; pfam04892
1035817003036	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817003037	Helix-turn-helix domain; Region: HTH_38; pfam13936
1035817003038	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817003039	Integrase core domain; Region: rve; pfam00665
1035817003040	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817003041	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1035817003042	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1035817003043	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817003044	Coenzyme A binding pocket [chemical binding]; other site
1035817003045	Uncharacterized protein conserved in bacteria (DUF2316); Region: DUF2316; cl01805
1035817003046	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1035817003047	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1035817003048	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1035817003049	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1035817003050	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1035817003051	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817003052	Walker A/P-loop; other site
1035817003053	ATP binding site [chemical binding]; other site
1035817003054	Q-loop/lid; other site
1035817003055	ABC transporter signature motif; other site
1035817003056	Walker B; other site
1035817003057	D-loop; other site
1035817003058	H-loop/switch region; other site
1035817003059	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817003060	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1035817003061	Histidine kinase; Region: HisKA_3; pfam07730
1035817003062	Threonine/homoserine efflux transporter [Amino acid transport and metabolism]; Region: rhtA; COG5006
1035817003063	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817003064	ABC transporter signature motif; other site
1035817003065	Walker B; other site
1035817003066	D-loop; other site
1035817003067	H-loop/switch region; other site
1035817003068	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817003069	Integrase core domain; Region: rve; pfam00665
1035817003070	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817003071	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817003072	active site
1035817003073	phosphorylation site [posttranslational modification]
1035817003074	intermolecular recognition site; other site
1035817003075	dimerization interface [polypeptide binding]; other site
1035817003076	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1035817003077	DNA binding residues [nucleotide binding]
1035817003078	dimerization interface [polypeptide binding]; other site
1035817003079	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1035817003080	Histidine kinase; Region: HisKA_3; pfam07730
1035817003081	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1035817003082	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817003083	AAA domain; Region: AAA_21; pfam13304
1035817003084	Walker A/P-loop; other site
1035817003085	ATP binding site [chemical binding]; other site
1035817003086	ABC transporter; Region: ABC_tran; pfam00005
1035817003087	Q-loop/lid; other site
1035817003088	ABC transporter signature motif; other site
1035817003089	Walker B; other site
1035817003090	D-loop; other site
1035817003091	H-loop/switch region; other site
1035817003092	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
1035817003093	potential frameshift: common BLAST hit: gi|189439363|ref|YP_001954444.1| Molybdenum cofactor biosynthesis enzyme
1035817003094	Molybdenum cofactor biosynthesis enzyme [Coenzyme metabolism]; Region: MoaA; COG2896
1035817003095	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1035817003096	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1035817003097	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
1035817003098	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
1035817003099	nudix motif; other site
1035817003100	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1035817003101	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1035817003102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817003103	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817003104	S-methylmethionine transporter; Provisional; Region: PRK11387
1035817003105	Spore germination protein; Region: Spore_permease; cl17796
1035817003106	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1035817003107	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1035817003108	Catalytic site [active]
1035817003109	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1035817003110	aspartate aminotransferase; Provisional; Region: PRK06836
1035817003111	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817003112	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817003113	homodimer interface [polypeptide binding]; other site
1035817003114	catalytic residue [active]
1035817003115	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
1035817003116	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1035817003117	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1035817003118	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817003119	motif II; other site
1035817003120	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1035817003121	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1035817003122	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1035817003123	dimerization interface [polypeptide binding]; other site
1035817003124	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
1035817003125	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817003126	active site
1035817003127	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1035817003128	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1035817003129	heterodimer interface [polypeptide binding]; other site
1035817003130	active site
1035817003131	FMN binding site [chemical binding]; other site
1035817003132	homodimer interface [polypeptide binding]; other site
1035817003133	substrate binding site [chemical binding]; other site
1035817003134	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1035817003135	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1035817003136	FAD binding pocket [chemical binding]; other site
1035817003137	FAD binding motif [chemical binding]; other site
1035817003138	phosphate binding motif [ion binding]; other site
1035817003139	beta-alpha-beta structure motif; other site
1035817003140	NAD binding pocket [chemical binding]; other site
1035817003141	Iron coordination center [ion binding]; other site
1035817003142	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1035817003143	active site
1035817003144	dimer interface [polypeptide binding]; other site
1035817003145	dihydroorotase; Validated; Region: pyrC; PRK09357
1035817003146	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1035817003147	active site
1035817003148	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1035817003149	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1035817003150	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1035817003151	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1035817003152	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1035817003153	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1035817003154	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Provisional; Region: PRK14109
1035817003155	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1035817003156	metal binding triad; other site
1035817003157	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1035817003158	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1035817003159	metal binding triad; other site
1035817003160	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1035817003161	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1035817003162	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1035817003163	active site
1035817003164	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1035817003165	FAD binding site [chemical binding]; other site
1035817003166	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1035817003167	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1035817003168	THF binding site; other site
1035817003169	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1035817003170	substrate binding site [chemical binding]; other site
1035817003171	THF binding site; other site
1035817003172	zinc-binding site [ion binding]; other site
1035817003173	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817003174	catalytic core [active]
1035817003175	tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Translation, ribosomal structure and biogenesis]; Region: GCD14; COG2519
1035817003176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817003177	S-adenosylmethionine binding site [chemical binding]; other site
1035817003178	Predicted esterase [General function prediction only]; Region: COG0400
1035817003179	putative hydrolase; Provisional; Region: PRK11460
1035817003180	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1035817003181	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817003182	active site
1035817003183	catalytic tetrad [active]
1035817003184	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1035817003185	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1035817003186	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817003187	MULE transposase domain; Region: MULE; pfam10551
1035817003188	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1035817003189	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
1035817003190	GIY-YIG domain of uncharacterized bacterial protein structurally related to COG3410; Region: GIY-YIG_COG3410; cd10439
1035817003191	GIY-YIG motif/motif A; other site
1035817003192	putative active site [active]
1035817003193	putative metal binding site [ion binding]; other site
1035817003194	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
1035817003195	Uncharacterized conserved protein [Function unknown]; Region: COG3410
1035817003196	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
1035817003197	homodimer interface [polypeptide binding]; other site
1035817003198	chemical substrate binding site [chemical binding]; other site
1035817003199	oligomer interface [polypeptide binding]; other site
1035817003200	metal binding site [ion binding]; metal-binding site
1035817003201	short chain dehydrogenase; Validated; Region: PRK06182
1035817003202	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1035817003203	NAD(P) binding site [chemical binding]; other site
1035817003204	active site
1035817003205	tellurium resistance terB-like protein; Region: terB_like; cl11965
1035817003206	metal binding site [ion binding]; metal-binding site
1035817003207	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; cl00614
1035817003208	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1035817003209	potential frameshift: common BLAST hit: gi|310287398|ref|YP_003938656.1| carbon-nitrogen hydrolase
1035817003210	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1035817003211	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1035817003212	active site
1035817003213	dimer interface [polypeptide binding]; other site
1035817003214	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1035817003215	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1035817003216	catalytic triad [active]
1035817003217	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817003218	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1035817003219	active site
1035817003220	motif I; other site
1035817003221	motif II; other site
1035817003222	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817003223	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1035817003224	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817003225	Walker A/P-loop; other site
1035817003226	ATP binding site [chemical binding]; other site
1035817003227	Q-loop/lid; other site
1035817003228	ABC transporter signature motif; other site
1035817003229	Walker B; other site
1035817003230	D-loop; other site
1035817003231	H-loop/switch region; other site
1035817003232	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
1035817003233	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1035817003234	Glycosyl hydrolases related to GH101 family; Region: GHL; pfam11308
1035817003235	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1035817003236	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1035817003237	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1035817003238	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1035817003239	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1035817003240	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1035817003241	active site
1035817003242	dimer interface [polypeptide binding]; other site
1035817003243	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1035817003244	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1035817003245	active site
1035817003246	FMN binding site [chemical binding]; other site
1035817003247	substrate binding site [chemical binding]; other site
1035817003248	3Fe-4S cluster binding site [ion binding]; other site
1035817003249	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1035817003250	domain interface; other site
1035817003251	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817003252	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817003253	Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]; Region: COG3804
1035817003254	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1035817003255	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817003256	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817003257	DNA binding site [nucleotide binding]
1035817003258	domain linker motif; other site
1035817003259	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1035817003260	ligand binding site [chemical binding]; other site
1035817003261	dimerization interface (open form) [polypeptide binding]; other site
1035817003262	dimerization interface (closed form) [polypeptide binding]; other site
1035817003263	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817003264	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1035817003265	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1035817003266	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1035817003267	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1035817003268	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817003269	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817003270	DNA binding site [nucleotide binding]
1035817003271	domain linker motif; other site
1035817003272	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817003273	dimerization interface [polypeptide binding]; other site
1035817003274	ligand binding site [chemical binding]; other site
1035817003275	coproporphyrinogen III oxidase; Validated; Region: PRK05628
1035817003276	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1035817003277	FeS/SAM binding site; other site
1035817003278	HemN C-terminal domain; Region: HemN_C; pfam06969
1035817003279	GTP-binding protein LepA; Provisional; Region: PRK05433
1035817003280	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1035817003281	G1 box; other site
1035817003282	putative GEF interaction site [polypeptide binding]; other site
1035817003283	GTP/Mg2+ binding site [chemical binding]; other site
1035817003284	Switch I region; other site
1035817003285	G2 box; other site
1035817003286	G3 box; other site
1035817003287	Switch II region; other site
1035817003288	G4 box; other site
1035817003289	G5 box; other site
1035817003290	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1035817003291	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1035817003292	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1035817003293	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1035817003294	UPF0126 domain; Region: UPF0126; pfam03458
1035817003295	Predicted membrane protein [Function unknown]; Region: COG2860
1035817003296	UPF0126 domain; Region: UPF0126; pfam03458
1035817003297	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1035817003298	homodimer interface [polypeptide binding]; other site
1035817003299	MazG family protein; Region: mazG; TIGR00444
1035817003300	metal binding site [ion binding]; metal-binding site
1035817003301	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1035817003302	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1035817003303	homodimer interface [polypeptide binding]; other site
1035817003304	substrate-cofactor binding pocket; other site
1035817003305	catalytic residue [active]
1035817003306	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1035817003307	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1035817003308	5S rRNA interface [nucleotide binding]; other site
1035817003309	CTC domain interface [polypeptide binding]; other site
1035817003310	L16 interface [polypeptide binding]; other site
1035817003311	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1035817003312	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1035817003313	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
1035817003314	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1035817003315	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1035817003316	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1035817003317	ligand binding site [chemical binding]; other site
1035817003318	homodimer interface [polypeptide binding]; other site
1035817003319	NAD(P) binding site [chemical binding]; other site
1035817003320	trimer interface B [polypeptide binding]; other site
1035817003321	trimer interface A [polypeptide binding]; other site
1035817003322	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1035817003323	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1035817003324	acyl-activating enzyme (AAE) consensus motif; other site
1035817003325	putative AMP binding site [chemical binding]; other site
1035817003326	putative active site [active]
1035817003327	putative CoA binding site [chemical binding]; other site
1035817003328	GTPase Era; Reviewed; Region: era; PRK00089
1035817003329	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1035817003330	G1 box; other site
1035817003331	GTP/Mg2+ binding site [chemical binding]; other site
1035817003332	Switch I region; other site
1035817003333	G2 box; other site
1035817003334	Switch II region; other site
1035817003335	G3 box; other site
1035817003336	G4 box; other site
1035817003337	G5 box; other site
1035817003338	KH domain; Region: KH_2; pfam07650
1035817003339	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1035817003340	Domain of unknown function DUF21; Region: DUF21; pfam01595
1035817003341	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1035817003342	Transporter associated domain; Region: CorC_HlyC; smart01091
1035817003343	metal-binding heat shock protein; Provisional; Region: PRK00016
1035817003344	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1035817003345	PhoH-like protein; Region: PhoH; pfam02562
1035817003346	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1035817003347	nucleotide binding site/active site [active]
1035817003348	HIT family signature motif; other site
1035817003349	catalytic residue [active]
1035817003350	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1035817003351	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1035817003352	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
1035817003353	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1035817003354	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00844
1035817003355	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1035817003356	ligand binding site; other site
1035817003357	oligomer interface; other site
1035817003358	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1035817003359	dimer interface [polypeptide binding]; other site
1035817003360	N-terminal domain interface [polypeptide binding]; other site
1035817003361	sulfate 1 binding site; other site
1035817003362	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1035817003363	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1035817003364	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1035817003365	trimerization site [polypeptide binding]; other site
1035817003366	active site
1035817003367	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1035817003368	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1035817003369	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1035817003370	catalytic residue [active]
1035817003371	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1035817003372	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1035817003373	Walker A/P-loop; other site
1035817003374	ATP binding site [chemical binding]; other site
1035817003375	Q-loop/lid; other site
1035817003376	ABC transporter signature motif; other site
1035817003377	Walker B; other site
1035817003378	D-loop; other site
1035817003379	H-loop/switch region; other site
1035817003380	FeS assembly protein SufD; Region: sufD; TIGR01981
1035817003381	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1035817003382	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1035817003383	FeS assembly protein SufB; Region: sufB; TIGR01980
1035817003384	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1035817003385	CTP synthetase; Validated; Region: pyrG; PRK05380
1035817003386	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1035817003387	Catalytic site [active]
1035817003388	active site
1035817003389	UTP binding site [chemical binding]; other site
1035817003390	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1035817003391	active site
1035817003392	putative oxyanion hole; other site
1035817003393	catalytic triad [active]
1035817003394	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1035817003395	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1035817003396	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1035817003397	trimer interface [polypeptide binding]; other site
1035817003398	active site
1035817003399	dimer interface [polypeptide binding]; other site
1035817003400	bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional; Region: PRK14021
1035817003401	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1035817003402	ADP binding site [chemical binding]; other site
1035817003403	magnesium binding site [ion binding]; other site
1035817003404	putative shikimate binding site; other site
1035817003405	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1035817003406	active site
1035817003407	dimer interface [polypeptide binding]; other site
1035817003408	metal binding site [ion binding]; metal-binding site
1035817003409	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1035817003410	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1035817003411	Tetramer interface [polypeptide binding]; other site
1035817003412	active site
1035817003413	FMN-binding site [chemical binding]; other site
1035817003414	YceG-like family; Region: YceG; pfam02618
1035817003415	proteins similar to Escherichia coli yceG; Region: yceG_like; cl17666
1035817003416	dimerization interface [polypeptide binding]; other site
1035817003417	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1035817003418	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1035817003419	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1035817003420	motif 1; other site
1035817003421	active site
1035817003422	motif 2; other site
1035817003423	motif 3; other site
