-- dump date 20140619_010925 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002731780.1 225851547 7676729 634..2274 1 NC_012441.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 2274 dnaA 7676729 dnaA Brucella melitensis ATCC 23457 chromosomal replication initiation protein YP_002731780.1 634 D 546272 CDS YP_002731781.1 225851548 7678227 2503..3696 1 NC_012441.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3696 dnaN 7678227 dnaN Brucella melitensis ATCC 23457 DNA polymerase III subunit beta YP_002731781.1 2503 D 546272 CDS YP_002731782.1 225851549 7678228 3878..5032 1 NC_012441.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5032 recF 7678228 recF Brucella melitensis ATCC 23457 recombination protein F YP_002731782.1 3878 D 546272 CDS YP_002731783.1 225851550 7678229 5070..5852 1 NC_012441.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 5852 7678229 BMEA_A0004 Brucella melitensis ATCC 23457 molybdopterin biosynthesis protein MoeB YP_002731783.1 5070 D 546272 CDS YP_002731784.1 225851551 7678230 complement(5869..6825) 1 NC_012441.1 D-isomer specific 2-hydroxyacid dehydrogenase 6825 7678230 BMEA_A0005 Brucella melitensis ATCC 23457 D-isomer specific 2-hydroxyacid dehydrogenase YP_002731784.1 5869 R 546272 CDS YP_002731785.1 225851552 7678231 complement(6822..8447) 1 NC_012441.1 ABC transporter 8447 7678231 BMEA_A0006 Brucella melitensis ATCC 23457 ABC transporter YP_002731785.1 6822 R 546272 CDS YP_002731786.1 225851553 7678232 complement(8471..9610) 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 9610 7678232 BMEA_A0007 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002731786.1 8471 R 546272 CDS YP_002731787.1 225851554 7678233 complement(9610..10707) 1 NC_012441.1 hypothetical protein 10707 7678233 BMEA_A0008 Brucella melitensis ATCC 23457 hypothetical protein YP_002731787.1 9610 R 546272 CDS YP_002731788.1 225851555 7678234 complement(10819..12657) 1 NC_012441.1 family 5 extracellular solute-binding protein 12657 7678234 BMEA_A0009 Brucella melitensis ATCC 23457 family 5 extracellular solute-binding protein YP_002731788.1 10819 R 546272 CDS YP_002731789.1 225851556 7678235 complement(12671..14539) 1 NC_012441.1 family 5 extracellular solute-binding protein 14539 7678235 BMEA_A0010 Brucella melitensis ATCC 23457 family 5 extracellular solute-binding protein YP_002731789.1 12671 R 546272 CDS YP_002731790.1 225851557 7678236 complement(14770..15093) 1 NC_012441.1 hypothetical protein 15093 7678236 BMEA_A0011 Brucella melitensis ATCC 23457 hypothetical protein YP_002731790.1 14770 R 546272 CDS YP_002731791.1 225851558 7678237 complement(15139..15339) 1 NC_012441.1 hypothetical protein 15339 7678237 BMEA_A0012 Brucella melitensis ATCC 23457 hypothetical protein YP_002731791.1 15139 R 546272 CDS YP_002731792.1 225851559 7678238 complement(15379..15537) 1 NC_012441.1 hypothetical protein 15537 7678238 BMEA_A0013 Brucella melitensis ATCC 23457 hypothetical protein YP_002731792.1 15379 R 546272 CDS YP_002731793.1 225851560 7678239 complement(15994..17100) 1 NC_012441.1 extracellular ligand-binding receptor 17100 7678239 BMEA_A0014 Brucella melitensis ATCC 23457 extracellular ligand-binding receptor YP_002731793.1 15994 R 546272 CDS YP_002731794.1 225851561 7678241 17372..17572 1 NC_012441.1 hypothetical protein 17572 7678241 BMEA_A0016 Brucella melitensis ATCC 23457 hypothetical protein YP_002731794.1 17372 D 546272 CDS YP_002731795.1 225851562 7678242 complement(18358..19221) 1 NC_012441.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; hydroxymethylglutaryl-CoA lyase 19221 7678242 BMEA_A0017 Brucella melitensis ATCC 23457 hydroxymethylglutaryl-CoA lyase YP_002731795.1 18358 R 546272 CDS YP_002731796.1 225851563 7678243 complement(19214..21181) 1 NC_012441.1 carbamoyl-phosphate synthase subunit L 21181 7678243 BMEA_A0018 Brucella melitensis ATCC 23457 carbamoyl-phosphate synthase subunit L YP_002731796.1 19214 R 546272 CDS YP_002731797.1 225851564 7678244 complement(21247..22854) 1 NC_012441.1 propionyl-CoA carboxylase 22854 7678244 BMEA_A0019 Brucella melitensis ATCC 23457 propionyl-CoA carboxylase YP_002731797.1 21247 R 546272 CDS YP_002731798.1 225851565 7678245 complement(22854..24032) 1 NC_012441.1 isovaleryl-CoA dehydrogenase 24032 7678245 BMEA_A0020 Brucella melitensis ATCC 23457 isovaleryl-CoA dehydrogenase YP_002731798.1 22854 R 546272 CDS YP_002731799.1 225851566 7678247 complement(26352..26786) 1 NC_012441.1 CHRD domain-containing protein 26786 7678247 BMEA_A0022 Brucella melitensis ATCC 23457 CHRD domain-containing protein YP_002731799.1 26352 R 546272 CDS YP_002731800.1 225851567 7678248 complement(26963..28084) 1 NC_012441.1 acyltransferase MdmB 28084 7678248 BMEA_A0023 Brucella melitensis ATCC 23457 acyltransferase MdmB YP_002731800.1 26963 R 546272 CDS YP_002731801.1 225851568 7678250 complement(28607..28990) 1 NC_012441.1 hypothetical protein 28990 7678250 BMEA_A0025 Brucella melitensis ATCC 23457 hypothetical protein YP_002731801.1 28607 R 546272 CDS YP_002731802.1 225851569 7678251 29375..30727 1 NC_012441.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 30727 aroA 7678251 aroA Brucella melitensis ATCC 23457 3-phosphoshikimate 1-carboxyvinyltransferase YP_002731802.1 29375 D 546272 CDS YP_002731803.1 225851570 7678252 30724..31383 1 NC_012441.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 31383 cmk 7678252 cmk Brucella melitensis ATCC 23457 cytidylate kinase YP_002731803.1 30724 D 546272 CDS YP_002731804.1 225851571 7678253 31599..33299 1 NC_012441.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 33299 rpsA 7678253 rpsA Brucella melitensis ATCC 23457 30S ribosomal protein S1 YP_002731804.1 31599 D 546272 CDS YP_002731805.1 225851572 7678254 complement(33717..34727) 1 NC_012441.1 hypothetical protein 34727 7678254 BMEA_A0029 Brucella melitensis ATCC 23457 hypothetical protein YP_002731805.1 33717 R 546272 CDS YP_002731806.1 225851573 7678255 34843..35742 1 NC_012441.1 LysR family transcriptional regulator 35742 7678255 BMEA_A0030 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002731806.1 34843 D 546272 CDS YP_002731807.1 225851574 7678256 complement(36348..37631) 1 NC_012441.1 lytic murein transglycosylase 37631 7678256 BMEA_A0031 Brucella melitensis ATCC 23457 lytic murein transglycosylase YP_002731807.1 36348 R 546272 CDS YP_002731808.1 225851575 7678257 complement(37647..38252) 1 NC_012441.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 38252 recR 7678257 recR Brucella melitensis ATCC 23457 recombination protein RecR YP_002731808.1 37647 R 546272 CDS YP_002731809.1 225851576 7678258 complement(38383..38706) 1 NC_012441.1 hypothetical protein 38706 7678258 BMEA_A0033 Brucella melitensis ATCC 23457 hypothetical protein YP_002731809.1 38383 R 546272 CDS YP_002731810.1 225851577 7678259 complement(38731..40539) 1 NC_012441.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 40539 dnaX 7678259 dnaX Brucella melitensis ATCC 23457 DNA polymerase III subunits gamma and tau YP_002731810.1 38731 R 546272 CDS YP_002731811.1 225851578 7678261 40821..41225 1 NC_012441.1 histidine triad protein 41225 7678261 BMEA_A0037 Brucella melitensis ATCC 23457 histidine triad protein YP_002731811.1 40821 D 546272 CDS YP_002731812.1 225851579 7678262 41254..42201 1 NC_012441.1 peroxisomal NADH pyrophosphatase NUDT12 42201 7678262 BMEA_A0038 Brucella melitensis ATCC 23457 peroxisomal NADH pyrophosphatase NUDT12 YP_002731812.1 41254 D 546272 CDS YP_002731813.1 225851580 7678263 complement(42202..43065) 1 NC_012441.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 43065 7678263 BMEA_A0039 Brucella melitensis ATCC 23457 prephenate dehydratase YP_002731813.1 42202 R 546272 CDS YP_002731814.1 225851581 7678264 complement(43154..43909) 1 NC_012441.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 43909 kdsB 7678264 kdsB Brucella melitensis ATCC 23457 3-deoxy-manno-octulosonate cytidylyltransferase YP_002731814.1 43154 R 546272 CDS YP_002731815.1 225851582 7678265 44287..44895 1 NC_012441.1 cytochrome c 44895 7678265 BMEA_A0041 Brucella melitensis ATCC 23457 cytochrome c YP_002731815.1 44287 D 546272 CDS YP_002731816.1 225851583 7678266 complement(44940..45905) 1 NC_012441.1 hypothetical protein 45905 7678266 BMEA_A0042 Brucella melitensis ATCC 23457 hypothetical protein YP_002731816.1 44940 R 546272 CDS YP_002731817.1 225851584 7678267 45961..46269 1 NC_012441.1 hypothetical protein 46269 7678267 BMEA_A0043 Brucella melitensis ATCC 23457 hypothetical protein YP_002731817.1 45961 D 546272 CDS YP_002731818.1 225851585 7678268 46444..47472 1 NC_012441.1 ubiquinol oxidase subunit II 47472 cyoA 7678268 cyoA Brucella melitensis ATCC 23457 ubiquinol oxidase subunit II YP_002731818.1 46444 D 546272 CDS YP_002731819.1 225851586 7678269 47536..49515 1 NC_012441.1 cytochrome o ubiquinol oxidase subunit I 49515 cyoB 7678269 cyoB Brucella melitensis ATCC 23457 cytochrome o ubiquinol oxidase subunit I YP_002731819.1 47536 D 546272 CDS YP_002731820.1 225851587 7678270 49519..50148 1 NC_012441.1 cytochrome o ubiquinol oxidase subunit III 50148 cyoC 7678270 cyoC Brucella melitensis ATCC 23457 cytochrome o ubiquinol oxidase subunit III YP_002731820.1 49519 D 546272 CDS YP_002731821.1 225851588 7678271 50148..50513 1 NC_012441.1 cytochrome o ubiquinol oxidase subunit IV 50513 cyoD 7678271 cyoD Brucella melitensis ATCC 23457 cytochrome o ubiquinol oxidase subunit IV YP_002731821.1 50148 D 546272 CDS YP_002731822.1 225851589 7678272 51067..51663 1 NC_012441.1 SH3 type 3 domain-containing protein 51663 7678272 BMEA_A0048 Brucella melitensis ATCC 23457 SH3 type 3 domain-containing protein YP_002731822.1 51067 D 546272 CDS YP_002731823.1 225851590 7678273 52148..54067 1 NC_012441.1 surface antigen D15 54067 7678273 BMEA_A0049 Brucella melitensis ATCC 23457 surface antigen D15 YP_002731823.1 52148 D 546272 CDS YP_002731824.1 225851591 7678274 54064..58803 1 NC_012441.1 hypothetical protein 58803 7678274 BMEA_A0050 Brucella melitensis ATCC 23457 hypothetical protein YP_002731824.1 54064 D 546272 CDS YP_002731825.1 225851592 7678276 complement(59725..59940) 1 NC_012441.1 hypothetical protein 59940 7678276 BMEA_A0052 Brucella melitensis ATCC 23457 hypothetical protein YP_002731825.1 59725 R 546272 CDS YP_002731826.1 225851593 7678277 complement(60010..60519) 1 NC_012441.1 hypothetical protein 60519 7678277 BMEA_A0053 Brucella melitensis ATCC 23457 hypothetical protein YP_002731826.1 60010 R 546272 CDS YP_002731827.1 225851594 7678278 complement(60850..61056) 1 NC_012441.1 hypothetical protein 61056 7678278 BMEA_A0054 Brucella melitensis ATCC 23457 hypothetical protein YP_002731827.1 60850 R 546272 CDS YP_002731828.1 225851595 7678279 complement(61067..62071) 1 NC_012441.1 hypothetical protein 62071 7678279 BMEA_A0055 Brucella melitensis ATCC 23457 hypothetical protein YP_002731828.1 61067 R 546272 CDS YP_002731829.1 225851596 7678280 complement(62206..62604) 1 NC_012441.1 hypothetical protein 62604 7678280 BMEA_A0056 Brucella melitensis ATCC 23457 hypothetical protein YP_002731829.1 62206 R 546272 CDS YP_002731830.1 225851597 7678281 complement(62849..63244) 1 NC_012441.1 glyoxalase/bleomycin resistance protein/dioxygenase 63244 7678281 BMEA_A0057 Brucella melitensis ATCC 23457 glyoxalase/bleomycin resistance protein/dioxygenase YP_002731830.1 62849 R 546272 CDS YP_002731831.1 225851598 7678282 63441..64604 1 NC_012441.1 hypothetical protein 64604 7678282 BMEA_A0058 Brucella melitensis ATCC 23457 hypothetical protein YP_002731831.1 63441 D 546272 CDS YP_002731832.1 225851599 7678283 complement(64817..66448) 1 NC_012441.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 66448 7678283 BMEA_A0059 Brucella melitensis ATCC 23457 phosphoglucomutase YP_002731832.1 64817 R 546272 CDS YP_002731833.1 225851600 7678284 complement(66504..66689) 1 NC_012441.1 hypothetical protein 66689 7678284 BMEA_A0061 Brucella melitensis ATCC 23457 hypothetical protein YP_002731833.1 66504 R 546272 CDS YP_002731834.1 225851601 7678285 complement(66664..67557) 1 NC_012441.1 LysR family transcriptional regulator 67557 7678285 BMEA_A0062 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002731834.1 66664 R 546272 CDS YP_002731835.1 225851602 7678286 complement(67597..67701) 1 NC_012441.1 hypothetical protein 67701 7678286 BMEA_A0063 Brucella melitensis ATCC 23457 hypothetical protein YP_002731835.1 67597 R 546272 CDS YP_002731836.1 225851603 7678287 67682..68605 1 NC_012441.1 dienelactone hydrolase domain-containing protein 68605 7678287 BMEA_A0064 Brucella melitensis ATCC 23457 dienelactone hydrolase domain-containing protein YP_002731836.1 67682 D 546272 CDS YP_002731837.1 225851604 7678288 68678..69376 1 NC_012441.1 putative fructose transport system kinase 69376 7678288 BMEA_A0065 Brucella melitensis ATCC 23457 putative fructose transport system kinase YP_002731837.1 68678 D 546272 CDS YP_002731838.1 225851605 7678289 69476..70165 1 NC_012441.1 fumarylacetoacetate hydrolase domain-containing protein 1 70165 7678289 BMEA_A0066 Brucella melitensis ATCC 23457 fumarylacetoacetate hydrolase domain-containing protein 1 YP_002731838.1 69476 D 546272 CDS YP_002731839.1 225851606 7678290 70185..70376 1 NC_012441.1 hypothetical protein 70376 7678290 BMEA_A0067 Brucella melitensis ATCC 23457 hypothetical protein YP_002731839.1 70185 D 546272 CDS YP_002731840.1 225851607 7678291 70438..70653 1 NC_012441.1 hypothetical protein 70653 7678291 BMEA_A0068 Brucella melitensis ATCC 23457 hypothetical protein YP_002731840.1 70438 D 546272 CDS YP_002731841.1 225851608 7678292 70819..71007 1 NC_012441.1 hypothetical protein 71007 7678292 BMEA_A0069 Brucella melitensis ATCC 23457 hypothetical protein YP_002731841.1 70819 D 546272 CDS YP_002731842.1 225851609 7678293 71022..71885 1 NC_012441.1 lytic transglycosylase 71885 7678293 BMEA_A0070 Brucella melitensis ATCC 23457 lytic transglycosylase YP_002731842.1 71022 D 546272 CDS YP_002731843.1 225851610 7678294 72067..72723 1 NC_012441.1 hemolysin-3 72723 7678294 BMEA_A0071 Brucella melitensis ATCC 23457 hemolysin-3 YP_002731843.1 72067 D 546272 CDS YP_002731844.1 225851611 7678295 complement(72864..76097) 1 NC_012441.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 76097 dnaE 7678295 dnaE Brucella melitensis ATCC 23457 error-prone DNA polymerase YP_002731844.1 72864 R 546272 CDS YP_002731845.1 225851612 7678296 complement(76097..77683) 1 NC_012441.1 hypothetical protein 77683 7678296 BMEA_A0073 Brucella melitensis ATCC 23457 hypothetical protein YP_002731845.1 76097 R 546272 CDS YP_002731846.1 225851613 7678297 complement(77574..78437) 1 NC_012441.1 hypothetical protein 78437 7678297 BMEA_A0074 Brucella melitensis ATCC 23457 hypothetical protein YP_002731846.1 77574 R 546272 CDS YP_002731847.1 225851614 7678299 81199..81936 1 NC_012441.1 hypothetical protein 81936 7678299 BMEA_A0076 Brucella melitensis ATCC 23457 hypothetical protein YP_002731847.1 81199 D 546272 CDS YP_002731848.1 225851615 7678300 complement(82015..83235) 1 NC_012441.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 83235 argG 7678300 argG Brucella melitensis ATCC 23457 argininosuccinate synthase YP_002731848.1 82015 R 546272 CDS YP_002731849.1 225851616 7678301 83422..84081 1 NC_012441.1 hypothetical protein 84081 7678301 BMEA_A0078 Brucella melitensis ATCC 23457 hypothetical protein YP_002731849.1 83422 D 546272 CDS YP_002731850.1 225851617 7678302 complement(84085..84588) 1 NC_012441.1 hypothetical protein 84588 7678302 BMEA_A0079 Brucella melitensis ATCC 23457 hypothetical protein YP_002731850.1 84085 R 546272 CDS YP_002731851.1 225851618 7678303 complement(84622..85857) 1 NC_012441.1 radical SAM protein 85857 7678303 BMEA_A0080 Brucella melitensis ATCC 23457 radical SAM protein YP_002731851.1 84622 R 546272 CDS YP_002731852.1 225851619 7678304 complement(86117..86620) 1 NC_012441.1 hypothetical protein 86620 7678304 BMEA_A0083 Brucella melitensis ATCC 23457 hypothetical protein YP_002731852.1 86117 R 546272 CDS YP_002731853.1 225851620 7678305 complement(87036..87419) 1 NC_012441.1 hypothetical protein 87419 7678305 BMEA_A0084 Brucella melitensis ATCC 23457 hypothetical protein YP_002731853.1 87036 R 546272 CDS YP_002731854.1 225851621 7678306 complement(87507..87800) 1 NC_012441.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 87800 7678306 BMEA_A0085 Brucella melitensis ATCC 23457 pterin-4-alpha-carbinolamine dehydratase YP_002731854.1 87507 R 546272 CDS YP_002731855.1 225851622 7678307 complement(88542..89132) 1 NC_012441.1 2'-5' RNA ligase 89132 7678307 BMEA_A0087 Brucella melitensis ATCC 23457 2'-5' RNA ligase YP_002731855.1 88542 R 546272 CDS YP_002731856.1 225851623 7676515 complement(89313..90038) 1 NC_012441.1 arylesterase precursor 90038 7676515 BMEA_A0088 Brucella melitensis ATCC 23457 arylesterase precursor YP_002731856.1 89313 R 546272 CDS YP_002731857.1 225851624 7676516 complement(90035..90613) 1 NC_012441.1 hypothetical protein 90613 7676516 BMEA_A0089 Brucella melitensis ATCC 23457 hypothetical protein YP_002731857.1 90035 R 546272 CDS YP_002731858.1 225851625 7676517 90784..90912 1 NC_012441.1 ABC transporter 90912 7676517 BMEA_A0090 Brucella melitensis ATCC 23457 ABC transporter YP_002731858.1 90784 D 546272 CDS YP_002731859.1 225851626 7676518 90909..93458 1 NC_012441.1 hypothetical protein 93458 7676518 BMEA_A0091 Brucella melitensis ATCC 23457 hypothetical protein YP_002731859.1 90909 D 546272 CDS YP_002731860.1 225851627 7676519 93692..94429 1 NC_012441.1 hypothetical protein 94429 7676519 BMEA_A0093 Brucella melitensis ATCC 23457 hypothetical protein YP_002731860.1 93692 D 546272 CDS YP_002731861.1 225851628 7676520 94544..95083 1 NC_012441.1 phosphinothricin N-acetyltransferase 95083 7676520 BMEA_A0094 Brucella melitensis ATCC 23457 phosphinothricin N-acetyltransferase YP_002731861.1 94544 D 546272 CDS YP_002731862.1 225851629 7676521 complement(95103..95504) 1 NC_012441.1 hypothetical protein 95504 7676521 BMEA_A0095 Brucella melitensis ATCC 23457 hypothetical protein YP_002731862.1 95103 R 546272 CDS YP_002731863.1 225851630 7676522 complement(96054..96788) 1 NC_012441.1 hypothetical protein 96788 7676522 BMEA_A0096 Brucella melitensis ATCC 23457 hypothetical protein YP_002731863.1 96054 R 546272 CDS YP_002731864.1 225851631 7676523 complement(96941..97081) 1 NC_012441.1 hypothetical protein 97081 7676523 BMEA_A0097 Brucella melitensis ATCC 23457 hypothetical protein YP_002731864.1 96941 R 546272 CDS YP_002731865.1 225851632 7676524 complement(97065..99752) 1 NC_012441.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 99752 acnA 7676524 acnA Brucella melitensis ATCC 23457 aconitate hydratase YP_002731865.1 97065 R 546272 CDS YP_002731866.1 225851633 7676525 100096..100743 1 NC_012441.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 100743 ccmA 7676525 ccmA Brucella melitensis ATCC 23457 cytochrome c biogenesis protein CcmA YP_002731866.1 100096 D 546272 CDS YP_002731867.1 225851634 7676526 100743..101408 1 NC_012441.1 heme exporter protein CcmB 101408 ccmB 7676526 ccmB Brucella melitensis ATCC 23457 heme exporter protein CcmB YP_002731867.1 100743 D 546272 CDS YP_002731868.1 225851635 7676527 101466..102251 1 NC_012441.1 heme exporter protein CcmC 102251 ccmC 7676527 ccmC Brucella melitensis ATCC 23457 heme exporter protein CcmC YP_002731868.1 101466 D 546272 CDS YP_002731869.1 225851636 7676528 102248..102421 1 NC_012441.1 heme exporter protein CcmD 102421 ccmD 7676528 ccmD Brucella melitensis ATCC 23457 heme exporter protein CcmD YP_002731869.1 102248 D 546272 CDS YP_002731870.1 225851637 7676529 102418..103029 1 NC_012441.1 periplasmic protein thiol:disulfide oxidoreductase 103029 dsbE 7676529 dsbE Brucella melitensis ATCC 23457 periplasmic protein thiol:disulfide oxidoreductase YP_002731870.1 102418 D 546272 CDS YP_002731871.1 225851638 7676530 complement(103278..105113) 1 NC_012441.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 105113 ilvD 7676530 ilvD Brucella melitensis ATCC 23457 dihydroxy-acid dehydratase YP_002731871.1 103278 R 546272 CDS YP_002731872.1 225851639 7676531 105286..105423 1 NC_012441.1 hypothetical protein 105423 7676531 BMEA_A0106 Brucella melitensis ATCC 23457 hypothetical protein YP_002731872.1 105286 D 546272 CDS YP_002731873.1 225851640 7676532 complement(105504..105935) 1 NC_012441.1 hypothetical protein 105935 7676532 BMEA_A0107 Brucella melitensis ATCC 23457 hypothetical protein YP_002731873.1 105504 R 546272 CDS YP_002731874.1 225851641 7676533 complement(105962..106339) 1 NC_012441.1 response regulator receiver protein 106339 7676533 BMEA_A0108 Brucella melitensis ATCC 23457 response regulator receiver protein YP_002731874.1 105962 R 546272 CDS YP_002731875.1 225851642 7676534 complement(106514..106750) 1 NC_012441.1 AsnC family transcriptional regulator 106750 7676534 BMEA_A0109 Brucella melitensis ATCC 23457 AsnC family transcriptional regulator YP_002731875.1 106514 R 546272 CDS YP_002731876.1 225851643 7676535 107069..107257 1 NC_012441.1 hypothetical protein 107257 7676535 BMEA_A0110 Brucella melitensis ATCC 23457 hypothetical protein YP_002731876.1 107069 D 546272 CDS YP_002731877.1 225851644 7676536 107403..107807 1 NC_012441.1 hypothetical protein 107807 7676536 BMEA_A0111 Brucella melitensis ATCC 23457 hypothetical protein YP_002731877.1 107403 D 546272 CDS YP_002731878.1 225851645 7676537 complement(107893..108597) 1 NC_012441.1 hypothetical protein 108597 7676537 BMEA_A0112 Brucella melitensis ATCC 23457 hypothetical protein YP_002731878.1 107893 R 546272 CDS YP_002731879.1 225851646 7676538 108669..109487 1 NC_012441.1 hypothetical protein 109487 7676538 BMEA_A0113 Brucella melitensis ATCC 23457 hypothetical protein YP_002731879.1 108669 D 546272 CDS YP_002731880.1 225851647 7676539 109765..110793 1 NC_012441.1 sulfate ABC transporter substrate-binding protein 110793 7676539 BMEA_A0114 Brucella melitensis ATCC 23457 sulfate ABC transporter substrate-binding protein YP_002731880.1 109765 D 546272 CDS YP_002731881.1 225851648 7676540 110888..111754 1 NC_012441.1 sulfate ABC transporter permease CysT 111754 cysT 7676540 cysT Brucella melitensis ATCC 23457 sulfate ABC transporter permease CysT YP_002731881.1 110888 D 546272 CDS YP_002731882.1 225851649 7676541 111744..112610 1 NC_012441.1 sulfate ABC transporter permease CysW 112610 cysW 7676541 cysW Brucella melitensis ATCC 23457 sulfate ABC transporter permease CysW YP_002731882.1 111744 D 546272 CDS YP_002731883.1 225851650 7676542 112708..113787 1 NC_012441.1 sulfate ABC transporter ATP-binding protein 113787 cysA 7676542 cysA Brucella melitensis ATCC 23457 sulfate ABC transporter ATP-binding protein YP_002731883.1 112708 D 546272 CDS YP_002731884.1 225851651 7676543 114173..122776 1 NC_012441.1 glycosyltransferase 122776 7676543 BMEA_A0118 Brucella melitensis ATCC 23457 glycosyltransferase YP_002731884.1 114173 D 546272 CDS YP_002731885.1 225851652 7676544 122866..124170 1 NC_012441.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 124170 pncB 7676544 pncB Brucella melitensis ATCC 23457 nicotinate phosphoribosyltransferase YP_002731885.1 122866 D 546272 CDS YP_002731886.1 225851653 7676545 complement(124212..125042) 1 NC_012441.1 phenazine biosynthesis protein PhzF family protein 125042 7676545 BMEA_A0120 Brucella melitensis ATCC 23457 phenazine biosynthesis protein PhzF family protein YP_002731886.1 124212 R 546272 CDS YP_002731887.1 225851654 7676546 complement(125152..125940) 1 NC_012441.1 methyltransferase type 11 125940 7676546 BMEA_A0121 Brucella melitensis ATCC 23457 methyltransferase type 11 YP_002731887.1 125152 R 546272 CDS YP_002731888.1 225851655 7676547 complement(125963..126898) 1 NC_012441.1 fructokinase 126898 7676547 BMEA_A0122 Brucella melitensis ATCC 23457 fructokinase YP_002731888.1 125963 R 546272 CDS YP_002731889.1 225851656 7676548 complement(126989..127795) 1 NC_012441.1 short-chain dehydrogenase/reductase SDR 127795 7676548 BMEA_A0123 Brucella melitensis ATCC 23457 short-chain dehydrogenase/reductase SDR YP_002731889.1 126989 R 546272 CDS YP_002731890.1 225851657 7676549 complement(127916..130207) 1 NC_012441.1 1A family penicillin-binding protein 130207 7676549 BMEA_A0124 Brucella melitensis ATCC 23457 1A family penicillin-binding protein YP_002731890.1 127916 R 546272 CDS YP_002731891.1 225851658 7676550 complement(130413..131105) 1 NC_012441.1 porin 131105 7676550 BMEA_A0125 Brucella melitensis ATCC 23457 porin YP_002731891.1 130413 R 546272 CDS YP_002731892.1 225851659 7676551 complement(131372..132058) 1 NC_012441.1 outer membrane protein 132058 7676551 BMEA_A0126 Brucella melitensis ATCC 23457 outer membrane protein YP_002731892.1 131372 R 546272 CDS YP_002731893.1 225851660 7676552 complement(132290..132907) 1 NC_012441.1 hypothetical protein 132907 7676552 BMEA_A0127 Brucella melitensis ATCC 23457 hypothetical protein YP_002731893.1 132290 R 546272 CDS YP_002731894.1 225851661 7676553 complement(132946..134361) 1 NC_012441.1 hypothetical protein 134361 7676553 BMEA_A0128 Brucella melitensis ATCC 23457 hypothetical protein YP_002731894.1 132946 R 546272 CDS YP_002731895.1 225851662 7676554 134592..134840 1 NC_012441.1 hypothetical protein 134840 7676554 BMEA_A0129 Brucella melitensis ATCC 23457 hypothetical protein YP_002731895.1 134592 D 546272 CDS YP_002731896.1 225851663 7676555 134922..137858 1 NC_012441.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 137858 polA 7676555 polA Brucella melitensis ATCC 23457 DNA polymerase I YP_002731896.1 134922 D 546272 CDS YP_002731897.1 225851664 7676556 138000..139880 1 NC_012441.1 DEAD/DEAH box helicase 139880 7676556 BMEA_A0131 Brucella melitensis ATCC 23457 DEAD/DEAH box helicase YP_002731897.1 138000 D 546272 CDS YP_002731898.1 225851665 7676557 complement(139976..142417) 1 NC_012441.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 142417 gyrB 7676557 gyrB Brucella melitensis ATCC 23457 DNA gyrase subunit B YP_002731898.1 139976 R 546272 CDS YP_002731899.1 225851666 7676558 complement(142468..142635) 1 NC_012441.1 hypothetical protein 142635 7676558 BMEA_A0133 Brucella melitensis ATCC 23457 hypothetical protein YP_002731899.1 142468 R 546272 CDS YP_002731900.1 225851667 7676562 complement(144707..145819) 1 NC_012441.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 145819 7676562 BMEA_A0137 Brucella melitensis ATCC 23457 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase YP_002731900.1 144707 R 546272 CDS YP_002731901.1 225851668 7676563 complement(145853..146209) 1 NC_012441.1 hypothetical protein 146209 7676563 BMEA_A0138 Brucella melitensis ATCC 23457 hypothetical protein YP_002731901.1 145853 R 546272 CDS YP_002731902.1 225851669 7676565 148776..150068 1 NC_012441.1 sensor histidine kinase regB 150068 7676565 BMEA_A0140 Brucella melitensis ATCC 23457 sensor histidine kinase regB YP_002731902.1 148776 D 546272 CDS YP_002731903.1 225851670 7676566 150138..150506 1 NC_012441.1 transposase 150506 7676566 BMEA_A0141 Brucella melitensis ATCC 23457 transposase YP_002731903.1 150138 D 546272 CDS YP_002731904.1 225851671 7676567 150503..150781 1 NC_012441.1 IS6501 transposase 150781 7676567 BMEA_A0142 Brucella melitensis ATCC 23457 IS6501 transposase YP_002731904.1 150503 D 546272 CDS YP_002731905.1 225851672 7676568 151496..152059 1 NC_012441.1 photosynthetic apparatus regulatory protein regA 152059 7676568 BMEA_A0143 Brucella melitensis ATCC 23457 photosynthetic apparatus regulatory protein regA YP_002731905.1 151496 D 546272 CDS YP_002731906.1 225851673 7676569 complement(152065..152367) 1 NC_012441.1 hypothetical protein 152367 7676569 BMEA_A0144 Brucella melitensis ATCC 23457 hypothetical protein YP_002731906.1 152065 R 546272 CDS YP_002731907.1 225851674 7676570 152829..153449 1 NC_012441.1 ErfK/YbiS/YcfS/YnhG family protein 153449 7676570 BMEA_A0145 Brucella melitensis ATCC 23457 ErfK/YbiS/YcfS/YnhG family protein YP_002731907.1 152829 D 546272 CDS YP_002731908.1 225851675 7676571 complement(153539..154111) 1 NC_012441.1 NifU-like protein 154111 7676571 BMEA_A0146 Brucella melitensis ATCC 23457 NifU-like protein YP_002731908.1 153539 R 546272 CDS YP_002731909.1 225851676 7676572 complement(154220..154759) 1 NC_012441.1 UspA domain-containing protein 154759 7676572 BMEA_A0147 Brucella melitensis ATCC 23457 UspA domain-containing protein YP_002731909.1 154220 R 546272 CDS YP_002731910.1 225851677 7676573 complement(154766..155923) 1 NC_012441.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 155923 trpS 7676573 trpS Brucella melitensis ATCC 23457 tryptophanyl-tRNA synthetase YP_002731910.1 154766 R 546272 CDS YP_002731911.1 225851678 7676574 complement(155930..157519) 1 NC_012441.1 integral membrane protein MviN 157519 mviN 7676574 mviN Brucella melitensis ATCC 23457 integral membrane protein MviN YP_002731911.1 155930 R 546272 CDS YP_002731912.1 225851679 7676575 complement(157533..160337) 1 NC_012441.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 160337 glnD 7676575 glnD Brucella melitensis ATCC 23457 PII uridylyl-transferase YP_002731912.1 157533 R 546272 CDS YP_002731913.1 225851680 7676576 160403..160498 1 NC_012441.1 hypothetical protein 160498 7676576 BMEA_A0151 Brucella melitensis ATCC 23457 hypothetical protein YP_002731913.1 160403 D 546272 CDS YP_002731914.1 225851681 7676578 162930..165662 1 NC_012441.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 165662 mutS 7676578 mutS Brucella melitensis ATCC 23457 DNA mismatch repair protein MutS YP_002731914.1 162930 D 546272 CDS YP_002731915.1 225851682 7676579 complement(165968..166861) 1 NC_012441.1 hypothetical protein 166861 7676579 BMEA_A0154 Brucella melitensis ATCC 23457 hypothetical protein YP_002731915.1 165968 R 546272 CDS YP_002731916.1 225851683 7676580 complement(167136..167618) 1 NC_012441.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 167618 lspA 7676580 lspA Brucella melitensis ATCC 23457 lipoprotein signal peptidase YP_002731916.1 167136 R 546272 CDS YP_002731917.1 225851684 7676581 complement(167620..168513) 1 NC_012441.1 tRNA/rRNA methyltransferase SpoU 168513 7676581 BMEA_A0156 Brucella melitensis ATCC 23457 tRNA/rRNA methyltransferase SpoU YP_002731917.1 167620 R 546272 CDS YP_002731918.1 225851685 7676583 complement(169767..170090) 1 NC_012441.1 hypothetical protein 170090 7676583 BMEA_A0158 Brucella melitensis ATCC 23457 hypothetical protein YP_002731918.1 169767 R 546272 CDS YP_002731919.1 225851686 7676584 complement(170100..170384) 1 NC_012441.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 170384 ihfB 7676584 ihfB Brucella melitensis ATCC 23457 integration host factor subunit beta YP_002731919.1 170100 R 546272 CDS YP_002731920.1 225851687 7676585 complement(170431..171414) 1 NC_012441.1 signal peptide peptidase SppA, 36K type 171414 sppA 7676585 sppA Brucella melitensis ATCC 23457 signal peptide peptidase SppA, 36K type YP_002731920.1 170431 R 546272 CDS YP_002731921.1 225851688 7676586 171876..172598 1 NC_012441.1 hypothetical protein 172598 7676586 BMEA_A0161 Brucella melitensis ATCC 23457 hypothetical protein YP_002731921.1 171876 D 546272 CDS YP_002731922.1 225851689 7676587 172922..173536 1 NC_012441.1 OstA-like protein 173536 7676587 BMEA_A0162 Brucella melitensis ATCC 23457 OstA-like protein YP_002731922.1 172922 D 546272 CDS YP_002731923.1 225851690 7676588 173548..174381 1 NC_012441.1 ABC transporter ATP-binding protein 174381 7676588 BMEA_A0163 Brucella melitensis ATCC 23457 ABC transporter ATP-binding protein YP_002731923.1 173548 D 546272 CDS YP_002731924.1 225851691 7676589 174677..176179 1 NC_012441.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 176179 rpoN 7676589 rpoN Brucella melitensis ATCC 23457 RNA polymerase factor sigma-54 YP_002731924.1 174677 D 546272 CDS YP_002731925.1 225851692 7676590 complement(176325..176693) 1 NC_012441.1 hypothetical protein 176693 7676590 BMEA_A0165 Brucella melitensis ATCC 23457 hypothetical protein YP_002731925.1 176325 R 546272 CDS YP_002731926.1 225851693 7676591 176929..177522 1 NC_012441.1 ribosomal subunit interface protein 177522 yfiA 7676591 yfiA Brucella melitensis ATCC 23457 ribosomal subunit interface protein YP_002731926.1 176929 D 546272 CDS YP_002731927.1 225851694 7676592 177625..178089 1 NC_012441.1 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 178089 ptsN 7676592 ptsN Brucella melitensis ATCC 23457 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002731927.1 177625 D 546272 CDS YP_002731928.1 225851695 7676593 complement(178170..178415) 1 NC_012441.1 hypothetical protein 178415 7676593 BMEA_A0168 Brucella melitensis ATCC 23457 hypothetical protein YP_002731928.1 178170 R 546272 CDS YP_002731929.1 225851696 7676594 complement(178521..178943) 1 NC_012441.1 small heat shock protein hspD 178943 7676594 BMEA_A0169 Brucella melitensis ATCC 23457 small heat shock protein hspD YP_002731929.1 178521 R 546272 CDS YP_002731930.1 225851697 7676595 complement(179034..179234) 1 NC_012441.1 hypothetical protein 179234 7676595 BMEA_A0170 Brucella melitensis ATCC 23457 hypothetical protein YP_002731930.1 179034 R 546272 CDS YP_002731931.1 225851698 7677395 complement(179215..179829) 1 NC_012441.1 hypothetical protein 179829 7677395 BMEA_A0171 Brucella melitensis ATCC 23457 hypothetical protein YP_002731931.1 179215 R 546272 CDS YP_002731932.1 225851699 7677396 179817..180563 1 NC_012441.1 endonuclease III 180563 nth 7677396 nth Brucella melitensis ATCC 23457 endonuclease III YP_002731932.1 179817 D 546272 CDS YP_002731933.1 225851700 7677397 complement(180604..181317) 1 NC_012441.1 putative role in sulfur assimilation; CysZ-like protein 181317 7677397 BMEA_A0173 Brucella melitensis ATCC 23457 CysZ-like protein YP_002731933.1 180604 R 546272 CDS YP_002731934.1 225851701 7677398 complement(181314..181574) 1 NC_012441.1 hypothetical protein 181574 7677398 BMEA_A0174 Brucella melitensis ATCC 23457 hypothetical protein YP_002731934.1 181314 R 546272 CDS YP_002731935.1 225851702 7677399 181577..182569 1 NC_012441.1 fructokinase-2 182569 7677399 BMEA_A0175 Brucella melitensis ATCC 23457 fructokinase-2 YP_002731935.1 181577 D 546272 CDS YP_002731936.1 225851703 7677400 complement(182588..183244) 1 NC_012441.1 hypothetical protein 183244 7677400 BMEA_A0176 Brucella melitensis ATCC 23457 hypothetical protein YP_002731936.1 182588 R 546272 CDS YP_002731937.1 225851704 7677401 complement(183377..184069) 1 NC_012441.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 184069 7677401 BMEA_A0177 Brucella melitensis ATCC 23457 heat shock protein GrpE YP_002731937.1 183377 R 546272 CDS YP_002731938.1 225851705 7677402 complement(184175..185245) 1 NC_012441.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 185245 hrcA 7677402 hrcA Brucella melitensis ATCC 23457 heat-inducible transcription repressor YP_002731938.1 184175 R 546272 CDS YP_002731939.1 225851706 7677403 185467..186183 1 NC_012441.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 186183 rph 7677403 rph Brucella melitensis ATCC 23457 ribonuclease PH YP_002731939.1 185467 D 546272 CDS YP_002731940.1 225851707 7677405 186763..187425 1 NC_012441.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 187425 rdgB 7677405 rdgB Brucella melitensis ATCC 23457 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002731940.1 186763 D 546272 CDS YP_002731941.1 225851708 7677406 187422..188636 1 NC_012441.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 188636 7677406 BMEA_A0183 Brucella melitensis ATCC 23457 coproporphyrinogen III oxidase YP_002731941.1 187422 D 546272 CDS YP_002731942.1 225851709 7677407 188648..189559 1 NC_012441.1 hypothetical protein 189559 7677407 BMEA_A0184 Brucella melitensis ATCC 23457 hypothetical protein YP_002731942.1 188648 D 546272 CDS YP_002731943.1 225851710 7677408 189556..189936 1 NC_012441.1 hypothetical protein 189936 7677408 BMEA_A0185 Brucella melitensis ATCC 23457 hypothetical protein YP_002731943.1 189556 D 546272 CDS YP_002731944.1 225851711 7677409 190162..191568 1 NC_012441.1 uroporphyrin-III C-methyltransferase 191568 cobA 7677409 cobA Brucella melitensis ATCC 23457 uroporphyrin-III C-methyltransferase YP_002731944.1 190162 D 546272 CDS YP_002731945.1 225851712 7677410 191586..191888 1 NC_012441.1 hypothetical protein 191888 7677410 BMEA_A0187 Brucella melitensis ATCC 23457 hypothetical protein YP_002731945.1 191586 D 546272 CDS YP_002731946.1 225851713 7677411 191909..193579 1 NC_012441.1 sulfite reductase ferredoxin 193579 7677411 BMEA_A0188 Brucella melitensis ATCC 23457 sulfite reductase ferredoxin YP_002731946.1 191909 D 546272 CDS YP_002731947.1 225851714 7677412 193569..194327 1 NC_012441.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 194327 cysH 7677412 cysH Brucella melitensis ATCC 23457 phosphoadenosine phosphosulfate reductase YP_002731947.1 193569 D 546272 CDS YP_002731948.1 225851715 7677413 194380..194904 1 NC_012441.1 hypothetical protein 194904 7677413 BMEA_A0190 Brucella melitensis ATCC 23457 hypothetical protein YP_002731948.1 194380 D 546272 CDS YP_002731949.1 225851716 7677414 194972..195265 1 NC_012441.1 stress responsive alpha-beta barrel domain-containing protein 195265 7677414 BMEA_A0191 Brucella melitensis ATCC 23457 stress responsive alpha-beta barrel domain-containing protein YP_002731949.1 194972 D 546272 CDS YP_002731950.1 225851717 7677415 complement(195266..195844) 1 NC_012441.1 methylated-DNA--protein-cysteine methyltransferase 195844 7677415 BMEA_A0192 Brucella melitensis ATCC 23457 methylated-DNA--protein-cysteine methyltransferase YP_002731950.1 195266 R 546272 CDS YP_002731951.1 225851718 7677416 196102..196347 1 NC_012441.1 hypothetical protein 196347 7677416 BMEA_A0194 Brucella melitensis ATCC 23457 hypothetical protein YP_002731951.1 196102 D 546272 CDS YP_002731952.1 225851719 7677417 complement(196400..196789) 1 NC_012441.1 BA14K family protein 196789 7677417 BMEA_A0195 Brucella melitensis ATCC 23457 BA14K family protein YP_002731952.1 196400 R 546272 CDS YP_002731953.1 225851720 7677418 197103..200888 1 NC_012441.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 200888 metH 7677418 metH Brucella melitensis ATCC 23457 B12-dependent methionine synthase YP_002731953.1 197103 D 546272 CDS YP_002731954.1 225851721 7677419 201200..201916 1 NC_012441.1 transcriptional activator protein solR 201916 7677419 BMEA_A0198 Brucella melitensis ATCC 23457 transcriptional activator protein solR YP_002731954.1 201200 D 546272 CDS YP_002731955.1 225851722 7677420 202031..203401 1 NC_012441.1 aminotransferase 203401 7677420 BMEA_A0199 Brucella melitensis ATCC 23457 aminotransferase YP_002731955.1 202031 D 546272 CDS YP_002731956.1 225851723 7677421 complement(203483..203791) 1 NC_012441.1 hypothetical protein 203791 7677421 BMEA_A0200 Brucella melitensis ATCC 23457 hypothetical protein YP_002731956.1 203483 R 546272 CDS YP_002731957.1 225851724 7677422 203804..204706 1 NC_012441.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 204706 cysD 7677422 cysD Brucella melitensis ATCC 23457 sulfate adenylyltransferase subunit 2 YP_002731957.1 203804 D 546272 CDS YP_002731958.1 225851725 7677423 204706..206640 1 NC_012441.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 206640 cysN 7677423 cysN Brucella melitensis ATCC 23457 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase YP_002731958.1 204706 D 546272 CDS YP_002731959.1 225851726 7677424 206643..207488 1 NC_012441.1 3'(2'),5'-bisphosphate nucleotidase 207488 cysQ 7677424 cysQ Brucella melitensis ATCC 23457 3'(2'),5'-bisphosphate nucleotidase YP_002731959.1 206643 D 546272 CDS YP_002731960.1 225851727 7677426 complement(207750..208556) 1 NC_012441.1 fumarate nitrate reduction regulatory protein 208556 7677426 BMEA_A0205 Brucella melitensis ATCC 23457 fumarate nitrate reduction regulatory protein YP_002731960.1 207750 R 546272 CDS YP_002731961.1 225851728 7677427 208754..209491 1 NC_012441.1 monoamine regulon transcriptional regulator 209491 7677427 BMEA_A0206 Brucella melitensis ATCC 23457 monoamine regulon transcriptional regulator YP_002731961.1 208754 D 546272 CDS YP_002731962.1 225851729 7677428 209466..209597 1 NC_012441.1 hypothetical protein 209597 7677428 BMEA_A0207 Brucella melitensis ATCC 23457 hypothetical protein YP_002731962.1 209466 D 546272 CDS YP_002731963.1 225851730 7677429 209819..210610 1 NC_012441.1 DeoR family transcriptional regulator 210610 7677429 BMEA_A0208 Brucella melitensis ATCC 23457 DeoR family transcriptional regulator YP_002731963.1 209819 D 546272 CDS YP_002731964.1 225851731 7677430 210692..212194 1 NC_012441.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 212194 7677430 BMEA_A0209 Brucella melitensis ATCC 23457 glycerol-3-phosphate dehydrogenase YP_002731964.1 210692 D 546272 CDS YP_002731965.1 225851732 7677431 212080..213381 1 NC_012441.1 Fis family transcriptional regulator 213381 7677431 BMEA_A0210 Brucella melitensis ATCC 23457 Fis family transcriptional regulator YP_002731965.1 212080 D 546272 CDS YP_002731966.1 225851733 7677432 213530..215047 1 NC_012441.1 EPTC-inducible aldehyde dehydrogenase 215047 7677432 BMEA_A0211 Brucella melitensis ATCC 23457 EPTC-inducible aldehyde dehydrogenase YP_002731966.1 213530 D 546272 CDS YP_002731967.1 225851734 7677433 215528..216562 1 NC_012441.1 alcohol dehydrogenase 216562 7677433 BMEA_A0212 Brucella melitensis ATCC 23457 alcohol dehydrogenase YP_002731967.1 215528 D 546272 CDS YP_002731968.1 225851735 7677434 216584..216985 1 NC_012441.1 hypothetical protein 216985 7677434 BMEA_A0213 Brucella melitensis ATCC 23457 hypothetical protein YP_002731968.1 216584 D 546272 CDS YP_002731969.1 225851736 7677435 217047..218069 1 NC_012441.1 alanine racemase 218069 7677435 BMEA_A0214 Brucella melitensis ATCC 23457 alanine racemase YP_002731969.1 217047 D 546272 CDS YP_002731970.1 225851737 7677437 complement(220427..220591) 1 NC_012441.1 hypothetical protein 220591 7677437 BMEA_A0216 Brucella melitensis ATCC 23457 hypothetical protein YP_002731970.1 220427 R 546272 CDS YP_002731971.1 225851738 7677438 220580..222013 1 NC_012441.1 aldehyde dehydrogenase family protein 222013 7677438 BMEA_A0217 Brucella melitensis ATCC 23457 aldehyde dehydrogenase family protein YP_002731971.1 220580 D 546272 CDS YP_002731972.1 225851739 7677440 complement(222830..223528) 1 NC_012441.1 transcriptional activator, TenA family protein 223528 7677440 BMEA_A0219 Brucella melitensis ATCC 23457 transcriptional activator, TenA family protein YP_002731972.1 222830 R 546272 CDS YP_002731973.1 225851740 7677441 complement(223525..224493) 1 NC_012441.1 NMT1/THI5 like domain-containing protein 224493 7677441 BMEA_A0220 Brucella melitensis ATCC 23457 NMT1/THI5 like domain-containing protein YP_002731973.1 223525 R 546272 CDS YP_002731974.1 225851741 7677442 complement(224517..225128) 1 NC_012441.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 225128 7677442 BMEA_A0221 Brucella melitensis ATCC 23457 thiamine-phosphate pyrophosphorylase YP_002731974.1 224517 R 546272 CDS YP_002731975.1 225851742 7677443 complement(225125..225895) 1 NC_012441.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 225895 7677443 BMEA_A0222 Brucella melitensis ATCC 23457 thiazole synthase YP_002731975.1 225125 R 546272 CDS YP_002731976.1 225851743 7677444 complement(225897..226094) 1 NC_012441.1 thiamine biosynthesis protein ThiS 226094 thiS 7677444 thiS Brucella melitensis ATCC 23457 thiamine biosynthesis protein ThiS YP_002731976.1 225897 R 546272 CDS YP_002731977.1 225851744 7677445 complement(226091..227095) 1 NC_012441.1 glycine oxidase ThiO 227095 thiO 7677445 thiO Brucella melitensis ATCC 23457 glycine oxidase ThiO YP_002731977.1 226091 R 546272 CDS YP_002731978.1 225851745 7677446 complement(227095..227970) 1 NC_012441.1 phosphomethylpyrimidine kinase 227970 thiD 7677446 thiD Brucella melitensis ATCC 23457 phosphomethylpyrimidine kinase YP_002731978.1 227095 R 546272 CDS YP_002731979.1 225851746 7677447 228399..230510 1 NC_012441.1 diguanylate cyclase GGDEF domain-containing protein 230510 7677447 BMEA_A0227 Brucella melitensis ATCC 23457 diguanylate cyclase GGDEF domain-containing protein YP_002731979.1 228399 D 546272 CDS YP_002731980.1 225851747 7677448 230609..233089 1 NC_012441.1 heavy metal translocating P-type ATPase 233089 7677448 BMEA_A0228 Brucella melitensis ATCC 23457 heavy metal translocating P-type ATPase YP_002731980.1 230609 D 546272 CDS YP_002731981.1 225851748 7677449 complement(233069..233518) 1 NC_012441.1 Cu (I) responsive transcriptional regulator 233518 cueR 7677449 cueR Brucella melitensis ATCC 23457 Cu (I) responsive transcriptional regulator YP_002731981.1 233069 R 546272 CDS YP_002731982.1 225851749 7677450 complement(233624..234370) 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 234370 7677450 BMEA_A0230 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002731982.1 233624 R 546272 CDS YP_002731983.1 225851750 7677451 complement(234367..235305) 1 NC_012441.1 ABC transporter 235305 7677451 BMEA_A0231 Brucella melitensis ATCC 23457 ABC transporter YP_002731983.1 234367 R 546272 CDS YP_002731984.1 225851751 7677452 complement(235302..236462) 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 236462 7677452 BMEA_A0232 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002731984.1 235302 R 546272 CDS YP_002731985.1 225851752 7677453 complement(236535..237602) 1 NC_012441.1 glycine/betaine ABC transporter substrate-binding protein 237602 7677453 BMEA_A0233 Brucella melitensis ATCC 23457 glycine/betaine ABC transporter substrate-binding protein YP_002731985.1 236535 R 546272 CDS YP_002731986.1 225851753 7677454 complement(237635..238300) 1 NC_012441.1 hypothetical protein 238300 7677454 BMEA_A0234 Brucella melitensis ATCC 23457 hypothetical protein YP_002731986.1 237635 R 546272 CDS YP_002731987.1 225851754 7677455 complement(238589..239854) 1 NC_012441.1 glutamate dehydrogenase 239854 7677455 BMEA_A0235 Brucella melitensis ATCC 23457 glutamate dehydrogenase YP_002731987.1 238589 R 546272 CDS YP_002731988.1 225851755 7677456 240045..240212 1 NC_012441.1 hypothetical protein 240212 7677456 BMEA_A0236 Brucella melitensis ATCC 23457 hypothetical protein YP_002731988.1 240045 D 546272 CDS YP_002731989.1 225851756 7677457 240181..241434 1 NC_012441.1 sarcosine oxidase subunit beta 241434 7677457 BMEA_A0237 Brucella melitensis ATCC 23457 sarcosine oxidase subunit beta YP_002731989.1 240181 D 546272 CDS YP_002731990.1 225851757 7677458 241453..241758 1 NC_012441.1 sarcosine oxidase subunit delta 241758 7677458 BMEA_A0238 Brucella melitensis ATCC 23457 sarcosine oxidase subunit delta YP_002731990.1 241453 D 546272 CDS YP_002731991.1 225851758 7677459 241758..244757 1 NC_012441.1 sarcosine oxidase subunit alpha 244757 7677459 BMEA_A0239 Brucella melitensis ATCC 23457 sarcosine oxidase subunit alpha YP_002731991.1 241758 D 546272 CDS YP_002731992.1 225851759 7677460 244768..245322 1 NC_012441.1 sarcosine oxidase gamma subunit 245322 7677460 BMEA_A0240 Brucella melitensis ATCC 23457 sarcosine oxidase gamma subunit YP_002731992.1 244768 D 546272 CDS YP_002731993.1 225851760 7677461 complement(245375..246223) 1 NC_012441.1 amidohydrolase 2 246223 7677461 BMEA_A0241 Brucella melitensis ATCC 23457 amidohydrolase 2 YP_002731993.1 245375 R 546272 CDS YP_002731994.1 225851761 7677462 complement(246281..247075) 1 NC_012441.1 HTH-type transcriptional repressor AllR 247075 7677462 BMEA_A0242 Brucella melitensis ATCC 23457 HTH-type transcriptional repressor AllR YP_002731994.1 246281 R 546272 CDS YP_002731995.1 225851762 7677463 247233..248552 1 NC_012441.1 extracellular solute-binding protein 248552 7677463 BMEA_A0243 Brucella melitensis ATCC 23457 extracellular solute-binding protein YP_002731995.1 247233 D 546272 CDS YP_002731996.1 225851763 7677464 248613..249536 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 249536 7677464 BMEA_A0244 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002731996.1 248613 D 546272 CDS YP_002731997.1 225851764 7677465 249539..250414 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 250414 7677465 BMEA_A0245 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002731997.1 249539 D 546272 CDS YP_002731998.1 225851765 7677466 250422..251513 1 NC_012441.1 lactose transport ATP-binding protein lacK 251513 7677466 BMEA_A0246 Brucella melitensis ATCC 23457 lactose transport ATP-binding protein lacK YP_002731998.1 250422 D 546272 CDS YP_002731999.1 225851766 7677467 251516..252634 1 NC_012441.1 mandelate racemase 252634 7677467 BMEA_A0247 Brucella melitensis ATCC 23457 mandelate racemase YP_002731999.1 251516 D 546272 CDS YP_002732000.1 225851767 7677468 252631..252975 1 NC_012441.1 hypothetical protein 252975 7677468 BMEA_A0248 Brucella melitensis ATCC 23457 hypothetical protein YP_002732000.1 252631 D 546272 CDS YP_002732001.1 225851768 7677469 252968..254047 1 NC_012441.1 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 254047 7677469 BMEA_A0249 Brucella melitensis ATCC 23457 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase YP_002732001.1 252968 D 546272 CDS YP_002732002.1 225851769 7677470 254050..254148 1 NC_012441.1 hypothetical protein 254148 7677470 BMEA_A0250 Brucella melitensis ATCC 23457 hypothetical protein YP_002732002.1 254050 D 546272 CDS YP_002732003.1 225851770 7677471 254152..254886 1 NC_012441.1 short-chain dehydrogenase/reductase SDR 254886 7677471 BMEA_A0251 Brucella melitensis ATCC 23457 short-chain dehydrogenase/reductase SDR YP_002732003.1 254152 D 546272 CDS YP_002732004.1 225851771 7677472 254927..255772 1 NC_012441.1 fumarylacetoacetate hydrolase domain-containing protein 2 255772 7677472 BMEA_A0252 Brucella melitensis ATCC 23457 fumarylacetoacetate hydrolase domain-containing protein 2 YP_002732004.1 254927 D 546272 CDS YP_002732005.1 225851772 7677473 255786..257063 1 NC_012441.1 mandelate racemase/muconate lactonizing enzyme domain-containing protein 257063 7677473 BMEA_A0253 Brucella melitensis ATCC 23457 mandelate racemase/muconate lactonizing enzyme domain-containing protein YP_002732005.1 255786 D 546272 CDS YP_002732006.1 225851773 7677474 complement(257224..257307) 1 NC_012441.1 hypothetical protein 257307 7677474 BMEA_A0254 Brucella melitensis ATCC 23457 hypothetical protein YP_002732006.1 257224 R 546272 CDS YP_002732007.1 225851774 7677475 complement(257462..258013) 1 NC_012441.1 hypothetical protein 258013 7677475 BMEA_A0255 Brucella melitensis ATCC 23457 hypothetical protein YP_002732007.1 257462 R 546272 CDS YP_002732008.1 225851775 7677964 complement(258842..258967) 1 NC_012441.1 hypothetical protein 258967 7677964 BMEA_A0256 Brucella melitensis ATCC 23457 hypothetical protein YP_002732008.1 258842 R 546272 CDS YP_002732009.1 225851776 7677965 259204..260400 1 NC_012441.1 putative integrase DNA protein 260400 7677965 BMEA_A0257 Brucella melitensis ATCC 23457 putative integrase DNA protein YP_002732009.1 259204 D 546272 CDS YP_002732010.1 225851777 7677966 complement(260538..260810) 1 NC_012441.1 hypothetical protein 260810 7677966 BMEA_A0258 Brucella melitensis ATCC 23457 hypothetical protein YP_002732010.1 260538 R 546272 CDS YP_002732011.1 225851778 7677967 260911..261129 1 NC_012441.1 hypothetical protein 261129 7677967 BMEA_A0259 Brucella melitensis ATCC 23457 hypothetical protein YP_002732011.1 260911 D 546272 CDS YP_002732012.1 225851779 7677968 261336..261650 1 NC_012441.1 hypothetical protein 261650 7677968 BMEA_A0260 Brucella melitensis ATCC 23457 hypothetical protein YP_002732012.1 261336 D 546272 CDS YP_002732013.1 225851780 7677969 261647..262528 1 NC_012441.1 hypothetical protein 262528 7677969 BMEA_A0261 Brucella melitensis ATCC 23457 hypothetical protein YP_002732013.1 261647 D 546272 CDS YP_002732014.1 225851781 7677970 262525..264027 1 NC_012441.1 hypothetical protein 264027 7677970 BMEA_A0262 Brucella melitensis ATCC 23457 hypothetical protein YP_002732014.1 262525 D 546272 CDS YP_002732015.1 225851782 7677971 264054..264641 1 NC_012441.1 hypothetical protein 264641 7677971 BMEA_A0263 Brucella melitensis ATCC 23457 hypothetical protein YP_002732015.1 264054 D 546272 CDS YP_002732016.1 225851783 7677972 264634..264798 1 NC_012441.1 hypothetical protein 264798 7677972 BMEA_A0264 Brucella melitensis ATCC 23457 hypothetical protein YP_002732016.1 264634 D 546272 CDS YP_002732017.1 225851784 7677973 264795..265811 1 NC_012441.1 hypothetical protein 265811 7677973 BMEA_A0265 Brucella melitensis ATCC 23457 hypothetical protein YP_002732017.1 264795 D 546272 CDS YP_002732018.1 225851785 7677974 265913..266122 1 NC_012441.1 hypothetical protein 266122 7677974 BMEA_A0266 Brucella melitensis ATCC 23457 hypothetical protein YP_002732018.1 265913 D 546272 CDS YP_002732019.1 225851786 7677976 268236..270281 1 NC_012441.1 elastin 270281 7677976 BMEA_A0268 Brucella melitensis ATCC 23457 elastin YP_002732019.1 268236 D 546272 CDS YP_002732020.1 225851787 7677977 complement(270264..270446) 1 NC_012441.1 hypothetical protein 270446 7677977 BMEA_A0269 Brucella melitensis ATCC 23457 hypothetical protein YP_002732020.1 270264 R 546272 CDS YP_002732021.1 225851788 7677978 270482..270787 1 NC_012441.1 hypothetical protein 270787 7677978 BMEA_A0270 Brucella melitensis ATCC 23457 hypothetical protein YP_002732021.1 270482 D 546272 CDS YP_002732022.1 225851789 7677979 271886..272092 1 NC_012441.1 hypothetical protein 272092 7677979 BMEA_A0271 Brucella melitensis ATCC 23457 hypothetical protein YP_002732022.1 271886 D 546272 CDS YP_002732023.1 225851790 7677980 complement(273999..274178) 1 NC_012441.1 hypothetical protein 274178 7677980 BMEA_A0272 Brucella melitensis ATCC 23457 hypothetical protein YP_002732023.1 273999 R 546272 CDS YP_002732024.1 225851791 7677981 complement(275310..275555) 1 NC_012441.1 helix-turn-helix domain-containing protein 275555 7677981 BMEA_A0273 Brucella melitensis ATCC 23457 helix-turn-helix domain-containing protein YP_002732024.1 275310 R 546272 CDS YP_002732025.1 225851792 7677982 275633..275878 1 NC_012441.1 hypothetical protein 275878 7677982 BMEA_A0274 Brucella melitensis ATCC 23457 hypothetical protein YP_002732025.1 275633 D 546272 CDS YP_002732026.1 225851793 7677983 275944..276234 1 NC_012441.1 hypothetical protein 276234 7677983 BMEA_A0275 Brucella melitensis ATCC 23457 hypothetical protein YP_002732026.1 275944 D 546272 CDS YP_002732027.1 225851794 7677984 276231..276770 1 NC_012441.1 hypothetical protein 276770 7677984 BMEA_A0276 Brucella melitensis ATCC 23457 hypothetical protein YP_002732027.1 276231 D 546272 CDS YP_002732028.1 225851795 7677985 276871..277044 1 NC_012441.1 hypothetical protein 277044 7677985 BMEA_A0277 Brucella melitensis ATCC 23457 hypothetical protein YP_002732028.1 276871 D 546272 CDS YP_002732029.1 225851796 7677986 277041..277649 1 NC_012441.1 hypothetical protein 277649 7677986 BMEA_A0278 Brucella melitensis ATCC 23457 hypothetical protein YP_002732029.1 277041 D 546272 CDS YP_002732030.1 225851797 7677987 complement(278349..279176) 1 NC_012441.1 hypothetical protein 279176 7677987 BMEA_A0279 Brucella melitensis ATCC 23457 hypothetical protein YP_002732030.1 278349 R 546272 CDS YP_002732031.1 225851798 7677988 279415..279549 1 NC_012441.1 hypothetical protein 279549 7677988 BMEA_A0280 Brucella melitensis ATCC 23457 hypothetical protein YP_002732031.1 279415 D 546272 CDS YP_002732032.1 225851799 7677990 complement(280156..280371) 1 NC_012441.1 zinc-binding protein 280371 7677990 BMEA_A0282 Brucella melitensis ATCC 23457 zinc-binding protein YP_002732032.1 280156 R 546272 CDS YP_002732033.1 225851800 7677991 complement(280381..281007) 1 NC_012441.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 281007 maf 7677991 maf Brucella melitensis ATCC 23457 Maf-like protein YP_002732033.1 280381 R 546272 CDS YP_002732034.1 225851801 7677992 complement(281041..281259) 1 NC_012441.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 281259 infA 7677992 infA Brucella melitensis ATCC 23457 translation initiation factor IF-1 YP_002732034.1 281041 R 546272 CDS YP_002732035.1 225851802 7677993 complement(281371..281844) 1 NC_012441.1 protein tyrosine phosphatase 281844 7677993 BMEA_A0285 Brucella melitensis ATCC 23457 protein tyrosine phosphatase YP_002732035.1 281371 R 546272 CDS YP_002732036.1 225851803 7677994 complement(281851..282333) 1 NC_012441.1 hypothetical protein 282333 7677994 BMEA_A0286 Brucella melitensis ATCC 23457 hypothetical protein YP_002732036.1 281851 R 546272 CDS YP_002732037.1 225851804 7677995 complement(282340..283632) 1 NC_012441.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 283632 hisD 7677995 hisD Brucella melitensis ATCC 23457 histidinol dehydrogenase YP_002732037.1 282340 R 546272 CDS YP_002732038.1 225851805 7677996 complement(283707..284147) 1 NC_012441.1 hypothetical protein 284147 7677996 BMEA_A0288 Brucella melitensis ATCC 23457 hypothetical protein YP_002732038.1 283707 R 546272 CDS YP_002732039.1 225851806 7677997 complement(284418..285707) 1 NC_012441.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 285707 murA 7677997 murA Brucella melitensis ATCC 23457 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002732039.1 284418 R 546272 CDS YP_002732040.1 225851807 7677998 complement(285930..286109) 1 NC_012441.1 hypothetical protein 286109 7677998 BMEA_A0290 Brucella melitensis ATCC 23457 hypothetical protein YP_002732040.1 285930 R 546272 CDS YP_002732041.1 225851808 7678000 286412..288178 1 NC_012441.1 hypothetical protein 288178 7678000 BMEA_A0292 Brucella melitensis ATCC 23457 hypothetical protein YP_002732041.1 286412 D 546272 CDS YP_002732042.1 225851809 7678001 288273..288695 1 NC_012441.1 BRO family protein 288695 7678001 BMEA_A0293 Brucella melitensis ATCC 23457 BRO family protein YP_002732042.1 288273 D 546272 CDS YP_002732043.1 225851810 7678002 289064..289213 1 NC_012441.1 hypothetical protein 289213 7678002 BMEA_A0294 Brucella melitensis ATCC 23457 hypothetical protein YP_002732043.1 289064 D 546272 CDS YP_002732044.1 225851811 7678003 289493..290110 1 NC_012441.1 DNA-invertase 290110 7678003 BMEA_A0295 Brucella melitensis ATCC 23457 DNA-invertase YP_002732044.1 289493 D 546272 CDS YP_002732045.1 225851812 7678004 290668..292032 1 NC_012441.1 hypothetical protein 292032 7678004 BMEA_A0296 Brucella melitensis ATCC 23457 hypothetical protein YP_002732045.1 290668 D 546272 CDS YP_002732046.1 225851813 7678005 complement(293335..293619) 1 NC_012441.1 hypothetical protein 293619 7678005 BMEA_A0297 Brucella melitensis ATCC 23457 hypothetical protein YP_002732046.1 293335 R 546272 CDS YP_002732047.1 225851814 7678006 complement(293733..293996) 1 NC_012441.1 hypothetical protein 293996 7678006 BMEA_A0298 Brucella melitensis ATCC 23457 hypothetical protein YP_002732047.1 293733 R 546272 CDS YP_002732048.1 225851815 7678007 294080..294469 1 NC_012441.1 hypothetical protein 294469 7678007 BMEA_A0299 Brucella melitensis ATCC 23457 hypothetical protein YP_002732048.1 294080 D 546272 CDS YP_002732049.1 225851816 7678008 295061..295903 1 NC_012441.1 urease accessory protein UreD 295903 7678008 BMEA_A0300 Brucella melitensis ATCC 23457 urease accessory protein UreD YP_002732049.1 295061 D 546272 CDS YP_002732050.1 225851817 7678009 296056..296358 1 NC_012441.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 296358 ureA 7678009 ureA Brucella melitensis ATCC 23457 urease subunit gamma YP_002732050.1 296056 D 546272 CDS YP_002732051.1 225851818 7678010 296525..296830 1 NC_012441.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 296830 ureB 7678010 ureB Brucella melitensis ATCC 23457 urease subunit beta YP_002732051.1 296525 D 546272 CDS YP_002732052.1 225851819 7678011 296849..298561 1 NC_012441.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 298561 ureC 7678011 ureC Brucella melitensis ATCC 23457 urease subunit alpha YP_002732052.1 296849 D 546272 CDS YP_002732053.1 225851820 7678012 298577..299065 1 NC_012441.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 299065 7678012 BMEA_A0304 Brucella melitensis ATCC 23457 urease accessory protein UreE YP_002732053.1 298577 D 546272 CDS YP_002732054.1 225851821 7678013 299037..299723 1 NC_012441.1 urease accessory protein UreF 299723 7678013 BMEA_A0305 Brucella melitensis ATCC 23457 urease accessory protein UreF YP_002732054.1 299037 D 546272 CDS YP_002732055.1 225851822 7678014 299720..300346 1 NC_012441.1 urease accessory protein UreG 300346 ureG 7678014 ureG Brucella melitensis ATCC 23457 urease accessory protein UreG YP_002732055.1 299720 D 546272 CDS YP_002732056.1 225851823 7678016 complement(300703..302328) 1 NC_012441.1 integral membrane sensor signal transduction histidine kinase 302328 7678016 BMEA_A0308 Brucella melitensis ATCC 23457 integral membrane sensor signal transduction histidine kinase YP_002732056.1 300703 R 546272 CDS YP_002732057.1 225851824 7678017 302613..303764 1 NC_012441.1 RND family efflux transporter 303764 7678017 BMEA_A0310 Brucella melitensis ATCC 23457 RND family efflux transporter YP_002732057.1 302613 D 546272 CDS YP_002732058.1 225851825 7678018 303779..306910 1 NC_012441.1 acriflavin resistance protein 306910 7678018 BMEA_A0311 Brucella melitensis ATCC 23457 acriflavin resistance protein YP_002732058.1 303779 D 546272 CDS YP_002732059.1 225851826 7678019 complement(307033..308502) 1 NC_012441.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 308502 hydA 7678019 hydA Brucella melitensis ATCC 23457 phenylhydantoinase YP_002732059.1 307033 R 546272 CDS YP_002732060.1 225851827 7678020 complement(308554..309801) 1 NC_012441.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 309801 7678020 BMEA_A0313 Brucella melitensis ATCC 23457 allantoate amidohydrolase YP_002732060.1 308554 R 546272 CDS YP_002732061.1 225851828 7678022 310700..311089 1 NC_012441.1 nudix domain-containing protein 311089 7678022 BMEA_A0315 Brucella melitensis ATCC 23457 nudix domain-containing protein YP_002732061.1 310700 D 546272 CDS YP_002732062.1 225851829 7678023 complement(311134..312444) 1 NC_012441.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 312444 7678023 BMEA_A0316 Brucella melitensis ATCC 23457 dihydropyrimidine dehydrogenase YP_002732062.1 311134 R 546272 CDS YP_002732063.1 225851830 7678024 complement(312448..313944) 1 NC_012441.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 313944 7678024 BMEA_A0317 Brucella melitensis ATCC 23457 putative oxidoreductase YP_002732063.1 312448 R 546272 CDS YP_002732064.1 225851831 7678025 complement(314132..314584) 1 NC_012441.1 carbon monoxide dehydrogenase subunit G 314584 7678025 BMEA_A0319 Brucella melitensis ATCC 23457 carbon monoxide dehydrogenase subunit G YP_002732064.1 314132 R 546272 CDS YP_002732065.1 225851832 7678026 314735..316384 1 NC_012441.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 316384 7678026 BMEA_A0320 Brucella melitensis ATCC 23457 glucose-6-phosphate isomerase YP_002732065.1 314735 D 546272 CDS YP_002732066.1 225851833 7678027 316518..317579 1 NC_012441.1 succinylglutamate desuccinylase/aspartoacylase 317579 7678027 BMEA_A0321 Brucella melitensis ATCC 23457 succinylglutamate desuccinylase/aspartoacylase YP_002732066.1 316518 D 546272 CDS YP_002732067.1 225851834 7678028 317576..318325 1 NC_012441.1 HAD-superfamily hydrolase 318325 7678028 BMEA_A0322 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002732067.1 317576 D 546272 CDS YP_002732068.1 225851835 7678029 complement(318298..319170) 1 NC_012441.1 hypothetical protein 319170 7678029 BMEA_A0323 Brucella melitensis ATCC 23457 hypothetical protein YP_002732068.1 318298 R 546272 CDS YP_002732069.1 225851836 7678030 complement(319196..320941) 1 NC_012441.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 320941 7678030 BMEA_A0324 Brucella melitensis ATCC 23457 long-chain-fatty-acid--CoA ligase YP_002732069.1 319196 R 546272 CDS YP_002732070.1 225851837 7678031 complement(321292..321921) 1 NC_012441.1 HTH-type transcriptional regulator TtgR 321921 7678031 BMEA_A0325 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator TtgR YP_002732070.1 321292 R 546272 CDS YP_002732071.1 225851838 7678032 322094..323287 1 NC_012441.1 RND family efflux transporter 323287 7678032 BMEA_A0327 Brucella melitensis ATCC 23457 RND family efflux transporter YP_002732071.1 322094 D 546272 CDS YP_002732072.1 225851839 7678033 323284..326439 1 NC_012441.1 hydrophobe/amphiphile efflux protein 326439 7678033 BMEA_A0328 Brucella melitensis ATCC 23457 hydrophobe/amphiphile efflux protein YP_002732072.1 323284 D 546272 CDS YP_002732073.1 225851840 7678034 complement(326550..326717) 1 NC_012441.1 hypothetical protein 326717 7678034 BMEA_A0329 Brucella melitensis ATCC 23457 hypothetical protein YP_002732073.1 326550 R 546272 CDS YP_002732074.1 225851841 7678035 complement(326938..327078) 1 NC_012441.1 hypothetical protein 327078 7678035 BMEA_A0330 Brucella melitensis ATCC 23457 hypothetical protein YP_002732074.1 326938 R 546272 CDS YP_002732075.1 225851842 7678036 complement(327147..327989) 1 NC_012441.1 family 3 extracellular solute-binding protein 327989 7678036 BMEA_A0331 Brucella melitensis ATCC 23457 family 3 extracellular solute-binding protein YP_002732075.1 327147 R 546272 CDS YP_002732076.1 225851843 7678037 328255..330147 1 NC_012441.1 xyloglucan glycosyltransferase 1 330147 7678037 BMEA_A0332 Brucella melitensis ATCC 23457 xyloglucan glycosyltransferase 1 YP_002732076.1 328255 D 546272 CDS YP_002732077.1 225851844 7678038 complement(330075..331034) 1 NC_012441.1 hypothetical protein 331034 7678038 BMEA_A0333 Brucella melitensis ATCC 23457 hypothetical protein YP_002732077.1 330075 R 546272 CDS YP_002732078.1 225851845 7678039 331167..332483 1 NC_012441.1 histidine kinase 332483 7678039 BMEA_A0334 Brucella melitensis ATCC 23457 histidine kinase YP_002732078.1 331167 D 546272 CDS YP_002732079.1 225851846 7678040 complement(332613..333155) 1 NC_012441.1 GcrA cell cycle regulator 333155 7678040 BMEA_A0335 Brucella melitensis ATCC 23457 GcrA cell cycle regulator YP_002732079.1 332613 R 546272 CDS YP_002732080.1 225851847 7678041 333759..334970 1 NC_012441.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase protein 334970 argD 7678041 argD Brucella melitensis ATCC 23457 acetylornithine transaminase protein YP_002732080.1 333759 D 546272 CDS YP_002732081.1 225851848 7678042 334975..335913 1 NC_012441.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 335913 argF 7678042 argF Brucella melitensis ATCC 23457 ornithine carbamoyltransferase YP_002732081.1 334975 D 546272 CDS YP_002732082.1 225851849 7678043 335915..336937 1 NC_012441.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 336937 7678043 BMEA_A0338 Brucella melitensis ATCC 23457 Hsp33-like chaperonin YP_002732082.1 335915 D 546272 CDS YP_002732083.1 225851850 7678044 complement(336978..337370) 1 NC_012441.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 337370 7678044 BMEA_A0339 Brucella melitensis ATCC 23457 ApaG protein YP_002732083.1 336978 R 546272 CDS YP_002732084.1 225851851 7677478 complement(337739..338935) 1 NC_012441.1 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; O-succinylhomoserine sulfhydrylase 338935 metZ 7677478 metZ Brucella melitensis ATCC 23457 O-succinylhomoserine sulfhydrylase YP_002732084.1 337739 R 546272 CDS YP_002732085.1 225851852 7677479 339362..340453 1 NC_012441.1 Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 340453 7677479 BMEA_A0343 Brucella melitensis ATCC 23457 2'-deoxycytidine 5'-triphosphate deaminase YP_002732085.1 339362 D 546272 CDS YP_002732086.1 225851853 7677480 340544..341560 1 NC_012441.1 AraC family transcriptional regulator 341560 7677480 BMEA_A0344 Brucella melitensis ATCC 23457 AraC family transcriptional regulator YP_002732086.1 340544 D 546272 CDS YP_002732087.1 225851854 7677481 341647..341913 1 NC_012441.1 hypothetical protein 341913 7677481 BMEA_A0345 Brucella melitensis ATCC 23457 hypothetical protein YP_002732087.1 341647 D 546272 CDS YP_002732088.1 225851855 7677482 341950..342432 1 NC_012441.1 hypothetical protein 342432 7677482 BMEA_A0346 Brucella melitensis ATCC 23457 hypothetical protein YP_002732088.1 341950 D 546272 CDS YP_002732089.1 225851856 7677483 342607..343974 1 NC_012441.1 MATE efflux family protein 343974 7677483 BMEA_A0347 Brucella melitensis ATCC 23457 MATE efflux family protein YP_002732089.1 342607 D 546272 CDS YP_002732090.1 225851857 7677484 complement(343976..345070) 1 NC_012441.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 345070 pyrD 7677484 pyrD Brucella melitensis ATCC 23457 dihydroorotate dehydrogenase 2 YP_002732090.1 343976 R 546272 CDS YP_002732091.1 225851858 7677485 complement(345067..345420) 1 NC_012441.1 hypothetical protein 345420 7677485 BMEA_A0349 Brucella melitensis ATCC 23457 hypothetical protein YP_002732091.1 345067 R 546272 CDS YP_002732092.1 225851859 7677486 345674..346129 1 NC_012441.1 hypothetical protein 346129 7677486 BMEA_A0351 Brucella melitensis ATCC 23457 hypothetical protein YP_002732092.1 345674 D 546272 CDS YP_002732093.1 225851860 7677487 complement(346220..347170) 1 NC_012441.1 proline iminopeptidase 347170 pip 7677487 pip Brucella melitensis ATCC 23457 proline iminopeptidase YP_002732093.1 346220 R 546272 CDS YP_002732094.1 225851861 7677488 347400..348041 1 NC_012441.1 LuxR family two component transcriptional regulator 348041 7677488 BMEA_A0353 Brucella melitensis ATCC 23457 LuxR family two component transcriptional regulator YP_002732094.1 347400 D 546272 CDS YP_002732095.1 225851862 7677489 complement(348078..351602) 1 NC_012441.1 integral membrane sensor hybrid histidine kinase 351602 7677489 BMEA_A0354 Brucella melitensis ATCC 23457 integral membrane sensor hybrid histidine kinase YP_002732095.1 348078 R 546272 CDS YP_002732096.1 225851863 7677490 complement(351887..352033) 1 NC_012441.1 hypothetical protein 352033 7677490 BMEA_A0355 Brucella melitensis ATCC 23457 hypothetical protein YP_002732096.1 351887 R 546272 CDS YP_002732097.1 225851864 7677491 352115..352531 1 NC_012441.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 352531 mscL 7677491 mscL Brucella melitensis ATCC 23457 large-conductance mechanosensitive channel YP_002732097.1 352115 D 546272 CDS YP_002732098.1 225851865 7677492 complement(352607..353884) 1 NC_012441.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 353884 hemA 7677492 hemA Brucella melitensis ATCC 23457 5-aminolevulinate synthase YP_002732098.1 352607 R 546272 CDS YP_002732099.1 225851866 7677493 complement(354030..354731) 1 NC_012441.1 polysaccharide deacetylase 354731 7677493 BMEA_A0358 Brucella melitensis ATCC 23457 polysaccharide deacetylase YP_002732099.1 354030 R 546272 CDS YP_002732100.1 225851867 7677494 complement(354740..355459) 1 NC_012441.1 glycosyltransferase 25 family protein 355459 7677494 BMEA_A0359 Brucella melitensis ATCC 23457 glycosyltransferase 25 family protein YP_002732100.1 354740 R 546272 CDS YP_002732101.1 225851868 7677496 complement(356354..356587) 1 NC_012441.1 hypothetical protein 356587 7677496 BMEA_A0361 Brucella melitensis ATCC 23457 hypothetical protein YP_002732101.1 356354 R 546272 CDS YP_002732102.1 225851869 7677497 complement(356630..357520) 1 NC_012441.1 LysR family transcriptional regulator 357520 7677497 BMEA_A0362 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002732102.1 356630 R 546272 CDS YP_002732103.1 225851870 7677498 357642..358061 1 NC_012441.1 LrgA family protein 358061 7677498 BMEA_A0363 Brucella melitensis ATCC 23457 LrgA family protein YP_002732103.1 357642 D 546272 CDS YP_002732104.1 225851871 7677499 358048..358755 1 NC_012441.1 LrgB family protein 358755 7677499 BMEA_A0364 Brucella melitensis ATCC 23457 LrgB family protein YP_002732104.1 358048 D 546272 CDS YP_002732105.1 225851872 7677500 358929..359264 1 NC_012441.1 hypothetical protein 359264 7677500 BMEA_A0365 Brucella melitensis ATCC 23457 hypothetical protein YP_002732105.1 358929 D 546272 CDS YP_002732106.1 225851873 7677501 359302..360543 1 NC_012441.1 hypothetical protein 360543 7677501 BMEA_A0366 Brucella melitensis ATCC 23457 hypothetical protein YP_002732106.1 359302 D 546272 CDS YP_002732107.1 225851874 7677502 360630..361511 1 NC_012441.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 361511 panC 7677502 panC Brucella melitensis ATCC 23457 pantoate--beta-alanine ligase YP_002732107.1 360630 D 546272 CDS YP_002732108.1 225851875 7677503 361513..362340 1 NC_012441.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 362340 panB 7677503 panB Brucella melitensis ATCC 23457 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002732108.1 361513 D 546272 CDS YP_002732109.1 225851876 7677504 complement(362537..363313) 1 NC_012441.1 oxidoreductase FAD-binding domain-containing protein 363313 7677504 BMEA_A0369 Brucella melitensis ATCC 23457 oxidoreductase FAD-binding domain-containing protein YP_002732109.1 362537 R 546272 CDS YP_002732110.1 225851877 7677505 363717..364070 1 NC_012441.1 hypothetical protein 364070 7677505 BMEA_A0370 Brucella melitensis ATCC 23457 hypothetical protein YP_002732110.1 363717 D 546272 CDS YP_002732111.1 225851878 7677506 364109..365206 1 NC_012441.1 carboxynorspermidine decarboxylase 365206 nspC 7677506 nspC Brucella melitensis ATCC 23457 carboxynorspermidine decarboxylase YP_002732111.1 364109 D 546272 CDS YP_002732112.1 225851879 7677507 365387..366628 1 NC_012441.1 hypothetical protein 366628 7677507 BMEA_A0372 Brucella melitensis ATCC 23457 hypothetical protein YP_002732112.1 365387 D 546272 CDS YP_002732113.1 225851880 7677508 complement(366644..366859) 1 NC_012441.1 hypothetical protein 366859 7677508 BMEA_A0373 Brucella melitensis ATCC 23457 hypothetical protein YP_002732113.1 366644 R 546272 CDS YP_002732114.1 225851881 7677509 complement(366884..367912) 1 NC_012441.1 proline racemase A 367912 7677509 BMEA_A0374 Brucella melitensis ATCC 23457 proline racemase A YP_002732114.1 366884 R 546272 CDS YP_002732115.1 225851882 7677510 368365..369780 1 NC_012441.1 MATE efflux family protein 369780 7677510 BMEA_A0375 Brucella melitensis ATCC 23457 MATE efflux family protein YP_002732115.1 368365 D 546272 CDS YP_002732116.1 225851883 7677511 complement(369826..370380) 1 NC_012441.1 invasion associated locus B family protein 370380 7677511 BMEA_A0376 Brucella melitensis ATCC 23457 invasion associated locus B family protein YP_002732116.1 369826 R 546272 CDS YP_002732117.1 225851884 7677512 370589..371962 1 NC_012441.1 integral membrane sensor signal transduction histidine kinase 371962 7677512 BMEA_A0377 Brucella melitensis ATCC 23457 integral membrane sensor signal transduction histidine kinase YP_002732117.1 370589 D 546272 CDS YP_002732118.1 225851885 7677513 371959..372600 1 NC_012441.1 LuxR family two component transcriptional regulator 372600 7677513 BMEA_A0378 Brucella melitensis ATCC 23457 LuxR family two component transcriptional regulator YP_002732118.1 371959 D 546272 CDS YP_002732119.1 225851886 7677514 372751..372861 1 NC_012441.1 hypothetical protein 372861 7677514 BMEA_A0379 Brucella melitensis ATCC 23457 hypothetical protein YP_002732119.1 372751 D 546272 CDS YP_002732120.1 225851887 7677515 372888..373436 1 NC_012441.1 hypothetical protein 373436 7677515 BMEA_A0380 Brucella melitensis ATCC 23457 hypothetical protein YP_002732120.1 372888 D 546272 CDS YP_002732121.1 225851888 7677516 373448..375016 1 NC_012441.1 TRAP C4-dicarboxylate transport system permease DctM 375016 7677516 BMEA_A0381 Brucella melitensis ATCC 23457 TRAP C4-dicarboxylate transport system permease DctM YP_002732121.1 373448 D 546272 CDS YP_002732122.1 225851889 7677517 375078..376187 1 NC_012441.1 RAP dicarboxylate transporter subunit DctP 376187 7677517 BMEA_A0382 Brucella melitensis ATCC 23457 RAP dicarboxylate transporter subunit DctP YP_002732122.1 375078 D 546272 CDS YP_002732123.1 225851890 7677518 complement(376270..377088) 1 NC_012441.1 hypothetical protein 377088 7677518 BMEA_A0383 Brucella melitensis ATCC 23457 hypothetical protein YP_002732123.1 376270 R 546272 CDS YP_002732124.1 225851891 7677519 complement(377101..378528) 1 NC_012441.1 urate catabolism protein 378528 7677519 BMEA_A0384 Brucella melitensis ATCC 23457 urate catabolism protein YP_002732124.1 377101 R 546272 CDS YP_002732125.1 225851892 7677520 378795..379070 1 NC_012441.1 hypothetical protein 379070 7677520 BMEA_A0385 Brucella melitensis ATCC 23457 hypothetical protein YP_002732125.1 378795 D 546272 CDS YP_002732126.1 225851893 7677521 379076..380551 1 NC_012441.1 xanthine dehydrogenase small subunit 380551 xdhA 7677521 xdhA Brucella melitensis ATCC 23457 xanthine dehydrogenase small subunit YP_002732126.1 379076 D 546272 CDS YP_002732127.1 225851894 7677522 380564..382909 1 NC_012441.1 xanthine dehydrogenase molybdopterin binding subunit 382909 xdhB 7677522 xdhB Brucella melitensis ATCC 23457 xanthine dehydrogenase molybdopterin binding subunit YP_002732127.1 380564 D 546272 CDS YP_002732128.1 225851895 7677523 382914..383786 1 NC_012441.1 xanthine dehydrogenase accessory protein XdhC 383786 xdhC 7677523 xdhC Brucella melitensis ATCC 23457 xanthine dehydrogenase accessory protein XdhC YP_002732128.1 382914 D 546272 CDS YP_002732129.1 225851896 7677524 complement(383867..384769) 1 NC_012441.1 LysR family transcriptional regulator 384769 7677524 BMEA_A0389 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002732129.1 383867 R 546272 CDS YP_002732130.1 225851897 7677525 384950..386203 1 NC_012441.1 hypothetical protein 386203 7677525 BMEA_A0390 Brucella melitensis ATCC 23457 hypothetical protein YP_002732130.1 384950 D 546272 CDS YP_002732131.1 225851898 7677526 386200..387504 1 NC_012441.1 Catalyzes the deamination of guanine; guanine deaminase 387504 guaD 7677526 guaD Brucella melitensis ATCC 23457 guanine deaminase YP_002732131.1 386200 D 546272 CDS YP_002732132.1 225851899 7677527 387584..388870 1 NC_012441.1 hydroxypyruvate reductase 388870 7677527 BMEA_A0392 Brucella melitensis ATCC 23457 hydroxypyruvate reductase YP_002732132.1 387584 D 546272 CDS YP_002732133.1 225851900 7677528 complement(388851..389009) 1 NC_012441.1 cbb3-type cytochrome maturation protein 389009 ccoS 7677528 ccoS Brucella melitensis ATCC 23457 cbb3-type cytochrome maturation protein YP_002732133.1 388851 R 546272 CDS YP_002732134.1 225851901 7677529 complement(389006..391264) 1 NC_012441.1 heavy metal translocating P-type ATPase 391264 7677529 BMEA_A0394 Brucella melitensis ATCC 23457 heavy metal translocating P-type ATPase YP_002732134.1 389006 R 546272 CDS YP_002732135.1 225851902 7677530 complement(391261..391758) 1 NC_012441.1 FixH family protein 391758 7677530 BMEA_A0395 Brucella melitensis ATCC 23457 FixH family protein YP_002732135.1 391261 R 546272 CDS YP_002732136.1 225851903 7677531 complement(391758..393308) 1 NC_012441.1 cytochrome c oxidase accessory protein CcoG 393308 ccoG 7677531 ccoG Brucella melitensis ATCC 23457 cytochrome c oxidase accessory protein CcoG YP_002732136.1 391758 R 546272 CDS YP_002732137.1 225851904 7677532 complement(393476..394339) 1 NC_012441.1 cbb3-type cytochrome c oxidase subunit III 394339 ccoP 7677532 ccoP Brucella melitensis ATCC 23457 cbb3-type cytochrome c oxidase subunit III YP_002732137.1 393476 R 546272 CDS YP_002732138.1 225851905 7677533 complement(394332..394490) 1 NC_012441.1 cbb3-type cytochrome oxidase subunit 394490 7677533 BMEA_A0398 Brucella melitensis ATCC 23457 cbb3-type cytochrome oxidase subunit YP_002732138.1 394332 R 546272 CDS YP_002732139.1 225851906 7677534 complement(394505..395236) 1 NC_012441.1 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 395236 ccoO 7677534 ccoO Brucella melitensis ATCC 23457 cbb3-type cytochrome c oxidase subunit II YP_002732139.1 394505 R 546272 CDS YP_002732140.1 225851907 7677535 complement(395251..396876) 1 NC_012441.1 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 396876 ccoN 7677535 ccoN Brucella melitensis ATCC 23457 cbb3-type cytochrome c oxidase subunit I YP_002732140.1 395251 R 546272 CDS YP_002732141.1 225851908 7677536 complement(397094..397552) 1 NC_012441.1 ferric uptake regulation protein 397552 7677536 BMEA_A0401 Brucella melitensis ATCC 23457 ferric uptake regulation protein YP_002732141.1 397094 R 546272 CDS YP_002732142.1 225851909 7677537 397551..397871 1 NC_012441.1 hypothetical protein 397871 7677537 BMEA_A0402 Brucella melitensis ATCC 23457 hypothetical protein YP_002732142.1 397551 D 546272 CDS YP_002732143.1 225851910 7677538 397983..398597 1 NC_012441.1 DSBA oxidoreductase 398597 7677538 BMEA_A0403 Brucella melitensis ATCC 23457 DSBA oxidoreductase YP_002732143.1 397983 D 546272 CDS YP_002732144.1 225851911 7677540 400289..401374 1 NC_012441.1 methylated-DNA--protein-cysteine methyltransferase 401374 7677540 BMEA_A0405 Brucella melitensis ATCC 23457 methylated-DNA--protein-cysteine methyltransferase YP_002732144.1 400289 D 546272 CDS YP_002732145.1 225851912 7677541 401556..401906 1 NC_012441.1 hypothetical protein 401906 7677541 BMEA_A0406 Brucella melitensis ATCC 23457 hypothetical protein YP_002732145.1 401556 D 546272 CDS YP_002732146.1 225851913 7677542 402243..403286 1 NC_012441.1 hypothetical protein 403286 7677542 BMEA_A0407 Brucella melitensis ATCC 23457 hypothetical protein YP_002732146.1 402243 D 546272 CDS YP_002732147.1 225851914 7677543 403436..404620 1 NC_012441.1 hypothetical protein 404620 7677543 BMEA_A0408 Brucella melitensis ATCC 23457 hypothetical protein YP_002732147.1 403436 D 546272 CDS YP_002732148.1 225851915 7677544 404842..406203 1 NC_012441.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 406203 7677544 BMEA_A0409 Brucella melitensis ATCC 23457 transporter YP_002732148.1 404842 D 546272 CDS YP_002732149.1 225851916 7677545 complement(406127..407125) 1 NC_012441.1 polysaccharide deacetylase 407125 7677545 BMEA_A0410 Brucella melitensis ATCC 23457 polysaccharide deacetylase YP_002732149.1 406127 R 546272 CDS YP_002732150.1 225851917 7677546 407371..408042 1 NC_012441.1 hypothetical protein 408042 7677546 BMEA_A0411 Brucella melitensis ATCC 23457 hypothetical protein YP_002732150.1 407371 D 546272 CDS YP_002732151.1 225851918 7677547 408064..409515 1 NC_012441.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 409515 7677547 BMEA_A0412 Brucella melitensis ATCC 23457 GTP-binding protein EngA YP_002732151.1 408064 D 546272 CDS YP_002732152.1 225851919 7677548 409674..410990 1 NC_012441.1 Hsp70 family protein 410990 7677548 BMEA_A0413 Brucella melitensis ATCC 23457 Hsp70 family protein YP_002732152.1 409674 D 546272 CDS YP_002732153.1 225851920 7677549 411427..412716 1 NC_012441.1 cell wall hydrolase SleB 412716 7677549 BMEA_A0414 Brucella melitensis ATCC 23457 cell wall hydrolase SleB YP_002732153.1 411427 D 546272 CDS YP_002732154.1 225851921 7677550 412987..413385 1 NC_012441.1 hypothetical protein 413385 7677550 BMEA_A0415 Brucella melitensis ATCC 23457 hypothetical protein YP_002732154.1 412987 D 546272 CDS YP_002732155.1 225851922 7677551 413493..414242 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 414242 atpB 7677551 atpB Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit A YP_002732155.1 413493 D 546272 CDS YP_002732156.1 225851923 7677552 414310..414537 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 414537 7677552 BMEA_A0417 Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit C YP_002732156.1 414310 D 546272 CDS YP_002732157.1 225851924 7677553 414709..415335 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 415335 7677553 BMEA_A0418 Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit B' YP_002732157.1 414709 D 546272 CDS YP_002732158.1 225851925 7677554 415346..415825 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 415825 atpF 7677554 atpF Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit B YP_002732158.1 415346 D 546272 CDS YP_002732159.1 225851926 7677555 complement(415948..416610) 1 NC_012441.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 416610 7677555 BMEA_A0420 Brucella melitensis ATCC 23457 ribonuclease HII YP_002732159.1 415948 R 546272 CDS YP_002732160.1 225851927 7677556 complement(416787..417953) 1 NC_012441.1 radical SAM domain-containing protein 417953 7677556 BMEA_A0421 Brucella melitensis ATCC 23457 radical SAM domain-containing protein YP_002732160.1 416787 R 546272 CDS YP_002732161.1 225851928 7677557 418089..418595 1 NC_012441.1 hypothetical protein 418595 7677557 BMEA_A0422 Brucella melitensis ATCC 23457 hypothetical protein YP_002732161.1 418089 D 546272 CDS YP_002732162.1 225851929 7677558 complement(418675..418941) 1 NC_012441.1 hypothetical protein 418941 7677558 BMEA_A0423 Brucella melitensis ATCC 23457 hypothetical protein YP_002732162.1 418675 R 546272 CDS YP_002732163.1 225851930 7676282 complement(419013..419225) 1 NC_012441.1 hypothetical protein 419225 7676282 BMEA_A0424 Brucella melitensis ATCC 23457 hypothetical protein YP_002732163.1 419013 R 546272 CDS YP_002732164.1 225851931 7676283 complement(419300..420199) 1 NC_012441.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 420199 ispE 7676283 ispE Brucella melitensis ATCC 23457 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002732164.1 419300 R 546272 CDS YP_002732165.1 225851932 7676730 complement(420229..420450) 1 NC_012441.1 hypothetical protein 420450 7676730 BMEA_A0427 Brucella melitensis ATCC 23457 hypothetical protein YP_002732165.1 420229 R 546272 CDS YP_002732166.1 225851933 7676731 complement(420881..423172) 1 NC_012441.1 Na+/H+ antiporter NhaA 423172 nhaA 7676731 nhaA Brucella melitensis ATCC 23457 Na+/H+ antiporter NhaA YP_002732166.1 420881 R 546272 CDS YP_002732167.1 225851934 7676732 complement(423111..423326) 1 NC_012441.1 hypothetical protein 423326 7676732 BMEA_A0429 Brucella melitensis ATCC 23457 hypothetical protein YP_002732167.1 423111 R 546272 CDS YP_002732168.1 225851935 7676733 complement(423381..424163) 1 NC_012441.1 methyltransferase small 424163 7676733 BMEA_A0430 Brucella melitensis ATCC 23457 methyltransferase small YP_002732168.1 423381 R 546272 CDS YP_002732169.1 225851936 7676734 complement(424160..424387) 1 NC_012441.1 hypothetical protein 424387 7676734 BMEA_A0431 Brucella melitensis ATCC 23457 hypothetical protein YP_002732169.1 424160 R 546272 CDS YP_002732170.1 225851937 7676735 424650..425672 1 NC_012441.1 hypothetical protein 425672 7676735 BMEA_A0432 Brucella melitensis ATCC 23457 hypothetical protein YP_002732170.1 424650 D 546272 CDS YP_002732171.1 225851938 7676736 425976..427841 1 NC_012441.1 hypothetical protein 427841 7676736 BMEA_A0433 Brucella melitensis ATCC 23457 hypothetical protein YP_002732171.1 425976 D 546272 CDS YP_002732172.1 225851939 7676737 427993..428919 1 NC_012441.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 428919 glyQ 7676737 glyQ Brucella melitensis ATCC 23457 glycyl-tRNA synthetase subunit alpha YP_002732172.1 427993 D 546272 CDS YP_002732173.1 225851940 7676738 428925..431258 1 NC_012441.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 431258 glyS 7676738 glyS Brucella melitensis ATCC 23457 glycyl-tRNA synthetase subunit beta YP_002732173.1 428925 D 546272 CDS YP_002732174.1 225851941 7676739 431397..432368 1 NC_012441.1 Sua5/YciO/YrdC/YwlC family protein 432368 7676739 BMEA_A0436 Brucella melitensis ATCC 23457 Sua5/YciO/YrdC/YwlC family protein YP_002732174.1 431397 D 546272 CDS YP_002732175.1 225851942 7676740 432394..433806 1 NC_012441.1 hypothetical protein 433806 7676740 BMEA_A0437 Brucella melitensis ATCC 23457 hypothetical protein YP_002732175.1 432394 D 546272 CDS YP_002732176.1 225851943 7676741 complement(433844..434161) 1 NC_012441.1 plasmid stabilization system 434161 7676741 BMEA_A0438 Brucella melitensis ATCC 23457 plasmid stabilization system YP_002732176.1 433844 R 546272 CDS YP_002732177.1 225851944 7676742 complement(434158..434418) 1 NC_012441.1 CopG-like DNA-binding protein 434418 7676742 BMEA_A0439 Brucella melitensis ATCC 23457 CopG-like DNA-binding protein YP_002732177.1 434158 R 546272 CDS YP_002732178.1 225851945 7676743 complement(434527..434739) 1 NC_012441.1 hypothetical protein 434739 7676743 BMEA_A0440 Brucella melitensis ATCC 23457 hypothetical protein YP_002732178.1 434527 R 546272 CDS YP_002732179.1 225851946 7676744 434729..435295 1 NC_012441.1 hypothetical protein 435295 7676744 BMEA_A0441 Brucella melitensis ATCC 23457 hypothetical protein YP_002732179.1 434729 D 546272 CDS YP_002732180.1 225851947 7676745 complement(435438..436190) 1 NC_012441.