-- dump date   	20140619_005144
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
526224000001	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
526224000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
526224000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224000004	Walker A motif; other site
526224000005	ATP binding site [chemical binding]; other site
526224000006	Walker B motif; other site
526224000007	arginine finger; other site
526224000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
526224000009	DnaA box-binding interface [nucleotide binding]; other site
526224000010	GrpE; Region: GrpE; pfam01025
526224000011	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
526224000012	dimer interface [polypeptide binding]; other site
526224000013	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
526224000014	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
526224000015	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
526224000016	nucleotide binding site [chemical binding]; other site
526224000017	NEF interaction site [polypeptide binding]; other site
526224000018	SBD interface [polypeptide binding]; other site
526224000019	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000020	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000021	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224000022	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224000023	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
526224000024	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
526224000025	HSP70 interaction site [polypeptide binding]; other site
526224000026	chaperone protein DnaJ; Provisional; Region: PRK10767
526224000027	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
526224000028	HSP70 interaction site [polypeptide binding]; other site
526224000029	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
526224000030	substrate binding site [polypeptide binding]; other site
526224000031	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
526224000032	Zn binding sites [ion binding]; other site
526224000033	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
526224000034	dimer interface [polypeptide binding]; other site
526224000035	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
526224000036	Formaldehyde dehydrogenases; Region: FDH_like; cd05278
526224000037	catalytic Zn binding site [ion binding]; other site
526224000038	NAD(P) binding site [chemical binding]; other site
526224000039	structural Zn binding site [ion binding]; other site
526224000040	excinuclease ABC subunit B; Provisional; Region: PRK05298
526224000041	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224000042	ATP binding site [chemical binding]; other site
526224000043	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224000044	nucleotide binding region [chemical binding]; other site
526224000045	ATP-binding site [chemical binding]; other site
526224000046	Ultra-violet resistance protein B; Region: UvrB; pfam12344
526224000047	UvrB/uvrC motif; Region: UVR; pfam02151
526224000048	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
526224000049	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224000050	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
526224000051	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224000052	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000053	binding surface
526224000054	TPR motif; other site
526224000055	TPR repeat; Region: TPR_11; pfam13414
526224000056	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000057	TPR motif; other site
526224000058	binding surface
526224000059	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
526224000060	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
526224000061	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
526224000062	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
526224000063	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224000064	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
526224000065	putative substrate binding site [chemical binding]; other site
526224000066	putative ATP binding site [chemical binding]; other site
526224000067	TPR repeat; Region: TPR_11; pfam13414
526224000068	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000069	binding surface
526224000070	TPR motif; other site
526224000071	Bifunctional nuclease; Region: DNase-RNase; pfam02577
526224000072	UvrB/uvrC motif; Region: UVR; pfam02151
526224000073	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
526224000074	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
526224000075	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
526224000076	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
526224000077	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
526224000078	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224000079	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224000080	Walker A motif; other site
526224000081	ATP binding site [chemical binding]; other site
526224000082	Walker B motif; other site
526224000083	arginine finger; other site
526224000084	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
526224000085	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
526224000086	putative active site [active]
526224000087	putative metal binding site [ion binding]; other site
526224000088	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
526224000089	Domain of unknown function DUF21; Region: DUF21; pfam01595
526224000090	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
526224000091	Transporter associated domain; Region: CorC_HlyC; smart01091
526224000092	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
526224000093	amidase catalytic site [active]
526224000094	Zn binding residues [ion binding]; other site
526224000095	substrate binding site [chemical binding]; other site
526224000096	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
526224000097	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
526224000098	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
526224000099	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
526224000100	active site
526224000101	PHP Thumb interface [polypeptide binding]; other site
526224000102	metal binding site [ion binding]; metal-binding site
526224000103	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
526224000104	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
526224000105	active site
526224000106	HIGH motif; other site
526224000107	dimer interface [polypeptide binding]; other site
526224000108	KMSKS motif; other site
526224000109	PSP1 C-terminal conserved region; Region: PSP1; cl00770
526224000110	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224000111	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224000112	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224000113	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224000114	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
526224000115	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
526224000116	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
526224000117	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
526224000118	active site residue [active]
526224000119	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
526224000120	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
526224000121	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
526224000122	GIY-YIG motif/motif A; other site
526224000123	active site
526224000124	catalytic site [active]
526224000125	putative DNA binding site [nucleotide binding]; other site
526224000126	metal binding site [ion binding]; metal-binding site
526224000127	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
526224000128	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
526224000129	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
526224000130	Helix-turn-helix domain; Region: HTH_36; pfam13730
526224000131	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
526224000132	Phenazine biosynthesis-like protein; Region: PhzC-PhzF; pfam02567
526224000133	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
526224000134	substrate binding site [chemical binding]; other site
526224000135	multimerization interface [polypeptide binding]; other site
526224000136	ATP binding site [chemical binding]; other site
526224000137	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
526224000138	Sodium Bile acid symporter family; Region: SBF; pfam01758
526224000139	Glycerol dehydrogenase-like; Region: GlyDH-like2; cd08171
526224000140	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
526224000141	putative active site [active]
526224000142	metal binding site [ion binding]; metal-binding site
526224000143	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
526224000144	Cache domain; Region: Cache_1; pfam02743
526224000145	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224000146	dimer interface [polypeptide binding]; other site
526224000147	putative CheW interface [polypeptide binding]; other site
526224000148	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
526224000149	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
526224000150	acyl-activating enzyme (AAE) consensus motif; other site
526224000151	AMP binding site [chemical binding]; other site
526224000152	active site
526224000153	CoA binding site [chemical binding]; other site
526224000154	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
526224000155	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
526224000156	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
526224000157	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
526224000158	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000159	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
526224000160	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
526224000161	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224000162	motif II; other site
526224000163	MoxR-like ATPases [General function prediction only]; Region: COG0714
526224000164	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224000165	Walker A motif; other site
526224000166	ATP binding site [chemical binding]; other site
526224000167	Walker B motif; other site
526224000168	arginine finger; other site
526224000169	hypothetical protein; Provisional; Region: yieM; PRK10997
526224000170	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
526224000171	metal ion-dependent adhesion site (MIDAS); other site
526224000172	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
526224000173	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
526224000174	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
526224000175	active site
526224000176	catalytic residues [active]
526224000177	metal binding site [ion binding]; metal-binding site
526224000178	homodimer binding site [polypeptide binding]; other site
526224000179	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
526224000180	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
526224000181	carboxyltransferase (CT) interaction site; other site
526224000182	biotinylation site [posttranslational modification]; other site
526224000183	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
526224000184	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
526224000185	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
526224000186	Ligand binding site; other site
526224000187	Putative Catalytic site; other site
526224000188	DXD motif; other site
526224000189	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
526224000190	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
526224000191	Predicted transcriptional regulators [Transcription]; Region: COG1733
526224000192	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
526224000193	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
526224000194	hydrophobic ligand binding site; other site
526224000195	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
526224000196	Domain of unknown function DUF20; Region: UPF0118; pfam01594
526224000197	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000198	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224000199	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224000200	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224000201	Outer membrane efflux protein; Region: OEP; pfam02321
526224000202	Outer membrane efflux protein; Region: OEP; pfam02321
526224000203	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
526224000204	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
526224000205	DNA-binding site [nucleotide binding]; DNA binding site
526224000206	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
526224000207	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000208	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
526224000209	active site turn [active]
526224000210	phosphorylation site [posttranslational modification]
526224000211	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
526224000212	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
526224000213	HPr interaction site; other site
526224000214	glycerol kinase (GK) interaction site [polypeptide binding]; other site
526224000215	active site
526224000216	phosphorylation site [posttranslational modification]
526224000217	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
526224000218	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
526224000219	Ca binding site [ion binding]; other site
526224000220	active site
526224000221	catalytic site [active]
526224000222	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
526224000223	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
526224000224	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
526224000225	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
526224000226	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
526224000227	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
526224000228	Predicted transcriptional regulator [Transcription]; Region: COG2378
526224000229	WYL domain; Region: WYL; pfam13280
526224000230	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
526224000231	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
526224000232	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
526224000233	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
526224000234	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224000235	active site
526224000236	phosphorylation site [posttranslational modification]
526224000237	intermolecular recognition site; other site
526224000238	dimerization interface [polypeptide binding]; other site
526224000239	CheB methylesterase; Region: CheB_methylest; pfam01339
526224000240	CheD chemotactic sensory transduction; Region: CheD; cl00810
526224000241	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
526224000242	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
526224000243	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224000244	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
526224000245	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
526224000246	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
526224000247	putative binding surface; other site
526224000248	active site
526224000249	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
526224000250	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224000251	ATP binding site [chemical binding]; other site
526224000252	Mg2+ binding site [ion binding]; other site
526224000253	G-X-G motif; other site
526224000254	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
526224000255	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
526224000256	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224000257	active site
526224000258	phosphorylation site [posttranslational modification]
526224000259	intermolecular recognition site; other site
526224000260	dimerization interface [polypeptide binding]; other site
526224000261	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
526224000262	NAD synthetase; Provisional; Region: PRK13981
526224000263	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
526224000264	multimer interface [polypeptide binding]; other site
526224000265	active site
526224000266	catalytic triad [active]
526224000267	protein interface 1 [polypeptide binding]; other site
526224000268	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
526224000269	Ligand Binding Site [chemical binding]; other site
526224000270	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; cl17869
526224000271	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224000272	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224000273	ligand binding site [chemical binding]; other site
526224000274	flexible hinge region; other site
526224000275	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
526224000276	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000277	binding surface
526224000278	TPR motif; other site
526224000279	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224000280	CRP/FNR family transcriptional regulator; Provisional; Region: PRK13918
526224000281	ligand binding site [chemical binding]; other site
526224000282	flexible hinge region; other site
526224000283	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
526224000284	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000285	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000286	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000287	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000288	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
526224000289	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
526224000290	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
526224000291	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
526224000292	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
526224000293	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
526224000294	prolyl-tRNA synthetase; Provisional; Region: PRK09194
526224000295	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
526224000296	dimer interface [polypeptide binding]; other site
526224000297	motif 1; other site
526224000298	active site
526224000299	motif 2; other site
526224000300	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
526224000301	putative deacylase active site [active]
526224000302	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
526224000303	active site
526224000304	motif 3; other site
526224000305	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
526224000306	anticodon binding site; other site
526224000307	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
526224000308	Predicted permeases [General function prediction only]; Region: COG0795
526224000309	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
526224000310	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
526224000311	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
526224000312	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000313	active site
526224000314	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
526224000315	putative trimer interface [polypeptide binding]; other site
526224000316	putative CoA binding site [chemical binding]; other site
526224000317	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224000318	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224000319	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
526224000320	FAD binding site [chemical binding]; other site
526224000321	LPP20 lipoprotein; Region: LPP20; pfam02169
526224000322	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
526224000323	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
526224000324	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
526224000325	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
526224000326	Methyltransferase domain; Region: Methyltransf_23; pfam13489
526224000327	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224000328	S-adenosylmethionine binding site [chemical binding]; other site
526224000329	Radical SAM superfamily; Region: Radical_SAM; pfam04055
526224000330	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224000331	FeS/SAM binding site; other site
526224000332	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224000333	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224000334	active site
526224000335	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224000336	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224000337	active site
526224000338	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224000339	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224000340	active site
526224000341	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
526224000342	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224000343	NAD(P) binding site [chemical binding]; other site
526224000344	active site
526224000345	Methyltransferase domain; Region: Methyltransf_23; pfam13489
526224000346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224000347	S-adenosylmethionine binding site [chemical binding]; other site
526224000348	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
526224000349	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
526224000350	PYR/PP interface [polypeptide binding]; other site
526224000351	dimer interface [polypeptide binding]; other site
526224000352	TPP binding site [chemical binding]; other site
526224000353	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
526224000354	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
526224000355	TPP-binding site [chemical binding]; other site
526224000356	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
526224000357	active site
526224000358	catalytic residues [active]
526224000359	metal binding site [ion binding]; metal-binding site
526224000360	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
526224000361	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
526224000362	inhibitor-cofactor binding pocket; inhibition site
526224000363	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224000364	catalytic residue [active]
526224000365	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
526224000366	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224000367	NAD(P) binding site [chemical binding]; other site
526224000368	active site
526224000369	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
526224000370	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
526224000371	substrate binding site; other site
526224000372	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224000373	active site
526224000374	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
526224000375	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000376	active site
526224000377	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000378	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
526224000379	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
526224000380	active site
526224000381	homodimer interface [polypeptide binding]; other site
526224000382	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224000383	FeS/SAM binding site; other site
526224000384	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224000385	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000386	active site
526224000387	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
526224000388	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
526224000389	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224000390	NAD(P) binding site [chemical binding]; other site
526224000391	active site
526224000392	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
526224000393	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
526224000394	NAD(P) binding site [chemical binding]; other site
526224000395	homodimer interface [polypeptide binding]; other site
526224000396	substrate binding site [chemical binding]; other site
526224000397	active site
526224000398	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
526224000399	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
526224000400	4Fe-4S binding domain; Region: Fer4; pfam00037
526224000401	coenzyme F420-reducing hydrogenase subunit beta; Validated; Region: PRK09325
526224000402	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Region: FrhB_FdhB_N; pfam04422
526224000403	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
526224000404	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
526224000405	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
526224000406	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
526224000407	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224000408	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
526224000409	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
526224000410	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
526224000411	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
526224000412	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
526224000413	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
526224000414	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
526224000415	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
526224000416	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224000417	Walker A/P-loop; other site
526224000418	ATP binding site [chemical binding]; other site
526224000419	Q-loop/lid; other site
526224000420	ABC transporter signature motif; other site
526224000421	Walker B; other site
526224000422	D-loop; other site
526224000423	H-loop/switch region; other site
526224000424	Predicted transcriptional regulators [Transcription]; Region: COG1695
526224000425	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
526224000426	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
526224000427	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
526224000428	dimerization domain swap beta strand [polypeptide binding]; other site
526224000429	regulatory protein interface [polypeptide binding]; other site
526224000430	active site
526224000431	regulatory phosphorylation site [posttranslational modification]; other site
526224000432	GntP family permease; Region: GntP_permease; pfam02447
526224000433	fructuronate transporter; Provisional; Region: PRK10034; cl15264
526224000434	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
526224000435	trimer interface [polypeptide binding]; other site
526224000436	active site
526224000437	chromosome segregation protein; Provisional; Region: PRK02224
526224000438	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
526224000439	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
526224000440	AAA domain; Region: AAA_13; pfam13166
526224000441	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
526224000442	Sulfatase; Region: Sulfatase; cl17466
526224000443	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
526224000444	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
526224000445	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
526224000446	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
526224000447	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224000448	dimer interface [polypeptide binding]; other site
526224000449	conserved gate region; other site
526224000450	putative PBP binding loops; other site
526224000451	ABC-ATPase subunit interface; other site
526224000452	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
526224000453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224000454	dimer interface [polypeptide binding]; other site
526224000455	conserved gate region; other site
526224000456	putative PBP binding loops; other site
526224000457	ABC-ATPase subunit interface; other site
526224000458	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
526224000459	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
526224000460	Walker A/P-loop; other site
526224000461	ATP binding site [chemical binding]; other site
526224000462	Q-loop/lid; other site
526224000463	ABC transporter signature motif; other site
526224000464	Walker B; other site
526224000465	D-loop; other site
526224000466	H-loop/switch region; other site
526224000467	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
526224000468	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
526224000469	Walker A/P-loop; other site
526224000470	ATP binding site [chemical binding]; other site
526224000471	Q-loop/lid; other site
526224000472	ABC transporter signature motif; other site
526224000473	Walker B; other site
526224000474	D-loop; other site
526224000475	H-loop/switch region; other site
526224000476	Transcriptional regulators [Transcription]; Region: PurR; COG1609
526224000477	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
526224000478	DNA binding site [nucleotide binding]
526224000479	domain linker motif; other site
526224000480	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
526224000481	ligand binding site [chemical binding]; other site
526224000482	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
526224000483	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
526224000484	catalytic residue [active]
526224000485	Protein of unknown function (DUF327); Region: DUF327; pfam03885
526224000486	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
526224000487	Glycoprotease family; Region: Peptidase_M22; pfam00814
526224000488	Cache domain; Region: Cache_1; pfam02743
526224000489	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224000490	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224000491	dimer interface [polypeptide binding]; other site
526224000492	putative CheW interface [polypeptide binding]; other site
526224000493	TPR repeat; Region: TPR_11; pfam13414
526224000494	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000495	binding surface
526224000496	TPR motif; other site
526224000497	TPR repeat; Region: TPR_11; pfam13414
526224000498	TPR repeat; Region: TPR_11; pfam13414
526224000499	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000500	binding surface
526224000501	TPR repeat; Region: TPR_11; pfam13414
526224000502	TPR motif; other site
526224000503	TPR repeat; Region: TPR_11; pfam13414
526224000504	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000505	binding surface
526224000506	TPR motif; other site
526224000507	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
526224000508	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
526224000509	folate binding site [chemical binding]; other site
526224000510	NADP+ binding site [chemical binding]; other site
526224000511	thymidylate synthase; Reviewed; Region: thyA; PRK01827
526224000512	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
526224000513	dimerization interface [polypeptide binding]; other site
526224000514	active site
526224000515	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
526224000516	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
526224000517	metal binding site [ion binding]; metal-binding site
526224000518	dimer interface [polypeptide binding]; other site
526224000519	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
526224000520	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
526224000521	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
526224000522	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
526224000523	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
526224000524	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
526224000525	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
526224000526	Recombination protein O N terminal; Region: RecO_N; pfam11967
526224000527	Recombination protein O C terminal; Region: RecO_C; pfam02565
526224000528	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
526224000529	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224000530	motif II; other site
526224000531	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
526224000532	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
526224000533	Protein of unknown function (DUF342); Region: DUF342; pfam03961
526224000534	RNA polymerase sigma factor WhiG; Reviewed; Region: PRK06288
526224000535	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224000536	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
526224000537	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224000538	DNA binding residues [nucleotide binding]
526224000539	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
526224000540	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
526224000541	P-loop; other site
526224000542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224000543	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
526224000544	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
526224000545	Walker A/P-loop; other site
526224000546	ATP binding site [chemical binding]; other site
526224000547	flagellar biosynthetic protein FlhF; Region: FlhF; TIGR03499
526224000548	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
526224000549	FHIPEP family; Region: FHIPEP; pfam00771
526224000550	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
526224000551	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
526224000552	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
526224000553	Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987
526224000554	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
526224000555	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
526224000556	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
526224000557	Coenzyme A binding pocket [chemical binding]; other site
526224000558	META domain; Region: META; pfam03724
526224000559	META domain; Region: META; cl01245
526224000560	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
526224000561	Transglycosylase; Region: Transgly; pfam00912
526224000562	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
526224000563	TraB family; Region: TraB; cl12050
526224000564	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000565	binding surface
526224000566	TPR motif; other site
526224000567	TPR repeat; Region: TPR_11; pfam13414
526224000568	TPR repeat; Region: TPR_11; pfam13414
526224000569	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000570	binding surface
526224000571	TPR motif; other site
526224000572	TPR repeat; Region: TPR_11; pfam13414
526224000573	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224000574	binding surface
526224000575	TPR motif; other site
526224000576	TPR repeat; Region: TPR_11; pfam13414
526224000577	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
526224000578	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
526224000579	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
526224000580	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
526224000581	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
526224000582	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
526224000583	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
526224000584	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
526224000585	Bacitracin resistance protein BacA; Region: BacA; pfam02673
526224000586	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
526224000587	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
526224000588	anti sigma factor interaction site; other site
526224000589	regulatory phosphorylation site [posttranslational modification]; other site
526224000590	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
526224000591	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
526224000592	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224000593	Protein export membrane protein; Region: SecD_SecF; cl14618
526224000594	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
526224000595	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
526224000596	ring oligomerisation interface [polypeptide binding]; other site
526224000597	ATP/Mg binding site [chemical binding]; other site
526224000598	stacking interactions; other site
526224000599	hinge regions; other site
526224000600	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
526224000601	recombination and repair protein; Provisional; Region: PRK10869
526224000602	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
526224000603	Permease; Region: Permease; pfam02405
526224000604	replicative DNA helicase; Region: DnaB; TIGR00665
526224000605	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
526224000606	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
526224000607	Walker A motif; other site
526224000608	ATP binding site [chemical binding]; other site
526224000609	Walker B motif; other site
526224000610	DNA binding loops [nucleotide binding]
526224000611	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
526224000612	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
526224000613	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
526224000614	Flavodoxin domain; Region: Flavodoxin_3; pfam12641
526224000615	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
526224000616	active site
526224000617	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
526224000618	nucleotide binding site/active site [active]
526224000619	HIT family signature motif; other site
526224000620	catalytic residue [active]
526224000621	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
526224000622	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
526224000623	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
526224000624	Serine hydrolase (FSH1); Region: FSH1; pfam03959
526224000625	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224000626	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224000627	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224000628	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
526224000629	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
526224000630	Protein of unknown function DUF58; Region: DUF58; pfam01882
526224000631	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
526224000632	metal ion-dependent adhesion site (MIDAS); other site
526224000633	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224000634	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000635	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000636	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000637	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000638	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000639	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000640	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000641	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
526224000642	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
526224000643	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
526224000644	heme-binding site [chemical binding]; other site
526224000645	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
526224000646	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
526224000647	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
526224000648	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
526224000649	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
526224000650	substrate binding site [chemical binding]; other site
526224000651	oxyanion hole (OAH) forming residues; other site
526224000652	trimer interface [polypeptide binding]; other site
526224000653	putative acyltransferase; Provisional; Region: PRK05790
526224000654	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
526224000655	dimer interface [polypeptide binding]; other site
526224000656	active site
526224000657	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
526224000658	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224000659	ATP binding site [chemical binding]; other site
526224000660	Mg2+ binding site [ion binding]; other site
526224000661	G-X-G motif; other site
526224000662	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
526224000663	ATP binding site [chemical binding]; other site
526224000664	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
526224000665	amidophosphoribosyltransferase; Provisional; Region: PRK05793
526224000666	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
526224000667	active site
526224000668	tetramer interface [polypeptide binding]; other site
526224000669	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224000670	active site
526224000671	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000672	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000673	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000674	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000675	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000676	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000677	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000678	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000679	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000680	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000681	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000682	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000683	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224000684	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224000685	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
526224000686	Fe-S cluster binding site [ion binding]; other site
526224000687	active site
526224000688	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224000689	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000690	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000691	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000692	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224000693	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
526224000694	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
526224000695	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
526224000696	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
526224000697	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
526224000698	30S subunit binding site; other site
526224000699	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224000700	active site
526224000701	phosphorylation site [posttranslational modification]
526224000702	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
526224000703	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
526224000704	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
526224000705	Hpr binding site; other site
526224000706	active site
526224000707	homohexamer subunit interaction site [polypeptide binding]; other site
526224000708	MraW methylase family; Region: Methyltransf_5; cl17771
526224000709	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
526224000710	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
526224000711	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
526224000712	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
526224000713	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
526224000714	PYR/PP interface [polypeptide binding]; other site
526224000715	dimer interface [polypeptide binding]; other site
526224000716	TPP binding site [chemical binding]; other site
526224000717	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
526224000718	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
526224000719	transketolase; Reviewed; Region: PRK05899
526224000720	TPP-binding site [chemical binding]; other site
526224000721	dimer interface [polypeptide binding]; other site
526224000722	Cache domain; Region: Cache_1; pfam02743
526224000723	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224000724	dimer interface [polypeptide binding]; other site
526224000725	putative CheW interface [polypeptide binding]; other site
526224000726	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
526224000727	GIY-YIG motif/motif A; other site
526224000728	putative active site [active]
526224000729	putative metal binding site [ion binding]; other site
526224000730	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224000731	active site
526224000732	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
526224000733	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
526224000734	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
526224000735	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
526224000736	Coenzyme A binding pocket [chemical binding]; other site
526224000737	Probable beta-xylosidase; Provisional; Region: PLN03080
526224000738	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
526224000739	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
526224000740	Transcriptional regulators [Transcription]; Region: PurR; COG1609
526224000741	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
526224000742	DNA binding site [nucleotide binding]
526224000743	domain linker motif; other site
526224000744	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
526224000745	dimerization interface [polypeptide binding]; other site
526224000746	ligand binding site [chemical binding]; other site
526224000747	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
526224000748	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000749	active site turn [active]
526224000750	phosphorylation site [posttranslational modification]
526224000751	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
526224000752	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
526224000753	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
526224000754	substrate binding [chemical binding]; other site
526224000755	active site
526224000756	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
526224000757	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
526224000758	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
526224000759	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
526224000760	glycogen synthase; Provisional; Region: glgA; PRK00654
526224000761	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
526224000762	ADP-binding pocket [chemical binding]; other site
526224000763	homodimer interface [polypeptide binding]; other site
526224000764	intracellular protease, PfpI family; Region: PfpI; TIGR01382
526224000765	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
526224000766	conserved cys residue [active]
526224000767	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224000768	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
526224000769	active site
526224000770	motif I; other site
526224000771	motif II; other site
526224000772	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224000773	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224000774	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
526224000775	active site
526224000776	motif I; other site
526224000777	motif II; other site
526224000778	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
526224000779	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK02862
526224000780	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
526224000781	ligand binding site; other site
526224000782	oligomer interface; other site
526224000783	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
526224000784	dimer interface [polypeptide binding]; other site
526224000785	N-terminal domain interface [polypeptide binding]; other site
526224000786	sulfate 1 binding site; other site
526224000787	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224000788	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
526224000789	RNA binding surface [nucleotide binding]; other site
526224000790	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
526224000791	active site
526224000792	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224000793	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
526224000794	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224000795	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
526224000796	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224000797	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224000798	homodimer interface [polypeptide binding]; other site
526224000799	catalytic residue [active]
526224000800	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
526224000801	YheO-like PAS domain; Region: PAS_6; pfam08348
526224000802	HTH domain; Region: HTH_22; pfam13309
526224000803	Domain of unknown function (DUF4253); Region: DUF4253; pfam14062
526224000804	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224000805	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224000806	peptide binding site [polypeptide binding]; other site
526224000807	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
526224000808	active site
526224000809	NTP binding site [chemical binding]; other site
526224000810	metal binding triad [ion binding]; metal-binding site
526224000811	antibiotic binding site [chemical binding]; other site
526224000812	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
526224000813	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
526224000814	propionate/acetate kinase; Provisional; Region: PRK12379
526224000815	Peptidase M30; Region: Peptidase_M30; pfam10460
526224000816	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224000817	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
526224000818	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
526224000819	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
526224000820	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
526224000821	NAD binding site [chemical binding]; other site
526224000822	substrate binding site [chemical binding]; other site
526224000823	homodimer interface [polypeptide binding]; other site
526224000824	active site
526224000825	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
526224000826	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
526224000827	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
526224000828	Walker A/P-loop; other site
526224000829	ATP binding site [chemical binding]; other site
526224000830	Q-loop/lid; other site
526224000831	ABC transporter signature motif; other site
526224000832	Walker B; other site
526224000833	D-loop; other site
526224000834	H-loop/switch region; other site
526224000835	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
526224000836	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
526224000837	Walker A/P-loop; other site
526224000838	ATP binding site [chemical binding]; other site
526224000839	Q-loop/lid; other site
526224000840	ABC transporter signature motif; other site
526224000841	Walker B; other site
526224000842	D-loop; other site
526224000843	H-loop/switch region; other site
526224000844	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
526224000845	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
526224000846	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224000847	active site
526224000848	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
526224000849	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
526224000850	putative tRNA-binding site [nucleotide binding]; other site
526224000851	B3/4 domain; Region: B3_4; pfam03483
526224000852	tRNA synthetase B5 domain; Region: B5; pfam03484
526224000853	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
526224000854	dimer interface [polypeptide binding]; other site
526224000855	motif 1; other site
526224000856	motif 3; other site
526224000857	motif 2; other site
526224000858	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
526224000859	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
526224000860	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
526224000861	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
526224000862	dimer interface [polypeptide binding]; other site
526224000863	motif 1; other site
526224000864	active site
526224000865	motif 2; other site
526224000866	motif 3; other site
526224000867	UGMP family protein; Validated; Region: PRK09604
526224000868	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
526224000869	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
526224000870	GAF domain; Region: GAF_3; pfam13492
526224000871	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
526224000872	GAF domain; Region: GAF; pfam01590
526224000873	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
526224000874	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
526224000875	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
526224000876	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
526224000877	FMN binding site [chemical binding]; other site
526224000878	active site
526224000879	catalytic residues [active]
526224000880	substrate binding site [chemical binding]; other site
526224000881	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
526224000882	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
526224000883	Walker A/P-loop; other site
526224000884	ATP binding site [chemical binding]; other site
526224000885	Q-loop/lid; other site
526224000886	ABC transporter signature motif; other site
526224000887	Walker B; other site
526224000888	D-loop; other site
526224000889	H-loop/switch region; other site
526224000890	TOBE domain; Region: TOBE; pfam03459
526224000891	Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264
526224000892	active site turn [active]
526224000893	phosphorylation site [posttranslational modification]
526224000894	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000895	active site turn [active]
526224000896	phosphorylation site [posttranslational modification]
526224000897	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000898	active site turn [active]
526224000899	phosphorylation site [posttranslational modification]
526224000900	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000901	active site turn [active]
526224000902	phosphorylation site [posttranslational modification]
526224000903	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
526224000904	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
526224000905	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224000906	active site turn [active]
526224000907	phosphorylation site [posttranslational modification]
526224000908	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
526224000909	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224000910	active site
526224000911	phosphorylation site [posttranslational modification]
526224000912	intermolecular recognition site; other site
526224000913	dimerization interface [polypeptide binding]; other site
526224000914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224000915	Walker A motif; other site
526224000916	ATP binding site [chemical binding]; other site
526224000917	Walker B motif; other site
526224000918	arginine finger; other site
526224000919	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
526224000920	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
526224000921	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
526224000922	dimer interface [polypeptide binding]; other site
526224000923	phosphorylation site [posttranslational modification]
526224000924	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224000925	ATP binding site [chemical binding]; other site
526224000926	Mg2+ binding site [ion binding]; other site
526224000927	G-X-G motif; other site
526224000928	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
526224000929	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
526224000930	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
526224000931	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
526224000932	Domain of unknown function (DUF4416); Region: DUF4416; pfam14385
526224000933	Cache domain; Region: Cache_1; pfam02743
526224000934	HAMP domain; Region: HAMP; pfam00672
526224000935	dimerization interface [polypeptide binding]; other site
526224000936	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224000937	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224000938	dimer interface [polypeptide binding]; other site
526224000939	putative CheW interface [polypeptide binding]; other site
526224000940	Hemerythrin; Region: Hemerythrin; cd12107
526224000941	Fe binding site [ion binding]; other site
526224000942	Cache domain; Region: Cache_1; pfam02743
526224000943	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
526224000944	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224000945	dimerization interface [polypeptide binding]; other site
526224000946	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224000947	dimer interface [polypeptide binding]; other site
526224000948	putative CheW interface [polypeptide binding]; other site
526224000949	Hemerythrin; Region: Hemerythrin; cd12107
526224000950	Fe binding site [ion binding]; other site
526224000951	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224000952	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224000953	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000954	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000955	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000956	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224000957	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224000958	FMN-binding domain; Region: FMN_bind; cl01081
526224000959	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
526224000960	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
526224000961	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
526224000962	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
526224000963	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
