-- dump date   	20140619_005317
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1042417000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1042417000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417000003	Walker A motif; other site
1042417000004	ATP binding site [chemical binding]; other site
1042417000005	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1042417000006	DnaA box-binding interface [nucleotide binding]; other site
1042417000007	GrpE; Region: GrpE; pfam01025
1042417000008	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1042417000009	dimer interface [polypeptide binding]; other site
1042417000010	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1042417000011	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1042417000012	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1042417000013	nucleotide binding site [chemical binding]; other site
1042417000014	NEF interaction site [polypeptide binding]; other site
1042417000015	SBD interface [polypeptide binding]; other site
1042417000016	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1042417000017	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1042417000018	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1042417000019	dimer interface [polypeptide binding]; other site
1042417000020	putative tRNA-binding site [nucleotide binding]; other site
1042417000021	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417000022	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1042417000023	Walker A motif; other site
1042417000024	ATP binding site [chemical binding]; other site
1042417000025	Walker B motif; other site
1042417000026	arginine finger; other site
1042417000027	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1042417000028	thiamine phosphate binding site [chemical binding]; other site
1042417000029	active site
1042417000030	pyrophosphate binding site [ion binding]; other site
1042417000031	Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair]; Region: COG1525
1042417000032	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
1042417000033	Catalytic site; other site
1042417000034	potential frameshift: common BLAST hit: gi|300870218|ref|YP_003785089.1| PTS system glucose subfamily transporter subunit IIA
1042417000035	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417000036	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
1042417000037	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1042417000038	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417000039	ATP binding site [chemical binding]; other site
1042417000040	putative Mg++ binding site [ion binding]; other site
1042417000041	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417000042	nucleotide binding region [chemical binding]; other site
1042417000043	ATP-binding site [chemical binding]; other site
1042417000044	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1042417000045	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417000046	active site
1042417000047	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
1042417000048	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1042417000049	putative nucleotide binding site [chemical binding]; other site
1042417000050	uridine monophosphate binding site [chemical binding]; other site
1042417000051	homohexameric interface [polypeptide binding]; other site
1042417000052	hypothetical protein; Provisional; Region: PRK13665
1042417000053	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417000054	Zn2+ binding site [ion binding]; other site
1042417000055	Mg2+ binding site [ion binding]; other site
1042417000056	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1042417000057	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1042417000058	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1042417000059	catalytic residue [active]
1042417000060	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1042417000061	core domain interface [polypeptide binding]; other site
1042417000062	delta subunit interface [polypeptide binding]; other site
1042417000063	epsilon subunit interface [polypeptide binding]; other site
1042417000064	Core-2/I-Branching enzyme; Region: Branch; pfam02485
1042417000065	Core-2/I-Branching enzyme; Region: Branch; pfam02485
1042417000066	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1042417000067	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1042417000068	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1042417000069	beta subunit interaction interface [polypeptide binding]; other site
1042417000070	Walker A motif; other site
1042417000071	ATP binding site [chemical binding]; other site
1042417000072	Walker B motif; other site
1042417000073	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1042417000074	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
1042417000075	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1042417000076	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
1042417000077	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1042417000078	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1042417000079	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1042417000080	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
1042417000081	ATP synthase A chain; Region: ATP-synt_A; cl00413
1042417000082	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1042417000083	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1042417000084	anti sigma factor interaction site; other site
1042417000085	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1042417000086	regulatory phosphorylation site [posttranslational modification]; other site
1042417000087	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1042417000088	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1042417000089	active site
1042417000090	metal binding site [ion binding]; metal-binding site
1042417000091	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1042417000092	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000093	binding surface
1042417000094	TPR motif; other site
1042417000095	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000096	TPR motif; other site
1042417000097	binding surface
1042417000098	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000099	TPR motif; other site
1042417000100	binding surface
1042417000101	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000102	binding surface
1042417000103	TPR motif; other site
1042417000104	potential frameshift: common BLAST hit: gi|300870191|ref|YP_003785062.1| transcription antitermination protein NusB
1042417000105	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1042417000106	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1042417000107	active site
1042417000108	HIGH motif; other site
1042417000109	nucleotide binding site [chemical binding]; other site
1042417000110	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1042417000111	active site
1042417000112	KMSKS motif; other site
1042417000113	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1042417000114	tRNA binding surface [nucleotide binding]; other site
1042417000115	anticodon binding site; other site
1042417000116	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1042417000117	Predicted transcriptional regulators [Transcription]; Region: COG1695
1042417000118	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1042417000119	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1042417000120	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1042417000121	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1042417000122	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1042417000123	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1042417000124	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
1042417000125	putative active site [active]
1042417000126	putative NTP binding site [chemical binding]; other site
1042417000127	putative nucleic acid binding site [nucleotide binding]; other site
1042417000128	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1042417000129	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1042417000130	active site
1042417000131	catalytic site [active]
1042417000132	GAF domain; Region: GAF_3; pfam13492
1042417000133	GAF domain; Region: GAF_3; pfam13492
1042417000134	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1042417000135	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1042417000136	dimer interface [polypeptide binding]; other site
1042417000137	phosphorylation site [posttranslational modification]
1042417000138	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417000139	ATP binding site [chemical binding]; other site
1042417000140	Mg2+ binding site [ion binding]; other site
1042417000141	G-X-G motif; other site
1042417000142	potential frameshift: common BLAST hit: gi|300870181|ref|YP_003785052.1| MiaB-like tRNA modifying enzyme
1042417000143	cell division protein FtsZ; Region: ftsZ; TIGR00065
1042417000144	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1042417000145	nucleotide binding site [chemical binding]; other site
1042417000146	SulA interaction site; other site
1042417000147	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000148	binding surface
1042417000149	TPR motif; other site
1042417000150	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1042417000151	dephospho-CoA kinase; Region: TIGR00152
1042417000152	CoA-binding site [chemical binding]; other site
1042417000153	ATP-binding [chemical binding]; other site
1042417000154	Sporulation related domain; Region: SPOR; pfam05036
1042417000155	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
1042417000156	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417000157	FeS/SAM binding site; other site
1042417000158	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1042417000159	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1042417000160	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000161	TPR motif; other site
1042417000162	binding surface
1042417000163	TPR repeat; Region: TPR_11; pfam13414
1042417000164	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000165	binding surface
1042417000166	TPR motif; other site
1042417000167	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1042417000168	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1042417000169	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417000170	binding surface
1042417000171	TPR motif; other site
1042417000172	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1042417000173	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1042417000174	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1042417000175	pyruvate kinase; Provisional; Region: PRK05826
1042417000176	domain interfaces; other site
1042417000177	active site
1042417000178	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1042417000179	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1042417000180	NAD(P) binding site [chemical binding]; other site
1042417000181	homotetramer interface [polypeptide binding]; other site
1042417000182	homodimer interface [polypeptide binding]; other site
1042417000183	active site
1042417000184	acyl carrier protein; Provisional; Region: acpP; PRK00982
1042417000185	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1042417000186	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1042417000187	dimer interface [polypeptide binding]; other site
1042417000188	active site
1042417000189	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1042417000190	active site
1042417000191	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1042417000192	active site
1042417000193	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1042417000194	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1042417000195	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1042417000196	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1042417000197	hinge region; other site
1042417000198	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1042417000199	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1042417000200	catalytic residue [active]
1042417000201	putative FPP diphosphate  binding site; other site
1042417000202	putative FPP binding hydrophobic cleft; other site
1042417000203	dimer interface [polypeptide binding]; other site
1042417000204	putative IPP diphosphate binding site; other site
1042417000205	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1042417000206	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1042417000207	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1042417000208	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1042417000209	catalytic residue [active]
1042417000210	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417000211	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417000212	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1042417000213	catalytic residues [active]
1042417000214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1042417000215	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1042417000216	glycogen synthase; Provisional; Region: glgA; PRK00654
1042417000217	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1042417000218	ADP-binding pocket [chemical binding]; other site
1042417000219	homodimer interface [polypeptide binding]; other site
1042417000220	oligoendopeptidase F; Region: pepF; TIGR00181
1042417000221	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1042417000222	active site
1042417000223	Zn binding site [ion binding]; other site
1042417000224	TM2 domain; Region: TM2; pfam05154
1042417000225	potential frameshift: common BLAST hit: gi|300870146|ref|YP_003785017.1| threonyl-tRNA synthetase
1042417000226	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1042417000227	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1042417000228	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1042417000229	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1042417000230	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1042417000231	23S rRNA binding site [nucleotide binding]; other site
1042417000232	L21 binding site [polypeptide binding]; other site
1042417000233	L13 binding site [polypeptide binding]; other site
1042417000234	ribonucleoside-diphosphate reductase subunit alpha; Provisional; Region: nrdA; PHA02572
1042417000235	ATP cone domain; Region: ATP-cone; pfam03477
1042417000236	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
1042417000237	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
1042417000238	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1042417000239	dimer interface [polypeptide binding]; other site
1042417000240	putative radical transfer pathway; other site
1042417000241	diiron center [ion binding]; other site
1042417000242	tyrosyl radical; other site
1042417000243	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1042417000244	Sodium Bile acid symporter family; Region: SBF; pfam01758
1042417000245	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1042417000246	potential frameshift: common BLAST hit: gi|296125580|ref|YP_003632832.1| flavodoxin/nitric oxide synthase
1042417000247	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
1042417000248	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1042417000249	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
1042417000250	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1042417000251	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1042417000252	ligand binding site [chemical binding]; other site
1042417000253	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1042417000254	dimerization interface [polypeptide binding]; other site
1042417000255	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417000256	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417000257	dimer interface [polypeptide binding]; other site
1042417000258	putative CheW interface [polypeptide binding]; other site
1042417000259	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1042417000260	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1042417000261	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1042417000262	alpha subunit interaction interface [polypeptide binding]; other site
1042417000263	Walker A motif; other site
1042417000264	ATP binding site [chemical binding]; other site
1042417000265	Walker B motif; other site
1042417000266	inhibitor binding site; inhibition site
1042417000267	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1042417000268	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1042417000269	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1042417000270	active site
1042417000271	dimerization interface [polypeptide binding]; other site
1042417000272	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1042417000273	mce related protein; Region: MCE; pfam02470
1042417000274	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1042417000275	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1042417000276	Walker A/P-loop; other site
1042417000277	ATP binding site [chemical binding]; other site
1042417000278	Q-loop/lid; other site
1042417000279	ABC transporter signature motif; other site
1042417000280	Walker B; other site
1042417000281	D-loop; other site
1042417000282	H-loop/switch region; other site
1042417000283	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1042417000284	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1042417000285	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1042417000286	L-threonine dehydrogenase; Region: threonine_DH_like; cd08234
1042417000287	putative NAD(P) binding site [chemical binding]; other site
1042417000288	catalytic Zn binding site [ion binding]; other site
1042417000289	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1042417000290	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1042417000291	HIGH motif; other site
1042417000292	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1042417000293	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1042417000294	active site
1042417000295	KMSKS motif; other site
1042417000296	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1042417000297	tRNA binding surface [nucleotide binding]; other site
1042417000298	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417000299	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417000300	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000301	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000302	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000303	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000304	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000305	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000306	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000307	binding surface
1042417000308	TPR motif; other site
1042417000309	TPR repeat; Region: TPR_11; pfam13414
1042417000310	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000311	binding surface
1042417000312	TPR motif; other site
1042417000313	TPR repeat; Region: TPR_11; pfam13414
1042417000314	TPR repeat; Region: TPR_11; pfam13414
1042417000315	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000316	binding surface
1042417000317	TPR motif; other site
1042417000318	TPR repeat; Region: TPR_11; pfam13414
1042417000319	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000320	TPR motif; other site
1042417000321	binding surface
1042417000322	TPR repeat; Region: TPR_11; pfam13414
1042417000323	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000324	binding surface
1042417000325	TPR repeat; Region: TPR_11; pfam13414
1042417000326	TPR motif; other site
1042417000327	TPR repeat; Region: TPR_11; pfam13414
1042417000328	TPR repeat; Region: TPR_11; pfam13414
1042417000329	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000330	binding surface
1042417000331	TPR motif; other site
1042417000332	TPR repeat; Region: TPR_11; pfam13414
1042417000333	TPR repeat; Region: TPR_11; pfam13414
1042417000334	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000335	binding surface
1042417000336	TPR motif; other site
1042417000337	TPR repeat; Region: TPR_11; pfam13414
1042417000338	TPR repeat; Region: TPR_11; pfam13414
1042417000339	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000340	binding surface
1042417000341	TPR motif; other site
1042417000342	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417000343	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417000344	peptide binding site [polypeptide binding]; other site
1042417000345	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1042417000346	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1042417000347	putative NAD(P) binding site [chemical binding]; other site
1042417000348	putative substrate binding site [chemical binding]; other site
1042417000349	catalytic Zn binding site [ion binding]; other site
1042417000350	structural Zn binding site [ion binding]; other site
1042417000351	dimer interface [polypeptide binding]; other site
1042417000352	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417000353	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417000354	peptide binding site [polypeptide binding]; other site
1042417000355	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1042417000356	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1042417000357	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1042417000358	mannonate dehydratase; Provisional; Region: PRK03906
1042417000359	mannonate dehydratase; Region: uxuA; TIGR00695
1042417000360	Glucuronate isomerase; Region: UxaC; pfam02614
1042417000361	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1042417000362	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1042417000363	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1042417000364	active site
1042417000365	intersubunit interface [polypeptide binding]; other site
1042417000366	catalytic residue [active]
1042417000367	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1042417000368	homodimer interface [polypeptide binding]; other site
1042417000369	MazG family protein; Region: mazG; TIGR00444
1042417000370	metal binding site [ion binding]; metal-binding site
1042417000371	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1042417000372	homodimer interface [polypeptide binding]; other site
1042417000373	active site
1042417000374	putative chemical substrate binding site [chemical binding]; other site
1042417000375	metal binding site [ion binding]; metal-binding site
1042417000376	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1042417000377	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1042417000378	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1042417000379	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1042417000380	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1042417000381	putative active site [active]
1042417000382	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1042417000383	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1042417000384	putative active site [active]
1042417000385	putative metal binding site [ion binding]; other site
1042417000386	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1042417000387	Domain of unknown function DUF21; Region: DUF21; pfam01595
1042417000388	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1042417000389	Transporter associated domain; Region: CorC_HlyC; smart01091
1042417000390	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1042417000391	amidase catalytic site [active]
1042417000392	Zn binding residues [ion binding]; other site
1042417000393	substrate binding site [chemical binding]; other site
1042417000394	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
1042417000395	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1042417000396	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1042417000397	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1042417000398	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1042417000399	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417000400	active site
1042417000401	phosphorylation site [posttranslational modification]
1042417000402	intermolecular recognition site; other site
1042417000403	dimerization interface [polypeptide binding]; other site
1042417000404	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1042417000405	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1042417000406	putative binding surface; other site
1042417000407	active site
1042417000408	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1042417000409	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417000410	ATP binding site [chemical binding]; other site
1042417000411	Mg2+ binding site [ion binding]; other site
1042417000412	G-X-G motif; other site
1042417000413	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1042417000414	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1042417000415	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1042417000416	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
1042417000417	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417000418	CheD chemotactic sensory transduction; Region: CheD; cl00810
1042417000419	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1042417000420	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417000421	active site
1042417000422	phosphorylation site [posttranslational modification]
1042417000423	intermolecular recognition site; other site
1042417000424	dimerization interface [polypeptide binding]; other site
1042417000425	CheB methylesterase; Region: CheB_methylest; pfam01339
1042417000426	UGMP family protein; Validated; Region: PRK09604
1042417000427	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1042417000428	TPR repeat; Region: TPR_11; pfam13414
1042417000429	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000430	binding surface
1042417000431	TPR motif; other site
1042417000432	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417000433	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417000434	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417000435	Walker A/P-loop; other site
1042417000436	ATP binding site [chemical binding]; other site
1042417000437	Q-loop/lid; other site
1042417000438	ABC transporter signature motif; other site
1042417000439	Walker B; other site
1042417000440	D-loop; other site
1042417000441	H-loop/switch region; other site
1042417000442	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417000443	dimer interface [polypeptide binding]; other site
1042417000444	conserved gate region; other site
1042417000445	putative PBP binding loops; other site
1042417000446	ABC-ATPase subunit interface; other site
1042417000447	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1042417000448	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417000449	Coenzyme A binding pocket [chemical binding]; other site
1042417000450	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1042417000451	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1042417000452	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1042417000453	ACT_3PGDH-like CD includes the C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-like; cd04879
1042417000454	L-serine binding site [chemical binding]; other site
1042417000455	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1042417000456	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1042417000457	active site
1042417000458	Int/Topo IB signature motif; other site
1042417000459	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1042417000460	potential frameshift: common BLAST hit: gi|300870080|ref|YP_003784951.1| putative phosphate regulon sensor protein
1042417000461	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1042417000462	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417000463	active site
1042417000464	phosphorylation site [posttranslational modification]
1042417000465	intermolecular recognition site; other site
1042417000466	dimerization interface [polypeptide binding]; other site
1042417000467	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1042417000468	DNA binding site [nucleotide binding]
1042417000469	putative oxidoreductase; Provisional; Region: PRK12831
1042417000470	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417000471	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417000472	N-terminal putative catalytic domain of mainly uncharacterized prokaryotic proteins similar to archaeal thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57); Region: GH57N_APU_like_1; cd10797
1042417000473	active site
1042417000474	catalytic site [active]
1042417000475	Domain of unknown function (DUF3536); Region: DUF3536; pfam12055
1042417000476	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
1042417000477	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1042417000478	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417000479	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1042417000480	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1042417000481	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417000482	homodimer interface [polypeptide binding]; other site
1042417000483	catalytic residue [active]
1042417000484	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1042417000485	YheO-like PAS domain; Region: PAS_6; pfam08348
1042417000486	HTH domain; Region: HTH_22; pfam13309
1042417000487	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1042417000488	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417000489	HEAT repeats; Region: HEAT_2; pfam13646
1042417000490	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1042417000491	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1042417000492	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1042417000493	dimerization domain swap beta strand [polypeptide binding]; other site
1042417000494	regulatory protein interface [polypeptide binding]; other site
1042417000495	active site
1042417000496	regulatory phosphorylation site [posttranslational modification]; other site
1042417000497	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1042417000498	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1042417000499	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000500	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000501	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000502	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000503	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000504	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1042417000505	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1042417000506	NAD binding site [chemical binding]; other site
1042417000507	homodimer interface [polypeptide binding]; other site
1042417000508	active site
1042417000509	substrate binding site [chemical binding]; other site
1042417000510	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1042417000511	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1042417000512	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1042417000513	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000514	binding surface
1042417000515	TPR motif; other site
1042417000516	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000517	TPR repeat; Region: TPR_11; pfam13414
1042417000518	TPR motif; other site
1042417000519	binding surface
1042417000520	TPR repeat; Region: TPR_11; pfam13414
1042417000521	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000522	TPR motif; other site
1042417000523	binding surface
1042417000524	Bax inhibitor 1 like; Region: BaxI_1; cl17691
1042417000525	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1042417000526	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1042417000527	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1042417000528	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1042417000529	substrate binding pocket [chemical binding]; other site
1042417000530	chain length determination region; other site
1042417000531	substrate-Mg2+ binding site; other site
1042417000532	catalytic residues [active]
1042417000533	aspartate-rich region 1; other site
1042417000534	active site lid residues [active]
1042417000535	aspartate-rich region 2; other site
1042417000536	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1042417000537	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1042417000538	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
1042417000539	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
1042417000540	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000541	motif II; other site
1042417000542	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417000543	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
1042417000544	Protein of unknown function (DUF1318); Region: DUF1318; cl01547
1042417000545	potential frameshift: common BLAST hit: gi|300870044|ref|YP_003784915.1| TrmA-family RNA methyltransferase
1042417000546	putative hydrolase; Provisional; Region: PRK02113
1042417000547	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1042417000548	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1042417000549	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1042417000550	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1042417000551	active site turn [active]
1042417000552	phosphorylation site [posttranslational modification]
1042417000553	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
1042417000554	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1042417000555	active site
1042417000556	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1042417000557	Phosphoglycerate kinase; Region: PGK; pfam00162
1042417000558	substrate binding site [chemical binding]; other site
1042417000559	hinge regions; other site
1042417000560	ADP binding site [chemical binding]; other site
1042417000561	catalytic site [active]
1042417000562	cytosolic glyceraldehyde 3-phosphate dehydrogenase; Provisional; Region: PTZ00434
1042417000563	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1042417000564	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1042417000565	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1042417000566	Serine hydrolase (FSH1); Region: FSH1; pfam03959
1042417000567	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1042417000568	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
1042417000569	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
1042417000570	methionine sulfoxide reductase B; Provisional; Region: PRK05508
1042417000571	potassium/proton antiporter; Reviewed; Region: PRK05326
1042417000572	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1042417000573	TrkA-C domain; Region: TrkA_C; pfam02080
1042417000574	TrkA-C domain; Region: TrkA_C; pfam02080
1042417000575	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1042417000576	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1042417000577	ring oligomerisation interface [polypeptide binding]; other site
1042417000578	ATP/Mg binding site [chemical binding]; other site
1042417000579	stacking interactions; other site
1042417000580	hinge regions; other site
1042417000581	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417000582	Coenzyme A binding pocket [chemical binding]; other site
1042417000583	potential frameshift: common BLAST hit: gi|300870029|ref|YP_003784900.1| alpha-L-fucosidase
1042417000584	phosphodiesterase; Provisional; Region: PRK12704
1042417000585	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417000586	Zn2+ binding site [ion binding]; other site
1042417000587	Mg2+ binding site [ion binding]; other site
1042417000588	potential frameshift: common BLAST hit: gi|300870027|ref|YP_003784898.1| metallo-dependent phosphatase
1042417000589	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417000590	Zn2+ binding site [ion binding]; other site
1042417000591	Mg2+ binding site [ion binding]; other site
1042417000592	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1042417000593	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1042417000594	HflX GTPase family; Region: HflX; cd01878
1042417000595	G1 box; other site
1042417000596	GTP/Mg2+ binding site [chemical binding]; other site
1042417000597	Switch I region; other site
1042417000598	G2 box; other site
1042417000599	G3 box; other site
1042417000600	Switch II region; other site
1042417000601	G4 box; other site
1042417000602	G5 box; other site
1042417000603	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1042417000604	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1042417000605	dimer interface [polypeptide binding]; other site
1042417000606	motif 1; other site
1042417000607	active site
1042417000608	motif 2; other site
1042417000609	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1042417000610	putative deacylase active site [active]
1042417000611	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1042417000612	active site
1042417000613	motif 3; other site
1042417000614	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1042417000615	anticodon binding site; other site
1042417000616	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417000617	Coenzyme A binding pocket [chemical binding]; other site
1042417000618	Predicted permeases [General function prediction only]; Region: COG0795
1042417000619	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1042417000620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
1042417000621	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
1042417000622	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417000623	active site
1042417000624	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1042417000625	putative trimer interface [polypeptide binding]; other site
1042417000626	putative CoA binding site [chemical binding]; other site
1042417000627	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1042417000628	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1042417000629	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
1042417000630	substrate binding pocket [chemical binding]; other site
1042417000631	dimer interface [polypeptide binding]; other site
1042417000632	inhibitor binding site; inhibition site
1042417000633	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
1042417000634	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1042417000635	B12 binding site [chemical binding]; other site
1042417000636	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
1042417000637	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1042417000638	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1042417000639	FAD binding site [chemical binding]; other site
1042417000640	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417000641	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417000642	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1042417000643	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
1042417000644	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1042417000645	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1042417000646	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1042417000647	active site
1042417000648	catalytic site [active]
1042417000649	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
1042417000650	aconitate hydratase; Validated; Region: PRK07229
1042417000651	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1042417000652	substrate binding site [chemical binding]; other site
1042417000653	ligand binding site [chemical binding]; other site
1042417000654	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1042417000655	substrate binding site [chemical binding]; other site
1042417000656	isocitrate dehydrogenase; Validated; Region: PRK07362
1042417000657	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
1042417000658	citrate synthase; Provisional; Region: PRK14032
1042417000659	Citrate synthase; Region: Citrate_synt; pfam00285
1042417000660	oxalacetate binding site [chemical binding]; other site
1042417000661	citrylCoA binding site [chemical binding]; other site
1042417000662	coenzyme A binding site [chemical binding]; other site
1042417000663	catalytic triad [active]
1042417000664	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1042417000665	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000666	motif II; other site
1042417000667	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1042417000668	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1042417000669	ligand binding site [chemical binding]; other site
1042417000670	NAD binding site [chemical binding]; other site
1042417000671	dimerization interface [polypeptide binding]; other site
1042417000672	catalytic site [active]
1042417000673	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1042417000674	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
1042417000675	homodimer interface [polypeptide binding]; other site
1042417000676	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417000677	catalytic residue [active]
1042417000678	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1042417000679	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
1042417000680	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1042417000681	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1042417000682	putative dimer interface [polypeptide binding]; other site
1042417000683	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1042417000684	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1042417000685	putative dimer interface [polypeptide binding]; other site
1042417000686	potential frameshift: common BLAST hit: gi|296125244|ref|YP_003632496.1| TraB determinant protein
1042417000687	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1042417000688	Transglycosylase; Region: Transgly; pfam00912
1042417000689	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1042417000690	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1042417000691	GAF domain; Region: GAF_3; pfam13492
1042417000692	GAF domain; Region: GAF; pfam01590
1042417000693	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1042417000694	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1042417000695	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417000696	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1042417000697	putative substrate translocation pore; other site
1042417000698	GTPase RsgA; Reviewed; Region: PRK01889
1042417000699	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1042417000700	RNA binding site [nucleotide binding]; other site
1042417000701	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1042417000702	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1042417000703	GTP/Mg2+ binding site [chemical binding]; other site
1042417000704	G4 box; other site
1042417000705	G5 box; other site
1042417000706	G1 box; other site
1042417000707	Switch I region; other site
1042417000708	G2 box; other site
1042417000709	G3 box; other site
1042417000710	Switch II region; other site
1042417000711	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417000712	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417000713	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417000714	META domain; Region: META; pfam03724
1042417000715	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
1042417000716	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1042417000717	Walker A/P-loop; other site
1042417000718	ATP binding site [chemical binding]; other site
1042417000719	Q-loop/lid; other site
1042417000720	ABC transporter signature motif; other site
1042417000721	Walker B; other site
1042417000722	D-loop; other site
1042417000723	H-loop/switch region; other site
1042417000724	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
1042417000725	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
1042417000726	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1042417000727	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1042417000728	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1042417000729	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1042417000730	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1042417000731	FMN binding site [chemical binding]; other site
1042417000732	active site
1042417000733	catalytic residues [active]
1042417000734	substrate binding site [chemical binding]; other site
1042417000735	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1042417000736	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417000737	putative substrate translocation pore; other site
1042417000738	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1042417000739	active site
1042417000740	metal binding site [ion binding]; metal-binding site
1042417000741	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1042417000742	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1042417000743	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1042417000744	potential frameshift: common BLAST hit: gi|300869973|ref|YP_003784844.1| chemotaxis histidine kinase CheA
1042417000745	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1042417000746	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1042417000747	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1042417000748	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000749	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1042417000750	active site
1042417000751	motif I; other site
1042417000752	motif II; other site
1042417000753	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000754	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000755	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1042417000756	active site
1042417000757	motif I; other site
1042417000758	motif II; other site
1042417000759	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417000760	potential frameshift: common BLAST hit: gi|300869965|ref|YP_003784836.1| putative haloacid dehalogenase-like hydrolase
1042417000761	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0718
1042417000762	recombination protein RecR; Reviewed; Region: recR; PRK00076
1042417000763	RecR protein; Region: RecR; pfam02132
1042417000764	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1042417000765	putative active site [active]
1042417000766	putative metal-binding site [ion binding]; other site
1042417000767	tetramer interface [polypeptide binding]; other site
1042417000768	selenocysteine-specific elongation factor SelB; Region: selB; TIGR00475
1042417000769	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1042417000770	G1 box; other site
1042417000771	putative GEF interaction site [polypeptide binding]; other site
1042417000772	GTP/Mg2+ binding site [chemical binding]; other site
1042417000773	Switch I region; other site
1042417000774	G2 box; other site
1042417000775	G3 box; other site
1042417000776	Switch II region; other site
1042417000777	G4 box; other site
1042417000778	G5 box; other site
1042417000779	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1042417000780	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1042417000781	selenocysteine synthase; Provisional; Region: PRK04311
1042417000782	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1042417000783	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1042417000784	anti sigma factor interaction site; other site
1042417000785	regulatory phosphorylation site [posttranslational modification]; other site