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 436190 7676745 BMEA_A0442 Brucella melitensis ATCC 23457 enoyl-CoA hydratase YP_002732180.1 435438 R 546272 CDS YP_002732181.1 225851948 7676746 complement(436193..437971) 1 NC_012441.1 acyl-CoA dehydrogenase domain-containing protein 437971 7676746 BMEA_A0443 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase domain-containing protein YP_002732181.1 436193 R 546272 CDS YP_002732182.1 225851949 7676747 438289..439434 1 NC_012441.1 diguanylate cyclase GGDEF domain-containing protein 439434 7676747 BMEA_A0444 Brucella melitensis ATCC 23457 diguanylate cyclase GGDEF domain-containing protein YP_002732182.1 438289 D 546272 CDS YP_002732183.1 225851950 7676748 complement(439452..440735) 1 NC_012441.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 440735 purD 7676748 purD Brucella melitensis ATCC 23457 phosphoribosylamine--glycine ligase YP_002732183.1 439452 R 546272 CDS YP_002732184.1 225851951 7676749 440880..441881 1 NC_012441.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 441881 ubiA 7676749 ubiA Brucella melitensis ATCC 23457 4-hydroxybenzoate polyprenyltransferase YP_002732184.1 440880 D 546272 CDS YP_002732185.1 225851952 7676750 complement(441921..442532) 1 NC_012441.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 442532 pdxH 7676750 pdxH Brucella melitensis ATCC 23457 pyridoxamine 5'-phosphate oxidase YP_002732185.1 441921 R 546272 CDS YP_002732186.1 225851953 7676752 443420..444361 1 NC_012441.1 chaperone protein DnaJ 444361 7676752 BMEA_A0449 Brucella melitensis ATCC 23457 chaperone protein DnaJ YP_002732186.1 443420 D 546272 CDS YP_002732187.1 225851954 7676753 complement(444365..444472) 1 NC_012441.1 hypothetical protein 444472 7676753 BMEA_A0450 Brucella melitensis ATCC 23457 hypothetical protein YP_002732187.1 444365 R 546272 CDS YP_002732188.1 225851955 7676754 444505..445323 1 NC_012441.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 445323 7676754 BMEA_A0451 Brucella melitensis ATCC 23457 enoyl-(acyl carrier protein) reductase YP_002732188.1 444505 D 546272 CDS YP_002732189.1 225851956 7676755 445837..446028 1 NC_012441.1 phosphoglycerate mutase 446028 7676755 BMEA_A0452 Brucella melitensis ATCC 23457 phosphoglycerate mutase YP_002732189.1 445837 D 546272 CDS YP_002732190.1 225851957 7676756 446290..446499 1 NC_012441.1 ATP/GTP-binding domain-containing protein 446499 7676756 BMEA_A0454 Brucella melitensis ATCC 23457 ATP/GTP-binding domain-containing protein YP_002732190.1 446290 D 546272 CDS YP_002732191.1 225851958 7676757 complement(446597..446746) 1 NC_012441.1 hypothetical protein 446746 7676757 BMEA_A0455 Brucella melitensis ATCC 23457 hypothetical protein YP_002732191.1 446597 R 546272 CDS YP_002732192.1 225851959 7676758 446969..447181 1 NC_012441.1 hypothetical protein 447181 7676758 BMEA_A0456 Brucella melitensis ATCC 23457 hypothetical protein YP_002732192.1 446969 D 546272 CDS YP_002732193.1 225851960 7676759 447258..447935 1 NC_012441.1 hypothetical protein 447935 7676759 BMEA_A0457 Brucella melitensis ATCC 23457 hypothetical protein YP_002732193.1 447258 D 546272 CDS YP_002732194.1 225851961 7676760 447971..448105 1 NC_012441.1 hypothetical protein 448105 7676760 BMEA_A0458 Brucella melitensis ATCC 23457 hypothetical protein YP_002732194.1 447971 D 546272 CDS YP_002732195.1 225851962 7676761 complement(448080..448331) 1 NC_012441.1 hypothetical protein 448331 7676761 BMEA_A0459 Brucella melitensis ATCC 23457 hypothetical protein YP_002732195.1 448080 R 546272 CDS YP_002732196.1 225851963 7676762 448455..448556 1 NC_012441.1 hypothetical protein 448556 7676762 BMEA_A0460 Brucella melitensis ATCC 23457 hypothetical protein YP_002732196.1 448455 D 546272 CDS YP_002732197.1 225851964 7676763 448605..449699 1 NC_012441.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 449699 aroC 7676763 aroC Brucella melitensis ATCC 23457 chorismate synthase YP_002732197.1 448605 D 546272 CDS YP_002732198.1 225851965 7676764 449835..450950 1 NC_012441.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 450950 ribB 7676764 ribB Brucella melitensis ATCC 23457 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002732198.1 449835 D 546272 CDS YP_002732199.1 225851966 7676765 451166..452116 1 NC_012441.1 histone deacetylase superfamily protein 452116 7676765 BMEA_A0463 Brucella melitensis ATCC 23457 histone deacetylase superfamily protein YP_002732199.1 451166 D 546272 CDS YP_002732200.1 225851967 7676766 452121..452375 1 NC_012441.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 452375 xseB 7676766 xseB Brucella melitensis ATCC 23457 exodeoxyribonuclease VII small subunit YP_002732200.1 452121 D 546272 CDS YP_002732201.1 225851968 7676767 complement(452382..452900) 1 NC_012441.1 hypothetical protein 452900 7676767 BMEA_A0465 Brucella melitensis ATCC 23457 hypothetical protein YP_002732201.1 452382 R 546272 CDS YP_002732202.1 225851969 7676768 complement(453142..453402) 1 NC_012441.1 transglycosylase-associated protein 453402 7676768 BMEA_A0466 Brucella melitensis ATCC 23457 transglycosylase-associated protein YP_002732202.1 453142 R 546272 CDS YP_002732203.1 225851970 7676769 453565..454116 1 NC_012441.1 hypothetical protein 454116 7676769 BMEA_A0467 Brucella melitensis ATCC 23457 hypothetical protein YP_002732203.1 453565 D 546272 CDS YP_002732204.1 225851971 7676770 454320..455192 1 NC_012441.1 Pirin domain-containing protein 455192 7676770 BMEA_A0468 Brucella melitensis ATCC 23457 Pirin domain-containing protein YP_002732204.1 454320 D 546272 CDS YP_002732205.1 225851972 7676771 455335..457266 1 NC_012441.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 457266 dxs 7676771 dxs Brucella melitensis ATCC 23457 1-deoxy-D-xylulose-5-phosphate synthase YP_002732205.1 455335 D 546272 CDS YP_002732206.1 225851973 7676772 457272..458033 1 NC_012441.1 hemolysin A 458033 7676772 BMEA_A0470 Brucella melitensis ATCC 23457 hemolysin A YP_002732206.1 457272 D 546272 CDS YP_002732207.1 225851974 7676773 458030..459277 1 NC_012441.1 tRNA (Uracil-5-)-methyltransferase 459277 7676773 BMEA_A0471 Brucella melitensis ATCC 23457 tRNA (Uracil-5-)-methyltransferase YP_002732207.1 458030 D 546272 CDS YP_002732208.1 225851975 7676774 complement(459429..460031) 1 NC_012441.1 hypothetical protein 460031 7676774 BMEA_A0472 Brucella melitensis ATCC 23457 hypothetical protein YP_002732208.1 459429 R 546272 CDS YP_002732209.1 225851976 7676775 460161..460526 1 NC_012441.1 hypothetical protein 460526 7676775 BMEA_A0473 Brucella melitensis ATCC 23457 hypothetical protein YP_002732209.1 460161 D 546272 CDS YP_002732210.1 225851977 7676776 460713..461927 1 NC_012441.1 peptidoglycan-binding LysM 461927 7676776 BMEA_A0474 Brucella melitensis ATCC 23457 peptidoglycan-binding LysM YP_002732210.1 460713 D 546272 CDS YP_002732211.1 225851978 7676777 462130..464016 1 NC_012441.1 ABC transporter 464016 7676777 BMEA_A0475 Brucella melitensis ATCC 23457 ABC transporter YP_002732211.1 462130 D 546272 CDS YP_002732212.1 225851979 7676778 464121..464819 1 NC_012441.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 464819 7676778 BMEA_A0476 Brucella melitensis ATCC 23457 phosphatidylserine decarboxylase YP_002732212.1 464121 D 546272 CDS YP_002732213.1 225851980 7676779 464824..465660 1 NC_012441.1 CDP-diacylglycerol--serine O-phosphatidyltransferase 465660 pssA 7676779 pssA Brucella melitensis ATCC 23457 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_002732213.1 464824 D 546272 CDS YP_002732214.1 225851981 7676780 complement(465745..466485) 1 NC_012441.1 short-chain dehydrogenase/reductase SDR 466485 7676780 BMEA_A0479 Brucella melitensis ATCC 23457 short-chain dehydrogenase/reductase SDR YP_002732214.1 465745 R 546272 CDS YP_002732215.1 225851982 7676781 complement(466554..468011) 1 NC_012441.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 468011 purF 7676781 purF Brucella melitensis ATCC 23457 amidophosphoribosyltransferase YP_002732215.1 466554 R 546272 CDS YP_002732216.1 225851983 7676782 468033..468230 1 NC_012441.1 hypothetical protein 468230 7676782 BMEA_A0481 Brucella melitensis ATCC 23457 hypothetical protein YP_002732216.1 468033 D 546272 CDS YP_002732217.1 225851984 7676783 complement(468326..468904) 1 NC_012441.1 colicin V production protein 468904 7676783 BMEA_A0482 Brucella melitensis ATCC 23457 colicin V production protein YP_002732217.1 468326 R 546272 CDS YP_002732218.1 225851985 7676784 complement(469030..470433) 1 NC_012441.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 470433 radA 7676784 radA Brucella melitensis ATCC 23457 DNA repair protein RadA YP_002732218.1 469030 R 546272 CDS YP_002732219.1 225851986 7676785 complement(470461..471966) 1 NC_012441.1 unwinds double stranded DNA; replicative DNA helicase 471966 dnaB 7676785 dnaB Brucella melitensis ATCC 23457 replicative DNA helicase YP_002732219.1 470461 R 546272 CDS YP_002732220.1 225851987 7676786 complement(472165..473445) 1 NC_012441.1 cyclopropane-fatty-acyl-phospholipid synthase 473445 7676786 BMEA_A0485 Brucella melitensis ATCC 23457 cyclopropane-fatty-acyl-phospholipid synthase YP_002732220.1 472165 R 546272 CDS YP_002732221.1 225851988 7676787 complement(473819..474388) 1 NC_012441.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 474388 rplI 7676787 rplI Brucella melitensis ATCC 23457 50S ribosomal protein L9 YP_002732221.1 473819 R 546272 CDS YP_002732222.1 225851989 7676788 complement(474418..475389) 1 NC_012441.1 hypothetical protein 475389 7676788 BMEA_A0487 Brucella melitensis ATCC 23457 hypothetical protein YP_002732222.1 474418 R 546272 CDS YP_002732223.1 225851990 7676789 complement(475540..475788) 1 NC_012441.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 475788 rpsR 7676789 rpsR Brucella melitensis ATCC 23457 30S ribosomal protein S18 YP_002732223.1 475540 R 546272 CDS YP_002732224.1 225851991 7676790 complement(475791..476237) 1 NC_012441.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 476237 rpsF 7676790 rpsF Brucella melitensis ATCC 23457 30S ribosomal protein S6 YP_002732224.1 475791 R 546272 CDS YP_002732225.1 225851992 7676791 complement(476262..476621) 1 NC_012441.1 hypothetical protein 476621 7676791 BMEA_A0491 Brucella melitensis ATCC 23457 hypothetical protein YP_002732225.1 476262 R 546272 CDS YP_002732226.1 225851993 7676792 476643..477587 1 NC_012441.1 malonyl CoA-acyl carrier protein transacylase 477587 fabD 7676792 fabD Brucella melitensis ATCC 23457 malonyl CoA-acyl carrier protein transacylase YP_002732226.1 476643 D 546272 CDS YP_002732227.1 225851994 7676793 477657..478394 1 NC_012441.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 478394 fabG 7676793 fabG Brucella melitensis ATCC 23457 3-ketoacyl-ACP reductase YP_002732227.1 477657 D 546272 CDS YP_002732228.1 225851995 7676794 complement(478596..478967) 1 NC_012441.1 acyl carrier protein 478967 7676794 BMEA_A0494 Brucella melitensis ATCC 23457 acyl carrier protein YP_002732228.1 478596 R 546272 CDS YP_002732229.1 225851996 7676795 478668..478904 1 NC_012441.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 478904 acpP 7676795 acpP Brucella melitensis ATCC 23457 acyl carrier protein YP_002732229.1 478668 D 546272 CDS YP_002732230.1 225851997 7676796 478908..479171 1 NC_012441.1 hypothetical protein 479171 7676796 BMEA_A0496 Brucella melitensis ATCC 23457 hypothetical protein YP_002732230.1 478908 D 546272 CDS YP_002732231.1 225851998 7676797 479228..480490 1 NC_012441.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 480490 fabF 7676797 fabF Brucella melitensis ATCC 23457 3-oxoacyl-(acyl carrier protein) synthase II YP_002732231.1 479228 D 546272 CDS YP_002732232.1 225851999 7676798 480715..481953 1 NC_012441.1 hypothetical protein 481953 7676798 BMEA_A0498 Brucella melitensis ATCC 23457 hypothetical protein YP_002732232.1 480715 D 546272 CDS YP_002732233.1 225852000 7676800 483045..483707 1 NC_012441.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 483707 gmk 7676800 gmk Brucella melitensis ATCC 23457 guanylate kinase YP_002732233.1 483045 D 546272 CDS YP_002732234.1 225852001 7676801 complement(483734..485146) 1 NC_012441.1 peptidase U62 485146 7676801 BMEA_A0501 Brucella melitensis ATCC 23457 peptidase U62 YP_002732234.1 483734 R 546272 CDS YP_002732235.1 225852002 7676802 complement(485287..485913) 1 NC_012441.1 invasion associated locus B family protein 485913 7676802 BMEA_A0502 Brucella melitensis ATCC 23457 invasion associated locus B family protein YP_002732235.1 485287 R 546272 CDS YP_002732236.1 225852003 7676803 486347..487201 1 NC_012441.1 cytochrome c oxidase subunit II 487201 coxB 7676803 coxB Brucella melitensis ATCC 23457 cytochrome c oxidase subunit II YP_002732236.1 486347 D 546272 CDS YP_002732237.1 225852004 7676804 487339..488997 1 NC_012441.1 cytochrome c oxidase subunit I 488997 ctaD 7676804 ctaD Brucella melitensis ATCC 23457 cytochrome c oxidase subunit I YP_002732237.1 487339 D 546272 CDS YP_002732238.1 225852005 7676805 489225..490172 1 NC_012441.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 490172 cyoE 7676805 cyoE Brucella melitensis ATCC 23457 protoheme IX farnesyltransferase YP_002732238.1 489225 D 546272 CDS YP_002732239.1 225852006 7676806 490172..490357 1 NC_012441.1 hypothetical protein 490357 7676806 BMEA_A0506 Brucella melitensis ATCC 23457 hypothetical protein YP_002732239.1 490172 D 546272 CDS YP_002732240.1 225852007 7676807 490377..490982 1 NC_012441.1 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 490982 7676807 BMEA_A0507 Brucella melitensis ATCC 23457 cytochrome C oxidase assembly protein YP_002732240.1 490377 D 546272 CDS YP_002732241.1 225852008 7676808 491191..492069 1 NC_012441.1 cytochrome c oxidase subunit 3 492069 7676808 BMEA_A0508 Brucella melitensis ATCC 23457 cytochrome c oxidase subunit 3 YP_002732241.1 491191 D 546272 CDS YP_002732242.1 225852009 7676809 492183..492566 1 NC_012441.1 hypothetical protein 492566 7676809 BMEA_A0509 Brucella melitensis ATCC 23457 hypothetical protein YP_002732242.1 492183 D 546272 CDS YP_002732243.1 225852010 7676810 492563..493312 1 NC_012441.1 surfeit locus protein 1 493312 7676810 BMEA_A0510 Brucella melitensis ATCC 23457 surfeit locus protein 1 YP_002732243.1 492563 D 546272 CDS YP_002732244.1 225852011 7676811 493343..494461 1 NC_012441.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 494461 ispH 7676811 ispH Brucella melitensis ATCC 23457 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002732244.1 493343 D 546272 CDS YP_002732245.1 225852012 7676812 494467..495447 1 NC_012441.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 495447 thrB 7676812 thrB Brucella melitensis ATCC 23457 homoserine kinase YP_002732245.1 494467 D 546272 CDS YP_002732246.1 225852013 7676813 495444..495908 1 NC_012441.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 495908 7676813 BMEA_A0513 Brucella melitensis ATCC 23457 ribonuclease H YP_002732246.1 495444 D 546272 CDS YP_002732247.1 225852014 7676814 complement(495938..496423) 1 NC_012441.1 redoxin domain-containing protein 496423 7676814 BMEA_A0514 Brucella melitensis ATCC 23457 redoxin domain-containing protein YP_002732247.1 495938 R 546272 CDS YP_002732248.1 225852015 7676815 complement(496603..497403) 1 NC_012441.1 hypothetical protein 497403 7676815 BMEA_A0515 Brucella melitensis ATCC 23457 hypothetical protein YP_002732248.1 496603 R 546272 CDS YP_002732249.1 225852016 7676816 497538..498140 1 NC_012441.1 hypothetical protein 498140 7676816 BMEA_A0516 Brucella melitensis ATCC 23457 hypothetical protein YP_002732249.1 497538 D 546272 CDS YP_002732250.1 225852017 7676817 complement(498246..501140) 1 NC_012441.1 diguanylate cyclase 501140 7676817 BMEA_A0517 Brucella melitensis ATCC 23457 diguanylate cyclase YP_002732250.1 498246 R 546272 CDS YP_002732251.1 225852018 7676818 complement(501137..501757) 1 NC_012441.1 N-acetyltransferase GCN5 501757 7676818 BMEA_A0518 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002732251.1 501137 R 546272 CDS YP_002732252.1 225852019 7676819 complement(501928..503220) 1 NC_012441.1 processing protease 503220 7676819 BMEA_A0519 Brucella melitensis ATCC 23457 processing protease YP_002732252.1 501928 R 546272 CDS YP_002732253.1 225852020 7676820 complement(503274..504665) 1 NC_012441.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 504665 thrC 7676820 thrC Brucella melitensis ATCC 23457 threonine synthase YP_002732253.1 503274 R 546272 CDS YP_002732254.1 225852021 7676821 505026..505604 1 NC_012441.1 lipoprotein 505604 7676821 BMEA_A0521 Brucella melitensis ATCC 23457 lipoprotein YP_002732254.1 505026 D 546272 CDS YP_002732255.1 225852022 7676822 505918..507552 1 NC_012441.1 hypothetical protein 507552 7676822 BMEA_A0522 Brucella melitensis ATCC 23457 hypothetical protein YP_002732255.1 505918 D 546272 CDS YP_002732256.1 225852023 7676823 507681..507866 1 NC_012441.1 hypothetical protein 507866 7676823 BMEA_A0524 Brucella melitensis ATCC 23457 hypothetical protein YP_002732256.1 507681 D 546272 CDS YP_002732257.1 225852024 7676824 complement(507908..508594) 1 NC_012441.1 HAD-superfamily hydrolase 508594 7676824 BMEA_A0525 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002732257.1 507908 R 546272 CDS YP_002732258.1 225852025 7676825 complement(508742..510280) 1 NC_012441.1 chloride channel core protein 510280 7676825 BMEA_A0526 Brucella melitensis ATCC 23457 chloride channel core protein YP_002732258.1 508742 R 546272 CDS YP_002732259.1 225852026 7676826 complement(510259..510399) 1 NC_012441.1 hypothetical protein 510399 7676826 BMEA_A0527 Brucella melitensis ATCC 23457 hypothetical protein YP_002732259.1 510259 R 546272 CDS YP_002732260.1 225852027 7676827 510593..511726 1 NC_012441.1 modification methylase HinfI 511726 7676827 BMEA_A0528 Brucella melitensis ATCC 23457 modification methylase HinfI YP_002732260.1 510593 D 546272 CDS YP_002732261.1 225852028 7676828 complement(511809..512426) 1 NC_012441.1 HAD-superfamily hydrolase 512426 7676828 BMEA_A0529 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002732261.1 511809 R 546272 CDS YP_002732262.1 225852029 7676829 complement(512423..513499) 1 NC_012441.1 A/G-specific adenine glycosylase 513499 mutY 7676829 mutY Brucella melitensis ATCC 23457 A/G-specific adenine glycosylase YP_002732262.1 512423 R 546272 CDS YP_002732263.1 225852030 7676830 513773..514300 1 NC_012441.1 hypothetical protein 514300 7676830 BMEA_A0531 Brucella melitensis ATCC 23457 hypothetical protein YP_002732263.1 513773 D 546272 CDS YP_002732264.1 225852031 7676831 514318..514491 1 NC_012441.1 hypothetical protein 514491 7676831 BMEA_A0532 Brucella melitensis ATCC 23457 hypothetical protein YP_002732264.1 514318 D 546272 CDS YP_002732265.1 225852032 7676832 514538..515191 1 NC_012441.1 DSBA oxidoreductase 515191 7676832 BMEA_A0533 Brucella melitensis ATCC 23457 DSBA oxidoreductase YP_002732265.1 514538 D 546272 CDS YP_002732266.1 225852033 7676833 515270..518728 1 NC_012441.1 chromosome segregation protein SMC 518728 smc 7676833 smc Brucella melitensis ATCC 23457 chromosome segregation protein SMC YP_002732266.1 515270 D 546272 CDS YP_002732267.1 225852034 7676834 518751..519644 1 NC_012441.1 cation diffusion facilitator family transporter 519644 7676834 BMEA_A0535 Brucella melitensis ATCC 23457 cation diffusion facilitator family transporter YP_002732267.1 518751 D 546272 CDS YP_002732268.1 225852035 7676835 complement(519754..520119) 1 NC_012441.1 hypothetical protein 520119 7676835 BMEA_A0536 Brucella melitensis ATCC 23457 hypothetical protein YP_002732268.1 519754 R 546272 CDS YP_002732269.1 225852036 7676836 520359..523022 1 NC_012441.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 523022 ppdK 7676836 ppdK Brucella melitensis ATCC 23457 pyruvate phosphate dikinase YP_002732269.1 520359 D 546272 CDS YP_002732270.1 225852037 7676837 523236..524054 1 NC_012441.1 polysaccharide deacetylase 524054 7676837 BMEA_A0538 Brucella melitensis ATCC 23457 polysaccharide deacetylase YP_002732270.1 523236 D 546272 CDS YP_002732271.1 225852038 7676838 complement(524257..524403) 1 NC_012441.1 hypothetical protein 524403 7676838 BMEA_A0539 Brucella melitensis ATCC 23457 hypothetical protein YP_002732271.1 524257 R 546272 CDS YP_002732272.1 225852039 7676839 525015..525803 1 NC_012441.1 hypothetical protein 525803 7676839 BMEA_A0540 Brucella melitensis ATCC 23457 hypothetical protein YP_002732272.1 525015 D 546272 CDS YP_002732273.1 225852040 7676840 complement(525804..526709) 1 NC_012441.1 beta-lactamase domain-containing protein 526709 7676840 BMEA_A0541 Brucella melitensis ATCC 23457 beta-lactamase domain-containing protein YP_002732273.1 525804 R 546272 CDS YP_002732274.1 225852041 7676841 526910..527509 1 NC_012441.1 protein BioY 527509 7676841 BMEA_A0542 Brucella melitensis ATCC 23457 protein BioY YP_002732274.1 526910 D 546272 CDS YP_002732275.1 225852042 7676842 527645..528154 1 NC_012441.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 528154 7676842 BMEA_A0543 Brucella melitensis ATCC 23457 ureidoglycolate hydrolase YP_002732275.1 527645 D 546272 CDS YP_002732276.1 225852043 7676843 528166..528522 1 NC_012441.1 hydroxyisourate hydrolase 528522 pucM 7676843 pucM Brucella melitensis ATCC 23457 hydroxyisourate hydrolase YP_002732276.1 528166 D 546272 CDS YP_002732277.1 225852044 7676844 528593..529429 1 NC_012441.1 hypothetical protein 529429 7676844 BMEA_A0545 Brucella melitensis ATCC 23457 hypothetical protein YP_002732277.1 528593 D 546272 CDS YP_002732278.1 225852045 7676845 529966..531834 1 NC_012441.1 polysaccharide biosynthesis protein CapD 531834 7676845 BMEA_A0546 Brucella melitensis ATCC 23457 polysaccharide biosynthesis protein CapD YP_002732278.1 529966 D 546272 CDS YP_002732279.1 225852046 7676846 complement(531821..532828) 1 NC_012441.1 family 4 glycosyl transferase 532828 7676846 BMEA_A0547 Brucella melitensis ATCC 23457 family 4 glycosyl transferase YP_002732279.1 531821 R 546272 CDS YP_002732280.1 225852047 7676848 533487..534305 1 NC_012441.1 transposase and inactivated derivatives-like protein 534305 7676848 BMEA_A0549 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002732280.1 533487 D 546272 CDS YP_002732281.1 225852048 7676849 534037..534624 1 NC_012441.1 insertion sequence transposase protein 534624 7676849 BMEA_A0550 Brucella melitensis ATCC 23457 insertion sequence transposase protein YP_002732281.1 534037 D 546272 CDS YP_002732282.1 225852049 7678309 534681..534980 1 NC_012441.1 insertion sequence transposase protein 534980 7678309 BMEA_A0551 Brucella melitensis ATCC 23457 insertion sequence transposase protein YP_002732282.1 534681 D 546272 CDS YP_002732283.1 225852050 7678310 535037..535267 1 NC_012441.1 transposase 535267 7678310 BMEA_A0552 Brucella melitensis ATCC 23457 transposase YP_002732283.1 535037 D 546272 CDS YP_002732284.1 225852051 7678311 535518..535643 1 NC_012441.1 transposase IS3/IS911 family protein 535643 7678311 BMEA_A0553 Brucella melitensis ATCC 23457 transposase IS3/IS911 family protein YP_002732284.1 535518 D 546272 CDS YP_002732285.1 225852052 7678312 535637..536359 1 NC_012441.1 Is511 transposase orfB 536359 7678312 BMEA_A0554 Brucella melitensis ATCC 23457 Is511 transposase orfB YP_002732285.1 535637 D 546272 CDS YP_002732286.1 225852053 7678313 complement(536695..537474) 1 NC_012441.1 bifunctional polymyxin resistance protein ArnA 537474 7678313 BMEA_A0555 Brucella melitensis ATCC 23457 bifunctional polymyxin resistance protein ArnA YP_002732286.1 536695 R 546272 CDS YP_002732287.1 225852054 7678314 complement(537501..538355) 1 NC_012441.1 WbcT protein 538355 7678314 BMEA_A0556 Brucella melitensis ATCC 23457 WbcT protein YP_002732287.1 537501 R 546272 CDS YP_002732288.1 225852055 7678315 complement(538352..539110) 1 NC_012441.1 O-antigen export system ATP-binding protein rfbB 539110 7678315 BMEA_A0557 Brucella melitensis ATCC 23457 O-antigen export system ATP-binding protein rfbB YP_002732288.1 538352 R 546272 CDS YP_002732289.1 225852056 7678316 complement(539107..539889) 1 NC_012441.1 O-antigen export system permease rfbD 539889 7678316 BMEA_A0558 Brucella melitensis ATCC 23457 O-antigen export system permease rfbD YP_002732289.1 539107 R 546272 CDS YP_002732290.1 225852057 7678317 complement(539904..541007) 1 NC_012441.1 L-glutamine:2-deoxy-scyllo-inosose aminotransferase 541007 7678317 BMEA_A0559 Brucella melitensis ATCC 23457 L-glutamine:2-deoxy-scyllo-inosose aminotransferase YP_002732290.1 539904 R 546272 CDS YP_002732291.1 225852058 7678318 complement(541015..542103) 1 NC_012441.1 GDP-mannose 4,6-dehydratase 542103 gmd 7678318 gmd Brucella melitensis ATCC 23457 GDP-mannose 4,6-dehydratase YP_002732291.1 541015 R 546272 CDS YP_002732292.1 225852059 7678319 542741..543049 1 NC_012441.1 ISBm1 transposase orfA 543049 7678319 BMEA_A0561 Brucella melitensis ATCC 23457 ISBm1 transposase orfA YP_002732292.1 542741 D 546272 CDS YP_002732293.1 225852060 7678320 542968..543342 1 NC_012441.1 transposase and inactivated derivatives-like protein 543342 7678320 BMEA_A0562 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002732293.1 542968 D 546272 CDS YP_002732294.1 225852061 7678322 544235..544567 1 NC_012441.1 transposase 544567 7678322 BMEA_A0564 Brucella melitensis ATCC 23457 transposase YP_002732294.1 544235 D 546272 CDS YP_002732295.1 225852062 7678323 544993..545232 1 NC_012441.1 transposase and inactivated derivatives-like protein 545232 7678323 BMEA_A0565 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002732295.1 544993 D 546272 CDS YP_002732296.1 225852063 7678324 545363..546481 1 NC_012441.1 mannosyltransferase 546481 7678324 BMEA_A0566 Brucella melitensis ATCC 23457 mannosyltransferase YP_002732296.1 545363 D 546272 CDS YP_002732297.1 225852064 7678325 546539..546907 1 NC_012441.1 transposase orfA IS5 family protein 546907 7678325 BMEA_A0567 Brucella melitensis ATCC 23457 transposase orfA IS5 family protein YP_002732297.1 546539 D 546272 CDS YP_002732298.1 225852065 7678326 547003..547344 1 NC_012441.1 transposase 547344 7678326 BMEA_A0568 Brucella melitensis ATCC 23457 transposase YP_002732298.1 547003 D 546272 CDS YP_002732299.1 225852066 7678328 complement(547808..547945) 1 NC_012441.1 Integrase, catalytic domain-containing protein 547945 7678328 BMEA_A0570 Brucella melitensis ATCC 23457 Integrase, catalytic domain-containing protein YP_002732299.1 547808 R 546272 CDS YP_002732300.1 225852067 7678329 548152..548580 1 NC_012441.1 ISBm1 transposase orfA 548580 7678329 BMEA_A0571 Brucella melitensis ATCC 23457 ISBm1 transposase orfA YP_002732300.1 548152 D 546272 CDS YP_002732301.1 225852068 7678330 548499..548915 1 NC_012441.1 transposase and inactivated derivatives-like protein 548915 7678330 BMEA_A0572 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002732301.1 548499 D 546272 CDS YP_002732302.1 225852069 7678331 549275..549574 1 NC_012441.1 hypothetical protein 549574 7678331 BMEA_A0573 Brucella melitensis ATCC 23457 hypothetical protein YP_002732302.1 549275 D 546272 CDS YP_002732303.1 225852070 7678332 549806..551095 1 NC_012441.1 phosphomannomutase 551095 7678332 BMEA_A0574 Brucella melitensis ATCC 23457 phosphomannomutase YP_002732303.1 549806 D 546272 CDS YP_002732304.1 225852071 7678333 551166..552590 1 NC_012441.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 552590 7678333 BMEA_A0575 Brucella melitensis ATCC 23457 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002732304.1 551166 D 546272 CDS YP_002732305.1 225852072 7678334 552623..553795 1 NC_012441.1 phosphomannose isomerase 553795 7678334 BMEA_A0576 Brucella melitensis ATCC 23457 phosphomannose isomerase YP_002732305.1 552623 D 546272 CDS YP_002732306.1 225852073 7678335 553878..554987 1 NC_012441.1 glycosyltransferase protein 554987 7678335 BMEA_A0577 Brucella melitensis ATCC 23457 glycosyltransferase protein YP_002732306.1 553878 D 546272 CDS YP_002732307.1 225852074 7678336 complement(555468..555647) 1 NC_012441.1 hypothetical protein 555647 7678336 BMEA_A0578 Brucella melitensis ATCC 23457 hypothetical protein YP_002732307.1 555468 R 546272 CDS YP_002732308.1 225852075 7678338 557233..558234 1 NC_012441.1 monosaccharide-transporting ATPase 558234 7678338 BMEA_A0580 Brucella melitensis ATCC 23457 monosaccharide-transporting ATPase YP_002732308.1 557233 D 546272 CDS YP_002732309.1 225852076 7678339 558313..559275 1 NC_012441.1 hypothetical protein 559275 7678339 BMEA_A0582 Brucella melitensis ATCC 23457 hypothetical protein YP_002732309.1 558313 D 546272 CDS YP_002732310.1 225852077 7678340 559333..560385 1 NC_012441.1 hypothetical protein 560385 7678340 BMEA_A0583 Brucella melitensis ATCC 23457 hypothetical protein YP_002732310.1 559333 D 546272 CDS YP_002732311.1 225852078 7678341 560393..561565 1 NC_012441.1 oxidoreductase domain-containing protein 561565 7678341 BMEA_A0584 Brucella melitensis ATCC 23457 oxidoreductase domain-containing protein YP_002732311.1 560393 D 546272 CDS YP_002732312.1 225852079 7678342 complement(561607..562914) 1 NC_012441.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 562914 xylA 7678342 xylA Brucella melitensis ATCC 23457 xylose isomerase YP_002732312.1 561607 R 546272 CDS YP_002732313.1 225852080 7678343 complement(562961..564412) 1 NC_012441.1 xylulokinase 564412 xylB 7678343 xylB Brucella melitensis ATCC 23457 xylulokinase YP_002732313.1 562961 R 546272 CDS YP_002732314.1 225852081 7678344 complement(564445..565476) 1 NC_012441.1 HTH-type transcriptional regulator DegA 565476 7678344 BMEA_A0587 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator DegA YP_002732314.1 564445 R 546272 CDS YP_002732315.1 225852082 7678346 complement(567272..568735) 1 NC_012441.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 568735 betB 7678346 betB Brucella melitensis ATCC 23457 betaine aldehyde dehydrogenase YP_002732315.1 567272 R 546272 CDS YP_002732316.1 225852083 7678348 complement(570572..571168) 1 NC_012441.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 571168 betI 7678348 betI Brucella melitensis ATCC 23457 transcriptional regulator BetI YP_002732316.1 570572 R 546272 CDS YP_002732317.1 225852084 7678349 571359..572381 1 NC_012441.1 L-asparaginase II protein 572381 7678349 BMEA_A0592 Brucella melitensis ATCC 23457 L-asparaginase II protein YP_002732317.1 571359 D 546272 CDS YP_002732318.1 225852085 7678350 572426..572896 1 NC_012441.1 Transcription elongation factor greA 572896 7678350 BMEA_A0593 Brucella melitensis ATCC 23457 Transcription elongation factor greA YP_002732318.1 572426 D 546272 CDS YP_002732319.1 225852086 7678351 complement(572893..573282) 1 NC_012441.1 death-on-curing family protein 573282 7678351 BMEA_A0594 Brucella melitensis ATCC 23457 death-on-curing family protein YP_002732319.1 572893 R 546272 CDS YP_002732320.1 225852087 7678352 complement(573279..573509) 1 NC_012441.1 addiction module antidote 573509 7678352 BMEA_A0595 Brucella melitensis ATCC 23457 addiction module antidote YP_002732320.1 573279 R 546272 CDS YP_002732321.1 225852088 7678353 complement(573570..574562) 1 NC_012441.1 Mg2 transporter protein CorA family protein 574562 7678353 BMEA_A0596 Brucella melitensis ATCC 23457 Mg2 transporter protein CorA family protein YP_002732321.1 573570 R 546272 CDS YP_002732322.1 225852089 7678354 574718..575395 1 NC_012441.1 GntR family transcriptional regulator 575395 7678354 BMEA_A0597 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002732322.1 574718 D 546272 CDS YP_002732323.1 225852090 7678355 575392..576690 1 NC_012441.1 major facilitator superfamily protein 576690 7678355 BMEA_A0598 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002732323.1 575392 D 546272 CDS YP_002732324.1 225852091 7678356 complement(576747..577109) 1 NC_012441.1 hypothetical protein 577109 7678356 BMEA_A0599 Brucella melitensis ATCC 23457 hypothetical protein YP_002732324.1 576747 R 546272 CDS YP_002732325.1 225852092 7678357 577445..578956 1 NC_012441.1 hypothetical protein 578956 7678357 BMEA_A0600 Brucella melitensis ATCC 23457 hypothetical protein YP_002732325.1 577445 D 546272 CDS YP_002732326.1 225852093 7678358 578998..579096 1 NC_012441.1 hypothetical protein 579096 7678358 BMEA_A0601 Brucella melitensis ATCC 23457 hypothetical protein YP_002732326.1 578998 D 546272 CDS YP_002732327.1 225852094 7678359 complement(579154..579870) 1 NC_012441.1 ErfK/YbiS/YcfS/YnhG family protein 579870 7678359 BMEA_A0602 Brucella melitensis ATCC 23457 ErfK/YbiS/YcfS/YnhG family protein YP_002732327.1 579154 R 546272 CDS YP_002732328.1 225852095 7678361 581048..581647 1 NC_012441.1 superoxide dismutase 581647 7678361 BMEA_A0604 Brucella melitensis ATCC 23457 superoxide dismutase YP_002732328.1 581048 D 546272 CDS YP_002732329.1 225852096 7678362 complement(581819..582205) 1 NC_012441.1 hypothetical protein 582205 7678362 BMEA_A0606 Brucella melitensis ATCC 23457 hypothetical protein YP_002732329.1 581819 R 546272 CDS YP_002732330.1 225852097 7678363 complement(582272..584380) 1 NC_012441.1 protease 2 584380 7678363 BMEA_A0607 Brucella melitensis ATCC 23457 protease 2 YP_002732330.1 582272 R 546272 CDS YP_002732331.1 225852098 7678364 584804..584965 1 NC_012441.1 hypothetical protein 584965 7678364 BMEA_A0608 Brucella melitensis ATCC 23457 hypothetical protein YP_002732331.1 584804 D 546272 CDS YP_002732332.1 225852099 7678365 584953..585381 1 NC_012441.1 transcriptional regulator RosAr 585381 7678365 BMEA_A0609 Brucella melitensis ATCC 23457 transcriptional regulator RosAr YP_002732332.1 584953 D 546272 CDS YP_002732333.1 225852100 7678366 complement(585589..585900) 1 NC_012441.1 hypothetical protein 585900 7678366 BMEA_A0610 Brucella melitensis ATCC 23457 hypothetical protein YP_002732333.1 585589 R 546272 CDS YP_002732334.1 225852101 7678367 586082..586537 1 NC_012441.1 hypothetical protein 586537 7678367 BMEA_A0611 Brucella melitensis ATCC 23457 hypothetical protein YP_002732334.1 586082 D 546272 CDS YP_002732335.1 225852102 7678368 586534..587307 1 NC_012441.1 hypothetical protein 587307 7678368 BMEA_A0612 Brucella melitensis ATCC 23457 hypothetical protein YP_002732335.1 586534 D 546272 CDS YP_002732336.1 225852103 7678369 587420..588757 1 NC_012441.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 588757 7678369 BMEA_A0613 Brucella melitensis ATCC 23457 amidase YP_002732336.1 587420 D 546272 CDS YP_002732337.1 225852104 7678370 complement(588798..589223) 1 NC_012441.1 hypothetical protein 589223 7678370 BMEA_A0614 Brucella melitensis ATCC 23457 hypothetical protein YP_002732337.1 588798 R 546272 CDS YP_002732338.1 225852105 7678371 complement(589303..589752) 1 NC_012441.1 hypothetical protein 589752 7678371 BMEA_A0615 Brucella melitensis ATCC 23457 hypothetical protein YP_002732338.1 589303 R 546272 CDS YP_002732339.1 225852106 7678372 590043..591872 1 NC_012441.1 integral membrane sensor signal transduction histidine kinase 591872 7678372 BMEA_A0616 Brucella melitensis ATCC 23457 integral membrane sensor signal transduction histidine kinase YP_002732339.1 590043 D 546272 CDS YP_002732340.1 225852107 7678373 591799..592815 1 NC_012441.1 peptidoglycan-binding domain 1 protein 592815 7678373 BMEA_A0617 Brucella melitensis ATCC 23457 peptidoglycan-binding domain 1 protein YP_002732340.1 591799 D 546272 CDS YP_002732341.1 225852108 7678374 592829..593176 1 NC_012441.1 hypothetical protein 593176 7678374 BMEA_A0618 Brucella melitensis ATCC 23457 hypothetical protein YP_002732341.1 592829 D 546272 CDS YP_002732342.1 225852109 7678375 complement(593187..594245) 1 NC_012441.1 hypothetical protein 594245 7678375 BMEA_A0619 Brucella melitensis ATCC 23457 hypothetical protein YP_002732342.1 593187 R 546272 CDS YP_002732343.1 225852110 7678376 complement(594443..594985) 1 NC_012441.1 hypothetical protein 594985 7678376 BMEA_A0620 Brucella melitensis ATCC 23457 hypothetical protein YP_002732343.1 594443 R 546272 CDS YP_002732344.1 225852111 7678377 complement(594978..595589) 1 NC_012441.1 hypothetical protein 595589 7678377 BMEA_A0621 Brucella melitensis ATCC 23457 hypothetical protein YP_002732344.1 594978 R 546272 CDS YP_002732345.1 225852112 7678378 complement(595596..597752) 1 NC_012441.1 1A family penicillin-binding protein 597752 7678378 BMEA_A0622 Brucella melitensis ATCC 23457 1A family penicillin-binding protein YP_002732345.1 595596 R 546272 CDS YP_002732346.1 225852113 7678379 598585..599820 1 NC_012441.1 hypothetical protein 599820 7678379 BMEA_A0624 Brucella melitensis ATCC 23457 hypothetical protein YP_002732346.1 598585 D 546272 CDS YP_002732347.1 225852114 7678380 599852..601045 1 NC_012441.1 phage portal protein 601045 7678380 BMEA_A0625 Brucella melitensis ATCC 23457 phage portal protein YP_002732347.1 599852 D 546272 CDS YP_002732348.1 225852115 7678381 601042..601419 1 NC_012441.1 hypothetical protein 601419 7678381 BMEA_A0626 Brucella melitensis ATCC 23457 hypothetical protein YP_002732348.1 601042 D 546272 CDS YP_002732349.1 225852116 7676284 602097..603371 1 NC_012441.1 phage major capsid protein 603371 7676284 BMEA_A0628 Brucella melitensis ATCC 23457 phage major capsid protein YP_002732349.1 602097 D 546272 CDS YP_002732350.1 225852117 7676285 603536..604102 1 NC_012441.1 hypothetical protein 604102 7676285 BMEA_A0629 Brucella melitensis ATCC 23457 hypothetical protein YP_002732350.1 603536 D 546272 CDS YP_002732351.1 225852118 7676286 604099..604437 1 NC_012441.1 phage head-tail adaptor 604437 7676286 BMEA_A0630 Brucella melitensis ATCC 23457 phage head-tail adaptor YP_002732351.1 604099 D 546272 CDS YP_002732352.1 225852119 7676287 604559..604966 1 NC_012441.1 hypothetical protein 604966 7676287 BMEA_A0631 Brucella melitensis ATCC 23457 hypothetical protein YP_002732352.1 604559 D 546272 CDS YP_002732353.1 225852120 7676288 605007..605420 1 NC_012441.1 phage major tail protein 605420 7676288 BMEA_A0632 Brucella melitensis ATCC 23457 phage major tail protein YP_002732353.1 605007 D 546272 CDS YP_002732354.1 225852121 7676289 605417..605758 1 NC_012441.1 hypothetical protein 605758 7676289 BMEA_A0633 Brucella melitensis ATCC 23457 hypothetical protein YP_002732354.1 605417 D 546272 CDS YP_002732355.1 225852122 7676290 605802..605972 1 NC_012441.1 hypothetical protein 605972 7676290 BMEA_A0634 Brucella melitensis ATCC 23457 hypothetical protein YP_002732355.1 605802 D 546272 CDS YP_002732356.1 225852123 7676291 605977..606522 1 NC_012441.1 hypothetical protein 606522 7676291 BMEA_A0635 Brucella melitensis ATCC 23457 hypothetical protein YP_002732356.1 605977 D 546272 CDS YP_002732357.1 225852124 7676292 606525..607157 1 NC_012441.1 hypothetical protein 607157 7676292 BMEA_A0636 Brucella melitensis ATCC 23457 hypothetical protein YP_002732357.1 606525 D 546272 CDS YP_002732358.1 225852125 7676293 607154..608029 1 NC_012441.1 hypothetical protein 608029 7676293 BMEA_A0637 Brucella melitensis ATCC 23457 hypothetical protein YP_002732358.1 607154 D 546272 CDS YP_002732359.1 225852126 7676294 608026..608460 1 NC_012441.1 phage cell wall peptidase NlpC/P60 family protein 608460 7676294 BMEA_A0638 Brucella melitensis ATCC 23457 phage cell wall peptidase NlpC/P60 family protein YP_002732359.1 608026 D 546272 CDS YP_002732360.1 225852127 7676296 612390..612596 1 NC_012441.1 hypothetical protein 612596 7676296 BMEA_A0640 Brucella melitensis ATCC 23457 hypothetical protein YP_002732360.1 612390 D 546272 CDS YP_002732361.1 225852128 7676297 612758..613054 1 NC_012441.1 hypothetical protein 613054 7676297 BMEA_A0641 Brucella melitensis ATCC 23457 hypothetical protein YP_002732361.1 612758 D 546272 CDS YP_002732362.1 225852129 7676298 613133..613822 1 NC_012441.1 winged helix family two component transcriptional regulator 613822 7676298 BMEA_A0642 Brucella melitensis ATCC 23457 winged helix family two component transcriptional regulator YP_002732362.1 613133 D 546272 CDS YP_002732363.1 225852130 7676299 613972..615207 1 NC_012441.1 histidine kinase 615207 7676299 BMEA_A0643 Brucella melitensis ATCC 23457 histidine kinase YP_002732363.1 613972 D 546272 CDS YP_002732364.1 225852131 7676300 615268..615753 1 NC_012441.1 outer membrane lipoprotein-related protein 615753 7676300 BMEA_A0644 Brucella melitensis ATCC 23457 outer membrane lipoprotein-related protein YP_002732364.1 615268 D 546272 CDS YP_002732365.1 225852132 7676301 615854..616993 1 NC_012441.1 cytochrome c-type biogenesis protein CcmI 616993 ccmI 7676301 ccmI Brucella melitensis ATCC 23457 cytochrome c-type biogenesis protein CcmI YP_002732365.1 615854 D 546272 CDS YP_002732366.1 225852133 7676302 616990..617487 1 NC_012441.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 617487 7676302 BMEA_A0646 Brucella melitensis ATCC 23457 cytochrome c-type biogenesis protein CcmE YP_002732366.1 616990 D 546272 CDS YP_002732367.1 225852134 7676303 617507..619498 1 NC_012441.1 cytochrome c-type biogenesis protein CcmF 619498 ccmF 7676303 ccmF Brucella melitensis ATCC 23457 cytochrome c-type biogenesis protein CcmF YP_002732367.1 617507 D 546272 CDS YP_002732368.1 225852135 7676304 619495..619971 1 NC_012441.1 cytochrome c-type biogenesis protein ccl2 619971 7676304 BMEA_A0648 Brucella melitensis ATCC 23457 cytochrome c-type biogenesis protein ccl2 YP_002732368.1 619495 D 546272 CDS YP_002732369.1 225852136 7676305 620113..621654 1 NC_012441.1 protease Do 621654 degP 7676305 degP Brucella melitensis ATCC 23457 protease Do YP_002732369.1 620113 D 546272 CDS YP_002732370.1 225852137 7676306 621748..622455 1 NC_012441.1 transcriptional activator protein copR 622455 7676306 BMEA_A0650 Brucella melitensis ATCC 23457 transcriptional activator protein copR YP_002732370.1 621748 D 546272 CDS YP_002732371.1 225852138 7676307 622455..623858 1 NC_012441.1 integral membrane sensor signal transduction histidine kinase 623858 7676307 BMEA_A0651 Brucella melitensis ATCC 23457 integral membrane sensor signal transduction histidine kinase YP_002732371.1 622455 D 546272 CDS YP_002732372.1 225852139 7676308 623981..626932 1 NC_012441.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 626932 7676308 BMEA_A0652 Brucella melitensis ATCC 23457 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002732372.1 623981 D 546272 CDS YP_002732373.1 225852140 7676309 complement(626977..629088) 1 NC_012441.1 glycosyltransferase 25 family protein 629088 7676309 BMEA_A0653 Brucella melitensis ATCC 23457 glycosyltransferase 25 family protein YP_002732373.1 626977 R 546272 CDS YP_002732374.1 225852141 7676310 complement(629359..631710) 1 NC_012441.1 PAS domain S-box-containing protein 631710 7676310 BMEA_A0654 Brucella melitensis ATCC 23457 PAS domain S-box-containing protein YP_002732374.1 629359 R 546272 CDS YP_002732375.1 225852142 7676311 complement(632101..634752) 1 NC_012441.1 aminopeptidase N 634752 pepN 7676311 pepN Brucella melitensis ATCC 23457 aminopeptidase N YP_002732375.1 632101 R 546272 CDS YP_002732376.1 225852143 7676312 634921..635937 1 NC_012441.1 hypothetical protein 635937 7676312 BMEA_A0656 Brucella melitensis ATCC 23457 hypothetical protein YP_002732376.1 634921 D 546272 CDS YP_002732377.1 225852144 7676313 complement(635942..637198) 1 NC_012441.1 major facilitator superfamily protein 637198 7676313 BMEA_A0657 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002732377.1 635942 R 546272 CDS YP_002732378.1 225852145 7676314 complement(637360..638232) 1 NC_012441.1 uracil-DNA glycosylase 638232 7676314 BMEA_A0658 Brucella melitensis ATCC 23457 uracil-DNA glycosylase YP_002732378.1 637360 R 546272 CDS YP_002732379.1 225852146 7676315 638621..640312 1 NC_012441.1 electron-transferring-flavoprotein dehydrogenase 640312 7676315 BMEA_A0659 Brucella melitensis ATCC 23457 electron-transferring-flavoprotein dehydrogenase YP_002732379.1 638621 D 546272 CDS YP_002732380.1 225852147 7676316 complement(640428..641504) 1 NC_012441.1 hypothetical protein 641504 7676316 BMEA_A0660 Brucella melitensis ATCC 23457 hypothetical protein YP_002732380.1 640428 R 546272 CDS YP_002732381.1 225852148 7676317 complement(641557..643059) 1 NC_012441.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 643059 amn 7676317 amn Brucella melitensis ATCC 23457 AMP nucleosidase YP_002732381.1 641557 R 546272 CDS YP_002732382.1 225852149 7676318 643112..643270 1 NC_012441.1 hypothetical protein 643270 7676318 BMEA_A0663 Brucella melitensis ATCC 23457 hypothetical protein YP_002732382.1 643112 D 546272 CDS YP_002732383.1 225852150 7676319 643267..643548 1 NC_012441.1 hypothetical protein 643548 7676319 BMEA_A0664 Brucella melitensis ATCC 23457 hypothetical protein YP_002732383.1 643267 D 546272 CDS YP_002732384.1 225852151 7676320 643626..644336 1 NC_012441.1 glutathione S-transferase domain-containing protein 644336 7676320 BMEA_A0665 Brucella melitensis ATCC 23457 glutathione S-transferase domain-containing protein YP_002732384.1 643626 D 546272 CDS YP_002732385.1 225852152 7676321 complement(644395..644742) 1 NC_012441.1 hypothetical protein 644742 7676321 BMEA_A0666 Brucella melitensis ATCC 23457 hypothetical protein YP_002732385.1 644395 R 546272 CDS YP_002732386.1 225852153 7676322 complement(644739..645029) 1 NC_012441.1 hypothetical protein 645029 7676322 BMEA_A0667 Brucella melitensis ATCC 23457 hypothetical protein YP_002732386.1 644739 R 546272 CDS YP_002732387.1 225852154 7676323 645248..645505 1 NC_012441.1 hypothetical protein 645505 7676323 BMEA_A0668 Brucella melitensis ATCC 23457 hypothetical protein YP_002732387.1 645248 D 546272 CDS YP_002732388.1 225852155 7676324 complement(645565..646338) 1 NC_012441.1 hypothetical protein 646338 7676324 BMEA_A0669 Brucella melitensis ATCC 23457 hypothetical protein YP_002732388.1 645565 R 546272 CDS YP_002732389.1 225852156 7676325 646601..646696 1 NC_012441.1 hypothetical protein 646696 7676325 BMEA_A0670 Brucella melitensis ATCC 23457 hypothetical protein YP_002732389.1 646601 D 546272 CDS YP_002732390.1 225852157 7676326 646990..647640 1 NC_012441.1 hypothetical protein 647640 7676326 BMEA_A0671 Brucella melitensis ATCC 23457 hypothetical protein YP_002732390.1 646990 D 546272 CDS YP_002732391.1 225852158 7676327 complement(647685..648059) 1 NC_012441.1 oxidoreductase Gfo/Idh/MocA family protein 648059 7676327 BMEA_A0672 Brucella melitensis ATCC 23457 oxidoreductase Gfo/Idh/MocA family protein YP_002732391.1 647685 R 546272 CDS YP_002732392.1 225852159 7676328 complement(648077..649210) 1 NC_012441.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; histidinol-phosphate aminotransferase 649210 7676328 BMEA_A0673 Brucella melitensis ATCC 23457 histidinol-phosphate aminotransferase YP_002732392.1 648077 R 546272 CDS YP_002732393.1 225852160 7676329 complement(649573..650499) 1 NC_012441.1 tyrosine recombinase XerC 650499 7676329 BMEA_A0674 Brucella melitensis ATCC 23457 tyrosine recombinase XerC YP_002732393.1 649573 R 546272 CDS YP_002732394.1 225852161 7676330 complement(650774..651877) 1 NC_012441.1 outer membrane protein IIIA precursor 651877 7676330 BMEA_A0675 Brucella melitensis ATCC 23457 outer membrane protein IIIA precursor YP_002732394.1 650774 R 546272 CDS YP_002732395.1 225852162 7676332 652678..653805 1 NC_012441.1 outer membrane protein IIIA precursor 653805 7676332 BMEA_A0677 Brucella melitensis ATCC 23457 outer membrane protein IIIA precursor YP_002732395.1 652678 D 546272 CDS YP_002732396.1 225852163 7676333 653949..654590 1 NC_012441.1 hypothetical protein 654590 7676333 BMEA_A0678 Brucella melitensis ATCC 23457 hypothetical protein YP_002732396.1 653949 D 546272 CDS YP_002732397.1 225852164 7676334 654646..654828 1 NC_012441.1 hypothetical protein 654828 7676334 BMEA_A0679 Brucella melitensis ATCC 23457 hypothetical protein YP_002732397.1 654646 D 546272 CDS YP_002732398.1 225852165 7676335 654889..655563 1 NC_012441.1 50S ribosomal protein L21 655563 7676335 BMEA_A0680 Brucella melitensis ATCC 23457 50S ribosomal protein L21 YP_002732398.1 654889 D 546272 CDS YP_002732399.1 225852166 7676336 complement(655626..657683) 1 NC_012441.1 lytic transglycosylase 657683 7676336 BMEA_A0681 Brucella melitensis ATCC 23457 lytic transglycosylase YP_002732399.1 655626 R 546272 CDS YP_002732400.1 225852167 7676337 658159..659040 1 NC_012441.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 659040 dapA 7676337 dapA Brucella melitensis ATCC 23457 dihydrodipicolinate synthase YP_002732400.1 658159 D 546272 CDS YP_002732401.1 225852168 7676338 659131..659607 1 NC_012441.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 659607 smpB 7676338 smpB Brucella melitensis ATCC 23457 SsrA-binding protein YP_002732401.1 659131 D 546272 CDS YP_002732402.1 225852169 7676339 complement(659744..660415) 1 NC_012441.1 uracil-DNA glycosylase superfamily protein 660415 7676339 BMEA_A0685 Brucella melitensis ATCC 23457 uracil-DNA glycosylase superfamily protein YP_002732402.1 659744 R 546272 CDS YP_002732403.1 225852170 7676340 complement(660446..661021) 1 NC_012441.1 hypothetical protein 661021 7676340 BMEA_A0686 Brucella melitensis ATCC 23457 hypothetical protein YP_002732403.1 660446 R 546272 CDS YP_002732404.1 225852171 7676341 complement(661221..661376) 1 NC_012441.1 hypothetical protein 661376 7676341 BMEA_A0687 Brucella melitensis ATCC 23457 hypothetical protein YP_002732404.1 661221 R 546272 CDS YP_002732405.1 225852172 7676342 661418..661819 1 NC_012441.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 661819 rpoZ 7676342 rpoZ Brucella melitensis ATCC 23457 DNA-directed RNA polymerase subunit omega YP_002732405.1 661418 D 546272 CDS YP_002732406.1 225852173 7676343 662060..664312 1 NC_012441.1 RelA/SpoT family protein 664312 7676343 BMEA_A0689 Brucella melitensis ATCC 23457 RelA/SpoT family protein YP_002732406.1 662060 D 546272 CDS YP_002732407.1 225852174 7676344 664320..664898 1 NC_012441.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 664898 pyrE 7676344 pyrE Brucella melitensis ATCC 23457 orotate phosphoribosyltransferase YP_002732407.1 664320 D 546272 CDS YP_002732408.1 225852175 7676345 665058..665813 1 NC_012441.1 transcriptional activator protein fnrA 665813 7676345 BMEA_A0691 Brucella melitensis ATCC 23457 transcriptional activator protein fnrA YP_002732408.1 665058 D 546272 CDS YP_002732409.1 225852176 7676346 666194..667528 1 NC_012441.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 667528 hemN 7676346 hemN Brucella melitensis ATCC 23457 coproporphyrinogen III oxidase YP_002732409.1 666194 D 546272 CDS YP_002732410.1 225852177 7676347 complement(667712..668923) 1 NC_012441.1 major facilitator superfamily protein 668923 7676347 BMEA_A0693 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002732410.1 667712 R 546272 CDS YP_002732411.1 225852178 7676348 669175..670014 1 NC_012441.1 AraC family transcriptional regulator 670014 7676348 BMEA_A0694 Brucella melitensis ATCC 23457 AraC family transcriptional regulator YP_002732411.1 669175 D 546272 CDS YP_002732412.1 225852179 7676349 670064..670639 1 NC_012441.1 hypothetical protein 670639 7676349 BMEA_A0695 Brucella melitensis ATCC 23457 hypothetical protein YP_002732412.1 670064 D 546272 CDS YP_002732413.1 225852180 7676350 670636..671040 1 NC_012441.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 671040 acpS 7676350 acpS Brucella melitensis ATCC 23457 4'-phosphopantetheinyl transferase YP_002732413.1 670636 D 546272 CDS YP_002732414.1 225852181 7676351 671151..671933 1 NC_012441.1 signal peptidase I 671933 lepB 7676351 lepB Brucella melitensis ATCC 23457 signal peptidase I YP_002732414.1 671151 D 546272 CDS YP_002732415.1 225852182 7676352 671902..672639 1 NC_012441.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 672639 rnc 7676352 rnc Brucella melitensis ATCC 23457 ribonuclease III YP_002732415.1 671902 D 546272 CDS YP_002732416.1 225852183 7676353 672682..672780 1 NC_012441.1 hypothetical protein 672780 7676353 BMEA_A0699 Brucella melitensis ATCC 23457 hypothetical protein YP_002732416.1 672682 D 546272 CDS YP_002732417.1 225852184 7676354 672784..673719 1 NC_012441.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 673719 era 7676354 era Brucella melitensis ATCC 23457 GTP-binding protein Era YP_002732417.1 672784 D 546272 CDS YP_002732418.1 225852185 7676355 673746..674489 1 NC_012441.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 674489 recO 7676355 recO Brucella melitensis ATCC 23457 DNA repair protein RecO YP_002732418.1 673746 D 546272 CDS YP_002732419.1 225852186 7676356 complement(674467..674976) 1 NC_012441.1 hypothetical protein 674976 7676356 BMEA_A0702 Brucella melitensis ATCC 23457 hypothetical protein YP_002732419.1 674467 R 546272 CDS YP_002732420.1 225852187 7676357 complement(674973..675593) 1 NC_012441.1 hypothetical protein 675593 7676357 BMEA_A0703 Brucella melitensis ATCC 23457 hypothetical protein YP_002732420.1 674973 R 546272 CDS YP_002732421.1 225852188 7676358 complement(675593..676456) 1 NC_012441.1 folate-binding protein YgfZ 676456 ygfZ 7676358 ygfZ Brucella melitensis ATCC 23457 folate-binding protein YgfZ YP_002732421.1 675593 R 546272 CDS YP_002732422.1 225852189 7676359 676542..677876 1 NC_012441.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 677876 pyrC 7676359 pyrC Brucella melitensis ATCC 23457 dihydroorotase YP_002732422.1 676542 D 546272 CDS YP_002732423.1 225852190 7676360 complement(677925..678689) 1 NC_012441.1 hypothetical protein 678689 7676360 BMEA_A0706 Brucella melitensis ATCC 23457 hypothetical protein YP_002732423.1 677925 R 546272 CDS YP_002732424.1 225852191 7676361 complement(678738..679004) 1 NC_012441.1 hypothetical protein 679004 7676361 BMEA_A0707 Brucella melitensis ATCC 23457 hypothetical protein YP_002732424.1 678738 R 546272 CDS YP_002732425.1 225852192 7676362 complement(679161..679544) 1 NC_012441.1 hypothetical protein 679544 7676362 BMEA_A0708 Brucella melitensis ATCC 23457 hypothetical protein YP_002732425.1 679161 R 546272 CDS YP_002732426.1 225852193 7676363 complement(679624..680067) 1 NC_012441.1 NUDIX hydrolase 680067 7676363 BMEA_A0709 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002732426.1 679624 R 546272 CDS YP_002732427.1 225852194 7676364 680153..680932 1 NC_012441.1 hypothetical protein 680932 7676364 BMEA_A0710 Brucella melitensis ATCC 23457 hypothetical protein YP_002732427.1 680153 D 546272 CDS YP_002732428.1 225852195 7677394 680987..681601 1 NC_012441.1 amino-acid transporter yggA 681601 7677394 BMEA_A0711 Brucella melitensis ATCC 23457 amino-acid transporter yggA YP_002732428.1 680987 D 546272 CDS YP_002732429.1 225852196 7676850 complement(681578..681745) 1 NC_012441.1 hypothetical protein 681745 7676850 BMEA_A0712 Brucella melitensis ATCC 23457 hypothetical protein YP_002732429.1 681578 R 546272 CDS YP_002732430.1 225852197 7676851 complement(681750..681965) 1 NC_012441.1 hypothetical protein 681965 7676851 BMEA_A0713 Brucella melitensis ATCC 23457 hypothetical protein YP_002732430.1 681750 R 546272 CDS YP_002732431.1 225852198 7676852 682112..683632 1 NC_012441.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 683632 cysS 7676852 cysS Brucella melitensis ATCC 23457 cysteinyl-tRNA synthetase YP_002732431.1 682112 D 546272 CDS YP_002732432.1 225852199 7676853 683651..685264 1 NC_012441.1 putative alpha-isopropylmalate/homocitrate synthase family transferase 685264 7676853 BMEA_A0715 Brucella melitensis ATCC 23457 putative alpha-isopropylmalate/homocitrate synthase family transferase YP_002732432.1 683651 D 546272 CDS YP_002732433.1 225852200 7676854 685515..686435 1 NC_012441.1 RarD protein 686435 rarD 7676854 rarD Brucella melitensis ATCC 23457 RarD protein YP_002732433.1 685515 D 546272 CDS YP_002732434.1 225852201 7676855 686568..688301 1 NC_012441.1 peptidase M23B 688301 7676855 BMEA_A0717 Brucella melitensis ATCC 23457 peptidase M23B YP_002732434.1 686568 D 546272 CDS YP_002732435.1 225852202 7676856 complement(688369..689199) 1 NC_012441.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 689199 ksgA 7676856 ksgA Brucella melitensis ATCC 23457 dimethyladenosine transferase YP_002732435.1 688369 R 546272 CDS YP_002732436.1 225852203 7676857 complement(689196..690227) 1 NC_012441.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 690227 pdxA 7676857 pdxA Brucella melitensis ATCC 23457 4-hydroxythreonine-4-phosphate dehydrogenase YP_002732436.1 689196 R 546272 CDS YP_002732437.1 225852204 7676858 complement(690292..691248) 1 NC_012441.1 chaperone SurA 691248 7676858 BMEA_A0720 Brucella melitensis ATCC 23457 chaperone SurA YP_002732437.1 690292 R 546272 CDS YP_002732438.1 225852205 7676859 complement(691576..693954) 1 NC_012441.1 LPS-assembly protein 693954 7676859 BMEA_A0721 Brucella melitensis ATCC 23457 LPS-assembly protein YP_002732438.1 691576 R 546272 CDS YP_002732439.1 225852206 7676860 complement(693975..695063) 1 NC_012441.1 YjgP/YjgQ family permease 695063 7676860 BMEA_A0722 Brucella melitensis ATCC 23457 YjgP/YjgQ family permease YP_002732439.1 693975 R 546272 CDS YP_002732440.1 225852207 7676861 complement(695060..696268) 1 NC_012441.1 YjgP/YjgQ family permease 696268 7676861 BMEA_A0723 Brucella melitensis ATCC 23457 YjgP/YjgQ family permease YP_002732440.1 695060 R 546272 CDS YP_002732441.1 225852208 7676862 complement(696441..696605) 1 NC_012441.1 hypothetical protein 696605 7676862 BMEA_A0724 Brucella melitensis ATCC 23457 hypothetical protein YP_002732441.1 696441 R 546272 CDS YP_002732442.1 225852209 7676863 696678..698171 1 NC_012441.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 698171 7676863 BMEA_A0725 Brucella melitensis ATCC 23457 leucyl aminopeptidase YP_002732442.1 696678 D 546272 CDS YP_002732443.1 225852210 7676864 698243..698692 1 NC_012441.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 698692 7676864 BMEA_A0726 Brucella melitensis ATCC 23457 DNA polymerase III subunit chi YP_002732443.1 698243 D 546272 CDS YP_002732444.1 225852211 7676865 698692..699255 1 NC_012441.1 hypothetical protein 699255 7676865 BMEA_A0727 Brucella melitensis ATCC 23457 hypothetical protein YP_002732444.1 698692 D 546272 CDS YP_002732445.1 225852212 7676866 complement(699315..701255) 1 NC_012441.1 ATP-binding protein 701255 7676866 BMEA_A0728 Brucella melitensis ATCC 23457 ATP-binding protein YP_002732445.1 699315 R 546272 CDS YP_002732446.1 225852213 7676867 complement(701259..701771) 1 NC_012441.1 DinB family protein 701771 7676867 BMEA_A0729 Brucella melitensis ATCC 23457 DinB family protein YP_002732446.1 701259 R 546272 CDS YP_002732447.1 225852214 7676868 702000..702422 1 NC_012441.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 702422 7676868 BMEA_A0730 Brucella melitensis ATCC 23457 nucleoside diphosphate kinase YP_002732447.1 702000 D 546272 CDS YP_002732448.1 225852215 7676869 complement(702532..703335) 1 NC_012441.1 hypothetical protein 703335 7676869 BMEA_A0731 Brucella melitensis ATCC 23457 hypothetical protein YP_002732448.1 702532 R 546272 CDS YP_002732449.1 225852216 7676870 complement(703573..704064) 1 NC_012441.1 molybdopterin biosynthesis MoaE protein 704064 7676870 BMEA_A0732 Brucella melitensis ATCC 23457 molybdopterin biosynthesis MoaE protein YP_002732449.1 703573 R 546272 CDS YP_002732450.1 225852217 7676871 complement(704066..704323) 1 NC_012441.1 molybdopterin converting factor subunit 1 704323 moaD 7676871 moaD Brucella melitensis ATCC 23457 molybdopterin converting factor subunit 1 YP_002732450.1 704066 R 546272 CDS YP_002732451.1 225852218 7676872 complement(704328..704912) 1 NC_012441.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 704912 pgsA 7676872 pgsA Brucella melitensis ATCC 23457 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002732451.1 704328 R 546272 CDS YP_002732452.1 225852219 7676873 complement(705031..707088) 1 NC_012441.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 707088 uvrC 7676873 uvrC Brucella melitensis ATCC 23457 excinuclease ABC subunit C YP_002732452.1 705031 R 546272 CDS YP_002732453.1 225852220 7676874 complement(707088..707843) 1 NC_012441.1 short chain dehydrogenase 707843 7676874 BMEA_A0736 Brucella melitensis ATCC 23457 short chain dehydrogenase YP_002732453.1 707088 R 546272 CDS YP_002732454.1 225852221 7676875 708048..708206 1 NC_012441.1 hypothetical protein 708206 7676875 BMEA_A0737 Brucella melitensis ATCC 23457 hypothetical protein YP_002732454.1 708048 D 546272 CDS YP_002732455.1 225852222 7676876 708245..708886 1 NC_012441.1 OmpA-like transmembrane domain-containing protein 708886 7676876 BMEA_A0738 Brucella melitensis ATCC 23457 OmpA-like transmembrane domain-containing protein YP_002732455.1 708245 D 546272 CDS YP_002732456.1 225852223 7676877 complement(708983..709582) 1 NC_012441.1 glutathione S-transferase domain-containing protein 709582 7676877 BMEA_A0739 Brucella melitensis ATCC 23457 glutathione S-transferase domain-containing protein YP_002732456.1 708983 R 546272 CDS YP_002732457.1 225852224 7676878 complement(709637..710326) 1 NC_012441.1 ribonuclease 710326 7676878 BMEA_A0741 Brucella melitensis ATCC 23457 ribonuclease YP_002732457.1 709637 R 546272 CDS YP_002732458.1 225852225 7676879 complement(710339..710809) 1 NC_012441.1 hypothetical protein 710809 7676879 BMEA_A0742 Brucella melitensis ATCC 23457 hypothetical protein YP_002732458.1 710339 R 546272 CDS YP_002732459.1 225852226 7676880 complement(710892..711764) 1 NC_012441.1 hypothetical protein 711764 7676880 BMEA_A0743 Brucella melitensis ATCC 23457 hypothetical protein YP_002732459.1 710892 R 546272 CDS YP_002732460.1 225852227 7676881 711920..712765 1 NC_012441.1 hypothetical protein 712765 7676881 BMEA_A0744 Brucella melitensis ATCC 23457 hypothetical protein YP_002732460.1 711920 D 546272 CDS YP_002732461.1 225852228 7676882 712843..714969 1 NC_012441.1 nitrate reductase 714969 7676882 BMEA_A0745 Brucella melitensis ATCC 23457 nitrate reductase YP_002732461.1 712843 D 546272 CDS YP_002732462.1 225852229 7676883 complement(715095..715619) 1 NC_012441.1 hypothetical protein 715619 7676883 BMEA_A0746 Brucella melitensis ATCC 23457 hypothetical protein YP_002732462.1 715095 R 546272 CDS YP_002732463.1 225852230 7676884 complement(715795..716412) 1 NC_012441.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 716412 purN 7676884 purN Brucella melitensis ATCC 23457 phosphoribosylglycinamide formyltransferase YP_002732463.1 715795 R 546272 CDS YP_002732464.1 225852231 7676885 complement(716409..717488) 1 NC_012441.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 717488 purM 7676885 purM Brucella melitensis ATCC 23457 phosphoribosylaminoimidazole synthetase YP_002732464.1 716409 R 546272 CDS YP_002732465.1 225852232 7676886 complement(717530..717709) 1 NC_012441.1 hypothetical protein 717709 7676886 BMEA_A0749 Brucella melitensis ATCC 23457 hypothetical protein YP_002732465.1 717530 R 546272 CDS YP_002732466.1 225852233 7676887 717978..719126 1 NC_012441.1 hypothetical protein 719126 7676887 BMEA_A0750 Brucella melitensis ATCC 23457 hypothetical protein YP_002732466.1 717978 D 546272 CDS YP_002732467.1 225852234 7676888 719166..719861 1 NC_012441.1 hypothetical protein 719861 7676888 BMEA_A0751 Brucella melitensis ATCC 23457 hypothetical protein YP_002732467.1 719166 D 546272 CDS YP_002732468.1 225852235 7676889 719858..720727 1 NC_012441.1 UDP-glucose 4-epimerase 720727 7676889 BMEA_A0752 Brucella melitensis ATCC 23457 UDP-glucose 4-epimerase YP_002732468.1 719858 D 546272 CDS YP_002732469.1 225852236 7676890 complement(720724..721509) 1 NC_012441.1 hypothetical protein 721509 7676890 BMEA_A0753 Brucella melitensis ATCC 23457 hypothetical protein YP_002732469.1 720724 R 546272 CDS YP_002732470.1 225852237 7676891 complement(721582..722286) 1 NC_012441.1 oxidoreductase, short-chain dehydrogenase/reductase family protein 722286 7676891 BMEA_A0754 Brucella melitensis ATCC 23457 oxidoreductase, short-chain dehydrogenase/reductase family protein YP_002732470.1 721582 R 546272 CDS YP_002732471.1 225852238 7676892 complement(722448..722663) 1 NC_012441.1 hypothetical protein 722663 7676892 BMEA_A0755 Brucella melitensis ATCC 23457 hypothetical protein YP_002732471.1 722448 R 546272 CDS YP_002732472.1 225852239 7676893 722677..722832 1 NC_012441.1 hypothetical protein 722832 7676893 BMEA_A0756 Brucella melitensis ATCC 23457 hypothetical protein YP_002732472.1 722677 D 546272 CDS YP_002732473.1 225852240 7676896 725203..725508 1 NC_012441.1 ETC complex I subunit protein 725508 7676896 BMEA_A0759 Brucella melitensis ATCC 23457 ETC complex I subunit protein YP_002732473.1 725203 D 546272 CDS YP_002732474.1 225852241 7676898 726074..726664 1 NC_012441.1 hypothetical protein 726664 7676898 BMEA_A0761 Brucella melitensis ATCC 23457 hypothetical protein YP_002732474.1 726074 D 546272 CDS YP_002732475.1 225852242 7676899 complement(726885..727496) 1 NC_012441.1 exonuclease 727496 7676899 BMEA_A0762 Brucella melitensis ATCC 23457 exonuclease YP_002732475.1 726885 R 546272 CDS YP_002732476.1 225852243 7676900 727807..728139 1 NC_012441.1 transposase 728139 7676900 BMEA_A0763 Brucella melitensis ATCC 23457 transposase YP_002732476.1 727807 D 546272 CDS YP_002732477.1 225852244 7676901 complement(728665..729210) 1 NC_012441.1 ATP synthase subunit beta 729210 7676901 BMEA_A0764 Brucella melitensis ATCC 23457 ATP synthase subunit beta YP_002732477.1 728665 R 546272 CDS YP_002732478.1 225852245 7676902 complement(729207..730742) 1 NC_012441.1 N-acetyltransferase GCN5 730742 7676902 BMEA_A0765 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002732478.1 729207 R 546272 CDS YP_002732479.1 225852246 7676903 complement(730717..731511) 1 NC_012441.1 helix-turn-helix domain-containing protein 731511 7676903 BMEA_A0766 Brucella melitensis ATCC 23457 helix-turn-helix domain-containing protein YP_002732479.1 730717 R 546272 CDS YP_002732480.1 225852247 7676904 complement(731536..731955) 1 NC_012441.1 hypothetical protein 731955 7676904 BMEA_A0767 Brucella melitensis ATCC 23457 hypothetical protein YP_002732480.1 731536 R 546272 CDS YP_002732481.1 225852248 7676905 732335..733231 1 NC_012441.1 hypothetical protein 733231 7676905 BMEA_A0768 Brucella melitensis ATCC 23457 hypothetical protein YP_002732481.1 732335 D 546272 CDS YP_002732482.1 225852249 7676906 733231..735345 1 NC_012441.1 integrase catalytic domain-containing protein 735345 7676906 BMEA_A0769 Brucella melitensis ATCC 23457 integrase catalytic domain-containing protein YP_002732482.1 733231 D 546272 CDS YP_002732483.1 225852250 7676909 complement(738159..738356) 1 NC_012441.1 hypothetical protein 738356 7676909 BMEA_A0772 Brucella melitensis ATCC 23457 hypothetical protein YP_002732483.1 738159 R 546272 CDS YP_002732484.1 225852251 7676910 738597..739904 1 NC_012441.1 hypothetical protein 739904 7676910 BMEA_A0773 Brucella melitensis ATCC 23457 hypothetical protein YP_002732484.1 738597 D 546272 CDS YP_002732485.1 225852252 7676911 740358..741731 1 NC_012441.1 hypothetical protein 741731 7676911 BMEA_A0774 Brucella melitensis ATCC 23457 hypothetical protein YP_002732485.1 740358 D 546272 CDS YP_002732486.1 225852253 7676912 741820..742698 1 NC_012441.1 hypothetical protein 742698 7676912 BMEA_A0775 Brucella melitensis ATCC 23457 hypothetical protein YP_002732486.1 741820 D 546272 CDS YP_002732487.1 225852254 7676913 complement(743082..743594) 1 NC_012441.1 SH3 type 3 domain-containing protein 743594 7676913 BMEA_A0776 Brucella melitensis ATCC 23457 SH3 type 3 domain-containing protein YP_002732487.1 743082 R 546272 CDS YP_002732488.1 225852255 7676914 complement(743754..744002) 1 NC_012441.1 lipoprotein 744002 7676914 BMEA_A0777 Brucella melitensis ATCC 23457 lipoprotein YP_002732488.1 743754 R 546272 CDS YP_002732489.1 225852256 7676915 complement(744105..744260) 1 NC_012441.1 hypothetical protein 744260 7676915 BMEA_A0778 Brucella melitensis ATCC 23457 hypothetical protein YP_002732489.1 744105 R 546272 CDS YP_002732490.1 225852257 7676916 complement(744247..745416) 1 NC_012441.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 745416 metC 7676916 metC Brucella melitensis ATCC 23457 cystathionine beta-lyase YP_002732490.1 744247 R 546272 CDS YP_002732491.1 225852258 7676917 745627..746394 1 NC_012441.1 bacitracin transport permease BcrC 746394 7676917 BMEA_A0780 Brucella melitensis ATCC 23457 bacitracin transport permease BcrC YP_002732491.1 745627 D 546272 CDS YP_002732492.1 225852259 7676918 746849..747880 1 NC_012441.1 lysine-arginine-ornithine-binding periplasmic protein 747880 7676918 BMEA_A0781 Brucella melitensis ATCC 23457 lysine-arginine-ornithine-binding periplasmic protein YP_002732492.1 746849 D 546272 CDS YP_002732493.1 225852260 7676919 747914..748141 1 NC_012441.1 hypothetical protein 748141 7676919 BMEA_A0782 Brucella melitensis ATCC 23457 hypothetical protein YP_002732493.1 747914 D 546272 CDS YP_002732494.1 225852261 7676920 748177..749370 1 NC_012441.1 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 749370 7676920 BMEA_A0783 Brucella melitensis ATCC 23457 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease YP_002732494.1 748177 D 546272 CDS YP_002732495.1 225852262 7676922 750544..751359 1 NC_012441.1 glutamate/glutamine/aspartate/asparagine transport ATP-binding protein BztD 751359 7676922 BMEA_A0785 Brucella melitensis ATCC 23457 glutamate/glutamine/aspartate/asparagine transport ATP-binding protein BztD YP_002732495.1 750544 D 546272 CDS YP_002732496.1 225852263 7676923 complement(751407..752612) 1 NC_012441.1 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 752612 7676923 BMEA_A0786 Brucella melitensis ATCC 23457 salicylate hydroxylase YP_002732496.1 751407 R 546272 CDS YP_002732497.1 225852264 7676924 complement(752642..752896) 1 NC_012441.1 hypothetical protein 752896 7676924 BMEA_A0787 Brucella melitensis ATCC 23457 hypothetical protein YP_002732497.1 752642 R 546272 CDS YP_002732498.1 225852265 7676925 753182..755422 1 NC_012441.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 755422 7676925 BMEA_A0788 Brucella melitensis ATCC 23457 polyphosphate kinase YP_002732498.1 753182 D 546272 CDS YP_002732499.1 225852266 7676926 755419..756957 1 NC_012441.1 Ppx/GppA phosphatase 756957 7676926 BMEA_A0789 Brucella melitensis ATCC 23457 Ppx/GppA phosphatase YP_002732499.1 755419 D 546272 CDS YP_002732500.1 225852267 7676927 complement(757055..758212) 1 NC_012441.1 ribonuclease D 758212 rnd 7676927 rnd Brucella melitensis ATCC 23457 ribonuclease D YP_002732500.1 757055 R 546272 CDS YP_002732501.1 225852268 7676928 758439..760226 1 NC_012441.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 760226 aspS 7676928 aspS Brucella melitensis ATCC 23457 aspartyl-tRNA synthetase YP_002732501.1 758439 D 546272 CDS YP_002732502.1 225852269 7676929 complement(760267..761463) 1 NC_012441.1 hypothetical protein 761463 7676929 BMEA_A0792 Brucella melitensis ATCC 23457 hypothetical protein YP_002732502.1 760267 R 546272 CDS YP_002732503.1 225852270 7676930 761518..761757 1 NC_012441.1 hypothetical protein 761757 7676930 BMEA_A0793 Brucella melitensis ATCC 23457 hypothetical protein YP_002732503.1 761518 D 546272 CDS YP_002732504.1 225852271 7677883 761863..764175 1 NC_012441.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 764175 parC 7677883 parC Brucella melitensis ATCC 23457 DNA topoisomerase IV subunit A YP_002732504.1 761863 D 546272 CDS YP_002732505.1 225852272 7677884 complement(764354..765103) 1 NC_012441.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 765103 7677884 BMEA_A0795 Brucella melitensis ATCC 23457 arginyl-tRNA-protein transferase YP_002732505.1 764354 R 546272 CDS YP_002732506.1 225852273 7677885 complement(765224..765694) 1 NC_012441.1 RDD domain-containing protein 765694 7677885 BMEA_A0796 Brucella melitensis ATCC 23457 RDD domain-containing protein YP_002732506.1 765224 R 546272 CDS YP_002732507.1 225852274 7677886 complement(765841..766878) 1 NC_012441.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 766878 7677886 BMEA_A0797 Brucella melitensis ATCC 23457 delta-aminolevulinic acid dehydratase YP_002732507.1 765841 R 546272 CDS YP_002732508.1 225852275 7677887 767046..768095 1 NC_012441.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 768095 7677887 BMEA_A0798 Brucella melitensis ATCC 23457 3-hydroxyisobutyryl-CoA hydrolase YP_002732508.1 767046 D 546272 CDS YP_002732509.1 225852276 7677888 768109..768543 1 NC_012441.1 hypothetical protein 768543 7677888 BMEA_A0799 Brucella melitensis ATCC 23457 hypothetical protein YP_002732509.1 768109 D 546272 CDS YP_002732510.1 225852277 7677889 768774..769373 1 NC_012441.1 MarR family transcriptional regulator 769373 7677889 BMEA_A0800 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002732510.1 768774 D 546272 CDS YP_002732511.1 225852278 7677890 complement(769460..769600) 1 NC_012441.1 hypothetical protein 769600 7677890 BMEA_A0801 Brucella melitensis ATCC 23457 hypothetical protein YP_002732511.1 769460 R 546272 CDS YP_002732512.1 225852279 7677891 769735..771036 1 NC_012441.1 peptidoglycan-binding domain 1 protein 771036 7677891 BMEA_A0802 Brucella melitensis ATCC 23457 peptidoglycan-binding domain 1 protein YP_002732512.1 769735 D 546272 CDS YP_002732513.1 225852280 7677892 771129..771263 1 NC_012441.1 hypothetical protein 771263 7677892 BMEA_A0803 Brucella melitensis ATCC 23457 hypothetical protein YP_002732513.1 771129 D 546272 CDS YP_002732514.1 225852281 7677893 771267..772583 1 NC_012441.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 772583 7677893 BMEA_A0804 Brucella melitensis ATCC 23457 serine hydroxymethyltransferase YP_002732514.1 771267 D 546272 CDS YP_002732515.1 225852282 7677894 772840..773316 1 NC_012441.1 transcriptional regulator NrdR 773316 7677894 BMEA_A0805 Brucella melitensis ATCC 23457 transcriptional regulator NrdR YP_002732515.1 772840 D 546272 CDS YP_002732516.1 225852283 7677895 773318..774439 1 NC_012441.1 Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; riboflavin biosynthesis protein RibD 774439 ribD 7677895 ribD Brucella melitensis ATCC 23457 riboflavin biosynthesis protein RibD YP_002732516.1 773318 D 546272 CDS YP_002732517.1 225852284 7677896 774439..775047 1 NC_012441.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 775047 ribE 7677896 ribE Brucella melitensis ATCC 23457 riboflavin synthase subunit alpha YP_002732517.1 774439 D 546272 CDS YP_002732518.1 225852285 7677897 775142..775603 1 NC_012441.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 775603 ribH 7677897 ribH Brucella melitensis ATCC 23457 6,7-dimethyl-8-ribityllumazine synthase YP_002732518.1 775142 D 546272 CDS YP_002732519.1 225852286 7677898 775609..776124 1 NC_012441.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 776124 nusB 7677898 nusB Brucella melitensis ATCC 23457 transcription antitermination protein NusB YP_002732519.1 775609 D 546272 CDS YP_002732520.1 225852287 7677899 776575..778731 1 NC_012441.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 778731 7677899 BMEA_A0810 Brucella melitensis ATCC 23457 membrane-bound proton-translocating pyrophosphatase YP_002732520.1 776575 D 546272 CDS YP_002732521.1 225852288 7677900 complement(778803..779309) 1 NC_012441.1 SmpA/OmlA domain-containing protein 779309 7677900 BMEA_A0811 Brucella melitensis ATCC 23457 SmpA/OmlA domain-containing protein YP_002732521.1 778803 R 546272 CDS YP_002732522.1 225852289 7677901 779411..779965 1 NC_012441.1 ubiquinol-cytochrome C chaperone 779965 7677901 BMEA_A0812 Brucella melitensis ATCC 23457 ubiquinol-cytochrome C chaperone YP_002732522.1 779411 D 546272 CDS YP_002732523.1 225852290 7677902 780085..780642 1 NC_012441.1 hypothetical protein 780642 7677902 BMEA_A0813 Brucella melitensis ATCC 23457 hypothetical protein YP_002732523.1 780085 D 546272 CDS YP_002732524.1 225852291 7677903 780760..781800 1 NC_012441.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 781800 plsX 7677903 plsX Brucella melitensis ATCC 23457 putative glycerol-3-phosphate acyltransferase PlsX YP_002732524.1 780760 D 546272 CDS YP_002732525.1 225852292 7677904 782048..783019 1 NC_012441.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 783019 fabH 7677904 fabH Brucella melitensis ATCC 23457 3-oxoacyl-ACP synthase YP_002732525.1 782048 D 546272 CDS YP_002732526.1 225852293 7677905 783138..783461 1 NC_012441.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 783461 ihfA 7677905 ihfA Brucella melitensis ATCC 23457 integration host factor subunit alpha YP_002732526.1 783138 D 546272 CDS YP_002732527.1 225852294 7677906 783995..784537 1 NC_012441.1 MerR family transcriptional regulator 784537 7677906 BMEA_A0817 Brucella melitensis ATCC 23457 MerR family transcriptional regulator YP_002732527.1 783995 D 546272 CDS YP_002732528.1 225852295 7677907 complement(784587..784904) 1 NC_012441.1 quaternary ammonium compound-resistance protein SugE 784904 7677907 BMEA_A0818 Brucella melitensis ATCC 23457 quaternary ammonium compound-resistance protein SugE YP_002732528.1 784587 R 546272 CDS YP_002732529.1 225852296 7677909 complement(785250..786788) 1 NC_012441.1 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 786788 7677909 BMEA_A0820 Brucella melitensis ATCC 23457 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_002732529.1 785250 R 546272 CDS YP_002732530.1 225852297 7677910 complement(786918..787133) 1 NC_012441.1 group 1 glycosyl transferase 787133 7677910 BMEA_A0821 Brucella melitensis ATCC 23457 group 1 glycosyl transferase YP_002732530.1 786918 R 546272 CDS YP_002732531.1 225852298 7677911 complement(787142..787729) 1 NC_012441.1 polysaccharide export protein 787729 7677911 BMEA_A0822 Brucella melitensis ATCC 23457 polysaccharide export protein YP_002732531.1 787142 R 546272 CDS YP_002732532.1 225852299 7677912 787853..788515 1 NC_012441.1 exopolysaccharide transport protein family protein 788515 7677912 BMEA_A0823 Brucella melitensis ATCC 23457 exopolysaccharide transport protein family protein YP_002732532.1 787853 D 546272 CDS YP_002732533.1 225852300 7677913 complement(788583..788801) 1 NC_012441.1 hypothetical protein 788801 7677913 BMEA_A0824 Brucella melitensis ATCC 23457 hypothetical protein YP_002732533.1 788583 R 546272 CDS YP_002732534.1 225852301 7677914 789153..790229 1 NC_012441.1 cytochrome oxidase assembly 790229 7677914 BMEA_A0825 Brucella melitensis ATCC 23457 cytochrome oxidase assembly YP_002732534.1 789153 D 546272 CDS YP_002732535.1 225852302 7677915 complement(790382..791314) 1 NC_012441.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 791314 argC 7677915 argC Brucella melitensis ATCC 23457 N-acetyl-gamma-glutamyl-phosphate reductase YP_002732535.1 790382 R 546272 CDS YP_002732536.1 225852303 7677916 complement(791404..792354) 1 NC_012441.1 catalyzes the formation of putrescine from agmatine; agmatinase 792354 speB 7677916 speB Brucella melitensis ATCC 23457 agmatinase YP_002732536.1 791404 R 546272 CDS YP_002732537.1 225852304 7677917 complement(792445..792921) 1 NC_012441.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 792921 7677917 BMEA_A0828 Brucella melitensis ATCC 23457 30S ribosomal protein S9 YP_002732537.1 792445 R 546272 CDS YP_002732538.1 225852305 7677918 complement(792924..793388) 1 NC_012441.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 793388 rplM 7677918 rplM Brucella melitensis ATCC 23457 50S ribosomal protein L13 YP_002732538.1 792924 R 546272 CDS YP_002732539.1 225852306 7677919 complement(793624..794070) 1 NC_012441.1 thioesterase superfamily protein 794070 7677919 BMEA_A0830 Brucella melitensis ATCC 23457 thioesterase superfamily protein YP_002732539.1 793624 R 546272 CDS YP_002732540.1 225852307 7677920 794304..795587 1 NC_012441.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 795587 7677920 BMEA_A0831 Brucella melitensis ATCC 23457 O-acetylhomoserine aminocarboxypropyltransferase YP_002732540.1 794304 D 546272 CDS YP_002732541.1 225852308 7677921 complement(795659..796048) 1 NC_012441.1 hypothetical protein 796048 7677921 BMEA_A0832 Brucella melitensis ATCC 23457 hypothetical protein YP_002732541.1 795659 R 546272 CDS YP_002732542.1 225852309 7677922 796288..796419 1 NC_012441.1 hypothetical protein 796419 7677922 BMEA_A0833 Brucella melitensis ATCC 23457 hypothetical protein YP_002732542.1 796288 D 546272 CDS YP_002732543.1 225852310 7677923 796740..797108 1 NC_012441.1 transposase 797108 7677923 BMEA_A0834 Brucella melitensis ATCC 23457 transposase YP_002732543.1 796740 D 546272 CDS YP_002732544.1 225852311 7677924 797105..797497 1 NC_012441.1 IS4 transposase 797497 7677924 BMEA_A0835 Brucella melitensis ATCC 23457 IS4 transposase YP_002732544.1 797105 D 546272 CDS YP_002732545.1 225852312 7677925 797517..798026 1 NC_012441.1 hypothetical protein 798026 7677925 BMEA_A0836 Brucella melitensis ATCC 23457 hypothetical protein YP_002732545.1 797517 D 546272 CDS YP_002732546.1 225852313 7677926 798023..798418 1 NC_012441.1 hypothetical protein 798418 7677926 BMEA_A0837 Brucella melitensis ATCC 23457 hypothetical protein YP_002732546.1 798023 D 546272 CDS YP_002732547.1 225852314 7677927 798472..798807 1 NC_012441.1 hypothetical protein 798807 7677927 BMEA_A0838 Brucella melitensis ATCC 23457 hypothetical protein YP_002732547.1 798472 D 546272 CDS YP_002732548.1 225852315 7677928 complement(798864..799265) 1 NC_012441.1 hypothetical protein 799265 7677928 BMEA_A0839 Brucella melitensis ATCC 23457 hypothetical protein YP_002732548.1 798864 R 546272 CDS YP_002732549.1 225852316 7677930 799562..799744 1 NC_012441.1 hypothetical protein 799744 7677930 BMEA_A0841 Brucella melitensis ATCC 23457 hypothetical protein YP_002732549.1 799562 D 546272 CDS YP_002732550.1 225852317 7677932 complement(800129..800332) 1 NC_012441.1 hypothetical protein 800332 7677932 BMEA_A0843 Brucella melitensis ATCC 23457 hypothetical protein YP_002732550.1 800129 R 546272 CDS YP_002732551.1 225852318 7677933 800840..801205 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 801205 7677933 BMEA_A0844 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit A YP_002732551.1 800840 D 546272 CDS YP_002732552.1 225852319 7677934 801196..801777 1 NC_012441.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 801777 7677934 BMEA_A0845 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit B YP_002732552.1 801196 D 546272 CDS YP_002732553.1 225852320 7677935 801890..802498 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 802498 nuoC 7677935 nuoC Brucella melitensis ATCC 23457 NADH dehydrogenase subunit C YP_002732553.1 801890 D 546272 CDS YP_002732554.1 225852321 7677936 802516..803706 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 803706 nuoD 7677936 nuoD Brucella melitensis ATCC 23457 NADH dehydrogenase subunit D YP_002732554.1 802516 D 546272 CDS YP_002732555.1 225852322 7677937 803706..804419 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 804419 nuoE 7677937 nuoE Brucella melitensis ATCC 23457 NADH dehydrogenase subunit E YP_002732555.1 803706 D 546272 CDS YP_002732556.1 225852323 7677938 804423..805730 1 NC_012441.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 805730 nuoF 7677938 nuoF Brucella melitensis ATCC 23457 NADH dehydrogenase I subunit F YP_002732556.1 804423 D 546272 CDS YP_002732557.1 225852324 7677939 805865..807949 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 807949 7677939 BMEA_A0850 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit G YP_002732557.1 805865 D 546272 CDS YP_002732558.1 225852325 7677940 807969..809012 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 809012 7677940 BMEA_A0851 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit H YP_002732558.1 807969 D 546272 CDS YP_002732559.1 225852326 7677941 809025..809516 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 809516 7677941 BMEA_A0852 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit I YP_002732559.1 809025 D 546272 CDS YP_002732560.1 225852327 7677942 809690..810307 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 810307 7677942 BMEA_A0853 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit J YP_002732560.1 809690 D 546272 CDS YP_002732561.1 225852328 7677943 810318..810626 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 810626 7677943 BMEA_A0854 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit K YP_002732561.1 810318 D 546272 CDS YP_002732562.1 225852329 7677944 810634..812619 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 812619 7677944 BMEA_A0855 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit L YP_002732562.1 810634 D 546272 CDS YP_002732563.1 225852330 7677945 812619..814127 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 814127 7677945 BMEA_A0856 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit M YP_002732563.1 812619 D 546272 CDS YP_002732564.1 225852331 7677946 814149..815585 1 NC_012441.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 815585 7677946 BMEA_A0857 Brucella melitensis ATCC 23457 NADH dehydrogenase subunit N YP_002732564.1 814149 D 546272 CDS YP_002732565.1 225852332 7677947 815611..816408 1 NC_012441.1 biotin--acetyl-CoA-carboxylase ligase 816408 7677947 BMEA_A0858 Brucella melitensis ATCC 23457 biotin--acetyl-CoA-carboxylase ligase YP_002732565.1 815611 D 546272 CDS YP_002732566.1 225852333 7677948 816602..818278 1 NC_012441.1 hypothetical protein 818278 7677948 BMEA_A0859 Brucella melitensis ATCC 23457 hypothetical protein YP_002732566.1 816602 D 546272 CDS YP_002732567.1 225852334 7677949 818318..818722 1 NC_012441.1 methylmalonyl-CoA epimerase 818722 mce 7677949 mce Brucella melitensis ATCC 23457 methylmalonyl-CoA epimerase YP_002732567.1 818318 D 546272 CDS YP_002732568.1 225852335 7677950 818725..818994 1 NC_012441.1 hypothetical protein 818994 7677950 BMEA_A0861 Brucella melitensis ATCC 23457 hypothetical protein YP_002732568.1 818725 D 546272 CDS YP_002732569.1 225852336 7677951 819842..821170 1 NC_012441.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 821170 proS 7677951 proS Brucella melitensis ATCC 23457 prolyl-tRNA synthetase YP_002732569.1 819842 D 546272 CDS YP_002732570.1 225852337 7677952 821212..822480 1 NC_012441.1 lipoprotein releasing system, transmembrane protein, LolC/E family protein 822480 7677952 BMEA_A0863 Brucella melitensis ATCC 23457 lipoprotein releasing system, transmembrane protein, LolC/E family protein YP_002732570.1 821212 D 546272 CDS YP_002732571.1 225852338 7677953 822480..823163 1 NC_012441.1 lipoprotein-releasing system ATP-binding protein lolD 823163 7677953 BMEA_A0864 Brucella melitensis ATCC 23457 lipoprotein-releasing system ATP-binding protein lolD YP_002732571.1 822480 D 546272 CDS YP_002732572.1 225852339 7677954 823822..827313 1 NC_012441.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 827313 dnaE 7677954 dnaE Brucella melitensis ATCC 23457 DNA polymerase III subunit alpha YP_002732572.1 823822 D 546272 CDS YP_002732573.1 225852340 7677955 827354..827551 1 NC_012441.1 hypothetical protein 827551 7677955 BMEA_A0866 Brucella melitensis ATCC 23457 hypothetical protein YP_002732573.1 827354 D 546272 CDS YP_002732574.1 225852341 7677956 complement(827596..828009) 1 NC_012441.1 hypothetical protein 828009 7677956 BMEA_A0867 Brucella melitensis ATCC 23457 hypothetical protein YP_002732574.1 827596 R 546272 CDS YP_002732575.1 225852342 7677957 complement(828281..829303) 1 NC_012441.1 extensin family protein 829303 7677957 BMEA_A0868 Brucella melitensis ATCC 23457 extensin family protein YP_002732575.1 828281 R 546272 CDS YP_002732576.1 225852343 7677958 829587..830204 1 NC_012441.