1035817003424	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1035817003425	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
1035817003426	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817003427	catalytic core [active]
1035817003428	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1035817003429	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1035817003430	catalytic triad [active]
1035817003431	catalytic triad [active]
1035817003432	oxyanion hole [active]
1035817003433	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1035817003434	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1035817003435	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1035817003436	RNA binding surface [nucleotide binding]; other site
1035817003437	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1035817003438	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817003439	Walker A/P-loop; other site
1035817003440	ATP binding site [chemical binding]; other site
1035817003441	Q-loop/lid; other site
1035817003442	ABC transporter signature motif; other site
1035817003443	Walker B; other site
1035817003444	D-loop; other site
1035817003445	H-loop/switch region; other site
1035817003446	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817003447	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817003448	FtsX-like permease family; Region: FtsX; pfam02687
1035817003449	Domain of unknown function (DUF4418); Region: DUF4418; pfam14387
1035817003450	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1035817003451	Part of AAA domain; Region: AAA_19; pfam13245
1035817003452	Family description; Region: UvrD_C_2; pfam13538
1035817003453	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817003454	active site
1035817003455	xanthine permease; Region: pbuX; TIGR03173
1035817003456	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817003457	salt bridge; other site
1035817003458	non-specific DNA binding site [nucleotide binding]; other site
1035817003459	sequence-specific DNA binding site [nucleotide binding]; other site
1035817003460	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
1035817003461	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1035817003462	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1035817003463	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1035817003464	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1035817003465	Isochorismatase family; Region: Isochorismatase; pfam00857
1035817003466	catalytic triad [active]
1035817003467	metal binding site [ion binding]; metal-binding site
1035817003468	conserved cis-peptide bond; other site
1035817003469	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1035817003470	Divergent AAA domain; Region: AAA_4; pfam04326
1035817003471	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1035817003472	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1035817003473	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1035817003474	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1035817003475	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1035817003476	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1035817003477	Walker A/P-loop; other site
1035817003478	ATP binding site [chemical binding]; other site
1035817003479	Q-loop/lid; other site
1035817003480	ABC transporter signature motif; other site
1035817003481	Walker B; other site
1035817003482	D-loop; other site
1035817003483	H-loop/switch region; other site
1035817003484	Histidine kinase; Region: HisKA_3; pfam07730
1035817003485	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1035817003486	ATP binding site [chemical binding]; other site
1035817003487	Mg2+ binding site [ion binding]; other site
1035817003488	G-X-G motif; other site
1035817003489	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817003490	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817003491	active site
1035817003492	phosphorylation site [posttranslational modification]
1035817003493	intermolecular recognition site; other site
1035817003494	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1035817003495	DNA binding residues [nucleotide binding]
1035817003496	dimerization interface [polypeptide binding]; other site
1035817003497	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1035817003498	Phosphate transporter family; Region: PHO4; pfam01384
1035817003499	Protein of unknown function (DUF466); Region: DUF466; cl01082
1035817003500	carbon starvation protein A; Provisional; Region: PRK15015
1035817003501	Carbon starvation protein CstA; Region: CstA; pfam02554
1035817003502	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1035817003503	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like; cd11354
1035817003504	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1035817003505	active site
1035817003506	catalytic site [active]
1035817003507	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817003508	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817003509	WHG domain; Region: WHG; pfam13305
1035817003510	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1035817003511	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1035817003512	ATP binding site [chemical binding]; other site
1035817003513	putative Mg++ binding site [ion binding]; other site
1035817003514	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817003515	nucleotide binding region [chemical binding]; other site
1035817003516	ATP-binding site [chemical binding]; other site
1035817003517	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1035817003518	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817003519	catalytic core [active]
1035817003520	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1035817003521	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1035817003522	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817003523	non-specific DNA binding site [nucleotide binding]; other site
1035817003524	salt bridge; other site
1035817003525	sequence-specific DNA binding site [nucleotide binding]; other site
1035817003526	Excalibur calcium-binding domain; Region: Excalibur; smart00894
1035817003527	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817003528	MULE transposase domain; Region: MULE; pfam10551
1035817003529	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
1035817003530	Short C-terminal domain; Region: SHOCT; pfam09851
1035817003531	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
1035817003532	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817003533	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1035817003534	active site
1035817003535	ATP binding site [chemical binding]; other site
1035817003536	substrate binding site [chemical binding]; other site
1035817003537	activation loop (A-loop); other site
1035817003538	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817003539	H+ Antiporter protein; Region: 2A0121; TIGR00900
1035817003540	putative substrate translocation pore; other site
1035817003541	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817003542	putative substrate translocation pore; other site
1035817003543	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817003544	FOG: CBS domain [General function prediction only]; Region: COG0517
1035817003545	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_23; cd04636
1035817003546	hypothetical protein; Provisional; Region: PRK11770
1035817003547	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1035817003548	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1035817003549	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1035817003550	active site
1035817003551	metal binding site [ion binding]; metal-binding site
1035817003552	hypothetical protein; Provisional; Region: PRK06762
1035817003553	AAA domain; Region: AAA_33; pfam13671
1035817003554	RNA ligase; Region: RNA_lig_T4_1; pfam09511
1035817003555	Domain of unknown function DUF1829; Region: DUF1829; pfam08862
1035817003556	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1035817003557	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817003558	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817003559	active site
1035817003560	DNA binding site [nucleotide binding]
1035817003561	Int/Topo IB signature motif; other site
1035817003562	GTP-binding protein YchF; Reviewed; Region: PRK09601
1035817003563	YchF GTPase; Region: YchF; cd01900
1035817003564	G1 box; other site
1035817003565	GTP/Mg2+ binding site [chemical binding]; other site
1035817003566	Switch I region; other site
1035817003567	G2 box; other site
1035817003568	Switch II region; other site
1035817003569	G3 box; other site
1035817003570	G4 box; other site
1035817003571	G5 box; other site
1035817003572	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1035817003573	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1035817003574	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1035817003575	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1035817003576	Histidine kinase; Region: HisKA_3; pfam07730
1035817003577	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817003578	ATP binding site [chemical binding]; other site
1035817003579	Mg2+ binding site [ion binding]; other site
1035817003580	G-X-G motif; other site
1035817003581	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1035817003582	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1035817003583	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817003584	active site
1035817003585	phosphorylation site [posttranslational modification]
1035817003586	intermolecular recognition site; other site
1035817003587	dimerization interface [polypeptide binding]; other site
1035817003588	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1035817003589	DNA binding residues [nucleotide binding]
1035817003590	dimerization interface [polypeptide binding]; other site
1035817003591	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817003592	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817003593	FtsX-like permease family; Region: FtsX; pfam02687
1035817003594	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817003595	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817003596	Walker A/P-loop; other site
1035817003597	ATP binding site [chemical binding]; other site
1035817003598	Q-loop/lid; other site
1035817003599	ABC transporter signature motif; other site
1035817003600	Walker B; other site
1035817003601	D-loop; other site
1035817003602	H-loop/switch region; other site
1035817003603	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1035817003604	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1035817003605	homodimer interface [polypeptide binding]; other site
1035817003606	substrate-cofactor binding pocket; other site
1035817003607	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817003608	catalytic residue [active]
1035817003609	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1035817003610	dimer interface [polypeptide binding]; other site
1035817003611	pyridoxal binding site [chemical binding]; other site
1035817003612	ATP binding site [chemical binding]; other site
1035817003613	hypothetical protein; Provisional; Region: PRK14681
1035817003614	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1035817003615	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1035817003616	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817003617	Walker A motif; other site
1035817003618	ATP binding site [chemical binding]; other site
1035817003619	Walker B motif; other site
1035817003620	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1035817003621	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1035817003622	DNA protecting protein DprA; Region: dprA; TIGR00732
1035817003623	L-aspartate oxidase; Provisional; Region: PRK06175
1035817003624	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08205
1035817003625	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1035817003626	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1035817003627	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Region: FrdB; COG0479
1035817003628	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1035817003629	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1035817003630	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1035817003631	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
1035817003632	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1035817003633	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1035817003634	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817003635	Walker A motif; other site
1035817003636	ATP binding site [chemical binding]; other site
1035817003637	Walker B motif; other site
1035817003638	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1035817003639	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
1035817003640	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1035817003641	oligomer interface [polypeptide binding]; other site
1035817003642	active site residues [active]
1035817003643	Clp protease; Region: CLP_protease; pfam00574
1035817003644	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1035817003645	oligomer interface [polypeptide binding]; other site
1035817003646	active site residues [active]
1035817003647	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
1035817003648	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1035817003649	putative ion selectivity filter; other site
1035817003650	putative pore gating glutamate residue; other site
1035817003651	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1035817003652	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
1035817003653	dimer interface [polypeptide binding]; other site
1035817003654	trigger factor; Provisional; Region: tig; PRK01490
1035817003655	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1035817003656	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1035817003657	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1035817003658	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1035817003659	active site
1035817003660	catalytic site [active]
1035817003661	substrate binding site [chemical binding]; other site
1035817003662	HRDC domain; Region: HRDC; pfam00570
1035817003663	Protein of unknown function (DUF3000); Region: DUF3000; pfam11452
1035817003664	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
1035817003665	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1035817003666	FeS/SAM binding site; other site
1035817003667	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1035817003668	Pyruvate formate lyase 1; Region: PFL1; cd01678
1035817003669	coenzyme A binding site [chemical binding]; other site
1035817003670	active site
1035817003671	catalytic residues [active]
1035817003672	glycine loop; other site
1035817003673	NAD synthetase; Provisional; Region: PRK13981
1035817003674	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1035817003675	multimer interface [polypeptide binding]; other site
1035817003676	active site
1035817003677	catalytic triad [active]
1035817003678	protein interface 1 [polypeptide binding]; other site
1035817003679	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1035817003680	homodimer interface [polypeptide binding]; other site
1035817003681	NAD binding pocket [chemical binding]; other site
1035817003682	ATP binding pocket [chemical binding]; other site
1035817003683	Mg binding site [ion binding]; other site
1035817003684	active-site loop [active]
1035817003685	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1035817003686	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1035817003687	metal binding site [ion binding]; metal-binding site
1035817003688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1035817003689	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1035817003690	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1035817003691	Walker A/P-loop; other site
1035817003692	ATP binding site [chemical binding]; other site
1035817003693	Q-loop/lid; other site
1035817003694	ABC transporter signature motif; other site
1035817003695	Walker B; other site
1035817003696	D-loop; other site
1035817003697	H-loop/switch region; other site
1035817003698	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1035817003699	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1035817003700	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1035817003701	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1035817003702	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817003703	active site
1035817003704	motif I; other site
1035817003705	motif II; other site
1035817003706	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1035817003707	putative phosphoketolase; Provisional; Region: PRK05261
1035817003708	XFP N-terminal domain; Region: XFP_N; pfam09364
1035817003709	XFP C-terminal domain; Region: XFP_C; pfam09363
1035817003710	GMP synthase; Reviewed; Region: guaA; PRK00074
1035817003711	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1035817003712	AMP/PPi binding site [chemical binding]; other site
1035817003713	candidate oxyanion hole; other site
1035817003714	catalytic triad [active]
1035817003715	potential glutamine specificity residues [chemical binding]; other site
1035817003716	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1035817003717	ATP Binding subdomain [chemical binding]; other site
1035817003718	Ligand Binding sites [chemical binding]; other site
1035817003719	Dimerization subdomain; other site
1035817003720	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
1035817003721	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
1035817003722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817003723	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817003724	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
1035817003725	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
1035817003726	hypothetical protein; Provisional; Region: PRK13663
1035817003727	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1035817003728	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1035817003729	catalytic triad [active]
1035817003730	catalytic triad [active]
1035817003731	oxyanion hole [active]
1035817003732	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1035817003733	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK03092
1035817003734	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817003735	active site
1035817003736	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14352
1035817003737	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1035817003738	Substrate binding site; other site
1035817003739	Mg++ binding site; other site
1035817003740	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1035817003741	active site
1035817003742	substrate binding site [chemical binding]; other site
1035817003743	CoA binding site [chemical binding]; other site
1035817003744	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1035817003745	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817003746	catalytic core [active]
1035817003747	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1035817003748	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1035817003749	propionate/acetate kinase; Provisional; Region: PRK12379
1035817003750	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1035817003751	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1035817003752	hinge; other site
1035817003753	active site
1035817003754	similar to truncated beta-galactosidase; BLNIAS_01825
1035817003755	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1035817003756	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1035817003757	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1035817003758	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1035817003759	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1035817003760	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1035817003761	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1035817003762	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1035817003763	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1035817003764	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1035817003765	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817003766	non-specific DNA binding site [nucleotide binding]; other site
1035817003767	salt bridge; other site
1035817003768	sequence-specific DNA binding site [nucleotide binding]; other site
1035817003769	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
1035817003770	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1035817003771	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1035817003772	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1035817003773	active site
1035817003774	catalytic site [active]
1035817003775	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1035817003776	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1035817003777	dimer interface [polypeptide binding]; other site
1035817003778	ADP-ribose binding site [chemical binding]; other site
1035817003779	active site
1035817003780	nudix motif; other site
1035817003781	metal binding site [ion binding]; metal-binding site
1035817003782	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1035817003783	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1035817003784	DNA polymerase I; Provisional; Region: PRK05755
1035817003785	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1035817003786	active site
1035817003787	metal binding site 1 [ion binding]; metal-binding site
1035817003788	putative 5' ssDNA interaction site; other site
1035817003789	metal binding site 3; metal-binding site
1035817003790	metal binding site 2 [ion binding]; metal-binding site
1035817003791	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1035817003792	putative DNA binding site [nucleotide binding]; other site
1035817003793	putative metal binding site [ion binding]; other site
1035817003794	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1035817003795	active site
1035817003796	substrate binding site [chemical binding]; other site
1035817003797	catalytic site [active]
1035817003798	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1035817003799	active site
1035817003800	DNA binding site [nucleotide binding]
1035817003801	catalytic site [active]
1035817003802	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
1035817003803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817003804	active site
1035817003805	phosphorylation site [posttranslational modification]
1035817003806	intermolecular recognition site; other site
1035817003807	dimerization interface [polypeptide binding]; other site
1035817003808	ANTAR domain; Region: ANTAR; pfam03861
1035817003809	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1035817003810	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1035817003811	dimer interface [polypeptide binding]; other site
1035817003812	ADP-ribose binding site [chemical binding]; other site
1035817003813	active site
1035817003814	nudix motif; other site
1035817003815	metal binding site [ion binding]; metal-binding site
1035817003816	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1035817003817	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1035817003818	domain interfaces; other site
1035817003819	active site
1035817003820	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1035817003821	excinuclease ABC subunit B; Provisional; Region: PRK05298