1042417000786	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1042417000787	Na binding site [ion binding]; other site
1042417000788	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1042417000789	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1042417000790	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1042417000791	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1042417000792	DNA binding site [nucleotide binding]
1042417000793	active site
1042417000794	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1042417000795	catalytic triad [active]
1042417000796	conserved cis-peptide bond; other site
1042417000797	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1042417000798	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1042417000799	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1042417000800	active site
1042417000801	HIGH motif; other site
1042417000802	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1042417000803	active site
1042417000804	KMSKS motif; other site
1042417000805	Response regulator receiver domain; Region: Response_reg; pfam00072
1042417000806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417000807	active site
1042417000808	phosphorylation site [posttranslational modification]
1042417000809	intermolecular recognition site; other site
1042417000810	dimerization interface [polypeptide binding]; other site
1042417000811	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1042417000812	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1042417000813	substrate binding site [chemical binding]; other site
1042417000814	hexamer interface [polypeptide binding]; other site
1042417000815	metal binding site [ion binding]; metal-binding site
1042417000816	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1042417000817	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1042417000818	dimerization interface [polypeptide binding]; other site
1042417000819	active site
1042417000820	metal binding site [ion binding]; metal-binding site
1042417000821	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1042417000822	dsRNA binding site [nucleotide binding]; other site
1042417000823	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1042417000824	GTP1/OBG; Region: GTP1_OBG; pfam01018
1042417000825	Obg GTPase; Region: Obg; cd01898
1042417000826	G1 box; other site
1042417000827	GTP/Mg2+ binding site [chemical binding]; other site
1042417000828	Switch I region; other site
1042417000829	G2 box; other site
1042417000830	G3 box; other site
1042417000831	Switch II region; other site
1042417000832	G4 box; other site
1042417000833	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
1042417000834	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417000835	FeS/SAM binding site; other site
1042417000836	Putative motility protein; Region: YjfB_motility; pfam14070
1042417000837	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1042417000838	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1042417000839	oligomer interface [polypeptide binding]; other site
1042417000840	active site
1042417000841	metal binding site [ion binding]; metal-binding site
1042417000842	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417000843	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1042417000844	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1042417000845	active site
1042417000846	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417000847	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1042417000848	Walker A/P-loop; other site
1042417000849	ATP binding site [chemical binding]; other site
1042417000850	ABC transporter; Region: ABC_tran; pfam00005
1042417000851	Q-loop/lid; other site
1042417000852	ABC transporter signature motif; other site
1042417000853	Walker B; other site
1042417000854	D-loop; other site
1042417000855	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417000856	H-loop/switch region; other site
1042417000857	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1042417000858	acetylornithine aminotransferase; Provisional; Region: PRK02627
1042417000859	inhibitor-cofactor binding pocket; inhibition site
1042417000860	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417000861	catalytic residue [active]
1042417000862	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
1042417000863	feedback inhibition sensing region; other site
1042417000864	homohexameric interface [polypeptide binding]; other site
1042417000865	nucleotide binding site [chemical binding]; other site
1042417000866	N-acetyl-L-glutamate binding site [chemical binding]; other site
1042417000867	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1042417000868	heterotetramer interface [polypeptide binding]; other site
1042417000869	active site pocket [active]
1042417000870	cleavage site
1042417000871	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1042417000872	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1042417000873	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1042417000874	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1042417000875	potential frameshift: common BLAST hit: gi|300869928|ref|YP_003784799.1| excinuclease ABC subunit A
1042417000876	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
1042417000877	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1042417000878	active site
1042417000879	FMN binding site [chemical binding]; other site
1042417000880	substrate binding site [chemical binding]; other site
1042417000881	putative catalytic residue [active]
1042417000882	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417000883	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417000884	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1042417000885	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417000886	putative substrate translocation pore; other site
1042417000887	Predicted transcriptional regulators [Transcription]; Region: COG1695
1042417000888	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1042417000889	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1042417000890	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1042417000891	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000892	binding surface
1042417000893	TPR motif; other site
1042417000894	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000895	binding surface
1042417000896	TPR motif; other site
1042417000897	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417000898	binding surface
1042417000899	TPR motif; other site
1042417000900	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1042417000901	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417000902	S-adenosylmethionine binding site [chemical binding]; other site
1042417000903	potential frameshift: common BLAST hit: gi|300869922|ref|YP_003784793.1| flavodoxin family protein
1042417000904	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1042417000905	dimerization interface [polypeptide binding]; other site
1042417000906	putative DNA binding site [nucleotide binding]; other site
1042417000907	putative Zn2+ binding site [ion binding]; other site
1042417000908	potential frameshift: common BLAST hit: gi|296127071|ref|YP_003634323.1| permease
1042417000909	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1042417000910	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1042417000911	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1042417000912	Putative N-acetylmannosamine-6-phosphate epimerase; Region: NanE; pfam04131
1042417000913	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
1042417000914	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
1042417000915	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1042417000916	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1042417000917	tetramer interface [polypeptide binding]; other site
1042417000918	heme binding pocket [chemical binding]; other site
1042417000919	NADPH binding site [chemical binding]; other site
1042417000920	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1042417000921	Melibiase; Region: Melibiase; pfam02065
1042417000922	PBP superfamily domain; Region: PBP_like_2; cl17296
1042417000923	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1042417000924	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417000925	dimer interface [polypeptide binding]; other site
1042417000926	conserved gate region; other site
1042417000927	putative PBP binding loops; other site
1042417000928	ABC-ATPase subunit interface; other site
1042417000929	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1042417000930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417000931	dimer interface [polypeptide binding]; other site
1042417000932	conserved gate region; other site
1042417000933	putative PBP binding loops; other site
1042417000934	ABC-ATPase subunit interface; other site
1042417000935	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1042417000936	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1042417000937	Walker A/P-loop; other site
1042417000938	ATP binding site [chemical binding]; other site
1042417000939	Q-loop/lid; other site
1042417000940	ABC transporter signature motif; other site
1042417000941	Walker B; other site
1042417000942	D-loop; other site
1042417000943	H-loop/switch region; other site
1042417000944	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1042417000945	PhoU domain; Region: PhoU; pfam01895
1042417000946	PhoU domain; Region: PhoU; pfam01895
1042417000947	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1042417000948	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1042417000949	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
1042417000950	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1042417000951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3330
1042417000952	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1042417000953	active site residue [active]
1042417000954	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417000955	AAA domain; Region: AAA_21; pfam13304
1042417000956	Walker A/P-loop; other site
1042417000957	ATP binding site [chemical binding]; other site
1042417000958	AAA ATPase domain; Region: AAA_15; pfam13175
1042417000959	aspartate aminotransferase; Provisional; Region: PRK07568
1042417000960	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1042417000961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417000962	homodimer interface [polypeptide binding]; other site
1042417000963	catalytic residue [active]
1042417000964	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1042417000965	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1042417000966	potential frameshift: common BLAST hit: gi|300869897|ref|YP_003784768.1| carbamoyl phosphate synthase large subunit
1042417000967	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1042417000968	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1042417000969	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1042417000970	catalytic site [active]
1042417000971	subunit interface [polypeptide binding]; other site
1042417000972	potential frameshift: common BLAST hit: gi|300869895|ref|YP_003784766.1| putative regulator protein BtrU
1042417000973	threonine synthase; Reviewed; Region: PRK06721
1042417000974	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1042417000975	homodimer interface [polypeptide binding]; other site
1042417000976	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417000977	catalytic residue [active]
1042417000978	homoserine kinase; Provisional; Region: PRK01212
1042417000979	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1042417000980	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1042417000981	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1042417000982	NAD binding site [chemical binding]; other site
1042417000983	sugar binding site [chemical binding]; other site
1042417000984	divalent metal binding site [ion binding]; other site
1042417000985	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1042417000986	dimer interface [polypeptide binding]; other site
1042417000987	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1042417000988	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1042417000989	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1042417000990	active site turn [active]
1042417000991	phosphorylation site [posttranslational modification]
1042417000992	alpha-galactosidase; Provisional; Region: PRK15076
1042417000993	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1042417000994	NAD(P) binding site [chemical binding]; other site
1042417000995	LDH/MDH dimer interface [polypeptide binding]; other site
1042417000996	substrate binding site [chemical binding]; other site
1042417000997	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1042417000998	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1042417000999	ligand binding site [chemical binding]; other site
1042417001000	dimerization interface [polypeptide binding]; other site
1042417001001	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1042417001002	N-terminal catalytic domain of 4-alpha-glucanotransferase; glycoside hydrolase family 57 (GH57); Region: GH57N_TLGT_like; cd10793
1042417001003	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
1042417001004	active site
1042417001005	catalytic site [active]
1042417001006	homodimer interface [polypeptide binding]; other site
1042417001007	Lid 1; other site
1042417001008	Domain of unknown function (DUF1925); Region: DUF1925; pfam09094
1042417001009	Domain of unknown function (DUF1926); Region: DUF1926; pfam09095
1042417001010	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1042417001011	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1042417001012	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1042417001013	trimerization site [polypeptide binding]; other site
1042417001014	active site
1042417001015	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1042417001016	NifU-like domain; Region: NifU; pfam01106
1042417001017	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1042417001018	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1042417001019	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1042417001020	catalytic residue [active]
1042417001021	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1042417001022	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1042417001023	dimer interface [polypeptide binding]; other site
1042417001024	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417001025	catalytic residue [active]
1042417001026	serine O-acetyltransferase; Region: cysE; TIGR01172
1042417001027	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1042417001028	trimer interface [polypeptide binding]; other site
1042417001029	active site
1042417001030	substrate binding site [chemical binding]; other site
1042417001031	CoA binding site [chemical binding]; other site
1042417001032	elongation factor Ts; Provisional; Region: tsf; PRK09377
1042417001033	UBA/TS-N domain; Region: UBA; pfam00627
1042417001034	Elongation factor TS; Region: EF_TS; pfam00889
1042417001035	Elongation factor TS; Region: EF_TS; pfam00889
1042417001036	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1042417001037	rRNA interaction site [nucleotide binding]; other site
1042417001038	S8 interaction site; other site
1042417001039	putative laminin-1 binding site; other site
1042417001040	potential frameshift: common BLAST hit: gi|300869879|ref|YP_003784750.1| glucosamine--fructose-6-phosphate aminotransferase
1042417001041	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1042417001042	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1042417001043	K+-dependent Na+/Ca+ exchanger related-protein; Region: TIGR00367
1042417001044	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1042417001045	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1042417001046	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1042417001047	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1042417001048	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417001049	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1042417001050	Walker A/P-loop; other site
1042417001051	ATP binding site [chemical binding]; other site
1042417001052	Q-loop/lid; other site
1042417001053	ABC transporter signature motif; other site
1042417001054	Walker B; other site
1042417001055	D-loop; other site
1042417001056	H-loop/switch region; other site
1042417001057	Septum formation initiator; Region: DivIC; cl17659
1042417001058	Curli production assembly/transport component CsgG; Region: CsgG; cl17434
1042417001059	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1042417001060	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1042417001061	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1042417001062	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1042417001063	nucleotide binding region [chemical binding]; other site
1042417001064	SEC-C motif; Region: SEC-C; pfam02810
1042417001065	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1042417001066	EamA-like transporter family; Region: EamA; pfam00892
1042417001067	ScpA/B protein; Region: ScpA_ScpB; cl00598
1042417001068	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001069	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001070	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001071	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001072	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001073	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417001074	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1042417001075	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1042417001076	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
1042417001077	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1042417001078	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1042417001079	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1042417001080	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1042417001081	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1042417001082	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1042417001083	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1042417001084	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1042417001085	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1042417001086	flagellin; Provisional; Region: PRK12804
1042417001087	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1042417001088	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1042417001089	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001090	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001091	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001092	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001093	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001094	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001095	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001096	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001097	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001098	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001099	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001100	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417001101	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417001102	Cache domain; Region: Cache_1; pfam02743
1042417001103	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417001104	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417001105	dimer interface [polypeptide binding]; other site
1042417001106	putative CheW interface [polypeptide binding]; other site
1042417001107	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
1042417001108	putative homodimer interface [polypeptide binding]; other site
1042417001109	putative active site pocket [active]
1042417001110	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
1042417001111	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1042417001112	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1042417001113	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1042417001114	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417001115	ATP binding site [chemical binding]; other site
1042417001116	putative Mg++ binding site [ion binding]; other site
1042417001117	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417001118	nucleotide binding region [chemical binding]; other site
1042417001119	ATP-binding site [chemical binding]; other site
1042417001120	TPR repeat; Region: TPR_11; pfam13414
1042417001121	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001122	binding surface
1042417001123	TPR motif; other site
1042417001124	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417001125	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
1042417001126	potential frameshift: common BLAST hit: gi|300869838|ref|YP_003784709.1| family 5 extracellular solute-binding protein
1042417001127	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1042417001128	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1042417001129	catalytic triad [active]
1042417001130	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1042417001131	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417001132	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1042417001133	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1042417001134	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1042417001135	ABC transporter; Region: ABC_tran_2; pfam12848
1042417001136	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1042417001137	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1042417001138	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1042417001139	active site
1042417001140	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1042417001141	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1042417001142	metal ion-dependent adhesion site (MIDAS); other site
1042417001143	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417001144	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001145	TPR motif; other site
1042417001146	binding surface
1042417001147	Oxygen tolerance; Region: BatD; pfam13584
1042417001148	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417001149	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1042417001150	ABC1 family; Region: ABC1; cl17513
1042417001151	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1042417001152	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1042417001153	PYR/PP interface [polypeptide binding]; other site
1042417001154	dimer interface [polypeptide binding]; other site
1042417001155	TPP binding site [chemical binding]; other site
1042417001156	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1042417001157	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1042417001158	TPP-binding site [chemical binding]; other site
1042417001159	dimer interface [polypeptide binding]; other site
1042417001160	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1042417001161	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1042417001162	putative valine binding site [chemical binding]; other site
1042417001163	dimer interface [polypeptide binding]; other site
1042417001164	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1042417001165	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1042417001166	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1042417001167	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1042417001168	2-isopropylmalate synthase; Validated; Region: PRK00915
1042417001169	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1042417001170	active site
1042417001171	metal binding site [ion binding]; metal-binding site
1042417001172	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1042417001173	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1042417001174	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1042417001175	substrate binding site [chemical binding]; other site
1042417001176	ligand binding site [chemical binding]; other site
1042417001177	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
1042417001178	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1042417001179	substrate binding site [chemical binding]; other site
1042417001180	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1042417001181	tartrate dehydrogenase; Region: TTC; TIGR02089
1042417001182	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1042417001183	potential frameshift: common BLAST hit: gi|300869818|ref|YP_003784689.1| acyl-ACP thioesterase
1042417001184	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1042417001185	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001186	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001187	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1042417001188	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1042417001189	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1042417001190	catalytic residues [active]
1042417001191	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1042417001192	active site residue [active]
1042417001193	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1042417001194	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
1042417001195	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1042417001196	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417001197	S-adenosylmethionine binding site [chemical binding]; other site
1042417001198	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1042417001199	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1042417001200	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1042417001201	potential frameshift: common BLAST hit: gi|300869809|ref|YP_003784680.1| type-I restriction endonuclease R subunit HsdR
1042417001202	Predicted periplasmic protein (DUF2271); Region: DUF2271; cl17856
1042417001203	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001204	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001205	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001206	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001207	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001208	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
1042417001209	hydrophobic ligand binding site; other site
1042417001210	MOSC domain; Region: MOSC; pfam03473
1042417001211	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1042417001212	MPT binding site; other site
1042417001213	trimer interface [polypeptide binding]; other site
1042417001214	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1042417001215	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1042417001216	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417001217	dimer interface [polypeptide binding]; other site
1042417001218	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1042417001219	conserved gate region; other site
1042417001220	putative PBP binding loops; other site
1042417001221	ABC-ATPase subunit interface; other site
1042417001222	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1042417001223	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417001224	Walker A/P-loop; other site
1042417001225	ATP binding site [chemical binding]; other site
1042417001226	Q-loop/lid; other site
1042417001227	ABC transporter signature motif; other site
1042417001228	Walker B; other site
1042417001229	D-loop; other site
1042417001230	H-loop/switch region; other site
1042417001231	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1042417001232	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1042417001233	dimer interface [polypeptide binding]; other site
1042417001234	putative functional site; other site
1042417001235	putative MPT binding site; other site
1042417001236	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1042417001237	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417001238	FeS/SAM binding site; other site
1042417001239	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1042417001240	MoaC family. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor...; Region: MoaC; cd00528
1042417001241	trimer interface [polypeptide binding]; other site
1042417001242	dimer interface [polypeptide binding]; other site
1042417001243	putative active site [active]
1042417001244	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1042417001245	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1042417001246	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1042417001247	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1042417001248	active site
1042417001249	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
1042417001250	Response regulator receiver domain; Region: Response_reg; pfam00072
1042417001251	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417001252	active site
1042417001253	phosphorylation site [posttranslational modification]
1042417001254	intermolecular recognition site; other site
1042417001255	dimerization interface [polypeptide binding]; other site
1042417001256	Homeodomain-like domain; Region: HTH_23; cl17451
1042417001257	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1042417001258	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1042417001259	active site
1042417001260	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1042417001261	substrate binding site [chemical binding]; other site
1042417001262	catalytic residues [active]
1042417001263	dimer interface [polypeptide binding]; other site
1042417001264	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1042417001265	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
1042417001266	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1042417001267	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1042417001268	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417001269	active site
1042417001270	motif I; other site
1042417001271	motif II; other site
1042417001272	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1042417001273	OstA-like protein; Region: OstA_2; pfam13100
1042417001274	OstA-like protein; Region: OstA; cl00844
1042417001275	OstA-like protein; Region: OstA; cl00844
1042417001276	OstA-like protein; Region: OstA; cl00844
1042417001277	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1042417001278	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1042417001279	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1042417001280	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1042417001281	catalytic residue [active]
1042417001282	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1042417001283	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1042417001284	DNA binding site [nucleotide binding]
1042417001285	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1042417001286	ligand binding site [chemical binding]; other site
1042417001287	dimerization interface [polypeptide binding]; other site
1042417001288	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1042417001289	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1042417001290	dimer interface [polypeptide binding]; other site
1042417001291	active site
1042417001292	metal binding site [ion binding]; metal-binding site
1042417001293	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1042417001294	intersubunit interface [polypeptide binding]; other site
1042417001295	active site
1042417001296	Zn2+ binding site [ion binding]; other site
1042417001297	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1042417001298	N- and C-terminal domain interface [polypeptide binding]; other site
1042417001299	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1042417001300	active site
1042417001301	putative catalytic site [active]
1042417001302	metal binding site [ion binding]; metal-binding site
1042417001303	ATP binding site [chemical binding]; other site
1042417001304	carbohydrate binding site [chemical binding]; other site
1042417001305	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1042417001306	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1042417001307	Walker A/P-loop; other site
1042417001308	ATP binding site [chemical binding]; other site
1042417001309	Q-loop/lid; other site
1042417001310	ABC transporter signature motif; other site
1042417001311	Walker B; other site
1042417001312	D-loop; other site
1042417001313	H-loop/switch region; other site
1042417001314	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1042417001315	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417001316	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1042417001317	TM-ABC transporter signature motif; other site
1042417001318	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1042417001319	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1042417001320	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1042417001321	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
1042417001322	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1042417001323	trimer interface [polypeptide binding]; other site
1042417001324	substrate binding site [chemical binding]; other site
1042417001325	Mn binding site [ion binding]; other site
1042417001326	RbsD / FucU transport protein family; Region: RbsD_FucU; pfam05025
1042417001327	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1042417001328	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1042417001329	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1042417001330	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1042417001331	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1042417001332	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1042417001333	galactokinase; Provisional; Region: PRK05322
1042417001334	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1042417001335	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1042417001336	potential frameshift: common BLAST hit: gi|300869767|ref|YP_003784638.1| peptide chain release factor RF-2
1042417001337	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
1042417001338	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
1042417001339	Ankyrin repeat; Region: Ank; pfam00023
1042417001340	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001341	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001342	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001343	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1042417001344	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1042417001345	ligand binding site [chemical binding]; other site
1042417001346	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1042417001347	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1042417001348	ligand binding site [chemical binding]; other site
1042417001349	flexible hinge region; other site
1042417001350	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1042417001351	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1042417001352	RNA binding surface [nucleotide binding]; other site
1042417001353	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1042417001354	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417001355	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1042417001356	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1042417001357	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1042417001358	dimer interface [polypeptide binding]; other site
1042417001359	active site
1042417001360	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1042417001361	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1042417001362	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1042417001363	putative active site [active]
1042417001364	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001365	TPR motif; other site
1042417001366	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417001367	binding surface
1042417001368	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417001369	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
1042417001370	Carbon starvation protein CstA; Region: CstA; pfam02554
1042417001371	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1042417001372	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1042417001373	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1042417001374	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1042417001375	active site
1042417001376	(T/H)XGH motif; other site
1042417001377	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
1042417001378	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1042417001379	active site
1042417001380	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1042417001381	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1042417001382	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1042417001383	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1042417001384	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
1042417001385	active site
1042417001386	substrate binding site [chemical binding]; other site
1042417001387	metal binding site [ion binding]; metal-binding site
1042417001388	potential frameshift: common BLAST hit: gi|300869745|ref|YP_003784616.1| allergen V5/Tpx-1-like protein
1042417001389	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1042417001390	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1042417001391	SirA-like protein; Region: SirA; pfam01206
1042417001392	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
1042417001393	CPxP  motif; other site
1042417001394	DsrE/DsrF-like family; Region: DrsE; pfam02635
1042417001395	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1042417001396	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1042417001397	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1042417001398	catalytic residue [active]
1042417001399	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1042417001400	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1042417001401	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1042417001402	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
1042417001403	SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339
1042417001404	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1042417001405	active site
1042417001406	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1042417001407	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1042417001408	active site
1042417001409	dimer interface [polypeptide binding]; other site
1042417001410	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1042417001411	CoenzymeA binding site [chemical binding]; other site
1042417001412	subunit interaction site [polypeptide binding]; other site
1042417001413	PHB binding site; other site
1042417001414	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1042417001415	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1042417001416	Response regulator receiver domain; Region: Response_reg; pfam00072
1042417001417	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417001418	active site
1042417001419	phosphorylation site [posttranslational modification]
1042417001420	intermolecular recognition site; other site
1042417001421	dimerization interface [polypeptide binding]; other site
1042417001422	ADP-glucose phosphorylase; Region: PLN02643
1042417001423	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
1042417001424	nucleotide binding site/active site [active]
1042417001425	HIT family signature motif; other site
1042417001426	catalytic residue [active]
1042417001427	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
1042417001428	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417001429	S-adenosylmethionine binding site [chemical binding]; other site
1042417001430	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1042417001431	putative CoA binding site [chemical binding]; other site
1042417001432	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
1042417001433	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
1042417001434	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1042417001435	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417001436	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1042417001437	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1042417001438	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1042417001439	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
1042417001440	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1042417001441	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1042417001442	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cl00540
1042417001443	tetramerization interface [polypeptide binding]; other site
1042417001444	active site
1042417001445	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1042417001446	SirA-like protein; Region: SirA; pfam01206
1042417001447	CPxP  motif; other site
1042417001448	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1042417001449	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1042417001450	putative catalytic cysteine [active]
1042417001451	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
1042417001452	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001453	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001454	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001455	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001456	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1042417001457	dimerization domain swap beta strand [polypeptide binding]; other site
1042417001458	regulatory protein interface [polypeptide binding]; other site
1042417001459	active site
1042417001460	regulatory phosphorylation site [posttranslational modification]; other site
1042417001461	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1042417001462	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1042417001463	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1042417001464	trimer interface [polypeptide binding]; other site
1042417001465	active site
1042417001466	potential frameshift: common BLAST hit: gi|300869715|ref|YP_003784586.1| acetate kinase
1042417001467	META domain; Region: META; pfam03724
1042417001468	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1042417001469	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1042417001470	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1042417001471	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417001472	S-adenosylmethionine binding site [chemical binding]; other site
1042417001473	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1042417001474	Part of AAA domain; Region: AAA_19; pfam13245
1042417001475	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1042417001476	Family description; Region: UvrD_C_2; pfam13538
1042417001477	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1042417001478	Acylphosphatase; Region: Acylphosphatase; pfam00708
1042417001479	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001480	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001481	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001482	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1042417001483	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001484	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001485	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001486	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1042417001487	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417001488	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417001489	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1042417001490	MgtC family; Region: MgtC; pfam02308
1042417001491	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001492	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001493	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001494	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001495	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001496	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1042417001497	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1042417001498	active site
1042417001499	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
1042417001500	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1042417001501	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1042417001502	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1042417001503	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1042417001504	TPP-binding site; other site
1042417001505	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1042417001506	PYR/PP interface [polypeptide binding]; other site
1042417001507	dimer interface [polypeptide binding]; other site
1042417001508	TPP binding site [chemical binding]; other site
1042417001509	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1042417001510	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1042417001511	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1042417001512	metal binding site [ion binding]; metal-binding site
1042417001513	dimer interface [polypeptide binding]; other site
1042417001514	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1042417001515	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1042417001516	dimer interface [polypeptide binding]; other site
1042417001517	active site
1042417001518	catalytic residue [active]
1042417001519	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1042417001520	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1042417001521	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1042417001522	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
1042417001523	Amidinotransferase; Region: Amidinotransf; cl12043
1042417001524	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417001525	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1042417001526	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1042417001527	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417001528	Coenzyme A binding pocket [chemical binding]; other site
1042417001529	flagellar hook-associated protein FlgL; Validated; Region: PRK06663
1042417001530	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1042417001531	FliW protein; Region: FliW; cl00740
1042417001532	Global regulator protein family; Region: CsrA; pfam02599
1042417001533	glutamate racemase; Provisional; Region: PRK00865
1042417001534	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
1042417001535	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1042417001536	active site
1042417001537	catalytic residues [active]
1042417001538	metal binding site [ion binding]; metal-binding site
1042417001539	homodimer binding site [polypeptide binding]; other site
1042417001540	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
1042417001541	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1042417001542	carboxyltransferase (CT) interaction site; other site
1042417001543	biotinylation site [posttranslational modification]; other site
1042417001544	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
1042417001545	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1042417001546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417001547	putative substrate translocation pore; other site
1042417001548	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1042417001549	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
1042417001550	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
1042417001551	4Fe-4S binding domain; Region: Fer4; pfam00037
1042417001552	4Fe-4S binding domain; Region: Fer4; pfam00037
1042417001553	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
