-- dump date 20140619_010922 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 546272000001 SEQ_END SEQ_END NC_012441.1 2125701 2125701 DR NC_012441.1; contig end 2125701..2125701 Brucella melitensis ATCC 23457 546272000002 SEQ_END SEQ_END NC_012442.1 1185518 1185518 DR NC_012442.1; contig end 1185518..1185518 Brucella melitensis ATCC 23457 YP_002731780.1 CDS dnaA NC_012441.1 634 2274 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 634..2274 Brucella melitensis ATCC 23457 7676729 YP_002731781.1 CDS dnaN NC_012441.1 2503 3696 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2503..3696 Brucella melitensis ATCC 23457 7678227 YP_002731782.1 CDS recF NC_012441.1 3878 5032 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3878..5032 Brucella melitensis ATCC 23457 7678228 YP_002731783.1 CDS BMEA_A0004 NC_012441.1 5070 5852 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 5070..5852 Brucella melitensis ATCC 23457 7678229 YP_002731784.1 CDS BMEA_A0005 NC_012441.1 5869 6825 R D-isomer specific 2-hydroxyacid dehydrogenase complement(5869..6825) Brucella melitensis ATCC 23457 7678230 YP_002731785.1 CDS BMEA_A0006 NC_012441.1 6822 8447 R ABC transporter complement(6822..8447) Brucella melitensis ATCC 23457 7678231 YP_002731786.1 CDS BMEA_A0007 NC_012441.1 8471 9610 R binding-protein-dependent transport systems inner membrane protein complement(8471..9610) Brucella melitensis ATCC 23457 7678232 YP_002731787.1 CDS BMEA_A0008 NC_012441.1 9610 10707 R hypothetical protein complement(9610..10707) Brucella melitensis ATCC 23457 7678233 YP_002731788.1 CDS BMEA_A0009 NC_012441.1 10819 12657 R family 5 extracellular solute-binding protein complement(10819..12657) Brucella melitensis ATCC 23457 7678234 YP_002731789.1 CDS BMEA_A0010 NC_012441.1 12671 14539 R family 5 extracellular solute-binding protein complement(12671..14539) Brucella melitensis ATCC 23457 7678235 YP_002731790.1 CDS BMEA_A0011 NC_012441.1 14770 15093 R hypothetical protein complement(14770..15093) Brucella melitensis ATCC 23457 7678236 YP_002731791.1 CDS BMEA_A0012 NC_012441.1 15139 15339 R hypothetical protein complement(15139..15339) Brucella melitensis ATCC 23457 7678237 YP_002731792.1 CDS BMEA_A0013 NC_012441.1 15379 15537 R hypothetical protein complement(15379..15537) Brucella melitensis ATCC 23457 7678238 YP_002731793.1 CDS BMEA_A0014 NC_012441.1 15994 17100 R extracellular ligand-binding receptor complement(15994..17100) Brucella melitensis ATCC 23457 7678239 YP_002731794.1 CDS BMEA_A0016 NC_012441.1 17372 17572 D hypothetical protein 17372..17572 Brucella melitensis ATCC 23457 7678241 YP_002731795.1 CDS BMEA_A0017 NC_012441.1 18358 19221 R catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; hydroxymethylglutaryl-CoA lyase complement(18358..19221) Brucella melitensis ATCC 23457 7678242 YP_002731796.1 CDS BMEA_A0018 NC_012441.1 19214 21181 R carbamoyl-phosphate synthase subunit L complement(19214..21181) Brucella melitensis ATCC 23457 7678243 YP_002731797.1 CDS BMEA_A0019 NC_012441.1 21247 22854 R propionyl-CoA carboxylase complement(21247..22854) Brucella melitensis ATCC 23457 7678244 YP_002731798.1 CDS BMEA_A0020 NC_012441.1 22854 24032 R isovaleryl-CoA dehydrogenase complement(22854..24032) Brucella