1035817003822	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817003823	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817003824	nucleotide binding region [chemical binding]; other site
1035817003825	ATP-binding site [chemical binding]; other site
1035817003826	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1035817003827	UvrB/uvrC motif; Region: UVR; pfam02151
1035817003828	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1035817003829	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1035817003830	CoA-binding site [chemical binding]; other site
1035817003831	ATP-binding [chemical binding]; other site
1035817003832	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK07899
1035817003833	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1035817003834	RNA binding site [nucleotide binding]; other site
1035817003835	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1035817003836	RNA binding site [nucleotide binding]; other site
1035817003837	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1035817003838	RNA binding site [nucleotide binding]; other site
1035817003839	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1035817003840	RNA binding site [nucleotide binding]; other site
1035817003841	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14193
1035817003842	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1035817003843	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1035817003844	homodimer interface [polypeptide binding]; other site
1035817003845	NADP binding site [chemical binding]; other site
1035817003846	substrate binding site [chemical binding]; other site
1035817003847	Metal binding protein TroA_b.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020
1035817003848	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1035817003849	metal binding site [ion binding]; metal-binding site
1035817003850	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1035817003851	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1035817003852	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1035817003853	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1035817003854	ABC-ATPase subunit  interface; other site
1035817003855	dimer interface [polypeptide binding]; other site
1035817003856	putative PBP binding regions; other site
1035817003857	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1035817003858	homotrimer interaction site [polypeptide binding]; other site
1035817003859	zinc binding site [ion binding]; other site
1035817003860	CDP-binding sites; other site
1035817003861	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
1035817003862	glycogen branching enzyme; Provisional; Region: PRK05402
1035817003863	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1035817003864	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1035817003865	active site
1035817003866	catalytic site [active]
1035817003867	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1035817003868	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817003869	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817003870	active site
1035817003871	phosphorylation site [posttranslational modification]
1035817003872	intermolecular recognition site; other site
1035817003873	dimerization interface [polypeptide binding]; other site
1035817003874	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1035817003875	DNA binding site [nucleotide binding]
1035817003876	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1035817003877	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1035817003878	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1035817003879	dimerization interface [polypeptide binding]; other site
1035817003880	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1035817003881	dimer interface [polypeptide binding]; other site
1035817003882	phosphorylation site [posttranslational modification]
1035817003883	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817003884	ATP binding site [chemical binding]; other site
1035817003885	Mg2+ binding site [ion binding]; other site
1035817003886	G-X-G motif; other site
1035817003887	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1035817003888	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817003889	active site
1035817003890	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
1035817003891	Eukaryotic phosphomannomutase; Region: PMM; cl17107
1035817003892	Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria; Region: MMP_TTHA0227_like_1; cd12954
1035817003893	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1035817003894	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1035817003895	Transcription factor WhiB; Region: Whib; pfam02467
1035817003896	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; pfam03816
1035817003897	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1035817003898	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817003899	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1035817003900	Walker A/P-loop; other site
1035817003901	ATP binding site [chemical binding]; other site
1035817003902	Transcription factor WhiB; Region: Whib; pfam02467
1035817003903	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
1035817003904	PAS fold; Region: PAS_4; pfam08448
1035817003905	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1035817003906	Histidine kinase; Region: HisKA_2; pfam07568
1035817003907	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817003908	ATP binding site [chemical binding]; other site
1035817003909	Mg2+ binding site [ion binding]; other site
1035817003910	G-X-G motif; other site
1035817003911	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1035817003912	Haemolysin-III related; Region: HlyIII; pfam03006
1035817003913	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1035817003914	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1035817003915	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1035817003916	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1035817003917	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1035817003918	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1035817003919	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1035817003920	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1035817003921	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1035817003922	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1035817003923	Protein of unknown function (DUF501); Region: DUF501; pfam04417
1035817003924	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1035817003925	Septum formation initiator; Region: DivIC; pfam04977
1035817003926	enolase; Provisional; Region: eno; PRK00077
1035817003927	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1035817003928	dimer interface [polypeptide binding]; other site
1035817003929	metal binding site [ion binding]; metal-binding site
1035817003930	substrate binding pocket [chemical binding]; other site
1035817003931	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817003932	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817003933	active site
1035817003934	catalytic tetrad [active]
1035817003935	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1035817003936	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1035817003937	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817003938	ATP binding site [chemical binding]; other site
1035817003939	putative Mg++ binding site [ion binding]; other site
1035817003940	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817003941	nucleotide binding region [chemical binding]; other site
1035817003942	ATP-binding site [chemical binding]; other site
1035817003943	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1035817003944	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1035817003945	putative active site [active]
1035817003946	catalytic residue [active]
1035817003947	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1035817003948	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817003949	Coenzyme A binding pocket [chemical binding]; other site
1035817003950	Uncharacterized protein family (UPF0182); Region: UPF0182; pfam03699
1035817003951	Uncharacterized conserved protein [Function unknown]; Region: COG1615
1035817003952	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1035817003953	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1035817003954	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1035817003955	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1035817003956	active site
1035817003957	(T/H)XGH motif; other site
1035817003958	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1035817003959	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1035817003960	putative catalytic cysteine [active]
1035817003961	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817003962	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817003963	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1035817003964	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1035817003965	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817003966	catalytic residue [active]
1035817003967	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1035817003968	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1035817003969	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1035817003970	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1035817003971	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1035817003972	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1035817003973	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1035817003974	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
1035817003975	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1035817003976	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1035817003977	Walker A/P-loop; other site
1035817003978	ATP binding site [chemical binding]; other site
1035817003979	Q-loop/lid; other site
1035817003980	ABC transporter signature motif; other site
1035817003981	Walker B; other site
1035817003982	D-loop; other site
1035817003983	H-loop/switch region; other site
1035817003984	Predicted transcriptional regulators [Transcription]; Region: COG1725
1035817003985	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1035817003986	DNA-binding site [nucleotide binding]; DNA binding site
1035817003987	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1035817003988	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817003989	motif II; other site
1035817003990	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1035817003991	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1035817003992	Walker A/P-loop; other site
1035817003993	ATP binding site [chemical binding]; other site
1035817003994	Q-loop/lid; other site
1035817003995	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1035817003996	ABC transporter signature motif; other site
1035817003997	Walker B; other site
1035817003998	D-loop; other site
1035817003999	H-loop/switch region; other site
1035817004000	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03372
1035817004001	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
1035817004002	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1035817004003	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1035817004004	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1035817004005	TrkA-N domain; Region: TrkA_N; pfam02254
1035817004006	TrkA-C domain; Region: TrkA_C; pfam02080
1035817004007	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1035817004008	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1035817004009	RNA binding surface [nucleotide binding]; other site
1035817004010	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817004011	S-adenosylmethionine binding site [chemical binding]; other site
1035817004012	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
1035817004013	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817004014	active site
1035817004015	motif I; other site
1035817004016	motif II; other site
1035817004017	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1035817004018	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1035817004019	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1035817004020	active site
1035817004021	HIGH motif; other site
1035817004022	dimer interface [polypeptide binding]; other site
1035817004023	KMSKS motif; other site
1035817004024	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1035817004025	RNA binding surface [nucleotide binding]; other site
1035817004026	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
1035817004027	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1035817004028	Zn2+ binding site [ion binding]; other site
1035817004029	Mg2+ binding site [ion binding]; other site
1035817004030	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1035817004031	active site residue [active]
1035817004032	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1035817004033	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1035817004034	ATP binding site [chemical binding]; other site
1035817004035	substrate interface [chemical binding]; other site
1035817004036	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1035817004037	ThiS interaction site; other site
1035817004038	putative active site [active]
1035817004039	tetramer interface [polypeptide binding]; other site
1035817004040	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1035817004041	thiS-thiF/thiG interaction site; other site
1035817004042	argininosuccinate lyase; Provisional; Region: PRK00855
1035817004043	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1035817004044	active sites [active]
1035817004045	tetramer interface [polypeptide binding]; other site
1035817004046	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1035817004047	argininosuccinate synthase; Provisional; Region: PRK13820
1035817004048	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1035817004049	ANP binding site [chemical binding]; other site
1035817004050	Substrate Binding Site II [chemical binding]; other site
1035817004051	Substrate Binding Site I [chemical binding]; other site
1035817004052	arginine repressor; Provisional; Region: PRK03341
1035817004053	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1035817004054	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1035817004055	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1035817004056	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1035817004057	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1035817004058	acetylornithine aminotransferase; Provisional; Region: argD; PRK03244
1035817004059	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1035817004060	inhibitor-cofactor binding pocket; inhibition site
1035817004061	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817004062	catalytic residue [active]
1035817004063	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
1035817004064	feedback inhibition sensing region; other site
1035817004065	homohexameric interface [polypeptide binding]; other site
1035817004066	nucleotide binding site [chemical binding]; other site
1035817004067	N-acetyl-L-glutamate binding site [chemical binding]; other site
1035817004068	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1035817004069	heterotetramer interface [polypeptide binding]; other site
1035817004070	active site pocket [active]
1035817004071	cleavage site
1035817004072	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1035817004073	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1035817004074	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
1035817004075	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1035817004076	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1035817004077	putative tRNA-binding site [nucleotide binding]; other site
1035817004078	B3/4 domain; Region: B3_4; pfam03483
1035817004079	tRNA synthetase B5 domain; Region: B5; pfam03484
1035817004080	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1035817004081	dimer interface [polypeptide binding]; other site
1035817004082	motif 1; other site
1035817004083	motif 3; other site
1035817004084	motif 2; other site
1035817004085	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1035817004086	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1035817004087	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1035817004088	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1035817004089	dimer interface [polypeptide binding]; other site
1035817004090	motif 1; other site
1035817004091	active site
1035817004092	motif 2; other site
1035817004093	motif 3; other site
1035817004094	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1035817004095	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; cl06870
1035817004096	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1035817004097	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1035817004098	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817004099	cobalt transport protein ATP-binding subunit; Region: cbiO; TIGR01166
1035817004100	Walker A/P-loop; other site
1035817004101	ATP binding site [chemical binding]; other site
1035817004102	Q-loop/lid; other site
1035817004103	ABC transporter signature motif; other site
1035817004104	Walker B; other site
1035817004105	D-loop; other site
1035817004106	H-loop/switch region; other site
1035817004107	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1035817004108	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1035817004109	Walker A/P-loop; other site
1035817004110	ATP binding site [chemical binding]; other site
1035817004111	Q-loop/lid; other site
1035817004112	ABC transporter signature motif; other site
1035817004113	Walker B; other site
1035817004114	D-loop; other site
1035817004115	H-loop/switch region; other site
1035817004116	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
1035817004117	hypothetical protein; Provisional; Region: PRK07907
1035817004118	M20 Dipeptidases; Region: M20_Dipept_like; cd03893
1035817004119	active site
1035817004120	metal binding site [ion binding]; metal-binding site
1035817004121	dimer interface [polypeptide binding]; other site
1035817004122	Protein of unknown function (DUF3043); Region: DUF3043; pfam11241
1035817004123	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1035817004124	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1035817004125	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1035817004126	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1035817004127	Domain of unknown function (DUF4191); Region: DUF4191; pfam13829
1035817004128	glutamine synthetase, type I; Region: GlnA; TIGR00653
1035817004129	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1035817004130	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1035817004131	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1035817004132	Predicted permeases [General function prediction only]; Region: COG0679
1035817004133	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1035817004134	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1035817004135	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004136	Walker A/P-loop; other site
1035817004137	ATP binding site [chemical binding]; other site
1035817004138	Q-loop/lid; other site
1035817004139	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004140	ABC transporter signature motif; other site
1035817004141	Walker B; other site
1035817004142	D-loop; other site
1035817004143	H-loop/switch region; other site
1035817004144	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004145	Walker A/P-loop; other site
1035817004146	ATP binding site [chemical binding]; other site
1035817004147	Q-loop/lid; other site
1035817004148	ABC transporter signature motif; other site
1035817004149	Walker B; other site
1035817004150	D-loop; other site
1035817004151	H-loop/switch region; other site
1035817004152	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
1035817004153	AAA domain; Region: AAA_14; pfam13173
1035817004154	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1035817004155	KDPG and KHG aldolase; Region: Aldolase; cl17259
1035817004156	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1035817004157	MarR family; Region: MarR_2; pfam12802
1035817004158	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1035817004159	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1035817004160	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1035817004161	AAA domain; Region: AAA_14; pfam13173
1035817004162	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1035817004163	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH3; cd08287
1035817004164	catalytic Zn binding site [ion binding]; other site
1035817004165	NAD(P) binding site [chemical binding]; other site
1035817004166	structural Zn binding site [ion binding]; other site
1035817004167	CrcB-like protein; Region: CRCB; pfam02537
1035817004168	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
1035817004169	Predicted membrane protein [Function unknown]; Region: COG2246
1035817004170	GtrA-like protein; Region: GtrA; pfam04138
1035817004171	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1035817004172	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1035817004173	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1035817004174	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1035817004175	dimerization interface [polypeptide binding]; other site
1035817004176	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
1035817004177	elongation factor Tu; Reviewed; Region: PRK00049
1035817004178	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1035817004179	G1 box; other site
1035817004180	GEF interaction site [polypeptide binding]; other site
1035817004181	GTP/Mg2+ binding site [chemical binding]; other site
1035817004182	Switch I region; other site
1035817004183	G2 box; other site
1035817004184	G3 box; other site
1035817004185	Switch II region; other site
1035817004186	G4 box; other site
1035817004187	G5 box; other site
1035817004188	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1035817004189	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1035817004190	Antibiotic Binding Site [chemical binding]; other site
1035817004191	elongation factor G; Reviewed; Region: PRK00007
1035817004192	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1035817004193	G1 box; other site
1035817004194	putative GEF interaction site [polypeptide binding]; other site
1035817004195	GTP/Mg2+ binding site [chemical binding]; other site
1035817004196	Switch I region; other site
1035817004197	G2 box; other site
1035817004198	G3 box; other site
1035817004199	Switch II region; other site
1035817004200	G4 box; other site
1035817004201	G5 box; other site
1035817004202	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1035817004203	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1035817004204	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1035817004205	30S ribosomal protein S7; Validated; Region: PRK05302
1035817004206	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1035817004207	S17 interaction site [polypeptide binding]; other site
1035817004208	S8 interaction site; other site
1035817004209	16S rRNA interaction site [nucleotide binding]; other site
1035817004210	streptomycin interaction site [chemical binding]; other site
1035817004211	23S rRNA interaction site [nucleotide binding]; other site
