-- dump date   	20140619_004839
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002222491.1	2 amidation motifs (Prosite)
YP_002222493.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002222496.1	LEUCINE_ZIPPER motif (Prosite)
YP_002222497.1	amidation motif (Prosite)
YP_002222500.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002222503.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_002222505.1	amidation motif (Prosite)
YP_002222508.1	catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate
YP_002222510.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002222511.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002222514.1	MICROBODIES_CTER motif (Prosite)
YP_002222520.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002222522.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002222523.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002222525.1	Probable lipoprotein (SpLip)
YP_002222531.1	ATP_GTP_A and LEUCINE_ZIPPER motif (Prosite)
YP_002222532.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002222537.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002222539.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002222540.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002222544.1	UPF0054 motif (Prosite)
YP_002222546.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002222549.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002222551.1	MICROBODIES_CTER and DDC_GAD_HDC_YDC motifs (Prosite)
YP_002222552.1	COF_1 and COF_2 motifs (Prosite)
YP_002222555.1	Probable lipoprotein (SpLip)
YP_002222558.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_002222569.1	ATP_GTP_A motif (Prosite)
YP_002222571.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002222572.1	RGD motif (Prosite)
YP_002222573.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits
YP_002222574.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.
YP_002222575.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex
YP_002222576.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex
YP_002222577.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex
YP_002222579.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the E subunit is part of the catalytic core of the ATP synthase complex
YP_002222581.1	ATP_GTP_A motif (Prosite)
YP_002222583.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002222585.1	predicted phosphoribosyltransferases
YP_002222589.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002222590.1	RGD motif (Prosite)
YP_002222592.1	RGD motif (Prosite)
YP_002222594.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002222595.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002222597.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002222598.1	ZINC_PROTEASE and amidation motifs (Prosite)
YP_002222600.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_002222601.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_002222602.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002222603.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002222608.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002222612.1	contains N-terminal domain of unknown function fused to transcription elongation factor; GreA is necessary for efficient RNA polymerization through arresting sites; cleaves the nascent transcript and allows resumption of transcription elongation
YP_002222615.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002222621.1	LEUCINE_ZIPPER motif (Prosite)
YP_002222623.1	Probable lipoprotein (SpLip)
YP_002222626.1	structural flagella protein
YP_002222627.1	involved in flagellin assembly
YP_002222629.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
YP_002222631.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002222643.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002222644.1	2 amidation motifs and one RGD (Prosite)
YP_002222645.1	RGD motif (Prosite); Probable lipoprotein (SpLip)
YP_002222652.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_002222653.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_002222655.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002222656.1	With FlgK acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002222657.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_002222660.1	ATP_GTP_A motif (Prosite)
YP_002222662.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002222664.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_002222666.1	Possible lipoprotein (SpLip)
YP_002222669.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002222670.1	AMIDATION and N6_MTASE motifs (Prosite)
YP_002222673.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002222676.1	amidation motif (Prosite)
YP_002222678.1	amidation motif (Prosite)
YP_002222686.1	Probable lipoprotein (SpLip)
YP_002222691.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_002222692.1	amidation motif (Prosite)
YP_002222693.1	catalyzes a two-step reaction, first charging an alanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002222698.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002222699.1	Probable lipoprotein (SpLip)
YP_002222700.1	amidation motif (Prosite)
YP_002222701.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002222702.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002222704.1	HISTONE_LIKE motif (Prosite)
YP_002222705.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002222707.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002222708.1	amidation motif (Prosite)
YP_002222709.1	Transfers the fatty acyl group on membrane lipoproteins
YP_002222714.1	Probable lipoprotein (SpLip)
YP_002222718.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_002222722.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002222723.1	MICROBODIES_CTER motif (Prosite)