melitensis ATCC 23457 7678245 YP_002731799.1 CDS BMEA_A0022 NC_012441.1 26352 26786 R CHRD domain-containing protein complement(26352..26786) Brucella melitensis ATCC 23457 7678247 YP_002731800.1 CDS BMEA_A0023 NC_012441.1 26963 28084 R acyltransferase MdmB complement(26963..28084) Brucella melitensis ATCC 23457 7678248 YP_002731801.1 CDS BMEA_A0025 NC_012441.1 28607 28990 R hypothetical protein complement(28607..28990) Brucella melitensis ATCC 23457 7678250 YP_002731802.1 CDS aroA NC_012441.1 29375 30727 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 29375..30727 Brucella melitensis ATCC 23457 7678251 YP_002731803.1 CDS cmk NC_012441.1 30724 31383 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 30724..31383 Brucella melitensis ATCC 23457 7678252 YP_002731804.1 CDS rpsA NC_012441.1 31599 33299 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 31599..33299 Brucella melitensis ATCC 23457 7678253 YP_002731805.1 CDS BMEA_A0029 NC_012441.1 33717 34727 R hypothetical protein complement(33717..34727) Brucella melitensis ATCC 23457 7678254 YP_002731806.1 CDS BMEA_A0030 NC_012441.1 34843 35742 D LysR family transcriptional regulator 34843..35742 Brucella melitensis ATCC 23457 7678255 YP_002731807.1 CDS BMEA_A0031 NC_012441.1 36348 37631 R lytic murein transglycosylase complement(36348..37631) Brucella melitensis ATCC 23457 7678256 YP_002731808.1 CDS recR NC_012441.1 37647 38252 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(37647..38252) Brucella melitensis ATCC 23457 7678257 YP_002731809.1 CDS BMEA_A0033 NC_012441.1 38383 38706 R hypothetical protein complement(38383..38706) Brucella melitensis ATCC 23457 7678258 YP_002731810.1 CDS dnaX NC_012441.1 38731 40539 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(38731..40539) Brucella melitensis ATCC 23457 7678259 YP_002731811.1 CDS BMEA_A0037 NC_012441.1 40821 41225 D histidine triad protein 40821..41225 Brucella melitensis ATCC 23457 7678261 YP_002731812.1 CDS BMEA_A0038 NC_012441.1 41254 42201 D peroxisomal NADH pyrophosphatase NUDT12 41254..42201 Brucella melitensis ATCC 23457 7678262 YP_002731813.1 CDS BMEA_A0039 NC_012441.1 42202 43065 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(42202..43065) Brucella melitensis ATCC 23457 7678263 YP_002731814.1 CDS kdsB NC_012441.1 43154 43909 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(43154..43909) Brucella melitensis ATCC 23457 7678264 YP_002731815.1 CDS BMEA_A0041 NC_012441.1 44287 44895 D cytochrome c 44287..44895 Brucella melitensis ATCC 23457 7678265 YP_002731816.1 CDS BMEA_A0042 NC_012441.1 44940 45905 R hypothetical protein complement(44940..45905) Brucella melitensis ATCC 23457 7678266 YP_002731817.1 CDS BMEA_A0043 NC_012441.1 45961 46269 D hypothetical protein 45961..46269 Brucella melitensis ATCC 23457 7678267 YP_002731818.1 CDS cyoA NC_012441.1 46444 47472 D ubiquinol oxidase subunit II 46444..47472 Brucella melitensis ATCC 23457 7678268 YP_002731819.1 CDS cyoB NC_012441.1 47536 49515 D cytochrome o ubiquinol oxidase subunit I 47536..49515 Brucella melitensis ATCC 23457 7678269 YP_002731820.1 CDS cyoC NC_012441.1 49519 50148 D cytochrome o ubiquinol oxidase subunit III 49519..50148 Brucella melitensis ATCC 23457 