1035817004212	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1035817004213	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1035817004214	Sodium Bile acid symporter family; Region: SBF; pfam01758
1035817004215	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1035817004216	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1035817004217	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1035817004218	catalytic residue [active]
1035817004219	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
1035817004220	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1035817004221	putative ADP-binding pocket [chemical binding]; other site
1035817004222	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1035817004223	ATP-grasp domain; Region: ATP-grasp; pfam02222
1035817004224	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1035817004225	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1035817004226	ATP binding site [chemical binding]; other site
1035817004227	active site
1035817004228	substrate binding site [chemical binding]; other site
1035817004229	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
1035817004230	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1035817004231	dimerization interface [polypeptide binding]; other site
1035817004232	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1035817004233	dimerization interface [polypeptide binding]; other site
1035817004234	ATP binding site [chemical binding]; other site
1035817004235	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1035817004236	dimerization interface [polypeptide binding]; other site
1035817004237	ATP binding site [chemical binding]; other site
1035817004238	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1035817004239	putative active site [active]
1035817004240	catalytic triad [active]
1035817004241	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1035817004242	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1035817004243	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1035817004244	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1035817004245	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1035817004246	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1035817004247	dimerization interface [polypeptide binding]; other site
1035817004248	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817004249	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817004250	active site
1035817004251	catalytic tetrad [active]
1035817004252	DNA polymerase IV; Reviewed; Region: PRK03103
1035817004253	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1035817004254	active site
1035817004255	DNA binding site [nucleotide binding]
1035817004256	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1035817004257	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1035817004258	NAD binding site [chemical binding]; other site
1035817004259	guanine deaminase; Region: guan_deamin; TIGR02967
1035817004260	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
1035817004261	active site
1035817004262	Cupin superfamily (DUF985); Region: Cupin_5; pfam06172
1035817004263	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817004264	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1035817004265	substrate binding pocket [chemical binding]; other site
1035817004266	membrane-bound complex binding site; other site
1035817004267	hinge residues; other site
1035817004268	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004269	dimer interface [polypeptide binding]; other site
1035817004270	conserved gate region; other site
1035817004271	putative PBP binding loops; other site
1035817004272	ABC-ATPase subunit interface; other site
1035817004273	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1035817004274	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1035817004275	Walker A/P-loop; other site
1035817004276	ATP binding site [chemical binding]; other site
1035817004277	Q-loop/lid; other site
1035817004278	ABC transporter signature motif; other site
1035817004279	Walker B; other site
1035817004280	D-loop; other site
1035817004281	H-loop/switch region; other site
1035817004282	amidophosphoribosyltransferase; Provisional; Region: PRK07272
1035817004283	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1035817004284	active site
1035817004285	tetramer interface [polypeptide binding]; other site
1035817004286	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817004287	active site
1035817004288	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1035817004289	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1035817004290	dimerization interface [polypeptide binding]; other site
1035817004291	putative ATP binding site [chemical binding]; other site
1035817004292	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1035817004293	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1035817004294	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1035817004295	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1035817004296	ALDH subfamily: Coniferyl aldehyde dehydrogenase, ALDH families 3, 13, and 14, and other related proteins; Region: ALDH_F3-13-14_CALDH-like; cd07087
1035817004297	NAD(P) binding site [chemical binding]; other site
1035817004298	catalytic residues [active]
1035817004299	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1035817004300	Sulfatase; Region: Sulfatase; pfam00884
1035817004301	Metal binding protein TroA_b.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020
1035817004302	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1035817004303	metal binding site [ion binding]; metal-binding site
1035817004304	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1035817004305	metal binding site 2 [ion binding]; metal-binding site
1035817004306	putative DNA binding helix; other site
1035817004307	metal binding site 1 [ion binding]; metal-binding site
1035817004308	dimer interface [polypeptide binding]; other site
1035817004309	structural Zn2+ binding site [ion binding]; other site
1035817004310	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1035817004311	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1035817004312	NAD binding site [chemical binding]; other site
1035817004313	ATP-grasp domain; Region: ATP-grasp; pfam02222
1035817004314	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1035817004315	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1035817004316	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1035817004317	NAD(P) binding site [chemical binding]; other site
1035817004318	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
1035817004319	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1035817004320	TPP-binding site; other site
1035817004321	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1035817004322	PYR/PP interface [polypeptide binding]; other site
1035817004323	dimer interface [polypeptide binding]; other site
1035817004324	TPP binding site [chemical binding]; other site
1035817004325	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1035817004326	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817004327	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817004328	FtsX-like permease family; Region: FtsX; pfam02687
1035817004329	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817004330	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817004331	Walker A/P-loop; other site
1035817004332	ATP binding site [chemical binding]; other site
1035817004333	Q-loop/lid; other site
1035817004334	ABC transporter signature motif; other site
1035817004335	Walker B; other site
1035817004336	D-loop; other site
1035817004337	H-loop/switch region; other site
1035817004338	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1035817004339	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1035817004340	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1035817004341	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1035817004342	putative active site [active]
1035817004343	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1035817004344	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1035817004345	transmembrane helices; other site
1035817004346	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1035817004347	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1035817004348	catalytic nucleophile [active]
1035817004349	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1035817004350	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1035817004351	DNA-binding site [nucleotide binding]; DNA binding site
1035817004352	Rhoptry-associated protein 1 (RAP-1); Region: RAP1; pfam07218
1035817004353	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1035817004354	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817004355	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817004356	homodimer interface [polypeptide binding]; other site
1035817004357	catalytic residue [active]
1035817004358	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13152
1035817004359	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1035817004360	predicted active site [active]
1035817004361	catalytic triad [active]
1035817004362	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1035817004363	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1035817004364	active site
1035817004365	multimer interface [polypeptide binding]; other site
1035817004366	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1035817004367	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817004368	non-specific DNA binding site [nucleotide binding]; other site
1035817004369	salt bridge; other site
1035817004370	sequence-specific DNA binding site [nucleotide binding]; other site
1035817004371	DNA primase; Validated; Region: dnaG; PRK05667
1035817004372	CHC2 zinc finger; Region: zf-CHC2; cl17510
1035817004373	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1035817004374	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1035817004375	active site
1035817004376	metal binding site [ion binding]; metal-binding site
1035817004377	interdomain interaction site; other site
1035817004378	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1035817004379	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK03007
1035817004380	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1035817004381	Zn2+ binding site [ion binding]; other site
1035817004382	Mg2+ binding site [ion binding]; other site
1035817004383	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1035817004384	alanine racemase; Reviewed; Region: alr; PRK00053
1035817004385	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1035817004386	active site
1035817004387	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1035817004388	dimer interface [polypeptide binding]; other site
1035817004389	substrate binding site [chemical binding]; other site
1035817004390	catalytic residues [active]
1035817004391	amino acid transporter; Region: 2A0306; TIGR00909
1035817004392	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1035817004393	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1035817004394	Helix-turn-helix domain; Region: HTH_38; pfam13936
1035817004395	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817004396	Integrase core domain; Region: rve; pfam00665
1035817004397	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
1035817004398	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1035817004399	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1035817004400	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1035817004401	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817004402	ATP binding site [chemical binding]; other site
1035817004403	putative Mg++ binding site [ion binding]; other site
1035817004404	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817004405	nucleotide binding region [chemical binding]; other site
1035817004406	ATP-binding site [chemical binding]; other site
1035817004407	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1035817004408	HRDC domain; Region: HRDC; pfam00570
1035817004409	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1035817004410	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1035817004411	cystathionine gamma-synthase; Provisional; Region: PRK07811
1035817004412	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1035817004413	homodimer interface [polypeptide binding]; other site
1035817004414	substrate-cofactor binding pocket; other site
1035817004415	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817004416	catalytic residue [active]
1035817004417	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1035817004418	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1035817004419	dimer interface [polypeptide binding]; other site
1035817004420	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817004421	catalytic residue [active]
1035817004422	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1035817004423	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817004424	Walker A/P-loop; other site
1035817004425	ATP binding site [chemical binding]; other site
1035817004426	Q-loop/lid; other site
1035817004427	ABC transporter signature motif; other site
1035817004428	Walker B; other site
1035817004429	D-loop; other site
1035817004430	H-loop/switch region; other site
1035817004431	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1035817004432	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1035817004433	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1035817004434	Walker A/P-loop; other site
1035817004435	ATP binding site [chemical binding]; other site
1035817004436	Q-loop/lid; other site
1035817004437	ABC transporter signature motif; other site
1035817004438	Walker B; other site
1035817004439	D-loop; other site
1035817004440	H-loop/switch region; other site
1035817004441	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1035817004442	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004443	ABC-ATPase subunit interface; other site
1035817004444	putative PBP binding loops; other site
1035817004445	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1035817004446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004447	putative PBP binding loops; other site
1035817004448	dimer interface [polypeptide binding]; other site
1035817004449	ABC-ATPase subunit interface; other site
1035817004450	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1035817004451	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_6; cd08494
1035817004452	pantothenate kinase; Reviewed; Region: PRK13318
1035817004453	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817004454	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817004455	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817004456	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817004457	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817004458	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817004459	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1035817004460	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1035817004461	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1035817004462	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817004463	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817004464	DNA binding site [nucleotide binding]
1035817004465	domain linker motif; other site
1035817004466	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817004467	ligand binding site [chemical binding]; other site
1035817004468	dimerization interface [polypeptide binding]; other site
1035817004469	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1035817004470	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1035817004471	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1035817004472	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817004473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004474	dimer interface [polypeptide binding]; other site
1035817004475	conserved gate region; other site
1035817004476	putative PBP binding loops; other site
1035817004477	ABC-ATPase subunit interface; other site
1035817004478	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004479	dimer interface [polypeptide binding]; other site
1035817004480	conserved gate region; other site
1035817004481	putative PBP binding loops; other site
1035817004482	ABC-ATPase subunit interface; other site
1035817004483	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817004484	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817004485	DNA binding site [nucleotide binding]
1035817004486	domain linker motif; other site
1035817004487	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1035817004488	ligand binding site [chemical binding]; other site
1035817004489	dimerization interface (open form) [polypeptide binding]; other site
1035817004490	dimerization interface (closed form) [polypeptide binding]; other site
1035817004491	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1035817004492	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817004493	non-specific DNA binding site [nucleotide binding]; other site
1035817004494	salt bridge; other site
1035817004495	sequence-specific DNA binding site [nucleotide binding]; other site
1035817004496	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1035817004497	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1035817004498	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1035817004499	active site
1035817004500	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1035817004501	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1035817004502	glutaminase active site [active]
1035817004503	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1035817004504	dimer interface [polypeptide binding]; other site
1035817004505	active site
1035817004506	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1035817004507	dimer interface [polypeptide binding]; other site
1035817004508	active site
1035817004509	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1035817004510	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1035817004511	Walker A/P-loop; other site
1035817004512	ATP binding site [chemical binding]; other site
1035817004513	Q-loop/lid; other site
1035817004514	ABC transporter signature motif; other site
1035817004515	Walker B; other site
1035817004516	D-loop; other site
1035817004517	H-loop/switch region; other site
1035817004518	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004519	dimer interface [polypeptide binding]; other site
1035817004520	conserved gate region; other site
1035817004521	ABC-ATPase subunit interface; other site
1035817004522	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817004523	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1035817004524	substrate binding pocket [chemical binding]; other site
1035817004525	membrane-bound complex binding site; other site
1035817004526	hinge residues; other site
1035817004527	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1035817004528	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1035817004529	substrate binding pocket [chemical binding]; other site
1035817004530	membrane-bound complex binding site; other site
1035817004531	hinge residues; other site
1035817004532	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1035817004533	SmpB-tmRNA interface; other site
1035817004534	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1035817004535	FtsX-like permease family; Region: FtsX; pfam02687
1035817004536	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1035817004537	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004538	Walker A/P-loop; other site
1035817004539	ATP binding site [chemical binding]; other site
1035817004540	Q-loop/lid; other site
1035817004541	ABC transporter signature motif; other site
1035817004542	Walker B; other site
1035817004543	D-loop; other site
1035817004544	H-loop/switch region; other site
1035817004545	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1035817004546	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1035817004547	RF-1 domain; Region: RF-1; pfam00472
1035817004548	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1035817004549	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1035817004550	active site
1035817004551	substrate binding site [chemical binding]; other site
1035817004552	catalytic site [active]
1035817004553	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1035817004554	active site
1035817004555	catalytic residues [active]
1035817004556	metal binding site [ion binding]; metal-binding site
1035817004557	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14318
1035817004558	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1035817004559	active site
1035817004560	substrate binding site [chemical binding]; other site
1035817004561	metal binding site [ion binding]; metal-binding site
1035817004562	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1035817004563	aminopeptidase N, Streptomyces lividans type; Region: pepN_strep_liv; TIGR02412
1035817004564	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_3; cd09602
1035817004565	Zn binding site [ion binding]; other site
1035817004566	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1035817004567	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1035817004568	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1035817004569	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1035817004570	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1035817004571	dimer interface [polypeptide binding]; other site
1035817004572	active site
1035817004573	catalytic residue [active]
1035817004574	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1035817004575	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1035817004576	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1035817004577	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817004578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817004579	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
1035817004580	Family description; Region: UvrD_C_2; pfam13538
1035817004581	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1035817004582	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1035817004583	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1035817004584	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817004585	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1035817004586	active site
1035817004587	ATP binding site [chemical binding]; other site
1035817004588	substrate binding site [chemical binding]; other site
1035817004589	activation loop (A-loop); other site
1035817004590	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1035817004591	Interdomain contacts; other site
1035817004592	Cytokine receptor motif; other site
1035817004593	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1035817004594	Interdomain contacts; other site
1035817004595	Cytokine receptor motif; other site
1035817004596	MoxR-like ATPases [General function prediction only]; Region: COG0714
1035817004597	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817004598	Walker A motif; other site
1035817004599	ATP binding site [chemical binding]; other site
1035817004600	Walker B motif; other site
1035817004601	arginine finger; other site
1035817004602	Protein of unknown function (DUF3093); Region: DUF3093; pfam11292
1035817004603	Protein of unknown function DUF58; Region: DUF58; pfam01882
1035817004604	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1035817004605	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1035817004606	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