1042417001554	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1042417001555	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1042417001556	hexamer interface [polypeptide binding]; other site
1042417001557	ligand binding site [chemical binding]; other site
1042417001558	putative active site [active]
1042417001559	NAD(P) binding site [chemical binding]; other site
1042417001560	potential frameshift: common BLAST hit: gi|300869672|ref|YP_003784543.1| magnesium transporter
1042417001561	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001562	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001563	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001564	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001565	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001566	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001567	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001568	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001569	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001570	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001571	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001572	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001573	potential frameshift: common BLAST hit: gi|300869670|ref|YP_003784541.1| drug metabolite transporter permease
1042417001574	flagellar hook-associated protein FliD; Validated; Region: fliD; PRK06664
1042417001575	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1042417001576	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1042417001577	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1042417001578	non-specific DNA binding site [nucleotide binding]; other site
1042417001579	salt bridge; other site
1042417001580	sequence-specific DNA binding site [nucleotide binding]; other site
1042417001581	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1042417001582	MPN+ (JAMM) motif; other site
1042417001583	Zinc-binding site [ion binding]; other site
1042417001584	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1042417001585	dimer interface [polypeptide binding]; other site
1042417001586	pyridoxal binding site [chemical binding]; other site
1042417001587	ATP binding site [chemical binding]; other site
1042417001588	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001589	binding surface
1042417001590	TPR motif; other site
1042417001591	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001592	binding surface
1042417001593	TPR motif; other site
1042417001594	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1042417001595	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1042417001596	chaperone protein DnaJ; Provisional; Region: PRK10767
1042417001597	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1042417001598	HSP70 interaction site [polypeptide binding]; other site
1042417001599	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1042417001600	substrate binding site [polypeptide binding]; other site
1042417001601	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1042417001602	Zn binding sites [ion binding]; other site
1042417001603	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1042417001604	dimer interface [polypeptide binding]; other site
1042417001605	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1042417001606	HSP70 interaction site [polypeptide binding]; other site
1042417001607	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1042417001608	META domain; Region: META; cl01245
1042417001609	META domain; Region: META; pfam03724
1042417001610	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417001611	peptide binding site [polypeptide binding]; other site
1042417001612	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1042417001613	potential frameshift: common BLAST hit: gi|296126696|ref|YP_003633948.1| Lipoprotein LpqB, GerMN domain protein
1042417001614	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1042417001615	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1042417001616	G-X-X-G motif; other site
1042417001617	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1042417001618	RxxxH motif; other site
1042417001619	membrane protein insertase; Provisional; Region: PRK01318
1042417001620	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1042417001621	Haemolytic domain; Region: Haemolytic; pfam01809
1042417001622	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1042417001623	Domain of unknown function (DUF4416); Region: DUF4416; pfam14385
1042417001624	potential frameshift: common BLAST hit: gi|300869646|ref|YP_003784517.1| methyl-accepting chemotaxis protein B
1042417001625	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
1042417001626	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1042417001627	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1042417001628	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1042417001629	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1042417001630	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1042417001631	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417001632	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1042417001633	FeS/SAM binding site; other site
1042417001634	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
1042417001635	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1042417001636	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1042417001637	dimer interface [polypeptide binding]; other site
1042417001638	putative anticodon binding site; other site
1042417001639	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1042417001640	motif 1; other site
1042417001641	active site
1042417001642	motif 2; other site
1042417001643	motif 3; other site
1042417001644	Uncharacterized protein conserved in bacteria (DUF2262); Region: DUF2262; pfam10020
1042417001645	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
1042417001646	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1042417001647	active site
1042417001648	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1042417001649	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1042417001650	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417001651	Walker A/P-loop; other site
1042417001652	ATP binding site [chemical binding]; other site
1042417001653	Q-loop/lid; other site
1042417001654	ABC transporter signature motif; other site
1042417001655	Walker B; other site
1042417001656	D-loop; other site
1042417001657	H-loop/switch region; other site
1042417001658	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1042417001659	active site
1042417001660	dimerization interface [polypeptide binding]; other site
1042417001661	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1042417001662	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1042417001663	active site
1042417001664	FMN binding site [chemical binding]; other site
1042417001665	substrate binding site [chemical binding]; other site
1042417001666	homotetramer interface [polypeptide binding]; other site
1042417001667	catalytic residue [active]
1042417001668	Cache domain; Region: Cache_1; pfam02743
1042417001669	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417001670	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417001671	dimer interface [polypeptide binding]; other site
1042417001672	putative CheW interface [polypeptide binding]; other site
1042417001673	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001674	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001675	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001676	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001677	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001678	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001679	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001680	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001681	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001682	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001683	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1042417001684	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1042417001685	Walker A/P-loop; other site
1042417001686	ATP binding site [chemical binding]; other site
1042417001687	Q-loop/lid; other site
1042417001688	ABC transporter signature motif; other site
1042417001689	Walker B; other site
1042417001690	D-loop; other site
1042417001691	H-loop/switch region; other site
1042417001692	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1042417001693	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1042417001694	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1042417001695	Walker A/P-loop; other site
1042417001696	ATP binding site [chemical binding]; other site
1042417001697	Q-loop/lid; other site
1042417001698	ABC transporter signature motif; other site
1042417001699	Walker B; other site
1042417001700	D-loop; other site
1042417001701	H-loop/switch region; other site
1042417001702	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1042417001703	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1042417001704	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1042417001705	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417001706	catalytic residue [active]
1042417001707	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417001708	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417001709	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417001710	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1042417001711	TM-ABC transporter signature motif; other site
1042417001712	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1042417001713	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417001714	Walker A/P-loop; other site
1042417001715	ATP binding site [chemical binding]; other site
1042417001716	Q-loop/lid; other site
1042417001717	ABC transporter signature motif; other site
1042417001718	Walker B; other site
1042417001719	D-loop; other site
1042417001720	H-loop/switch region; other site
1042417001721	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1042417001722	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1042417001723	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1042417001724	short chain dehydrogenase; Provisional; Region: PRK06114
1042417001725	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1042417001726	NAD(P) binding site [chemical binding]; other site
1042417001727	active site
1042417001728	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1042417001729	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1042417001730	inhibitor binding site; inhibition site
1042417001731	catalytic Zn binding site [ion binding]; other site
1042417001732	structural Zn binding site [ion binding]; other site
1042417001733	NADP binding site [chemical binding]; other site
1042417001734	tetramer interface [polypeptide binding]; other site
1042417001735	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1042417001736	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1042417001737	nucleotide binding site [chemical binding]; other site
1042417001738	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1042417001739	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1042417001740	nucleotide binding site [chemical binding]; other site
1042417001741	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1042417001742	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1042417001743	nucleotide binding site [chemical binding]; other site
1042417001744	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001745	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001746	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417001747	potential frameshift: common BLAST hit: gi|300871915|ref|YP_003786788.1| putative GntR family transcriptional regulator
1042417001748	potential frameshift: common BLAST hit: gi|300871914|ref|YP_003786787.1| aminopeptidase
1042417001749	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1042417001750	adenylate kinase; Reviewed; Region: adk; PRK00279
1042417001751	AMP-binding site [chemical binding]; other site
1042417001752	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1042417001753	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1042417001754	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1042417001755	NADP binding site [chemical binding]; other site
1042417001756	homopentamer interface [polypeptide binding]; other site
1042417001757	substrate binding site [chemical binding]; other site
1042417001758	active site
1042417001759	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1042417001760	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1042417001761	active site
1042417001762	homodimer interface [polypeptide binding]; other site
1042417001763	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1042417001764	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK02862
1042417001765	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1042417001766	ligand binding site; other site
1042417001767	oligomer interface; other site
1042417001768	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417001769	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1042417001770	dimer interface [polypeptide binding]; other site
1042417001771	N-terminal domain interface [polypeptide binding]; other site
1042417001772	sulfate 1 binding site; other site
1042417001773	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1042417001774	active site residue [active]
1042417001775	potential frameshift: common BLAST hit: gi|300871901|ref|YP_003786774.1| DNA polymerase I
1042417001776	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1042417001777	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1042417001778	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417001779	TPR motif; other site
1042417001780	TPR repeat; Region: TPR_11; pfam13414
1042417001781	binding surface
1042417001782	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1042417001783	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1042417001784	metal binding site [ion binding]; metal-binding site
1042417001785	active site
1042417001786	I-site; other site
1042417001787	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
1042417001788	GDP-Fucose binding site [chemical binding]; other site
1042417001789	Predicted membrane protein [Function unknown]; Region: COG2364
1042417001790	potential frameshift: common BLAST hit: gi|300871895|ref|YP_003786768.1| alpha-2-macroglobulin domain-containing protein
1042417001791	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1042417001792	GIY-YIG motif/motif A; other site
1042417001793	putative active site [active]
1042417001794	putative metal binding site [ion binding]; other site
1042417001795	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417001796	active site
1042417001797	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
1042417001798	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1042417001799	RNA binding site [nucleotide binding]; other site
1042417001800	active site
1042417001801	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1042417001802	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1042417001803	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1042417001804	active site
1042417001805	HIGH motif; other site
1042417001806	dimer interface [polypeptide binding]; other site
1042417001807	KMSKS motif; other site
1042417001808	PSP1 C-terminal conserved region; Region: PSP1; cl00770
1042417001809	NAD synthetase; Provisional; Region: PRK13981
1042417001810	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1042417001811	multimer interface [polypeptide binding]; other site
1042417001812	active site
1042417001813	catalytic triad [active]
1042417001814	protein interface 1 [polypeptide binding]; other site
1042417001815	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1042417001816	Ligand Binding Site [chemical binding]; other site
1042417001817	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; cl17869
1042417001818	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1042417001819	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1042417001820	catalytic site [active]
1042417001821	G-X2-G-X-G-K; other site
1042417001822	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1042417001823	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1042417001824	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1042417001825	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1042417001826	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1042417001827	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1042417001828	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1042417001829	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1042417001830	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1042417001831	Permease; Region: Permease; pfam02405
1042417001832	replicative DNA helicase; Region: DnaB; TIGR00665
1042417001833	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1042417001834	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1042417001835	Walker A motif; other site
1042417001836	ATP binding site [chemical binding]; other site
1042417001837	Walker B motif; other site
1042417001838	DNA binding loops [nucleotide binding]
1042417001839	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1042417001840	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1042417001841	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1042417001842	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1042417001843	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417001844	PQQ-like domain; Region: PQQ_2; pfam13360
1042417001845	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1042417001846	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417001847	potential frameshift: common BLAST hit: gi|300871872|ref|YP_003786745.1| TPR domain-containing protein
1042417001848	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1042417001849	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1042417001850	P-loop; other site
1042417001851	Magnesium ion binding site [ion binding]; other site
1042417001852	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1042417001853	Magnesium ion binding site [ion binding]; other site
1042417001854	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1042417001855	ParB-like nuclease domain; Region: ParB; smart00470
1042417001856	Domain of unknown function (DUF4384); Region: DUF4384; pfam14326
1042417001857	Cache domain; Region: Cache_1; pfam02743
1042417001858	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417001859	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417001860	dimer interface [polypeptide binding]; other site
1042417001861	putative CheW interface [polypeptide binding]; other site
1042417001862	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1042417001863	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1042417001864	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1042417001865	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1042417001866	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1042417001867	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1042417001868	dimerization interface [polypeptide binding]; other site
1042417001869	putative DNA binding site [nucleotide binding]; other site
1042417001870	putative Zn2+ binding site [ion binding]; other site
1042417001871	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1042417001872	Na2 binding site [ion binding]; other site
1042417001873	putative substrate binding site 1 [chemical binding]; other site
1042417001874	Na binding site 1 [ion binding]; other site
1042417001875	putative substrate binding site 2 [chemical binding]; other site
1042417001876	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1042417001877	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1042417001878	Glycoprotease family; Region: Peptidase_M22; pfam00814
1042417001879	Cache domain; Region: Cache_1; pfam02743
1042417001880	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417001881	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417001882	dimer interface [polypeptide binding]; other site
1042417001883	putative CheW interface [polypeptide binding]; other site
1042417001884	tRNA 2-selenouridine synthase; Region: tRNA_sel_U_synt; TIGR03167
1042417001885	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1042417001886	active site residue [active]
1042417001887	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417001888	S-adenosylmethionine binding site [chemical binding]; other site
1042417001889	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1042417001890	oligomerisation interface [polypeptide binding]; other site
1042417001891	mobile loop; other site
1042417001892	roof hairpin; other site
1042417001893	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
1042417001894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417001895	Walker A/P-loop; other site
1042417001896	ATP binding site [chemical binding]; other site
1042417001897	Q-loop/lid; other site
1042417001898	ABC transporter signature motif; other site
1042417001899	Walker B; other site
1042417001900	D-loop; other site
1042417001901	H-loop/switch region; other site
1042417001902	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
1042417001903	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417001904	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417001905	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417001906	TM2 domain; Region: TM2; pfam05154
1042417001907	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1042417001908	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1042417001909	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1042417001910	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1042417001911	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1042417001912	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1042417001913	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1042417001914	NAD binding site [chemical binding]; other site
1042417001915	dimer interface [polypeptide binding]; other site
1042417001916	substrate binding site [chemical binding]; other site
1042417001917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417001918	dimer interface [polypeptide binding]; other site
1042417001919	conserved gate region; other site
1042417001920	ABC-ATPase subunit interface; other site
1042417001921	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1042417001922	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1042417001923	Walker A/P-loop; other site
1042417001924	ATP binding site [chemical binding]; other site
1042417001925	Q-loop/lid; other site
1042417001926	ABC transporter signature motif; other site
1042417001927	Walker B; other site
1042417001928	D-loop; other site
1042417001929	H-loop/switch region; other site
1042417001930	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1042417001931	potential frameshift: common BLAST hit: gi|300871846|ref|YP_003786719.1| DNA-directed RNA polymerase omega subunit family protein-like protein
1042417001932	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1042417001933	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417001934	Walker A/P-loop; other site
1042417001935	ATP binding site [chemical binding]; other site
1042417001936	Q-loop/lid; other site
1042417001937	ABC transporter signature motif; other site
1042417001938	Walker B; other site
1042417001939	D-loop; other site
1042417001940	H-loop/switch region; other site
1042417001941	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1042417001942	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1042417001943	ABC-ATPase subunit  interface; other site
1042417001944	dimer interface [polypeptide binding]; other site
1042417001945	putative PBP binding regions; other site
1042417001946	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1042417001947	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1042417001948	intersubunit interface [polypeptide binding]; other site
1042417001949	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1042417001950	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1042417001951	RNA binding site [nucleotide binding]; other site
1042417001952	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1042417001953	RNA binding site [nucleotide binding]; other site
1042417001954	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1042417001955	RNA binding site [nucleotide binding]; other site
1042417001956	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1042417001957	RNA binding site [nucleotide binding]; other site
1042417001958	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1042417001959	RNA binding site [nucleotide binding]; other site
1042417001960	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1042417001961	RNA binding site [nucleotide binding]; other site
1042417001962	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1042417001963	cytidylate kinase; Provisional; Region: cmk; PRK00023
1042417001964	CMP-binding site; other site
1042417001965	The sites determining sugar specificity; other site
1042417001966	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1042417001967	active site
1042417001968	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1042417001969	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
1042417001970	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1042417001971	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1042417001972	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417001973	DNA binding residues [nucleotide binding]
1042417001974	Glycerol dehydrogenase-like; Region: GlyDH-like2; cd08171
1042417001975	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1042417001976	putative active site [active]
1042417001977	metal binding site [ion binding]; metal-binding site
1042417001978	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1042417001979	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1042417001980	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1042417001981	metal binding site [ion binding]; metal-binding site
1042417001982	active site
1042417001983	I-site; other site
1042417001984	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1042417001985	DNA methylase; Region: N6_N4_Mtase; cl17433
1042417001986	GMP synthase; Reviewed; Region: guaA; PRK00074
1042417001987	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1042417001988	AMP/PPi binding site [chemical binding]; other site
1042417001989	candidate oxyanion hole; other site
1042417001990	catalytic triad [active]
1042417001991	potential glutamine specificity residues [chemical binding]; other site
1042417001992	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1042417001993	ATP Binding subdomain [chemical binding]; other site
1042417001994	Ligand Binding sites [chemical binding]; other site
1042417001995	Dimerization subdomain; other site
1042417001996	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1042417001997	Phosphotransferase enzyme family; Region: APH; pfam01636
1042417001998	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1042417001999	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1042417002000	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1042417002001	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1042417002002	dimer interface [polypeptide binding]; other site
1042417002003	ADP-ribose binding site [chemical binding]; other site
1042417002004	active site
1042417002005	nudix motif; other site
1042417002006	metal binding site [ion binding]; metal-binding site
1042417002007	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1042417002008	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1042417002009	dimer interface [polypeptide binding]; other site
1042417002010	phosphorylation site [posttranslational modification]
1042417002011	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417002012	ATP binding site [chemical binding]; other site
1042417002013	Mg2+ binding site [ion binding]; other site
1042417002014	G-X-G motif; other site
1042417002015	Putative zinc-finger; Region: zf-HC2; pfam13490
1042417002016	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1042417002017	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1042417002018	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417002019	DNA binding residues [nucleotide binding]
1042417002020	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1042417002021	dimer interface [polypeptide binding]; other site
1042417002022	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
1042417002023	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
1042417002024	Ligand binding site; other site
1042417002025	Putative Catalytic site; other site
1042417002026	DXD motif; other site
1042417002027	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1042417002028	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1042417002029	hinge; other site
1042417002030	active site
1042417002031	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
1042417002032	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1042417002033	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1042417002034	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002035	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002036	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002037	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002038	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002039	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002040	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1042417002041	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1042417002042	dimer interface [polypeptide binding]; other site
1042417002043	motif 1; other site
1042417002044	active site
1042417002045	motif 2; other site
1042417002046	motif 3; other site
1042417002047	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1042417002048	anticodon binding site; other site
1042417002049	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1042417002050	Stage II sporulation protein; Region: SpoIID; pfam08486
1042417002051	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1042417002052	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1042417002053	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1042417002054	active site
1042417002055	catalytic residues [active]
1042417002056	DNA binding site [nucleotide binding]
1042417002057	Int/Topo IB signature motif; other site
1042417002058	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
1042417002059	Predicted chitinase [General function prediction only]; Region: COG3179
1042417002060	catalytic residue [active]
1042417002061	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1042417002062	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417002063	DNA binding residues [nucleotide binding]
1042417002064	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1042417002065	Bacteriophage protein of unknown function (DUF646); Region: DUF646; cl12124
1042417002066	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1042417002067	oligomerization interface [polypeptide binding]; other site
1042417002068	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1042417002069	Phage capsid family; Region: Phage_capsid; pfam05065
1042417002070	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
1042417002071	Phage portal protein; Region: Phage_portal; pfam04860
1042417002072	Phage-related protein [Function unknown]; Region: COG4695
1042417002073	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1042417002074	DNA methylase; Region: N6_N4_Mtase; pfam01555
1042417002075	Phage terminase, small subunit; Region: Terminase_4; pfam05119
1042417002076	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1042417002077	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1042417002078	Domain of unknown function (DUF4393); Region: DUF4393; pfam14337
1042417002079	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417002080	ATP binding site [chemical binding]; other site
1042417002081	Mg2+ binding site [ion binding]; other site
1042417002082	G-X-G motif; other site
1042417002083	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1042417002084	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1042417002085	active site
1042417002086	catalytic residues [active]
1042417002087	DNA binding site [nucleotide binding]
1042417002088	Int/Topo IB signature motif; other site
1042417002089	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1042417002090	active site
1042417002091	hypothetical protein; Validated; Region: PRK08116
1042417002092	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417002093	Walker A motif; other site
1042417002094	ATP binding site [chemical binding]; other site
1042417002095	Walker B motif; other site
1042417002096	arginine finger; other site
1042417002097	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
1042417002098	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1042417002099	NAD(P) binding site [chemical binding]; other site
1042417002100	catalytic residues [active]
1042417002101	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1042417002102	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1042417002103	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
1042417002104	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417002105	active site
1042417002106	motif I; other site
1042417002107	motif II; other site
1042417002108	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417002109	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1042417002110	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1042417002111	active site
1042417002112	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1042417002113	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1042417002114	folate binding site [chemical binding]; other site
1042417002115	NADP+ binding site [chemical binding]; other site
1042417002116	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1042417002117	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1042417002118	dimerization interface [polypeptide binding]; other site
1042417002119	active site
1042417002120	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1042417002121	Domain of unknown function DUF21; Region: DUF21; pfam01595
1042417002122	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1042417002123	Transporter associated domain; Region: CorC_HlyC; smart01091
1042417002124	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1042417002125	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1042417002126	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1042417002127	Recombination protein O N terminal; Region: RecO_N; pfam11967
1042417002128	Recombination protein O C terminal; Region: RecO_C; pfam02565
1042417002129	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1042417002130	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417002131	motif II; other site
1042417002132	potential frameshift: common BLAST hit: gi|300871804|ref|YP_003786677.1| NIF3 domain-containing protein
1042417002133	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1042417002134	RNA polymerase sigma factor WhiG; Reviewed; Region: PRK06288
1042417002135	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1042417002136	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1042417002137	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417002138	DNA binding residues [nucleotide binding]
1042417002139	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1042417002140	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1042417002141	P-loop; other site
1042417002142	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1042417002143	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
1042417002144	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1042417002145	flagellar biosynthetic protein FlhF; Region: FlhF; TIGR03499
1042417002146	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
1042417002147	FHIPEP family; Region: FHIPEP; pfam00771
1042417002148	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1042417002149	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1042417002150	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1042417002151	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1042417002152	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1042417002153	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1042417002154	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417002155	Coenzyme A binding pocket [chemical binding]; other site
1042417002156	Predicted permeases [General function prediction only]; Region: COG0730
1042417002157	hypothetical protein; Provisional; Region: PRK10621
1042417002158	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1042417002159	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1042417002160	L-aspartate oxidase; Provisional; Region: PRK06175
1042417002161	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
1042417002162	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1042417002163	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1042417002164	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1042417002165	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1042417002166	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1042417002167	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1042417002168	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1042417002169	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1042417002170	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
1042417002171	potential frameshift: common BLAST hit: gi|300871783|ref|YP_003786656.1| DNA repair protein RadA
1042417002172	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
1042417002173	CAMP factor (Cfa); Region: CAMP_factor; pfam07373
1042417002174	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
1042417002175	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1042417002176	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1042417002177	active site
1042417002178	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1042417002179	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
1042417002180	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1042417002181	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1042417002182	catalytic residue [active]
1042417002183	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1042417002184	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1042417002185	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1042417002186	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
1042417002187	GTP/Mg2+ binding site [chemical binding]; other site
1042417002188	G4 box; other site
1042417002189	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1042417002190	G1 box; other site
1042417002191	G1 box; other site
1042417002192	GTP/Mg2+ binding site [chemical binding]; other site
1042417002193	Switch I region; other site
1042417002194	Switch I region; other site
1042417002195	G2 box; other site
1042417002196	G2 box; other site
1042417002197	Switch II region; other site
1042417002198	G3 box; other site
1042417002199	G4 box; other site
1042417002200	G5 box; other site
1042417002201	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1042417002202	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1042417002203	active site
1042417002204	dimer interface [polypeptide binding]; other site
1042417002205	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
1042417002206	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1042417002207	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
1042417002208	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1042417002209	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417002210	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1042417002211	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1042417002212	ferrochelatase; Reviewed; Region: hemH; PRK00035
1042417002213	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1042417002214	C-terminal domain interface [polypeptide binding]; other site
1042417002215	active site
1042417002216	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1042417002217	active site
1042417002218	N-terminal domain interface [polypeptide binding]; other site
1042417002219	Predicted transcriptional regulator [Transcription]; Region: COG1959
1042417002220	Transcriptional regulator; Region: Rrf2; pfam02082
1042417002221	potential frameshift: common BLAST hit: gi|300871767|ref|YP_003786640.1| cyclic nucleotide-binding protein
1042417002222	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1042417002223	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1042417002224	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1042417002225	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1042417002226	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1042417002227	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1042417002228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417002229	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1042417002230	Walker A motif; other site
1042417002231	ATP binding site [chemical binding]; other site
1042417002232	Walker B motif; other site
1042417002233	arginine finger; other site
1042417002234	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1042417002235	potential frameshift: common BLAST hit: gi|300871761|ref|YP_003786634.1| oligopeptide/dipeptide ABC transporter ATPase
1042417002236	potential frameshift: common BLAST hit: gi|300871760|ref|YP_003786633.1| oligopeptide/dipeptide ABC transporter ATPase
1042417002237	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1042417002238	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1042417002239	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417002240	putative PBP binding loops; other site
1042417002241	dimer interface [polypeptide binding]; other site
1042417002242	ABC-ATPase subunit interface; other site
1042417002243	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1042417002244	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417002245	dimer interface [polypeptide binding]; other site
1042417002246	conserved gate region; other site
1042417002247	putative PBP binding loops; other site
1042417002248	ABC-ATPase subunit interface; other site
1042417002249	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1042417002250	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1042417002251	active site
1042417002252	PHP Thumb interface [polypeptide binding]; other site
1042417002253	metal binding site [ion binding]; metal-binding site
1042417002254	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1042417002255	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1042417002256	Protein of unknown function, DUF486; Region: DUF486; cl01236
1042417002257	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1042417002258	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1042417002259	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1042417002260	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1042417002261	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1042417002262	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1042417002263	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1042417002264	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1042417002265	active site
1042417002266	HIGH motif; other site
1042417002267	nucleotide binding site [chemical binding]; other site
1042417002268	Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786
1042417002269	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1042417002270	putative active site [active]
1042417002271	potential frameshift: common BLAST hit: gi|300871745|ref|YP_003786618.1| acriflavin resistance protein
1042417002272	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1042417002273	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1042417002274	active site
1042417002275	DNA binding site [nucleotide binding]
1042417002276	Int/Topo IB signature motif; other site
1042417002277	DNA gyrase subunit A; Validated; Region: PRK05560
1042417002278	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1042417002279	CAP-like domain; other site
1042417002280	active site
1042417002281	primary dimer interface [polypeptide binding]; other site
1042417002282	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1042417002283	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1042417002284	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1042417002285	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1042417002286	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1042417002287	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1042417002288	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1042417002289	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1042417002290	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1042417002291	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1042417002292	substrate binding site [chemical binding]; other site
1042417002293	ATP binding site [chemical binding]; other site
1042417002294	TPR repeat; Region: TPR_11; pfam13414
1042417002295	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002296	binding surface
1042417002297	TPR motif; other site
1042417002298	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002299	Bifunctional nuclease; Region: DNase-RNase; pfam02577
1042417002300	UvrB/uvrC motif; Region: UVR; pfam02151
1042417002301	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1042417002302	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1042417002303	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1042417002304	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1042417002305	putative CheA interaction surface; other site
1042417002306	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1042417002307	potential frameshift: common BLAST hit: gi|300871727|ref|YP_003786600.1| phosphoesterase
1042417002308	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1042417002309	RNA/DNA hybrid binding site [nucleotide binding]; other site
1042417002310	active site
1042417002311	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1042417002312	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1042417002313	ligand binding site [chemical binding]; other site
1042417002314	flexible hinge region; other site
1042417002315	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1042417002316	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002317	binding surface
1042417002318	TPR motif; other site
1042417002319	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1042417002320	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
1042417002321	ligand binding site [chemical binding]; other site
1042417002322	flexible hinge region; other site
1042417002323	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
1042417002324	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002325	binding surface
1042417002326	TPR motif; other site
1042417002327	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002328	binding surface
1042417002329	TPR motif; other site