7678270 YP_002731821.1 CDS cyoD NC_012441.1 50148 50513 D cytochrome o ubiquinol oxidase subunit IV 50148..50513 Brucella melitensis ATCC 23457 7678271 YP_002731822.1 CDS BMEA_A0048 NC_012441.1 51067 51663 D SH3 type 3 domain-containing protein 51067..51663 Brucella melitensis ATCC 23457 7678272 YP_002731823.1 CDS BMEA_A0049 NC_012441.1 52148 54067 D surface antigen D15 52148..54067 Brucella melitensis ATCC 23457 7678273 YP_002731824.1 CDS BMEA_A0050 NC_012441.1 54064 58803 D hypothetical protein 54064..58803 Brucella melitensis ATCC 23457 7678274 YP_002731825.1 CDS BMEA_A0052 NC_012441.1 59725 59940 R hypothetical protein complement(59725..59940) Brucella melitensis ATCC 23457 7678276 YP_002731826.1 CDS BMEA_A0053 NC_012441.1 60010 60519 R hypothetical protein complement(60010..60519) Brucella melitensis ATCC 23457 7678277 YP_002731827.1 CDS BMEA_A0054 NC_012441.1 60850 61056 R hypothetical protein complement(60850..61056) Brucella melitensis ATCC 23457 7678278 YP_002731828.1 CDS BMEA_A0055 NC_012441.1 61067 62071 R hypothetical protein complement(61067..62071) Brucella melitensis ATCC 23457 7678279 YP_002731829.1 CDS BMEA_A0056 NC_012441.1 62206 62604 R hypothetical protein complement(62206..62604) Brucella melitensis ATCC 23457 7678280 YP_002731830.1 CDS BMEA_A0057 NC_012441.1 62849 63244 R glyoxalase/bleomycin resistance protein/dioxygenase complement(62849..63244) Brucella melitensis ATCC 23457 7678281 YP_002731831.1 CDS BMEA_A0058 NC_012441.1 63441 64604 D hypothetical protein 63441..64604 Brucella melitensis ATCC 23457 7678282 YP_002731832.1 CDS BMEA_A0059 NC_012441.1 64817 66448 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(64817..66448) Brucella melitensis ATCC 23457 7678283 YP_002731833.1 CDS BMEA_A0061 NC_012441.1 66504 66689 R hypothetical protein complement(66504..66689) Brucella melitensis ATCC 23457 7678284 YP_002731834.1 CDS BMEA_A0062 NC_012441.1 66664 67557 R LysR family transcriptional regulator complement(66664..67557) Brucella melitensis ATCC 23457 7678285 YP_002731835.1 CDS BMEA_A0063 NC_012441.1 67597 67701 R hypothetical protein complement(67597..67701) Brucella melitensis ATCC 23457 7678286 YP_002731836.1 CDS BMEA_A0064 NC_012441.1 67682 68605 D dienelactone hydrolase domain-containing protein 67682..68605 Brucella melitensis ATCC 23457 7678287 YP_002731837.1 CDS BMEA_A0065 NC_012441.1 68678 69376 D putative fructose transport system kinase 68678..69376 Brucella melitensis ATCC 23457 7678288 YP_002731838.1 CDS BMEA_A0066 NC_012441.1 69476 70165 D fumarylacetoacetate hydrolase domain-containing protein 1 69476..70165 Brucella melitensis ATCC 23457 7678289 YP_002731839.1 CDS BMEA_A0067 NC_012441.1 70185 70376 D hypothetical protein 70185..70376 Brucella melitensis ATCC 23457 7678290 YP_002731840.1 CDS BMEA_A0068 NC_012441.1 70438 70653 D hypothetical protein 70438..70653 Brucella melitensis ATCC 23457 7678291 YP_002731841.1 CDS BMEA_A0069 NC_012441.1 70819 71007 D hypothetical protein 70819..71007 Brucella melitensis ATCC 23457 7678292 YP_002731842.1 CDS BMEA_A0070 NC_012441.1 71022 71885 D lytic transglycosylase 71022..71885 Brucella melitensis ATCC 23457 7678293 YP_002731843.1 CDS BMEA_A0071 NC_012441.1 72067 72723 D hemolysin-3 