526224000964	tandem repeat interface [polypeptide binding]; other site
526224000965	oligomer interface [polypeptide binding]; other site
526224000966	active site residues [active]
526224000967	Predicted permeases [General function prediction only]; Region: COG0795
526224000968	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
526224000969	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
526224000970	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
526224000971	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
526224000972	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
526224000973	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
526224000974	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
526224000975	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224000976	dimer interface [polypeptide binding]; other site
526224000977	conserved gate region; other site
526224000978	putative PBP binding loops; other site
526224000979	ABC-ATPase subunit interface; other site
526224000980	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
526224000981	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224000982	dimer interface [polypeptide binding]; other site
526224000983	conserved gate region; other site
526224000984	ABC-ATPase subunit interface; other site
526224000985	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
526224000986	RNA/DNA hybrid binding site [nucleotide binding]; other site
526224000987	active site
526224000988	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
526224000989	DHH family; Region: DHH; pfam01368
526224000990	DHHA1 domain; Region: DHHA1; pfam02272
526224000991	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
526224000992	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
526224000993	putative CheA interaction surface; other site
526224000994	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
526224000995	MoaC family. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor...; Region: MoaC; cd00528
526224000996	trimer interface [polypeptide binding]; other site
526224000997	dimer interface [polypeptide binding]; other site
526224000998	putative active site [active]
526224000999	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
526224001000	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224001001	FeS/SAM binding site; other site
526224001002	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
526224001003	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
526224001004	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
526224001005	dimer interface [polypeptide binding]; other site
526224001006	putative functional site; other site
526224001007	putative MPT binding site; other site
526224001008	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
526224001009	XdhC Rossmann domain; Region: XdhC_C; pfam13478
526224001010	MOSC domain; Region: MOSC; pfam03473
526224001011	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
526224001012	MPT binding site; other site
526224001013	trimer interface [polypeptide binding]; other site
526224001014	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
526224001015	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
526224001016	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
526224001017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224001018	putative PBP binding loops; other site
526224001019	ABC-ATPase subunit interface; other site
526224001020	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
526224001021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224001022	Walker A/P-loop; other site
526224001023	ATP binding site [chemical binding]; other site
526224001024	Q-loop/lid; other site
526224001025	ABC transporter signature motif; other site
526224001026	Walker B; other site
526224001027	D-loop; other site
526224001028	H-loop/switch region; other site
526224001029	phenylhydantoinase; Validated; Region: PRK08323
526224001030	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
526224001031	tetramer interface [polypeptide binding]; other site
526224001032	active site
526224001033	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
526224001034	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
526224001035	active site
526224001036	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
526224001037	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
526224001038	ABC transporter; Region: ABC_tran_2; pfam12848
526224001039	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
526224001040	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
526224001041	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
526224001042	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
526224001043	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
526224001044	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
526224001045	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
526224001046	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
526224001047	peroxiredoxin; Region: AhpC; TIGR03137
526224001048	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
526224001049	dimer interface [polypeptide binding]; other site
526224001050	decamer (pentamer of dimers) interface [polypeptide binding]; other site
526224001051	catalytic triad [active]
526224001052	peroxidatic and resolving cysteines [active]
526224001053	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224001054	Zn2+ binding site [ion binding]; other site
526224001055	Mg2+ binding site [ion binding]; other site
526224001056	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
526224001057	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
526224001058	HflX GTPase family; Region: HflX; cd01878
526224001059	G1 box; other site
526224001060	GTP/Mg2+ binding site [chemical binding]; other site
526224001061	Switch I region; other site
526224001062	G2 box; other site
526224001063	G3 box; other site
526224001064	Switch II region; other site
526224001065	G4 box; other site
526224001066	G5 box; other site
526224001067	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224001068	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
526224001069	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
526224001070	Cache domain; Region: Cache_1; pfam02743
526224001071	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
526224001072	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224001073	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224001074	dimer interface [polypeptide binding]; other site
526224001075	putative CheW interface [polypeptide binding]; other site
526224001076	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224001077	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
526224001078	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
526224001079	active site
526224001080	catalytic residues [active]
526224001081	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
526224001082	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
526224001083	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
526224001084	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
526224001085	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
526224001086	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
526224001087	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224001088	catalytic residue [active]
526224001089	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001090	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224001091	binding surface
526224001092	TPR motif; other site
526224001093	TPR repeat; Region: TPR_11; pfam13414
526224001094	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001095	binding surface
526224001096	TPR motif; other site
526224001097	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224001098	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001099	binding surface
526224001100	TPR motif; other site
526224001101	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224001102	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224001103	Uncharacterized conserved protein [Function unknown]; Region: COG3391
526224001104	NHL repeat; Region: NHL; pfam01436
526224001105	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
526224001106	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
526224001107	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
526224001108	N-acetyl-D-glucosamine binding site [chemical binding]; other site
526224001109	catalytic residue [active]
526224001110	Flagellar biosynthesis/type III secretory pathway ATPase [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliI; COG1157
526224001111	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
526224001112	Walker A motif/ATP binding site; other site
526224001113	Walker B motif; other site
526224001114	flagellar assembly protein H; Validated; Region: fliH; PRK06669
526224001115	Flagellar assembly protein FliH; Region: FliH; pfam02108
526224001116	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
526224001117	FliG C-terminal domain; Region: FliG_C; pfam01706
526224001118	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
526224001119	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
526224001120	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
526224001121	Competence-damaged protein; Region: CinA; pfam02464
526224001122	Domain of unknown function (DUF1768); Region: DUF1768; cl01271
526224001123	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
526224001124	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
526224001125	Walker A/P-loop; other site
526224001126	ATP binding site [chemical binding]; other site
526224001127	Q-loop/lid; other site
526224001128	ABC transporter signature motif; other site
526224001129	Walker B; other site
526224001130	D-loop; other site
526224001131	H-loop/switch region; other site
526224001132	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
526224001133	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
526224001134	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
526224001135	Walker A/P-loop; other site
526224001136	ATP binding site [chemical binding]; other site
526224001137	Q-loop/lid; other site
526224001138	ABC transporter signature motif; other site
526224001139	Walker B; other site
526224001140	D-loop; other site
526224001141	H-loop/switch region; other site
526224001142	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
526224001143	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
526224001144	Coenzyme A binding pocket [chemical binding]; other site
526224001145	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
526224001146	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
526224001147	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
526224001148	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
526224001149	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
526224001150	GTP/Mg2+ binding site [chemical binding]; other site
526224001151	G4 box; other site
526224001152	G5 box; other site
526224001153	trmE is a tRNA modification GTPase; Region: trmE; cd04164
526224001154	G1 box; other site
526224001155	G1 box; other site
526224001156	GTP/Mg2+ binding site [chemical binding]; other site
526224001157	Switch I region; other site
526224001158	Switch I region; other site
526224001159	G2 box; other site
526224001160	G2 box; other site
526224001161	Switch II region; other site
526224001162	G3 box; other site
526224001163	G4 box; other site
526224001164	G5 box; other site
526224001165	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
526224001166	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
526224001167	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224001168	ligand binding site [chemical binding]; other site
526224001169	flexible hinge region; other site
526224001170	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224001171	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224001172	ligand binding site [chemical binding]; other site
526224001173	flexible hinge region; other site
526224001174	adenylosuccinate lyase; Provisional; Region: PRK07492
526224001175	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
526224001176	tetramer interface [polypeptide binding]; other site
526224001177	active site
526224001178	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
526224001179	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
526224001180	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
526224001181	tetramer interface [polypeptide binding]; other site
526224001182	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224001183	catalytic residue [active]
526224001184	Methyltransferase domain; Region: Methyltransf_23; pfam13489
526224001185	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224001186	S-adenosylmethionine binding site [chemical binding]; other site
526224001187	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
526224001188	NusA N-terminal domain; Region: NusA_N; pfam08529
526224001189	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
526224001190	RNA binding site [nucleotide binding]; other site
526224001191	homodimer interface [polypeptide binding]; other site
526224001192	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
526224001193	G-X-X-G motif; other site
526224001194	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
526224001195	G-X-X-G motif; other site
526224001196	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
526224001197	Sm and related proteins; Region: Sm_like; cl00259
526224001198	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
526224001199	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
526224001200	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
526224001201	putative active site [active]
526224001202	catalytic site [active]
526224001203	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
526224001204	putative active site [active]
526224001205	catalytic site [active]
526224001206	Cache domain; Region: Cache_1; pfam02743
526224001207	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
526224001208	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224001209	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224001210	dimer interface [polypeptide binding]; other site
526224001211	putative CheW interface [polypeptide binding]; other site
526224001212	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
526224001213	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
526224001214	Protein of unknown function (DUF342); Region: DUF342; pfam03961
526224001215	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
526224001216	Transcription elongation factor Elf1 like; Region: Elf1; cl02038
526224001217	Methyltransferase domain; Region: Methyltransf_23; pfam13489
526224001218	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224001219	S-adenosylmethionine binding site [chemical binding]; other site
526224001220	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
526224001221	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
526224001222	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
526224001223	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
526224001224	putative active site [active]
526224001225	substrate binding site [chemical binding]; other site
526224001226	putative cosubstrate binding site; other site
526224001227	catalytic site [active]
526224001228	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
526224001229	substrate binding site [chemical binding]; other site
526224001230	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001231	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001232	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001233	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001234	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001235	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001236	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001237	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001238	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
526224001239	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001240	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001241	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001242	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
526224001243	Predicted solute binding protein [General function prediction only]; Region: COG3889
526224001244	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224001245	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224001246	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
526224001247	YheO-like PAS domain; Region: PAS_6; pfam08348
526224001248	HTH domain; Region: HTH_22; pfam13309
526224001249	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
526224001250	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
526224001251	active site
526224001252	DNA binding site [nucleotide binding]
526224001253	Int/Topo IB signature motif; other site
526224001254	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
526224001255	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224001256	dimer interface [polypeptide binding]; other site
526224001257	conserved gate region; other site
526224001258	putative PBP binding loops; other site
526224001259	ABC-ATPase subunit interface; other site
526224001260	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
526224001261	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
526224001262	Walker A/P-loop; other site
526224001263	ATP binding site [chemical binding]; other site
526224001264	Q-loop/lid; other site
526224001265	ABC transporter signature motif; other site
526224001266	Walker B; other site
526224001267	D-loop; other site
526224001268	H-loop/switch region; other site
526224001269	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
526224001270	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224001271	substrate binding pocket [chemical binding]; other site
526224001272	membrane-bound complex binding site; other site
526224001273	hinge residues; other site
526224001274	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
526224001275	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224001276	membrane-bound complex binding site; other site
526224001277	hinge residues; other site
526224001278	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
526224001279	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
526224001280	UDP-N-acetylmuramate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: MurB; COG0812
526224001281	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
526224001282	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
526224001283	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
526224001284	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
526224001285	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
526224001286	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
526224001287	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
526224001288	active site
526224001289	homodimer interface [polypeptide binding]; other site
526224001290	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
526224001291	FOG: CBS domain [General function prediction only]; Region: COG0517
526224001292	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
526224001293	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
526224001294	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
526224001295	metal binding site [ion binding]; metal-binding site
526224001296	active site
526224001297	I-site; other site
526224001298	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
526224001299	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224001300	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
526224001301	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
526224001302	Amidinotransferase; Region: Amidinotransf; cl12043
526224001303	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
526224001304	EamA-like transporter family; Region: EamA; pfam00892
526224001305	EamA-like transporter family; Region: EamA; pfam00892
526224001306	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001307	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001308	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001309	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001310	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001311	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001312	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001313	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001314	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001315	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001316	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001317	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
526224001318	MgtE intracellular N domain; Region: MgtE_N; pfam03448
526224001319	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
526224001320	Divalent cation transporter; Region: MgtE; pfam01769
526224001321	P-loop containing region of AAA domain; Region: AAA_29; cl17516
526224001322	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
526224001323	LabA_like proteins; Region: LabA_like; cd06167
526224001324	putative metal binding site [ion binding]; other site
526224001325	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
526224001326	prephenate dehydrogenase; Validated; Region: PRK08507
526224001327	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
526224001328	RNB domain; Region: RNB; pfam00773
526224001329	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
526224001330	RNA binding site [nucleotide binding]; other site
526224001331	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
526224001332	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
526224001333	Catalytic site [active]
526224001334	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
526224001335	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
526224001336	dimer interface [polypeptide binding]; other site
526224001337	active site
526224001338	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001339	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001340	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001341	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
526224001342	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224001343	NAD(P) binding site [chemical binding]; other site
526224001344	active site
526224001345	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
526224001346	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
526224001347	dimer interface [polypeptide binding]; other site
526224001348	active site
526224001349	Predicted exporter [General function prediction only]; Region: COG4258
526224001350	Predicted exporter [General function prediction only]; Region: COG4258
526224001351	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
526224001352	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
526224001353	active site
526224001354	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
526224001355	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
526224001356	putative acyl-acceptor binding pocket; other site
526224001357	O-succinylbenzoate-CoA ligase; Region: menE; TIGR01923
526224001358	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
526224001359	AMP binding site [chemical binding]; other site
526224001360	active site
526224001361	acyl-activating enzyme (AAE) consensus motif; other site
526224001362	CoA binding site [chemical binding]; other site
526224001363	Phosphopantetheine attachment site; Region: PP-binding; cl09936
526224001364	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
526224001365	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
526224001366	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
526224001367	DNA binding residues [nucleotide binding]
526224001368	putative dimer interface [polypeptide binding]; other site
526224001369	Uncharacterized conserved protein [Function unknown]; Region: COG4925
526224001370	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224001371	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224001372	active site
526224001373	catalytic tetrad [active]
526224001374	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224001375	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224001376	active site
526224001377	catalytic tetrad [active]
526224001378	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224001379	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224001380	active site
526224001381	catalytic tetrad [active]
526224001382	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224001383	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
526224001384	Uncharacterized conserved protein [Function unknown]; Region: COG1262
526224001385	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
526224001386	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224001387	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
526224001388	Transcriptional regulator [Transcription]; Region: LysR; COG0583
526224001389	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
526224001390	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
526224001391	dimerization interface [polypeptide binding]; other site
526224001392	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
526224001393	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
526224001394	DNA binding residues [nucleotide binding]
526224001395	putative dimer interface [polypeptide binding]; other site
526224001396	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
526224001397	TRAM domain; Region: TRAM; cl01282
526224001398	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
526224001399	hypothetical protein; Provisional; Region: PRK01346
526224001400	Sterol carrier protein domain; Region: SCP2_2; pfam13530
526224001401	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
526224001402	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001403	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001404	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001405	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001406	gamma-glutamyl kinase; Provisional; Region: PRK05429
526224001407	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
526224001408	nucleotide binding site [chemical binding]; other site
526224001409	homotetrameric interface [polypeptide binding]; other site
526224001410	putative phosphate binding site [ion binding]; other site
526224001411	putative allosteric binding site; other site
526224001412	PUA domain; Region: PUA; pfam01472
526224001413	ADP-glucose phosphorylase; Region: PLN02643
526224001414	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
526224001415	nucleotide binding site/active site [active]
526224001416	HIT family signature motif; other site
526224001417	catalytic residue [active]
526224001418	Response regulator receiver domain; Region: Response_reg; pfam00072
526224001419	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224001420	active site
526224001421	phosphorylation site [posttranslational modification]
526224001422	intermolecular recognition site; other site
526224001423	dimerization interface [polypeptide binding]; other site
526224001424	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
526224001425	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
526224001426	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
526224001427	CoenzymeA binding site [chemical binding]; other site
526224001428	subunit interaction site [polypeptide binding]; other site
526224001429	PHB binding site; other site
526224001430	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
526224001431	Na2 binding site [ion binding]; other site
526224001432	putative substrate binding site 1 [chemical binding]; other site
526224001433	Na binding site 1 [ion binding]; other site
526224001434	putative substrate binding site 2 [chemical binding]; other site
526224001435	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
526224001436	pyruvate kinase; Provisional; Region: PRK05826
526224001437	domain interfaces; other site
526224001438	active site
526224001439	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
526224001440	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
526224001441	BCCT family transporter; Region: BCCT; cl00569
526224001442	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224001443	binding surface
526224001444	TPR motif; other site
526224001445	rarD protein; Region: rarD; TIGR00688
526224001446	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001447	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001448	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001449	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001450	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001451	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001452	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
526224001453	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
526224001454	active site
526224001455	FMN binding site [chemical binding]; other site
526224001456	substrate binding site [chemical binding]; other site
526224001457	homotetramer interface [polypeptide binding]; other site
526224001458	catalytic residue [active]
526224001459	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001460	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001461	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001462	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001463	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001464	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001465	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001466	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001467	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001468	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001469	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001470	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001471	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001472	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001473	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001474	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001475	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001476	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001477	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001478	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001479	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
526224001480	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
526224001481	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
526224001482	active site
526224001483	HIGH motif; other site
526224001484	dimer interface [polypeptide binding]; other site
526224001485	KMSKS motif; other site
526224001486	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
526224001487	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
526224001488	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
526224001489	active site
526224001490	Dehydroquinase class II; Region: DHquinase_II; pfam01220
526224001491	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
526224001492	trimer interface [polypeptide binding]; other site
526224001493	active site
526224001494	dimer interface [polypeptide binding]; other site
526224001495	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
526224001496	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
526224001497	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
526224001498	active site
526224001499	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
526224001500	YceG-like family; Region: YceG; pfam02618
526224001501	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
526224001502	dimerization interface [polypeptide binding]; other site
526224001503	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
526224001504	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
526224001505	dimer interface [polypeptide binding]; other site
526224001506	motif 1; other site
526224001507	active site
526224001508	motif 2; other site
526224001509	motif 3; other site
526224001510	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
526224001511	anticodon binding site; other site
526224001512	selenocysteine-specific elongation factor SelB; Region: selB; TIGR00475
526224001513	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
526224001514	G1 box; other site
526224001515	putative GEF interaction site [polypeptide binding]; other site
526224001516	GTP/Mg2+ binding site [chemical binding]; other site
526224001517	Switch I region; other site
526224001518	G2 box; other site
526224001519	G3 box; other site
526224001520	Switch II region; other site
526224001521	G4 box; other site
526224001522	G5 box; other site
526224001523	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
526224001524	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
526224001525	selenocysteine synthase; Provisional; Region: PRK04311
526224001526	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
526224001527	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
526224001528	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224001529	catalytic residue [active]
526224001530	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
526224001531	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
526224001532	active site
526224001533	(T/H)XGH motif; other site
526224001534	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
526224001535	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
526224001536	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
526224001537	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
526224001538	active site
526224001539	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
526224001540	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
526224001541	active site
526224001542	dimer interface [polypeptide binding]; other site
526224001543	Predicted helicase [General function prediction only]; Region: COG4889
526224001544	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
526224001545	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
526224001546	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
526224001547	oligomer interface [polypeptide binding]; other site
526224001548	active site
526224001549	metal binding site [ion binding]; metal-binding site
526224001550	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
526224001551	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224001552	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224001553	binding surface
526224001554	TPR motif; other site
526224001555	N-glycosylase/DNA lyase; Provisional; Region: PRK01229
526224001556	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
526224001557	minor groove reading motif; other site
526224001558	helix-hairpin-helix signature motif; other site
526224001559	active site
526224001560	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
526224001561	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
526224001562	active site
526224001563	metal binding site [ion binding]; metal-binding site
526224001564	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
526224001565	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
526224001566	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
526224001567	putative active site [active]
526224001568	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
526224001569	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
526224001570	zinc binding site [ion binding]; other site
526224001571	putative ligand binding site [chemical binding]; other site
526224001572	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
526224001573	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
526224001574	B12 binding site [chemical binding]; other site
526224001575	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224001576	FeS/SAM binding site; other site
526224001577	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
526224001578	classical (c) SDRs; Region: SDR_c; cd05233
526224001579	NAD(P) binding site [chemical binding]; other site
526224001580	active site
526224001581	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224001582	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224001583	Oxygen tolerance; Region: BatD; pfam13584
526224001584	MoxR-like ATPases [General function prediction only]; Region: COG0714
526224001585	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224001586	Walker A motif; other site
526224001587	ATP binding site [chemical binding]; other site
526224001588	Walker B motif; other site
526224001589	arginine finger; other site
526224001590	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
526224001591	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
526224001592	tetramer interface [polypeptide binding]; other site
526224001593	heme binding pocket [chemical binding]; other site
526224001594	NADPH binding site [chemical binding]; other site
526224001595	aspartate aminotransferase; Provisional; Region: PRK07568
526224001596	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224001597	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224001598	homodimer interface [polypeptide binding]; other site
526224001599	catalytic residue [active]
526224001600	adenylate kinase; Reviewed; Region: adk; PRK00279
526224001601	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
526224001602	AMP-binding site [chemical binding]; other site
526224001603	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
526224001604	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
526224001605	putative RNA binding site [nucleotide binding]; other site
526224001606	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001607	binding surface
526224001608	TPR motif; other site
526224001609	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001610	binding surface
526224001611	TPR motif; other site
526224001612	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001613	TPR motif; other site
526224001614	binding surface
526224001615	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001616	binding surface
526224001617	TPR motif; other site
526224001618	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001619	TPR motif; other site
526224001620	binding surface
526224001621	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001622	binding surface
526224001623	TPR motif; other site
526224001624	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
526224001625	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
526224001626	Ligand binding site; other site
526224001627	Putative Catalytic site; other site
526224001628	DXD motif; other site
526224001629	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
526224001630	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
526224001631	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224001632	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
526224001633	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
526224001634	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
526224001635	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
526224001636	Walker A/P-loop; other site
526224001637	ATP binding site [chemical binding]; other site
526224001638	Q-loop/lid; other site
526224001639	ABC transporter signature motif; other site
526224001640	Walker B; other site
526224001641	D-loop; other site
526224001642	H-loop/switch region; other site
526224001643	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
526224001644	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
526224001645	ABC-ATPase subunit  interface; other site
526224001646	dimer interface [polypeptide binding]; other site
526224001647	putative PBP binding regions; other site
526224001648	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
526224001649	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
526224001650	intersubunit interface [polypeptide binding]; other site
526224001651	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
526224001652	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
526224001653	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
526224001654	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
526224001655	heterotetramer interface [polypeptide binding]; other site
526224001656	active site pocket [active]
526224001657	cleavage site
526224001658	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
526224001659	feedback inhibition sensing region; other site
526224001660	homohexameric interface [polypeptide binding]; other site
526224001661	nucleotide binding site [chemical binding]; other site
526224001662	N-acetyl-L-glutamate binding site [chemical binding]; other site
526224001663	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
526224001664	acetylornithine aminotransferase; Provisional; Region: PRK02627
526224001665	inhibitor-cofactor binding pocket; inhibition site
526224001666	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224001667	catalytic residue [active]
526224001668	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
526224001669	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224001670	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
526224001671	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
526224001672	Coenzyme A binding pocket [chemical binding]; other site
526224001673	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
526224001674	ferredoxin; Provisional; Region: PRK08764
526224001675	Putative Fe-S cluster; Region: FeS; cl17515
526224001676	Rnf-Nqr subunit, membrane protein; Region: Rnf-Nqr; cl00597
526224001677	electron transport complex RsxE subunit; Provisional; Region: PRK12405
526224001678	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224001679	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224001680	dimer interface [polypeptide binding]; other site
526224001681	putative CheW interface [polypeptide binding]; other site
526224001682	Predicted membrane protein [Function unknown]; Region: COG2364
526224001683	GTPase RsgA; Reviewed; Region: PRK01889
526224001684	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
526224001685	RNA binding site [nucleotide binding]; other site
526224001686	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
526224001687	GTPase/Zn-binding domain interface [polypeptide binding]; other site
526224001688	GTP/Mg2+ binding site [chemical binding]; other site
526224001689	G4 box; other site
526224001690	G5 box; other site
526224001691	G1 box; other site
526224001692	Switch I region; other site
526224001693	G2 box; other site
526224001694	G3 box; other site
526224001695	Switch II region; other site
526224001696	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
526224001697	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
526224001698	Soluble P-type ATPase [General function prediction only]; Region: COG4087
526224001699	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
526224001700	dimerization interface [polypeptide binding]; other site
526224001701	putative DNA binding site [nucleotide binding]; other site
526224001702	putative Zn2+ binding site [ion binding]; other site
526224001703	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
526224001704	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224001705	S-adenosylmethionine binding site [chemical binding]; other site
526224001706	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
526224001707	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
526224001708	putative catalytic cysteine [active]
526224001709	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
526224001710	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
526224001711	P-loop; other site
526224001712	Magnesium ion binding site [ion binding]; other site
526224001713	transport-energizing ATPase, TRC40/GET3/ArsA family; Region: GET3_arsA_TRC40; TIGR00345
526224001714	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
526224001715	Magnesium ion binding site [ion binding]; other site
526224001716	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
526224001717	ParB-like nuclease domain; Region: ParB; smart00470
526224001718	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
526224001719	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
526224001720	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
526224001721	putative active site [active]
526224001722	metal binding site [ion binding]; metal-binding site
526224001723	homodimer binding site [polypeptide binding]; other site
526224001724	phosphodiesterase; Provisional; Region: PRK12704
526224001725	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224001726	Zn2+ binding site [ion binding]; other site
526224001727	Mg2+ binding site [ion binding]; other site
526224001728	Rubrerythrin [Energy production and conversion]; Region: COG1592
526224001729	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
526224001730	binuclear metal center [ion binding]; other site
526224001731	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
526224001732	iron binding site [ion binding]; other site
526224001733	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
526224001734	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
526224001735	active site
526224001736	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
526224001737	HEAT repeats; Region: HEAT_2; pfam13646
526224001738	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
526224001739	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
526224001740	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224001741	active site
526224001742	motif I; other site
526224001743	motif II; other site
526224001744	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224001745	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
526224001746	Major Facilitator Superfamily; Region: MFS_1; pfam07690
526224001747	putative substrate translocation pore; other site
526224001748	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
526224001749	EamA-like transporter family; Region: EamA; pfam00892
526224001750	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
526224001751	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
526224001752	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
526224001753	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
526224001754	AAA domain; Region: AAA_21; pfam13304
526224001755	AAA domain; Region: AAA_21; pfam13304
526224001756	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
526224001757	Walker B; other site
526224001758	D-loop; other site
526224001759	H-loop/switch region; other site
526224001760	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224001761	active site residue [active]
526224001762	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
526224001763	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
526224001764	active site
526224001765	metal binding site [ion binding]; metal-binding site
526224001766	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
526224001767	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224001768	putative efflux protein, MATE family; Region: matE; TIGR00797
526224001769	potential frameshift: common BLAST hit: gi|225619945|ref|YP_002721202.1|  methyl-accepting protein
526224001770	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224001771	dimer interface [polypeptide binding]; other site
526224001772	putative CheW interface [polypeptide binding]; other site
526224001773	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224001774	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224001775	peptide binding site [polypeptide binding]; other site
526224001776	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224001777	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224001778	peptide binding site [polypeptide binding]; other site
526224001779	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
526224001780	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224001781	active site
526224001782	phosphorylation site [posttranslational modification]
526224001783	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
526224001784	active site
526224001785	P-loop; other site
526224001786	phosphorylation site [posttranslational modification]
526224001787	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
526224001788	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
526224001789	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
526224001790	putative substrate binding site [chemical binding]; other site
526224001791	putative ATP binding site [chemical binding]; other site
526224001792	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
526224001793	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
526224001794	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
526224001795	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
526224001796	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
526224001797	metal binding site [ion binding]; metal-binding site
526224001798	dimer interface [polypeptide binding]; other site
526224001799	threonine synthase; Reviewed; Region: PRK06721
526224001800	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
526224001801	homodimer interface [polypeptide binding]; other site
526224001802	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224001803	catalytic residue [active]
526224001804	homoserine kinase; Provisional; Region: PRK01212
526224001805	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
526224001806	Domain of unknown function (DUF1980); Region: DUF1980; cl01492
526224001807	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
526224001808	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
526224001809	ABC-ATPase subunit  interface; other site
526224001810	dimer interface [polypeptide binding]; other site
526224001811	putative PBP binding regions; other site
526224001812	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
526224001813	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
526224001814	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
526224001815	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
526224001816	intersubunit interface [polypeptide binding]; other site
526224001817	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
526224001818	SirA-like protein; Region: SirA; pfam01206
526224001819	CPxP  motif; other site
526224001820	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224001821	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224001822	peptide binding site [polypeptide binding]; other site
526224001823	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
526224001824	MarR family; Region: MarR_2; pfam12802
526224001825	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224001826	binding surface
526224001827	TPR motif; other site
526224001828	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224001829	binding surface
526224001830	TPR motif; other site
526224001831	TPR repeat; Region: TPR_11; pfam13414
526224001832	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
526224001833	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
526224001834	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
526224001835	active site
526224001836	catalytic residues [active]
526224001837	metal binding site [ion binding]; metal-binding site
526224001838	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
526224001839	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224001840	motif II; other site
526224001841	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
526224001842	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224001843	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224001844	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224001845	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
526224001846	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
526224001847	metal binding site [ion binding]; metal-binding site
526224001848	active site
526224001849	I-site; other site
526224001850	potassium/proton antiporter; Reviewed; Region: PRK05326
526224001851	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
526224001852	TrkA-C domain; Region: TrkA_C; pfam02080
526224001853	TrkA-C domain; Region: TrkA_C; pfam02080
526224001854	flagellar hook-associated protein FlgL; Validated; Region: PRK06663
526224001855	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
526224001856	FliW protein; Region: FliW; cl00740
526224001857	Global regulator protein family; Region: CsrA; pfam02599
526224001858	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
526224001859	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
526224001860	benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260
526224001861	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
526224001862	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
526224001863	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224001864	catalytic residue [active]
526224001865	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
526224001866	nucleotide binding site [chemical binding]; other site
526224001867	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
526224001868	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
526224001869	DEAD-like helicases superfamily; Region: DEXDc; smart00487
526224001870	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224001871	ATP binding site [chemical binding]; other site
526224001872	putative Mg++ binding site [ion binding]; other site
526224001873	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224001874	nucleotide binding region [chemical binding]; other site
526224001875	ATP-binding site [chemical binding]; other site
526224001876	TRCF domain; Region: TRCF; pfam03461
526224001877	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001878	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001879	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001880	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
526224001881	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001882	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001883	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001884	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001885	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001886	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001887	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001888	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001889	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224001890	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224001891	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224001892	flagellin; Provisional; Region: PRK12804
526224001893	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
526224001894	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
526224001895	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
526224001896	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224001897	DNA binding residues [nucleotide binding]
526224001898	Protein of unknown function (DUF563); Region: DUF563; pfam04577
526224001899	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
526224001900	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
526224001901	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
526224001902	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
526224001903	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
526224001904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
526224001905	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cl00540
526224001906	tetramerization interface [polypeptide binding]; other site
526224001907	active site
526224001908	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
526224001909	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
526224001910	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
526224001911	iron-sulfur cluster [ion binding]; other site
526224001912	[2Fe-2S] cluster binding site [ion binding]; other site
526224001913	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
526224001914	hydrophobic ligand binding site; other site
526224001915	Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors; Region: STAS; cl00604
526224001916	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
526224001917	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
526224001918	active site
526224001919	Riboflavin kinase; Region: Flavokinase; smart00904
526224001920	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
526224001921	16S/18S rRNA binding site [nucleotide binding]; other site
526224001922	S13e-L30e interaction site [polypeptide binding]; other site
526224001923	25S rRNA binding site [nucleotide binding]; other site
526224001924	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
526224001925	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
526224001926	RNase E interface [polypeptide binding]; other site
526224001927	trimer interface [polypeptide binding]; other site
526224001928	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
526224001929	RNase E interface [polypeptide binding]; other site
526224001930	trimer interface [polypeptide binding]; other site
526224001931	active site
526224001932	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