1035817004607	active site
1035817004608	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1035817004609	phosphopeptide binding site; other site
1035817004610	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1035817004611	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1035817004612	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1035817004613	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1035817004614	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1035817004615	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1035817004616	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1035817004617	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1035817004618	DNA binding site [nucleotide binding]
1035817004619	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1035817004620	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1035817004621	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1035817004622	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1035817004623	RPB1 interaction site [polypeptide binding]; other site
1035817004624	RPB10 interaction site [polypeptide binding]; other site
1035817004625	RPB11 interaction site [polypeptide binding]; other site
1035817004626	RPB3 interaction site [polypeptide binding]; other site
1035817004627	RPB12 interaction site [polypeptide binding]; other site
1035817004628	Alphaherpesvirus tegument protein US9; Region: Herpes_US9; pfam06072
1035817004629	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1035817004630	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1035817004631	minor groove reading motif; other site
1035817004632	helix-hairpin-helix signature motif; other site
1035817004633	active site
1035817004634	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1035817004635	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1035817004636	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
1035817004637	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
1035817004638	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1035817004639	galactokinase; Provisional; Region: PRK05322
1035817004640	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1035817004641	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1035817004642	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
1035817004643	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1035817004644	dimer interface [polypeptide binding]; other site
1035817004645	active site
1035817004646	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1035817004647	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1035817004648	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1035817004649	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1035817004650	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1035817004651	quinone interaction residues [chemical binding]; other site
1035817004652	active site
1035817004653	catalytic residues [active]
1035817004654	FMN binding site [chemical binding]; other site
1035817004655	substrate binding site [chemical binding]; other site
1035817004656	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1035817004657	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1035817004658	active site
1035817004659	FMN binding site [chemical binding]; other site
1035817004660	substrate binding site [chemical binding]; other site
1035817004661	homotetramer interface [polypeptide binding]; other site
1035817004662	catalytic residue [active]
1035817004663	Transglycosylase; Region: Transgly; pfam00912
1035817004664	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1035817004665	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1035817004666	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1035817004667	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1035817004668	ligand binding site [chemical binding]; other site
1035817004669	flexible hinge region; other site
1035817004670	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1035817004671	putative switch regulator; other site
1035817004672	non-specific DNA interactions [nucleotide binding]; other site
1035817004673	DNA binding site [nucleotide binding]
1035817004674	sequence specific DNA binding site [nucleotide binding]; other site
1035817004675	putative cAMP binding site [chemical binding]; other site
1035817004676	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1035817004677	3-isopropylmalate dehydrogenase; Provisional; Region: PRK03437
1035817004678	tartrate dehydrogenase; Region: TTC; TIGR02089
1035817004679	Prolyl oligopeptidase, N-terminal beta-propeller domain; Region: Peptidase_S9_N; pfam02897
1035817004680	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1035817004681	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1035817004682	Uncharacterized conserved protein [Function unknown]; Region: COG4850
1035817004683	Uncharacterized conserved protein (DUF2183); Region: DUF2183; pfam09949
1035817004684	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1035817004685	lipoyl attachment site [posttranslational modification]; other site
1035817004686	NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]; Region: NPY1; COG2816
1035817004687	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1035817004688	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1035817004689	putative NADH binding site [chemical binding]; other site
1035817004690	putative active site [active]
1035817004691	nudix motif; other site
1035817004692	putative metal binding site [ion binding]; other site
1035817004693	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1035817004694	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1035817004695	nudix motif; other site
1035817004696	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1035817004697	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1035817004698	catalytic residues [active]
1035817004699	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1035817004700	G5 domain; Region: G5; pfam07501
1035817004701	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1035817004702	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1035817004703	catalytic residue [active]
1035817004704	Chain length determinant protein; Region: Wzz; cl15801
1035817004705	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1035817004706	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1035817004707	Nucleotide binding site [chemical binding]; other site
1035817004708	DTAP/Switch II; other site
1035817004709	Switch I; other site
1035817004710	AAA domain; Region: AAA_21; pfam13304
1035817004711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004712	Walker B; other site
1035817004713	D-loop; other site
1035817004714	H-loop/switch region; other site
1035817004715	RloB-like protein; Region: RloB; pfam13707
1035817004716	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1035817004717	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817004718	MULE transposase domain; Region: MULE; pfam10551
1035817004719	HTH-like domain; Region: HTH_21; pfam13276
1035817004720	Integrase core domain; Region: rve; pfam00665
1035817004721	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817004722	MULE transposase domain; Region: MULE; pfam10551
1035817004723	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1035817004724	Integrase core domain; Region: rve; pfam00665
1035817004725	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817004726	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1035817004727	Walker A motif; other site
1035817004728	ATP binding site [chemical binding]; other site
1035817004729	Walker B motif; other site
1035817004730	arginine finger; other site
1035817004731	Integrase core domain; Region: rve; pfam00665
1035817004732	Integrase core domain; Region: rve_2; pfam13333
1035817004733	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
1035817004734	FMN binding site [chemical binding]; other site
1035817004735	dimer interface [polypeptide binding]; other site
1035817004736	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1035817004737	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1035817004738	trimer interface [polypeptide binding]; other site
1035817004739	CoA binding site [chemical binding]; other site
1035817004740	active site
1035817004741	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1035817004742	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1035817004743	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
1035817004744	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
1035817004745	putative ADP-binding pocket [chemical binding]; other site
1035817004746	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1035817004747	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1035817004748	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1035817004749	active site
1035817004750	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1035817004751	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1035817004752	active site
1035817004753	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1035817004754	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1035817004755	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
1035817004756	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817004757	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1035817004758	putative substrate translocation pore; other site
1035817004759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817004760	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817004761	Integrase core domain; Region: rve; pfam00665
1035817004762	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
1035817004763	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1035817004764	AAA domain; Region: AAA_14; pfam13173
1035817004765	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1035817004766	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1035817004767	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817004768	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817004769	active site
1035817004770	catalytic tetrad [active]
1035817004771	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1035817004772	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1035817004773	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1035817004774	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817004775	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817004776	DNA binding site [nucleotide binding]
1035817004777	domain linker motif; other site
1035817004778	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817004779	ligand binding site [chemical binding]; other site
1035817004780	dimerization interface [polypeptide binding]; other site
1035817004781	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1035817004782	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1035817004783	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1035817004784	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817004785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004786	dimer interface [polypeptide binding]; other site
1035817004787	conserved gate region; other site
1035817004788	putative PBP binding loops; other site
1035817004789	ABC-ATPase subunit interface; other site
1035817004790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004791	dimer interface [polypeptide binding]; other site
1035817004792	conserved gate region; other site
1035817004793	putative PBP binding loops; other site
1035817004794	ABC-ATPase subunit interface; other site
1035817004795	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817004796	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817004797	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1035817004798	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817004799	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1035817004800	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004801	Walker A/P-loop; other site
1035817004802	ATP binding site [chemical binding]; other site
1035817004803	Q-loop/lid; other site
1035817004804	ABC transporter signature motif; other site
1035817004805	Walker B; other site
1035817004806	D-loop; other site
1035817004807	H-loop/switch region; other site
1035817004808	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1035817004809	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1035817004810	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817004811	Walker A/P-loop; other site
1035817004812	ATP binding site [chemical binding]; other site
1035817004813	Q-loop/lid; other site
1035817004814	ABC transporter signature motif; other site
1035817004815	Walker B; other site
1035817004816	D-loop; other site
1035817004817	H-loop/switch region; other site
1035817004818	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1035817004819	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1035817004820	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1035817004821	acyl-activating enzyme (AAE) consensus motif; other site
1035817004822	putative AMP binding site [chemical binding]; other site
1035817004823	putative active site [active]
1035817004824	putative CoA binding site [chemical binding]; other site
1035817004825	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817004826	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817004827	Walker A/P-loop; other site
1035817004828	ATP binding site [chemical binding]; other site
1035817004829	Q-loop/lid; other site
1035817004830	ABC transporter signature motif; other site
1035817004831	Walker B; other site
1035817004832	D-loop; other site
1035817004833	H-loop/switch region; other site
1035817004834	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817004835	FtsX-like permease family; Region: FtsX; pfam02687
1035817004836	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817004837	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817004838	FtsX-like permease family; Region: FtsX; pfam02687
1035817004839	Peptidase C26; Region: Peptidase_C26; pfam07722
1035817004840	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1035817004841	catalytic triad [active]
1035817004842	L-arabinose isomerase; Provisional; Region: PRK02929
1035817004843	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1035817004844	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1035817004845	trimer interface [polypeptide binding]; other site
1035817004846	substrate binding site [chemical binding]; other site
1035817004847	Mn binding site [ion binding]; other site
1035817004848	L-ribulose-5-phosphate 4-epimerase; Validated; Region: PRK06557
1035817004849	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1035817004850	intersubunit interface [polypeptide binding]; other site
1035817004851	active site
1035817004852	Zn2+ binding site [ion binding]; other site
1035817004853	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
1035817004854	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1035817004855	putative N- and C-terminal domain interface [polypeptide binding]; other site
1035817004856	putative active site [active]
1035817004857	MgATP binding site [chemical binding]; other site
1035817004858	catalytic site [active]
1035817004859	metal binding site [ion binding]; metal-binding site
1035817004860	putative carbohydrate binding site [chemical binding]; other site
1035817004861	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817004862	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817004863	DNA binding site [nucleotide binding]
1035817004864	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1035817004865	ligand binding site [chemical binding]; other site
1035817004866	dimerization interface (open form) [polypeptide binding]; other site
1035817004867	dimerization interface (closed form) [polypeptide binding]; other site
1035817004868	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1035817004869	RNA/DNA hybrid binding site [nucleotide binding]; other site
1035817004870	active site
1035817004871	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1035817004872	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1035817004873	Catalytic site [active]
1035817004874	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1035817004875	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1035817004876	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1035817004877	active site
1035817004878	dimer interface [polypeptide binding]; other site
1035817004879	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1035817004880	dimer interface [polypeptide binding]; other site
1035817004881	active site
1035817004882	Membrane transport protein; Region: Mem_trans; cl09117
1035817004883	FemAB family; Region: FemAB; pfam02388
1035817004884	FemAB family; Region: FemAB; pfam02388
1035817004885	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
1035817004886	FemAB family; Region: FemAB; pfam02388
1035817004887	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1035817004888	active site
1035817004889	dimerization interface [polypeptide binding]; other site
1035817004890	ribonuclease PH; Reviewed; Region: rph; PRK00173
1035817004891	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1035817004892	hexamer interface [polypeptide binding]; other site
1035817004893	active site
1035817004894	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1035817004895	Helix-turn-helix domain; Region: HTH_38; pfam13936
1035817004896	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817004897	Integrase core domain; Region: rve; pfam00665
1035817004898	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1035817004899	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1035817004900	active site
1035817004901	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1035817004902	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1035817004903	DNA binding residues [nucleotide binding]
1035817004904	putative dimer interface [polypeptide binding]; other site
1035817004905	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817004906	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817004907	active site
1035817004908	catalytic tetrad [active]
1035817004909	Protein of unknown function (DUF3039); Region: DUF3039; pfam11238
1035817004910	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1035817004911	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1035817004912	active site
1035817004913	(T/H)XGH motif; other site
1035817004914	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1035817004915	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1035817004916	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1035817004917	ribonuclease III; Reviewed; Region: rnc; PRK00102
1035817004918	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1035817004919	dimerization interface [polypeptide binding]; other site
1035817004920	active site
1035817004921	metal binding site [ion binding]; metal-binding site
1035817004922	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1035817004923	dsRNA binding site [nucleotide binding]; other site
1035817004924	acetolactate synthase 1 catalytic subunit; Validated; Region: PRK07789
1035817004925	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1035817004926	PYR/PP interface [polypeptide binding]; other site
1035817004927	dimer interface [polypeptide binding]; other site
1035817004928	TPP binding site [chemical binding]; other site
1035817004929	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1035817004930	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1035817004931	TPP-binding site [chemical binding]; other site
1035817004932	dimer interface [polypeptide binding]; other site
1035817004933	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1035817004934	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1035817004935	putative valine binding site [chemical binding]; other site
1035817004936	dimer interface [polypeptide binding]; other site
1035817004937	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1035817004938	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
1035817004939	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1035817004940	oligomeric interface; other site
1035817004941	putative active site [active]
1035817004942	homodimer interface [polypeptide binding]; other site
1035817004943	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817004944	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1035817004945	ABC transporter; Region: ABC_tran_2; pfam12848
1035817004946	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817004947	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1035817004948	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1035817004949	catalytic triad [active]
1035817004950	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1035817004951	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1035817004952	active site
1035817004953	HIGH motif; other site
1035817004954	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1035817004955	KMSKS motif; other site
1035817004956	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1035817004957	tRNA binding surface [nucleotide binding]; other site
1035817004958	anticodon binding site; other site
1035817004959	Cation efflux family; Region: Cation_efflux; pfam01545
1035817004960	signal recognition particle protein; Provisional; Region: PRK10867
1035817004961	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1035817004962	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1035817004963	P loop; other site
1035817004964	GTP binding site [chemical binding]; other site
1035817004965	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1035817004966	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1035817004967	putative catalytic site [active]
1035817004968	putative metal binding site [ion binding]; other site
1035817004969	putative phosphate binding site [ion binding]; other site
1035817004970	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14520
1035817004971	hypothetical protein; Provisional; Region: PRK02821
1035817004972	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1035817004973	G-X-X-G motif; other site
1035817004974	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1035817004975	RimM N-terminal domain; Region: RimM; pfam01782
1035817004976	NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These...; Region: nuc_hydro_CaPnhB; cd02650
1035817004977	active site
1035817004978	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1035817004979	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1035817004980	active site
1035817004981	catalytic tetrad [active]
1035817004982	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
1035817004983	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1035817004984	phosphate transporter ATP-binding protein; Provisional; Region: PRK14241
1035817004985	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1035817004986	Walker A/P-loop; other site
1035817004987	ATP binding site [chemical binding]; other site
1035817004988	Q-loop/lid; other site
1035817004989	ABC transporter signature motif; other site
1035817004990	Walker B; other site
1035817004991	D-loop; other site
1035817004992	H-loop/switch region; other site
1035817004993	sulfate transport protein; Provisional; Region: cysT; CHL00187
1035817004994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817004995	dimer interface [polypeptide binding]; other site