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 830204 rpsD 7677958 rpsD Brucella melitensis ATCC 23457 30S ribosomal protein S4 YP_002732576.1 829587 D 546272 CDS YP_002732577.1 225852344 7677959 830734..831615 1 NC_012441.1 PP-loop domain-containing protein 831615 7677959 BMEA_A0870 Brucella melitensis ATCC 23457 PP-loop domain-containing protein YP_002732577.1 830734 D 546272 CDS YP_002732578.1 225852345 7677960 831602..832429 1 NC_012441.1 inositol monophosphatase family protein 832429 7677960 BMEA_A0871 Brucella melitensis ATCC 23457 inositol monophosphatase family protein YP_002732578.1 831602 D 546272 CDS YP_002732579.1 225852346 7677961 complement(832644..833909) 1 NC_012441.1 drug resistance transporter, Bcr/CflA subfamily protein 833909 7677961 BMEA_A0872 Brucella melitensis ATCC 23457 drug resistance transporter, Bcr/CflA subfamily protein YP_002732579.1 832644 R 546272 CDS YP_002732580.1 225852347 7677962 833908..834093 1 NC_012441.1 hypothetical protein 834093 7677962 BMEA_A0873 Brucella melitensis ATCC 23457 hypothetical protein YP_002732580.1 833908 D 546272 CDS YP_002732581.1 225852348 7677963 complement(834180..834512) 1 NC_012441.1 glutaredoxin-like protein 834512 7677963 BMEA_A0874 Brucella melitensis ATCC 23457 glutaredoxin-like protein YP_002732581.1 834180 R 546272 CDS YP_002732582.1 225852349 7677640 complement(834697..834930) 1 NC_012441.1 hypothetical protein 834930 7677640 BMEA_A0875 Brucella melitensis ATCC 23457 hypothetical protein YP_002732582.1 834697 R 546272 CDS YP_002732583.1 225852350 7677641 complement(835200..837422) 1 NC_012441.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 837422 purL 7677641 purL Brucella melitensis ATCC 23457 phosphoribosylformylglycinamidine synthase II YP_002732583.1 835200 R 546272 CDS YP_002732584.1 225852351 7677642 complement(837609..838010) 1 NC_012441.1 hypothetical protein 838010 7677642 BMEA_A0877 Brucella melitensis ATCC 23457 hypothetical protein YP_002732584.1 837609 R 546272 CDS YP_002732585.1 225852352 7677643 complement(838070..838717) 1 NC_012441.1 glutathione S-transferase domain-containing protein 838717 7677643 BMEA_A0878 Brucella melitensis ATCC 23457 glutathione S-transferase domain-containing protein YP_002732585.1 838070 R 546272 CDS YP_002732586.1 225852353 7677644 complement(838969..839640) 1 NC_012441.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 839640 purQ 7677644 purQ Brucella melitensis ATCC 23457 phosphoribosylformylglycinamidine synthase I YP_002732586.1 838969 R 546272 CDS YP_002732587.1 225852354 7677645 complement(839663..839905) 1 NC_012441.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 839905 purS 7677645 purS Brucella melitensis ATCC 23457 phosphoribosylformylglycinamidine synthase subunit PurS YP_002732587.1 839663 R 546272 CDS YP_002732588.1 225852355 7677646 complement(840021..840785) 1 NC_012441.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 840785 purC 7677646 purC Brucella melitensis ATCC 23457 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002732588.1 840021 R 546272 CDS YP_002732589.1 225852356 7677647 841041..841364 1 NC_012441.1 hypothetical protein 841364 7677647 BMEA_A0882 Brucella melitensis ATCC 23457 hypothetical protein YP_002732589.1 841041 D 546272 CDS YP_002732590.1 225852357 7677648 841429..842196 1 NC_012441.1 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 842196 7677648 BMEA_A0883 Brucella melitensis ATCC 23457 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_002732590.1 841429 D 546272 CDS YP_002732591.1 225852358 7677649 complement(842245..842811) 1 NC_012441.1 hypothetical protein 842811 7677649 BMEA_A0884 Brucella melitensis ATCC 23457 hypothetical protein YP_002732591.1 842245 R 546272 CDS YP_002732592.1 225852359 7677650 842834..842935 1 NC_012441.1 hypothetical protein 842935 7677650 BMEA_A0885 Brucella melitensis ATCC 23457 hypothetical protein YP_002732592.1 842834 D 546272 CDS YP_002732593.1 225852360 7677651 843080..843955 1 NC_012441.1 biphenyl-2,3-diol 1,2-dioxygenase 3 843955 7677651 BMEA_A0886 Brucella melitensis ATCC 23457 biphenyl-2,3-diol 1,2-dioxygenase 3 YP_002732593.1 843080 D 546272 CDS YP_002732594.1 225852361 7677652 complement(844181..845482) 1 NC_012441.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 845482 purB 7677652 purB Brucella melitensis ATCC 23457 adenylosuccinate lyase YP_002732594.1 844181 R 546272 CDS YP_002732595.1 225852362 7677653 complement(845509..846186) 1 NC_012441.1 ribulose-phosphate 3-epimerase 846186 rpe 7677653 rpe Brucella melitensis ATCC 23457 ribulose-phosphate 3-epimerase YP_002732595.1 845509 R 546272 CDS YP_002732596.1 225852363 7677654 complement(846344..847270) 1 NC_012441.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 847270 7677654 BMEA_A0889 Brucella melitensis ATCC 23457 lipid A biosynthesis lauroyl acyltransferase YP_002732596.1 846344 R 546272 CDS YP_002732597.1 225852364 7677655 complement(847284..848312) 1 NC_012441.1 hypothetical protein 848312 7677655 BMEA_A0890 Brucella melitensis ATCC 23457 hypothetical protein YP_002732597.1 847284 R 546272 CDS YP_002732598.1 225852365 7677656 complement(848394..849671) 1 NC_012441.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-(acyl carrier protein) synthase II 849671 7677656 BMEA_A0891 Brucella melitensis ATCC 23457 3-oxoacyl-(acyl carrier protein) synthase II YP_002732598.1 848394 R 546272 CDS YP_002732599.1 225852366 7677657 complement(849673..850854) 1 NC_012441.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 850854 7677657 BMEA_A0892 Brucella melitensis ATCC 23457 3-oxoacyl-(acyl carrier protein) synthase II YP_002732599.1 849673 R 546272 CDS YP_002732600.1 225852367 7677658 complement(851002..851283) 1 NC_012441.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein 851283 7677658 BMEA_A0893 Brucella melitensis ATCC 23457 acyl carrier protein YP_002732600.1 851002 R 546272 CDS YP_002732601.1 225852368 7677659 complement(851484..852245) 1 NC_012441.1 hypothetical protein 852245 7677659 BMEA_A0894 Brucella melitensis ATCC 23457 hypothetical protein YP_002732601.1 851484 R 546272 CDS YP_002732602.1 225852369 7677660 852461..853483 1 NC_012441.1 aldose 1-epimerase 853483 7677660 BMEA_A0895 Brucella melitensis ATCC 23457 aldose 1-epimerase YP_002732602.1 852461 D 546272 CDS YP_002732603.1 225852370 7677661 complement(853480..854397) 1 NC_012441.1 2-dehydro-3-deoxygluconokinase 854397 7677661 BMEA_A0896 Brucella melitensis ATCC 23457 2-dehydro-3-deoxygluconokinase YP_002732603.1 853480 R 546272 CDS YP_002732604.1 225852371 7677662 854586..855317 1 NC_012441.1 phosphonate metabolism protein 855317 7677662 BMEA_A0897 Brucella melitensis ATCC 23457 phosphonate metabolism protein YP_002732604.1 854586 D 546272 CDS YP_002732605.1 225852372 7677663 855321..856460 1 NC_012441.1 phosphonate metabolism protein PhnM 856460 phnM 7677663 phnM Brucella melitensis ATCC 23457 phosphonate metabolism protein PhnM YP_002732605.1 855321 D 546272 CDS YP_002732606.1 225852373 7677664 complement(856457..857140) 1 NC_012441.1 HAD-superfamily hydrolase 857140 7677664 BMEA_A0899 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002732606.1 856457 R 546272 CDS YP_002732607.1 225852374 7677665 857397..858185 1 NC_012441.1 family 3 extracellular solute-binding protein 858185 7677665 BMEA_A0900 Brucella melitensis ATCC 23457 family 3 extracellular solute-binding protein YP_002732607.1 857397 D 546272 CDS YP_002732608.1 225852375 7677666 858377..859399 1 NC_012441.1 tRNA-dihydrouridine synthase A 859399 7677666 BMEA_A0901 Brucella melitensis ATCC 23457 tRNA-dihydrouridine synthase A YP_002732608.1 858377 D 546272 CDS YP_002732609.1 225852376 7677667 complement(859396..860100) 1 NC_012441.1 hypothetical protein 860100 7677667 BMEA_A0902 Brucella melitensis ATCC 23457 hypothetical protein YP_002732609.1 859396 R 546272 CDS YP_002732610.1 225852377 7677668 complement(860100..860249) 1 NC_012441.1 hypothetical protein 860249 7677668 BMEA_A0903 Brucella melitensis ATCC 23457 hypothetical protein YP_002732610.1 860100 R 546272 CDS YP_002732611.1 225852378 7677669 complement(860314..861096) 1 NC_012441.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 861096 cobS 7677669 cobS Brucella melitensis ATCC 23457 cobalamin synthase YP_002732611.1 860314 R 546272 CDS YP_002732612.1 225852379 7677670 861250..862269 1 NC_012441.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 862269 cobT 7677670 cobT Brucella melitensis ATCC 23457 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_002732612.1 861250 D 546272 CDS YP_002732613.1 225852380 7677671 complement(862377..862856) 1 NC_012441.1 hypothetical protein 862856 7677671 BMEA_A0906 Brucella melitensis ATCC 23457 hypothetical protein YP_002732613.1 862377 R 546272 CDS YP_002732614.1 225852381 7677672 complement(862985..863626) 1 NC_012441.1 hypothetical protein 863626 7677672 BMEA_A0907 Brucella melitensis ATCC 23457 hypothetical protein YP_002732614.1 862985 R 546272 CDS YP_002732615.1 225852382 7677673 complement(863723..864292) 1 NC_012441.1 nuclease, SNase domain-containing protein 864292 7677673 BMEA_A0908 Brucella melitensis ATCC 23457 nuclease, SNase domain-containing protein YP_002732615.1 863723 R 546272 CDS YP_002732616.1 225852383 7677674 864263..864541 1 NC_012441.1 hypothetical protein 864541 7677674 BMEA_A0909 Brucella melitensis ATCC 23457 hypothetical protein YP_002732616.1 864263 D 546272 CDS YP_002732617.1 225852384 7677675 864913..865716 1 NC_012441.1 exopolysaccharide production negative regulator 865716 7677675 BMEA_A0910 Brucella melitensis ATCC 23457 exopolysaccharide production negative regulator YP_002732617.1 864913 D 546272 CDS YP_002732618.1 225852385 7677676 complement(865775..866557) 1 NC_012441.1 exodeoxyribonuclease III Xth 866557 7677676 BMEA_A0911 Brucella melitensis ATCC 23457 exodeoxyribonuclease III Xth YP_002732618.1 865775 R 546272 CDS YP_002732619.1 225852386 7677677 866726..867433 1 NC_012441.1 hypothetical protein 867433 7677677 BMEA_A0912 Brucella melitensis ATCC 23457 hypothetical protein YP_002732619.1 866726 D 546272 CDS YP_002732620.1 225852387 7677678 complement(867514..867840) 1 NC_012441.1 iron-sulfur cluster assembly accessory protein 867840 7677678 BMEA_A0913 Brucella melitensis ATCC 23457 iron-sulfur cluster assembly accessory protein YP_002732620.1 867514 R 546272 CDS YP_002732621.1 225852388 7677679 868007..869215 1 NC_012441.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 869215 dgt 7677679 dgt Brucella melitensis ATCC 23457 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_002732621.1 868007 D 546272 CDS YP_002732622.1 225852389 7677680 869437..871194 1 NC_012441.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 871194 argS 7677680 argS Brucella melitensis ATCC 23457 arginyl-tRNA synthetase YP_002732622.1 869437 D 546272 CDS YP_002732623.1 225852390 7677681 871406..874378 1 NC_012441.1 oleosin-B6 874378 7677681 BMEA_A0916 Brucella melitensis ATCC 23457 oleosin-B6 YP_002732623.1 871406 D 546272 CDS YP_002732624.1 225852391 7677682 874579..875598 1 NC_012441.1 beta-hexosaminidase A 875598 7677682 BMEA_A0917 Brucella melitensis ATCC 23457 beta-hexosaminidase A YP_002732624.1 874579 D 546272 CDS YP_002732625.1 225852392 7677683 875671..876522 1 NC_012441.1 chromosome segregation and condensation protein ScpA 876522 7677683 BMEA_A0918 Brucella melitensis ATCC 23457 chromosome segregation and condensation protein ScpA YP_002732625.1 875671 D 546272 CDS YP_002732626.1 225852393 7677684 876515..877240 1 NC_012441.1 segregation and condensation protein B 877240 scpB 7677684 scpB Brucella melitensis ATCC 23457 segregation and condensation protein B YP_002732626.1 876515 D 546272 CDS YP_002732627.1 225852394 7677685 877386..877604 1 NC_012441.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 877604 tatA 7677685 tatA Brucella melitensis ATCC 23457 twin arginine translocase protein A YP_002732627.1 877386 D 546272 CDS YP_002732628.1 225852395 7677686 877685..878281 1 NC_012441.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 878281 tatB 7677686 tatB Brucella melitensis ATCC 23457 sec-independent translocase YP_002732628.1 877685 D 546272 CDS YP_002732629.1 225852396 7677687 878278..879102 1 NC_012441.1 Sec-independent protein translocase TatC 879102 tatC 7677687 tatC Brucella melitensis ATCC 23457 Sec-independent protein translocase TatC YP_002732629.1 878278 D 546272 CDS YP_002732630.1 225852397 7677688 879179..880462 1 NC_012441.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 880462 serS 7677688 serS Brucella melitensis ATCC 23457 seryl-tRNA synthetase YP_002732630.1 879179 D 546272 CDS YP_002732631.1 225852398 7677689 880611..881378 1 NC_012441.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 881378 surE 7677689 surE Brucella melitensis ATCC 23457 stationary phase survival protein SurE YP_002732631.1 880611 D 546272 CDS YP_002732632.1 225852399 7677690 881375..882043 1 NC_012441.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 882043 7677690 BMEA_A0925 Brucella melitensis ATCC 23457 protein-L-isoaspartate O-methyltransferase YP_002732632.1 881375 D 546272 CDS YP_002732633.1 225852400 7677691 882188..882373 1 NC_012441.1 hypothetical protein 882373 7677691 BMEA_A0926 Brucella melitensis ATCC 23457 hypothetical protein YP_002732633.1 882188 D 546272 CDS YP_002732634.1 225852401 7677692 882422..883720 1 NC_012441.1 peptidase M23B 883720 7677692 BMEA_A0927 Brucella melitensis ATCC 23457 peptidase M23B YP_002732634.1 882422 D 546272 CDS YP_002732635.1 225852402 7677693 complement(883769..884635) 1 NC_012441.1 hypothetical protein 884635 7677693 BMEA_A0928 Brucella melitensis ATCC 23457 hypothetical protein YP_002732635.1 883769 R 546272 CDS YP_002732636.1 225852403 7677694 884795..885136 1 NC_012441.1 preprotein translocase subunit YajC 885136 yajC 7677694 yajC Brucella melitensis ATCC 23457 preprotein translocase subunit YajC YP_002732636.1 884795 D 546272 CDS YP_002732637.1 225852404 7677695 885255..887582 1 NC_012441.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 887582 secD 7677695 secD Brucella melitensis ATCC 23457 bifunctional preprotein translocase subunit SecD/SecF YP_002732637.1 885255 D 546272 CDS YP_002732638.1 225852405 7677696 887585..887974 1 NC_012441.1 hypothetical protein 887974 7677696 BMEA_A0931 Brucella melitensis ATCC 23457 hypothetical protein YP_002732638.1 887585 D 546272 CDS YP_002732639.1 225852406 7677697 887980..888813 1 NC_012441.1 phytoene synthase 888813 7677697 BMEA_A0932 Brucella melitensis ATCC 23457 phytoene synthase YP_002732639.1 887980 D 546272 CDS YP_002732640.1 225852407 7677698 complement(888865..890265) 1 NC_012441.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 890265 gid 7677698 gid Brucella melitensis ATCC 23457 tRNA (uracil-5-)-methyltransferase Gid YP_002732640.1 888865 R 546272 CDS YP_002732641.1 225852408 7677699 complement(890507..890653) 1 NC_012441.1 hypothetical protein 890653 7677699 BMEA_A0934 Brucella melitensis ATCC 23457 hypothetical protein YP_002732641.1 890507 R 546272 CDS YP_002732642.1 225852409 7677700 890927..892063 1 NC_012441.1 hypothetical protein 892063 7677700 BMEA_A0935 Brucella melitensis ATCC 23457 hypothetical protein YP_002732642.1 890927 D 546272 CDS YP_002732643.1 225852410 7677701 892060..892629 1 NC_012441.1 hypothetical protein 892629 7677701 BMEA_A0936 Brucella melitensis ATCC 23457 hypothetical protein YP_002732643.1 892060 D 546272 CDS YP_002732644.1 225852411 7677703 893009..894466 1 NC_012441.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 894466 tig 7677703 tig Brucella melitensis ATCC 23457 trigger factor YP_002732644.1 893009 D 546272 CDS YP_002732645.1 225852412 7677704 894616..896118 1 NC_012441.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 896118 gatB 7677704 gatB Brucella melitensis ATCC 23457 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002732645.1 894616 D 546272 CDS YP_002732646.1 225852413 7677705 896118..896621 1 NC_012441.1 N-acetyltransferase GCN5 896621 7677705 BMEA_A0940 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002732646.1 896118 D 546272 CDS YP_002732647.1 225852414 7677706 896781..897191 1 NC_012441.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 897191 7677706 BMEA_A0941 Brucella melitensis ATCC 23457 NADH dehydrogenase YP_002732647.1 896781 D 546272 CDS YP_002732648.1 225852415 7677707 897251..897376 1 NC_012441.1 hypothetical protein 897376 7677707 BMEA_A0942 Brucella melitensis ATCC 23457 hypothetical protein YP_002732648.1 897251 D 546272 CDS YP_002732649.1 225852416 7677708 897385..897855 1 NC_012441.1 hypothetical protein 897855 7677708 BMEA_A0943 Brucella melitensis ATCC 23457 hypothetical protein YP_002732649.1 897385 D 546272 CDS YP_002732650.1 225852417 7677709 complement(897899..898513) 1 NC_012441.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 898513 aat 7677709 aat Brucella melitensis ATCC 23457 leucyl/phenylalanyl-tRNA--protein transferase YP_002732650.1 897899 R 546272 CDS YP_002732651.1 225852418 7677710 complement(898519..899877) 1 NC_012441.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 899877 accC 7677710 accC Brucella melitensis ATCC 23457 acetyl-CoA carboxylase biotin carboxylase subunit YP_002732651.1 898519 R 546272 CDS YP_002732652.1 225852419 7677711 complement(899927..900397) 1 NC_012441.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 900397 accB 7677711 accB Brucella melitensis ATCC 23457 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002732652.1 899927 R 546272 CDS YP_002732653.1 225852420 7677712 complement(900399..900872) 1 NC_012441.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 900872 aroQ 7677712 aroQ Brucella melitensis ATCC 23457 3-dehydroquinate dehydratase YP_002732653.1 900399 R 546272 CDS YP_002732654.1 225852421 7677713 complement(901116..901913) 1 NC_012441.1 DSBA oxidoreductase 901913 7677713 BMEA_A0948 Brucella melitensis ATCC 23457 DSBA oxidoreductase YP_002732654.1 901116 R 546272 CDS YP_002732655.1 225852422 7677714 complement(901961..903376) 1 NC_012441.1 peptidase M48 Ste24p 903376 7677714 BMEA_A0949 Brucella melitensis ATCC 23457 peptidase M48 Ste24p YP_002732655.1 901961 R 546272 CDS YP_002732656.1 225852423 7677715 903568..904731 1 NC_012441.1 class I and II aminotransferase 904731 7677715 BMEA_A0950 Brucella melitensis ATCC 23457 class I and II aminotransferase YP_002732656.1 903568 D 546272 CDS YP_002732657.1 225852424 7677716 complement(904850..907525) 1 NC_012441.1 ribonuclease, Rne/Rng family protein 907525 7677716 BMEA_A0951 Brucella melitensis ATCC 23457 ribonuclease, Rne/Rng family protein YP_002732657.1 904850 R 546272 CDS YP_002732658.1 225852425 7677717 907528..907713 1 NC_012441.1 hypothetical protein 907713 7677717 BMEA_A0952 Brucella melitensis ATCC 23457 hypothetical protein YP_002732658.1 907528 D 546272 CDS YP_002732659.1 225852426 7677718 908204..909472 1 NC_012441.1 N-acetylmuramoyl-L-alanine amidase 909472 7677718 BMEA_A0953 Brucella melitensis ATCC 23457 N-acetylmuramoyl-L-alanine amidase YP_002732659.1 908204 D 546272 CDS YP_002732660.1 225852427 7677719 909752..912211 1 NC_012441.1 1A family penicillin-binding protein 912211 7677719 BMEA_A0954 Brucella melitensis ATCC 23457 1A family penicillin-binding protein YP_002732660.1 909752 D 546272 CDS YP_002732661.1 225852428 7677720 complement(912267..912398) 1 NC_012441.1 hypothetical protein 912398 7677720 BMEA_A0955 Brucella melitensis ATCC 23457 hypothetical protein YP_002732661.1 912267 R 546272 CDS YP_002732662.1 225852429 7677017 912515..913480 1 NC_012441.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; peptide chain release factor 2 913480 prfB 7677017 prfB Brucella melitensis ATCC 23457 peptide chain release factor 2 YP_002732662.1 912515 D 546272 CDS YP_002732663.1 225852430 7677251 complement(913539..913703) 1 NC_012441.1 hypothetical protein 913703 7677251 BMEA_A0957 Brucella melitensis ATCC 23457 hypothetical protein YP_002732663.1 913539 R 546272 CDS YP_002732664.1 225852431 7677252 913674..914042 1 NC_012441.1 transposase 914042 7677252 BMEA_A0958 Brucella melitensis ATCC 23457 transposase YP_002732664.1 913674 D 546272 CDS YP_002732665.1 225852432 7677253 914039..914317 1 NC_012441.1 IS6501 transposase 914317 7677253 BMEA_A0959 Brucella melitensis ATCC 23457 IS6501 transposase YP_002732665.1 914039 D 546272 CDS YP_002732666.1 225852433 7677254 complement(914584..914946) 1 NC_012441.1 peptidase M23B 914946 7677254 BMEA_A0960 Brucella melitensis ATCC 23457 peptidase M23B YP_002732666.1 914584 R 546272 CDS YP_002732667.1 225852434 7677255 complement(915117..915944) 1 NC_012441.1 hypothetical protein 915944 7677255 BMEA_A0961 Brucella melitensis ATCC 23457 hypothetical protein YP_002732667.1 915117 R 546272 CDS YP_002732668.1 225852435 7677256 complement(915966..916430) 1 NC_012441.1 alkyl hydroperoxide reductase 916430 7677256 BMEA_A0962 Brucella melitensis ATCC 23457 alkyl hydroperoxide reductase YP_002732668.1 915966 R 546272 CDS YP_002732669.1 225852436 7677257 916675..920115 1 NC_012441.1 hypothetical protein 920115 7677257 BMEA_A0963 Brucella melitensis ATCC 23457 hypothetical protein YP_002732669.1 916675 D 546272 CDS YP_002732670.1 225852437 7677258 complement(920174..921427) 1 NC_012441.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 921427 tyrS 7677258 tyrS Brucella melitensis ATCC 23457 tyrosyl-tRNA synthetase YP_002732670.1 920174 R 546272 CDS YP_002732671.1 225852438 7677259 921543..922664 1 NC_012441.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 922664 7677259 BMEA_A0965 Brucella melitensis ATCC 23457 anhydro-N-acetylmuramic acid kinase YP_002732671.1 921543 D 546272 CDS YP_002732672.1 225852439 7677260 complement(922661..922993) 1 NC_012441.1 quaternary ammonium compound-resistance protein QacF 922993 7677260 BMEA_A0966 Brucella melitensis ATCC 23457 quaternary ammonium compound-resistance protein QacF YP_002732672.1 922661 R 546272 CDS YP_002732673.1 225852440 7677261 complement(923105..923779) 1 NC_012441.1 hypothetical protein 923779 7677261 BMEA_A0967 Brucella melitensis ATCC 23457 hypothetical protein YP_002732673.1 923105 R 546272 CDS YP_002732674.1 225852441 7677262 923983..925161 1 NC_012441.1 cysteine desulfurase 925161 7677262 BMEA_A0968 Brucella melitensis ATCC 23457 cysteine desulfurase YP_002732674.1 923983 D 546272 CDS YP_002732675.1 225852442 7677263 925342..926865 1 NC_012441.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 926865 sufB 7677263 sufB Brucella melitensis ATCC 23457 cysteine desulfurase activator complex subunit SufB YP_002732675.1 925342 D 546272 CDS YP_002732676.1 225852443 7677264 926933..927688 1 NC_012441.1 FeS assembly ATPase SufC 927688 sufC 7677264 sufC Brucella melitensis ATCC 23457 FeS assembly ATPase SufC YP_002732676.1 926933 D 546272 CDS YP_002732677.1 225852444 7677265 927702..928979 1 NC_012441.1 FeS assembly protein SufD 928979 sufD 7677265 sufD Brucella melitensis ATCC 23457 FeS assembly protein SufD YP_002732677.1 927702 D 546272 CDS YP_002732678.1 225852445 7677266 929061..930305 1 NC_012441.1 cysteine desulfurase 930305 sufS 7677266 sufS Brucella melitensis ATCC 23457 cysteine desulfurase YP_002732678.1 929061 D 546272 CDS YP_002732679.1 225852446 7677267 930302..930721 1 NC_012441.1 FeS assembly SUF system protein 930721 7677267 BMEA_A0973 Brucella melitensis ATCC 23457 FeS assembly SUF system protein YP_002732679.1 930302 D 546272 CDS YP_002732680.1 225852447 7677268 complement(930755..931726) 1 NC_012441.1 group 2 family glycosyl transferase 931726 7677268 BMEA_A0974 Brucella melitensis ATCC 23457 group 2 family glycosyl transferase YP_002732680.1 930755 R 546272 CDS YP_002732681.1 225852448 7677270 932153..932926 1 NC_012441.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 932926 7677270 BMEA_A0976 Brucella melitensis ATCC 23457 inorganic polyphosphate/ATP-NAD kinase YP_002732681.1 932153 D 546272 CDS YP_002732682.1 225852449 7677271 933254..934702 1 NC_012441.1 ATP-dependent RNA helicase Dbp2 934702 7677271 BMEA_A0977 Brucella melitensis ATCC 23457 ATP-dependent RNA helicase Dbp2 YP_002732682.1 933254 D 546272 CDS YP_002732683.1 225852450 7677272 complement(934939..935319) 1 NC_012441.1 FeS assembly scaffold SufA 935319 sufA 7677272 sufA Brucella melitensis ATCC 23457 FeS assembly scaffold SufA YP_002732683.1 934939 R 546272 CDS YP_002732684.1 225852451 7677273 935512..936135 1 NC_012441.1 hypothetical protein 936135 7677273 BMEA_A0979 Brucella melitensis ATCC 23457 hypothetical protein YP_002732684.1 935512 D 546272 CDS YP_002732685.1 225852452 7677274 936120..936212 1 NC_012441.1 hypothetical protein 936212 7677274 BMEA_A0980 Brucella melitensis ATCC 23457 hypothetical protein YP_002732685.1 936120 D 546272 CDS YP_002732686.1 225852453 7677275 936216..936416 1 NC_012441.1 heavy metal transport/detoxification protein 936416 7677275 BMEA_A0981 Brucella melitensis ATCC 23457 heavy metal transport/detoxification protein YP_002732686.1 936216 D 546272 CDS YP_002732687.1 225852454 7677277 936745..937413 1 NC_012441.1 protein-L-isoaspartate O-methyltransferase 937413 7677277 BMEA_A0983 Brucella melitensis ATCC 23457 protein-L-isoaspartate O-methyltransferase YP_002732687.1 936745 D 546272 CDS YP_002732688.1 225852455 7677278 937552..938922 1 NC_012441.1 type I secretion outer membrane protein 938922 7677278 BMEA_A0984 Brucella melitensis ATCC 23457 type I secretion outer membrane protein YP_002732688.1 937552 D 546272 CDS YP_002732689.1 225852456 7677279 939172..939903 1 NC_012441.1 hypothetical protein 939903 7677279 BMEA_A0985 Brucella melitensis ATCC 23457 hypothetical protein YP_002732689.1 939172 D 546272 CDS YP_002732690.1 225852457 7677280 940194..942926 1 NC_012441.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 942926 valS 7677280 valS Brucella melitensis ATCC 23457 valyl-tRNA synthetase YP_002732690.1 940194 D 546272 CDS YP_002732691.1 225852458 7677281 943290..943619 1 NC_012441.1 hypothetical protein 943619 7677281 BMEA_A0987 Brucella melitensis ATCC 23457 hypothetical protein YP_002732691.1 943290 D 546272 CDS YP_002732692.1 225852459 7677282 943728..944618 1 NC_012441.1 outer membrane protein E 944618 7677282 BMEA_A0988 Brucella melitensis ATCC 23457 outer membrane protein E YP_002732692.1 943728 D 546272 CDS YP_002732693.1 225852460 7677283 complement(944684..945559) 1 NC_012441.1 6-phosphogluconate dehydrogenase 945559 7677283 BMEA_A0989 Brucella melitensis ATCC 23457 6-phosphogluconate dehydrogenase YP_002732693.1 944684 R 546272 CDS YP_002732694.1 225852461 7677284 complement(946679..947152) 1 NC_012441.1 molybdopterin-guanine dinucleotide biosynthesis protein B 947152 mobB 7677284 mobB Brucella melitensis ATCC 23457 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002732694.1 946679 R 546272 CDS YP_002732695.1 225852462 7677285 complement(947178..947843) 1 NC_012441.1 molybdopterin-guanine dinucleotide biosynthesis protein A 947843 mobA 7677285 mobA Brucella melitensis ATCC 23457 molybdopterin-guanine dinucleotide biosynthesis protein A YP_002732695.1 947178 R 546272 CDS YP_002732696.1 225852463 7677286 complement(948019..949053) 1 NC_012441.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 949053 moaA 7677286 moaA Brucella melitensis ATCC 23457 molybdenum cofactor biosynthesis protein A YP_002732696.1 948019 R 546272 CDS YP_002732697.1 225852464 7677287 949240..949599 1 NC_012441.1 hypothetical protein 949599 7677287 BMEA_A0993 Brucella melitensis ATCC 23457 hypothetical protein YP_002732697.1 949240 D 546272 CDS YP_002732698.1 225852465 7677288 complement(949667..950773) 1 NC_012441.1 monooxygenase FAD-binding 950773 7677288 BMEA_A0994 Brucella melitensis ATCC 23457 monooxygenase FAD-binding YP_002732698.1 949667 R 546272 CDS YP_002732699.1 225852466 7677289 complement(951119..952738) 1 NC_012441.1 Fe-S type, tartrate/fumarate subfamily hydro-lyase subunit alpha 952738 7677289 BMEA_A0995 Brucella melitensis ATCC 23457 Fe-S type, tartrate/fumarate subfamily hydro-lyase subunit alpha YP_002732699.1 951119 R 546272 CDS YP_002732700.1 225852467 7677290 953144..953431 1 NC_012441.1 peptidoglycan-binding domain 1 protein 953431 7677290 BMEA_A0996 Brucella melitensis ATCC 23457 peptidoglycan-binding domain 1 protein YP_002732700.1 953144 D 546272 CDS YP_002732701.1 225852468 7677291 953516..955048 1 NC_012441.1 peptidoglycan-binding domain 1 protein 955048 7677291 BMEA_A0997 Brucella melitensis ATCC 23457 peptidoglycan-binding domain 1 protein YP_002732701.1 953516 D 546272 CDS YP_002732702.1 225852469 7677294 complement(955849..956100) 1 NC_012441.1 transglycosylase-associated protein 956100 7677294 BMEA_A1000 Brucella melitensis ATCC 23457 transglycosylase-associated protein YP_002732702.1 955849 R 546272 CDS YP_002732703.1 225852470 7677295 956255..956416 1 NC_012441.1 hypothetical protein 956416 7677295 BMEA_A1001 Brucella melitensis ATCC 23457 hypothetical protein YP_002732703.1 956255 D 546272 CDS YP_002732704.1 225852471 7677297 complement(956609..957634) 1 NC_012441.1 phage-related integrase 957634 7677297 BMEA_A1003 Brucella melitensis ATCC 23457 phage-related integrase YP_002732704.1 956609 R 546272 CDS YP_002732705.1 225852472 7677298 complement(958039..958242) 1 NC_012441.1 hypothetical protein 958242 7677298 BMEA_A1004 Brucella melitensis ATCC 23457 hypothetical protein YP_002732705.1 958039 R 546272 CDS YP_002732706.1 225852473 7677299 958428..958997 1 NC_012441.1 hypothetical protein 958997 7677299 BMEA_A1005 Brucella melitensis ATCC 23457 hypothetical protein YP_002732706.1 958428 D 546272 CDS YP_002732707.1 225852474 7677300 958994..959224 1 NC_012441.1 hypothetical protein 959224 7677300 BMEA_A1006 Brucella melitensis ATCC 23457 hypothetical protein YP_002732707.1 958994 D 546272 CDS YP_002732708.1 225852475 7677301 959221..959496 1 NC_012441.1 hypothetical protein 959496 7677301 BMEA_A1007 Brucella melitensis ATCC 23457 hypothetical protein YP_002732708.1 959221 D 546272 CDS YP_002732709.1 225852476 7677302 959519..959995 1 NC_012441.1 hypothetical protein 959995 7677302 BMEA_A1008 Brucella melitensis ATCC 23457 hypothetical protein YP_002732709.1 959519 D 546272 CDS YP_002732710.1 225852477 7677303 960341..961051 1 NC_012441.1 porin 961051 7677303 BMEA_A1009 Brucella melitensis ATCC 23457 porin YP_002732710.1 960341 D 546272 CDS YP_002732711.1 225852478 7677304 complement(961399..961569) 1 NC_012441.1 hypothetical protein 961569 7677304 BMEA_A1010 Brucella melitensis ATCC 23457 hypothetical protein YP_002732711.1 961399 R 546272 CDS YP_002732712.1 225852479 7677305 961587..961766 1 NC_012441.1 hypothetical protein 961766 7677305 BMEA_A1011 Brucella melitensis ATCC 23457 hypothetical protein YP_002732712.1 961587 D 546272 CDS YP_002732713.1 225852480 7677306 complement(961917..962231) 1 NC_012441.1 hypothetical protein 962231 7677306 BMEA_A1012 Brucella melitensis ATCC 23457 hypothetical protein YP_002732713.1 961917 R 546272 CDS YP_002732714.1 225852481 7677307 complement(962231..962551) 1 NC_012441.1 hypothetical protein 962551 7677307 BMEA_A1013 Brucella melitensis ATCC 23457 hypothetical protein YP_002732714.1 962231 R 546272 CDS YP_002732715.1 225852482 7677308 962639..963247 1 NC_012441.1 queuine tRNA-ribosyltransferase 963247 7677308 BMEA_A1014 Brucella melitensis ATCC 23457 queuine tRNA-ribosyltransferase YP_002732715.1 962639 D 546272 CDS YP_002732716.1 225852483 7677309 963317..963685 1 NC_012441.1 transposase 963685 7677309 BMEA_A1015 Brucella melitensis ATCC 23457 transposase YP_002732716.1 963317 D 546272 CDS YP_002732717.1 225852484 7677310 963682..963960 1 NC_012441.1 IS6501 transposase 963960 7677310 BMEA_A1016 Brucella melitensis ATCC 23457 IS6501 transposase YP_002732717.1 963682 D 546272 CDS YP_002732718.1 225852485 7677311 964076..964768 1 NC_012441.1 hypothetical protein 964768 7677311 BMEA_A1017 Brucella melitensis ATCC 23457 hypothetical protein YP_002732718.1 964076 D 546272 CDS YP_002732719.1 225852486 7677312 964966..965088 1 NC_012441.1 hypothetical protein 965088 7677312 BMEA_A1018 Brucella melitensis ATCC 23457 hypothetical protein YP_002732719.1 964966 D 546272 CDS YP_002732720.1 225852487 7677314 966957..968189 1 NC_012441.1 hypothetical protein 968189 7677314 BMEA_A1020 Brucella melitensis ATCC 23457 hypothetical protein YP_002732720.1 966957 D 546272 CDS YP_002732721.1 225852488 7677315 968186..969745 1 NC_012441.1 hypothetical protein 969745 7677315 BMEA_A1021 Brucella melitensis ATCC 23457 hypothetical protein YP_002732721.1 968186 D 546272 CDS YP_002732722.1 225852489 7677316 complement(969726..969947) 1 NC_012441.1 hypothetical protein 969947 7677316 BMEA_A1022 Brucella melitensis ATCC 23457 hypothetical protein YP_002732722.1 969726 R 546272 CDS YP_002732723.1 225852490 7677317 970092..970850 1 NC_012441.1 hypothetical protein 970850 7677317 BMEA_A1023 Brucella melitensis ATCC 23457 hypothetical protein YP_002732723.1 970092 D 546272 CDS YP_002732724.1 225852491 7677318 971240..971482 1 NC_012441.1 hypothetical protein 971482 7677318 BMEA_A1025 Brucella melitensis ATCC 23457 hypothetical protein YP_002732724.1 971240 D 546272 CDS YP_002732725.1 225852492 7677319 971584..971685 1 NC_012441.1 hypothetical protein 971685 7677319 BMEA_A1027 Brucella melitensis ATCC 23457 hypothetical protein YP_002732725.1 971584 D 546272 CDS YP_002732726.1 225852493 7677320 971694..971831 1 NC_012441.1 hypothetical protein 971831 7677320 BMEA_A1028 Brucella melitensis ATCC 23457 hypothetical protein YP_002732726.1 971694 D 546272 CDS YP_002732727.1 225852494 7677321 971822..972169 1 NC_012441.1 arsenate reductase 972169 arsC 7677321 arsC Brucella melitensis ATCC 23457 arsenate reductase YP_002732727.1 971822 D 546272 CDS YP_002732728.1 225852495 7677322 972540..973805 1 NC_012441.1 rare lipoprotein A 973805 rlpA 7677322 rlpA Brucella melitensis ATCC 23457 rare lipoprotein A YP_002732728.1 972540 D 546272 CDS YP_002732729.1 225852496 7677323 973916..975106 1 NC_012441.1 serine-type D-Ala-D-Ala carboxypeptidase 975106 7677323 BMEA_A1032 Brucella melitensis ATCC 23457 serine-type D-Ala-D-Ala carboxypeptidase YP_002732729.1 973916 D 546272 CDS YP_002732730.1 225852497 7677324 975188..975832 1 NC_012441.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 975832 tmk 7677324 tmk Brucella melitensis ATCC 23457 thymidylate kinase YP_002732730.1 975188 D 546272 CDS YP_002732731.1 225852498 7677325 975829..976911 1 NC_012441.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 976911 holB 7677325 holB Brucella melitensis ATCC 23457 DNA polymerase III subunit delta' YP_002732731.1 975829 D 546272 CDS YP_002732732.1 225852499 7677326 976931..977080 1 NC_012441.1 hypothetical protein 977080 7677326 BMEA_A1035 Brucella melitensis ATCC 23457 hypothetical protein YP_002732732.1 976931 D 546272 CDS YP_002732733.1 225852500 7677327 977080..978627 1 NC_012441.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 978627 metG 7677327 metG Brucella melitensis ATCC 23457 methionyl-tRNA synthetase YP_002732733.1 977080 D 546272 CDS YP_002732734.1 225852501 7677328 978636..979427 1 NC_012441.1 TatD family hydrolase 979427 7677328 BMEA_A1037 Brucella melitensis ATCC 23457 TatD family hydrolase YP_002732734.1 978636 D 546272 CDS YP_002732735.1 225852502 7677329 979430..980248 1 NC_012441.1 beta-lactamase domain-containing protein 980248 7677329 BMEA_A1038 Brucella melitensis ATCC 23457 beta-lactamase domain-containing protein YP_002732735.1 979430 D 546272 CDS YP_002732736.1 225852503 7677330 complement(980298..982097) 1 NC_012441.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABc transporter 982097 7677330 BMEA_A1039 Brucella melitensis ATCC 23457 cyclic beta-1,2-glucan ABc transporter YP_002732736.1 980298 R 546272 CDS YP_002732737.1 225852504 7676201 982232..982366 1 NC_012441.1 hypothetical protein 982366 7676201 BMEA_A1040 Brucella melitensis ATCC 23457 hypothetical protein YP_002732737.1 982232 D 546272 CDS YP_002732738.1 225852505 7677802 982410..983390 1 NC_012441.1 RluA family pseudouridine synthase 983390 7677802 BMEA_A1041 Brucella melitensis ATCC 23457 RluA family pseudouridine synthase YP_002732738.1 982410 D 546272 CDS YP_002732739.1 225852506 7677803 983393..984316 1 NC_012441.1 hypothetical protein 984316 7677803 BMEA_A1042 Brucella melitensis ATCC 23457 hypothetical protein YP_002732739.1 983393 D 546272 CDS YP_002732740.1 225852507 7677804 984313..984963 1 NC_012441.1 HAD-superfamily hydrolase 984963 7677804 BMEA_A1043 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002732740.1 984313 D 546272 CDS YP_002732741.1 225852508 7677805 985005..985787 1 NC_012441.1 ATPase 985787 7677805 BMEA_A1044 Brucella melitensis ATCC 23457 ATPase YP_002732741.1 985005 D 546272 CDS YP_002732742.1 225852509 7677806 complement(985913..987322) 1 NC_012441.1 glutamine synthetase, type I 987322 glnA 7677806 glnA Brucella melitensis ATCC 23457 glutamine synthetase, type I YP_002732742.1 985913 R 546272 CDS YP_002732743.1 225852510 7677807 complement(987470..987808) 1 NC_012441.1 nitrogen regulatory protein P-II 987808 7677807 BMEA_A1046 Brucella melitensis ATCC 23457 nitrogen regulatory protein P-II YP_002732743.1 987470 R 546272 CDS YP_002732744.1 225852511 7677808 988115..989620 1 NC_012441.1 YjeF family protein 989620 7677808 BMEA_A1047 Brucella melitensis ATCC 23457 YjeF family protein YP_002732744.1 988115 D 546272 CDS YP_002732745.1 225852512 7677809 complement(989651..989842) 1 NC_012441.1 hypothetical protein 989842 7677809 BMEA_A1048 Brucella melitensis ATCC 23457 hypothetical protein YP_002732745.1 989651 R 546272 CDS YP_002732746.1 225852513 7677810 complement(989920..990624) 1 NC_012441.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 990624 gph 7677810 gph Brucella melitensis ATCC 23457 phosphoglycolate phosphatase YP_002732746.1 989920 R 546272 CDS YP_002732747.1 225852514 7677811 990679..990792 1 NC_012441.1 hypothetical protein 990792 7677811 BMEA_A1050 Brucella melitensis ATCC 23457 hypothetical protein YP_002732747.1 990679 D 546272 CDS YP_002732748.1 225852515 7677812 990971..991669 1 NC_012441.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 991669 rpiA 7677812 rpiA Brucella melitensis ATCC 23457 ribose-5-phosphate isomerase A YP_002732748.1 990971 D 546272 CDS YP_002732749.1 225852516 7677813 991695..992231 1 NC_012441.1 hypothetical protein 992231 7677813 BMEA_A1052 Brucella melitensis ATCC 23457 hypothetical protein YP_002732749.1 991695 D 546272 CDS YP_002732750.1 225852517 7677814 992385..993779 1 NC_012441.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 993779 gor 7677814 gor Brucella melitensis ATCC 23457 glutathione reductase YP_002732750.1 992385 D 546272 CDS YP_002732751.1 225852518 7677815 993988..995367 1 NC_012441.1 3-deoxy-7-phosphoheptulonate synthase 995367 7677815 BMEA_A1054 Brucella melitensis ATCC 23457 3-deoxy-7-phosphoheptulonate synthase YP_002732751.1 993988 D 546272 CDS YP_002732752.1 225852519 7677816 995481..995831 1 NC_012441.1 diacylglycerol kinase 995831 7677816 BMEA_A1055 Brucella melitensis ATCC 23457 diacylglycerol kinase YP_002732752.1 995481 D 546272 CDS YP_002732753.1 225852520 7677817 995896..997575 1 NC_012441.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 997575 nadE 7677817 nadE Brucella melitensis ATCC 23457 NAD synthetase YP_002732753.1 995896 D 546272 CDS YP_002732754.1 225852521 7677818 997587..998960 1 NC_012441.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 998960 gltX 7677818 gltX Brucella melitensis ATCC 23457 glutamyl-tRNA synthetase YP_002732754.1 997587 D 546272 CDS YP_002732755.1 225852522 7677819 complement(999774..1002098) 1 NC_012441.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 1002098 7677819 BMEA_A1058 Brucella melitensis ATCC 23457 malic enzyme YP_002732755.1 999774 R 546272 CDS YP_002732756.1 225852523 7677820 complement(1002316..1003296) 1 NC_012441.1 mandelate racemase/muconate lactonizing protein 1003296 7677820 BMEA_A1059 Brucella melitensis ATCC 23457 mandelate racemase/muconate lactonizing protein YP_002732756.1 1002316 R 546272 CDS YP_002732757.1 225852524 7677821 1003357..1004532 1 NC_012441.1 hypothetical protein 1004532 7677821 BMEA_A1060 Brucella melitensis ATCC 23457 hypothetical protein YP_002732757.1 1003357 D 546272 CDS YP_002732758.1 225852525 7677822 1004748..1005605 1 NC_012441.1 ABC transporter 1005605 7677822 BMEA_A1061 Brucella melitensis ATCC 23457 ABC transporter YP_002732758.1 1004748 D 546272 CDS YP_002732759.1 225852526 7677823 1005609..1006604 1 NC_012441.1 mammalian cell entry related domain-containing protein 1006604 7677823 BMEA_A1062 Brucella melitensis ATCC 23457 mammalian cell entry related domain-containing protein YP_002732759.1 1005609 D 546272 CDS YP_002732760.1 225852527 7677824 1006628..1007230 1 NC_012441.1 hypothetical protein 1007230 7677824 BMEA_A1063 Brucella melitensis ATCC 23457 hypothetical protein YP_002732760.1 1006628 D 546272 CDS YP_002732761.1 225852528 7677825 complement(1007470..1012143) 1 NC_012441.1 hypothetical protein 1012143 7677825 BMEA_A1064 Brucella melitensis ATCC 23457 hypothetical protein YP_002732761.1 1007470 R 546272 CDS YP_002732762.1 225852529 7677826 1012358..1012639 1 NC_012441.1 hypothetical protein 1012639 7677826 BMEA_A1065 Brucella melitensis ATCC 23457 hypothetical protein YP_002732762.1 1012358 D 546272 CDS YP_002732763.1 225852530 7677827 1012758..1013081 1 NC_012441.1 ferredoxin 1013081 7677827 BMEA_A1066 Brucella melitensis ATCC 23457 ferredoxin YP_002732763.1 1012758 D 546272 CDS YP_002732764.1 225852531 7677828 1013399..1013722 1 NC_012441.1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1013722 7677828 BMEA_A1067 Brucella melitensis ATCC 23457 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002732764.1 1013399 D 546272 CDS YP_002732765.1 225852532 7677829 complement(1013727..1014347) 1 NC_012441.1 hypothetical protein 1014347 7677829 BMEA_A1068 Brucella melitensis ATCC 23457 hypothetical protein YP_002732765.1 1013727 R 546272 CDS YP_002732766.1 225852533 7677830 1014505..1015344 1 NC_012441.1 dihydropteroate synthase 1015344 folP 7677830 folP Brucella melitensis ATCC 23457 dihydropteroate synthase YP_002732766.1 1014505 D 546272 CDS YP_002732767.1 225852534 7677831 1015363..1015722 1 NC_012441.1 dihydroneopterin aldolase 1015722 folB 7677831 folB Brucella melitensis ATCC 23457 dihydroneopterin aldolase YP_002732767.1 1015363 D 546272 CDS YP_002732768.1 225852535 7677832 1015719..1016252 1 NC_012441.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1016252 folK 7677832 folK Brucella melitensis ATCC 23457 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002732768.1 1015719 D 546272 CDS YP_002732769.1 225852536 7677833 complement(1016367..1016924) 1 NC_012441.1 hypothetical protein 1016924 7677833 BMEA_A1073 Brucella melitensis ATCC 23457 hypothetical protein YP_002732769.1 1016367 R 546272 CDS YP_002732770.1 225852537 7677834 complement(1017176..1018249) 1 NC_012441.1 hypothetical protein 1018249 7677834 BMEA_A1074 Brucella melitensis ATCC 23457 hypothetical protein YP_002732770.1 1017176 R 546272 CDS YP_002732771.1 225852538 7677835 complement(1018266..1019705) 1 NC_012441.1 hypothetical protein 1019705 7677835 BMEA_A1075 Brucella melitensis ATCC 23457 hypothetical protein YP_002732771.1 1018266 R 546272 CDS YP_002732772.1 225852539 7677836 complement(1019798..1020298) 1 NC_012441.1 phosphohistidine phosphatase SixA 1020298 7677836 BMEA_A1076 Brucella melitensis ATCC 23457 phosphohistidine phosphatase SixA YP_002732772.1 1019798 R 546272 CDS YP_002732773.1 225852540 7677837 1020695..1021111 1 NC_012441.1 RNA polymerase-binding protein DksA 1021111 dksA 7677837 dksA Brucella melitensis ATCC 23457 RNA polymerase-binding protein DksA YP_002732773.1 1020695 D 546272 CDS YP_002732774.1 225852541 7677838 complement(1021257..1022513) 1 NC_012441.1 hypothetical protein 1022513 7677838 BMEA_A1078 Brucella melitensis ATCC 23457 hypothetical protein YP_002732774.1 1021257 R 546272 CDS YP_002732775.1 225852542 7677839 1022880..1025576 1 NC_012441.1 PAS domain S-box-containing protein 1025576 7677839 BMEA_A1079 Brucella melitensis ATCC 23457 PAS domain S-box-containing protein YP_002732775.1 1022880 D 546272 CDS YP_002732776.1 225852543 7677840 1025601..1026809 1 NC_012441.1 hypothetical protein 1026809 7677840 BMEA_A1080 Brucella melitensis ATCC 23457 hypothetical protein YP_002732776.1 1025601 D 546272 CDS YP_002732777.1 225852544 7677841 1026840..1028162 1 NC_012441.1 beta-lactamase 1028162 7677841 BMEA_A1081 Brucella melitensis ATCC 23457 beta-lactamase YP_002732777.1 1026840 D 546272 CDS YP_002732778.1 225852545 7677842 complement(1028143..1029369) 1 NC_012441.1 mechanosensitive ion channel protein MscS 1029369 7677842 BMEA_A1082 Brucella melitensis ATCC 23457 mechanosensitive ion channel protein MscS YP_002732778.1 1028143 R 546272 CDS YP_002732779.1 225852546 7677843 complement(1029459..1033253) 1 NC_012441.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1033253 7677843 BMEA_A1083 Brucella melitensis ATCC 23457 ribonucleotide-diphosphate reductase subunit alpha YP_002732779.1 1029459 R 546272 CDS YP_002732780.1 225852547 7677844 1033306..1033545 1 NC_012441.1 hypothetical protein 1033545 7677844 BMEA_A1084 Brucella melitensis ATCC 23457 hypothetical protein YP_002732780.1 1033306 D 546272 CDS YP_002732781.1 225852548 7677845 complement(1033955..1034443) 1 NC_012441.1 diphosphoinositol polyphosphate phosphohydrolase 3 beta 1034443 7677845 BMEA_A1085 Brucella melitensis ATCC 23457 diphosphoinositol polyphosphate phosphohydrolase 3 beta YP_002732781.1 1033955 R 546272 CDS YP_002732782.1 225852549 7677846 complement(1034539..1034673) 1 NC_012441.1 hypothetical protein 1034673 7677846 BMEA_A1086 Brucella melitensis ATCC 23457 hypothetical protein YP_002732782.1 1034539 R 546272 CDS YP_002732783.1 225852550 7677847 complement(1035571..1036416) 1 NC_012441.1 UspA domain-containing protein 1036416 7677847 BMEA_A1087 Brucella melitensis ATCC 23457 UspA domain-containing protein YP_002732783.1 1035571 R 546272 CDS YP_002732784.1 225852551 7677848 complement(1036494..1037252) 1 NC_012441.1 CinA-like protein 1037252 7677848 BMEA_A1088 Brucella melitensis ATCC 23457 CinA-like protein YP_002732784.1 1036494 R 546272 CDS YP_002732785.1 225852552 7677849 1037413..1038012 1 NC_012441.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1038012 wrbA 7677849 wrbA Brucella melitensis ATCC 23457 TrpR binding protein WrbA YP_002732785.1 1037413 D 546272 CDS YP_002732786.1 225852553 7677850 complement(1037990..1038139) 1 NC_012441.1 hypothetical protein 1038139 7677850 BMEA_A1090 Brucella melitensis ATCC 23457 hypothetical protein YP_002732786.1 1037990 R 546272 CDS YP_002732787.1 225852554 7677852 1038314..1039573 1 NC_012441.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1039573 ilvA 7677852 ilvA Brucella melitensis ATCC 23457 threonine dehydratase YP_002732787.1 1038314 D 546272 CDS YP_002732788.1 225852555 7677853 1039640..1041247 1 NC_012441.1 DEAD/DEAH box helicase 1041247 7677853 BMEA_A1093 Brucella melitensis ATCC 23457 DEAD/DEAH box helicase YP_002732788.1 1039640 D 546272 CDS YP_002732789.1 225852556 7677854 1041418..1042446 1 NC_012441.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1042446 7677854 BMEA_A1094 Brucella melitensis ATCC 23457 cysteine synthase A YP_002732789.1 1041418 D 546272 CDS YP_002732790.1 225852557 7677855 1042449..1043192 1 NC_012441.1 alanyl-tRNA synthetase 1043192 7677855 BMEA_A1095 Brucella melitensis ATCC 23457 alanyl-tRNA synthetase YP_002732790.1 1042449 D 546272 CDS YP_002732791.1 225852558 7677856 1043219..1044073 1 NC_012441.1 3-mercaptopyruvate sulfurtransferase 1044073 7677856 BMEA_A1096 Brucella melitensis ATCC 23457 3-mercaptopyruvate sulfurtransferase YP_002732791.1 1043219 D 546272 CDS YP_002732792.1 225852559 7677857 1044075..1044596 1 NC_012441.1 N-acetyltransferase GCN5 1044596 7677857 BMEA_A1097 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002732792.1 1044075 D 546272 CDS YP_002732793.1 225852560 7677858 complement(1044635..1045429) 1 NC_012441.1 diguanylate cyclase 1045429 7677858 BMEA_A1098 Brucella melitensis ATCC 23457 diguanylate cyclase YP_002732793.1 1044635 R 546272 CDS YP_002732794.1 225852561 7677859 complement(1045994..1047484) 1 NC_012441.1 succinate CoA transferase 1047484 7677859 BMEA_A1099 Brucella melitensis ATCC 23457 succinate CoA transferase YP_002732794.1 1045994 R 546272 CDS YP_002732795.1 225852562 7677860 complement(1047749..1049290) 1 NC_012441.1 drug resistance transporter, EmrB/QacA subfamily protein 1049290 7677860 BMEA_A1100 Brucella melitensis ATCC 23457 drug resistance transporter, EmrB/QacA subfamily protein YP_002732795.1 1047749 R 546272 CDS YP_002732796.1 225852563 7677861 complement(1049290..1050390) 1 NC_012441.1 secretion protein HlyD family protein 1050390 7677861 BMEA_A1101 Brucella melitensis ATCC 23457 secretion protein HlyD family protein YP_002732796.1 1049290 R 546272 CDS YP_002732797.1 225852564 7677862 1050784..1051767 1 NC_012441.1 zinc-binding alcohol dehydrogenase family protein 1051767 7677862 BMEA_A1102 Brucella melitensis ATCC 23457 zinc-binding alcohol dehydrogenase family protein YP_002732797.1 1050784 D 546272 CDS YP_002732798.1 225852565 7677863 complement(1051811..1052953) 1 NC_012441.1 Xaa-Pro dipeptidase 1052953 7677863 BMEA_A1103 Brucella melitensis ATCC 23457 Xaa-Pro dipeptidase YP_002732798.1 1051811 R 546272 CDS YP_002732799.1 225852566 7677864 complement(1053212..1054042) 1 NC_012441.1 methyltransferase type 12 1054042 7677864 BMEA_A1104 Brucella melitensis ATCC 23457 methyltransferase type 12 YP_002732799.1 1053212 R 546272 CDS YP_002732800.1 225852567 7677865 complement(1054151..1055116) 1 NC_012441.1 bile acid:sodium symporter 1055116 7677865 BMEA_A1105 Brucella melitensis ATCC 23457 bile acid:sodium symporter YP_002732800.1 1054151 R 546272 CDS YP_002732801.1 225852568 7677866 complement(1055245..1056252) 1 NC_012441.1 UDP-glucose 4-epimerase 1056252 galE 7677866 galE Brucella melitensis ATCC 23457 UDP-glucose 4-epimerase YP_002732801.1 1055245 R 546272 CDS YP_002732802.1 225852569 7677867 1056397..1057221 1 NC_012441.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1057221 7677867 BMEA_A1108 Brucella melitensis ATCC 23457 nucleoside triphosphate pyrophosphohydrolase YP_002732802.1 1056397 D 546272 CDS YP_002732803.1 225852570 7677868 complement(1057230..1057841) 1 NC_012441.1 hypothetical protein 1057841 7677868 BMEA_A1109 Brucella melitensis ATCC 23457 hypothetical protein YP_002732803.1 1057230 R 546272 CDS YP_002732804.1 225852571 7677869 complement(1057884..1058468) 1 NC_012441.1 nitroreductase 1058468 7677869 BMEA_A1110 Brucella melitensis ATCC 23457 nitroreductase YP_002732804.1 1057884 R 546272 CDS YP_002732805.1 225852572 7677870 1058688..1059698 1 NC_012441.1 hypothetical protein 1059698 7677870 BMEA_A1111 Brucella melitensis ATCC 23457 hypothetical protein YP_002732805.1 1058688 D 546272 CDS YP_002732806.1 225852573 7677871 complement(1059753..1061729) 1 NC_012441.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1061729 thrS 7677871 thrS Brucella melitensis ATCC 23457 threonyl-tRNA synthetase YP_002732806.1 1059753 R 546272 CDS YP_002732807.1 225852574 7677873 complement(1063283..1063762) 1 NC_012441.1 hypothetical protein 1063762 7677873 BMEA_A1114 Brucella melitensis ATCC 23457 hypothetical protein YP_002732807.1 1063283 R 546272 CDS YP_002732808.1 225852575 7677874 complement(1063656..1064096) 1 NC_012441.1 nitrogen-fixing NifU domain-containing protein 1064096 7677874 BMEA_A1115 Brucella melitensis ATCC 23457 nitrogen-fixing NifU domain-containing protein YP_002732808.1 1063656 R 546272 CDS YP_002732809.1 225852576 7677875 1064360..1065001 1 NC_012441.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1065001 folE 7677875 folE Brucella melitensis ATCC 23457 GTP cyclohydrolase I YP_002732809.1 1064360 D 546272 CDS YP_002732810.1 225852577 7677876 1065024..1065443 1 NC_012441.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1065443 7677876 BMEA_A1117 Brucella melitensis ATCC 23457 phosphoribosyl-AMP cyclohydrolase YP_002732810.1 1065024 D 546272 CDS YP_002732811.1 225852578 7677877 1065660..1066607 1 NC_012441.1 patatin 1066607 7677877 BMEA_A1118 Brucella melitensis ATCC 23457 patatin YP_002732811.1 1065660 D 546272 CDS YP_002732812.1 225852579 7677878 1066694..1066873 1 NC_012441.1 hypothetical protein 1066873 7677878 BMEA_A1119 Brucella melitensis ATCC 23457 hypothetical protein YP_002732812.1 1066694 D 546272 CDS YP_002732813.1 225852580 7677880 1067081..1068388 1 NC_012441.1 site-specific recombinase, phage integrase family protein 1068388 7677880 BMEA_A1121 Brucella melitensis ATCC 23457 site-specific recombinase, phage integrase family protein YP_002732813.1 1067081 D 546272 CDS YP_002732814.1 225852581 7677881 1068463..1068867 1 NC_012441.1 hypothetical protein 1068867 7677881 BMEA_A1122 Brucella melitensis ATCC 23457 hypothetical protein YP_002732814.1 1068463 D 546272 CDS YP_002732815.1 225852582 7677882 complement(1070613..1072010) 1 NC_012441.1 hypothetical protein 1072010 7677882 BMEA_A1123 Brucella melitensis ATCC 23457 hypothetical protein YP_002732815.1 1070613 R 546272 CDS YP_002732816.1 225852583 7676931 complement(1072535..1073164) 1 NC_012441.1 DNA-invertase 1073164 7676931 BMEA_A1124 Brucella melitensis ATCC 23457 DNA-invertase YP_002732816.1 1072535 R 546272 CDS YP_002732817.1 225852584 7676202 complement(1073432..1073581) 1 NC_012441.1 hypothetical protein 1073581 7676202 BMEA_A1125 Brucella melitensis ATCC 23457 hypothetical protein YP_002732817.1 1073432 R 546272 CDS YP_002732818.1 225852585 7676203 complement(1073660..1073995) 1 NC_012441.1 hypothetical protein 1073995 7676203 BMEA_A1126 Brucella melitensis ATCC 23457 hypothetical protein YP_002732818.1 1073660 R 546272 CDS YP_002732819.1 225852586 7676204 complement(1074279..1074854) 1 NC_012441.1 BRO family protein 1074854 7676204 BMEA_A1127 Brucella melitensis ATCC 23457 BRO family protein YP_002732819.1 1074279 R 546272 CDS YP_002732820.1 225852587 7676206 complement(1075381..1076526) 1 NC_012441.1 acyl-CoA transferase/carnitine dehydratase 1076526 7676206 BMEA_A1129 Brucella melitensis ATCC 23457 acyl-CoA transferase/carnitine dehydratase YP_002732820.1 1075381 R 546272 CDS YP_002732821.1 225852588 7676207 complement(1076605..1077789) 1 NC_012441.1 glutaryl-CoA dehydrogenase 1077789 7676207 BMEA_A1130 Brucella melitensis ATCC 23457 glutaryl-CoA dehydrogenase YP_002732821.1 1076605 R 546272 CDS YP_002732822.1 225852589 7676209 complement(1078792..1079775) 1 NC_012441.1 luciferase family protein 1079775 7676209 BMEA_A1132 Brucella melitensis ATCC 23457 luciferase family protein YP_002732822.1 1078792 R 546272 CDS YP_002732823.1 225852590 7676210 complement(1079856..1082945) 1 NC_012441.1 acriflavin resistance protein 1082945 7676210 BMEA_A1133 Brucella melitensis ATCC 23457 acriflavin resistance protein YP_002732823.1 1079856 R 546272 CDS YP_002732824.1 225852591 7676211 complement(1082955..1084136) 1 NC_012441.1 RND family efflux transporter 1084136 7676211 BMEA_A1134 Brucella melitensis ATCC 23457 RND family efflux transporter YP_002732824.1 1082955 R 546272 CDS YP_002732825.1 225852592 7676212 1084244..1084810 1 NC_012441.1 TetR family transcriptional regulator 1084810 7676212 BMEA_A1135 Brucella melitensis ATCC 23457 TetR family transcriptional regulator YP_002732825.1 1084244 D 546272 CDS YP_002732826.1 225852593 7676213 complement(1084847..1085980) 1 NC_012441.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1085980 tgt 7676213 tgt Brucella melitensis ATCC 23457 queuine tRNA-ribosyltransferase YP_002732826.1 1084847 R 546272 CDS YP_002732827.1 225852594 7676214 complement(1085977..1087068) 1 NC_012441.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1087068 7676214 BMEA_A1137 Brucella melitensis ATCC 23457 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002732827.1 1085977 R 546272 CDS YP_002732828.1 225852595 7676215 complement(1087190..1087696) 1 NC_012441.1 cyclophilin type peptidyl-prolyl cis-trans isomerase 1087696 7676215 BMEA_A1138 Brucella melitensis ATCC 23457 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_002732828.1 1087190 R 546272 CDS YP_002732829.1 225852596 7676216 complement(1087759..1088349) 1 NC_012441.1 cyclophilin type peptidyl-prolyl cis-trans isomerase 1088349 7676216 BMEA_A1139 Brucella melitensis ATCC 23457 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_002732829.1 1087759 R 546272 CDS YP_002732830.1 225852597 7676217 complement(1088370..1088864) 1 NC_012441.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1088864 coaD 7676217 coaD Brucella melitensis ATCC 23457 phosphopantetheine adenylyltransferase YP_002732830.1 1088370 R 546272 CDS YP_002732831.1 225852598 7676218 1089059..1089208 1 NC_012441.1 hypothetical protein 1089208 7676218 BMEA_A1142 Brucella melitensis ATCC 23457 hypothetical protein YP_002732831.1 1089059 D 546272 CDS YP_002732832.1 225852599 7676219 complement(1089080..1089319) 1 NC_012441.1 hypothetical protein 1089319 7676219 BMEA_A1143 Brucella melitensis ATCC 23457 hypothetical protein YP_002732832.1 1089080 R 546272 CDS YP_002732833.1 225852600 7676220 complement(1089375..1092143) 1 NC_012441.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1092143 gyrA 7676220 gyrA Brucella melitensis ATCC 23457 DNA gyrase subunit A YP_002732833.1 1089375 R 546272 CDS YP_002732834.1 225852601 7676221 1092431..1093060 1 NC_012441.1 hypothetical protein 1093060 7676221 BMEA_A1145 Brucella melitensis ATCC 23457 hypothetical protein YP_002732834.1 1092431 D 546272 CDS YP_002732835.1 225852602 7676222 complement(1093151..1093729) 1 NC_012441.1 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 1093729 phnN 7676222 phnN Brucella melitensis ATCC 23457 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN YP_002732835.1 1093151 R 546272 CDS YP_002732836.1 225852603 7676223 1093916..1094677 1 NC_012441.1 phosphonates metabolism transcriptional regulator PhnF 1094677 phnF 7676223 phnF Brucella melitensis ATCC 23457 phosphonates metabolism transcriptional regulator PhnF YP_002732836.1 1093916 D 546272 CDS YP_002732837.1 225852604 7676224 complement(1095363..1095869) 1 NC_012441.1 single-strand binding protein 1095869 ssb 7676224 ssb Brucella melitensis ATCC 23457 single-strand binding protein YP_002732837.1 1095363 R 546272 CDS YP_002732838.1 225852605 7676225 1096437..1096637 1 NC_012441.1 hypothetical protein 1096637 7676225 BMEA_A1149 Brucella melitensis ATCC 23457 hypothetical protein YP_002732838.1 1096437 D 546272 CDS YP_002732839.1 225852606 7676226 1096768..1099692 1 NC_012441.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1099692 uvrA 7676226 uvrA Brucella melitensis ATCC 23457 excinuclease ABC subunit A YP_002732839.1 1096768 D 546272 CDS YP_002732840.1 225852607 7676227 complement(1099879..1100154) 1 NC_012441.1 DNA-binding protein HRL18 1100154 7676227 BMEA_A1151 Brucella melitensis ATCC 23457 DNA-binding protein HRL18 YP_002732840.1 1099879 R 546272 CDS YP_002732841.1 225852608 7676228 complement(1100335..1102773) 1 NC_012441.1 ATP-dependent protease La 1102773 lon 7676228 lon Brucella melitensis ATCC 23457 ATP-dependent protease La YP_002732841.1 1100335 R 546272 CDS YP_002732842.1 225852609 7676229 complement(1103205..1104479) 1 NC_012441.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1104479 clpX 7676229 clpX Brucella melitensis ATCC 23457 ATP-dependent protease ATP-binding subunit ClpX YP_002732842.1 1103205 R 546272 CDS YP_002732843.1 225852610 7676230 complement(1104861..1105490) 1 NC_012441.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1105490 7676230 BMEA_A1154 Brucella melitensis ATCC 23457 ATP-dependent Clp protease proteolytic subunit YP_002732843.1 1104861 R 546272 CDS YP_002732844.1 225852611 7676231 complement(1105595..1107013) 1 NC_012441.1 GTP-binding proten HflX 1107013 hflX 7676231 hflX Brucella melitensis ATCC 23457 GTP-binding proten HflX YP_002732844.1 1105595 R 546272 CDS YP_002732845.1 225852612 7676232 complement(1107204..1107440) 1 NC_012441.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1107440 hfq 7676232 hfq Brucella melitensis ATCC 23457 RNA-binding protein Hfq YP_002732845.1 1107204 R 546272 CDS YP_002732846.1 225852613 7676233 complement(1107446..1107685) 1 NC_012441.1 hypothetical protein 1107685 7676233 BMEA_A1157 Brucella melitensis ATCC 23457 hypothetical protein YP_002732846.1 1107446 R 546272 CDS YP_002732847.1 225852614 7676234 complement(1107669..1108499) 1 NC_012441.1 hypothetical protein 1108499 7676234 BMEA_A1158 Brucella melitensis ATCC 23457 hypothetical protein YP_002732847.1 1107669 R 546272 CDS YP_002732848.1 225852615 7676235 complement(1108548..1109924) 1 NC_012441.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1109924 7676235 BMEA_A1159 Brucella melitensis ATCC 23457 potassium transporter peripheral membrane protein YP_002732848.1 1108548 R 546272 CDS YP_002732849.1 225852616 7676236 complement(1109949..1111310) 1 NC_012441.1 nitrogen assimilation regulatory protein 1111310 7676236 BMEA_A1160 Brucella melitensis ATCC 23457 nitrogen assimilation regulatory protein YP_002732849.1 1109949 R 546272 CDS YP_002732850.1 225852617 7676237 complement(1111312..1113636) 1 NC_012441.1 PAS domain S-box-containing protein 1113636 7676237 BMEA_A1161 Brucella melitensis ATCC 23457 PAS domain S-box-containing protein YP_002732850.1 1111312 R 546272 CDS YP_002732851.1 225852618 7676238 complement(1113727..1115202) 1 NC_012441.1 nitrogen regulation protein NR(I) 1115202 ntrC 7676238 ntrC Brucella melitensis ATCC 23457 nitrogen regulation protein NR(I) YP_002732851.1 1113727 R 546272 CDS YP_002732852.1 225852619 7676239 complement(1115199..1116341) 1 NC_012441.1 nitrogen regulation protein ntrB 1116341 7676239 BMEA_A1163 Brucella melitensis ATCC 23457 nitrogen regulation protein ntrB YP_002732852.1 1115199 R 546272 CDS YP_002732853.1 225852620 7676240 complement(1116341..1117342) 1 NC_012441.1 TIM-barrel protein nifR3 family protein 1117342 7676240 BMEA_A1164 Brucella melitensis ATCC 23457 TIM-barrel protein nifR3 family protein YP_002732853.1 1116341 R 546272 CDS YP_002732854.1 225852621 7676241 1117354..1118709 1 NC_012441.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 1118709 ispF 7676241 ispF Brucella melitensis ATCC 23457 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein YP_002732854.1 1117354 D 546272 CDS YP_002732855.1 225852622 7676242 1118706..1119203 1 NC_012441.1 CinA domain-containing protein 1119203 7676242 BMEA_A1166 Brucella melitensis ATCC 23457 CinA domain-containing protein YP_002732855.1 1118706 D 546272 CDS YP_002732856.1 225852623 7676244 complement(1120080..1120538) 1 NC_012441.1 cyclase/dehydrase 1120538 7676244 BMEA_A1168 Brucella melitensis ATCC 23457 cyclase/dehydrase YP_002732856.1 1120080 R 546272 CDS YP_002732857.1 225852624 7676245 complement(1120544..1121512) 1 NC_012441.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1121512 lipA 7676245 lipA Brucella melitensis ATCC 23457 lipoyl synthase YP_002732857.1 1120544 R 546272 CDS YP_002732858.1 225852625 7676246 complement(1121622..1121783) 1 NC_012441.1 hypothetical protein 1121783 7676246 BMEA_A1170 Brucella melitensis ATCC 23457 hypothetical protein YP_002732858.1 1121622 R 546272 CDS YP_002732859.1 225852626 7676247 complement(1121902..1123365) 1 NC_012441.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1123365 lpdA 7676247 lpdA Brucella melitensis ATCC 23457 dihydrolipoamide dehydrogenase YP_002732859.1 1121902 R 546272 CDS YP_002732860.1 225852627 7676248 complement(1123448..1124791) 1 NC_012441.1 branched-chain alpha-keto acid dehydrogenase subunit E2 1124791 7676248 BMEA_A1172 Brucella melitensis ATCC 23457 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002732860.1 1123448 R 546272 CDS YP_002732861.1 225852628 7676249 complement(1124809..1126194) 1 NC_012441.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 1126194 7676249 BMEA_A1173 Brucella melitensis ATCC 23457 pyruvate dehydrogenase subunit beta YP_002732861.1 1124809 R 546272 CDS YP_002732862.1 225852629 7676250 complement(1126213..1127253) 1 NC_012441.1 dehydrogenase E1 component 1127253 pdhA 7676250 pdhA Brucella melitensis ATCC 23457 dehydrogenase E1 component YP_002732862.1 1126213 R 546272 CDS YP_002732863.1 225852630 7676251 complement(1127392..1127721) 1 NC_012441.1 septum formation initiator 1127721 7676251 BMEA_A1175 Brucella melitensis ATCC 23457 septum formation initiator YP_002732863.1 1127392 R 546272 CDS YP_002732864.1 225852631 7676252 complement(1127993..1128574) 1 NC_012441.1 hypothetical protein 1128574 7676252 BMEA_A1176 Brucella melitensis ATCC 23457 hypothetical protein YP_002732864.1 1127993 R 546272 CDS YP_002732865.1 225852632 7676253 complement(1128911..1130188) 1 NC_012441.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1130188 eno 7676253 eno Brucella melitensis ATCC 23457 phosphopyruvate hydratase YP_002732865.1 1128911 R 546272 CDS YP_002732866.1 225852633 7676254 complement(1130375..1131208) 1 NC_012441.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1131208 kdsA 7676254 kdsA Brucella melitensis ATCC 23457 2-dehydro-3-deoxyphosphooctonate aldolase YP_002732866.1 1130375 R 546272 CDS YP_002732867.1 225852634 7676255 complement(1131314..1132942) 1 NC_012441.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1132942 pyrG 7676255 pyrG Brucella melitensis ATCC 23457 CTP synthetase YP_002732867.1 1131314 R 546272 CDS YP_002732868.1 225852635 7676256 complement(1133212..1133904) 1 NC_012441.1 ErfK/YbiS/YcfS/YnhG family protein 1133904 7676256 BMEA_A1180 Brucella melitensis ATCC 23457 ErfK/YbiS/YcfS/YnhG family protein YP_002732868.1 1133212 R 546272 CDS YP_002732869.1 225852636 7676257 complement(1134158..1134604) 1 NC_012441.1 preprotein translocase subunit SecG 1134604 secG 7676257 secG Brucella melitensis ATCC 23457 preprotein translocase subunit SecG YP_002732869.1 1134158 R 546272 CDS YP_002732870.1 225852637 7676258 complement(1134704..1135468) 1 NC_012441.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1135468 tpiA 7676258 tpiA Brucella melitensis ATCC 23457 triosephosphate isomerase YP_002732870.1 1134704 R 546272 CDS YP_002732871.1 225852638 7676259 1135687..1137573 1 NC_012441.1 rotamase family protein 1137573 7676259 BMEA_A1183 Brucella melitensis ATCC 23457 rotamase family protein YP_002732871.1 1135687 D 546272 CDS YP_002732872.1 225852639 7676260 1137588..1138607 1 NC_012441.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1138607 trpD 7676260 trpD Brucella melitensis ATCC 23457 anthranilate phosphoribosyltransferase YP_002732872.1 1137588 D 546272 CDS YP_002732873.1 225852640 7676261 1138624..1139430 1 NC_012441.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1139430 7676261 BMEA_A1185 Brucella melitensis ATCC 23457 indole-3-glycerol-phosphate synthase YP_002732873.1 1138624 D 546272 CDS YP_002732874.1 225852641 7676262 1139427..1139924 1 NC_012441.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1139924 moaC 7676262 moaC Brucella melitensis ATCC 23457 molybdenum cofactor biosynthesis protein MoaC YP_002732874.1 1139427 D 546272 CDS YP_002732875.1 225852642 7676263 1140020..1141234 1 NC_012441.1 molybdenum cofactor synthesis domain-containing protein 1141234 7676263 BMEA_A1187 Brucella melitensis ATCC 23457 molybdenum cofactor synthesis domain-containing protein YP_002732875.1 1140020 D 546272 CDS YP_002732876.1 225852643 7676264 1141482..1142204 1 NC_012441.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 1142204 lexA 7676264 lexA Brucella melitensis ATCC 23457 LexA repressor YP_002732876.1 1141482 D 546272 CDS YP_002732877.1 225852644 7676266 complement(1144760..1144936) 1 NC_012441.1 hypothetical protein 1144936 7676266 BMEA_A1190 Brucella melitensis ATCC 23457 hypothetical protein YP_002732877.1 1144760 R 546272 CDS YP_002732878.1 225852645 7676267 1144949..1146370 1 NC_012441.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1146370 gltX 7676267 gltX Brucella melitensis ATCC 23457 glutamyl-tRNA synthetase YP_002732878.1 1144949 D 546272 CDS YP_002732879.1 225852646 7676268 1146599..1147891 1 NC_012441.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1147891 gltA 7676268 gltA Brucella melitensis ATCC 23457 type II citrate synthase YP_002732879.1 1146599 D 546272 CDS YP_002732880.1 225852647 7676269 complement(1148064..1149251) 1 NC_012441.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1149251 lpxB 7676269 lpxB Brucella melitensis ATCC 23457 lipid-A-disaccharide synthase YP_002732880.1 1148064 R 546272 CDS YP_002732881.1 225852648 7676270 complement(1149248..1150150) 1 NC_012441.1 hypothetical protein 1150150 7676270 BMEA_A1194 Brucella melitensis ATCC 23457 hypothetical protein YP_002732881.1 1149248 R 546272 CDS YP_002732882.1 225852649 7676271 complement(1150131..1150967) 1 NC_012441.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1150967 lpxA 7676271 lpxA Brucella melitensis ATCC 23457 UDP-N-acetylglucosamine acyltransferase YP_002732882.1 1150131 R 546272 CDS YP_002732883.1 225852650 7676272 complement(1150976..1151449) 1 NC_012441.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1151449 fabZ 7676272 fabZ Brucella melitensis ATCC 23457 (3R)-hydroxymyristoyl-ACP dehydratase YP_002732883.1 1150976 R 546272 CDS YP_002732884.1 225852651 7676273 complement(1151442..1152497) 1 NC_012441.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1152497 lpxD 7676273 lpxD Brucella melitensis ATCC 23457 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002732884.1 1151442 R 546272 CDS YP_002732885.1 225852652 7676274 complement(1152551..1154896) 1 NC_012441.1 outer membrane protein assembly complex protein YaeT 1154896 yaeT 7676274 yaeT Brucella melitensis ATCC 23457 outer membrane protein assembly complex protein YaeT YP_002732885.1 1152551 R 546272 CDS YP_002732886.1 225852653 7676275 complement(1155232..1156371) 1 NC_012441.1 membrane-associated zinc metalloprotease 1156371 7676275 BMEA_A1199 Brucella melitensis ATCC 23457 membrane-associated zinc metalloprotease YP_002732886.1 1155232 R 546272 CDS YP_002732887.1 225852654 7676276 complement(1156438..1157250) 1 NC_012441.1 phosphatidate cytidylyltransferase 1157250 7676276 BMEA_A1200 Brucella melitensis ATCC 23457 phosphatidate cytidylyltransferase YP_002732887.1 1156438 R 546272 CDS YP_002732888.1 225852655 7676277 complement(1157355..1158119) 1 NC_012441.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1158119 uppS 7676277 uppS Brucella melitensis ATCC 23457 UDP pyrophosphate synthase YP_002732888.1 1157355 R 546272 CDS YP_002732889.1 225852656 7676278 complement(1158164..1158724) 1 NC_012441.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1158724 frr 7676278 frr Brucella melitensis ATCC 23457 ribosome recycling factor YP_002732889.1 1158164 R 546272 CDS YP_002732890.1 225852657 7676279 complement(1158760..1159731) 1 NC_012441.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1159731 pyrH 7676279 pyrH Brucella melitensis ATCC 23457 uridylate kinase YP_002732890.1 1158760 R 546272 CDS YP_002732891.1 225852658 7676280 complement(1159649..1160566) 1 NC_012441.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1160566 tsf 7676280 tsf Brucella melitensis ATCC 23457 elongation factor Ts YP_002732891.1 1159649 R 546272 CDS YP_002732892.1 225852659 7676932 complement(1160756..1161526) 1 NC_012441.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1161526 rpsB 7676932 rpsB Brucella melitensis ATCC 23457 30S ribosomal protein S2 YP_002732892.1 1160756 R 546272 CDS YP_002732893.1 225852660 7676933 complement(1161749..1162243) 1 NC_012441.1 hypothetical protein 1162243 7676933 BMEA_A1206 Brucella melitensis ATCC 23457 hypothetical protein YP_002732893.1 1161749 R 546272 CDS YP_002732894.1 225852661 7676934 complement(1162355..1163197) 1 NC_012441.1 hypothetical protein 1163197 7676934 BMEA_A1207 Brucella melitensis ATCC 23457 hypothetical protein YP_002732894.1 1162355 R 546272 CDS YP_002732895.1 225852662 7677091 1163342..1163806 1 NC_012441.1 endoribonuclease L-PSP 1163806 7677091 BMEA_A1208 Brucella melitensis ATCC 23457 endoribonuclease L-PSP YP_002732895.1 1163342 D 546272 CDS YP_002732896.1 225852663 7677092 1163808..1164548 1 NC_012441.1 glycerophosphoryl diester phosphodiesterase 1164548 7677092 BMEA_A1209 Brucella melitensis ATCC 23457 glycerophosphoryl diester phosphodiesterase YP_002732896.1 1163808 D 546272 CDS YP_002732897.1 225852664 7677093 1164603..1165790 1 NC_012441.1 hypothetical protein 1165790 7677093 BMEA_A1210 Brucella melitensis ATCC 23457 hypothetical protein YP_002732897.1 1164603 D 546272 CDS YP_002732898.1 225852665 7677094 1165862..1166284 1 NC_012441.1 histidine triad protein 1166284 7677094 BMEA_A1211 Brucella melitensis ATCC 23457 histidine triad protein YP_002732898.1 1165862 D 546272 CDS YP_002732899.1 225852666 7677095 complement(1166391..1168865) 1 NC_012441.1 ATP-dependent Clp protease ATP-binding subunit ClpA 1168865 clpA 7677095 clpA Brucella melitensis ATCC 23457 ATP-dependent Clp protease ATP-binding subunit ClpA YP_002732899.1 1166391 R 546272 CDS YP_002732900.1 225852667 7677096 complement(1168872..1169222) 1 NC_012441.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1169222 7677096 BMEA_A1213 Brucella melitensis ATCC 23457 ATP-dependent Clp protease adaptor protein ClpS YP_002732900.1 1168872 R 546272 CDS YP_002732901.1 225852668 7677097 1169283..1169474 1 NC_012441.1 hypothetical protein 1169474 7677097 BMEA_A1214 Brucella melitensis ATCC 23457 hypothetical protein YP_002732901.1 1169283 D 546272 CDS YP_002732902.1 225852669 7677098 1169708..1171126 1 NC_012441.1 serine-type D-Ala-D-Ala carboxypeptidase 1171126 7677098 BMEA_A1215 Brucella melitensis ATCC 23457 serine-type D-Ala-D-Ala carboxypeptidase YP_002732902.1 1169708 D 546272 CDS YP_002732903.1 225852670 7677099 1171158..1171499 1 NC_012441.1 hypothetical protein 1171499 7677099 BMEA_A1216 Brucella melitensis ATCC 23457 hypothetical protein YP_002732903.1 1171158 D 546272 CDS YP_002732904.1 225852671 7677100 complement(1171613..1172050) 1 NC_012441.1 hypothetical protein 1172050 7677100 BMEA_A1218 Brucella melitensis ATCC 23457 hypothetical protein YP_002732904.1 1171613 R 546272 CDS YP_002732905.1 225852672 7677101 complement(1172139..1173542) 1 NC_012441.1 L-serine ammonia-lyase 1173542 sdaA 7677101 sdaA Brucella melitensis ATCC 23457 L-serine ammonia-lyase YP_002732905.1 1172139 R 546272 CDS YP_002732906.1 225852673 7677102 complement(1173740..1173865) 1 NC_012441.1 hypothetical protein 1173865 7677102 BMEA_A1221 Brucella melitensis ATCC 23457 hypothetical protein YP_002732906.1 1173740 R 546272 CDS YP_002732907.1 225852674 7677103 complement(1174064..1174858) 1 NC_012441.1 hypothetical protein 1174858 7677103 BMEA_A1222 Brucella melitensis ATCC 23457 hypothetical protein YP_002732907.1 1174064 R 546272 CDS YP_002732908.1 225852675 7677104 complement(1176029..1176415) 1 NC_012441.1 MerR family transcriptional regulator 1176415 7677104 BMEA_A1223 Brucella melitensis ATCC 23457 MerR family transcriptional regulator YP_002732908.1 1176029 R 546272 CDS YP_002732909.1 225852676 7677105 1176653..1177018 1 NC_012441.1 hypothetical protein 1177018 7677105 BMEA_A1224 Brucella melitensis ATCC 23457 hypothetical protein YP_002732909.1 1176653 D 546272 CDS YP_002732910.1 225852677 7677106 1177033..1177380 1 NC_012441.1 hypothetical protein 1177380 7677106 BMEA_A1225 Brucella melitensis ATCC 23457 hypothetical protein YP_002732910.1 1177033 D 546272 CDS YP_002732911.1 225852678 7677107 1177451..1177765 1 NC_012441.1 hypothetical protein 1177765 7677107 BMEA_A1226 Brucella melitensis ATCC 23457 hypothetical protein YP_002732911.1 1177451 D 546272 CDS YP_002732912.1 225852679 7677108 1178061..1178528 1 NC_012441.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1178528 queF 7677108 queF Brucella melitensis ATCC 23457 7-cyano-7-deazaguanine reductase YP_002732912.1 1178061 D 546272 CDS YP_002732913.1 225852680 7677109 complement(1178532..1178681) 1 NC_012441.1 hypothetical protein 1178681 7677109 BMEA_A1228 Brucella melitensis ATCC 23457 hypothetical protein YP_002732913.1 1178532 R 546272 CDS YP_002732914.1 225852681 7677110 1178659..1178835 1 NC_012441.1 hypothetical protein 1178835 7677110 BMEA_A1229 Brucella melitensis ATCC 23457 hypothetical protein YP_002732914.1 1178659 D 546272 CDS YP_002732915.1 225852682 7677111 1178867..1179409 1 NC_012441.1 hypothetical protein 1179409 7677111 BMEA_A1230 Brucella melitensis ATCC 23457 hypothetical protein YP_002732915.1 1178867 D 546272 CDS YP_002732916.1 225852683 7677112 complement(1179412..1180824) 1 NC_012441.1 hypothetical protein 1180824 7677112 BMEA_A1231 Brucella melitensis ATCC 23457 hypothetical protein YP_002732916.1 1179412 R 546272 CDS YP_002732917.1 225852684 7677113 1181773..1182507 1 NC_012441.1 propionyl-CoA carboxylase subunit beta 1182507 7677113 BMEA_A1232 Brucella melitensis ATCC 23457 propionyl-CoA carboxylase subunit beta YP_002732917.1 1181773 D 546272 CDS YP_002732918.1 225852685 7677114 1182592..1184595 1 NC_012441.1 propionyl-coenzyme A carboxylase subunit alpha 1184595 7677114 BMEA_A1233 Brucella melitensis ATCC 23457 propionyl-coenzyme A carboxylase subunit alpha YP_002732918.1 1182592 D 546272 CDS YP_002732919.1 225852686 7677115 1184656..1186794 1 NC_012441.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1186794 7677115 BMEA_A1234 Brucella melitensis ATCC 23457 methylmalonyl-CoA mutase YP_002732919.1 1184656 D 546272 CDS YP_002732920.1 225852687 7677116 complement(1186901..1187263) 1 NC_012441.1 hypothetical protein 1187263 7677116 BMEA_A1235 Brucella melitensis ATCC 23457 hypothetical protein YP_002732920.1 1186901 R 546272 CDS YP_002732921.1 225852688 7677117 complement(1187450..1189498) 1 NC_012441.1 TRAP transporter transmembrane protein 1189498 7677117 BMEA_A1236 Brucella melitensis ATCC 23457 TRAP transporter transmembrane protein YP_002732921.1 1187450 R 546272 CDS YP_002732922.1 225852689 7677118 complement(1189539..1189685) 1 NC_012441.1 hypothetical protein 1189685 7677118 BMEA_A1237 Brucella melitensis ATCC 23457 hypothetical protein YP_002732922.1 1189539 R 546272 CDS YP_002732923.1 225852690 7677119 complement(1189735..1190724) 1 NC_012441.1 TRAP transporter solute receptor 1190724 7677119 BMEA_A1238 Brucella melitensis ATCC 23457 TRAP transporter solute receptor YP_002732923.1 1189735 R 546272 CDS YP_002732924.1 225852691 7677120 complement(1190870..1191703) 1 NC_012441.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1191703 murI 7677120 murI Brucella melitensis ATCC 23457 glutamate racemase YP_002732924.1 1190870 R 546272 CDS YP_002732925.1 225852692 7677121 complement(1191700..1192530) 1 NC_012441.1 TrmH family RNA methyltransferase 1192530 7677121 BMEA_A1240 Brucella melitensis ATCC 23457 TrmH family RNA methyltransferase YP_002732925.1 1191700 R 546272 CDS YP_002732926.1 225852693 7677122 1192710..1193294 1 NC_012441.1 Pfpi family intracellular protease 1193294 7677122 BMEA_A1241 Brucella melitensis ATCC 23457 Pfpi family intracellular protease YP_002732926.1 1192710 D 546272 CDS YP_002732927.1 225852694 7677123 1193383..1193793 1 NC_012441.1 hypothetical protein 1193793 7677123 BMEA_A1242 Brucella melitensis ATCC 23457 hypothetical protein YP_002732927.1 1193383 D 546272 CDS YP_002732928.1 225852695 7677124 1193921..1195135 1 NC_012441.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1195135 7677124 BMEA_A1243 Brucella melitensis ATCC 23457 isocitrate dehydrogenase YP_002732928.1 1193921 D 546272 CDS YP_002732929.1 225852696 7677125 1195357..1196802 1 NC_012441.1 alkaline phosphatase 1196802 7677125 BMEA_A1244 Brucella melitensis ATCC 23457 alkaline phosphatase YP_002732929.1 1195357 D 546272 CDS YP_002732930.1 225852697 7677126 complement(1196954..1199611) 1 NC_012441.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1199611 alaS 7677126 alaS Brucella melitensis ATCC 23457 alanyl-tRNA synthetase YP_002732930.1 1196954 R 546272 CDS YP_002732931.1 225852698 7677127 complement(1200004..1201089) 1 NC_012441.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1201089 recA 7677127 recA Brucella melitensis ATCC 23457 recombinase A YP_002732931.1 1200004 R 546272 CDS YP_002732932.1 225852699 7677128 complement(1201259..1201384) 1 NC_012441.1 hypothetical protein 1201384 7677128 BMEA_A1247 Brucella melitensis ATCC 23457 hypothetical protein YP_002732932.1 1201259 R 546272 CDS YP_002732933.1 225852700 7677129 complement(1201420..1202082) 1 NC_012441.1 OmpA/MotB domain-containing protein 1202082 7677129 BMEA_A1248 Brucella melitensis ATCC 23457 OmpA/MotB domain-containing protein YP_002732933.1 1201420 R 546272 CDS YP_002732934.1 225852701 7677130 complement(1202169..1202753) 1 NC_012441.1 lytic transglycosylase 1202753 7677130 BMEA_A1249 Brucella melitensis ATCC 23457 lytic transglycosylase YP_002732934.1 1202169 R 546272 CDS YP_002732935.1 225852702 7677131 complement(1202877..1204190) 1 NC_012441.1 recombination factor protein RarA 1204190 7677131 BMEA_A1250 Brucella melitensis ATCC 23457 recombination factor protein RarA YP_002732935.1 1202877 R 546272 CDS YP_002732936.1 225852703 7677132 complement(1204337..1205761) 1 NC_012441.1 protease Do 1205761 degP 7677132 degP Brucella melitensis ATCC 23457 protease Do YP_002732936.1 1204337 R 546272 CDS YP_002732937.1 225852704 7677133 complement(1206041..1206469) 1 NC_012441.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1206469 rplQ 7677133 rplQ Brucella melitensis ATCC 23457 50S ribosomal protein L17 YP_002732937.1 1206041 R 546272 CDS YP_002732938.1 225852705 7677134 complement(1206631..1207644) 1 NC_012441.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1207644 rpoA 7677134 rpoA Brucella melitensis ATCC 23457 DNA-directed RNA polymerase subunit alpha YP_002732938.1 1206631 R 546272 CDS YP_002732939.1 225852706 7677135 complement(1207760..1208149) 1 NC_012441.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1208149 7677135 BMEA_A1254 Brucella melitensis ATCC 23457 30S ribosomal protein S11 YP_002732939.1 1207760 R 546272 CDS YP_002732940.1 225852707 7677136 complement(1208277..1208645) 1 NC_012441.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1208645 7677136 BMEA_A1255 Brucella melitensis ATCC 23457 30S ribosomal protein S13 YP_002732940.1 1208277 R 546272 CDS YP_002732941.1 225852708 7677137 1208639..1208812 1 NC_012441.1 hypothetical protein 1208812 7677137 BMEA_A1256 Brucella melitensis ATCC 23457 hypothetical protein YP_002732941.1 1208639 D 546272 CDS YP_002732942.1 225852709 7677138 complement(1208955..1209539) 1 NC_012441.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1209539 7677138 BMEA_A1257 Brucella melitensis ATCC 23457 adenylate kinase YP_002732942.1 1208955 R 546272 CDS YP_002732943.1 225852710 7677139 complement(1209536..1210876) 1 NC_012441.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1210876 secY 7677139 secY Brucella melitensis ATCC 23457 preprotein translocase subunit SecY YP_002732943.1 1209536 R 546272 CDS YP_002732944.1 225852711 7677140 complement(1211037..1211507) 1 NC_012441.1 late assembly protein; 50S ribosomal protein L15 1211507 rplO 7677140 rplO Brucella melitensis ATCC 23457 50S ribosomal protein L15 YP_002732944.1 1211037 R 546272 CDS YP_002732945.1 225852712 7677141 complement(1211528..1211725) 1 NC_012441.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1211725 rpmD 7677141 rpmD Brucella melitensis ATCC 23457 50S ribosomal protein L30 YP_002732945.1 1211528 R 546272 CDS YP_002732946.1 225852713 7677142 complement(1211843..1212403) 1 NC_012441.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1212403 rpsE 7677142 rpsE Brucella melitensis ATCC 23457 30S ribosomal protein S5 YP_002732946.1 1211843 R 546272 CDS YP_002732947.1 225852714 7677143 complement(1212445..1212807) 1 NC_012441.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1212807 rplR 7677143 rplR Brucella melitensis ATCC 23457 50S ribosomal protein L18 YP_002732947.1 1212445 R 546272 CDS YP_002732948.1 225852715 7677144 complement(1212820..1213353) 1 NC_012441.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1213353 7677144 BMEA_A1263 Brucella melitensis ATCC 23457 50S ribosomal protein L6 YP_002732948.1 1212820 R 546272 CDS YP_002732949.1 225852716 7677145 complement(1213392..1213790) 1 NC_012441.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1213790 7677145 BMEA_A1264 Brucella melitensis ATCC 23457 30S ribosomal protein S8 YP_002732949.1 1213392 R 546272 CDS YP_002732950.1 225852717 7677146 complement(1213801..1214106) 1 NC_012441.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1214106 7677146 BMEA_A1265 Brucella melitensis ATCC 23457 30S ribosomal protein S14 YP_002732950.1 1213801 R 546272 CDS YP_002732951.1 225852718 7677147 complement(1214134..1214691) 1 NC_012441.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1214691 7677147 BMEA_A1266 Brucella melitensis ATCC 23457 50S ribosomal protein L5 YP_002732951.1 1214134 R 546272 CDS YP_002732952.1 225852719 7677148 complement(1214684..1214995) 1 NC_012441.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1214995 rplX 7677148 rplX Brucella melitensis ATCC 23457 50S ribosomal protein L24 YP_002732952.1 1214684 R 546272 CDS YP_002732953.1 225852720 7677149 complement(1215008..1215376) 1 NC_012441.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1215376 rplN 7677149 rplN Brucella melitensis ATCC 23457 50S ribosomal protein L14 YP_002732953.1 1215008 R 546272 CDS YP_002732954.1 225852721 7677150 complement(1215445..1215687) 1 NC_012441.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1215687 7677150 BMEA_A1269 Brucella melitensis ATCC 23457 30S ribosomal protein S17 YP_002732954.1 1215445 R 546272 CDS YP_002732955.1 225852722 7677151 complement(1215700..1215900) 1 NC_012441.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1215900 rpmC 7677151 rpmC Brucella melitensis ATCC 23457 50S ribosomal protein L29 YP_002732955.1 1215700 R 546272 CDS YP_002732956.1 225852723 7677152 complement(1215913..1216326) 1 NC_012441.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1216326 rplP 7677152 rplP Brucella melitensis ATCC 23457 50S ribosomal protein L16 YP_002732956.1 1215913 R 546272 CDS YP_002732957.1 225852724 7677153 complement(1216365..1217075) 1 NC_012441.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1217075 rpsC 7677153 rpsC Brucella melitensis ATCC 23457 30S ribosomal protein S3 YP_002732957.1 1216365 R 546272 CDS YP_002732958.1 225852725 7677154 complement(1217075..1217464) 1 NC_012441.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1217464 rplV 7677154 rplV Brucella melitensis ATCC 23457 50S ribosomal protein L22 YP_002732958.1 1217075 R 546272 CDS YP_002732959.1 225852726 7677155 complement(1217467..1217745) 1 NC_012441.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1217745 rpsS 7677155 rpsS Brucella melitensis ATCC 23457 30S ribosomal protein S19 YP_002732959.1 1217467 R 546272 CDS YP_002732960.1 225852727 7677156 complement(1217761..1218594) 1 NC_012441.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1218594 rplB 7677156 rplB Brucella melitensis ATCC 23457 50S ribosomal protein L2 YP_002732960.1 1217761 R 546272 CDS YP_002732961.1 225852728 7677157 complement(1218616..1218909) 1 NC_012441.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1218909 7677157 BMEA_A1276 Brucella melitensis ATCC 23457 50S ribosomal protein L23 YP_002732961.1 1218616 R 546272 CDS YP_002732962.1 225852729 7677158 complement(1218906..1219526) 1 NC_012441.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1219526 7677158 BMEA_A1277 Brucella melitensis ATCC 23457 50S ribosomal protein L4 YP_002732962.1 1218906 R 546272 CDS YP_002732963.1 225852730 7677159 complement(1219526..1220239) 1 NC_012441.