526224001933	putative nucleic acid binding region [nucleotide binding]; other site
526224001934	G-X-X-G motif; other site
526224001935	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
526224001936	RNA binding site [nucleotide binding]; other site
526224001937	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
526224001938	anti sigma factor interaction site; other site
526224001939	regulatory phosphorylation site [posttranslational modification]; other site
526224001940	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
526224001941	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
526224001942	GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522
526224001943	Probable Catalytic site; other site
526224001944	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
526224001945	Uncharacterized conserved protein [Function unknown]; Region: COG0398
526224001946	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
526224001947	Uncharacterized conserved protein [Function unknown]; Region: COG0398
526224001948	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
526224001949	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
526224001950	Protein of unknown function (DUF523); Region: DUF523; cl00733
526224001951	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
526224001952	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
526224001953	Walker A/P-loop; other site
526224001954	ATP binding site [chemical binding]; other site
526224001955	Q-loop/lid; other site
526224001956	ABC transporter signature motif; other site
526224001957	Walker B; other site
526224001958	D-loop; other site
526224001959	H-loop/switch region; other site
526224001960	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
526224001961	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
526224001962	Walker A/P-loop; other site
526224001963	ATP binding site [chemical binding]; other site
526224001964	Q-loop/lid; other site
526224001965	ABC transporter signature motif; other site
526224001966	Walker B; other site
526224001967	D-loop; other site
526224001968	H-loop/switch region; other site
526224001969	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
526224001970	Uncharacterized N-terminal domain of the transcription elongation factor GreA [Function unknown]; Region: COG1747
526224001971	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224001972	binding surface
526224001973	TPR motif; other site
526224001974	imidazolonepropionase; Validated; Region: PRK09356
526224001975	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
526224001976	active site
526224001977	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
526224001978	putative hydrolase; Validated; Region: PRK09248
526224001979	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
526224001980	active site
526224001981	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
526224001982	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
526224001983	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
526224001984	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
526224001985	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224001986	4Fe-4S single cluster domain; Region: Fer4_14; pfam13394
526224001987	FeS/SAM binding site; other site
526224001988	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
526224001989	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
526224001990	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224001991	substrate binding site [chemical binding]; other site
526224001992	ATP binding site [chemical binding]; other site
526224001993	recombination protein RecR; Reviewed; Region: recR; PRK00076
526224001994	RecR protein; Region: RecR; pfam02132
526224001995	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
526224001996	putative active site [active]
526224001997	putative metal-binding site [ion binding]; other site
526224001998	tetramer interface [polypeptide binding]; other site
526224001999	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; pfam02575
526224002000	Curli production assembly/transport component CsgG; Region: CsgG; cl17434
526224002001	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
526224002002	Septum formation initiator; Region: DivIC; cl17659
526224002003	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224002004	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
526224002005	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
526224002006	NADH(P)-binding; Region: NAD_binding_10; pfam13460
526224002007	NAD binding site [chemical binding]; other site
526224002008	substrate binding site [chemical binding]; other site
526224002009	putative active site [active]
526224002010	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
526224002011	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cd00296
526224002012	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
526224002013	ADP-ribose binding site [chemical binding]; other site
526224002014	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
526224002015	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
526224002016	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
526224002017	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
526224002018	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
526224002019	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
526224002020	Rrf2 family protein; Region: rrf2_super; TIGR00738
526224002021	Transcriptional regulator; Region: Rrf2; pfam02082
526224002022	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
526224002023	methionine cluster; other site
526224002024	active site
526224002025	phosphorylation site [posttranslational modification]
526224002026	metal binding site [ion binding]; metal-binding site
526224002027	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
526224002028	beta-galactosidase; Region: BGL; TIGR03356
526224002029	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
526224002030	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
526224002031	Uncharacterized conserved protein [Function unknown]; Region: COG3589
526224002032	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
526224002033	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
526224002034	active site
526224002035	P-loop; other site
526224002036	phosphorylation site [posttranslational modification]
526224002037	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
526224002038	HTH domain; Region: HTH_11; pfam08279
526224002039	Mga helix-turn-helix domain; Region: Mga; pfam05043
526224002040	PRD domain; Region: PRD; pfam00874
526224002041	PRD domain; Region: PRD; pfam00874
526224002042	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
526224002043	active site
526224002044	P-loop; other site
526224002045	phosphorylation site [posttranslational modification]
526224002046	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
526224002047	active site
526224002048	phosphorylation site [posttranslational modification]
526224002049	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
526224002050	dimerization domain swap beta strand [polypeptide binding]; other site
526224002051	regulatory protein interface [polypeptide binding]; other site
526224002052	active site
526224002053	regulatory phosphorylation site [posttranslational modification]; other site
526224002054	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
526224002055	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
526224002056	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224002057	catalytic residue [active]
526224002058	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
526224002059	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
526224002060	trimerization site [polypeptide binding]; other site
526224002061	active site
526224002062	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
526224002063	NifU-like domain; Region: NifU; pfam01106
526224002064	monogalactosyldiacylglycerol synthase; Region: PLN02605
526224002065	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
526224002066	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
526224002067	monogalactosyldiacylglycerol synthase; Region: PLN02605
526224002068	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
526224002069	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
526224002070	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
526224002071	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
526224002072	RNA binding site [nucleotide binding]; other site
526224002073	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
526224002074	RNA binding site [nucleotide binding]; other site
526224002075	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
526224002076	RNA binding site [nucleotide binding]; other site
526224002077	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
526224002078	RNA binding site [nucleotide binding]; other site
526224002079	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
526224002080	RNA binding site [nucleotide binding]; other site
526224002081	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
526224002082	RNA binding site [nucleotide binding]; other site
526224002083	cytidylate kinase; Provisional; Region: cmk; PRK00023
526224002084	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
526224002085	CMP-binding site; other site
526224002086	The sites determining sugar specificity; other site
526224002087	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224002088	active site
526224002089	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
526224002090	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
526224002091	nucleotide binding site/active site [active]
526224002092	HIT family signature motif; other site
526224002093	catalytic residue [active]
526224002094	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224002095	active site
526224002096	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
526224002097	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
526224002098	Ligand binding site; other site
526224002099	metal-binding site
526224002100	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224002101	active site
526224002102	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
526224002103	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
526224002104	Ligand binding site; other site
526224002105	metal-binding site
526224002106	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224002107	active site
526224002108	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224002109	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
526224002110	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
526224002111	Ligand binding site; other site
526224002112	metal-binding site
526224002113	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
526224002114	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
526224002115	Ligand binding site; other site
526224002116	metal-binding site
526224002117	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224002118	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224002119	active site
526224002120	catalytic tetrad [active]
526224002121	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
526224002122	Mechanosensitive ion channel; Region: MS_channel; pfam00924
526224002123	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
526224002124	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
526224002125	active site
526224002126	dimer interface [polypeptide binding]; other site
526224002127	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
526224002128	Domain of unknown function DUF21; Region: DUF21; pfam01595
526224002129	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
526224002130	Transporter associated domain; Region: CorC_HlyC; smart01091
526224002131	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
526224002132	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224002133	non-specific DNA binding site [nucleotide binding]; other site
526224002134	salt bridge; other site
526224002135	sequence-specific DNA binding site [nucleotide binding]; other site
526224002136	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
526224002137	G1 box; other site
526224002138	GTP/Mg2+ binding site [chemical binding]; other site
526224002139	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
526224002140	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
526224002141	ATP binding site [chemical binding]; other site
526224002142	active site
526224002143	substrate binding site [chemical binding]; other site
526224002144	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
526224002145	Zn-ribbon containing protein [General function prediction only]; Region: COG3364
526224002146	FlgD Ig-like domain; Region: FlgD_ig; pfam13860
526224002147	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224002148	active site
526224002149	phosphorylation site [posttranslational modification]
526224002150	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
526224002151	Putative zinc ribbon domain; Region: DUF164; pfam02591
526224002152	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
526224002153	elongation factor G; Reviewed; Region: PRK12740
526224002154	G1 box; other site
526224002155	putative GEF interaction site [polypeptide binding]; other site
526224002156	GTP/Mg2+ binding site [chemical binding]; other site
526224002157	Switch I region; other site
526224002158	G2 box; other site
526224002159	G3 box; other site
526224002160	Switch II region; other site
526224002161	G4 box; other site
526224002162	G5 box; other site
526224002163	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
526224002164	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
526224002165	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
526224002166	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002167	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224002168	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
526224002169	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
526224002170	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
526224002171	G1 box; other site
526224002172	GTP/Mg2+ binding site [chemical binding]; other site
526224002173	Switch I region; other site
526224002174	G2 box; other site
526224002175	G3 box; other site
526224002176	Switch II region; other site
526224002177	G4 box; other site
526224002178	G5 box; other site
526224002179	Nucleoside recognition; Region: Gate; pfam07670
526224002180	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
526224002181	Nucleoside recognition; Region: Gate; pfam07670
526224002182	peptide chain release factor 2; Validated; Region: prfB; PRK00578
526224002183	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
526224002184	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
526224002185	putative active site [active]
526224002186	putative metal binding site [ion binding]; other site
526224002187	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
526224002188	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
526224002189	dimer interface [polypeptide binding]; other site
526224002190	putative anticodon binding site; other site
526224002191	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
526224002192	motif 1; other site
526224002193	active site
526224002194	motif 2; other site
526224002195	motif 3; other site
526224002196	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224002197	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224002198	peptide binding site [polypeptide binding]; other site
526224002199	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
526224002200	RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885
526224002201	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
526224002202	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
526224002203	catalytic triad [active]
526224002204	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
526224002205	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
526224002206	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224002207	ATP binding site [chemical binding]; other site
526224002208	putative Mg++ binding site [ion binding]; other site
526224002209	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224002210	nucleotide binding region [chemical binding]; other site
526224002211	ATP-binding site [chemical binding]; other site
526224002212	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
526224002213	nucleophile elbow; other site
526224002214	flagellar hook-associated protein FliD; Validated; Region: fliD; PRK06664
526224002215	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
526224002216	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
526224002217	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224002218	non-specific DNA binding site [nucleotide binding]; other site
526224002219	salt bridge; other site
526224002220	sequence-specific DNA binding site [nucleotide binding]; other site
526224002221	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
526224002222	MPN+ (JAMM) motif; other site
526224002223	Zinc-binding site [ion binding]; other site
526224002224	OstA-like protein; Region: OstA_2; pfam13100
526224002225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
526224002226	OstA-like protein; Region: OstA; cl00844
526224002227	OstA-like protein; Region: OstA; cl00844
526224002228	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
526224002229	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224002230	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
526224002231	active site
526224002232	motif I; other site
526224002233	motif II; other site
526224002234	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
526224002235	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
526224002236	dimerization interface 3.5A [polypeptide binding]; other site
526224002237	active site
526224002238	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
526224002239	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
526224002240	zinc binding site [ion binding]; other site
526224002241	putative ligand binding site [chemical binding]; other site
526224002242	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
526224002243	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
526224002244	inhibitor-cofactor binding pocket; inhibition site
526224002245	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224002246	catalytic residue [active]
526224002247	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
526224002248	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
526224002249	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
526224002250	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224002251	NAD(P) binding site [chemical binding]; other site
526224002252	active site
526224002253	Histidinol phosphatase and related phosphatases [Amino acid transport and metabolism]; Region: HisB; COG0241
526224002254	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224002255	active site
526224002256	motif I; other site
526224002257	motif II; other site
526224002258	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224002259	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002260	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
526224002261	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
526224002262	Walker A/P-loop; other site
526224002263	ATP binding site [chemical binding]; other site
526224002264	Q-loop/lid; other site
526224002265	ABC transporter signature motif; other site
526224002266	Walker B; other site
526224002267	D-loop; other site
526224002268	H-loop/switch region; other site
526224002269	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
526224002270	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
526224002271	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
526224002272	Walker A/P-loop; other site
526224002273	ATP binding site [chemical binding]; other site
526224002274	Q-loop/lid; other site
526224002275	ABC transporter signature motif; other site
526224002276	Walker B; other site
526224002277	D-loop; other site
526224002278	H-loop/switch region; other site
526224002279	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
526224002280	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
526224002281	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
526224002282	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224002283	dimer interface [polypeptide binding]; other site
526224002284	conserved gate region; other site
526224002285	putative PBP binding loops; other site
526224002286	ABC-ATPase subunit interface; other site
526224002287	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
526224002288	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224002289	dimer interface [polypeptide binding]; other site
526224002290	conserved gate region; other site
526224002291	putative PBP binding loops; other site
526224002292	ABC-ATPase subunit interface; other site
526224002293	META domain; Region: META; pfam03724
526224002294	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
526224002295	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
526224002296	active site
526224002297	metal binding site [ion binding]; metal-binding site
526224002298	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
526224002299	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
526224002300	putative binding surface; other site
526224002301	active site
526224002302	P2 response regulator binding domain; Region: P2; pfam07194
526224002303	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
526224002304	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224002305	ATP binding site [chemical binding]; other site
526224002306	Mg2+ binding site [ion binding]; other site
526224002307	G-X-G motif; other site
526224002308	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
526224002309	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
526224002310	beta-galactosidase; Region: BGL; TIGR03356
526224002311	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
526224002312	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
526224002313	Uncharacterized conserved protein [Function unknown]; Region: COG1359
526224002314	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
526224002315	putative active site [active]
526224002316	catalytic residue [active]
526224002317	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
526224002318	putative active site [active]
526224002319	catalytic residue [active]
526224002320	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
526224002321	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
526224002322	5S rRNA interface [nucleotide binding]; other site
526224002323	CTC domain interface [polypeptide binding]; other site
526224002324	L16 interface [polypeptide binding]; other site
526224002325	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
526224002326	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
526224002327	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224002328	active site
526224002329	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
526224002330	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
526224002331	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
526224002332	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
526224002333	Phosphotransferase enzyme family; Region: APH; pfam01636
526224002334	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
526224002335	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224002336	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
526224002337	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
526224002338	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
526224002339	active site
526224002340	dimer interface [polypeptide binding]; other site
526224002341	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
526224002342	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
526224002343	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
526224002344	Catalytic site [active]
526224002345	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
526224002346	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
526224002347	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
526224002348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
526224002349	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
526224002350	dimer interface [polypeptide binding]; other site
526224002351	motif 1; other site
526224002352	active site
526224002353	motif 2; other site
526224002354	motif 3; other site
526224002355	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
526224002356	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
526224002357	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224002358	catalytic residue [active]
526224002359	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
526224002360	fructuronate transporter; Provisional; Region: PRK10034; cl15264
526224002361	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224002362	sequence-specific DNA binding site [nucleotide binding]; other site
526224002363	salt bridge; other site
526224002364	Cupin domain; Region: Cupin_2; pfam07883
526224002365	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
526224002366	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
526224002367	ADP binding site [chemical binding]; other site
526224002368	magnesium binding site [ion binding]; other site
526224002369	putative shikimate binding site; other site
526224002370	Chorismate mutase type II; Region: CM_2; smart00830
526224002371	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
526224002372	Prephenate dehydratase; Region: PDT; pfam00800
526224002373	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
526224002374	putative L-Phe binding site [chemical binding]; other site
526224002375	Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, and uncharacterized proteins with a DEAD domain; Region: PLDc_Bfil_DEXD_like; cd09117
526224002376	PLD-like domain; Region: PLDc_2; pfam13091
526224002377	homodimer interface [polypeptide binding]; other site
526224002378	putative active site [active]
526224002379	catalytic site [active]
526224002380	S-adenosylmethionine synthetase; Validated; Region: PRK05250
526224002381	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
526224002382	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
526224002383	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
526224002384	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
526224002385	metal ion-dependent adhesion site (MIDAS); other site
526224002386	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
526224002387	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
526224002388	Domain of unknown function (DUF1850); Region: DUF1850; cl01950
526224002389	TRAP transporter, 4TM/12TM fusion protein; Region: TRAP_fused; TIGR02123
526224002390	DctM-like transporters; Region: DctM; pfam06808
526224002391	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
526224002392	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
526224002393	Na2 binding site [ion binding]; other site
526224002394	putative substrate binding site 1 [chemical binding]; other site
526224002395	Na binding site 1 [ion binding]; other site
526224002396	putative substrate binding site 2 [chemical binding]; other site
526224002397	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
526224002398	K+-dependent Na+/Ca+ exchanger related-protein; Region: TIGR00367
526224002399	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
526224002400	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
526224002401	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
526224002402	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
526224002403	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224002404	binding surface
526224002405	TPR motif; other site
526224002406	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224002407	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224002408	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224002409	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224002410	active site
526224002411	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
526224002412	alpha-galactosidase; Provisional; Region: PRK15076
526224002413	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
526224002414	NAD(P) binding site [chemical binding]; other site
526224002415	LDH/MDH dimer interface [polypeptide binding]; other site
526224002416	substrate binding site [chemical binding]; other site
526224002417	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
526224002418	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224002419	Zn2+ binding site [ion binding]; other site
526224002420	Mg2+ binding site [ion binding]; other site
526224002421	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
526224002422	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002423	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002424	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002425	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
526224002426	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224002427	ScpA/B protein; Region: ScpA_ScpB; cl00598
526224002428	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
526224002429	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
526224002430	Septation ring formation regulator, EzrA; Region: EzrA; pfam06160
526224002431	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
526224002432	putative oxidoreductase; Provisional; Region: PRK12831
526224002433	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
526224002434	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224002435	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224002436	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
526224002437	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
526224002438	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
526224002439	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
526224002440	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3330
526224002441	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
526224002442	ABC1 family; Region: ABC1; pfam03109
526224002443	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
526224002444	active site
526224002445	ATP binding site [chemical binding]; other site
526224002446	Uncharacterized conserved protein [Function unknown]; Region: COG3937
526224002447	TM2 domain; Region: TM2; pfam05154
526224002448	DNA methylase; Region: N6_N4_Mtase; cl17433
526224002449	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224002450	S-adenosylmethionine binding site [chemical binding]; other site
526224002451	DNA methylase; Region: N6_N4_Mtase; cl17433
526224002452	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002453	binding surface
526224002454	TPR motif; other site
526224002455	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224002456	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002457	TPR motif; other site
526224002458	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002459	binding surface
526224002460	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224002461	binding surface
526224002462	TPR motif; other site
526224002463	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
526224002464	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
526224002465	gamma subunit interface [polypeptide binding]; other site
526224002466	epsilon subunit interface [polypeptide binding]; other site
526224002467	LBP interface [polypeptide binding]; other site
526224002468	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
526224002469	active site
526224002470	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
526224002471	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
526224002472	active site
526224002473	(T/H)XGH motif; other site
526224002474	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
526224002475	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
526224002476	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224002477	FeS/SAM binding site; other site
526224002478	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
526224002479	FecR protein; Region: FecR; pfam04773
526224002480	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
526224002481	Protein of unknown function (DUF464); Region: DUF464; cl01080
526224002482	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
526224002483	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
526224002484	Selenophosphate synthase [Amino acid transport and metabolism]; Region: SelD; COG0709
526224002485	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
526224002486	dimerization interface [polypeptide binding]; other site
526224002487	putative ATP binding site [chemical binding]; other site
526224002488	Predicted periplasmic protein (DUF2271); Region: DUF2271; cl17856
526224002489	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
526224002490	putative FMN binding site [chemical binding]; other site
526224002491	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
526224002492	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
526224002493	carbamoyl-phosphate synthase, large subunit; Region: CPSaseII_lrg; TIGR01369
526224002494	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
526224002495	Na2 binding site [ion binding]; other site
526224002496	putative substrate binding site 1 [chemical binding]; other site
526224002497	Na binding site 1 [ion binding]; other site
526224002498	putative substrate binding site 2 [chemical binding]; other site
526224002499	pyruvate phosphate dikinase; Provisional; Region: PRK09279
526224002500	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
526224002501	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
526224002502	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
526224002503	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
526224002504	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
526224002505	EamA-like transporter family; Region: EamA; pfam00892
526224002506	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
526224002507	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
526224002508	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
526224002509	nucleotide binding region [chemical binding]; other site
526224002510	SEC-C motif; Region: SEC-C; pfam02810
526224002511	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
526224002512	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
526224002513	Clp amino terminal domain; Region: Clp_N; pfam02861
526224002514	Clp amino terminal domain; Region: Clp_N; pfam02861
526224002515	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224002516	Walker A motif; other site
526224002517	ATP binding site [chemical binding]; other site
526224002518	Walker B motif; other site
526224002519	arginine finger; other site
526224002520	UvrB/uvrC motif; Region: UVR; pfam02151
526224002521	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224002522	Walker A motif; other site
526224002523	ATP binding site [chemical binding]; other site
526224002524	Walker B motif; other site
526224002525	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
526224002526	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
526224002527	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224002528	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224002529	DNA binding residues [nucleotide binding]
526224002530	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224002531	Walker A motif; other site
526224002532	ATP binding site [chemical binding]; other site
526224002533	Walker B motif; other site
526224002534	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
526224002535	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
526224002536	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
526224002537	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224002538	FeS/SAM binding site; other site
526224002539	Helix-turn-helix domain; Region: HTH_25; pfam13413
526224002540	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
526224002541	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
526224002542	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
526224002543	Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors; Region: STAS; cl00604
526224002544	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224002545	active site residue [active]
526224002546	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
526224002547	EamA-like transporter family; Region: EamA; pfam00892
526224002548	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
526224002549	endonuclease III; Region: ENDO3c; smart00478
526224002550	minor groove reading motif; other site
526224002551	helix-hairpin-helix signature motif; other site
526224002552	substrate binding pocket [chemical binding]; other site
526224002553	active site
526224002554	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
526224002555	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
526224002556	triosephosphate isomerase; Provisional; Region: PRK14565
526224002557	substrate binding site [chemical binding]; other site
526224002558	dimer interface [polypeptide binding]; other site
526224002559	catalytic triad [active]
526224002560	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
526224002561	Isochorismatase family; Region: Isochorismatase; pfam00857
526224002562	catalytic triad [active]
526224002563	dimer interface [polypeptide binding]; other site
526224002564	conserved cis-peptide bond; other site
526224002565	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
526224002566	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
526224002567	Serine dehydrogenase proteinase; Region: SDH_sah; pfam01972
526224002568	active site
526224002569	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
526224002570	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
526224002571	putative active site [active]
526224002572	cell division protein FtsA; Region: ftsA; TIGR01174
526224002573	Cell division protein FtsA; Region: FtsA; smart00842
526224002574	Cell division protein FtsA; Region: FtsA; pfam14450
526224002575	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224002576	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224002577	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
526224002578	Domain of unknown function (DUF368); Region: DUF368; pfam04018
526224002579	PBP superfamily domain; Region: PBP_like_2; cl17296
526224002580	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
526224002581	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224002582	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
526224002583	homotrimer interaction site [polypeptide binding]; other site
526224002584	zinc binding site [ion binding]; other site
526224002585	CDP-binding sites; other site
526224002586	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
526224002587	substrate binding pocket [chemical binding]; other site
526224002588	substrate-Mg2+ binding site; other site
526224002589	aspartate-rich region 1; other site
526224002590	aspartate-rich region 2; other site
526224002591	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002592	TPR motif; other site
526224002593	binding surface
526224002594	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
526224002595	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224002596	S-adenosylmethionine binding site [chemical binding]; other site
526224002597	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
526224002598	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002599	TPR motif; other site
526224002600	binding surface
526224002601	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224002602	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224002603	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002604	binding surface
526224002605	TPR motif; other site
526224002606	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
526224002607	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
526224002608	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
526224002609	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224002610	dimerization interface [polypeptide binding]; other site
526224002611	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224002612	dimer interface [polypeptide binding]; other site
526224002613	putative CheW interface [polypeptide binding]; other site
526224002614	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
526224002615	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
526224002616	dimer interface [polypeptide binding]; other site
526224002617	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
526224002618	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
526224002619	GAF domain; Region: GAF_3; pfam13492
526224002620	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
526224002621	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
526224002622	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
526224002623	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
526224002624	dimer interface [polypeptide binding]; other site
526224002625	phosphorylation site [posttranslational modification]
526224002626	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224002627	ATP binding site [chemical binding]; other site
526224002628	Mg2+ binding site [ion binding]; other site
526224002629	G-X-G motif; other site
526224002630	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
526224002631	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
526224002632	active site
526224002633	catalytic site [active]
526224002634	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
526224002635	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224002636	active site
526224002637	phosphorylation site [posttranslational modification]
526224002638	intermolecular recognition site; other site
526224002639	dimerization interface [polypeptide binding]; other site
526224002640	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
526224002641	dimer interface [polypeptide binding]; other site
526224002642	substrate binding site [chemical binding]; other site
526224002643	ATP binding site [chemical binding]; other site
526224002644	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
526224002645	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
526224002646	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
526224002647	Methyltransferase domain; Region: Methyltransf_26; pfam13659
526224002648	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
526224002649	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
526224002650	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
526224002651	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
526224002652	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
526224002653	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224002654	dimer interface [polypeptide binding]; other site
526224002655	conserved gate region; other site
526224002656	putative PBP binding loops; other site
526224002657	ABC-ATPase subunit interface; other site
526224002658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224002659	dimer interface [polypeptide binding]; other site
526224002660	conserved gate region; other site
526224002661	putative PBP binding loops; other site
526224002662	ABC-ATPase subunit interface; other site
526224002663	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
526224002664	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
526224002665	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
526224002666	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224002667	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224002668	substrate binding pocket [chemical binding]; other site
526224002669	membrane-bound complex binding site; other site
526224002670	hinge residues; other site
526224002671	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
526224002672	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
526224002673	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224002674	active site
526224002675	phosphorylation site [posttranslational modification]
526224002676	intermolecular recognition site; other site
526224002677	dimerization interface [polypeptide binding]; other site
526224002678	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
526224002679	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; cl00512
526224002680	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
526224002681	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
526224002682	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224002683	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224002684	DNA binding residues [nucleotide binding]
526224002685	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
526224002686	HemN C-terminal domain; Region: HemN_C; pfam06969
526224002687	Trp repressor protein; Region: Trp_repressor; cl17266
526224002688	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224002689	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002690	DNA polymerase III subunit beta; Validated; Region: PRK05643
526224002691	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
526224002692	putative DNA binding surface [nucleotide binding]; other site
526224002693	dimer interface [polypeptide binding]; other site
526224002694	beta-clamp/clamp loader binding surface; other site
526224002695	beta-clamp/translesion DNA polymerase binding surface; other site
526224002696	recombination protein F; Reviewed; Region: recF; PRK00064
526224002697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224002698	Walker A/P-loop; other site
526224002699	ATP binding site [chemical binding]; other site
526224002700	Q-loop/lid; other site
526224002701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224002702	ABC transporter signature motif; other site
526224002703	Walker B; other site
526224002704	D-loop; other site
526224002705	H-loop/switch region; other site
526224002706	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002707	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002708	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002709	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002710	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002711	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002712	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002713	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
526224002714	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224002715	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002716	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002717	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002718	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002719	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224002720	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
526224002721	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
526224002722	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
526224002723	putative homodimer interface [polypeptide binding]; other site
526224002724	putative active site pocket [active]
526224002725	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
526224002726	Protein of unknown function (DUF554); Region: DUF554; pfam04474
526224002727	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224002728	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224002729	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002730	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002731	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224002732	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002733	TspO/MBR family; Region: TspO_MBR; pfam03073
526224002734	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
526224002735	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
526224002736	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
526224002737	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
526224002738	MarR family; Region: MarR_2; pfam12802
526224002739	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
526224002740	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
526224002741	B12 binding site [chemical binding]; other site
526224002742	SurA N-terminal domain; Region: SurA_N; pfam09312
526224002743	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
526224002744	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224002745	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
526224002746	TM-ABC transporter signature motif; other site
526224002747	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224002748	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
526224002749	TM-ABC transporter signature motif; other site
526224002750	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224002751	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224002752	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
526224002753	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
526224002754	Walker A/P-loop; other site
526224002755	ATP binding site [chemical binding]; other site
526224002756	Q-loop/lid; other site
526224002757	ABC transporter signature motif; other site
526224002758	Walker B; other site
526224002759	D-loop; other site
526224002760	H-loop/switch region; other site
526224002761	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
526224002762	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
526224002763	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
526224002764	ligand binding site [chemical binding]; other site
526224002765	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
526224002766	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
526224002767	ligand binding site [chemical binding]; other site
526224002768	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
526224002769	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
526224002770	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
526224002771	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
526224002772	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
526224002773	intersubunit interface [polypeptide binding]; other site
526224002774	active site
526224002775	catalytic residue [active]
526224002776	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
526224002777	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
526224002778	inhibitor-cofactor binding pocket; inhibition site
526224002779	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224002780	catalytic residue [active]
526224002781	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
526224002782	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
526224002783	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224002784	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224002785	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
526224002786	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
526224002787	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
526224002788	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
526224002789	23S rRNA interface [nucleotide binding]; other site
526224002790	L3 interface [polypeptide binding]; other site
526224002791	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
526224002792	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
526224002793	primosome assembly protein PriA; Validated; Region: PRK05580
526224002794	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224002795	ATP binding site [chemical binding]; other site
526224002796	putative Mg++ binding site [ion binding]; other site
526224002797	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224002798	ATP-binding site [chemical binding]; other site
526224002799	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
526224002800	DNA binding residues [nucleotide binding]
526224002801	Response regulator receiver domain; Region: Response_reg; pfam00072
526224002802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224002803	active site
526224002804	phosphorylation site [posttranslational modification]
526224002805	intermolecular recognition site; other site
526224002806	dimerization interface [polypeptide binding]; other site
526224002807	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
526224002808	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
526224002809	Substrate binding site; other site
526224002810	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
526224002811	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14611
526224002812	YcfA-like protein; Region: YcfA; cl00752
526224002813	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
526224002814	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224002815	Uncharacterized conserved protein [Function unknown]; Region: COG1479
526224002816	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224002817	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
526224002818	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
526224002819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224002820	active site
526224002821	phosphorylation site [posttranslational modification]
526224002822	intermolecular recognition site; other site
526224002823	dimerization interface [polypeptide binding]; other site
526224002824	CheB methylesterase; Region: CheB_methylest; pfam01339
526224002825	Apolipoprotein N-acyltransferase [Cell envelope biogenesis, outer membrane]; Region: Lnt; COG0815
526224002826	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
526224002827	putative active site [active]
526224002828	catalytic triad [active]
526224002829	putative dimer interface [polypeptide binding]; other site
526224002830	Hemerythrin; Region: Hemerythrin; cd12107
526224002831	Fe binding site [ion binding]; other site
526224002832	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
526224002833	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224002834	Walker A motif; other site
526224002835	ATP binding site [chemical binding]; other site
526224002836	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
526224002837	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
526224002838	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
526224002839	active site
526224002840	HslU subunit interaction site [polypeptide binding]; other site
526224002841	ABC-2 type transporter; Region: ABC2_membrane; cl17235
526224002842	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
526224002843	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
526224002844	Walker A/P-loop; other site
526224002845	ATP binding site [chemical binding]; other site
526224002846	Q-loop/lid; other site
526224002847	ABC transporter signature motif; other site
526224002848	Walker B; other site
526224002849	D-loop; other site
526224002850	H-loop/switch region; other site
526224002851	CAAX protease self-immunity; Region: Abi; pfam02517
526224002852	YcaO-like family; Region: YcaO; pfam02624
526224002853	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
526224002854	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
526224002855	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
526224002856	NADPH bind site [chemical binding]; other site
526224002857	putative FMN binding site [chemical binding]; other site
526224002858	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
526224002859	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
526224002860	active site
526224002861	metal binding site [ion binding]; metal-binding site
526224002862	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
526224002863	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224002864	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224002865	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
526224002866	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
526224002867	homodimer interface [polypeptide binding]; other site
526224002868	metal binding site [ion binding]; metal-binding site
526224002869	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
526224002870	homodimer interface [polypeptide binding]; other site
526224002871	active site
526224002872	putative chemical substrate binding site [chemical binding]; other site
526224002873	metal binding site [ion binding]; metal-binding site
526224002874	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
526224002875	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
526224002876	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
526224002877	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224002878	RNA binding surface [nucleotide binding]; other site
526224002879	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
526224002880	active site
526224002881	Cache domain; Region: Cache_1; pfam02743
526224002882	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224002883	dimer interface [polypeptide binding]; other site
526224002884	putative CheW interface [polypeptide binding]; other site
526224002885	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
526224002886	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
526224002887	RNB domain; Region: RNB; pfam00773
526224002888	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
526224002889	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