YP_002222728.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002222730.1	Amidation motif (Prosite)
YP_002222731.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002222733.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002222734.1	Probable lipoprotein (SpLip)
YP_002222735.1	LEUCINE_ZIPPER motif (Prosite)
YP_002222737.1	putative membrane proteins related to metalloendopeptidases
YP_002222742.1	amidation motif (Prosite)
YP_002222743.1	amidation motif (Prosite)
YP_002222745.1	Positive regulator of class III flagellar genes
YP_002222746.1	membrane protein involved in the flagellar export apparatus
YP_002222747.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_002222750.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_002222751.1	possible structural component of the flagellum that anchors the rod to the membrane
YP_002222753.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_002222754.1	interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring
YP_002222755.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002222758.1	the hook connects flagellar basal body to the flagellar filament
YP_002222759.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod
YP_002222764.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_002222765.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002222766.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_002222767.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_002222768.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_002222769.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod
YP_002222770.1	heat shock protein involved in degradation of misfolded proteins
YP_002222771.1	heat shock protein involved in degradation of misfolded proteins
YP_002222772.1	Probable lipoprotein (SpLip)
YP_002222773.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002222777.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002222783.1	MULTICOPPER_OXIDASE1 motif (Prosite)
YP_002222791.1	amidation motif (Prosite)
YP_002222793.1	LEUCINE_ZIPPER motif (Prosite)
YP_002222795.1	Probable lipoprotein (SpLip)
YP_002222796.1	Probable lipoprotein (SpLip)
YP_002222801.1	Possible lipoprotein (SpLip)
YP_002222806.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002222807.1	forms a direct contact with the tRNA during translation
YP_002222808.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002222810.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002222811.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002222812.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_002222814.1	AMIDATION
YP_002222817.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002222818.1	required for 70S ribosome assembly
YP_002222820.1	Probable lipoprotein (SpLip)
YP_002222825.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002222829.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002222831.1	catalyzes the removal of amino acids from the N termini of peptides
YP_002222833.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002222835.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002222836.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002222840.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002222841.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_002222846.1	Probable lipoprotein (SpLip)
YP_002222847.1	Probable lipoprotein (SpLip)
YP_002222849.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002222850.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002222851.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002222852.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002222853.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_002222854.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002222855.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002222856.1	binds directly to 23S ribosomal RNA
YP_002222858.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002222859.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002222861.1	Probable lipoprotein (SpLip)
YP_002222862.1	Probable lipoprotein (SpLip)
YP_002222865.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002222874.1	Probable lipoprotein (SpLip)
YP_002222878.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002222885.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002222887.1	RGD and UPF0011 motifs (Prosite)
YP_002222898.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002222900.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_002222903.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_002222905.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002222911.1	AMIDATION and MICROBODIES_CTER motifs (Prosite)
YP_002222913.1	AMIDATION motif (Prosite)
YP_002222915.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002222918.1	Probable lipoprotein (SpLip)
YP_002222919.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002222922.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002222927.1	amidation and RGD motifs (Prosite)
YP_002222929.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002222931.1	amidation motif (Prosite)
YP_002222932.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002222934.1	Probable lipoprotein (SpLip)
YP_002222935.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002222936.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002222937.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002222938.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002222939.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002222940.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002222941.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002222942.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002222943.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002222944.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002222945.1	one of the stabilizing components for the large ribosomal subunit