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1220239 7677159 BMEA_A1278 Brucella melitensis ATCC 23457 50S ribosomal protein L3 YP_002732963.1 1219526 R 546272 CDS YP_002732964.1 225852731 7677160 complement(1220269..1220577) 1 NC_012441.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1220577 rpsJ 7677160 rpsJ Brucella melitensis ATCC 23457 30S ribosomal protein S10 YP_002732964.1 1220269 R 546272 CDS YP_002732965.1 225852732 7677161 complement(1220638..1221813) 1 NC_012441.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1221813 tuf 7677161 tuf Brucella melitensis ATCC 23457 elongation factor Tu YP_002732965.1 1220638 R 546272 CDS YP_002732966.1 225852733 7677162 complement(1221877..1223961) 1 NC_012441.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1223961 fusA 7677162 fusA Brucella melitensis ATCC 23457 elongation factor G YP_002732966.1 1221877 R 546272 CDS YP_002732967.1 225852734 7677163 complement(1223992..1224462) 1 NC_012441.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1224462 rpsG 7677163 rpsG Brucella melitensis ATCC 23457 30S ribosomal protein S7 YP_002732967.1 1223992 R 546272 CDS YP_002732968.1 225852735 7677164 complement(1224529..1224900) 1 NC_012441.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1224900 rpsL 7677164 rpsL Brucella melitensis ATCC 23457 30S ribosomal protein S12 YP_002732968.1 1224529 R 546272 CDS YP_002732969.1 225852736 7677165 complement(1224990..1225124) 1 NC_012441.1 hypothetical protein 1225124 7677165 BMEA_A1284 Brucella melitensis ATCC 23457 hypothetical protein YP_002732969.1 1224990 R 546272 CDS YP_002732970.1 225852737 7677166 1225332..1225691 1 NC_012441.1 hypothetical protein 1225691 7677166 BMEA_A1285 Brucella melitensis ATCC 23457 hypothetical protein YP_002732970.1 1225332 D 546272 CDS YP_002732971.1 225852738 7677167 complement(1225798..1230000) 1 NC_012441.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1230000 rpoC 7677167 rpoC Brucella melitensis ATCC 23457 DNA-directed RNA polymerase subunit beta' YP_002732971.1 1225798 R 546272 CDS YP_002732972.1 225852739 7677168 complement(1229997..1230122) 1 NC_012441.1 hypothetical protein 1230122 7677168 BMEA_A1287 Brucella melitensis ATCC 23457 hypothetical protein YP_002732972.1 1229997 R 546272 CDS YP_002732973.1 225852740 7677169 complement(1230149..1234282) 1 NC_012441.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1234282 rpoB 7677169 rpoB Brucella melitensis ATCC 23457 DNA-directed RNA polymerase subunit beta YP_002732973.1 1230149 R 546272 CDS YP_002732974.1 225852741 7677639 complement(1234490..1234864) 1 NC_012441.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1234864 rplL 7677639 rplL Brucella melitensis ATCC 23457 50S ribosomal protein L7/L12 YP_002732974.1 1234490 R 546272 CDS YP_002732975.1 225852742 7677018 complement(1234916..1235434) 1 NC_012441.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1235434 7677018 BMEA_A1290 Brucella melitensis ATCC 23457 50S ribosomal protein L10 YP_002732975.1 1234916 R 546272 CDS YP_002732976.1 225852743 7677019 complement(1235825..1236526) 1 NC_012441.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1236526 rplA 7677019 rplA Brucella melitensis ATCC 23457 50S ribosomal protein L1 YP_002732976.1 1235825 R 546272 CDS YP_002732977.1 225852744 7677020 complement(1236531..1236959) 1 NC_012441.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1236959 rplK 7677020 rplK Brucella melitensis ATCC 23457 50S ribosomal protein L11 YP_002732977.1 1236531 R 546272 CDS YP_002732978.1 225852745 7677021 complement(1237162..1237689) 1 NC_012441.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1237689 nusG 7677021 nusG Brucella melitensis ATCC 23457 transcription antitermination protein NusG YP_002732978.1 1237162 R 546272 CDS YP_002732979.1 225852746 7677022 complement(1237713..1237913) 1 NC_012441.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1237913 secE 7677022 secE Brucella melitensis ATCC 23457 preprotein translocase subunit SecE YP_002732979.1 1237713 R 546272 CDS YP_002732980.1 225852747 7677024 complement(1238587..1239762) 1 NC_012441.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1239762 tuf 7677024 tuf Brucella melitensis ATCC 23457 elongation factor Tu YP_002732980.1 1238587 R 546272 CDS YP_002732981.1 225852748 7677025 1239713..1239913 1 NC_012441.1 hypothetical protein 1239913 7677025 BMEA_A1297 Brucella melitensis ATCC 23457 hypothetical protein YP_002732981.1 1239713 D 546272 CDS YP_002732982.1 225852749 7677028 1240393..1241253 1 NC_012441.1 TrmH family RNA methyltransferase 1241253 7677028 BMEA_A1300 Brucella melitensis ATCC 23457 TrmH family RNA methyltransferase YP_002732982.1 1240393 D 546272 CDS YP_002732983.1 225852750 7677029 complement(1241314..1241787) 1 NC_012441.1 hypothetical protein 1241787 7677029 BMEA_A1301 Brucella melitensis ATCC 23457 hypothetical protein YP_002732983.1 1241314 R 546272 CDS YP_002732984.1 225852751 7677030 complement(1241916..1242677) 1 NC_012441.1 rhomboid family protein 1242677 7677030 BMEA_A1302 Brucella melitensis ATCC 23457 rhomboid family protein YP_002732984.1 1241916 R 546272 CDS YP_002732985.1 225852752 7677031 1243036..1243677 1 NC_012441.1 hypothetical protein 1243677 7677031 BMEA_A1303 Brucella melitensis ATCC 23457 hypothetical protein YP_002732985.1 1243036 D 546272 CDS YP_002732986.1 225852753 7677032 1243921..1244526 1 NC_012441.1 transglutaminase 1244526 7677032 BMEA_A1304 Brucella melitensis ATCC 23457 transglutaminase YP_002732986.1 1243921 D 546272 CDS YP_002732987.1 225852754 7677033 complement(1244605..1245132) 1 NC_012441.1 hypothetical protein 1245132 7677033 BMEA_A1305 Brucella melitensis ATCC 23457 hypothetical protein YP_002732987.1 1244605 R 546272 CDS YP_002732988.1 225852755 7677034 complement(1245196..1245588) 1 NC_012441.1 IS4 transposase 1245588 7677034 BMEA_A1306 Brucella melitensis ATCC 23457 IS4 transposase YP_002732988.1 1245196 R 546272 CDS YP_002732989.1 225852756 7677035 complement(1245585..1245953) 1 NC_012441.1 transposase 1245953 7677035 BMEA_A1307 Brucella melitensis ATCC 23457 transposase YP_002732989.1 1245585 R 546272 CDS YP_002732990.1 225852757 7677036 complement(1246247..1246501) 1 NC_012441.1 hypothetical protein 1246501 7677036 BMEA_A1309 Brucella melitensis ATCC 23457 hypothetical protein YP_002732990.1 1246247 R 546272 CDS YP_002732991.1 225852758 7677037 complement(1246749..1247573) 1 NC_012441.1 serine O-acetyltransferase 1247573 cysE 7677037 cysE Brucella melitensis ATCC 23457 serine O-acetyltransferase YP_002732991.1 1246749 R 546272 CDS YP_002732992.1 225852759 7677038 complement(1247748..1248518) 1 NC_012441.1 alpha/beta hydrolase 1248518 7677038 BMEA_A1311 Brucella melitensis ATCC 23457 alpha/beta hydrolase YP_002732992.1 1247748 R 546272 CDS YP_002732993.1 225852760 7677039 complement(1248552..1249031) 1 NC_012441.1 hypothetical protein 1249031 7677039 BMEA_A1312 Brucella melitensis ATCC 23457 hypothetical protein YP_002732993.1 1248552 R 546272 CDS YP_002732994.1 225852761 7677040 complement(1249405..1249986) 1 NC_012441.1 cold shock-like protein CspG 1249986 7677040 BMEA_A1313 Brucella melitensis ATCC 23457 cold shock-like protein CspG YP_002732994.1 1249405 R 546272 CDS YP_002732995.1 225852762 7677041 complement(1250110..1250247) 1 NC_012441.1 hypothetical protein 1250247 7677041 BMEA_A1314 Brucella melitensis ATCC 23457 hypothetical protein YP_002732995.1 1250110 R 546272 CDS YP_002732996.1 225852763 7677042 complement(1250348..1251376) 1 NC_012441.1 import inner membrane translocase subunit Tim44 1251376 7677042 BMEA_A1315 Brucella melitensis ATCC 23457 import inner membrane translocase subunit Tim44 YP_002732996.1 1250348 R 546272 CDS YP_002732997.1 225852764 7677043 complement(1251538..1253322) 1 NC_012441.1 single-stranded-DNA-specific exonuclease RecJ 1253322 recJ 7677043 recJ Brucella melitensis ATCC 23457 single-stranded-DNA-specific exonuclease RecJ YP_002732997.1 1251538 R 546272 CDS YP_002732998.1 225852765 7677044 complement(1253372..1254433) 1 NC_012441.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1254433 7677044 BMEA_A1317 Brucella melitensis ATCC 23457 D-alanyl-alanine synthetase A YP_002732998.1 1253372 R 546272 CDS YP_002732999.1 225852766 7677045 1254462..1254602 1 NC_012441.1 hypothetical protein 1254602 7677045 BMEA_A1318 Brucella melitensis ATCC 23457 hypothetical protein YP_002732999.1 1254462 D 546272 CDS YP_002733000.1 225852767 7677046 complement(1254736..1255722) 1 NC_012441.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 1255722 glpX 7677046 glpX Brucella melitensis ATCC 23457 fructose 1,6-bisphosphatase II YP_002733000.1 1254736 R 546272 CDS YP_002733001.1 225852768 7677047 complement(1256115..1257434) 1 NC_012441.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1257434 7677047 BMEA_A1320 Brucella melitensis ATCC 23457 homoserine dehydrogenase YP_002733001.1 1256115 R 546272 CDS YP_002733002.1 225852769 7677048 complement(1257570..1258790) 1 NC_012441.1 aminotransferase 1258790 7677048 BMEA_A1321 Brucella melitensis ATCC 23457 aminotransferase YP_002733002.1 1257570 R 546272 CDS YP_002733003.1 225852770 7677049 complement(1258921..1259268) 1 NC_012441.1 hypothetical protein 1259268 7677049 BMEA_A1322 Brucella melitensis ATCC 23457 hypothetical protein YP_002733003.1 1258921 R 546272 CDS YP_002733004.1 225852771 7677050 complement(1259696..1259899) 1 NC_012441.1 hypothetical protein 1259899 7677050 BMEA_A1323 Brucella melitensis ATCC 23457 hypothetical protein YP_002733004.1 1259696 R 546272 CDS YP_002733005.1 225852772 7677054 1261648..1261932 1 NC_012441.1 hypothetical protein 1261932 7677054 BMEA_A1327 Brucella melitensis ATCC 23457 hypothetical protein YP_002733005.1 1261648 D 546272 CDS YP_002733006.1 225852773 7677055 1262255..1262971 1 NC_012441.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1262971 sfsA 7677055 sfsA Brucella melitensis ATCC 23457 sugar fermentation stimulation protein A YP_002733006.1 1262255 D 546272 CDS YP_002733007.1 225852774 7677056 1262971..1263798 1 NC_012441.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1263798 map 7677056 map Brucella melitensis ATCC 23457 methionine aminopeptidase YP_002733007.1 1262971 D 546272 CDS YP_002733008.1 225852775 7677057 1263854..1264603 1 NC_012441.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1264603 7677057 BMEA_A1330 Brucella melitensis ATCC 23457 DNA repair protein RadC YP_002733008.1 1263854 D 546272 CDS YP_002733009.1 225852776 7677058 1264805..1265443 1 NC_012441.1 hypothetical protein 1265443 7677058 BMEA_A1331 Brucella melitensis ATCC 23457 hypothetical protein YP_002733009.1 1264805 D 546272 CDS YP_002733010.1 225852777 7677059 complement(1265732..1266937) 1 NC_012441.1 precorrin-6y C5,15-methyltransferase subunit CbiE 1266937 cbiE 7677059 cbiE Brucella melitensis ATCC 23457 precorrin-6y C5,15-methyltransferase subunit CbiE YP_002733010.1 1265732 R 546272 CDS YP_002733011.1 225852778 7677060 1267011..1268306 1 NC_012441.1 precorrin-3B synthase 1268306 cobG 7677060 cobG Brucella melitensis ATCC 23457 precorrin-3B synthase YP_002733011.1 1267011 D 546272 CDS YP_002733012.1 225852779 7677061 1268316..1268942 1 NC_012441.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 1268942 7677061 BMEA_A1334 Brucella melitensis ATCC 23457 precorrin-8X methylmutase YP_002733012.1 1268316 D 546272 CDS YP_002733013.1 225852780 7677062 1268942..1269676 1 NC_012441.1 catalyzes the formation of precorrin-3 from precorrin-2; precorrin-2 C(20)-methyltransferase 1269676 cobI 7677062 cobI Brucella melitensis ATCC 23457 precorrin-2 C(20)-methyltransferase YP_002733013.1 1268942 D 546272 CDS YP_002733014.1 225852781 7677063 1269622..1271367 1 NC_012441.1 precorrin-3B C(17)-methyltransferase 1271367 cobJ 7677063 cobJ Brucella melitensis ATCC 23457 precorrin-3B C(17)-methyltransferase YP_002733014.1 1269622 D 546272 CDS YP_002733015.1 225852782 7677064 complement(1271405..1271890) 1 NC_012441.1 hypothetical protein 1271890 7677064 BMEA_A1337 Brucella melitensis ATCC 23457 hypothetical protein YP_002733015.1 1271405 R 546272 CDS YP_002733016.1 225852783 7677066 complement(1272915..1273436) 1 NC_012441.1 4-hydroxyphenylacetate 3-monooxygenase reductase subunit 1273436 7677066 BMEA_A1339 Brucella melitensis ATCC 23457 4-hydroxyphenylacetate 3-monooxygenase reductase subunit YP_002733016.1 1272915 R 546272 CDS YP_002733017.1 225852784 7677067 1273485..1274672 1 NC_012441.1 extracellular ligand-binding receptor 1274672 7677067 BMEA_A1340 Brucella melitensis ATCC 23457 extracellular ligand-binding receptor YP_002733017.1 1273485 D 546272 CDS YP_002733018.1 225852785 7677068 complement(1274658..1275641) 1 NC_012441.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1275641 7677068 BMEA_A1341 Brucella melitensis ATCC 23457 cobalamin biosynthesis protein YP_002733018.1 1274658 R 546272 CDS YP_002733019.1 225852786 7677069 complement(1275678..1276676) 1 NC_012441.1 L-threonine-O-3-phosphate decarboxylase 1276676 7677069 BMEA_A1342 Brucella melitensis ATCC 23457 L-threonine-O-3-phosphate decarboxylase YP_002733019.1 1275678 R 546272 CDS YP_002733020.1 225852787 7677070 complement(1276673..1277983) 1 NC_012441.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1277983 cobB 7677070 cobB Brucella melitensis ATCC 23457 cobyrinic acid a,c-diamide synthase YP_002733020.1 1276673 R 546272 CDS YP_002733021.1 225852788 7677071 complement(1277980..1278858) 1 NC_012441.1 uroporphyrin-III C-methyltransferase 1278858 cobA 7677071 cobA Brucella melitensis ATCC 23457 uroporphyrin-III C-methyltransferase YP_002733021.1 1277980 R 546272 CDS YP_002733022.1 225852789 7677072 1278919..1280028 1 NC_012441.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1280028 cbiD 7677072 cbiD Brucella melitensis ATCC 23457 cobalt-precorrin-6A synthase YP_002733022.1 1278919 D 546272 CDS YP_002733023.1 225852790 7677073 1280015..1280761 1 NC_012441.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1280761 7677073 BMEA_A1346 Brucella melitensis ATCC 23457 cobalt-precorrin-6x reductase YP_002733023.1 1280015 D 546272 CDS YP_002733024.1 225852791 7677074 complement(1280750..1281508) 1 NC_012441.1 precorrin-4 C(11)-methyltransferase 1281508 cobM 7677074 cobM Brucella melitensis ATCC 23457 precorrin-4 C(11)-methyltransferase YP_002733024.1 1280750 R 546272 CDS YP_002733025.1 225852792 7677075 complement(1281568..1281963) 1 NC_012441.1 protein CobE 1281963 7677075 BMEA_A1348 Brucella melitensis ATCC 23457 protein CobE YP_002733025.1 1281568 R 546272 CDS YP_002733026.1 225852793 7677076 complement(1281956..1282402) 1 NC_012441.1 hypothetical protein 1282402 7677076 BMEA_A1349 Brucella melitensis ATCC 23457 hypothetical protein YP_002733026.1 1281956 R 546272 CDS YP_002733027.1 225852794 7677077 1282562..1283347 1 NC_012441.1 hypothetical protein 1283347 7677077 BMEA_A1350 Brucella melitensis ATCC 23457 hypothetical protein YP_002733027.1 1282562 D 546272 CDS YP_002733028.1 225852795 7677078 complement(1283344..1283772) 1 NC_012441.1 hypothetical protein 1283772 7677078 BMEA_A1351 Brucella melitensis ATCC 23457 hypothetical protein YP_002733028.1 1283344 R 546272 CDS YP_002733029.1 225852796 7677079 complement(1283772..1284410) 1 NC_012441.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1284410 cobO 7677079 cobO Brucella melitensis ATCC 23457 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002733029.1 1283772 R 546272 CDS YP_002733030.1 225852797 7677080 complement(1284403..1288194) 1 NC_012441.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1288194 cobN 7677080 cobN Brucella melitensis ATCC 23457 cobaltochelatase subunit CobN YP_002733030.1 1284403 R 546272 CDS YP_002733031.1 225852798 7677081 complement(1288194..1289243) 1 NC_012441.1 cobalamin biosynthesis protein CobW 1289243 cobW 7677081 cobW Brucella melitensis ATCC 23457 cobalamin biosynthesis protein CobW YP_002733031.1 1288194 R 546272 CDS YP_002733032.1 225852799 7677082 complement(1289247..1289768) 1 NC_012441.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1289768 7677082 BMEA_A1355 Brucella melitensis ATCC 23457 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_002733032.1 1289247 R 546272 CDS YP_002733033.1 225852800 7677083 complement(1289774..1290490) 1 NC_012441.1 cobalt transporter subunit CbtB 1290490 cbtA 7677083 cbtA Brucella melitensis ATCC 23457 cobalt transporter subunit CbtB YP_002733033.1 1289774 R 546272 CDS YP_002733034.1 225852801 7677084 complement(1290579..1290767) 1 NC_012441.1 cobalt transporter subunit CbtB 1290767 cbtB 7677084 cbtB Brucella melitensis ATCC 23457 cobalt transporter subunit CbtB YP_002733034.1 1290579 R 546272 CDS YP_002733035.1 225852802 7677085 complement(1291081..1292532) 1 NC_012441.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 1292532 cobQ 7677085 cobQ Brucella melitensis ATCC 23457 cobyric acid synthase YP_002733035.1 1291081 R 546272 CDS YP_002733036.1 225852803 7677086 complement(1292543..1292728) 1 NC_012441.1 hypothetical protein 1292728 7677086 BMEA_A1360 Brucella melitensis ATCC 23457 hypothetical protein YP_002733036.1 1292543 R 546272 CDS YP_002733037.1 225852804 7677087 1292808..1293965 1 NC_012441.1 acyl-CoA dehydrogenase 1293965 7677087 BMEA_A1361 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase YP_002733037.1 1292808 D 546272 CDS YP_002733038.1 225852805 7677088 1293997..1294887 1 NC_012441.1 3-hydroxyisobutyrate dehydrogenase 1294887 mmsB 7677088 mmsB Brucella melitensis ATCC 23457 3-hydroxyisobutyrate dehydrogenase YP_002733038.1 1293997 D 546272 CDS YP_002733039.1 225852806 7677089 complement(1295123..1295290) 1 NC_012441.1 hypothetical protein 1295290 7677089 BMEA_A1363 Brucella melitensis ATCC 23457 hypothetical protein YP_002733039.1 1295123 R 546272 CDS YP_002733040.1 225852807 7677090 complement(1295597..1296547) 1 NC_012441.1 HTH-type transcriptional regulator PecT 1296547 7677090 BMEA_A1364 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator PecT YP_002733040.1 1295597 R 546272 CDS YP_002733041.1 225852808 7676281 1296963..1297961 1 NC_012441.1 hypothetical protein 1297961 7676281 BMEA_A1365 Brucella melitensis ATCC 23457 hypothetical protein YP_002733041.1 1296963 D 546272 CDS YP_002733042.1 225852809 7676435 complement(1300875..1301165) 1 NC_012441.1 hypothetical protein 1301165 7676435 BMEA_A1367 Brucella melitensis ATCC 23457 hypothetical protein YP_002733042.1 1300875 R 546272 CDS YP_002733043.1 225852810 7676436 complement(1301272..1303854) 1 NC_012441.1 mechanosensitive ion channel protein MscS 1303854 7676436 BMEA_A1368 Brucella melitensis ATCC 23457 mechanosensitive ion channel protein MscS YP_002733043.1 1301272 R 546272 CDS YP_002733044.1 225852811 7676437 complement(1303978..1304562) 1 NC_012441.1 hypothetical protein 1304562 7676437 BMEA_A1369 Brucella melitensis ATCC 23457 hypothetical protein YP_002733044.1 1303978 R 546272 CDS YP_002733045.1 225852812 7676438 1304614..1307151 1 NC_012441.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1307151 secD 7676438 secD Brucella melitensis ATCC 23457 bifunctional preprotein translocase subunit SecD/SecF YP_002733045.1 1304614 D 546272 CDS YP_002733046.1 225852813 7676439 1307229..1309088 1 NC_012441.1 potassium efflux system protein 1309088 7676439 BMEA_A1371 Brucella melitensis ATCC 23457 potassium efflux system protein YP_002733046.1 1307229 D 546272 CDS YP_002733047.1 225852814 7676440 1309088..1310059 1 NC_012441.1 hypothetical protein 1310059 7676440 BMEA_A1372 Brucella melitensis ATCC 23457 hypothetical protein YP_002733047.1 1309088 D 546272 CDS YP_002733048.1 225852815 7676442 complement(1310937..1311767) 1 NC_012441.1 sulfate ABC transporter permease CysW 1311767 cysW 7676442 cysW Brucella melitensis ATCC 23457 sulfate ABC transporter permease CysW YP_002733048.1 1310937 R 546272 CDS YP_002733049.1 225852816 7676443 complement(1311754..1312620) 1 NC_012441.1 sulfate ABC transporter permease CysT 1312620 cysT 7676443 cysT Brucella melitensis ATCC 23457 sulfate ABC transporter permease CysT YP_002733049.1 1311754 R 546272 CDS YP_002733050.1 225852817 7676444 complement(1312747..1313751) 1 NC_012441.1 sulfate ABC transporter substrate-binding protein 1313751 7676444 BMEA_A1376 Brucella melitensis ATCC 23457 sulfate ABC transporter substrate-binding protein YP_002733050.1 1312747 R 546272 CDS YP_002733051.1 225852818 7676445 complement(1314017..1314202) 1 NC_012441.1 hypothetical protein 1314202 7676445 BMEA_A1378 Brucella melitensis ATCC 23457 hypothetical protein YP_002733051.1 1314017 R 546272 CDS YP_002733052.1 225852819 7676446 complement(1314382..1315950) 1 NC_012441.1 integral membrane protein TerC 1315950 7676446 BMEA_A1379 Brucella melitensis ATCC 23457 integral membrane protein TerC YP_002733052.1 1314382 R 546272 CDS YP_002733053.1 225852820 7676447 complement(1316368..1317030) 1 NC_012441.1 hypothetical protein 1317030 7676447 BMEA_A1380 Brucella melitensis ATCC 23457 hypothetical protein YP_002733053.1 1316368 R 546272 CDS YP_002733054.1 225852821 7676448 1317020..1317133 1 NC_012441.1 hypothetical protein 1317133 7676448 BMEA_A1381 Brucella melitensis ATCC 23457 hypothetical protein YP_002733054.1 1317020 D 546272 CDS YP_002733055.1 225852822 7676450 1317927..1318466 1 NC_012441.1 hypothetical protein 1318466 7676450 BMEA_A1384 Brucella melitensis ATCC 23457 hypothetical protein YP_002733055.1 1317927 D 546272 CDS YP_002733056.1 225852823 7676451 complement(1318600..1319022) 1 NC_012441.1 transporter 1319022 7676451 BMEA_A1385 Brucella melitensis ATCC 23457 transporter YP_002733056.1 1318600 R 546272 CDS YP_002733057.1 225852824 7676452 complement(1319116..1319925) 1 NC_012441.1 short chain dehydrogenase 1319925 7676452 BMEA_A1386 Brucella melitensis ATCC 23457 short chain dehydrogenase YP_002733057.1 1319116 R 546272 CDS YP_002733058.1 225852825 7676453 complement(1319940..1320719) 1 NC_012441.1 hypothetical protein 1320719 7676453 BMEA_A1387 Brucella melitensis ATCC 23457 hypothetical protein YP_002733058.1 1319940 R 546272 CDS YP_002733059.1 225852826 7676454 complement(1320733..1321860) 1 NC_012441.1 monosaccharide-transporting ATPase 1321860 7676454 BMEA_A1388 Brucella melitensis ATCC 23457 monosaccharide-transporting ATPase YP_002733059.1 1320733 R 546272 CDS YP_002733060.1 225852827 7676455 complement(1322147..1323076) 1 NC_012441.1 periplasmic binding protein/LacI transcriptional regulator 1323076 7676455 BMEA_A1389 Brucella melitensis ATCC 23457 periplasmic binding protein/LacI transcriptional regulator YP_002733060.1 1322147 R 546272 CDS YP_002733061.1 225852828 7676456 1323455..1324570 1 NC_012441.1 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase 1324570 7676456 BMEA_A1390 Brucella melitensis ATCC 23457 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase YP_002733061.1 1323455 D 546272 CDS YP_002733062.1 225852829 7676457 complement(1324567..1325343) 1 NC_012441.1 achromobactin transport ATP-binding protein cbrD 1325343 7676457 BMEA_A1391 Brucella melitensis ATCC 23457 achromobactin transport ATP-binding protein cbrD YP_002733062.1 1324567 R 546272 CDS YP_002733063.1 225852830 7676458 complement(1325340..1326341) 1 NC_012441.1 transport system permease 1326341 7676458 BMEA_A1392 Brucella melitensis ATCC 23457 transport system permease YP_002733063.1 1325340 R 546272 CDS YP_002733064.1 225852831 7676459 complement(1326334..1327173) 1 NC_012441.1 periplasmic binding protein 1327173 7676459 BMEA_A1393 Brucella melitensis ATCC 23457 periplasmic binding protein YP_002733064.1 1326334 R 546272 CDS YP_002733065.1 225852832 7676460 complement(1327187..1329049) 1 NC_012441.1 TonB-dependent receptor 1329049 7676460 BMEA_A1394 Brucella melitensis ATCC 23457 TonB-dependent receptor YP_002733065.1 1327187 R 546272 CDS YP_002733066.1 225852833 7676461 complement(1329338..1329493) 1 NC_012441.1 hypothetical protein 1329493 7676461 BMEA_A1396 Brucella melitensis ATCC 23457 hypothetical protein YP_002733066.1 1329338 R 546272 CDS YP_002733067.1 225852834 7676462 complement(1329543..1330655) 1 NC_012441.1 ABC transporter 1330655 7676462 BMEA_A1397 Brucella melitensis ATCC 23457 ABC transporter YP_002733067.1 1329543 R 546272 CDS YP_002733068.1 225852835 7676464 complement(1333423..1334490) 1 NC_012441.1 HlyD family secretion protein 1334490 7676464 BMEA_A1399 Brucella melitensis ATCC 23457 HlyD family secretion protein YP_002733068.1 1333423 R 546272 CDS YP_002733069.1 225852836 7676465 1334470..1334649 1 NC_012441.1 hypothetical protein 1334649 7676465 BMEA_A1400 Brucella melitensis ATCC 23457 hypothetical protein YP_002733069.1 1334470 D 546272 CDS YP_002733070.1 225852837 7676466 complement(1335036..1336331) 1 NC_012441.1 hypothetical protein 1336331 7676466 BMEA_A1401 Brucella melitensis ATCC 23457 hypothetical protein YP_002733070.1 1335036 R 546272 CDS YP_002733071.1 225852838 7676467 complement(1336910..1337086) 1 NC_012441.1 hypothetical protein 1337086 7676467 BMEA_A1402 Brucella melitensis ATCC 23457 hypothetical protein YP_002733071.1 1336910 R 546272 CDS YP_002733072.1 225852839 7676468 1337146..1337448 1 NC_012441.1 UreA, with UreB and UreC, catalyzes the hydrolysis of urea to ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1337448 ureA 7676468 ureA Brucella melitensis ATCC 23457 urease subunit gamma YP_002733072.1 1337146 D 546272 CDS YP_002733073.1 225852840 7676469 1337445..1337978 1 NC_012441.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) does not seem to be involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo; urease subunit beta 1337978 ureB 7676469 ureB Brucella melitensis ATCC 23457 urease subunit beta YP_002733073.1 1337445 D 546272 CDS YP_002733074.1 225852841 7676470 1338018..1339739 1 NC_012441.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1339739 ureC 7676470 ureC Brucella melitensis ATCC 23457 urease subunit alpha YP_002733074.1 1338018 D 546272 CDS YP_002733075.1 225852842 7676471 1339787..1340392 1 NC_012441.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1340392 7676471 BMEA_A1406 Brucella melitensis ATCC 23457 urease accessory protein UreE YP_002733075.1 1339787 D 546272 CDS YP_002733076.1 225852843 7676472 1340364..1341095 1 NC_012441.1 urease accessory protein UreF 1341095 7676472 BMEA_A1407 Brucella melitensis ATCC 23457 urease accessory protein UreF YP_002733076.1 1340364 D 546272 CDS YP_002733077.1 225852844 7676473 1341111..1341749 1 NC_012441.1 urease accessory protein UreG 1341749 ureG 7676473 ureG Brucella melitensis ATCC 23457 urease accessory protein UreG YP_002733077.1 1341111 D 546272 CDS YP_002733078.1 225852845 7676474 1341749..1342657 1 NC_012441.1 urease accessory protein UreD 1342657 7676474 BMEA_A1409 Brucella melitensis ATCC 23457 urease accessory protein UreD YP_002733078.1 1341749 D 546272 CDS YP_002733079.1 225852846 7676475 1342667..1343716 1 NC_012441.1 urea transporter 1343716 yut 7676475 yut Brucella melitensis ATCC 23457 urea transporter YP_002733079.1 1342667 D 546272 CDS YP_002733080.1 225852847 7676476 1343743..1344501 1 NC_012441.1 cobalt ABC transporter periplasmic binding protein CbiN 1344501 7676476 BMEA_A1411 Brucella melitensis ATCC 23457 cobalt ABC transporter periplasmic binding protein CbiN YP_002733080.1 1343743 D 546272 CDS YP_002733081.1 225852848 7676477 1344521..1345156 1 NC_012441.1 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1345156 7676477 BMEA_A1412 Brucella melitensis ATCC 23457 cobalt transport protein CbiM YP_002733081.1 1344521 D 546272 CDS YP_002733082.1 225852849 7676478 1345153..1345779 1 NC_012441.1 CbiL protein 1345779 7676478 BMEA_A1413 Brucella melitensis ATCC 23457 CbiL protein YP_002733082.1 1345153 D 546272 CDS YP_002733083.1 225852850 7676479 1345776..1346540 1 NC_012441.1 cobalt ABC transporter permease CbiQ 1346540 cbiQ 7676479 cbiQ Brucella melitensis ATCC 23457 cobalt ABC transporter permease CbiQ YP_002733083.1 1345776 D 546272 CDS YP_002733084.1 225852851 7676480 1346537..1347256 1 NC_012441.1 cobalt ABC transporter ATP-binding protein 1347256 7676480 BMEA_A1415 Brucella melitensis ATCC 23457 cobalt ABC transporter ATP-binding protein YP_002733084.1 1346537 D 546272 CDS YP_002733085.1 225852852 7676481 complement(1347277..1348089) 1 NC_012441.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1348089 7676481 BMEA_A1416 Brucella melitensis ATCC 23457 camphor resistance protein CrcB YP_002733085.1 1347277 R 546272 CDS YP_002733086.1 225852853 7676482 complement(1348102..1348491) 1 NC_012441.1 CrcB protein 1348491 crcB 7676482 crcB Brucella melitensis ATCC 23457 CrcB protein YP_002733086.1 1348102 R 546272 CDS YP_002733087.1 225852854 7676483 1348760..1349776 1 NC_012441.1 hypothetical protein 1349776 7676483 BMEA_A1418 Brucella melitensis ATCC 23457 hypothetical protein YP_002733087.1 1348760 D 546272 CDS YP_002733088.1 225852855 7676484 complement(1349909..1350343) 1 NC_012441.1 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 1350343 7676484 BMEA_A1419 Brucella melitensis ATCC 23457 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002733088.1 1349909 R 546272 CDS YP_002733089.1 225852856 7676485 1350345..1350482 1 NC_012441.1 hypothetical protein 1350482 7676485 BMEA_A1420 Brucella melitensis ATCC 23457 hypothetical protein YP_002733089.1 1350345 D 546272 CDS YP_002733090.1 225852857 7676486 complement(1350495..1351421) 1 NC_012441.1 phenazine biosynthesis protein PhzF family protein 1351421 7676486 BMEA_A1421 Brucella melitensis ATCC 23457 phenazine biosynthesis protein PhzF family protein YP_002733090.1 1350495 R 546272 CDS YP_002733091.1 225852858 7676487 complement(1351526..1352257) 1 NC_012441.1 NUDIX hydrolase 1352257 7676487 BMEA_A1422 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002733091.1 1351526 R 546272 CDS YP_002733092.1 225852859 7676488 complement(1352277..1353386) 1 NC_012441.1 endonuclease/exonuclease/phosphatase 1353386 7676488 BMEA_A1423 Brucella melitensis ATCC 23457 endonuclease/exonuclease/phosphatase YP_002733092.1 1352277 R 546272 CDS YP_002733093.1 225852860 7676489 1353463..1353978 1 NC_012441.1 BA14K family protein 1353978 7676489 BMEA_A1424 Brucella melitensis ATCC 23457 BA14K family protein YP_002733093.1 1353463 D 546272 CDS YP_002733094.1 225852861 7676490 complement(1354025..1355257) 1 NC_012441.1 GntR family transcriptional regulator 1355257 7676490 BMEA_A1425 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733094.1 1354025 R 546272 CDS YP_002733095.1 225852862 7676491 complement(1355390..1355671) 1 NC_012441.1 hypothetical protein 1355671 7676491 BMEA_A1426 Brucella melitensis ATCC 23457 hypothetical protein YP_002733095.1 1355390 R 546272 CDS YP_002733096.1 225852863 7676492 complement(1355693..1356712) 1 NC_012441.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1356712 ilvC 7676492 ilvC Brucella melitensis ATCC 23457 ketol-acid reductoisomerase YP_002733096.1 1355693 R 546272 CDS YP_002733097.1 225852864 7676493 complement(1356768..1357409) 1 NC_012441.1 TetR family transcriptional regulator 1357409 7676493 BMEA_A1428 Brucella melitensis ATCC 23457 TetR family transcriptional regulator YP_002733097.1 1356768 R 546272 CDS YP_002733098.1 225852865 7676494 1357467..1357622 1 NC_012441.1 hypothetical protein 1357622 7676494 BMEA_A1429 Brucella melitensis ATCC 23457 hypothetical protein YP_002733098.1 1357467 D 546272 CDS YP_002733099.1 225852866 7676495 complement(1357619..1359574) 1 NC_012441.1 potassium transport system protein kup 1359574 7676495 BMEA_A1430 Brucella melitensis ATCC 23457 potassium transport system protein kup YP_002733099.1 1357619 R 546272 CDS YP_002733100.1 225852867 7676496 complement(1359717..1359875) 1 NC_012441.1 hypothetical protein 1359875 7676496 BMEA_A1431 Brucella melitensis ATCC 23457 hypothetical protein YP_002733100.1 1359717 R 546272 CDS YP_002733101.1 225852868 7676497 complement(1359944..1360684) 1 NC_012441.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1360684 7676497 BMEA_A1432 Brucella melitensis ATCC 23457 pyridoxine 5'-phosphate synthase YP_002733101.1 1359944 R 546272 CDS YP_002733102.1 225852869 7676498 1360981..1361382 1 NC_012441.1 hypothetical protein 1361382 7676498 BMEA_A1433 Brucella melitensis ATCC 23457 hypothetical protein YP_002733102.1 1360981 D 546272 CDS YP_002733103.1 225852870 7676499 complement(1361383..1362549) 1 NC_012441.1 hypothetical protein 1362549 7676499 BMEA_A1434 Brucella melitensis ATCC 23457 hypothetical protein YP_002733103.1 1361383 R 546272 CDS YP_002733104.1 225852871 7676500 complement(1362688..1363260) 1 NC_012441.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1363260 ilvN 7676500 ilvN Brucella melitensis ATCC 23457 acetolactate synthase 3 regulatory subunit YP_002733104.1 1362688 R 546272 CDS YP_002733105.1 225852872 7676501 complement(1363279..1365102) 1 NC_012441.1 acetolactate synthase 3 catalytic subunit 1365102 ilvB 7676501 ilvB Brucella melitensis ATCC 23457 acetolactate synthase 3 catalytic subunit YP_002733105.1 1363279 R 546272 CDS YP_002733106.1 225852873 7676502 complement(1365350..1366282) 1 NC_012441.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1366282 miaA 7676502 miaA Brucella melitensis ATCC 23457 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002733106.1 1365350 R 546272 CDS YP_002733107.1 225852874 7676503 1366300..1367199 1 NC_012441.1 phosphoserine phosphatase SerB 1367199 serB 7676503 serB Brucella melitensis ATCC 23457 phosphoserine phosphatase SerB YP_002733107.1 1366300 D 546272 CDS YP_002733108.1 225852875 7676505 complement(1368397..1368540) 1 NC_012441.1 hypothetical protein 1368540 7676505 BMEA_A1440 Brucella melitensis ATCC 23457 hypothetical protein YP_002733108.1 1368397 R 546272 CDS YP_002733109.1 225852876 7676506 complement(1368551..1370125) 1 NC_012441.1 protease Do 1370125 degP 7676506 degP Brucella melitensis ATCC 23457 protease Do YP_002733109.1 1368551 R 546272 CDS YP_002733110.1 225852877 7676507 complement(1370349..1370534) 1 NC_012441.1 hypothetical protein 1370534 7676507 BMEA_A1442 Brucella melitensis ATCC 23457 hypothetical protein YP_002733110.1 1370349 R 546272 CDS YP_002733111.1 225852878 7676508 complement(1370554..1371456) 1 NC_012441.1 HflC protein 1371456 hflC 7676508 hflC Brucella melitensis ATCC 23457 HflC protein YP_002733111.1 1370554 R 546272 CDS YP_002733112.1 225852879 7676509 complement(1371456..1372658) 1 NC_012441.1 HflK protein 1372658 hflK 7676509 hflK Brucella melitensis ATCC 23457 HflK protein YP_002733112.1 1371456 R 546272 CDS YP_002733113.1 225852880 7676510 complement(1372735..1373253) 1 NC_012441.1 dihydrofolate reductase type 3 1373253 7676510 BMEA_A1445 Brucella melitensis ATCC 23457 dihydrofolate reductase type 3 YP_002733113.1 1372735 R 546272 CDS YP_002733114.1 225852881 7676511 complement(1373256..1374050) 1 NC_012441.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1374050 thyA 7676511 thyA Brucella melitensis ATCC 23457 thymidylate synthase YP_002733114.1 1373256 R 546272 CDS YP_002733115.1 225852882 7676512 complement(1374151..1374462) 1 NC_012441.1 hypothetical protein 1374462 7676512 BMEA_A1447 Brucella melitensis ATCC 23457 hypothetical protein YP_002733115.1 1374151 R 546272 CDS YP_002733117.1 225852884 7676663 complement(1376249..1376395) 1 NC_012441.1 hypothetical protein 1376395 7676663 BMEA_A1450 Brucella melitensis ATCC 23457 hypothetical protein YP_002733117.1 1376249 R 546272 CDS YP_002733118.1 225852885 7678146 1376626..1377252 1 NC_012441.1 TetR family transcriptional regulator 1377252 7678146 BMEA_A1451 Brucella melitensis ATCC 23457 TetR family transcriptional regulator YP_002733118.1 1376626 D 546272 CDS YP_002733119.1 225852886 7678147 1377333..1377902 1 NC_012441.1 hypothetical protein 1377902 7678147 BMEA_A1452 Brucella melitensis ATCC 23457 hypothetical protein YP_002733119.1 1377333 D 546272 CDS YP_002733120.1 225852887 7678148 1378015..1378191 1 NC_012441.1 hypothetical protein 1378191 7678148 BMEA_A1453 Brucella melitensis ATCC 23457 hypothetical protein YP_002733120.1 1378015 D 546272 CDS YP_002733121.1 225852888 7678149 1378283..1378483 1 NC_012441.1 hypothetical protein 1378483 7678149 BMEA_A1454 Brucella melitensis ATCC 23457 hypothetical protein YP_002733121.1 1378283 D 546272 CDS YP_002733122.1 225852889 7678150 1378480..1378731 1 NC_012441.1 hypothetical protein 1378731 7678150 BMEA_A1455 Brucella melitensis ATCC 23457 hypothetical protein YP_002733122.1 1378480 D 546272 CDS YP_002733123.1 225852890 7678151 complement(1378759..1382502) 1 NC_012441.1 AsmA family protein 1382502 7678151 BMEA_A1456 Brucella melitensis ATCC 23457 AsmA family protein YP_002733123.1 1378759 R 546272 CDS YP_002733124.1 225852891 7678152 complement(1382557..1382697) 1 NC_012441.1 hypothetical protein 1382697 7678152 BMEA_A1457 Brucella melitensis ATCC 23457 hypothetical protein YP_002733124.1 1382557 R 546272 CDS YP_002733125.1 225852892 7678153 complement(1382694..1384100) 1 NC_012441.1 hypothetical protein 1384100 7678153 BMEA_A1458 Brucella melitensis ATCC 23457 hypothetical protein YP_002733125.1 1382694 R 546272 CDS YP_002733126.1 225852893 7678154 complement(1384125..1384634) 1 NC_012441.1 hypothetical protein 1384634 7678154 BMEA_A1459 Brucella melitensis ATCC 23457 hypothetical protein YP_002733126.1 1384125 R 546272 CDS YP_002733127.1 225852894 7678155 1384754..1385830 1 NC_012441.1 serine/threonine protein kinase 1385830 7678155 BMEA_A1460 Brucella melitensis ATCC 23457 serine/threonine protein kinase YP_002733127.1 1384754 D 546272 CDS YP_002733128.1 225852895 7678156 1385889..1388465 1 NC_012441.1 ATP-dependent DNA helicase PcrA 1388465 7678156 BMEA_A1461 Brucella melitensis ATCC 23457 ATP-dependent DNA helicase PcrA YP_002733128.1 1385889 D 546272 CDS YP_002733129.1 225852896 7678157 complement(1388539..1389036) 1 NC_012441.1 CreA family protein 1389036 7678157 BMEA_A1462 Brucella melitensis ATCC 23457 CreA family protein YP_002733129.1 1388539 R 546272 CDS YP_002733130.1 225852897 7678158 complement(1389101..1389790) 1 NC_012441.1 phosphonate metabolism protein 1389790 7678158 BMEA_A1463 Brucella melitensis ATCC 23457 phosphonate metabolism protein YP_002733130.1 1389101 R 546272 CDS YP_002733131.1 225852898 7678159 1389899..1390489 1 NC_012441.1 electron transport protein SCO1/SenC 1390489 7678159 BMEA_A1464 Brucella melitensis ATCC 23457 electron transport protein SCO1/SenC YP_002733131.1 1389899 D 546272 CDS YP_002733132.1 225852899 7678160 1390527..1391384 1 NC_012441.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1391384 7678160 BMEA_A1465 Brucella melitensis ATCC 23457 50S ribosomal protein L11 methyltransferase YP_002733132.1 1390527 D 546272 CDS YP_002733133.1 225852900 7678161 1391461..1393287 1 NC_012441.1 peptidase M24 1393287 7678161 BMEA_A1466 Brucella melitensis ATCC 23457 peptidase M24 YP_002733133.1 1391461 D 546272 CDS YP_002733134.1 225852901 7678162 complement(1393288..1393992) 1 NC_012441.1 hypothetical protein 1393992 7678162 BMEA_A1467 Brucella melitensis ATCC 23457 hypothetical protein YP_002733134.1 1393288 R 546272 CDS YP_002733135.1 225852902 7678163 complement(1393992..1396151) 1 NC_012441.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1396151 ligA 7678163 ligA Brucella melitensis ATCC 23457 NAD-dependent DNA ligase LigA YP_002733135.1 1393992 R 546272 CDS YP_002733136.1 225852903 7678164 complement(1396337..1398016) 1 NC_012441.1 DNA repair protein RecN 1398016 recN 7678164 recN Brucella melitensis ATCC 23457 DNA repair protein RecN YP_002733136.1 1396337 R 546272 CDS YP_002733137.1 225852904 7678165 complement(1398029..1398892) 1 NC_012441.1 outer membrane assembly lipoprotein YfiO 1398892 yfiO 7678165 yfiO Brucella melitensis ATCC 23457 outer membrane assembly lipoprotein YfiO YP_002733137.1 1398029 R 546272 CDS YP_002733138.1 225852905 7678166 1398994..1399239 1 NC_012441.1 hypothetical protein 1399239 7678166 BMEA_A1471 Brucella melitensis ATCC 23457 hypothetical protein YP_002733138.1 1398994 D 546272 CDS YP_002733139.1 225852906 7678167 complement(1399299..1400159) 1 NC_012441.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1400159 lpxC 7678167 lpxC Brucella melitensis ATCC 23457 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002733139.1 1399299 R 546272 CDS YP_002733140.1 225852907 7678168 complement(1400699..1402399) 1 NC_012441.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1402399 ftsZ 7678168 ftsZ Brucella melitensis ATCC 23457 cell division protein FtsZ YP_002733140.1 1400699 R 546272 CDS YP_002733141.1 225852908 7678169 complement(1402496..1403818) 1 NC_012441.1 cell division protein FtsA 1403818 ftsA 7678169 ftsA Brucella melitensis ATCC 23457 cell division protein FtsA YP_002733141.1 1402496 R 546272 CDS YP_002733142.1 225852909 7678170 complement(1403815..1404681) 1 NC_012441.1 cell division protein FtsQ 1404681 7678170 BMEA_A1475 Brucella melitensis ATCC 23457 cell division protein FtsQ YP_002733142.1 1403815 R 546272 CDS YP_002733143.1 225852910 7678171 complement(1404738..1405664) 1 NC_012441.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1405664 7678171 BMEA_A1476 Brucella melitensis ATCC 23457 D-alanine--D-alanine ligase YP_002733143.1 1404738 R 546272 CDS YP_002733144.1 225852911 7678172 complement(1405907..1406875) 1 NC_012441.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1406875 murB 7678172 murB Brucella melitensis ATCC 23457 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002733144.1 1405907 R 546272 CDS YP_002733145.1 225852912 7678173 complement(1406875..1408290) 1 NC_012441.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1408290 murC 7678173 murC Brucella melitensis ATCC 23457 UDP-N-acetylmuramate--L-alanine ligase YP_002733145.1 1406875 R 546272 CDS YP_002733146.1 225852913 7678174 complement(1408287..1409426) 1 NC_012441.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 1409426 murG 7678174 murG Brucella melitensis ATCC 23457 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002733146.1 1408287 R 546272 CDS YP_002733147.1 225852914 7678175 complement(1409653..1410810) 1 NC_012441.1 cell division protein FtsW 1410810 ftsW 7678175 ftsW Brucella melitensis ATCC 23457 cell division protein FtsW YP_002733147.1 1409653 R 546272 CDS YP_002733148.1 225852915 7678176 complement(1410810..1412213) 1 NC_012441.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1412213 murD 7678176 murD Brucella melitensis ATCC 23457 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002733148.1 1410810 R 546272 CDS YP_002733149.1 225852916 7678177 complement(1412226..1413308) 1 NC_012441.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1413308 mraY 7678177 mraY Brucella melitensis ATCC 23457 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002733149.1 1412226 R 546272 CDS YP_002733150.1 225852917 7678178 complement(1413335..1414780) 1 NC_012441.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1414780 murF 7678178 murF Brucella melitensis ATCC 23457 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002733150.1 1413335 R 546272 CDS YP_002733151.1 225852918 7678179 complement(1414777..1416243) 1 NC_012441.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1416243 murE 7678179 murE Brucella melitensis ATCC 23457 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002733151.1 1414777 R 546272 CDS YP_002733152.1 225852919 7678180 complement(1416304..1418127) 1 NC_012441.1 penicillin-binding protein 2 1418127 7678180 BMEA_A1485 Brucella melitensis ATCC 23457 penicillin-binding protein 2 YP_002733152.1 1416304 R 546272 CDS YP_002733153.1 225852920 7678181 complement(1418118..1418531) 1 NC_012441.1 hypothetical protein 1418531 7678181 BMEA_A1486 Brucella melitensis ATCC 23457 hypothetical protein YP_002733153.1 1418118 R 546272 CDS YP_002733154.1 225852921 7678182 complement(1418536..1419576) 1 NC_012441.1 S-adenosyl-methyltransferase MraW 1419576 mraW 7678182 mraW Brucella melitensis ATCC 23457 S-adenosyl-methyltransferase MraW YP_002733154.1 1418536 R 546272 CDS YP_002733155.1 225852922 7678183 1419554..1419823 1 NC_012441.1 hypothetical protein 1419823 7678183 BMEA_A1488 Brucella melitensis ATCC 23457 hypothetical protein YP_002733155.1 1419554 D 546272 CDS YP_002733156.1 225852923 7678184 1420018..1421388 1 NC_012441.1 manganese transport protein MntH 1421388 7678184 BMEA_A1489 Brucella melitensis ATCC 23457 manganese transport protein MntH YP_002733156.1 1420018 D 546272 CDS YP_002733157.1 225852924 7678186 complement(1422090..1422734) 1 NC_012441.1 lytic transglycosylase 1422734 7678186 BMEA_A1493 Brucella melitensis ATCC 23457 lytic transglycosylase YP_002733157.1 1422090 R 546272 CDS YP_002733158.1 225852925 7678187 complement(1423075..1423881) 1 NC_012441.1 N-acetylmuramoyl-L-alanine amidase family 2 protein 1423881 7678187 BMEA_A1494 Brucella melitensis ATCC 23457 N-acetylmuramoyl-L-alanine amidase family 2 protein YP_002733158.1 1423075 R 546272 CDS YP_002733159.1 225852926 7678188 complement(1423878..1424588) 1 NC_012441.1 DnaJ-like protein djlA 1424588 7678188 BMEA_A1495 Brucella melitensis ATCC 23457 DnaJ-like protein djlA YP_002733159.1 1423878 R 546272 CDS YP_002733160.1 225852927 7678189 complement(1424708..1425112) 1 NC_012441.1 hypothetical protein 1425112 7678189 BMEA_A1496 Brucella melitensis ATCC 23457 hypothetical protein YP_002733160.1 1424708 R 546272 CDS YP_002733161.1 225852928 7678190 1425416..1426249 1 NC_012441.1 family 25 glycosyl hydrolase 1426249 7678190 BMEA_A1497 Brucella melitensis ATCC 23457 family 25 glycosyl hydrolase YP_002733161.1 1425416 D 546272 CDS YP_002733162.1 225852929 7678191 1426361..1427602 1 NC_012441.1 lytic murein transglycosylase 1427602 7678191 BMEA_A1498 Brucella melitensis ATCC 23457 lytic murein transglycosylase YP_002733162.1 1426361 D 546272 CDS YP_002733163.1 225852930 7678192 1427664..1428599 1 NC_012441.1 auxin efflux carrier protein 1428599 7678192 BMEA_A1499 Brucella melitensis ATCC 23457 auxin efflux carrier protein YP_002733163.1 1427664 D 546272 CDS YP_002733164.1 225852931 7678193 complement(1429034..1429945) 1 NC_012441.1 5,10-methylenetetrahydrofolate reductase 1429945 metF 7678193 metF Brucella melitensis ATCC 23457 5,10-methylenetetrahydrofolate reductase YP_002733164.1 1429034 R 546272 CDS YP_002733165.1 225852932 7678194 complement(1429991..1431016) 1 NC_012441.1 methyltransferase type 11 1431016 7678194 BMEA_A1501 Brucella melitensis ATCC 23457 methyltransferase type 11 YP_002733165.1 1429991 R 546272 CDS YP_002733166.1 225852933 7678195 1431136..1431459 1 NC_012441.1 hypothetical protein 1431459 7678195 BMEA_A1502 Brucella melitensis ATCC 23457 hypothetical protein YP_002733166.1 1431136 D 546272 CDS YP_002733167.1 225852934 7678196 complement(1431514..1432839) 1 NC_012441.1 metabolite:proton symporter family protein 1432839 cit 7678196 cit Brucella melitensis ATCC 23457 metabolite:proton symporter family protein YP_002733167.1 1431514 R 546272 CDS YP_002733168.1 225852935 7678197 1432847..1433101 1 NC_012441.1 hypothetical protein 1433101 7678197 BMEA_A1504 Brucella melitensis ATCC 23457 hypothetical protein YP_002733168.1 1432847 D 546272 CDS YP_002733169.1 225852936 7678198 complement(1433275..1433940) 1 NC_012441.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1433940 7678198 BMEA_A1505 Brucella melitensis ATCC 23457 trans-aconitate 2-methyltransferase YP_002733169.1 1433275 R 546272 CDS YP_002733170.1 225852937 7678199 complement(1434114..1435763) 1 NC_012441.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1435763 7678199 BMEA_A1506 Brucella melitensis ATCC 23457 putative ABC transporter ATP-binding protein YP_002733170.1 1434114 R 546272 CDS YP_002733171.1 225852938 7678200 complement(1435843..1436022) 1 NC_012441.1 hypothetical protein 1436022 7678200 BMEA_A1507 Brucella melitensis ATCC 23457 hypothetical protein YP_002733171.1 1435843 R 546272 CDS YP_002733172.1 225852939 7678201 1436259..1437203 1 NC_012441.1 lysophospholipase L2 1437203 7678201 BMEA_A1508 Brucella melitensis ATCC 23457 lysophospholipase L2 YP_002733172.1 1436259 D 546272 CDS YP_002733173.1 225852940 7678203 complement(1438000..1438686) 1 NC_012441.1 hypothetical protein 1438686 7678203 BMEA_A1510 Brucella melitensis ATCC 23457 hypothetical protein YP_002733173.1 1438000 R 546272 CDS YP_002733174.1 225852941 7678204 1439037..1440284 1 NC_012441.1 biphenyl dioxygenase subunit alpha 1440284 7678204 BMEA_A1511 Brucella melitensis ATCC 23457 biphenyl dioxygenase subunit alpha YP_002733174.1 1439037 D 546272 CDS YP_002733175.1 225852942 7678205 1440318..1441436 1 NC_012441.1 ferredoxin 1441436 7678205 BMEA_A1512 Brucella melitensis ATCC 23457 ferredoxin YP_002733175.1 1440318 D 546272 CDS YP_002733176.1 225852943 7678206 complement(1441439..1441660) 1 NC_012441.1 PhnA protein 1441660 7678206 BMEA_A1513 Brucella melitensis ATCC 23457 PhnA protein YP_002733176.1 1441439 R 546272 CDS YP_002733177.1 225852944 7678207 1441798..1442427 1 NC_012441.1 nicotinamidase 1442427 7678207 BMEA_A1514 Brucella melitensis ATCC 23457 nicotinamidase YP_002733177.1 1441798 D 546272 CDS YP_002733178.1 225852945 7678208 complement(1442424..1443485) 1 NC_012441.1 hypothetical protein 1443485 7678208 BMEA_A1515 Brucella melitensis ATCC 23457 hypothetical protein YP_002733178.1 1442424 R 546272 CDS YP_002733179.1 225852946 7678209 1443832..1444098 1 NC_012441.1 hypothetical protein 1444098 7678209 BMEA_A1516 Brucella melitensis ATCC 23457 hypothetical protein YP_002733179.1 1443832 D 546272 CDS YP_002733180.1 225852947 7678210 complement(1444054..1444233) 1 NC_012441.1 hypothetical protein 1444233 7678210 BMEA_A1517 Brucella melitensis ATCC 23457 hypothetical protein YP_002733180.1 1444054 R 546272 CDS YP_002733181.1 225852948 7678211 complement(1444296..1445399) 1 NC_012441.1 penicillin acylase 1445399 7678211 BMEA_A1518 Brucella melitensis ATCC 23457 penicillin acylase YP_002733181.1 1444296 R 546272 CDS YP_002733182.1 225852949 7678212 1445675..1446478 1 NC_012441.1 hypothetical protein 1446478 7678212 BMEA_A1519 Brucella melitensis ATCC 23457 hypothetical protein YP_002733182.1 1445675 D 546272 CDS YP_002733183.1 225852950 7678213 complement(1446682..1446801) 1 NC_012441.1 hypothetical protein 1446801 7678213 BMEA_A1520 Brucella melitensis ATCC 23457 hypothetical protein YP_002733183.1 1446682 R 546272 CDS YP_002733184.1 225852951 7678214 1447085..1447270 1 NC_012441.1 hypothetical protein 1447270 7678214 BMEA_A1521 Brucella melitensis ATCC 23457 hypothetical protein YP_002733184.1 1447085 D 546272 CDS YP_002733185.1 225852952 7678215 complement(1447324..1447551) 1 NC_012441.1 hypothetical protein 1447551 7678215 BMEA_A1522 Brucella melitensis ATCC 23457 hypothetical protein YP_002733185.1 1447324 R 546272 CDS YP_002733186.1 225852953 7678216 1447678..1448031 1 NC_012441.1 hypothetical protein 1448031 7678216 BMEA_A1523 Brucella melitensis ATCC 23457 hypothetical protein YP_002733186.1 1447678 D 546272 CDS YP_002733187.1 225852954 7678217 complement(1448192..1448764) 1 NC_012441.1 hypothetical protein 1448764 7678217 BMEA_A1524 Brucella melitensis ATCC 23457 hypothetical protein YP_002733187.1 1448192 R 546272 CDS YP_002733188.1 225852955 7678218 1449000..1449494 1 NC_012441.1 phage integrase 1449494 7678218 BMEA_A1525 Brucella melitensis ATCC 23457 phage integrase YP_002733188.1 1449000 D 546272 CDS YP_002733189.1 225852956 7678220 1449912..1450664 1 NC_012441.1 hypothetical protein 1450664 7678220 BMEA_A1527 Brucella melitensis ATCC 23457 hypothetical protein YP_002733189.1 1449912 D 546272 CDS YP_002733190.1 225852957 7678221 complement(1450838..1451182) 1 NC_012441.1 hypothetical protein 1451182 7678221 BMEA_A1528 Brucella melitensis ATCC 23457 hypothetical protein YP_002733190.1 1450838 R 546272 CDS YP_002733191.1 225852958 7678222 complement(1451426..1451884) 1 NC_012441.1 hypothetical protein 1451884 7678222 BMEA_A1529 Brucella melitensis ATCC 23457 hypothetical protein YP_002733191.1 1451426 R 546272 CDS YP_002733192.1 225852959 7678223 complement(1452076..1452366) 1 NC_012441.1 hypothetical protein 1452366 7678223 BMEA_A1530 Brucella melitensis ATCC 23457 hypothetical protein YP_002733192.1 1452076 R 546272 CDS YP_002733193.1 225852960 7678224 complement(1452390..1454408) 1 NC_012441.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1454408 rpoD 7678224 rpoD Brucella melitensis ATCC 23457 RNA polymerase sigma factor RpoD YP_002733193.1 1452390 R 546272 CDS YP_002733194.1 225852961 7678225 complement(1454439..1454594) 1 NC_012441.1 hypothetical protein 1454594 7678225 BMEA_A1532 Brucella melitensis ATCC 23457 hypothetical protein YP_002733194.1 1454439 R 546272 CDS YP_002733195.1 225852962 7678226 complement(1454876..1456843) 1 NC_012441.1 synthesizes RNA primers at the replication forks; DNA primase 1456843 dnaG 7678226 dnaG Brucella melitensis ATCC 23457 DNA primase YP_002733195.1 1454876 R 546272 CDS YP_002733196.1 225852963 7678308 1457213..1458889 1 NC_012441.1 Na+ cotransporter 1458889 7678308 BMEA_A1534 Brucella melitensis ATCC 23457 Na+ cotransporter YP_002733196.1 1457213 D 546272 CDS YP_002733197.1 225852964 7677170 complement(1458956..1459408) 1 NC_012441.1 GatB/Yqey domain-containing protein 1459408 7677170 BMEA_A1535 Brucella melitensis ATCC 23457 GatB/Yqey domain-containing protein YP_002733197.1 1458956 R 546272 CDS YP_002733198.1 225852965 7677171 1459788..1461011 1 NC_012441.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1461011 carA 7677171 carA Brucella melitensis ATCC 23457 carbamoyl phosphate synthase small subunit YP_002733198.1 1459788 D 546272 CDS YP_002733199.1 225852966 7677172 complement(1461183..1462109) 1 NC_012441.1 hypothetical protein 1462109 7677172 BMEA_A1538 Brucella melitensis ATCC 23457 hypothetical protein YP_002733199.1 1461183 R 546272 CDS YP_002733200.1 225852967 7677173 complement(1462226..1462744) 1 NC_012441.1 hypothetical protein 1462744 7677173 BMEA_A1539 Brucella melitensis ATCC 23457 hypothetical protein YP_002733200.1 1462226 R 546272 CDS YP_002733201.1 225852968 7677174 1462830..1463534 1 NC_012441.1 response regulator receiver protein 1463534 7677174 BMEA_A1540 Brucella melitensis ATCC 23457 response regulator receiver protein YP_002733201.1 1462830 D 546272 CDS YP_002733202.1 225852969 7677175 1463864..1467352 1 NC_012441.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1467352 carB 7677175 carB Brucella melitensis ATCC 23457 carbamoyl phosphate synthase large subunit YP_002733202.1 1463864 D 546272 CDS YP_002733203.1 225852970 7677176 1467673..1468011 1 NC_012441.1 hypothetical protein 1468011 7677176 BMEA_A1542 Brucella melitensis ATCC 23457 hypothetical protein YP_002733203.1 1467673 D 546272 CDS YP_002733204.1 225852971 7677177 complement(1468069..1469934) 1 NC_012441.1 ABC transporter 1469934 7677177 BMEA_A1543 Brucella melitensis ATCC 23457 ABC transporter YP_002733204.1 1468069 R 546272 CDS YP_002733205.1 225852972 7677178 1470124..1470585 1 NC_012441.1 NUDIX hydrolase 1470585 7677178 BMEA_A1544 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002733205.1 1470124 D 546272 CDS YP_002733206.1 225852973 7677179 1470778..1470987 1 NC_012441.1 hypothetical protein 1470987 7677179 BMEA_A1545 Brucella melitensis ATCC 23457 hypothetical protein YP_002733206.1 1470778 D 546272 CDS YP_002733207.1 225852974 7677180 complement(1471116..1471727) 1 NC_012441.1 protein GstA 1471727 7677180 BMEA_A1546 Brucella melitensis ATCC 23457 protein GstA YP_002733207.1 1471116 R 546272 CDS YP_002733208.1 225852975 7677181 1471977..1473179 1 NC_012441.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1473179 7677181 BMEA_A1547 Brucella melitensis ATCC 23457 aspartate aminotransferase YP_002733208.1 1471977 D 546272 CDS YP_002733209.1 225852976 7677182 1473381..1473596 1 NC_012441.1 hypothetical protein 1473596 7677182 BMEA_A1548 Brucella melitensis ATCC 23457 hypothetical protein YP_002733209.1 1473381 D 546272 CDS YP_002733210.1 225852977 7677183 complement(1473648..1474553) 1 NC_012441.1 hypothetical protein 1474553 7677183 BMEA_A1549 Brucella melitensis ATCC 23457 hypothetical protein YP_002733210.1 1473648 R 546272 CDS YP_002733211.1 225852978 7677184 complement(1474624..1475598) 1 NC_012441.1 thioredoxin-disulfide reductase 1475598 trxB 7677184 trxB Brucella melitensis ATCC 23457 thioredoxin-disulfide reductase YP_002733211.1 1474624 R 546272 CDS YP_002733212.1 225852979 7677185 1475920..1477320 1 NC_012441.1 cation transporter 1477320 7677185 BMEA_A1551 Brucella melitensis ATCC 23457 cation transporter YP_002733212.1 1475920 D 546272 CDS YP_002733213.1 225852980 7677186 1477327..1477491 1 NC_012441.1 hypothetical protein 1477491 7677186 BMEA_A1552 Brucella melitensis ATCC 23457 hypothetical protein YP_002733213.1 1477327 D 546272 CDS YP_002733214.1 225852981 7677187 1477578..1478048 1 NC_012441.1 leucine-responsive regulatory protein 1478048 7677187 BMEA_A1553 Brucella melitensis ATCC 23457 leucine-responsive regulatory protein YP_002733214.1 1477578 D 546272 CDS YP_002733215.1 225852982 7677188 complement(1478055..1479119) 1 NC_012441.1 lipopolysaccharide core biosynthesis mannosyltransferase lpcC 1479119 7677188 BMEA_A1554 Brucella melitensis ATCC 23457 lipopolysaccharide core biosynthesis mannosyltransferase lpcC YP_002733215.1 1478055 R 546272 CDS YP_002733216.1 225852983 7677189 complement(1479126..1479599) 1 NC_012441.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1479599 greA 7677189 greA Brucella melitensis ATCC 23457 transcription elongation factor GreA YP_002733216.1 1479126 R 546272 CDS YP_002733217.1 225852984 7677190 complement(1479868..1480923) 1 NC_012441.1 hypothetical protein 1480923 7677190 BMEA_A1556 Brucella melitensis ATCC 23457 hypothetical protein YP_002733217.1 1479868 R 546272 CDS YP_002733218.1 225852985 7677191 complement(1480913..1481101) 1 NC_012441.1 hypothetical protein 1481101 7677191 BMEA_A1557 Brucella melitensis ATCC 23457 hypothetical protein YP_002733218.1 1480913 R 546272 CDS YP_002733219.1 225852986 7677192 1481079..1481990 1 NC_012441.1 hypothetical protein 1481990 7677192 BMEA_A1558 Brucella melitensis ATCC 23457 hypothetical protein YP_002733219.1 1481079 D 546272 CDS YP_002733220.1 225852987 7677193 complement(1481995..1482345) 1 NC_012441.1 hypothetical protein 1482345 7677193 BMEA_A1559 Brucella melitensis ATCC 23457 hypothetical protein YP_002733220.1 1481995 R 546272 CDS YP_002733221.1 225852988 7677194 1482623..1483534 1 NC_012441.1 extensin family protein 1483534 7677194 BMEA_A1560 Brucella melitensis ATCC 23457 extensin family protein YP_002733221.1 1482623 D 546272 CDS YP_002733222.1 225852989 7677195 complement(1483667..1484056) 1 NC_012441.1 thioesterase superfamily protein 1484056 7677195 BMEA_A1561 Brucella melitensis ATCC 23457 thioesterase superfamily protein YP_002733222.1 1483667 R 546272 CDS YP_002733223.1 225852990 7677197 1484984..1487806 1 NC_012441.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1487806 uvrB 7677197 uvrB Brucella melitensis ATCC 23457 excinuclease ABC subunit B YP_002733223.1 1484984 D 546272 CDS YP_002733224.1 225852991 7677199 1489236..1489451 1 NC_012441.1 hypothetical protein 1489451 7677199 BMEA_A1565 Brucella melitensis ATCC 23457 hypothetical protein YP_002733224.1 1489236 D 546272 CDS YP_002733225.1 225852992 7677200 1489467..1489790 1 NC_012441.1 hypothetical protein 1489790 7677200 BMEA_A1566 Brucella melitensis ATCC 23457 hypothetical protein YP_002733225.1 1489467 D 546272 CDS YP_002733226.1 225852993 7677201 1489868..1490374 1 NC_012441.1 hypothetical protein 1490374 7677201 BMEA_A1567 Brucella melitensis ATCC 23457 hypothetical protein YP_002733226.1 1489868 D 546272 CDS YP_002733227.1 225852994 7677202 complement(1490433..1491089) 1 NC_012441.1 beta-lactamase domain-containing protein 1491089 7677202 BMEA_A1568 Brucella melitensis ATCC 23457 beta-lactamase domain-containing protein YP_002733227.1 1490433 R 546272 CDS YP_002733228.1 225852995 7677203 complement(1491303..1491584) 1 NC_012441.1 hypothetical protein 1491584 7677203 BMEA_A1569 Brucella melitensis ATCC 23457 hypothetical protein YP_002733228.1 1491303 R 546272 CDS YP_002733229.1 225852996 7677204 1491759..1492067 1 NC_012441.1 hypothetical protein 1492067 7677204 BMEA_A1570 Brucella melitensis ATCC 23457 hypothetical protein YP_002733229.1 1491759 D 546272 CDS YP_002733230.1 225852997 7677205 1492051..1492644 1 NC_012441.1 HTH-type transcriptional regulator PetP 1492644 7677205 BMEA_A1572 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator PetP YP_002733230.1 1492051 D 546272 CDS YP_002733231.1 225852998 7677206 1492726..1493451 1 NC_012441.1 protein PetR 1493451 7677206 BMEA_A1573 Brucella melitensis ATCC 23457 protein PetR YP_002733231.1 1492726 D 546272 CDS YP_002733232.1 225852999 7677207 1493595..1494938 1 NC_012441.1 integral membrane sensor signal transduction histidine kinase 1494938 7677207 BMEA_A1574 Brucella melitensis ATCC 23457 integral membrane sensor signal transduction histidine kinase YP_002733232.1 1493595 D 546272 CDS YP_002733233.1 225853000 7677208 1494942..1495070 1 NC_012441.1 hypothetical protein 1495070 7677208 BMEA_A1575 Brucella melitensis ATCC 23457 hypothetical protein YP_002733233.1 1494942 D 546272 CDS YP_002733234.1 225853001 7677209 complement(1495370..1495717) 1 NC_012441.1 export-related chaperone CsaA 1495717 csaA 7677209 csaA Brucella melitensis ATCC 23457 export-related chaperone CsaA YP_002733234.1 1495370 R 546272 CDS YP_002733235.1 225853002 7677210 complement(1495857..1496357) 1 NC_012441.1 hypothetical protein 1496357 7677210 BMEA_A1578 Brucella melitensis ATCC 23457 hypothetical protein YP_002733235.1 1495857 R 546272 CDS YP_002733236.1 225853003 7677211 complement(1496419..1496511) 1 NC_012441.1 hypothetical protein 1496511 7677211 BMEA_A1579 Brucella melitensis ATCC 23457 hypothetical protein YP_002733236.1 1496419 R 546272 CDS YP_002733237.1 225853004 7677212 complement(1496786..1497106) 1 NC_012441.1 hypothetical protein 1497106 7677212 BMEA_A1580 Brucella melitensis ATCC 23457 hypothetical protein YP_002733237.1 1496786 R 546272 CDS YP_002733238.1 225853005 7677213 complement(1497124..1497264) 1 NC_012441.1 hypothetical protein 1497264 7677213 BMEA_A1581 Brucella melitensis ATCC 23457 hypothetical protein YP_002733238.1 1497124 R 546272 CDS YP_002733239.1 225853006 7677214 1497291..1498136 1 NC_012441.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1498136 lgt 7677214 lgt Brucella melitensis ATCC 23457 prolipoprotein diacylglyceryl transferase YP_002733239.1 1497291 D 546272 CDS YP_002733240.1 225853007 7677215 1498129..1499226 1 NC_012441.1 hypothetical protein 1499226 7677215 BMEA_A1583 Brucella melitensis ATCC 23457 hypothetical protein YP_002733240.1 1498129 D 546272 CDS YP_002733241.1 225853008 7677216 1499406..1500257 1 NC_012441.1 hypothetical protein 1500257 7677216 BMEA_A1584 Brucella melitensis ATCC 23457 hypothetical protein YP_002733241.1 1499406 D 546272 CDS YP_002733242.1 225853009 7677217 1500370..1501521 1 NC_012441.1 Xaa-Pro dipeptidase 1501521 7677217 BMEA_A1585 Brucella melitensis ATCC 23457 Xaa-Pro dipeptidase YP_002733242.1 1500370 D 546272 CDS YP_002733243.1 225853010 7677218 1501575..1502129 1 NC_012441.1 hypothetical protein 1502129 7677218 BMEA_A1586 Brucella melitensis ATCC 23457 hypothetical protein YP_002733243.1 1501575 D 546272 CDS YP_002733244.1 225853011 7677219 1502468..1503400 1 NC_012441.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1503400 prs 7677219 prs Brucella melitensis ATCC 23457 ribose-phosphate pyrophosphokinase YP_002733244.1 1502468 D 546272 CDS YP_002733245.1 225853012 7677220 complement(1503548..1505089) 1 NC_012441.1 hypothetical protein 1505089 7677220 BMEA_A1588 Brucella melitensis ATCC 23457 hypothetical protein YP_002733245.1 1503548 R 546272 CDS YP_002733246.1 225853013 7677221 1505523..1505693 1 NC_012441.1 hypothetical protein 1505693 7677221 BMEA_A1589 Brucella melitensis ATCC 23457 hypothetical protein YP_002733246.1 1505523 D 546272 CDS YP_002733247.1 225853014 7677222 1505781..1506404 1 NC_012441.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1506404 7677222 BMEA_A1590 Brucella melitensis ATCC 23457 50S ribosomal protein L25/general stress protein Ctc YP_002733247.1 1505781 D 546272 CDS YP_002733248.1 225853015 7677223 1506433..1507185 1 NC_012441.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1507185 pth 7677223 pth Brucella melitensis ATCC 23457 peptidyl-tRNA hydrolase YP_002733248.1 1506433 D 546272 CDS YP_002733249.1 225853016 7677224 1507273..1508376 1 NC_012441.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1508376 ychF 7677224 ychF Brucella melitensis ATCC 23457 GTP-dependent nucleic acid-binding protein EngD YP_002733249.1 1507273 D 546272 CDS YP_002733250.1 225853017 7677225 1508438..1508938 1 NC_012441.1 MaoC domain-containing protein dehydratase 1508938 7677225 BMEA_A1593 Brucella melitensis ATCC 23457 MaoC domain-containing protein dehydratase YP_002733250.1 1508438 D 546272 CDS YP_002733251.1 225853018 7677226 1508935..1509417 1 NC_012441.1 MaoC domain-containing protein dehydratase 1509417 7677226 BMEA_A1594 Brucella melitensis ATCC 23457 MaoC domain-containing protein dehydratase YP_002733251.1 1508935 D 546272 CDS YP_002733252.1 225853019 7677227 complement(1509459..1510019) 1 NC_012441.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1510019 apt 7677227 apt Brucella melitensis ATCC 23457 adenine phosphoribosyltransferase YP_002733252.1 1509459 R 546272 CDS YP_002733253.1 225853020 7677228 1510064..1510180 1 NC_012441.1 hypothetical protein 1510180 7677228 BMEA_A1596 Brucella melitensis ATCC 23457 hypothetical protein YP_002733253.1 1510064 D 546272 CDS YP_002733254.1 225853021 7677229 complement(1510327..1511214) 1 NC_012441.1 cytochrome c1 1511214 7677229 BMEA_A1597 Brucella melitensis ATCC 23457 cytochrome c1 YP_002733254.1 1510327 R 546272 CDS YP_002733255.1 225853022 7677230 complement(1511228..1512526) 1 NC_012441.1 cytochrome b 1512526 7677230 BMEA_A1598 Brucella melitensis ATCC 23457 cytochrome b YP_002733255.1 1511228 R 546272 CDS YP_002733256.1 225853023 7677231 complement(1512548..1513111) 1 NC_012441.1 ubiquinol-cytochrome c reductase iron-sulfur subunit 1513111 petA 7677231 petA Brucella melitensis ATCC 23457 ubiquinol-cytochrome c reductase iron-sulfur subunit YP_002733256.1 1512548 R 546272 CDS YP_002733257.1 225853024 7677232 complement(1513363..1515231) 1 NC_012441.1 ABC transporter 1515231 7677232 BMEA_A1600 Brucella melitensis ATCC 23457 ABC transporter YP_002733257.1 1513363 R 546272 CDS YP_002733258.1 225853025 7677233 complement(1515385..1517277) 1 NC_012441.1 ABC transporter 1517277 7677233 BMEA_A1601 Brucella melitensis ATCC 23457 ABC transporter YP_002733258.1 1515385 R 546272 CDS YP_002733259.1 225853026 7677234 1517398..1517877 1 NC_012441.1 tRNA/rRNA methyltransferase SpoU 1517877 7677234 BMEA_A1602 Brucella melitensis ATCC 23457 tRNA/rRNA methyltransferase SpoU YP_002733259.1 1517398 D 546272 CDS YP_002733260.1 225853027 7677235 1517912..1519024 1 NC_012441.1 purine nucleoside permease 1519024 7677235 BMEA_A1603 Brucella melitensis ATCC 23457 purine nucleoside permease YP_002733260.1 1517912 D 546272 CDS YP_002733261.1 225853028 7677236 complement(1519136..1519396) 1 NC_012441.1 hypothetical protein 1519396 7677236 BMEA_A1604 Brucella melitensis ATCC 23457 hypothetical protein YP_002733261.1 1519136 R 546272 CDS YP_002733262.1 225853029 7677237 1519690..1520601 1 NC_012441.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1520601 7677237 BMEA_A1605 Brucella melitensis ATCC 23457 coproporphyrinogen III oxidase YP_002733262.1 1519690 D 546272 CDS YP_002733263.1 225853030 7677238 complement(1520635..1521129) 1 NC_012441.1 N-acetyltransferase GCN5 1521129 7677238 BMEA_A1606 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733263.1 1520635 R 546272 CDS YP_002733264.1 225853031 7677240 complement(1522162..1523433) 1 NC_012441.1 CCA-adding protein 1523433 7677240 BMEA_A1608 Brucella melitensis ATCC 23457 CCA-adding protein YP_002733264.1 1522162 R 546272 CDS YP_002733265.1 225853032 7677241 complement(1523430..1524053) 1 NC_012441.1 NUDIX hydrolase 1524053 7677241 BMEA_A1609 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002733265.1 1523430 R 546272 CDS YP_002733266.1 225853033 7677242 complement(1524050..1524715) 1 NC_012441.1 hypothetical protein 1524715 7677242 BMEA_A1610 Brucella melitensis ATCC 23457 hypothetical protein YP_002733266.1 1524050 R 546272 CDS YP_002733267.1 225853034 7677243 1524835..1525842 1 NC_012441.1 hypothetical protein 1525842 7677243 BMEA_A1611 Brucella melitensis ATCC 23457 hypothetical protein YP_002733267.1 1524835 D 546272 CDS YP_002733268.1 225853035 7677244 1525842..1526774 1 NC_012441.1 hypothetical protein 1526774 7677244 BMEA_A1612 Brucella melitensis ATCC 23457 hypothetical protein YP_002733268.1 1525842 D 546272 CDS YP_002733269.1 225853036 7677245 1526771..1529620 1 NC_012441.1 hypothetical protein 1529620 7677245 BMEA_A1613 Brucella melitensis ATCC 23457 hypothetical protein YP_002733269.1 1526771 D 546272 CDS YP_002733270.1 225853037 7677246 1529684..1531753 1 NC_012441.1 hypothetical protein 1531753 7677246 BMEA_A1614 Brucella melitensis ATCC 23457 hypothetical protein YP_002733270.1 1529684 D 546272 CDS YP_002733271.1 225853038 7677247 complement(1531821..1532327) 1 NC_012441.1 N-acetyltransferase GCN5 1532327 7677247 BMEA_A1615 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733271.1 1531821 R 546272 CDS YP_002733272.1 225853039 7677248 1532631..1533614 1 NC_012441.1 glutathione S-transferase 1533614 7677248 BMEA_A1616 Brucella melitensis ATCC 23457 glutathione S-transferase YP_002733272.1 1532631 D 546272 CDS YP_002733273.1 225853040 7677249 1533762..1534445 1 NC_012441.1 outer membrane protein alkL precursor 1534445 7677249 BMEA_A1617 Brucella melitensis ATCC 23457 outer membrane protein alkL precursor YP_002733273.1 1533762 D 546272 CDS YP_002733274.1 225853041 7677250 complement(1534479..1534934) 1 NC_012441.1 NUDIX hydrolase 1534934 7677250 BMEA_A1618 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002733274.1 1534479 R 546272 CDS YP_002733275.1 225853042 7676366 1535043..1535945 1 NC_012441.1 metallophosphoesterase 1535945 7676366 BMEA_A1619 Brucella melitensis ATCC 23457 metallophosphoesterase YP_002733275.1 1535043 D 546272 CDS YP_002733276.1 225853043 7676367 complement(1536146..1537873) 1 NC_012441.1 2-isopropylmalate synthase 1537873 leuA 7676367 leuA Brucella melitensis ATCC 23457 2-isopropylmalate synthase YP_002733276.1 1536146 R 546272 CDS YP_002733277.1 225853044 7676368 complement(1538005..1538163) 1 NC_012441.1 hypothetical protein 1538163 7676368 BMEA_A1621 Brucella melitensis ATCC 23457 hypothetical protein YP_002733277.1 1538005 R 546272 CDS YP_002733278.1 225853045 7676369 complement(1538178..1539086) 1 NC_012441.1 cation diffusion facilitator family transporter 1539086 7676369 BMEA_A1622 Brucella melitensis ATCC 23457 cation diffusion facilitator family transporter YP_002733278.1 1538178 R 546272 CDS YP_002733279.1 225853046 7676370 1539096..1539377 1 NC_012441.1 hypothetical protein 1539377 7676370 BMEA_A1623 Brucella melitensis ATCC 23457 hypothetical protein YP_002733279.1 1539096 D 546272 CDS YP_002733280.1 225853047 7676371 complement(1539555..1541750) 1 NC_012441.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase 1541750 7676371 BMEA_A1624 Brucella melitensis ATCC 23457 anthranilate synthase YP_002733280.1 1539555 R 546272 CDS YP_002733281.1 225853048 7676372 1542429..1542890 1 NC_012441.1 leucine-responsive regulatory protein 1542890 7676372 BMEA_A1626 Brucella melitensis ATCC 23457 leucine-responsive regulatory protein YP_002733281.1 1542429 D 546272 CDS YP_002733282.1 225853049 7676373 1543031..1543441 1 NC_012441.1 MarR family transcriptional regulator 1543441 7676373 BMEA_A1627 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002733282.1 1543031 D 546272 CDS YP_002733283.1 225853050 7676374 1543536..1544828 1 NC_012441.1 major facilitator superfamily protein 1544828 7676374 BMEA_A1628 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002733283.1 1543536 D 546272 CDS YP_002733284.1 225853051 7676375 complement(1544823..1545788) 1 NC_012441.1 hypothetical protein 1545788 7676375 BMEA_A1629 Brucella melitensis ATCC 23457 hypothetical protein YP_002733284.1 1544823 R 546272 CDS YP_002733285.1 225853052 7676376 complement(1545794..1546990) 1 NC_012441.1 hypothetical protein 1546990 7676376 BMEA_A1630 Brucella melitensis ATCC 23457 hypothetical protein YP_002733285.1 1545794 R 546272 CDS YP_002733286.1 225853053 7676377 complement(1546987..1547223) 1 NC_012441.1 hypothetical protein 1547223 7676377 BMEA_A1631 Brucella melitensis ATCC 23457 hypothetical protein YP_002733286.1 1546987 R 546272 CDS YP_002733287.1 225853054 7676378 1547426..1548394 1 NC_012441.1 choline ABC transporter periplasmic binding protein 1548394 choX 7676378 choX Brucella melitensis ATCC 23457 choline ABC transporter periplasmic binding protein YP_002733287.1 1547426 D 546272 CDS YP_002733288.1 225853055 7676379 1548483..1549319 1 NC_012441.1 choline ABC transporter permease 1549319 choW 7676379 choW Brucella melitensis ATCC 23457 choline ABC transporter permease YP_002733288.1 1548483 D 546272 CDS YP_002733289.1 225853056 7676380 1549489..1550535 1 NC_012441.1 choline ABC transporter ATP-binding protein 1550535 choV 7676380 choV Brucella melitensis ATCC 23457 choline ABC transporter ATP-binding protein YP_002733289.1 1549489 D 546272 CDS YP_002733290.1 225853057 7676381 complement(1550809..1551657) 1 NC_012441.1 hypothetical protein 1551657 7676381 BMEA_A1635 Brucella melitensis ATCC 23457 hypothetical protein YP_002733290.1 1550809 R 546272 CDS YP_002733291.1 225853058 7676382 complement(1551654..1552502) 1 NC_012441.1 ABC transporter 1552502 7676382 BMEA_A1636 Brucella melitensis ATCC 23457 ABC transporter YP_002733291.1 1551654 R 546272 CDS YP_002733292.1 225853059 7676383 complement(1552508..1553416) 1 NC_012441.1 dipeptide transport system permease DppC 1553416 7676383 BMEA_A1637 Brucella melitensis ATCC 23457 dipeptide transport system permease DppC YP_002733292.1 1552508 R 546272 CDS YP_002733293.1 225853060 7676384 complement(1553424..1554431) 1 NC_012441.1 dipeptide transport system permease DppB 1554431 7676384 BMEA_A1638 Brucella melitensis ATCC 23457 dipeptide transport system permease DppB YP_002733293.1 1553424 R 546272 CDS YP_002733294.1 225853061 7676386 1556596..1556772 1 NC_012441.1 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 1556772 7676386 BMEA_A1640 Brucella melitensis ATCC 23457 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_002733294.1 1556596 D 546272 CDS YP_002733295.1 225853062 7676387 complement(1557013..1557240) 1 NC_012441.1 hypothetical protein 1557240 7676387 BMEA_A1641 Brucella melitensis ATCC 23457 hypothetical protein YP_002733295.1 1557013 R 546272 CDS YP_002733296.1 225853063 7676388 1557230..1557577 1 NC_012441.1 nodulation protein nolR 1557577 7676388 BMEA_A1642 Brucella melitensis ATCC 23457 nodulation protein nolR YP_002733296.1 1557230 D 546272 CDS YP_002733297.1 225853064 7676389 1557607..1558437 1 NC_012441.1 tRNA/rRNA methyltransferase SpoU 1558437 7676389 BMEA_A1643 Brucella melitensis ATCC 23457 tRNA/rRNA methyltransferase SpoU YP_002733297.1 1557607 D 546272 CDS YP_002733298.1 225853065 7676390 complement(1558659..1559855) 1 NC_012441.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1559855 trmU 7676390 trmU Brucella melitensis ATCC 23457 tRNA-specific 2-thiouridylase MnmA YP_002733298.1 1558659 R 546272 CDS YP_002733299.1 225853066 7676391 complement(1559893..1560051) 1 NC_012441.1 hypothetical protein 1560051 7676391 BMEA_A1645 Brucella melitensis ATCC 23457 hypothetical protein YP_002733299.1 1559893 R 546272 CDS YP_002733300.1 225853067 7676392 1560160..1560435 1 NC_012441.1 hypothetical protein 1560435 7676392 BMEA_A1646 Brucella melitensis ATCC 23457 hypothetical protein YP_002733300.1 1560160 D 546272 CDS YP_002733301.1 225853068 7676393 complement(1560978..1561913) 1 NC_012441.1 myosin-14 1561913 7676393 BMEA_A1647 Brucella melitensis ATCC 23457 myosin-14 YP_002733301.1 1560978 R 546272 CDS YP_002733302.1 225853069 7676394 complement(1562143..1562739) 1 NC_012441.1 hypothetical protein 1562739 7676394 BMEA_A1648 Brucella melitensis ATCC 23457 hypothetical protein YP_002733302.1 1562143 R 546272 CDS YP_002733303.1 225853070 7676395 complement(1563009..1563152) 1 NC_012441.1 hypothetical protein 1563152 7676395 BMEA_A1649 Brucella melitensis ATCC 23457 hypothetical protein YP_002733303.1 1563009 R 546272 CDS YP_002733304.1 225853071 7676396 1563151..1563780 1 NC_012441.1 hypothetical protein 1563780 7676396 BMEA_A1650 Brucella melitensis ATCC 23457 hypothetical protein YP_002733304.1 1563151 D 546272 CDS YP_002733305.1 225853072 7676397 complement(1563893..1564591) 1 NC_012441.1 hypothetical protein 1564591 7676397 BMEA_A1651 Brucella melitensis ATCC 23457 hypothetical protein YP_002733305.1 1563893 R 546272 CDS YP_002733306.1 225853073 7676398 1565123..1565515 1 NC_012441.1 hypothetical protein 1565515 7676398 BMEA_A1652 Brucella melitensis ATCC 23457 hypothetical protein YP_002733306.1 1565123 D 546272 CDS YP_002733307.1 225853074 7676399 complement(1565599..1566723) 1 NC_012441.1 pleiotropic regulatory protein 1566723 7676399 BMEA_A1653 Brucella melitensis ATCC 23457 pleiotropic regulatory protein YP_002733307.1 1565599 R 546272 CDS YP_002733308.1 225853075 7676400 complement(1566883..1567839) 1 NC_012441.1 oxidoreductase domain-containing protein 1567839 7676400 BMEA_A1654 Brucella melitensis ATCC 23457 oxidoreductase domain-containing protein YP_002733308.1 1566883 R 546272 CDS YP_002733309.1 225853076 7676402 1568241..1568495 1 NC_012441.1 hypothetical protein 1568495 7676402 BMEA_A1656 Brucella melitensis ATCC 23457 hypothetical protein YP_002733309.1 1568241 D 546272 CDS YP_002733310.1 225853077 7676403 complement(1568671..1569453) 1 NC_012441.1 lacto-N-neotetraose biosynthesis glycosyl transferase 1569453 7676403 BMEA_A1657 Brucella melitensis ATCC 23457 lacto-N-neotetraose biosynthesis glycosyl transferase YP_002733310.1 1568671 R 546272 CDS YP_002733311.1 225853078 7676405 1570198..1573305 1 NC_012441.1 PAS domain S-box-containing protein 1573305 7676405 BMEA_A1659 Brucella melitensis ATCC 23457 PAS domain S-box-containing protein YP_002733311.1 1570198 D 546272 CDS YP_002733312.1 225853079 7676406 complement(1573525..1573656) 1 NC_012441.1 hypothetical protein 1573656 7676406 BMEA_A1660 Brucella melitensis ATCC 23457 hypothetical protein YP_002733312.1 1573525 R 546272 CDS YP_002733313.1 225853080 7676407 1574046..1575983 1 NC_012441.1 AsmA family protein 1575983 7676407 BMEA_A1661 Brucella melitensis ATCC 23457 AsmA family protein YP_002733313.1 1574046 D 546272 CDS YP_002733314.1 225853081 7676408 complement(1575991..1576812) 1 NC_012441.1 Spermidine/putrescine transport system permease potC 1576812 7676408 BMEA_A1662 Brucella melitensis ATCC 23457 Spermidine/putrescine transport system permease potC YP_002733314.1 1575991 R 546272 CDS YP_002733315.1 225853082 7676409 complement(1576814..1577725) 1 NC_012441.1 binding-protein-dependent transport systems inner membrane protein 1577725 7676409 BMEA_A1663 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane protein YP_002733315.1 1576814 R 546272 CDS YP_002733316.1 225853083 7676410 complement(1577741..1578886) 1 NC_012441.1 polyamine ABC transporter ATP-binding protein 1578886 7676410 BMEA_A1664 Brucella melitensis ATCC 23457 polyamine ABC transporter ATP-binding protein YP_002733316.1 1577741 R 546272 CDS YP_002733317.1 225853084 7676411 complement(1579128..1580231) 1 NC_012441.1 hypothetical protein 1580231 7676411 BMEA_A1665 Brucella melitensis ATCC 23457 hypothetical protein YP_002733317.1 1579128 R 546272 CDS YP_002733318.1 225853085 7676413 1582114..1583403 1 NC_012441.1 isocitrate lyase 1583403 aceA 7676413 aceA Brucella melitensis ATCC 23457 isocitrate lyase YP_002733318.1 1582114 D 546272 CDS YP_002733319.1 225853086 7676414 1583438..1583674 1 NC_012441.1 hypothetical protein 1583674 7676414 BMEA_A1668 Brucella melitensis ATCC 23457 hypothetical protein YP_002733319.1 1583438 D 546272 CDS YP_002733320.1 225853087 7676416 1584387..1585154 1 NC_012441.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1585154 7676416 BMEA_A1670 Brucella melitensis ATCC 23457 7-alpha-hydroxysteroid dehydrogenase YP_002733320.1 1584387 D 546272 CDS YP_002733321.1 225853088 7676417 1585220..1586014 1 NC_012441.1 hypothetical protein 1586014 7676417 BMEA_A1671 Brucella melitensis ATCC 23457 hypothetical protein YP_002733321.1 1585220 D 546272 CDS YP_002733322.1 225853089 7676418 1586021..1587781 1 NC_012441.1 hypothetical protein 1587781 7676418 BMEA_A1672 Brucella melitensis ATCC 23457 hypothetical protein YP_002733322.1 1586021 D 546272 CDS YP_002733323.1 225853090 7676419 1587797..1588411 1 NC_012441.1 hypothetical protein 1588411 7676419 BMEA_A1673 Brucella melitensis ATCC 23457 hypothetical protein YP_002733323.1 1587797 D 546272 CDS YP_002733324.1 225853091 7676420 1588635..1589243 1 NC_012441.1 outer membrane protein Omp31 1589243 7676420 BMEA_A1674 Brucella melitensis ATCC 23457 outer membrane protein Omp31 YP_002733324.1 1588635 D 546272 CDS YP_002733325.1 225853092 7676421 complement(1589380..1590930) 1 NC_012441.1 patatin 1590930 7676421 BMEA_A1675 Brucella melitensis ATCC 23457 patatin YP_002733325.1 1589380 R 546272 CDS YP_002733326.1 225853093 7676422 1591483..1591764 1 NC_012441.1 hypothetical protein 1591764 7676422 BMEA_A1676 Brucella melitensis ATCC 23457 hypothetical protein YP_002733326.1 1591483 D 546272 CDS YP_002733327.1 225853094 7676423 complement(1592041..1592784) 1 NC_012441.1 dihydroxyacetone kinase subunit L 1592784 7676423 BMEA_A1677 Brucella melitensis ATCC 23457 dihydroxyacetone kinase subunit L YP_002733327.1 1592041 R 546272 CDS YP_002733328.1 225853095 7676424 complement(1592754..1594838) 1 NC_012441.1 glycerone kinase 1594838 7676424 BMEA_A1678 Brucella melitensis ATCC 23457 glycerone kinase YP_002733328.1 1592754 R 546272 CDS YP_002733329.1 225853096 7676425 complement(1594997..1595653) 1 NC_012441.1 dihydroxyacetone kinase subunit L 1595653 7676425 BMEA_A1679 Brucella melitensis ATCC 23457 dihydroxyacetone kinase subunit L YP_002733329.1 1594997 R 546272 CDS YP_002733330.1 225853097 7676426 complement(1595650..1596678) 1 NC_012441.1 glycerone kinase 1596678 7676426 BMEA_A1680 Brucella melitensis ATCC 23457 glycerone kinase YP_002733330.1 1595650 R 546272 CDS YP_002733331.1 225853098 7676428 complement(1597541..1598530) 1 NC_012441.1 rhizopine-binding protein 1598530 7676428 BMEA_A1682 Brucella melitensis ATCC 23457 rhizopine-binding protein YP_002733331.1 1597541 R 546272 CDS YP_002733332.1 225853099 7676429 complement(1598706..1599710) 1 NC_012441.1 hypothetical protein 1599710 7676429 BMEA_A1683 Brucella melitensis ATCC 23457 hypothetical protein YP_002733332.1 1598706 R 546272 CDS YP_002733333.1 225853100 7676430 complement(1599806..1601227) 1 NC_012441.1 ribose/galactose/methyl galactoside import ATP-binding protein 2 1601227 7676430 BMEA_A1684 Brucella melitensis ATCC 23457 ribose/galactose/methyl galactoside import ATP-binding protein 2 YP_002733333.1 1599806 R 546272 CDS YP_002733334.1 225853101 7676431 1601579..1601896 1 NC_012441.1 hypothetical protein 1601896 7676431 BMEA_A1685 Brucella melitensis ATCC 23457 hypothetical protein YP_002733334.1 1601579 D 546272 CDS YP_002733335.1 225853102 7676432 complement(1602026..1602154) 1 NC_012441.1 hypothetical protein 1602154 7676432 BMEA_A1686 Brucella melitensis ATCC 23457 hypothetical protein YP_002733335.1 1602026 R 546272 CDS YP_002733336.1 225853103 7676596 1602253..1603914 1 NC_012441.1 choline dehydrogenase 1603914 7676596 BMEA_A1687 Brucella melitensis ATCC 23457 choline dehydrogenase YP_002733336.1 1602253 D 546272 CDS YP_002733337.1 225853104 7676599 1604563..1604715 1 NC_012441.1 hypothetical protein 1604715 7676599 BMEA_A1690 Brucella melitensis ATCC 23457 hypothetical protein YP_002733337.1 1604563 D 546272 CDS YP_002733338.1 225853105 7676601 1607670..1607912 1 NC_012441.1 hypothetical protein 1607912 7676601 BMEA_A1692 Brucella melitensis ATCC 23457 hypothetical protein YP_002733338.1 1607670 D 546272 CDS YP_002733339.1 225853106 7676605 complement(1610613..1611434) 1 NC_012441.1 regulatory protein IclR 1611434 7676605 BMEA_A1696 Brucella melitensis ATCC 23457 regulatory protein IclR YP_002733339.1 1610613 R 546272 CDS YP_002733340.1 225853107 7676606 1611552..1613003 1 NC_012441.1 succinate-semialdehyde dehydrogenase 1613003 7676606 BMEA_A1697 Brucella melitensis ATCC 23457 succinate-semialdehyde dehydrogenase YP_002733340.1 1611552 D 546272 CDS YP_002733341.1 225853108 7676607 1613120..1613710 1 NC_012441.1 hypothetical protein 1613710 7676607 BMEA_A1698 Brucella melitensis ATCC 23457 hypothetical protein YP_002733341.1 1613120 D 546272 CDS YP_002733342.1 225853109 7676608 1613823..1614341 1 NC_012441.1 disulfide bond formation protein B 1614341 7676608 BMEA_A1699 Brucella melitensis ATCC 23457 disulfide bond formation protein B YP_002733342.1 1613823 D 546272 CDS YP_002733343.1 225853110 7676609 complement(1614358..1614930) 1 NC_012441.1 HNH endonuclease 1614930 7676609 BMEA_A1700 Brucella melitensis ATCC 23457 HNH endonuclease YP_002733343.1 1614358 R 546272 CDS YP_002733344.1 225853111 7676610 complement(1615204..1615902) 1 NC_012441.1 HhH-GPD family protein 1615902 7676610 BMEA_A1701 Brucella melitensis ATCC 23457 HhH-GPD family protein YP_002733344.1 1615204 R 546272 CDS YP_002733345.1 225853112 7676611 1615924..1616799 1 NC_012441.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1616799 7676611 BMEA_A1702 Brucella melitensis ATCC 23457 glutamyl-Q tRNA(Asp) synthetase YP_002733345.1 1615924 D 546272 CDS YP_002733346.1 225853113 7676612 1616942..1619128 1 NC_012441.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 1619128 glcB 7676612 glcB Brucella melitensis ATCC 23457 malate synthase G YP_002733346.1 1616942 D 546272 CDS YP_002733347.1 225853114 7676613 1619203..1619304 1 NC_012441.1 hypothetical protein 1619304 7676613 BMEA_A1704 Brucella melitensis ATCC 23457 hypothetical protein YP_002733347.1 1619203 D 546272 CDS YP_002733348.1 225853115 7676614 1619433..1619927 1 NC_012441.1 N-acetyltransferase GCN5 1619927 7676614 BMEA_A1705 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733348.1 1619433 D 546272 CDS YP_002733349.1 225853116 7676615 complement(1619986..1620897) 1 NC_012441.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1620897 rpoH 7676615 rpoH Brucella melitensis ATCC 23457 RNA polymerase factor sigma-32 YP_002733349.1 1619986 R 546272 CDS YP_002733350.1 225853117 7676616 complement(1621328..1622371) 1 NC_012441.1 pseudouridine synthase 1622371 7676616 BMEA_A1707 Brucella melitensis ATCC 23457 pseudouridine synthase YP_002733350.1 1621328 R 546272 CDS YP_002733351.1 225853118 7676617 1622388..1622864 1 NC_012441.1 hypothetical protein 1622864 7676617 BMEA_A1708 Brucella melitensis ATCC 23457 hypothetical protein YP_002733351.1 1622388 D 546272 CDS YP_002733352.1 225853119 7676618 1622898..1623071 1 NC_012441.1 hypothetical protein 1623071 7676618 BMEA_A1709 Brucella melitensis ATCC 23457 hypothetical protein YP_002733352.1 1622898 D 546272 CDS YP_002733353.1 225853120 7676620 1623243..1623668 1 NC_012441.1 ferric uptake regulation protein 1623668 7676620 BMEA_A1711 Brucella melitensis ATCC 23457 ferric uptake regulation protein YP_002733353.1 1623243 D 546272 CDS YP_002733354.1 225853121 7676621 complement(1623904..1624839) 1 NC_012441.1 signal transduction histidine kinase 1624839 7676621 BMEA_A1712 Brucella melitensis ATCC 23457 signal transduction histidine kinase YP_002733354.1 1623904 R 546272 CDS YP_002733355.1 225853122 7676622 complement(1625107..1625316) 1 NC_012441.1 hypothetical protein 1625316 7676622 BMEA_A1713 Brucella melitensis ATCC 23457 hypothetical protein YP_002733355.1 1625107 R 546272 CDS YP_002733356.1 225853123 7676623 complement(1625421..1626215) 1 NC_012441.