72067..72723 Brucella melitensis ATCC 23457 7678294 YP_002731844.1 CDS dnaE NC_012441.1 72864 76097 R DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase complement(72864..76097) Brucella melitensis ATCC 23457 7678295 YP_002731845.1 CDS BMEA_A0073 NC_012441.1 76097 77683 R hypothetical protein complement(76097..77683) Brucella melitensis ATCC 23457 7678296 YP_002731846.1 CDS BMEA_A0074 NC_012441.1 77574 78437 R hypothetical protein complement(77574..78437) Brucella melitensis ATCC 23457 7678297 YP_002731847.1 CDS BMEA_A0076 NC_012441.1 81199 81936 D hypothetical protein 81199..81936 Brucella melitensis ATCC 23457 7678299 YP_002731848.1 CDS argG NC_012441.1 82015 83235 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(82015..83235) Brucella melitensis ATCC 23457 7678300 YP_002731849.1 CDS BMEA_A0078 NC_012441.1 83422 84081 D hypothetical protein 83422..84081 Brucella melitensis ATCC 23457 7678301 YP_002731850.1 CDS BMEA_A0079 NC_012441.1 84085 84588 R hypothetical protein complement(84085..84588) Brucella melitensis ATCC 23457 7678302 YP_002731851.1 CDS BMEA_A0080 NC_012441.1 84622 85857 R radical SAM protein complement(84622..85857) Brucella melitensis ATCC 23457 7678303 YP_002731852.1 CDS BMEA_A0083 NC_012441.1 86117 86620 R hypothetical protein complement(86117..86620) Brucella melitensis ATCC 23457 7678304 YP_002731853.1 CDS BMEA_A0084 NC_012441.1 87036 87419 R hypothetical protein complement(87036..87419) Brucella melitensis ATCC 23457 7678305 YP_002731854.1 CDS BMEA_A0085 NC_012441.1 87507 87800 R 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase complement(87507..87800) Brucella melitensis ATCC 23457 7678306 YP_002731855.1 CDS BMEA_A0087 NC_012441.1 88542 89132 R 2'-5' RNA ligase complement(88542..89132) Brucella melitensis ATCC 23457 7678307 YP_002731856.1 CDS BMEA_A0088 NC_012441.1 89313 90038 R arylesterase precursor complement(89313..90038) Brucella melitensis ATCC 23457 7676515 YP_002731857.1 CDS BMEA_A0089 NC_012441.1 90035 90613 R hypothetical protein complement(90035..90613) Brucella melitensis ATCC 23457 7676516 YP_002731858.1 CDS BMEA_A0090 NC_012441.1 90784 90912 D ABC transporter 90784..90912 Brucella melitensis ATCC 23457 7676517 YP_002731859.1 CDS BMEA_A0091 NC_012441.1 90909 93458 D hypothetical protein 90909..93458 Brucella melitensis ATCC 23457 7676518 YP_002731860.1 CDS BMEA_A0093 NC_012441.1 93692 94429 D hypothetical protein 93692..94429 Brucella melitensis ATCC 23457 7676519 YP_002731861.1 CDS BMEA_A0094 NC_012441.1 94544 95083 D phosphinothricin N-acetyltransferase 94544..95083 Brucella melitensis ATCC 23457 7676520 YP_002731862.1 CDS BMEA_A0095 NC_012441.1 95103 95504 R hypothetical protein complement(95103..95504) Brucella melitensis ATCC 23457 7676521 YP_002731863.1 CDS BMEA_A0096 NC_012441.1 96054 96788 R hypothetical protein complement(96054..96788) Brucella melitensis ATCC 23457 7676522 YP_002731864.1 CDS BMEA_A0097 NC_012441.1 96941 97081 R hypothetical protein complement(96941..97081) Brucella melitensis ATCC 23457 7676523 YP_002731865.1 CDS acnA NC_012441.1 97065 99752 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(97065..99752) Brucella melitensis ATCC 23457 7676524 YP_002731866.1 CDS ccmA NC_012441.1 100096 