YP_002222946.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002222947.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002222948.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002222949.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002222950.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_002222951.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002222952.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002222953.1	binds 5S rRNA along with protein L5 and L25
YP_002222954.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002222955.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002222956.1	late assembly protein
YP_002222957.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002222958.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_002222959.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002222960.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002222961.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002222962.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002222963.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_002222966.1	LEUCINE_ZIPPER and MICROBODIES_CTER motifs (Prosite)
YP_002222967.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002222970.1	RGD and LEUCINE_ZIPPER motifs (Prosite)
YP_002222971.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002222972.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002222975.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002222976.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002222981.1	2 LEUCINE_ZIPPER motifs (Prosite)
YP_002222982.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_002222983.1	LEUCINE_ZIPPER motif (Prosite)
YP_002222988.1	amidation motif (Prosite)
YP_002222989.1	Probable lipoprotein (SpLip)
YP_002222990.1	ZINC_PROTEASE motif (Prosite)
YP_002222994.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002222996.1	LEUCINE_ZIPPER and AMIDATION motifs (Prosite)
YP_002222997.1	Probable lipoprotein (SpLip)
YP_002222999.1	Catalyzes the formation of PRPP from ATP and ribose 5-phosphate
YP_002223002.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_002223007.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_002223009.1	amidation motif (Prosite)
YP_002223014.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
YP_002223015.1	molecular chaperone
YP_002223016.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002223026.1	putative peptidase , M20/M25/M40 family
YP_002223027.1	Catalyzes the phosphorylation of UMP to UDP
YP_002223030.1	LEUCINE_ZIPPER motif (Prosite)
YP_002223031.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002223034.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_002223036.1	catalyzes branch migration in Holliday junction intermediates
YP_002223041.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002223043.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002223047.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002223051.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002223052.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002223054.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002223059.1	catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors
YP_002223061.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002223062.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002223063.1	binds and unfolds substrates as part of the ClpXP protease
YP_002223065.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002223066.1	2 amidation motifs (Prosite)
YP_002223072.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002223076.1	catalyzes the removal of amino acids from the N termini of peptides
YP_002223083.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_002223084.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002223086.1	Probable lipoprotein (SpLip)
YP_002223090.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
YP_002223091.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_002223095.1	AMIDATION motif (Prosite)
YP_002223096.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002223099.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_002223100.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002223105.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002223106.1	class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine
YP_002223107.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002223110.1	Possible lipoprotein (SpLip)
YP_002223111.1	Probable lipoprotein (SpLip)
YP_002223129.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002223131.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
YP_002223136.1	Possible lipoprotein (SpLip)
YP_002223138.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002223141.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002223142.1	putative RNA-binding protein; amidation motif (Prosite)
YP_002223143.1	Essential for efficient processing of 16S rRNA
YP_002223144.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002223145.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002223147.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002223148.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002223149.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002223150.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002223152.1	LEUCINE_ZIPPER motif (Prosite)