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 1626215 7676623 BMEA_A1714 Brucella melitensis ATCC 23457 two-component response regulator YP_002733356.1 1625421 R 546272 CDS YP_002733357.1 225853124 7676624 1626661..1627233 1 NC_012441.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1627233 7676624 BMEA_A1715 Brucella melitensis ATCC 23457 RNA polymerase sigma factor YP_002733357.1 1626661 D 546272 CDS YP_002733358.1 225853125 7676625 1627433..1628875 1 NC_012441.1 signal transduction histidine kinase 1628875 7676625 BMEA_A1716 Brucella melitensis ATCC 23457 signal transduction histidine kinase YP_002733358.1 1627433 D 546272 CDS YP_002733359.1 225853126 7676626 complement(1628936..1629367) 1 NC_012441.1 hypothetical protein 1629367 7676626 BMEA_A1717 Brucella melitensis ATCC 23457 hypothetical protein YP_002733359.1 1628936 R 546272 CDS YP_002733360.1 225853127 7676627 complement(1629376..1629729) 1 NC_012441.1 hypothetical protein 1629729 7676627 BMEA_A1718 Brucella melitensis ATCC 23457 hypothetical protein YP_002733360.1 1629376 R 546272 CDS YP_002733361.1 225853128 7676629 complement(1630908..1631066) 1 NC_012441.1 hypothetical protein 1631066 7676629 BMEA_A1720 Brucella melitensis ATCC 23457 hypothetical protein YP_002733361.1 1630908 R 546272 CDS YP_002733362.1 225853129 7676630 1631197..1631400 1 NC_012441.1 hypothetical protein 1631400 7676630 BMEA_A1721 Brucella melitensis ATCC 23457 hypothetical protein YP_002733362.1 1631197 D 546272 CDS YP_002733363.1 225853130 7676631 1631517..1632440 1 NC_012441.1 TonB-system energizer ExbB 1632440 exbB 7676631 exbB Brucella melitensis ATCC 23457 TonB-system energizer ExbB YP_002733363.1 1631517 D 546272 CDS YP_002733364.1 225853131 7676632 1632446..1632970 1 NC_012441.1 TonB system transport protein ExbD 1632970 exbD 7676632 exbD Brucella melitensis ATCC 23457 TonB system transport protein ExbD YP_002733364.1 1632446 D 546272 CDS YP_002733365.1 225853132 7676633 1632937..1633788 1 NC_012441.1 TonB family C-terminal domain-containing protein 1633788 7676633 BMEA_A1724 Brucella melitensis ATCC 23457 TonB family C-terminal domain-containing protein YP_002733365.1 1632937 D 546272 CDS YP_002733366.1 225853133 7676634 complement(1633831..1634601) 1 NC_012441.1 hypothetical protein 1634601 7676634 BMEA_A1725 Brucella melitensis ATCC 23457 hypothetical protein YP_002733366.1 1633831 R 546272 CDS YP_002733367.1 225853134 7676636 complement(1636574..1637800) 1 NC_012441.1 RND family efflux transporter 1637800 7676636 BMEA_A1727 Brucella melitensis ATCC 23457 RND family efflux transporter YP_002733367.1 1636574 R 546272 CDS YP_002733368.1 225853135 7676637 complement(1638035..1638508) 1 NC_012441.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1638508 dut 7676637 dut Brucella melitensis ATCC 23457 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002733368.1 1638035 R 546272 CDS YP_002733369.1 225853136 7676638 complement(1638730..1639200) 1 NC_012441.1 AsnC family transcriptional regulator 1639200 7676638 BMEA_A1729 Brucella melitensis ATCC 23457 AsnC family transcriptional regulator YP_002733369.1 1638730 R 546272 CDS YP_002733370.1 225853137 7676639 1639346..1639561 1 NC_012441.1 hypothetical protein 1639561 7676639 BMEA_A1730 Brucella melitensis ATCC 23457 hypothetical protein YP_002733370.1 1639346 D 546272 CDS YP_002733371.1 225853138 7676643 1641670..1643022 1 NC_012441.1 hypothetical protein 1643022 7676643 BMEA_A1734 Brucella melitensis ATCC 23457 hypothetical protein YP_002733371.1 1641670 D 546272 CDS YP_002733372.1 225853139 7676644 complement(1643131..1644528) 1 NC_012441.1 hypothetical protein 1644528 7676644 BMEA_A1735 Brucella melitensis ATCC 23457 hypothetical protein YP_002733372.1 1643131 R 546272 CDS YP_002733373.1 225853140 7676645 complement(1644841..1646130) 1 NC_012441.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1646130 purA 7676645 purA Brucella melitensis ATCC 23457 adenylosuccinate synthetase YP_002733373.1 1644841 R 546272 CDS YP_002733374.1 225853141 7676646 complement(1646448..1646957) 1 NC_012441.1 N-acetyltransferase GCN5 1646957 7676646 BMEA_A1737 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733374.1 1646448 R 546272 CDS YP_002733375.1 225853142 7676647 complement(1646962..1648563) 1 NC_012441.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1648563 serA 7676647 serA Brucella melitensis ATCC 23457 D-3-phosphoglycerate dehydrogenase YP_002733375.1 1646962 R 546272 CDS YP_002733376.1 225853143 7676648 complement(1648706..1649881) 1 NC_012441.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 1649881 7676648 BMEA_A1739 Brucella melitensis ATCC 23457 phosphoserine aminotransferase YP_002733376.1 1648706 R 546272 CDS YP_002733377.1 225853144 7676649 complement(1650032..1650988) 1 NC_012441.1 bile acid:sodium symporter 1650988 7676649 BMEA_A1741 Brucella melitensis ATCC 23457 bile acid:sodium symporter YP_002733377.1 1650032 R 546272 CDS YP_002733378.1 225853145 7676650 complement(1651169..1651993) 1 NC_012441.1 opacity type porin 1651993 7676650 BMEA_A1742 Brucella melitensis ATCC 23457 opacity type porin YP_002733378.1 1651169 R 546272 CDS YP_002733379.1 225853146 7676651 complement(1652178..1653557) 1 NC_012441.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1653557 glmM 7676651 glmM Brucella melitensis ATCC 23457 phosphoglucosamine mutase YP_002733379.1 1652178 R 546272 CDS YP_002733380.1 225853147 7676652 complement(1653838..1655772) 1 NC_012441.1 ATP-dependent metalloprotease FtsH 1655772 ftsH 7676652 ftsH Brucella melitensis ATCC 23457 ATP-dependent metalloprotease FtsH YP_002733380.1 1653838 R 546272 CDS YP_002733381.1 225853148 7676653 complement(1655908..1657254) 1 NC_012441.1 tRNA(Ile)-lysidine synthetase 1657254 tilS 7676653 tilS Brucella melitensis ATCC 23457 tRNA(Ile)-lysidine synthetase YP_002733381.1 1655908 R 546272 CDS YP_002733382.1 225853149 7676654 complement(1657270..1658736) 1 NC_012441.1 Tol-Pal system protein YbgF 1658736 ygbF 7676654 ygbF Brucella melitensis ATCC 23457 Tol-Pal system protein YbgF YP_002733382.1 1657270 R 546272 CDS YP_002733383.1 225853150 7676655 complement(1659133..1659639) 1 NC_012441.1 peptidoglycan-associated lipoprotein 1659639 pal 7676655 pal Brucella melitensis ATCC 23457 peptidoglycan-associated lipoprotein YP_002733383.1 1659133 R 546272 CDS YP_002733384.1 225853151 7676656 complement(1659688..1659867) 1 NC_012441.1 hypothetical protein 1659867 7676656 BMEA_A1748 Brucella melitensis ATCC 23457 hypothetical protein YP_002733384.1 1659688 R 546272 CDS YP_002733385.1 225853152 7676657 complement(1659927..1661258) 1 NC_012441.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1661258 tolB 7676657 tolB Brucella melitensis ATCC 23457 translocation protein TolB YP_002733385.1 1659927 R 546272 CDS YP_002733386.1 225853153 7676658 complement(1661314..1662384) 1 NC_012441.1 hypothetical protein 1662384 7676658 BMEA_A1750 Brucella melitensis ATCC 23457 hypothetical protein YP_002733386.1 1661314 R 546272 CDS YP_002733387.1 225853154 7676659 complement(1662392..1662844) 1 NC_012441.1 protein TolR 1662844 tolR 7676659 tolR Brucella melitensis ATCC 23457 protein TolR YP_002733387.1 1662392 R 546272 CDS YP_002733388.1 225853155 7676660 complement(1662891..1663601) 1 NC_012441.1 protein TolQ 1663601 tolQ 7676660 tolQ Brucella melitensis ATCC 23457 protein TolQ YP_002733388.1 1662891 R 546272 CDS YP_002733389.1 225853156 7676661 1663637..1663804 1 NC_012441.1 hypothetical protein 1663804 7676661 BMEA_A1753 Brucella melitensis ATCC 23457 hypothetical protein YP_002733389.1 1663637 D 546272 CDS YP_002733390.1 225853157 7676662 complement(1663976..1664257) 1 NC_012441.1 thioesterase superfamily protein 1664257 7676662 BMEA_A1754 Brucella melitensis ATCC 23457 thioesterase superfamily protein YP_002733390.1 1663976 R 546272 CDS YP_002733391.1 225853158 7677476 complement(1664422..1665462) 1 NC_012441.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1665462 ruvB 7677476 ruvB Brucella melitensis ATCC 23457 Holliday junction DNA helicase RuvB YP_002733391.1 1664422 R 546272 CDS YP_002733392.1 225853159 7676936 complement(1665503..1666120) 1 NC_012441.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1666120 ruvA 7676936 ruvA Brucella melitensis ATCC 23457 Holliday junction DNA helicase RuvA YP_002733392.1 1665503 R 546272 CDS YP_002733393.1 225853160 7676937 complement(1666125..1666646) 1 NC_012441.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1666646 ruvC 7676937 ruvC Brucella melitensis ATCC 23457 Holliday junction resolvase YP_002733393.1 1666125 R 546272 CDS YP_002733394.1 225853161 7676938 complement(1666748..1667254) 1 NC_012441.1 hypothetical protein 1667254 7676938 BMEA_A1758 Brucella melitensis ATCC 23457 hypothetical protein YP_002733394.1 1666748 R 546272 CDS YP_002733395.1 225853162 7676939 complement(1667742..1668923) 1 NC_012441.1 hypothetical protein 1668923 7676939 BMEA_A1759 Brucella melitensis ATCC 23457 hypothetical protein YP_002733395.1 1667742 R 546272 CDS YP_002733396.1 225853163 7676940 1669168..1669833 1 NC_012441.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1669833 7676940 BMEA_A1760 Brucella melitensis ATCC 23457 thiamine-phosphate pyrophosphorylase YP_002733396.1 1669168 D 546272 CDS YP_002733397.1 225853164 7676941 1669834..1670922 1 NC_012441.1 Sel1 domain-containing protein repeat-containing protein 1670922 7676941 BMEA_A1761 Brucella melitensis ATCC 23457 Sel1 domain-containing protein repeat-containing protein YP_002733397.1 1669834 D 546272 CDS YP_002733398.1 225853165 7676942 1671187..1671747 1 NC_012441.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1671747 efp 7676942 efp Brucella melitensis ATCC 23457 elongation factor P YP_002733398.1 1671187 D 546272 CDS YP_002733399.1 225853166 7676943 1671933..1672724 1 NC_012441.1 inositol-phosphate phosphatase 1672724 7676943 BMEA_A1763 Brucella melitensis ATCC 23457 inositol-phosphate phosphatase YP_002733399.1 1671933 D 546272 CDS YP_002733400.1 225853167 7676944 1672729..1672839 1 NC_012441.1 hypothetical protein 1672839 7676944 BMEA_A1764 Brucella melitensis ATCC 23457 hypothetical protein YP_002733400.1 1672729 D 546272 CDS YP_002733401.1 225853168 7676945 1672979..1674028 1 NC_012441.1 hypothetical protein 1674028 7676945 BMEA_A1765 Brucella melitensis ATCC 23457 hypothetical protein YP_002733401.1 1672979 D 546272 CDS YP_002733402.1 225853169 7676946 1674035..1675066 1 NC_012441.1 hypothetical protein 1675066 7676946 BMEA_A1766 Brucella melitensis ATCC 23457 hypothetical protein YP_002733402.1 1674035 D 546272 CDS YP_002733403.1 225853170 7676947 complement(1675100..1676899) 1 NC_012441.1 ABC transporter ATP-binding protein/permease 1676899 7676947 BMEA_A1767 Brucella melitensis ATCC 23457 ABC transporter ATP-binding protein/permease YP_002733403.1 1675100 R 546272 CDS YP_002733404.1 225853171 7676948 1677215..1677436 1 NC_012441.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1677436 rpmE 7676948 rpmE Brucella melitensis ATCC 23457 50S ribosomal protein L31 YP_002733404.1 1677215 D 546272 CDS YP_002733405.1 225853172 7676949 complement(1677664..1678410) 1 NC_012441.1 hypothetical protein 1678410 7676949 BMEA_A1769 Brucella melitensis ATCC 23457 hypothetical protein YP_002733405.1 1677664 R 546272 CDS YP_002733406.1 225853173 7676950 1678631..1679323 1 NC_012441.1 GntR family transcriptional regulator 1679323 7676950 BMEA_A1770 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733406.1 1678631 D 546272 CDS YP_002733407.1 225853174 7676951 1679485..1680060 1 NC_012441.1 BioY protein 1680060 7676951 BMEA_A1771 Brucella melitensis ATCC 23457 BioY protein YP_002733407.1 1679485 D 546272 CDS YP_002733408.1 225853175 7676952 1680071..1680499 1 NC_012441.1 hypothetical protein 1680499 7676952 BMEA_A1772 Brucella melitensis ATCC 23457 hypothetical protein YP_002733408.1 1680071 D 546272 CDS YP_002733409.1 225853176 7676953 complement(1680512..1681255) 1 NC_012441.1 integral membrane protein TerC 1681255 7676953 BMEA_A1773 Brucella melitensis ATCC 23457 integral membrane protein TerC YP_002733409.1 1680512 R 546272 CDS YP_002733410.1 225853177 7676954 complement(1681466..1682290) 1 NC_012441.1 hypothetical protein 1682290 7676954 BMEA_A1774 Brucella melitensis ATCC 23457 hypothetical protein YP_002733410.1 1681466 R 546272 CDS YP_002733411.1 225853178 7676955 complement(1682399..1682995) 1 NC_012441.1 5,10-methenyltetrahydrofolate synthetase 1682995 7676955 BMEA_A1775 Brucella melitensis ATCC 23457 5,10-methenyltetrahydrofolate synthetase YP_002733411.1 1682399 R 546272 CDS YP_002733412.1 225853179 7676957 complement(1683383..1683748) 1 NC_012441.1 hypothetical protein 1683748 7676957 BMEA_A1778 Brucella melitensis ATCC 23457 hypothetical protein YP_002733412.1 1683383 R 546272 CDS YP_002733413.1 225853180 7676958 complement(1683758..1684030) 1 NC_012441.1 hypothetical protein 1684030 7676958 BMEA_A1779 Brucella melitensis ATCC 23457 hypothetical protein YP_002733413.1 1683758 R 546272 CDS YP_002733414.1 225853181 7676959 1684447..1686438 1 NC_012441.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1686438 tkt 7676959 tkt Brucella melitensis ATCC 23457 transketolase YP_002733414.1 1684447 D 546272 CDS YP_002733415.1 225853182 7676960 1686579..1687586 1 NC_012441.1 glyceraldehyde-3-phosphate dehydrogenase 1687586 gap 7676960 gap Brucella melitensis ATCC 23457 glyceraldehyde-3-phosphate dehydrogenase YP_002733415.1 1686579 D 546272 CDS YP_002733416.1 225853183 7676961 1687654..1688844 1 NC_012441.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1688844 7676961 BMEA_A1782 Brucella melitensis ATCC 23457 phosphoglycerate kinase YP_002733416.1 1687654 D 546272 CDS YP_002733417.1 225853184 7676962 complement(1689135..1689299) 1 NC_012441.1 hypothetical protein 1689299 7676962 BMEA_A1783 Brucella melitensis ATCC 23457 hypothetical protein YP_002733417.1 1689135 R 546272 CDS YP_002733418.1 225853185 7676963 1689573..1691483 1 NC_012441.1 propionate--CoA ligase 1691483 7676963 BMEA_A1784 Brucella melitensis ATCC 23457 propionate--CoA ligase YP_002733418.1 1689573 D 546272 CDS YP_002733419.1 225853186 7676964 1691867..1692052 1 NC_012441.1 hypothetical protein 1692052 7676964 BMEA_A1786 Brucella melitensis ATCC 23457 hypothetical protein YP_002733419.1 1691867 D 546272 CDS YP_002733420.1 225853187 7676965 1692059..1692760 1 NC_012441.1 hypothetical protein 1692760 7676965 BMEA_A1787 Brucella melitensis ATCC 23457 hypothetical protein YP_002733420.1 1692059 D 546272 CDS YP_002733421.1 225853188 7676966 1693163..1693570 1 NC_012441.1 hypothetical protein 1693570 7676966 BMEA_A1788 Brucella melitensis ATCC 23457 hypothetical protein YP_002733421.1 1693163 D 546272 CDS YP_002733422.1 225853189 7676967 complement(1693648..1694337) 1 NC_012441.1 hypothetical protein 1694337 7676967 BMEA_A1789 Brucella melitensis ATCC 23457 hypothetical protein YP_002733422.1 1693648 R 546272 CDS YP_002733423.1 225853190 7676968 complement(1694465..1695469) 1 NC_012441.1 quinone oxidoreductase, PIG3 family protein 1695469 7676968 BMEA_A1790 Brucella melitensis ATCC 23457 quinone oxidoreductase, PIG3 family protein YP_002733423.1 1694465 R 546272 CDS YP_002733424.1 225853191 7676969 1695662..1695853 1 NC_012441.1 hypothetical protein 1695853 7676969 BMEA_A1791 Brucella melitensis ATCC 23457 hypothetical protein YP_002733424.1 1695662 D 546272 CDS YP_002733425.1 225853192 7676970 1695951..1697189 1 NC_012441.1 major facilitator superfamily protein 1697189 7676970 BMEA_A1792 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002733425.1 1695951 D 546272 CDS YP_002733426.1 225853193 7676971 complement(1697332..1697511) 1 NC_012441.1 hypothetical protein 1697511 7676971 BMEA_A1793 Brucella melitensis ATCC 23457 hypothetical protein YP_002733426.1 1697332 R 546272 CDS YP_002733427.1 225853194 7676972 complement(1697570..1697791) 1 NC_012441.1 hypothetical protein 1697791 7676972 BMEA_A1794 Brucella melitensis ATCC 23457 hypothetical protein YP_002733427.1 1697570 R 546272 CDS YP_002733428.1 225853195 7676973 1697905..1698108 1 NC_012441.1 hypothetical protein 1698108 7676973 BMEA_A1795 Brucella melitensis ATCC 23457 hypothetical protein YP_002733428.1 1697905 D 546272 CDS YP_002733429.1 225853196 7676974 1698206..1698694 1 NC_012441.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 1698694 purE 7676974 purE Brucella melitensis ATCC 23457 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_002733429.1 1698206 D 546272 CDS YP_002733430.1 225853197 7676975 1698711..1699799 1 NC_012441.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1699799 purK 7676975 purK Brucella melitensis ATCC 23457 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002733430.1 1698711 D 546272 CDS YP_002733431.1 225853198 7676976 1699966..1700160 1 NC_012441.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1700160 7676976 BMEA_A1798 Brucella melitensis ATCC 23457 50S ribosomal protein L36 YP_002733431.1 1699966 D 546272 CDS YP_002733432.1 225853199 7676977 1700198..1700887 1 NC_012441.1 hypothetical protein 1700887 7676977 BMEA_A1799 Brucella melitensis ATCC 23457 hypothetical protein YP_002733432.1 1700198 D 546272 CDS YP_002733433.1 225853200 7676978 complement(1701139..1702575) 1 NC_012441.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1702575 pyk 7676978 pyk Brucella melitensis ATCC 23457 pyruvate kinase YP_002733433.1 1701139 R 546272 CDS YP_002733434.1 225853201 7676979 complement(1702572..1703033) 1 NC_012441.1 hypothetical protein 1703033 7676979 BMEA_A1801 Brucella melitensis ATCC 23457 hypothetical protein YP_002733434.1 1702572 R 546272 CDS YP_002733435.1 225853202 7676980 1703274..1704092 1 NC_012441.1 N-formylglutamate amidohydrolase 1704092 7676980 BMEA_A1802 Brucella melitensis ATCC 23457 N-formylglutamate amidohydrolase YP_002733435.1 1703274 D 546272 CDS YP_002733436.1 225853203 7676981 1704089..1704250 1 NC_012441.1 hypothetical protein 1704250 7676981 BMEA_A1803 Brucella melitensis ATCC 23457 hypothetical protein YP_002733436.1 1704089 D 546272 CDS YP_002733437.1 225853204 7676982 1704265..1704525 1 NC_012441.1 hypothetical protein 1704525 7676982 BMEA_A1804 Brucella melitensis ATCC 23457 hypothetical protein YP_002733437.1 1704265 D 546272 CDS YP_002733438.1 225853205 7676983 complement(1704617..1706434) 1 NC_012441.1 ABC transporter 1706434 7676983 BMEA_A1805 Brucella melitensis ATCC 23457 ABC transporter YP_002733438.1 1704617 R 546272 CDS YP_002733439.1 225853206 7676984 complement(1706582..1706866) 1 NC_012441.1 hypothetical protein 1706866 7676984 BMEA_A1807 Brucella melitensis ATCC 23457 hypothetical protein YP_002733439.1 1706582 R 546272 CDS YP_002733440.1 225853207 7676985 complement(1707000..1707656) 1 NC_012441.1 thiamine pyrophosphokinase 1707656 7676985 BMEA_A1808 Brucella melitensis ATCC 23457 thiamine pyrophosphokinase YP_002733440.1 1707000 R 546272 CDS YP_002733441.1 225853208 7676986 1707963..1708967 1 NC_012441.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 1708967 thiB 7676986 thiB Brucella melitensis ATCC 23457 thiamine transporter substrate binding subunit YP_002733441.1 1707963 D 546272 CDS YP_002733442.1 225853209 7676987 1708943..1710595 1 NC_012441.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1710595 thiP 7676987 thiP Brucella melitensis ATCC 23457 thiamine transporter membrane protein YP_002733442.1 1708943 D 546272 CDS YP_002733443.1 225853210 7676988 1710592..1711317 1 NC_012441.1 thiamine ABC transporter ATP-binding protein 1711317 7676988 BMEA_A1812 Brucella melitensis ATCC 23457 thiamine ABC transporter ATP-binding protein YP_002733443.1 1710592 D 546272 CDS YP_002733444.1 225853211 7676989 1711584..1713065 1 NC_012441.1 peptidase M48 Ste24p 1713065 7676989 BMEA_A1813 Brucella melitensis ATCC 23457 peptidase M48 Ste24p YP_002733444.1 1711584 D 546272 CDS YP_002733445.1 225853212 7676990 1713092..1713820 1 NC_012441.1 MOSC domain-containing protein 1713820 7676990 BMEA_A1814 Brucella melitensis ATCC 23457 MOSC domain-containing protein YP_002733445.1 1713092 D 546272 CDS YP_002733446.1 225853213 7676991 complement(1713908..1714843) 1 NC_012441.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 1714843 7676991 BMEA_A1815 Brucella melitensis ATCC 23457 RNA polymerase factor sigma-32 YP_002733446.1 1713908 R 546272 CDS YP_002733447.1 225853214 7676992 1714884..1715087 1 NC_012441.1 hypothetical protein 1715087 7676992 BMEA_A1816 Brucella melitensis ATCC 23457 hypothetical protein YP_002733447.1 1714884 D 546272 CDS YP_002733448.1 225853215 7676993 complement(1715007..1715216) 1 NC_012441.1 hypothetical protein 1715216 7676993 BMEA_A1817 Brucella melitensis ATCC 23457 hypothetical protein YP_002733448.1 1715007 R 546272 CDS YP_002733449.1 225853216 7676994 complement(1715188..1715763) 1 NC_012441.1 hypothetical protein 1715763 7676994 BMEA_A1818 Brucella melitensis ATCC 23457 hypothetical protein YP_002733449.1 1715188 R 546272 CDS YP_002733450.1 225853217 7676995 complement(1716281..1716619) 1 NC_012441.1 ferredoxin-2 1716619 7676995 BMEA_A1819 Brucella melitensis ATCC 23457 ferredoxin-2 YP_002733450.1 1716281 R 546272 CDS YP_002733451.1 225853218 7676996 complement(1716983..1717384) 1 NC_012441.1 RNA-binding S4 domain-containing protein 1717384 7676996 BMEA_A1820 Brucella melitensis ATCC 23457 RNA-binding S4 domain-containing protein YP_002733451.1 1716983 R 546272 CDS YP_002733452.1 225853219 7676997 complement(1717420..1720506) 1 NC_012441.1 ATP-dependent helicase 1720506 7676997 BMEA_A1821 Brucella melitensis ATCC 23457 ATP-dependent helicase YP_002733452.1 1717420 R 546272 CDS YP_002733453.1 225853220 7676998 complement(1720599..1722113) 1 NC_012441.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 1722113 7676998 BMEA_A1822 Brucella melitensis ATCC 23457 acetyl-CoA acetyltransferase YP_002733453.1 1720599 R 546272 CDS YP_002733454.1 225853221 7676999 1722259..1722690 1 NC_012441.1 hypothetical protein 1722690 7676999 BMEA_A1824 Brucella melitensis ATCC 23457 hypothetical protein YP_002733454.1 1722259 D 546272 CDS YP_002733455.1 225853222 7677000 complement(1722822..1723001) 1 NC_012441.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1723001 rpmF 7677000 rpmF Brucella melitensis ATCC 23457 50S ribosomal protein L32 YP_002733455.1 1722822 R 546272 CDS YP_002733456.1 225853223 7677001 complement(1723161..1723958) 1 NC_012441.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 1723958 mtgA 7677001 mtgA Brucella melitensis ATCC 23457 monofunctional biosynthetic peptidoglycan transglycosylase YP_002733456.1 1723161 R 546272 CDS YP_002733457.1 225853224 7677002 1724082..1724996 1 NC_012441.1 polyprenyl synthetase 1724996 7677002 BMEA_A1827 Brucella melitensis ATCC 23457 polyprenyl synthetase YP_002733457.1 1724082 D 546272 CDS YP_002733458.1 225853225 7677003 complement(1725004..1726266) 1 NC_012441.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1726266 ispG 7677003 ispG Brucella melitensis ATCC 23457 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002733458.1 1725004 R 546272 CDS YP_002733459.1 225853226 7677004 1726434..1727225 1 NC_012441.1 3-hydroxybutyrate dehydrogenase 1727225 7677004 BMEA_A1829 Brucella melitensis ATCC 23457 3-hydroxybutyrate dehydrogenase YP_002733459.1 1726434 D 546272 CDS YP_002733460.1 225853227 7677005 complement(1727243..1728436) 1 NC_012441.1 membrane protein MosC 1728436 7677005 BMEA_A1830 Brucella melitensis ATCC 23457 membrane protein MosC YP_002733460.1 1727243 R 546272 CDS YP_002733461.1 225853228 7677006 complement(1728498..1731974) 1 NC_012441.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1731974 pyc 7677006 pyc Brucella melitensis ATCC 23457 pyruvate carboxylase YP_002733461.1 1728498 R 546272 CDS YP_002733462.1 225853229 7677007 complement(1732240..1733355) 1 NC_012441.1 Leu/Ile/Val-binding protein 1733355 7677007 BMEA_A1832 Brucella melitensis ATCC 23457 Leu/Ile/Val-binding protein YP_002733462.1 1732240 R 546272 CDS YP_002733463.1 225853230 7677008 complement(1733498..1733629) 1 NC_012441.1 hypothetical protein 1733629 7677008 BMEA_A1833 Brucella melitensis ATCC 23457 hypothetical protein YP_002733463.1 1733498 R 546272 CDS YP_002733464.1 225853231 7677009 1733648..1733785 1 NC_012441.1 hypothetical protein 1733785 7677009 BMEA_A1835 Brucella melitensis ATCC 23457 hypothetical protein YP_002733464.1 1733648 D 546272 CDS YP_002733465.1 225853232 7677010 complement(1733976..1735091) 1 NC_012441.1 Leu/Ile/Val-binding protein precursor 1735091 7677010 BMEA_A1836 Brucella melitensis ATCC 23457 Leu/Ile/Val-binding protein precursor YP_002733465.1 1733976 R 546272 CDS YP_002733466.1 225853233 7677011 complement(1735243..1735587) 1 NC_012441.1 hypothetical protein 1735587 7677011 BMEA_A1837 Brucella melitensis ATCC 23457 hypothetical protein YP_002733466.1 1735243 R 546272 CDS YP_002733467.1 225853234 7677012 complement(1735597..1736346) 1 NC_012441.1 hypothetical protein 1736346 7677012 BMEA_A1838 Brucella melitensis ATCC 23457 hypothetical protein YP_002733467.1 1735597 R 546272 CDS YP_002733468.1 225853235 7677013 complement(1736343..1737683) 1 NC_012441.1 ABC transporter 1737683 7677013 BMEA_A1839 Brucella melitensis ATCC 23457 ABC transporter YP_002733468.1 1736343 R 546272 CDS YP_002733469.1 225853236 7677014 complement(1737683..1739062) 1 NC_012441.1 inner-membrane translocator 1739062 7677014 BMEA_A1840 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002733469.1 1737683 R 546272 CDS YP_002733470.1 225853237 7677015 complement(1739065..1739988) 1 NC_012441.1 hypothetical protein 1739988 7677015 BMEA_A1841 Brucella melitensis ATCC 23457 hypothetical protein YP_002733470.1 1739065 R 546272 CDS YP_002733471.1 225853238 7677016 complement(1740267..1741268) 1 NC_012441.1 hydroxyproline-2-epimerase 1741268 7677016 BMEA_A1842 Brucella melitensis ATCC 23457 hydroxyproline-2-epimerase YP_002733471.1 1740267 R 546272 CDS YP_002733472.1 225853239 7677331 1742574..1742759 1 NC_012441.1 hypothetical protein 1742759 7677331 BMEA_A1844 Brucella melitensis ATCC 23457 hypothetical protein YP_002733472.1 1742574 D 546272 CDS YP_002733473.1 225853240 7677332 1742815..1743510 1 NC_012441.1 GntR family transcriptional regulator 1743510 7677332 BMEA_A1845 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733473.1 1742815 D 546272 CDS YP_002733474.1 225853241 7677333 complement(1743583..1744020) 1 NC_012441.1 transcriptional regulator slyA 1744020 7677333 BMEA_A1846 Brucella melitensis ATCC 23457 transcriptional regulator slyA YP_002733474.1 1743583 R 546272 CDS YP_002733475.1 225853242 7677334 complement(1744363..1744770) 1 NC_012441.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1744770 atpC 7677334 atpC Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit epsilon YP_002733475.1 1744363 R 546272 CDS YP_002733476.1 225853243 7677335 complement(1744895..1746460) 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1746460 atpD 7677335 atpD Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit beta YP_002733476.1 1744895 R 546272 CDS YP_002733477.1 225853244 7677336 complement(1746588..1747466) 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1747466 atpG 7677336 atpG Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit gamma YP_002733477.1 1746588 R 546272 CDS YP_002733478.1 225853245 7677337 complement(1747488..1749017) 1 NC_012441.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1749017 atpA 7677337 atpA Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit alpha YP_002733478.1 1747488 R 546272 CDS YP_002733479.1 225853246 7677338 complement(1749017..1749577) 1 NC_012441.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1749577 atpH 7677338 atpH Brucella melitensis ATCC 23457 F0F1 ATP synthase subunit delta YP_002733479.1 1749017 R 546272 CDS YP_002733480.1 225853247 7677339 complement(1749859..1750272) 1 NC_012441.1 hypothetical protein 1750272 7677339 BMEA_A1853 Brucella melitensis ATCC 23457 hypothetical protein YP_002733480.1 1749859 R 546272 CDS YP_002733481.1 225853248 7677340 complement(1750339..1752573) 1 NC_012441.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1752573 priA 7677340 priA Brucella melitensis ATCC 23457 primosome assembly protein PriA YP_002733481.1 1750339 R 546272 CDS YP_002733482.1 225853249 7677341 1752683..1753336 1 NC_012441.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1753336 talC 7677341 talC Brucella melitensis ATCC 23457 putative translaldolase YP_002733482.1 1752683 D 546272 CDS YP_002733483.1 225853250 7677342 complement(1753479..1754060) 1 NC_012441.1 hypothetical protein 1754060 7677342 BMEA_A1856 Brucella melitensis ATCC 23457 hypothetical protein YP_002733483.1 1753479 R 546272 CDS YP_002733484.1 225853251 7677343 complement(1754047..1756680) 1 NC_012441.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1756680 leuS 7677343 leuS Brucella melitensis ATCC 23457 leucyl-tRNA synthetase YP_002733484.1 1754047 R 546272 CDS YP_002733485.1 225853252 7677344 1756803..1757483 1 NC_012441.1 hypothetical protein 1757483 7677344 BMEA_A1858 Brucella melitensis ATCC 23457 hypothetical protein YP_002733485.1 1756803 D 546272 CDS YP_002733486.1 225853253 7677345 complement(1757496..1758026) 1 NC_012441.1 hypothetical protein 1758026 7677345 BMEA_A1859 Brucella melitensis ATCC 23457 hypothetical protein YP_002733486.1 1757496 R 546272 CDS YP_002733487.1 225853254 7677346 complement(1758097..1758384) 1 NC_012441.1 Usg family protein 1758384 7677346 BMEA_A1860 Brucella melitensis ATCC 23457 Usg family protein YP_002733487.1 1758097 R 546272 CDS YP_002733488.1 225853255 7677347 1758725..1760680 1 NC_012441.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1760680 acsA 7677347 acsA Brucella melitensis ATCC 23457 acetyl-CoA synthetase YP_002733488.1 1758725 D 546272 CDS YP_002733489.1 225853256 7677348 complement(1760836..1761054) 1 NC_012441.1 hypothetical protein 1761054 7677348 BMEA_A1862 Brucella melitensis ATCC 23457 hypothetical protein YP_002733489.1 1760836 R 546272 CDS YP_002733490.1 225853257 7677349 1761186..1762163 1 NC_012441.1 putative metalloprotease; heat shock protein HtpX 1762163 7677349 BMEA_A1863 Brucella melitensis ATCC 23457 heat shock protein HtpX YP_002733490.1 1761186 D 546272 CDS YP_002733491.1 225853258 7677350 1762179..1763576 1 NC_012441.1 Fmu domain-containing protein, Sun 1763576 7677350 BMEA_A1864 Brucella melitensis ATCC 23457 Fmu domain-containing protein, Sun YP_002733491.1 1762179 D 546272 CDS YP_002733492.1 225853259 7677351 1763697..1765439 1 NC_012441.1 hypothetical protein 1765439 7677351 BMEA_A1865 Brucella melitensis ATCC 23457 hypothetical protein YP_002733492.1 1763697 D 546272 CDS YP_002733493.1 225853260 7677352 1765546..1767162 1 NC_012441.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1767162 purH 7677352 purH Brucella melitensis ATCC 23457 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002733493.1 1765546 D 546272 CDS YP_002733494.1 225853261 7677354 1768668..1768820 1 NC_012441.1 hypothetical protein 1768820 7677354 BMEA_A1868 Brucella melitensis ATCC 23457 hypothetical protein YP_002733494.1 1768668 D 546272 CDS YP_002733495.1 225853262 7677355 complement(1768798..1773600) 1 NC_012441.1 NAD-glutamate dehydrogenase 1773600 7677355 BMEA_A1869 Brucella melitensis ATCC 23457 NAD-glutamate dehydrogenase YP_002733495.1 1768798 R 546272 CDS YP_002733496.1 225853263 7677356 complement(1773865..1774506) 1 NC_012441.1 hypothetical protein 1774506 7677356 BMEA_A1870 Brucella melitensis ATCC 23457 hypothetical protein YP_002733496.1 1773865 R 546272 CDS YP_002733497.1 225853264 7677357 complement(1774519..1775286) 1 NC_012441.1 hypothetical protein 1775286 7677357 BMEA_A1871 Brucella melitensis ATCC 23457 hypothetical protein YP_002733497.1 1774519 R 546272 CDS YP_002733498.1 225853265 7677358 complement(1775367..1775990) 1 NC_012441.1 LemA family protein 1775990 7677358 BMEA_A1872 Brucella melitensis ATCC 23457 LemA family protein YP_002733498.1 1775367 R 546272 CDS YP_002733499.1 225853266 7677359 complement(1775987..1776160) 1 NC_012441.1 hypothetical protein 1776160 7677359 BMEA_A1873 Brucella melitensis ATCC 23457 hypothetical protein YP_002733499.1 1775987 R 546272 CDS YP_002733500.1 225853267 7677360 complement(1776260..1776631) 1 NC_012441.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1776631 rpsP 7677360 rpsP Brucella melitensis ATCC 23457 30S ribosomal protein S16 YP_002733500.1 1776260 R 546272 CDS YP_002733501.1 225853268 7677361 complement(1776698..1777012) 1 NC_012441.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1777012 7677361 BMEA_A1875 Brucella melitensis ATCC 23457 chorismate mutase YP_002733501.1 1776698 R 546272 CDS YP_002733502.1 225853269 7677362 complement(1777018..1778589) 1 NC_012441.1 signal recognition particle protein 1778589 ffh 7677362 ffh Brucella melitensis ATCC 23457 signal recognition particle protein YP_002733502.1 1777018 R 546272 CDS YP_002733503.1 225853270 7677363 1779024..1779851 1 NC_012441.1 lytic murein transglycosylase 1779851 7677363 BMEA_A1877 Brucella melitensis ATCC 23457 lytic murein transglycosylase YP_002733503.1 1779024 D 546272 CDS YP_002733504.1 225853271 7677364 complement(1779915..1780556) 1 NC_012441.1 carbonic anhydrase 1780556 7677364 BMEA_A1878 Brucella melitensis ATCC 23457 carbonic anhydrase YP_002733504.1 1779915 R 546272 CDS YP_002733505.1 225853272 7677365 complement(1780730..1781626) 1 NC_012441.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1781626 7677365 BMEA_A1879 Brucella melitensis ATCC 23457 pyridoxamine kinase YP_002733505.1 1780730 R 546272 CDS YP_002733506.1 225853273 7677366 complement(1781628..1781915) 1 NC_012441.1 hypothetical protein 1781915 7677366 BMEA_A1880 Brucella melitensis ATCC 23457 hypothetical protein YP_002733506.1 1781628 R 546272 CDS YP_002733507.1 225853274 7677367 complement(1782189..1783685) 1 NC_012441.1 methylmalonate-semialdehyde dehydrogenase 1783685 mmsA 7677367 mmsA Brucella melitensis ATCC 23457 methylmalonate-semialdehyde dehydrogenase YP_002733507.1 1782189 R 546272 CDS YP_002733508.1 225853275 7677368 1783792..1784718 1 NC_012441.1 LysR family transcriptional regulator 1784718 7677368 BMEA_A1882 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002733508.1 1783792 D 546272 CDS YP_002733509.1 225853276 7677369 complement(1784929..1785573) 1 NC_012441.1 hypothetical protein 1785573 7677369 BMEA_A1883 Brucella melitensis ATCC 23457 hypothetical protein YP_002733509.1 1784929 R 546272 CDS YP_002733510.1 225853277 7677370 complement(1785641..1785895) 1 NC_012441.1 hypothetical protein 1785895 7677370 BMEA_A1885 Brucella melitensis ATCC 23457 hypothetical protein YP_002733510.1 1785641 R 546272 CDS YP_002733511.1 225853278 7677371 complement(1786011..1786547) 1 NC_012441.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1786547 7677371 BMEA_A1886 Brucella melitensis ATCC 23457 dinucleoside polyphosphate hydrolase YP_002733511.1 1786011 R 546272 CDS YP_002733512.1 225853279 7677372 complement(1786765..1788093) 1 NC_012441.1 carboxyl-terminal protease 1788093 7677372 BMEA_A1887 Brucella melitensis ATCC 23457 carboxyl-terminal protease YP_002733512.1 1786765 R 546272 CDS YP_002733513.1 225853280 7677373 complement(1788083..1789432) 1 NC_012441.1 leucine zipper protein 1 1789432 7677373 BMEA_A1888 Brucella melitensis ATCC 23457 leucine zipper protein 1 YP_002733513.1 1788083 R 546272 CDS YP_002733514.1 225853281 7677374 complement(1789545..1790444) 1 NC_012441.1 hypothetical protein 1790444 7677374 BMEA_A1889 Brucella melitensis ATCC 23457 hypothetical protein YP_002733514.1 1789545 R 546272 CDS YP_002733515.1 225853282 7677375 complement(1790562..1791086) 1 NC_012441.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1791086 7677375 BMEA_A1890 Brucella melitensis ATCC 23457 rRNA large subunit methyltransferase YP_002733515.1 1790562 R 546272 CDS YP_002733516.1 225853283 7677376 complement(1791105..1791476) 1 NC_012441.1 iojap-like protein 1791476 7677376 BMEA_A1891 Brucella melitensis ATCC 23457 iojap-like protein YP_002733516.1 1791105 R 546272 CDS YP_002733517.1 225853284 7677377 complement(1791639..1792313) 1 NC_012441.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1792313 nadD 7677377 nadD Brucella melitensis ATCC 23457 nicotinic acid mononucleotide adenylyltransferase YP_002733517.1 1791639 R 546272 CDS YP_002733518.1 225853285 7677378 complement(1792313..1793596) 1 NC_012441.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1793596 proA 7677378 proA Brucella melitensis ATCC 23457 gamma-glutamyl phosphate reductase YP_002733518.1 1792313 R 546272 CDS YP_002733519.1 225853286 7677379 complement(1793606..1794742) 1 NC_012441.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1794742 proB 7677379 proB Brucella melitensis ATCC 23457 gamma-glutamyl kinase YP_002733519.1 1793606 R 546272 CDS YP_002733520.1 225853287 7677380 complement(1794770..1795795) 1 NC_012441.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1795795 7677380 BMEA_A1895 Brucella melitensis ATCC 23457 GTPase ObgE YP_002733520.1 1794770 R 546272 CDS YP_002733521.1 225853288 7677381 complement(1797104..1797661) 1 NC_012441.1 N-acetyltransferase GCN5 1797661 7677381 BMEA_A1896 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733521.1 1797104 R 546272 CDS YP_002733522.1 225853289 7677382 complement(1797924..1798406) 1 NC_012441.1 N-acetyltransferase GCN5 1798406 7677382 BMEA_A1897 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733522.1 1797924 R 546272 CDS YP_002733523.1 225853290 7677383 complement(1798485..1798754) 1 NC_012441.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1798754 rpmA 7677383 rpmA Brucella melitensis ATCC 23457 50S ribosomal protein L27 YP_002733523.1 1798485 R 546272 CDS YP_002733524.1 225853291 7677384 complement(1798780..1799208) 1 NC_012441.1 50S ribosomal protein L21 1799208 rplU 7677384 rplU Brucella melitensis ATCC 23457 50S ribosomal protein L21 YP_002733524.1 1798780 R 546272 CDS YP_002733525.1 225853292 7677386 1799726..1800604 1 NC_012441.1 transposase and inactivated derivatives-like protein 1800604 7677386 BMEA_A1901 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002733525.1 1799726 D 546272 CDS YP_002733526.1 225853293 7677387 1800821..1802773 1 NC_012441.1 hypothetical protein 1802773 7677387 BMEA_A1902 Brucella melitensis ATCC 23457 hypothetical protein YP_002733526.1 1800821 D 546272 CDS YP_002733527.1 225853294 7677388 1802770..1803444 1 NC_012441.1 hypothetical protein 1803444 7677388 BMEA_A1903 Brucella melitensis ATCC 23457 hypothetical protein YP_002733527.1 1802770 D 546272 CDS YP_002733528.1 225853295 7677389 1803857..1803970 1 NC_012441.1 hypothetical protein 1803970 7677389 BMEA_A1904 Brucella melitensis ATCC 23457 hypothetical protein YP_002733528.1 1803857 D 546272 CDS YP_002733529.1 225853296 7677390 complement(1804003..1804689) 1 NC_012441.1 transposase and inactivated derivatives-like protein 1804689 7677390 BMEA_A1905 Brucella melitensis ATCC 23457 transposase and inactivated derivatives-like protein YP_002733529.1 1804003 R 546272 CDS YP_002733530.1 225853297 7677391 complement(1804800..1806239) 1 NC_012441.1 hypothetical protein 1806239 7677391 BMEA_A1906 Brucella melitensis ATCC 23457 hypothetical protein YP_002733530.1 1804800 R 546272 CDS YP_002733531.1 225853298 7677392 complement(1806415..1807089) 1 NC_012441.1 hypothetical protein 1807089 7677392 BMEA_A1907 Brucella melitensis ATCC 23457 hypothetical protein YP_002733531.1 1806415 R 546272 CDS YP_002733532.1 225853299 7677393 1807407..1807574 1 NC_012441.1 hypothetical protein 1807574 7677393 BMEA_A1908 Brucella melitensis ATCC 23457 hypothetical protein YP_002733532.1 1807407 D 546272 CDS YP_002733533.1 225853300 7677560 1807962..1808114 1 NC_012441.1 hypothetical protein 1808114 7677560 BMEA_A1911 Brucella melitensis ATCC 23457 hypothetical protein YP_002733533.1 1807962 D 546272 CDS YP_002733534.1 225853301 7677565 1814227..1816182 1 NC_012441.1 peptidase M23B 1816182 7677565 BMEA_A1916 Brucella melitensis ATCC 23457 peptidase M23B YP_002733534.1 1814227 D 546272 CDS YP_002733535.1 225853302 7677566 complement(1816250..1817476) 1 NC_012441.1 ErfK/YbiS/YcfS/YnhG family protein 1817476 7677566 BMEA_A1917 Brucella melitensis ATCC 23457 ErfK/YbiS/YcfS/YnhG family protein YP_002733535.1 1816250 R 546272 CDS YP_002733536.1 225853303 7677567 complement(1818149..1820773) 1 NC_012441.1 ATP-dependent chaperone ClpB 1820773 clpB 7677567 clpB Brucella melitensis ATCC 23457 ATP-dependent chaperone ClpB YP_002733536.1 1818149 R 546272 CDS YP_002733537.1 225853304 7677568 complement(1820972..1821730) 1 NC_012441.1 hypothetical protein 1821730 7677568 BMEA_A1919 Brucella melitensis ATCC 23457 hypothetical protein YP_002733537.1 1820972 R 546272 CDS YP_002733538.1 225853305 7677569 complement(1821711..1821983) 1 NC_012441.1 hypothetical protein 1821983 7677569 BMEA_A1920 Brucella melitensis ATCC 23457 hypothetical protein YP_002733538.1 1821711 R 546272 CDS YP_002733539.1 225853306 7677570 1822045..1822191 1 NC_012441.1 hypothetical protein 1822191 7677570 BMEA_A1921 Brucella melitensis ATCC 23457 hypothetical protein YP_002733539.1 1822045 D 546272 CDS YP_002733540.1 225853307 7677571 complement(1822175..1823062) 1 NC_012441.1 methyltransferase, HemK family protein 1823062 hemK 7677571 hemK Brucella melitensis ATCC 23457 methyltransferase, HemK family protein YP_002733540.1 1822175 R 546272 CDS YP_002733541.1 225853308 7677572 complement(1823059..1824138) 1 NC_012441.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1824138 prfA 7677572 prfA Brucella melitensis ATCC 23457 peptide chain release factor 1 YP_002733541.1 1823059 R 546272 CDS YP_002733542.1 225853309 7677573 complement(1824335..1826605) 1 NC_012441.1 phosphoenolpyruvate-protein phosphotransferase 1826605 ptsI 7677573 ptsI Brucella melitensis ATCC 23457 phosphoenolpyruvate-protein phosphotransferase YP_002733542.1 1824335 R 546272 CDS YP_002733543.1 225853310 7677574 complement(1826933..1828204) 1 NC_012441.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1828204 7677574 BMEA_A1925 Brucella melitensis ATCC 23457 aspartate kinase YP_002733543.1 1826933 R 546272 CDS YP_002733544.1 225853311 7677575 1828422..1829168 1 NC_012441.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1829168 ubiG 7677575 ubiG Brucella melitensis ATCC 23457 3-demethylubiquinone-9 3-methyltransferase YP_002733544.1 1828422 D 546272 CDS YP_002733545.1 225853312 7677576 complement(1829174..1830067) 1 NC_012441.1 hypothetical protein 1830067 7677576 BMEA_A1927 Brucella melitensis ATCC 23457 hypothetical protein YP_002733545.1 1829174 R 546272 CDS YP_002733546.1 225853313 7677577 complement(1830095..1830520) 1 NC_012441.1 hypothetical protein 1830520 7677577 BMEA_A1928 Brucella melitensis ATCC 23457 hypothetical protein YP_002733546.1 1830095 R 546272 CDS YP_002733547.1 225853314 7677578 complement(1830526..1831380) 1 NC_012441.1 nitrilase/cyanide hydratase and apolipoprotein n-acyltransferase 1831380 7677578 BMEA_A1929 Brucella melitensis ATCC 23457 nitrilase/cyanide hydratase and apolipoprotein n-acyltransferase YP_002733547.1 1830526 R 546272 CDS YP_002733548.1 225853315 7677579 complement(1831391..1831657) 1 NC_012441.1 glutaredoxin 3 1831657 grxC 7677579 grxC Brucella melitensis ATCC 23457 glutaredoxin 3 YP_002733548.1 1831391 R 546272 CDS YP_002733549.1 225853316 7677580 1831641..1831763 1 NC_012441.1 hypothetical protein 1831763 7677580 BMEA_A1931 Brucella melitensis ATCC 23457 hypothetical protein YP_002733549.1 1831641 D 546272 CDS YP_002733550.1 225853317 7677581 complement(1831741..1832529) 1 NC_012441.1 competence protein F 1832529 7677581 BMEA_A1932 Brucella melitensis ATCC 23457 competence protein F YP_002733550.1 1831741 R 546272 CDS YP_002733551.1 225853318 7677582 1832712..1833605 1 NC_012441.1 methyltransferase type 11 1833605 7677582 BMEA_A1933 Brucella melitensis ATCC 23457 methyltransferase type 11 YP_002733551.1 1832712 D 546272 CDS YP_002733552.1 225853319 7677583 1833744..1834982 1 NC_012441.1 major facilitator superfamily protein 1834982 7677583 BMEA_A1935 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002733552.1 1833744 D 546272 CDS YP_002733553.1 225853320 7677584 complement(1835008..1835487) 1 NC_012441.1 hypothetical protein 1835487 7677584 BMEA_A1936 Brucella melitensis ATCC 23457 hypothetical protein YP_002733553.1 1835008 R 546272 CDS YP_002733554.1 225853321 7677585 complement(1835903..1837474) 1 NC_012441.1 HemY domain-containing protein 1837474 7677585 BMEA_A1937 Brucella melitensis ATCC 23457 HemY domain-containing protein YP_002733554.1 1835903 R 546272 CDS YP_002733555.1 225853322 7677586 complement(1837487..1838863) 1 NC_012441.1 hypothetical protein 1838863 7677586 BMEA_A1938 Brucella melitensis ATCC 23457 hypothetical protein YP_002733555.1 1837487 R 546272 CDS YP_002733556.1 225853323 7677587 complement(1838946..1839653) 1 NC_012441.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; uroporphyrinogen-III synthase 1839653 7677587 BMEA_A1939 Brucella melitensis ATCC 23457 uroporphyrinogen-III synthase YP_002733556.1 1838946 R 546272 CDS YP_002733557.1 225853324 7677588 complement(1839677..1840621) 1 NC_012441.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1840621 hemC 7677588 hemC Brucella melitensis ATCC 23457 porphobilinogen deaminase YP_002733557.1 1839677 R 546272 CDS YP_002733558.1 225853325 7677589 1840740..1841819 1 NC_012441.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1841819 7677589 BMEA_A1941 Brucella melitensis ATCC 23457 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002733558.1 1840740 D 546272 CDS YP_002733559.1 225853326 7677590 1841816..1842796 1 NC_012441.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1842796 7677590 BMEA_A1942 Brucella melitensis ATCC 23457 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002733559.1 1841816 D 546272 CDS YP_002733560.1 225853327 7677591 1842798..1843088 1 NC_012441.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1843088 7677591 BMEA_A1943 Brucella melitensis ATCC 23457 YciI-like protein YP_002733560.1 1842798 D 546272 CDS YP_002733561.1 225853328 7677592 1843101..1843529 1 NC_012441.1 hypothetical protein 1843529 7677592 BMEA_A1944 Brucella melitensis ATCC 23457 hypothetical protein YP_002733561.1 1843101 D 546272 CDS YP_002733562.1 225853329 7677593 1843481..1844185 1 NC_012441.1 hypothetical protein 1844185 7677593 BMEA_A1945 Brucella melitensis ATCC 23457 hypothetical protein YP_002733562.1 1843481 D 546272 CDS YP_002733563.1 225853330 7677594 complement(1844231..1845088) 1 NC_012441.1 hypothetical protein 1845088 7677594 BMEA_A1946 Brucella melitensis ATCC 23457 hypothetical protein YP_002733563.1 1844231 R 546272 CDS YP_002733564.1 225853331 7677595 1845204..1846697 1 NC_012441.1 GntR family transcriptional regulator 1846697 7677595 BMEA_A1947 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733564.1 1845204 D 546272 CDS YP_002733565.1 225853332 7677596 complement(1846759..1849212) 1 NC_012441.1 DNA translocase ftsK 1849212 7677596 BMEA_A1948 Brucella melitensis ATCC 23457 DNA translocase ftsK YP_002733565.1 1846759 R 546272 CDS YP_002733566.1 225853333 7677597 complement(1849422..1850723) 1 NC_012441.1 ammonium transporter 1850723 amt 7677597 amt Brucella melitensis ATCC 23457 ammonium transporter YP_002733566.1 1849422 R 546272 CDS YP_002733567.1 225853334 7677598 1850697..1850855 1 NC_012441.1 hypothetical protein 1850855 7677598 BMEA_A1950 Brucella melitensis ATCC 23457 hypothetical protein YP_002733567.1 1850697 D 546272 CDS YP_002733568.1 225853335 7677599 complement(1850946..1851899) 1 NC_012441.1 acyl-CoA thioesterase II 1851899 tesB 7677599 tesB Brucella melitensis ATCC 23457 acyl-CoA thioesterase II YP_002733568.1 1850946 R 546272 CDS YP_002733569.1 225853336 7677600 1852068..1853312 1 NC_012441.1 2-octaprenyl-6-methoxyphenyl hydroxylase 1853312 7677600 BMEA_A1952 Brucella melitensis ATCC 23457 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002733569.1 1852068 D 546272 CDS YP_002733570.1 225853337 7677601 complement(1853398..1853769) 1 NC_012441.1 glyoxalase/bleomycin resistance protein/dioxygenase 1853769 7677601 BMEA_A1953 Brucella melitensis ATCC 23457 glyoxalase/bleomycin resistance protein/dioxygenase YP_002733570.1 1853398 R 546272 CDS YP_002733571.1 225853338 7677602 complement(1854138..1854917) 1 NC_012441.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1854917 7677602 BMEA_A1955 Brucella melitensis ATCC 23457 succinate dehydrogenase iron-sulfur subunit YP_002733571.1 1854138 R 546272 CDS YP_002733572.1 225853339 7677603 complement(1854933..1856774) 1 NC_012441.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1856774 sdhA 7677603 sdhA Brucella melitensis ATCC 23457 succinate dehydrogenase flavoprotein subunit YP_002733572.1 1854933 R 546272 CDS YP_002733573.1 225853340 7677604 complement(1856782..1857177) 1 NC_012441.1 succinate dehydrogenase hydrophobic membrane anchor protein 1857177 sdhD 7677604 sdhD Brucella melitensis ATCC 23457 succinate dehydrogenase hydrophobic membrane anchor protein YP_002733573.1 1856782 R 546272 CDS YP_002733574.1 225853341 7677605 complement(1857191..1857589) 1 NC_012441.1 succinate dehydrogenase cytochrome b556 subunit 1857589 sdhC 7677605 sdhC Brucella melitensis ATCC 23457 succinate dehydrogenase cytochrome b556 subunit YP_002733574.1 1857191 R 546272 CDS YP_002733575.1 225853342 7677606 1857631..1857825 1 NC_012441.1 hypothetical protein 1857825 7677606 BMEA_A1959 Brucella melitensis ATCC 23457 hypothetical protein YP_002733575.1 1857631 D 546272 CDS YP_002733576.1 225853343 7677607 complement(1857934..1858392) 1 NC_012441.1 hypothetical protein 1858392 7677607 BMEA_A1960 Brucella melitensis ATCC 23457 hypothetical protein YP_002733576.1 1857934 R 546272 CDS YP_002733577.1 225853344 7677608 complement(1858649..1860058) 1 NC_012441.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1860058 leuC 7677608 leuC Brucella melitensis ATCC 23457 isopropylmalate isomerase large subunit YP_002733577.1 1858649 R 546272 CDS YP_002733578.1 225853345 7677609 complement(1860269..1860706) 1 NC_012441.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1860706 rplS 7677609 rplS Brucella melitensis ATCC 23457 50S ribosomal protein L19 YP_002733578.1 1860269 R 546272 CDS YP_002733579.1 225853346 7677611 complement(1862612..1862863) 1 NC_012441.1 hypothetical protein 1862863 7677611 BMEA_A1965 Brucella melitensis ATCC 23457 hypothetical protein YP_002733579.1 1862612 R 546272 CDS YP_002733580.1 225853347 7677612 complement(1862860..1863270) 1 NC_012441.1 hypothetical protein 1863270 7677612 BMEA_A1966 Brucella melitensis ATCC 23457 hypothetical protein YP_002733580.1 1862860 R 546272 CDS YP_002733581.1 225853348 7677613 complement(1863263..1863625) 1 NC_012441.1 hypothetical protein 1863625 7677613 BMEA_A1967 Brucella melitensis ATCC 23457 hypothetical protein YP_002733581.1 1863263 R 546272 CDS YP_002733582.1 225853349 7677614 complement(1863622..1863945) 1 NC_012441.1 NIPSNAP family protein 1863945 7677614 BMEA_A1968 Brucella melitensis ATCC 23457 NIPSNAP family protein YP_002733582.1 1863622 R 546272 CDS YP_002733583.1 225853350 7677615 1864016..1864681 1 NC_012441.1 ArsR family transcriptional regulator 1864681 7677615 BMEA_A1969 Brucella melitensis ATCC 23457 ArsR family transcriptional regulator YP_002733583.1 1864016 D 546272 CDS YP_002733584.1 225853351 7677616 complement(1864816..1865550) 1 NC_012441.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1865550 trmD 7677616 trmD Brucella melitensis ATCC 23457 tRNA (guanine-N(1)-)-methyltransferase YP_002733584.1 1864816 R 546272 CDS YP_002733585.1 225853352 7677617 complement(1865547..1866116) 1 NC_012441.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1866116 rimM 7677617 rimM Brucella melitensis ATCC 23457 16S rRNA-processing protein RimM YP_002733585.1 1865547 R 546272 CDS YP_002733586.1 225853353 7677618 complement(1866153..1866278) 1 NC_012441.1 hypothetical protein 1866278 7677618 BMEA_A1972 Brucella melitensis ATCC 23457 hypothetical protein YP_002733586.1 1866153 R 546272 CDS YP_002733587.1 225853354 7677619 1866340..1867287 1 NC_012441.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1867287 xerC 7677619 xerC Brucella melitensis ATCC 23457 site-specific tyrosine recombinase XerC YP_002733587.1 1866340 D 546272 CDS YP_002733588.1 225853355 7677620 1867341..1868342 1 NC_012441.1 GumN family protein 1868342 7677620 BMEA_A1974 Brucella melitensis ATCC 23457 GumN family protein YP_002733588.1 1867341 D 546272 CDS YP_002733589.1 225853356 7677621 complement(1868546..1869949) 1 NC_012441.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1869949 lpdA 7677621 lpdA Brucella melitensis ATCC 23457 dihydrolipoamide dehydrogenase YP_002733589.1 1868546 R 546272 CDS YP_002733590.1 225853357 7677622 complement(1870118..1870660) 1 NC_012441.1 hypothetical protein 1870660 7677622 BMEA_A1976 Brucella melitensis ATCC 23457 hypothetical protein YP_002733590.1 1870118 R 546272 CDS YP_002733591.1 225853358 7677623 complement(1870731..1871369) 1 NC_012441.1 lysine exporter protein lYSE/YGGA 1871369 7677623 BMEA_A1977 Brucella melitensis ATCC 23457 lysine exporter protein lYSE/YGGA YP_002733591.1 1870731 R 546272 CDS YP_002733592.1 225853359 7677624 complement(1871411..1871824) 1 NC_012441.1 hypothetical protein 1871824 7677624 BMEA_A1978 Brucella melitensis ATCC 23457 hypothetical protein YP_002733592.1 1871411 R 546272 CDS YP_002733593.1 225853360 7677625 complement(1871834..1873060) 1 NC_012441.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1873060 sucB 7677625 sucB Brucella melitensis ATCC 23457 dihydrolipoamide succinyltransferase YP_002733593.1 1871834 R 546272 CDS YP_002733594.1 225853361 7677626 complement(1873122..1876136) 1 NC_012441.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1876136 sucA 7677626 sucA Brucella melitensis ATCC 23457 2-oxoglutarate dehydrogenase E1 component YP_002733594.1 1873122 R 546272 CDS YP_002733595.1 225853362 7677627 1876273..1876422 1 NC_012441.1 hypothetical protein 1876422 7677627 BMEA_A1981 Brucella melitensis ATCC 23457 hypothetical protein YP_002733595.1 1876273 D 546272 CDS YP_002733596.1 225853363 7677628 complement(1876412..1877314) 1 NC_012441.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1877314 7677628 BMEA_A1982 Brucella melitensis ATCC 23457 succinyl-CoA synthetase subunit alpha YP_002733596.1 1876412 R 546272 CDS YP_002733597.1 225853364 7677629 complement(1877318..1878514) 1 NC_012441.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1878514 7677629 BMEA_A1983 Brucella melitensis ATCC 23457 succinyl-CoA synthetase subunit beta YP_002733597.1 1877318 R 546272 CDS YP_002733598.1 225853365 7677630 complement(1878621..1879583) 1 NC_012441.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1879583 mdh 7677630 mdh Brucella melitensis ATCC 23457 malate dehydrogenase YP_002733598.1 1878621 R 546272 CDS YP_002733599.1 225853366 7677631 complement(1879703..1879945) 1 NC_012441.1 hypothetical protein 1879945 7677631 BMEA_A1985 Brucella melitensis ATCC 23457 hypothetical protein YP_002733599.1 1879703 R 546272 CDS YP_002733600.1 225853367 7677632 complement(1880022..1881185) 1 NC_012441.1 AFG1 family ATPase 1881185 7677632 BMEA_A1986 Brucella melitensis ATCC 23457 AFG1 family ATPase YP_002733600.1 1880022 R 546272 CDS YP_002733601.1 225853368 7677633 complement(1881305..1881838) 1 NC_012441.1 hypothetical protein 1881838 7677633 BMEA_A1987 Brucella melitensis ATCC 23457 hypothetical protein YP_002733601.1 1881305 R 546272 CDS YP_002733602.1 225853369 7677634 complement(1881967..1882170) 1 NC_012441.1 hypothetical protein 1882170 7677634 BMEA_A1988 Brucella melitensis ATCC 23457 hypothetical protein YP_002733602.1 1881967 R 546272 CDS YP_002733603.1 225853370 7677635 1882201..1883112 1 NC_012441.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1883112 dapF 7677635 dapF Brucella melitensis ATCC 23457 diaminopimelate epimerase YP_002733603.1 1882201 D 546272 CDS YP_002733604.1 225853371 7677636 1883112..1884395 1 NC_012441.1 MiaB-like tRNA modifying enzyme 1884395 7677636 BMEA_A1990 Brucella melitensis ATCC 23457 MiaB-like tRNA modifying enzyme YP_002733604.1 1883112 D 546272 CDS YP_002733605.1 225853372 7677637 1884417..1885814 1 NC_012441.1 signal recognition particle-docking protein FtsY 1885814 ftsY 7677637 ftsY Brucella melitensis ATCC 23457 signal recognition particle-docking protein FtsY YP_002733605.1 1884417 D 546272 CDS YP_002733606.1 225853373 7677638 1885814..1886476 1 NC_012441.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1886476 ispZ 7677638 ispZ Brucella melitensis ATCC 23457 intracellular septation protein A YP_002733606.1 1885814 D 546272 CDS YP_002733607.1 225853374 7677721 1886500..1887282 1 NC_012441.1 hydroxyacylglutathione hydrolase 1887282 gloB 7677721 gloB Brucella melitensis ATCC 23457 hydroxyacylglutathione hydrolase YP_002733607.1 1886500 D 546272 CDS YP_002733608.1 225853375 7677722 1887329..1887820 1 NC_012441.1 hypothetical protein 1887820 7677722 BMEA_A1994 Brucella melitensis ATCC 23457 hypothetical protein YP_002733608.1 1887329 D 546272 CDS YP_002733609.1 225853376 7677723 complement(1887885..1888190) 1 NC_012441.1 hypothetical protein 1888190 7677723 BMEA_A1995 Brucella melitensis ATCC 23457 hypothetical protein YP_002733609.1 1887885 R 546272 CDS YP_002733610.1 225853377 7677724 complement(1888302..1888718) 1 NC_012441.1 mutator MutT protein 1888718 7677724 BMEA_A1996 Brucella melitensis ATCC 23457 mutator MutT protein YP_002733610.1 1888302 R 546272 CDS YP_002733611.1 225853378 7677725 complement(1888715..1889506) 1 NC_012441.1 N-acetyltransferase GCN5 1889506 7677725 BMEA_A1997 Brucella melitensis ATCC 23457 N-acetyltransferase GCN5 YP_002733611.1 1888715 R 546272 CDS YP_002733612.1 225853379 7677726 complement(1889564..1890805) 1 NC_012441.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 1890805 argJ 7677726 argJ Brucella melitensis ATCC 23457 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_002733612.1 1889564 R 546272 CDS YP_002733613.1 225853380 7677727 complement(1891039..1891182) 1 NC_012441.1 hypothetical protein 1891182 7677727 BMEA_A1999 Brucella melitensis ATCC 23457 hypothetical protein YP_002733613.1 1891039 R 546272 CDS YP_002733614.1 225853381 7677728 complement(1891243..1892238) 1 NC_012441.1 PpiC-type peptidyl-prolyl cis-trans isomerase 1892238 7677728 BMEA_A2000 Brucella melitensis ATCC 23457 PpiC-type peptidyl-prolyl cis-trans isomerase YP_002733614.1 1891243 R 546272 CDS YP_002733615.1 225853382 7677729 complement(1892366..1892533) 1 NC_012441.1 hypothetical protein 1892533 7677729 BMEA_A2001 Brucella melitensis ATCC 23457 hypothetical protein YP_002733615.1 1892366 R 546272 CDS YP_002733616.1 225853383 7677730 1892577..1895297 1 NC_012441.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1895297 secA 7677730 secA Brucella melitensis ATCC 23457 preprotein translocase subunit SecA YP_002733616.1 1892577 D 546272 CDS YP_002733617.1 225853384 7677731 1895325..1895465 1 NC_012441.1 hypothetical protein 1895465 7677731 BMEA_A2003 Brucella melitensis ATCC 23457 hypothetical protein YP_002733617.1 1895325 D 546272 CDS YP_002733618.1 225853385 7677732 1896074..1897360 1 NC_012441.1 hypothetical protein 1897360 7677732 BMEA_A2004 Brucella melitensis ATCC 23457 hypothetical protein YP_002733618.1 1896074 D 546272 CDS YP_002733619.1 225853386 7677733 1897529..1899163 1 NC_012441.1 sulfatase 1899163 7677733 BMEA_A2005 Brucella melitensis ATCC 23457 sulfatase YP_002733619.1 1897529 D 546272 CDS YP_002733620.1 225853387 7677734 1899517..1899618 1 NC_012441.1 hypothetical protein 1899618 7677734 BMEA_A2006 Brucella melitensis ATCC 23457 hypothetical protein YP_002733620.1 1899517 D 546272 CDS YP_002733621.1 225853388 7677736 complement(1900359..1901315) 1 NC_012441.1 regulatory protein 1901315 7677736 BMEA_A2008 Brucella melitensis ATCC 23457 regulatory protein YP_002733621.1 1900359 R 546272 CDS YP_002733622.1 225853389 7677737 complement(1901355..1901540) 1 NC_012441.1 hypothetical protein 1901540 7677737 BMEA_A2009 Brucella melitensis ATCC 23457 hypothetical protein YP_002733622.1 1901355 R 546272 CDS YP_002733623.1 225853390 7677739 1902538..1903236 1 NC_012441.1 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 1903236 7677739 BMEA_A2011 Brucella melitensis ATCC 23457 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease YP_002733623.1 1902538 D 546272 CDS YP_002733624.1 225853391 7677740 1903241..1903963 1 NC_012441.1 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 1903963 7677740 BMEA_A2012 Brucella melitensis ATCC 23457 His/Glu/Gln/Arg/opine family amino acid ABC transporter permease YP_002733624.1 1903241 D 546272 CDS YP_002733625.1 225853392 7677741 1903960..1904775 1 NC_012441.1 octopine permease ATP-binding protein P 1904775 7677741 BMEA_A2013 Brucella melitensis ATCC 23457 octopine permease ATP-binding protein P YP_002733625.1 1903960 D 546272 CDS YP_002733626.1 225853393 7677742 1904796..1905809 1 NC_012441.1 proclavaminate amidinohydrolase 1905809 7677742 BMEA_A2014 Brucella melitensis ATCC 23457 proclavaminate amidinohydrolase YP_002733626.1 1904796 D 546272 CDS YP_002733627.1 225853394 7677743 1905818..1907269 1 NC_012441.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1907269 7677743 BMEA_A2015 Brucella melitensis ATCC 23457 aspartate ammonia-lyase YP_002733627.1 1905818 D 546272 CDS YP_002733628.1 225853395 7677744 1907253..1908008 1 NC_012441.1 glutamate/glutamine/aspartate/asparagine transport ATP-binding protein bztD 1908008 7677744 BMEA_A2016 Brucella melitensis ATCC 23457 glutamate/glutamine/aspartate/asparagine transport ATP-binding protein bztD YP_002733628.1 1907253 D 546272 CDS YP_002733629.1 225853396 7677745 1908017..1909015 1 NC_012441.1 L-asparaginase 1909015 7677745 BMEA_A2017 Brucella melitensis ATCC 23457 L-asparaginase YP_002733629.1 1908017 D 546272 CDS YP_002733630.1 225853397 7677746 complement(1909152..1909835) 1 NC_012441.1 GntR family transcriptional regulator 1909835 7677746 BMEA_A2018 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733630.1 1909152 R 546272 CDS YP_002733631.1 225853398 7677747 complement(1909905..1910849) 1 NC_012441.1 L-asparaginase 1910849 7677747 BMEA_A2019 Brucella melitensis ATCC 23457 L-asparaginase YP_002733631.1 1909905 R 546272 CDS YP_002733632.1 225853399 7677748 1910927..1912234 1 NC_012441.1 major facilitator superfamily protein 1912234 7677748 BMEA_A2020 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002733632.1 1910927 D 546272 CDS YP_002733633.1 225853400 7677749 complement(1912721..1912873) 1 NC_012441.1 hypothetical protein 1912873 7677749 BMEA_A2021 Brucella melitensis ATCC 23457 hypothetical protein YP_002733633.1 1912721 R 546272 CDS YP_002733634.1 225853401 7677750 complement(1912920..1914203) 1 NC_012441.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase 1914203 7677750 BMEA_A2022 Brucella melitensis ATCC 23457 methionine gamma-lyase YP_002733634.1 1912920 R 546272 CDS YP_002733635.1 225853402 7677751 complement(1914383..1914832) 1 NC_012441.1 UspA domain-containing protein 1914832 7677751 BMEA_A2023 Brucella melitensis ATCC 23457 UspA domain-containing protein YP_002733635.1 1914383 R 546272 CDS YP_002733636.1 225853403 7677752 1915052..1916062 1 NC_012441.1 cysteine synthase A 1916062 cysK 7677752 cysK Brucella melitensis ATCC 23457 cysteine synthase A YP_002733636.1 1915052 D 546272 CDS YP_002733637.1 225853404 7677753 complement(1916144..1916392) 1 NC_012441.1 hypothetical protein 1916392 7677753 BMEA_A2025 Brucella melitensis ATCC 23457 hypothetical protein YP_002733637.1 1916144 R 546272 CDS YP_002733638.1 225853405 7677754 complement(1916552..1917427) 1 NC_012441.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 1917427 7677754 BMEA_A2026 Brucella melitensis ATCC 23457 3-hydroxybutyryl-CoA dehydrogenase YP_002733638.1 1916552 R 546272 CDS YP_002733639.1 225853406 7677755 complement(1917911..1918840) 1 NC_012441.1 hypothetical protein 1918840 7677755 BMEA_A2027 Brucella melitensis ATCC 23457 hypothetical protein YP_002733639.1 1917911 R 546272 CDS YP_002733640.1 225853407 7677756 complement(1918993..1919739) 1 NC_012441.1 electron transfer flavoprotein subunit beta 1919739 7677756 BMEA_A2028 Brucella melitensis ATCC 23457 electron transfer flavoprotein subunit beta YP_002733640.1 1918993 R 546272 CDS YP_002733641.1 225853408 7677757 1920075..1920773 1 NC_012441.1 ExsB protein 1920773 7677757 BMEA_A2029 Brucella melitensis ATCC 23457 ExsB protein YP_002733641.1 1920075 D 546272 CDS YP_002733642.1 225853409 7677758 1920773..1921138 1 NC_012441.1 queuosine biosynthesis protein QueD 1921138 queD 7677758 queD Brucella melitensis ATCC 23457 queuosine biosynthesis protein QueD YP_002733642.1 1920773 D 546272 CDS YP_002733643.1 225853410 7677759 1921138..1921893 1 NC_012441.1 radical SAM domain-containing protein 1921893 queE 7677759 queE Brucella melitensis ATCC 23457 radical SAM domain-containing protein YP_002733643.1 1921138 D 546272 CDS YP_002733644.1 225853411 7677760 complement(1922030..1922617) 1 NC_012441.1 ATP:cobalamin adenosyltransferase 1922617 7677760 BMEA_A2032 Brucella melitensis ATCC 23457 ATP:cobalamin adenosyltransferase YP_002733644.1 1922030 R 546272 CDS YP_002733645.1 225853412 7677761 complement(1922619..1922822) 1 NC_012441.1 hypothetical protein 1922822 7677761 BMEA_A2033 Brucella melitensis ATCC 23457 hypothetical protein YP_002733645.1 1922619 R 546272 CDS YP_002733646.1 225853413 7677762 complement(1922852..1923694) 1 NC_012441.1 short chain dehydrogenase 1923694 7677762 BMEA_A2034 Brucella melitensis ATCC 23457 short chain dehydrogenase YP_002733646.1 1922852 R 546272 CDS YP_002733647.1 225853414 7677763 1923852..1924712 1 NC_012441.1 YihY family protein 1924712 yihY 7677763 yihY Brucella melitensis ATCC 23457 YihY family protein YP_002733647.1 1923852 D 546272 CDS YP_002733648.1 225853415 7677764 1924730..1925215 1 NC_012441.1 hypothetical protein 1925215 7677764 BMEA_A2036 Brucella melitensis ATCC 23457 hypothetical protein YP_002733648.1 1924730 D 546272 CDS YP_002733649.1 225853416 7677765 complement(1925223..1925939) 1 NC_012441.1 redoxin domain-containing protein 1925939 7677765 BMEA_A2037 Brucella melitensis ATCC 23457 redoxin domain-containing protein YP_002733649.1 1925223 R 546272 CDS YP_002733650.1 225853417 7677766 1925993..1927393 1 NC_012441.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1927393 argH 7677766 argH Brucella melitensis ATCC 23457 argininosuccinate lyase YP_002733650.1 1925993 D 546272 CDS YP_002733651.1 225853418 7677767 1927498..1927686 1 NC_012441.1 hypothetical protein 1927686 7677767 BMEA_A2039 Brucella melitensis ATCC 23457 hypothetical protein YP_002733651.1 1927498 D 546272 CDS YP_002733652.1 225853419 7677768 1927714..1928979 1 NC_012441.1 diaminopimelate decarboxylase 1928979 lysA 7677768 lysA Brucella melitensis ATCC 23457 diaminopimelate decarboxylase YP_002733652.1 1927714 D 546272 CDS YP_002733653.1 225853420 7677769 1929078..1931723 1 NC_012441.1 hypothetical protein 1931723 7677769 BMEA_A2041 Brucella melitensis ATCC 23457 hypothetical protein YP_002733653.1 1929078 D 546272 CDS YP_002733654.1 225853421 7677770 complement(1931763..1932299) 1 NC_012441.1 hypoxanthine phosphoribosyltransferase 1932299 hpt 7677770 hpt Brucella melitensis ATCC 23457 hypoxanthine phosphoribosyltransferase YP_002733654.1 1931763 R 546272 CDS YP_002733655.1 225853422 7677771 1932448..1933227 1 NC_012441.1 methyltransferase domain-containing protein 1933227 7677771 BMEA_A2043 Brucella melitensis ATCC 23457 methyltransferase domain-containing protein YP_002733655.1 1932448 D 546272 CDS YP_002733656.1 225853423 7677772 1933372..1934478 1 NC_012441.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1934478 hisC 7677772 hisC Brucella melitensis ATCC 23457 histidinol-phosphate aminotransferase YP_002733656.1 1933372 D 546272 CDS YP_002733657.1 225853424 7677773 1934483..1935448 1 NC_012441.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1935448 7677773 BMEA_A2045 Brucella melitensis ATCC 23457 cyclohexadienyl dehydrogenase YP_002733657.1 1934483 D 546272 CDS YP_002733658.1 225853425 7677774 complement(1936456..1936659) 1 NC_012441.1 hypothetical protein 1936659 7677774 BMEA_A2047 Brucella melitensis ATCC 23457 hypothetical protein YP_002733658.1 1936456 R 546272 CDS YP_002733659.1 225853426 7677775 1936648..1937208 1 NC_012441.1 ChaC family protein 1937208 7677775 BMEA_A2048 Brucella melitensis ATCC 23457 ChaC family protein YP_002733659.1 1936648 D 546272 CDS YP_002733660.1 225853427 7677777 complement(1937370..1937486) 1 NC_012441.1 hypothetical protein 1937486 7677777 BMEA_A2050 Brucella melitensis ATCC 23457 hypothetical protein YP_002733660.1 1937370 R 546272 CDS YP_002733661.1 225853428 7677778 1937541..1937831 1 NC_012441.1 hypothetical protein 1937831 7677778 BMEA_A2051 Brucella melitensis ATCC 23457 hypothetical protein YP_002733661.1 1937541 D 546272 CDS YP_002733662.1 225853429 7677779 complement(1938002..1938532) 1 NC_012441.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 1938532 7677779 BMEA_A2052 Brucella melitensis ATCC 23457 inorganic pyrophosphatase YP_002733662.1 1938002 R 546272 CDS YP_002733663.1 225853430 7677780 complement(1938685..1939467) 1 NC_012441.1 phospholipid/glycerol acyltransferase 1939467 7677780 BMEA_A2053 Brucella melitensis ATCC 23457 phospholipid/glycerol acyltransferase YP_002733663.1 1938685 R 546272 CDS YP_002733664.1 225853431 7677781 complement(1939646..1940179) 1 NC_012441.1 hypothetical protein 1940179 7677781 BMEA_A2054 Brucella melitensis ATCC 23457 hypothetical protein YP_002733664.1 1939646 R 546272 CDS YP_002733665.1 225853432 7677782 complement(1940545..1941546) 1 NC_012441.1 hypothetical protein 1941546 7677782 BMEA_A2055 Brucella melitensis ATCC 23457 hypothetical protein YP_002733665.1 1940545 R 546272 CDS YP_002733666.1 225853433 7677783 complement(1941539..1942198) 1 NC_012441.1 cell division ATP-binding protein FtsE 1942198 ftsE 7677783 ftsE Brucella melitensis ATCC 23457 cell division ATP-binding protein FtsE YP_002733666.1 1941539 R 546272 CDS YP_002733667.1 225853434 7677784 complement(1942203..1942379) 1 NC_012441.1 hypothetical protein 1942379 7677784 BMEA_A2057 Brucella melitensis ATCC 23457 hypothetical protein YP_002733667.1 1942203 R 546272 CDS YP_002733668.1 225853435 7677785 complement(1942507..1942779) 1 NC_012441.1 hypothetical protein 1942779 7677785 BMEA_A2058 Brucella melitensis ATCC 23457 hypothetical protein YP_002733668.1 1942507 R 546272 CDS YP_002733669.1 225853436 7677786 1942556..1942873 1 NC_012441.1 hypothetical protein 1942873 7677786 BMEA_A2059 Brucella melitensis ATCC 23457 hypothetical protein YP_002733669.1 1942556 D 546272 CDS YP_002733670.1 225853437 7677787 1943257..1943943 1 NC_012441.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1943943 7677787 BMEA_A2060 Brucella melitensis ATCC 23457 aquaporin Z YP_002733670.1 1943257 D 546272 CDS YP_002733671.1 225853438 7677788 1944324..1945019 1 NC_012441.1 outer membrane lipoprotein carrier protein LolA 1945019 7677788 BMEA_A2061 Brucella melitensis ATCC 23457 outer membrane lipoprotein carrier protein LolA YP_002733671.1 1944324 D 546272 CDS YP_002733672.1 225853439 7677789 1945122..1945928 1 NC_012441.1 exodeoxyribonuclease III 1945928 7677789 BMEA_A2062 Brucella melitensis ATCC 23457 exodeoxyribonuclease III YP_002733672.1 1945122 D 546272 CDS YP_002733673.1 225853440 7677790 complement(1945934..1946395) 1 NC_012441.1 lysophospholipase nte-1 1946395 7677790 BMEA_A2063 Brucella melitensis ATCC 23457 lysophospholipase nte-1 YP_002733673.1 1945934 R 546272 CDS YP_002733674.1 225853441 7677791 complement(1946430..1947113) 1 NC_012441.1 transcriptional regulator BasR/PmrA 1947113 7677791 BMEA_A2064 Brucella melitensis ATCC 23457 transcriptional regulator BasR/PmrA YP_002733674.1 1946430 R 546272 CDS YP_002733675.1 225853442 7677792 1947321..1947866 1 NC_012441.1 hypothetical protein 1947866 7677792 BMEA_A2066 Brucella melitensis ATCC 23457 hypothetical protein YP_002733675.1 1947321 D 546272 CDS YP_002733676.1 225853443 7677793 1947927..1948226 1 NC_012441.1 hypothetical protein 1948226 7677793 BMEA_A2067 Brucella melitensis ATCC 23457 hypothetical protein YP_002733676.1 1947927 D 546272 CDS YP_002733677.1 225853444 7677794 complement(1948255..1949403) 1 NC_012441.1 sulfated surface glycoprotein 185 precursor 1949403 7677794 BMEA_A2069 Brucella melitensis ATCC 23457 sulfated surface glycoprotein 185 precursor YP_002733677.1 1948255 R 546272 CDS YP_002733678.1 225853445 7677795 complement(1949774..1950853) 1 NC_012441.1 hypothetical protein 1950853 7677795 BMEA_A2070 Brucella melitensis ATCC 23457 hypothetical protein YP_002733678.1 1949774 R 546272 CDS YP_002733679.1 225853446 7677796 1951180..1951569 1 NC_012441.1 hypothetical protein 1951569 7677796 BMEA_A2071 Brucella melitensis ATCC 23457 hypothetical protein YP_002733679.1 1951180 D 546272 CDS YP_002733680.1 225853447 7677797 complement(1951656..1953212) 1 NC_012441.1 glycoprotein X 1953212 7677797 BMEA_A2072 Brucella melitensis ATCC 23457 glycoprotein X YP_002733680.1 1951656 R 546272 CDS YP_002733681.1 225853448 7677799 complement(1958313..1958984) 1 NC_012441.1 hypothetical protein 1958984 7677799 BMEA_A2074 Brucella melitensis ATCC 23457 hypothetical protein YP_002733681.1 1958313 R 546272 CDS YP_002733682.1 225853449 7677800 complement(1959064..1959357) 1 NC_012441.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1959357 rpmB 7677800 rpmB Brucella melitensis ATCC 23457 50S ribosomal protein L28 YP_002733682.1 1959064 R 546272 CDS YP_002733683.1 225853450 7677801 1959719..1960534 1 NC_012441.1 hypothetical protein 1960534 7677801 BMEA_A2076 Brucella melitensis ATCC 23457 hypothetical protein YP_002733683.1 1959719 D 546272 CDS YP_002733684.1 225853451 7676365 complement(1960646..1961068) 1 NC_012441.1 MerR family transcriptional regulator 1961068 7676365 BMEA_A2077 Brucella melitensis ATCC 23457 MerR family transcriptional regulator YP_002733684.1 1960646 R 546272 CDS YP_002733685.1 225853452 7678045 1961157..1963571 1 NC_012441.1 heavy metal translocating P-type ATPase 1963571 7678045 BMEA_A2078 Brucella melitensis ATCC 23457 heavy metal translocating P-type ATPase YP_002733685.1 1961157 D 546272 CDS YP_002733686.1 225853453 7678046 1963978..1964727 1 NC_012441.1 hypothetical protein 1964727 7678046 BMEA_A2079 Brucella melitensis ATCC 23457 hypothetical protein YP_002733686.1 1963978 D 546272 CDS YP_002733687.1 225853454 7678047 1964754..1965839 1 NC_012441.1 hypothetical protein 1965839 7678047 BMEA_A2080 Brucella melitensis ATCC 23457 hypothetical protein YP_002733687.1 1964754 D 546272 CDS YP_002733688.1 225853455 7678048 complement(1966012..1967913) 1 NC_012441.1 cobaltochelatase subunit CobT 1967913 7678048 BMEA_A2081 Brucella melitensis ATCC 23457 cobaltochelatase subunit CobT YP_002733688.1 1966012 R 546272 CDS YP_002733689.1 225853456 7678049 complement(1968021..1969007) 1 NC_012441.1 cobaltochelatase subunit CobS 1969007 7678049 BMEA_A2082 Brucella melitensis ATCC 23457 cobaltochelatase subunit CobS YP_002733689.1 1968021 R 546272 CDS YP_002733690.1 225853457 7678050 1969086..1969316 1 NC_012441.1 hypothetical protein 1969316 7678050 BMEA_A2083 Brucella melitensis ATCC 23457 hypothetical protein YP_002733690.1 1969086 D 546272 CDS YP_002733691.1 225853458 7678051 complement(1969294..1969923) 1 NC_012441.1 DnaJ domain-containing protein 1969923 7678051 BMEA_A2084 Brucella melitensis ATCC 23457 DnaJ domain-containing protein YP_002733691.1 1969294 R 546272 CDS YP_002733692.1 225853459 7678052 complement(1969920..1970117) 1 NC_012441.1 hypothetical protein 1970117 7678052 BMEA_A2085 Brucella melitensis ATCC 23457 hypothetical protein YP_002733692.1 1969920 R 546272 CDS YP_002733693.1 225853460 7678053 1970110..1970424 1 NC_012441.1 BolA protein 1970424 7678053 BMEA_A2086 Brucella melitensis ATCC 23457 BolA protein YP_002733693.1 1970110 D 546272 CDS YP_002733694.1 225853461 7678054 complement(1970449..1971756) 1 NC_012441.1 hypothetical protein 1971756 7678054 BMEA_A2087 Brucella melitensis ATCC 23457 hypothetical protein YP_002733694.1 1970449 R 546272 CDS YP_002733695.1 225853462 7678055 complement(1971820..1972956) 1 NC_012441.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1972956 aroB 7678055 aroB Brucella melitensis ATCC 23457 3-dehydroquinate synthase YP_002733695.1 1971820 R 546272 CDS YP_002733696.1 225853463 7678056 complement(1973049..1973651) 1 NC_012441.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1973651 7678056 BMEA_A2089 Brucella melitensis ATCC 23457 shikimate kinase YP_002733696.1 1973049 R 546272 CDS YP_002733697.1 225853464 7678057 1973797..1973982 1 NC_012441.1 hypothetical protein 1973982 7678057 BMEA_A2090 Brucella melitensis ATCC 23457 hypothetical protein YP_002733697.1 1973797 D 546272 CDS YP_002733698.1 225853465 7678058 1973985..1974908 1 NC_012441.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1974908 xerD 7678058 xerD Brucella melitensis ATCC 23457 site-specific tyrosine recombinase XerD YP_002733698.1 1973985 D 546272 CDS YP_002733699.1 225853466 7678059 1975047..1976000 1 NC_012441.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1976000 accA 7678059 accA Brucella melitensis ATCC 23457 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002733699.1 1975047 D 546272 CDS YP_002733700.1 225853467 7678060 1976222..1977433 1 NC_012441.1 hypothetical protein 1977433 7678060 BMEA_A2093 Brucella melitensis ATCC 23457 hypothetical protein YP_002733700.1 1976222 D 546272 CDS YP_002733701.1 225853468 7678061 1977412..1977669 1 NC_012441.1 SirA family protein 1977669 7678061 BMEA_A2094 Brucella melitensis ATCC 23457 SirA family protein YP_002733701.1 1977412 D 546272 CDS YP_002733702.1 225853469 7678062 complement(1977687..1978859) 1 NC_012441.1 cobalamin synthesis protein P47K 1978859 7678062 BMEA_A2095 Brucella melitensis ATCC 23457 cobalamin synthesis protein P47K YP_002733702.1 1977687 R 546272 CDS YP_002733703.1 225853470 7678063 complement(1978861..1979973) 1 NC_012441.1 serine-type D-Ala-D-Ala carboxypeptidase 1979973 7678063 BMEA_A2096 Brucella melitensis ATCC 23457 serine-type D-Ala-D-Ala carboxypeptidase YP_002733703.1 1978861 R 546272 CDS YP_002733704.1 225853471 7678065 1981431..1981565 1 NC_012441.1 hypothetical protein 1981565 7678065 BMEA_A2098 Brucella melitensis ATCC 23457 hypothetical protein YP_002733704.1 1981431 D 546272 CDS YP_002733705.1 225853472 7678067 complement(1981633..1982397) 1 NC_012441.1 glucose 1-dehydrogenase 1982397 7678067 BMEA_A2100 Brucella melitensis ATCC 23457 glucose 1-dehydrogenase YP_002733705.1 1981633 R 546272 CDS YP_002733706.1 225853473 7678069 1983037..1983432 1 NC_012441.1 hypothetical protein 1983432 7678069 BMEA_A2102 Brucella melitensis ATCC 23457 hypothetical protein YP_002733706.1 1983037 D 546272 CDS YP_002733707.1 225853474 7678071 complement(1985134..1985898) 1 NC_012441.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1985898 7678071 BMEA_A2104 Brucella melitensis ATCC 23457 3-ketoacyl-ACP reductase YP_002733707.1 1985134 R 546272 CDS YP_002733708.1 225853475 7678072 complement(1985895..1987379) 1 NC_012441.1 glucose-methanol-choline oxidoreductase 1987379 7678072 BMEA_A2105 Brucella melitensis ATCC 23457 glucose-methanol-choline oxidoreductase YP_002733708.1 1985895 R 546272 CDS YP_002733709.1 225853476 7678073 complement(1987392..1988912) 1 NC_012441.1 aldehyde dehydrogenase 1988912 7678073 BMEA_A2106 Brucella melitensis ATCC 23457 aldehyde dehydrogenase YP_002733709.1 1987392 R 546272 CDS YP_002733710.1 225853477 7678074 complement(1988906..1989682) 1 NC_012441.1 enoyl-CoA hydratase/isomerase 1989682 7678074 BMEA_A2107 Brucella melitensis ATCC 23457 enoyl-CoA hydratase/isomerase YP_002733710.1 1988906 R 546272 CDS YP_002733711.1 225853478 7678075 complement(1989684..1991174) 1 NC_012441.1 coenzyme A transferase 1991174 7678075 BMEA_A2108 Brucella melitensis ATCC 23457 coenzyme A transferase YP_002733711.1 1989684 R 546272 CDS YP_002733712.1 225853479 7678076 complement(1991180..1992181) 1 NC_012441.1 hypothetical protein 1992181 7678076 BMEA_A2109 Brucella melitensis ATCC 23457 hypothetical protein YP_002733712.1 1991180 R 546272 CDS YP_002733713.1 225853480 7678077 complement(1992160..1993218) 1 NC_012441.1 alanine racemase 1993218 7678077 BMEA_A2110 Brucella melitensis ATCC 23457 alanine racemase YP_002733713.1 1992160 R 546272 CDS YP_002733714.1 225853481 7678078 1993469..1994638 1 NC_012441.1 hypothetical protein 1994638 7678078 BMEA_A2111 Brucella melitensis ATCC 23457 hypothetical protein YP_002733714.1 1993469 D 546272 CDS YP_002733715.1 225853482 7678079 complement(1994672..1995694) 1 NC_012441.1 alkanal monooxygenase subunit alpha 1995694 7678079 BMEA_A2112 Brucella melitensis ATCC 23457 alkanal monooxygenase subunit alpha YP_002733715.1 1994672 R 546272 CDS YP_002733716.1 225853483 7678080 complement(1995691..1995900) 1 NC_012441.1 hypothetical protein 1995900 7678080 BMEA_A2113 Brucella melitensis ATCC 23457 hypothetical protein YP_002733716.1 1995691 R 546272 CDS YP_002733717.1 225853484 7678081 1995963..1996928 1 NC_012441.1 hypothetical protein 1996928 7678081 BMEA_A2114 Brucella melitensis ATCC 23457 hypothetical protein YP_002733717.1 1995963 D 546272 CDS YP_002733718.1 225853485 7678082 complement(1997436..1997570) 1 NC_012441.1 hypothetical protein 1997570 7678082 BMEA_A2115 Brucella melitensis ATCC 23457 hypothetical protein YP_002733718.1 1997436 R 546272 CDS YP_002733719.1 225853486 7678083 1997572..1998456 1 NC_012441.1 hypothetical protein 1998456 7678083 BMEA_A2116 Brucella melitensis ATCC 23457 hypothetical protein YP_002733719.1 1997572 D 546272 CDS YP_002733720.1 225853487 7678084 1998453..1999247 1 NC_012441.1 ABC transporter 1999247 7678084 BMEA_A2117 Brucella melitensis ATCC 23457 ABC transporter YP_002733720.1 1998453 D 546272 CDS YP_002733721.1 225853488 7678085 1999409..2000452 1 NC_012441.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 2000452 holA 7678085 holA Brucella melitensis ATCC 23457 DNA polymerase III subunit delta YP_002733721.1 1999409 D 546272 CDS YP_002733722.1 225853489 7678086 complement(2000546..2001427) 1 NC_012441.1 ParB-like partition protein 2001427 7678086 BMEA_A2119 Brucella melitensis ATCC 23457 ParB-like partition protein YP_002733722.1 2000546 R 546272 CDS YP_002733723.1 225853490 7678087 complement(2001471..2002268) 1 NC_012441.1 hypothetical protein 2002268 7678087 BMEA_A2120 Brucella melitensis ATCC 23457 hypothetical protein YP_002733723.1 2001471 R 546272 CDS YP_002733724.1 225853491 7678088 complement(2002321..2002962) 1 NC_012441.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2002962 gidB 7678088 gidB Brucella melitensis ATCC 23457 16S rRNA methyltransferase GidB YP_002733724.1 2002321 R 546272 CDS YP_002733725.1 225853492 7678089 complement(2002959..2004869) 1 NC_012441.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2004869 gidA 7678089 gidA Brucella melitensis ATCC 23457 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002733725.1 2002959 R 546272 CDS YP_002733726.1 225853493 7678090 complement(2005096..2006424) 1 NC_012441.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2006424 trmE 7678090 trmE Brucella melitensis ATCC 23457 tRNA modification GTPase TrmE YP_002733726.1 2005096 R 546272 CDS YP_002733727.1 225853494 7678092 complement(2008553..2009818) 1 NC_012441.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 2009818 rho 7678092 rho Brucella melitensis ATCC 23457 transcription termination factor Rho YP_002733727.1 2008553 R 546272 CDS YP_002733728.1 225853495 7678093 complement(2010200..2010736) 1 NC_012441.1 hypothetical protein 2010736 7678093 BMEA_A2126 Brucella melitensis ATCC 23457 hypothetical protein YP_002733728.1 2010200 R 546272 CDS YP_002733729.1 225853496 7678094 complement(2010733..2011758) 1 NC_012441.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 2011758 hemE 7678094 hemE Brucella melitensis ATCC 23457 uroporphyrinogen decarboxylase YP_002733729.1 2010733 R 546272 CDS YP_002733730.1 225853497 7678095 complement(2011991..2012104) 1 NC_012441.1 hypothetical protein 2012104 7678095 BMEA_A2128 Brucella melitensis ATCC 23457 hypothetical protein YP_002733730.1 2011991 R 546272 CDS YP_002733731.1 225853498 7678096 2012211..2013050 1 NC_012441.1 hypothetical protein 2013050 7678096 BMEA_A2129 Brucella melitensis ATCC 23457 hypothetical protein YP_002733731.1 2012211 D 546272 CDS YP_002733732.1 225853499 7678097 2013047..2013646 1 NC_012441.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2013646 maf 7678097 maf Brucella melitensis ATCC 23457 Maf-like protein YP_002733732.1 2013047 D 546272 CDS YP_002733733.1 225853500 7678098 2013639..2014508 1 NC_012441.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 2014508 aroE 7678098 aroE Brucella melitensis ATCC 23457 shikimate 5-dehydrogenase YP_002733733.1 2013639 D 546272 CDS YP_002733734.1 225853501 7678099 2014505..2015107 1 NC_012441.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2015107 coaE 7678099 coaE Brucella melitensis ATCC 23457 dephospho-CoA kinase YP_002733734.1 2014505 D 546272 CDS YP_002733735.1 225853502 7678100 2015149..2015853 1 NC_012441.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 2015853 dnaQ 7678100 dnaQ Brucella melitensis ATCC 23457 DNA polymerase III subunit epsilon YP_002733735.1 2015149 D 546272 CDS YP_002733736.1 225853503 7678101 complement(2015912..2016403) 1 NC_012441.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 2016403 secB 7678101 secB Brucella melitensis ATCC 23457 preprotein translocase subunit SecB YP_002733736.1 2015912 R 546272 CDS YP_002733737.1 225853504 7678102 complement(2016523..2017020) 1 NC_012441.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 2017020 7678102 BMEA_A2135 Brucella melitensis ATCC 23457 FxsA protein YP_002733737.1 2016523 R 546272 CDS YP_002733738.1 225853505 7678103 2017237..2017932 1 NC_012441.1 import inner membrane translocase subunit Tim44 2017932 7678103 BMEA_A2136 Brucella melitensis ATCC 23457 import inner membrane translocase subunit Tim44 YP_002733738.1 2017237 D 546272 CDS YP_002733739.1 225853506 7678104 2017996..2019105 1 NC_012441.1 MltA domain-containing protein 2019105 7678104 BMEA_A2137 Brucella melitensis ATCC 23457 MltA domain-containing protein YP_002733739.1 2017996 D 546272 CDS YP_002733740.1 225853507 7678105 2019111..2019713 1 NC_012441.1 Smr protein/MutS2 2019713 7678105 BMEA_A2138 Brucella melitensis ATCC 23457 Smr protein/MutS2 YP_002733740.1 2019111 D 546272 CDS YP_002733741.1 225853508 7678106 2019710..2020090 1 NC_012441.1 XRE family transcriptional regulator 2020090 7678106 BMEA_A2139 Brucella melitensis ATCC 23457 XRE family transcriptional regulator YP_002733741.1 2019710 D 546272 CDS YP_002733742.1 225853509 7678107 complement(2020099..2021118) 1 NC_012441.1 hypothetical protein 2021118 7678107 BMEA_A2140 Brucella melitensis ATCC 23457 hypothetical protein YP_002733742.1 2020099 R 546272 CDS YP_002733743.1 225853510 7678108 complement(2021265..2022569) 1 NC_012441.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 2022569 hslU 7678108 hslU Brucella melitensis ATCC 23457 ATP-dependent protease ATP-binding subunit HslU YP_002733743.1 2021265 R 546272 CDS YP_002733744.1 225853511 7678109 complement(2022643..2023197) 1 NC_012441.