1035817004996	conserved gate region; other site
1035817004997	putative PBP binding loops; other site
1035817004998	ABC-ATPase subunit interface; other site
1035817004999	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
1035817005000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005001	dimer interface [polypeptide binding]; other site
1035817005002	conserved gate region; other site
1035817005003	putative PBP binding loops; other site
1035817005004	ABC-ATPase subunit interface; other site
1035817005005	PBP superfamily domain; Region: PBP_like_2; cl17296
1035817005006	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817005007	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817005008	active site
1035817005009	phosphorylation site [posttranslational modification]
1035817005010	intermolecular recognition site; other site
1035817005011	dimerization interface [polypeptide binding]; other site
1035817005012	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1035817005013	DNA binding site [nucleotide binding]
1035817005014	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1035817005015	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1035817005016	dimer interface [polypeptide binding]; other site
1035817005017	phosphorylation site [posttranslational modification]
1035817005018	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817005019	ATP binding site [chemical binding]; other site
1035817005020	Mg2+ binding site [ion binding]; other site
1035817005021	G-X-G motif; other site
1035817005022	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1035817005023	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1035817005024	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1035817005025	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1035817005026	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1035817005027	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1035817005028	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1035817005029	trimer interface [polypeptide binding]; other site
1035817005030	active site
1035817005031	G bulge; other site
1035817005032	DivIVA protein; Region: DivIVA; pfam05103
1035817005033	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1035817005034	putative substrate binding pocket [chemical binding]; other site
1035817005035	AC domain interface; other site
1035817005036	catalytic triad [active]
1035817005037	AB domain interface; other site
1035817005038	interchain disulfide; other site
1035817005039	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1035817005040	substrate binding site; other site
1035817005041	dimer interface; other site
1035817005042	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1035817005043	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1035817005044	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1035817005045	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1035817005046	Peptidase family U32; Region: Peptidase_U32; pfam01136
1035817005047	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1035817005048	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1035817005049	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1035817005050	S-adenosylmethionine binding site [chemical binding]; other site
1035817005051	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1035817005052	ssDNA binding site; other site
1035817005053	generic binding surface II; other site
1035817005054	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1035817005055	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817005056	ATP binding site [chemical binding]; other site
1035817005057	putative Mg++ binding site [ion binding]; other site
1035817005058	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817005059	nucleotide binding region [chemical binding]; other site
1035817005060	ATP-binding site [chemical binding]; other site
1035817005061	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1035817005062	YegV-like sugar kinase.  Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944
1035817005063	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1035817005064	substrate binding site [chemical binding]; other site
1035817005065	ATP binding site [chemical binding]; other site
1035817005066	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
1035817005067	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817005068	putative substrate translocation pore; other site
1035817005069	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1035817005070	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1035817005071	DNA binding site [nucleotide binding]
1035817005072	active site
1035817005073	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
1035817005074	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1035817005075	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817005076	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817005077	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1035817005078	Aspartase; Region: Aspartase; cd01357
1035817005079	active sites [active]
1035817005080	tetramer interface [polypeptide binding]; other site
1035817005081	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1035817005082	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1035817005083	CAAX protease self-immunity; Region: Abi; pfam02517
1035817005084	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1035817005085	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817005086	Walker A/P-loop; other site
1035817005087	ATP binding site [chemical binding]; other site
1035817005088	Q-loop/lid; other site
1035817005089	ABC transporter signature motif; other site
1035817005090	Walker B; other site
1035817005091	D-loop; other site
1035817005092	H-loop/switch region; other site
1035817005093	TOBE domain; Region: TOBE_2; pfam08402
1035817005094	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005095	dimer interface [polypeptide binding]; other site
1035817005096	conserved gate region; other site
1035817005097	putative PBP binding loops; other site
1035817005098	ABC-ATPase subunit interface; other site
1035817005099	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1035817005100	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817005101	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1035817005102	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1035817005103	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1035817005104	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1035817005105	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1035817005106	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1035817005107	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1035817005108	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1035817005109	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1035817005110	putative acyl-acceptor binding pocket; other site
1035817005111	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1035817005112	homotrimer interaction site [polypeptide binding]; other site
1035817005113	putative active site [active]
1035817005114	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
1035817005115	putative active site [active]
1035817005116	putative metal binding residues [ion binding]; other site
1035817005117	signature motif; other site
1035817005118	putative dimer interface [polypeptide binding]; other site
1035817005119	putative phosphate binding site [ion binding]; other site
1035817005120	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1035817005121	Integrase core domain; Region: rve; pfam00665
1035817005122	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1035817005123	hypothetical protein; Provisional; Region: PRK03298
1035817005124	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1035817005125	gamma subunit interface [polypeptide binding]; other site
1035817005126	epsilon subunit interface [polypeptide binding]; other site
1035817005127	LBP interface [polypeptide binding]; other site
1035817005128	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1035817005129	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1035817005130	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1035817005131	alpha subunit interaction interface [polypeptide binding]; other site
1035817005132	Walker A motif; other site
1035817005133	ATP binding site [chemical binding]; other site
1035817005134	Walker B motif; other site
1035817005135	inhibitor binding site; inhibition site
1035817005136	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1035817005137	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1035817005138	core domain interface [polypeptide binding]; other site
1035817005139	delta subunit interface [polypeptide binding]; other site
1035817005140	epsilon subunit interface [polypeptide binding]; other site
1035817005141	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1035817005142	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1035817005143	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1035817005144	beta subunit interaction interface [polypeptide binding]; other site
1035817005145	Walker A motif; other site
1035817005146	ATP binding site [chemical binding]; other site
1035817005147	Walker B motif; other site
1035817005148	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1035817005149	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13430
1035817005150	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1035817005151	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1035817005152	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1035817005153	ATP synthase subunit C; Region: ATP-synt_C; cl00466
1035817005154	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1035817005155	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1035817005156	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1035817005157	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1035817005158	proposed active site lysine [active]
1035817005159	conserved cys residue [active]
1035817005160	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
1035817005161	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
1035817005162	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1035817005163	active site
1035817005164	homodimer interface [polypeptide binding]; other site
1035817005165	catalytic site [active]
1035817005166	acceptor binding site [chemical binding]; other site
1035817005167	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1035817005168	dimer interface [polypeptide binding]; other site
1035817005169	substrate binding site [chemical binding]; other site
1035817005170	metal binding sites [ion binding]; metal-binding site
1035817005171	Predicted membrane protein [Function unknown]; Region: COG1971
1035817005172	Domain of unknown function DUF; Region: DUF204; pfam02659
1035817005173	Domain of unknown function DUF; Region: DUF204; pfam02659
1035817005174	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1035817005175	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1035817005176	DNA binding site [nucleotide binding]
1035817005177	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1035817005178	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1035817005179	minor groove reading motif; other site
1035817005180	helix-hairpin-helix signature motif; other site
1035817005181	substrate binding pocket [chemical binding]; other site
1035817005182	active site
1035817005183	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1035817005184	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_6; cd08494
1035817005185	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1035817005186	valyl-tRNA synthetase; Reviewed; Region: valS; PRK13208
1035817005187	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817005188	active site
1035817005189	HIGH motif; other site
1035817005190	nucleotide binding site [chemical binding]; other site
1035817005191	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1035817005192	active site
1035817005193	KMSKS motif; other site
1035817005194	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1035817005195	tRNA binding surface [nucleotide binding]; other site
1035817005196	anticodon binding site; other site
1035817005197	monofunctional chorismate mutase, alpha proteobacterial type; Region: CM_mono_cladeE; TIGR01795
1035817005198	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1035817005199	transcription termination factor Rho; Provisional; Region: PRK12608
1035817005200	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1035817005201	RNA binding site [nucleotide binding]; other site
1035817005202	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1035817005203	multimer interface [polypeptide binding]; other site
1035817005204	Walker A motif; other site
1035817005205	ATP binding site [chemical binding]; other site
1035817005206	Walker B motif; other site
1035817005207	hypothetical protein; Provisional; Region: PRK07208
1035817005208	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1035817005209	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
1035817005210	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399
1035817005211	Protein of unknown function (DUF2469); Region: DUF2469; pfam10611
1035817005212	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1035817005213	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1035817005214	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1035817005215	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1035817005216	GatB domain; Region: GatB_Yqey; pfam02637
1035817005217	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1035817005218	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1035817005219	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1035817005220	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1035817005221	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1035817005222	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
1035817005223	RmuC family; Region: RmuC; pfam02646
1035817005224	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
1035817005225	putative homodimer interface [polypeptide binding]; other site
1035817005226	putative homotetramer interface [polypeptide binding]; other site
1035817005227	putative allosteric switch controlling residues; other site
1035817005228	putative metal binding site [ion binding]; other site
1035817005229	putative homodimer-homodimer interface [polypeptide binding]; other site
1035817005230	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1035817005231	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
1035817005232	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1035817005233	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817005234	active site
1035817005235	motif I; other site
1035817005236	motif II; other site
1035817005237	Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; Region: Ribosomal_L24e_L24; cl00909
1035817005238	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1035817005239	amphipathic channel; other site
1035817005240	Asn-Pro-Ala signature motifs; other site
1035817005241	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1035817005242	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1035817005243	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1035817005244	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1035817005245	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1035817005246	dimerization domain swap beta strand [polypeptide binding]; other site
1035817005247	regulatory protein interface [polypeptide binding]; other site
1035817005248	active site
1035817005249	regulatory phosphorylation site [posttranslational modification]; other site
1035817005250	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1035817005251	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1035817005252	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1035817005253	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1035817005254	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1035817005255	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1035817005256	dimer interface [polypeptide binding]; other site
1035817005257	ssDNA binding site [nucleotide binding]; other site
1035817005258	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1035817005259	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1035817005260	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1035817005261	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK03092
1035817005262	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1035817005263	active site
1035817005264	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1035817005265	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1035817005266	catalytic residue [active]
1035817005267	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
1035817005268	substrate binding site [chemical binding]; other site
1035817005269	active site
1035817005270	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1035817005271	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1035817005272	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
1035817005273	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
1035817005274	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1035817005275	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1035817005276	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817005277	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005278	dimer interface [polypeptide binding]; other site
1035817005279	conserved gate region; other site
1035817005280	putative PBP binding loops; other site
1035817005281	ABC-ATPase subunit interface; other site
1035817005282	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005283	dimer interface [polypeptide binding]; other site
1035817005284	conserved gate region; other site
1035817005285	putative PBP binding loops; other site
1035817005286	ABC-ATPase subunit interface; other site
1035817005287	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817005288	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817005289	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005290	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005291	DNA binding site [nucleotide binding]
1035817005292	domain linker motif; other site
1035817005293	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005294	dimerization interface [polypeptide binding]; other site
1035817005295	ligand binding site [chemical binding]; other site
1035817005296	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1035817005297	ABC1 family; Region: ABC1; cl17513
1035817005298	Nucleotidyl transferase of unknown function (DUF2204); Region: DUF2204; cl17690
1035817005299	Uncharacterized conserved protein [Function unknown]; Region: COG3937
1035817005300	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1035817005301	catalytic triad [active]
1035817005302	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
1035817005303	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1035817005304	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
1035817005305	replicative DNA helicase; Region: DnaB; TIGR00665
1035817005306	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1035817005307	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1035817005308	Walker A motif; other site
1035817005309	ATP binding site [chemical binding]; other site
1035817005310	Walker B motif; other site
1035817005311	DNA binding loops [nucleotide binding]
1035817005312	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1035817005313	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1035817005314	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1035817005315	metal binding triad; other site
1035817005316	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1035817005317	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; smart00471
1035817005318	Nitrogen regulatory protein P-II; Region: P-II; pfam00543
1035817005319	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1035817005320	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1035817005321	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1035817005322	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1035817005323	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1035817005324	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817005325	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817005326	putative glycosyl transferase; Provisional; Region: PRK10073
1035817005327	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1035817005328	active site
1035817005329	Peptidase family C69; Region: Peptidase_C69; pfam03577
1035817005330	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1035817005331	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1035817005332	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1035817005333	glucose-6-phosphate dehydrogenase assembly protein OpcA; Region: OpcA; TIGR00534
1035817005334	Glucose-6-phosphate dehydrogenase subunit; Region: OpcA_G6PD_assem; pfam10128
1035817005335	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1035817005336	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
1035817005337	putative active site [active]
1035817005338	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1035817005339	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1035817005340	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1035817005341	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
1035817005342	Predicted membrane protein [Function unknown]; Region: COG1511
1035817005343	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1035817005344	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1035817005345	Predicted membrane protein [Function unknown]; Region: COG1511
1035817005346	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1035817005347	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1035817005348	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817005349	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817005350	FMN-binding domain; Region: FMN_bind; cl01081
1035817005351	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1035817005352	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1035817005353	Walker A/P-loop; other site
1035817005354	ATP binding site [chemical binding]; other site
1035817005355	Q-loop/lid; other site
1035817005356	ABC transporter signature motif; other site
1035817005357	Walker B; other site
1035817005358	D-loop; other site
1035817005359	H-loop/switch region; other site
1035817005360	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1035817005361	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1035817005362	FtsX-like permease family; Region: FtsX; pfam02687
1035817005363	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1035817005364	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1035817005365	FtsX-like permease family; Region: FtsX; pfam02687
1035817005366	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
1035817005367	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
1035817005368	Fe2+ transport protein; Region: Iron_transport; pfam10634
1035817005369	Iron permease FTR1 family; Region: FTR1; cl00475
1035817005370	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1035817005371	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1035817005372	Endo-alpha-N-acetylgalactosaminidase; Region: Glyco_hydro_101; pfam12905