1042417002330	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417002331	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417002332	binding surface
1042417002333	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002334	TPR motif; other site
1042417002335	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1042417002336	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1042417002337	Interdomain contacts; other site
1042417002338	Cytokine receptor motif; other site
1042417002339	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1042417002340	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1042417002341	active site
1042417002342	metal binding site [ion binding]; metal-binding site
1042417002343	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1042417002344	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
1042417002345	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
1042417002346	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417002347	FeS/SAM binding site; other site
1042417002348	putative hydrolase; Validated; Region: PRK09248
1042417002349	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1042417002350	active site
1042417002351	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
1042417002352	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1042417002353	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417002354	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002355	TPR motif; other site
1042417002356	TPR repeat; Region: TPR_11; pfam13414
1042417002357	binding surface
1042417002358	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002359	binding surface
1042417002360	TPR motif; other site
1042417002361	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002362	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002363	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1042417002364	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1042417002365	active site
1042417002366	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
1042417002367	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1042417002368	B12 binding site [chemical binding]; other site
1042417002369	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417002370	FeS/SAM binding site; other site
1042417002371	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1042417002372	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1042417002373	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1042417002374	putative active site [active]
1042417002375	putative metal binding site [ion binding]; other site
1042417002376	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1042417002377	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1042417002378	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1042417002379	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1042417002380	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1042417002381	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1042417002382	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417002383	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
1042417002384	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417002385	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417002386	active site
1042417002387	catalytic tetrad [active]
1042417002388	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1042417002389	Clp amino terminal domain; Region: Clp_N; pfam02861
1042417002390	Clp amino terminal domain; Region: Clp_N; pfam02861
1042417002391	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417002392	Walker A motif; other site
1042417002393	ATP binding site [chemical binding]; other site
1042417002394	Walker B motif; other site
1042417002395	arginine finger; other site
1042417002396	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417002397	Walker A motif; other site
1042417002398	ATP binding site [chemical binding]; other site
1042417002399	Walker B motif; other site
1042417002400	arginine finger; other site
1042417002401	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1042417002402	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1042417002403	ligand binding site [chemical binding]; other site
1042417002404	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1042417002405	substrate binding site [chemical binding]; other site
1042417002406	multimerization interface [polypeptide binding]; other site
1042417002407	ATP binding site [chemical binding]; other site
1042417002408	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1042417002409	Nucleoside recognition; Region: Gate; pfam07670
1042417002410	Rubrerythrin [Energy production and conversion]; Region: COG1592
1042417002411	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1042417002412	binuclear metal center [ion binding]; other site
1042417002413	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
1042417002414	iron binding site [ion binding]; other site
1042417002415	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1042417002416	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1042417002417	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1042417002418	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1042417002419	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1042417002420	tandem repeat interface [polypeptide binding]; other site
1042417002421	oligomer interface [polypeptide binding]; other site
1042417002422	active site residues [active]
1042417002423	Predicted permeases [General function prediction only]; Region: COG0795
1042417002424	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1042417002425	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1042417002426	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1042417002427	NHL repeat; Region: NHL; pfam01436
1042417002428	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1042417002429	NHL repeat; Region: NHL; pfam01436
1042417002430	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1042417002431	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1042417002432	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1042417002433	catalytic residue [active]
1042417002434	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
1042417002435	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1042417002436	Walker A motif/ATP binding site; other site
1042417002437	Walker B motif; other site
1042417002438	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1042417002439	Flagellar assembly protein FliH; Region: FliH; pfam02108
1042417002440	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1042417002441	FliG C-terminal domain; Region: FliG_C; pfam01706
1042417002442	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1042417002443	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1042417002444	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1042417002445	Competence-damaged protein; Region: CinA; pfam02464
1042417002446	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1042417002447	AzlC protein; Region: AzlC; cl00570
1042417002448	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1042417002449	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
1042417002450	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1042417002451	dimer interface [polypeptide binding]; other site
1042417002452	catalytic residues [active]
1042417002453	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1042417002454	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1042417002455	dimer interface [polypeptide binding]; other site
1042417002456	catalytic triad [active]
1042417002457	peroxidatic and resolving cysteines [active]
1042417002458	potential frameshift: common BLAST hit: gi|300871669|ref|YP_003786542.1| UDP-N-acetylmuramyl-tripeptide synthetase
1042417002459	MraW methylase family; Region: Methyltransf_5; cl17771
1042417002460	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1042417002461	excinuclease ABC subunit B; Provisional; Region: PRK05298
1042417002462	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417002463	ATP binding site [chemical binding]; other site
1042417002464	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417002465	nucleotide binding region [chemical binding]; other site
1042417002466	ATP-binding site [chemical binding]; other site
1042417002467	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1042417002468	UvrB/uvrC motif; Region: UVR; pfam02151
1042417002469	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417002470	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1042417002471	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1042417002472	active site
1042417002473	catalytic triad [active]
1042417002474	oxyanion hole [active]
1042417002475	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1042417002476	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1042417002477	putative acyl-acceptor binding pocket; other site
1042417002478	Leucine rich repeat; Region: LRR_8; pfam13855
1042417002479	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417002480	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417002481	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417002482	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417002483	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417002484	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1042417002485	catalytic triad [active]
1042417002486	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1042417002487	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417002488	S-adenosylmethionine binding site [chemical binding]; other site
1042417002489	potential frameshift: common BLAST hit: gi|300871653|ref|YP_003786526.1| alginate O-acetylation protein
1042417002490	DNA primase; Validated; Region: dnaG; PRK05667
1042417002491	CHC2 zinc finger; Region: zf-CHC2; cl17510
1042417002492	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1042417002493	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1042417002494	active site
1042417002495	metal binding site [ion binding]; metal-binding site
1042417002496	interdomain interaction site; other site
1042417002497	potential frameshift: common BLAST hit: gi|296127158|ref|YP_003634410.1| RNA polymerase, sigma 70 subunit, RpoD subfamily
1042417002498	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1042417002499	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1042417002500	acyl-activating enzyme (AAE) consensus motif; other site
1042417002501	putative AMP binding site [chemical binding]; other site
1042417002502	putative active site [active]
1042417002503	putative CoA binding site [chemical binding]; other site
1042417002504	potential frameshift: common BLAST hit: gi|300871649|ref|YP_003786522.1| mannosyltransferase
1042417002505	Predicted permeases [General function prediction only]; Region: COG0701
1042417002506	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1042417002507	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1042417002508	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1042417002509	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417002510	dimer interface [polypeptide binding]; other site
1042417002511	conserved gate region; other site
1042417002512	putative PBP binding loops; other site
1042417002513	ABC-ATPase subunit interface; other site
1042417002514	potential frameshift: common BLAST hit: gi|296127570|ref|YP_003634822.1| ABC transporter ATP-binding protein
1042417002515	Alkylmercury lyase; Region: MerB; pfam03243
1042417002516	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1042417002517	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1042417002518	active site
1042417002519	catalytic site [active]
1042417002520	putative DNA binding site [nucleotide binding]; other site
1042417002521	GIY-YIG motif/motif A; other site
1042417002522	metal binding site [ion binding]; metal-binding site
1042417002523	UvrB/uvrC motif; Region: UVR; pfam02151
1042417002524	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1042417002525	Formaldehyde dehydrogenases; Region: FDH_like; cd05278
1042417002526	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1042417002527	catalytic Zn binding site [ion binding]; other site
1042417002528	NAD(P) binding site [chemical binding]; other site
1042417002529	structural Zn binding site [ion binding]; other site
1042417002530	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1042417002531	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417002532	Mg2+ binding site [ion binding]; other site
1042417002533	G-X-G motif; other site
1042417002534	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1042417002535	anchoring element; other site
1042417002536	dimer interface [polypeptide binding]; other site
1042417002537	ATP binding site [chemical binding]; other site
1042417002538	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1042417002539	active site
1042417002540	putative metal-binding site [ion binding]; other site
1042417002541	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1042417002542	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417002543	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1042417002544	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417002545	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1042417002546	active site
1042417002547	P-loop; other site
1042417002548	phosphorylation site [posttranslational modification]
1042417002549	potential frameshift: common BLAST hit: gi|300871634|ref|YP_003786507.1| 5-nucleotidase-2-3-cyclic phosphodiesterase-like esterase
1042417002550	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1042417002551	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1042417002552	active site
1042417002553	metal binding site [ion binding]; metal-binding site
1042417002554	DNA topoisomerase I; Validated; Region: PRK05582
1042417002555	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1042417002556	active site
1042417002557	interdomain interaction site; other site
1042417002558	putative metal-binding site [ion binding]; other site
1042417002559	nucleotide binding site [chemical binding]; other site
1042417002560	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1042417002561	domain I; other site
1042417002562	DNA binding groove [nucleotide binding]
1042417002563	phosphate binding site [ion binding]; other site
1042417002564	domain II; other site
1042417002565	domain III; other site
1042417002566	nucleotide binding site [chemical binding]; other site
1042417002567	catalytic site [active]
1042417002568	domain IV; other site
1042417002569	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1042417002570	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1042417002571	DNA protecting protein DprA; Region: dprA; TIGR00732
1042417002572	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1042417002573	TPR repeat; Region: TPR_11; pfam13414
1042417002574	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002575	TPR motif; other site
1042417002576	binding surface
1042417002577	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
1042417002578	Asp-box motif; other site
1042417002579	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
1042417002580	active site
1042417002581	substrate-binding site [chemical binding]; other site
1042417002582	metal-binding site [ion binding]
1042417002583	GTP binding site [chemical binding]; other site
1042417002584	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417002585	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417002586	peptide binding site [polypeptide binding]; other site
1042417002587	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
1042417002588	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
1042417002589	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417002590	FeS/SAM binding site; other site
1042417002591	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1042417002592	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
1042417002593	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
1042417002594	G1 box; other site
1042417002595	GTP/Mg2+ binding site [chemical binding]; other site
1042417002596	Switch I region; other site
1042417002597	G2 box; other site
1042417002598	Switch II region; other site
1042417002599	G3 box; other site
1042417002600	G4 box; other site
1042417002601	G5 box; other site
1042417002602	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
1042417002603	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417002604	FeS/SAM binding site; other site
1042417002605	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1042417002606	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1042417002607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417002608	Coenzyme A binding pocket [chemical binding]; other site
1042417002609	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417002610	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417002611	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1042417002612	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1042417002613	conserved cys residue [active]
1042417002614	glycogen synthase; Provisional; Region: glgA; PRK00654
1042417002615	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1042417002616	ADP-binding pocket [chemical binding]; other site
1042417002617	homodimer interface [polypeptide binding]; other site
1042417002618	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
1042417002619	ligand binding site [chemical binding]; other site
1042417002620	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1042417002621	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002622	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002623	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002624	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002625	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002626	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002627	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002628	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002629	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
1042417002630	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1042417002631	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1042417002632	metal binding site [ion binding]; metal-binding site
1042417002633	dimer interface [polypeptide binding]; other site
1042417002634	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002635	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002636	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002637	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002638	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002639	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417002640	Transglycosylase; Region: Transgly; pfam00912
1042417002641	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1042417002642	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1042417002643	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417002644	Competence protein; Region: Competence; pfam03772
1042417002645	FMN-binding domain; Region: FMN_bind; cl01081
1042417002646	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1042417002647	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1042417002648	RNA binding surface [nucleotide binding]; other site
1042417002649	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1042417002650	active site
1042417002651	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1042417002652	trimer interface [polypeptide binding]; other site
1042417002653	active site
1042417002654	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1042417002655	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1042417002656	active site
1042417002657	dimer interface [polypeptide binding]; other site
1042417002658	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1042417002659	dimer interface [polypeptide binding]; other site
1042417002660	active site
1042417002661	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12816
1042417002662	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1042417002663	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1042417002664	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1042417002665	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1042417002666	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1042417002667	catalytic residue [active]
1042417002668	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417002669	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002670	binding surface
1042417002671	TPR motif; other site
1042417002672	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002673	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002674	binding surface
1042417002675	TPR repeat; Region: TPR_11; pfam13414
1042417002676	TPR motif; other site
1042417002677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002678	binding surface
1042417002679	TPR repeat; Region: TPR_11; pfam13414
1042417002680	TPR motif; other site
1042417002681	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417002682	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002683	binding surface
1042417002684	TPR motif; other site
1042417002685	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002686	binding surface
1042417002687	TPR motif; other site
1042417002688	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002689	TPR repeat; Region: TPR_11; pfam13414
1042417002690	TPR motif; other site
1042417002691	binding surface
1042417002692	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1042417002693	Predicted solute binding protein [General function prediction only]; Region: COG3889
1042417002694	CTP synthetase; Validated; Region: pyrG; PRK05380
1042417002695	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1042417002696	Catalytic site [active]
1042417002697	active site
1042417002698	UTP binding site [chemical binding]; other site
1042417002699	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1042417002700	active site
1042417002701	putative oxyanion hole; other site
1042417002702	catalytic triad [active]
1042417002703	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
1042417002704	prephenate dehydrogenase; Validated; Region: PRK08507
1042417002705	LabA_like proteins; Region: LabA_like; cd06167
1042417002706	putative metal binding site [ion binding]; other site
1042417002707	potential frameshift: common BLAST hit: gi|300871589|ref|YP_003786462.1| putative glycosyl transferase family 2 protein
1042417002708	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1042417002709	Rubredoxin [Energy production and conversion]; Region: COG1773
1042417002710	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1042417002711	iron binding site [ion binding]; other site
1042417002712	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1042417002713	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1042417002714	intersubunit interface [polypeptide binding]; other site
1042417002715	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1042417002716	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1042417002717	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1042417002718	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1042417002719	ABC-ATPase subunit  interface; other site
1042417002720	dimer interface [polypeptide binding]; other site
1042417002721	putative PBP binding regions; other site
1042417002722	GTP-binding protein LepA; Provisional; Region: PRK05433
1042417002723	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1042417002724	G1 box; other site
1042417002725	putative GEF interaction site [polypeptide binding]; other site
1042417002726	GTP/Mg2+ binding site [chemical binding]; other site
1042417002727	Switch I region; other site
1042417002728	G2 box; other site
1042417002729	G3 box; other site
1042417002730	Switch II region; other site
1042417002731	G4 box; other site
1042417002732	G5 box; other site
1042417002733	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1042417002734	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1042417002735	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1042417002736	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1042417002737	B3/4 domain; Region: B3_4; pfam03483
1042417002738	potential frameshift: common BLAST hit: gi|300871581|ref|YP_003786454.1| radical SAM domain-containing protein
1042417002739	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1042417002740	S-adenosylmethionine binding site [chemical binding]; other site
1042417002741	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1042417002742	active site
1042417002743	catalytic residues [active]
1042417002744	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1042417002745	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1042417002746	Predicted membrane protein [Function unknown]; Region: COG2364
1042417002747	MarR family; Region: MarR_2; cl17246
1042417002748	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1042417002749	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417002750	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1042417002751	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1042417002752	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1042417002753	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1042417002754	Walker A/P-loop; other site
1042417002755	ATP binding site [chemical binding]; other site
1042417002756	Q-loop/lid; other site
1042417002757	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1042417002758	Q-loop/lid; other site
1042417002759	ABC transporter signature motif; other site
1042417002760	Walker B; other site
1042417002761	D-loop; other site
1042417002762	H-loop/switch region; other site
1042417002763	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
1042417002764	putative FMN binding site [chemical binding]; other site
1042417002765	CobD/Cbib protein; Region: CobD_Cbib; cl00561
1042417002766	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1042417002767	catalytic core [active]
1042417002768	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
1042417002769	nucleophile elbow; other site
1042417002770	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1042417002771	N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases; Region: FpgNei_N; cl03119
1042417002772	DNA binding site [nucleotide binding]
1042417002773	catalytic residue [active]
1042417002774	H2TH interface [polypeptide binding]; other site
1042417002775	putative catalytic residues [active]
1042417002776	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1042417002777	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1042417002778	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1042417002779	dimer interface [polypeptide binding]; other site
1042417002780	ssDNA binding site [nucleotide binding]; other site
1042417002781	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1042417002782	thymidylate kinase; Validated; Region: tmk; PRK00698
1042417002783	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1042417002784	TMP-binding site; other site
1042417002785	ATP-binding site [chemical binding]; other site
1042417002786	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1042417002787	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1042417002788	Mg++ binding site [ion binding]; other site
1042417002789	putative catalytic motif [active]
1042417002790	putative substrate binding site [chemical binding]; other site
1042417002791	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1042417002792	classical (c) SDRs; Region: SDR_c; cd05233
1042417002793	NAD(P) binding site [chemical binding]; other site
1042417002794	active site
1042417002795	DNA polymerase III subunit beta; Validated; Region: PRK05643
1042417002796	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1042417002797	putative DNA binding surface [nucleotide binding]; other site
1042417002798	dimer interface [polypeptide binding]; other site
1042417002799	beta-clamp/clamp loader binding surface; other site
1042417002800	beta-clamp/translesion DNA polymerase binding surface; other site
1042417002801	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1042417002802	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1042417002803	inhibitor-cofactor binding pocket; inhibition site
1042417002804	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417002805	catalytic residue [active]
1042417002806	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1042417002807	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1042417002808	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1042417002809	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1042417002810	GTP-binding protein Der; Reviewed; Region: PRK00093
1042417002811	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1042417002812	G1 box; other site
1042417002813	GTP/Mg2+ binding site [chemical binding]; other site
1042417002814	Switch I region; other site
1042417002815	G2 box; other site
1042417002816	Switch II region; other site
1042417002817	G3 box; other site
1042417002818	G4 box; other site
1042417002819	G5 box; other site
1042417002820	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1042417002821	G1 box; other site
1042417002822	GTP/Mg2+ binding site [chemical binding]; other site
1042417002823	Switch I region; other site
1042417002824	G2 box; other site
1042417002825	G3 box; other site
1042417002826	Switch II region; other site
1042417002827	G4 box; other site
1042417002828	G5 box; other site
1042417002829	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1042417002830	potential frameshift: common BLAST hit: gi|300871550|ref|YP_003786423.1| fatty acid/phospholipid synthesis protein
1042417002831	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1042417002832	active site
1042417002833	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1042417002834	SLBB domain; Region: SLBB; pfam10531
1042417002835	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1042417002836	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
1042417002837	FMN-binding domain; Region: FMN_bind; cl01081
1042417002838	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002839	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002840	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002841	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002842	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002843	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002844	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002845	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002846	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002847	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002848	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002849	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002850	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002851	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002852	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002853	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002854	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002855	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002856	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417002857	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002858	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417002859	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417002860	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1042417002861	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1042417002862	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1042417002863	active site
1042417002864	HIGH motif; other site
1042417002865	dimer interface [polypeptide binding]; other site
1042417002866	KMSKS motif; other site
1042417002867	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1042417002868	active site residue [active]
1042417002869	Ribosomal protein L31; Region: Ribosomal_L31; cl00377
1042417002870	DNA mismatch repair protein MutL; Region: mutl; TIGR00585
1042417002871	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417002872	ATP binding site [chemical binding]; other site
1042417002873	Mg2+ binding site [ion binding]; other site
1042417002874	G-X-G motif; other site
1042417002875	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1042417002876	ATP binding site [chemical binding]; other site
1042417002877	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1042417002878	potential frameshift: common BLAST hit: gi|300871534|ref|YP_003786407.1| DNA segregation ATPase FtsK/SpoIIIE-like protein
1042417002879	Bacitracin resistance protein BacA; Region: BacA; pfam02673
1042417002880	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1042417002881	non-specific DNA binding site [nucleotide binding]; other site
1042417002882	salt bridge; other site
1042417002883	sequence-specific DNA binding site [nucleotide binding]; other site
1042417002884	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417002885	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1042417002886	TPR motif; other site
1042417002887	binding surface
1042417002888	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417002889	binding surface
1042417002890	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417002891	TPR motif; other site
1042417002892	Domain of unknown function (DUF368); Region: DUF368; pfam04018
1042417002893	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1042417002894	homotrimer interaction site [polypeptide binding]; other site
1042417002895	putative active site [active]
1042417002896	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1042417002897	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1042417002898	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417002899	active site
1042417002900	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1042417002901	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
1042417002902	5S rRNA interface [nucleotide binding]; other site
1042417002903	CTC domain interface [polypeptide binding]; other site
1042417002904	L16 interface [polypeptide binding]; other site
1042417002905	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1042417002906	putative active site [active]
1042417002907	catalytic residue [active]
1042417002908	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1042417002909	putative active site [active]
1042417002910	catalytic residue [active]
1042417002911	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1042417002912	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
1042417002913	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417002914	Walker A/P-loop; other site
1042417002915	ATP binding site [chemical binding]; other site
1042417002916	Q-loop/lid; other site
1042417002917	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417002918	ABC transporter signature motif; other site
1042417002919	Walker B; other site
1042417002920	D-loop; other site
1042417002921	H-loop/switch region; other site
1042417002922	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1042417002923	HPr interaction site; other site
1042417002924	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1042417002925	active site
1042417002926	phosphorylation site [posttranslational modification]
1042417002927	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1042417002928	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417002929	active site
1042417002930	phosphorylation site [posttranslational modification]
1042417002931	intermolecular recognition site; other site
1042417002932	dimerization interface [polypeptide binding]; other site
1042417002933	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417002934	Walker A motif; other site
1042417002935	ATP binding site [chemical binding]; other site
1042417002936	Walker B motif; other site
1042417002937	arginine finger; other site
1042417002938	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1042417002939	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1042417002940	dimer interface [polypeptide binding]; other site
1042417002941	phosphorylation site [posttranslational modification]
1042417002942	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417002943	ATP binding site [chemical binding]; other site
1042417002944	G-X-G motif; other site
1042417002945	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1042417002946	active site
1042417002947	catalytic residues [active]
1042417002948	metal binding site [ion binding]; metal-binding site
1042417002949	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1042417002950	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417002951	motif II; other site
1042417002952	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1042417002953	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417002954	Predicted transcriptional regulators [Transcription]; Region: COG1733
1042417002955	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1042417002956	potential frameshift: common BLAST hit: gi|300871514|ref|YP_003786387.1| family 5 extracellular solute-binding protein
1042417002957	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1042417002958	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1042417002959	putative active site [active]
1042417002960	putative metal binding site [ion binding]; other site
1042417002961	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1042417002962	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417002963	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1042417002964	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417002965	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1042417002966	Protein of unknown function DUF58; Region: DUF58; pfam01882
1042417002967	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1042417002968	metal ion-dependent adhesion site (MIDAS); other site
1042417002969	Putative Fe-S cluster; Region: FeS; cl17515
1042417002970	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1042417002971	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Region: NuoI; COG1143
1042417002972	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
1042417002973	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1042417002974	gamma-glutamyl kinase; Provisional; Region: PRK05429
1042417002975	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1042417002976	nucleotide binding site [chemical binding]; other site
1042417002977	homotetrameric interface [polypeptide binding]; other site
1042417002978	putative phosphate binding site [ion binding]; other site
1042417002979	putative allosteric binding site; other site
1042417002980	PUA domain; Region: PUA; pfam01472
1042417002981	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417002982	Alpha-helical domain of archaeal GINS complex proteins; Region: GINS_A_archaea; cd11714
1042417002983	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417002984	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1042417002985	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1042417002986	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1042417002987	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1042417002988	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417002989	Coenzyme A binding pocket [chemical binding]; other site
1042417002990	recombinase A; Provisional; Region: recA; PRK09354
1042417002991	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1042417002992	hexamer interface [polypeptide binding]; other site
1042417002993	Walker A motif; other site
1042417002994	ATP binding site [chemical binding]; other site
1042417002995	Walker B motif; other site
1042417002996	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
1042417002997	potential frameshift: common BLAST hit: gi|300871499|ref|YP_003786372.1| MATE efflux family protein
1042417002998	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417002999	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417003000	dimer interface [polypeptide binding]; other site
1042417003001	putative CheW interface [polypeptide binding]; other site
1042417003002	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1042417003003	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1042417003004	metal-binding site [ion binding]
1042417003005	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1042417003006	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417003007	motif II; other site
1042417003008	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
1042417003009	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1042417003010	putative CheA interaction surface; other site
1042417003011	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1042417003012	PilZ domain; Region: PilZ; pfam07238
1042417003013	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1042417003014	active site
1042417003015	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003016	binding surface
1042417003017	TPR motif; other site
1042417003018	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003019	TPR motif; other site
1042417003020	binding surface
1042417003021	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417003022	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003023	binding surface
1042417003024	TPR motif; other site
1042417003025	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417003026	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417003027	active site
1042417003028	catalytic tetrad [active]
1042417003029	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1042417003030	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1042417003031	DNA-binding site [nucleotide binding]; DNA binding site
1042417003032	UTRA domain; Region: UTRA; pfam07702
1042417003033	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1042417003034	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1042417003035	phosphate binding site [ion binding]; other site
1042417003036	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417003037	dimer interface [polypeptide binding]; other site
1042417003038	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1042417003039	putative CheW interface [polypeptide binding]; other site
1042417003040	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1042417003041	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1042417003042	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1042417003043	PhoU domain; Region: PhoU; pfam01895
1042417003044	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1042417003045	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1042417003046	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417003047	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003048	binding surface
1042417003049	TPR motif; other site
1042417003050	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417003051	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1042417003052	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417003053	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1042417003054	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1042417003055	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1042417003056	Cl- selectivity filter; other site
1042417003057	Cl- binding residues [ion binding]; other site
1042417003058	pore gating glutamate residue; other site
1042417003059	dimer interface [polypeptide binding]; other site
1042417003060	H+/Cl- coupling transport residue; other site
1042417003061	GTP-binding protein YchF; Reviewed; Region: PRK09601
1042417003062	YchF GTPase; Region: YchF; cd01900
1042417003063	G1 box; other site
1042417003064	GTP/Mg2+ binding site [chemical binding]; other site
1042417003065	Switch I region; other site
1042417003066	G2 box; other site
1042417003067	Switch II region; other site
1042417003068	G3 box; other site
1042417003069	G4 box; other site
1042417003070	G5 box; other site
1042417003071	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1042417003072	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1042417003073	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1042417003074	iron-sulfur cluster [ion binding]; other site
1042417003075	[2Fe-2S] cluster binding site [ion binding]; other site
1042417003076	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1042417003077	hydrophobic ligand binding site; other site
1042417003078	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1042417003079	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1042417003080	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1042417003081	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1042417003082	Fatty acid synthesis protein; Region: FA_synthesis; cl17261
1042417003083	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
1042417003084	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1042417003085	dimer interface [polypeptide binding]; other site
1042417003086	active site
1042417003087	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1042417003088	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417003089	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417003090	amino acid transporter; Region: 2A0306; TIGR00909
1042417003091	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1042417003092	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1042417003093	catalytic triad [active]
1042417003094	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1042417003095	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1042417003096	metal binding site [ion binding]; metal-binding site
1042417003097	dimer interface [polypeptide binding]; other site
1042417003098	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417003099	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417003100	peptide binding site [polypeptide binding]; other site
1042417003101	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417003102	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1042417003103	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1042417003104	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417003105	dimer interface [polypeptide binding]; other site
1042417003106	putative CheW interface [polypeptide binding]; other site
1042417003107	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1042417003108	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1042417003109	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1042417003110	active site
1042417003111	HIGH motif; other site
1042417003112	nucleotide binding site [chemical binding]; other site
1042417003113	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1042417003114	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1042417003115	active site
1042417003116	KMSKS motif; other site
1042417003117	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1042417003118	tRNA binding surface [nucleotide binding]; other site
1042417003119	anticodon binding site; other site
1042417003120	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1042417003121	Protein of unknown function (DUF2806); Region: DUF2806; cl12560
1042417003122	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1042417003123	RelB antitoxin; Region: RelB; cl01171