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 2023197 7678109 BMEA_A2142 Brucella melitensis ATCC 23457 ATP-dependent protease peptidase subunit YP_002733744.1 2022643 R 546272 CDS YP_002733745.1 225853512 7678110 2023494..2024102 1 NC_012441.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2024102 7678110 BMEA_A2143 Brucella melitensis ATCC 23457 imidazoleglycerol-phosphate dehydratase YP_002733745.1 2023494 D 546272 CDS YP_002733746.1 225853513 7678111 2024214..2024723 1 NC_012441.1 hypothetical protein 2024723 7678111 BMEA_A2144 Brucella melitensis ATCC 23457 hypothetical protein YP_002733746.1 2024214 D 546272 CDS YP_002733747.1 225853514 7678112 2024726..2025376 1 NC_012441.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2025376 hisH 7678112 hisH Brucella melitensis ATCC 23457 imidazole glycerol phosphate synthase subunit HisH YP_002733747.1 2024726 D 546272 CDS YP_002733748.1 225853515 7678113 2025381..2026112 1 NC_012441.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2026112 hisA 7678113 hisA Brucella melitensis ATCC 23457 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002733748.1 2025381 D 546272 CDS YP_002733749.1 225853516 7678114 2026109..2026894 1 NC_012441.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2026894 hisF 7678114 hisF Brucella melitensis ATCC 23457 imidazole glycerol phosphate synthase subunit HisF YP_002733749.1 2026109 D 546272 CDS YP_002733750.1 225853517 7678115 2027030..2027353 1 NC_012441.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2027353 hisE 7678115 hisE Brucella melitensis ATCC 23457 phosphoribosyl-ATP pyrophosphatase YP_002733750.1 2027030 D 546272 CDS YP_002733751.1 225853518 7678116 2027368..2028336 1 NC_012441.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2028336 coaA 7678116 coaA Brucella melitensis ATCC 23457 pantothenate kinase YP_002733751.1 2027368 D 546272 CDS YP_002733752.1 225853519 7678117 complement(2028399..2028836) 1 NC_012441.1 peptidyl-tRNA hydrolase domain-containing protein 2028836 7678117 BMEA_A2150 Brucella melitensis ATCC 23457 peptidyl-tRNA hydrolase domain-containing protein YP_002733752.1 2028399 R 546272 CDS YP_002733753.1 225853520 7678119 2030959..2031678 1 NC_012441.1 transcriptional regulator ChvI 2031678 7678119 BMEA_A2153 Brucella melitensis ATCC 23457 transcriptional regulator ChvI YP_002733753.1 2030959 D 546272 CDS YP_002733754.1 225853521 7678120 2031789..2033594 1 NC_012441.1 sensor protein chvG 2033594 7678120 BMEA_A2154 Brucella melitensis ATCC 23457 sensor protein chvG YP_002733754.1 2031789 D 546272 CDS YP_002733755.1 225853522 7678121 2033620..2034099 1 NC_012441.1 HPr kinase 2034099 7678121 BMEA_A2155 Brucella melitensis ATCC 23457 HPr kinase YP_002733755.1 2033620 D 546272 CDS YP_002733756.1 225853523 7678122 2034351..2034752 1 NC_012441.1 PTS system fructose subfamily transporter subunit IIA 2034752 7678122 BMEA_A2156 Brucella melitensis ATCC 23457 PTS system fructose subfamily transporter subunit IIA YP_002733756.1 2034351 D 546272 CDS YP_002733757.1 225853524 7678123 2034756..2035070 1 NC_012441.1 HPr family phosphocarrier 2035070 7678123 BMEA_A2157 Brucella melitensis ATCC 23457 HPr family phosphocarrier YP_002733757.1 2034756 D 546272 CDS YP_002733758.1 225853525 7678124 2035134..2035451 1 NC_012441.1 hypothetical protein 2035451 7678124 BMEA_A2158 Brucella melitensis ATCC 23457 hypothetical protein YP_002733758.1 2035134 D 546272 CDS YP_002733759.1 225853526 7678125 2035448..2036848 1 NC_012441.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2036848 ahcY 7678125 ahcY Brucella melitensis ATCC 23457 S-adenosyl-L-homocysteine hydrolase YP_002733759.1 2035448 D 546272 CDS YP_002733760.1 225853527 7678126 2037233..2039812 1 NC_012441.1 histidine kinase 2039812 7678126 BMEA_A2160 Brucella melitensis ATCC 23457 histidine kinase YP_002733760.1 2037233 D 546272 CDS YP_002733761.1 225853528 7678127 2039821..2041362 1 NC_012441.1 hypothetical protein 2041362 7678127 BMEA_A2161 Brucella melitensis ATCC 23457 hypothetical protein YP_002733761.1 2039821 D 546272 CDS YP_002733762.1 225853529 7678128 2041349..2042068 1 NC_012441.1 nucleotidyl transferase 2042068 7678128 BMEA_A2162 Brucella melitensis ATCC 23457 nucleotidyl transferase YP_002733762.1 2041349 D 546272 CDS YP_002733763.1 225853530 7678129 2042083..2045241 1 NC_012441.1 double-strand break repair protein AddB 2045241 addB 7678129 addB Brucella melitensis ATCC 23457 double-strand break repair protein AddB YP_002733763.1 2042083 D 546272 CDS YP_002733764.1 225853531 7678130 2045238..2048780 1 NC_012441.1 double-strand break repair helicase AddA 2048780 addA 7678130 addA Brucella melitensis ATCC 23457 double-strand break repair helicase AddA YP_002733764.1 2045238 D 546272 CDS YP_002733765.1 225853532 7678131 2048962..2049285 1 NC_012441.1 thioredoxin 2049285 trx 7678131 trx Brucella melitensis ATCC 23457 thioredoxin YP_002733765.1 2048962 D 546272 CDS YP_002733766.1 225853533 7678132 complement(2049499..2050827) 1 NC_012441.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC 2050827 folC 7678132 folC Brucella melitensis ATCC 23457 bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC YP_002733766.1 2049499 R 546272 CDS YP_002733767.1 225853534 7678133 complement(2050830..2051735) 1 NC_012441.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2051735 accD 7678133 accD Brucella melitensis ATCC 23457 acetyl-CoA carboxylase subunit beta YP_002733767.1 2050830 R 546272 CDS YP_002733768.1 225853535 7678134 complement(2051796..2052635) 1 NC_012441.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2052635 trpA 7678134 trpA Brucella melitensis ATCC 23457 tryptophan synthase subunit alpha YP_002733768.1 2051796 R 546272 CDS YP_002733769.1 225853536 7678135 complement(2052632..2053099) 1 NC_012441.1 hypothetical protein 2053099 7678135 BMEA_A2169 Brucella melitensis ATCC 23457 hypothetical protein YP_002733769.1 2052632 R 546272 CDS YP_002733770.1 225853537 7678136 complement(2053102..2054322) 1 NC_012441.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2054322 trpB 7678136 trpB Brucella melitensis ATCC 23457 tryptophan synthase subunit beta YP_002733770.1 2053102 R 546272 CDS YP_002733771.1 225853538 7678137 complement(2054342..2055010) 1 NC_012441.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 2055010 7678137 BMEA_A2171 Brucella melitensis ATCC 23457 N-(5'-phosphoribosyl)anthranilate isomerase YP_002733771.1 2054342 R 546272 CDS YP_002733772.1 225853539 7678138 complement(2055049..2055684) 1 NC_012441.1 hypothetical protein 2055684 7678138 BMEA_A2172 Brucella melitensis ATCC 23457 hypothetical protein YP_002733772.1 2055049 R 546272 CDS YP_002733773.1 225853540 7678139 complement(2055681..2056442) 1 NC_012441.1 hypothetical protein 2056442 7678139 BMEA_A2173 Brucella melitensis ATCC 23457 hypothetical protein YP_002733773.1 2055681 R 546272 CDS YP_002733774.1 225853541 7678140 complement(2056551..2056913) 1 NC_012441.1 hypothetical protein 2056913 7678140 BMEA_A2174 Brucella melitensis ATCC 23457 hypothetical protein YP_002733774.1 2056551 R 546272 CDS YP_002733775.1 225853542 7678141 complement(2057180..2058331) 1 NC_012441.1 benzoate transporter 2058331 7678141 BMEA_A2175 Brucella melitensis ATCC 23457 benzoate transporter YP_002733775.1 2057180 R 546272 CDS YP_002733776.1 225853543 7678142 complement(2058345..2059136) 1 NC_012441.1 hypothetical protein 2059136 7678142 BMEA_A2176 Brucella melitensis ATCC 23457 hypothetical protein YP_002733776.1 2058345 R 546272 CDS YP_002733777.1 225853544 7678143 2059568..2059972 1 NC_012441.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2059972 7678143 BMEA_A2177 Brucella melitensis ATCC 23457 translation initiation factor IF-3 YP_002733777.1 2059568 D 546272 CDS YP_002733778.1 225853545 7678144 2060101..2060715 1 NC_012441.1 nickel-cobalt-cadmium resistance protein NccN 2060715 7678144 BMEA_A2178 Brucella melitensis ATCC 23457 nickel-cobalt-cadmium resistance protein NccN YP_002733778.1 2060101 D 546272 CDS YP_002733779.1 225853546 7678145 2060982..2061182 1 NC_012441.1 50S ribosomal protein L35 2061182 rpmI 7678145 rpmI Brucella melitensis ATCC 23457 50S ribosomal protein L35 YP_002733779.1 2060982 D 546272 CDS YP_002733780.1 225853547 7676664 2061210..2061614 1 NC_012441.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2061614 rplT 7676664 rplT Brucella melitensis ATCC 23457 50S ribosomal protein L20 YP_002733780.1 2061210 D 546272 CDS YP_002733781.1 225853548 7676665 2061713..2062555 1 NC_012441.1 hypothetical protein 2062555 7676665 BMEA_A2181 Brucella melitensis ATCC 23457 hypothetical protein YP_002733781.1 2061713 D 546272 CDS YP_002733782.1 225853549 7676666 2062643..2063752 1 NC_012441.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2063752 pheS 7676666 pheS Brucella melitensis ATCC 23457 phenylalanyl-tRNA synthetase subunit alpha YP_002733782.1 2062643 D 546272 CDS YP_002733783.1 225853550 7676667 2063774..2066188 1 NC_012441.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2066188 pheT 7676667 pheT Brucella melitensis ATCC 23457 phenylalanyl-tRNA synthetase subunit beta YP_002733783.1 2063774 D 546272 CDS YP_002733784.1 225853551 7676668 2066258..2067244 1 NC_012441.1 oxidoreductase 2067244 7676668 BMEA_A2184 Brucella melitensis ATCC 23457 oxidoreductase YP_002733784.1 2066258 D 546272 CDS YP_002733785.1 225853552 7676669 2067470..2069383 1 NC_012441.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2069383 dnaK 7676669 dnaK Brucella melitensis ATCC 23457 molecular chaperone DnaK YP_002733785.1 2067470 D 546272 CDS YP_002733786.1 225853553 7676670 complement(2069401..2069595) 1 NC_012441.1 hypothetical protein 2069595 7676670 BMEA_A2187 Brucella melitensis ATCC 23457 hypothetical protein YP_002733786.1 2069401 R 546272 CDS YP_002733787.1 225853554 7676671 2069629..2070762 1 NC_012441.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2070762 dnaJ 7676671 dnaJ Brucella melitensis ATCC 23457 chaperone protein DnaJ YP_002733787.1 2069629 D 546272 CDS YP_002733788.1 225853555 7676672 2070883..2071482 1 NC_012441.1 phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamine N-methyltransferase 2071482 7676672 BMEA_A2189 Brucella melitensis ATCC 23457 phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamine N-methyltransferase YP_002733788.1 2070883 D 546272 CDS YP_002733789.1 225853556 7676673 2071692..2072408 1 NC_012441.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2072408 pyrF 7676673 pyrF Brucella melitensis ATCC 23457 orotidine 5'-phosphate decarboxylase YP_002733789.1 2071692 D 546272 CDS YP_002733790.1 225853557 7676674 2072457..2072744 1 NC_012441.1 hypothetical protein 2072744 7676674 BMEA_A2191 Brucella melitensis ATCC 23457 hypothetical protein YP_002733790.1 2072457 D 546272 CDS YP_002733791.1 225853558 7676675 complement(2072782..2073969) 1 NC_012441.1 regucalcin 2073969 7676675 BMEA_A2192 Brucella melitensis ATCC 23457 regucalcin YP_002733791.1 2072782 R 546272 CDS YP_002733792.1 225853559 7676676 2073905..2074843 1 NC_012441.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2074843 gshB 7676676 gshB Brucella melitensis ATCC 23457 glutathione synthetase YP_002733792.1 2073905 D 546272 CDS YP_002733793.1 225853560 7676677 2074929..2076485 1 NC_012441.1 Mg chelatase-like protein 2076485 7676677 BMEA_A2194 Brucella melitensis ATCC 23457 Mg chelatase-like protein YP_002733793.1 2074929 D 546272 CDS YP_002733794.1 225853561 7676678 complement(2076534..2077154) 1 NC_012441.1 transglutaminase 2077154 7676678 BMEA_A2195 Brucella melitensis ATCC 23457 transglutaminase YP_002733794.1 2076534 R 546272 CDS YP_002733795.1 225853562 7676679 complement(2077602..2077958) 1 NC_012441.1 rare lipoprotein A 2077958 rlpA 7676679 rlpA Brucella melitensis ATCC 23457 rare lipoprotein A YP_002733795.1 2077602 R 546272 CDS YP_002733796.1 225853563 7676680 2078117..2078335 1 NC_012441.1 hypothetical protein 2078335 7676680 BMEA_A2197 Brucella melitensis ATCC 23457 hypothetical protein YP_002733796.1 2078117 D 546272 CDS YP_002733797.1 225853564 7676681 2078568..2078918 1 NC_012441.1 hypothetical protein 2078918 7676681 BMEA_A2198 Brucella melitensis ATCC 23457 hypothetical protein YP_002733797.1 2078568 D 546272 CDS YP_002733798.1 225853565 7676682 2079073..2080119 1 NC_012441.1 hypothetical protein 2080119 7676682 BMEA_A2199 Brucella melitensis ATCC 23457 hypothetical protein YP_002733798.1 2079073 D 546272 CDS YP_002733799.1 225853566 7676683 2080261..2081751 1 NC_012441.1 phosphate ABC transporter permease 2081751 pstC 7676683 pstC Brucella melitensis ATCC 23457 phosphate ABC transporter permease YP_002733799.1 2080261 D 546272 CDS YP_002733800.1 225853567 7676684 2081751..2083061 1 NC_012441.1 phosphate ABC transporter permease 2083061 pstA 7676684 pstA Brucella melitensis ATCC 23457 phosphate ABC transporter permease YP_002733800.1 2081751 D 546272 CDS YP_002733801.1 225853568 7676685 2083078..2083899 1 NC_012441.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2083899 pstB 7676685 pstB Brucella melitensis ATCC 23457 phosphate transporter ATP-binding protein YP_002733801.1 2083078 D 546272 CDS YP_002733802.1 225853569 7676686 2083965..2084687 1 NC_012441.1 phosphate transport system regulatory protein PhoU 2084687 phoU 7676686 phoU Brucella melitensis ATCC 23457 phosphate transport system regulatory protein PhoU YP_002733802.1 2083965 D 546272 CDS YP_002733803.1 225853570 7676687 2084805..2085491 1 NC_012441.1 phosphate regulon transcriptional regulatory protein PhoB 2085491 phoB 7676687 phoB Brucella melitensis ATCC 23457 phosphate regulon transcriptional regulatory protein PhoB YP_002733803.1 2084805 D 546272 CDS YP_002733804.1 225853571 7676688 complement(2085847..2086005) 1 NC_012441.1 hypothetical protein 2086005 7676688 BMEA_A2205 Brucella melitensis ATCC 23457 hypothetical protein YP_002733804.1 2085847 R 546272 CDS YP_002733805.1 225853572 7676689 2086077..2087057 1 NC_012441.1 cell wall hydrolase SleB 2087057 7676689 BMEA_A2206 Brucella melitensis ATCC 23457 cell wall hydrolase SleB YP_002733805.1 2086077 D 546272 CDS YP_002733806.1 225853573 7676690 complement(2087167..2087490) 1 NC_012441.1 lipoprotein 2087490 7676690 BMEA_A2207 Brucella melitensis ATCC 23457 lipoprotein YP_002733806.1 2087167 R 546272 CDS YP_002733807.1 225853574 7676691 2087567..2088820 1 NC_012441.1 aminopeptidase T 2088820 7676691 BMEA_A2208 Brucella melitensis ATCC 23457 aminopeptidase T YP_002733807.1 2087567 D 546272 CDS YP_002733808.1 225853575 7676692 complement(2088981..2089478) 1 NC_012441.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 2089478 7676692 BMEA_A2209 Brucella melitensis ATCC 23457 DNA starvation/stationary phase protection protein Dps YP_002733808.1 2088981 R 546272 CDS YP_002733809.1 225853576 7676693 2089761..2090450 1 NC_012441.1 peptidase M22 glycoprotease 2090450 7676693 BMEA_A2210 Brucella melitensis ATCC 23457 peptidase M22 glycoprotease YP_002733809.1 2089761 D 546272 CDS YP_002733810.1 225853577 7676694 2090455..2090955 1 NC_012441.1 ribosomal-protein-alanine acetyltransferase 2090955 7676694 BMEA_A2211 Brucella melitensis ATCC 23457 ribosomal-protein-alanine acetyltransferase YP_002733810.1 2090455 D 546272 CDS YP_002733811.1 225853578 7676695 2090952..2091755 1 NC_012441.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 2091755 7676695 BMEA_A2212 Brucella melitensis ATCC 23457 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002733811.1 2090952 D 546272 CDS YP_002733812.1 225853579 7676696 2091813..2093216 1 NC_012441.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2093216 7676696 BMEA_A2213 Brucella melitensis ATCC 23457 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002733812.1 2091813 D 546272 CDS YP_002733813.1 225853580 7676697 2093453..2094436 1 NC_012441.1 hypothetical protein 2094436 7676697 BMEA_A2214 Brucella melitensis ATCC 23457 hypothetical protein YP_002733813.1 2093453 D 546272 CDS YP_002733814.1 225853581 7676698 2094572..2095078 1 NC_012441.1 hypothetical protein 2095078 7676698 BMEA_A2215 Brucella melitensis ATCC 23457 hypothetical protein YP_002733814.1 2094572 D 546272 CDS YP_002733815.1 225853582 7676699 2095081..2096199 1 NC_012441.1 hemolysin C 2096199 7676699 BMEA_A2216 Brucella melitensis ATCC 23457 hemolysin C YP_002733815.1 2095081 D 546272 CDS YP_002733816.1 225853583 7676700 2096196..2097794 1 NC_012441.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2097794 lnt 7676700 lnt Brucella melitensis ATCC 23457 apolipoprotein N-acyltransferase YP_002733816.1 2096196 D 546272 CDS YP_002733817.1 225853584 7676701 2097941..2098354 1 NC_012441.1 XRE family transcriptional regulator 2098354 7676701 BMEA_A2219 Brucella melitensis ATCC 23457 XRE family transcriptional regulator YP_002733817.1 2097941 D 546272 CDS YP_002733818.1 225853585 7676702 2098581..2099846 1 NC_012441.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2099846 metK 7676702 metK Brucella melitensis ATCC 23457 S-adenosylmethionine synthetase YP_002733818.1 2098581 D 546272 CDS YP_002733819.1 225853586 7676703 2099855..2100556 1 NC_012441.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2100556 7676703 BMEA_A2221 Brucella melitensis ATCC 23457 tRNA (guanine-N(7)-)-methyltransferase YP_002733819.1 2099855 D 546272 CDS YP_002733820.1 225853587 7676704 2100736..2101395 1 NC_012441.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2101395 7676704 BMEA_A2222 Brucella melitensis ATCC 23457 hypothetical protein YP_002733820.1 2100736 D 546272 CDS YP_002733821.1 225853588 7676705 2101448..2103061 1 NC_012441.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2103061 nusA 7676705 nusA Brucella melitensis ATCC 23457 transcription elongation factor NusA YP_002733821.1 2101448 D 546272 CDS YP_002733822.1 225853589 7676706 2103444..2104046 1 NC_012441.1 hypothetical protein 2104046 7676706 BMEA_A2224 Brucella melitensis ATCC 23457 hypothetical protein YP_002733822.1 2103444 D 546272 CDS YP_002733823.1 225853590 7676707 2104184..2107063 1 NC_012441.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2107063 infB 7676707 infB Brucella melitensis ATCC 23457 translation initiation factor IF-2 YP_002733823.1 2104184 D 546272 CDS YP_002733824.1 225853591 7676708 2107329..2107781 1 NC_012441.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2107781 rbfA 7676708 rbfA Brucella melitensis ATCC 23457 ribosome-binding factor A YP_002733824.1 2107329 D 546272 CDS YP_002733825.1 225853592 7676709 2107785..2108759 1 NC_012441.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2108759 truB 7676709 truB Brucella melitensis ATCC 23457 tRNA pseudouridine synthase B YP_002733825.1 2107785 D 546272 CDS YP_002733826.1 225853593 7676710 2108930..2109199 1 NC_012441.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2109199 rpsO 7676710 rpsO Brucella melitensis ATCC 23457 30S ribosomal protein S15 YP_002733826.1 2108930 D 546272 CDS YP_002733827.1 225853594 7676711 2109483..2111627 1 NC_012441.1 polynucleotide phosphorylase/polyadenylase 2111627 7676711 BMEA_A2229 Brucella melitensis ATCC 23457 polynucleotide phosphorylase/polyadenylase YP_002733827.1 2109483 D 546272 CDS YP_002733828.1 225853595 7676713 complement(2112809..2113627) 1 NC_012441.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2113627 7676713 BMEA_A2231 Brucella melitensis ATCC 23457 enoyl-(acyl carrier protein) reductase YP_002733828.1 2112809 R 546272 CDS YP_002733829.1 225853596 7676714 complement(2113642..2114865) 1 NC_012441.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2114865 7676714 BMEA_A2232 Brucella melitensis ATCC 23457 3-oxoacyl-ACP synthase YP_002733829.1 2113642 R 546272 CDS YP_002733830.1 225853597 7676715 complement(2115031..2115549) 1 NC_012441.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2115549 fabA 7676715 fabA Brucella melitensis ATCC 23457 3-hydroxydecanoyl-ACP dehydratase YP_002733830.1 2115031 R 546272 CDS YP_002733831.1 225853598 7676716 2115796..2116239 1 NC_012441.1 ferric uptake regulation protein 2116239 7676716 BMEA_A2234 Brucella melitensis ATCC 23457 ferric uptake regulation protein YP_002733831.1 2115796 D 546272 CDS YP_002733832.1 225853599 7676717 2116405..2117184 1 NC_012441.1 lipoprotein, YaeC family protein 2117184 7676717 BMEA_A2235 Brucella melitensis ATCC 23457 lipoprotein, YaeC family protein YP_002733832.1 2116405 D 546272 CDS YP_002733833.1 225853600 7676718 complement(2117229..2117774) 1 NC_012441.1 hypothetical protein 2117774 7676718 BMEA_A2236 Brucella melitensis ATCC 23457 hypothetical protein YP_002733833.1 2117229 R 546272 CDS YP_002733834.1 225853601 7676719 2118125..2119129 1 NC_012441.1 glycerate dehydrogenase 2119129 7676719 BMEA_A2237 Brucella melitensis ATCC 23457 glycerate dehydrogenase YP_002733834.1 2118125 D 546272 CDS YP_002733835.1 225853602 7676720 complement(2119154..2119855) 1 NC_012441.1 dihydrolipoyllysine-residue acetyltransferase 2119855 7676720 BMEA_A2238 Brucella melitensis ATCC 23457 dihydrolipoyllysine-residue acetyltransferase YP_002733835.1 2119154 R 546272 CDS YP_002733836.1 225853603 7676721 complement(2119877..2120749) 1 NC_012441.1 dipeptidyl-peptidase 6 2120749 7676721 BMEA_A2239 Brucella melitensis ATCC 23457 dipeptidyl-peptidase 6 YP_002733836.1 2119877 R 546272 CDS YP_002733837.1 225853604 7676722 complement(2120746..2121096) 1 NC_012441.1 MarR family transcriptional regulator 2121096 7676722 BMEA_A2240 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002733837.1 2120746 R 546272 CDS YP_002733838.1 225853605 7676723 complement(2121171..2122553) 1 NC_012441.1 cytosol aminopeptidase 2122553 7676723 BMEA_A2241 Brucella melitensis ATCC 23457 cytosol aminopeptidase YP_002733838.1 2121171 R 546272 CDS YP_002733839.1 225853606 7676724 2122657..2122956 1 NC_012441.1 hypothetical protein 2122956 7676724 BMEA_A2242 Brucella melitensis ATCC 23457 hypothetical protein YP_002733839.1 2122657 D 546272 CDS YP_002733840.1 225853607 7676725 complement(2122713..2122892) 1 NC_012441.1 hypothetical protein 2122892 7676725 BMEA_A2243 Brucella melitensis ATCC 23457 hypothetical protein YP_002733840.1 2122713 R 546272 CDS YP_002733841.1 225853608 7676726 2123112..2123993 1 NC_012441.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2123993 mutM 7676726 mutM Brucella melitensis ATCC 23457 formamidopyrimidine-DNA glycosylase YP_002733841.1 2123112 D 546272 CDS YP_002733842.1 225853609 7676727 2124120..2124893 1 NC_012441.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2124893 7676727 BMEA_A2245 Brucella melitensis ATCC 23457 enoyl-CoA hydratase YP_002733842.1 2124120 D 546272 CDS YP_002733843.1 225853610 7676728 2125229..2125495 1 NC_012441.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2125495 rpsT 7676728 rpsT Brucella melitensis ATCC 23457 30S ribosomal protein S20 YP_002733843.1 2125229 D 546272 CDS YP_002733844.1 225685872 7670527 155..1348 1 NC_012442.1 replication initiation protein RepC 1348 7670527 BMEA_B0004 Brucella melitensis ATCC 23457 replication initiation protein RepC YP_002733844.1 155 D 546272 CDS YP_002733845.1 225685873 7670528 complement(1413..1562) 1 NC_012442.1 hypothetical protein 1562 7670528 BMEA_B0005 Brucella melitensis ATCC 23457 hypothetical protein YP_002733845.1 1413 R 546272 CDS YP_002733846.1 225685874 7670529 1551..1814 1 NC_012442.1 hypothetical protein 1814 7670529 BMEA_B0006 Brucella melitensis ATCC 23457 hypothetical protein YP_002733846.1 1551 D 546272 CDS YP_002733847.1 225685875 7670530 2092..3033 1 NC_012442.1 ribokinase 3033 rbsK 7670530 rbsK Brucella melitensis ATCC 23457 ribokinase YP_002733847.1 2092 D 546272 CDS YP_002733848.1 225685876 7670531 complement(3110..4108) 1 NC_012442.1 Inosine-uridine preferring nucleoside hydrolase 4108 7670531 BMEA_B0008 Brucella melitensis ATCC 23457 Inosine-uridine preferring nucleoside hydrolase YP_002733848.1 3110 R 546272 CDS YP_002733849.1 225685877 7670532 complement(4131..5042) 1 NC_012442.1 inner-membrane translocator 5042 7670532 BMEA_B0009 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002733849.1 4131 R 546272 CDS YP_002733850.1 225685878 7670533 complement(5039..6118) 1 NC_012442.1 hypothetical protein 6118 7670533 BMEA_B0010 Brucella melitensis ATCC 23457 hypothetical protein YP_002733850.1 5039 R 546272 CDS YP_002733851.1 225685879 7670534 complement(6180..7751) 1 NC_012442.1 Galactose/methyl galactoside import ATP-binding protein mglA 7751 7670534 BMEA_B0011 Brucella melitensis ATCC 23457 Galactose/methyl galactoside import ATP-binding protein mglA YP_002733851.1 6180 R 546272 CDS YP_002733852.1 225685880 7670536 9104..9712 1 NC_012442.1 hypothetical protein 9712 7670536 BMEA_B0013 Brucella melitensis ATCC 23457 hypothetical protein YP_002733852.1 9104 D 546272 CDS YP_002733853.1 225685881 7670538 complement(10398..11174) 1 NC_012442.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 11174 7670538 BMEA_B0015 Brucella melitensis ATCC 23457 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002733853.1 10398 R 546272 CDS YP_002733854.1 225685882 7670539 complement(11174..12046) 1 NC_012442.1 putative isochorismatase 12046 7670539 BMEA_B0016 Brucella melitensis ATCC 23457 putative isochorismatase YP_002733854.1 11174 R 546272 CDS YP_002733855.1 225685883 7670540 complement(12098..13717) 1 NC_012442.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 13717 entE 7670540 entE Brucella melitensis ATCC 23457 enterobactin synthase subunit E YP_002733855.1 12098 R 546272 CDS YP_002733856.1 225685884 7670541 complement(13824..14999) 1 NC_012442.1 isochorismate synthase 14999 7670541 BMEA_B0018 Brucella melitensis ATCC 23457 isochorismate synthase YP_002733856.1 13824 R 546272 CDS YP_002733857.1 225685885 7670542 15071..16480 1 NC_012442.1 Linear gramicidin synthetase subunit B 16480 7670542 BMEA_B0019 Brucella melitensis ATCC 23457 Linear gramicidin synthetase subunit B YP_002733857.1 15071 D 546272 CDS YP_002733858.1 225685886 7670543 complement(16528..17316) 1 NC_012442.1 oxidoreductase, molybdopterin-binding 17316 7670543 BMEA_B0020 Brucella melitensis ATCC 23457 oxidoreductase, molybdopterin-binding YP_002733858.1 16528 R 546272 CDS YP_002733859.1 225685887 7670544 complement(17313..18122) 1 NC_012442.1 HupC/HyaC/HydC family protein 18122 7670544 BMEA_B0021 Brucella melitensis ATCC 23457 HupC/HyaC/HydC family protein YP_002733859.1 17313 R 546272 CDS YP_002733860.1 225685888 7670545 complement(18185..18454) 1 NC_012442.1 pentapeptide MXKDX repeat protein 18454 7670545 BMEA_B0022 Brucella melitensis ATCC 23457 pentapeptide MXKDX repeat protein YP_002733860.1 18185 R 546272 CDS YP_002733861.1 225685889 7670546 18639..19163 1 NC_012442.1 RNA polymerase sigma factor, sigma-70 family protein 19163 7670546 BMEA_B0023 Brucella melitensis ATCC 23457 RNA polymerase sigma factor, sigma-70 family protein YP_002733861.1 18639 D 546272 CDS YP_002733862.1 225685890 7670547 19138..19788 1 NC_012442.1 hypothetical protein 19788 7670547 BMEA_B0024 Brucella melitensis ATCC 23457 hypothetical protein YP_002733862.1 19138 D 546272 CDS YP_002733863.1 225685891 7670548 complement(19834..20574) 1 NC_012442.1 GntR family transcriptional regulator 20574 7670548 BMEA_B0025 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002733863.1 19834 R 546272 CDS YP_002733864.1 225685892 7670549 20692..22107 1 NC_012442.1 Leu/Ile/Val-binding protein family protein 22107 7670549 BMEA_B0026 Brucella melitensis ATCC 23457 Leu/Ile/Val-binding protein family protein YP_002733864.1 20692 D 546272 CDS YP_002733865.1 225685893 7670550 22149..23138 1 NC_012442.1 inner-membrane translocator 23138 7670550 BMEA_B0027 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002733865.1 22149 D 546272 CDS YP_002733866.1 225685894 7670551 23142..24362 1 NC_012442.1 inner-membrane translocator 24362 7670551 BMEA_B0028 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002733866.1 23142 D 546272 CDS YP_002733867.1 225685895 7670552 24362..25114 1 NC_012442.1 ABC transporter 25114 7670552 BMEA_B0029 Brucella melitensis ATCC 23457 ABC transporter YP_002733867.1 24362 D 546272 CDS YP_002733868.1 225685896 7670553 25114..25830 1 NC_012442.1 ABC transporter 25830 7670553 BMEA_B0030 Brucella melitensis ATCC 23457 ABC transporter YP_002733868.1 25114 D 546272 CDS YP_002733869.1 225685897 7670554 25882..26364 1 NC_012442.1 hypothetical protein 26364 7670554 BMEA_B0031 Brucella melitensis ATCC 23457 hypothetical protein YP_002733869.1 25882 D 546272 CDS YP_002733870.1 225685898 7670555 26368..27105 1 NC_012442.1 short-chain dehydrogenase/reductase SDR 27105 7670555 BMEA_B0032 Brucella melitensis ATCC 23457 short-chain dehydrogenase/reductase SDR YP_002733870.1 26368 D 546272 CDS YP_002733871.1 225685899 7670556 27354..27875 1 NC_012442.1 cyclopentanol dehydrogenase 27875 7670556 BMEA_B0033 Brucella melitensis ATCC 23457 cyclopentanol dehydrogenase YP_002733871.1 27354 D 546272 CDS YP_002733872.1 225685900 7670558 30192..31457 1 NC_012442.1 branched-chain alpha-keto acid dehydrogenase subunit E2 31457 7670558 BMEA_B0035 Brucella melitensis ATCC 23457 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002733872.1 30192 D 546272 CDS YP_002733873.1 225685901 7670559 31558..32343 1 NC_012442.1 Shikimate dehydrogenase 32343 7670559 BMEA_B0036 Brucella melitensis ATCC 23457 Shikimate dehydrogenase YP_002733873.1 31558 D 546272 CDS YP_002733874.1 225685902 7670560 32623..32916 1 NC_012442.1 hypothetical protein 32916 7670560 BMEA_B0037 Brucella melitensis ATCC 23457 hypothetical protein YP_002733874.1 32623 D 546272 CDS YP_002733875.1 225685903 7670561 complement(32870..33151) 1 NC_012442.1 hypothetical protein 33151 7670561 BMEA_B0038 Brucella melitensis ATCC 23457 hypothetical protein YP_002733875.1 32870 R 546272 CDS YP_002733876.1 225685904 7670562 33269..35986 1 NC_012442.1 magnesium-translocating P-type ATPase 35986 mgtA 7670562 mgtA Brucella melitensis ATCC 23457 magnesium-translocating P-type ATPase YP_002733876.1 33269 D 546272 CDS YP_002733877.1 225685905 7670563 36071..36421 1 NC_012442.1 hypothetical protein 36421 7670563 BMEA_B0040 Brucella melitensis ATCC 23457 hypothetical protein YP_002733877.1 36071 D 546272 CDS YP_002733878.1 225685906 7670564 36552..36755 1 NC_012442.1 hypothetical protein 36755 7670564 BMEA_B0041 Brucella melitensis ATCC 23457 hypothetical protein YP_002733878.1 36552 D 546272 CDS YP_002733879.1 225685907 7670565 36757..37473 1 NC_012442.1 MgtC-magnesium transport family protein 37473 7670565 BMEA_B0042 Brucella melitensis ATCC 23457 MgtC-magnesium transport family protein YP_002733879.1 36757 D 546272 CDS YP_002733880.1 225685908 7670566 37548..38618 1 NC_012442.1 sensor nodulation protein 38618 7670566 BMEA_B0043 Brucella melitensis ATCC 23457 sensor nodulation protein YP_002733880.1 37548 D 546272 CDS YP_002733881.1 225685909 7670567 38615..39253 1 NC_012442.1 C4-dicarboxylate transport transcriptional regulatory protein dctR 39253 7670567 BMEA_B0044 Brucella melitensis ATCC 23457 C4-dicarboxylate transport transcriptional regulatory protein dctR YP_002733881.1 38615 D 546272 CDS YP_002733882.1 225685910 7670569 complement(39639..40001) 1 NC_012442.1 hypothetical protein 40001 7670569 BMEA_B0046 Brucella melitensis ATCC 23457 hypothetical protein YP_002733882.1 39639 R 546272 CDS YP_002733883.1 225685911 7670570 40320..41210 1 NC_012442.1 N-formylglutamate amidohydrolase 41210 7670570 BMEA_B0047 Brucella melitensis ATCC 23457 N-formylglutamate amidohydrolase YP_002733883.1 40320 D 546272 CDS YP_002733884.1 225685912 7670571 41372..42148 1 NC_012442.1 histidinol-phosphate phosphatase 42148 7670571 BMEA_B0048 Brucella melitensis ATCC 23457 histidinol-phosphate phosphatase YP_002733884.1 41372 D 546272 CDS YP_002733885.1 225685913 7670572 complement(42199..43194) 1 NC_012442.1 Lysophospholipase 43194 7670572 BMEA_B0049 Brucella melitensis ATCC 23457 Lysophospholipase YP_002733885.1 42199 R 546272 CDS YP_002733886.1 225685914 7670573 complement(43234..43449) 1 NC_012442.1 hypothetical protein 43449 7670573 BMEA_B0050 Brucella melitensis ATCC 23457 hypothetical protein YP_002733886.1 43234 R 546272 CDS YP_002733887.1 225685915 7670574 complement(43544..43942) 1 NC_012442.1 hypothetical protein 43942 7670574 BMEA_B0051 Brucella melitensis ATCC 23457 hypothetical protein YP_002733887.1 43544 R 546272 CDS YP_002733888.1 225685916 7670575 43994..44203 1 NC_012442.1 hypothetical protein 44203 7670575 BMEA_B0053 Brucella melitensis ATCC 23457 hypothetical protein YP_002733888.1 43994 D 546272 CDS YP_002733889.1 225685917 7670576 44176..44427 1 NC_012442.1 hypothetical protein 44427 7670576 BMEA_B0054 Brucella melitensis ATCC 23457 hypothetical protein YP_002733889.1 44176 D 546272 CDS YP_002733890.1 225685918 7670577 44506..44976 1 NC_012442.1 Small heat shock protein hspD 44976 7670577 BMEA_B0055 Brucella melitensis ATCC 23457 Small heat shock protein hspD YP_002733890.1 44506 D 546272 CDS YP_002733891.1 225685919 7670578 complement(45114..46163) 1 NC_012442.1 Low specificity L-threonine aldolase 46163 7670578 BMEA_B0056 Brucella melitensis ATCC 23457 Low specificity L-threonine aldolase YP_002733891.1 45114 R 546272 CDS YP_002733892.1 225685920 7670579 complement(46432..46716) 1 NC_012442.1 hypothetical protein 46716 7670579 BMEA_B0057 Brucella melitensis ATCC 23457 hypothetical protein YP_002733892.1 46432 R 546272 CDS YP_002733893.1 225685921 7670580 46806..51557 1 NC_012442.1 glutamate synthase, large subunit 51557 7670580 BMEA_B0058 Brucella melitensis ATCC 23457 glutamate synthase, large subunit YP_002733893.1 46806 D 546272 CDS YP_002733894.1 225685922 7670581 51639..53093 1 NC_012442.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 53093 gltD 7670581 gltD Brucella melitensis ATCC 23457 glutamate synthase subunit beta YP_002733894.1 51639 D 546272 CDS YP_002733895.1 225685923 7670582 complement(53138..54541) 1 NC_012442.1 amino acid permease-associated protein 54541 7670582 BMEA_B0060 Brucella melitensis ATCC 23457 amino acid permease-associated protein YP_002733895.1 53138 R 546272 CDS YP_002733896.1 225685924 7670583 complement(54759..55910) 1 NC_012442.1 hypothetical protein 55910 7670583 BMEA_B0061 Brucella melitensis ATCC 23457 hypothetical protein YP_002733896.1 54759 R 546272 CDS YP_002733897.1 225685925 7670584 complement(56161..56679) 1 NC_012442.1 TraQ protein 56679 7670584 BMEA_B0062 Brucella melitensis ATCC 23457 TraQ protein YP_002733897.1 56161 R 546272 CDS YP_002733898.1 225685926 7670585 complement(56825..57913) 1 NC_012442.1 P-type DNA transfer ATPase VirB11 57913 7670585 BMEA_B0063 Brucella melitensis ATCC 23457 P-type DNA transfer ATPase VirB11 YP_002733898.1 56825 R 546272 CDS YP_002733899.1 225685927 7670586 complement(57894..59045) 1 NC_012442.1 type IV secretion system protein virB10 59045 7670586 BMEA_B0064 Brucella melitensis ATCC 23457 type IV secretion system protein virB10 YP_002733899.1 57894 R 546272 CDS YP_002733900.1 225685928 7670587 complement(59042..59911) 1 NC_012442.1 P-type conjugative transfer protein VirB9 59911 7670587 BMEA_B0065 Brucella melitensis ATCC 23457 P-type conjugative transfer protein VirB9 YP_002733900.1 59042 R 546272 CDS YP_002733901.1 225685929 7670588 complement(59908..60627) 1 NC_012442.1 type IV secretion system protein virB8 60627 7670588 BMEA_B0066 Brucella melitensis ATCC 23457 type IV secretion system protein virB8 YP_002733901.1 59908 R 546272 CDS YP_002733902.1 225685930 7670589 complement(60630..60803) 1 NC_012442.1 TraI protein 60803 7670589 BMEA_B0067 Brucella melitensis ATCC 23457 TraI protein YP_002733902.1 60630 R 546272 CDS YP_002733903.1 225685931 7670590 complement(60967..62010) 1 NC_012442.1 protein virB6 62010 7670590 BMEA_B0068 Brucella melitensis ATCC 23457 protein virB6 YP_002733903.1 60967 R 546272 CDS YP_002733904.1 225685932 7670591 complement(62194..62910) 1 NC_012442.1 P-type DNA transfer protein VirB5 62910 7670591 BMEA_B0069 Brucella melitensis ATCC 23457 P-type DNA transfer protein VirB5 YP_002733904.1 62194 R 546272 CDS YP_002733905.1 225685933 7670592 complement(62915..65410) 1 NC_012442.1 type IV secretion/conjugal transfer ATPase, VirB4 family protein 65410 7670592 BMEA_B0070 Brucella melitensis ATCC 23457 type IV secretion/conjugal transfer ATPase, VirB4 family protein YP_002733905.1 62915 R 546272 CDS YP_002733906.1 225685934 7670593 complement(65410..65760) 1 NC_012442.1 type IV secretory pathway VirB3 family protein 65760 7670593 BMEA_B0071 Brucella melitensis ATCC 23457 type IV secretory pathway VirB3 family protein YP_002733906.1 65410 R 546272 CDS YP_002733907.1 225685935 7670594 complement(65774..66091) 1 NC_012442.1 conjugal transfer protein TrbC 66091 7670594 BMEA_B0072 Brucella melitensis ATCC 23457 conjugal transfer protein TrbC YP_002733907.1 65774 R 546272 CDS YP_002733908.1 225685936 7670595 complement(66527..67243) 1 NC_012442.1 Lytic transglycosylase catalytic 67243 7670595 BMEA_B0073 Brucella melitensis ATCC 23457 Lytic transglycosylase catalytic YP_002733908.1 66527 R 546272 CDS YP_002733909.1 225685937 7670596 complement(67747..68985) 1 NC_012442.1 lytic murein transglycosylase 68985 7670596 BMEA_B0074 Brucella melitensis ATCC 23457 lytic murein transglycosylase YP_002733909.1 67747 R 546272 CDS YP_002733910.1 225685938 7670597 69385..70278 1 NC_012442.1 UTP-glucose-1-phosphate uridylyltransferase 70278 galU 7670597 galU Brucella melitensis ATCC 23457 UTP-glucose-1-phosphate uridylyltransferase YP_002733910.1 69385 D 546272 CDS YP_002733911.1 225685939 7670598 complement(70331..71869) 1 NC_012442.1 hypothetical protein 71869 7670598 BMEA_B0076 Brucella melitensis ATCC 23457 hypothetical protein YP_002733911.1 70331 R 546272 CDS YP_002733912.1 225685940 7670599 72010..73011 1 NC_012442.1 sugar isomerase, KpsF/GutQ family protein 73011 7670599 BMEA_B0077 Brucella melitensis ATCC 23457 sugar isomerase, KpsF/GutQ family protein YP_002733912.1 72010 D 546272 CDS YP_002733913.1 225685941 7670600 complement(73150..73617) 1 NC_012442.1 hypothetical protein 73617 7670600 BMEA_B0078 Brucella melitensis ATCC 23457 hypothetical protein YP_002733913.1 73150 R 546272 CDS YP_002733914.1 225685942 7670601 complement(73638..74624) 1 NC_012442.1 band 7 protein 74624 7670601 BMEA_B0079 Brucella melitensis ATCC 23457 band 7 protein YP_002733914.1 73638 R 546272 CDS YP_002733915.1 225685943 7670602 complement(74757..75815) 1 NC_012442.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 75815 hemH 7670602 hemH Brucella melitensis ATCC 23457 ferrochelatase YP_002733915.1 74757 R 546272 CDS YP_002733916.1 225685944 7670603 complement(75953..76333) 1 NC_012442.1 hypothetical protein 76333 7670603 BMEA_B0081 Brucella melitensis ATCC 23457 hypothetical protein YP_002733916.1 75953 R 546272 CDS YP_002733917.1 225685945 7670605 complement(78032..78712) 1 NC_012442.1 hypothetical protein 78712 7670605 BMEA_B0083 Brucella melitensis ATCC 23457 hypothetical protein YP_002733917.1 78032 R 546272 CDS YP_002733918.1 225685946 7670606 complement(78646..79815) 1 NC_012442.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase 79815 pabB 7670606 pabB Brucella melitensis ATCC 23457 aminodeoxychorismate synthase YP_002733918.1 78646 R 546272 CDS YP_002733919.1 225685947 7670607 complement(79825..81687) 1 NC_012442.1 oligoendopeptidase, pepF/M3 family protein 81687 7670607 BMEA_B0085 Brucella melitensis ATCC 23457 oligoendopeptidase, pepF/M3 family protein YP_002733919.1 79825 R 546272 CDS YP_002733920.1 225685948 7670608 82035..83525 1 NC_012442.1 two component, sigma54 specific, transcriptional regulator, Fis family protein 83525 7670608 BMEA_B0086 Brucella melitensis ATCC 23457 two component, sigma54 specific, transcriptional regulator, Fis family protein YP_002733920.1 82035 D 546272 CDS YP_002733921.1 225685949 7670609 83866..85779 1 NC_012442.1 hypothetical protein 85779 7670609 BMEA_B0087 Brucella melitensis ATCC 23457 hypothetical protein YP_002733921.1 83866 D 546272 CDS YP_002733922.1 225685950 7670610 complement(85845..86483) 1 NC_012442.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 86483 eda 7670610 eda Brucella melitensis ATCC 23457 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002733922.1 85845 R 546272 CDS YP_002733923.1 225685951 7670611 complement(86642..87253) 1 NC_012442.1 hypothetical protein 87253 7670611 BMEA_B0089 Brucella melitensis ATCC 23457 hypothetical protein YP_002733923.1 86642 R 546272 CDS YP_002733924.1 225685952 7670612 87384..88301 1 NC_012442.1 rhodanese family protein 88301 7670612 BMEA_B0090 Brucella melitensis ATCC 23457 rhodanese family protein YP_002733924.1 87384 D 546272 CDS YP_002733925.1 225685953 7670613 88336..88542 1 NC_012442.1 hypothetical protein 88542 7670613 BMEA_B0091 Brucella melitensis ATCC 23457 hypothetical protein YP_002733925.1 88336 D 546272 CDS YP_002733926.1 225685954 7670614 88582..89337 1 NC_012442.1 molybdate ABC transporter substrate-binding protein 89337 modA 7670614 modA Brucella melitensis ATCC 23457 molybdate ABC transporter substrate-binding protein YP_002733926.1 88582 D 546272 CDS YP_002733927.1 225685955 7670615 89348..90034 1 NC_012442.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 90034 modB 7670615 modB Brucella melitensis ATCC 23457 molybdate ABC transporter permease YP_002733927.1 89348 D 546272 CDS YP_002733928.1 225685956 7670616 90031..91110 1 NC_012442.1 molybdate ABC transporter ATP-binding protein 91110 modC 7670616 modC Brucella melitensis ATCC 23457 molybdate ABC transporter ATP-binding protein YP_002733928.1 90031 D 546272 CDS YP_002733929.1 225685957 7670617 91180..91857 1 NC_012442.1 GCN5-related N-acetyltransferase 91857 7670617 BMEA_B0095 Brucella melitensis ATCC 23457 GCN5-related N-acetyltransferase YP_002733929.1 91180 D 546272 CDS YP_002733930.1 225685958 7670618 91850..92053 1 NC_012442.1 hypothetical protein 92053 7670618 BMEA_B0096 Brucella melitensis ATCC 23457 hypothetical protein YP_002733930.1 91850 D 546272 CDS YP_002733931.1 225685959 7670619 92145..92300 1 NC_012442.1 hypothetical protein 92300 7670619 BMEA_B0097 Brucella melitensis ATCC 23457 hypothetical protein YP_002733931.1 92145 D 546272 CDS YP_002733932.1 225685960 7670620 complement(92995..94098) 1 NC_012442.1 high-affinity nickel-transporter 94098 7670620 BMEA_B0098 Brucella melitensis ATCC 23457 high-affinity nickel-transporter YP_002733932.1 92995 R 546272 CDS YP_002733933.1 225685961 7670621 complement(94098..94802) 1 NC_012442.1 hypothetical protein 94802 7670621 BMEA_B0099 Brucella melitensis ATCC 23457 hypothetical protein YP_002733933.1 94098 R 546272 CDS YP_002733934.1 225685962 7670622 complement(94842..95735) 1 NC_012442.1 LysR family transcriptional regulator 95735 7670622 BMEA_B0100 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002733934.1 94842 R 546272 CDS YP_002733935.1 225685963 7670623 complement(95739..96944) 1 NC_012442.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 96944 7670623 BMEA_B0101 Brucella melitensis ATCC 23457 amidase YP_002733935.1 95739 R 546272 CDS YP_002733936.1 225685964 7670624 97529..98662 1 NC_012442.1 Lysine/ornithine decarboxylase 98662 7670624 BMEA_B0103 Brucella melitensis ATCC 23457 Lysine/ornithine decarboxylase YP_002733936.1 97529 D 546272 CDS YP_002733937.1 225685965 7670625 complement(98738..100456) 1 NC_012442.1 lipopolysaccharide biosynthesis protein 100456 7670625 BMEA_B0104 Brucella melitensis ATCC 23457 lipopolysaccharide biosynthesis protein YP_002733937.1 98738 R 546272 CDS YP_002733938.1 225685966 7670626 complement(100473..100610) 1 NC_012442.1 hypothetical protein 100610 7670626 BMEA_B0105 Brucella melitensis ATCC 23457 hypothetical protein YP_002733938.1 100473 R 546272 CDS YP_002733939.1 225685967 7670627 complement(100582..101484) 1 NC_012442.1 hypothetical protein 101484 7670627 BMEA_B0106 Brucella melitensis ATCC 23457 hypothetical protein YP_002733939.1 100582 R 546272 CDS YP_002733940.1 225685968 7670628 complement(101442..102203) 1 NC_012442.1 WecB/TagA/CpsF family protein glycosyl transferase 102203 7670628 BMEA_B0107 Brucella melitensis ATCC 23457 WecB/TagA/CpsF family protein glycosyl transferase YP_002733940.1 101442 R 546272 CDS YP_002733941.1 225685969 7670629 complement(102204..103394) 1 NC_012442.1 hypothetical protein 103394 7670629 BMEA_B0108 Brucella melitensis ATCC 23457 hypothetical protein YP_002733941.1 102204 R 546272 CDS YP_002733942.1 225685970 7670630 103530..104522 1 NC_012442.1 glycosyl transferase family 2 protein 104522 7670630 BMEA_B0110 Brucella melitensis ATCC 23457 glycosyl transferase family 2 protein YP_002733942.1 103530 D 546272 CDS YP_002733943.1 225685971 7670631 104491..105816 1 NC_012442.1 O-antigen polymerase 105816 7670631 BMEA_B0111 Brucella melitensis ATCC 23457 O-antigen polymerase YP_002733943.1 104491 D 546272 CDS YP_002733944.1 225685972 7670633 complement(106963..108012) 1 NC_012442.1 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 108012 7670633 BMEA_B0113 Brucella melitensis ATCC 23457 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase YP_002733944.1 106963 R 546272 CDS YP_002733945.1 225685973 7670634 108329..109738 1 NC_012442.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 109738 gnd 7670634 gnd Brucella melitensis ATCC 23457 6-phosphogluconate dehydrogenase YP_002733945.1 108329 D 546272 CDS YP_002733946.1 225685974 7670635 complement(109834..110895) 1 NC_012442.1 polyamine ABC transporter ATP-binding protein 110895 7670635 BMEA_B0115 Brucella melitensis ATCC 23457 polyamine ABC transporter ATP-binding protein YP_002733946.1 109834 R 546272 CDS YP_002733947.1 225685975 7670636 complement(110901..111719) 1 NC_012442.1 hypothetical protein 111719 7670636 BMEA_B0116 Brucella melitensis ATCC 23457 hypothetical protein YP_002733947.1 110901 R 546272 CDS YP_002733948.1 225685976 7670637 complement(111716..112609) 1 NC_012442.1 hypothetical protein 112609 7670637 BMEA_B0117 Brucella melitensis ATCC 23457 hypothetical protein YP_002733948.1 111716 R 546272 CDS YP_002733949.1 225685977 7670638 complement(112818..113921) 1 NC_012442.1 family 1 extracellular solute-binding protein 113921 7670638 BMEA_B0118 Brucella melitensis ATCC 23457 family 1 extracellular solute-binding protein YP_002733949.1 112818 R 546272 CDS YP_002733950.1 225685978 7670639 complement(114330..115907) 1 NC_012442.1 drug resistance transporter, EmrB/QacA subfamily protein 115907 7670639 BMEA_B0119 Brucella melitensis ATCC 23457 drug resistance transporter, EmrB/QacA subfamily protein YP_002733950.1 114330 R 546272 CDS YP_002733951.1 225685979 7670640 complement(116000..117241) 1 NC_012442.1 secretion protein HlyD family protein 117241 7670640 BMEA_B0120 Brucella melitensis ATCC 23457 secretion protein HlyD family protein YP_002733951.1 116000 R 546272 CDS YP_002733952.1 225685980 7670641 117342..118085 1 NC_012442.1 TetR family transcriptional regulator 118085 7670641 BMEA_B0121 Brucella melitensis ATCC 23457 TetR family transcriptional regulator YP_002733952.1 117342 D 546272 CDS YP_002733953.1 225685981 7670642 118359..119138 1 NC_012442.1 regulatory protein LuxR 119138 7670642 BMEA_B0122 Brucella melitensis ATCC 23457 regulatory protein LuxR YP_002733953.1 118359 D 546272 CDS YP_002733954.1 225685982 7670643 complement(119207..119626) 1 NC_012442.1 hypothetical protein 119626 7670643 BMEA_B0123 Brucella melitensis ATCC 23457 hypothetical protein YP_002733954.1 119207 R 546272 CDS YP_002733955.1 225685983 7670644 complement(119746..120816) 1 NC_012442.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 120816 flhB 7670644 flhB Brucella melitensis ATCC 23457 flagellar biosynthesis protein FlhB YP_002733955.1 119746 R 546272 CDS YP_002733956.1 225685984 7670646 complement(121822..122142) 1 NC_012442.1 flagellar motor switch protein FliN 122142 fliN 7670646 fliN Brucella melitensis ATCC 23457 flagellar motor switch protein FliN YP_002733956.1 121822 R 546272 CDS YP_002733957.1 225685985 7670647 complement(122166..122627) 1 NC_012442.1 hypothetical protein 122627 7670647 BMEA_B0127 Brucella melitensis ATCC 23457 hypothetical protein YP_002733957.1 122166 R 546272 CDS YP_002733958.1 225685986 7670648 complement(122608..123558) 1 NC_012442.1 Flagellar motor switch protein fliM 123558 7670648 BMEA_B0128 Brucella melitensis ATCC 23457 Flagellar motor switch protein fliM YP_002733958.1 122608 R 546272 CDS YP_002733959.1 225685987 7670649 complement(123560..124432) 1 NC_012442.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 124432 7670649 BMEA_B0129 Brucella melitensis ATCC 23457 flagellar motor protein MotA YP_002733959.1 123560 R 546272 CDS YP_002733960.1 225685988 7670650 124578..125366 1 NC_012442.1 hypothetical protein 125366 7670650 BMEA_B0130 Brucella melitensis ATCC 23457 hypothetical protein YP_002733960.1 124578 D 546272 CDS YP_002733961.1 225685989 7670651 125366..126097 1 NC_012442.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgF 126097 flgF 7670651 flgF Brucella melitensis ATCC 23457 flagellar basal body rod protein FlgF YP_002733961.1 125366 D 546272 CDS YP_002733962.1 225685990 7670652 126094..127455 1 NC_012442.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 127455 fliI 7670652 fliI Brucella melitensis ATCC 23457 flagellum-specific ATP synthase YP_002733962.1 126094 D 546272 CDS YP_002733963.1 225685991 7670653 127779..128057 1 NC_012442.1 hypothetical protein 128057 7670653 BMEA_B0134 Brucella melitensis ATCC 23457 hypothetical protein YP_002733963.1 127779 D 546272 CDS YP_002733964.1 225685992 7670654 complement(128082..129059) 1 NC_012442.1 bacitracin transport permease BCRC 129059 7670654 BMEA_B0135 Brucella melitensis ATCC 23457 bacitracin transport permease BCRC YP_002733964.1 128082 R 546272 CDS YP_002733965.1 225685993 7670655 129047..129202 1 NC_012442.1 hypothetical protein 129202 7670655 BMEA_B0136 Brucella melitensis ATCC 23457 hypothetical protein YP_002733965.1 129047 D 546272 CDS YP_002733966.1 225685994 7670656 complement(129357..129575) 1 NC_012442.1 hypothetical protein 129575 7670656 BMEA_B0137 Brucella melitensis ATCC 23457 hypothetical protein YP_002733966.1 129357 R 546272 CDS YP_002733967.1 225685995 7670657 129603..129992 1 NC_012442.1 hypothetical protein 129992 7670657 BMEA_B0138 Brucella melitensis ATCC 23457 hypothetical protein YP_002733967.1 129603 D 546272 CDS YP_002733968.1 225685996 7670658 129989..130969 1 NC_012442.1 glycosyl transferase family 2 protein 130969 7670658 BMEA_B0139 Brucella melitensis ATCC 23457 glycosyl transferase family 2 protein YP_002733968.1 129989 D 546272 CDS YP_002733969.1 225685997 7670659 130950..131702 1 NC_012442.1 YdjC family protein 131702 7670659 BMEA_B0140 Brucella melitensis ATCC 23457 YdjC family protein YP_002733969.1 130950 D 546272 CDS YP_002733970.1 225685998 7670660 131699..133135 1 NC_012442.1 dolichyl-phosphate-mannose-protein mannosyltransferase family protein 133135 7670660 BMEA_B0141 Brucella melitensis ATCC 23457 dolichyl-phosphate-mannose-protein mannosyltransferase family protein YP_002733970.1 131699 D 546272 CDS YP_002733971.1 225685999 7670661 133337..134335 1 NC_012442.1 helix-turn-helix- domain containing protein 134335 7670661 BMEA_B0142 Brucella melitensis ATCC 23457 helix-turn-helix- domain containing protein YP_002733971.1 133337 D 546272 CDS YP_002733972.1 225686000 7670662 134691..135128 1 NC_012442.1 putative transcriptional regulator protein 135128 7670662 BMEA_B0143 Brucella melitensis ATCC 23457 putative transcriptional regulator protein YP_002733972.1 134691 D 546272 CDS YP_002733973.1 225686001 7670663 complement(135322..136623) 1 NC_012442.1 tartrate transporter 136623 7670663 BMEA_B0144 Brucella melitensis ATCC 23457 tartrate transporter YP_002733973.1 135322 R 546272 CDS YP_002733974.1 225686002 7670664 complement(136649..137281) 1 NC_012442.1 putative aldolase 137281 7670664 BMEA_B0145 Brucella melitensis ATCC 23457 putative aldolase YP_002733974.1 136649 R 546272 CDS YP_002733975.1 225686003 7670665 complement(137307..138272) 1 NC_012442.1 NAD-dependent epimerase/dehydratase 138272 7670665 BMEA_B0146 Brucella melitensis ATCC 23457 NAD-dependent epimerase/dehydratase YP_002733975.1 137307 R 546272 CDS YP_002733976.1 225686004 7670666 complement(138272..139063) 1 NC_012442.1 DeoR family transcriptional regulator 139063 7670666 BMEA_B0147 Brucella melitensis ATCC 23457 DeoR family transcriptional regulator YP_002733976.1 138272 R 546272 CDS YP_002733977.1 225686005 7670667 complement(139060..139845) 1 NC_012442.1 AP endonuclease, family 2 139845 7670667 BMEA_B0148 Brucella melitensis ATCC 23457 AP endonuclease, family 2 YP_002733977.1 139060 R 546272 CDS YP_002733978.1 225686006 7670668 complement(139845..141119) 1 NC_012442.1 hypothetical protein 141119 7670668 BMEA_B0149 Brucella melitensis ATCC 23457 hypothetical protein YP_002733978.1 139845 R 546272 CDS YP_002733979.1 225686007 7670669 complement(141121..142029) 1 NC_012442.1 2-hydroxy-3-oxopropionate reductase 142029 7670669 BMEA_B0150 Brucella melitensis ATCC 23457 2-hydroxy-3-oxopropionate reductase YP_002733979.1 141121 R 546272 CDS YP_002733980.1 225686008 7670670 142179..142316 1 NC_012442.1 hypothetical protein 142316 7670670 BMEA_B0151 Brucella melitensis ATCC 23457 hypothetical protein YP_002733980.1 142179 D 546272 CDS YP_002733981.1 225686009 7670671 142393..142773 1 NC_012442.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal body rod protein FlgB 142773 flgB 7670671 flgB Brucella melitensis ATCC 23457 flagellar basal body rod protein FlgB YP_002733981.1 142393 D 546272 CDS YP_002733982.1 225686010 7670672 142776..143198 1 NC_012442.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 143198 flgC 7670672 flgC Brucella melitensis ATCC 23457 flagellar basal body rod protein FlgC YP_002733982.1 142776 D 546272 CDS YP_002733983.1 225686011 7670673 143198..143533 1 NC_012442.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar hook-basal body protein FliE 143533 fliE 7670673 fliE Brucella melitensis ATCC 23457 flagellar hook-basal body protein FliE YP_002733983.1 143198 D 546272 CDS YP_002733984.1 225686012 7670674 143619..144407 1 NC_012442.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; flagellar basal body rod protein FlgG 144407 flgG 7670674 flgG Brucella melitensis ATCC 23457 flagellar basal body rod protein FlgG YP_002733984.1 143619 D 546272 CDS YP_002733985.1 225686013 7670675 144419..144901 1 NC_012442.1 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body P-ring biosynthesis protein FlgA 144901 flgA 7670675 flgA Brucella melitensis ATCC 23457 flagellar basal body P-ring biosynthesis protein FlgA YP_002733985.1 144419 D 546272 CDS YP_002733986.1 225686014 7670676 144937..146271 1 NC_012442.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 146271 flgI 7670676 flgI Brucella melitensis ATCC 23457 flagellar basal body P-ring protein YP_002733986.1 144937 D 546272 CDS YP_002733987.1 225686015 7670677 146268..146828 1 NC_012442.1 hypothetical protein 146828 7670677 BMEA_B0158 Brucella melitensis ATCC 23457 hypothetical protein YP_002733987.1 146268 D 546272 CDS YP_002733988.1 225686016 7670678 146837..147553 1 NC_012442.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 147553 flgH 7670678 flgH Brucella melitensis ATCC 23457 flagellar basal body L-ring protein YP_002733988.1 146837 D 546272 CDS YP_002733989.1 225686017 7670679 147566..148057 1 NC_012442.1 flagellar basal body-associated protein FliL 148057 7670679 BMEA_B0160 Brucella melitensis ATCC 23457 flagellar basal body-associated protein FliL YP_002733989.1 147566 D 546272 CDS YP_002733990.1 225686018 7670680 148054..148794 1 NC_012442.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 148794 fliP 7670680 fliP Brucella melitensis ATCC 23457 flagellar biosynthesis protein FliP YP_002733990.1 148054 D 546272 CDS YP_002733991.1 225686019 7670681 148889..149368 1 NC_012442.1 hypothetical protein 149368 7670681 BMEA_B0162 Brucella melitensis ATCC 23457 hypothetical protein YP_002733991.1 148889 D 546272 CDS YP_002733992.1 225686020 7670682 149313..149696 1 NC_012442.1 hypothetical protein 149696 7670682 BMEA_B0163 Brucella melitensis ATCC 23457 hypothetical protein YP_002733992.1 149313 D 546272 CDS YP_002733993.1 225686021 7670683 complement(149892..150776) 1 NC_012442.1 putative transcription regulator protein 150776 7670683 BMEA_B0164 Brucella melitensis ATCC 23457 putative transcription regulator protein YP_002733993.1 149892 R 546272 CDS YP_002733994.1 225686022 7670684 150828..150959 1 NC_012442.1 hypothetical protein 150959 7670684 BMEA_B0165 Brucella melitensis ATCC 23457 hypothetical protein YP_002733994.1 150828 D 546272 CDS YP_002733995.1 225686023 7670685 150956..152173 1 NC_012442.1 L-carnitine dehydratase/bile acid-inducible protein F 152173 7670685 BMEA_B0167 Brucella melitensis ATCC 23457 L-carnitine dehydratase/bile acid-inducible protein F YP_002733995.1 150956 D 546272 CDS YP_002733996.1 225686024 7670686 152241..153077 1 NC_012442.1 hypothetical protein 153077 7670686 BMEA_B0168 Brucella melitensis ATCC 23457 hypothetical protein YP_002733996.1 152241 D 546272 CDS YP_002733997.1 225686025 7670687 153071..153895 1 NC_012442.1 HpcH/HpaI aldolase 153895 7670687 BMEA_B0169 Brucella melitensis ATCC 23457 HpcH/HpaI aldolase YP_002733997.1 153071 D 546272 CDS YP_002733998.1 225686026 7670688 153928..154080 1 NC_012442.1 hypothetical protein 154080 7670688 BMEA_B0170 Brucella melitensis ATCC 23457 hypothetical protein YP_002733998.1 153928 D 546272 CDS YP_002733999.1 225686027 7670689 154345..154923 1 NC_012442.1 cytochrome B561 154923 7670689 BMEA_B0171 Brucella melitensis ATCC 23457 cytochrome B561 YP_002733999.1 154345 D 546272 CDS YP_002734000.1 225686028 7670690 155713..156117 1 NC_012442.1 arylsulfatase 156117 7670690 BMEA_B0172 Brucella melitensis ATCC 23457 arylsulfatase YP_002734000.1 155713 D 546272 CDS YP_002734001.1 225686029 7670692 159475..159870 1 NC_012442.1 cytochrome c2 159870 7670692 BMEA_B0174 Brucella melitensis ATCC 23457 cytochrome c2 YP_002734001.1 159475 D 546272 CDS YP_002734002.1 225686030 7670693 complement(160094..160333) 1 NC_012442.1 hypothetical protein 160333 7670693 BMEA_B0175 Brucella melitensis ATCC 23457 hypothetical protein YP_002734002.1 160094 R 546272 CDS YP_002734003.1 225686031 7670694 160763..160900 1 NC_012442.1 hypothetical protein 160900 7670694 BMEA_B0176 Brucella melitensis ATCC 23457 hypothetical protein YP_002734003.1 160763 D 546272 CDS YP_002734004.1 225686032 7670695 complement(160978..161790) 1 NC_012442.1 GntR family transcriptional regulator 161790 7670695 BMEA_B0177 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734004.1 160978 R 546272 CDS YP_002734005.1 225686033 7670696 complement(161912..162832) 1 NC_012442.1 hypothetical protein 162832 7670696 BMEA_B0178 Brucella melitensis ATCC 23457 hypothetical protein YP_002734005.1 161912 R 546272 CDS YP_002734006.1 225686034 7670697 complement(162992..163111) 1 NC_012442.1 hypothetical protein 163111 7670697 BMEA_B0179 Brucella melitensis ATCC 23457 hypothetical protein YP_002734006.1 162992 R 546272 CDS YP_002734007.1 225686035 7670698 163183..164679 1 NC_012442.1 FAD binding domain-containing protein 164679 7670698 BMEA_B0180 Brucella melitensis ATCC 23457 FAD binding domain-containing protein YP_002734007.1 163183 D 546272 CDS YP_002734008.1 225686036 7670699 164695..165927 1 NC_012442.1 FAD linked oxidase domain-containing protein 165927 7670699 BMEA_B0181 Brucella melitensis ATCC 23457 FAD linked oxidase domain-containing protein YP_002734008.1 164695 D 546272 CDS YP_002734009.1 225686037 7670700 165932..167221 1 NC_012442.1 hypothetical protein 167221 7670700 BMEA_B0182 Brucella melitensis ATCC 23457 hypothetical protein YP_002734009.1 165932 D 546272 CDS YP_002734010.1 225686038 7670701 complement(167444..168271) 1 NC_012442.1 2,5-diketo-D-gluconic acid reductase A 168271 7670701 BMEA_B0183 Brucella melitensis ATCC 23457 2,5-diketo-D-gluconic acid reductase A YP_002734010.1 167444 R 546272 CDS YP_002734011.1 225686039 7670702 complement(168547..169281) 1 NC_012442.1 ErfK/YbiS/YcfS/YnhG family protein 169281 7670702 BMEA_B0184 Brucella melitensis ATCC 23457 ErfK/YbiS/YcfS/YnhG family protein YP_002734011.1 168547 R 546272 CDS YP_002734012.1 225686040 7670703 169521..170177 1 NC_012442.1 DNA-3-methyladenine glycosylase I 170177 7670703 BMEA_B0185 Brucella melitensis ATCC 23457 DNA-3-methyladenine glycosylase I YP_002734012.1 169521 D 546272 CDS YP_002734013.1 225686041 7670704 170296..170913 1 NC_012442.1 Lysine exporter protein LYSE/YGGA 170913 7670704 BMEA_B0186 Brucella melitensis ATCC 23457 Lysine exporter protein LYSE/YGGA YP_002734013.1 170296 D 546272 CDS YP_002734014.1 225686042 7670705 171024..172532 1 NC_012442.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 172532 hisS 7670705 hisS Brucella melitensis ATCC 23457 histidyl-tRNA synthetase YP_002734014.1 171024 D 546272 CDS YP_002734015.1 225686043 7670706 172541..173671 1 NC_012442.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 173671 hisZ 7670706 hisZ Brucella melitensis ATCC 23457 ATP phosphoribosyltransferase regulatory subunit YP_002734015.1 172541 D 546272 CDS YP_002734016.1 225686044 7670707 173668..174363 1 NC_012442.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 174363 hisG 7670707 hisG Brucella melitensis ATCC 23457 ATP phosphoribosyltransferase catalytic subunit YP_002734016.1 173668 D 546272 CDS YP_002734017.1 225686045 7670708 complement(174436..175674) 1 NC_012442.1 glucose/galactose transporter 175674 gluP 7670708 gluP Brucella melitensis ATCC 23457 glucose/galactose transporter YP_002734017.1 174436 R 546272 CDS YP_002734018.1 225686046 7670709 complement(175960..176361) 1 NC_012442.1 DoxX family protein 176361 7670709 BMEA_B0191 Brucella melitensis ATCC 23457 DoxX family protein YP_002734018.1 175960 R 546272 CDS YP_002734019.1 225686047 7670710 complement(176464..177855) 1 NC_012442.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 177855 fumC 7670710 fumC Brucella melitensis ATCC 23457 fumarate hydratase YP_002734019.1 176464 R 546272 CDS YP_002734020.1 225686048 7670711 complement(178006..178293) 1 NC_012442.1 hypothetical protein 178293 7670711 BMEA_B0193 Brucella melitensis ATCC 23457 hypothetical protein YP_002734020.1 178006 R 546272 CDS YP_002734021.1 225686049 7670712 complement(178590..178796) 1 NC_012442.1 hypothetical protein 178796 7670712 BMEA_B0194 Brucella melitensis ATCC 23457 hypothetical protein YP_002734021.1 178590 R 546272 CDS YP_002734022.1 225686050 7670713 complement(178940..180580) 1 NC_012442.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 180580 groEL 7670713 groEL Brucella melitensis ATCC 23457 chaperonin GroEL YP_002734022.1 178940 R 546272 CDS YP_002734023.1 225686051 7670714 complement(180671..180967) 1 NC_012442.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 180967 groES 7670714 groES Brucella melitensis ATCC 23457 co-chaperonin GroES YP_002734023.1 180671 R 546272 CDS YP_002734024.1 225686052 7670715 181087..181227 1 NC_012442.1 hypothetical protein 181227 7670715 BMEA_B0197 Brucella melitensis ATCC 23457 hypothetical protein YP_002734024.1 181087 D 546272 CDS YP_002734025.1 225686053 7670716 complement(181280..181384) 1 NC_012442.1 hypothetical protein 181384 7670716 BMEA_B0198 Brucella melitensis ATCC 23457 hypothetical protein YP_002734025.1 181280 R 546272 CDS YP_002734026.1 225686054 7670717 181445..182296 1 NC_012442.1 HAD-superfamily hydrolase 182296 7670717 BMEA_B0199 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002734026.1 181445 D 546272 CDS YP_002734027.1 225686055 7670718 182384..183373 1 NC_012442.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 183373 ribF 7670718 ribF Brucella melitensis ATCC 23457 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002734027.1 182384 D 546272 CDS YP_002734028.1 225686056 7670719 183717..186635 1 NC_012442.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 186635 ileS 7670719 ileS Brucella melitensis ATCC 23457 isoleucyl-tRNA synthetase YP_002734028.1 183717 D 546272 CDS YP_002734029.1 225686057 7670720 186827..187498 1 NC_012442.1 hypothetical protein 187498 7670720 BMEA_B0202 Brucella melitensis ATCC 23457 hypothetical protein YP_002734029.1 186827 D 546272 CDS YP_002734030.1 225686058 7670721 187843..188403 1 NC_012442.1 cytochrome B561 188403 7670721 BMEA_B0203 Brucella melitensis ATCC 23457 cytochrome B561 YP_002734030.1 187843 D 546272 CDS YP_002734031.1 225686059 7670722 complement(188457..188930) 1 NC_012442.1 cytidine and deoxycytidylate deaminase family protein 188930 7670722 BMEA_B0204 Brucella melitensis ATCC 23457 cytidine and deoxycytidylate deaminase family protein YP_002734031.1 188457 R 546272 CDS YP_002734032.1 225686060 7670723 189020..190816 1 NC_012442.1 hypothetical protein 190816 7670723 BMEA_B0205 Brucella melitensis ATCC 23457 hypothetical protein YP_002734032.1 189020 D 546272 CDS YP_002734033.1 225686061 7670724 190797..191360 1 NC_012442.1 methyltransferase 191360 7670724 BMEA_B0207 Brucella melitensis ATCC 23457 methyltransferase YP_002734033.1 190797 D 546272 CDS YP_002734034.1 225686062 7670726 194366..195247 1 NC_012442.1 patatin 195247 7670726 BMEA_B0209 Brucella melitensis ATCC 23457 patatin YP_002734034.1 194366 D 546272 CDS YP_002734035.1 225686063 7670727 complement(195260..197167) 1 NC_012442.1 potassium efflux system protein 197167 7670727 BMEA_B0210 Brucella melitensis ATCC 23457 potassium efflux system protein YP_002734035.1 195260 R 546272 CDS YP_002734036.1 225686064 7670728 197306..198649 1 NC_012442.1 peptidase U62 modulator of DNA gyrase 198649 7670728 BMEA_B0211 Brucella melitensis ATCC 23457 peptidase U62 modulator of DNA gyrase YP_002734036.1 197306 D 546272 CDS YP_002734037.1 225686065 7670729 198636..199445 1 NC_012442.1 inositol monophosphatase 199445 7670729 BMEA_B0212 Brucella melitensis ATCC 23457 inositol monophosphatase YP_002734037.1 198636 D 546272 CDS YP_002734038.1 225686066 7670730 199484..199735 1 NC_012442.1 hypothetical protein 199735 7670730 BMEA_B0213 Brucella melitensis ATCC 23457 hypothetical protein YP_002734038.1 199484 D 546272 CDS YP_002734039.1 225686067 7670731 199766..200542 1 NC_012442.1 hypothetical protein 200542 7670731 BMEA_B0214 Brucella melitensis ATCC 23457 hypothetical protein YP_002734039.1 199766 D 546272 CDS YP_002734040.1 225686068 7670732 200539..201879 1 NC_012442.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 201879 7670732 BMEA_B0215 Brucella melitensis ATCC 23457 3-deoxy-D-manno-octulosonic-acid transferase YP_002734040.1 200539 D 546272 CDS YP_002734041.1 225686069 7670733 201882..202907 1 NC_012442.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 202907 lpxK 7670733 lpxK Brucella melitensis ATCC 23457 tetraacyldisaccharide 4'-kinase YP_002734041.1 201882 D 546272 CDS YP_002734042.1 225686070 7670734 complement(202921..203157) 1 NC_012442.1 hypothetical protein 203157 7670734 BMEA_B0217 Brucella melitensis ATCC 23457 hypothetical protein YP_002734042.1 202921 R 546272 CDS YP_002734043.1 225686071 7670735 complement(203255..205126) 1 NC_012442.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 205126 mutL 7670735 mutL Brucella melitensis ATCC 23457 DNA mismatch repair protein YP_002734043.1 203255 R 546272 CDS YP_002734044.1 225686072 7670737 complement(206690..207844) 1 NC_012442.1 acyl-CoA dehydrogenase 207844 7670737 BMEA_B0220 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase YP_002734044.1 206690 R 546272 CDS YP_002734045.1 225686073 7670738 complement(207901..208755) 1 NC_012442.1 putative transcriptional regulator 208755 7670738 BMEA_B0221 Brucella melitensis ATCC 23457 putative transcriptional regulator YP_002734045.1 207901 R 546272 CDS YP_002734046.1 225686074 7670739 209015..209776 1 NC_012442.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 209776 7670739 BMEA_B0222 Brucella melitensis ATCC 23457 enoyl-CoA hydratase YP_002734046.1 209015 D 546272 CDS YP_002734047.1 225686075 7670741 211522..212763 1 NC_012442.1 L-carnitine dehydrogenase 212763 7670741 BMEA_B0224 Brucella melitensis ATCC 23457 L-carnitine dehydrogenase YP_002734047.1 211522 D 546272 CDS YP_002734048.1 225686076 7670742 complement(212747..214021) 1 NC_012442.1 NADH oxidase 214021 7670742 BMEA_B0225 Brucella melitensis ATCC 23457 NADH oxidase YP_002734048.1 212747 R 546272 CDS YP_002734049.1 225686077 7670743 214107..214571 1 NC_012442.1 mercuric resistance operon regulatory protein 214571 7670743 BMEA_B0226 Brucella melitensis ATCC 23457 mercuric resistance operon regulatory protein YP_002734049.1 214107 D 546272 CDS YP_002734050.1 225686078 7670744 complement(214617..215324) 1 NC_012442.1 ThiJ/PfpI family protein 215324 7670744 BMEA_B0227 Brucella melitensis ATCC 23457 ThiJ/PfpI family protein YP_002734050.1 214617 R 546272 CDS YP_002734051.1 225686079 7670745 complement(215555..216895) 1 NC_012442.1 sensor histidine kinase 216895 7670745 BMEA_B0228 Brucella melitensis ATCC 23457 sensor histidine kinase YP_002734051.1 215555 R 546272 CDS YP_002734052.1 225686080 7670746 complement(216895..217572) 1 NC_012442.1 DNA-binding response regulator 217572 7670746 BMEA_B0229 Brucella melitensis ATCC 23457 DNA-binding response regulator YP_002734052.1 216895 R 546272 CDS YP_002734053.1 225686081 7670747 complement(217700..217864) 1 NC_012442.1 hypothetical protein 217864 7670747 BMEA_B0230 Brucella melitensis ATCC 23457 hypothetical protein YP_002734053.1 217700 R 546272 CDS YP_002734054.1 225686082 7670748 217836..218108 1 NC_012442.1 hypothetical protein 218108 7670748 BMEA_B0231 Brucella melitensis ATCC 23457 hypothetical protein YP_002734054.1 217836 D 546272 CDS YP_002734055.1 225686083 7670749 218276..218746 1 NC_012442.1 hypothetical protein 218746 7670749 BMEA_B0232 Brucella melitensis ATCC 23457 hypothetical protein YP_002734055.1 218276 D 546272 CDS YP_002734056.1 225686084 7670750 218757..220961 1 NC_012442.1 oxidoreductase FAD-binding 220961 7670750 BMEA_B0233 Brucella melitensis ATCC 23457 oxidoreductase FAD-binding YP_002734056.1 218757 D 546272 CDS YP_002734057.1 225686085 7670751 220942..221919 1 NC_012442.1 thiamine biosynthesis lipoprotein ApbE 221919 7670751 BMEA_B0234 Brucella melitensis ATCC 23457 thiamine biosynthesis lipoprotein ApbE YP_002734057.1 220942 D 546272 CDS YP_002734058.1 225686086 7670752 complement(221962..223137) 1 NC_012442.1 GAF/GGDEF domain-containing protein 223137 7670752 BMEA_B0235 Brucella melitensis ATCC 23457 GAF/GGDEF domain-containing protein YP_002734058.1 221962 R 546272 CDS YP_002734059.1 225686087 7670754 224287..224427 1 NC_012442.1 hypothetical protein 224427 7670754 BMEA_B0238 Brucella melitensis ATCC 23457 hypothetical protein YP_002734059.1 224287 D 546272 CDS YP_002734060.1 225686088 7670755 224527..225228 1 NC_012442.1 GntR family transcriptional regulator 225228 7670755 BMEA_B0239 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734060.1 224527 D 546272 CDS YP_002734061.1 225686089 7670756 225329..226291 1 NC_012442.1 dihydrodipicolinate synthetase 226291 7670756 BMEA_B0240 Brucella melitensis ATCC 23457 dihydrodipicolinate synthetase YP_002734061.1 225329 D 546272 CDS YP_002734062.1 225686090 7670757 complement(226354..227391) 1 NC_012442.1 malate/L-sulfolactate dehydrogenase 227391 7670757 BMEA_B0241 Brucella melitensis ATCC 23457 malate/L-sulfolactate dehydrogenase YP_002734062.1 226354 R 546272 CDS YP_002734063.1 225686091 7670758 complement(227510..227608) 1 NC_012442.1 hypothetical protein 227608 7670758 BMEA_B0242 Brucella melitensis ATCC 23457 hypothetical protein YP_002734063.1 227510 R 546272 CDS YP_002734064.1 225686092 7670759 227628..228896 1 NC_012442.1 hypothetical protein 228896 7670759 BMEA_B0243 Brucella melitensis ATCC 23457 hypothetical protein YP_002734064.1 227628 D 546272 CDS YP_002734065.1 225686093 7670761 complement(229434..229589) 1 NC_012442.1 hypothetical protein 229589 7670761 BMEA_B0245 Brucella melitensis ATCC 23457 hypothetical protein YP_002734065.1 229434 R 546272 CDS YP_002734066.1 225686094 7670762 229693..230262 1 NC_012442.1 cytochrome c oxidase subunit 3 230262 7670762 BMEA_B0247 Brucella melitensis ATCC 23457 cytochrome c oxidase subunit 3 YP_002734066.1 229693 D 546272 CDS YP_002734067.1 225686095 7670763 230270..230548 1 NC_012442.1 hypothetical protein 230548 7670763 BMEA_B0248 Brucella melitensis ATCC 23457 hypothetical protein YP_002734067.1 230270 D 546272 CDS YP_002734068.1 225686096 7670764 230708..231160 1 NC_012442.1 Nitric oxide reductase subunit C 231160 7670764 BMEA_B0249 Brucella melitensis ATCC 23457 Nitric oxide reductase subunit C YP_002734068.1 230708 D 546272 CDS YP_002734069.1 225686097 7670765 231186..232535 1 NC_012442.1 Nitric oxide reductase subunit B 232535 7670765 BMEA_B0250 Brucella melitensis ATCC 23457 Nitric oxide reductase subunit B YP_002734069.1 231186 D 546272 CDS YP_002734070.1 225686098 7670766 232626..233438 1 NC_012442.1 denitrification regulatory protein NirQ 233438 7670766 BMEA_B0251 Brucella melitensis ATCC 23457 denitrification regulatory protein NirQ YP_002734070.1 232626 D 546272 CDS YP_002734071.1 225686099 7670767 233450..235351 1 NC_012442.1 protein norD 235351 7670767 BMEA_B0252 Brucella melitensis ATCC 23457 protein norD YP_002734071.1 233450 D 546272 CDS YP_002734072.1 225686100 7670768 235464..235826 1 NC_012442.1 hypothetical protein 235826 7670768 BMEA_B0253 Brucella melitensis ATCC 23457 hypothetical protein YP_002734072.1 235464 D 546272 CDS YP_002734073.1 225686101 7670769 235862..237229 1 NC_012442.1 hypothetical protein 237229 7670769 BMEA_B0254 Brucella melitensis ATCC 23457 hypothetical protein YP_002734073.1 235862 D 546272 CDS YP_002734074.1 225686102 7670770 237226..237753 1 NC_012442.1 hypothetical protein 237753 7670770 BMEA_B0255 Brucella melitensis ATCC 23457 hypothetical protein YP_002734074.1 237226 D 546272 CDS YP_002734075.1 225686103 7670771 237760..238086 1 NC_012442.1 hypothetical protein 238086 7670771 BMEA_B0256 Brucella melitensis ATCC 23457 hypothetical protein YP_002734075.1 237760 D 546272 CDS YP_002734076.1 225686104 7670772 238210..239385 1 NC_012442.1 hypothetical protein 239385 7670772 BMEA_B0257 Brucella melitensis ATCC 23457 hypothetical protein YP_002734076.1 238210 D 546272 CDS YP_002734077.1 225686105 7670773 239382..239966 1 NC_012442.1 Isoprenylcysteine carboxyl methyltransferase 239966 7670773 BMEA_B0258 Brucella melitensis ATCC 23457 Isoprenylcysteine carboxyl methyltransferase YP_002734077.1 239382 D 546272 CDS YP_002734078.1 225686106 7670774 239917..240615 1 NC_012442.1 hypothetical protein 240615 7670774 BMEA_B0259 Brucella melitensis ATCC 23457 hypothetical protein YP_002734078.1 239917 D 546272 CDS YP_002734079.1 225686107 7670775 240691..240840 1 NC_012442.1 hypothetical protein 240840 7670775 BMEA_B0260 Brucella melitensis ATCC 23457 hypothetical protein YP_002734079.1 240691 D 546272 CDS YP_002734080.1 225686108 7670776 240971..242101 1 NC_012442.1 nitrite reductase, copper-containing 242101 nirK 7670776 nirK Brucella melitensis ATCC 23457 nitrite reductase, copper-containing YP_002734080.1 240971 D 546272 CDS YP_002734081.1 225686109 7670777 242235..243155 1 NC_012442.1 hypothetical protein 243155 7670777 BMEA_B0262 Brucella melitensis ATCC 23457 hypothetical protein YP_002734081.1 242235 D 546272 CDS YP_002734082.1 225686110 7670778 243256..243951 1 NC_012442.1 transcriptional activator protein fnrA 243951 7670778 BMEA_B0263 Brucella melitensis ATCC 23457 transcriptional activator protein fnrA YP_002734082.1 243256 D 546272 CDS YP_002734083.1 225686111 7670779 244034..245089 1 NC_012442.1 Ribitol operon repressor 245089 7670779 BMEA_B0264 Brucella melitensis ATCC 23457 Ribitol operon repressor YP_002734083.1 244034 D 546272 CDS YP_002734084.1 225686112 7670780 complement(245270..245491) 1 NC_012442.1 hypothetical protein 245491 7670780 BMEA_B0265 Brucella melitensis ATCC 23457 hypothetical protein YP_002734084.1 245270 R 546272 CDS YP_002734085.1 225686113 7670781 245490..246542 1 NC_012442.1 multiple sugar-binding periplasmic receptor chvE 246542 7670781 BMEA_B0266 Brucella melitensis ATCC 23457 multiple sugar-binding periplasmic receptor chvE YP_002734085.1 245490 D 546272 CDS YP_002734086.1 225686114 7670782 246847..247713 1 NC_012442.1 Ribose import ATP-binding protein rbsA 2 247713 7670782 BMEA_B0267 Brucella melitensis ATCC 23457 Ribose import ATP-binding protein rbsA 2 YP_002734086.1 246847 D 546272 CDS YP_002734087.1 225686115 7670783 247753..248949 1 NC_012442.1 inner-membrane translocator 248949 7670783 BMEA_B0268 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002734087.1 247753 D 546272 CDS YP_002734088.1 225686116 7670784 249237..249965 1 NC_012442.1 Ribitol 2-dehydrogenase 249965 7670784 BMEA_B0269 Brucella melitensis ATCC 23457 Ribitol 2-dehydrogenase YP_002734088.1 249237 D 546272 CDS YP_002734089.1 225686117 7670785 249978..251582 1 NC_012442.1 FGGY-family pentulose kinase 251582 7670785 BMEA_B0270 Brucella melitensis ATCC 23457 FGGY-family pentulose kinase YP_002734089.1 249978 D 546272 CDS YP_002734090.1 225686118 7670786 complement(251719..252384) 1 NC_012442.1 RES domain-containing protein 252384 7670786 BMEA_B0271 Brucella melitensis ATCC 23457 RES domain-containing protein YP_002734090.1 251719 R 546272 CDS YP_002734091.1 225686119 7670787 complement(252381..252857) 1 NC_012442.1 hypothetical protein 252857 7670787 BMEA_B0272 Brucella melitensis ATCC 23457 hypothetical protein YP_002734091.1 252381 R 546272 CDS YP_002734092.1 225686120 7670788 complement(253005..254912) 1 NC_012442.1 microcin-J25 export ATP-binding/permease mcjD 254912 7670788 BMEA_B0273 Brucella melitensis ATCC 23457 microcin-J25 export ATP-binding/permease mcjD YP_002734092.1 253005 R 546272 CDS YP_002734093.1 225686121 7670789 complement(255066..255224) 1 NC_012442.1 hypothetical protein 255224 7670789 BMEA_B0274 Brucella melitensis ATCC 23457 hypothetical protein YP_002734093.1 255066 R 546272 CDS YP_002734094.1 225686122 7670790 255406..257769 1 NC_012442.1 Regulatory protein nosR 257769 7670790 BMEA_B0275 Brucella melitensis ATCC 23457 Regulatory protein nosR YP_002734094.1 255406 D 546272 CDS YP_002734095.1 225686123 7670792 259715..261109 1 NC_012442.1 copper-binding periplasmic protein 261109 7670792 BMEA_B0277 Brucella melitensis ATCC 23457 copper-binding periplasmic protein YP_002734095.1 259715 D 546272 CDS YP_002734096.1 225686124 7670793 261147..262097 1 NC_012442.1 copper transport ATP-binding protein NosF 262097 7670793 BMEA_B0278 Brucella melitensis ATCC 23457 copper transport ATP-binding protein NosF YP_002734096.1 261147 D 546272 CDS YP_002734097.1 225686125 7670794 262094..262924 1 NC_012442.1 membrane protein NosY 262924 7670794 BMEA_B0279 Brucella melitensis ATCC 23457 membrane protein NosY YP_002734097.1 262094 D 546272 CDS YP_002734098.1 225686126 7670795 262921..263460 1 NC_012442.1 NosL family protein 263460 7670795 BMEA_B0280 Brucella melitensis ATCC 23457 NosL family protein YP_002734098.1 262921 D 546272 CDS YP_002734099.1 225686127 7670797 264577..265275 1 NC_012442.1 transcriptional regulator Crp/Fnr family protein 265275 7670797 BMEA_B0282 Brucella melitensis ATCC 23457 transcriptional regulator Crp/Fnr family protein YP_002734099.1 264577 D 546272 CDS YP_002734100.1 225686128 7670798 265256..265855 1 NC_012442.1 pseudoazurin 265855 7670798 BMEA_B0283 Brucella melitensis ATCC 23457 pseudoazurin YP_002734100.1 265256 D 546272 CDS YP_002734101.1 225686129 7670799 265906..267147 1 NC_012442.1 NnrS family protein 267147 7670799 BMEA_B0284 Brucella melitensis ATCC 23457 NnrS family protein YP_002734101.1 265906 D 546272 CDS YP_002734102.1 225686130 7670800 complement(267221..268261) 1 NC_012442.1 NMT1/THI5 like domain-containing protein 268261 7670800 BMEA_B0285 Brucella melitensis ATCC 23457 NMT1/THI5 like domain-containing protein YP_002734102.1 267221 R 546272 CDS YP_002734103.1 225686131 7670801 complement(268287..269078) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 269078 7670801 BMEA_B0286 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734103.1 268287 R 546272 CDS YP_002734104.1 225686132 7670803 269999..270250 1 NC_012442.1 hypothetical protein 270250 7670803 BMEA_B0288 Brucella melitensis ATCC 23457 hypothetical protein YP_002734104.1 269999 D 546272 CDS YP_002734105.1 225686133 7670804 complement(270156..270299) 1 NC_012442.1 hypothetical protein 270299 7670804 BMEA_B0289 Brucella melitensis ATCC 23457 hypothetical protein YP_002734105.1 270156 R 546272 CDS YP_002734106.1 225686134 7670805 complement(270348..271280) 1 NC_012442.1 peptidase U32 271280 7670805 BMEA_B0290 Brucella melitensis ATCC 23457 peptidase U32 YP_002734106.1 270348 R 546272 CDS YP_002734107.1 225686135 7670806 complement(271283..272260) 1 NC_012442.1 peptidase U32 272260 7670806 BMEA_B0291 Brucella melitensis ATCC 23457 peptidase U32 YP_002734107.1 271283 R 546272 CDS YP_002734108.1 225686136 7670807 complement(272251..272775) 1 NC_012442.1 hypothetical protein 272775 7670807 BMEA_B0292 Brucella melitensis ATCC 23457 hypothetical protein YP_002734108.1 272251 R 546272 CDS YP_002734109.1 225686137 7670808 272889..274226 1 NC_012442.1 UbiD family decarboxylase 274226 ubiD 7670808 ubiD Brucella melitensis ATCC 23457 UbiD family decarboxylase YP_002734109.1 272889 D 546272 CDS YP_002734110.1 225686138 7670809 274223..274813 1 NC_012442.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 274813 7670809 BMEA_B0294 Brucella melitensis ATCC 23457 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002734110.1 274223 D 546272 CDS YP_002734111.1 225686139 7670810 complement(274823..275359) 1 NC_012442.1 hypothetical protein 275359 7670810 BMEA_B0295 Brucella melitensis ATCC 23457 hypothetical protein YP_002734111.1 274823 R 546272 CDS YP_002734112.1 225686140 7670811 complement(275356..276291) 1 NC_012442.1 chaperone SurA 276291 7670811 BMEA_B0296 Brucella melitensis ATCC 23457 chaperone SurA YP_002734112.1 275356 R 546272 CDS YP_002734113.1 225686141 7670812 complement(276297..277022) 1 NC_012442.1 respiratory nitrate reductase subunit gamma 277022 narI 7670812 narI Brucella melitensis ATCC 23457 respiratory nitrate reductase subunit gamma YP_002734113.1 276297 R 546272 CDS YP_002734114.1 225686142 7670813 complement(277033..277740) 1 NC_012442.1 nitrate reductase molybdenum cofactor assembly chaperone 277740 narJ 7670813 narJ Brucella melitensis ATCC 23457 nitrate reductase molybdenum cofactor assembly chaperone YP_002734114.1 277033 R 546272 CDS YP_002734115.1 225686143 7670814 complement(277740..279278) 1 NC_012442.1 nitrate reductase subunit beta 279278 narH 7670814 narH Brucella melitensis ATCC 23457 nitrate reductase subunit beta YP_002734115.1 277740 R 546272 CDS YP_002734116.1 225686144 7670815 complement(279275..283039) 1 NC_012442.1 nitrate reductase subunit alpha 283039 7670815 BMEA_B0300 Brucella melitensis ATCC 23457 nitrate reductase subunit alpha YP_002734116.1 279275 R 546272 CDS YP_002734117.1 225686145 7670816 complement(282954..285758) 1 NC_012442.1 nitrite transporter 285758 narK 7670816 narK Brucella melitensis ATCC 23457 nitrite transporter YP_002734117.1 282954 R 546272 CDS YP_002734118.1 225686146 7670817 286048..286758 1 NC_012442.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrB 286758 ftrB 7670817 ftrB Brucella melitensis ATCC 23457 transcriptional activator FtrB YP_002734118.1 286048 D 546272 CDS YP_002734119.1 225686147 7670818 complement(286813..287829) 1 NC_012442.1 HTH-type transcriptional regulator RafR 287829 7670818 BMEA_B0303 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator RafR YP_002734119.1 286813 R 546272 CDS YP_002734120.1 225686148 7670819 288180..289445 1 NC_012442.1 family 1 extracellular solute-binding protein 289445 7670819 BMEA_B0304 Brucella melitensis ATCC 23457 family 1 extracellular solute-binding protein YP_002734120.1 288180 D 546272 CDS YP_002734121.1 225686149 7670820 289522..290499 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 290499 7670820 BMEA_B0305 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734121.1 289522 D 546272 CDS YP_002734122.1 225686150 7670821 290502..291314 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 291314 7670821 BMEA_B0306 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734122.1 290502 D 546272 CDS YP_002734123.1 225686151 7670822 291321..292322 1 NC_012442.1 ATP-binding transport protein SmoK 292322 7670822 BMEA_B0307 Brucella melitensis ATCC 23457 ATP-binding transport protein SmoK YP_002734123.1 291321 D 546272 CDS YP_002734124.1 225686152 7670823 292385..293170 1 NC_012442.1 hypothetical protein 293170 7670823 BMEA_B0308 Brucella melitensis ATCC 23457 hypothetical protein YP_002734124.1 292385 D 546272 CDS YP_002734125.1 225686153 7670824 293179..294225 1 NC_012442.1 oxidoreductase domain-containing protein 294225 7670824 BMEA_B0309 Brucella melitensis ATCC 23457 oxidoreductase domain-containing protein YP_002734125.1 293179 D 546272 CDS YP_002734126.1 225686154 7670827 complement(297025..297351) 1 NC_012442.1 hypothetical protein 297351 7670827 BMEA_B0313 Brucella melitensis ATCC 23457 hypothetical protein YP_002734126.1 297025 R 546272 CDS YP_002734127.1 225686155 7670828 297545..297766 1 NC_012442.1 glutaredoxin-like protein NrdH 297766 nrdH 7670828 nrdH Brucella melitensis ATCC 23457 glutaredoxin-like protein NrdH YP_002734127.1 297545 D 546272 CDS YP_002734128.1 225686156 7670829 297780..298187 1 NC_012442.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 298187 nrdI 7670829 nrdI Brucella melitensis ATCC 23457 ribonucleotide reductase stimulatory protein YP_002734128.1 297780 D 546272 CDS YP_002734129.1 225686157 7670830 298238..300379 1 NC_012442.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 300379 7670830 BMEA_B0316 Brucella melitensis ATCC 23457 ribonucleotide-diphosphate reductase subunit alpha YP_002734129.1 298238 D 546272 CDS YP_002734130.1 225686158 7670831 300394..301383 1 NC_012442.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 301383 nrdF 7670831 nrdF Brucella melitensis ATCC 23457 ribonucleotide-diphosphate reductase subunit beta YP_002734130.1 300394 D 546272 CDS YP_002734131.1 225686159 7670832 complement(301552..301776) 1 NC_012442.1 hypothetical protein 301776 7670832 BMEA_B0318 Brucella melitensis ATCC 23457 hypothetical protein YP_002734131.1 301552 R 546272 CDS YP_002734132.1 225686160 7670833 301987..302118 1 NC_012442.1 hypothetical protein 302118 7670833 BMEA_B0319 Brucella melitensis ATCC 23457 hypothetical protein YP_002734132.1 301987 D 546272 CDS YP_002734133.1 225686161 7670834 302248..303009 1 NC_012442.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 303009 minC 7670834 minC Brucella melitensis ATCC 23457 septum formation inhibitor YP_002734133.1 302248 D 546272 CDS YP_002734134.1 225686162 7670835 303037..303852 1 NC_012442.1 septum site-determining protein MinD 303852 minD 7670835 minD Brucella melitensis ATCC 23457 septum site-determining protein MinD YP_002734134.1 303037 D 546272 CDS YP_002734135.1 225686163 7670836 303849..304121 1 NC_012442.