526224002890	RNA binding site [nucleotide binding]; other site
526224002891	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
526224002892	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
526224002893	Tetramer interface [polypeptide binding]; other site
526224002894	active site
526224002895	FMN-binding site [chemical binding]; other site
526224002896	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
526224002897	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
526224002898	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224002899	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224002900	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002901	TPR motif; other site
526224002902	TPR repeat; Region: TPR_11; pfam13414
526224002903	binding surface
526224002904	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224002905	TPR motif; other site
526224002906	binding surface
526224002907	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
526224002908	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
526224002909	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
526224002910	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
526224002911	Flagellar protein (FlbD); Region: FlbD; pfam06289
526224002912	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
526224002913	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
526224002914	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
526224002915	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224002916	ligand binding site [chemical binding]; other site
526224002917	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
526224002918	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224002919	S-adenosylmethionine binding site [chemical binding]; other site
526224002920	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
526224002921	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
526224002922	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
526224002923	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
526224002924	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
526224002925	dimerization domain swap beta strand [polypeptide binding]; other site
526224002926	regulatory protein interface [polypeptide binding]; other site
526224002927	active site
526224002928	regulatory phosphorylation site [posttranslational modification]; other site
526224002929	Type III pantothenate kinase; Region: Pan_kinase; pfam03309
526224002930	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
526224002931	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
526224002932	active site
526224002933	NTP binding site [chemical binding]; other site
526224002934	metal binding triad [ion binding]; metal-binding site
526224002935	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
526224002936	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
526224002937	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224002938	Protein export membrane protein; Region: SecD_SecF; cl14618
526224002939	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
526224002940	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
526224002941	dimer interface [polypeptide binding]; other site
526224002942	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
526224002943	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224002944	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224002945	DNA binding residues [nucleotide binding]
526224002946	Putative zinc-finger; Region: zf-HC2; pfam13490
526224002947	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
526224002948	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
526224002949	active site
526224002950	substrate binding site [chemical binding]; other site
526224002951	cosubstrate binding site; other site
526224002952	catalytic site [active]
526224002953	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
526224002954	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
526224002955	dimerization interface [polypeptide binding]; other site
526224002956	putative ATP binding site [chemical binding]; other site
526224002957	translation initiation factor IF-2; Region: IF-2; TIGR00487
526224002958	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
526224002959	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
526224002960	G1 box; other site
526224002961	putative GEF interaction site [polypeptide binding]; other site
526224002962	GTP/Mg2+ binding site [chemical binding]; other site
526224002963	Switch I region; other site
526224002964	G2 box; other site
526224002965	G3 box; other site
526224002966	Switch II region; other site
526224002967	G4 box; other site
526224002968	G5 box; other site
526224002969	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
526224002970	Translation-initiation factor 2; Region: IF-2; pfam11987
526224002971	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
526224002972	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
526224002973	flagellin; Provisional; Region: PRK12804
526224002974	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
526224002975	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
526224002976	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
526224002977	Peptidase family M28; Region: Peptidase_M28; pfam04389
526224002978	metal binding site [ion binding]; metal-binding site
526224002979	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
526224002980	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
526224002981	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224002982	active site residue [active]
526224002983	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
526224002984	Peptidase family M50; Region: Peptidase_M50; pfam02163
526224002985	active site
526224002986	putative substrate binding region [chemical binding]; other site
526224002987	ornithine carbamoyltransferase; Provisional; Region: PRK00779
526224002988	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
526224002989	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
526224002990	argininosuccinate synthase; Provisional; Region: PRK13820
526224002991	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
526224002992	ANP binding site [chemical binding]; other site
526224002993	Substrate Binding Site II [chemical binding]; other site
526224002994	Substrate Binding Site I [chemical binding]; other site
526224002995	argininosuccinate lyase; Provisional; Region: PRK00855
526224002996	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
526224002997	active sites [active]
526224002998	tetramer interface [polypeptide binding]; other site
526224002999	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224003000	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224003001	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
526224003002	putative transporter; Provisional; Region: PRK10484
526224003003	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
526224003004	Na binding site [ion binding]; other site
526224003005	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224003006	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
526224003007	Bax inhibitor 1 like; Region: BaxI_1; cl17691
526224003008	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224003009	ligand binding site [chemical binding]; other site
526224003010	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
526224003011	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
526224003012	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
526224003013	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
526224003014	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
526224003015	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
526224003016	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003017	binding surface
526224003018	TPR motif; other site
526224003019	TPR repeat; Region: TPR_11; pfam13414
526224003020	rod shape-determining protein MreB; Provisional; Region: PRK13927
526224003021	MreB and similar proteins; Region: MreB_like; cd10225
526224003022	nucleotide binding site [chemical binding]; other site
526224003023	Mg binding site [ion binding]; other site
526224003024	putative protofilament interaction site [polypeptide binding]; other site
526224003025	RodZ interaction site [polypeptide binding]; other site
526224003026	rod shape-determining protein MreC; Provisional; Region: PRK13922
526224003027	rod shape-determining protein MreC; Region: MreC; pfam04085
526224003028	rod shape-determining protein MreD; Region: MreD; cl01087
526224003029	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
526224003030	putative active site [active]
526224003031	putative metal binding residues [ion binding]; other site
526224003032	signature motif; other site
526224003033	putative triphosphate binding site [ion binding]; other site
526224003034	dimer interface [polypeptide binding]; other site
526224003035	Domain of unknown function (DUF4390); Region: DUF4390; pfam14334
526224003036	NlpC/P60 family; Region: NLPC_P60; cl17555
526224003037	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
526224003038	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003039	Walker A motif; other site
526224003040	ATP binding site [chemical binding]; other site
526224003041	Walker B motif; other site
526224003042	arginine finger; other site
526224003043	Peptidase family M41; Region: Peptidase_M41; pfam01434
526224003044	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
526224003045	putative active site pocket [active]
526224003046	DmpA/OAT superfamily; composed of L-aminopeptidase D-amidase/D-esterase (DmpA), ornithine acetyltransferase (OAT) and similar proteins. DmpA is an aminopeptidase that releases N-terminal D and L amino acids from peptide substrates. This group represents...; Region: DmpA_OAT; cl00603
526224003047	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
526224003048	Na binding site [ion binding]; other site
526224003049	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
526224003050	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
526224003051	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
526224003052	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
526224003053	Divergent AAA domain; Region: AAA_4; pfam04326
526224003054	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
526224003055	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224003056	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224003057	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
526224003058	Phosphagen (guanidino) kinases; Region: phosphagen_kinases; cl02823
526224003059	ADP binding site [chemical binding]; other site
526224003060	phosphagen binding site; other site
526224003061	substrate specificity loop; other site
526224003062	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
526224003063	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
526224003064	substrate binding site; other site
526224003065	dimer interface; other site
526224003066	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224003067	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
526224003068	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
526224003069	Transglycosylase; Region: Transgly; pfam00912
526224003070	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
526224003071	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
526224003072	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
526224003073	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
526224003074	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224003075	dimer interface [polypeptide binding]; other site
526224003076	conserved gate region; other site
526224003077	putative PBP binding loops; other site
526224003078	ABC-ATPase subunit interface; other site
526224003079	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
526224003080	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224003081	dimer interface [polypeptide binding]; other site
526224003082	conserved gate region; other site
526224003083	putative PBP binding loops; other site
526224003084	ABC-ATPase subunit interface; other site
526224003085	signal recognition particle protein; Provisional; Region: PRK10867
526224003086	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
526224003087	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
526224003088	Signal peptide binding domain; Region: SRP_SPB; pfam02978
526224003089	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
526224003090	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
526224003091	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
526224003092	RimM protein, required for 16S rRNA processing [Translation, ribosomal structure and biogenesis]; Region: RimM; COG0806
526224003093	RimM N-terminal domain; Region: RimM; pfam01782
526224003094	PRC-barrel domain; Region: PRC; pfam05239
526224003095	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
526224003096	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224003097	active site
526224003098	nucleotide binding site [chemical binding]; other site
526224003099	HIGH motif; other site
526224003100	KMSKS motif; other site
526224003101	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
526224003102	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
526224003103	Domain of unknown function (DUF305); Region: DUF305; pfam03713
526224003104	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
526224003105	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
526224003106	putative NAD(P) binding site [chemical binding]; other site
526224003107	putative substrate binding site [chemical binding]; other site
526224003108	catalytic Zn binding site [ion binding]; other site
526224003109	structural Zn binding site [ion binding]; other site
526224003110	dimer interface [polypeptide binding]; other site
526224003111	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
526224003112	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
526224003113	putative dimer interface [polypeptide binding]; other site
526224003114	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
526224003115	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
526224003116	putative dimer interface [polypeptide binding]; other site
526224003117	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
526224003118	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
526224003119	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003120	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224003121	Walker A motif; other site
526224003122	ATP binding site [chemical binding]; other site
526224003123	Walker B motif; other site
526224003124	arginine finger; other site
526224003125	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
526224003126	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
526224003127	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
526224003128	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
526224003129	active site
526224003130	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
526224003131	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
526224003132	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
526224003133	dimer interface [polypeptide binding]; other site
526224003134	active site
526224003135	metal binding site [ion binding]; metal-binding site
526224003136	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
526224003137	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
526224003138	G-X-X-G motif; other site
526224003139	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
526224003140	RxxxH motif; other site
526224003141	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
526224003142	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
526224003143	Haemolytic domain; Region: Haemolytic; pfam01809
526224003144	Ribosomal protein L34; Region: Ribosomal_L34; pfam00468
526224003145	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
526224003146	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
526224003147	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
526224003148	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
526224003149	dimer interface [polypeptide binding]; other site
526224003150	ADP-ribose binding site [chemical binding]; other site
526224003151	active site
526224003152	nudix motif; other site
526224003153	metal binding site [ion binding]; metal-binding site
526224003154	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
526224003155	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
526224003156	dimer interface [polypeptide binding]; other site
526224003157	phosphorylation site [posttranslational modification]
526224003158	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224003159	ATP binding site [chemical binding]; other site
526224003160	Mg2+ binding site [ion binding]; other site
526224003161	G-X-G motif; other site
526224003162	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003163	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224003164	HEAT repeats; Region: HEAT_2; pfam13646
526224003165	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
526224003166	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
526224003167	motif 1; other site
526224003168	active site
526224003169	motif 2; other site
526224003170	motif 3; other site
526224003171	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
526224003172	DHHA1 domain; Region: DHHA1; pfam02272
526224003173	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
526224003174	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
526224003175	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
526224003176	protein binding site [polypeptide binding]; other site
526224003177	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
526224003178	protein binding site [polypeptide binding]; other site
526224003179	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
526224003180	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
526224003181	putative acyl-acceptor binding pocket; other site
526224003182	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
526224003183	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224003184	NAD(P) binding site [chemical binding]; other site
526224003185	active site
526224003186	multifunctional aminopeptidase A; Provisional; Region: PRK00913
526224003187	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
526224003188	interface (dimer of trimers) [polypeptide binding]; other site
526224003189	Substrate-binding/catalytic site; other site
526224003190	Zn-binding sites [ion binding]; other site
526224003191	maltose O-acetyltransferase; Provisional; Region: PRK10092
526224003192	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
526224003193	active site
526224003194	substrate binding site [chemical binding]; other site
526224003195	trimer interface [polypeptide binding]; other site
526224003196	CoA binding site [chemical binding]; other site
526224003197	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
526224003198	putative dimer interface [polypeptide binding]; other site
526224003199	[2Fe-2S] cluster binding site [ion binding]; other site
526224003200	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
526224003201	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
526224003202	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
526224003203	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
526224003204	catalytic loop [active]
526224003205	iron binding site [ion binding]; other site
526224003206	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
526224003207	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003208	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224003209	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
526224003210	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
526224003211	putative active site [active]
526224003212	oxyanion strand; other site
526224003213	catalytic triad [active]
526224003214	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
526224003215	putative active site pocket [active]
526224003216	4-fold oligomerization interface [polypeptide binding]; other site
526224003217	metal binding residues [ion binding]; metal-binding site
526224003218	3-fold/trimer interface [polypeptide binding]; other site
526224003219	glycerate kinase; Region: TIGR00045
526224003220	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
526224003221	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
526224003222	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
526224003223	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
526224003224	fructuronate transporter; Provisional; Region: PRK10034; cl15264
526224003225	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
526224003226	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
526224003227	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
526224003228	metal binding site [ion binding]; metal-binding site
526224003229	dimer interface [polypeptide binding]; other site
526224003230	TPR repeat; Region: TPR_11; pfam13414
526224003231	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003232	binding surface
526224003233	TPR motif; other site
526224003234	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003235	TPR motif; other site
526224003236	binding surface
526224003237	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224003238	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
526224003239	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
526224003240	GatB domain; Region: GatB_Yqey; smart00845
526224003241	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
526224003242	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224003243	active site
526224003244	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
526224003245	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
526224003246	Ligand binding site; other site
526224003247	Putative Catalytic site; other site
526224003248	DXD motif; other site
526224003249	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
526224003250	extended (e) SDRs; Region: SDR_e; cd08946
526224003251	NAD(P) binding site [chemical binding]; other site
526224003252	substrate binding site [chemical binding]; other site
526224003253	active site
526224003254	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
526224003255	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
526224003256	extended (e) SDRs; Region: SDR_e; cd08946
526224003257	NAD(P) binding site [chemical binding]; other site
526224003258	substrate binding site [chemical binding]; other site
526224003259	active site
526224003260	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
526224003261	Phage terminase large subunit; Region: Terminase_3; cl12054
526224003262	intracellular protease, PfpI family; Region: PfpI; TIGR01382
526224003263	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
526224003264	proposed catalytic triad [active]
526224003265	conserved cys residue [active]
526224003266	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
526224003267	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
526224003268	DNA binding residues [nucleotide binding]
526224003269	Chromate transporter; Region: Chromate_transp; pfam02417
526224003270	Chromate transporter; Region: Chromate_transp; pfam02417
526224003271	RecX family; Region: RecX; cl00936
526224003272	YcxB-like protein; Region: YcxB; pfam14317
526224003273	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
526224003274	active site
526224003275	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
526224003276	Predicted membrane protein [Function unknown]; Region: COG2510
526224003277	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
526224003278	diiron binding motif [ion binding]; other site
526224003279	CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431
526224003280	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
526224003281	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224003282	motif II; other site
526224003283	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
526224003284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003285	Walker A motif; other site
526224003286	ATP binding site [chemical binding]; other site
526224003287	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
526224003288	Walker B motif; other site
526224003289	arginine finger; other site
526224003290	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
526224003291	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
526224003292	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003293	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224003294	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
526224003295	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
526224003296	Cell division protein ZapA; Region: ZapA; pfam05164
526224003297	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224003298	dimerization interface [polypeptide binding]; other site
526224003299	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003300	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003301	dimer interface [polypeptide binding]; other site
526224003302	putative CheW interface [polypeptide binding]; other site
526224003303	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
526224003304	homopentamer interface [polypeptide binding]; other site
526224003305	active site
526224003306	Rubrerythrin [Energy production and conversion]; Region: COG1592
526224003307	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
526224003308	binuclear metal center [ion binding]; other site
526224003309	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
526224003310	iron binding site [ion binding]; other site
526224003311	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
526224003312	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
526224003313	dimer interface [polypeptide binding]; other site
526224003314	active site residues [active]
526224003315	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
526224003316	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; cl09920
526224003317	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
526224003318	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
526224003319	dimer interface [polypeptide binding]; other site
526224003320	active site
526224003321	CoA binding pocket [chemical binding]; other site
526224003322	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
526224003323	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
526224003324	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224003325	RNA binding surface [nucleotide binding]; other site
526224003326	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
526224003327	active site
526224003328	Leucine rich repeat; Region: LRR_8; pfam13855
526224003329	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
526224003330	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224003331	RNA binding surface [nucleotide binding]; other site
526224003332	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
526224003333	active site
526224003334	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
526224003335	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224003336	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
526224003337	putative ribose interaction site [chemical binding]; other site
526224003338	putative ADP binding site [chemical binding]; other site
526224003339	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
526224003340	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224003341	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224003342	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
526224003343	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
526224003344	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224003345	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
526224003346	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003347	Walker A motif; other site
526224003348	ATP binding site [chemical binding]; other site
526224003349	Walker B motif; other site
526224003350	arginine finger; other site
526224003351	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
526224003352	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224003353	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224003354	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
526224003355	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
526224003356	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
526224003357	acyl-activating enzyme (AAE) consensus motif; other site
526224003358	acyl-activating enzyme (AAE) consensus motif; other site
526224003359	AMP binding site [chemical binding]; other site
526224003360	active site
526224003361	CoA binding site [chemical binding]; other site
526224003362	Haemolysin-III related; Region: HlyIII; cl03831
526224003363	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
526224003364	EamA-like transporter family; Region: EamA; cl17759
526224003365	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
526224003366	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
526224003367	ATP-grasp domain; Region: ATP-grasp_4; cl17255
526224003368	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
526224003369	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
526224003370	putative active site [active]
526224003371	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
526224003372	hypothetical protein; Reviewed; Region: PRK12497
526224003373	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
526224003374	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224003375	Zn2+ binding site [ion binding]; other site
526224003376	Mg2+ binding site [ion binding]; other site
526224003377	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
526224003378	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
526224003379	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
526224003380	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
526224003381	active site
526224003382	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
526224003383	Uncharacterized conserved protein [Function unknown]; Region: COG2128
526224003384	Uncharacterized ACR, YggU family COG1872; Region: DUF167; cl00811
526224003385	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
526224003386	EamA-like transporter family; Region: EamA; pfam00892
526224003387	MoxR-like ATPases [General function prediction only]; Region: COG0714
526224003388	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
526224003389	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224003390	4Fe-4S binding domain; Region: Fer4; cl02805
526224003391	formamidopyrimidine-DNA glycosylase; Provisional; Region: PRK14811
526224003392	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
526224003393	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
526224003394	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
526224003395	NAD binding site [chemical binding]; other site
526224003396	putative substrate binding site 2 [chemical binding]; other site
526224003397	putative substrate binding site 1 [chemical binding]; other site
526224003398	active site
526224003399	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
526224003400	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cd09754
526224003401	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cl09909
526224003402	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
526224003403	CRISPR-associated autoregulator DevR family; Region: cas_MJ0381; TIGR01875
526224003404	CRISPR-associated protein Cas5, subtype I-B/TNEAP; Region: cas_Cas5t; TIGR01895
526224003405	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
526224003406	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
526224003407	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
526224003408	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
526224003409	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
526224003410	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
526224003411	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
526224003412	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224003413	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224003414	ligand binding site [chemical binding]; other site
526224003415	flexible hinge region; other site
526224003416	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224003417	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224003418	ligand binding site [chemical binding]; other site
526224003419	flexible hinge region; other site
526224003420	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224003421	ligand binding site [chemical binding]; other site
526224003422	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224003423	ligand binding site [chemical binding]; other site
526224003424	flexible hinge region; other site
526224003425	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
526224003426	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224003427	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003428	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224003429	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
526224003430	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
526224003431	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
526224003432	putative substrate translocation pore; other site
526224003433	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
526224003434	putative substrate translocation pore; other site
526224003435	Cache domain; Region: Cache_1; pfam02743
526224003436	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003437	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003438	dimer interface [polypeptide binding]; other site
526224003439	putative CheW interface [polypeptide binding]; other site
526224003440	Uncharacterized protein with conserved CXXC pairs [Function unknown]; Region: COG3862
526224003441	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
526224003442	active site
526224003443	Mn binding site [ion binding]; other site
526224003444	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
526224003445	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224003446	Predicted dehydrogenase [General function prediction only]; Region: COG0579
526224003447	hydroxyglutarate oxidase; Provisional; Region: PRK11728
526224003448	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
526224003449	glycerol kinase; Provisional; Region: glpK; PRK00047
526224003450	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
526224003451	N- and C-terminal domain interface [polypeptide binding]; other site
526224003452	active site
526224003453	MgATP binding site [chemical binding]; other site
526224003454	catalytic site [active]
526224003455	metal binding site [ion binding]; metal-binding site
526224003456	glycerol binding site [chemical binding]; other site
526224003457	homotetramer interface [polypeptide binding]; other site
526224003458	homodimer interface [polypeptide binding]; other site
526224003459	FBP binding site [chemical binding]; other site
526224003460	protein IIAGlc interface [polypeptide binding]; other site
526224003461	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
526224003462	amphipathic channel; other site
526224003463	Asn-Pro-Ala signature motifs; other site
526224003464	Rubrerythrin [Energy production and conversion]; Region: COG1592
526224003465	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
526224003466	binuclear metal center [ion binding]; other site
526224003467	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
526224003468	iron binding site [ion binding]; other site
526224003469	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
526224003470	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
526224003471	putative substrate translocation pore; other site
526224003472	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
526224003473	active site
526224003474	catalytic triad [active]
526224003475	oxyanion hole [active]
526224003476	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
526224003477	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
526224003478	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
526224003479	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
526224003480	active site
526224003481	HIGH motif; other site
526224003482	KMSKS motif; other site
526224003483	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
526224003484	tRNA binding surface [nucleotide binding]; other site
526224003485	anticodon binding site; other site
526224003486	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
526224003487	dimer interface [polypeptide binding]; other site
526224003488	putative tRNA-binding site [nucleotide binding]; other site
526224003489	Cache domain; Region: Cache_1; pfam02743
526224003490	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224003491	dimerization interface [polypeptide binding]; other site
526224003492	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003493	dimer interface [polypeptide binding]; other site
526224003494	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
526224003495	putative CheW interface [polypeptide binding]; other site
526224003496	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
526224003497	Methanothermobacter thermautotrophicus Mth212-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Mth212-like_AP-endo; cd09085
526224003498	active site
526224003499	putative catalytic site [active]
526224003500	phosphate binding site A [ion binding]; other site
526224003501	DNA binding site [nucleotide binding]
526224003502	metal binding site A [ion binding]; metal-binding site
526224003503	putative AP binding site [nucleotide binding]; other site
526224003504	putative metal binding site B [ion binding]; other site
526224003505	phosphate binding site B [ion binding]; other site
526224003506	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
526224003507	anti sigma factor interaction site; other site
526224003508	regulatory phosphorylation site [posttranslational modification]; other site
526224003509	YGGT family; Region: YGGT; cl00508
526224003510	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003511	binding surface
526224003512	TPR motif; other site
526224003513	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
526224003514	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
526224003515	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
526224003516	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
526224003517	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
526224003518	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
526224003519	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
526224003520	active site
526224003521	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
526224003522	MgtC family; Region: MgtC; pfam02308
526224003523	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
526224003524	active pocket/dimerization site; other site
526224003525	active site
526224003526	phosphorylation site [posttranslational modification]
526224003527	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
526224003528	active site
526224003529	catalytic residues [active]
526224003530	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
526224003531	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224003532	ligand binding site [chemical binding]; other site
526224003533	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
526224003534	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224003535	ligand binding site [chemical binding]; other site
526224003536	Restriction alleviation protein Lar; Region: Lar_restr_allev; pfam14354
526224003537	Methyltransferase domain; Region: Methyltransf_23; pfam13489
526224003538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224003539	S-adenosylmethionine binding site [chemical binding]; other site
526224003540	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224003541	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224003542	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
526224003543	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
526224003544	GDP-binding site [chemical binding]; other site
526224003545	ACT binding site; other site
526224003546	IMP binding site; other site
526224003547	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003548	binding surface
526224003549	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224003550	TPR motif; other site
526224003551	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003552	TPR motif; other site
526224003553	TPR repeat; Region: TPR_11; pfam13414
526224003554	binding surface
526224003555	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003556	binding surface
526224003557	TPR repeat; Region: TPR_11; pfam13414
526224003558	TPR motif; other site
526224003559	TPR repeat; Region: TPR_11; pfam13414
526224003560	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003561	binding surface
526224003562	TPR motif; other site
526224003563	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003564	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224003565	Walker A motif; other site
526224003566	ATP binding site [chemical binding]; other site
526224003567	Walker B motif; other site
526224003568	arginine finger; other site
526224003569	5-methylcytosine-specific restriction enzyme subunit McrC; Provisional; Region: PRK09736
526224003570	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224003571	TPR motif; other site
526224003572	binding surface
526224003573	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
526224003574	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
526224003575	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
526224003576	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
526224003577	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
526224003578	active site
526224003579	catalytic residues [active]
526224003580	DNA binding site [nucleotide binding]
526224003581	Int/Topo IB signature motif; other site
526224003582	Predicted chitinase [General function prediction only]; Region: COG3179
526224003583	catalytic residue [active]
526224003584	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
526224003585	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
526224003586	DNA binding residues [nucleotide binding]
526224003587	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
526224003588	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
526224003589	oligomerization interface [polypeptide binding]; other site
526224003590	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
526224003591	Phage capsid family; Region: Phage_capsid; pfam05065
526224003592	Phage portal protein; Region: Phage_portal; pfam04860
526224003593	Phage-related protein [Function unknown]; Region: COG4695
526224003594	Phage terminase, small subunit; Region: Terminase_4; cl01525
526224003595	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
526224003596	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
526224003597	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
526224003598	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
526224003599	active site
526224003600	catalytic residues [active]
526224003601	DNA binding site [nucleotide binding]
526224003602	Int/Topo IB signature motif; other site
526224003603	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
526224003604	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
526224003605	dimer interface [polypeptide binding]; other site
526224003606	ssDNA binding site [nucleotide binding]; other site
526224003607	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224003608	ribonuclease Y; Region: RNase_Y; TIGR03319
526224003609	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
526224003610	active site
526224003611	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224003612	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224003613	Walker A motif; other site
526224003614	ATP binding site [chemical binding]; other site
526224003615	Walker B motif; other site
526224003616	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
526224003617	Rubredoxin [Energy production and conversion]; Region: COG1773
526224003618	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
526224003619	iron binding site [ion binding]; other site
526224003620	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
526224003621	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
526224003622	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
526224003623	alanine racemase; Reviewed; Region: alr; PRK00053
526224003624	active site
526224003625	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
526224003626	dimer interface [polypeptide binding]; other site
526224003627	substrate binding site [chemical binding]; other site
526224003628	catalytic residues [active]
526224003629	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003630	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003631	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003632	dimer interface [polypeptide binding]; other site
526224003633	putative CheW interface [polypeptide binding]; other site
526224003634	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
526224003635	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
526224003636	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
526224003637	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
526224003638	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
526224003639	hinge; other site
526224003640	active site
526224003641	DHH family; Region: DHH; pfam01368
526224003642	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
526224003643	DHHA1 domain; Region: DHHA1; pfam02272
526224003644	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003645	TPR motif; other site
526224003646	binding surface
526224003647	TPR repeat; Region: TPR_11; pfam13414
526224003648	TPR repeat; Region: TPR_11; pfam13414
526224003649	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003650	binding surface
526224003651	TPR motif; other site
526224003652	TPR repeat; Region: TPR_11; pfam13414
526224003653	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003654	binding surface
526224003655	TPR repeat; Region: TPR_11; pfam13414
526224003656	TPR motif; other site
526224003657	TPR repeat; Region: TPR_11; pfam13414
526224003658	TPR repeat; Region: TPR_11; pfam13414
526224003659	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003660	TPR motif; other site
526224003661	TPR repeat; Region: TPR_11; pfam13414
526224003662	binding surface
526224003663	TPR repeat; Region: TPR_11; pfam13414
526224003664	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003665	binding surface
526224003666	TPR motif; other site
526224003667	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003668	binding surface
526224003669	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224003670	TPR motif; other site
526224003671	TPR repeat; Region: TPR_11; pfam13414
526224003672	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003673	binding surface
526224003674	TPR motif; other site
526224003675	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
526224003676	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224003677	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
526224003678	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003679	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003680	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003681	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003682	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003683	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
526224003684	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003685	Ankyrin repeat; Region: Ank; pfam00023
526224003686	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003687	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003688	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003689	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003690	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
526224003691	active site
526224003692	NTP binding site [chemical binding]; other site
526224003693	metal binding triad [ion binding]; metal-binding site
526224003694	antibiotic binding site [chemical binding]; other site
526224003695	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
526224003696	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
526224003697	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
526224003698	putative active site [active]
526224003699	PhoH-like protein; Region: PhoH; pfam02562
526224003700	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224003701	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224003702	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
526224003703	active site
526224003704	substrate binding site [chemical binding]; other site
526224003705	trimer interface [polypeptide binding]; other site
526224003706	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
526224003707	CoA binding site [chemical binding]; other site
526224003708	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
526224003709	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
526224003710	Transcriptional regulator [Transcription]; Region: LysR; COG0583
526224003711	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
526224003712	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
526224003713	dimerization interface [polypeptide binding]; other site
526224003714	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
526224003715	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
526224003716	Cache domain; Region: Cache_1; pfam02743
526224003717	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003718	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003719	dimer interface [polypeptide binding]; other site
526224003720	putative CheW interface [polypeptide binding]; other site
526224003721	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
526224003722	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
526224003723	metal ion-dependent adhesion site (MIDAS); other site
526224003724	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003725	binding surface
526224003726	TPR repeat; Region: TPR_11; pfam13414
526224003727	TPR motif; other site
526224003728	TPR repeat; Region: TPR_11; pfam13414
526224003729	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003730	binding surface
526224003731	TPR motif; other site
526224003732	TPR repeat; Region: TPR_11; pfam13414
526224003733	TPR repeat; Region: TPR_11; pfam13414
526224003734	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003735	binding surface
526224003736	TPR motif; other site
526224003737	TPR repeat; Region: TPR_11; pfam13414
526224003738	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
526224003739	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
526224003740	Thymidine kinase; Region: TK; pfam00265
526224003741	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
526224003742	Family of unknown function (DUF438); Region: DUF438; pfam04282
526224003743	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
526224003744	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
526224003745	dimerization interface [polypeptide binding]; other site
526224003746	putative active cleft [active]
526224003747	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
526224003748	DNA methylase; Region: N6_N4_Mtase; pfam01555
526224003749	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
526224003750	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
526224003751	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
526224003752	active site
526224003753	HIGH motif; other site
526224003754	KMSK motif region; other site
526224003755	tRNA binding surface [nucleotide binding]; other site
526224003756	DALR anticodon binding domain; Region: DALR_1; smart00836
526224003757	anticodon binding site; other site
526224003758	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224003759	active site
526224003760	phosphorylation site [posttranslational modification]
526224003761	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
526224003762	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
526224003763	Ligand binding site; other site
526224003764	oligomer interface; other site
526224003765	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
526224003766	putative deacylase active site [active]
526224003767	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
526224003768	NADP(H)-dependent alcohol dehydrogenases; Region: NADP_ADH; cd08285
526224003769	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
526224003770	tetramer interface [polypeptide binding]; other site
526224003771	catalytic Zn binding site [ion binding]; other site
526224003772	NADP binding site [chemical binding]; other site
526224003773	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224003774	dimerization interface [polypeptide binding]; other site
526224003775	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003776	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003777	dimer interface [polypeptide binding]; other site
526224003778	putative CheW interface [polypeptide binding]; other site
526224003779	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH1; cd08185
526224003780	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
526224003781	putative active site [active]
526224003782	metal binding site [ion binding]; metal-binding site
526224003783	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
526224003784	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
526224003785	NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179
526224003786	putative active site [active]
526224003787	metal binding site [ion binding]; metal-binding site
526224003788	TonB C terminal; Region: TonB_2; pfam13103
526224003789	Predicted methyltransferases [General function prediction only]; Region: COG0313
526224003790	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
526224003791	putative SAM binding site [chemical binding]; other site
526224003792	putative homodimer interface [polypeptide binding]; other site
526224003793	phenylalanine 4-monooxygenase; Provisional; Region: PRK14056
526224003794	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
526224003795	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
526224003796	DNA binding residues [nucleotide binding]
526224003797	dimerization interface [polypeptide binding]; other site
526224003798	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
526224003799	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
526224003800	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
526224003801	putative active site [active]
526224003802	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003803	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003804	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003805	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003806	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003807	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
526224003808	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
526224003809	CoA binding domain; Region: CoA_binding; smart00881
526224003810	NAD-dependent deacetylase; Provisional; Region: PRK00481
526224003811	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
526224003812	Hemerythrin; Region: Hemerythrin; cd12107
526224003813	Fe binding site [ion binding]; other site
526224003814	Hemerythrin; Region: Hemerythrin; cd12107
526224003815	Fe binding site [ion binding]; other site
526224003816	Hemerythrin; Region: Hemerythrin; cd12107
526224003817	Fe binding site [ion binding]; other site
526224003818	enolase; Provisional; Region: eno; PRK00077
526224003819	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
526224003820	dimer interface [polypeptide binding]; other site
526224003821	metal binding site [ion binding]; metal-binding site
526224003822	substrate binding pocket [chemical binding]; other site
526224003823	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
526224003824	catalytic core [active]
526224003825	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
526224003826	putative septicolysin, cholesterol-dependent cytolysin family and related proteins; Region: septicolysin_like; cd12208
526224003827	oligomer interface [polypeptide binding]; other site
526224003828	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
526224003829	Predicted chitinase [General function prediction only]; Region: COG3179
526224003830	catalytic residue [active]
526224003831	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224003832	dimerization interface [polypeptide binding]; other site
526224003833	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003834	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003835	dimer interface [polypeptide binding]; other site
526224003836	putative CheW interface [polypeptide binding]; other site
526224003837	HAMP domain; Region: HAMP; pfam00672
526224003838	dimerization interface [polypeptide binding]; other site
526224003839	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224003840	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224003841	dimer interface [polypeptide binding]; other site