100743 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 100096..100743 Brucella melitensis ATCC 23457 7676525 YP_002731867.1 CDS ccmB NC_012441.1 100743 101408 D heme exporter protein CcmB 100743..101408 Brucella melitensis ATCC 23457 7676526 YP_002731868.1 CDS ccmC NC_012441.1 101466 102251 D heme exporter protein CcmC 101466..102251 Brucella melitensis ATCC 23457 7676527 YP_002731869.1 CDS ccmD NC_012441.1 102248 102421 D heme exporter protein CcmD 102248..102421 Brucella melitensis ATCC 23457 7676528 YP_002731870.1 CDS dsbE NC_012441.1 102418 103029 D periplasmic protein thiol:disulfide oxidoreductase 102418..103029 Brucella melitensis ATCC 23457 7676529 YP_002731871.1 CDS ilvD NC_012441.1 103278 105113 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(103278..105113) Brucella melitensis ATCC 23457 7676530 YP_002731872.1 CDS BMEA_A0106 NC_012441.1 105286 105423 D hypothetical protein 105286..105423 Brucella melitensis ATCC 23457 7676531 YP_002731873.1 CDS BMEA_A0107 NC_012441.1 105504 105935 R hypothetical protein complement(105504..105935) Brucella melitensis ATCC 23457 7676532 YP_002731874.1 CDS BMEA_A0108 NC_012441.1 105962 106339 R response regulator receiver protein complement(105962..106339) Brucella melitensis ATCC 23457 7676533 YP_002731875.1 CDS BMEA_A0109 NC_012441.1 106514 106750 R AsnC family transcriptional regulator complement(106514..106750) Brucella melitensis ATCC 23457 7676534 YP_002731876.1 CDS BMEA_A0110 NC_012441.1 107069 107257 D hypothetical protein 107069..107257 Brucella melitensis ATCC 23457 7676535 YP_002731877.1 CDS BMEA_A0111 NC_012441.1 107403 107807 D hypothetical protein 107403..107807 Brucella melitensis ATCC 23457 7676536 YP_002731878.1 CDS BMEA_A0112 NC_012441.1 107893 108597 R hypothetical protein complement(107893..108597) Brucella melitensis ATCC 23457 7676537 YP_002731879.1 CDS BMEA_A0113 NC_012441.1 108669 109487 D hypothetical protein 108669..109487 Brucella melitensis ATCC 23457 7676538 YP_002731880.1 CDS BMEA_A0114 NC_012441.1 109765 110793 D sulfate ABC transporter substrate-binding protein 109765..110793 Brucella melitensis ATCC 23457 7676539 YP_002731881.1 CDS cysT NC_012441.1 110888 111754 D sulfate ABC transporter permease CysT 110888..111754 Brucella melitensis ATCC 23457 7676540 YP_002731882.1 CDS cysW NC_012441.1 111744 112610 D sulfate ABC transporter permease CysW 111744..112610 Brucella melitensis ATCC 23457 7676541 YP_002731883.1 CDS cysA NC_012441.1 112708 113787 D sulfate ABC transporter ATP-binding protein 112708..113787 Brucella melitensis ATCC 23457 7676542 YP_002731884.1 CDS BMEA_A0118 NC_012441.1 114173 122776 D glycosyltransferase 114173..122776 Brucella melitensis ATCC 23457 7676543 YP_002731885.1 CDS pncB NC_012441.1 122866 124170 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 122866..124170 Brucella melitensis ATCC 23457 7676544 YP_002731886.1 CDS BMEA_A0120 NC_012441.1 124212 125042 R phenazine biosynthesis protein PhzF family protein complement(124212..125042) Brucella melitensis ATCC 23457 7676545 YP_002731887.1 CDS BMEA_A0121 NC_012441.1 125152 125940 R methyltransferase type 11 complement(125152..125940) Brucella melitensis ATCC 23457 7676546 YP_002731888.1 CDS BMEA_A0122 