1035817005373	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1035817005374	sugar binding site [chemical binding]; other site
1035817005375	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1035817005376	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1035817005377	HIGH motif; other site
1035817005378	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1035817005379	active site
1035817005380	KMSKS motif; other site
1035817005381	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
1035817005382	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1035817005383	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1035817005384	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1035817005385	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1035817005386	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1035817005387	Abi-like protein; Region: Abi_2; pfam07751
1035817005388	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1035817005389	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1035817005390	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817005391	ATP binding site [chemical binding]; other site
1035817005392	putative Mg++ binding site [ion binding]; other site
1035817005393	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1035817005394	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1035817005395	active site
1035817005396	phosphate binding residues; other site
1035817005397	catalytic residues [active]
1035817005398	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1035817005399	catalytic core [active]
1035817005400	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817005401	Predicted membrane protein [Function unknown]; Region: COG2246
1035817005402	GtrA-like protein; Region: GtrA; pfam04138
1035817005403	macrophage migration inhibitory factor-like protein; Provisional; Region: PTZ00450
1035817005404	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1035817005405	Formyltetrahydrofolate synthetase [Nucleotide transport and metabolism]; Region: MIS1; COG2759
1035817005406	Peptidase family C69; Region: Peptidase_C69; pfam03577
1035817005407	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1035817005408	substrate binding site [chemical binding]; other site
1035817005409	DNA polymerase III subunit delta'; Validated; Region: PRK07940
1035817005410	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817005411	Walker A motif; other site
1035817005412	ATP binding site [chemical binding]; other site
1035817005413	Walker B motif; other site
1035817005414	thymidylate kinase; Validated; Region: tmk; PRK00698
1035817005415	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1035817005416	TMP-binding site; other site
1035817005417	ATP-binding site [chemical binding]; other site
1035817005418	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1035817005419	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1035817005420	active site
1035817005421	interdomain interaction site; other site
1035817005422	putative metal-binding site [ion binding]; other site
1035817005423	nucleotide binding site [chemical binding]; other site
1035817005424	Bacterial DNA topoisomeraes I ATP-binding domain; Region: TOP1Bc; smart00436
1035817005425	domain I; other site
1035817005426	phosphate binding site [ion binding]; other site
1035817005427	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1035817005428	domain II; other site
1035817005429	domain III; other site
1035817005430	nucleotide binding site [chemical binding]; other site
1035817005431	DNA binding groove [nucleotide binding]
1035817005432	catalytic site [active]
1035817005433	domain IV; other site
1035817005434	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1035817005435	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1035817005436	active site
1035817005437	Transglycosylase; Region: Transgly; pfam00912
1035817005438	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1035817005439	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1035817005440	2-isopropylmalate synthase; Validated; Region: PRK03739
1035817005441	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
1035817005442	active site
1035817005443	catalytic residues [active]
1035817005444	metal binding site [ion binding]; metal-binding site
1035817005445	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1035817005446	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1035817005447	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1035817005448	metal binding site [ion binding]; metal-binding site
1035817005449	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1035817005450	Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain; Region: MPP_Dcr2; cd07383
1035817005451	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
1035817005452	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1035817005453	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1035817005454	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1035817005455	putative allosteric regulatory site; other site
1035817005456	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1035817005457	aspartate kinase; Reviewed; Region: PRK06635
1035817005458	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1035817005459	putative nucleotide binding site [chemical binding]; other site
1035817005460	putative catalytic residues [active]
1035817005461	putative Mg ion binding site [ion binding]; other site
1035817005462	putative aspartate binding site [chemical binding]; other site
1035817005463	AAA domain; Region: AAA_14; pfam13173
1035817005464	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1035817005465	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
1035817005466	active site
1035817005467	catalytic site [active]
1035817005468	recombination protein RecR; Reviewed; Region: recR; PRK00076
1035817005469	RecR protein; Region: RecR; pfam02132
1035817005470	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1035817005471	putative active site [active]
1035817005472	putative metal-binding site [ion binding]; other site
1035817005473	tetramer interface [polypeptide binding]; other site
1035817005474	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1035817005475	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817005476	Walker A motif; other site
1035817005477	ATP binding site [chemical binding]; other site
1035817005478	Walker B motif; other site
1035817005479	arginine finger; other site
1035817005480	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1035817005481	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1035817005482	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1035817005483	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1035817005484	helicase/secretion neighborhood TadE-like protein; Region: tadE_like_DECH; TIGR03816
1035817005485	Protein of unknown function (DUF4244); Region: DUF4244; pfam14029
1035817005486	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1035817005487	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
1035817005488	ATP binding site [chemical binding]; other site
1035817005489	Walker B motif; other site
1035817005490	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1035817005491	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1035817005492	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005493	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005494	DNA binding site [nucleotide binding]
1035817005495	domain linker motif; other site
1035817005496	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005497	dimerization interface [polypeptide binding]; other site
1035817005498	ligand binding site [chemical binding]; other site
1035817005499	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817005500	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817005501	Glycosyl hydrolase family 43; Region: GH43_bXyl_2; cd08991
1035817005502	active site
1035817005503	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817005504	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005505	dimer interface [polypeptide binding]; other site
1035817005506	conserved gate region; other site
1035817005507	putative PBP binding loops; other site
1035817005508	ABC-ATPase subunit interface; other site
1035817005509	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1035817005510	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005511	dimer interface [polypeptide binding]; other site
1035817005512	conserved gate region; other site
1035817005513	putative PBP binding loops; other site
1035817005514	ABC-ATPase subunit interface; other site
1035817005515	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1035817005516	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1035817005517	motif II; other site
1035817005518	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08642
1035817005519	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1035817005520	NAD(P) binding site [chemical binding]; other site
1035817005521	active site
1035817005522	Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080
1035817005523	Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893
1035817005524	putative catalytic cysteine [active]
1035817005525	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
1035817005526	xanthine permease; Region: pbuX; TIGR03173
1035817005527	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1035817005528	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1035817005529	DNA binding residues [nucleotide binding]
1035817005530	putative dimer interface [polypeptide binding]; other site
1035817005531	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1035817005532	HSP70 interaction site [polypeptide binding]; other site
1035817005533	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1035817005534	substrate binding site [polypeptide binding]; other site
1035817005535	dimer interface [polypeptide binding]; other site
1035817005536	GrpE; Region: GrpE; pfam01025
1035817005537	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1035817005538	dimer interface [polypeptide binding]; other site
1035817005539	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1035817005540	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1035817005541	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817005542	nucleotide binding site [chemical binding]; other site
1035817005543	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1035817005544	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
1035817005545	putative active site [active]
1035817005546	putative catalytic site [active]
1035817005547	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817005548	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005549	ABC-ATPase subunit interface; other site
1035817005550	putative PBP binding loops; other site
1035817005551	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005552	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005553	DNA binding site [nucleotide binding]
1035817005554	domain linker motif; other site
1035817005555	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005556	ligand binding site [chemical binding]; other site
1035817005557	dimerization interface [polypeptide binding]; other site
1035817005558	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1035817005559	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1035817005560	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1035817005561	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1035817005562	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005563	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005564	DNA binding site [nucleotide binding]
1035817005565	domain linker motif; other site
1035817005566	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005567	ligand binding site [chemical binding]; other site
1035817005568	dimerization interface [polypeptide binding]; other site
1035817005569	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins; Region: AmyAc_OligoGlu_TS; cd11332
1035817005570	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1035817005571	active site
1035817005572	catalytic site [active]
1035817005573	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1035817005574	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1035817005575	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1035817005576	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1035817005577	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1035817005578	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1035817005579	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1035817005580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817005581	metabolite-proton symporter; Region: 2A0106; TIGR00883
1035817005582	putative substrate translocation pore; other site
1035817005583	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005584	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005585	DNA binding site [nucleotide binding]
1035817005586	domain linker motif; other site
1035817005587	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1035817005588	dimerization interface [polypeptide binding]; other site
1035817005589	ligand binding site [chemical binding]; other site
1035817005590	sodium binding site [ion binding]; other site
1035817005591	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817005592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817005593	sucrose phosphorylase; Provisional; Region: PRK13840
1035817005594	Alpha amylase catalytic domain found in sucrose phosphorylase (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase; cd11355
1035817005595	active site
1035817005596	homodimer interface [polypeptide binding]; other site
1035817005597	catalytic site [active]
1035817005598	Domain of unknown function (DUF1964); Region: DUF1964; pfam09244
1035817005599	Helix-turn-helix domain; Region: HTH_28; pfam13518
1035817005600	Winged helix-turn helix; Region: HTH_29; pfam13551
1035817005601	HTH-like domain; Region: HTH_21; pfam13276
1035817005602	Integrase core domain; Region: rve; pfam00665
1035817005603	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1035817005604	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817005605	pAE1 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal domain. This CD includes various bacterial integrases, including the predicted integrase of the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus...; Region: INT_pAE1; cd01188
1035817005606	Int/Topo IB signature motif; other site
1035817005607	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817005608	active site
1035817005609	DNA binding site [nucleotide binding]
1035817005610	Int/Topo IB signature motif; other site
1035817005611	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1035817005612	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1035817005613	active site
1035817005614	DNA binding site [nucleotide binding]
1035817005615	Int/Topo IB signature motif; other site
1035817005616	Integrase core domain; Region: rve_2; pfam13333
1035817005617	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
1035817005618	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005619	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005620	DNA binding site [nucleotide binding]
1035817005621	domain linker motif; other site
1035817005622	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005623	dimerization interface [polypeptide binding]; other site
1035817005624	ligand binding site [chemical binding]; other site
1035817005625	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1035817005626	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1035817005627	K+ potassium transporter; Region: K_trans; pfam02705
1035817005628	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005629	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005630	DNA binding site [nucleotide binding]
1035817005631	domain linker motif; other site
1035817005632	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1035817005633	dimerization interface [polypeptide binding]; other site
1035817005634	ligand binding site [chemical binding]; other site
1035817005635	sodium binding site [ion binding]; other site
1035817005636	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817005637	MULE transposase domain; Region: MULE; pfam10551
1035817005638	CrcB-like protein; Region: CRCB; pfam02537
1035817005639	CrcB-like protein; Region: CRCB; pfam02537
1035817005640	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1035817005641	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1035817005642	Cl- selectivity filter; other site
1035817005643	Cl- binding residues [ion binding]; other site
1035817005644	pore gating glutamate residue; other site
1035817005645	dimer interface [polypeptide binding]; other site
1035817005646	H+/Cl- coupling transport residue; other site
1035817005647	TrkA-C domain; Region: TrkA_C; pfam02080
1035817005648	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1035817005649	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1035817005650	GDP-binding site [chemical binding]; other site
1035817005651	ACT binding site; other site
1035817005652	IMP binding site; other site
1035817005653	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1035817005654	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
1035817005655	active site
1035817005656	intersubunit interface [polypeptide binding]; other site
1035817005657	zinc binding site [ion binding]; other site
1035817005658	Na+ binding site [ion binding]; other site
1035817005659	heat shock protein HtpX; Provisional; Region: PRK03072
1035817005660	ferredoxin-NADP+ reductase; Region: PLN02852
1035817005661	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1035817005662	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1035817005663	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
1035817005664	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1035817005665	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1035817005666	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
1035817005667	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1035817005668	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1035817005669	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; cl00409
1035817005670	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1035817005671	Haemolysin-III related; Region: HlyIII; pfam03006
1035817005672	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1035817005673	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1035817005674	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1035817005675	Coenzyme A binding pocket [chemical binding]; other site
1035817005676	hypothetical protein; Provisional; Region: PRK01119
1035817005677	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1035817005678	active site
1035817005679	8-oxo-dGMP binding site [chemical binding]; other site
1035817005680	nudix motif; other site
1035817005681	metal binding site [ion binding]; metal-binding site
1035817005682	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204
1035817005683	PLD-like domain; Region: PLDc_2; pfam13091
1035817005684	putative homodimer interface [polypeptide binding]; other site
1035817005685	putative active site [active]
1035817005686	catalytic site [active]
1035817005687	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1035817005688	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1035817005689	ATP binding site [chemical binding]; other site
1035817005690	putative Mg++ binding site [ion binding]; other site
1035817005691	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1035817005692	nucleotide binding region [chemical binding]; other site
1035817005693	ATP-binding site [chemical binding]; other site
1035817005694	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
1035817005695	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
1035817005696	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1035817005697	SelR domain; Region: SelR; pfam01641
1035817005698	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1035817005699	Putative esterase; Region: Esterase; pfam00756
1035817005700	aromatic amino acid exporter; Provisional; Region: PRK11689
1035817005701	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1035817005702	Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471
1035817005703	putative dimer interface [polypeptide binding]; other site
1035817005704	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1035817005705	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1035817005706	metal ion-dependent adhesion site (MIDAS); other site
1035817005707	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1035817005708	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1035817005709	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1035817005710	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1035817005711	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1035817005712	Protein of unknown function (DUF2662); Region: DUF3662; pfam12401
1035817005713	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1035817005714	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
1035817005715	phosphopeptide binding site; other site
1035817005716	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1035817005717	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
1035817005718	phosphopeptide binding site; other site
1035817005719	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1035817005720	active site
1035817005721	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1035817005722	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1035817005723	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1035817005724	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817005725	active site
1035817005726	ATP binding site [chemical binding]; other site
1035817005727	substrate binding site [chemical binding]; other site
1035817005728	activation loop (A-loop); other site
1035817005729	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1035817005730	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817005731	active site
1035817005732	ATP binding site [chemical binding]; other site
1035817005733	substrate binding site [chemical binding]; other site
1035817005734	activation loop (A-loop); other site
1035817005735	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817005736	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817005737	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817005738	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1035817005739	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1035817005740	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1035817005741	glutamine binding [chemical binding]; other site
1035817005742	catalytic triad [active]
1035817005743	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_5; cd05830
1035817005744	active site
1035817005745	catalytic site [active]
1035817005746	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1035817005747	putative septation inhibitor protein; Reviewed; Region: PRK02251
1035817005748	Rhomboid family; Region: Rhomboid; pfam01694
1035817005749	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1035817005750	homodimer interface [polypeptide binding]; other site
1035817005751	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
1035817005752	active site pocket [active]
1035817005753	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1035817005754	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1035817005755	active site