526224003842	putative CheW interface [polypeptide binding]; other site
526224003843	GTP-binding protein Der; Reviewed; Region: PRK00093
526224003844	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
526224003845	G1 box; other site
526224003846	GTP/Mg2+ binding site [chemical binding]; other site
526224003847	Switch I region; other site
526224003848	G2 box; other site
526224003849	Switch II region; other site
526224003850	G3 box; other site
526224003851	G4 box; other site
526224003852	G5 box; other site
526224003853	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
526224003854	G1 box; other site
526224003855	GTP/Mg2+ binding site [chemical binding]; other site
526224003856	Switch I region; other site
526224003857	G2 box; other site
526224003858	G3 box; other site
526224003859	Switch II region; other site
526224003860	G4 box; other site
526224003861	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; pfam02660
526224003862	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
526224003863	Domain of unknown function (DUF2828); Region: DUF2828; pfam11443
526224003864	Domain of unknown function (DUF955); Region: DUF955; cl01076
526224003865	inositol-tetrakisphosphate 1-kinase; Region: PLN02941
526224003866	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
526224003867	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
526224003868	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
526224003869	homodimer interface [polypeptide binding]; other site
526224003870	NADP binding site [chemical binding]; other site
526224003871	substrate binding site [chemical binding]; other site
526224003872	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224003873	TPR repeat; Region: TPR_11; pfam13414
526224003874	binding surface
526224003875	TPR motif; other site
526224003876	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224003877	binding surface
526224003878	TPR motif; other site
526224003879	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
526224003880	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
526224003881	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224003882	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224003883	peptide binding site [polypeptide binding]; other site
526224003884	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
526224003885	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
526224003886	substrate binding site [chemical binding]; other site
526224003887	glutamase interaction surface [polypeptide binding]; other site
526224003888	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003889	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003890	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003891	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003892	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
526224003893	Ankyrin repeat; Region: Ank; pfam00023
526224003894	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003895	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003896	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003897	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003898	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003899	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003900	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224003901	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
526224003902	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224003903	AAA domain; Region: AAA_21; pfam13304
526224003904	Walker A/P-loop; other site
526224003905	ATP binding site [chemical binding]; other site
526224003906	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
526224003907	Walker B; other site
526224003908	D-loop; other site
526224003909	H-loop/switch region; other site
526224003910	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
526224003911	Peptidase family U32; Region: Peptidase_U32; pfam01136
526224003912	Collagenase; Region: DUF3656; pfam12392
526224003913	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
526224003914	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003915	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003916	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
526224003917	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003918	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003919	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
526224003920	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224003921	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224003922	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224003923	Double zinc ribbon; Region: DZR; pfam12773
526224003924	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
526224003925	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
526224003926	hypothetical protein; Region: PHA00684
526224003927	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
526224003928	Ligand binding site; other site
526224003929	Putative Catalytic site; other site
526224003930	DXD motif; other site
526224003931	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224003932	active site
526224003933	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
526224003934	Ligand binding site; other site
526224003935	Putative Catalytic site; other site
526224003936	DXD motif; other site
526224003937	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
526224003938	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
526224003939	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224003940	NAD(P) binding site [chemical binding]; other site
526224003941	active site
526224003942	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
526224003943	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
526224003944	Ligand binding site; other site
526224003945	Putative Catalytic site; other site
526224003946	DXD motif; other site
526224003947	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
526224003948	active site
526224003949	intersubunit interactions; other site
526224003950	catalytic residue [active]
526224003951	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
526224003952	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
526224003953	nucleotide binding pocket [chemical binding]; other site
526224003954	K-X-D-G motif; other site
526224003955	catalytic site [active]
526224003956	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
526224003957	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
526224003958	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
526224003959	Dimer interface [polypeptide binding]; other site
526224003960	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
526224003961	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
526224003962	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
526224003963	dimer interface [polypeptide binding]; other site
526224003964	anticodon binding site; other site
526224003965	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
526224003966	homodimer interface [polypeptide binding]; other site
526224003967	motif 1; other site
526224003968	active site
526224003969	motif 2; other site
526224003970	GAD domain; Region: GAD; pfam02938
526224003971	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
526224003972	active site
526224003973	motif 3; other site
526224003974	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
526224003975	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
526224003976	Walker A/P-loop; other site
526224003977	ATP binding site [chemical binding]; other site
526224003978	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
526224003979	ABC transporter signature motif; other site
526224003980	Walker B; other site
526224003981	D-loop; other site
526224003982	H-loop/switch region; other site
526224003983	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224003984	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224003985	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
526224003986	Part of AAA domain; Region: AAA_19; pfam13245
526224003987	Family description; Region: UvrD_C_2; pfam13538
526224003988	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
526224003989	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
526224003990	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
526224003991	protein binding site [polypeptide binding]; other site
526224003992	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
526224003993	Catalytic dyad [active]
526224003994	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224003995	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224003996	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224003997	seryl-tRNA synthetase; Provisional; Region: PRK05431
526224003998	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
526224003999	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
526224004000	dimer interface [polypeptide binding]; other site
526224004001	active site
526224004002	motif 1; other site
526224004003	motif 2; other site
526224004004	motif 3; other site
526224004005	recombination factor protein RarA; Reviewed; Region: PRK13342
526224004006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224004007	Walker A motif; other site
526224004008	ATP binding site [chemical binding]; other site
526224004009	Walker B motif; other site
526224004010	arginine finger; other site
526224004011	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
526224004012	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224004013	dimerization interface [polypeptide binding]; other site
526224004014	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224004015	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004016	dimer interface [polypeptide binding]; other site
526224004017	putative CheW interface [polypeptide binding]; other site
526224004018	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
526224004019	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
526224004020	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
526224004021	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
526224004022	Walker A/P-loop; other site
526224004023	ATP binding site [chemical binding]; other site
526224004024	Q-loop/lid; other site
526224004025	ABC transporter signature motif; other site
526224004026	Walker B; other site
526224004027	D-loop; other site
526224004028	H-loop/switch region; other site
526224004029	NIL domain; Region: NIL; pfam09383
526224004030	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224004031	dimer interface [polypeptide binding]; other site
526224004032	conserved gate region; other site
526224004033	ABC-ATPase subunit interface; other site
526224004034	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
526224004035	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224004036	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
526224004037	NAD binding site [chemical binding]; other site
526224004038	dimer interface [polypeptide binding]; other site
526224004039	substrate binding site [chemical binding]; other site
526224004040	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
526224004041	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
526224004042	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
526224004043	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
526224004044	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
526224004045	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
526224004046	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
526224004047	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
526224004048	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
526224004049	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
526224004050	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
526224004051	substrate binding pocket [chemical binding]; other site
526224004052	catalytic triad [active]
526224004053	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
526224004054	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
526224004055	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
526224004056	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
526224004057	putative active site [active]
526224004058	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
526224004059	uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334
526224004060	Na2 binding site [ion binding]; other site
526224004061	putative substrate binding site 1 [chemical binding]; other site
526224004062	Na binding site 1 [ion binding]; other site
526224004063	putative substrate binding site 2 [chemical binding]; other site
526224004064	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
526224004065	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
526224004066	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
526224004067	dimerization interface [polypeptide binding]; other site
526224004068	active site
526224004069	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
526224004070	Lumazine binding domain; Region: Lum_binding; pfam00677
526224004071	Lumazine binding domain; Region: Lum_binding; pfam00677
526224004072	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
526224004073	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
526224004074	catalytic motif [active]
526224004075	Zn binding site [ion binding]; other site
526224004076	RibD C-terminal domain; Region: RibD_C; cl17279
526224004077	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
526224004078	additional DNA contacts [nucleotide binding]; other site
526224004079	mismatch recognition site; other site
526224004080	active site
526224004081	zinc binding site [ion binding]; other site
526224004082	DNA intercalation site [nucleotide binding]; other site
526224004083	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
526224004084	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
526224004085	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
526224004086	cofactor binding site; other site
526224004087	DNA binding site [nucleotide binding]
526224004088	substrate interaction site [chemical binding]; other site
526224004089	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
526224004090	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004091	binding surface
526224004092	TPR motif; other site
526224004093	TPR repeat; Region: TPR_11; pfam13414
526224004094	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224004095	AAA domain; Region: AAA_21; pfam13304
526224004096	Walker A/P-loop; other site
526224004097	ATP binding site [chemical binding]; other site
526224004098	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
526224004099	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
526224004100	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
526224004101	metal-binding site [ion binding]
526224004102	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
526224004103	Soluble P-type ATPase [General function prediction only]; Region: COG4087
526224004104	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
526224004105	Predicted Zn-dependent protease (DUF2268); Region: DUF2268; cl02316
526224004106	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
526224004107	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224004108	Walker A motif; other site
526224004109	ATP binding site [chemical binding]; other site
526224004110	Walker B motif; other site
526224004111	arginine finger; other site
526224004112	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
526224004113	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
526224004114	Response regulator receiver domain; Region: Response_reg; pfam00072
526224004115	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224004116	active site
526224004117	phosphorylation site [posttranslational modification]
526224004118	intermolecular recognition site; other site
526224004119	dimerization interface [polypeptide binding]; other site
526224004120	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
526224004121	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
526224004122	metal binding site [ion binding]; metal-binding site
526224004123	active site
526224004124	I-site; other site
526224004125	Uncharacterized conserved protein [Function unknown]; Region: COG4938
526224004126	aspartate kinase; Reviewed; Region: PRK09034
526224004127	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
526224004128	nucleotide binding site [chemical binding]; other site
526224004129	substrate binding site [chemical binding]; other site
526224004130	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
526224004131	allosteric regulatory residue; other site
526224004132	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
526224004133	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
526224004134	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
526224004135	putative NAD(P) binding site [chemical binding]; other site
526224004136	putative substrate binding site [chemical binding]; other site
526224004137	catalytic Zn binding site [ion binding]; other site
526224004138	structural Zn binding site [ion binding]; other site
526224004139	dimer interface [polypeptide binding]; other site
526224004140	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
526224004141	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
526224004142	NAD(P) binding site [chemical binding]; other site
526224004143	homodimer interface [polypeptide binding]; other site
526224004144	substrate binding site [chemical binding]; other site
526224004145	active site
526224004146	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224004147	active site
526224004148	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
526224004149	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
526224004150	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
526224004151	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
526224004152	Ligand binding site [chemical binding]; other site
526224004153	Electron transfer flavoprotein domain; Region: ETF; pfam01012
526224004154	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
526224004155	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
526224004156	FAD binding site [chemical binding]; other site
526224004157	homotetramer interface [polypeptide binding]; other site
526224004158	substrate binding pocket [chemical binding]; other site
526224004159	catalytic base [active]
526224004160	Coenzyme A transferase; Region: CoA_trans; smart00882
526224004161	Coenzyme A transferase; Region: CoA_trans; cl17247
526224004162	V-type ATP synthase subunit E; Provisional; Region: PRK01005
526224004163	V-type ATP synthase subunit E; Provisional; Region: PRK01558
526224004164	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
526224004165	V-type ATP synthase subunit A; Provisional; Region: PRK04192
526224004166	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
526224004167	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
526224004168	Walker A motif/ATP binding site; other site
526224004169	Walker B motif; other site
526224004170	V-type ATP synthase subunit B; Provisional; Region: PRK02118
526224004171	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
526224004172	Walker A motif homologous position; other site
526224004173	Walker B motif; other site
526224004174	V-type ATP synthase subunit D; Provisional; Region: PRK02195
526224004175	V-type ATP synthase subunit I; Validated; Region: PRK05771
526224004176	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
526224004177	V-type ATP synthase subunit K; Provisional; Region: PRK09621
526224004178	cytosolic glyceraldehyde 3-phosphate dehydrogenase; Provisional; Region: PTZ00434
526224004179	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
526224004180	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
526224004181	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
526224004182	Phosphoglycerate kinase; Region: PGK; pfam00162
526224004183	substrate binding site [chemical binding]; other site
526224004184	hinge regions; other site
526224004185	ADP binding site [chemical binding]; other site
526224004186	catalytic site [active]
526224004187	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
526224004188	heterotetramer interface [polypeptide binding]; other site
526224004189	active site pocket [active]
526224004190	cleavage site
526224004191	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
526224004192	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
526224004193	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
526224004194	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
526224004195	Walker A motif; other site
526224004196	ATP binding site [chemical binding]; other site
526224004197	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
526224004198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
526224004199	GTP-binding protein LepA; Provisional; Region: PRK05433
526224004200	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
526224004201	G1 box; other site
526224004202	putative GEF interaction site [polypeptide binding]; other site
526224004203	GTP/Mg2+ binding site [chemical binding]; other site
526224004204	Switch I region; other site
526224004205	G2 box; other site
526224004206	G3 box; other site
526224004207	Switch II region; other site
526224004208	G4 box; other site
526224004209	G5 box; other site
526224004210	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
526224004211	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
526224004212	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
526224004213	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
526224004214	Methyltransferase domain; Region: Methyltransf_26; pfam13659
526224004215	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
526224004216	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
526224004217	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
526224004218	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224004219	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224004220	substrate binding pocket [chemical binding]; other site
526224004221	membrane-bound complex binding site; other site
526224004222	hinge residues; other site
526224004223	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224004224	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224004225	substrate binding pocket [chemical binding]; other site
526224004226	membrane-bound complex binding site; other site
526224004227	hinge residues; other site
526224004228	SWIM zinc finger; Region: SWIM; pfam04434
526224004229	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224004230	AAA domain; Region: AAA_21; pfam13304
526224004231	Walker A/P-loop; other site
526224004232	ATP binding site [chemical binding]; other site
526224004233	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
526224004234	Protein export membrane protein; Region: SecD_SecF; cl14618
526224004235	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
526224004236	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
526224004237	Preprotein translocase subunit; Region: YajC; pfam02699
526224004238	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
526224004239	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
526224004240	substrate binding pocket [chemical binding]; other site
526224004241	membrane-bound complex binding site; other site
526224004242	hinge residues; other site
526224004243	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
526224004244	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
526224004245	Walker A/P-loop; other site
526224004246	ATP binding site [chemical binding]; other site
526224004247	Q-loop/lid; other site
526224004248	ABC transporter signature motif; other site
526224004249	Walker B; other site
526224004250	D-loop; other site
526224004251	H-loop/switch region; other site
526224004252	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
526224004253	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224004254	dimer interface [polypeptide binding]; other site
526224004255	conserved gate region; other site
526224004256	putative PBP binding loops; other site
526224004257	ABC-ATPase subunit interface; other site
526224004258	Uncharacterized conserved protein [Function unknown]; Region: COG1432
526224004259	LabA_like proteins; Region: LabA_like; cd06167
526224004260	putative metal binding site [ion binding]; other site
526224004261	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
526224004262	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
526224004263	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224004264	Protein export membrane protein; Region: SecD_SecF; cl14618
526224004265	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
526224004266	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
526224004267	HlyD family secretion protein; Region: HlyD_3; pfam13437
526224004268	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
526224004269	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224004270	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
526224004271	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224004272	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
526224004273	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224004274	NAD(P) binding site [chemical binding]; other site
526224004275	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224004276	NAD(P) binding site [chemical binding]; other site
526224004277	active site
526224004278	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224004279	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
526224004280	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
526224004281	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224004282	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224004283	peptide binding site [polypeptide binding]; other site
526224004284	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224004285	peptide binding site [polypeptide binding]; other site
526224004286	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
526224004287	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
526224004288	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
526224004289	SmpB-tmRNA interface; other site
526224004290	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
526224004291	oligomerisation interface [polypeptide binding]; other site
526224004292	mobile loop; other site
526224004293	roof hairpin; other site
526224004294	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224004295	active site
526224004296	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224004297	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
526224004298	Transcriptional regulator; Region: Rrf2; pfam02082
526224004299	Rrf2 family protein; Region: rrf2_super; TIGR00738
526224004300	hybrid cluster protein; Provisional; Region: PRK05290
526224004301	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
526224004302	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
526224004303	hybrid metal cluster; other site
526224004304	Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair]; Region: COG1525
526224004305	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
526224004306	thiamine phosphate binding site [chemical binding]; other site
526224004307	active site
526224004308	pyrophosphate binding site [ion binding]; other site
526224004309	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224004310	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224004311	peptide binding site [polypeptide binding]; other site
526224004312	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004313	binding surface
526224004314	TPR repeat; Region: TPR_11; pfam13414
526224004315	TPR motif; other site
526224004316	TPR repeat; Region: TPR_11; pfam13414
526224004317	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004318	binding surface
526224004319	TPR motif; other site
526224004320	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004321	binding surface
526224004322	TPR repeat; Region: TPR_11; pfam13414
526224004323	TPR motif; other site
526224004324	TPR repeat; Region: TPR_11; pfam13414
526224004325	TPR repeat; Region: TPR_11; pfam13414
526224004326	TPR repeat; Region: TPR_11; pfam13414
526224004327	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004328	binding surface
526224004329	TPR motif; other site
526224004330	TPR repeat; Region: TPR_11; pfam13414
526224004331	TPR repeat; Region: TPR_11; pfam13414
526224004332	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004333	binding surface
526224004334	TPR motif; other site
526224004335	TPR repeat; Region: TPR_11; pfam13414
526224004336	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004337	binding surface
526224004338	TPR motif; other site
526224004339	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224004340	TPR motif; other site
526224004341	binding surface
526224004342	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
526224004343	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
526224004344	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
526224004345	dimer interface [polypeptide binding]; other site
526224004346	PYR/PP interface [polypeptide binding]; other site
526224004347	TPP binding site [chemical binding]; other site
526224004348	substrate binding site [chemical binding]; other site
526224004349	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
526224004350	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
526224004351	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
526224004352	TPP-binding site [chemical binding]; other site
526224004353	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
526224004354	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
526224004355	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224004356	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224004357	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224004358	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224004359	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224004360	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK12911
526224004361	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06665
526224004362	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
526224004363	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
526224004364	Biogenesis of lysosome-related organelles complex-1 subunit 2; Region: BLOC1_2; pfam10046
526224004365	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224004366	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004367	dimer interface [polypeptide binding]; other site
526224004368	putative CheW interface [polypeptide binding]; other site
526224004369	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
526224004370	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224004371	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224004372	homodimer interface [polypeptide binding]; other site
526224004373	catalytic residue [active]
526224004374	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
526224004375	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
526224004376	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
526224004377	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
526224004378	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
526224004379	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
526224004380	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
526224004381	active site
526224004382	Int/Topo IB signature motif; other site
526224004383	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
526224004384	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
526224004385	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224004386	catalytic residue [active]
526224004387	Protein of unknown function (DUF4241); Region: DUF4241; pfam14025
526224004388	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
526224004389	catalytic triad [active]
526224004390	conserved cis-peptide bond; other site
526224004391	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
526224004392	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
526224004393	dimer interface [polypeptide binding]; other site
526224004394	active site
526224004395	CoA binding pocket [chemical binding]; other site
526224004396	Protein of unknown function (DUF4026); Region: DUF4026; pfam13218
526224004397	Protein of unknown function DUF45; Region: DUF45; pfam01863
526224004398	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224004399	dimerization interface [polypeptide binding]; other site
526224004400	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004401	dimer interface [polypeptide binding]; other site
526224004402	putative CheW interface [polypeptide binding]; other site
526224004403	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cl00304
526224004404	active site
526224004405	homodimer interface [polypeptide binding]; other site
526224004406	SAM binding site [chemical binding]; other site
526224004407	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
526224004408	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
526224004409	amidase catalytic site [active]
526224004410	Zn binding residues [ion binding]; other site
526224004411	substrate binding site [chemical binding]; other site
526224004412	RIP metalloprotease RseP; Region: TIGR00054
526224004413	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
526224004414	active site
526224004415	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
526224004416	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
526224004417	protein binding site [polypeptide binding]; other site
526224004418	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
526224004419	putative substrate binding region [chemical binding]; other site
526224004420	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
526224004421	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224004422	FeS/SAM binding site; other site
526224004423	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
526224004424	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; cl02090
526224004425	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
526224004426	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004427	binding surface
526224004428	TPR motif; other site
526224004429	TPR repeat; Region: TPR_11; pfam13414
526224004430	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004431	binding surface
526224004432	TPR motif; other site
526224004433	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224004434	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004435	binding surface
526224004436	TPR motif; other site
526224004437	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
526224004438	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
526224004439	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
526224004440	active site
526224004441	NAD binding site [chemical binding]; other site
526224004442	metal binding site [ion binding]; metal-binding site
526224004443	Predicted exonuclease [DNA replication, recombination, and repair]; Region: COG3359
526224004444	RNase_H superfamily; Region: RNase_H_2; pfam13482
526224004445	active site
526224004446	catalytic site [active]
526224004447	substrate binding site [chemical binding]; other site
526224004448	active site
526224004449	substrate binding site [chemical binding]; other site
526224004450	catalytic site [active]
526224004451	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
526224004452	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
526224004453	active site
526224004454	HIGH motif; other site
526224004455	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
526224004456	KMSKS motif; other site
526224004457	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
526224004458	tRNA binding surface [nucleotide binding]; other site
526224004459	anticodon binding site; other site
526224004460	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
526224004461	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
526224004462	hypothetical protein; Validated; Region: PRK00110
526224004463	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
526224004464	active site
526224004465	putative DNA-binding cleft [nucleotide binding]; other site
526224004466	dimer interface [polypeptide binding]; other site
526224004467	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
526224004468	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
526224004469	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
526224004470	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
526224004471	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004472	binding surface
526224004473	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224004474	TPR motif; other site
526224004475	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224004476	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004477	binding surface
526224004478	TPR motif; other site
526224004479	TPR repeat; Region: TPR_11; pfam13414
526224004480	TPR repeat; Region: TPR_11; pfam13414
526224004481	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004482	binding surface
526224004483	TPR motif; other site
526224004484	TPR repeat; Region: TPR_11; pfam13414
526224004485	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004486	binding surface
526224004487	TPR motif; other site
526224004488	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224004489	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004490	TPR motif; other site
526224004491	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224004492	binding surface
526224004493	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004494	binding surface
526224004495	TPR motif; other site
526224004496	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224004497	Zn2+ binding site [ion binding]; other site
526224004498	Mg2+ binding site [ion binding]; other site
526224004499	Flagellin N-methylase; Region: FliB; pfam03692
526224004500	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
526224004501	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
526224004502	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224004503	S-adenosylmethionine binding site [chemical binding]; other site
526224004504	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
526224004505	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224004506	motif II; other site
526224004507	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
526224004508	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
526224004509	NAD binding site [chemical binding]; other site
526224004510	homodimer interface [polypeptide binding]; other site
526224004511	active site
526224004512	substrate binding site [chemical binding]; other site
526224004513	Spore germination protein [General function prediction only]; Region: COG5401
526224004514	Sporulation and spore germination; Region: Germane; smart00909
526224004515	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
526224004516	NeuB family; Region: NeuB; pfam03102
526224004517	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
526224004518	NeuB binding interface [polypeptide binding]; other site
526224004519	putative substrate binding site [chemical binding]; other site
526224004520	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
526224004521	FtsX-like permease family; Region: FtsX; pfam02687
526224004522	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
526224004523	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
526224004524	FtsX-like permease family; Region: FtsX; pfam02687
526224004525	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
526224004526	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
526224004527	Walker A/P-loop; other site
526224004528	ATP binding site [chemical binding]; other site
526224004529	Q-loop/lid; other site
526224004530	ABC transporter signature motif; other site
526224004531	Walker B; other site
526224004532	D-loop; other site
526224004533	H-loop/switch region; other site
526224004534	Flavoprotein; Region: Flavoprotein; pfam02441
526224004535	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
526224004536	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
526224004537	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
526224004538	PhoH-like protein; Region: PhoH; pfam02562
526224004539	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
526224004540	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
526224004541	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224004542	Zn2+ binding site [ion binding]; other site
526224004543	Mg2+ binding site [ion binding]; other site
526224004544	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
526224004545	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
526224004546	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
526224004547	Transporter associated domain; Region: CorC_HlyC; smart01091
526224004548	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224004549	binding surface
526224004550	TPR motif; other site
526224004551	Restriction endonuclease; Region: Mrr_cat; pfam04471
526224004552	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
526224004553	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
526224004554	active site
526224004555	catalytic residues [active]
526224004556	DNA binding site [nucleotide binding]
526224004557	Int/Topo IB signature motif; other site
526224004558	Predicted chitinase [General function prediction only]; Region: COG3179
526224004559	catalytic residue [active]
526224004560	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
526224004561	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
526224004562	DNA binding residues [nucleotide binding]
526224004563	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
526224004564	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
526224004565	oligomerization interface [polypeptide binding]; other site
526224004566	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
526224004567	Phage capsid family; Region: Phage_capsid; pfam05065
526224004568	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
526224004569	Phage portal protein; Region: Phage_portal; pfam04860
526224004570	Phage-related protein [Function unknown]; Region: COG4695
526224004571	Phage terminase, small subunit; Region: Terminase_4; cl01525
526224004572	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
526224004573	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
526224004574	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
526224004575	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
526224004576	active site
526224004577	catalytic residues [active]
526224004578	DNA binding site [nucleotide binding]
526224004579	Int/Topo IB signature motif; other site
526224004580	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
526224004581	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
526224004582	dimer interface [polypeptide binding]; other site
526224004583	ssDNA binding site [nucleotide binding]; other site
526224004584	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224004585	ribonuclease Y; Region: RNase_Y; TIGR03319
526224004586	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
526224004587	active site
526224004588	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224004589	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224004590	Walker A motif; other site
526224004591	ATP binding site [chemical binding]; other site
526224004592	Walker B motif; other site
526224004593	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
526224004594	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
526224004595	putative ligand binding site [chemical binding]; other site
526224004596	putative NAD binding site [chemical binding]; other site
526224004597	catalytic site [active]
526224004598	inner membrane protein; Provisional; Region: PRK11715
526224004599	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224004600	S-adenosylmethionine binding site [chemical binding]; other site
526224004601	ABC transporter substrate binding protein; Region: ABC_sub_bind; cl17301
526224004602	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
526224004603	putative phosphate acyltransferase; Provisional; Region: PRK05331
526224004604	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
526224004605	active site
526224004606	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
526224004607	SLBB domain; Region: SLBB; pfam10531
526224004608	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
526224004609	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
526224004610	FMN-binding domain; Region: FMN_bind; cl01081
526224004611	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224004612	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
526224004613	active site
526224004614	Zn binding site [ion binding]; other site
526224004615	Uncharacterized conserved protein [Function unknown]; Region: COG0432
526224004616	AAA domain; Region: AAA_33; pfam13671
526224004617	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
526224004618	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
526224004619	active site
526224004620	metal binding site [ion binding]; metal-binding site
526224004621	RNA ligase; Region: RNA_lig_T4_1; pfam09511
526224004622	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
526224004623	nudix motif; other site
526224004624	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_3; cd08770
526224004625	SxDxEG motif; other site
526224004626	putative active site [active]
526224004627	putative metal binding site [ion binding]; other site
526224004628	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
526224004629	AAA domain; Region: AAA_21; pfam13304
526224004630	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224004631	Walker B; other site
526224004632	D-loop; other site
526224004633	H-loop/switch region; other site
526224004634	Domain of unknown function (DUF4411); Region: DUF4411; pfam14367
526224004635	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224004636	non-specific DNA binding site [nucleotide binding]; other site
526224004637	salt bridge; other site
526224004638	sequence-specific DNA binding site [nucleotide binding]; other site
526224004639	Domain of unknown function (DUF955); Region: DUF955; cl01076
526224004640	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
526224004641	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
526224004642	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224004643	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224004644	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224004645	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
526224004646	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
526224004647	inhibitor-cofactor binding pocket; inhibition site
526224004648	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224004649	catalytic residue [active]
526224004650	AAA domain; Region: AAA_26; pfam13500
526224004651	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
526224004652	biotin synthase; Region: bioB; TIGR00433
526224004653	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224004654	FeS/SAM binding site; other site
526224004655	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
526224004656	Biotin operon repressor [Transcription]; Region: BirA; COG1654
526224004657	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
526224004658	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
526224004659	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
526224004660	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
526224004661	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
526224004662	carboxyltransferase (CT) interaction site; other site
526224004663	biotinylation site [posttranslational modification]; other site
526224004664	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
526224004665	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
526224004666	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
526224004667	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
526224004668	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
526224004669	metal binding site [ion binding]; metal-binding site
526224004670	dimer interface [polypeptide binding]; other site
526224004671	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
526224004672	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
526224004673	dimer interface [polypeptide binding]; other site
526224004674	active site
526224004675	catalytic residue [active]
526224004676	dihydrodipicolinate reductase; Provisional; Region: PRK00048
526224004677	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
526224004678	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
526224004679	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
526224004680	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
526224004681	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
526224004682	trimer interface [polypeptide binding]; other site
526224004683	active site
526224004684	substrate binding site [chemical binding]; other site
526224004685	CoA binding site [chemical binding]; other site
526224004686	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
526224004687	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224004688	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224004689	homodimer interface [polypeptide binding]; other site
526224004690	catalytic residue [active]
526224004691	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
526224004692	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
526224004693	dimer interface [polypeptide binding]; other site
526224004694	PYR/PP interface [polypeptide binding]; other site
526224004695	TPP binding site [chemical binding]; other site
526224004696	substrate binding site [chemical binding]; other site
526224004697	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
526224004698	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
526224004699	TPP-binding site [chemical binding]; other site
526224004700	putative dimer interface [polypeptide binding]; other site
526224004701	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
526224004702	pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional; Region: PRK14028
526224004703	4Fe-4S binding domain; Region: Fer4_6; pfam12837
526224004704	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224004705	dimerization interface [polypeptide binding]; other site
526224004706	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224004707	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004708	dimer interface [polypeptide binding]; other site
526224004709	putative CheW interface [polypeptide binding]; other site
526224004710	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224004711	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224004712	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224004713	active site
526224004714	catalytic tetrad [active]
526224004715	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
526224004716	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
526224004717	putative substrate binding site [chemical binding]; other site
526224004718	putative ATP binding site [chemical binding]; other site
526224004719	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
526224004720	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004721	binding surface
526224004722	TPR motif; other site
526224004723	Tetratricopeptide repeat; Region: TPR_6; pfam13174
526224004724	AAA ATPase domain; Region: AAA_15; pfam13175
526224004725	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224004726	Q-loop/lid; other site
526224004727	ABC transporter signature motif; other site
526224004728	Walker B; other site
526224004729	D-loop; other site
526224004730	H-loop/switch region; other site
526224004731	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
526224004732	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
526224004733	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
526224004734	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
526224004735	Mg++ binding site [ion binding]; other site
526224004736	putative catalytic motif [active]
526224004737	putative substrate binding site [chemical binding]; other site
526224004738	thymidylate kinase; Validated; Region: tmk; PRK00698
526224004739	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
526224004740	TMP-binding site; other site
526224004741	ATP-binding site [chemical binding]; other site
526224004742	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
526224004743	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
526224004744	dimer interface [polypeptide binding]; other site
526224004745	ssDNA binding site [nucleotide binding]; other site
526224004746	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224004747	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
526224004748	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
526224004749	active site
526224004750	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
526224004751	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
526224004752	flagellin; Provisional; Region: PRK12804
526224004753	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
526224004754	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
526224004755	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
526224004756	TPR repeat; Region: TPR_11; pfam13414
526224004757	TPR repeat; Region: TPR_11; pfam13414
526224004758	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004759	binding surface
526224004760	TPR motif; other site
526224004761	TPR repeat; Region: TPR_11; pfam13414
526224004762	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224004763	binding surface
526224004764	TPR motif; other site
526224004765	TPR repeat; Region: TPR_11; pfam13414
526224004766	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224004767	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224004768	peptide binding site [polypeptide binding]; other site
526224004769	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224004770	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224004771	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224004772	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224004773	Cache domain; Region: Cache_1; pfam02743
526224004774	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224004775	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004776	dimer interface [polypeptide binding]; other site
526224004777	putative CheW interface [polypeptide binding]; other site
526224004778	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
526224004779	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
526224004780	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
526224004781	trimer interface [polypeptide binding]; other site
526224004782	active site
526224004783	UDP-GlcNAc binding site [chemical binding]; other site
526224004784	lipid binding site [chemical binding]; lipid-binding site
526224004785	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
526224004786	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
526224004787	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
526224004788	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
526224004789	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
526224004790	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
526224004791	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
526224004792	Surface antigen; Region: Bac_surface_Ag; pfam01103
526224004793	Family of unknown function (DUF490); Region: DUF490; pfam04357
526224004794	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224004795	active site
526224004796	phosphorylation site [posttranslational modification]
526224004797	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
526224004798	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224004799	active site
526224004800	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
526224004801	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
526224004802	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
526224004803	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
526224004804	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
526224004805	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
526224004806	Ligand Binding Site [chemical binding]; other site
526224004807	TilS substrate C-terminal domain; Region: TilS_C; smart00977
526224004808	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
526224004809	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
526224004810	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
526224004811	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
526224004812	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
526224004813	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
526224004814	catalytic core [active]
526224004815	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
526224004816	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
526224004817	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
526224004818	HAMP domain; Region: HAMP; pfam00672