NC_012441.1 125963 126898 R fructokinase complement(125963..126898) Brucella melitensis ATCC 23457 7676547 YP_002731889.1 CDS BMEA_A0123 NC_012441.1 126989 127795 R short-chain dehydrogenase/reductase SDR complement(126989..127795) Brucella melitensis ATCC 23457 7676548 YP_002731890.1 CDS BMEA_A0124 NC_012441.1 127916 130207 R 1A family penicillin-binding protein complement(127916..130207) Brucella melitensis ATCC 23457 7676549 YP_002731891.1 CDS BMEA_A0125 NC_012441.1 130413 131105 R porin complement(130413..131105) Brucella melitensis ATCC 23457 7676550 YP_002731892.1 CDS BMEA_A0126 NC_012441.1 131372 132058 R outer membrane protein complement(131372..132058) Brucella melitensis ATCC 23457 7676551 YP_002731893.1 CDS BMEA_A0127 NC_012441.1 132290 132907 R hypothetical protein complement(132290..132907) Brucella melitensis ATCC 23457 7676552 YP_002731894.1 CDS BMEA_A0128 NC_012441.1 132946 134361 R hypothetical protein complement(132946..134361) Brucella melitensis ATCC 23457 7676553 YP_002731895.1 CDS BMEA_A0129 NC_012441.1 134592 134840 D hypothetical protein 134592..134840 Brucella melitensis ATCC 23457 7676554 YP_002731896.1 CDS polA NC_012441.1 134922 137858 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 134922..137858 Brucella melitensis ATCC 23457 7676555 YP_002731897.1 CDS BMEA_A0131 NC_012441.1 138000 139880 D DEAD/DEAH box helicase 138000..139880 Brucella melitensis ATCC 23457 7676556 YP_002731898.1 CDS gyrB NC_012441.1 139976 142417 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(139976..142417) Brucella melitensis ATCC 23457 7676557 YP_002731899.1 CDS BMEA_A0133 NC_012441.1 142468 142635 R hypothetical protein complement(142468..142635) Brucella melitensis ATCC 23457 7676558 YP_002731900.1 CDS BMEA_A0137 NC_012441.1 144707 145819 R S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase complement(144707..145819) Brucella melitensis ATCC 23457 7676562 YP_002731901.1 CDS BMEA_A0138 NC_012441.1 145853 146209 R hypothetical protein complement(145853..146209) Brucella melitensis ATCC 23457 7676563 YP_002731902.1 CDS BMEA_A0140 NC_012441.1 148776 150068 D sensor histidine kinase regB 148776..150068 Brucella melitensis ATCC 23457 7676565 YP_002731903.1 CDS BMEA_A0141 NC_012441.1 150138 150506 D transposase 150138..150506 Brucella melitensis ATCC 23457 7676566 YP_002731904.1 CDS BMEA_A0142 NC_012441.1 150503 150781 D IS6501 transposase 150503..150781 Brucella melitensis ATCC 23457 7676567 YP_002731905.1 CDS BMEA_A0143 NC_012441.1 151496 152059 D photosynthetic apparatus regulatory protein regA 151496..152059 Brucella melitensis ATCC 23457 7676568 YP_002731906.1 CDS BMEA_A0144 NC_012441.1 152065 152367 R hypothetical protein complement(152065..152367) Brucella melitensis ATCC 23457 7676569 YP_002731907.1 CDS BMEA_A0145 NC_012441.1 152829 153449 D ErfK/YbiS/YcfS/YnhG family protein 152829..153449 Brucella melitensis ATCC 23457 7676570 YP_002731908.1 CDS BMEA_A0146 NC_012441.1 153539 154111 R NifU-like protein complement(153539..154111) Brucella melitensis ATCC 23457 7676571 YP_002731909.1 CDS BMEA_A0147 NC_012441.1 154220 154759 R UspA domain-containing protein complement(154220..154759) Brucella melitensis ATCC 23457 7676572 YP_002731910.1 CDS trpS