1042417003124	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1042417003125	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417003126	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417003127	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003128	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003129	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003130	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003131	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003132	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417003133	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417003134	active site
1042417003135	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003136	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
1042417003137	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
1042417003138	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417003139	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
1042417003140	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
1042417003141	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417003142	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1042417003143	AAA domain; Region: AAA_21; pfam13304
1042417003144	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1042417003145	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1042417003146	active site
1042417003147	metal binding site [ion binding]; metal-binding site
1042417003148	N-glycosylase/DNA lyase; Provisional; Region: PRK01229
1042417003149	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1042417003150	minor groove reading motif; other site
1042417003151	helix-hairpin-helix signature motif; other site
1042417003152	active site
1042417003153	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1042417003154	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1042417003155	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1042417003156	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1042417003157	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1042417003158	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1042417003159	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1042417003160	dimer interface [polypeptide binding]; other site
1042417003161	motif 1; other site
1042417003162	active site
1042417003163	motif 2; other site
1042417003164	motif 3; other site
1042417003165	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1042417003166	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1042417003167	putative tRNA-binding site [nucleotide binding]; other site
1042417003168	B3/4 domain; Region: B3_4; pfam03483
1042417003169	tRNA synthetase B5 domain; Region: B5; pfam03484
1042417003170	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1042417003171	dimer interface [polypeptide binding]; other site
1042417003172	motif 1; other site
1042417003173	motif 3; other site
1042417003174	motif 2; other site
1042417003175	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1042417003176	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417003177	active site
1042417003178	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1042417003179	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417003180	Outer membrane efflux protein; Region: OEP; pfam02321
1042417003181	Outer membrane efflux protein; Region: OEP; pfam02321
1042417003182	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1042417003183	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1042417003184	homotrimer interaction site [polypeptide binding]; other site
1042417003185	zinc binding site [ion binding]; other site
1042417003186	CDP-binding sites; other site
1042417003187	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
1042417003188	substrate binding pocket [chemical binding]; other site
1042417003189	substrate-Mg2+ binding site; other site
1042417003190	aspartate-rich region 1; other site
1042417003191	aspartate-rich region 2; other site
1042417003192	TspO/MBR family; Region: TspO_MBR; pfam03073
1042417003193	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1042417003194	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1042417003195	potential frameshift: common BLAST hit: gi|300871421|ref|YP_003786294.1| putative haloacid dehalogenase like hydrolase
1042417003196	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417003197	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1042417003198	active site
1042417003199	motif I; other site
1042417003200	motif II; other site
1042417003201	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417003202	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417003203	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1042417003204	TM-ABC transporter signature motif; other site
1042417003205	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417003206	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1042417003207	TM-ABC transporter signature motif; other site
1042417003208	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
1042417003209	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1042417003210	Walker A/P-loop; other site
1042417003211	ATP binding site [chemical binding]; other site
1042417003212	Q-loop/lid; other site
1042417003213	ABC transporter signature motif; other site
1042417003214	Walker B; other site
1042417003215	D-loop; other site
1042417003216	H-loop/switch region; other site
1042417003217	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1042417003218	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1042417003219	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1042417003220	ligand binding site [chemical binding]; other site
1042417003221	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1042417003222	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1042417003223	ligand binding site [chemical binding]; other site
1042417003224	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1042417003225	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1042417003226	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1042417003227	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1042417003228	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1042417003229	intersubunit interface [polypeptide binding]; other site
1042417003230	active site
1042417003231	catalytic residue [active]
1042417003232	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417003233	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417003234	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1042417003235	Clp amino terminal domain; Region: Clp_N; pfam02861
1042417003236	Clp amino terminal domain; Region: Clp_N; pfam02861
1042417003237	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417003238	Walker A motif; other site
1042417003239	ATP binding site [chemical binding]; other site
1042417003240	Walker B motif; other site
1042417003241	arginine finger; other site
1042417003242	UvrB/uvrC motif; Region: UVR; pfam02151
1042417003243	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417003244	Walker A motif; other site
1042417003245	ATP binding site [chemical binding]; other site
1042417003246	Walker B motif; other site
1042417003247	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1042417003248	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1042417003249	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1042417003250	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417003251	DNA binding residues [nucleotide binding]
1042417003252	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417003253	Walker A motif; other site
1042417003254	ATP binding site [chemical binding]; other site
1042417003255	Walker B motif; other site
1042417003256	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1042417003257	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1042417003258	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1042417003259	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417003260	FeS/SAM binding site; other site
1042417003261	Helix-turn-helix domain; Region: HTH_25; pfam13413
1042417003262	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1042417003263	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417003264	TPR repeat; Region: TPR_11; pfam13414
1042417003265	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417003266	binding surface
1042417003267	TPR motif; other site
1042417003268	Uncharacterized N-terminal domain of the transcription elongation factor GreA [Function unknown]; Region: COG1747
1042417003269	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1042417003270	active site
1042417003271	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1042417003272	nucleotide binding site/active site [active]
1042417003273	HIT family signature motif; other site
1042417003274	catalytic residue [active]
1042417003275	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1042417003276	ZIP Zinc transporter; Region: Zip; pfam02535
1042417003277	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1042417003278	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1042417003279	Walker A/P-loop; other site
1042417003280	ATP binding site [chemical binding]; other site
1042417003281	Q-loop/lid; other site
1042417003282	ABC transporter signature motif; other site
1042417003283	Walker B; other site
1042417003284	D-loop; other site
1042417003285	H-loop/switch region; other site
1042417003286	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1042417003287	Ferritin-like domain; Region: Ferritin; pfam00210
1042417003288	ferroxidase diiron center [ion binding]; other site
1042417003289	potential frameshift: common BLAST hit: gi|300871392|ref|YP_003786265.1| LexA repressor
1042417003290	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1042417003291	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1042417003292	ligand binding site [chemical binding]; other site
1042417003293	calcium binding site [ion binding]; other site
1042417003294	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1042417003295	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1042417003296	ligand binding site [chemical binding]; other site
1042417003297	calcium binding site [ion binding]; other site
1042417003298	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1042417003299	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1042417003300	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1042417003301	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1042417003302	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1042417003303	Tetramer interface [polypeptide binding]; other site
1042417003304	active site
1042417003305	FMN-binding site [chemical binding]; other site
1042417003306	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1042417003307	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1042417003308	active site
1042417003309	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1042417003310	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417003311	S-adenosylmethionine binding site [chemical binding]; other site
1042417003312	HAMP domain; Region: HAMP; pfam00672
1042417003313	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417003314	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417003315	dimer interface [polypeptide binding]; other site
1042417003316	putative CheW interface [polypeptide binding]; other site
1042417003317	Restriction endonuclease; Region: Mrr_cat; pfam04471
1042417003318	Restriction endonuclease; Region: Mrr_cat; pfam04471
1042417003319	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1042417003320	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1042417003321	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1042417003322	active site
1042417003323	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1042417003324	Protein of unknown function DUF262; Region: DUF262; pfam03235
1042417003325	NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the...; Region: NTR_like; cl02512
1042417003326	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1042417003327	Protein of unknown function DUF262; Region: DUF262; pfam03235
1042417003328	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1042417003329	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1042417003330	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1042417003331	GatB domain; Region: GatB_Yqey; smart00845
1042417003332	thiamine monophosphate kinase; Provisional; Region: PRK05731
1042417003333	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1042417003334	ATP binding site [chemical binding]; other site
1042417003335	dimerization interface [polypeptide binding]; other site
1042417003336	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1042417003337	active site
1042417003338	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1042417003339	peptidase T; Region: peptidase-T; TIGR01882
1042417003340	metal binding site [ion binding]; metal-binding site
1042417003341	dimer interface [polypeptide binding]; other site
1042417003342	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1042417003343	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1042417003344	Ligand Binding Site [chemical binding]; other site
1042417003345	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1042417003346	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1042417003347	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1042417003348	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1042417003349	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1042417003350	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003351	TPR motif; other site
1042417003352	binding surface
1042417003353	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417003354	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003355	binding surface
1042417003356	TPR motif; other site
1042417003357	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417003358	binding surface
1042417003359	TPR repeat; Region: TPR_11; pfam13414
1042417003360	TPR motif; other site
1042417003361	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
1042417003362	YcxB-like protein; Region: YcxB; pfam14317
1042417003363	Ferritin-CCC1, N-terminal ferritin-like diiron-binding domain; Region: Ferritin_CCC1_N; cd01044
1042417003364	diiron binding motif [ion binding]; other site
1042417003365	CCC1-related domain of ferritin; Region: Ferritin_CCC1_C; cd02431
1042417003366	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1042417003367	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1042417003368	metal binding site [ion binding]; metal-binding site
1042417003369	dimer interface [polypeptide binding]; other site
1042417003370	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1042417003371	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417003372	active site
1042417003373	phosphorylation site [posttranslational modification]
1042417003374	intermolecular recognition site; other site
1042417003375	dimerization interface [polypeptide binding]; other site
1042417003376	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1042417003377	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1042417003378	potential frameshift: common BLAST hit: gi|300871357|ref|YP_003786230.1| rod shape-determining protein RodA
1042417003379	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1042417003380	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1042417003381	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1042417003382	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1042417003383	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1042417003384	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1042417003385	protein binding site [polypeptide binding]; other site
1042417003386	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1042417003387	Catalytic dyad [active]
1042417003388	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1042417003389	active site
1042417003390	metal binding site [ion binding]; metal-binding site
1042417003391	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1042417003392	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1042417003393	nucleotide binding site [chemical binding]; other site
1042417003394	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1042417003395	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417003396	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1042417003397	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417003398	active site
1042417003399	Chromate transporter; Region: Chromate_transp; pfam02417
1042417003400	Chromate transporter; Region: Chromate_transp; pfam02417
1042417003401	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417003402	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417003403	peptide binding site [polypeptide binding]; other site
1042417003404	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1042417003405	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1042417003406	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1042417003407	putative NAD(P) binding site [chemical binding]; other site
1042417003408	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1042417003409	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
1042417003410	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
1042417003411	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1042417003412	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1042417003413	homodimer interface [polypeptide binding]; other site
1042417003414	substrate-cofactor binding pocket; other site
1042417003415	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417003416	catalytic residue [active]
1042417003417	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
1042417003418	methionine sulfoxide reductase B; Provisional; Region: PRK05508
1042417003419	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
1042417003420	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1042417003421	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417003422	TM-ABC transporter signature motif; other site
1042417003423	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1042417003424	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1042417003425	Walker A/P-loop; other site
1042417003426	ATP binding site [chemical binding]; other site
1042417003427	Q-loop/lid; other site
1042417003428	ABC transporter signature motif; other site
1042417003429	Walker B; other site
1042417003430	D-loop; other site
1042417003431	H-loop/switch region; other site
1042417003432	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1042417003433	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1042417003434	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1042417003435	ligand binding site [chemical binding]; other site
1042417003436	calcium binding site [ion binding]; other site
1042417003437	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1042417003438	S4 RNA-binding domain; Region: S4; smart00363
1042417003439	RNA binding surface [nucleotide binding]; other site
1042417003440	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1042417003441	active site
1042417003442	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
1042417003443	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1042417003444	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1042417003445	active site
1042417003446	(T/H)XGH motif; other site
1042417003447	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1042417003448	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1042417003449	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417003450	FeS/SAM binding site; other site
1042417003451	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1042417003452	UvrB/uvrC motif; Region: UVR; pfam02151
1042417003453	Phosphagen (guanidino) kinases; Region: phosphagen_kinases; cl02823
1042417003454	ADP binding site [chemical binding]; other site
1042417003455	phosphagen binding site; other site
1042417003456	substrate specificity loop; other site
1042417003457	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiB; COG0543
1042417003458	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
1042417003459	FAD binding pocket [chemical binding]; other site
1042417003460	FAD binding motif [chemical binding]; other site
1042417003461	phosphate binding motif [ion binding]; other site
1042417003462	beta-alpha-beta structure motif; other site
1042417003463	NAD binding pocket [chemical binding]; other site
1042417003464	Iron coordination center [ion binding]; other site
1042417003465	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1042417003466	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417003467	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1042417003468	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
1042417003469	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1042417003470	active site
1042417003471	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1042417003472	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1042417003473	Substrate binding site; other site
1042417003474	Flavoprotein; Region: Flavoprotein; pfam02441
1042417003475	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1042417003476	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1042417003477	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417003478	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1042417003479	Walker A/P-loop; other site
1042417003480	ATP binding site [chemical binding]; other site
1042417003481	Q-loop/lid; other site
1042417003482	ABC transporter signature motif; other site
1042417003483	Walker B; other site
1042417003484	D-loop; other site
1042417003485	H-loop/switch region; other site
1042417003486	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1042417003487	FtsX-like permease family; Region: FtsX; pfam02687
1042417003488	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1042417003489	FtsX-like permease family; Region: FtsX; pfam02687
1042417003490	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1042417003491	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1042417003492	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1042417003493	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1042417003494	phosphopentomutase; Provisional; Region: PRK05362
1042417003495	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1042417003496	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417003497	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1042417003498	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1042417003499	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417003500	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1042417003501	motif II; other site
1042417003502	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1042417003503	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1042417003504	putative dimer interface [polypeptide binding]; other site
1042417003505	[2Fe-2S] cluster binding site [ion binding]; other site
1042417003506	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
1042417003507	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
1042417003508	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1042417003509	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1042417003510	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417003511	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417003512	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1042417003513	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1042417003514	Potassium binding sites [ion binding]; other site
1042417003515	Cesium cation binding sites [ion binding]; other site
1042417003516	DHH family; Region: DHH; pfam01368
1042417003517	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1042417003518	DHHA1 domain; Region: DHHA1; pfam02272
1042417003519	potential frameshift: common BLAST hit: gi|300871301|ref|YP_003786174.1| MATE efflux family protein
1042417003520	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1042417003521	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1042417003522	RF-1 domain; Region: RF-1; pfam00472
1042417003523	spiro-SPASM protein; Region: spiroSPASM; TIGR04321
1042417003524	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1042417003525	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
1042417003526	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
1042417003527	active site
1042417003528	Substrate binding site; other site
1042417003529	Mg++ binding site; other site
1042417003530	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1042417003531	putative trimer interface [polypeptide binding]; other site
1042417003532	putative CoA binding site [chemical binding]; other site
1042417003533	DJ-1 family protein; Region: not_thiJ; TIGR01383
1042417003534	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1042417003535	conserved cys residue [active]
1042417003536	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1042417003537	HIRAN domain; Region: HIRAN; cl07418
1042417003538	Uncharacterized ACR, YggU family COG1872; Region: DUF167; pfam02594
1042417003539	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
1042417003540	Hemerythrin; Region: Hemerythrin; cd12107
1042417003541	Fe binding site [ion binding]; other site
1042417003542	Hemerythrin; Region: Hemerythrin; cd12107
1042417003543	Fe binding site [ion binding]; other site
1042417003544	enolase; Provisional; Region: eno; PRK00077
1042417003545	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1042417003546	dimer interface [polypeptide binding]; other site
1042417003547	metal binding site [ion binding]; metal-binding site
1042417003548	substrate binding pocket [chemical binding]; other site
1042417003549	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
1042417003550	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1042417003551	Ligand binding site; other site
1042417003552	Putative Catalytic site; other site
1042417003553	DXD motif; other site
1042417003554	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1042417003555	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1042417003556	putative catalytic cysteine [active]
1042417003557	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1042417003558	putative active site [active]
1042417003559	metal binding site [ion binding]; metal-binding site
1042417003560	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1042417003561	dimer interface [polypeptide binding]; other site
1042417003562	motif 1; other site
1042417003563	active site
1042417003564	motif 2; other site
1042417003565	motif 3; other site
1042417003566	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1042417003567	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1042417003568	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
1042417003569	NAD binding site [chemical binding]; other site
1042417003570	Phe binding site; other site
1042417003571	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
1042417003572	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1042417003573	active site
1042417003574	putative substrate binding pocket [chemical binding]; other site
1042417003575	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1042417003576	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1042417003577	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1042417003578	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1042417003579	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417003580	dimer interface [polypeptide binding]; other site
1042417003581	conserved gate region; other site
1042417003582	putative PBP binding loops; other site
1042417003583	ABC-ATPase subunit interface; other site
1042417003584	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417003585	dimer interface [polypeptide binding]; other site
1042417003586	conserved gate region; other site
1042417003587	putative PBP binding loops; other site
1042417003588	ABC-ATPase subunit interface; other site
1042417003589	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1042417003590	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417003591	Walker A/P-loop; other site
1042417003592	ATP binding site [chemical binding]; other site
1042417003593	Q-loop/lid; other site
1042417003594	ABC transporter signature motif; other site
1042417003595	Walker B; other site
1042417003596	D-loop; other site
1042417003597	H-loop/switch region; other site
1042417003598	TOBE domain; Region: TOBE_2; pfam08402
1042417003599	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417003600	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1042417003601	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1042417003602	Catalytic site [active]
1042417003603	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1042417003604	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1042417003605	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1042417003606	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
1042417003607	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1042417003608	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1042417003609	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1042417003610	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417003611	potential frameshift: common BLAST hit: gi|300871262|ref|YP_003786135.1| putative transcription elongation factor NusA
1042417003612	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1042417003613	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417003614	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417003615	Divergent AAA domain; Region: AAA_4; pfam04326
1042417003616	Protein of unknown function (DUF4026); Region: DUF4026; pfam13218
1042417003617	SLBB domain; Region: SLBB; pfam10531
1042417003618	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1042417003619	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1042417003620	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417003621	active site
1042417003622	Flagellar basal body-associated protein [Cell motility and secretion]; Region: FliL; COG1580
1042417003623	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
1042417003624	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1042417003625	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1042417003626	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1042417003627	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1042417003628	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1042417003629	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1042417003630	putative substrate binding site [chemical binding]; other site
1042417003631	putative ATP binding site [chemical binding]; other site
1042417003632	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1042417003633	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1042417003634	catalytic residues [active]
1042417003635	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1042417003636	active site
1042417003637	substrate binding site [chemical binding]; other site
1042417003638	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
1042417003639	FMN binding site [chemical binding]; other site
1042417003640	putative catalytic residues [active]
1042417003641	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1042417003642	methionine cluster; other site
1042417003643	active site
1042417003644	phosphorylation site [posttranslational modification]
1042417003645	metal binding site [ion binding]; metal-binding site
1042417003646	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1042417003647	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1042417003648	NAD binding site [chemical binding]; other site
1042417003649	sugar binding site [chemical binding]; other site
1042417003650	divalent metal binding site [ion binding]; other site
1042417003651	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1042417003652	dimer interface [polypeptide binding]; other site
1042417003653	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1042417003654	beta-galactosidase; Region: BGL; TIGR03356
1042417003655	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1042417003656	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1042417003657	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1042417003658	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1042417003659	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1042417003660	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1042417003661	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1042417003662	active site
1042417003663	P-loop; other site
1042417003664	phosphorylation site [posttranslational modification]
1042417003665	HTH domain; Region: HTH_11; pfam08279
1042417003666	Mga helix-turn-helix domain; Region: Mga; pfam05043
1042417003667	PRD domain; Region: PRD; pfam00874
1042417003668	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1042417003669	active site
1042417003670	P-loop; other site
1042417003671	phosphorylation site [posttranslational modification]
1042417003672	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
1042417003673	active site
1042417003674	phosphorylation site [posttranslational modification]
1042417003675	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1042417003676	dimerization domain swap beta strand [polypeptide binding]; other site
1042417003677	regulatory protein interface [polypeptide binding]; other site
1042417003678	active site
1042417003679	regulatory phosphorylation site [posttranslational modification]; other site
1042417003680	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1042417003681	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1042417003682	RNase E interface [polypeptide binding]; other site
1042417003683	trimer interface [polypeptide binding]; other site
1042417003684	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1042417003685	RNase E interface [polypeptide binding]; other site
1042417003686	trimer interface [polypeptide binding]; other site
1042417003687	active site
1042417003688	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1042417003689	putative nucleic acid binding region [nucleotide binding]; other site
1042417003690	G-X-X-G motif; other site
1042417003691	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1042417003692	RNA binding site [nucleotide binding]; other site
1042417003693	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1042417003694	16S/18S rRNA binding site [nucleotide binding]; other site
1042417003695	S13e-L30e interaction site [polypeptide binding]; other site
1042417003696	25S rRNA binding site [nucleotide binding]; other site
1042417003697	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1042417003698	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1042417003699	active site
1042417003700	Riboflavin kinase; Region: Flavokinase; smart00904
1042417003701	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1042417003702	anti sigma factor interaction site; other site
1042417003703	regulatory phosphorylation site [posttranslational modification]; other site
1042417003704	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1042417003705	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417003706	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417003707	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1042417003708	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417003709	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417003710	peptide binding site [polypeptide binding]; other site
1042417003711	heat shock protein 90; Provisional; Region: PRK05218
1042417003712	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417003713	ATP binding site [chemical binding]; other site
1042417003714	Mg2+ binding site [ion binding]; other site
1042417003715	G-X-G motif; other site
1042417003716	potential frameshift: common BLAST hit: gi|300871228|ref|YP_003786101.1| nuclease-like protein
1042417003717	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
1042417003718	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1042417003719	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417003720	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1042417003721	active site
1042417003722	dimer interface [polypeptide binding]; other site
1042417003723	metal binding site [ion binding]; metal-binding site
1042417003724	OPT oligopeptide transporter protein; Region: OPT; cl14607
1042417003725	putative oligopeptide transporter, OPT family; Region: TIGR00733
1042417003726	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1042417003727	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1042417003728	metal binding site [ion binding]; metal-binding site
1042417003729	dimer interface [polypeptide binding]; other site
1042417003730	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1042417003731	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1042417003732	intersubunit interface [polypeptide binding]; other site
1042417003733	active site
1042417003734	zinc binding site [ion binding]; other site
1042417003735	Na+ binding site [ion binding]; other site
1042417003736	Uncharacterized conserved protein [Function unknown]; Region: COG1912
1042417003737	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1042417003738	Fe-S cluster binding site [ion binding]; other site
1042417003739	active site
1042417003740	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417003741	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417003742	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417003743	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1042417003744	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1042417003745	Na2 binding site [ion binding]; other site
1042417003746	putative substrate binding site 1 [chemical binding]; other site
1042417003747	Na binding site 1 [ion binding]; other site
1042417003748	putative substrate binding site 2 [chemical binding]; other site
1042417003749	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1042417003750	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1042417003751	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1042417003752	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1042417003753	30S subunit binding site; other site
1042417003754	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1042417003755	active site
1042417003756	phosphorylation site [posttranslational modification]
1042417003757	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1042417003758	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
1042417003759	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1042417003760	Hpr binding site; other site
1042417003761	active site
1042417003762	homohexamer subunit interaction site [polypeptide binding]; other site
1042417003763	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1042417003764	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1042417003765	Ligand Binding Site [chemical binding]; other site
1042417003766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832
1042417003767	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1042417003768	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1042417003769	Ribosomal prokaryotic L21 protein; Region: Ribosomal_L21p; cl00382
1042417003770	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1042417003771	SurA N-terminal domain; Region: SurA_N; pfam09312
1042417003772	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
1042417003773	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1042417003774	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1042417003775	thymidine kinase; Provisional; Region: PTZ00293
1042417003776	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417003777	binding surface
1042417003778	TPR motif; other site
1042417003779	Restriction endonuclease; Region: Mrr_cat; pfam04471
1042417003780	Domain of unknown function (DUF305); Region: DUF305; pfam03713
1042417003781	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1042417003782	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1042417003783	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1042417003784	trimer interface [polypeptide binding]; other site
1042417003785	active site
1042417003786	UDP-GlcNAc binding site [chemical binding]; other site
1042417003787	lipid binding site [chemical binding]; lipid-binding site
1042417003788	potential frameshift: common BLAST hit: gi|300871197|ref|YP_003786070.1| putative integral membrane protein
1042417003789	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1042417003790	Protein export membrane protein; Region: SecD_SecF; cl14618
1042417003791	potential frameshift: common BLAST hit: gi|300871195|ref|YP_003786068.1| putative Fe-S oxidoreductase
1042417003792	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1042417003793	SmpB-tmRNA interface; other site
1042417003794	potential frameshift: common BLAST hit: gi|300871193|ref|YP_003786066.1| regulatory protein LacI
1042417003795	D-ribose pyranase; Provisional; Region: PRK11797
1042417003796	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1042417003797	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1042417003798	Walker A/P-loop; other site
1042417003799	ATP binding site [chemical binding]; other site
1042417003800	Q-loop/lid; other site
1042417003801	ABC transporter signature motif; other site
1042417003802	Walker B; other site
1042417003803	D-loop; other site
1042417003804	H-loop/switch region; other site
1042417003805	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1042417003806	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1042417003807	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1042417003808	TM-ABC transporter signature motif; other site
1042417003809	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1042417003810	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1042417003811	ligand binding site [chemical binding]; other site
1042417003812	dimerization interface [polypeptide binding]; other site
1042417003813	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1042417003814	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1042417003815	substrate binding site [chemical binding]; other site
1042417003816	dimer interface [polypeptide binding]; other site
1042417003817	ATP binding site [chemical binding]; other site
1042417003818	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1042417003819	dimer interface [polypeptide binding]; other site
1042417003820	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1042417003821	metal ion-dependent adhesion site (MIDAS); other site
1042417003822	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1042417003823	potential frameshift: common BLAST hit: gi|296126688|ref|YP_003633940.1| metal dependent phosphohydrolase
1042417003824	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
1042417003825	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1042417003826	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1042417003827	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
1042417003828	tetramer interface [polypeptide binding]; other site
1042417003829	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417003830	catalytic residue [active]
1042417003831	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1042417003832	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1042417003833	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1042417003834	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1042417003835	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1042417003836	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1042417003837	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1042417003838	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1042417003839	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1042417003840	cleft; other site
1042417003841	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1042417003842	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
1042417003843	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1042417003844	DNA binding site [nucleotide binding]
1042417003845	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1042417003846	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1042417003847	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1042417003848	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1042417003849	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1042417003850	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1042417003851	RPB10 interaction site [polypeptide binding]; other site
1042417003852	RPB1 interaction site [polypeptide binding]; other site
1042417003853	RPB11 interaction site [polypeptide binding]; other site
1042417003854	RPB3 interaction site [polypeptide binding]; other site
1042417003855	RPB12 interaction site [polypeptide binding]; other site
1042417003856	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1042417003857	core dimer interface [polypeptide binding]; other site
1042417003858	peripheral dimer interface [polypeptide binding]; other site
1042417003859	L10 interface [polypeptide binding]; other site
1042417003860	L11 interface [polypeptide binding]; other site
1042417003861	putative EF-Tu interaction site [polypeptide binding]; other site
1042417003862	putative EF-G interaction site [polypeptide binding]; other site
1042417003863	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1042417003864	23S rRNA interface [nucleotide binding]; other site
1042417003865	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1042417003866	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1042417003867	mRNA/rRNA interface [nucleotide binding]; other site
1042417003868	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1042417003869	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1042417003870	23S rRNA interface [nucleotide binding]; other site
1042417003871	L7/L12 interface [polypeptide binding]; other site
1042417003872	putative thiostrepton binding site; other site
1042417003873	L25 interface [polypeptide binding]; other site
1042417003874	potential frameshift: common BLAST hit: gi|300871171|ref|YP_003786043.1| transcription antitermination protein NusG
1042417003875	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1042417003876	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1042417003877	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1042417003878	dimer interface [polypeptide binding]; other site
1042417003879	substrate binding site [chemical binding]; other site
1042417003880	ATP binding site [chemical binding]; other site
1042417003881	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1042417003882	active site
1042417003883	intermolecular recognition site; other site
1042417003884	dimerization interface [polypeptide binding]; other site
1042417003885	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
1042417003886	putative active site pocket [active]
1042417003887	cleavage site
1042417003888	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1042417003889	Uncharacterized conserved protein [Function unknown]; Region: COG1633
1042417003890	Uncharacterized conserved protein [Function unknown]; Region: COG3461
1042417003891	Encapsulating protein for peroxidase; Region: Linocin_M18; pfam04454
1042417003892	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1042417003893	putative active site [active]