526224004819	dimerization interface [polypeptide binding]; other site
526224004820	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224004821	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224004822	dimer interface [polypeptide binding]; other site
526224004823	putative CheW interface [polypeptide binding]; other site
526224004824	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
526224004825	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224004826	Walker A/P-loop; other site
526224004827	ATP binding site [chemical binding]; other site
526224004828	Q-loop/lid; other site
526224004829	ABC transporter signature motif; other site
526224004830	Walker B; other site
526224004831	D-loop; other site
526224004832	H-loop/switch region; other site
526224004833	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
526224004834	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
526224004835	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
526224004836	metal binding site [ion binding]; metal-binding site
526224004837	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
526224004838	S17 interaction site [polypeptide binding]; other site
526224004839	S8 interaction site; other site
526224004840	16S rRNA interaction site [nucleotide binding]; other site
526224004841	streptomycin interaction site [chemical binding]; other site
526224004842	23S rRNA interaction site [nucleotide binding]; other site
526224004843	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
526224004844	30S ribosomal protein S7; Validated; Region: PRK05302
526224004845	elongation factor G; Reviewed; Region: PRK00007
526224004846	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
526224004847	G1 box; other site
526224004848	putative GEF interaction site [polypeptide binding]; other site
526224004849	GTP/Mg2+ binding site [chemical binding]; other site
526224004850	Switch I region; other site
526224004851	G2 box; other site
526224004852	G3 box; other site
526224004853	Switch II region; other site
526224004854	G4 box; other site
526224004855	G5 box; other site
526224004856	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
526224004857	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
526224004858	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
526224004859	elongation factor Tu; Reviewed; Region: PRK00049
526224004860	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
526224004861	G1 box; other site
526224004862	GEF interaction site [polypeptide binding]; other site
526224004863	GTP/Mg2+ binding site [chemical binding]; other site
526224004864	Switch I region; other site
526224004865	G2 box; other site
526224004866	G3 box; other site
526224004867	Switch II region; other site
526224004868	G4 box; other site
526224004869	G5 box; other site
526224004870	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
526224004871	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
526224004872	Antibiotic Binding Site [chemical binding]; other site
526224004873	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
526224004874	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
526224004875	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
526224004876	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
526224004877	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
526224004878	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
526224004879	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
526224004880	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
526224004881	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
526224004882	putative translocon binding site; other site
526224004883	protein-rRNA interface [nucleotide binding]; other site
526224004884	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
526224004885	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
526224004886	G-X-X-G motif; other site
526224004887	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
526224004888	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
526224004889	23S rRNA interface [nucleotide binding]; other site
526224004890	5S rRNA interface [nucleotide binding]; other site
526224004891	putative antibiotic binding site [chemical binding]; other site
526224004892	L25 interface [polypeptide binding]; other site
526224004893	L27 interface [polypeptide binding]; other site
526224004894	50S ribosomal protein L29; Reviewed; Region: PRK00306
526224004895	L23 interface [polypeptide binding]; other site
526224004896	trigger factor interaction site; other site
526224004897	23S rRNA interface [nucleotide binding]; other site
526224004898	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
526224004899	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
526224004900	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
526224004901	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
526224004902	RNA binding site [nucleotide binding]; other site
526224004903	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
526224004904	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
526224004905	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
526224004906	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
526224004907	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
526224004908	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
526224004909	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
526224004910	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
526224004911	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
526224004912	5S rRNA interface [nucleotide binding]; other site
526224004913	23S rRNA interface [nucleotide binding]; other site
526224004914	L5 interface [polypeptide binding]; other site
526224004915	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
526224004916	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
526224004917	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
526224004918	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
526224004919	23S rRNA binding site [nucleotide binding]; other site
526224004920	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
526224004921	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
526224004922	SecY translocase; Region: SecY; pfam00344
526224004923	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
526224004924	rRNA binding site [nucleotide binding]; other site
526224004925	predicted 30S ribosome binding site; other site
526224004926	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
526224004927	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
526224004928	30S ribosomal protein S13; Region: bact_S13; TIGR03631
526224004929	30S ribosomal protein S11; Validated; Region: PRK05309
526224004930	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
526224004931	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
526224004932	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224004933	RNA binding surface [nucleotide binding]; other site
526224004934	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
526224004935	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
526224004936	alphaNTD homodimer interface [polypeptide binding]; other site
526224004937	alphaNTD - beta interaction site [polypeptide binding]; other site
526224004938	alphaNTD - beta' interaction site [polypeptide binding]; other site
526224004939	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
526224004940	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
526224004941	transcription termination factor Rho; Provisional; Region: rho; PRK09376
526224004942	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
526224004943	RNA binding site [nucleotide binding]; other site
526224004944	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
526224004945	Walker A motif; other site
526224004946	ATP binding site [chemical binding]; other site
526224004947	Walker B motif; other site
526224004948	Smr domain; Region: Smr; pfam01713
526224004949	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
526224004950	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
526224004951	Walker A/P-loop; other site
526224004952	ATP binding site [chemical binding]; other site
526224004953	Q-loop/lid; other site
526224004954	ABC transporter signature motif; other site
526224004955	Walker B; other site
526224004956	D-loop; other site
526224004957	H-loop/switch region; other site
526224004958	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
526224004959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224004960	dimer interface [polypeptide binding]; other site
526224004961	conserved gate region; other site
526224004962	putative PBP binding loops; other site
526224004963	ABC-ATPase subunit interface; other site
526224004964	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224004965	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224004966	substrate binding pocket [chemical binding]; other site
526224004967	membrane-bound complex binding site; other site
526224004968	hinge residues; other site
526224004969	LemA family; Region: LemA; cl00742
526224004970	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
526224004971	DNA binding site [nucleotide binding]
526224004972	domain linker motif; other site
526224004973	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
526224004974	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
526224004975	ligand binding site [chemical binding]; other site
526224004976	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
526224004977	ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222
526224004978	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
526224004979	FAD binding pocket [chemical binding]; other site
526224004980	FAD binding motif [chemical binding]; other site
526224004981	phosphate binding motif [ion binding]; other site
526224004982	beta-alpha-beta structure motif; other site
526224004983	NAD binding pocket [chemical binding]; other site
526224004984	Iron coordination center [ion binding]; other site
526224004985	Mrr N-terminal domain; Region: Mrr_N; pfam14338
526224004986	Restriction endonuclease; Region: Mrr_cat; pfam04471
526224004987	thiamine monophosphate kinase; Provisional; Region: PRK05731
526224004988	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
526224004989	ATP binding site [chemical binding]; other site
526224004990	dimerization interface [polypeptide binding]; other site
526224004991	putative acyltransferase; Provisional; Region: PRK05790
526224004992	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
526224004993	dimer interface [polypeptide binding]; other site
526224004994	active site
526224004995	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
526224004996	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
526224004997	metal binding site [ion binding]; metal-binding site
526224004998	dimer interface [polypeptide binding]; other site
526224004999	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224005000	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
526224005001	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224005002	active site
526224005003	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
526224005004	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
526224005005	PIN domain; Region: PIN_Smg5-Smg6-like; cd09880
526224005006	putative active site [active]
526224005007	AAA domain; Region: AAA_11; pfam13086
526224005008	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224005009	ATP binding site [chemical binding]; other site
526224005010	AAA domain; Region: AAA_30; pfam13604
526224005011	AAA domain; Region: AAA_12; pfam13087
526224005012	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
526224005013	CoenzymeA binding site [chemical binding]; other site
526224005014	subunit interaction site [polypeptide binding]; other site
526224005015	PHB binding site; other site
526224005016	YtxH-like protein; Region: YtxH; pfam12732
526224005017	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
526224005018	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
526224005019	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224005020	active site
526224005021	HIGH motif; other site
526224005022	nucleotide binding site [chemical binding]; other site
526224005023	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
526224005024	active site
526224005025	KMSKS motif; other site
526224005026	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
526224005027	tRNA binding surface [nucleotide binding]; other site
526224005028	anticodon binding site; other site
526224005029	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
526224005030	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
526224005031	Part of AAA domain; Region: AAA_19; pfam13245
526224005032	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
526224005033	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
526224005034	Family description; Region: UvrD_C_2; pfam13538
526224005035	AAA ATPase domain; Region: AAA_15; pfam13175
526224005036	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005037	Walker A/P-loop; other site
526224005038	ATP binding site [chemical binding]; other site
526224005039	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
526224005040	putative active site [active]
526224005041	putative metal-binding site [ion binding]; other site
526224005042	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
526224005043	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
526224005044	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
526224005045	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
526224005046	RES domain; Region: RES; smart00953
526224005047	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
526224005048	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
526224005049	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224005050	non-specific DNA binding site [nucleotide binding]; other site
526224005051	salt bridge; other site
526224005052	sequence-specific DNA binding site [nucleotide binding]; other site
526224005053	Domain of unknown function (DUF955); Region: DUF955; cl01076
526224005054	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
526224005055	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
526224005056	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
526224005057	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
526224005058	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224005059	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
526224005060	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
526224005061	DNA methylase; Region: N6_N4_Mtase; pfam01555
526224005062	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
526224005063	B3/4 domain; Region: B3_4; pfam03483
526224005064	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
526224005065	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
526224005066	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
526224005067	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
526224005068	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
526224005069	catalytic site [active]
526224005070	BNR repeat-like domain; Region: BNR_2; pfam13088
526224005071	Asp-box motif; other site
526224005072	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224005073	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
526224005074	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
526224005075	substrate binding pocket [chemical binding]; other site
526224005076	chain length determination region; other site
526224005077	substrate-Mg2+ binding site; other site
526224005078	catalytic residues [active]
526224005079	aspartate-rich region 1; other site
526224005080	active site lid residues [active]
526224005081	aspartate-rich region 2; other site
526224005082	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
526224005083	Protein of unknown function (DUF2589); Region: DUF2589; pfam11655
526224005084	Protein of unknown function (DUF2589); Region: DUF2589; pfam11655
526224005085	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
526224005086	active site
526224005087	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
526224005088	?-D-glucose-1-phosphatase; Provisional; Region: PRK09456
526224005089	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224005090	dimerization interface [polypeptide binding]; other site
526224005091	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
526224005092	dimer interface [polypeptide binding]; other site
526224005093	phosphorylation site [posttranslational modification]
526224005094	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224005095	ATP binding site [chemical binding]; other site
526224005096	Mg2+ binding site [ion binding]; other site
526224005097	G-X-G motif; other site
526224005098	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
526224005099	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
526224005100	Zn2+ binding site [ion binding]; other site
526224005101	Mg2+ binding site [ion binding]; other site
526224005102	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
526224005103	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
526224005104	SLBB domain; Region: SLBB; pfam10531
526224005105	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224005106	active site
526224005107	Flagellar basal body-associated protein [Cell motility and secretion]; Region: FliL; COG1580
526224005108	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
526224005109	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
526224005110	flagellar motor switch protein; Validated; Region: PRK08119
526224005111	flagellar motor switch protein FliN; Region: fliN; TIGR02480
526224005112	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
526224005113	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
526224005114	active site
526224005115	metal binding site [ion binding]; metal-binding site
526224005116	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224005117	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
526224005118	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
526224005119	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
526224005120	active site
526224005121	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
526224005122	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
526224005123	active site
526224005124	dimer interface [polypeptide binding]; other site
526224005125	motif 2; other site
526224005126	motif 3; other site
526224005127	LrgB-like family; Region: LrgB; pfam04172
526224005128	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
526224005129	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
526224005130	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
526224005131	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
526224005132	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
526224005133	putative homodimer interface [polypeptide binding]; other site
526224005134	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
526224005135	heterodimer interface [polypeptide binding]; other site
526224005136	homodimer interface [polypeptide binding]; other site
526224005137	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
526224005138	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
526224005139	23S rRNA interface [nucleotide binding]; other site
526224005140	L7/L12 interface [polypeptide binding]; other site
526224005141	putative thiostrepton binding site; other site
526224005142	L25 interface [polypeptide binding]; other site
526224005143	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
526224005144	mRNA/rRNA interface [nucleotide binding]; other site
526224005145	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
526224005146	23S rRNA interface [nucleotide binding]; other site
526224005147	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
526224005148	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
526224005149	core dimer interface [polypeptide binding]; other site
526224005150	peripheral dimer interface [polypeptide binding]; other site
526224005151	L10 interface [polypeptide binding]; other site
526224005152	L11 interface [polypeptide binding]; other site
526224005153	putative EF-Tu interaction site [polypeptide binding]; other site
526224005154	putative EF-G interaction site [polypeptide binding]; other site
526224005155	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
526224005156	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
526224005157	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
526224005158	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
526224005159	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
526224005160	RPB10 interaction site [polypeptide binding]; other site
526224005161	RPB1 interaction site [polypeptide binding]; other site
526224005162	RPB11 interaction site [polypeptide binding]; other site
526224005163	RPB3 interaction site [polypeptide binding]; other site
526224005164	RPB12 interaction site [polypeptide binding]; other site
526224005165	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
526224005166	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
526224005167	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
526224005168	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
526224005169	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
526224005170	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
526224005171	cleft; other site
526224005172	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
526224005173	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
526224005174	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
526224005175	DNA binding site [nucleotide binding]
526224005176	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
526224005177	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
526224005178	gating phenylalanine in ion channel; other site
526224005179	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
526224005180	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
526224005181	DNA methylase; Region: N6_N4_Mtase; cl17433
526224005182	DNA methylase; Region: N6_N4_Mtase; pfam01555
526224005183	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
526224005184	histidinol dehydrogenase; Region: hisD; TIGR00069
526224005185	NAD binding site [chemical binding]; other site
526224005186	dimerization interface [polypeptide binding]; other site
526224005187	product binding site; other site
526224005188	substrate binding site [chemical binding]; other site
526224005189	zinc binding site [ion binding]; other site
526224005190	catalytic residues [active]
526224005191	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
526224005192	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
526224005193	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224005194	pantoate--beta-alanine ligase; Region: panC; TIGR00018
526224005195	active site
526224005196	nucleotide binding site [chemical binding]; other site
526224005197	HIGH motif; other site
526224005198	KMSKS motif; other site
526224005199	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
526224005200	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
526224005201	cofactor binding site; other site
526224005202	DNA binding site [nucleotide binding]
526224005203	substrate interaction site [chemical binding]; other site
526224005204	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224005205	Outer membrane efflux protein; Region: OEP; pfam02321
526224005206	Outer membrane efflux protein; Region: OEP; pfam02321
526224005207	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
526224005208	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
526224005209	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
526224005210	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
526224005211	anti sigma factor interaction site; other site
526224005212	regulatory phosphorylation site [posttranslational modification]; other site
526224005213	ATP synthase A chain; Region: ATP-synt_A; cl00413
526224005214	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
526224005215	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
526224005216	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
526224005217	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
526224005218	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
526224005219	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
526224005220	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
526224005221	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
526224005222	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
526224005223	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
526224005224	beta subunit interaction interface [polypeptide binding]; other site
526224005225	Walker A motif; other site
526224005226	ATP binding site [chemical binding]; other site
526224005227	Walker B motif; other site
526224005228	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
526224005229	Core-2/I-Branching enzyme; Region: Branch; pfam02485
526224005230	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
526224005231	core domain interface [polypeptide binding]; other site
526224005232	delta subunit interface [polypeptide binding]; other site
526224005233	epsilon subunit interface [polypeptide binding]; other site
526224005234	potential frameshift: common BLAST hit: gi|225621099|ref|YP_002722357.1|  ankyrin repeat-containing protein
526224005235	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005236	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005237	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224005238	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005239	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005240	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
526224005241	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
526224005242	active site
526224005243	Rubrerythrin [Energy production and conversion]; Region: COG1592
526224005244	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
526224005245	binuclear metal center [ion binding]; other site
526224005246	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
526224005247	iron binding site [ion binding]; other site
526224005248	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
526224005249	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
526224005250	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
526224005251	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
526224005252	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
526224005253	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
526224005254	RNA/DNA hybrid binding site [nucleotide binding]; other site
526224005255	active site
526224005256	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
526224005257	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
526224005258	HIRAN domain; Region: HIRAN; cl07418
526224005259	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
526224005260	Late competence development protein ComFB; Region: ComFB; pfam10719
526224005261	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
526224005262	metal binding site 2 [ion binding]; metal-binding site
526224005263	putative DNA binding helix; other site
526224005264	metal binding site 1 [ion binding]; metal-binding site
526224005265	dimer interface [polypeptide binding]; other site
526224005266	structural Zn2+ binding site [ion binding]; other site
526224005267	Uncharacterized conserved protein [Function unknown]; Region: COG1543
526224005268	N-terminal catalytic domain of  alpha-amylase ( AmyC ) and similar proteins; Region: GH57N_AmyC_like; cd10792
526224005269	active site
526224005270	substrate binding site [chemical binding]; other site
526224005271	catalytic site [active]
526224005272	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
526224005273	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005274	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005275	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005276	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
526224005277	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005278	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
526224005279	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005280	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
526224005281	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005282	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005283	Peptidase family M23; Region: Peptidase_M23; pfam01551
526224005284	Acylphosphatase; Region: Acylphosphatase; pfam00708
526224005285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224005286	S-adenosylmethionine binding site [chemical binding]; other site
526224005287	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
526224005288	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
526224005289	active site
526224005290	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224005291	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224005292	Walker A motif; other site
526224005293	ATP binding site [chemical binding]; other site
526224005294	Walker B motif; other site
526224005295	arginine finger; other site
526224005296	HAMP domain; Region: HAMP; pfam00672
526224005297	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224005298	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224005299	dimer interface [polypeptide binding]; other site
526224005300	putative CheW interface [polypeptide binding]; other site
526224005301	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224005302	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
526224005303	active site
526224005304	motif I; other site
526224005305	motif II; other site
526224005306	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224005307	trigger factor; Region: tig; TIGR00115
526224005308	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
526224005309	Clp protease; Region: CLP_protease; pfam00574
526224005310	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
526224005311	oligomer interface [polypeptide binding]; other site
526224005312	active site residues [active]
526224005313	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
526224005314	ClpX C4-type zinc finger; Region: zf-C4_ClpX; cl05964
526224005315	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224005316	Walker A motif; other site
526224005317	ATP binding site [chemical binding]; other site
526224005318	Walker B motif; other site
526224005319	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
526224005320	elongation factor P; Validated; Region: PRK00529
526224005321	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
526224005322	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
526224005323	RNA binding site [nucleotide binding]; other site
526224005324	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
526224005325	RNA binding site [nucleotide binding]; other site
526224005326	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224005327	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224005328	peptide binding site [polypeptide binding]; other site
526224005329	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224005330	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224005331	peptide binding site [polypeptide binding]; other site
526224005332	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
526224005333	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
526224005334	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
526224005335	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
526224005336	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
526224005337	active site
526224005338	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
526224005339	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
526224005340	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
526224005341	Rubredoxin; Region: Rubredoxin; pfam00301
526224005342	iron binding site [ion binding]; other site
526224005343	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
526224005344	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
526224005345	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224005346	peptide chain release factor 1; Validated; Region: prfA; PRK00591
526224005347	This domain is found in peptide chain release factors; Region: PCRF; smart00937
526224005348	RF-1 domain; Region: RF-1; pfam00472
526224005349	spiro-SPASM protein; Region: spiroSPASM; TIGR04321
526224005350	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
526224005351	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
526224005352	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
526224005353	active site
526224005354	Substrate binding site; other site
526224005355	Mg++ binding site; other site
526224005356	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
526224005357	DJ-1 family protein; Region: not_thiJ; TIGR01383
526224005358	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
526224005359	conserved cys residue [active]
526224005360	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224005361	TPR motif; other site
526224005362	TPR repeat; Region: TPR_11; pfam13414
526224005363	binding surface
526224005364	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
526224005365	active site
526224005366	intersubunit interface [polypeptide binding]; other site
526224005367	catalytic residue [active]
526224005368	Glucuronate isomerase; Region: UxaC; pfam02614
526224005369	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
526224005370	mannonate dehydratase; Provisional; Region: PRK03906
526224005371	mannonate dehydratase; Region: uxuA; TIGR00695
526224005372	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
526224005373	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
526224005374	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
526224005375	MFS/sugar transport protein; Region: MFS_2; pfam13347
526224005376	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
526224005377	beta-D-glucuronidase; Provisional; Region: PRK10150
526224005378	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
526224005379	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
526224005380	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
526224005381	Transcriptional regulators [Transcription]; Region: GntR; COG1802
526224005382	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
526224005383	DNA-binding site [nucleotide binding]; DNA binding site
526224005384	FCD domain; Region: FCD; pfam07729
526224005385	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
526224005386	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224005387	substrate binding site [chemical binding]; other site
526224005388	ATP binding site [chemical binding]; other site
526224005389	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
526224005390	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
526224005391	Predicted permeases [General function prediction only]; Region: COG0701
526224005392	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
526224005393	dimerization interface [polypeptide binding]; other site
526224005394	putative DNA binding site [nucleotide binding]; other site
526224005395	putative Zn2+ binding site [ion binding]; other site
526224005396	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
526224005397	active site
526224005398	catalytic residues [active]
526224005399	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224005400	S-adenosylmethionine binding site [chemical binding]; other site
526224005401	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
526224005402	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
526224005403	putative NAD(P) binding site [chemical binding]; other site
526224005404	putative substrate binding site [chemical binding]; other site
526224005405	catalytic Zn binding site [ion binding]; other site
526224005406	structural Zn binding site [ion binding]; other site
526224005407	dimer interface [polypeptide binding]; other site
526224005408	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224005409	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224005410	TPR motif; other site
526224005411	TPR repeat; Region: TPR_11; pfam13414
526224005412	binding surface
526224005413	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
526224005414	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
526224005415	HIGH motif; other site
526224005416	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
526224005417	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224005418	active site
526224005419	KMSKS motif; other site
526224005420	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
526224005421	tRNA binding surface [nucleotide binding]; other site
526224005422	AAA domain; Region: AAA_21; pfam13304
526224005423	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
526224005424	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
526224005425	catalytic residues [active]
526224005426	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
526224005427	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
526224005428	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
526224005429	active site
526224005430	TPR repeat; Region: TPR_11; pfam13414
526224005431	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
526224005432	ACT_3PGDH-like CD includes the C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-like; cd04879
526224005433	L-serine binding site [chemical binding]; other site
526224005434	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
526224005435	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
526224005436	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005437	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005438	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005439	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
526224005440	TrkA-N domain; Region: TrkA_N; pfam02254
526224005441	TrkA-C domain; Region: TrkA_C; pfam02080
526224005442	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
526224005443	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
526224005444	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
526224005445	active site
526224005446	substrate binding site [chemical binding]; other site
526224005447	metal binding site [ion binding]; metal-binding site
526224005448	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
526224005449	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224005450	ATP binding site [chemical binding]; other site
526224005451	putative Mg++ binding site [ion binding]; other site
526224005452	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224005453	nucleotide binding region [chemical binding]; other site
526224005454	ATP-binding site [chemical binding]; other site
526224005455	PilZ domain; Region: PilZ; pfam07238
526224005456	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
526224005457	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
526224005458	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
526224005459	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
526224005460	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005461	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005462	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005463	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005464	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005465	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005466	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005467	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005468	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005469	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
526224005470	Predicted transcriptional regulators [Transcription]; Region: COG1695
526224005471	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
526224005472	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
526224005473	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
526224005474	Walker A/P-loop; other site
526224005475	ATP binding site [chemical binding]; other site
526224005476	Q-loop/lid; other site
526224005477	ABC transporter signature motif; other site
526224005478	Walker B; other site
526224005479	D-loop; other site
526224005480	H-loop/switch region; other site
526224005481	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
526224005482	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
526224005483	FtsX-like permease family; Region: FtsX; pfam02687
526224005484	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224005485	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224005486	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
526224005487	ApbE family; Region: ApbE; pfam02424
526224005488	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
526224005489	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224005490	S-adenosylmethionine binding site [chemical binding]; other site
526224005491	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
526224005492	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
526224005493	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
526224005494	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
526224005495	homodimer interface [polypeptide binding]; other site
526224005496	substrate-cofactor binding pocket; other site
526224005497	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224005498	catalytic residue [active]
526224005499	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005500	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005501	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224005502	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
526224005503	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
526224005504	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
526224005505	Ligand binding site; other site
526224005506	metal-binding site
526224005507	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224005508	Radical SAM superfamily; Region: Radical_SAM; pfam04055
526224005509	FeS/SAM binding site; other site
526224005510	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224005511	active site
526224005512	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
526224005513	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
526224005514	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
526224005515	active site turn [active]
526224005516	phosphorylation site [posttranslational modification]
526224005517	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
526224005518	HPr interaction site; other site
526224005519	glycerol kinase (GK) interaction site [polypeptide binding]; other site
526224005520	active site
526224005521	phosphorylation site [posttranslational modification]
526224005522	Cache domain; Region: Cache_1; pfam02743
526224005523	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224005524	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224005525	dimer interface [polypeptide binding]; other site
526224005526	putative CheW interface [polypeptide binding]; other site
526224005527	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
526224005528	Protein of unknown function, DUF486; Region: DUF486; cl01236
526224005529	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
526224005530	Protein export membrane protein; Region: SecD_SecF; cl14618
526224005531	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
526224005532	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
526224005533	active site residue [active]
526224005534	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
526224005535	active site residue [active]
526224005536	Transcriptional regulators [Transcription]; Region: PurR; COG1609
526224005537	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
526224005538	DNA binding site [nucleotide binding]
526224005539	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
526224005540	dimerization interface [polypeptide binding]; other site
526224005541	ligand binding site [chemical binding]; other site
526224005542	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
526224005543	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
526224005544	ligand binding site [chemical binding]; other site
526224005545	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
526224005546	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
526224005547	Walker A/P-loop; other site
526224005548	ATP binding site [chemical binding]; other site
526224005549	Q-loop/lid; other site
526224005550	ABC transporter signature motif; other site
526224005551	Walker B; other site
526224005552	D-loop; other site
526224005553	H-loop/switch region; other site
526224005554	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
526224005555	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224005556	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
526224005557	TM-ABC transporter signature motif; other site
526224005558	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224005559	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
526224005560	TM-ABC transporter signature motif; other site
526224005561	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
526224005562	active site
526224005563	tetramer interface [polypeptide binding]; other site
526224005564	acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; Region: DapE-ArgE; TIGR01910
526224005565	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
526224005566	metal binding site [ion binding]; metal-binding site
526224005567	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
526224005568	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
526224005569	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224005570	substrate binding site [chemical binding]; other site
526224005571	dimer interface [polypeptide binding]; other site
526224005572	ATP binding site [chemical binding]; other site
526224005573	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224005574	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224005575	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
526224005576	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
526224005577	Potassium binding sites [ion binding]; other site
526224005578	Cesium cation binding sites [ion binding]; other site
526224005579	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
526224005580	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
526224005581	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
526224005582	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
526224005583	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
526224005584	substrate binding site [chemical binding]; other site
526224005585	active site
526224005586	catalytic residues [active]
526224005587	heterodimer interface [polypeptide binding]; other site
526224005588	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
526224005589	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
526224005590	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224005591	catalytic residue [active]
526224005592	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
526224005593	active site
526224005594	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
526224005595	active site
526224005596	ribulose/triose binding site [chemical binding]; other site
526224005597	phosphate binding site [ion binding]; other site
526224005598	substrate (anthranilate) binding pocket [chemical binding]; other site
526224005599	product (indole) binding pocket [chemical binding]; other site
526224005600	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
526224005601	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
526224005602	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
526224005603	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
526224005604	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
526224005605	glutamine binding [chemical binding]; other site
526224005606	catalytic triad [active]
526224005607	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
526224005608	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
526224005609	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
526224005610	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
526224005611	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
526224005612	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
526224005613	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224005614	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
526224005615	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224005616	DNA binding residues [nucleotide binding]
526224005617	DNA primase, catalytic core; Region: dnaG; TIGR01391
526224005618	CHC2 zinc finger; Region: zf-CHC2; cl17510
526224005619	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
526224005620	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
526224005621	active site
526224005622	metal binding site [ion binding]; metal-binding site
526224005623	interdomain interaction site; other site
526224005624	60S ribosomal protein L37a; Provisional; Region: PTZ00255; cl00875
526224005625	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
526224005626	nudix motif; other site
526224005627	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
526224005628	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
526224005629	Catalytic site [active]
526224005630	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
526224005631	AzlC protein; Region: AzlC; cl00570
526224005632	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
526224005633	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224005634	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224005635	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
526224005636	catalytic residues [active]
526224005637	dimer interface [polypeptide binding]; other site
526224005638	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
526224005639	dimer interface [polypeptide binding]; other site
526224005640	catalytic triad [active]
526224005641	peroxidatic and resolving cysteines [active]
526224005642	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
526224005643	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
526224005644	active site
526224005645	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
526224005646	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
526224005647	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224005648	active site
526224005649	phosphorylation site [posttranslational modification]
526224005650	intermolecular recognition site; other site
526224005651	dimerization interface [polypeptide binding]; other site
526224005652	DNA gyrase subunit A; Validated; Region: PRK05560
526224005653	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
526224005654	CAP-like domain; other site
526224005655	active site
526224005656	primary dimer interface [polypeptide binding]; other site
526224005657	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
526224005658	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
526224005659	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
526224005660	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
526224005661	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
526224005662	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
526224005663	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
526224005664	Walker A/P-loop; other site
526224005665	ATP binding site [chemical binding]; other site
526224005666	Q-loop/lid; other site
526224005667	ABC transporter signature motif; other site
526224005668	Walker B; other site
526224005669	D-loop; other site
526224005670	H-loop/switch region; other site
526224005671	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
526224005672	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
526224005673	N-acetylneuraminate lyase; Provisional; Region: PRK04147
526224005674	Class I aldolases; Region: Aldolase_Class_I; cl17187
526224005675	catalytic residue [active]
526224005676	Domain of unknown function (DUF386); Region: DUF386; cl01047
526224005677	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
526224005678	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
526224005679	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
526224005680	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
526224005681	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
526224005682	4Fe-4S binding domain; Region: Fer4; pfam00037
526224005683	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
526224005684	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
526224005685	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
526224005686	dimer interface [polypeptide binding]; other site
526224005687	[2Fe-2S] cluster binding site [ion binding]; other site
526224005688	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
526224005689	SLBB domain; Region: SLBB; pfam10531
526224005690	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
526224005691	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
526224005692	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
526224005693	putative dimer interface [polypeptide binding]; other site
526224005694	[2Fe-2S] cluster binding site [ion binding]; other site
526224005695	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
526224005696	Predicted ATPases [General function prediction only]; Region: COG1106
526224005697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005698	Walker A/P-loop; other site
526224005699	ATP binding site [chemical binding]; other site
526224005700	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
526224005701	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
526224005702	purine monophosphate binding site [chemical binding]; other site
526224005703	dimer interface [polypeptide binding]; other site
526224005704	putative catalytic residues [active]
526224005705	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
526224005706	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
526224005707	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224005708	active site residue [active]
526224005709	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
526224005710	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224005711	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224005712	peptide binding site [polypeptide binding]; other site
526224005713	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
526224005714	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
526224005715	catalytic triad [active]
526224005716	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
526224005717	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
526224005718	catalytic triad [active]
526224005719	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
526224005720	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
526224005721	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
526224005722	metal ion-dependent adhesion site (MIDAS); other site
526224005723	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
526224005724	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224005725	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
526224005726	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
526224005727	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
526224005728	dimerization interface [polypeptide binding]; other site
526224005729	ATP binding site [chemical binding]; other site
526224005730	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
526224005731	dimerization interface [polypeptide binding]; other site
526224005732	ATP binding site [chemical binding]; other site
526224005733	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
526224005734	putative active site [active]
526224005735	catalytic triad [active]
526224005736	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
526224005737	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
526224005738	putative metal binding site [ion binding]; other site
526224005739	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
526224005740	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
526224005741	active site
526224005742	Uncharacterized conserved protein [Function unknown]; Region: COG1624
526224005743	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
526224005744	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
526224005745	YbbR-like protein; Region: YbbR; pfam07949
526224005746	N-Utilization Substance G (NusG) N terminal (NGN) insert and Lin0431 are part of DUF1312; Region: DUF1312; cl02206
526224005747	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
526224005748	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
526224005749	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224005750	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005751	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005752	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
526224005753	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
526224005754	active pocket/dimerization site; other site
526224005755	active site
526224005756	phosphorylation site [posttranslational modification]
526224005757	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