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 304121 minE 7670836 minE Brucella melitensis ATCC 23457 cell division topological specificity factor MinE YP_002734135.1 303849 D 546272 CDS YP_002734136.1 225686164 7670837 304165..304332 1 NC_012442.1 hypothetical protein 304332 7670837 BMEA_B0323 Brucella melitensis ATCC 23457 hypothetical protein YP_002734136.1 304165 D 546272 CDS YP_002734137.1 225686165 7670839 complement(304661..305053) 1 NC_012442.1 hypothetical protein 305053 7670839 BMEA_B0325 Brucella melitensis ATCC 23457 hypothetical protein YP_002734137.1 304661 R 546272 CDS YP_002734138.1 225686166 7670841 306547..307614 1 NC_012442.1 polyamine ABC transporter ATP-binding protein 307614 7670841 BMEA_B0327 Brucella melitensis ATCC 23457 polyamine ABC transporter ATP-binding protein YP_002734138.1 306547 D 546272 CDS YP_002734139.1 225686167 7670842 307548..308786 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 308786 7670842 BMEA_B0328 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734139.1 307548 D 546272 CDS YP_002734140.1 225686168 7670843 308789..309565 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 309565 7670843 BMEA_B0329 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734140.1 308789 D 546272 CDS YP_002734141.1 225686169 7670844 309877..310056 1 NC_012442.1 hypothetical protein 310056 7670844 BMEA_B0330 Brucella melitensis ATCC 23457 hypothetical protein YP_002734141.1 309877 D 546272 CDS YP_002734142.1 225686170 7670845 310053..310277 1 NC_012442.1 hypothetical protein 310277 7670845 BMEA_B0331 Brucella melitensis ATCC 23457 hypothetical protein YP_002734142.1 310053 D 546272 CDS YP_002734143.1 225686171 7670846 310514..311041 1 NC_012442.1 hypothetical protein 311041 7670846 BMEA_B0332 Brucella melitensis ATCC 23457 hypothetical protein YP_002734143.1 310514 D 546272 CDS YP_002734144.1 225686172 7670847 complement(311184..311684) 1 NC_012442.1 hypothetical protein 311684 7670847 BMEA_B0333 Brucella melitensis ATCC 23457 hypothetical protein YP_002734144.1 311184 R 546272 CDS YP_002734145.1 225686173 7670848 complement(311681..314905) 1 NC_012442.1 hydrophobe/amphiphile efflux-1 family protein 314905 7670848 BMEA_B0334 Brucella melitensis ATCC 23457 hydrophobe/amphiphile efflux-1 family protein YP_002734145.1 311681 R 546272 CDS YP_002734146.1 225686174 7670849 complement(314909..316132) 1 NC_012442.1 RND family efflux transporter MFP subunit 316132 7670849 BMEA_B0335 Brucella melitensis ATCC 23457 RND family efflux transporter MFP subunit YP_002734146.1 314909 R 546272 CDS YP_002734147.1 225686175 7670850 complement(316318..316851) 1 NC_012442.1 membrane protein 316851 7670850 BMEA_B0336 Brucella melitensis ATCC 23457 membrane protein YP_002734147.1 316318 R 546272 CDS YP_002734148.1 225686176 7670851 complement(316926..317099) 1 NC_012442.1 hypothetical protein 317099 7670851 BMEA_B0337 Brucella melitensis ATCC 23457 hypothetical protein YP_002734148.1 316926 R 546272 CDS YP_002734149.1 225686177 7670853 318874..320439 1 NC_012442.1 glutamate/gamma-aminobutyrate antiporter 320439 7670853 BMEA_B0339 Brucella melitensis ATCC 23457 glutamate/gamma-aminobutyrate antiporter YP_002734149.1 318874 D 546272 CDS YP_002734150.1 225686178 7670855 321575..321919 1 NC_012442.1 inactive form; acid-resistance protein 321919 7670855 BMEA_B0341 Brucella melitensis ATCC 23457 acid-resistance protein YP_002734150.1 321575 D 546272 CDS YP_002734151.1 225686179 7670856 322431..322682 1 NC_012442.1 hypothetical protein 322682 7670856 BMEA_B0342 Brucella melitensis ATCC 23457 hypothetical protein YP_002734151.1 322431 D 546272 CDS YP_002734152.1 225686180 7670857 complement(322759..324351) 1 NC_012442.1 EAL 324351 7670857 BMEA_B0343 Brucella melitensis ATCC 23457 EAL YP_002734152.1 322759 R 546272 CDS YP_002734153.1 225686181 7670858 complement(324646..324912) 1 NC_012442.1 hypothetical protein 324912 7670858 BMEA_B0344 Brucella melitensis ATCC 23457 hypothetical protein YP_002734153.1 324646 R 546272 CDS YP_002734154.1 225686182 7670860 complement(326148..327563) 1 NC_012442.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 327563 7670860 BMEA_B0346 Brucella melitensis ATCC 23457 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_002734154.1 326148 R 546272 CDS YP_002734155.1 225686183 7670861 complement(327560..328993) 1 NC_012442.1 phosphomannomutase 328993 7670861 BMEA_B0347 Brucella melitensis ATCC 23457 phosphomannomutase YP_002734155.1 327560 R 546272 CDS YP_002734156.1 225686184 7670862 complement(329113..330219) 1 NC_012442.1 peptidase S58 DmpA 330219 7670862 BMEA_B0348 Brucella melitensis ATCC 23457 peptidase S58 DmpA YP_002734156.1 329113 R 546272 CDS YP_002734157.1 225686185 7670863 complement(330243..331598) 1 NC_012442.1 chloride channel core protein 331598 7670863 BMEA_B0349 Brucella melitensis ATCC 23457 chloride channel core protein YP_002734157.1 330243 R 546272 CDS YP_002734158.1 225686186 7670864 complement(331657..331818) 1 NC_012442.1 hypothetical protein 331818 7670864 BMEA_B0350 Brucella melitensis ATCC 23457 hypothetical protein YP_002734158.1 331657 R 546272 CDS YP_002734159.1 225686187 7670865 331793..333286 1 NC_012442.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 333286 guaB 7670865 guaB Brucella melitensis ATCC 23457 inosine 5'-monophosphate dehydrogenase YP_002734159.1 331793 D 546272 CDS YP_002734160.1 225686188 7670866 complement(333446..334576) 1 NC_012442.1 cytochrome c class I 334576 7670866 BMEA_B0352 Brucella melitensis ATCC 23457 cytochrome c class I YP_002734160.1 333446 R 546272 CDS YP_002734161.1 225686189 7670867 complement(334633..335586) 1 NC_012442.1 LysR family transcriptional regulator 335586 7670867 BMEA_B0353 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002734161.1 334633 R 546272 CDS YP_002734162.1 225686190 7670868 335756..337255 1 NC_012442.1 catalase 337255 7670868 BMEA_B0354 Brucella melitensis ATCC 23457 catalase YP_002734162.1 335756 D 546272 CDS YP_002734163.1 225686191 7670869 337350..337559 1 NC_012442.1 hypothetical protein 337559 7670869 BMEA_B0355 Brucella melitensis ATCC 23457 hypothetical protein YP_002734163.1 337350 D 546272 CDS YP_002734164.1 225686192 7670872 339968..340423 1 NC_012442.1 hypothetical protein 340423 7670872 BMEA_B0358 Brucella melitensis ATCC 23457 hypothetical protein YP_002734164.1 339968 D 546272 CDS YP_002734165.1 225686193 7670873 340420..341052 1 NC_012442.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 341052 7670873 BMEA_B0359 Brucella melitensis ATCC 23457 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002734165.1 340420 D 546272 CDS YP_002734166.1 225686194 7670874 341161..342723 1 NC_012442.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 342723 guaA 7670874 guaA Brucella melitensis ATCC 23457 GMP synthase YP_002734166.1 341161 D 546272 CDS YP_002734167.1 225686195 7670875 342809..342994 1 NC_012442.1 hypothetical protein 342994 7670875 BMEA_B0361 Brucella melitensis ATCC 23457 hypothetical protein YP_002734167.1 342809 D 546272 CDS YP_002734168.1 225686196 7670876 343106..343654 1 NC_012442.1 hypothetical protein 343654 7670876 BMEA_B0362 Brucella melitensis ATCC 23457 hypothetical protein YP_002734168.1 343106 D 546272 CDS YP_002734169.1 225686197 7670877 343658..344056 1 NC_012442.1 hypothetical protein 344056 7670877 BMEA_B0363 Brucella melitensis ATCC 23457 hypothetical protein YP_002734169.1 343658 D 546272 CDS YP_002734170.1 225686198 7670878 344063..344899 1 NC_012442.1 Ferrous iron permease efeU 344899 7670878 BMEA_B0364 Brucella melitensis ATCC 23457 Ferrous iron permease efeU YP_002734170.1 344063 D 546272 CDS YP_002734171.1 225686199 7670879 344860..346293 1 NC_012442.1 hypothetical protein 346293 7670879 BMEA_B0365 Brucella melitensis ATCC 23457 hypothetical protein YP_002734171.1 344860 D 546272 CDS YP_002734172.1 225686200 7670880 complement(346551..348929) 1 NC_012442.1 putative phosphoketolase 348929 7670880 BMEA_B0366 Brucella melitensis ATCC 23457 putative phosphoketolase YP_002734172.1 346551 R 546272 CDS YP_002734173.1 225686201 7670881 complement(348950..350155) 1 NC_012442.1 Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase 350155 ackA 7670881 ackA Brucella melitensis ATCC 23457 acetate kinase YP_002734173.1 348950 R 546272 CDS YP_002734174.1 225686202 7670882 350394..350555 1 NC_012442.1 hypothetical protein 350555 7670882 BMEA_B0368 Brucella melitensis ATCC 23457 hypothetical protein YP_002734174.1 350394 D 546272 CDS YP_002734175.1 225686203 7670883 350598..351761 1 NC_012442.1 cytochrome P450 109 351761 7670883 BMEA_B0369 Brucella melitensis ATCC 23457 cytochrome P450 109 YP_002734175.1 350598 D 546272 CDS YP_002734176.1 225686204 7670884 complement(351832..352509) 1 NC_012442.1 GntR family transcriptional regulator 352509 7670884 BMEA_B0370 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734176.1 351832 R 546272 CDS YP_002734177.1 225686205 7670885 352567..352788 1 NC_012442.1 hypothetical protein 352788 7670885 BMEA_B0371 Brucella melitensis ATCC 23457 hypothetical protein YP_002734177.1 352567 D 546272 CDS YP_002734178.1 225686206 7670886 352781..353788 1 NC_012442.1 quinone oxidoreductase, PIG3 family protein 353788 7670886 BMEA_B0372 Brucella melitensis ATCC 23457 quinone oxidoreductase, PIG3 family protein YP_002734178.1 352781 D 546272 CDS YP_002734179.1 225686207 7670887 353872..355083 1 NC_012442.1 Leu/Ile/Val-binding protein family protein 355083 7670887 BMEA_B0373 Brucella melitensis ATCC 23457 Leu/Ile/Val-binding protein family protein YP_002734179.1 353872 D 546272 CDS YP_002734180.1 225686208 7670889 358549..359346 1 NC_012442.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 359346 fabG 7670889 fabG Brucella melitensis ATCC 23457 3-ketoacyl-ACP reductase YP_002734180.1 358549 D 546272 CDS YP_002734181.1 225686209 7670890 359351..360169 1 NC_012442.1 Shikimate dehydrogenase 360169 7670890 BMEA_B0376 Brucella melitensis ATCC 23457 Shikimate dehydrogenase YP_002734181.1 359351 D 546272 CDS YP_002734182.1 225686210 7670891 360174..361808 1 NC_012442.1 oxidoreductase, GMC family protein 361808 7670891 BMEA_B0377 Brucella melitensis ATCC 23457 oxidoreductase, GMC family protein YP_002734182.1 360174 D 546272 CDS YP_002734183.1 225686211 7670892 361833..363266 1 NC_012442.1 Succinate-semialdehyde dehydrogenase NAD(P)+ 363266 7670892 BMEA_B0378 Brucella melitensis ATCC 23457 Succinate-semialdehyde dehydrogenase NAD(P)+ YP_002734183.1 361833 D 546272 CDS YP_002734184.1 225686212 7670893 363358..364521 1 NC_012442.1 Leu/Ile/Val-binding protein family protein 364521 7670893 BMEA_B0379 Brucella melitensis ATCC 23457 Leu/Ile/Val-binding protein family protein YP_002734184.1 363358 D 546272 CDS YP_002734185.1 225686213 7670894 364584..365711 1 NC_012442.1 alcohol dehydrogenase 1 365711 7670894 BMEA_B0380 Brucella melitensis ATCC 23457 alcohol dehydrogenase 1 YP_002734185.1 364584 D 546272 CDS YP_002734186.1 225686214 7670896 complement(367961..368914) 1 NC_012442.1 oligopeptide ABC transporter ATP-binding protein 368914 7670896 BMEA_B0382 Brucella melitensis ATCC 23457 oligopeptide ABC transporter ATP-binding protein YP_002734186.1 367961 R 546272 CDS YP_002734187.1 225686215 7670897 complement(368911..369927) 1 NC_012442.1 peptide ABC transporter ATPase 369927 7670897 BMEA_B0383 Brucella melitensis ATCC 23457 peptide ABC transporter ATPase YP_002734187.1 368911 R 546272 CDS YP_002734188.1 225686216 7670898 complement(369938..370855) 1 NC_012442.1 Dihydrodipicolinate synthase 370855 7670898 BMEA_B0384 Brucella melitensis ATCC 23457 Dihydrodipicolinate synthase YP_002734188.1 369938 R 546272 CDS YP_002734189.1 225686217 7670899 complement(370875..371783) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 371783 7670899 BMEA_B0385 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734189.1 370875 R 546272 CDS YP_002734190.1 225686218 7670900 complement(371749..372708) 1 NC_012442.1 ABC transporter permease 372708 7670900 BMEA_B0386 Brucella melitensis ATCC 23457 ABC transporter permease YP_002734190.1 371749 R 546272 CDS YP_002734191.1 225686219 7670901 complement(372808..374391) 1 NC_012442.1 extracellular solute-binding protein 374391 7670901 BMEA_B0387 Brucella melitensis ATCC 23457 extracellular solute-binding protein YP_002734191.1 372808 R 546272 CDS YP_002734192.1 225686220 7670902 complement(374388..375116) 1 NC_012442.1 GntR family transcriptional regulator 375116 7670902 BMEA_B0388 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734192.1 374388 R 546272 CDS YP_002734193.1 225686221 7670903 375276..376853 1 NC_012442.1 N-acetylmannosamine-6-phosphate 2-epimerase 376853 7670903 BMEA_B0389 Brucella melitensis ATCC 23457 N-acetylmannosamine-6-phosphate 2-epimerase YP_002734193.1 375276 D 546272 CDS YP_002734194.1 225686222 7670904 376859..378043 1 NC_012442.1 N-acetylneuraminic acid mutarotase 378043 7670904 BMEA_B0390 Brucella melitensis ATCC 23457 N-acetylneuraminic acid mutarotase YP_002734194.1 376859 D 546272 CDS YP_002734195.1 225686223 7670905 378159..378419 1 NC_012442.1 hypothetical protein 378419 7670905 BMEA_B0391 Brucella melitensis ATCC 23457 hypothetical protein YP_002734195.1 378159 D 546272 CDS YP_002734196.1 225686224 7670906 complement(378420..379178) 1 NC_012442.1 transcriptional regulator Crp/Fnr family protein 379178 7670906 BMEA_B0392 Brucella melitensis ATCC 23457 transcriptional regulator Crp/Fnr family protein YP_002734196.1 378420 R 546272 CDS YP_002734197.1 225686225 7670907 379541..380308 1 NC_012442.1 two component transcriptional regulator, LuxR family protein 380308 7670907 BMEA_B0393 Brucella melitensis ATCC 23457 two component transcriptional regulator, LuxR family protein YP_002734197.1 379541 D 546272 CDS YP_002734198.1 225686226 7670908 380345..382534 1 NC_012442.1 lipopolysaccharide biosynthesis protein 382534 7670908 BMEA_B0394 Brucella melitensis ATCC 23457 lipopolysaccharide biosynthesis protein YP_002734198.1 380345 D 546272 CDS YP_002734199.1 225686227 7670909 382544..383791 1 NC_012442.1 plectin-1 383791 7670909 BMEA_B0395 Brucella melitensis ATCC 23457 plectin-1 YP_002734199.1 382544 D 546272 CDS YP_002734200.1 225686228 7670911 complement(384859..385929) 1 NC_012442.1 GDP-mannose 4,6-dehydratase 385929 gmd 7670911 gmd Brucella melitensis ATCC 23457 GDP-mannose 4,6-dehydratase YP_002734200.1 384859 R 546272 CDS YP_002734201.1 225686229 7670912 386103..387443 1 NC_012442.1 putative glycosyltransferase wbjE 387443 7670912 BMEA_B0398 Brucella melitensis ATCC 23457 putative glycosyltransferase wbjE YP_002734201.1 386103 D 546272 CDS YP_002734202.1 225686230 7670913 387464..388699 1 NC_012442.1 glycosyl transferase group 1 protein 388699 7670913 BMEA_B0399 Brucella melitensis ATCC 23457 glycosyl transferase group 1 protein YP_002734202.1 387464 D 546272 CDS YP_002734203.1 225686231 7670914 388696..389892 1 NC_012442.1 glycosyl transferase group 1 protein 389892 7670914 BMEA_B0400 Brucella melitensis ATCC 23457 glycosyl transferase group 1 protein YP_002734203.1 388696 D 546272 CDS YP_002734204.1 225686232 7670915 complement(389963..390685) 1 NC_012442.1 outer membrane protein Omp31 390685 7670915 BMEA_B0401 Brucella melitensis ATCC 23457 outer membrane protein Omp31 YP_002734204.1 389963 R 546272 CDS YP_002734205.1 225686233 7670916 complement(391082..391696) 1 NC_012442.1 chloramphenicol acetyltransferase 391696 7670916 BMEA_B0402 Brucella melitensis ATCC 23457 chloramphenicol acetyltransferase YP_002734205.1 391082 R 546272 CDS YP_002734206.1 225686234 7670917 complement(391708..392970) 1 NC_012442.1 hypothetical protein 392970 7670917 BMEA_B0403 Brucella melitensis ATCC 23457 hypothetical protein YP_002734206.1 391708 R 546272 CDS YP_002734207.1 225686235 7670918 complement(392967..393584) 1 NC_012442.1 hypothetical protein 393584 7670918 BMEA_B0404 Brucella melitensis ATCC 23457 hypothetical protein YP_002734207.1 392967 R 546272 CDS YP_002734208.1 225686236 7670919 complement(393581..394462) 1 NC_012442.1 Lipopolysaccharide core biosynthesis glycosyltransferase kdtX 394462 7670919 BMEA_B0405 Brucella melitensis ATCC 23457 Lipopolysaccharide core biosynthesis glycosyltransferase kdtX YP_002734208.1 393581 R 546272 CDS YP_002734209.1 225686237 7670920 complement(394459..395580) 1 NC_012442.1 phospho-N-acetylmuramoyl-pentapeptide- transferase 395580 7670920 BMEA_B0406 Brucella melitensis ATCC 23457 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002734209.1 394459 R 546272 CDS YP_002734210.1 225686238 7670921 complement(395684..395791) 1 NC_012442.1 hypothetical protein 395791 7670921 BMEA_B0407 Brucella melitensis ATCC 23457 hypothetical protein YP_002734210.1 395684 R 546272 CDS YP_002734211.1 225686239 7670922 395873..397366 1 NC_012442.1 polysaccharide biosynthesis protein 397366 7670922 BMEA_B0408 Brucella melitensis ATCC 23457 polysaccharide biosynthesis protein YP_002734211.1 395873 D 546272 CDS YP_002734212.1 225686240 7670923 complement(398351..399592) 1 NC_012442.1 polysaccharide pyruvyl transferase 399592 7670923 BMEA_B0410 Brucella melitensis ATCC 23457 polysaccharide pyruvyl transferase YP_002734212.1 398351 R 546272 CDS YP_002734213.1 225686241 7670925 401125..402486 1 NC_012442.1 catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; glutamate-1-semialdehyde 2,1-aminomutase 402486 7670925 BMEA_B0412 Brucella melitensis ATCC 23457 glutamate-1-semialdehyde 2,1-aminomutase YP_002734213.1 401125 D 546272 CDS YP_002734214.1 225686242 7670926 402465..403799 1 NC_012442.1 hypothetical protein 403799 7670926 BMEA_B0413 Brucella melitensis ATCC 23457 hypothetical protein YP_002734214.1 402465 D 546272 CDS YP_002734215.1 225686243 7670927 403920..404981 1 NC_012442.1 NAD-dependent epimerase/dehydratase 404981 7670927 BMEA_B0414 Brucella melitensis ATCC 23457 NAD-dependent epimerase/dehydratase YP_002734215.1 403920 D 546272 CDS YP_002734216.1 225686244 7670928 405020..406333 1 NC_012442.1 hypothetical protein 406333 7670928 BMEA_B0415 Brucella melitensis ATCC 23457 hypothetical protein YP_002734216.1 405020 D 546272 CDS YP_002734217.1 225686245 7670929 complement(406296..406787) 1 NC_012442.1 dTDP-4-dehydrorhamnose 3,5-epimerase 406787 7670929 BMEA_B0416 Brucella melitensis ATCC 23457 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002734217.1 406296 R 546272 CDS YP_002734218.1 225686246 7670930 407140..408441 1 NC_012442.1 C-methyltransferase 408441 7670930 BMEA_B0417 Brucella melitensis ATCC 23457 C-methyltransferase YP_002734218.1 407140 D 546272 CDS YP_002734219.1 225686247 7670931 408444..409253 1 NC_012442.1 glucose-1-phosphate cytidylyltransferase 409253 7670931 BMEA_B0418 Brucella melitensis ATCC 23457 glucose-1-phosphate cytidylyltransferase YP_002734219.1 408444 D 546272 CDS YP_002734220.1 225686248 7670932 409250..409906 1 NC_012442.1 LmbE family protein 409906 7670932 BMEA_B0419 Brucella melitensis ATCC 23457 LmbE family protein YP_002734220.1 409250 D 546272 CDS YP_002734221.1 225686249 7670933 409974..410105 1 NC_012442.1 hypothetical protein 410105 7670933 BMEA_B0420 Brucella melitensis ATCC 23457 hypothetical protein YP_002734221.1 409974 D 546272 CDS YP_002734222.1 225686250 7670934 complement(410102..411382) 1 NC_012442.1 uracil-xanthine permease 411382 7670934 BMEA_B0421 Brucella melitensis ATCC 23457 uracil-xanthine permease YP_002734222.1 410102 R 546272 CDS YP_002734223.1 225686251 7670937 414527..415414 1 NC_012442.1 HTH-type transcriptional regulator BudR 415414 7670937 BMEA_B0424 Brucella melitensis ATCC 23457 HTH-type transcriptional regulator BudR YP_002734223.1 414527 D 546272 CDS YP_002734224.1 225686252 7670938 415499..415939 1 NC_012442.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 415939 msrB 7670938 msrB Brucella melitensis ATCC 23457 methionine sulfoxide reductase B YP_002734224.1 415499 D 546272 CDS YP_002734225.1 225686253 7670939 complement(415924..417066) 1 NC_012442.1 acyl-CoA dehydrogenase 417066 7670939 BMEA_B0426 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase YP_002734225.1 415924 R 546272 CDS YP_002734226.1 225686254 7670940 complement(417066..418256) 1 NC_012442.1 acetyl-CoA acetyltransferase 418256 7670940 BMEA_B0427 Brucella melitensis ATCC 23457 acetyl-CoA acetyltransferase YP_002734226.1 417066 R 546272 CDS YP_002734227.1 225686255 7670941 complement(418325..419092) 1 NC_012442.1 3-hydroxyacyl-CoA dehydrogenase type-2 419092 7670941 BMEA_B0428 Brucella melitensis ATCC 23457 3-hydroxyacyl-CoA dehydrogenase type-2 YP_002734227.1 418325 R 546272 CDS YP_002734228.1 225686256 7670944 421932..422111 1 NC_012442.1 hypothetical protein 422111 7670944 BMEA_B0431 Brucella melitensis ATCC 23457 hypothetical protein YP_002734228.1 421932 D 546272 CDS YP_002734229.1 225686257 7670945 422108..423352 1 NC_012442.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 423352 7670945 BMEA_B0432 Brucella melitensis ATCC 23457 D-3-phosphoglycerate dehydrogenase YP_002734229.1 422108 D 546272 CDS YP_002734230.1 225686258 7670946 complement(423405..423899) 1 NC_012442.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 423899 def 7670946 def Brucella melitensis ATCC 23457 peptide deformylase YP_002734230.1 423405 R 546272 CDS YP_002734231.1 225686259 7670947 complement(424645..425586) 1 NC_012442.1 hypothetical protein 425586 7670947 BMEA_B0434 Brucella melitensis ATCC 23457 hypothetical protein YP_002734231.1 424645 R 546272 CDS YP_002734232.1 225686260 7670948 425899..426222 1 NC_012442.1 regulatory protein ArsR 426222 7670948 BMEA_B0435 Brucella melitensis ATCC 23457 regulatory protein ArsR YP_002734232.1 425899 D 546272 CDS YP_002734233.1 225686261 7670949 426219..426629 1 NC_012442.1 hypothetical protein 426629 7670949 BMEA_B0436 Brucella melitensis ATCC 23457 hypothetical protein YP_002734233.1 426219 D 546272 CDS YP_002734234.1 225686262 7670950 426626..427063 1 NC_012442.1 hypothetical protein 427063 7670950 BMEA_B0437 Brucella melitensis ATCC 23457 hypothetical protein YP_002734234.1 426626 D 546272 CDS YP_002734235.1 225686263 7670951 complement(427086..427793) 1 NC_012442.1 GntR family transcriptional regulator 427793 7670951 BMEA_B0438 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734235.1 427086 R 546272 CDS YP_002734236.1 225686264 7670952 428039..429097 1 NC_012442.1 hypothetical protein 429097 7670952 BMEA_B0439 Brucella melitensis ATCC 23457 hypothetical protein YP_002734236.1 428039 D 546272 CDS YP_002734237.1 225686265 7670953 429640..430359 1 NC_012442.1 TetR family transcriptional regulator 430359 7670953 BMEA_B0440 Brucella melitensis ATCC 23457 TetR family transcriptional regulator YP_002734237.1 429640 D 546272 CDS YP_002734238.1 225686266 7670954 430364..431308 1 NC_012442.1 secretion protein HlyD family protein 431308 7670954 BMEA_B0441 Brucella melitensis ATCC 23457 secretion protein HlyD family protein YP_002734238.1 430364 D 546272 CDS YP_002734239.1 225686267 7670955 431220..432239 1 NC_012442.1 ABC transporter 432239 7670955 BMEA_B0442 Brucella melitensis ATCC 23457 ABC transporter YP_002734239.1 431220 D 546272 CDS YP_002734240.1 225686268 7670956 432236..433375 1 NC_012442.1 ABC transporter 433375 7670956 BMEA_B0443 Brucella melitensis ATCC 23457 ABC transporter YP_002734240.1 432236 D 546272 CDS YP_002734241.1 225686269 7670957 433413..433811 1 NC_012442.1 cupin 2 conserved barrel domain-containing protein 433811 7670957 BMEA_B0444 Brucella melitensis ATCC 23457 cupin 2 conserved barrel domain-containing protein YP_002734241.1 433413 D 546272 CDS YP_002734242.1 225686270 7670958 complement(433818..434636) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 434636 7670958 BMEA_B0445 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734242.1 433818 R 546272 CDS YP_002734243.1 225686271 7670959 complement(434629..435396) 1 NC_012442.1 ABC transporter 435396 7670959 BMEA_B0446 Brucella melitensis ATCC 23457 ABC transporter YP_002734243.1 434629 R 546272 CDS YP_002734244.1 225686272 7670960 complement(435442..436464) 1 NC_012442.1 NMT1/THI5 like domain-containing protein 436464 7670960 BMEA_B0447 Brucella melitensis ATCC 23457 NMT1/THI5 like domain-containing protein YP_002734244.1 435442 R 546272 CDS YP_002734245.1 225686273 7670961 436811..437299 1 NC_012442.1 transcriptional regulator slyA 437299 7670961 BMEA_B0448 Brucella melitensis ATCC 23457 transcriptional regulator slyA YP_002734245.1 436811 D 546272 CDS YP_002734246.1 225686274 7670963 438946..439995 1 NC_012442.1 secretion protein HlyD family protein 439995 7670963 BMEA_B0450 Brucella melitensis ATCC 23457 secretion protein HlyD family protein YP_002734246.1 438946 D 546272 CDS YP_002734247.1 225686275 7670964 complement(440067..441491) 1 NC_012442.1 two-component sensor histidine kinase 441491 7670964 BMEA_B0451 Brucella melitensis ATCC 23457 two-component sensor histidine kinase YP_002734247.1 440067 R 546272 CDS YP_002734248.1 225686276 7670965 complement(441488..442204) 1 NC_012442.1 putative transcriptional regulator ycf27 442204 7670965 BMEA_B0452 Brucella melitensis ATCC 23457 putative transcriptional regulator ycf27 YP_002734248.1 441488 R 546272 CDS YP_002734249.1 225686277 7670966 442528..442893 1 NC_012442.1 hypothetical protein 442893 7670966 BMEA_B0454 Brucella melitensis ATCC 23457 hypothetical protein YP_002734249.1 442528 D 546272 CDS YP_002734250.1 225686278 7670967 442890..443123 1 NC_012442.1 hypothetical protein 443123 7670967 BMEA_B0455 Brucella melitensis ATCC 23457 hypothetical protein YP_002734250.1 442890 D 546272 CDS YP_002734251.1 225686279 7670968 443318..443668 1 NC_012442.1 hypothetical protein 443668 7670968 BMEA_B0456 Brucella melitensis ATCC 23457 hypothetical protein YP_002734251.1 443318 D 546272 CDS YP_002734252.1 225686280 7670969 complement(443791..445065) 1 NC_012442.1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase 445065 7670969 BMEA_B0457 Brucella melitensis ATCC 23457 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_002734252.1 443791 R 546272 CDS YP_002734253.1 225686281 7670970 complement(445148..445597) 1 NC_012442.1 transcriptional regulator hosA 445597 7670970 BMEA_B0458 Brucella melitensis ATCC 23457 transcriptional regulator hosA YP_002734253.1 445148 R 546272 CDS YP_002734254.1 225686282 7670971 445879..446658 1 NC_012442.1 glyoxalase/bleomycin resistance protein/dioxygenase 446658 7670971 BMEA_B0459 Brucella melitensis ATCC 23457 glyoxalase/bleomycin resistance protein/dioxygenase YP_002734254.1 445879 D 546272 CDS YP_002734255.1 225686283 7670972 complement(446722..446892) 1 NC_012442.1 hypothetical protein 446892 7670972 BMEA_B0460 Brucella melitensis ATCC 23457 hypothetical protein YP_002734255.1 446722 R 546272 CDS YP_002734256.1 225686284 7670973 complement(446939..448372) 1 NC_012442.1 amino acid carrier protein 448372 agcS 7670973 agcS Brucella melitensis ATCC 23457 amino acid carrier protein YP_002734256.1 446939 R 546272 CDS YP_002734257.1 225686285 7670975 complement(449366..450286) 1 NC_012442.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 450286 metA 7670975 metA Brucella melitensis ATCC 23457 homoserine O-succinyltransferase YP_002734257.1 449366 R 546272 CDS YP_002734258.1 225686286 7670976 450401..450901 1 NC_012442.1 hypothetical protein 450901 7670976 BMEA_B0464 Brucella melitensis ATCC 23457 hypothetical protein YP_002734258.1 450401 D 546272 CDS YP_002734259.1 225686287 7670977 complement(451130..452110) 1 NC_012442.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 452110 7670977 BMEA_B0465 Brucella melitensis ATCC 23457 3-oxoacyl-(acyl carrier protein) synthase II YP_002734259.1 451130 R 546272 CDS YP_002734260.1 225686288 7670978 complement(452107..453381) 1 NC_012442.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 453381 bioA 7670978 bioA Brucella melitensis ATCC 23457 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_002734260.1 452107 R 546272 CDS YP_002734261.1 225686289 7670979 complement(453378..454016) 1 NC_012442.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 454016 bioD 7670979 bioD Brucella melitensis ATCC 23457 dithiobiotin synthetase YP_002734261.1 453378 R 546272 CDS YP_002734262.1 225686290 7670980 complement(454013..455149) 1 NC_012442.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 455149 7670980 BMEA_B0468 Brucella melitensis ATCC 23457 8-amino-7-oxononanoate synthase YP_002734262.1 454013 R 546272 CDS YP_002734263.1 225686291 7670981 complement(455146..456186) 1 NC_012442.1 biotin synthase 456186 bioB 7670981 bioB Brucella melitensis ATCC 23457 biotin synthase YP_002734263.1 455146 R 546272 CDS YP_002734264.1 225686292 7670982 456425..456565 1 NC_012442.1 hypothetical protein 456565 7670982 BMEA_B0470 Brucella melitensis ATCC 23457 hypothetical protein YP_002734264.1 456425 D 546272 CDS YP_002734265.1 225686293 7670983 complement(456543..456824) 1 NC_012442.1 hypothetical protein 456824 7670983 BMEA_B0471 Brucella melitensis ATCC 23457 hypothetical protein YP_002734265.1 456543 R 546272 CDS YP_002734266.1 225686294 7670984 457087..457605 1 NC_012442.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 457605 mogA 7670984 mogA Brucella melitensis ATCC 23457 molybdenum cofactor biosynthesis protein MogA YP_002734266.1 457087 D 546272 CDS YP_002734267.1 225686295 7670985 complement(457657..458256) 1 NC_012442.1 hypothetical protein 458256 7670985 BMEA_B0473 Brucella melitensis ATCC 23457 hypothetical protein YP_002734267.1 457657 R 546272 CDS YP_002734268.1 225686296 7670987 460349..463267 1 NC_012442.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; putative monovalent cation/H+ antiporter subunit A 463267 7670987 BMEA_B0475 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit A YP_002734268.1 460349 D 546272 CDS YP_002734269.1 225686297 7670988 463267..463605 1 NC_012442.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 463605 7670988 BMEA_B0476 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit C YP_002734269.1 463267 D 546272 CDS YP_002734270.1 225686298 7670989 463608..465236 1 NC_012442.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 465236 7670989 BMEA_B0477 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit D YP_002734270.1 463608 D 546272 CDS YP_002734271.1 225686299 7670990 465233..465748 1 NC_012442.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 465748 7670990 BMEA_B0478 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit E YP_002734271.1 465233 D 546272 CDS YP_002734272.1 225686300 7670991 465745..466026 1 NC_012442.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 466026 7670991 BMEA_B0479 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit F YP_002734272.1 465745 D 546272 CDS YP_002734273.1 225686301 7670992 466023..466385 1 NC_012442.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit G 466385 7670992 BMEA_B0480 Brucella melitensis ATCC 23457 putative monovalent cation/H+ antiporter subunit G YP_002734273.1 466023 D 546272 CDS YP_002734274.1 225686302 7670993 466810..467346 1 NC_012442.1 hypothetical protein 467346 7670993 BMEA_B0481 Brucella melitensis ATCC 23457 hypothetical protein YP_002734274.1 466810 D 546272 CDS YP_002734275.1 225686303 7670994 467454..469079 1 NC_012442.1 cysteine ABC transporter permease/ATP-binding protein CydC 469079 cydD 7670994 cydD Brucella melitensis ATCC 23457 cysteine ABC transporter permease/ATP-binding protein CydC YP_002734275.1 467454 D 546272 CDS YP_002734276.1 225686304 7670995 469076..470746 1 NC_012442.1 cysteine ABC transporter permease/ATP-binding protein CydC 470746 7670995 BMEA_B0483 Brucella melitensis ATCC 23457 cysteine ABC transporter permease/ATP-binding protein CydC YP_002734276.1 469076 D 546272 CDS YP_002734277.1 225686305 7670996 470889..472466 1 NC_012442.1 cytochrome d ubiquinol oxidase subunit 1 472466 7670996 BMEA_B0484 Brucella melitensis ATCC 23457 cytochrome d ubiquinol oxidase subunit 1 YP_002734277.1 470889 D 546272 CDS YP_002734278.1 225686306 7670997 472472..473626 1 NC_012442.1 cytochrome d ubiquinol oxidase subunit II 473626 cydB 7670997 cydB Brucella melitensis ATCC 23457 cytochrome d ubiquinol oxidase subunit II YP_002734278.1 472472 D 546272 CDS YP_002734279.1 225686307 7670998 473604..473798 1 NC_012442.1 cyd operon protein YbgT 473798 7670998 BMEA_B0486 Brucella melitensis ATCC 23457 cyd operon protein YbgT YP_002734279.1 473604 D 546272 CDS YP_002734280.1 225686308 7670999 complement(473849..474622) 1 NC_012442.1 GntR family transcriptional regulator 474622 7670999 BMEA_B0487 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734280.1 473849 R 546272 CDS YP_002734281.1 225686309 7671000 complement(474619..475506) 1 NC_012442.1 BadF/BadG/BcrA/BcrD type ATPase 475506 7671000 BMEA_B0488 Brucella melitensis ATCC 23457 BadF/BadG/BcrA/BcrD type ATPase YP_002734281.1 474619 R 546272 CDS YP_002734282.1 225686310 7671001 475670..475858 1 NC_012442.1 hypothetical protein 475858 7671001 BMEA_B0489 Brucella melitensis ATCC 23457 hypothetical protein YP_002734282.1 475670 D 546272 CDS YP_002734283.1 225686311 7671003 477412..478431 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 478431 7671003 BMEA_B0492 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734283.1 477412 D 546272 CDS YP_002734284.1 225686312 7671004 478444..479283 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 479283 7671004 BMEA_B0493 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734284.1 478444 D 546272 CDS YP_002734285.1 225686313 7671005 479280..480350 1 NC_012442.1 oxidoreductase domain-containing protein 480350 7671005 BMEA_B0494 Brucella melitensis ATCC 23457 oxidoreductase domain-containing protein YP_002734285.1 479280 D 546272 CDS YP_002734286.1 225686314 7671006 480380..481381 1 NC_012442.1 ATP-binding transport protein SmoK 481381 7671006 BMEA_B0495 Brucella melitensis ATCC 23457 ATP-binding transport protein SmoK YP_002734286.1 480380 D 546272 CDS YP_002734287.1 225686315 7671007 481434..481685 1 NC_012442.1 hypothetical protein 481685 7671007 BMEA_B0496 Brucella melitensis ATCC 23457 hypothetical protein YP_002734287.1 481434 D 546272 CDS YP_002734288.1 225686316 7671008 481982..483214 1 NC_012442.1 2-oxoisovalerate dehydrogenase subunit alpha 483214 7671008 BMEA_B0497 Brucella melitensis ATCC 23457 2-oxoisovalerate dehydrogenase subunit alpha YP_002734288.1 481982 D 546272 CDS YP_002734289.1 225686317 7671009 483318..484331 1 NC_012442.1 2-oxoisovalerate dehydrogenase subunit beta 484331 7671009 BMEA_B0498 Brucella melitensis ATCC 23457 2-oxoisovalerate dehydrogenase subunit beta YP_002734289.1 483318 D 546272 CDS YP_002734290.1 225686318 7671010 484332..485627 1 NC_012442.1 branched-chain alpha-keto acid dehydrogenase subunit E2 485627 7671010 BMEA_B0499 Brucella melitensis ATCC 23457 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002734290.1 484332 D 546272 CDS YP_002734291.1 225686319 7671011 485725..487026 1 NC_012442.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 487026 lpdA 7671011 lpdA Brucella melitensis ATCC 23457 dihydrolipoamide dehydrogenase YP_002734291.1 485725 D 546272 CDS YP_002734292.1 225686320 7671012 complement(487015..487776) 1 NC_012442.1 Surfeit locus 1 family protein 487776 7671012 BMEA_B0501 Brucella melitensis ATCC 23457 Surfeit locus 1 family protein YP_002734292.1 487015 R 546272 CDS YP_002734293.1 225686321 7671013 488035..488289 1 NC_012442.1 hypothetical protein 488289 7671013 BMEA_B0503 Brucella melitensis ATCC 23457 hypothetical protein YP_002734293.1 488035 D 546272 CDS YP_002734294.1 225686322 7671014 complement(488470..490935) 1 NC_012442.1 DNA translocase ftsK 490935 7671014 BMEA_B0504 Brucella melitensis ATCC 23457 DNA translocase ftsK YP_002734294.1 488470 R 546272 CDS YP_002734295.1 225686323 7671015 complement(491230..492252) 1 NC_012442.1 peptidase S58 DmpA 492252 7671015 BMEA_B0505 Brucella melitensis ATCC 23457 peptidase S58 DmpA YP_002734295.1 491230 R 546272 CDS YP_002734296.1 225686324 7671016 492499..493809 1 NC_012442.1 major facilitator superfamily protein 493809 7671016 BMEA_B0506 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002734296.1 492499 D 546272 CDS YP_002734297.1 225686325 7671017 complement(493968..494606) 1 NC_012442.1 alkylated DNA repair protein AlkB 494606 7671017 BMEA_B0507 Brucella melitensis ATCC 23457 alkylated DNA repair protein AlkB YP_002734297.1 493968 R 546272 CDS YP_002734298.1 225686326 7671018 complement(494688..496298) 1 NC_012442.1 ABC transporter 496298 7671018 BMEA_B0508 Brucella melitensis ATCC 23457 ABC transporter YP_002734298.1 494688 R 546272 CDS YP_002734299.1 225686327 7671019 complement(496300..497433) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 497433 7671019 BMEA_B0509 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734299.1 496300 R 546272 CDS YP_002734300.1 225686328 7671020 complement(497426..498349) 1 NC_012442.1 hypothetical protein 498349 7671020 BMEA_B0510 Brucella melitensis ATCC 23457 hypothetical protein YP_002734300.1 497426 R 546272 CDS YP_002734301.1 225686329 7671021 complement(498564..500141) 1 NC_012442.1 oligopeptide-binding protein oppA 500141 7671021 BMEA_B0511 Brucella melitensis ATCC 23457 oligopeptide-binding protein oppA YP_002734301.1 498564 R 546272 CDS YP_002734302.1 225686330 7671022 complement(500252..501829) 1 NC_012442.1 oligopeptide-binding protein oppA 501829 7671022 BMEA_B0512 Brucella melitensis ATCC 23457 oligopeptide-binding protein oppA YP_002734302.1 500252 R 546272 CDS YP_002734303.1 225686331 7671023 complement(501923..502093) 1 NC_012442.1 hypothetical protein 502093 7671023 BMEA_B0513 Brucella melitensis ATCC 23457 hypothetical protein YP_002734303.1 501923 R 546272 CDS YP_002734304.1 225686332 7671024 complement(502256..502603) 1 NC_012442.1 hypothetical protein 502603 7671024 BMEA_B0514 Brucella melitensis ATCC 23457 hypothetical protein YP_002734304.1 502256 R 546272 CDS YP_002734305.1 225686333 7671025 502845..503441 1 NC_012442.1 NAD-dependent epimerase/dehydratase 503441 7671025 BMEA_B0515 Brucella melitensis ATCC 23457 NAD-dependent epimerase/dehydratase YP_002734305.1 502845 D 546272 CDS YP_002734306.1 225686334 7671026 503441..504427 1 NC_012442.1 UDP-glucose 4-epimerase 504427 galE 7671026 galE Brucella melitensis ATCC 23457 UDP-glucose 4-epimerase YP_002734306.1 503441 D 546272 CDS YP_002734307.1 225686335 7671028 506275..507699 1 NC_012442.1 nucleotide sugar dehydrogenase 507699 7671028 BMEA_B0518 Brucella melitensis ATCC 23457 nucleotide sugar dehydrogenase YP_002734307.1 506275 D 546272 CDS YP_002734308.1 225686336 7671029 507689..508234 1 NC_012442.1 hypothetical protein 508234 7671029 BMEA_B0519 Brucella melitensis ATCC 23457 hypothetical protein YP_002734308.1 507689 D 546272 CDS YP_002734309.1 225686337 7671030 508284..509228 1 NC_012442.1 mannan endo-1,4-beta-mannosidase A and B 509228 7671030 BMEA_B0520 Brucella melitensis ATCC 23457 mannan endo-1,4-beta-mannosidase A and B YP_002734309.1 508284 D 546272 CDS YP_002734310.1 225686338 7671031 509348..509842 1 NC_012442.1 hypothetical protein 509842 7671031 BMEA_B0521 Brucella melitensis ATCC 23457 hypothetical protein YP_002734310.1 509348 D 546272 CDS YP_002734311.1 225686339 7671032 complement(509959..510285) 1 NC_012442.1 hypothetical protein 510285 7671032 BMEA_B0522 Brucella melitensis ATCC 23457 hypothetical protein YP_002734311.1 509959 R 546272 CDS YP_002734312.1 225686340 7671034 complement(512023..512667) 1 NC_012442.1 hypothetical protein 512667 7671034 BMEA_B0524 Brucella melitensis ATCC 23457 hypothetical protein YP_002734312.1 512023 R 546272 CDS YP_002734313.1 225686341 7671035 complement(512642..514666) 1 NC_012442.1 glycoprotein X 514666 7671035 BMEA_B0525 Brucella melitensis ATCC 23457 glycoprotein X YP_002734313.1 512642 R 546272 CDS YP_002734314.1 225686342 7671036 complement(515242..515847) 1 NC_012442.1 yecA family protein 515847 7671036 BMEA_B0527 Brucella melitensis ATCC 23457 yecA family protein YP_002734314.1 515242 R 546272 CDS YP_002734315.1 225686343 7671037 complement(515844..517415) 1 NC_012442.1 transposase IS66 517415 7671037 BMEA_B0528 Brucella melitensis ATCC 23457 transposase IS66 YP_002734315.1 515844 R 546272 CDS YP_002734316.1 225686344 7671038 complement(517465..517851) 1 NC_012442.1 IS66 family element 517851 7671038 BMEA_B0529 Brucella melitensis ATCC 23457 IS66 family element YP_002734316.1 517465 R 546272 CDS YP_002734317.1 225686345 7671039 complement(517815..518282) 1 NC_012442.1 transposase IS3/IS911 family protein 518282 7671039 BMEA_B0530 Brucella melitensis ATCC 23457 transposase IS3/IS911 family protein YP_002734317.1 517815 R 546272 CDS YP_002734318.1 225686346 7671040 complement(518363..518725) 1 NC_012442.1 ISBm1, transposase orfA 518725 7671040 BMEA_B0531 Brucella melitensis ATCC 23457 ISBm1, transposase orfA YP_002734318.1 518363 R 546272 CDS YP_002734319.1 225686347 7671041 519491..519898 1 NC_012442.1 hypothetical protein 519898 7671041 BMEA_B0532 Brucella melitensis ATCC 23457 hypothetical protein YP_002734319.1 519491 D 546272 CDS YP_002734320.1 225686348 7671043 520371..520829 1 NC_012442.1 YbaK/prolyl-tRNA synthetase associated protein 520829 7671043 BMEA_B0534 Brucella melitensis ATCC 23457 YbaK/prolyl-tRNA synthetase associated protein YP_002734320.1 520371 D 546272 CDS YP_002734321.1 225686349 7671044 521075..521536 1 NC_012442.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 521536 rirA 7671044 rirA Brucella melitensis ATCC 23457 iron-responsive transcriptional regulator YP_002734321.1 521075 D 546272 CDS YP_002734322.1 225686350 7671045 521653..521967 1 NC_012442.1 antibiotic biosynthesis monooxygenase 521967 7671045 BMEA_B0536 Brucella melitensis ATCC 23457 antibiotic biosynthesis monooxygenase YP_002734322.1 521653 D 546272 CDS YP_002734323.1 225686351 7671046 522423..522734 1 NC_012442.1 hypothetical protein 522734 7671046 BMEA_B0537 Brucella melitensis ATCC 23457 hypothetical protein YP_002734323.1 522423 D 546272 CDS YP_002734324.1 225686352 7671047 522700..523185 1 NC_012442.1 bacterioferritin 523185 bfr 7671047 bfr Brucella melitensis ATCC 23457 bacterioferritin YP_002734324.1 522700 D 546272 CDS YP_002734325.1 225686353 7671048 523349..524662 1 NC_012442.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 524662 rimO 7671048 rimO Brucella melitensis ATCC 23457 ribosomal protein S12 methylthiotransferase YP_002734325.1 523349 D 546272 CDS YP_002734326.1 225686354 7671049 complement(524802..525869) 1 NC_012442.1 basic membrane lipoprotein 525869 7671049 BMEA_B0540 Brucella melitensis ATCC 23457 basic membrane lipoprotein YP_002734326.1 524802 R 546272 CDS YP_002734327.1 225686355 7671050 complement(525952..526872) 1 NC_012442.1 inner-membrane translocator 526872 7671050 BMEA_B0541 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002734327.1 525952 R 546272 CDS YP_002734328.1 225686356 7671052 complement(527958..529520) 1 NC_012442.1 ABC transporter 529520 7671052 BMEA_B0543 Brucella melitensis ATCC 23457 ABC transporter YP_002734328.1 527958 R 546272 CDS YP_002734329.1 225686357 7671054 complement(530595..531395) 1 NC_012442.1 phosphatidylcholine synthase 531395 7671054 BMEA_B0545 Brucella melitensis ATCC 23457 phosphatidylcholine synthase YP_002734329.1 530595 R 546272 CDS YP_002734330.1 225686358 7671055 531611..532969 1 NC_012442.1 2-octaprenyl-6-methoxyphenyl hydroxylase 532969 7671055 BMEA_B0546 Brucella melitensis ATCC 23457 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002734330.1 531611 D 546272 CDS YP_002734331.1 225686359 7671056 533042..533380 1 NC_012442.1 hemimethylated DNA binding domain-containing protein 533380 7671056 BMEA_B0547 Brucella melitensis ATCC 23457 hemimethylated DNA binding domain-containing protein YP_002734331.1 533042 D 546272 CDS YP_002734332.1 225686360 7671057 complement(533513..534130) 1 NC_012442.1 hypothetical protein 534130 7671057 BMEA_B0548 Brucella melitensis ATCC 23457 hypothetical protein YP_002734332.1 533513 R 546272 CDS YP_002734333.1 225686361 7671058 534475..536322 1 NC_012442.1 family 5 extracellular solute-binding protein 536322 7671058 BMEA_B0549 Brucella melitensis ATCC 23457 family 5 extracellular solute-binding protein YP_002734333.1 534475 D 546272 CDS YP_002734334.1 225686362 7671059 536394..536504 1 NC_012442.1 hypothetical protein 536504 7671059 BMEA_B0550 Brucella melitensis ATCC 23457 hypothetical protein YP_002734334.1 536394 D 546272 CDS YP_002734335.1 225686363 7671060 536501..537175 1 NC_012442.1 DSBA oxidoreductase 537175 7671060 BMEA_B0551 Brucella melitensis ATCC 23457 DSBA oxidoreductase YP_002734335.1 536501 D 546272 CDS YP_002734336.1 225686364 7671061 complement(537353..537751) 1 NC_012442.1 metallothiol transferase FosB 537751 7671061 BMEA_B0552 Brucella melitensis ATCC 23457 metallothiol transferase FosB YP_002734336.1 537353 R 546272 CDS YP_002734337.1 225686365 7671062 complement(537844..541356) 1 NC_012442.1 transcription-repair coupling factor 541356 mfd 7671062 mfd Brucella melitensis ATCC 23457 transcription-repair coupling factor YP_002734337.1 537844 R 546272 CDS YP_002734338.1 225686366 7671063 complement(541367..541654) 1 NC_012442.1 hypothetical protein 541654 7671063 BMEA_B0554 Brucella melitensis ATCC 23457 hypothetical protein YP_002734338.1 541367 R 546272 CDS YP_002734339.1 225686367 7671064 541793..543913 1 NC_012442.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 543913 recG 7671064 recG Brucella melitensis ATCC 23457 ATP-dependent DNA helicase RecG YP_002734339.1 541793 D 546272 CDS YP_002734340.1 225686368 7671065 complement(544068..545891) 1 NC_012442.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 545891 glmS 7671065 glmS Brucella melitensis ATCC 23457 glucosamine--fructose-6-phosphate aminotransferase YP_002734340.1 544068 R 546272 CDS YP_002734341.1 225686369 7671066 complement(545995..547359) 1 NC_012442.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 547359 glmU 7671066 glmU Brucella melitensis ATCC 23457 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002734341.1 545995 R 546272 CDS YP_002734342.1 225686370 7671067 complement(547441..548202) 1 NC_012442.1 cytochrome c biogenesis protein 548202 7671067 BMEA_B0558 Brucella melitensis ATCC 23457 cytochrome c biogenesis protein YP_002734342.1 547441 R 546272 CDS YP_002734343.1 225686371 7671068 548351..550993 1 NC_012442.1 putative lysylphosphatidylglycerol synthetase 550993 7671068 BMEA_B0559 Brucella melitensis ATCC 23457 putative lysylphosphatidylglycerol synthetase YP_002734343.1 548351 D 546272 CDS YP_002734344.1 225686372 7671069 551242..552402 1 NC_012442.1 virulence factor family protein 552402 7671069 BMEA_B0560 Brucella melitensis ATCC 23457 virulence factor family protein YP_002734344.1 551242 D 546272 CDS YP_002734345.1 225686373 7671071 complement(552906..553406) 1 NC_012442.1 BA14K family protein 553406 7671071 BMEA_B0562 Brucella melitensis ATCC 23457 BA14K family protein YP_002734345.1 552906 R 546272 CDS YP_002734346.1 225686374 7671072 553724..555115 1 NC_012442.1 PAS domain S-box-containing protein 555115 7671072 BMEA_B0563 Brucella melitensis ATCC 23457 PAS domain S-box-containing protein YP_002734346.1 553724 D 546272 CDS YP_002734347.1 225686375 7671073 555243..556037 1 NC_012442.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 556037 lipB 7671073 lipB Brucella melitensis ATCC 23457 lipoate-protein ligase B YP_002734347.1 555243 D 546272 CDS YP_002734348.1 225686376 7671074 complement(556041..556970) 1 NC_012442.1 hypothetical protein 556970 7671074 BMEA_B0565 Brucella melitensis ATCC 23457 hypothetical protein YP_002734348.1 556041 R 546272 CDS YP_002734349.1 225686377 7671075 557275..559374 1 NC_012442.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 559374 parE 7671075 parE Brucella melitensis ATCC 23457 DNA topoisomerase IV subunit B YP_002734349.1 557275 D 546272 CDS YP_002734350.1 225686378 7671076 complement(559380..559553) 1 NC_012442.1 hypothetical protein 559553 7671076 BMEA_B0567 Brucella melitensis ATCC 23457 hypothetical protein YP_002734350.1 559380 R 546272 CDS YP_002734351.1 225686379 7671077 complement(559547..559771) 1 NC_012442.1 hypothetical protein 559771 7671077 BMEA_B0568 Brucella melitensis ATCC 23457 hypothetical protein YP_002734351.1 559547 R 546272 CDS YP_002734352.1 225686380 7671078 complement(559796..561277) 1 NC_012442.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 561277 gatA 7671078 gatA Brucella melitensis ATCC 23457 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002734352.1 559796 R 546272 CDS YP_002734353.1 225686381 7671079 complement(561336..561623) 1 NC_012442.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 561623 gatC 7671079 gatC Brucella melitensis ATCC 23457 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002734353.1 561336 R 546272 CDS YP_002734354.1 225686382 7671080 complement(561718..562431) 1 NC_012442.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 562431 7671080 BMEA_B0571 Brucella melitensis ATCC 23457 metal-dependent hydrolase YP_002734354.1 561718 R 546272 CDS YP_002734355.1 225686383 7671081 562531..563019 1 NC_012442.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 563019 7671081 BMEA_B0572 Brucella melitensis ATCC 23457 Holliday junction resolvase-like protein YP_002734355.1 562531 D 546272 CDS YP_002734356.1 225686384 7671082 complement(563004..564659) 1 NC_012442.1 acyl-CoA dehydrogenase domain-containing protein 564659 7671082 BMEA_B0573 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase domain-containing protein YP_002734356.1 563004 R 546272 CDS YP_002734357.1 225686385 7671083 564816..565784 1 NC_012442.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 565784 pyrB 7671083 pyrB Brucella melitensis ATCC 23457 aspartate carbamoyltransferase catalytic subunit YP_002734357.1 564816 D 546272 CDS YP_002734358.1 225686386 7671084 565781..567067 1 NC_012442.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 567067 pyrC 7671084 pyrC Brucella melitensis ATCC 23457 dihydroorotase YP_002734358.1 565781 D 546272 CDS YP_002734359.1 225686387 7671085 567142..567747 1 NC_012442.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 567747 7671085 BMEA_B0576 Brucella melitensis ATCC 23457 putative glycerol-3-phosphate acyltransferase PlsY YP_002734359.1 567142 D 546272 CDS YP_002734360.1 225686388 7671086 567744..568925 1 NC_012442.1 DNA protecting protein DprA 568925 dprA 7671086 dprA Brucella melitensis ATCC 23457 DNA protecting protein DprA YP_002734360.1 567744 D 546272 CDS YP_002734361.1 225686389 7671087 complement(568935..569102) 1 NC_012442.1 hypothetical protein 569102 7671087 BMEA_B0578 Brucella melitensis ATCC 23457 hypothetical protein YP_002734361.1 568935 R 546272 CDS YP_002734362.1 225686390 7671088 569358..571991 1 NC_012442.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 571991 topA 7671088 topA Brucella melitensis ATCC 23457 DNA topoisomerase I YP_002734362.1 569358 D 546272 CDS YP_002734363.1 225686391 7671089 571995..574346 1 NC_012442.1 ribonuclease R 574346 rnr 7671089 rnr Brucella melitensis ATCC 23457 ribonuclease R YP_002734363.1 571995 D 546272 CDS YP_002734364.1 225686392 7671090 574346..574807 1 NC_012442.1 hypothetical protein 574807 7671090 BMEA_B0581 Brucella melitensis ATCC 23457 hypothetical protein YP_002734364.1 574346 D 546272 CDS YP_002734365.1 225686393 7671091 574816..575547 1 NC_012442.1 NUDIX hydrolase 575547 7671091 BMEA_B0582 Brucella melitensis ATCC 23457 NUDIX hydrolase YP_002734365.1 574816 D 546272 CDS YP_002734366.1 225686394 7671092 575622..576764 1 NC_012442.1 major facilitator superfamily protein 576764 7671092 BMEA_B0583 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002734366.1 575622 D 546272 CDS YP_002734367.1 225686395 7671093 576923..577090 1 NC_012442.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 577090 rpmG 7671093 rpmG Brucella melitensis ATCC 23457 50S ribosomal protein L33 YP_002734367.1 576923 D 546272 CDS YP_002734368.1 225686396 7671094 complement(577197..578582) 1 NC_012442.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 578582 pleD 7671094 pleD Brucella melitensis ATCC 23457 response regulator PleD YP_002734368.1 577197 R 546272 CDS YP_002734369.1 225686397 7671095 complement(578579..578710) 1 NC_012442.1 hypothetical protein 578710 7671095 BMEA_B0586 Brucella melitensis ATCC 23457 hypothetical protein YP_002734369.1 578579 R 546272 CDS YP_002734370.1 225686398 7671096 complement(578703..579074) 1 NC_012442.1 hypothetical protein 579074 7671096 BMEA_B0587 Brucella melitensis ATCC 23457 hypothetical protein YP_002734370.1 578703 R 546272 CDS YP_002734371.1 225686399 7671097 579177..579542 1 NC_012442.1 hypothetical protein 579542 7671097 BMEA_B0588 Brucella melitensis ATCC 23457 hypothetical protein YP_002734371.1 579177 D 546272 CDS YP_002734372.1 225686400 7671099 580557..581894 1 NC_012442.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 581894 7671099 BMEA_B0590 Brucella melitensis ATCC 23457 DNA polymerase IV YP_002734372.1 580557 D 546272 CDS YP_002734373.1 225686401 7671100 582064..584253 1 NC_012442.1 hypothetical protein 584253 7671100 BMEA_B0591 Brucella melitensis ATCC 23457 hypothetical protein YP_002734373.1 582064 D 546272 CDS YP_002734374.1 225686402 7671101 complement(584233..584355) 1 NC_012442.1 hypothetical protein 584355 7671101 BMEA_B0592 Brucella melitensis ATCC 23457 hypothetical protein YP_002734374.1 584233 R 546272 CDS YP_002734375.1 225686403 7671103 complement(584782..585495) 1 NC_012442.1 GGDEF domain-containing protein 585495 7671103 BMEA_B0594 Brucella melitensis ATCC 23457 GGDEF domain-containing protein YP_002734375.1 584782 R 546272 CDS YP_002734376.1 225686404 7671104 complement(586403..586780) 1 NC_012442.1 Pyrimidine dimer DNA glycosylase 586780 7671104 BMEA_B0595 Brucella melitensis ATCC 23457 Pyrimidine dimer DNA glycosylase YP_002734376.1 586403 R 546272 CDS YP_002734377.1 225686405 7671105 586921..587226 1 NC_012442.1 hypothetical protein 587226 7671105 BMEA_B0596 Brucella melitensis ATCC 23457 hypothetical protein YP_002734377.1 586921 D 546272 CDS YP_002734378.1 225686406 7671106 587371..587559 1 NC_012442.1 hypothetical protein 587559 7671106 BMEA_B0597 Brucella melitensis ATCC 23457 hypothetical protein YP_002734378.1 587371 D 546272 CDS YP_002734379.1 225686407 7671107 587610..587903 1 NC_012442.1 hypothetical protein 587903 7671107 BMEA_B0598 Brucella melitensis ATCC 23457 hypothetical protein YP_002734379.1 587610 D 546272 CDS YP_002734380.1 225686408 7671108 587997..588671 1 NC_012442.1 exonuclease, DNA polymerase III, epsilon subunit family protein 588671 7671108 BMEA_B0599 Brucella melitensis ATCC 23457 exonuclease, DNA polymerase III, epsilon subunit family protein YP_002734380.1 587997 D 546272 CDS YP_002734381.1 225686409 7671110 589047..589328 1 NC_012442.1 hypothetical protein 589328 7671110 BMEA_B0601 Brucella melitensis ATCC 23457 hypothetical protein YP_002734381.1 589047 D 546272 CDS YP_002734382.1 225686410 7671111 complement(589429..590388) 1 NC_012442.1 putative transcriptional regulator lumQ 590388 7671111 BMEA_B0602 Brucella melitensis ATCC 23457 putative transcriptional regulator lumQ YP_002734382.1 589429 R 546272 CDS YP_002734383.1 225686411 7671112 complement(590556..590717) 1 NC_012442.1 hypothetical protein 590717 7671112 BMEA_B0603 Brucella melitensis ATCC 23457 hypothetical protein YP_002734383.1 590556 R 546272 CDS YP_002734384.1 225686412 7671113 complement(590743..591993) 1 NC_012442.1 FAD dependent oxidoreductase 591993 7671113 BMEA_B0604 Brucella melitensis ATCC 23457 FAD dependent oxidoreductase YP_002734384.1 590743 R 546272 CDS YP_002734385.1 225686413 7671115 complement(593033..594136) 1 NC_012442.1 hypothetical protein 594136 7671115 BMEA_B0606 Brucella melitensis ATCC 23457 hypothetical protein YP_002734385.1 593033 R 546272 CDS YP_002734386.1 225686414 7671116 594239..594688 1 NC_012442.1 hypothetical protein 594688 7671116 BMEA_B0607 Brucella melitensis ATCC 23457 hypothetical protein YP_002734386.1 594239 D 546272 CDS YP_002734387.1 225686415 7671117 594866..596695 1 NC_012442.1 amidohydrolase 3 596695 7671117 BMEA_B0608 Brucella melitensis ATCC 23457 amidohydrolase 3 YP_002734387.1 594866 D 546272 CDS YP_002734388.1 225686416 7671118 complement(596806..598008) 1 NC_012442.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 598008 pcaF 7671118 pcaF Brucella melitensis ATCC 23457 beta-ketoadipyl CoA thiolase YP_002734388.1 596806 R 546272 CDS YP_002734389.1 225686417 7671119 complement(598017..598706) 1 NC_012442.1 3-oxoacid CoA-transferase, B subunit 598706 7671119 BMEA_B0610 Brucella melitensis ATCC 23457 3-oxoacid CoA-transferase, B subunit YP_002734389.1 598017 R 546272 CDS YP_002734390.1 225686418 7671120 complement(598703..599410) 1 NC_012442.1 3-oxoacid CoA-transferase, A subunit 599410 7671120 BMEA_B0611 Brucella melitensis ATCC 23457 3-oxoacid CoA-transferase, A subunit YP_002734390.1 598703 R 546272 CDS YP_002734391.1 225686419 7671121 599594..600364 1 NC_012442.1 beta-ketoadipate pathway transcriptional regulator 600364 7671121 BMEA_B0612 Brucella melitensis ATCC 23457 beta-ketoadipate pathway transcriptional regulator YP_002734391.1 599594 D 546272 CDS YP_002734392.1 225686420 7671122 complement(600371..601288) 1 NC_012442.1 helix-turn-helix- domain containing protein 601288 7671122 BMEA_B0613 Brucella melitensis ATCC 23457 helix-turn-helix- domain containing protein YP_002734392.1 600371 R 546272 CDS YP_002734393.1 225686421 7671123 601401..602570 1 NC_012442.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 602570 pobA 7671123 pobA Brucella melitensis ATCC 23457 4-hydroxybenzoate 3-monooxygenase YP_002734393.1 601401 D 546272 CDS YP_002734394.1 225686422 7671124 complement(602980..603888) 1 NC_012442.1 pca operon transcription factor PcaQ 603888 pcaQ 7671124 pcaQ Brucella melitensis ATCC 23457 pca operon transcription factor PcaQ YP_002734394.1 602980 R 546272 CDS YP_002734395.1 225686423 7671125 603982..604785 1 NC_012442.1 3-oxoadipate enol-lactonase 604785 pcaD 7671125 pcaD Brucella melitensis ATCC 23457 3-oxoadipate enol-lactonase YP_002734395.1 603982 D 546272 CDS YP_002734396.1 225686424 7671126 604789..605205 1 NC_012442.1 4-carboxymuconolactone decarboxylase 605205 pcaC 7671126 pcaC Brucella melitensis ATCC 23457 4-carboxymuconolactone decarboxylase YP_002734396.1 604789 D 546272 CDS YP_002734397.1 225686425 7671128 605944..606561 1 NC_012442.1 protocatechuate 3,4-dioxygenase subunit alpha 606561 pcaG 7671128 pcaG Brucella melitensis ATCC 23457 protocatechuate 3,4-dioxygenase subunit alpha YP_002734397.1 605944 D 546272 CDS YP_002734398.1 225686426 7671129 606565..607629 1 NC_012442.1 Catalyzes the cycloisomerization of cis,cis-muconate; 3-carboxy-cis,cis-muconate cycloisomerase 607629 pcaB 7671129 pcaB Brucella melitensis ATCC 23457 3-carboxy-cis,cis-muconate cycloisomerase YP_002734398.1 606565 D 546272 CDS YP_002734399.1 225686427 7671130 607765..608937 1 NC_012442.1 amino acid ABC transporter substrate-binding portion 608937 7671130 BMEA_B0621 Brucella melitensis ATCC 23457 amino acid ABC transporter substrate-binding portion YP_002734399.1 607765 D 546272 CDS YP_002734400.1 225686428 7671131 609109..609978 1 NC_012442.1 hypothetical protein 609978 7671131 BMEA_B0622 Brucella melitensis ATCC 23457 hypothetical protein YP_002734400.1 609109 D 546272 CDS YP_002734401.1 225686429 7671133 610957..611706 1 NC_012442.1 ABC transporter 611706 7671133 BMEA_B0624 Brucella melitensis ATCC 23457 ABC transporter YP_002734401.1 610957 D 546272 CDS YP_002734402.1 225686430 7671134 611703..612419 1 NC_012442.1 ABC transporter 612419 7671134 BMEA_B0625 Brucella melitensis ATCC 23457 ABC transporter YP_002734402.1 611703 D 546272 CDS YP_002734403.1 225686431 7671135 complement(612420..614261) 1 NC_012442.1 adenine deaminase 614261 ade 7671135 ade Brucella melitensis ATCC 23457 adenine deaminase YP_002734403.1 612420 R 546272 CDS YP_002734404.1 225686432 7671136 614324..615364 1 NC_012442.1 dipeptidase 615364 7671136 BMEA_B0627 Brucella melitensis ATCC 23457 dipeptidase YP_002734404.1 614324 D 546272 CDS YP_002734405.1 225686433 7671137 615697..616998 1 NC_012442.1 sn-glycerol-3-phosphate-binding periplasmic protein UgpB 616998 7671137 BMEA_B0628 Brucella melitensis ATCC 23457 sn-glycerol-3-phosphate-binding periplasmic protein UgpB YP_002734405.1 615697 D 546272 CDS YP_002734406.1 225686434 7671138 617071..617943 1 NC_012442.1 sn-glycerol-3-phosphate transport system permease UgpA 617943 7671138 BMEA_B0629 Brucella melitensis ATCC 23457 sn-glycerol-3-phosphate transport system permease UgpA YP_002734406.1 617071 D 546272 CDS YP_002734407.1 225686435 7671139 617955..618803 1 NC_012442.1 sn-glycerol-3-phosphate transport system permease UgpE 618803 7671139 BMEA_B0630 Brucella melitensis ATCC 23457 sn-glycerol-3-phosphate transport system permease UgpE YP_002734407.1 617955 D 546272 CDS YP_002734408.1 225686436 7671140 618803..619858 1 NC_012442.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 619858 ugpC 7671140 ugpC Brucella melitensis ATCC 23457 glycerol-3-phosphate transporter ATP-binding subunit YP_002734408.1 618803 D 546272 CDS YP_002734409.1 225686437 7671142 complement(621970..622569) 1 NC_012442.1 CMP/dCMP deaminase zinc-binding 622569 7671142 BMEA_B0633 Brucella melitensis ATCC 23457 CMP/dCMP deaminase zinc-binding YP_002734409.1 621970 R 546272 CDS YP_002734410.1 225686438 7671143 complement(622630..623922) 1 NC_012442.1 Xanthine/uracil/vitamin C permease 623922 7671143 BMEA_B0634 Brucella melitensis ATCC 23457 Xanthine/uracil/vitamin C permease YP_002734410.1 622630 R 546272 CDS YP_002734411.1 225686439 7671144 complement(624191..624355) 1 NC_012442.1 hypothetical protein 624355 7671144 BMEA_B0635 Brucella melitensis ATCC 23457 hypothetical protein YP_002734411.1 624191 R 546272 CDS YP_002734412.1 225686440 7671145 complement(624360..624848) 1 NC_012442.1 hypothetical protein 624848 7671145 BMEA_B0636 Brucella melitensis ATCC 23457 hypothetical protein YP_002734412.1 624360 R 546272 CDS YP_002734413.1 225686441 7671146 625031..625195 1 NC_012442.1 hypothetical protein 625195 7671146 BMEA_B0637 Brucella melitensis ATCC 23457 hypothetical protein YP_002734413.1 625031 D 546272 CDS YP_002734414.1 225686442 7671147 complement(625199..625336) 1 NC_012442.1 hypothetical protein 625336 7671147 BMEA_B0638 Brucella melitensis ATCC 23457 hypothetical protein YP_002734414.1 625199 R 546272 CDS YP_002734415.1 225686443 7671148 625595..626512 1 NC_012442.1 hypothetical protein 626512 7671148 BMEA_B0639 Brucella melitensis ATCC 23457 hypothetical protein YP_002734415.1 625595 D 546272 CDS YP_002734416.1 225686444 7671149 626594..627484 1 NC_012442.1 aminotransferase 627484 7671149 BMEA_B0640 Brucella melitensis ATCC 23457 aminotransferase YP_002734416.1 626594 D 546272 CDS YP_002734417.1 225686445 7671150 627469..627660 1 NC_012442.1 hypothetical protein 627660 7671150 BMEA_B0641 Brucella melitensis ATCC 23457 hypothetical protein YP_002734417.1 627469 D 546272 CDS YP_002734418.1 225686446 7671151 627657..628418 1 NC_012442.1 hypothetical protein 628418 7671151 BMEA_B0642 Brucella melitensis ATCC 23457 hypothetical protein YP_002734418.1 627657 D 546272 CDS YP_002734419.1 225686447 7671153 complement(630239..630724) 1 NC_012442.1 hypothetical protein 630724 7671153 BMEA_B0644 Brucella melitensis ATCC 23457 hypothetical protein YP_002734419.1 630239 R 546272 CDS YP_002734420.1 225686448 7671154 630275..630679 1 NC_012442.1 hypothetical protein 630679 7671154 BMEA_B0645 Brucella melitensis ATCC 23457 hypothetical protein YP_002734420.1 630275 D 546272 CDS YP_002734421.1 225686449 7671155 630892..632250 1 NC_012442.1 aldehyde dehydrogenase family protein 632250 7671155 BMEA_B0646 Brucella melitensis ATCC 23457 aldehyde dehydrogenase family protein YP_002734421.1 630892 D 546272 CDS YP_002734422.1 225686450 7671156 632728..633675 1 NC_012442.1 periplasmic binding protein 633675 7671156 BMEA_B0647 Brucella melitensis ATCC 23457 periplasmic binding protein YP_002734422.1 632728 D 546272 CDS YP_002734423.1 225686451 7671157 633732..634694 1 NC_012442.1 transport system permease 634694 7671157 BMEA_B0648 Brucella melitensis ATCC 23457 transport system permease YP_002734423.1 633732 D 546272 CDS YP_002734424.1 225686452 7671158 634687..635640 1 NC_012442.1 transport system permease 635640 7671158 BMEA_B0649 Brucella melitensis ATCC 23457 transport system permease YP_002734424.1 634687 D 546272 CDS YP_002734425.1 225686453 7671159 635637..636395 1 NC_012442.1 ABC transporter 636395 7671159 BMEA_B0650 Brucella melitensis ATCC 23457 ABC transporter YP_002734425.1 635637 D 546272 CDS YP_002734426.1 225686454 7671160 complement(636448..637047) 1 NC_012442.1 transcriptional regulator 637047 7671160 BMEA_B0651 Brucella melitensis ATCC 23457 transcriptional regulator YP_002734426.1 636448 R 546272 CDS YP_002734427.1 225686455 7671161 637185..640796 1 NC_012442.1 5-oxoprolinase 640796 7671161 BMEA_B0652 Brucella melitensis ATCC 23457 5-oxoprolinase YP_002734427.1 637185 D 546272 CDS YP_002734428.1 225686456 7671162 641082..641855 1 NC_012442.1 family 3 extracellular solute-binding protein 641855 7671162 BMEA_B0653 Brucella melitensis ATCC 23457 family 3 extracellular solute-binding protein YP_002734428.1 641082 D 546272 CDS YP_002734429.1 225686457 7671163 642035..642715 1 NC_012442.1 amino acid ABC transporter permease 642715 7671163 BMEA_B0654 Brucella melitensis ATCC 23457 amino acid ABC transporter permease YP_002734429.1 642035 D 546272 CDS YP_002734430.1 225686458 7671164 642712..643473 1 NC_012442.1 ABC transporter 643473 7671164 BMEA_B0655 Brucella melitensis ATCC 23457 ABC transporter YP_002734430.1 642712 D 546272 CDS YP_002734431.1 225686459 7671165 643625..645211 1 NC_012442.1 Ppx/GppA phosphatase 645211 7671165 BMEA_B0656 Brucella melitensis ATCC 23457 Ppx/GppA phosphatase YP_002734431.1 643625 D 546272 CDS YP_002734432.1 225686460 7671166 645213..645935 1 NC_012442.1 Ribosomal RNA large subunit methyltransferase J 645935 7671166 BMEA_B0657 Brucella melitensis ATCC 23457 Ribosomal RNA large subunit methyltransferase J YP_002734432.1 645213 D 546272 CDS YP_002734433.1 225686461 7671167 complement(646134..647543) 1 NC_012442.1 drug resistance transporter, EmrB/QacA subfamily protein 647543 7671167 BMEA_B0658 Brucella melitensis ATCC 23457 drug resistance transporter, EmrB/QacA subfamily protein YP_002734433.1 646134 R 546272 CDS YP_002734434.1 225686462 7671168 complement(647587..647871) 1 NC_012442.1 hypothetical protein 647871 7671168 BMEA_B0659 Brucella melitensis ATCC 23457 hypothetical protein YP_002734434.1 647587 R 546272 CDS YP_002734435.1 225686463 7671169 complement(648105..649220) 1 NC_012442.1 ABC transporter 649220 7671169 BMEA_B0660 Brucella melitensis ATCC 23457 ABC transporter YP_002734435.1 648105 R 546272 CDS YP_002734436.1 225686464 7671170 complement(649239..650120) 1 NC_012442.1 hypothetical protein 650120 7671170 BMEA_B0661 Brucella melitensis ATCC 23457 hypothetical protein YP_002734436.1 649239 R 546272 CDS YP_002734437.1 225686465 7671171 complement(650117..651166) 1 NC_012442.1 putative starch degradation products transport system permease amyD 651166 7671171 BMEA_B0662 Brucella melitensis ATCC 23457 putative starch degradation products transport system permease amyD YP_002734437.1 650117 R 546272 CDS YP_002734438.1 225686466 7671172 complement(651274..652539) 1 NC_012442.1 putative sugar-binding periplasmic protein 652539 7671172 BMEA_B0663 Brucella melitensis ATCC 23457 putative sugar-binding periplasmic protein YP_002734438.1 651274 R 546272 CDS YP_002734439.1 225686467 7671173 complement(653034..653282) 1 NC_012442.1 hypothetical protein 653282 7671173 BMEA_B0664 Brucella melitensis ATCC 23457 hypothetical protein YP_002734439.1 653034 R 546272 CDS YP_002734440.1 225686468 7671174 653426..653902 1 NC_012442.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; riboflavin synthase subunit beta 653902 7671174 BMEA_B0667 Brucella melitensis ATCC 23457 riboflavin synthase subunit beta YP_002734440.1 653426 D 546272 CDS YP_002734441.1 225686469 7671175 complement(653903..654712) 1 NC_012442.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 654712 fdhD 7671175 fdhD Brucella melitensis ATCC 23457 formate dehydrogenase accessory protein YP_002734441.1 653903 R 546272 CDS YP_002734442.1 225686470 7671176 654822..655166 1 NC_012442.1 hypothetical protein 655166 7671176 BMEA_B0669 Brucella melitensis ATCC 23457 hypothetical protein YP_002734442.1 654822 D 546272 CDS YP_002734443.1 225686471 7671177 complement(655236..655637) 1 NC_012442.1 hypothetical protein 655637 7671177 BMEA_B0671 Brucella melitensis ATCC 23457 hypothetical protein YP_002734443.1 655236 R 546272 CDS YP_002734444.1 225686472 7671178 complement(655815..657584) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 657584 7671178 BMEA_B0672 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734444.1 655815 R 546272 CDS YP_002734445.1 225686473 7671179 complement(657605..658621) 1 NC_012442.1 family 1 extracellular solute-binding protein 658621 7671179 BMEA_B0673 Brucella melitensis ATCC 23457 family 1 extracellular solute-binding protein YP_002734445.1 657605 R 546272 CDS YP_002734446.1 225686474 7671180 complement(658747..659850) 1 NC_012442.1 ABC transporter 659850 7671180 BMEA_B0674 Brucella melitensis ATCC 23457 ABC transporter YP_002734446.1 658747 R 546272 CDS YP_002734447.1 225686475 7671181 659901..660071 1 NC_012442.1 hypothetical protein 660071 7671181 BMEA_B0675 Brucella melitensis ATCC 23457 hypothetical protein YP_002734447.1 659901 D 546272 CDS YP_002734448.1 225686476 7671183 complement(661671..662192) 1 NC_012442.1 Superoxide dismutase, copper/zinc binding 662192 7671183 BMEA_B0677 Brucella melitensis ATCC 23457 Superoxide dismutase, copper/zinc binding YP_002734448.1 661671 R 546272 CDS YP_002734449.1 225686477 7671184 complement(662465..664069) 1 NC_012442.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 664069 7671184 BMEA_B0678 Brucella melitensis ATCC 23457 multicopper oxidase YP_002734449.1 662465 R 546272 CDS YP_002734450.1 225686478 7671185 complement(664129..664524) 1 NC_012442.1 hypothetical protein 664524 7671185 BMEA_B0679 Brucella melitensis ATCC 23457 hypothetical protein YP_002734450.1 664129 R 546272 CDS YP_002734451.1 225686479 7671186 664777..666057 1 NC_012442.1 major facilitator superfamily protein 666057 7671186 BMEA_B0680 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002734451.1 664777 D 546272 CDS YP_002734452.1 225686480 7671187 complement(666032..666661) 1 NC_012442.1 alkylhydroperoxidase 666661 ahpD 7671187 ahpD Brucella melitensis ATCC 23457 alkylhydroperoxidase YP_002734452.1 666032 R 546272 CDS YP_002734453.1 225686481 7671188 complement(666741..667295) 1 NC_012442.1 Thioredoxin peroxidase 2 667295 7671188 BMEA_B0682 Brucella melitensis ATCC 23457 Thioredoxin peroxidase 2 YP_002734453.1 666741 R 546272 CDS YP_002734454.1 225686482 7671189 667421..668326 1 NC_012442.1 LysR family transcriptional regulator 668326 7671189 BMEA_B0684 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002734454.1 667421 D 546272 CDS YP_002734455.1 225686483 7671190 complement(668356..669423) 1 NC_012442.1 hypothetical protein 669423 7671190 BMEA_B0685 Brucella melitensis ATCC 23457 hypothetical protein YP_002734455.1 668356 R 546272 CDS YP_002734456.1 225686484 7671191 complement(669521..670525) 1 NC_012442.1 Rhizopine catabolism protein mocA 670525 7671191 BMEA_B0686 Brucella melitensis ATCC 23457 Rhizopine catabolism protein mocA YP_002734456.1 669521 R 546272 CDS YP_002734457.1 225686485 7671192 670699..671529 1 NC_012442.1 RpiR family transcriptional regulator 671529 7671192 BMEA_B0687 Brucella melitensis ATCC 23457 RpiR family transcriptional regulator YP_002734457.1 670699 D 546272 CDS YP_002734458.1 225686486 7671193 671621..673525 1 NC_012442.1 Fructokinase-1 673525 7671193 BMEA_B0688 Brucella melitensis ATCC 23457 Fructokinase-1 YP_002734458.1 671621 D 546272 CDS YP_002734459.1 225686487 7671194 673558..675381 1 NC_012442.1 thiamine pyrophosphate protein 675381 7671194 BMEA_B0689 Brucella melitensis ATCC 23457 thiamine pyrophosphate protein YP_002734459.1 673558 D 546272 CDS YP_002734460.1 225686488 7671195 675385..676287 1 NC_012442.1 Rhizopine catabolism protein mocC 676287 7671195 BMEA_B0690 Brucella melitensis ATCC 23457 Rhizopine catabolism protein mocC YP_002734460.1 675385 D 546272 CDS YP_002734461.1 225686489 7671196 676291..677100 1 NC_012442.1 Myo-inositol catabolism IolB domain-containing protein 677100 7671196 BMEA_B0691 Brucella melitensis ATCC 23457 Myo-inositol catabolism IolB domain-containing protein YP_002734461.1 676291 D 546272 CDS YP_002734462.1 225686490 7671197 complement(677132..677932) 1 NC_012442.1 inositol monophosphatase family protein 677932 7671197 BMEA_B0692 Brucella melitensis ATCC 23457 inositol monophosphatase family protein YP_002734462.1 677132 R 546272 CDS YP_002734463.1 225686491 7671198 complement(677953..679014) 1 NC_012442.1 ABC transporter 679014 7671198 BMEA_B0693 Brucella melitensis ATCC 23457 ABC transporter YP_002734463.1 677953 R 546272 CDS YP_002734464.1 225686492 7671199 complement(679011..681236) 1 NC_012442.1 ferric transport system permease FbpB 681236 7671199 BMEA_B0694 Brucella melitensis ATCC 23457 ferric transport system permease FbpB YP_002734464.1 679011 R 546272 CDS YP_002734465.1 225686493 7671200 complement(681371..682396) 1 NC_012442.1 iron ABC transporter substrate-binding protein 682396 7671200 BMEA_B0695 Brucella melitensis ATCC 23457 iron ABC transporter substrate-binding protein YP_002734465.1 681371 R 546272 CDS YP_002734466.1 225686494 7671201 complement(682626..686309) 1 NC_012442.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 686309 7671201 BMEA_B0697 Brucella melitensis ATCC 23457 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002734466.1 682626 R 546272 CDS YP_002734467.1 225686495 7671202 686472..686966 1 NC_012442.1 proline dehydrogenase transcriptional activator 686966 7671202 BMEA_B0698 Brucella melitensis ATCC 23457 proline dehydrogenase transcriptional activator YP_002734467.1 686472 D 546272 CDS YP_002734468.1 225686496 7671204 complement(687996..690794) 1 NC_012442.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 690794 gcvP 7671204 gcvP Brucella melitensis ATCC 23457 glycine dehydrogenase YP_002734468.1 687996 R 546272 CDS YP_002734469.1 225686497 7671205 complement(690799..691167) 1 NC_012442.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 691167 gcvH 7671205 gcvH Brucella melitensis ATCC 23457 glycine cleavage system protein H YP_002734469.1 690799 R 546272 CDS YP_002734470.1 225686498 7671206 complement(691173..692276) 1 NC_012442.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 692276 gcvT 7671206 gcvT Brucella melitensis ATCC 23457 glycine cleavage system aminomethyltransferase T YP_002734470.1 691173 R 546272 CDS YP_002734471.1 225686499 7671207 692918..693076 1 NC_012442.1 hypothetical protein 693076 7671207 BMEA_B0706 Brucella melitensis ATCC 23457 hypothetical protein YP_002734471.1 692918 D 546272 CDS YP_002734472.1 225686500 7671209 complement(694594..695436) 1 NC_012442.1 RpiR family transcriptional regulator 695436 7671209 BMEA_B0708 Brucella melitensis ATCC 23457 RpiR family transcriptional regulator YP_002734472.1 694594 R 546272 CDS YP_002734473.1 225686501 7671210 695565..696362 1 NC_012442.1 N-formylglutamate amidohydrolase 696362 7671210 BMEA_B0709 Brucella melitensis ATCC 23457 N-formylglutamate amidohydrolase YP_002734473.1 695565 D 546272 CDS YP_002734474.1 225686502 7671211 696426..697793 1 NC_012442.1 glutamate--ammonia ligase 697793 7671211 BMEA_B0710 Brucella melitensis ATCC 23457 glutamate--ammonia ligase YP_002734474.1 696426 D 546272 CDS YP_002734475.1 225686503 7671212 complement(697787..697903) 1 NC_012442.1 hypothetical protein 697903 7671212 BMEA_B0711 Brucella melitensis ATCC 23457 hypothetical protein YP_002734475.1 697787 R 546272 CDS YP_002734476.1 225686504 7671213 697894..699063 1 NC_012442.1 1,3-propanediol dehydrogenase 699063 7671213 BMEA_B0712 Brucella melitensis ATCC 23457 1,3-propanediol dehydrogenase YP_002734476.1 697894 D 546272 CDS YP_002734477.1 225686505 7671214 699245..699688 1 NC_012442.1 BA14K family protein 699688 7671214 BMEA_B0713 Brucella melitensis ATCC 23457 BA14K family protein YP_002734477.1 699245 D 546272 CDS YP_002734478.1 225686506 7671215 699818..700015 1 NC_012442.1 hypothetical protein 700015 7671215 BMEA_B0714 Brucella melitensis ATCC 23457 hypothetical protein YP_002734478.1 699818 D 546272 CDS YP_002734479.1 225686507 7671216 700097..700996 1 NC_012442.1 hypothetical protein 700996 7671216 BMEA_B0715 Brucella melitensis ATCC 23457 hypothetical protein YP_002734479.1 700097 D 546272 CDS YP_002734480.1 225686508 7671217 complement(701042..701908) 1 NC_012442.1 glycine/betaine ABC transporter substrate-binding protein 701908 7671217 BMEA_B0716 Brucella melitensis ATCC 23457 glycine/betaine ABC transporter substrate-binding protein YP_002734480.1 701042 R 546272 CDS YP_002734481.1 225686509 7671218 complement(701962..702867) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 702867 7671218 BMEA_B0717 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734481.1 701962 R 546272 CDS YP_002734482.1 225686510 7671219 complement(702930..704096) 1 NC_012442.1 glycine betaine/L-proline transporter ATP binding subunit 704096 proV 7671219 proV Brucella melitensis ATCC 23457 glycine betaine/L-proline transporter ATP binding subunit YP_002734482.1 702930 R 546272 CDS YP_002734483.1 225686511 7671220 complement(704309..704494) 1 NC_012442.1 hypothetical protein 704494 7671220 BMEA_B0719 Brucella melitensis ATCC 23457 hypothetical protein YP_002734483.1 704309 R 546272 CDS YP_002734484.1 225686512 7671221 complement(704657..705130) 1 NC_012442.1 hypothetical protein 705130 7671221 BMEA_B0720 Brucella melitensis ATCC 23457 hypothetical protein YP_002734484.1 704657 R 546272 CDS YP_002734485.1 225686513 7671222 complement(705144..706211) 1 NC_012442.1 alanine racemase domain-containing protein 706211 7671222 BMEA_B0721 Brucella melitensis ATCC 23457 alanine racemase domain-containing protein YP_002734485.1 705144 R 546272 CDS YP_002734486.1 225686514 7671223 complement(706216..707097) 1 NC_012442.1 RpiR family transcriptional regulator 707097 7671223 BMEA_B0722 Brucella melitensis ATCC 23457 RpiR family transcriptional regulator YP_002734486.1 706216 R 546272 CDS YP_002734487.1 225686515 7671224 complement(707105..708157) 1 NC_012442.1 ATP-binding transport protein SmoK 708157 7671224 BMEA_B0723 Brucella melitensis ATCC 23457 ATP-binding transport protein SmoK YP_002734487.1 707105 R 546272 CDS YP_002734488.1 225686516 7671225 complement(708162..708935) 1 NC_012442.1 Peroxisomal 2,4-dienoyl-CoA reductase 708935 7671225 BMEA_B0724 Brucella melitensis ATCC 23457 Peroxisomal 2,4-dienoyl-CoA reductase YP_002734488.1 708162 R 546272 CDS YP_002734489.1 225686517 7671226 709115..710350 1 NC_012442.1 family 1 extracellular solute-binding protein 710350 7671226 BMEA_B0725 Brucella melitensis ATCC 23457 family 1 extracellular solute-binding protein YP_002734489.1 709115 D 546272 CDS YP_002734490.1 225686518 7671227 710422..711291 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 711291 7671227 BMEA_B0726 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734490.1 710422 D 546272 CDS YP_002734491.1 225686519 7671228 711288..712115 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 712115 7671228 BMEA_B0727 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734491.1 711288 D 546272 CDS YP_002734492.1 225686520 7671229 712128..712499 1 NC_012442.1 endoribonuclease L-PSP 712499 7671229 BMEA_B0728 Brucella melitensis ATCC 23457 endoribonuclease L-PSP YP_002734492.1 712128 D 546272 CDS YP_002734493.1 225686521 7671230 712526..713995 1 NC_012442.1 hypothetical protein 713995 7671230 BMEA_B0729 Brucella melitensis ATCC 23457 hypothetical protein YP_002734493.1 712526 D 546272 CDS YP_002734494.1 225686522 7671231 complement(714154..714396) 1 NC_012442.1 hypothetical protein 714396 7671231 BMEA_B0730 Brucella melitensis ATCC 23457 hypothetical protein YP_002734494.1 714154 R 546272 CDS YP_002734495.1 225686523 7671232 complement(714454..715248) 1 NC_012442.1 ABC transporter 715248 7671232 BMEA_B0731 Brucella melitensis ATCC 23457 ABC transporter YP_002734495.1 714454 R 546272 CDS YP_002734496.1 225686524 7671233 complement(715245..716288) 1 NC_012442.1 transport system permease 716288 7671233 BMEA_B0732 Brucella melitensis ATCC 23457 transport system permease YP_002734496.1 715245 R 546272 CDS YP_002734497.1 225686525 7671234 complement(716285..717319) 1 NC_012442.1 periplasmic binding protein 717319 7671234 BMEA_B0733 Brucella melitensis ATCC 23457 periplasmic binding protein YP_002734497.1 716285 R 546272 CDS YP_002734498.1 225686526 7671235 complement(717870..718736) 1 NC_012442.1 p-hydroxybenzoic acid efflux pump subunit aaeA 718736 7671235 BMEA_B0736 Brucella melitensis ATCC 23457 p-hydroxybenzoic acid efflux pump subunit aaeA YP_002734498.1 717870 R 546272 CDS YP_002734499.1 225686527 7671236 complement(718733..718942) 1 NC_012442.1 hypothetical protein 718942 7671236 BMEA_B0737 Brucella melitensis ATCC 23457 hypothetical protein YP_002734499.1 718733 R 546272 CDS YP_002734500.1 225686528 7671237 complement(718969..721065) 1 NC_012442.1 Fusaric acid resistance protein conserved protein 721065 7671237 BMEA_B0738 Brucella melitensis ATCC 23457 Fusaric acid resistance protein conserved protein YP_002734500.1 718969 R 546272 CDS YP_002734501.1 225686529 7671238 complement(721108..721545) 1 NC_012442.1 MarR family transcriptional regulator 721545 7671238 BMEA_B0739 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002734501.1 721108 R 546272 CDS YP_002734502.1 225686530 7671239 721813..722541 1 NC_012442.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 722541 7671239 BMEA_B0740 Brucella melitensis ATCC 23457 16S ribosomal RNA methyltransferase RsmE YP_002734502.1 721813 D 546272 CDS YP_002734503.1 225686531 7671240 722641..724014 1 NC_012442.1 glutamate--cysteine ligase 724014 7671240 BMEA_B0741 Brucella melitensis ATCC 23457 glutamate--cysteine ligase YP_002734503.1 722641 D 546272 CDS YP_002734504.1 225686532 7671241 complement(724080..725615) 1 NC_012442.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 725615 xseA 7671241 xseA Brucella melitensis ATCC 23457 exodeoxyribonuclease VII large subunit YP_002734504.1 724080 R 546272 CDS YP_002734505.1 225686533 7671243 726818..727120 1 NC_012442.1 hypothetical protein 727120 7671243 BMEA_B0744 Brucella melitensis ATCC 23457 hypothetical protein YP_002734505.1 726818 D 546272 CDS YP_002734506.1 225686534 7671244 727114..727368 1 NC_012442.1 hypothetical protein 727368 7671244 BMEA_B0745 Brucella melitensis ATCC 23457 hypothetical protein YP_002734506.1 727114 D 546272 CDS YP_002734507.1 225686535 7671245 727372..728802 1 NC_012442.1 glutamine synthetase 728802 7671245 BMEA_B0746 Brucella melitensis ATCC 23457 glutamine synthetase YP_002734507.1 727372 D 546272 CDS YP_002734508.1 225686536 7671246 728899..729216 1 NC_012442.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 729216 7671246 BMEA_B0747 Brucella melitensis ATCC 23457 hypothetical protein YP_002734508.1 728899 D 546272 CDS YP_002734509.1 225686537 7671247 729270..730556 1 NC_012442.1 FAD dependent oxidoreductase 730556 7671247 BMEA_B0748 Brucella melitensis ATCC 23457 FAD dependent oxidoreductase YP_002734509.1 729270 D 546272 CDS YP_002734510.1 225686538 7671248 complement(730567..730983) 1 NC_012442.1 MarR family transcriptional regulator 730983 7671248 BMEA_B0749 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002734510.1 730567 R 546272 CDS YP_002734511.1 225686539 7671249 complement(731293..732093) 1 NC_012442.1 hypothetical protein 732093 7671249 BMEA_B0750 Brucella melitensis ATCC 23457 hypothetical protein YP_002734511.1 731293 R 546272 CDS YP_002734512.1 225686540 7671250 complement(732352..732816) 1 NC_012442.1 Leucine-responsive regulatory protein 732816 7671250 BMEA_B0751 Brucella melitensis ATCC 23457 Leucine-responsive regulatory protein YP_002734512.1 732352 R 546272 CDS YP_002734513.1 225686541 7671251 733192..733932 1 NC_012442.1 AzlC family protein 733932 7671251 BMEA_B0752 Brucella melitensis ATCC 23457 AzlC family protein YP_002734513.1 733192 D 546272 CDS YP_002734514.1 225686542 7671252 733929..734228 1 NC_012442.1 branched-chain amino acid transport 734228 7671252 BMEA_B0753 Brucella melitensis ATCC 23457 branched-chain amino acid transport YP_002734514.1 733929 D 546272 CDS YP_002734515.1 225686543 7671253 734251..735726 1 NC_012442.1 major facilitator superfamily protein 735726 7671253 BMEA_B0754 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002734515.1 734251 D 546272 CDS YP_002734516.1 225686544 7671254 complement(735815..736564) 1 NC_012442.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 736564 fabG 7671254 fabG Brucella melitensis ATCC 23457 3-ketoacyl-ACP reductase YP_002734516.1 735815 R 546272 CDS YP_002734517.1 225686545 7671255 736835..738310 1 NC_012442.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 738310 zwf 7671255 zwf Brucella melitensis ATCC 23457 glucose-6-phosphate 1-dehydrogenase YP_002734517.1 736835 D 546272 CDS YP_002734518.1 225686546 7671256 738439..739137 1 NC_012442.1 6-phosphogluconolactonase 739137 pgl 7671256 pgl Brucella melitensis ATCC 23457 6-phosphogluconolactonase YP_002734518.1 738439 D 546272 CDS YP_002734519.1 225686547 7671257 739155..740996 1 NC_012442.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 740996 edd 7671257 edd Brucella melitensis ATCC 23457 phosphogluconate dehydratase YP_002734519.1 739155 D 546272 CDS YP_002734520.1 225686548 7671258 complement(741088..741987) 1 NC_012442.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 741987 7671258 BMEA_B0759 Brucella melitensis ATCC 23457 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002734520.1 741088 R 546272 CDS YP_002734521.1 225686549 7671259 742308..743123 1 NC_012442.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 743123 proC 7671259 proC Brucella melitensis ATCC 23457 pyrroline-5-carboxylate reductase YP_002734521.1 742308 D 546272 CDS YP_002734522.1 225686550 7671260 complement(743214..743966) 1 NC_012442.1 glutathione import ATP-binding protein GsiA 743966 7671260 BMEA_B0761 Brucella melitensis ATCC 23457 glutathione import ATP-binding protein GsiA YP_002734522.1 743214 R 546272 CDS YP_002734523.1 225686551 7671262 complement(744710..745540) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 745540 7671262 BMEA_B0763 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734523.1 744710 R 546272 CDS YP_002734524.1 225686552 7671263 complement(745537..746535) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 746535 7671263 BMEA_B0764 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734524.1 745537 R 546272 CDS YP_002734525.1 225686553 7671264 complement(746553..748166) 1 NC_012442.1 family 5 extracellular solute-binding protein 748166 7671264 BMEA_B0765 Brucella melitensis ATCC 23457 family 5 extracellular solute-binding protein YP_002734525.1 746553 R 546272 CDS YP_002734526.1 225686554 7671265 748521..748865 1 NC_012442.1 hypothetical protein 748865 7671265 BMEA_B0766 Brucella melitensis ATCC 23457 hypothetical protein YP_002734526.1 748521 D 546272 CDS YP_002734527.1 225686555 7671266 749014..749673 1 NC_012442.1 carbonate dehydratase 749673 7671266 BMEA_B0767 Brucella melitensis ATCC 23457 carbonate dehydratase YP_002734527.1 749014 D 546272 CDS YP_002734528.1 225686556 7671267 complement(749735..750145) 1 NC_012442.1 hypothetical protein 750145 7671267 BMEA_B0768 Brucella melitensis ATCC 23457 hypothetical protein YP_002734528.1 749735 R 546272 CDS YP_002734529.1 225686557 7671268 750340..751995 1 NC_012442.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 751995 lysK 7671268 lysK Brucella melitensis ATCC 23457 lysyl-tRNA synthetase YP_002734529.1 750340 D 546272 CDS YP_002734530.1 225686558 7671269 complement(752083..753042) 1 NC_012442.1 hypothetical protein 753042 7671269 BMEA_B0770 Brucella melitensis ATCC 23457 hypothetical protein YP_002734530.1 752083 R 546272 CDS YP_002734531.1 225686559 7671270 complement(753043..753699) 1 NC_012442.1 Repressor protein C 753699 7671270 BMEA_B0771 Brucella melitensis ATCC 23457 Repressor protein C YP_002734531.1 753043 R 546272 CDS YP_002734532.1 225686560 7671271 complement(753937..756153) 1 NC_012442.1 Fatty acid oxidation complex subunit alpha 756153 7671271 BMEA_B0772 Brucella melitensis ATCC 23457 Fatty acid oxidation complex subunit alpha YP_002734532.1 753937 R 546272 CDS YP_002734533.1 225686561 7671272 complement(756169..757377) 1 NC_012442.