YP_002223153.1	amidation motif (Prosite)
YP_002223154.1	amidation motif (Prosite)
YP_002223156.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_002223159.1	functions in MreBCD complex in some organisms
YP_002223160.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_002223164.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_002223165.1	Possible lipoprotein (SpLip)
YP_002223171.1	catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate
YP_002223172.1	CoADR; specific for coenzyme A disulfide; requires NADH; involved in protecting cells against reactive oxygen species by recycling coenzyme A disulfide which can reduce hydrogen peroxide
YP_002223174.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002223179.1	amidation motif (Prosite)
YP_002223183.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002223184.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002223186.1	amidation motif (Prosite)
YP_002223194.1	amidation motif (Prosite)
YP_002223197.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_002223198.1	AMIDATION motif (Prosite)
YP_002223199.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002223200.1	LEUCINE_ZIPPER motif (Prosite); Possible lipoprotein (SpLip)
YP_002223203.1	RGD motif (Prosite)
YP_002223208.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002223210.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002223214.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_002223216.1	makes up the distal portion of the flagellar basal body rod
YP_002223219.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002223222.1	involved in the peptidyltransferase reaction during translation
YP_002223223.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002223227.1	stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
YP_002223228.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_002223229.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002223233.1	Possible lipoprotein (SpLip)
YP_002223237.1	SERPIN motif (Prosite)
YP_002223241.1	This protein performs the mismatch recognition step during the DNA repair process
YP_002223242.1	amidation motif (Prosite)
YP_002223243.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002223244.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002223247.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_002223249.1	Probable lipoprotein (SpLip)
YP_002223250.1	AKH motif (Prosite)
YP_002223252.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_002223256.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
YP_002223259.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002223261.1	catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_002223263.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002223264.1	Possible lipoprotein (SpLip)
YP_002223274.1	Probable lipoprotein (SpLip)
YP_002223275.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)
YP_002223278.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002223279.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002223282.1	Probable lipoprotein (SpLip)
YP_002223283.1	catalyzes the degradation of arginine to citruline and ammonia
YP_002223284.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_002223325.1	Probable lipoprotein (SpLip)
YP_002223328.1	Possible lipoprotein (SpLip)
YP_002223330.1	RGD motif (Prosite); Possible lipoprotein (SpLip)
YP_002223331.1	RGD motif (Prosite)
YP_002223333.1	Probable lipoprotein (SpLip)
YP_002223338.1	Probable lipoprotein (SpLip)
YP_002223339.1	Possible lipoprotein (SpLip)
YP_002223340.1	Probable lipoprotein (SpLip)
YP_002223341.1	Probable lipoprotein (SpLip)
YP_002223342.1	Probable lipoprotein (SpLip)
YP_002223343.1	Probable lipoprotein (SpLip)
YP_002223344.1	Probable lipoprotein (SpLip)
YP_002223345.1	SBP_BACTERIAL_3 motif (Prosite)
YP_002223346.1	Probable lipoprotein (SpLip)
YP_002223347.1	PRENYLATION motif (Prosite); Probable lipoprotein (SpLip)
YP_002223350.1	RGD motif (Prosite)
YP_002223351.1	Probable lipoprotein (SpLip)
YP_002223355.1	Probable lipoprotein (SpLip)
YP_002223356.1	Probable lipoprotein (SpLip)
YP_002223357.1	Probable lipoprotein (SpLip)
YP_002223358.1	Probable lipoprotein (SpLip)
YP_002223363.1	Probable lipoprotein (SpLip)
YP_002223364.1	Possible lipoprotein (SpLip)
YP_002223378.1	Probable lipoprotein (SpLip)
YP_002223380.1	Probable lipoprotein (SpLip)
YP_002223382.1	Possible lipoprotein (SpLip)
YP_002223383.1	Possible lipoprotein (SpLip)
YP_002223384.1	ATP_GTP_A motif (Prosite)
YP_002223388.1	Possible lipoprotein (SpLip)
YP_002223397.1	Probable lipoprotein (SpLip)
YP_002223402.1	Probable lipoprotein (SpLip)
YP_002223404.1	Probable lipoprotein (SpLip)
YP_002223411.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002223413.1	Probable lipoprotein (SpLip)
YP_002223635.1	Probable lipoprotein (SpLip)
YP_002223636.1	Probable lipoprotein (SpLip)
YP_002223639.1	catalyzes the hydrolysis of acylphosphate
YP_002223641.1	amidation motif (Prosite)
YP_002223642.1	Probable lipoprotein (SpLip)
YP_002223647.1	Probable lipoprotein (SpLip)
YP_002223648.1	Probable lipoprotein (SpLip)
YP_002223657.1	Probable lipoprotein (SpLip)
YP_002223658.1	Probable lipoprotein (SpLip)
YP_002223660.1	Probable lipoprotein (SpLip)
YP_002223661.1	Probable lipoprotein (SpLip)
YP_002223691.1	Probable lipoprotein (SpLip)
YP_002223769.1	Probable lipoprotein (SpLip)
YP_002223770.1	flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor
YP_002223772.1	Probable lipoprotein (SpLip)
YP_002223773.1	Probable lipoprotein (SpLip)
YP_002223774.1	Probable lipoprotein (SpLip)
YP_002223782.1	Probable lipoprotein (SpLip)
YP_002223800.1	Probable lipoprotein (SpLip)
YP_002223813.1	Probable lipoprotein (SpLip)
YP_002223822.1	Probable lipoprotein (SpLip)