1042417003894	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1042417003895	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1042417003896	dimer interface [polypeptide binding]; other site
1042417003897	active site
1042417003898	CoA binding pocket [chemical binding]; other site
1042417003899	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1042417003900	active site
1042417003901	potential frameshift: common BLAST hit: gi|296125875|ref|YP_003633127.1| DNA methylase N-4/N-6 domain protein
1042417003902	putative acyltransferase; Provisional; Region: PRK05790
1042417003903	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1042417003904	dimer interface [polypeptide binding]; other site
1042417003905	active site
1042417003906	potential frameshift: common BLAST hit: gi|300871153|ref|YP_003786025.1| FAD-binding domain-containing protein
1042417003907	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1042417003908	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1042417003909	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1042417003910	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1042417003911	NADP-binding site; other site
1042417003912	homotetramer interface [polypeptide binding]; other site
1042417003913	substrate binding site [chemical binding]; other site
1042417003914	homodimer interface [polypeptide binding]; other site
1042417003915	active site
1042417003916	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1042417003917	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1042417003918	NADP binding site [chemical binding]; other site
1042417003919	active site
1042417003920	putative substrate binding site [chemical binding]; other site
1042417003921	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1042417003922	Ligand binding site; other site
1042417003923	Putative Catalytic site; other site
1042417003924	DXD motif; other site
1042417003925	Preprotein translocase subunit; Region: YajC; pfam02699
1042417003926	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1042417003927	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1042417003928	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1042417003929	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1042417003930	Protein export membrane protein; Region: SecD_SecF; cl14618
1042417003931	potential frameshift: common BLAST hit: gi|300871143|ref|YP_003786015.1| TPR domain-containing protein
1042417003932	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1042417003933	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1042417003934	active site
1042417003935	trimer interface [polypeptide binding]; other site
1042417003936	allosteric site; other site
1042417003937	active site lid [active]
1042417003938	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1042417003939	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1042417003940	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1042417003941	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1042417003942	dimer interface [polypeptide binding]; other site
1042417003943	active site
1042417003944	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1042417003945	folate binding site [chemical binding]; other site
1042417003946	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1042417003947	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1042417003948	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
1042417003949	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1042417003950	TPP-binding site [chemical binding]; other site
1042417003951	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
1042417003952	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1042417003953	dimer interface [polypeptide binding]; other site
1042417003954	PYR/PP interface [polypeptide binding]; other site
1042417003955	TPP binding site [chemical binding]; other site
1042417003956	substrate binding site [chemical binding]; other site
1042417003957	Ferredoxin [Energy production and conversion]; Region: COG1146
1042417003958	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1042417003959	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1042417003960	Walker A/P-loop; other site
1042417003961	ATP binding site [chemical binding]; other site
1042417003962	Q-loop/lid; other site
1042417003963	ABC transporter signature motif; other site
1042417003964	Walker B; other site
1042417003965	D-loop; other site
1042417003966	H-loop/switch region; other site
1042417003967	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1042417003968	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417003969	dimer interface [polypeptide binding]; other site
1042417003970	conserved gate region; other site
1042417003971	putative PBP binding loops; other site
1042417003972	ABC-ATPase subunit interface; other site
1042417003973	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
1042417003974	TPR repeat; Region: TPR_11; pfam13414
1042417003975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417003976	binding surface
1042417003977	TPR motif; other site
1042417003978	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1042417003979	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1042417003980	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1042417003981	putative NAD(P) binding site [chemical binding]; other site
1042417003982	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
1042417003983	potential frameshift: common BLAST hit: gi|300871121|ref|YP_003785993.1| 4-aminobutyrate aminotransferase and-like aminotransferase
1042417003984	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1042417003985	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417003986	Walker A motif; other site
1042417003987	ATP binding site [chemical binding]; other site
1042417003988	Walker B motif; other site
1042417003989	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1042417003990	potential frameshift: common BLAST hit: gi|296126618|ref|YP_003633870.1| NAD-dependent epimerase/dehydratase
1042417003991	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1042417003992	ligand binding site [chemical binding]; other site
1042417003993	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1042417003994	active site
1042417003995	phosphorylation site [posttranslational modification]
1042417003996	intermolecular recognition site; other site
1042417003997	dimerization interface [polypeptide binding]; other site
1042417003998	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1042417003999	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1042417004000	metal binding site [ion binding]; metal-binding site
1042417004001	active site
1042417004002	I-site; other site
1042417004003	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1042417004004	RIP metalloprotease RseP; Region: TIGR00054
1042417004005	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1042417004006	active site
1042417004007	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1042417004008	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1042417004009	protein binding site [polypeptide binding]; other site
1042417004010	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1042417004011	putative substrate binding region [chemical binding]; other site
1042417004012	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
1042417004013	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1042417004014	putative metal binding site [ion binding]; other site
1042417004015	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
1042417004016	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1042417004017	metal ion-dependent adhesion site (MIDAS); other site
1042417004018	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1042417004019	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
1042417004020	putative active site; other site
1042417004021	putative triphosphate binding site [ion binding]; other site
1042417004022	putative metal binding residues [ion binding]; other site
1042417004023	Protein of unknown function (DUF819); Region: DUF819; cl02317
1042417004024	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1042417004025	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1042417004026	dimer interface [polypeptide binding]; other site
1042417004027	anticodon binding site; other site
1042417004028	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1042417004029	homodimer interface [polypeptide binding]; other site
1042417004030	motif 1; other site
1042417004031	active site
1042417004032	motif 2; other site
1042417004033	GAD domain; Region: GAD; pfam02938
1042417004034	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1042417004035	active site
1042417004036	motif 3; other site
1042417004037	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004038	binding surface
1042417004039	TPR motif; other site
1042417004040	TPR repeat; Region: TPR_11; pfam13414
1042417004041	TPR repeat; Region: TPR_11; pfam13414
1042417004042	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004043	binding surface
1042417004044	TPR motif; other site
1042417004045	TPR repeat; Region: TPR_11; pfam13414
1042417004046	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1042417004047	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1042417004048	Phage terminase large subunit; Region: Terminase_3; cl12054
1042417004049	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004050	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417004051	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004052	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004053	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004054	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004055	Protein of unknown function (DUF511); Region: DUF511; cl01114
1042417004056	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
1042417004057	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004058	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004059	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417004060	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004061	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004062	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417004063	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004064	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004065	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1042417004066	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1042417004067	Peptidase family U32; Region: Peptidase_U32; pfam01136
1042417004068	metal binding site [ion binding]; metal-binding site
1042417004069	Collagenase; Region: DUF3656; pfam12392
1042417004070	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1042417004071	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1042417004072	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1042417004073	beta-galactosidase; Region: BGL; TIGR03356
1042417004074	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1042417004075	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417004076	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1042417004077	homopentamer interface [polypeptide binding]; other site
1042417004078	active site
1042417004079	potential frameshift: common BLAST hit: gi|300871037|ref|YP_003785909.1| bifunctional riboflavin biosynthesis protein
1042417004080	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1042417004081	Lumazine binding domain; Region: Lum_binding; pfam00677
1042417004082	Lumazine binding domain; Region: Lum_binding; pfam00677
1042417004083	potential frameshift: common BLAST hit: gi|300871035|ref|YP_003785907.1| riboflavin biosynthesis protein RibD
1042417004084	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
1042417004085	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1042417004086	nudix motif; other site
1042417004087	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1042417004088	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1042417004089	Flagellin N-methylase; Region: FliB; pfam03692
1042417004090	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1042417004091	MarR family; Region: MarR_2; pfam12802
1042417004092	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1042417004093	Na2 binding site [ion binding]; other site
1042417004094	putative substrate binding site 1 [chemical binding]; other site
1042417004095	Na binding site 1 [ion binding]; other site
1042417004096	putative substrate binding site 2 [chemical binding]; other site
1042417004097	potential frameshift: common BLAST hit: gi|300871027|ref|YP_003785899.1| putative 4-diphosphocytidyl-2-C-methyl-d-erythritol kinase
1042417004098	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1042417004099	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1042417004100	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1042417004101	active site
1042417004102	catalytic triad [active]
1042417004103	dimer interface [polypeptide binding]; other site
1042417004104	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1042417004105	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1042417004106	inhibitor-cofactor binding pocket; inhibition site
1042417004107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417004108	catalytic residue [active]
1042417004109	YtxH-like protein; Region: YtxH; pfam12732
1042417004110	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
1042417004111	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1042417004112	Peptidase family M50; Region: Peptidase_M50; pfam02163
1042417004113	active site
1042417004114	putative substrate binding region [chemical binding]; other site
1042417004115	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1042417004116	recombination factor protein RarA; Reviewed; Region: PRK13342
1042417004117	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417004118	Walker A motif; other site
1042417004119	ATP binding site [chemical binding]; other site
1042417004120	Walker B motif; other site
1042417004121	arginine finger; other site
1042417004122	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1042417004123	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1042417004124	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1042417004125	Domain of unknown function (DUF4390); Region: DUF4390; pfam14334
1042417004126	NlpC/P60 family; Region: NLPC_P60; cl17555
1042417004127	FtsH Extracellular; Region: FtsH_ext; pfam06480
1042417004128	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1042417004129	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417004130	Walker A motif; other site
1042417004131	ATP binding site [chemical binding]; other site
1042417004132	Walker B motif; other site
1042417004133	arginine finger; other site
1042417004134	Peptidase family M41; Region: Peptidase_M41; pfam01434
1042417004135	potential frameshift: common BLAST hit: gi|300871006|ref|YP_003785878.1| Na:H+dicarboxylate symporter
1042417004136	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1042417004137	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417004138	Predicted membrane protein [Function unknown]; Region: COG2510
1042417004139	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
1042417004140	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1042417004141	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1042417004142	metal ion-dependent adhesion site (MIDAS); other site
1042417004143	potential protein location (hypothetical protein BPP43_08150 [Brachyspira pilosicoli P43/6/78]) that overlaps RNA (tRNA-L)
1042417004144	Uncharacterized conserved protein [Function unknown]; Region: COG1543
1042417004145	N-terminal catalytic domain of  alpha-amylase ( AmyC ) and similar proteins; Region: GH57N_AmyC_like; cd10792
1042417004146	active site
1042417004147	substrate binding site [chemical binding]; other site
1042417004148	catalytic site [active]
1042417004149	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
1042417004150	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
1042417004151	active site
1042417004152	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1042417004153	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1042417004154	Mg2+ binding site [ion binding]; other site
1042417004155	G-X-G motif; other site
1042417004156	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004157	binding surface
1042417004158	TPR motif; other site
1042417004159	TPR repeat; Region: TPR_11; pfam13414
1042417004160	TPR repeat; Region: TPR_11; pfam13414
1042417004161	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004162	binding surface
1042417004163	TPR motif; other site
1042417004164	TPR repeat; Region: TPR_11; pfam13414
1042417004165	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004166	binding surface
1042417004167	TPR repeat; Region: TPR_11; pfam13414
1042417004168	TPR motif; other site
1042417004169	uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334
1042417004170	Na2 binding site [ion binding]; other site
1042417004171	putative substrate binding site 1 [chemical binding]; other site
1042417004172	Na binding site 1 [ion binding]; other site
1042417004173	putative substrate binding site 2 [chemical binding]; other site
1042417004174	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1042417004175	active site
1042417004176	phosphorylation site [posttranslational modification]
1042417004177	intermolecular recognition site; other site
1042417004178	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1042417004179	dimer interface [polypeptide binding]; other site
1042417004180	phosphorylation site [posttranslational modification]
1042417004181	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1042417004182	ATP binding site [chemical binding]; other site
1042417004183	Mg2+ binding site [ion binding]; other site
1042417004184	G-X-G motif; other site
1042417004185	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1042417004186	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417004187	motif II; other site
1042417004188	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1042417004189	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
1042417004190	NAD(P) binding site [chemical binding]; other site
1042417004191	homodimer interface [polypeptide binding]; other site
1042417004192	substrate binding site [chemical binding]; other site
1042417004193	active site
1042417004194	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1042417004195	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1042417004196	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1042417004197	shikimate binding site; other site
1042417004198	NAD(P) binding site [chemical binding]; other site
1042417004199	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1042417004200	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1042417004201	active site
1042417004202	catalytic residue [active]
1042417004203	dimer interface [polypeptide binding]; other site
1042417004204	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
1042417004205	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
1042417004206	putative active site [active]
1042417004207	PhoH-like protein; Region: PhoH; pfam02562
1042417004208	potential frameshift: common BLAST hit: gi|300870985|ref|YP_003785856.1| acetyltransferase isoleucine patch superfamily protein
1042417004209	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1042417004210	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1042417004211	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1042417004212	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1042417004213	dimerization interface [polypeptide binding]; other site
1042417004214	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004215	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417004216	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1042417004217	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
1042417004218	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1042417004219	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1042417004220	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1042417004221	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1042417004222	flagellar basal-body rod protein FlgB; Region: FlgB; TIGR01396
1042417004223	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1042417004224	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1042417004225	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417004226	homodimer interface [polypeptide binding]; other site
1042417004227	catalytic residue [active]
1042417004228	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1042417004229	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417004230	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1042417004231	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1042417004232	Predicted ATPases [General function prediction only]; Region: COG1106
1042417004233	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417004234	Walker A/P-loop; other site
1042417004235	ATP binding site [chemical binding]; other site
1042417004236	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1042417004237	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1042417004238	purine monophosphate binding site [chemical binding]; other site
1042417004239	dimer interface [polypeptide binding]; other site
1042417004240	putative catalytic residues [active]
1042417004241	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1042417004242	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1042417004243	peroxiredoxin; Region: AhpC; TIGR03137
1042417004244	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1042417004245	dimer interface [polypeptide binding]; other site
1042417004246	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1042417004247	catalytic triad [active]
1042417004248	peroxidatic and resolving cysteines [active]
1042417004249	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1042417004250	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1042417004251	Domain of unknown function (DUF4340); Region: DUF4340; pfam14238
1042417004252	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1042417004253	active site
1042417004254	Zn binding site [ion binding]; other site
1042417004255	flagellin; Provisional; Region: PRK12804
1042417004256	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1042417004257	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1042417004258	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
1042417004259	Cell division protein ZapA; Region: ZapA; pfam05164
1042417004260	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1042417004261	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417004262	S-adenosylmethionine binding site [chemical binding]; other site
1042417004263	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1042417004264	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1042417004265	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06665
1042417004266	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1042417004267	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1042417004268	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417004269	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417004270	dimer interface [polypeptide binding]; other site
1042417004271	putative CheW interface [polypeptide binding]; other site
1042417004272	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1042417004273	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1042417004274	putative active site [active]
1042417004275	catalytic triad [active]
1042417004276	putative dimer interface [polypeptide binding]; other site
1042417004277	Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain [Cell motility and secretion / Signal transduction mechanisms]; Region: CheB; COG2201
1042417004278	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417004279	active site
1042417004280	phosphorylation site [posttranslational modification]
1042417004281	intermolecular recognition site; other site
1042417004282	CheB methylesterase; Region: CheB_methylest; pfam01339
1042417004283	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
1042417004284	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1042417004285	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1042417004286	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1042417004287	Ligand binding site; other site
1042417004288	Putative Catalytic site; other site
1042417004289	DXD motif; other site
1042417004290	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1042417004291	extended (e) SDRs; Region: SDR_e; cd08946
1042417004292	NAD(P) binding site [chemical binding]; other site
1042417004293	active site
1042417004294	substrate binding site [chemical binding]; other site
1042417004295	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
1042417004296	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1042417004297	PYR/PP interface [polypeptide binding]; other site
1042417004298	dimer interface [polypeptide binding]; other site
1042417004299	TPP binding site [chemical binding]; other site
1042417004300	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1042417004301	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1042417004302	TPP-binding site [chemical binding]; other site
1042417004303	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1042417004304	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1042417004305	inhibitor-cofactor binding pocket; inhibition site
1042417004306	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417004307	catalytic residue [active]
1042417004308	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1042417004309	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1042417004310	NAD(P) binding site [chemical binding]; other site
1042417004311	active site
1042417004312	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1042417004313	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1042417004314	substrate binding site; other site
1042417004315	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1042417004316	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1042417004317	Ligand binding site; other site
1042417004318	Putative Catalytic site; other site
1042417004319	DXD motif; other site
1042417004320	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1042417004321	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417004322	S-adenosylmethionine binding site [chemical binding]; other site
1042417004323	potential frameshift: common BLAST hit: gi|300870943|ref|YP_003785814.1| 3-oxoacyl-acyl-carrier protein synthase III
1042417004324	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1042417004325	Part of AAA domain; Region: AAA_19; pfam13245
1042417004326	Family description; Region: UvrD_C_2; pfam13538
1042417004327	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1042417004328	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1042417004329	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1042417004330	NADP(H)-dependent alcohol dehydrogenases; Region: NADP_ADH; cd08285
1042417004331	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1042417004332	tetramer interface [polypeptide binding]; other site
1042417004333	catalytic Zn binding site [ion binding]; other site
1042417004334	NADP binding site [chemical binding]; other site
1042417004335	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
1042417004336	adenylosuccinate lyase; Provisional; Region: PRK07492
1042417004337	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1042417004338	tetramer interface [polypeptide binding]; other site
1042417004339	active site
1042417004340	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1042417004341	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417004342	Coenzyme A binding pocket [chemical binding]; other site
1042417004343	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1042417004344	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1042417004345	Catalytic site [active]
1042417004346	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1042417004347	MutS domain I; Region: MutS_I; pfam01624
1042417004348	MutS domain II; Region: MutS_II; pfam05188
1042417004349	MutS domain III; Region: MutS_III; pfam05192
1042417004350	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1042417004351	Walker A/P-loop; other site
1042417004352	ATP binding site [chemical binding]; other site
1042417004353	Q-loop/lid; other site
1042417004354	ABC transporter signature motif; other site
1042417004355	Walker B; other site
1042417004356	D-loop; other site
1042417004357	H-loop/switch region; other site
1042417004358	hypothetical protein; Provisional; Region: PRK01346
1042417004359	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
1042417004360	Sterol carrier protein domain; Region: SCP2_2; pfam13530
1042417004361	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417004362	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1042417004363	Walker A/P-loop; other site
1042417004364	ATP binding site [chemical binding]; other site
1042417004365	Q-loop/lid; other site
1042417004366	ABC transporter signature motif; other site
1042417004367	Walker B; other site
1042417004368	D-loop; other site
1042417004369	H-loop/switch region; other site
1042417004370	glutamate dehydrogenase; Provisional; Region: PRK09414
1042417004371	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1042417004372	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1042417004373	NAD(P) binding site [chemical binding]; other site
1042417004374	selenophosphate synthetase; Provisional; Region: PRK00943
1042417004375	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1042417004376	dimerization interface [polypeptide binding]; other site
1042417004377	putative ATP binding site [chemical binding]; other site
1042417004378	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
1042417004379	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004380	binding surface
1042417004381	TPR motif; other site
1042417004382	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1042417004383	anti sigma factor interaction site; other site
1042417004384	regulatory phosphorylation site [posttranslational modification]; other site
1042417004385	Methanothermobacter thermautotrophicus Mth212-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Mth212-like_AP-endo; cd09085
1042417004386	active site
1042417004387	putative catalytic site [active]
1042417004388	phosphate binding site A [ion binding]; other site
1042417004389	DNA binding site [nucleotide binding]
1042417004390	metal binding site A [ion binding]; metal-binding site
1042417004391	putative AP binding site [nucleotide binding]; other site
1042417004392	putative metal binding site B [ion binding]; other site
1042417004393	phosphate binding site B [ion binding]; other site
1042417004394	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1042417004395	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1042417004396	Walker A/P-loop; other site
1042417004397	ATP binding site [chemical binding]; other site
1042417004398	Q-loop/lid; other site
1042417004399	ABC transporter signature motif; other site
1042417004400	Walker B; other site
1042417004401	D-loop; other site
1042417004402	H-loop/switch region; other site
1042417004403	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1042417004404	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417004405	dimer interface [polypeptide binding]; other site
1042417004406	conserved gate region; other site
1042417004407	putative PBP binding loops; other site
1042417004408	ABC-ATPase subunit interface; other site
1042417004409	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1042417004410	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1042417004411	substrate binding pocket [chemical binding]; other site
1042417004412	membrane-bound complex binding site; other site
1042417004413	hinge residues; other site
1042417004414	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1042417004415	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1042417004416	substrate binding pocket [chemical binding]; other site
1042417004417	membrane-bound complex binding site; other site
1042417004418	hinge residues; other site
1042417004419	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1042417004420	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1042417004421	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1042417004422	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1042417004423	Hemerythrin; Region: Hemerythrin; cd12107
1042417004424	Fe binding site [ion binding]; other site
1042417004425	potential frameshift: common BLAST hit: gi|300870913|ref|YP_003785784.1| ATP dependent protease HslVU/ClpYQ ATPase subunit
1042417004426	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1042417004427	active site
1042417004428	HslU subunit interaction site [polypeptide binding]; other site
1042417004429	16S rRNA processing protein RimM; Region: 16S_RimM; TIGR02273
1042417004430	RimM N-terminal domain; Region: RimM; pfam01782
1042417004431	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1042417004432	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
1042417004433	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1042417004434	signal recognition particle protein; Provisional; Region: PRK10867
1042417004435	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1042417004436	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1042417004437	P loop; other site
1042417004438	GTP binding site [chemical binding]; other site
1042417004439	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1042417004440	amidophosphoribosyltransferase; Provisional; Region: PRK05793
1042417004441	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1042417004442	active site
1042417004443	tetramer interface [polypeptide binding]; other site
1042417004444	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417004445	active site
1042417004446	FOG: CBS domain [General function prediction only]; Region: COG0517
1042417004447	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1042417004448	Transporter associated domain; Region: CorC_HlyC; smart01091
1042417004449	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
1042417004450	7TM-HD extracellular; Region: 7TMR-HDED; pfam07697
1042417004451	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1042417004452	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417004453	Zn2+ binding site [ion binding]; other site
1042417004454	Mg2+ binding site [ion binding]; other site
1042417004455	PhoH-like protein; Region: PhoH; pfam02562
1042417004456	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1042417004457	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1042417004458	active site
1042417004459	metal binding site [ion binding]; metal-binding site
1042417004460	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1042417004461	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1042417004462	oligomer interface [polypeptide binding]; other site
1042417004463	active site residues [active]
1042417004464	trigger factor; Region: tig; TIGR00115
1042417004465	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1042417004466	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1042417004467	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1042417004468	hinge; other site
1042417004469	active site
1042417004470	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1042417004471	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1042417004472	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1042417004473	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1042417004474	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417004475	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417004476	dimer interface [polypeptide binding]; other site
1042417004477	putative CheW interface [polypeptide binding]; other site
1042417004478	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1042417004479	alanine racemase; Reviewed; Region: alr; PRK00053
1042417004480	active site
1042417004481	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1042417004482	dimer interface [polypeptide binding]; other site
1042417004483	substrate binding site [chemical binding]; other site
1042417004484	catalytic residues [active]
1042417004485	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1042417004486	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1042417004487	Fumarase C-terminus; Region: Fumerase_C; cl00795
1042417004488	fumarate hydratase; Provisional; Region: PRK06246
1042417004489	Uncharacterized protein containing a NRPS condensation (elongation) domain [General function prediction only]; Region: COG4908
1042417004490	H+ Antiporter protein; Region: 2A0121; TIGR00900
1042417004491	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1042417004492	Fijivirus 64 kDa capsid protein; Region: Fiji_64_capsid; pfam05880
1042417004493	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1042417004494	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417004495	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417004496	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417004497	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1042417004498	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1042417004499	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1042417004500	HlyD family secretion protein; Region: HlyD_3; pfam13437
1042417004501	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1042417004502	Protein export membrane protein; Region: SecD_SecF; cl14618
1042417004503	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
1042417004504	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1042417004505	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1042417004506	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1042417004507	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1042417004508	active site
1042417004509	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; cl00895
1042417004510	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1042417004511	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1042417004512	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1042417004513	G1 box; other site
1042417004514	GTP/Mg2+ binding site [chemical binding]; other site
1042417004515	Switch I region; other site
1042417004516	G2 box; other site
1042417004517	G3 box; other site
1042417004518	Switch II region; other site
1042417004519	G4 box; other site
1042417004520	G5 box; other site
1042417004521	Nucleoside recognition; Region: Gate; pfam07670
1042417004522	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1042417004523	Nucleoside recognition; Region: Gate; pfam07670
1042417004524	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1042417004525	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1042417004526	active site
1042417004527	potential frameshift: common BLAST hit: gi|300870873|ref|YP_003785744.1| glycosyltransferase/CDP-glycerol:poly(glycerophosphate)
1042417004528	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1042417004529	CoenzymeA binding site [chemical binding]; other site
1042417004530	subunit interaction site [polypeptide binding]; other site
1042417004531	PHB binding site; other site
1042417004532	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417004533	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1042417004534	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1042417004535	Part of AAA domain; Region: AAA_19; pfam13245
1042417004536	Family description; Region: UvrD_C_2; pfam13538
1042417004537	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
1042417004538	TPR repeat; Region: TPR_11; pfam13414
1042417004539	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1042417004540	active site
1042417004541	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1042417004542	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1042417004543	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417004544	S-adenosylmethionine binding site [chemical binding]; other site
1042417004545	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
1042417004546	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1042417004547	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1042417004548	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1042417004549	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1042417004550	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1042417004551	homodimer interface [polypeptide binding]; other site
1042417004552	NADP binding site [chemical binding]; other site
1042417004553	substrate binding site [chemical binding]; other site
1042417004554	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1042417004555	metal binding site 2 [ion binding]; metal-binding site
1042417004556	putative DNA binding helix; other site
1042417004557	metal binding site 1 [ion binding]; metal-binding site
1042417004558	dimer interface [polypeptide binding]; other site
1042417004559	structural Zn2+ binding site [ion binding]; other site
1042417004560	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1042417004561	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1042417004562	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1042417004563	HEAT repeats; Region: HEAT_2; pfam13646
1042417004564	HEAT repeats; Region: HEAT_2; pfam13646
1042417004565	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1042417004566	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1042417004567	motif 1; other site
1042417004568	active site
1042417004569	motif 2; other site
1042417004570	motif 3; other site
1042417004571	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1042417004572	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
1042417004573	GDP-Fucose binding site [chemical binding]; other site
1042417004574	potential frameshift: common BLAST hit: gi|300870852|ref|YP_003785723.1| putative glyocosyltransferase protein
1042417004575	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
1042417004576	GDP-Fucose binding site [chemical binding]; other site
1042417004577	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1042417004578	active site residue [active]
1042417004579	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
1042417004580	putative homodimer interface [polypeptide binding]; other site
1042417004581	putative homotetramer interface [polypeptide binding]; other site
1042417004582	putative allosteric switch controlling residues; other site
1042417004583	putative metal binding site [ion binding]; other site
1042417004584	putative homodimer-homodimer interface [polypeptide binding]; other site
1042417004585	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1042417004586	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1042417004587	RecX family; Region: RecX; cl00936
1042417004588	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004589	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004590	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004591	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004592	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1042417004593	Cupin domain; Region: Cupin_2; cl17218
1042417004594	Predicted methyltransferases [General function prediction only]; Region: COG0313
1042417004595	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1042417004596	putative SAM binding site [chemical binding]; other site
1042417004597	putative homodimer interface [polypeptide binding]; other site
1042417004598	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1042417004599	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1042417004600	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1042417004601	DNA binding residues [nucleotide binding]
1042417004602	dimerization interface [polypeptide binding]; other site
1042417004603	Predicted chitinase [General function prediction only]; Region: COG3179
1042417004604	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
1042417004605	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
1042417004606	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
1042417004607	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1042417004608	active site
1042417004609	substrate binding site [chemical binding]; other site
1042417004610	cosubstrate binding site; other site
1042417004611	catalytic site [active]
1042417004612	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1042417004613	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1042417004614	dimerization interface [polypeptide binding]; other site
1042417004615	putative ATP binding site [chemical binding]; other site
1042417004616	flagellin; Provisional; Region: PRK12804
1042417004617	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1042417004618	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1042417004619	hypothetical protein; Validated; Region: PRK00110
1042417004620	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1042417004621	active site
1042417004622	putative DNA-binding cleft [nucleotide binding]; other site
1042417004623	dimer interface [polypeptide binding]; other site
1042417004624	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1042417004625	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1042417004626	Peptidase family U32; Region: Peptidase_U32; pfam01136
1042417004627	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1042417004628	catalytic triad [active]
1042417004629	conserved cis-peptide bond; other site
1042417004630	NAD-dependent deacetylase; Provisional; Region: PRK00481
1042417004631	SIR2 family of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2-fam; cd01407
1042417004632	NAD+ binding site [chemical binding]; other site
1042417004633	substrate binding site [chemical binding]; other site
1042417004634	Zn binding site [ion binding]; other site
1042417004635	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1042417004636	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1042417004637	CoA binding domain; Region: CoA_binding; smart00881
1042417004638	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1042417004639	active site
1042417004640	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417004641	TPR motif; other site
1042417004642	binding surface
1042417004643	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1042417004644	EamA-like transporter family; Region: EamA; cl17759
1042417004645	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004646	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004647	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004648	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004649	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004650	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004651	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004652	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417004653	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417004654	potential frameshift: common BLAST hit: gi|300870794|ref|YP_003785665.1| metal-dependent phosphohydrolase
1042417004655	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cl00304
1042417004656	homodimer interface [polypeptide binding]; other site
1042417004657	active site
1042417004658	SAM binding site [chemical binding]; other site