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 757377 7671272 BMEA_B0773 Brucella melitensis ATCC 23457 acetyl-CoA acetyltransferase YP_002734533.1 756169 R 546272 CDS YP_002734534.1 225686562 7671273 complement(757442..759235) 1 NC_012442.1 acyl-CoA dehydrogenase domain-containing protein 759235 7671273 BMEA_B0774 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase domain-containing protein YP_002734534.1 757442 R 546272 CDS YP_002734535.1 225686563 7671274 complement(759210..759413) 1 NC_012442.1 hypothetical protein 759413 7671274 BMEA_B0775 Brucella melitensis ATCC 23457 hypothetical protein YP_002734535.1 759210 R 546272 CDS YP_002734536.1 225686564 7671275 759545..759832 1 NC_012442.1 hypothetical protein 759832 7671275 BMEA_B0776 Brucella melitensis ATCC 23457 hypothetical protein YP_002734536.1 759545 D 546272 CDS YP_002734537.1 225686565 7671276 760136..760576 1 NC_012442.1 LysR family transcriptional regulator 760576 7671276 BMEA_B0777 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002734537.1 760136 D 546272 CDS YP_002734538.1 225686566 7671277 761172..762338 1 NC_012442.1 acyl-CoA dehydrogenase 762338 7671277 BMEA_B0778 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase YP_002734538.1 761172 D 546272 CDS YP_002734539.1 225686567 7671278 complement(762471..763271) 1 NC_012442.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 763271 nikE 7671278 nikE Brucella melitensis ATCC 23457 nickel transporter ATP-binding protein NikE YP_002734539.1 762471 R 546272 CDS YP_002734540.1 225686568 7671279 complement(763268..764056) 1 NC_012442.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 764056 nikD 7671279 nikD Brucella melitensis ATCC 23457 nickel transporter ATP-binding protein NikD YP_002734540.1 763268 R 546272 CDS YP_002734541.1 225686569 7671280 complement(764053..764925) 1 NC_012442.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 764925 nikC 7671280 nikC Brucella melitensis ATCC 23457 nickel transporter permease NikC YP_002734541.1 764053 R 546272 CDS YP_002734542.1 225686570 7671281 complement(764922..765866) 1 NC_012442.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 765866 nikB 7671281 nikB Brucella melitensis ATCC 23457 nickel transporter permease NikB YP_002734542.1 764922 R 546272 CDS YP_002734543.1 225686571 7671282 complement(765868..767448) 1 NC_012442.1 nickel ABC transporter periplasmic nickel-binding protein 767448 nikA 7671282 nikA Brucella melitensis ATCC 23457 nickel ABC transporter periplasmic nickel-binding protein YP_002734543.1 765868 R 546272 CDS YP_002734544.1 225686572 7671283 767715..768113 1 NC_012442.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 768113 nikR 7671283 nikR Brucella melitensis ATCC 23457 nickel responsive regulator YP_002734544.1 767715 D 546272 CDS YP_002734545.1 225686573 7671285 complement(769745..770587) 1 NC_012442.1 ABC transporter permease 770587 7671285 BMEA_B0786 Brucella melitensis ATCC 23457 ABC transporter permease YP_002734545.1 769745 R 546272 CDS YP_002734546.1 225686574 7671288 complement(772626..773807) 1 NC_012442.1 ABC transporter substrate-binding protein 773807 7671288 BMEA_B0789 Brucella melitensis ATCC 23457 ABC transporter substrate-binding protein YP_002734546.1 772626 R 546272 CDS YP_002734547.1 225686575 7671289 complement(773967..775469) 1 NC_012442.1 mannitol dehydrogenase domain -containing protein 775469 7671289 BMEA_B0790 Brucella melitensis ATCC 23457 mannitol dehydrogenase domain -containing protein YP_002734547.1 773967 R 546272 CDS YP_002734548.1 225686576 7671291 777200..777973 1 NC_012442.1 GntR family transcriptional regulator 777973 7671291 BMEA_B0792 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734548.1 777200 D 546272 CDS YP_002734549.1 225686577 7671292 778034..779239 1 NC_012442.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 779239 uxuA 7671292 uxuA Brucella melitensis ATCC 23457 mannonate dehydratase YP_002734549.1 778034 D 546272 CDS YP_002734550.1 225686578 7671293 complement(779423..782503) 1 NC_012442.1 putative multidrug efflux transporter protein 782503 7671293 BMEA_B0794 Brucella melitensis ATCC 23457 putative multidrug efflux transporter protein YP_002734550.1 779423 R 546272 CDS YP_002734551.1 225686579 7671294 complement(782526..783512) 1 NC_012442.1 RND family efflux transporter MFP subunit 783512 7671294 BMEA_B0795 Brucella melitensis ATCC 23457 RND family efflux transporter MFP subunit YP_002734551.1 782526 R 546272 CDS YP_002734552.1 225686580 7671295 783968..784369 1 NC_012442.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 784369 7671295 BMEA_B0796 Brucella melitensis ATCC 23457 camphor resistance protein CrcB YP_002734552.1 783968 D 546272 CDS YP_002734553.1 225686581 7671296 784357..784779 1 NC_012442.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 784779 7671296 BMEA_B0797 Brucella melitensis ATCC 23457 camphor resistance protein CrcB YP_002734553.1 784357 D 546272 CDS YP_002734554.1 225686582 7671297 784795..785154 1 NC_012442.1 hypothetical protein 785154 7671297 BMEA_B0798 Brucella melitensis ATCC 23457 hypothetical protein YP_002734554.1 784795 D 546272 CDS YP_002734555.1 225686583 7671298 complement(785209..785637) 1 NC_012442.1 transcriptional regulator MerR family protein 785637 7671298 BMEA_B0799 Brucella melitensis ATCC 23457 transcriptional regulator MerR family protein YP_002734555.1 785209 R 546272 CDS YP_002734556.1 225686584 7671299 complement(785898..786035) 1 NC_012442.1 hypothetical protein 786035 7671299 BMEA_B0800 Brucella melitensis ATCC 23457 hypothetical protein YP_002734556.1 785898 R 546272 CDS YP_002734557.1 225686585 7671300 786034..788883 1 NC_012442.1 peptidoglycan-binding domain 1 protein 788883 7671300 BMEA_B0801 Brucella melitensis ATCC 23457 peptidoglycan-binding domain 1 protein YP_002734557.1 786034 D 546272 CDS YP_002734558.1 225686586 7671301 789120..790070 1 NC_012442.1 hypothetical protein 790070 7671301 BMEA_B0802 Brucella melitensis ATCC 23457 hypothetical protein YP_002734558.1 789120 D 546272 CDS YP_002734559.1 225686587 7671302 790105..790896 1 NC_012442.1 hypothetical protein 790896 7671302 BMEA_B0803 Brucella melitensis ATCC 23457 hypothetical protein YP_002734559.1 790105 D 546272 CDS YP_002734560.1 225686588 7671303 complement(790994..791710) 1 NC_012442.1 hypothetical protein 791710 7671303 BMEA_B0804 Brucella melitensis ATCC 23457 hypothetical protein YP_002734560.1 790994 R 546272 CDS YP_002734561.1 225686589 7671304 complement(791707..794262) 1 NC_012442.1 hypothetical protein 794262 7671304 BMEA_B0805 Brucella melitensis ATCC 23457 hypothetical protein YP_002734561.1 791707 R 546272 CDS YP_002734562.1 225686590 7671305 complement(794272..794418) 1 NC_012442.1 hypothetical protein 794418 7671305 BMEA_B0806 Brucella melitensis ATCC 23457 hypothetical protein YP_002734562.1 794272 R 546272 CDS YP_002734563.1 225686591 7671306 complement(794514..795536) 1 NC_012442.1 hypothetical protein 795536 7671306 BMEA_B0807 Brucella melitensis ATCC 23457 hypothetical protein YP_002734563.1 794514 R 546272 CDS YP_002734564.1 225686592 7671307 complement(795735..795896) 1 NC_012442.1 hypothetical protein 795896 7671307 BMEA_B0808 Brucella melitensis ATCC 23457 hypothetical protein YP_002734564.1 795735 R 546272 CDS YP_002734565.1 225686593 7671308 796043..797011 1 NC_012442.1 2-nitropropane dioxygenase NPD 797011 7671308 BMEA_B0809 Brucella melitensis ATCC 23457 2-nitropropane dioxygenase NPD YP_002734565.1 796043 D 546272 CDS YP_002734566.1 225686594 7671309 797070..797207 1 NC_012442.1 hypothetical protein 797207 7671309 BMEA_B0810 Brucella melitensis ATCC 23457 hypothetical protein YP_002734566.1 797070 D 546272 CDS YP_002734567.1 225686595 7671311 798066..798788 1 NC_012442.1 hypothetical protein 798788 7671311 BMEA_B0812 Brucella melitensis ATCC 23457 hypothetical protein YP_002734567.1 798066 D 546272 CDS YP_002734568.1 225686596 7671312 complement(798795..799295) 1 NC_012442.1 hypothetical protein 799295 7671312 BMEA_B0813 Brucella melitensis ATCC 23457 hypothetical protein YP_002734568.1 798795 R 546272 CDS YP_002734569.1 225686597 7671313 799434..799550 1 NC_012442.1 hypothetical protein 799550 7671313 BMEA_B0814 Brucella melitensis ATCC 23457 hypothetical protein YP_002734569.1 799434 D 546272 CDS YP_002734570.1 225686598 7671314 complement(799846..800043) 1 NC_012442.1 hypothetical protein 800043 7671314 BMEA_B0815 Brucella melitensis ATCC 23457 hypothetical protein YP_002734570.1 799846 R 546272 CDS YP_002734571.1 225686599 7671315 800112..800267 1 NC_012442.1 hypothetical protein 800267 7671315 BMEA_B0816 Brucella melitensis ATCC 23457 hypothetical protein YP_002734571.1 800112 D 546272 CDS YP_002734572.1 225686600 7671316 complement(801061..801201) 1 NC_012442.1 hypothetical protein 801201 7671316 BMEA_B0817 Brucella melitensis ATCC 23457 hypothetical protein YP_002734572.1 801061 R 546272 CDS YP_002734573.1 225686601 7671317 801362..801994 1 NC_012442.1 hypothetical protein 801994 7671317 BMEA_B0818 Brucella melitensis ATCC 23457 hypothetical protein YP_002734573.1 801362 D 546272 CDS YP_002734574.1 225686602 7671318 802002..803528 1 NC_012442.1 type I restriction-modification system, M subunit 803528 hsdM 7671318 hsdM Brucella melitensis ATCC 23457 type I restriction-modification system, M subunit YP_002734574.1 802002 D 546272 CDS YP_002734575.1 225686603 7671319 803518..804741 1 NC_012442.1 type I restriction enzyme specificity protein 804741 7671319 BMEA_B0820 Brucella melitensis ATCC 23457 type I restriction enzyme specificity protein YP_002734575.1 803518 D 546272 CDS YP_002734576.1 225686604 7671320 804738..807707 1 NC_012442.1 type I site-specific deoxyribonuclease, HsdR family protein 807707 hsdR 7671320 hsdR Brucella melitensis ATCC 23457 type I site-specific deoxyribonuclease, HsdR family protein YP_002734576.1 804738 D 546272 CDS YP_002734577.1 225686605 7671321 807704..808444 1 NC_012442.1 hypothetical protein 808444 7671321 BMEA_B0822 Brucella melitensis ATCC 23457 hypothetical protein YP_002734577.1 807704 D 546272 CDS YP_002734578.1 225686606 7671322 808452..809381 1 NC_012442.1 hypothetical protein 809381 7671322 BMEA_B0823 Brucella melitensis ATCC 23457 hypothetical protein YP_002734578.1 808452 D 546272 CDS YP_002734579.1 225686607 7671323 809368..811263 1 NC_012442.1 hypothetical protein 811263 7671323 BMEA_B0824 Brucella melitensis ATCC 23457 hypothetical protein YP_002734579.1 809368 D 546272 CDS YP_002734580.1 225686608 7671324 811777..812145 1 NC_012442.1 transposase 812145 7671324 BMEA_B0825 Brucella melitensis ATCC 23457 transposase YP_002734580.1 811777 D 546272 CDS YP_002734581.1 225686609 7671325 812142..812534 1 NC_012442.1 transposase, IS4 812534 7671325 BMEA_B0826 Brucella melitensis ATCC 23457 transposase, IS4 YP_002734581.1 812142 D 546272 CDS YP_002734582.1 225686610 7671326 complement(812548..812682) 1 NC_012442.1 hypothetical protein 812682 7671326 BMEA_B0827 Brucella melitensis ATCC 23457 hypothetical protein YP_002734582.1 812548 R 546272 CDS YP_002734583.1 225686611 7671327 812944..813390 1 NC_012442.1 hypothetical protein 813390 7671327 BMEA_B0828 Brucella melitensis ATCC 23457 hypothetical protein YP_002734583.1 812944 D 546272 CDS YP_002734584.1 225686612 7671328 813501..815186 1 NC_012442.1 hypothetical protein 815186 7671328 BMEA_B0829 Brucella melitensis ATCC 23457 hypothetical protein YP_002734584.1 813501 D 546272 CDS YP_002734585.1 225686613 7671329 complement(815350..816804) 1 NC_012442.1 Putrescine aminotransferase 816804 7671329 BMEA_B0830 Brucella melitensis ATCC 23457 Putrescine aminotransferase YP_002734585.1 815350 R 546272 CDS YP_002734586.1 225686614 7671330 complement(816815..817825) 1 NC_012442.1 UDP-glucuronic acid decarboxylase 1 817825 7671330 BMEA_B0831 Brucella melitensis ATCC 23457 UDP-glucuronic acid decarboxylase 1 YP_002734586.1 816815 R 546272 CDS YP_002734587.1 225686615 7671331 complement(817874..818293) 1 NC_012442.1 hypothetical protein 818293 7671331 BMEA_B0832 Brucella melitensis ATCC 23457 hypothetical protein YP_002734587.1 817874 R 546272 CDS YP_002734588.1 225686616 7671332 complement(818325..819659) 1 NC_012442.1 FAD linked oxidase domain-containing protein 819659 7671332 BMEA_B0833 Brucella melitensis ATCC 23457 FAD linked oxidase domain-containing protein YP_002734588.1 818325 R 546272 CDS YP_002734589.1 225686617 7671333 complement(819659..821098) 1 NC_012442.1 hypothetical protein 821098 7671333 BMEA_B0834 Brucella melitensis ATCC 23457 hypothetical protein YP_002734589.1 819659 R 546272 CDS YP_002734590.1 225686618 7671334 complement(821721..822542) 1 NC_012442.1 Lactose phosphotransferase system repressor 822542 7671334 BMEA_B0835 Brucella melitensis ATCC 23457 Lactose phosphotransferase system repressor YP_002734590.1 821721 R 546272 CDS YP_002734591.1 225686619 7671335 complement(822750..823697) 1 NC_012442.1 rhizopine-binding protein 823697 7671335 BMEA_B0836 Brucella melitensis ATCC 23457 rhizopine-binding protein YP_002734591.1 822750 R 546272 CDS YP_002734592.1 225686620 7671336 complement(823864..824904) 1 NC_012442.1 hypothetical protein 824904 7671336 BMEA_B0837 Brucella melitensis ATCC 23457 hypothetical protein YP_002734592.1 823864 R 546272 CDS YP_002734593.1 225686621 7671337 complement(824928..826472) 1 NC_012442.1 Xylose import ATP-binding protein xylG 826472 7671337 BMEA_B0838 Brucella melitensis ATCC 23457 Xylose import ATP-binding protein xylG YP_002734593.1 824928 R 546272 CDS YP_002734594.1 225686622 7671338 complement(826469..827125) 1 NC_012442.1 hypothetical protein 827125 7671338 BMEA_B0839 Brucella melitensis ATCC 23457 hypothetical protein YP_002734594.1 826469 R 546272 CDS YP_002734595.1 225686623 7671339 827105..827272 1 NC_012442.1 hypothetical protein 827272 7671339 BMEA_B0840 Brucella melitensis ATCC 23457 hypothetical protein YP_002734595.1 827105 D 546272 CDS YP_002734596.1 225686624 7671340 complement(827225..827401) 1 NC_012442.1 hypothetical protein 827401 7671340 BMEA_B0841 Brucella melitensis ATCC 23457 hypothetical protein YP_002734596.1 827225 R 546272 CDS YP_002734597.1 225686625 7671341 827724..827876 1 NC_012442.1 hypothetical protein 827876 7671341 BMEA_B0842 Brucella melitensis ATCC 23457 hypothetical protein YP_002734597.1 827724 D 546272 CDS YP_002734598.1 225686626 7671342 827869..829422 1 NC_012442.1 carbohydrate kinase FGGY 829422 7671342 BMEA_B0843 Brucella melitensis ATCC 23457 carbohydrate kinase FGGY YP_002734598.1 827869 D 546272 CDS YP_002734599.1 225686627 7671343 829435..830943 1 NC_012442.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 830943 7671343 BMEA_B0844 Brucella melitensis ATCC 23457 glycerol-3-phosphate dehydrogenase YP_002734599.1 829435 D 546272 CDS YP_002734600.1 225686628 7671344 830951..831883 1 NC_012442.1 hypothetical protein 831883 7671344 BMEA_B0845 Brucella melitensis ATCC 23457 hypothetical protein YP_002734600.1 830951 D 546272 CDS YP_002734601.1 225686629 7671345 831911..832861 1 NC_012442.1 DeoR family transcriptional regulator 832861 7671345 BMEA_B0846 Brucella melitensis ATCC 23457 DeoR family transcriptional regulator YP_002734601.1 831911 D 546272 CDS YP_002734602.1 225686630 7671346 832949..833713 1 NC_012442.1 DeoR family transcriptional regulator 833713 7671346 BMEA_B0847 Brucella melitensis ATCC 23457 DeoR family transcriptional regulator YP_002734602.1 832949 D 546272 CDS YP_002734603.1 225686631 7671347 833726..834496 1 NC_012442.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 834496 tpiA 7671347 tpiA Brucella melitensis ATCC 23457 triosephosphate isomerase YP_002734603.1 833726 D 546272 CDS YP_002734604.1 225686632 7671348 834508..834963 1 NC_012442.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 834963 7671348 BMEA_B0849 Brucella melitensis ATCC 23457 ribose-5-phosphate isomerase B YP_002734604.1 834508 D 546272 CDS YP_002734605.1 225686633 7671349 complement(835030..836094) 1 NC_012442.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 836094 fba 7671349 fba Brucella melitensis ATCC 23457 fructose-1,6-bisphosphate aldolase YP_002734605.1 835030 R 546272 CDS YP_002734606.1 225686634 7671350 complement(836125..837147) 1 NC_012442.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 837147 7671350 BMEA_B0851 Brucella melitensis ATCC 23457 fructose-1,6-bisphosphatase YP_002734606.1 836125 R 546272 CDS YP_002734607.1 225686635 7671351 complement(837144..837383) 1 NC_012442.1 hypothetical protein 837383 7671351 BMEA_B0852 Brucella melitensis ATCC 23457 hypothetical protein YP_002734607.1 837144 R 546272 CDS YP_002734608.1 225686636 7671352 complement(837581..838198) 1 NC_012442.1 hypothetical protein 838198 7671352 BMEA_B0853 Brucella melitensis ATCC 23457 hypothetical protein YP_002734608.1 837581 R 546272 CDS YP_002734609.1 225686637 7671353 complement(838320..840146) 1 NC_012442.1 GTP-binding protein TypA 840146 typA 7671353 typA Brucella melitensis ATCC 23457 GTP-binding protein TypA YP_002734609.1 838320 R 546272 CDS YP_002734610.1 225686638 7671354 complement(840389..841786) 1 NC_012442.1 magnesium transporter 841786 mgtE 7671354 mgtE Brucella melitensis ATCC 23457 magnesium transporter YP_002734610.1 840389 R 546272 CDS YP_002734611.1 225686639 7671355 complement(841853..842017) 1 NC_012442.1 hypothetical protein 842017 7671355 BMEA_B0856 Brucella melitensis ATCC 23457 hypothetical protein YP_002734611.1 841853 R 546272 CDS YP_002734612.1 225686640 7671356 842112..844160 1 NC_012442.1 peptidyl-dipeptidase Dcp 844160 7671356 BMEA_B0857 Brucella melitensis ATCC 23457 peptidyl-dipeptidase Dcp YP_002734612.1 842112 D 546272 CDS YP_002734613.1 225686641 7671357 complement(844190..844543) 1 NC_012442.1 glyoxalase/bleomycin resistance protein/dioxygenase 844543 7671357 BMEA_B0858 Brucella melitensis ATCC 23457 glyoxalase/bleomycin resistance protein/dioxygenase YP_002734613.1 844190 R 546272 CDS YP_002734614.1 225686642 7671358 complement(844543..844749) 1 NC_012442.1 hypothetical protein 844749 7671358 BMEA_B0859 Brucella melitensis ATCC 23457 hypothetical protein YP_002734614.1 844543 R 546272 CDS YP_002734615.1 225686643 7671359 complement(844767..845765) 1 NC_012442.1 citrate lyase subunit beta 845765 7671359 BMEA_B0860 Brucella melitensis ATCC 23457 citrate lyase subunit beta YP_002734615.1 844767 R 546272 CDS YP_002734616.1 225686644 7671360 845796..846002 1 NC_012442.1 hypothetical protein 846002 7671360 BMEA_B0861 Brucella melitensis ATCC 23457 hypothetical protein YP_002734616.1 845796 D 546272 CDS YP_002734617.1 225686645 7671361 846067..846672 1 NC_012442.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 846672 leuD 7671361 leuD Brucella melitensis ATCC 23457 isopropylmalate isomerase small subunit YP_002734617.1 846067 D 546272 CDS YP_002734618.1 225686646 7671362 846758..847180 1 NC_012442.1 hypothetical protein 847180 7671362 BMEA_B0863 Brucella melitensis ATCC 23457 hypothetical protein YP_002734618.1 846758 D 546272 CDS YP_002734619.1 225686647 7671363 complement(847231..847653) 1 NC_012442.1 OsmC family protein 847653 7671363 BMEA_B0864 Brucella melitensis ATCC 23457 OsmC family protein YP_002734619.1 847231 R 546272 CDS YP_002734620.1 225686648 7671364 847859..848314 1 NC_012442.1 MarR family transcriptional regulator 848314 7671364 BMEA_B0865 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002734620.1 847859 D 546272 CDS YP_002734621.1 225686649 7671365 complement(848378..849412) 1 NC_012442.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 849412 asd 7671365 asd Brucella melitensis ATCC 23457 aspartate-semialdehyde dehydrogenase YP_002734621.1 848378 R 546272 CDS YP_002734622.1 225686650 7671366 849935..851833 1 NC_012442.1 major facilitator superfamily protein 851833 7671366 BMEA_B0867 Brucella melitensis ATCC 23457 major facilitator superfamily protein YP_002734622.1 849935 D 546272 CDS YP_002734623.1 225686651 7671367 complement(851891..852943) 1 NC_012442.1 methylated-DNA-protein-cysteine methyltransferase 852943 7671367 BMEA_B0868 Brucella melitensis ATCC 23457 methylated-DNA-protein-cysteine methyltransferase YP_002734623.1 851891 R 546272 CDS YP_002734624.1 225686652 7671368 complement(853084..854196) 1 NC_012442.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 854196 leuB 7671368 leuB Brucella melitensis ATCC 23457 3-isopropylmalate dehydrogenase YP_002734624.1 853084 R 546272 CDS YP_002734625.1 225686653 7671369 complement(854496..854690) 1 NC_012442.1 hypothetical protein 854690 7671369 BMEA_B0871 Brucella melitensis ATCC 23457 hypothetical protein YP_002734625.1 854496 R 546272 CDS YP_002734626.1 225686654 7671370 complement(854867..855571) 1 NC_012442.1 peptidase S16 lon domain-containing protein 855571 7671370 BMEA_B0872 Brucella melitensis ATCC 23457 peptidase S16 lon domain-containing protein YP_002734626.1 854867 R 546272 CDS YP_002734627.1 225686655 7671371 complement(855635..856609) 1 NC_012442.1 thioredoxin 856609 trx 7671371 trx Brucella melitensis ATCC 23457 thioredoxin YP_002734627.1 855635 R 546272 CDS YP_002734628.1 225686656 7671372 complement(856857..857399) 1 NC_012442.1 YbaK/prolyl-tRNA synthetase associated protein 857399 7671372 BMEA_B0874 Brucella melitensis ATCC 23457 YbaK/prolyl-tRNA synthetase associated protein YP_002734628.1 856857 R 546272 CDS YP_002734629.1 225686657 7671373 complement(857407..857598) 1 NC_012442.1 hypothetical protein 857598 7671373 BMEA_B0875 Brucella melitensis ATCC 23457 hypothetical protein YP_002734629.1 857407 R 546272 CDS YP_002734630.1 225686658 7671375 complement(857814..858323) 1 NC_012442.1 hypothetical protein 858323 7671375 BMEA_B0877 Brucella melitensis ATCC 23457 hypothetical protein YP_002734630.1 857814 R 546272 CDS YP_002734631.1 225686659 7671376 858395..858820 1 NC_012442.1 SEC-independent protein translocase protein TatC 858820 7671376 BMEA_B0879 Brucella melitensis ATCC 23457 SEC-independent protein translocase protein TatC YP_002734631.1 858395 D 546272 CDS YP_002734632.1 225686660 7671377 complement(858833..859909) 1 NC_012442.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 859909 7671377 BMEA_B0880 Brucella melitensis ATCC 23457 ornithine cyclodeaminase YP_002734632.1 858833 R 546272 CDS YP_002734633.1 225686661 7671378 complement(859948..860868) 1 NC_012442.1 arginase 860868 rocF 7671378 rocF Brucella melitensis ATCC 23457 arginase YP_002734633.1 859948 R 546272 CDS YP_002734634.1 225686662 7671379 860999..861436 1 NC_012442.1 hypothetical protein 861436 7671379 BMEA_B0882 Brucella melitensis ATCC 23457 hypothetical protein YP_002734634.1 860999 D 546272 CDS YP_002734635.1 225686663 7671380 complement(861474..862589) 1 NC_012442.1 NADH:flavin oxidoreductase/NADH oxidase 862589 7671380 BMEA_B0883 Brucella melitensis ATCC 23457 NADH:flavin oxidoreductase/NADH oxidase YP_002734635.1 861474 R 546272 CDS YP_002734636.1 225686664 7671381 complement(862633..862941) 1 NC_012442.1 regulatory protein ArsR 862941 7671381 BMEA_B0884 Brucella melitensis ATCC 23457 regulatory protein ArsR YP_002734636.1 862633 R 546272 CDS YP_002734637.1 225686665 7671383 complement(865557..866840) 1 NC_012442.1 FAD dependent oxidoreductase 866840 7671383 BMEA_B0886 Brucella melitensis ATCC 23457 FAD dependent oxidoreductase YP_002734637.1 865557 R 546272 CDS YP_002734638.1 225686666 7671384 complement(866940..867872) 1 NC_012442.1 hypothetical protein 867872 7671384 BMEA_B0887 Brucella melitensis ATCC 23457 hypothetical protein YP_002734638.1 866940 R 546272 CDS YP_002734639.1 225686667 7671386 868796..870328 1 NC_012442.1 aldehyde dehydrogenase family 7 member a1 870328 7671386 BMEA_B0890 Brucella melitensis ATCC 23457 aldehyde dehydrogenase family 7 member a1 YP_002734639.1 868796 D 546272 CDS YP_002734640.1 225686668 7671387 complement(870552..871436) 1 NC_012442.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 871436 purU 7671387 purU Brucella melitensis ATCC 23457 formyltetrahydrofolate deformylase YP_002734640.1 870552 R 546272 CDS YP_002734641.1 225686669 7671388 complement(871580..872308) 1 NC_012442.1 hypothetical protein 872308 7671388 BMEA_B0892 Brucella melitensis ATCC 23457 hypothetical protein YP_002734641.1 871580 R 546272 CDS YP_002734642.1 225686670 7671389 complement(872316..873482) 1 NC_012442.1 N-acetylglucosamine-6-phosphate deacetylase 873482 nagA 7671389 nagA Brucella melitensis ATCC 23457 N-acetylglucosamine-6-phosphate deacetylase YP_002734642.1 872316 R 546272 CDS YP_002734643.1 225686671 7671390 complement(873479..874510) 1 NC_012442.1 Sugar isomerase SIS 874510 7671390 BMEA_B0894 Brucella melitensis ATCC 23457 Sugar isomerase SIS YP_002734643.1 873479 R 546272 CDS YP_002734644.1 225686672 7671391 complement(874513..875280) 1 NC_012442.1 GntR family transcriptional regulator 875280 7671391 BMEA_B0895 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734644.1 874513 R 546272 CDS YP_002734645.1 225686673 7671392 complement(875383..878457) 1 NC_012442.1 acriflavin resistance protein 878457 7671392 BMEA_B0896 Brucella melitensis ATCC 23457 acriflavin resistance protein YP_002734645.1 875383 R 546272 CDS YP_002734646.1 225686674 7671393 complement(878454..879560) 1 NC_012442.1 RND family efflux transporter MFP subunit 879560 7671393 BMEA_B0897 Brucella melitensis ATCC 23457 RND family efflux transporter MFP subunit YP_002734646.1 878454 R 546272 CDS YP_002734647.1 225686675 7671394 complement(879557..880675) 1 NC_012442.1 RND family efflux transporter MFP subunit 880675 7671394 BMEA_B0898 Brucella melitensis ATCC 23457 RND family efflux transporter MFP subunit YP_002734647.1 879557 R 546272 CDS YP_002734648.1 225686676 7671395 complement(880806..880922) 1 NC_012442.1 hypothetical protein 880922 7671395 BMEA_B0899 Brucella melitensis ATCC 23457 hypothetical protein YP_002734648.1 880806 R 546272 CDS YP_002734649.1 225686677 7671396 complement(880961..881260) 1 NC_012442.1 hypothetical protein 881260 7671396 BMEA_B0900 Brucella melitensis ATCC 23457 hypothetical protein YP_002734649.1 880961 R 546272 CDS YP_002734650.1 225686678 7671397 complement(881257..883569) 1 NC_012442.1 oxidoreductase alpha, molybdopterin subunit 883569 7671397 BMEA_B0901 Brucella melitensis ATCC 23457 oxidoreductase alpha, molybdopterin subunit YP_002734650.1 881257 R 546272 CDS YP_002734651.1 225686679 7671398 883774..884919 1 NC_012442.1 FMN-dependent dehydrogenase 884919 7671398 BMEA_B0902 Brucella melitensis ATCC 23457 FMN-dependent dehydrogenase YP_002734651.1 883774 D 546272 CDS YP_002734652.1 225686680 7671399 885198..886052 1 NC_012442.1 outer surface protein 886052 7671399 BMEA_B0903 Brucella melitensis ATCC 23457 outer surface protein YP_002734652.1 885198 D 546272 CDS YP_002734653.1 225686681 7671400 complement(886200..886667) 1 NC_012442.1 Leucine-responsive regulatory protein 886667 7671400 BMEA_B0904 Brucella melitensis ATCC 23457 Leucine-responsive regulatory protein YP_002734653.1 886200 R 546272 CDS YP_002734654.1 225686682 7671401 886917..888107 1 NC_012442.1 alanine racemase 888107 alr 7671401 alr Brucella melitensis ATCC 23457 alanine racemase YP_002734654.1 886917 D 546272 CDS YP_002734655.1 225686683 7671402 888123..889373 1 NC_012442.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 889373 7671402 BMEA_B0906 Brucella melitensis ATCC 23457 D-amino acid dehydrogenase small subunit YP_002734655.1 888123 D 546272 CDS YP_002734656.1 225686684 7671403 complement(889416..889964) 1 NC_012442.1 hypothetical protein 889964 7671403 BMEA_B0907 Brucella melitensis ATCC 23457 hypothetical protein YP_002734656.1 889416 R 546272 CDS YP_002734657.1 225686685 7671404 complement(890091..890216) 1 NC_012442.1 hypothetical protein 890216 7671404 BMEA_B0908 Brucella melitensis ATCC 23457 hypothetical protein YP_002734657.1 890091 R 546272 CDS YP_002734658.1 225686686 7671405 890534..891439 1 NC_012442.1 Omega-amino acid--pyruvate aminotransferase 891439 7671405 BMEA_B0909 Brucella melitensis ATCC 23457 Omega-amino acid--pyruvate aminotransferase YP_002734658.1 890534 D 546272 CDS YP_002734659.1 225686687 7671406 complement(891510..892253) 1 NC_012442.1 histidine utilization repressor 892253 hutC 7671406 hutC Brucella melitensis ATCC 23457 histidine utilization repressor YP_002734659.1 891510 R 546272 CDS YP_002734660.1 225686688 7671407 complement(892265..893629) 1 NC_012442.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase 893629 hutF 7671407 hutF Brucella melitensis ATCC 23457 N-formimino-L-glutamate deiminase YP_002734660.1 892265 R 546272 CDS YP_002734661.1 225686689 7671408 complement(893642..893800) 1 NC_012442.1 hypothetical protein 893800 7671408 BMEA_B0912 Brucella melitensis ATCC 23457 hypothetical protein YP_002734661.1 893642 R 546272 CDS YP_002734662.1 225686690 7671409 893760..895931 1 NC_012442.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 895931 hutI 7671409 hutI Brucella melitensis ATCC 23457 imidazolonepropionase YP_002734662.1 893760 D 546272 CDS YP_002734663.1 225686691 7671411 896538..897338 1 NC_012442.1 N-formylglutamate amidohydrolase 897338 hutG 7671411 hutG Brucella melitensis ATCC 23457 N-formylglutamate amidohydrolase YP_002734663.1 896538 D 546272 CDS YP_002734664.1 225686692 7671412 897349..899022 1 NC_012442.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 899022 hutU 7671412 hutU Brucella melitensis ATCC 23457 urocanate hydratase YP_002734664.1 897349 D 546272 CDS YP_002734665.1 225686693 7671413 899029..899652 1 NC_012442.1 hypothetical protein 899652 7671413 BMEA_B0917 Brucella melitensis ATCC 23457 hypothetical protein YP_002734665.1 899029 D 546272 CDS YP_002734666.1 225686694 7671414 899740..900621 1 NC_012442.1 catalyzes the transamination of D-amino acids and their alpha-keto acids; D-amino acid aminotransferase 900621 7671414 BMEA_B0918 Brucella melitensis ATCC 23457 D-amino acid aminotransferase YP_002734666.1 899740 D 546272 CDS YP_002734667.1 225686695 7671415 complement(900772..901962) 1 NC_012442.1 monosaccharide-transporting ATPase 901962 7671415 BMEA_B0919 Brucella melitensis ATCC 23457 monosaccharide-transporting ATPase YP_002734667.1 900772 R 546272 CDS YP_002734668.1 225686696 7671416 complement(901962..903551) 1 NC_012442.1 L-arabinose transport ATP-binding protein araG 903551 7671416 BMEA_B0920 Brucella melitensis ATCC 23457 L-arabinose transport ATP-binding protein araG YP_002734668.1 901962 R 546272 CDS YP_002734669.1 225686697 7671417 903564..903704 1 NC_012442.1 hypothetical protein 903704 7671417 BMEA_B0921 Brucella melitensis ATCC 23457 hypothetical protein YP_002734669.1 903564 D 546272 CDS YP_002734670.1 225686698 7671419 complement(904906..905538) 1 NC_012442.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 905538 7671419 BMEA_B0923 Brucella melitensis ATCC 23457 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002734670.1 904906 R 546272 CDS YP_002734671.1 225686699 7671420 complement(905535..906464) 1 NC_012442.1 2-keto-3-deoxy-galactonokinase 906464 7671420 BMEA_B0924 Brucella melitensis ATCC 23457 2-keto-3-deoxy-galactonokinase YP_002734671.1 905535 R 546272 CDS YP_002734672.1 225686700 7671421 complement(906479..908284) 1 NC_012442.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase 908284 7671421 BMEA_B0925 Brucella melitensis ATCC 23457 dihydroxy-acid dehydratase YP_002734672.1 906479 R 546272 CDS YP_002734673.1 225686701 7671422 complement(908381..909316) 1 NC_012442.1 Galactose 1-dehydrogenase 909316 7671422 BMEA_B0926 Brucella melitensis ATCC 23457 Galactose 1-dehydrogenase YP_002734673.1 908381 R 546272 CDS YP_002734674.1 225686702 7671423 complement(909325..910317) 1 NC_012442.1 hypothetical protein 910317 7671423 BMEA_B0927 Brucella melitensis ATCC 23457 hypothetical protein YP_002734674.1 909325 R 546272 CDS YP_002734675.1 225686703 7671424 910587..910880 1 NC_012442.1 inner membrane ABC transporter permease YjfF 910880 7671424 BMEA_B0928 Brucella melitensis ATCC 23457 inner membrane ABC transporter permease YjfF YP_002734675.1 910587 D 546272 CDS YP_002734676.1 225686704 7671425 910905..911630 1 NC_012442.1 hypothetical protein 911630 7671425 BMEA_B0929 Brucella melitensis ATCC 23457 hypothetical protein YP_002734676.1 910905 D 546272 CDS YP_002734677.1 225686705 7671426 complement(911643..913337) 1 NC_012442.1 thiamine pyrophosphate protein 913337 7671426 BMEA_B0930 Brucella melitensis ATCC 23457 thiamine pyrophosphate protein YP_002734677.1 911643 R 546272 CDS YP_002734678.1 225686706 7671427 complement(913454..913582) 1 NC_012442.1 hypothetical protein 913582 7671427 BMEA_B0931 Brucella melitensis ATCC 23457 hypothetical protein YP_002734678.1 913454 R 546272 CDS YP_002734679.1 225686707 7671428 913586..913699 1 NC_012442.1 hypothetical protein 913699 7671428 BMEA_B0932 Brucella melitensis ATCC 23457 hypothetical protein YP_002734679.1 913586 D 546272 CDS YP_002734680.1 225686708 7671429 913744..915300 1 NC_012442.1 intracellular enzymes acting on low molecular weight D-amino acid amides, esters and oligopeptides containing D-amino acids; these proteases release the N-terminal D-amino acid from a peptide, and show higher affinity for D-Ala, D-Ser or D-Thr; no preference for the stereochemistry of the second amino acid; D-aminopeptidase 915300 7671429 BMEA_B0933 Brucella melitensis ATCC 23457 D-aminopeptidase YP_002734680.1 913744 D 546272 CDS YP_002734681.1 225686709 7671430 complement(915331..916350) 1 NC_012442.1 amino acid ABC transporter substrate-binding protein 916350 7671430 BMEA_B0934 Brucella melitensis ATCC 23457 amino acid ABC transporter substrate-binding protein YP_002734681.1 915331 R 546272 CDS YP_002734682.1 225686710 7671432 complement(919621..919779) 1 NC_012442.1 hypothetical protein 919779 7671432 BMEA_B0936 Brucella melitensis ATCC 23457 hypothetical protein YP_002734682.1 919621 R 546272 CDS YP_002734683.1 225686711 7671433 919778..920218 1 NC_012442.1 hypothetical protein 920218 7671433 BMEA_B0937 Brucella melitensis ATCC 23457 hypothetical protein YP_002734683.1 919778 D 546272 CDS YP_002734684.1 225686712 7671434 complement(920434..921348) 1 NC_012442.1 LysR family transcriptional regulator 921348 7671434 BMEA_B0938 Brucella melitensis ATCC 23457 LysR family transcriptional regulator YP_002734684.1 920434 R 546272 CDS YP_002734685.1 225686713 7671435 921613..922770 1 NC_012442.1 hypothetical protein 922770 7671435 BMEA_B0939 Brucella melitensis ATCC 23457 hypothetical protein YP_002734685.1 921613 D 546272 CDS YP_002734686.1 225686714 7671436 922783..923598 1 NC_012442.1 ABC transporter 923598 7671436 BMEA_B0940 Brucella melitensis ATCC 23457 ABC transporter YP_002734686.1 922783 D 546272 CDS YP_002734687.1 225686715 7671437 923591..924316 1 NC_012442.1 ABC transporter 924316 7671437 BMEA_B0941 Brucella melitensis ATCC 23457 ABC transporter YP_002734687.1 923591 D 546272 CDS YP_002734688.1 225686716 7671438 924321..925208 1 NC_012442.1 hypothetical protein 925208 7671438 BMEA_B0942 Brucella melitensis ATCC 23457 hypothetical protein YP_002734688.1 924321 D 546272 CDS YP_002734689.1 225686717 7671439 925210..926205 1 NC_012442.1 inner-membrane translocator 926205 7671439 BMEA_B0943 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002734689.1 925210 D 546272 CDS YP_002734690.1 225686718 7671440 926269..927867 1 NC_012442.1 choline dehydrogenase 927867 7671440 BMEA_B0944 Brucella melitensis ATCC 23457 choline dehydrogenase YP_002734690.1 926269 D 546272 CDS YP_002734691.1 225686719 7671441 927864..928007 1 NC_012442.1 hypothetical protein 928007 7671441 BMEA_B0945 Brucella melitensis ATCC 23457 hypothetical protein YP_002734691.1 927864 D 546272 CDS YP_002734692.1 225686720 7671442 928101..928937 1 NC_012442.1 lipoprotein, YaeC family protein 928937 7671442 BMEA_B0946 Brucella melitensis ATCC 23457 lipoprotein, YaeC family protein YP_002734692.1 928101 D 546272 CDS YP_002734693.1 225686721 7671443 929402..930460 1 NC_012442.1 methionine import ATP-binding protein MetN 930460 7671443 BMEA_B0947 Brucella melitensis ATCC 23457 methionine import ATP-binding protein MetN YP_002734693.1 929402 D 546272 CDS YP_002734694.1 225686722 7671444 930441..931106 1 NC_012442.1 D-methionine transport system permease metI 931106 7671444 BMEA_B0948 Brucella melitensis ATCC 23457 D-methionine transport system permease metI YP_002734694.1 930441 D 546272 CDS YP_002734695.1 225686723 7671445 complement(931119..931526) 1 NC_012442.1 glyoxalase/bleomycin resistance protein/dioxygenase 931526 7671445 BMEA_B0949 Brucella melitensis ATCC 23457 glyoxalase/bleomycin resistance protein/dioxygenase YP_002734695.1 931119 R 546272 CDS YP_002734696.1 225686724 7671446 complement(931618..932505) 1 NC_012442.1 TPR repeat-containing protein 932505 7671446 BMEA_B0950 Brucella melitensis ATCC 23457 TPR repeat-containing protein YP_002734696.1 931618 R 546272 CDS YP_002734697.1 225686725 7671447 932497..932760 1 NC_012442.1 hypothetical protein 932760 7671447 BMEA_B0951 Brucella melitensis ATCC 23457 hypothetical protein YP_002734697.1 932497 D 546272 CDS YP_002734698.1 225686726 7671448 complement(933044..933271) 1 NC_012442.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 933271 rpsU 7671448 rpsU Brucella melitensis ATCC 23457 30S ribosomal protein S21 YP_002734698.1 933044 R 546272 CDS YP_002734699.1 225686727 7671450 complement(934894..935370) 1 NC_012442.1 MaoC domain-containing protein dehydratase 935370 7671450 BMEA_B0954 Brucella melitensis ATCC 23457 MaoC domain-containing protein dehydratase YP_002734699.1 934894 R 546272 CDS YP_002734700.1 225686728 7671451 complement(935445..936116) 1 NC_012442.1 HAD-superfamily hydrolase 936116 7671451 BMEA_B0955 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002734700.1 935445 R 546272 CDS YP_002734701.1 225686729 7671452 936312..937628 1 NC_012442.1 homoserine dehydrogenase NAD-binding 937628 7671452 BMEA_B0956 Brucella melitensis ATCC 23457 homoserine dehydrogenase NAD-binding YP_002734701.1 936312 D 546272 CDS YP_002734702.1 225686730 7671453 complement(937714..939114) 1 NC_012442.1 hypothetical protein 939114 7671453 BMEA_B0957 Brucella melitensis ATCC 23457 hypothetical protein YP_002734702.1 937714 R 546272 CDS YP_002734703.1 225686731 7671454 complement(939127..939546) 1 NC_012442.1 hypothetical protein 939546 7671454 BMEA_B0958 Brucella melitensis ATCC 23457 hypothetical protein YP_002734703.1 939127 R 546272 CDS YP_002734704.1 225686732 7671455 complement(939546..940847) 1 NC_012442.1 alanine dehydrogenase/PNT domain-containing protein 940847 7671455 BMEA_B0959 Brucella melitensis ATCC 23457 alanine dehydrogenase/PNT domain-containing protein YP_002734704.1 939546 R 546272 CDS YP_002734705.1 225686733 7671456 complement(941071..941295) 1 NC_012442.1 aa3 type cytochrome c oxidase subunit IV 941295 7671456 BMEA_B0960 Brucella melitensis ATCC 23457 aa3 type cytochrome c oxidase subunit IV YP_002734705.1 941071 R 546272 CDS YP_002734706.1 225686734 7671458 complement(942516..943733) 1 NC_012442.1 6-aminohexanoate-dimer hydrolase 943733 7671458 BMEA_B0962 Brucella melitensis ATCC 23457 6-aminohexanoate-dimer hydrolase YP_002734706.1 942516 R 546272 CDS YP_002734707.1 225686735 7671459 complement(943985..946282) 1 NC_012442.1 GGDEF domain-containing protein 946282 7671459 BMEA_B0963 Brucella melitensis ATCC 23457 GGDEF domain-containing protein YP_002734707.1 943985 R 546272 CDS YP_002734708.1 225686736 7671460 complement(946527..946667) 1 NC_012442.1 hypothetical protein 946667 7671460 BMEA_B0964 Brucella melitensis ATCC 23457 hypothetical protein YP_002734708.1 946527 R 546272 CDS YP_002734709.1 225686737 7671461 complement(946648..947397) 1 NC_012442.1 glucose 1-dehydrogenase 3 947397 7671461 BMEA_B0965 Brucella melitensis ATCC 23457 glucose 1-dehydrogenase 3 YP_002734709.1 946648 R 546272 CDS YP_002734710.1 225686738 7671462 947632..948405 1 NC_012442.1 peptidase C26 948405 7671462 BMEA_B0966 Brucella melitensis ATCC 23457 peptidase C26 YP_002734710.1 947632 D 546272 CDS YP_002734711.1 225686739 7671463 complement(948555..949529) 1 NC_012442.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding 949529 7671463 BMEA_B0967 Brucella melitensis ATCC 23457 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding YP_002734711.1 948555 R 546272 CDS YP_002734712.1 225686740 7671464 complement(949615..950634) 1 NC_012442.1 HTH-type transcriptional repressor PurR 950634 7671464 BMEA_B0968 Brucella melitensis ATCC 23457 HTH-type transcriptional repressor PurR YP_002734712.1 949615 R 546272 CDS YP_002734713.1 225686741 7671465 complement(950781..951038) 1 NC_012442.1 MarR family transcriptional regulator 951038 7671465 BMEA_B0969 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002734713.1 950781 R 546272 CDS YP_002734714.1 225686742 7671466 complement(951045..951272) 1 NC_012442.1 MarR family transcriptional regulator 951272 7671466 BMEA_B0970 Brucella melitensis ATCC 23457 MarR family transcriptional regulator YP_002734714.1 951045 R 546272 CDS YP_002734715.1 225686743 7671467 951451..952221 1 NC_012442.1 creatininase 952221 7671467 BMEA_B0971 Brucella melitensis ATCC 23457 creatininase YP_002734715.1 951451 D 546272 CDS YP_002734716.1 225686744 7671468 952457..953590 1 NC_012442.1 cobalamin synthesis protein P47K 953590 7671468 BMEA_B0972 Brucella melitensis ATCC 23457 cobalamin synthesis protein P47K YP_002734716.1 952457 D 546272 CDS YP_002734717.1 225686745 7671469 953709..954683 1 NC_012442.1 WD-repeat family protein 954683 7671469 BMEA_B0973 Brucella melitensis ATCC 23457 WD-repeat family protein YP_002734717.1 953709 D 546272 CDS YP_002734718.1 225686746 7671470 complement(954888..955754) 1 NC_012442.1 hypothetical protein 955754 7671470 BMEA_B0974 Brucella melitensis ATCC 23457 hypothetical protein YP_002734718.1 954888 R 546272 CDS YP_002734719.1 225686747 7671471 956177..957136 1 NC_012442.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 957136 7671471 BMEA_B0975 Brucella melitensis ATCC 23457 putative sulfite oxidase subunit YedY YP_002734719.1 956177 D 546272 CDS YP_002734720.1 225686748 7671472 957138..957800 1 NC_012442.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 957800 7671472 BMEA_B0976 Brucella melitensis ATCC 23457 putative sulfite oxidase subunit YedZ YP_002734720.1 957138 D 546272 CDS YP_002734721.1 225686749 7671473 complement(958008..958352) 1 NC_012442.1 hypothetical protein 958352 7671473 BMEA_B0977 Brucella melitensis ATCC 23457 hypothetical protein YP_002734721.1 958008 R 546272 CDS YP_002734722.1 225686750 7671474 complement(958427..959380) 1 NC_012442.1 monosaccharide-transporting ATPase 959380 7671474 BMEA_B0978 Brucella melitensis ATCC 23457 monosaccharide-transporting ATPase YP_002734722.1 958427 R 546272 CDS YP_002734723.1 225686751 7671475 complement(959377..960336) 1 NC_012442.1 inner-membrane translocator 960336 7671475 BMEA_B0979 Brucella melitensis ATCC 23457 inner-membrane translocator YP_002734723.1 959377 R 546272 CDS YP_002734724.1 225686752 7671477 complement(961774..962943) 1 NC_012442.1 rhizopine-binding protein 962943 7671477 BMEA_B0981 Brucella melitensis ATCC 23457 rhizopine-binding protein YP_002734724.1 961774 R 546272 CDS YP_002734725.1 225686753 7671478 963245..964039 1 NC_012442.1 Pectin degradation repressor protein kdgR 964039 7671478 BMEA_B0982 Brucella melitensis ATCC 23457 Pectin degradation repressor protein kdgR YP_002734725.1 963245 D 546272 CDS YP_002734726.1 225686754 7671479 complement(964133..965314) 1 NC_012442.1 hypothetical protein 965314 7671479 BMEA_B0983 Brucella melitensis ATCC 23457 hypothetical protein YP_002734726.1 964133 R 546272 CDS YP_002734727.1 225686755 7671480 complement(965482..967512) 1 NC_012442.1 TonB-dependent copper receptor 967512 7671480 BMEA_B0984 Brucella melitensis ATCC 23457 TonB-dependent copper receptor YP_002734727.1 965482 R 546272 CDS YP_002734728.1 225686756 7671481 complement(967609..968016) 1 NC_012442.1 hypothetical protein 968016 7671481 BMEA_B0985 Brucella melitensis ATCC 23457 hypothetical protein YP_002734728.1 967609 R 546272 CDS YP_002734729.1 225686757 7671482 complement(968169..968555) 1 NC_012442.1 glyoxalase domain-containing protein 5 968555 7671482 BMEA_B0986 Brucella melitensis ATCC 23457 glyoxalase domain-containing protein 5 YP_002734729.1 968169 R 546272 CDS YP_002734730.1 225686758 7671483 complement(968738..969343) 1 NC_012442.1 glutathione S-transferase 969343 7671483 BMEA_B0987 Brucella melitensis ATCC 23457 glutathione S-transferase YP_002734730.1 968738 R 546272 CDS YP_002734731.1 225686759 7671484 complement(969447..970748) 1 NC_012442.1 hypothetical protein 970748 7671484 BMEA_B0988 Brucella melitensis ATCC 23457 hypothetical protein YP_002734731.1 969447 R 546272 CDS YP_002734732.1 225686760 7671486 complement(972232..973464) 1 NC_012442.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 973464 7671486 BMEA_B0990 Brucella melitensis ATCC 23457 hydroxyglutarate oxidase YP_002734732.1 972232 R 546272 CDS YP_002734733.1 225686761 7671487 973620..974618 1 NC_012442.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 974618 7671487 BMEA_B0991 Brucella melitensis ATCC 23457 DNA polymerase III subunit epsilon YP_002734733.1 973620 D 546272 CDS YP_002734734.1 225686762 7671488 complement(974694..976082) 1 NC_012442.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 976082 7671488 BMEA_B0992 Brucella melitensis ATCC 23457 amidase YP_002734734.1 974694 R 546272 CDS YP_002734735.1 225686763 7671489 complement(976096..976944) 1 NC_012442.1 oligopeptide transport ATP-binding protein oppF 976944 7671489 BMEA_B0993 Brucella melitensis ATCC 23457 oligopeptide transport ATP-binding protein oppF YP_002734735.1 976096 R 546272 CDS YP_002734736.1 225686764 7671490 complement(976941..977966) 1 NC_012442.1 peptide ABC transporter ATPase 977966 7671490 BMEA_B0994 Brucella melitensis ATCC 23457 peptide ABC transporter ATPase YP_002734736.1 976941 R 546272 CDS YP_002734737.1 225686765 7671491 complement(977963..978823) 1 NC_012442.1 dipeptide transport system permease DppC 978823 7671491 BMEA_B0995 Brucella melitensis ATCC 23457 dipeptide transport system permease DppC YP_002734737.1 977963 R 546272 CDS YP_002734738.1 225686766 7671492 complement(978820..979773) 1 NC_012442.1 hypothetical protein 979773 7671492 BMEA_B0996 Brucella melitensis ATCC 23457 hypothetical protein YP_002734738.1 978820 R 546272 CDS YP_002734739.1 225686767 7671493 complement(979871..981349) 1 NC_012442.1 glutathione-binding protein GsiB 981349 7671493 BMEA_B0997 Brucella melitensis ATCC 23457 glutathione-binding protein GsiB YP_002734739.1 979871 R 546272 CDS YP_002734740.1 225686768 7671494 complement(981372..982130) 1 NC_012442.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 982130 fabG 7671494 fabG Brucella melitensis ATCC 23457 3-ketoacyl-ACP reductase YP_002734740.1 981372 R 546272 CDS YP_002734741.1 225686769 7671495 complement(982165..983652) 1 NC_012442.1 aldehyde dehydrogenase 983652 7671495 BMEA_B0999 Brucella melitensis ATCC 23457 aldehyde dehydrogenase YP_002734741.1 982165 R 546272 CDS YP_002734742.1 225686770 7671496 complement(983636..984322) 1 NC_012442.1 GntR family transcriptional regulator 984322 7671496 BMEA_B1000 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734742.1 983636 R 546272 CDS YP_002734743.1 225686771 7671497 complement(984422..984568) 1 NC_012442.1 hypothetical protein 984568 7671497 BMEA_B1001 Brucella melitensis ATCC 23457 hypothetical protein YP_002734743.1 984422 R 546272 CDS YP_002734744.1 225686772 7671498 984692..986071 1 NC_012442.1 drug resistance transporter, EmrB/QacA subfamily protein 986071 7671498 BMEA_B1002 Brucella melitensis ATCC 23457 drug resistance transporter, EmrB/QacA subfamily protein YP_002734744.1 984692 D 546272 CDS YP_002734745.1 225686773 7671500 986465..987532 1 NC_012442.1 hypothetical protein 987532 7671500 BMEA_B1004 Brucella melitensis ATCC 23457 hypothetical protein YP_002734745.1 986465 D 546272 CDS YP_002734746.1 225686774 7671501 complement(987586..987930) 1 NC_012442.1 endoribonuclease L-PSP 987930 7671501 BMEA_B1005 Brucella melitensis ATCC 23457 endoribonuclease L-PSP YP_002734746.1 987586 R 546272 CDS YP_002734747.1 225686775 7671502 988013..988237 1 NC_012442.1 hypothetical protein 988237 7671502 BMEA_B1006 Brucella melitensis ATCC 23457 hypothetical protein YP_002734747.1 988013 D 546272 CDS YP_002734748.1 225686776 7671503 988238..988372 1 NC_012442.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 988372 rpmH 7671503 rpmH Brucella melitensis ATCC 23457 50S ribosomal protein L34 YP_002734748.1 988238 D 546272 CDS YP_002734749.1 225686777 7671504 988422..988847 1 NC_012442.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 988847 rnpA 7671504 rnpA Brucella melitensis ATCC 23457 ribonuclease P YP_002734749.1 988422 D 546272 CDS YP_002734750.1 225686778 7671505 988837..990669 1 NC_012442.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 990669 7671505 BMEA_B1009 Brucella melitensis ATCC 23457 putative inner membrane protein translocase component YidC YP_002734750.1 988837 D 546272 CDS YP_002734751.1 225686779 7671506 990711..991514 1 NC_012442.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 991514 engB 7671506 engB Brucella melitensis ATCC 23457 ribosome biogenesis GTP-binding protein YsxC YP_002734751.1 990711 D 546272 CDS YP_002734752.1 225686780 7671507 991685..992575 1 NC_012442.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 992575 argB 7671507 argB Brucella melitensis ATCC 23457 acetylglutamate kinase YP_002734752.1 991685 D 546272 CDS YP_002734753.1 225686781 7671508 992649..993353 1 NC_012442.1 pyrimidine 5'-nucleotidase 993353 7671508 BMEA_B1012 Brucella melitensis ATCC 23457 pyrimidine 5'-nucleotidase YP_002734753.1 992649 D 546272 CDS YP_002734754.1 225686782 7671509 complement(993415..994245) 1 NC_012442.1 hypothetical protein 994245 7671509 BMEA_B1013 Brucella melitensis ATCC 23457 hypothetical protein YP_002734754.1 993415 R 546272 CDS YP_002734755.1 225686783 7671510 994462..995316 1 NC_012442.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 995316 dapD 7671510 dapD Brucella melitensis ATCC 23457 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002734755.1 994462 D 546272 CDS YP_002734756.1 225686784 7671511 complement(995460..996014) 1 NC_012442.1 transglutaminase family protein cysteine peptidase BTLCP 996014 7671511 BMEA_B1015 Brucella melitensis ATCC 23457 transglutaminase family protein cysteine peptidase BTLCP YP_002734756.1 995460 R 546272 CDS YP_002734757.1 225686785 7671512 996299..997486 1 NC_012442.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 997486 dapE 7671512 dapE Brucella melitensis ATCC 23457 succinyl-diaminopimelate desuccinylase YP_002734757.1 996299 D 546272 CDS YP_002734758.1 225686786 7671513 997549..998154 1 NC_012442.1 hypothetical protein 998154 7671513 BMEA_B1017 Brucella melitensis ATCC 23457 hypothetical protein YP_002734758.1 997549 D 546272 CDS YP_002734759.1 225686787 7671514 complement(998329..999084) 1 NC_012442.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 999084 truA 7671514 truA Brucella melitensis ATCC 23457 tRNA pseudouridine synthase A YP_002734759.1 998329 R 546272 CDS YP_002734760.1 225686788 7671515 complement(999088..1000008) 1 NC_012442.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1000008 fmt 7671515 fmt Brucella melitensis ATCC 23457 methionyl-tRNA formyltransferase YP_002734760.1 999088 R 546272 CDS YP_002734761.1 225686789 7671516 complement(1000008..1000571) 1 NC_012442.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1000571 def 7671516 def Brucella melitensis ATCC 23457 peptide deformylase YP_002734761.1 1000008 R 546272 CDS YP_002734762.1 225686790 7671517 1000638..1001861 1 NC_012442.1 hypothetical protein 1001861 7671517 BMEA_B1021 Brucella melitensis ATCC 23457 hypothetical protein YP_002734762.1 1000638 D 546272 CDS YP_002734763.1 225686791 7671518 complement(1002082..1002387) 1 NC_012442.1 Selenoprotein W-related family protein 1002387 7671518 BMEA_B1022 Brucella melitensis ATCC 23457 Selenoprotein W-related family protein YP_002734763.1 1002082 R 546272 CDS YP_002734764.1 225686792 7671519 1002496..1002777 1 NC_012442.1 GIY-YIG catalytic domain-containing protein 1002777 7671519 BMEA_B1023 Brucella melitensis ATCC 23457 GIY-YIG catalytic domain-containing protein YP_002734764.1 1002496 D 546272 CDS YP_002734765.1 225686793 7671520 complement(1003025..1004833) 1 NC_012442.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1004833 lepA 7671520 lepA Brucella melitensis ATCC 23457 GTP-binding protein LepA YP_002734765.1 1003025 R 546272 CDS YP_002734766.1 225686794 7671521 complement(1004830..1004961) 1 NC_012442.1 hypothetical protein 1004961 7671521 BMEA_B1025 Brucella melitensis ATCC 23457 hypothetical protein YP_002734766.1 1004830 R 546272 CDS YP_002734767.1 225686795 7671522 1004997..1005983 1 NC_012442.1 NADH-ubiquinone oxidoreductase 1005983 7671522 BMEA_B1026 Brucella melitensis ATCC 23457 NADH-ubiquinone oxidoreductase YP_002734767.1 1004997 D 546272 CDS YP_002734768.1 225686796 7671523 complement(1006084..1006890) 1 NC_012442.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 1006890 7671523 BMEA_B1027 Brucella melitensis ATCC 23457 UDP pyrophosphate phosphatase YP_002734768.1 1006084 R 546272 CDS YP_002734769.1 225686797 7671524 complement(1006895..1007098) 1 NC_012442.1 hypothetical protein 1007098 7671524 BMEA_B1028 Brucella melitensis ATCC 23457 hypothetical protein YP_002734769.1 1006895 R 546272 CDS YP_002734770.1 225686798 7671525 1007146..1007838 1 NC_012442.1 hypothetical protein 1007838 7671525 BMEA_B1029 Brucella melitensis ATCC 23457 hypothetical protein YP_002734770.1 1007146 D 546272 CDS YP_002734771.1 225686799 7671526 1007819..1009015 1 NC_012442.1 hypothetical protein 1009015 7671526 BMEA_B1030 Brucella melitensis ATCC 23457 hypothetical protein YP_002734771.1 1007819 D 546272 CDS YP_002734772.1 225686800 7671527 1009017..1009886 1 NC_012442.1 NAD-dependent epimerase/dehydratase 1009886 7671527 BMEA_B1031 Brucella melitensis ATCC 23457 NAD-dependent epimerase/dehydratase YP_002734772.1 1009017 D 546272 CDS YP_002734773.1 225686801 7671528 1009887..1010909 1 NC_012442.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1010909 mepA 7671528 mepA Brucella melitensis ATCC 23457 penicillin-insensitive murein endopeptidase YP_002734773.1 1009887 D 546272 CDS YP_002734774.1 225686802 7671529 1011062..1011439 1 NC_012442.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1011439 mgsA 7671529 mgsA Brucella melitensis ATCC 23457 methylglyoxal synthase YP_002734774.1 1011062 D 546272 CDS YP_002734775.1 225686803 7671530 1011520..1012551 1 NC_012442.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1012551 glk 7671530 glk Brucella melitensis ATCC 23457 glucokinase YP_002734775.1 1011520 D 546272 CDS YP_002734776.1 225686804 7671531 1012778..1014607 1 NC_012442.1 ABC transporter 1014607 7671531 BMEA_B1035 Brucella melitensis ATCC 23457 ABC transporter YP_002734776.1 1012778 D 546272 CDS YP_002734777.1 225686805 7671532 1014604..1015443 1 NC_012442.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1015443 dapB 7671532 dapB Brucella melitensis ATCC 23457 dihydrodipicolinate reductase YP_002734777.1 1014604 D 546272 CDS YP_002734778.1 225686806 7671533 1015480..1016100 1 NC_012442.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1016100 7671533 BMEA_B1037 Brucella melitensis ATCC 23457 phosphoglyceromutase YP_002734778.1 1015480 D 546272 CDS YP_002734779.1 225686807 7671536 1018780..1019403 1 NC_012442.1 cob(II)yrinic acid a,c-diamide reductase 1019403 bluB 7671536 bluB Brucella melitensis ATCC 23457 cob(II)yrinic acid a,c-diamide reductase YP_002734779.1 1018780 D 546272 CDS YP_002734780.1 225686808 7671537 1019600..1020046 1 NC_012442.1 universal stress protein 1020046 7671537 BMEA_B1041 Brucella melitensis ATCC 23457 universal stress protein YP_002734780.1 1019600 D 546272 CDS YP_002734781.1 225686809 7671538 complement(1020163..1020381) 1 NC_012442.1 hypothetical protein 1020381 7671538 BMEA_B1043 Brucella melitensis ATCC 23457 hypothetical protein YP_002734781.1 1020163 R 546272 CDS YP_002734782.1 225686810 7671539 1020535..1020966 1 NC_012442.1 YhhN family protein 1020966 7671539 BMEA_B1044 Brucella melitensis ATCC 23457 YhhN family protein YP_002734782.1 1020535 D 546272 CDS YP_002734783.1 225686811 7671541 1022526..1023383 1 NC_012442.1 endonuclease/exonuclease/phosphatase 1023383 7671541 BMEA_B1046 Brucella melitensis ATCC 23457 endonuclease/exonuclease/phosphatase YP_002734783.1 1022526 D 546272 CDS YP_002734784.1 225686812 7671542 complement(1023393..1024853) 1 NC_012442.1 cardiolipin synthetase 1024853 7671542 BMEA_B1047 Brucella melitensis ATCC 23457 cardiolipin synthetase YP_002734784.1 1023393 R 546272 CDS YP_002734785.1 225686813 7671543 1025025..1025588 1 NC_012442.1 hypothetical protein 1025588 7671543 BMEA_B1048 Brucella melitensis ATCC 23457 hypothetical protein YP_002734785.1 1025025 D 546272 CDS YP_002734786.1 225686814 7671544 complement(1025600..1025713) 1 NC_012442.1 hypothetical protein 1025713 7671544 BMEA_B1049 Brucella melitensis ATCC 23457 hypothetical protein YP_002734786.1 1025600 R 546272 CDS YP_002734787.1 225686815 7671545 1025749..1027326 1 NC_012442.1 peptide chain release factor 3 1027326 prfC 7671545 prfC Brucella melitensis ATCC 23457 peptide chain release factor 3 YP_002734787.1 1025749 D 546272 CDS YP_002734788.1 225686816 7671546 complement(1027323..1028543) 1 NC_012442.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1028543 coaBC 7671546 coaBC Brucella melitensis ATCC 23457 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002734788.1 1027323 R 546272 CDS YP_002734789.1 225686817 7671547 complement(1028574..1030157) 1 NC_012442.1 2-polyprenylphenol 6-hydroxylase 1030157 ubiB 7671547 ubiB Brucella melitensis ATCC 23457 2-polyprenylphenol 6-hydroxylase YP_002734789.1 1028574 R 546272 CDS YP_002734790.1 225686818 7671548 complement(1030206..1031015) 1 NC_012442.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1031015 ubiE 7671548 ubiE Brucella melitensis ATCC 23457 ubiquinone/menaquinone biosynthesis methyltransferase YP_002734790.1 1030206 R 546272 CDS YP_002734791.1 225686819 7671549 1031326..1031952 1 NC_012442.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1031952 upp 7671549 upp Brucella melitensis ATCC 23457 uracil phosphoribosyltransferase YP_002734791.1 1031326 D 546272 CDS YP_002734792.1 225686820 7671550 1032063..1032269 1 NC_012442.1 hypothetical protein 1032269 7671550 BMEA_B1055 Brucella melitensis ATCC 23457 hypothetical protein YP_002734792.1 1032063 D 546272 CDS YP_002734793.1 225686821 7671551 complement(1032282..1032938) 1 NC_012442.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1032938 msrA 7671551 msrA Brucella melitensis ATCC 23457 methionine sulfoxide reductase A YP_002734793.1 1032282 R 546272 CDS YP_002734794.1 225686822 7671552 complement(1032961..1033284) 1 NC_012442.1 hypothetical protein 1033284 7671552 BMEA_B1057 Brucella melitensis ATCC 23457 hypothetical protein YP_002734794.1 1032961 R 546272 CDS YP_002734795.1 225686823 7671553 complement(1033262..1033414) 1 NC_012442.1 hypothetical protein 1033414 7671553 BMEA_B1058 Brucella melitensis ATCC 23457 hypothetical protein YP_002734795.1 1033262 R 546272 CDS YP_002734796.1 225686824 7671555 complement(1033955..1034863) 1 NC_012442.1 transposase orfB, IS3 family element 1034863 7671555 BMEA_B1060 Brucella melitensis ATCC 23457 transposase orfB, IS3 family element YP_002734796.1 1033955 R 546272 CDS YP_002734797.1 225686825 7671556 complement(1034860..1035141) 1 NC_012442.1 transposase insN for insertion sequence element IS911 1035141 7671556 BMEA_B1061 Brucella melitensis ATCC 23457 transposase insN for insertion sequence element IS911 YP_002734797.1 1034860 R 546272 CDS YP_002734798.1 225686826 7671557 1035559..1036077 1 NC_012442.1 D-lactate dehydrogenase 1036077 7671557 BMEA_B1063 Brucella melitensis ATCC 23457 D-lactate dehydrogenase YP_002734798.1 1035559 D 546272 CDS YP_002734799.1 225686827 7671558 1036508..1036792 1 NC_012442.1 transcriptional modulator of MazE/toxin, MazF 1036792 7671558 BMEA_B1064 Brucella melitensis ATCC 23457 transcriptional modulator of MazE/toxin, MazF YP_002734799.1 1036508 D 546272 CDS YP_002734800.1 225686828 7671559 complement(1036801..1037118) 1 NC_012442.1 hypothetical protein 1037118 7671559 BMEA_B1065 Brucella melitensis ATCC 23457 hypothetical protein YP_002734800.1 1036801 R 546272 CDS YP_002734801.1 225686829 7671560 complement(1037291..1038547) 1 NC_012442.1 hypothetical protein 1038547 7671560 BMEA_B1066 Brucella melitensis ATCC 23457 hypothetical protein YP_002734801.1 1037291 R 546272 CDS YP_002734802.1 225686830 7671561 complement(1038642..1039301) 1 NC_012442.1 putative L-fuculose-1-phosphate aldolase subunit P 1039301 7671561 BMEA_B1067 Brucella melitensis ATCC 23457 putative L-fuculose-1-phosphate aldolase subunit P YP_002734802.1 1038642 R 546272 CDS YP_002734803.1 225686831 7671563 complement(1041326..1042531) 1 NC_012442.1 glutamate-1-semialdehyde 2,1-aminomutase 1042531 7671563 BMEA_B1069 Brucella melitensis ATCC 23457 glutamate-1-semialdehyde 2,1-aminomutase YP_002734803.1 1041326 R 546272 CDS YP_002734804.1 225686832 7671564 1042647..1043936 1 NC_012442.1 ABC transporter ATP-binding protein 1043936 7671564 BMEA_B1070 Brucella melitensis ATCC 23457 ABC transporter ATP-binding protein YP_002734804.1 1042647 D 546272 CDS YP_002734805.1 225686833 7671565 1043992..1044807 1 NC_012442.1 ABC transporter permease 1044807 7671565 BMEA_B1071 Brucella melitensis ATCC 23457 ABC transporter permease YP_002734805.1 1043992 D 546272 CDS YP_002734806.1 225686834 7671566 1044804..1045607 1 NC_012442.1 ABC transporter permease 1045607 7671566 BMEA_B1072 Brucella melitensis ATCC 23457 ABC transporter permease YP_002734806.1 1044804 D 546272 CDS YP_002734807.1 225686835 7671567 1045600..1046682 1 NC_012442.1 ABC transporter substrate-binding protein 1046682 7671567 BMEA_B1073 Brucella melitensis ATCC 23457 ABC transporter substrate-binding protein YP_002734807.1 1045600 D 546272 CDS YP_002734808.1 225686836 7671568 complement(1046728..1048146) 1 NC_012442.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1048146 7671568 BMEA_B1074 Brucella melitensis ATCC 23457 amidase YP_002734808.1 1046728 R 546272 CDS YP_002734809.1 225686837 7671569 complement(1048161..1049033) 1 NC_012442.1 hypothetical protein 1049033 7671569 BMEA_B1075 Brucella melitensis ATCC 23457 hypothetical protein YP_002734809.1 1048161 R 546272 CDS YP_002734810.1 225686838 7671570 complement(1049033..1050010) 1 NC_012442.1 peptide ABC transporter ATPase 1050010 7671570 BMEA_B1076 Brucella melitensis ATCC 23457 peptide ABC transporter ATPase YP_002734810.1 1049033 R 546272 CDS YP_002734811.1 225686839 7671571 complement(1050007..1050999) 1 NC_012442.1 ABC transporter 1050999 7671571 BMEA_B1077 Brucella melitensis ATCC 23457 ABC transporter YP_002734811.1 1050007 R 546272 CDS YP_002734812.1 225686840 7671573 complement(1051828..1052838) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 1052838 7671573 BMEA_B1079 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734812.1 1051828 R 546272 CDS YP_002734813.1 225686841 7671574 complement(1052874..1054430) 1 NC_012442.1 glutathione-binding protein GsiB 1054430 7671574 BMEA_B1080 Brucella melitensis ATCC 23457 glutathione-binding protein GsiB YP_002734813.1 1052874 R 546272 CDS YP_002734814.1 225686842 7671575 complement(1054496..1054978) 1 NC_012442.1 GntR family transcriptional regulator 1054978 7671575 BMEA_B1081 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734814.1 1054496 R 546272 CDS YP_002734815.1 225686843 7671576 complement(1055202..1056206) 1 NC_012442.1 ABC transporter 1056206 7671576 BMEA_B1082 Brucella melitensis ATCC 23457 ABC transporter YP_002734815.1 1055202 R 546272 CDS YP_002734816.1 225686844 7671577 complement(1056203..1057201) 1 NC_012442.1 ABC transporter 1057201 7671577 BMEA_B1083 Brucella melitensis ATCC 23457 ABC transporter YP_002734816.1 1056203 R 546272 CDS YP_002734817.1 225686845 7671578 complement(1057204..1058094) 1 NC_012442.1 peptide ABC transporter permease 1058094 7671578 BMEA_B1084 Brucella melitensis ATCC 23457 peptide ABC transporter permease YP_002734817.1 1057204 R 546272 CDS YP_002734818.1 225686846 7671579 complement(1058087..1059031) 1 NC_012442.1 peptide ABC transporter permease 1059031 7671579 BMEA_B1085 Brucella melitensis ATCC 23457 peptide ABC transporter permease YP_002734818.1 1058087 R 546272 CDS YP_002734819.1 225686847 7671580 complement(1059184..1060728) 1 NC_012442.1 extracellular solute-binding protein 1060728 7671580 BMEA_B1086 Brucella melitensis ATCC 23457 extracellular solute-binding protein YP_002734819.1 1059184 R 546272 CDS YP_002734820.1 225686848 7671582 complement(1063361..1064503) 1 NC_012442.1 acyl-CoA dehydrogenase 1064503 7671582 BMEA_B1088 Brucella melitensis ATCC 23457 acyl-CoA dehydrogenase YP_002734820.1 1063361 R 546272 CDS YP_002734821.1 225686849 7671583 1064620..1065468 1 NC_012442.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1065468 7671583 BMEA_B1089 Brucella melitensis ATCC 23457 enoyl-CoA hydratase YP_002734821.1 1064620 D 546272 CDS YP_002734822.1 225686850 7671584 1065470..1066990 1 NC_012442.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxy-acyl-CoA dehydrogenase 1066990 7671584 BMEA_B1090 Brucella melitensis ATCC 23457 3-hydroxy-acyl-CoA dehydrogenase YP_002734822.1 1065470 D 546272 CDS YP_002734823.1 225686851 7671585 1067005..1069182 1 NC_012442.1 2-oxoisovalerate dehydrogenase subunit beta 1069182 7671585 BMEA_B1091 Brucella melitensis ATCC 23457 2-oxoisovalerate dehydrogenase subunit beta YP_002734823.1 1067005 D 546272 CDS YP_002734824.1 225686852 7671586 1069212..1070831 1 NC_012442.1 glutathione-binding protein GsiB 1070831 7671586 BMEA_B1092 Brucella melitensis ATCC 23457 glutathione-binding protein GsiB YP_002734824.1 1069212 D 546272 CDS YP_002734825.1 225686853 7671587 complement(1070915..1072201) 1 NC_012442.1 branched-chain alpha-keto acid dehydrogenase subunit E2 1072201 7671587 BMEA_B1093 Brucella melitensis ATCC 23457 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002734825.1 1070915 R 546272 CDS YP_002734826.1 225686854 7671588 complement(1072261..1073067) 1 NC_012442.1 transcriptional regulator 1073067 7671588 BMEA_B1094 Brucella melitensis ATCC 23457 transcriptional regulator YP_002734826.1 1072261 R 546272 CDS YP_002734827.1 225686855 7671589 1073253..1074266 1 NC_012442.1 dipeptide transport system permease DppB 1074266 7671589 BMEA_B1095 Brucella melitensis ATCC 23457 dipeptide transport system permease DppB YP_002734827.1 1073253 D 546272 CDS YP_002734828.1 225686856 7671590 1074278..1074934 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 1074934 7671590 BMEA_B1096 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734828.1 1074278 D 546272 CDS YP_002734829.1 225686857 7671591 1074947..1075984 1 NC_012442.1 ABC transporter 1075984 7671591 BMEA_B1097 Brucella melitensis ATCC 23457 ABC transporter YP_002734829.1 1074947 D 546272 CDS YP_002734830.1 225686858 7671592 1075977..1076981 1 NC_012442.1 ABC transporter 1076981 7671592 BMEA_B1098 Brucella melitensis ATCC 23457 ABC transporter YP_002734830.1 1075977 D 546272 CDS YP_002734831.1 225686859 7671593 1077037..1078299 1 NC_012442.1 L-carnitine dehydratase/bile acid-inducible protein F 1078299 7671593 BMEA_B1099 Brucella melitensis ATCC 23457 L-carnitine dehydratase/bile acid-inducible protein F YP_002734831.1 1077037 D 546272 CDS YP_002734832.1 225686860 7671595 complement(1079825..1079953) 1 NC_012442.1 hypothetical protein 1079953 7671595 BMEA_B1101 Brucella melitensis ATCC 23457 hypothetical protein YP_002734832.1 1079825 R 546272 CDS YP_002734833.1 225686861 7671596 complement(1079950..1080681) 1 NC_012442.1 transcriptional regulatory protein 1080681 7671596 BMEA_B1102 Brucella melitensis ATCC 23457 transcriptional regulatory protein YP_002734833.1 1079950 R 546272 CDS YP_002734834.1 225686862 7671597 1081201..1082082 1 NC_012442.1 Integrase, catalytic domain-containing protein 1082082 7671597 BMEA_B1103 Brucella melitensis ATCC 23457 Integrase, catalytic domain-containing protein YP_002734834.1 1081201 D 546272 CDS YP_002734835.1 225686863 7671600 1082549..1082701 1 NC_012442.1 hypothetical protein 1082701 7671600 BMEA_B1106 Brucella melitensis ATCC 23457 hypothetical protein YP_002734835.1 1082549 D 546272 CDS YP_002734836.1 225686864 7671602 1085656..1085898 1 NC_012442.1 hypothetical protein 1085898 7671602 BMEA_B1108 Brucella melitensis ATCC 23457 hypothetical protein YP_002734836.1 1085656 D 546272 CDS YP_002734837.1 225686865 7671606 1088574..1089440 1 NC_012442.1 BadF/BadG/BcrA/BcrD type ATPase 1089440 7671606 BMEA_B1112 Brucella melitensis ATCC 23457 BadF/BadG/BcrA/BcrD type ATPase YP_002734837.1 1088574 D 546272 CDS YP_002734838.1 225686866 7671607 1089651..1090151 1 NC_012442.1 Rrf2 family transcriptional regulator 1090151 7671607 BMEA_B1113 Brucella melitensis ATCC 23457 Rrf2 family transcriptional regulator YP_002734838.1 1089651 D 546272 CDS YP_002734839.1 225686867 7671608 complement(1090212..1091414) 1 NC_012442.1 cobalamin synthesis protein/P47K family protein 1091414 7671608 BMEA_B1114 Brucella melitensis ATCC 23457 cobalamin synthesis protein/P47K family protein YP_002734839.1 1090212 R 546272 CDS YP_002734840.1 225686868 7671609 1091439..1091579 1 NC_012442.1 hypothetical protein 1091579 7671609 BMEA_B1115 Brucella melitensis ATCC 23457 hypothetical protein YP_002734840.1 1091439 D 546272 CDS YP_002734841.1 225686869 7671610 complement(1091581..1092585) 1 NC_012442.1 zinc uptake ABC transporter substrate-binding protein 1092585 7671610 BMEA_B1116 Brucella melitensis ATCC 23457 zinc uptake ABC transporter substrate-binding protein YP_002734841.1 1091581 R 546272 CDS YP_002734842.1 225686870 7671611 1092812..1093708 1 NC_012442.1 Zinc import ATP-binding protein znuC 1093708 7671611 BMEA_B1117 Brucella melitensis ATCC 23457 Zinc import ATP-binding protein znuC YP_002734842.1 1092812 D 546272 CDS YP_002734843.1 225686871 7671612 1093662..1094522 1 NC_012442.1 zinc ABC transporter permease 1094522 7671612 BMEA_B1118 Brucella melitensis ATCC 23457 zinc ABC transporter permease YP_002734843.1 1093662 D 546272 CDS YP_002734844.1 225686872 7671613 1094519..1094956 1 NC_012442.1 ferric uptake regulator Fur family protein 1094956 7671613 BMEA_B1119 Brucella melitensis ATCC 23457 ferric uptake regulator Fur family protein YP_002734844.1 1094519 D 546272 CDS YP_002734845.1 225686873 7671614 1095083..1095418 1 NC_012442.1 type IV pilus assembly PilZ 1095418 7671614 BMEA_B1120 Brucella melitensis ATCC 23457 type IV pilus assembly PilZ YP_002734845.1 1095083 D 546272 CDS YP_002734846.1 225686874 7671615 complement(1095406..1095933) 1 NC_012442.1 hypothetical protein 1095933 7671615 BMEA_B1121 Brucella melitensis ATCC 23457 hypothetical protein YP_002734846.1 1095406 R 546272 CDS YP_002734847.1 225686875 7671616 complement(1095930..1096406) 1 NC_012442.1 hypothetical protein 1096406 7671616 BMEA_B1122 Brucella melitensis ATCC 23457 hypothetical protein YP_002734847.1 1095930 R 546272 CDS YP_002734848.1 225686876 7671617 complement(1096533..1097123) 1 NC_012442.1 hypothetical protein 1097123 7671617 BMEA_B1123 Brucella melitensis ATCC 23457 hypothetical protein YP_002734848.1 1096533 R 546272 CDS YP_002734849.1 225686877 7671618 complement(1097191..1097598) 1 NC_012442.1 hypothetical protein 1097598 7671618 BMEA_B1124 Brucella melitensis ATCC 23457 hypothetical protein YP_002734849.1 1097191 R 546272 CDS YP_002734850.1 225686878 7671619 complement(1097606..1098373) 1 NC_012442.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1098373 fliR 7671619 fliR Brucella melitensis ATCC 23457 flagellar biosynthesis protein FliR YP_002734850.1 1097606 R 546272 CDS YP_002734851.1 225686879 7671621 complement(1100640..1100906) 1 NC_012442.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ 1100906 fliQ 7671621 fliQ Brucella melitensis ATCC 23457 flagellar biosynthesis protein FliQ YP_002734851.1 1100640 R 546272 CDS YP_002734852.1 225686880 7671622 complement(1100918..1101331) 1 NC_012442.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein 1101331 flgD 7671622 flgD Brucella melitensis ATCC 23457 flagellar basal body rod modification protein YP_002734852.1 1100918 R 546272 CDS YP_002734853.1 225686881 7671623 complement(1101328..1101786) 1 NC_012442.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT 1101786 flbT 7671623 flbT Brucella melitensis ATCC 23457 flagellar biosynthesis repressor FlbT YP_002734853.1 1101328 R 546272 CDS YP_002734854.1 225686882 7671624 complement(1101788..1102132) 1 NC_012442.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF 1102132 flaF 7671624 flaF Brucella melitensis ATCC 23457 flagellar biosynthesis regulatory protein FlaF YP_002734854.1 1101788 R 546272 CDS YP_002734855.1 225686883 7671625 complement(1102264..1103310) 1 NC_012442.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL 1103310 flgL 7671625 flgL Brucella melitensis ATCC 23457 flagellar hook-associated protein FlgL YP_002734855.1 1102264 R 546272 CDS YP_002734856.1 225686884 7671626 complement(1103316..1104770) 1 NC_012442.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1104770 flgK 7671626 flgK Brucella melitensis ATCC 23457 flagellar hook-associated protein FlgK YP_002734856.1 1103316 R 546272 CDS YP_002734857.1 225686885 7671627 complement(1104895..1106085) 1 NC_012442.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1106085 flgE 7671627 flgE Brucella melitensis ATCC 23457 flagellar hook protein FlgE YP_002734857.1 1104895 R 546272 CDS YP_002734858.1 225686886 7671628 complement(1106496..1107179) 1 NC_012442.1 protein petR 1107179 7671628 BMEA_B1134 Brucella melitensis ATCC 23457 protein petR YP_002734858.1 1106496 R 546272 CDS YP_002734859.1 225686887 7671629 complement(1107507..1108079) 1 NC_012442.1 Lytic transglycosylase catalytic 1108079 7671629 BMEA_B1135 Brucella melitensis ATCC 23457 Lytic transglycosylase catalytic YP_002734859.1 1107507 R 546272 CDS YP_002734860.1 225686888 7671630 complement(1108033..1109307) 1 NC_012442.1 flagellar hook-length control protein 1109307 7671630 BMEA_B1136 Brucella melitensis ATCC 23457 flagellar hook-length control protein YP_002734860.1 1108033 R 546272 CDS YP_002734861.1 225686889 7671631 complement(1109304..1110596) 1 NC_012442.1 a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation; chemotaxis protein 1110596 7671631 BMEA_B1137 Brucella melitensis ATCC 23457 chemotaxis protein YP_002734861.1 1109304 R 546272 CDS YP_002734862.1 225686890 7671632 complement(1110593..1111693) 1 NC_012442.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1111693 motB 7671632 motB Brucella melitensis ATCC 23457 flagellar motor protein MotB YP_002734862.1 1110593 R 546272 CDS YP_002734863.1 225686891 7671633 complement(1111690..1112370) 1 NC_012442.1 hypothetical protein 1112370 7671633 BMEA_B1139 Brucella melitensis ATCC 23457 hypothetical protein YP_002734863.1 1111690 R 546272 CDS YP_002734864.1 225686892 7671635 complement(1114318..1115166) 1 NC_012442.1 Flagellin A 1115166 7671635 BMEA_B1141 Brucella melitensis ATCC 23457 Flagellin A YP_002734864.1 1114318 R 546272 CDS YP_002734865.1 225686893 7671637 complement(1126187..1127242) 1 NC_012442.1 hypothetical protein 1127242 7671637 BMEA_B1143 Brucella melitensis ATCC 23457 hypothetical protein YP_002734865.1 1126187 R 546272 CDS YP_002734866.1 225686894 7671638 1127816..1128835 1 NC_012442.1 D-xylose ABC transporter substrate-binding protein 1128835 xylF 7671638 xylF Brucella melitensis ATCC 23457 D-xylose ABC transporter substrate-binding protein YP_002734866.1 1127816 D 546272 CDS YP_002734867.1 225686895 7671639 1128997..1130532 1 NC_012442.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 1130532 xylG 7671639 xylG Brucella melitensis ATCC 23457 xylose transporter ATP-binding subunit YP_002734867.1 1128997 D 546272 CDS YP_002734868.1 225686896 7671640 1130675..1131844 1 NC_012442.1 monosaccharide-transporting ATPase 1131844 7671640 BMEA_B1146 Brucella melitensis ATCC 23457 monosaccharide-transporting ATPase YP_002734868.1 1130675 D 546272 CDS YP_002734869.1 225686897 7671641 1131888..1132091 1 NC_012442.1 hypothetical protein 1132091 7671641 BMEA_B1147 Brucella melitensis ATCC 23457 hypothetical protein YP_002734869.1 1131888 D 546272 CDS YP_002734870.1 225686898 7671642 1132402..1133370 1 NC_012442.1 AraC family transcriptional regulator 1133370 7671642 BMEA_B1148 Brucella melitensis ATCC 23457 AraC family transcriptional regulator YP_002734870.1 1132402 D 546272 CDS YP_002734871.1 225686899 7671644 1134876..1135013 1 NC_012442.1 hypothetical protein 1135013 7671644 BMEA_B1150 Brucella melitensis ATCC 23457 hypothetical protein YP_002734871.1 1134876 D 546272 CDS YP_002734872.1 225686900 7671645 complement(1135033..1135842) 1 NC_012442.1 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 1135842 hpaI 7671645 hpaI Brucella melitensis ATCC 23457 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_002734872.1 1135033 R 546272 CDS YP_002734873.1 225686901 7671646 complement(1136060..1136863) 1 NC_012442.1 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1136863 hpaH 7671646 hpaH Brucella melitensis ATCC 23457 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_002734873.1 1136060 R 546272 CDS YP_002734874.1 225686902 7671647 complement(1136867..1137733) 1 NC_012442.1 Fumarylacetoacetate hydrolase domain-containing protein 2 1137733 7671647 BMEA_B1154 Brucella melitensis ATCC 23457 Fumarylacetoacetate hydrolase domain-containing protein 2 YP_002734874.1 1136867 R 546272 CDS YP_002734875.1 225686903 7671648 complement(1137802..1138782) 1 NC_012442.1 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1138782 hpaD 7671648 hpaD Brucella melitensis ATCC 23457 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_002734875.1 1137802 R 546272 CDS YP_002734876.1 225686904 7671649 complement(1138837..1140351) 1 NC_012442.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 1140351 hpaE 7671649 hpaE Brucella melitensis ATCC 23457 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_002734876.1 1138837 R 546272 CDS YP_002734877.1 225686905 7671650 complement(1140421..1140813) 1 NC_012442.1 5-carboxymethyl-2-hydroxymuconate Delta-isomerase 1140813 7671650 BMEA_B1157 Brucella melitensis ATCC 23457 5-carboxymethyl-2-hydroxymuconate Delta-isomerase YP_002734877.1 1140421 R 546272 CDS YP_002734878.1 225686906 7671651 1140979..1141470 1 NC_012442.1 homoprotocatechuate degradation operon regulator HpaR 1141470 hpaR 7671651 hpaR Brucella melitensis ATCC 23457 homoprotocatechuate degradation operon regulator HpaR YP_002734878.1 1140979 D 546272 CDS YP_002734879.1 225686907 7671652 complement(1141460..1142452) 1 NC_012442.1 Homoserine kinase 1142452 7671652 BMEA_B1159 Brucella melitensis ATCC 23457 Homoserine kinase YP_002734879.1 1141460 R 546272 CDS YP_002734880.1 225686908 7671653 complement(1142457..1143740) 1 NC_012442.1 aminotransferase class-III protein 1143740 7671653 BMEA_B1160 Brucella melitensis ATCC 23457 aminotransferase class-III protein YP_002734880.1 1142457 R 546272 CDS YP_002734881.1 225686909 7671654 complement(1143742..1145100) 1 NC_012442.1 hypothetical protein 1145100 7671654 BMEA_B1161 Brucella melitensis ATCC 23457 hypothetical protein YP_002734881.1 1143742 R 546272 CDS YP_002734882.1 225686910 7671655 complement(1145113..1145757) 1 NC_012442.1 HAD-superfamily hydrolase 1145757 7671655 BMEA_B1162 Brucella melitensis ATCC 23457 HAD-superfamily hydrolase YP_002734882.1 1145113 R 546272 CDS YP_002734883.1 225686911 7671656 complement(1145754..1147010) 1 NC_012442.1 hypothetical protein 1147010 7671656 BMEA_B1163 Brucella melitensis ATCC 23457 hypothetical protein YP_002734883.1 1145754 R 546272 CDS YP_002734884.1 225686912 7671657 complement(1147010..1147792) 1 NC_012442.1 HTH-type transcriptional repressor AllR 1147792 7671657 BMEA_B1164 Brucella melitensis ATCC 23457 HTH-type transcriptional repressor AllR YP_002734884.1 1147010 R 546272 CDS YP_002734885.1 225686913 7671658 1148042..1149535 1 NC_012442.1 amino acid permease-associated protein 1149535 7671658 BMEA_B1165 Brucella melitensis ATCC 23457 amino acid permease-associated protein YP_002734885.1 1148042 D 546272 CDS YP_002734886.1 225686914 7671659 1149607..1151085 1 NC_012442.1 aldehyde dehydrogenase 1151085 7671659 BMEA_B1166 Brucella melitensis ATCC 23457 aldehyde dehydrogenase YP_002734886.1 1149607 D 546272 CDS YP_002734887.1 225686915 7671660 1151244..1152926 1 NC_012442.1 exoenzymes regulatory protein AepA 1152926 7671660 BMEA_B1167 Brucella melitensis ATCC 23457 exoenzymes regulatory protein AepA YP_002734887.1 1151244 D 546272 CDS YP_002734888.1 225686916 7671661 1152993..1154174 1 NC_012442.1 hypothetical protein 1154174 7671661 BMEA_B1168 Brucella melitensis ATCC 23457 hypothetical protein YP_002734888.1 1152993 D 546272 CDS YP_002734889.1 225686917 7671662 1154247..1155116 1 NC_012442.1 hypothetical protein 1155116 7671662 BMEA_B1169 Brucella melitensis ATCC 23457 hypothetical protein YP_002734889.1 1154247 D 546272 CDS YP_002734890.1 225686918 7671664 1156812..1157516 1 NC_012442.1 branched-chain amino acid transport ATP-binding protein livF 1157516 7671664 BMEA_B1171 Brucella melitensis ATCC 23457 branched-chain amino acid transport ATP-binding protein livF YP_002734890.1 1156812 D 546272 CDS YP_002734891.1 225686919 7671665 complement(1157611..1157934) 1 NC_012442.1 hypothetical protein 1157934 7671665 BMEA_B1172 Brucella melitensis ATCC 23457 hypothetical protein YP_002734891.1 1157611 R 546272 CDS YP_002734892.1 225686920 7671667 complement(1158824..1159558) 1 NC_012442.1 GntR family transcriptional regulator 1159558 7671667 BMEA_B1174 Brucella melitensis ATCC 23457 GntR family transcriptional regulator YP_002734892.1 1158824 R 546272 CDS YP_002734893.1 225686921 7671668 complement(1159703..1160968) 1 NC_012442.1 sn-glycerol-3-phosphate-binding periplasmic protein UgpB 1160968 7671668 BMEA_B1175 Brucella melitensis ATCC 23457 sn-glycerol-3-phosphate-binding periplasmic protein UgpB YP_002734893.1 1159703 R 546272 CDS YP_002734894.1 225686922 7671669 complement(1161003..1161824) 1 NC_012442.1 hypothetical protein 1161824 7671669 BMEA_B1176 Brucella melitensis ATCC 23457 hypothetical protein YP_002734894.1 1161003 R 546272 CDS YP_002734895.1 225686923 7671670 complement(1161835..1162794) 1 NC_012442.1 hypothetical protein 1162794 7671670 BMEA_B1177 Brucella melitensis ATCC 23457 hypothetical protein YP_002734895.1 1161835 R 546272 CDS YP_002734896.1 225686924 7671671 complement(1162760..1163932) 1 NC_012442.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC 1163932 7671671 BMEA_B1178 Brucella melitensis ATCC 23457 sn-glycerol-3-phosphate import ATP-binding protein UgpC YP_002734896.1 1162760 R 546272 CDS YP_002734897.1 225686925 7671672 complement(1163929..1164774) 1 NC_012442.1 metallophosphoesterase 1164774 7671672 BMEA_B1179 Brucella melitensis ATCC 23457 metallophosphoesterase YP_002734897.1 1163929 R 546272 CDS YP_002734898.1 225686926 7671673 complement(1165049..1166536) 1 NC_012442.1 arylsulfatase D 1166536 7671673 BMEA_B1180 Brucella melitensis ATCC 23457 arylsulfatase D YP_002734898.1 1165049 R 546272 CDS YP_002734899.1 225686927 7671674 complement(1166679..1167638) 1 NC_012442.1 aliphatic sulfonate ABC transporter substrate-binding protein 1167638 7671674 BMEA_B1181 Brucella melitensis ATCC 23457 aliphatic sulfonate ABC transporter substrate-binding protein YP_002734899.1 1166679 R 546272 CDS YP_002734900.1 225686928 7671675 complement(1167654..1168367) 1 NC_012442.1 ABC transporter 1168367 7671675 BMEA_B1182 Brucella melitensis ATCC 23457 ABC transporter YP_002734900.1 1167654 R 546272 CDS YP_002734901.1 225686929 7671676 complement(1168376..1169116) 1 NC_012442.1 binding-protein-dependent transport systems inner membrane component 1169116 7671676 BMEA_B1183 Brucella melitensis ATCC 23457 binding-protein-dependent transport systems inner membrane component YP_002734901.1 1168376 R 546272 CDS YP_002734902.1 225686930 7671677 complement(1169113..1170237) 1 NC_012442.1 ROK family protein 1170237 7671677 BMEA_B1184 Brucella melitensis ATCC 23457 ROK family protein YP_002734902.1 1169113 R 546272 CDS YP_002734903.1 225686931 7671678 complement(1170493..1172478) 1 NC_012442.1 Heme transporter bhuA 1172478 7671678 BMEA_B1185 Brucella melitensis ATCC 23457 Heme transporter bhuA YP_002734903.1 1170493 R 546272 CDS YP_002734904.1 225686932 7671679 1172921..1173724 1 NC_012442.1 hypothetical protein 1173724 7671679 BMEA_B1186 Brucella melitensis ATCC 23457 hypothetical protein YP_002734904.1 1172921 D 546272 CDS YP_002734905.1 225686933 7671680 1173703..1173882 1 NC_012442.1 hypothetical protein 1173882 7671680 BMEA_B1187 Brucella melitensis ATCC 23457 hypothetical protein YP_002734905.1 1173703 D 546272 CDS YP_002734906.1 225686934 7671681 1173889..1175094 1 NC_012442.1 extracellular ligand-binding receptor 1175094 7671681 BMEA_B1188 Brucella melitensis ATCC 23457 extracellular ligand-binding receptor YP_002734906.1 1173889 D 546272 CDS YP_002734907.1 225686935 7671682 1175296..1176159 1 NC_012442.1 high-affinity branched-chain amino acid transporter membrane protein 1176159 7671682 BMEA_B1189 Brucella melitensis ATCC 23457 high-affinity branched-chain amino acid transporter membrane protein YP_002734907.1 1175296 D 546272 CDS YP_002734908.1 225686936 7671683 1176156..1177103 1 NC_012442.1 high-affinity branched-chain amino acid transporter membrane protein 1177103 7671683 BMEA_B1190 Brucella melitensis ATCC 23457 high-affinity branched-chain amino acid transporter membrane protein YP_002734908.1 1176156 D 546272 CDS YP_002734909.1 225686937 7671685 1177829..1178557 1 NC_012442.1 high-affinity branched-chain amino acid transporter ATP-binding protein 1178557 7671685 BMEA_B1192 Brucella melitensis ATCC 23457 high-affinity branched-chain amino acid transporter ATP-binding protein YP_002734909.1 1177829 D 546272 CDS YP_002734910.1 225686938 7671686 complement(1178586..1180526) 1 NC_012442.1 heavy metal translocating P-type ATPase 1180526 7671686 BMEA_B1193 Brucella melitensis ATCC 23457 heavy metal translocating P-type ATPase YP_002734910.1 1178586 R 546272 CDS YP_002734911.1 225686939 7671687 complement(1180806..1182158) 1 NC_012442.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1182158 hemN 7671687 hemN Brucella melitensis ATCC 23457 coproporphyrinogen III oxidase YP_002734911.1 1180806 R 546272 CDS YP_002734912.1 225686940 7671688 complement(1182251..1182475) 1 NC_012442.1 hypothetical protein 1182475 7671688 BMEA_B1195 Brucella melitensis ATCC 23457 hypothetical protein YP_002734912.1 1182251 R 546272 CDS YP_002734913.1 225686941 7671689 complement(1182442..1182846) 1 NC_012442.1 hypothetical protein 1182846 7671689 BMEA_B1196 Brucella melitensis ATCC 23457 hypothetical protein YP_002734913.1 1182442 R 546272 CDS YP_002734914.1 225686942 7671690 1183060..1184253 1 NC_012442.1 plasmid partitioning protein RepA 1184253 repA 7671690 repA Brucella melitensis ATCC 23457 plasmid partitioning protein RepA YP_002734914.1 1183060 D 546272 CDS YP_002734915.1 225686943 7671691 1184318..1185304 1 NC_012442.1 plasmid partitioning protein RepB 1185304 repB 7671691 repB Brucella melitensis ATCC 23457 plasmid partitioning protein RepB YP_002734915.1 1184318 D 546272 CDS