526224005758	dimerization domain swap beta strand [polypeptide binding]; other site
526224005759	regulatory protein interface [polypeptide binding]; other site
526224005760	active site
526224005761	regulatory phosphorylation site [posttranslational modification]; other site
526224005762	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
526224005763	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
526224005764	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
526224005765	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
526224005766	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
526224005767	HEAT repeats; Region: HEAT_2; pfam13646
526224005768	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
526224005769	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005770	Walker A/P-loop; other site
526224005771	ATP binding site [chemical binding]; other site
526224005772	Q-loop/lid; other site
526224005773	ABC transporter signature motif; other site
526224005774	Walker B; other site
526224005775	D-loop; other site
526224005776	H-loop/switch region; other site
526224005777	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
526224005778	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005779	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005780	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224005781	ferrochelatase; Reviewed; Region: hemH; PRK00035
526224005782	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
526224005783	C-terminal domain interface [polypeptide binding]; other site
526224005784	active site
526224005785	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
526224005786	active site
526224005787	N-terminal domain interface [polypeptide binding]; other site
526224005788	Bacterial Ig-like domain; Region: Big_5; pfam13205
526224005789	Bacterial Ig-like domain; Region: Big_5; pfam13205
526224005790	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
526224005791	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
526224005792	MG2 domain; Region: A2M_N; pfam01835
526224005793	Alpha-2-macroglobulin family; Region: A2M; pfam00207
526224005794	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
526224005795	surface patch; other site
526224005796	thioester region; other site
526224005797	specificity defining residues; other site
526224005798	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224005799	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005800	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224005801	META domain; Region: META; pfam03724
526224005802	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224005803	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
526224005804	active site
526224005805	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
526224005806	active site
526224005807	Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786
526224005808	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
526224005809	putative active site [active]
526224005810	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK08527
526224005811	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
526224005812	PYR/PP interface [polypeptide binding]; other site
526224005813	dimer interface [polypeptide binding]; other site
526224005814	TPP binding site [chemical binding]; other site
526224005815	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
526224005816	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
526224005817	TPP-binding site [chemical binding]; other site
526224005818	dimer interface [polypeptide binding]; other site
526224005819	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
526224005820	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
526224005821	putative valine binding site [chemical binding]; other site
526224005822	dimer interface [polypeptide binding]; other site
526224005823	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
526224005824	ketol-acid reductoisomerase; Provisional; Region: PRK05479
526224005825	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
526224005826	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
526224005827	2-isopropylmalate synthase; Validated; Region: PRK00915
526224005828	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
526224005829	active site
526224005830	catalytic residues [active]
526224005831	metal binding site [ion binding]; metal-binding site
526224005832	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
526224005833	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
526224005834	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
526224005835	substrate binding site [chemical binding]; other site
526224005836	ligand binding site [chemical binding]; other site
526224005837	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
526224005838	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
526224005839	substrate binding site [chemical binding]; other site
526224005840	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
526224005841	tartrate dehydrogenase; Region: TTC; TIGR02089
526224005842	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
526224005843	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
526224005844	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
526224005845	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
526224005846	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
526224005847	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
526224005848	active site
526224005849	dimerization interface [polypeptide binding]; other site
526224005850	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
526224005851	Carbon starvation protein CstA; Region: CstA; pfam02554
526224005852	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
526224005853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224005854	TPR motif; other site
526224005855	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224005856	binding surface
526224005857	Cupin domain; Region: Cupin_2; pfam07883
526224005858	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
526224005859	MutS domain I; Region: MutS_I; pfam01624
526224005860	MutS domain II; Region: MutS_II; pfam05188
526224005861	MutS domain III; Region: MutS_III; pfam05192
526224005862	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
526224005863	Walker A/P-loop; other site
526224005864	ATP binding site [chemical binding]; other site
526224005865	Q-loop/lid; other site
526224005866	ABC transporter signature motif; other site
526224005867	Walker B; other site
526224005868	D-loop; other site
526224005869	H-loop/switch region; other site
526224005870	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224005871	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224005872	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224005873	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224005874	peptide binding site [polypeptide binding]; other site
526224005875	CTP synthetase; Validated; Region: pyrG; PRK05380
526224005876	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
526224005877	Catalytic site [active]
526224005878	active site
526224005879	UTP binding site [chemical binding]; other site
526224005880	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
526224005881	active site
526224005882	putative oxyanion hole; other site
526224005883	catalytic triad [active]
526224005884	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
526224005885	trimer interface [polypeptide binding]; other site
526224005886	active site
526224005887	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
526224005888	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
526224005889	active site
526224005890	dimer interface [polypeptide binding]; other site
526224005891	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
526224005892	dimer interface [polypeptide binding]; other site
526224005893	active site
526224005894	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
526224005895	N-terminal catalytic domain of 4-alpha-glucanotransferase; glycoside hydrolase family 57 (GH57); Region: GH57N_TLGT_like; cd10793
526224005896	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
526224005897	active site
526224005898	catalytic site [active]
526224005899	homodimer interface [polypeptide binding]; other site
526224005900	Lid 1; other site
526224005901	Domain of unknown function (DUF1925); Region: DUF1925; pfam09094
526224005902	Domain of unknown function (DUF1926); Region: DUF1926; pfam09095
526224005903	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
526224005904	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
526224005905	glutaminase active site [active]
526224005906	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
526224005907	dimer interface [polypeptide binding]; other site
526224005908	active site
526224005909	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
526224005910	dimer interface [polypeptide binding]; other site
526224005911	active site
526224005912	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
526224005913	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
526224005914	active site
526224005915	DNA binding site [nucleotide binding]
526224005916	Int/Topo IB signature motif; other site
526224005917	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
526224005918	active site
526224005919	catalytic site [active]
526224005920	substrate binding site [chemical binding]; other site
526224005921	Predicted chitinase [General function prediction only]; Region: COG3179
526224005922	catalytic residue [active]
526224005923	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
526224005924	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
526224005925	DNA binding residues [nucleotide binding]
526224005926	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
526224005927	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
526224005928	oligomerization interface [polypeptide binding]; other site
526224005929	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
526224005930	Phage capsid family; Region: Phage_capsid; pfam05065
526224005931	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
526224005932	Phage portal protein; Region: Phage_portal; pfam04860
526224005933	Phage-related protein [Function unknown]; Region: COG4695
526224005934	Phage terminase, small subunit; Region: Terminase_4; cl01525
526224005935	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
526224005936	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
526224005937	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
526224005938	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
526224005939	active site
526224005940	catalytic residues [active]
526224005941	DNA binding site [nucleotide binding]
526224005942	Int/Topo IB signature motif; other site
526224005943	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
526224005944	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
526224005945	dimer interface [polypeptide binding]; other site
526224005946	ssDNA binding site [nucleotide binding]; other site
526224005947	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224005948	ribonuclease Y; Region: RNase_Y; TIGR03319
526224005949	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
526224005950	active site
526224005951	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
526224005952	Walker A motif; other site
526224005953	ATP binding site [chemical binding]; other site
526224005954	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
526224005955	Part of AAA domain; Region: AAA_19; pfam13245
526224005956	Family description; Region: UvrD_C_2; pfam13538
526224005957	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
526224005958	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005959	Walker A/P-loop; other site
526224005960	ATP binding site [chemical binding]; other site
526224005961	Q-loop/lid; other site
526224005962	ABC transporter signature motif; other site
526224005963	Walker B; other site
526224005964	D-loop; other site
526224005965	H-loop/switch region; other site
526224005966	TOBE domain; Region: TOBE_2; pfam08402
526224005967	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224005968	dimer interface [polypeptide binding]; other site
526224005969	conserved gate region; other site
526224005970	putative PBP binding loops; other site
526224005971	ABC-ATPase subunit interface; other site
526224005972	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
526224005973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224005974	dimer interface [polypeptide binding]; other site
526224005975	conserved gate region; other site
526224005976	putative PBP binding loops; other site
526224005977	ABC-ATPase subunit interface; other site
526224005978	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
526224005979	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
526224005980	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
526224005981	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
526224005982	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
526224005983	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
526224005984	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005985	Walker A/P-loop; other site
526224005986	ATP binding site [chemical binding]; other site
526224005987	Q-loop/lid; other site
526224005988	ABC transporter signature motif; other site
526224005989	Walker B; other site
526224005990	D-loop; other site
526224005991	H-loop/switch region; other site
526224005992	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
526224005993	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
526224005994	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224005995	Walker A/P-loop; other site
526224005996	ATP binding site [chemical binding]; other site
526224005997	Q-loop/lid; other site
526224005998	ABC transporter signature motif; other site
526224005999	Walker B; other site
526224006000	D-loop; other site
526224006001	H-loop/switch region; other site
526224006002	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
526224006003	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
526224006004	active site
526224006005	putative substrate binding pocket [chemical binding]; other site
526224006006	Protein of unknown function (DUF454); Region: DUF454; cl01063
526224006007	Nitrous oxide-stimulated promoter; Region: YgbA_NO; cl08119
526224006008	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224006009	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
526224006010	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
526224006011	dimer interface [polypeptide binding]; other site
526224006012	active site
526224006013	glycine-pyridoxal phosphate binding site [chemical binding]; other site
526224006014	folate binding site [chemical binding]; other site
526224006015	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
526224006016	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
526224006017	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
526224006018	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
526224006019	active site
526224006020	trimer interface [polypeptide binding]; other site
526224006021	allosteric site; other site
526224006022	active site lid [active]
526224006023	hexamer (dimer of trimers) interface [polypeptide binding]; other site
526224006024	phosphopentomutase; Provisional; Region: PRK05362
526224006025	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
526224006026	GMP synthase; Reviewed; Region: guaA; PRK00074
526224006027	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
526224006028	AMP/PPi binding site [chemical binding]; other site
526224006029	candidate oxyanion hole; other site
526224006030	catalytic triad [active]
526224006031	potential glutamine specificity residues [chemical binding]; other site
526224006032	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
526224006033	ATP Binding subdomain [chemical binding]; other site
526224006034	Ligand Binding sites [chemical binding]; other site
526224006035	Dimerization subdomain; other site
526224006036	GTP-binding protein; Provisional; Region: PTZ00258
526224006037	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
526224006038	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
526224006039	active site
526224006040	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006041	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006042	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006043	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006044	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
526224006045	active site
526224006046	substrate binding site [chemical binding]; other site
526224006047	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
526224006048	FMN binding site [chemical binding]; other site
526224006049	putative catalytic residues [active]
526224006050	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006051	TPR motif; other site
526224006052	TPR repeat; Region: TPR_11; pfam13414
526224006053	binding surface
526224006054	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006055	binding surface
526224006056	TPR motif; other site
526224006057	TPR repeat; Region: TPR_11; pfam13414
526224006058	TPR repeat; Region: TPR_11; pfam13414
526224006059	TPR repeat; Region: TPR_11; pfam13414
526224006060	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006061	binding surface
526224006062	TPR motif; other site
526224006063	TPR repeat; Region: TPR_11; pfam13414
526224006064	TPR repeat; Region: TPR_11; pfam13414
526224006065	Tetratricopeptide repeat; Region: TPR_1; pfam00515
526224006066	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006067	binding surface
526224006068	TPR motif; other site
526224006069	TPR repeat; Region: TPR_11; pfam13414
526224006070	TPR repeat; Region: TPR_11; pfam13414
526224006071	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006072	binding surface
526224006073	TPR motif; other site
526224006074	TPR repeat; Region: TPR_11; pfam13414
526224006075	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006076	binding surface
526224006077	TPR motif; other site
526224006078	TPR repeat; Region: TPR_11; pfam13414
526224006079	TPR repeat; Region: TPR_11; pfam13414
526224006080	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006081	binding surface
526224006082	TPR motif; other site
526224006083	TPR repeat; Region: TPR_11; pfam13414
526224006084	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006085	binding surface
526224006086	TPR motif; other site
526224006087	TPR repeat; Region: TPR_11; pfam13414
526224006088	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006089	TPR repeat; Region: TPR_11; pfam13414
526224006090	binding surface
526224006091	TPR motif; other site
526224006092	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006093	binding surface
526224006094	TPR repeat; Region: TPR_11; pfam13414
526224006095	TPR motif; other site
526224006096	TPR repeat; Region: TPR_11; pfam13414
526224006097	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006098	binding surface
526224006099	TPR motif; other site
526224006100	TPR repeat; Region: TPR_11; pfam13414
526224006101	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006102	binding surface
526224006103	TPR motif; other site
526224006104	TPR repeat; Region: TPR_11; pfam13414
526224006105	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006106	binding surface
526224006107	TPR repeat; Region: TPR_11; pfam13414
526224006108	TPR motif; other site
526224006109	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006110	binding surface
526224006111	TPR motif; other site
526224006112	TPR repeat; Region: TPR_11; pfam13414
526224006113	TPR repeat; Region: TPR_11; pfam13414
526224006114	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006115	binding surface
526224006116	TPR motif; other site
526224006117	TPR repeat; Region: TPR_11; pfam13414
526224006118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006119	binding surface
526224006120	TPR motif; other site
526224006121	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
526224006122	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224006123	TM-ABC transporter signature motif; other site
526224006124	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
526224006125	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
526224006126	Walker A/P-loop; other site
526224006127	ATP binding site [chemical binding]; other site
526224006128	Q-loop/lid; other site
526224006129	ABC transporter signature motif; other site
526224006130	Walker B; other site
526224006131	D-loop; other site
526224006132	H-loop/switch region; other site
526224006133	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
526224006134	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
526224006135	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
526224006136	ligand binding site [chemical binding]; other site
526224006137	calcium binding site [ion binding]; other site
526224006138	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
526224006139	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
526224006140	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
526224006141	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
526224006142	ligand binding site [chemical binding]; other site
526224006143	calcium binding site [ion binding]; other site
526224006144	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
526224006145	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
526224006146	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
526224006147	active site
526224006148	dimer interface [polypeptide binding]; other site
526224006149	metal binding site [ion binding]; metal-binding site
526224006150	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224006151	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
526224006152	heat shock protein 90; Provisional; Region: PRK05218
526224006153	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224006154	ATP binding site [chemical binding]; other site
526224006155	Mg2+ binding site [ion binding]; other site
526224006156	G-X-G motif; other site
526224006157	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
526224006158	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
526224006159	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
526224006160	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
526224006161	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
526224006162	DNA binding residues [nucleotide binding]
526224006163	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
526224006164	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
526224006165	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
526224006166	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
526224006167	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
526224006168	N-acetyl-D-glucosamine binding site [chemical binding]; other site
526224006169	catalytic residue [active]
526224006170	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12816
526224006171	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
526224006172	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
526224006173	AAA domain; Region: AAA_21; pfam13304
526224006174	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
526224006175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224006176	dimer interface [polypeptide binding]; other site
526224006177	conserved gate region; other site
526224006178	putative PBP binding loops; other site
526224006179	ABC-ATPase subunit interface; other site
526224006180	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
526224006181	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
526224006182	Walker A/P-loop; other site
526224006183	ATP binding site [chemical binding]; other site
526224006184	Q-loop/lid; other site
526224006185	ABC transporter signature motif; other site
526224006186	Walker B; other site
526224006187	D-loop; other site
526224006188	H-loop/switch region; other site
526224006189	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224006190	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224006191	substrate binding pocket [chemical binding]; other site
526224006192	membrane-bound complex binding site; other site
526224006193	hinge residues; other site
526224006194	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
526224006195	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224006196	substrate binding pocket [chemical binding]; other site
526224006197	membrane-bound complex binding site; other site
526224006198	hinge residues; other site
526224006199	Leucine rich repeat; Region: LRR_8; pfam13855
526224006200	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
526224006201	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
526224006202	active site
526224006203	catalytic residue [active]
526224006204	dimer interface [polypeptide binding]; other site
526224006205	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
526224006206	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
526224006207	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
526224006208	shikimate binding site; other site
526224006209	NAD(P) binding site [chemical binding]; other site
526224006210	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
526224006211	homotrimer interaction site [polypeptide binding]; other site
526224006212	putative active site [active]
526224006213	Domain of unknown function (DUF368); Region: DUF368; pfam04018
526224006214	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
526224006215	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224006216	binding surface
526224006217	TPR motif; other site
526224006218	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
526224006219	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006220	TPR motif; other site
526224006221	binding surface
526224006222	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
526224006223	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
526224006224	6-phosphofructokinase; Provisional; Region: PRK03202
526224006225	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
526224006226	active site
526224006227	ADP/pyrophosphate binding site [chemical binding]; other site
526224006228	dimerization interface [polypeptide binding]; other site
526224006229	allosteric effector site; other site
526224006230	fructose-1,6-bisphosphate binding site; other site
526224006231	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
526224006232	MgtE intracellular N domain; Region: MgtE_N; smart00924
526224006233	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
526224006234	Divalent cation transporter; Region: MgtE; pfam01769
526224006235	Uncharacterized conserved protein [Function unknown]; Region: COG2006
526224006236	Domain of unknown function (DUF362); Region: DUF362; pfam04015
526224006237	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
526224006238	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
526224006239	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
526224006240	Cl- selectivity filter; other site
526224006241	Cl- binding residues [ion binding]; other site
526224006242	pore gating glutamate residue; other site
526224006243	dimer interface [polypeptide binding]; other site
526224006244	H+/Cl- coupling transport residue; other site
526224006245	GTP-binding protein YchF; Reviewed; Region: PRK09601
526224006246	YchF GTPase; Region: YchF; cd01900
526224006247	G1 box; other site
526224006248	GTP/Mg2+ binding site [chemical binding]; other site
526224006249	Switch I region; other site
526224006250	G2 box; other site
526224006251	Switch II region; other site
526224006252	G3 box; other site
526224006253	G4 box; other site
526224006254	G5 box; other site
526224006255	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
526224006256	UDP-N-acetylmuramate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: MurB; COG0812
526224006257	FAD binding domain; Region: FAD_binding_4; pfam01565
526224006258	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
526224006259	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
526224006260	active site 2 [active]
526224006261	active site 1 [active]
526224006262	TPR repeat; Region: TPR_11; pfam13414
526224006263	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006264	binding surface
526224006265	TPR motif; other site
526224006266	TPR repeat; Region: TPR_11; pfam13414
526224006267	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006268	TPR motif; other site
526224006269	TPR repeat; Region: TPR_11; pfam13414
526224006270	binding surface
526224006271	TPR repeat; Region: TPR_11; pfam13414
526224006272	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006273	binding surface
526224006274	TPR motif; other site
526224006275	TPR repeat; Region: TPR_11; pfam13414
526224006276	TPR repeat; Region: TPR_11; pfam13414
526224006277	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006278	binding surface
526224006279	TPR motif; other site
526224006280	TPR repeat; Region: TPR_11; pfam13414
526224006281	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
526224006282	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006283	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006284	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006285	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006286	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006287	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006288	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006289	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006290	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
526224006291	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
526224006292	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
526224006293	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
526224006294	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
526224006295	dimer interface [polypeptide binding]; other site
526224006296	ssDNA binding site [nucleotide binding]; other site
526224006297	tetramer (dimer of dimers) interface [polypeptide binding]; other site
526224006298	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
526224006299	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224006300	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224006301	active site
526224006302	catalytic tetrad [active]
526224006303	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
526224006304	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
526224006305	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
526224006306	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
526224006307	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
526224006308	catalytic residues [active]
526224006309	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006310	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006311	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224006312	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224006313	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
526224006314	Transcriptional regulator [Transcription]; Region: LytR; COG1316
526224006315	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
526224006316	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
526224006317	threonine synthase; Validated; Region: PRK08329
526224006318	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
526224006319	TM2 domain; Region: TM2; pfam05154
526224006320	recombinase A; Provisional; Region: recA; PRK09354
526224006321	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
526224006322	hexamer interface [polypeptide binding]; other site
526224006323	Walker A motif; other site
526224006324	ATP binding site [chemical binding]; other site
526224006325	Walker B motif; other site
526224006326	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224006327	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
526224006328	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
526224006329	FAD binding pocket [chemical binding]; other site
526224006330	FAD binding motif [chemical binding]; other site
526224006331	phosphate binding motif [ion binding]; other site
526224006332	beta-alpha-beta structure motif; other site
526224006333	NAD binding pocket [chemical binding]; other site
526224006334	Iron coordination center [ion binding]; other site
526224006335	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
526224006336	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
526224006337	heterodimer interface [polypeptide binding]; other site
526224006338	active site
526224006339	FMN binding site [chemical binding]; other site
526224006340	homodimer interface [polypeptide binding]; other site
526224006341	substrate binding site [chemical binding]; other site
526224006342	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
526224006343	active site
526224006344	dimer interface [polypeptide binding]; other site
526224006345	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
526224006346	active site
526224006347	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224006348	active site residue [active]
526224006349	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
526224006350	putative homotetramer interface [polypeptide binding]; other site
526224006351	putative homodimer interface [polypeptide binding]; other site
526224006352	putative allosteric switch controlling residues; other site
526224006353	putative metal binding site [ion binding]; other site
526224006354	putative homodimer-homodimer interface [polypeptide binding]; other site
526224006355	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
526224006356	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224006357	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224006358	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
526224006359	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
526224006360	active site residue [active]
526224006361	Putative motility protein; Region: YjfB_motility; pfam14070
526224006362	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
526224006363	non-specific DNA binding site [nucleotide binding]; other site
526224006364	salt bridge; other site
526224006365	sequence-specific DNA binding site [nucleotide binding]; other site
526224006366	potential frameshift: common BLAST hit: gi|225619538|ref|YP_002720795.1| ankyrin repeat-containing protein
526224006367	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006368	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006369	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006370	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006371	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006372	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224006373	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224006374	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
526224006375	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
526224006376	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
526224006377	putative active site [active]
526224006378	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
526224006379	Domain of unknown function DUF20; Region: UPF0118; pfam01594
526224006380	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
526224006381	Part of AAA domain; Region: AAA_19; pfam13245
526224006382	Family description; Region: UvrD_C_2; pfam13538
526224006383	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
526224006384	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006385	TPR motif; other site
526224006386	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
526224006387	DNA protecting protein DprA; Region: dprA; TIGR00732
526224006388	DNA topoisomerase I; Validated; Region: PRK05582
526224006389	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
526224006390	active site
526224006391	interdomain interaction site; other site
526224006392	putative metal-binding site [ion binding]; other site
526224006393	nucleotide binding site [chemical binding]; other site
526224006394	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
526224006395	domain I; other site
526224006396	DNA binding groove [nucleotide binding]
526224006397	phosphate binding site [ion binding]; other site
526224006398	domain II; other site
526224006399	domain III; other site
526224006400	nucleotide binding site [chemical binding]; other site
526224006401	catalytic site [active]
526224006402	domain IV; other site
526224006403	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
526224006404	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
526224006405	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
526224006406	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
526224006407	active site
526224006408	metal binding site [ion binding]; metal-binding site
526224006409	AAA domain; Region: AAA_23; pfam13476
526224006410	AAA domain; Region: AAA_21; pfam13304
526224006411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224006412	Walker B; other site
526224006413	D-loop; other site
526224006414	H-loop/switch region; other site
526224006415	Protein of unknown function (DUF563); Region: DUF563; pfam04577
526224006416	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
526224006417	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
526224006418	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
526224006419	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224006420	dimer interface [polypeptide binding]; other site
526224006421	putative CheW interface [polypeptide binding]; other site
526224006422	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224006423	dimer interface [polypeptide binding]; other site
526224006424	putative CheW interface [polypeptide binding]; other site
526224006425	Colicin V production protein; Region: Colicin_V; pfam02674
526224006426	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
526224006427	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
526224006428	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
526224006429	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224006430	catalytic residue [active]
526224006431	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
526224006432	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
526224006433	CPxP  motif; other site
526224006434	DsrE/DsrF-like family; Region: DrsE; pfam02635
526224006435	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
526224006436	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
526224006437	ABC-ATPase subunit  interface; other site
526224006438	dimer interface [polypeptide binding]; other site
526224006439	putative PBP binding regions; other site
526224006440	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224006441	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
526224006442	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
526224006443	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
526224006444	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
526224006445	intersubunit interface [polypeptide binding]; other site
526224006446	META domain; Region: META; pfam03724
526224006447	META domain; Region: META; pfam03724
526224006448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224006449	dimer interface [polypeptide binding]; other site
526224006450	conserved gate region; other site
526224006451	putative PBP binding loops; other site
526224006452	ABC-ATPase subunit interface; other site
526224006453	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
526224006454	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224006455	Walker A/P-loop; other site
526224006456	ATP binding site [chemical binding]; other site
526224006457	Q-loop/lid; other site
526224006458	ABC transporter signature motif; other site
526224006459	Walker B; other site
526224006460	D-loop; other site
526224006461	H-loop/switch region; other site
526224006462	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
526224006463	Tetratricopeptide repeat; Region: TPR_12; pfam13424
526224006464	TPR repeat; Region: TPR_11; pfam13414
526224006465	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006466	binding surface
526224006467	TPR motif; other site
526224006468	TPR repeat; Region: TPR_11; pfam13414
526224006469	TPR repeat; Region: TPR_11; pfam13414
526224006470	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006471	binding surface
526224006472	TPR motif; other site
526224006473	TPR repeat; Region: TPR_11; pfam13414
526224006474	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006475	binding surface
526224006476	TPR repeat; Region: TPR_11; pfam13414
526224006477	TPR motif; other site
526224006478	TPR repeat; Region: TPR_11; pfam13414
526224006479	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006480	binding surface
526224006481	TPR motif; other site
526224006482	TPR repeat; Region: TPR_11; pfam13414
526224006483	TPR repeat; Region: TPR_11; pfam13414
526224006484	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006485	TPR motif; other site
526224006486	binding surface
526224006487	TPR repeat; Region: TPR_11; pfam13414
526224006488	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006489	binding surface
526224006490	TPR motif; other site
526224006491	TPR repeat; Region: TPR_11; pfam13414
526224006492	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224006493	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224006494	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224006495	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
526224006496	Uncharacterized conserved protein [Function unknown]; Region: COG1479
526224006497	Protein of unknown function DUF262; Region: DUF262; pfam03235
526224006498	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
526224006499	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
526224006500	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
526224006501	cell division protein FtsZ; Region: ftsZ; TIGR00065
526224006502	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
526224006503	nucleotide binding site [chemical binding]; other site
526224006504	SulA interaction site; other site
526224006505	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006506	binding surface
526224006507	TPR motif; other site
526224006508	Type II intron maturase; Region: Intron_maturas2; pfam01348
526224006509	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
526224006510	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
526224006511	CoA-binding site [chemical binding]; other site
526224006512	ATP-binding [chemical binding]; other site
526224006513	Sporulation related domain; Region: SPOR; pfam05036
526224006514	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
526224006515	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
526224006516	Ligand Binding Site [chemical binding]; other site
526224006517	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
526224006518	4Fe-4S binding domain; Region: Fer4; pfam00037
526224006519	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
526224006520	von Willebrand factor type A domain; Region: VWA_2; pfam13519
526224006521	metal ion-dependent adhesion site (MIDAS); other site
526224006522	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224006523	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224006524	TPR motif; other site
526224006525	binding surface
526224006526	Oxygen tolerance; Region: BatD; pfam13584
526224006527	TPR repeat; Region: TPR_11; pfam13414
526224006528	Bacterial SH3 domain; Region: SH3_4; pfam06347
526224006529	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
526224006530	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
526224006531	Ligand Binding Site [chemical binding]; other site
526224006532	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
526224006533	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
526224006534	Predicted transcriptional regulator [Transcription]; Region: COG1959
526224006535	Transcriptional regulator; Region: Rrf2; pfam02082
526224006536	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224006537	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224006538	ligand binding site [chemical binding]; other site
526224006539	helix_turn_helix, cAMP Regulatory protein; Region: HTH_CRP; smart00419
526224006540	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
526224006541	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
526224006542	Na binding site [ion binding]; other site
526224006543	cyclically-permuted mutarotase family protein; Region: mutarot_permut; TIGR03548
526224006544	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
526224006545	regulatory protein interface [polypeptide binding]; other site
526224006546	regulatory phosphorylation site [posttranslational modification]; other site
526224006547	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
526224006548	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
526224006549	active site
526224006550	metal binding site [ion binding]; metal-binding site
526224006551	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
526224006552	putative active site [active]
526224006553	NodB motif; other site
526224006554	diaminopimelate decarboxylase; Region: lysA; TIGR01048
526224006555	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
526224006556	active site
526224006557	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
526224006558	substrate binding site [chemical binding]; other site
526224006559	catalytic residues [active]
526224006560	dimer interface [polypeptide binding]; other site
526224006561	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
526224006562	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
526224006563	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
526224006564	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
526224006565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224006566	active site
526224006567	phosphorylation site [posttranslational modification]
526224006568	intermolecular recognition site; other site
526224006569	dimerization interface [polypeptide binding]; other site
526224006570	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
526224006571	DNA binding site [nucleotide binding]
526224006572	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
526224006573	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
526224006574	dimer interface [polypeptide binding]; other site
526224006575	phosphorylation site [posttranslational modification]
526224006576	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224006577	ATP binding site [chemical binding]; other site
526224006578	Mg2+ binding site [ion binding]; other site
526224006579	G-X-G motif; other site
526224006580	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
526224006581	metal-binding site [ion binding]
526224006582	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
526224006583	RuvA N terminal domain; Region: RuvA_N; pfam01330
526224006584	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
526224006585	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
526224006586	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
526224006587	Coenzyme A binding pocket [chemical binding]; other site
526224006588	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
526224006589	active site
526224006590	substrate-binding site [chemical binding]; other site
526224006591	metal-binding site [ion binding]
526224006592	GTP binding site [chemical binding]; other site
526224006593	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006594	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006595	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224006596	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006597	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224006598	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224006599	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
526224006600	intersubunit interface [polypeptide binding]; other site
526224006601	active site
526224006602	Zn2+ binding site [ion binding]; other site
526224006603	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
526224006604	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
526224006605	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
526224006606	catalytic site [active]
526224006607	subunit interface [polypeptide binding]; other site
526224006608	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
526224006609	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
526224006610	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
526224006611	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
526224006612	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
526224006613	ATP-grasp domain; Region: ATP-grasp_4; cl17255
526224006614	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
526224006615	IMP binding site; other site
526224006616	dimer interface [polypeptide binding]; other site
526224006617	interdomain contacts; other site
526224006618	partial ornithine binding site; other site
526224006619	GTPase CgtA; Reviewed; Region: obgE; PRK12299
526224006620	GTP1/OBG; Region: GTP1_OBG; pfam01018
526224006621	Obg GTPase; Region: Obg; cd01898
526224006622	G1 box; other site
526224006623	GTP/Mg2+ binding site [chemical binding]; other site
526224006624	Switch I region; other site
526224006625	G2 box; other site
526224006626	G3 box; other site
526224006627	Switch II region; other site
526224006628	G4 box; other site
526224006629	G5 box; other site
526224006630	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
526224006631	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224006632	FeS/SAM binding site; other site
526224006633	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
526224006634	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
526224006635	RbsD / FucU transport protein family; Region: RbsD_FucU; cl00809
526224006636	L-fucose isomerase; Provisional; Region: fucI; PRK10991
526224006637	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
526224006638	hexamer (dimer of trimers) interface [polypeptide binding]; other site
526224006639	trimer interface [polypeptide binding]; other site
526224006640	substrate binding site [chemical binding]; other site
526224006641	Mn binding site [ion binding]; other site
526224006642	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
526224006643	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
526224006644	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224006645	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
526224006646	TM-ABC transporter signature motif; other site
526224006647	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
526224006648	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
526224006649	Walker A/P-loop; other site
526224006650	ATP binding site [chemical binding]; other site
526224006651	Q-loop/lid; other site
526224006652	ABC transporter signature motif; other site
526224006653	Walker B; other site
526224006654	D-loop; other site
526224006655	H-loop/switch region; other site
526224006656	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
526224006657	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
526224006658	N- and C-terminal domain interface [polypeptide binding]; other site
526224006659	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
526224006660	active site
526224006661	putative catalytic site [active]
526224006662	metal binding site [ion binding]; metal-binding site
526224006663	ATP binding site [chemical binding]; other site
526224006664	carbohydrate binding site [chemical binding]; other site
526224006665	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
526224006666	intersubunit interface [polypeptide binding]; other site
526224006667	active site
526224006668	Zn2+ binding site [ion binding]; other site
526224006669	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
526224006670	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
526224006671	dimer interface [polypeptide binding]; other site
526224006672	active site
526224006673	metal binding site [ion binding]; metal-binding site
526224006674	putative hydrolase; Provisional; Region: PRK02113
526224006675	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
526224006676	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
526224006677	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
526224006678	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
526224006679	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
526224006680	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224006681	active site
526224006682	phosphorylation site [posttranslational modification]
526224006683	intermolecular recognition site; other site
526224006684	dimerization interface [polypeptide binding]; other site
526224006685	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
526224006686	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
526224006687	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
526224006688	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
526224006689	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
526224006690	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
526224006691	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
526224006692	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
526224006693	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
526224006694	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224006695	short chain dehydrogenase; Provisional; Region: PRK06940
526224006696	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
526224006697	NAD(P) binding site [chemical binding]; other site
526224006698	active site
526224006699	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224006700	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
526224006701	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
526224006702	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
526224006703	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224006704	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224006705	active site
526224006706	catalytic tetrad [active]
526224006707	Uncharacterized conserved protein [Function unknown]; Region: COG4925
526224006708	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
526224006709	Competence protein; Region: Competence; pfam03772
526224006710	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
526224006711	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
526224006712	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
526224006713	Transglycosylase; Region: Transgly; pfam00912
526224006714	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
526224006715	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224006716	dimerization interface [polypeptide binding]; other site
526224006717	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224006718	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224006719	dimer interface [polypeptide binding]; other site
526224006720	putative CheW interface [polypeptide binding]; other site
526224006721	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
526224006722	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
526224006723	Flagellar protein FliS; Region: FliS; cl00654
526224006724	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
526224006725	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
526224006726	active site
526224006727	catalytic tetrad [active]
526224006728	AAA domain; Region: AAA_21; pfam13304
526224006729	AAA domain; Region: AAA_21; pfam13304
526224006730	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
526224006731	flagellar basal-body rod protein FlgB; Region: FlgB; TIGR01396
526224006732	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
526224006733	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
526224006734	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
526224006735	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
526224006736	integral membrane protein MviN; Region: mviN; TIGR01695
526224006737	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
526224006738	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224006739	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224006740	dimer interface [polypeptide binding]; other site
526224006741	putative CheW interface [polypeptide binding]; other site
526224006742	Rod binding protein; Region: Rod-binding; pfam10135
526224006743	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
526224006744	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
526224006745	DNA polymerase I; Provisional; Region: PRK05755
526224006746	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
526224006747	active site
526224006748	metal binding site 1 [ion binding]; metal-binding site
526224006749	putative 5' ssDNA interaction site; other site
526224006750	metal binding site 3; metal-binding site
526224006751	metal binding site 2 [ion binding]; metal-binding site
526224006752	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
526224006753	putative DNA binding site [nucleotide binding]; other site
526224006754	putative metal binding site [ion binding]; other site
526224006755	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
526224006756	active site