1042417004659	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1042417004660	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1042417004661	amidase catalytic site [active]
1042417004662	Zn binding residues [ion binding]; other site
1042417004663	substrate binding site [chemical binding]; other site
1042417004664	CHAT domain; Region: CHAT; cl17868
1042417004665	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_3; cd08770
1042417004666	SxDxEG motif; other site
1042417004667	putative active site [active]
1042417004668	putative metal binding site [ion binding]; other site
1042417004669	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1042417004670	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1042417004671	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1042417004672	Peptidase family M28; Region: Peptidase_M28; pfam04389
1042417004673	metal binding site [ion binding]; metal-binding site
1042417004674	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1042417004675	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1042417004676	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1042417004677	substrate binding site; other site
1042417004678	dimer interface; other site
1042417004679	Family of unknown function (DUF490); Region: DUF490; pfam04357
1042417004680	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1042417004681	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1042417004682	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1042417004683	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1042417004684	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1042417004685	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1042417004686	Surface antigen; Region: Bac_surface_Ag; pfam01103
1042417004687	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1042417004688	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1042417004689	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1042417004690	RNA binding surface [nucleotide binding]; other site
1042417004691	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1042417004692	active site
1042417004693	Leucine rich repeat; Region: LRR_8; pfam13855
1042417004694	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1042417004695	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1042417004696	active site
1042417004697	substrate binding site [chemical binding]; other site
1042417004698	metal binding site [ion binding]; metal-binding site
1042417004699	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1042417004700	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1042417004701	proposed catalytic triad [active]
1042417004702	conserved cys residue [active]
1042417004703	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417004704	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417004705	peptide binding site [polypeptide binding]; other site
1042417004706	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1042417004707	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1042417004708	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1042417004709	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1042417004710	potential protein location (hypothetical protein BPP43_09340 [Brachyspira pilosicoli P43/6/78]) that overlaps RNA (tRNA-T)
1042417004711	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1042417004712	NeuB family; Region: NeuB; pfam03102
1042417004713	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1042417004714	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1042417004715	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1042417004716	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417004717	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1042417004718	putative substrate translocation pore; other site
1042417004719	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1042417004720	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1042417004721	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
1042417004722	NAD binding site [chemical binding]; other site
1042417004723	putative substrate binding site 2 [chemical binding]; other site
1042417004724	putative substrate binding site 1 [chemical binding]; other site
1042417004725	active site
1042417004726	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1042417004727	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1042417004728	NAD(P) binding site [chemical binding]; other site
1042417004729	active site
1042417004730	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1042417004731	nicotinamide-nucleotide adenylyltransferase, NadR type; Region: nadR_NMN_Atrans; TIGR01526
1042417004732	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1042417004733	active site
1042417004734	nucleotide binding site [chemical binding]; other site
1042417004735	HIGH motif; other site
1042417004736	KMSKS motif; other site
1042417004737	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1042417004738	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417004739	Zn2+ binding site [ion binding]; other site
1042417004740	Mg2+ binding site [ion binding]; other site
1042417004741	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
1042417004742	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1042417004743	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
1042417004744	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1042417004745	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1042417004746	dimerization interface [polypeptide binding]; other site
1042417004747	ATP binding site [chemical binding]; other site
1042417004748	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1042417004749	dimerization interface [polypeptide binding]; other site
1042417004750	ATP binding site [chemical binding]; other site
1042417004751	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1042417004752	putative active site [active]
1042417004753	catalytic triad [active]
1042417004754	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417004755	peptide binding site [polypeptide binding]; other site
1042417004756	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1042417004757	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
1042417004758	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
1042417004759	dimer interface [polypeptide binding]; other site
1042417004760	active site residues [active]
1042417004761	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1042417004762	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1042417004763	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1042417004764	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1042417004765	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1042417004766	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1042417004767	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1042417004768	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1042417004769	Protein export membrane protein; Region: SecD_SecF; cl14618
1042417004770	Outer membrane efflux protein; Region: OEP; pfam02321
1042417004771	Outer membrane efflux protein; Region: OEP; pfam02321
1042417004772	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1042417004773	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417004774	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1042417004775	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1042417004776	ATP binding site [chemical binding]; other site
1042417004777	active site
1042417004778	substrate binding site [chemical binding]; other site
1042417004779	Late competence development protein ComFB; Region: ComFB; pfam10719
1042417004780	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1042417004781	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1042417004782	interface (dimer of trimers) [polypeptide binding]; other site
1042417004783	Substrate-binding/catalytic site; other site
1042417004784	Zn-binding sites [ion binding]; other site
1042417004785	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1042417004786	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1042417004787	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1042417004788	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1042417004789	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1042417004790	putative substrate binding site [chemical binding]; other site
1042417004791	putative ATP binding site [chemical binding]; other site
1042417004792	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1042417004793	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1042417004794	active site
1042417004795	phosphorylation site [posttranslational modification]
1042417004796	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1042417004797	active site
1042417004798	P-loop; other site
1042417004799	phosphorylation site [posttranslational modification]
1042417004800	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
1042417004801	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1042417004802	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1042417004803	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417004804	Walker A/P-loop; other site
1042417004805	ATP binding site [chemical binding]; other site
1042417004806	Q-loop/lid; other site
1042417004807	ABC transporter signature motif; other site
1042417004808	Walker B; other site
1042417004809	D-loop; other site
1042417004810	H-loop/switch region; other site
1042417004811	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1042417004812	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1042417004813	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417004814	Walker A/P-loop; other site
1042417004815	ATP binding site [chemical binding]; other site
1042417004816	Q-loop/lid; other site
1042417004817	ABC transporter signature motif; other site
1042417004818	Walker B; other site
1042417004819	D-loop; other site
1042417004820	H-loop/switch region; other site
1042417004821	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1042417004822	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1042417004823	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832
1042417004824	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1042417004825	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1042417004826	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1042417004827	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1042417004828	Protein of unknown function (DUF454); Region: DUF454; cl01063
1042417004829	Nitrous oxide-stimulated promoter; Region: YgbA_NO; cl08119
1042417004830	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
1042417004831	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1042417004832	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1042417004833	active site
1042417004834	HIGH motif; other site
1042417004835	KMSK motif region; other site
1042417004836	tRNA binding surface [nucleotide binding]; other site
1042417004837	DALR anticodon binding domain; Region: DALR_1; smart00836
1042417004838	anticodon binding site; other site
1042417004839	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1042417004840	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1042417004841	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1042417004842	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1042417004843	metal ion-dependent adhesion site (MIDAS); other site
1042417004844	MoxR-like ATPases [General function prediction only]; Region: COG0714
1042417004845	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417004846	Walker A motif; other site
1042417004847	ATP binding site [chemical binding]; other site
1042417004848	Walker B motif; other site
1042417004849	arginine finger; other site
1042417004850	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004851	binding surface
1042417004852	TPR motif; other site
1042417004853	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417004854	TPR motif; other site
1042417004855	binding surface
1042417004856	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1042417004857	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1042417004858	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1042417004859	active site
1042417004860	intersubunit interactions; other site
1042417004861	catalytic residue [active]
1042417004862	Oxygen tolerance; Region: BatD; pfam13584
1042417004863	MoxR-like ATPases [General function prediction only]; Region: COG0714
1042417004864	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417004865	Walker A motif; other site
1042417004866	ATP binding site [chemical binding]; other site
1042417004867	Walker B motif; other site
1042417004868	arginine finger; other site
1042417004869	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1042417004870	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1042417004871	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1042417004872	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1042417004873	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1042417004874	TPP-binding site [chemical binding]; other site
1042417004875	dimer interface [polypeptide binding]; other site
1042417004876	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1042417004877	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1042417004878	PYR/PP interface [polypeptide binding]; other site
1042417004879	dimer interface [polypeptide binding]; other site
1042417004880	TPP binding site [chemical binding]; other site
1042417004881	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1042417004882	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1042417004883	active site
1042417004884	phosphorylation site [posttranslational modification]
1042417004885	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1042417004886	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1042417004887	active site
1042417004888	P-loop; other site
1042417004889	phosphorylation site [posttranslational modification]
1042417004890	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1042417004891	Transglycosylase; Region: Transgly; pfam00912
1042417004892	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1042417004893	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1042417004894	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1042417004895	heterotetramer interface [polypeptide binding]; other site
1042417004896	active site pocket [active]
1042417004897	cleavage site
1042417004898	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1042417004899	NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179
1042417004900	putative active site [active]
1042417004901	metal binding site [ion binding]; metal-binding site
1042417004902	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1042417004903	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1042417004904	Ligand binding site; other site
1042417004905	metal-binding site
1042417004906	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1042417004907	Protein of unknown function (DUF4241); Region: DUF4241; pfam14025
1042417004908	Chorismate mutase type II; Region: CM_2; smart00830
1042417004909	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1042417004910	Prephenate dehydratase; Region: PDT; pfam00800
1042417004911	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1042417004912	putative L-Phe binding site [chemical binding]; other site
1042417004913	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1042417004914	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1042417004915	ADP binding site [chemical binding]; other site
1042417004916	magnesium binding site [ion binding]; other site
1042417004917	putative shikimate binding site; other site
1042417004918	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1042417004919	active site
1042417004920	dimer interface [polypeptide binding]; other site
1042417004921	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417004922	active site
1042417004923	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1042417004924	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1042417004925	heterodimer interface [polypeptide binding]; other site
1042417004926	active site
1042417004927	FMN binding site [chemical binding]; other site
1042417004928	homodimer interface [polypeptide binding]; other site
1042417004929	substrate binding site [chemical binding]; other site
1042417004930	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1042417004931	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1042417004932	FAD binding pocket [chemical binding]; other site
1042417004933	FAD binding motif [chemical binding]; other site
1042417004934	phosphate binding motif [ion binding]; other site
1042417004935	beta-alpha-beta structure motif; other site
1042417004936	NAD binding pocket [chemical binding]; other site
1042417004937	Iron coordination center [ion binding]; other site
1042417004938	DinB family; Region: DinB; cl17821
1042417004939	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1042417004940	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1042417004941	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1042417004942	active site
1042417004943	HIGH motif; other site
1042417004944	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1042417004945	KMSKS motif; other site
1042417004946	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1042417004947	Predicted exonuclease [DNA replication, recombination, and repair]; Region: COG3359
1042417004948	RNase_H superfamily; Region: RNase_H_2; pfam13482
1042417004949	active site
1042417004950	substrate binding site [chemical binding]; other site
1042417004951	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1042417004952	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1042417004953	active site
1042417004954	NAD binding site [chemical binding]; other site
1042417004955	metal binding site [ion binding]; metal-binding site
1042417004956	MoxR-like ATPases [General function prediction only]; Region: COG0714
1042417004957	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
1042417004958	elongation factor P; Validated; Region: PRK00529
1042417004959	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1042417004960	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1042417004961	RNA binding site [nucleotide binding]; other site
1042417004962	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1042417004963	RNA binding site [nucleotide binding]; other site
1042417004964	Response regulator receiver domain; Region: Response_reg; pfam00072
1042417004965	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417004966	active site
1042417004967	phosphorylation site [posttranslational modification]
1042417004968	intermolecular recognition site; other site
1042417004969	dimerization interface [polypeptide binding]; other site
1042417004970	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1042417004971	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1042417004972	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1042417004973	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1042417004974	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417004975	TPR motif; other site
1042417004976	binding surface
1042417004977	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417004978	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417004979	binding surface
1042417004980	TPR motif; other site
1042417004981	TPR repeat; Region: TPR_11; pfam13414
1042417004982	rod shape-determining protein MreB; Provisional; Region: PRK13927
1042417004983	MreB and similar proteins; Region: MreB_like; cd10225
1042417004984	nucleotide binding site [chemical binding]; other site
1042417004985	Mg binding site [ion binding]; other site
1042417004986	putative protofilament interaction site [polypeptide binding]; other site
1042417004987	RodZ interaction site [polypeptide binding]; other site
1042417004988	rod shape-determining protein MreC; Provisional; Region: PRK13922
1042417004989	rod shape-determining protein MreC; Region: MreC; pfam04085
1042417004990	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1042417004991	putative active site [active]
1042417004992	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
1042417004993	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1042417004994	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1042417004995	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1042417004996	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1042417004997	ApbE family; Region: ApbE; pfam02424
1042417004998	TonB C terminal; Region: TonB_2; pfam13103
1042417004999	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417005000	active site
1042417005001	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1042417005002	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1042417005003	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1042417005004	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1042417005005	Ligand binding site [chemical binding]; other site
1042417005006	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1042417005007	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1042417005008	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1042417005009	FAD binding site [chemical binding]; other site
1042417005010	homotetramer interface [polypeptide binding]; other site
1042417005011	substrate binding pocket [chemical binding]; other site
1042417005012	catalytic base [active]
1042417005013	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1042417005014	active site 2 [active]
1042417005015	active site 1 [active]
1042417005016	V-type ATP synthase subunit E; Provisional; Region: PRK01005
1042417005017	V-type ATP synthase subunit E; Provisional; Region: PRK01558
1042417005018	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
1042417005019	V-type ATP synthase subunit A; Provisional; Region: PRK04192
1042417005020	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1042417005021	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
1042417005022	Walker A motif/ATP binding site; other site
1042417005023	Walker B motif; other site
1042417005024	V-type ATP synthase subunit B; Provisional; Region: PRK02118
1042417005025	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
1042417005026	Walker A motif homologous position; other site
1042417005027	Walker B motif; other site
1042417005028	potential frameshift: common BLAST hit: gi|300870655|ref|YP_003785526.1| V-type ATP synthase subunit D
1042417005029	V-type ATP synthase subunit I; Validated; Region: PRK05771
1042417005030	Protein of unknown function, DUF600; Region: DUF600; cl04640
1042417005031	V-type ATP synthase subunit K; Validated; Region: PRK06558
1042417005032	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
1042417005033	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1042417005034	S17 interaction site [polypeptide binding]; other site
1042417005035	S8 interaction site; other site
1042417005036	16S rRNA interaction site [nucleotide binding]; other site
1042417005037	streptomycin interaction site [chemical binding]; other site
1042417005038	23S rRNA interaction site [nucleotide binding]; other site
1042417005039	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1042417005040	30S ribosomal protein S7; Validated; Region: PRK05302
1042417005041	elongation factor G; Reviewed; Region: PRK00007
1042417005042	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1042417005043	G1 box; other site
1042417005044	putative GEF interaction site [polypeptide binding]; other site
1042417005045	GTP/Mg2+ binding site [chemical binding]; other site
1042417005046	Switch I region; other site
1042417005047	G2 box; other site
1042417005048	G3 box; other site
1042417005049	Switch II region; other site
1042417005050	G4 box; other site
1042417005051	G5 box; other site
1042417005052	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1042417005053	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1042417005054	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1042417005055	elongation factor Tu; Reviewed; Region: PRK00049
1042417005056	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1042417005057	G1 box; other site
1042417005058	GEF interaction site [polypeptide binding]; other site
1042417005059	GTP/Mg2+ binding site [chemical binding]; other site
1042417005060	Switch I region; other site
1042417005061	G2 box; other site
1042417005062	G3 box; other site
1042417005063	Switch II region; other site
1042417005064	G4 box; other site
1042417005065	G5 box; other site
1042417005066	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1042417005067	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1042417005068	Antibiotic Binding Site [chemical binding]; other site
1042417005069	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1042417005070	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1042417005071	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1042417005072	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1042417005073	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1042417005074	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1042417005075	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1042417005076	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1042417005077	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1042417005078	putative translocon binding site; other site
1042417005079	protein-rRNA interface [nucleotide binding]; other site
1042417005080	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1042417005081	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1042417005082	G-X-X-G motif; other site
1042417005083	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1042417005084	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1042417005085	23S rRNA interface [nucleotide binding]; other site
1042417005086	5S rRNA interface [nucleotide binding]; other site
1042417005087	putative antibiotic binding site [chemical binding]; other site
1042417005088	L25 interface [polypeptide binding]; other site
1042417005089	L27 interface [polypeptide binding]; other site
1042417005090	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1042417005091	L23 interface [polypeptide binding]; other site
1042417005092	trigger factor interaction site; other site
1042417005093	23S rRNA interface [nucleotide binding]; other site
1042417005094	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1042417005095	Ribosomal protein L14p/L23e; Region: Ribosomal_L14; cl00328
1042417005096	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1042417005097	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1042417005098	RNA binding site [nucleotide binding]; other site
1042417005099	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1042417005100	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1042417005101	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1042417005102	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
1042417005103	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1042417005104	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1042417005105	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1042417005106	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1042417005107	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1042417005108	5S rRNA interface [nucleotide binding]; other site
1042417005109	23S rRNA interface [nucleotide binding]; other site
1042417005110	L5 interface [polypeptide binding]; other site
1042417005111	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1042417005112	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1042417005113	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1042417005114	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1042417005115	23S rRNA binding site [nucleotide binding]; other site
1042417005116	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1042417005117	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1042417005118	SecY translocase; Region: SecY; pfam00344
1042417005119	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1042417005120	rRNA binding site [nucleotide binding]; other site
1042417005121	predicted 30S ribosome binding site; other site
1042417005122	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1042417005123	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1042417005124	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1042417005125	30S ribosomal protein S11; Validated; Region: PRK05309
1042417005126	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1042417005127	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1042417005128	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1042417005129	RNA binding surface [nucleotide binding]; other site
1042417005130	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1042417005131	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1042417005132	alphaNTD - beta interaction site [polypeptide binding]; other site
1042417005133	alphaNTD homodimer interface [polypeptide binding]; other site
1042417005134	alphaNTD - beta' interaction site [polypeptide binding]; other site
1042417005135	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1042417005136	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1042417005137	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1042417005138	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1042417005139	RNA binding site [nucleotide binding]; other site
1042417005140	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1042417005141	Walker A motif; other site
1042417005142	ATP binding site [chemical binding]; other site
1042417005143	Walker B motif; other site
1042417005144	Smr domain; Region: Smr; pfam01713
1042417005145	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1042417005146	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417005147	Walker A motif; other site
1042417005148	ATP binding site [chemical binding]; other site
1042417005149	Walker B motif; other site
1042417005150	arginine finger; other site
1042417005151	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1042417005152	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
1042417005153	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1042417005154	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1042417005155	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
1042417005156	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1042417005157	carboxyltransferase (CT) interaction site; other site
1042417005158	biotinylation site [posttranslational modification]; other site
1042417005159	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
1042417005160	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1042417005161	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1042417005162	substrate binding pocket [chemical binding]; other site
1042417005163	membrane-bound complex binding site; other site
1042417005164	hinge residues; other site
1042417005165	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1042417005166	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1042417005167	substrate binding pocket [chemical binding]; other site
1042417005168	membrane-bound complex binding site; other site
1042417005169	hinge residues; other site
1042417005170	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1042417005171	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1042417005172	substrate binding pocket [chemical binding]; other site
1042417005173	membrane-bound complex binding site; other site
1042417005174	hinge residues; other site
1042417005175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005176	TPR motif; other site
1042417005177	binding surface
1042417005178	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417005179	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005180	binding surface
1042417005181	TPR motif; other site
1042417005182	TPR repeat; Region: TPR_11; pfam13414
1042417005183	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1042417005184	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1042417005185	potential frameshift: common BLAST hit: gi|300870606|ref|YP_003785477.1| prolipoprotein diacylglyceryl transferase
1042417005186	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1042417005187	catalytic core [active]
1042417005188	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1042417005189	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1042417005190	potential frameshift: common BLAST hit: gi|300870602|ref|YP_003785473.1| chromosome partition protein SmC
1042417005191	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
1042417005192	RNB domain; Region: RNB; pfam00773
1042417005193	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1042417005194	RNA binding site [nucleotide binding]; other site
1042417005195	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417005196	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417005197	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
1042417005198	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
1042417005199	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417005200	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417005201	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1042417005202	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1042417005203	active site residue [active]
1042417005204	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
1042417005205	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1042417005206	Domain of unknown function (DUF1850); Region: DUF1850; cl01950
1042417005207	TRAP transporter, 4TM/12TM fusion protein; Region: TRAP_fused; TIGR02123
1042417005208	DctM-like transporters; Region: DctM; pfam06808
1042417005209	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
1042417005210	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1042417005211	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1042417005212	GDP-binding site [chemical binding]; other site
1042417005213	ACT binding site; other site
1042417005214	IMP binding site; other site
1042417005215	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1042417005216	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1042417005217	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417005218	Walker A motif; other site
1042417005219	ATP binding site [chemical binding]; other site
1042417005220	Walker B motif; other site
1042417005221	arginine finger; other site
1042417005222	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1042417005223	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1042417005224	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1042417005225	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417005226	homodimer interface [polypeptide binding]; other site
1042417005227	catalytic residue [active]
1042417005228	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1042417005229	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1042417005230	DNA binding site [nucleotide binding]
1042417005231	domain linker motif; other site
1042417005232	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1042417005233	dimerization interface [polypeptide binding]; other site
1042417005234	ligand binding site [chemical binding]; other site
1042417005235	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1042417005236	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1042417005237	active site turn [active]
1042417005238	phosphorylation site [posttranslational modification]
1042417005239	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1042417005240	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1042417005241	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1042417005242	substrate binding [chemical binding]; other site
1042417005243	active site
1042417005244	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1042417005245	Flagellar protein FliS; Region: FliS; cl00654
1042417005246	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1042417005247	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1042417005248	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1042417005249	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417005250	binding surface
1042417005251	TPR motif; other site
1042417005252	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1042417005253	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1042417005254	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1042417005255	dimer interface [polypeptide binding]; other site
1042417005256	ssDNA binding site [nucleotide binding]; other site
1042417005257	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1042417005258	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1042417005259	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1042417005260	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417005261	ATP binding site [chemical binding]; other site
1042417005262	putative Mg++ binding site [ion binding]; other site
1042417005263	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417005264	nucleotide binding region [chemical binding]; other site
1042417005265	ATP-binding site [chemical binding]; other site
1042417005266	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1042417005267	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1042417005268	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1042417005269	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1042417005270	Ligand binding site; other site
1042417005271	oligomer interface; other site
1042417005272	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1042417005273	active site
1042417005274	phosphorylation site [posttranslational modification]
1042417005275	Uncharacterized conserved protein [Function unknown]; Region: COG3339
1042417005276	aspartate kinase; Reviewed; Region: PRK09034
1042417005277	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1042417005278	nucleotide binding site [chemical binding]; other site
1042417005279	substrate binding site [chemical binding]; other site
1042417005280	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
1042417005281	allosteric regulatory residue; other site
1042417005282	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
1042417005283	monogalactosyldiacylglycerol synthase; Region: PLN02605
1042417005284	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1042417005285	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1042417005286	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1042417005287	dimerization interface [polypeptide binding]; other site
1042417005288	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417005289	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417005290	dimer interface [polypeptide binding]; other site
1042417005291	putative CheW interface [polypeptide binding]; other site
1042417005292	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
1042417005293	pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional; Region: PRK14028
1042417005294	4Fe-4S binding domain; Region: Fer4; cl02805
1042417005295	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
1042417005296	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1042417005297	dimer interface [polypeptide binding]; other site
1042417005298	PYR/PP interface [polypeptide binding]; other site
1042417005299	TPP binding site [chemical binding]; other site
1042417005300	substrate binding site [chemical binding]; other site
1042417005301	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
1042417005302	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
1042417005303	TPP-binding site [chemical binding]; other site
1042417005304	putative dimer interface [polypeptide binding]; other site
1042417005305	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1042417005306	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1042417005307	active site
1042417005308	HIGH motif; other site
1042417005309	KMSKS motif; other site
1042417005310	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1042417005311	tRNA binding surface [nucleotide binding]; other site
1042417005312	anticodon binding site; other site
1042417005313	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1042417005314	dimer interface [polypeptide binding]; other site
1042417005315	putative tRNA-binding site [nucleotide binding]; other site
1042417005316	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1042417005317	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1042417005318	hypothetical protein; Region: PHA00684
1042417005319	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
1042417005320	gating phenylalanine in ion channel; other site
1042417005321	potential frameshift: common BLAST hit: gi|300870556|ref|YP_003785427.1| methyltransferase
1042417005322	cyclically-permuted mutarotase family protein; Region: mutarot_permut; TIGR03548
1042417005323	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1042417005324	Na binding site [ion binding]; other site
1042417005325	Domain of unknown function (DUF386); Region: DUF386; cl01047
1042417005326	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1042417005327	Class I aldolases; Region: Aldolase_Class_I; cl17187
1042417005328	catalytic residue [active]
1042417005329	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
1042417005330	catalytic site [active]
1042417005331	BNR repeat-like domain; Region: BNR_2; pfam13088
1042417005332	Asp-box motif; other site
1042417005333	Serpulina hyodysenteriae variable surface protein; Region: Serpulina_VSP; pfam05540
1042417005334	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
1042417005335	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
1042417005336	dimerization interface [polypeptide binding]; other site
1042417005337	putative active cleft [active]
1042417005338	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005339	binding surface
1042417005340	TPR motif; other site
1042417005341	TPR repeat; Region: TPR_11; pfam13414
1042417005342	TPR repeat; Region: TPR_11; pfam13414
1042417005343	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005344	binding surface
1042417005345	TPR motif; other site
1042417005346	TPR repeat; Region: TPR_11; pfam13414
1042417005347	TPR repeat; Region: TPR_11; pfam13414
1042417005348	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005349	binding surface
1042417005350	TPR motif; other site
1042417005351	TPR repeat; Region: TPR_11; pfam13414
1042417005352	TPR repeat; Region: TPR_11; pfam13414
1042417005353	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005354	binding surface
1042417005355	TPR motif; other site
1042417005356	TPR repeat; Region: TPR_11; pfam13414
1042417005357	TPR repeat; Region: TPR_11; pfam13414
1042417005358	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005359	binding surface
1042417005360	TPR motif; other site
1042417005361	TPR repeat; Region: TPR_11; pfam13414
1042417005362	TPR repeat; Region: TPR_11; pfam13414
1042417005363	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005364	binding surface
1042417005365	TPR motif; other site
1042417005366	TPR repeat; Region: TPR_11; pfam13414
1042417005367	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1042417005368	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
1042417005369	NADPH bind site [chemical binding]; other site
1042417005370	putative FMN binding site [chemical binding]; other site
1042417005371	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
1042417005372	YcaO-like family; Region: YcaO; pfam02624
1042417005373	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
1042417005374	potential frameshift: common BLAST hit: gi|300870544|ref|YP_003785415.1| CAAX amino terminal protease family protein
1042417005375	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1042417005376	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1042417005377	Walker A/P-loop; other site
1042417005378	ATP binding site [chemical binding]; other site
1042417005379	Q-loop/lid; other site
1042417005380	ABC transporter signature motif; other site
1042417005381	Walker B; other site
1042417005382	D-loop; other site
1042417005383	H-loop/switch region; other site
1042417005384	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1042417005385	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1042417005386	Predicted transcriptional regulators [Transcription]; Region: COG1695
1042417005387	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1042417005388	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1042417005389	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1042417005390	Walker A/P-loop; other site
1042417005391	ATP binding site [chemical binding]; other site
1042417005392	Q-loop/lid; other site
1042417005393	ABC transporter signature motif; other site
1042417005394	Walker B; other site
1042417005395	D-loop; other site
1042417005396	H-loop/switch region; other site
1042417005397	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1042417005398	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1042417005399	FtsX-like permease family; Region: FtsX; pfam02687
1042417005400	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1042417005401	MgtE intracellular N domain; Region: MgtE_N; smart00924
1042417005402	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1042417005403	Divalent cation transporter; Region: MgtE; pfam01769
1042417005404	6-phosphofructokinase; Provisional; Region: PRK03202
1042417005405	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1042417005406	active site
1042417005407	ADP/pyrophosphate binding site [chemical binding]; other site
1042417005408	dimerization interface [polypeptide binding]; other site
1042417005409	allosteric effector site; other site
1042417005410	fructose-1,6-bisphosphate binding site; other site
1042417005411	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1042417005412	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
1042417005413	potential frameshift: common BLAST hit: gi|300870523|ref|YP_003785394.1| integral membrane protein MviN putative virulence factor
1042417005414	potential frameshift: common BLAST hit: gi|300870522|ref|YP_003785393.1| methyl-accepting chemotaxis protein B
1042417005415	Rod binding protein; Region: Rod-binding; pfam10135
1042417005416	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1042417005417	histidinol-phosphatase; Reviewed; Region: PRK08123
1042417005418	active site
1042417005419	dimer interface [polypeptide binding]; other site
1042417005420	potential frameshift: common BLAST hit: gi|300870519|ref|YP_003785390.1| pyruvate phosphate dikinase
1042417005421	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1042417005422	active site
1042417005423	motif I; other site
1042417005424	motif II; other site
1042417005425	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
1042417005426	active site
1042417005427	catalytic residues [active]
1042417005428	Haemolysin-III related; Region: HlyIII; cl03831
1042417005429	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1042417005430	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1042417005431	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1042417005432	acyl-activating enzyme (AAE) consensus motif; other site
1042417005433	AMP binding site [chemical binding]; other site
1042417005434	active site
1042417005435	CoA binding site [chemical binding]; other site