1035817005756	HIGH motif; other site
1035817005757	dimer interface [polypeptide binding]; other site
1035817005758	KMSKS motif; other site
1035817005759	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1035817005760	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1035817005761	active site
1035817005762	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1035817005763	Na binding site [ion binding]; other site
1035817005764	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1035817005765	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1035817005766	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1035817005767	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1035817005768	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
1035817005769	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1035817005770	Divergent AAA domain; Region: AAA_4; pfam04326
1035817005771	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1035817005772	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1035817005773	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005774	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005775	DNA binding site [nucleotide binding]
1035817005776	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005777	dimerization interface [polypeptide binding]; other site
1035817005778	ligand binding site [chemical binding]; other site
1035817005779	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817005780	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817005781	putative substrate translocation pore; other site
1035817005782	putative alkyl hydroperoxide reductase F subunit; Region: AhpF_homolog; TIGR03143
1035817005783	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1035817005784	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1035817005785	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1035817005786	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1035817005787	catalytic residues [active]
1035817005788	peroxiredoxin; Region: AhpC; TIGR03137
1035817005789	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1035817005790	dimer interface [polypeptide binding]; other site
1035817005791	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1035817005792	catalytic triad [active]
1035817005793	peroxidatic and resolving cysteines [active]
1035817005794	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1035817005795	active site clefts [active]
1035817005796	zinc binding site [ion binding]; other site
1035817005797	dimer interface [polypeptide binding]; other site
1035817005798	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
1035817005799	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1035817005800	Domain of unknown function DUF21; Region: DUF21; pfam01595
1035817005801	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1035817005802	Transporter associated domain; Region: CorC_HlyC; smart01091
1035817005803	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1035817005804	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1035817005805	dimerization interface [polypeptide binding]; other site
1035817005806	DPS ferroxidase diiron center [ion binding]; other site
1035817005807	ion pore; other site
1035817005808	AAA domain; Region: AAA_14; pfam13173
1035817005809	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1035817005810	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1035817005811	Protein of unknown function DUF45; Region: DUF45; pfam01863
1035817005812	hypothetical protein; Provisional; Region: PRK06062
1035817005813	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1035817005814	inhibitor-cofactor binding pocket; inhibition site
1035817005815	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817005816	catalytic residue [active]
1035817005817	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1035817005818	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1035817005819	DNA-binding site [nucleotide binding]; DNA binding site
1035817005820	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817005821	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817005822	homodimer interface [polypeptide binding]; other site
1035817005823	catalytic residue [active]
1035817005824	aspartate aminotransferase; Provisional; Region: PRK05764
1035817005825	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1035817005826	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817005827	homodimer interface [polypeptide binding]; other site
1035817005828	catalytic residue [active]
1035817005829	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1035817005830	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1035817005831	putative DNA binding site [nucleotide binding]; other site
1035817005832	putative Zn2+ binding site [ion binding]; other site
1035817005833	AsnC family; Region: AsnC_trans_reg; pfam01037
1035817005834	glutamate dehydrogenase; Provisional; Region: PRK09414
1035817005835	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1035817005836	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1035817005837	NAD(P) binding site [chemical binding]; other site
1035817005838	putative pectinesterase; Region: PLN02432; cl01911
1035817005839	Helix-turn-helix domain; Region: HTH_38; pfam13936
1035817005840	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817005841	Integrase core domain; Region: rve; pfam00665
1035817005842	Transmembrane domain of unknown function (DUF3566); Region: DUF3566; pfam12089
1035817005843	DNA gyrase subunit A; Validated; Region: PRK05560
1035817005844	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1035817005845	CAP-like domain; other site
1035817005846	active site
1035817005847	primary dimer interface [polypeptide binding]; other site
1035817005848	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005849	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005850	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005851	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005852	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005853	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1035817005854	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1035817005855	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817005856	Mg2+ binding site [ion binding]; other site
1035817005857	G-X-G motif; other site
1035817005858	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1035817005859	anchoring element; other site
1035817005860	dimer interface [polypeptide binding]; other site
1035817005861	ATP binding site [chemical binding]; other site
1035817005862	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1035817005863	active site
1035817005864	putative metal-binding site [ion binding]; other site
1035817005865	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1035817005866	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1035817005867	recombination protein F; Reviewed; Region: recF; PRK00064
1035817005868	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817005869	Walker A/P-loop; other site
1035817005870	ATP binding site [chemical binding]; other site
1035817005871	Q-loop/lid; other site
1035817005872	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1035817005873	ABC transporter signature motif; other site
1035817005874	Walker B; other site
1035817005875	D-loop; other site
1035817005876	H-loop/switch region; other site
1035817005877	DNA polymerase III subunit beta; Validated; Region: PRK07761
1035817005878	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1035817005879	putative DNA binding surface [nucleotide binding]; other site
1035817005880	dimer interface [polypeptide binding]; other site
1035817005881	beta-clamp/clamp loader binding surface; other site
1035817005882	beta-clamp/translesion DNA polymerase binding surface; other site
1035817005883	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1035817005884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1035817005885	Walker A motif; other site
1035817005886	ATP binding site [chemical binding]; other site
1035817005887	Walker B motif; other site
1035817005888	arginine finger; other site
1035817005889	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1035817005890	DnaA box-binding interface [nucleotide binding]; other site
1035817005891	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1035817005892	Ribonuclease P; Region: Ribonuclease_P; pfam00825
1035817005893	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1035817005894	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1035817005895	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1035817005896	G-X-X-G motif; other site
1035817005897	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1035817005898	RxxxH motif; other site
1035817005899	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1035817005900	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1035817005901	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1035817005902	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817005903	P-loop; other site
1035817005904	Magnesium ion binding site [ion binding]; other site
1035817005905	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1035817005906	Magnesium ion binding site [ion binding]; other site
1035817005907	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1035817005908	ParB-like nuclease domain; Region: ParBc; pfam02195
1035817005909	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817005910	MULE transposase domain; Region: MULE; pfam10551
1035817005911	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817005912	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005913	dimer interface [polypeptide binding]; other site
1035817005914	conserved gate region; other site
1035817005915	putative PBP binding loops; other site
1035817005916	ABC-ATPase subunit interface; other site
1035817005917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817005918	dimer interface [polypeptide binding]; other site
1035817005919	conserved gate region; other site
1035817005920	putative PBP binding loops; other site
1035817005921	ABC-ATPase subunit interface; other site
1035817005922	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817005923	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817005924	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817005925	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817005926	DNA binding site [nucleotide binding]
1035817005927	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817005928	ligand binding site [chemical binding]; other site
1035817005929	dimerization interface [polypeptide binding]; other site
1035817005930	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1035817005931	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1035817005932	Ca binding site [ion binding]; other site
1035817005933	active site
1035817005934	catalytic site [active]
1035817005935	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1035817005936	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1035817005937	active site
1035817005938	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1035817005939	MULE transposase domain; Region: MULE; pfam10551
1035817005940	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1035817005941	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1035817005942	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1035817005943	integral membrane protein MviN; Region: mviN; TIGR01695
1035817005944	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1035817005945	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
1035817005946	active site
1035817005947	Ap6A binding site [chemical binding]; other site
1035817005948	nudix motif; other site
1035817005949	metal binding site [ion binding]; metal-binding site
1035817005950	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
1035817005951	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1035817005952	active site
1035817005953	NTP binding site [chemical binding]; other site
1035817005954	metal binding triad [ion binding]; metal-binding site
1035817005955	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1035817005956	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1035817005957	Zn2+ binding site [ion binding]; other site
1035817005958	Mg2+ binding site [ion binding]; other site
1035817005959	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1035817005960	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
1035817005961	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK03188
1035817005962	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1035817005963	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1035817005964	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1035817005965	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3583
1035817005966	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1035817005967	G5 domain; Region: G5; pfam07501
1035817005968	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1035817005969	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1035817005970	catalytic residue [active]
1035817005971	Gamma interferon inducible lysosomal thiol reductase (GILT); Region: GILT; pfam03227
1035817005972	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1035817005973	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1035817005974	active site
1035817005975	ATP binding site [chemical binding]; other site
1035817005976	substrate binding site [chemical binding]; other site
1035817005977	activation loop (A-loop); other site
1035817005978	similar to truncated glycoside hydrolase; BLNIAS_02875
1035817005979	AAA ATPase domain; Region: AAA_16; pfam13191
1035817005980	Ion channel; Region: Ion_trans_2; pfam07885
1035817005981	Protein of unknown function (DUF3990); Region: DUF3990; pfam13151
1035817005982	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1035817005983	non-specific DNA binding site [nucleotide binding]; other site
1035817005984	salt bridge; other site
1035817005985	sequence-specific DNA binding site [nucleotide binding]; other site
1035817005986	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1035817005987	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1035817005988	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1035817005989	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1035817005990	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1035817005991	catalytic residues [active]
1035817005992	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1035817005993	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1035817005994	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1035817005995	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1035817005996	active site
1035817005997	dimer interface [polypeptide binding]; other site
1035817005998	catalytic residues [active]
1035817005999	effector binding site; other site
1035817006000	R2 peptide binding site; other site
1035817006001	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1035817006002	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1035817006003	dimer interface [polypeptide binding]; other site
1035817006004	putative radical transfer pathway; other site
1035817006005	diiron center [ion binding]; other site
1035817006006	tyrosyl radical; other site
1035817006007	Domain of unknown function (DUF4401); Region: DUF4401; pfam14351
1035817006008	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1035817006009	ATP binding site [chemical binding]; other site
1035817006010	Mg2+ binding site [ion binding]; other site
1035817006011	G-X-G motif; other site
1035817006012	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1035817006013	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1035817006014	active site
1035817006015	phosphorylation site [posttranslational modification]
1035817006016	intermolecular recognition site; other site
1035817006017	dimerization interface [polypeptide binding]; other site
1035817006018	LytTr DNA-binding domain; Region: LytTR; smart00850
1035817006019	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1035817006020	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1035817006021	active site
1035817006022	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1035817006023	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1035817006024	Walker A/P-loop; other site
1035817006025	ATP binding site [chemical binding]; other site
1035817006026	Q-loop/lid; other site
1035817006027	ABC transporter signature motif; other site
1035817006028	Walker B; other site
1035817006029	D-loop; other site
1035817006030	H-loop/switch region; other site
1035817006031	TOBE domain; Region: TOBE_2; pfam08402
1035817006032	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
1035817006033	Cna protein B-type domain; Region: Cna_B; pfam05738
1035817006034	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
1035817006035	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
1035817006036	active site
1035817006037	catalytic site [active]
1035817006038	Domain of unknown function (DUF4032); Region: DUF4032; pfam13224
1035817006039	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1035817006040	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1035817006041	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1035817006042	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817006043	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1035817006044	putative substrate translocation pore; other site
1035817006045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1035817006046	putative substrate translocation pore; other site
1035817006047	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1035817006048	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1035817006049	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1035817006050	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1035817006051	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1035817006052	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1035817006053	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1035817006054	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1035817006055	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1035817006056	trimer interface [polypeptide binding]; other site
1035817006057	active site
1035817006058	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1035817006059	Serine hydrolase (FSH1); Region: FSH1; pfam03959
1035817006060	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1035817006061	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1035817006062	nucleoside/Zn binding site; other site
1035817006063	dimer interface [polypeptide binding]; other site
1035817006064	catalytic motif [active]
1035817006065	Melibiase; Region: Melibiase; pfam02065
1035817006066	MarR family; Region: MarR_2; pfam12802
1035817006067	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1035817006068	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1035817006069	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1035817006070	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817006071	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1035817006072	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1035817006073	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817006074	dimer interface [polypeptide binding]; other site
1035817006075	conserved gate region; other site
1035817006076	putative PBP binding loops; other site
1035817006077	ABC-ATPase subunit interface; other site
1035817006078	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817006079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817006080	dimer interface [polypeptide binding]; other site
1035817006081	conserved gate region; other site
1035817006082	putative PBP binding loops; other site
1035817006083	ABC-ATPase subunit interface; other site
1035817006084	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817006085	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cl17402
1035817006086	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817006087	ligand binding site [chemical binding]; other site
1035817006088	dimerization interface [polypeptide binding]; other site
1035817006089	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1035817006090	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1035817006091	DNA binding site [nucleotide binding]
1035817006092	domain linker motif; other site
1035817006093	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1035817006094	ligand binding site [chemical binding]; other site
1035817006095	dimerization interface [polypeptide binding]; other site
1035817006096	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817006097	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817006098	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
1035817006099	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1035817006100	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1035817006101	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1035817006102	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817006103	dimer interface [polypeptide binding]; other site
1035817006104	conserved gate region; other site
1035817006105	putative PBP binding loops; other site
1035817006106	ABC-ATPase subunit interface; other site
1035817006107	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1035817006108	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1035817006109	dimer interface [polypeptide binding]; other site
1035817006110	conserved gate region; other site
1035817006111	putative PBP binding loops; other site
1035817006112	ABC-ATPase subunit interface; other site
1035817006113	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins; Region: AmyAc_OligoGlu_TS; cd11332
1035817006114	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1035817006115	active site
1035817006116	catalytic site [active]
1035817006117	probable galactinol--sucrose galactosyltransferase 1; Region: PLN02355
1035817006118	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1035817006119	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1035817006120	Ca binding site [ion binding]; other site
1035817006121	active site
1035817006122	catalytic site [active]
1035817006123	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1035817006124	tetramer interface [polypeptide binding]; other site
1035817006125	threonine dehydratase; Provisional; Region: PRK08198
1035817006126	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1035817006127	catalytic residue [active]
1035817006128	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
1035817006129	NAD-dependent deacetylase; Provisional; Region: PRK00481
1035817006130	SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent...; Region: SIRT7; cd01410
1035817006131	NAD+ binding site [chemical binding]; other site
1035817006132	substrate binding site [chemical binding]; other site
1035817006133	Zn binding site [ion binding]; other site
1035817006134	Helix-turn-helix domain; Region: HTH_38; pfam13936
1035817006135	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1035817006136	Integrase core domain; Region: rve; pfam00665
1035817006137	MobA/MobL family; Region: MobA_MobL; pfam03389
1035817006138	potential frameshift: common BLAST hit: gi|213692061|ref|YP_002322647.1| transposase, IS605 OrfB family
1035817006139	Probable transposase; Region: OrfB_IS605; pfam01385
1035817006140	Initiator Replication protein; Region: Rep_3; pfam01051