526224006757	catalytic site [active]
526224006758	substrate binding site [chemical binding]; other site
526224006759	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
526224006760	active site
526224006761	DNA binding site [nucleotide binding]
526224006762	catalytic site [active]
526224006763	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
526224006764	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
526224006765	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
526224006766	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
526224006767	catalytic site [active]
526224006768	G-X2-G-X-G-K; other site
526224006769	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
526224006770	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
526224006771	active site
526224006772	HIGH motif; other site
526224006773	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
526224006774	active site
526224006775	KMSKS motif; other site
526224006776	Response regulator receiver domain; Region: Response_reg; pfam00072
526224006777	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
526224006778	active site
526224006779	phosphorylation site [posttranslational modification]
526224006780	intermolecular recognition site; other site
526224006781	dimerization interface [polypeptide binding]; other site
526224006782	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
526224006783	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
526224006784	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
526224006785	NADP binding site [chemical binding]; other site
526224006786	homopentamer interface [polypeptide binding]; other site
526224006787	substrate binding site [chemical binding]; other site
526224006788	active site
526224006789	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
526224006790	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
526224006791	active site
526224006792	HIGH motif; other site
526224006793	nucleotide binding site [chemical binding]; other site
526224006794	Transcriptional regulators [Transcription]; Region: PurR; COG1609
526224006795	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
526224006796	DNA binding site [nucleotide binding]
526224006797	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
526224006798	ligand binding site [chemical binding]; other site
526224006799	dimerization interface [polypeptide binding]; other site
526224006800	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
526224006801	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
526224006802	Predicted permeases [General function prediction only]; Region: COG0701
526224006803	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
526224006804	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
526224006805	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
526224006806	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224006807	dimer interface [polypeptide binding]; other site
526224006808	conserved gate region; other site
526224006809	putative PBP binding loops; other site
526224006810	ABC-ATPase subunit interface; other site
526224006811	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
526224006812	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
526224006813	Walker A/P-loop; other site
526224006814	ATP binding site [chemical binding]; other site
526224006815	Q-loop/lid; other site
526224006816	ABC transporter signature motif; other site
526224006817	Walker B; other site
526224006818	D-loop; other site
526224006819	H-loop/switch region; other site
526224006820	Alkylmercury lyase; Region: MerB; pfam03243
526224006821	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
526224006822	putative active site [active]
526224006823	catalytic site [active]
526224006824	DEAD-like helicases superfamily; Region: DEXDc; smart00487
526224006825	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224006826	ATP binding site [chemical binding]; other site
526224006827	putative Mg++ binding site [ion binding]; other site
526224006828	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
526224006829	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224006830	nucleotide binding region [chemical binding]; other site
526224006831	ATP-binding site [chemical binding]; other site
526224006832	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
526224006833	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
526224006834	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
526224006835	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
526224006836	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
526224006837	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
526224006838	L-aspartate oxidase; Provisional; Region: PRK06175
526224006839	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
526224006840	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
526224006841	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
526224006842	hypothetical protein; Provisional; Region: PRK10621
526224006843	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
526224006844	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
526224006845	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
526224006846	inhibitor-cofactor binding pocket; inhibition site
526224006847	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224006848	catalytic residue [active]
526224006849	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224006850	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224006851	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
526224006852	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
526224006853	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
526224006854	Winged helix-turn helix; Region: HTH_29; pfam13551
526224006855	Homeodomain-like domain; Region: HTH_23; pfam13384
526224006856	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
526224006857	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
526224006858	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
526224006859	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
526224006860	active site
526224006861	HIGH motif; other site
526224006862	nucleotide binding site [chemical binding]; other site
526224006863	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
526224006864	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
526224006865	active site
526224006866	KMSKS motif; other site
526224006867	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
526224006868	tRNA binding surface [nucleotide binding]; other site
526224006869	anticodon binding site; other site
526224006870	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
526224006871	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
526224006872	RelB antitoxin; Region: RelB; cl01171
526224006873	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
526224006874	Methyltransferase domain; Region: Methyltransf_24; pfam13578
526224006875	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
526224006876	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
526224006877	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
526224006878	active site
526224006879	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
526224006880	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
526224006881	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224006882	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224006883	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
526224006884	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
526224006885	zinc binding site [ion binding]; other site
526224006886	putative ligand binding site [chemical binding]; other site
526224006887	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
526224006888	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
526224006889	TM-ABC transporter signature motif; other site
526224006890	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
526224006891	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224006892	Walker A/P-loop; other site
526224006893	ATP binding site [chemical binding]; other site
526224006894	Q-loop/lid; other site
526224006895	ABC transporter signature motif; other site
526224006896	Walker B; other site
526224006897	D-loop; other site
526224006898	H-loop/switch region; other site
526224006899	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
526224006900	DinB family; Region: DinB; cl17821
526224006901	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
526224006902	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
526224006903	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
526224006904	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
526224006905	catalytic residue [active]
526224006906	putative FPP diphosphate  binding site; other site
526224006907	putative FPP binding hydrophobic cleft; other site
526224006908	dimer interface [polypeptide binding]; other site
526224006909	putative IPP diphosphate binding site; other site
526224006910	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
526224006911	ribosome recycling factor; Reviewed; Region: frr; PRK00083
526224006912	hinge region; other site
526224006913	Protein of unknown function (DUF523); Region: DUF523; pfam04463
526224006914	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
526224006915	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
526224006916	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
526224006917	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
526224006918	Walker A/P-loop; other site
526224006919	ATP binding site [chemical binding]; other site
526224006920	Q-loop/lid; other site
526224006921	ABC transporter signature motif; other site
526224006922	Walker B; other site
526224006923	D-loop; other site
526224006924	H-loop/switch region; other site
526224006925	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
526224006926	mce related protein; Region: MCE; pfam02470
526224006927	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
526224006928	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
526224006929	active site
526224006930	dimerization interface [polypeptide binding]; other site
526224006931	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
526224006932	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
526224006933	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
526224006934	alpha subunit interaction interface [polypeptide binding]; other site
526224006935	Walker A motif; other site
526224006936	ATP binding site [chemical binding]; other site
526224006937	Walker B motif; other site
526224006938	inhibitor binding site; inhibition site
526224006939	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
526224006940	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
526224006941	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
526224006942	dimerization interface [polypeptide binding]; other site
526224006943	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
526224006944	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224006945	dimer interface [polypeptide binding]; other site
526224006946	putative CheW interface [polypeptide binding]; other site
526224006947	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
526224006948	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224006949	ligand binding site [chemical binding]; other site
526224006950	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
526224006951	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
526224006952	active site
526224006953	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
526224006954	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
526224006955	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
526224006956	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
526224006957	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
526224006958	TPP-binding site; other site
526224006959	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
526224006960	PYR/PP interface [polypeptide binding]; other site
526224006961	dimer interface [polypeptide binding]; other site
526224006962	TPP binding site [chemical binding]; other site
526224006963	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
526224006964	DNA repair protein RadA; Provisional; Region: PRK11823
526224006965	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
526224006966	Walker A motif; other site
526224006967	ATP binding site [chemical binding]; other site
526224006968	Walker B motif; other site
526224006969	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
526224006970	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224006971	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224006972	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
526224006973	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
526224006974	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
526224006975	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
526224006976	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
526224006977	active site
526224006978	aspartate aminotransferase; Provisional; Region: PRK07568
526224006979	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224006980	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224006981	homodimer interface [polypeptide binding]; other site
526224006982	catalytic residue [active]
526224006983	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
526224006984	Walker A/P-loop; other site
526224006985	ATP binding site [chemical binding]; other site
526224006986	AAA ATPase domain; Region: AAA_15; pfam13175
526224006987	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
526224006988	Phosphotransferase enzyme family; Region: APH; pfam01636
526224006989	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
526224006990	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182
526224006991	radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167
526224006992	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224006993	FeS/SAM binding site; other site
526224006994	Protein of unknown function (DUF3641); Region: DUF3641; pfam12345
526224006995	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
526224006996	active site residue [active]
526224006997	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
526224006998	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
526224006999	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224007000	homodimer interface [polypeptide binding]; other site
526224007001	catalytic residue [active]
526224007002	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
526224007003	Rubrerythrin [Energy production and conversion]; Region: COG1592
526224007004	binuclear metal center [ion binding]; other site
526224007005	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
526224007006	iron binding site [ion binding]; other site
526224007007	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
526224007008	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
526224007009	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
526224007010	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
526224007011	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
526224007012	hinge; other site
526224007013	active site
526224007014	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
526224007015	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224007016	substrate binding pocket [chemical binding]; other site
526224007017	membrane-bound complex binding site; other site
526224007018	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
526224007019	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224007020	membrane-bound complex binding site; other site
526224007021	hinge residues; other site
526224007022	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
526224007023	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
526224007024	Ligand binding site; other site
526224007025	Putative Catalytic site; other site
526224007026	DXD motif; other site
526224007027	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224007028	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
526224007029	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224007030	FeS/SAM binding site; other site
526224007031	Putative regulatory protein; Region: CxxC_CXXC_SSSS; smart00834
526224007032	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
526224007033	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
526224007034	nucleotide binding site [chemical binding]; other site
526224007035	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
526224007036	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
526224007037	Walker A/P-loop; other site
526224007038	ATP binding site [chemical binding]; other site
526224007039	Q-loop/lid; other site
526224007040	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
526224007041	ABC transporter signature motif; other site
526224007042	Walker B; other site
526224007043	D-loop; other site
526224007044	H-loop/switch region; other site
526224007045	ATP-NAD kinase; Region: NAD_kinase; pfam01513
526224007046	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
526224007047	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
526224007048	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
526224007049	putative acyl-acceptor binding pocket; other site
526224007050	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
526224007051	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
526224007052	hexamer interface [polypeptide binding]; other site
526224007053	ligand binding site [chemical binding]; other site
526224007054	putative active site [active]
526224007055	NAD(P) binding site [chemical binding]; other site
526224007056	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
526224007057	4Fe-4S binding domain; Region: Fer4_6; pfam12837
526224007058	4Fe-4S binding domain; Region: Fer4; pfam00037
526224007059	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
526224007060	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224007061	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007062	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007063	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007064	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
526224007065	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
526224007066	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
526224007067	Interdomain contacts; other site
526224007068	Cytokine receptor motif; other site
526224007069	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224007070	binding surface
526224007071	TPR motif; other site
526224007072	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
526224007073	dimerization interface [polypeptide binding]; other site
526224007074	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
526224007075	dimer interface [polypeptide binding]; other site
526224007076	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
526224007077	putative CheW interface [polypeptide binding]; other site
526224007078	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
526224007079	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
526224007080	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224007081	FeS/SAM binding site; other site
526224007082	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
526224007083	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
526224007084	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
526224007085	G1 box; other site
526224007086	GTP/Mg2+ binding site [chemical binding]; other site
526224007087	Switch I region; other site
526224007088	G2 box; other site
526224007089	Switch II region; other site
526224007090	G3 box; other site
526224007091	G4 box; other site
526224007092	G5 box; other site
526224007093	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
526224007094	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
526224007095	FeS/SAM binding site; other site
526224007096	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
526224007097	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
526224007098	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
526224007099	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
526224007100	Ligand binding site; other site
526224007101	metal-binding site
526224007102	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
526224007103	dinuclear metal binding motif [ion binding]; other site
526224007104	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
526224007105	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
526224007106	active site
526224007107	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
526224007108	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
526224007109	substrate binding pocket [chemical binding]; other site
526224007110	membrane-bound complex binding site; other site
526224007111	hinge residues; other site
526224007112	xanthine permease; Region: pbuX; TIGR03173
526224007113	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
526224007114	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; cl08390
526224007115	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
526224007116	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
526224007117	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
526224007118	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
526224007119	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
526224007120	carbamate kinase; Reviewed; Region: PRK12686
526224007121	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
526224007122	putative substrate binding site [chemical binding]; other site
526224007123	nucleotide binding site [chemical binding]; other site
526224007124	nucleotide binding site [chemical binding]; other site
526224007125	homodimer interface [polypeptide binding]; other site
526224007126	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
526224007127	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
526224007128	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
526224007129	peptidase; Reviewed; Region: PRK13004
526224007130	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
526224007131	putative metal binding site [ion binding]; other site
526224007132	putative dimer interface [polypeptide binding]; other site
526224007133	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
526224007134	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
526224007135	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
526224007136	catalytic residue [active]
526224007137	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
526224007138	YheO-like PAS domain; Region: PAS_6; pfam08348
526224007139	HTH domain; Region: HTH_22; pfam13309
526224007140	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
526224007141	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
526224007142	active site
526224007143	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
526224007144	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
526224007145	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224007146	selenium-dependent molybdenum hydroxylase 1; Region: Se_dep_Molyb_1; TIGR03311
526224007147	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
526224007148	catalytic loop [active]
526224007149	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
526224007150	iron binding site [ion binding]; other site
526224007151	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
526224007152	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
526224007153	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
526224007154	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
526224007155	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
526224007156	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
526224007157	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
526224007158	putative substrate binding site [chemical binding]; other site
526224007159	putative ATP binding site [chemical binding]; other site
526224007160	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cl00257
526224007161	IHF dimer interface [polypeptide binding]; other site
526224007162	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
526224007163	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
526224007164	catalytic residues [active]
526224007165	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
526224007166	MarR family; Region: MarR_2; cl17246
526224007167	Predicted membrane protein [Function unknown]; Region: COG2364
526224007168	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
526224007169	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
526224007170	dimer interface [polypeptide binding]; other site
526224007171	active site
526224007172	acyl carrier protein; Provisional; Region: acpP; PRK00982
526224007173	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
526224007174	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
526224007175	NAD(P) binding site [chemical binding]; other site
526224007176	homotetramer interface [polypeptide binding]; other site
526224007177	homodimer interface [polypeptide binding]; other site
526224007178	active site
526224007179	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
526224007180	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
526224007181	active site
526224007182	substrate binding site [chemical binding]; other site
526224007183	metal binding site [ion binding]; metal-binding site
526224007184	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007185	ligand binding site [chemical binding]; other site
526224007186	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007187	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007188	ligand binding site [chemical binding]; other site
526224007189	flexible hinge region; other site
526224007190	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
526224007191	Protein of unknown function (DUF721); Region: DUF721; pfam05258
526224007192	TPR repeat; Region: TPR_11; pfam13414
526224007193	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224007194	binding surface
526224007195	TPR motif; other site
526224007196	TPR repeat; Region: TPR_11; pfam13414
526224007197	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007198	binding surface
526224007199	TPR motif; other site
526224007200	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224007201	flagellar assembly protein J; Reviewed; Region: PRK06041
526224007202	galactokinase; Provisional; Region: PRK05322
526224007203	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
526224007204	peptide chain release factor 2; Validated; Region: prfB; PRK00578
526224007205	PCRF domain; Region: PCRF; pfam03462
526224007206	RF-1 domain; Region: RF-1; pfam00472
526224007207	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007208	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007209	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007210	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007211	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007212	FOG: Ankyrin repeat [General function prediction only]; Region: Arp; COG0666
526224007213	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224007214	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
526224007215	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
526224007216	catalytic triad [active]
526224007217	conserved cis-peptide bond; other site
526224007218	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
526224007219	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
526224007220	DNA binding site [nucleotide binding]
526224007221	active site
526224007222	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
526224007223	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
526224007224	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
526224007225	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
526224007226	putative NAD(P) binding site [chemical binding]; other site
526224007227	Stage II sporulation protein; Region: SpoIID; pfam08486
526224007228	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
526224007229	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
526224007230	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
526224007231	NAD(P) binding site [chemical binding]; other site
526224007232	catalytic residues [active]
526224007233	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224007234	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
526224007235	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
526224007236	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
526224007237	N-acetyl-D-glucosamine binding site [chemical binding]; other site
526224007238	catalytic residue [active]
526224007239	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224007240	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
526224007241	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
526224007242	homodimer interface [polypeptide binding]; other site
526224007243	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224007244	catalytic residue [active]
526224007245	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
526224007246	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
526224007247	ligand binding site [chemical binding]; other site
526224007248	NAD binding site [chemical binding]; other site
526224007249	dimerization interface [polypeptide binding]; other site
526224007250	catalytic site [active]
526224007251	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
526224007252	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
526224007253	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
526224007254	motif II; other site
526224007255	citrate synthase; Provisional; Region: PRK14032
526224007256	Citrate synthase; Region: Citrate_synt; pfam00285
526224007257	oxalacetate binding site [chemical binding]; other site
526224007258	citrylCoA binding site [chemical binding]; other site
526224007259	coenzyme A binding site [chemical binding]; other site
526224007260	catalytic triad [active]
526224007261	isocitrate dehydrogenase; Validated; Region: PRK07362
526224007262	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
526224007263	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
526224007264	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
526224007265	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007266	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007267	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224007268	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007269	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007270	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007271	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007272	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007273	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007274	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007275	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
526224007276	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007277	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
526224007278	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
526224007279	aconitate hydratase; Validated; Region: PRK07229
526224007280	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
526224007281	substrate binding site [chemical binding]; other site
526224007282	ligand binding site [chemical binding]; other site
526224007283	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
526224007284	substrate binding site [chemical binding]; other site
526224007285	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
526224007286	dimer interface [polypeptide binding]; other site
526224007287	ATP cone domain; Region: ATP-cone; pfam03477
526224007288	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
526224007289	ribonucleoside-diphosphate reductase, alpha subunit; Region: NrdE_NrdA; TIGR02506
526224007290	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
526224007291	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
526224007292	dimer interface [polypeptide binding]; other site
526224007293	putative radical transfer pathway; other site
526224007294	diiron center [ion binding]; other site
526224007295	tyrosyl radical; other site
526224007296	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
526224007297	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
526224007298	metal binding site [ion binding]; metal-binding site
526224007299	dimer interface [polypeptide binding]; other site
526224007300	OPT oligopeptide transporter protein; Region: OPT; cl14607
526224007301	putative oligopeptide transporter, OPT family; Region: TIGR00733
526224007302	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
526224007303	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
526224007304	dimer interface [polypeptide binding]; other site
526224007305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224007306	catalytic residue [active]
526224007307	serine O-acetyltransferase; Region: cysE; TIGR01172
526224007308	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
526224007309	trimer interface [polypeptide binding]; other site
526224007310	active site
526224007311	substrate binding site [chemical binding]; other site
526224007312	CoA binding site [chemical binding]; other site
526224007313	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
526224007314	catalytic site [active]
526224007315	BNR repeat-like domain; Region: BNR_2; pfam13088
526224007316	Asp-box motif; other site
526224007317	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
526224007318	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
526224007319	substrate binding site [chemical binding]; other site
526224007320	ATP binding site [chemical binding]; other site
526224007321	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
526224007322	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
526224007323	nucleotide binding site [chemical binding]; other site
526224007324	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
526224007325	Clp amino terminal domain; Region: Clp_N; pfam02861
526224007326	Clp amino terminal domain; Region: Clp_N; pfam02861
526224007327	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224007328	Walker A motif; other site
526224007329	ATP binding site [chemical binding]; other site
526224007330	Walker B motif; other site
526224007331	arginine finger; other site
526224007332	Protein-interacting V-domain of mammalian Alix and related domains; Region: V_Alix_like; cl14654
526224007333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224007334	Walker A motif; other site
526224007335	ATP binding site [chemical binding]; other site
526224007336	Walker B motif; other site
526224007337	arginine finger; other site
526224007338	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
526224007339	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
526224007340	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
526224007341	catalytic triad [active]
526224007342	amino acid transporter; Region: 2A0306; TIGR00909
526224007343	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
526224007344	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224007345	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224007346	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
526224007347	Glycine reductase complex selenoprotein A; Region: GRDA; cl04705
526224007348	Glycine reductase complex selenoprotein A; Region: GRDA; cl04705
526224007349	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; pfam07355
526224007350	glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917
526224007351	glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917
526224007352	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
526224007353	dimer interface [polypeptide binding]; other site
526224007354	active site
526224007355	Fatty acid synthesis protein; Region: FA_synthesis; cl17261
526224007356	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
526224007357	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
526224007358	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
526224007359	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
526224007360	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
526224007361	methionine sulfoxide reductase B; Provisional; Region: PRK05508
526224007362	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
526224007363	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
526224007364	Coenzyme A binding pocket [chemical binding]; other site
526224007365	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
526224007366	rRNA interaction site [nucleotide binding]; other site
526224007367	S8 interaction site; other site
526224007368	putative laminin-1 binding site; other site
526224007369	elongation factor Ts; Provisional; Region: tsf; PRK09377
526224007370	UBA/TS-N domain; Region: UBA; pfam00627
526224007371	Elongation factor TS; Region: EF_TS; pfam00889
526224007372	Elongation factor TS; Region: EF_TS; pfam00889
526224007373	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007374	TPR motif; other site
526224007375	binding surface
526224007376	TPR repeat; Region: TPR_11; pfam13414
526224007377	TPR repeat; Region: TPR_11; pfam13414
526224007378	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007379	binding surface
526224007380	TPR motif; other site
526224007381	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
526224007382	Biotin carboxylase [Lipid metabolism]; Region: AccC; COG0439
526224007383	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
526224007384	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
526224007385	dimer interface [polypeptide binding]; other site
526224007386	putative tRNA-binding site [nucleotide binding]; other site
526224007387	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
526224007388	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
526224007389	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
526224007390	ATP binding site [chemical binding]; other site
526224007391	putative Mg++ binding site [ion binding]; other site
526224007392	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
526224007393	nucleotide binding region [chemical binding]; other site
526224007394	ATP-binding site [chemical binding]; other site
526224007395	Tetratricopeptide repeat; Region: TPR_6; pfam13174
526224007396	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
526224007397	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
526224007398	NAD binding site [chemical binding]; other site
526224007399	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
526224007400	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
526224007401	peptide binding site [polypeptide binding]; other site
526224007402	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
526224007403	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
526224007404	N-acetyl-D-glucosamine binding site [chemical binding]; other site
526224007405	catalytic residue [active]
526224007406	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
526224007407	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224007408	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
526224007409	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
526224007410	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
526224007411	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
526224007412	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
526224007413	PhoU domain; Region: PhoU; pfam01895
526224007414	TM2 domain; Region: TM2; pfam05154
526224007415	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
526224007416	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
526224007417	Mg2+ binding site [ion binding]; other site
526224007418	G-X-G motif; other site
526224007419	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
526224007420	anchoring element; other site
526224007421	dimer interface [polypeptide binding]; other site
526224007422	ATP binding site [chemical binding]; other site
526224007423	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
526224007424	active site
526224007425	putative metal-binding site [ion binding]; other site
526224007426	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
526224007427	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
526224007428	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
526224007429	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
526224007430	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
526224007431	active site
526224007432	phosphorylation site [posttranslational modification]
526224007433	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
526224007434	active site
526224007435	P-loop; other site
526224007436	phosphorylation site [posttranslational modification]
526224007437	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
526224007438	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
526224007439	active site
526224007440	metal binding site [ion binding]; metal-binding site
526224007441	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
526224007442	oligoendopeptidase F; Region: pepF; TIGR00181
526224007443	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
526224007444	active site
526224007445	Zn binding site [ion binding]; other site
526224007446	TM2 domain; Region: TM2; pfam05154
526224007447	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
526224007448	dimer interface [polypeptide binding]; other site
526224007449	pyridoxal binding site [chemical binding]; other site
526224007450	ATP binding site [chemical binding]; other site
526224007451	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
526224007452	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
526224007453	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
526224007454	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
526224007455	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
526224007456	Soluble P-type ATPase [General function prediction only]; Region: COG4087
526224007457	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
526224007458	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007459	TPR motif; other site
526224007460	binding surface
526224007461	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224007462	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007463	binding surface
526224007464	Tetratricopeptide repeat; Region: TPR_16; pfam13432
526224007465	TPR motif; other site
526224007466	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
526224007467	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
526224007468	binding surface
526224007469	TPR motif; other site
526224007470	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
526224007471	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224007472	S-adenosylmethionine binding site [chemical binding]; other site
526224007473	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
526224007474	N-terminal putative catalytic domain of mainly uncharacterized prokaryotic proteins similar to archaeal thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU_like_1; cd10797
526224007475	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
526224007476	active site
526224007477	catalytic site [active]
526224007478	Domain of unknown function (DUF3536); Region: DUF3536; pfam12055
526224007479	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
526224007480	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
526224007481	RNA binding surface [nucleotide binding]; other site
526224007482	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
526224007483	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007484	ligand binding site [chemical binding]; other site
526224007485	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007486	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224007487	ligand binding site [chemical binding]; other site
526224007488	flexible hinge region; other site
526224007489	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224007490	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007491	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007492	ligand binding site [chemical binding]; other site
526224007493	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007494	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007495	ligand binding site [chemical binding]; other site
526224007496	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007497	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
526224007498	ligand binding site [chemical binding]; other site
526224007499	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007500	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007501	ligand binding site [chemical binding]; other site
526224007502	flexible hinge region; other site
526224007503	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007504	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007505	ligand binding site [chemical binding]; other site
526224007506	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
526224007507	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
526224007508	ligand binding site [chemical binding]; other site
526224007509	flexible hinge region; other site
526224007510	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
526224007511	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
526224007512	catalytic residues [active]
526224007513	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
526224007514	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224007515	S-adenosylmethionine binding site [chemical binding]; other site
526224007516	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
526224007517	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
526224007518	glutamate dehydrogenase; Provisional; Region: PRK09414
526224007519	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
526224007520	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
526224007521	NAD(P) binding pocket [chemical binding]; other site
526224007522	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007523	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007524	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007525	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007526	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
526224007527	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
526224007528	metal binding site [ion binding]; metal-binding site
526224007529	dimer interface [polypeptide binding]; other site
526224007530	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007531	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
526224007532	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007533	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224007534	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007535	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007536	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224007537	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007538	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
526224007539	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007540	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224007541	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007542	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
526224007543	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007544	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007545	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007546	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
526224007547	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
526224007548	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
526224007549	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
526224007550	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
526224007551	Ferritin-like domain; Region: Ferritin; pfam00210
526224007552	ferroxidase diiron center [ion binding]; other site
526224007553	agmatinase; Region: agmatinase; TIGR01230
526224007554	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
526224007555	putative active site [active]
526224007556	Mn binding site [ion binding]; other site
526224007557	spermidine synthase; Provisional; Region: PRK00811
526224007558	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
526224007559	S-adenosylmethionine binding site [chemical binding]; other site
526224007560	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
526224007561	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
526224007562	homodimer interface [polypeptide binding]; other site
526224007563	pyridoxal 5'-phosphate binding site [chemical binding]; other site
526224007564	catalytic residue [active]
526224007565	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
526224007566	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
526224007567	Ferritin-like domain; Region: Ferritin; pfam00210
526224007568	ferroxidase diiron center [ion binding]; other site
526224007569	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
526224007570	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
526224007571	Walker A/P-loop; other site
526224007572	ATP binding site [chemical binding]; other site
526224007573	Q-loop/lid; other site
526224007574	ABC transporter signature motif; other site
526224007575	Walker B; other site
526224007576	D-loop; other site
526224007577	H-loop/switch region; other site
526224007578	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
526224007579	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
526224007580	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
526224007581	Peptidase family U32; Region: Peptidase_U32; pfam01136
526224007582	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
526224007583	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
526224007584	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
526224007585	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
526224007586	glycogen synthase; Provisional; Region: glgA; PRK00654
526224007587	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
526224007588	ADP-binding pocket [chemical binding]; other site
526224007589	homodimer interface [polypeptide binding]; other site
526224007590	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
526224007591	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
526224007592	LexA repressor; Validated; Region: PRK00215
526224007593	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
526224007594	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
526224007595	Catalytic site [active]
526224007596	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
526224007597	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
526224007598	substrate binding site [chemical binding]; other site
526224007599	hexamer interface [polypeptide binding]; other site
526224007600	metal binding site [ion binding]; metal-binding site
526224007601	ribonuclease III; Reviewed; Region: rnc; PRK00102
526224007602	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
526224007603	dimerization interface [polypeptide binding]; other site
526224007604	active site
526224007605	metal binding site [ion binding]; metal-binding site
526224007606	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
526224007607	dsRNA binding site [nucleotide binding]; other site
526224007608	hypothetical protein; Provisional; Region: yieM; PRK10997
526224007609	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
526224007610	metal ion-dependent adhesion site (MIDAS); other site
526224007611	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
526224007612	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
526224007613	Walker A motif; other site
526224007614	ATP binding site [chemical binding]; other site
526224007615	Walker B motif; other site
526224007616	arginine finger; other site
526224007617	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
526224007618	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
526224007619	Walker A/P-loop; other site
526224007620	ATP binding site [chemical binding]; other site
526224007621	Q-loop/lid; other site
526224007622	ABC transporter signature motif; other site
526224007623	Walker B; other site
526224007624	D-loop; other site
526224007625	H-loop/switch region; other site
526224007626	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
526224007627	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
526224007628	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
526224007629	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
526224007630	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
526224007631	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
526224007632	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224007633	ligand binding site [chemical binding]; other site
526224007634	Uncharacterized conserved protein [Function unknown]; Region: COG1912
526224007635	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
526224007636	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
526224007637	intersubunit interface [polypeptide binding]; other site
526224007638	active site
526224007639	zinc binding site [ion binding]; other site
526224007640	Na+ binding site [ion binding]; other site
526224007641	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
526224007642	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
526224007643	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
526224007644	active site
526224007645	dimer interface [polypeptide binding]; other site
526224007646	motif 1; other site
526224007647	motif 2; other site
526224007648	motif 3; other site
526224007649	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
526224007650	anticodon binding site; other site
526224007651	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
526224007652	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
526224007653	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
526224007654	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
526224007655	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
526224007656	23S rRNA binding site [nucleotide binding]; other site
526224007657	L21 binding site [polypeptide binding]; other site
526224007658	L13 binding site [polypeptide binding]; other site
526224007659	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
526224007660	ligand binding site [chemical binding]; other site
526224007661	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
526224007662	ligand binding site [chemical binding]; other site
526224007663	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
526224007664	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
526224007665	RNA binding site [nucleotide binding]; other site
526224007666	active site
526224007667	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
526224007668	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
526224007669	putative substrate translocation pore; other site
526224007670	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
526224007671	PhoU domain; Region: PhoU; pfam01895
526224007672	PhoU domain; Region: PhoU; pfam01895
526224007673	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
526224007674	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
526224007675	Walker A/P-loop; other site
526224007676	ATP binding site [chemical binding]; other site
526224007677	Q-loop/lid; other site
526224007678	ABC transporter signature motif; other site
526224007679	Walker B; other site
526224007680	D-loop; other site
526224007681	H-loop/switch region; other site
526224007682	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
526224007683	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224007684	dimer interface [polypeptide binding]; other site
526224007685	conserved gate region; other site
526224007686	putative PBP binding loops; other site
526224007687	ABC-ATPase subunit interface; other site
526224007688	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
526224007689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
526224007690	dimer interface [polypeptide binding]; other site
526224007691	conserved gate region; other site
526224007692	putative PBP binding loops; other site
526224007693	ABC-ATPase subunit interface; other site
526224007694	PBP superfamily domain; Region: PBP_like_2; cl17296
526224007695	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
526224007696	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
526224007697	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
526224007698	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
526224007699	Coenzyme A binding pocket [chemical binding]; other site
526224007700	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
526224007701	putative nucleotide binding site [chemical binding]; other site
526224007702	uridine monophosphate binding site [chemical binding]; other site
526224007703	homohexameric interface [polypeptide binding]; other site
526224007704	hypothetical protein; Provisional; Region: PRK13665
526224007705	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
526224007706	nucleophile elbow; other site
526224007707	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
526224007708	binding surface
526224007709	TPR motif; other site