1042417005436	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417005437	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417005438	active site
1042417005439	catalytic tetrad [active]
1042417005440	Chloramphenicol acetyltransferase; Region: CAT; cl02008
1042417005441	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1042417005442	Protein of unknown function DUF115; Region: MAF_flag10; pfam01973
1042417005443	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1042417005444	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1042417005445	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1042417005446	putative active site [active]
1042417005447	substrate binding site [chemical binding]; other site
1042417005448	putative cosubstrate binding site; other site
1042417005449	catalytic site [active]
1042417005450	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1042417005451	substrate binding site [chemical binding]; other site
1042417005452	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1042417005453	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1042417005454	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1042417005455	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417005456	S-adenosylmethionine binding site [chemical binding]; other site
1042417005457	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1042417005458	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1042417005459	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1042417005460	putative ribose interaction site [chemical binding]; other site
1042417005461	putative ADP binding site [chemical binding]; other site
1042417005462	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1042417005463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417005464	putative substrate translocation pore; other site
1042417005465	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417005466	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417005467	peptide binding site [polypeptide binding]; other site
1042417005468	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1042417005469	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1042417005470	AAA domain; Region: AAA_21; pfam13304
1042417005471	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1042417005472	Q-loop/lid; other site
1042417005473	ABC transporter signature motif; other site
1042417005474	Walker B; other site
1042417005475	D-loop; other site
1042417005476	H-loop/switch region; other site
1042417005477	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1042417005478	active site
1042417005479	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1042417005480	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1042417005481	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1042417005482	trimer interface [polypeptide binding]; other site
1042417005483	active site
1042417005484	substrate binding site [chemical binding]; other site
1042417005485	CoA binding site [chemical binding]; other site
1042417005486	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1042417005487	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1042417005488	dimer interface [polypeptide binding]; other site
1042417005489	active site
1042417005490	metal binding site [ion binding]; metal-binding site
1042417005491	YceG-like family; Region: YceG; pfam02618
1042417005492	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1042417005493	dimerization interface [polypeptide binding]; other site
1042417005494	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
1042417005495	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
1042417005496	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1042417005497	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417005498	DNA binding residues [nucleotide binding]
1042417005499	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1042417005500	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1042417005501	Sulfatase; Region: Sulfatase; pfam00884
1042417005502	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1042417005503	Sulfatase; Region: Sulfatase; pfam00884
1042417005504	Sulfatase; Region: Sulfatase; cl17466
1042417005505	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1042417005506	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1042417005507	Sulfatase; Region: Sulfatase; pfam00884
1042417005508	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1042417005509	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1042417005510	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417005511	FeS/SAM binding site; other site
1042417005512	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1042417005513	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1042417005514	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
1042417005515	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1042417005516	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1042417005517	Na binding site [ion binding]; other site
1042417005518	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1042417005519	Peptidase family M23; Region: Peptidase_M23; pfam01551
1042417005520	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1042417005521	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1042417005522	Walker A motif; other site
1042417005523	ATP binding site [chemical binding]; other site
1042417005524	Walker B motif; other site
1042417005525	arginine finger; other site
1042417005526	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1042417005527	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005528	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005529	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005530	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005531	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005532	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005533	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005534	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005535	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005536	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005537	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005538	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005539	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005540	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
1042417005541	RNB domain; Region: RNB; pfam00773
1042417005542	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1042417005543	RNA binding site [nucleotide binding]; other site
1042417005544	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
1042417005545	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1042417005546	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1042417005547	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1042417005548	putative active site [active]
1042417005549	catalytic site [active]
1042417005550	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1042417005551	putative active site [active]
1042417005552	catalytic site [active]
1042417005553	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1042417005554	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1042417005555	putative active site [active]
1042417005556	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1042417005557	hypothetical protein; Reviewed; Region: PRK12497
1042417005558	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417005559	Zn2+ binding site [ion binding]; other site
1042417005560	Mg2+ binding site [ion binding]; other site
1042417005561	potential frameshift: common BLAST hit: gi|300870471|ref|YP_003785342.1| flagellar biosynthesis protein FlhB
1042417005562	potential frameshift: common BLAST hit: gi|300870469|ref|YP_003785340.1| ribonuclease HII
1042417005563	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
1042417005564	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
1042417005565	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1042417005566	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1042417005567	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1042417005568	Rubrerythrin [Energy production and conversion]; Region: COG1592
1042417005569	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1042417005570	binuclear metal center [ion binding]; other site
1042417005571	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1042417005572	iron binding site [ion binding]; other site
1042417005573	rarD protein; Region: rarD; TIGR00688
1042417005574	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1042417005575	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1042417005576	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1042417005577	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1042417005578	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
1042417005579	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
1042417005580	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1042417005581	TrkA-N domain; Region: TrkA_N; pfam02254
1042417005582	TrkA-C domain; Region: TrkA_C; pfam02080
1042417005583	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1042417005584	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1042417005585	NAD(P) binding site [chemical binding]; other site
1042417005586	active site
1042417005587	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1042417005588	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1042417005589	putative acyl-acceptor binding pocket; other site
1042417005590	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1042417005591	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1042417005592	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1042417005593	protein binding site [polypeptide binding]; other site
1042417005594	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1042417005595	protein binding site [polypeptide binding]; other site
1042417005596	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1042417005597	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1042417005598	dimerization interface 3.5A [polypeptide binding]; other site
1042417005599	active site
1042417005600	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1042417005601	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1042417005602	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1042417005603	23S rRNA interface [nucleotide binding]; other site
1042417005604	L3 interface [polypeptide binding]; other site
1042417005605	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1042417005606	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
1042417005607	primosome assembly protein PriA; Validated; Region: PRK05580
1042417005608	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417005609	ATP binding site [chemical binding]; other site
1042417005610	putative Mg++ binding site [ion binding]; other site
1042417005611	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417005612	ATP-binding site [chemical binding]; other site
1042417005613	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1042417005614	DNA binding residues [nucleotide binding]
1042417005615	Response regulator receiver domain; Region: Response_reg; pfam00072
1042417005616	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417005617	active site
1042417005618	phosphorylation site [posttranslational modification]
1042417005619	intermolecular recognition site; other site
1042417005620	dimerization interface [polypeptide binding]; other site
1042417005621	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1042417005622	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1042417005623	nucleotide binding pocket [chemical binding]; other site
1042417005624	K-X-D-G motif; other site
1042417005625	catalytic site [active]
1042417005626	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1042417005627	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1042417005628	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1042417005629	Dimer interface [polypeptide binding]; other site
1042417005630	Uncharacterized conserved protein [Function unknown]; Region: COG4938
1042417005631	Uncharacterized conserved protein [Function unknown]; Region: COG4938
1042417005632	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1042417005633	active site
1042417005634	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417005635	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417005636	peptide binding site [polypeptide binding]; other site
1042417005637	flavodoxin; Provisional; Region: PRK06242
1042417005638	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1042417005639	Peptidase M30; Region: Peptidase_M30; pfam10460
1042417005640	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1042417005641	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1042417005642	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1042417005643	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1042417005644	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1042417005645	dimerization domain swap beta strand [polypeptide binding]; other site
1042417005646	regulatory protein interface [polypeptide binding]; other site
1042417005647	active site
1042417005648	regulatory phosphorylation site [posttranslational modification]; other site
1042417005649	Type III pantothenate kinase; Region: Pan_kinase; pfam03309
1042417005650	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
1042417005651	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1042417005652	active site
1042417005653	NTP binding site [chemical binding]; other site
1042417005654	metal binding triad [ion binding]; metal-binding site
1042417005655	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1042417005656	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417005657	Zn2+ binding site [ion binding]; other site
1042417005658	Mg2+ binding site [ion binding]; other site
1042417005659	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1042417005660	Protein of unknown function (DUF1667); Region: DUF1667; cl17602
1042417005661	Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999
1042417005662	active site
1042417005663	Mn binding site [ion binding]; other site
1042417005664	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1042417005665	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1042417005666	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1042417005667	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1042417005668	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1042417005669	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1042417005670	glycerol kinase; Provisional; Region: glpK; PRK00047
1042417005671	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1042417005672	N- and C-terminal domain interface [polypeptide binding]; other site
1042417005673	active site
1042417005674	MgATP binding site [chemical binding]; other site
1042417005675	catalytic site [active]
1042417005676	metal binding site [ion binding]; metal-binding site
1042417005677	glycerol binding site [chemical binding]; other site
1042417005678	homotetramer interface [polypeptide binding]; other site
1042417005679	homodimer interface [polypeptide binding]; other site
1042417005680	FBP binding site [chemical binding]; other site
1042417005681	protein IIAGlc interface [polypeptide binding]; other site
1042417005682	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1042417005683	amphipathic channel; other site
1042417005684	Asn-Pro-Ala signature motifs; other site
1042417005685	Rubrerythrin [Energy production and conversion]; Region: COG1592
1042417005686	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1042417005687	binuclear metal center [ion binding]; other site
1042417005688	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
1042417005689	iron binding site [ion binding]; other site
1042417005690	seryl-tRNA synthetase; Provisional; Region: PRK05431
1042417005691	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1042417005692	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1042417005693	dimer interface [polypeptide binding]; other site
1042417005694	active site
1042417005695	motif 1; other site
1042417005696	motif 2; other site
1042417005697	motif 3; other site
1042417005698	TfoX N-terminal domain; Region: TfoX_N; cl17592
1042417005699	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1042417005700	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417005701	peptide binding site [polypeptide binding]; other site
1042417005702	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1042417005703	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
1042417005704	inhibitor-cofactor binding pocket; inhibition site
1042417005705	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417005706	catalytic residue [active]
1042417005707	AAA domain; Region: AAA_26; pfam13500
1042417005708	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1042417005709	biotin synthase; Region: bioB; TIGR00433
1042417005710	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1042417005711	FeS/SAM binding site; other site
1042417005712	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1042417005713	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1042417005714	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1042417005715	potential frameshift: common BLAST hit: gi|300870418|ref|YP_003785289.1| MATE efflux family protein
1042417005716	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1042417005717	TPR repeat; Region: TPR_11; pfam13414
1042417005718	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005719	binding surface
1042417005720	TPR motif; other site
1042417005721	TPR repeat; Region: TPR_11; pfam13414
1042417005722	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005723	binding surface
1042417005724	TPR motif; other site
1042417005725	TPR repeat; Region: TPR_11; pfam13414
1042417005726	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1042417005727	binding surface
1042417005728	TPR motif; other site
1042417005729	TPR repeat; Region: TPR_11; pfam13414
1042417005730	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
1042417005731	potential frameshift: common BLAST hit: gi|296126096|ref|YP_003633348.1| MATE efflux family protein
1042417005732	inner membrane protein; Provisional; Region: PRK11715
1042417005733	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH1; cd08185
1042417005734	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1042417005735	putative active site [active]
1042417005736	metal binding site [ion binding]; metal-binding site
1042417005737	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1042417005738	dimerization interface [polypeptide binding]; other site
1042417005739	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417005740	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417005741	dimer interface [polypeptide binding]; other site
1042417005742	putative CheW interface [polypeptide binding]; other site
1042417005743	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1042417005744	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1042417005745	RNA binding surface [nucleotide binding]; other site
1042417005746	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1042417005747	active site
1042417005748	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
1042417005749	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
1042417005750	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1042417005751	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
1042417005752	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1042417005753	ATP binding site [chemical binding]; other site
1042417005754	putative Mg++ binding site [ion binding]; other site
1042417005755	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1042417005756	nucleotide binding region [chemical binding]; other site
1042417005757	ATP-binding site [chemical binding]; other site
1042417005758	TRCF domain; Region: TRCF; pfam03461
1042417005759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1042417005760	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1042417005761	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1042417005762	S-adenosylmethionine binding site [chemical binding]; other site
1042417005763	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
1042417005764	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1042417005765	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1042417005766	Uncharacterized conserved protein [Function unknown]; Region: COG2006
1042417005767	Domain of unknown function (DUF362); Region: DUF362; pfam04015
1042417005768	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1042417005769	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1042417005770	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1042417005771	active site
1042417005772	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1042417005773	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1042417005774	translation initiation factor IF-2; Region: IF-2; TIGR00487
1042417005775	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1042417005776	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1042417005777	G1 box; other site
1042417005778	putative GEF interaction site [polypeptide binding]; other site
1042417005779	GTP/Mg2+ binding site [chemical binding]; other site
1042417005780	Switch I region; other site
1042417005781	G2 box; other site
1042417005782	G3 box; other site
1042417005783	Switch II region; other site
1042417005784	G4 box; other site
1042417005785	G5 box; other site
1042417005786	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1042417005787	Translation-initiation factor 2; Region: IF-2; pfam11987
1042417005788	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1042417005789	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
1042417005790	potential frameshift: common BLAST hit: gi|300870394|ref|YP_003785265.1| putative SAM dependent methyltransferase
1042417005791	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1042417005792	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1042417005793	ligand binding site [chemical binding]; other site
1042417005794	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1042417005795	flagellar motor protein MotP; Reviewed; Region: PRK06926
1042417005796	Flagellar protein (FlbD); Region: FlbD; pfam06289
1042417005797	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1042417005798	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1042417005799	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1042417005800	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1042417005801	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417005802	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1042417005803	putative deacylase active site [active]
1042417005804	EamA-like transporter family; Region: EamA; pfam00892
1042417005805	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1042417005806	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1042417005807	active site
1042417005808	potential frameshift: common BLAST hit: gi|296126950|ref|YP_003634202.1| ATPase AAA
1042417005809	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1042417005810	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
1042417005811	active site
1042417005812	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1042417005813	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1042417005814	putative NAD(P) binding site [chemical binding]; other site
1042417005815	putative substrate binding site [chemical binding]; other site
1042417005816	catalytic Zn binding site [ion binding]; other site
1042417005817	structural Zn binding site [ion binding]; other site
1042417005818	dimer interface [polypeptide binding]; other site
1042417005819	UDP-N-acetylmuramate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: MurB; COG0812
1042417005820	FAD binding domain; Region: FAD_binding_4; pfam01565
1042417005821	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1042417005822	potential frameshift: common BLAST hit: gi|300870377|ref|YP_003785248.1| pyruvate formate-lyase 1-activating enzyme
1042417005823	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1042417005824	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1042417005825	ligand binding site [chemical binding]; other site
1042417005826	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1042417005827	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1042417005828	ligand binding site [chemical binding]; other site
1042417005829	HEAT repeats; Region: HEAT_2; pfam13646
1042417005830	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1042417005831	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1042417005832	LemA family; Region: LemA; cl00742
1042417005833	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
1042417005834	potential frameshift: common BLAST hit: gi|296125743|ref|YP_003632995.1| glycosyl transferase family 2
1042417005835	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
1042417005836	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1042417005837	dimer interface [polypeptide binding]; other site
1042417005838	active site
1042417005839	Rubrerythrin [Energy production and conversion]; Region: COG1592
1042417005840	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1042417005841	binuclear metal center [ion binding]; other site
1042417005842	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1042417005843	iron binding site [ion binding]; other site
1042417005844	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1042417005845	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1042417005846	benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260
1042417005847	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1042417005848	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1042417005849	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1042417005850	catalytic residue [active]
1042417005851	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1042417005852	nucleotide binding site [chemical binding]; other site
1042417005853	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1042417005854	phenylhydantoinase; Validated; Region: PRK08323
1042417005855	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1042417005856	tetramer interface [polypeptide binding]; other site
1042417005857	active site
1042417005858	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417005859	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005860	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005861	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417005862	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005863	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005864	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005865	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005866	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005867	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005868	Ankyrin repeat; Region: Ank; pfam00023
1042417005869	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005870	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005871	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
1042417005872	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1042417005873	selenium-dependent molybdenum hydroxylase 1; Region: Se_dep_Molyb_1; TIGR03311
1042417005874	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1042417005875	catalytic loop [active]
1042417005876	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1042417005877	iron binding site [ion binding]; other site
1042417005878	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1042417005879	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1042417005880	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1042417005881	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1042417005882	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1042417005883	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
1042417005884	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1042417005885	active site
1042417005886	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1042417005887	YheO-like PAS domain; Region: PAS_6; pfam08348
1042417005888	HTH domain; Region: HTH_22; pfam13309
1042417005889	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1042417005890	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1042417005891	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1042417005892	catalytic residue [active]
1042417005893	peptidase; Reviewed; Region: PRK13004
1042417005894	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1042417005895	putative metal binding site [ion binding]; other site
1042417005896	putative dimer interface [polypeptide binding]; other site
1042417005897	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1042417005898	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1042417005899	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1042417005900	carbamate kinase; Reviewed; Region: PRK12686
1042417005901	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1042417005902	putative substrate binding site [chemical binding]; other site
1042417005903	nucleotide binding site [chemical binding]; other site
1042417005904	nucleotide binding site [chemical binding]; other site
1042417005905	homodimer interface [polypeptide binding]; other site
1042417005906	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1042417005907	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1042417005908	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1042417005909	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1042417005910	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1042417005911	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
1042417005912	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; cl08390
1042417005913	xanthine permease; Region: pbuX; TIGR03173
1042417005914	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1042417005915	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1042417005916	Ligand binding site; other site
1042417005917	metal-binding site
1042417005918	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1042417005919	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1042417005920	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
1042417005921	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1042417005922	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1042417005923	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1042417005924	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417005925	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1042417005926	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1042417005927	active site
1042417005928	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1042417005929	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1042417005930	Rubredoxin [Energy production and conversion]; Region: COG1773
1042417005931	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1042417005932	iron binding site [ion binding]; other site
1042417005933	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
1042417005934	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1042417005935	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1042417005936	potential frameshift: common BLAST hit: gi|300870340|ref|YP_003785211.1| 4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein
1042417005937	potential frameshift: common BLAST hit: gi|300870338|ref|YP_003785209.1| acetyl-CoA acetyltransferase
1042417005938	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
1042417005939	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1042417005940	substrate binding site [chemical binding]; other site
1042417005941	oxyanion hole (OAH) forming residues; other site
1042417005942	trimer interface [polypeptide binding]; other site
1042417005943	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1042417005944	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1042417005945	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1042417005946	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1042417005947	heme-binding site [chemical binding]; other site
1042417005948	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1042417005949	MarR family; Region: MarR_2; pfam12802
1042417005950	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1042417005951	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1042417005952	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1042417005953	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005954	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005955	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005956	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005957	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1042417005958	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1042417005959	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1042417005960	binding surface
1042417005961	TPR motif; other site
1042417005962	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1042417005963	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1042417005964	DNA binding residues [nucleotide binding]
1042417005965	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1042417005966	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1042417005967	dimer interface [polypeptide binding]; other site
1042417005968	active site
1042417005969	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1042417005970	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
1042417005971	elongation factor G; Reviewed; Region: PRK12740
1042417005972	G1 box; other site
1042417005973	putative GEF interaction site [polypeptide binding]; other site
1042417005974	GTP/Mg2+ binding site [chemical binding]; other site
1042417005975	Switch I region; other site
1042417005976	G2 box; other site
1042417005977	G3 box; other site
1042417005978	Switch II region; other site
1042417005979	G4 box; other site
1042417005980	G5 box; other site
1042417005981	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1042417005982	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1042417005983	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1042417005984	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1042417005985	active site
1042417005986	phosphorylation site [posttranslational modification]
1042417005987	Putative zinc ribbon domain; Region: DUF164; pfam02591
1042417005988	FlgD Tudor-like domain; Region: FLgD_tudor; cl17881
1042417005989	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
1042417005990	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1042417005991	Zn2+ binding site [ion binding]; other site
1042417005992	Mg2+ binding site [ion binding]; other site
1042417005993	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1042417005994	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1042417005995	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1042417005996	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1042417005997	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1042417005998	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1042417005999	putative substrate translocation pore; other site
1042417006000	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1042417006001	RuvA N terminal domain; Region: RuvA_N; pfam01330
1042417006002	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1042417006003	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1042417006004	metal-binding site [ion binding]
1042417006005	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1042417006006	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
1042417006007	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1042417006008	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1042417006009	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1042417006010	active site
1042417006011	catalytic residues [active]
1042417006012	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; cl01973
1042417006013	N-Utilization Substance G (NusG) N terminal (NGN) insert and Lin0431 are part of DUF1312; Region: DUF1312; cl02206
1042417006014	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1042417006015	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1042417006016	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
1042417006017	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1042417006018	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1042417006019	Coenzyme A binding pocket [chemical binding]; other site
1042417006020	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1042417006021	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1042417006022	putative active site [active]
1042417006023	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1042417006024	cell division protein FtsA; Region: ftsA; TIGR01174
1042417006025	Cell division protein FtsA; Region: FtsA; smart00842
1042417006026	Cell division protein FtsA; Region: FtsA; pfam14450
1042417006027	Flagellar filament outer layer protein Flaa; Region: FlaA; pfam04620
1042417006028	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1042417006029	Isochorismatase family; Region: Isochorismatase; pfam00857
1042417006030	catalytic triad [active]
1042417006031	dimer interface [polypeptide binding]; other site
1042417006032	conserved cis-peptide bond; other site
1042417006033	triosephosphate isomerase; Provisional; Region: PRK14567
1042417006034	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1042417006035	substrate binding site [chemical binding]; other site
1042417006036	dimer interface [polypeptide binding]; other site
1042417006037	catalytic triad [active]
1042417006038	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1042417006039	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1042417006040	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1042417006041	endonuclease III; Region: ENDO3c; smart00478
1042417006042	minor groove reading motif; other site
1042417006043	helix-hairpin-helix signature motif; other site
1042417006044	substrate binding pocket [chemical binding]; other site
1042417006045	active site
1042417006046	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1042417006047	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1042417006048	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1042417006049	nudix motif; other site
1042417006050	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
1042417006051	potential frameshift: common BLAST hit: gi|300870278|ref|YP_003785149.1| molybdate metabolism regulator
1042417006052	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1042417006053	active site
1042417006054	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
1042417006055	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1042417006056	anti sigma factor interaction site; other site
1042417006057	regulatory phosphorylation site [posttranslational modification]; other site
1042417006058	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1042417006059	Trp repressor protein; Region: Trp_repressor; cl17266
1042417006060	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1042417006061	HemN C-terminal domain; Region: HemN_C; pfam06969
1042417006062	RNA polymerase sigma factor RpoS; Region: rpoS_proteo; TIGR02394
1042417006063	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1042417006064	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1042417006065	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1042417006066	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1042417006067	DNA binding residues [nucleotide binding]
1042417006068	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1042417006069	active site
1042417006070	phosphorylation site [posttranslational modification]
1042417006071	intermolecular recognition site; other site
1042417006072	dimerization interface [polypeptide binding]; other site
1042417006073	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1042417006074	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; cl00512
1042417006075	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1042417006076	MarR family; Region: MarR_2; pfam12802
1042417006077	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1042417006078	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1042417006079	acyl-activating enzyme (AAE) consensus motif; other site
1042417006080	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
1042417006081	acyl-activating enzyme (AAE) consensus motif; other site
1042417006082	putative AMP binding site [chemical binding]; other site
1042417006083	putative active site [active]
1042417006084	putative CoA binding site [chemical binding]; other site
1042417006085	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1042417006086	Coenzyme A transferase; Region: CoA_trans; smart00882
1042417006087	Coenzyme A transferase; Region: CoA_trans; cl17247
1042417006088	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1042417006089	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1042417006090	NAD(P) binding site [chemical binding]; other site
1042417006091	homotetramer interface [polypeptide binding]; other site
1042417006092	homodimer interface [polypeptide binding]; other site
1042417006093	active site
1042417006094	putative acyltransferase; Provisional; Region: PRK05790
1042417006095	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1042417006096	dimer interface [polypeptide binding]; other site
1042417006097	active site
1042417006098	potential frameshift: common BLAST hit: gi|300870265|ref|YP_003785136.1| 3-hydroxybutyryl-CoA dehydrogenase
1042417006099	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1042417006100	Na binding site [ion binding]; other site
1042417006101	glycerate kinase; Region: TIGR00045
1042417006102	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1042417006103	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1042417006104	inhibitor-cofactor binding pocket; inhibition site
1042417006105	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1042417006106	catalytic residue [active]
1042417006107	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1042417006108	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1042417006109	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1042417006110	Homeodomain-like domain; Region: HTH_23; pfam13384
1042417006111	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
1042417006112	Helix-turn-helix domain; Region: HTH_36; pfam13730
1042417006113	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417006114	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1042417006115	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1042417006116	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1042417006117	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1042417006118	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1042417006119	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1042417006120	DNA binding residues [nucleotide binding]
1042417006121	putative dimer interface [polypeptide binding]; other site
1042417006122	Uncharacterized conserved protein [Function unknown]; Region: COG4925
1042417006123	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417006124	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417006125	active site
1042417006126	catalytic tetrad [active]
1042417006127	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417006128	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417006129	active site
1042417006130	catalytic tetrad [active]
1042417006131	potential frameshift: common BLAST hit: gi|300870248|ref|YP_003785119.1| putative aldo/keto reductase
1042417006132	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417006133	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417006134	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1042417006135	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1042417006136	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1042417006137	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1042417006138	dimerization interface [polypeptide binding]; other site
1042417006139	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1042417006140	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417006141	Uncharacterized conserved protein [Function unknown]; Region: COG4925
1042417006142	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1042417006143	trimer interface [polypeptide binding]; other site
1042417006144	active site
1042417006145	substrate binding site [chemical binding]; other site
1042417006146	CoA binding site [chemical binding]; other site
1042417006147	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1042417006148	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1042417006149	active site
1042417006150	catalytic tetrad [active]
1042417006151	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1042417006152	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1042417006153	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417006154	short chain dehydrogenase; Provisional; Region: PRK06940
1042417006155	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1042417006156	NAD(P) binding site [chemical binding]; other site
1042417006157	active site
1042417006158	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1042417006159	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
1042417006160	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1042417006161	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1042417006162	substrate binding site [chemical binding]; other site
1042417006163	ATP binding site [chemical binding]; other site
1042417006164	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1042417006165	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1042417006166	active site
1042417006167	Cache domain; Region: Cache_1; pfam02743
1042417006168	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1042417006169	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1042417006170	dimer interface [polypeptide binding]; other site
1042417006171	putative CheW interface [polypeptide binding]; other site
1042417006172	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1042417006173	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1042417006174	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1042417006175	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1042417006176	peptide binding site [polypeptide binding]; other site
1042417006177	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1042417006178	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1042417006179	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417006180	dimer interface [polypeptide binding]; other site
1042417006181	conserved gate region; other site
1042417006182	putative PBP binding loops; other site
1042417006183	ABC-ATPase subunit interface; other site
1042417006184	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1042417006185	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1042417006186	dimer interface [polypeptide binding]; other site
1042417006187	conserved gate region; other site
1042417006188	putative PBP binding loops; other site
1042417006189	ABC-ATPase subunit interface; other site