NC_012441.1 154766 155923 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(154766..155923) Brucella melitensis ATCC 23457 7676573 YP_002731911.1 CDS mviN NC_012441.1 155930 157519 R integral membrane protein MviN complement(155930..157519) Brucella melitensis ATCC 23457 7676574 YP_002731912.1 CDS glnD NC_012441.1 157533 160337 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(157533..160337) Brucella melitensis ATCC 23457 7676575 YP_002731913.1 CDS BMEA_A0151 NC_012441.1 160403 160498 D hypothetical protein 160403..160498 Brucella melitensis ATCC 23457 7676576 YP_002731914.1 CDS mutS NC_012441.1 162930 165662 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 162930..165662 Brucella melitensis ATCC 23457 7676578 YP_002731915.1 CDS BMEA_A0154 NC_012441.1 165968 166861 R hypothetical protein complement(165968..166861) Brucella melitensis ATCC 23457 7676579 YP_002731916.1 CDS lspA NC_012441.1 167136 167618 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(167136..167618) Brucella melitensis ATCC 23457 7676580 YP_002731917.1 CDS BMEA_A0156 NC_012441.1 167620 168513 R tRNA/rRNA methyltransferase SpoU complement(167620..168513) Brucella melitensis ATCC 23457 7676581 YP_002731918.1 CDS BMEA_A0158 NC_012441.1 169767 170090 R hypothetical protein complement(169767..170090) Brucella melitensis ATCC 23457 7676583 YP_002731919.1 CDS ihfB NC_012441.1 170100 170384 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(170100..170384) Brucella melitensis ATCC 23457 7676584 YP_002731920.1 CDS sppA NC_012441.1 170431 171414 R signal peptide peptidase SppA, 36K type complement(170431..171414) Brucella melitensis ATCC 23457 7676585 YP_002731921.1 CDS BMEA_A0161 NC_012441.1 171876 172598 D hypothetical protein 171876..172598 Brucella melitensis ATCC 23457 7676586 YP_002731922.1 CDS BMEA_A0162 NC_012441.1 172922 173536 D OstA-like protein 172922..173536 Brucella melitensis ATCC 23457 7676587 YP_002731923.1 CDS BMEA_A0163 NC_012441.1 173548 174381 D ABC transporter ATP-binding protein 173548..174381 Brucella melitensis ATCC 23457 7676588 YP_002731924.1 CDS rpoN NC_012441.1 174677 176179 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 174677..176179 Brucella melitensis ATCC 23457 7676589 YP_002731925.1 CDS BMEA_A0165 NC_012441.1 176325 176693 R hypothetical protein complement(176325..176693) Brucella melitensis ATCC 23457 7676590 YP_002731926.1 CDS yfiA NC_012441.1 176929 177522 D ribosomal subunit interface protein 176929..177522 Brucella melitensis ATCC 23457 7676591 YP_002731927.1 CDS ptsN NC_012441.1 177625 178089 D PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 177625..178089 Brucella melitensis ATCC 23457 7676592 YP_002731928.1 CDS BMEA_A0168 NC_012441.1 178170 178415 R hypothetical protein complement(178170..178415) Brucella melitensis ATCC 23457 7676593 YP_002731929.1 CDS BMEA_A0169 NC_012441.1 178521 178943 R small heat shock protein hspD complement(178521..178943) Brucella melitensis ATCC 23457 7676594 YP_002731930.1 CDS BMEA_A0170 NC_012441.1 179034 179234 R hypothetical protein complement(179034..179234) Brucella melitensis ATCC 23457 7676595 YP_002731931.1 CDS BMEA_A0171 NC_012441.1 179215 179829 R hypothetical protein complement(179215..179829) Brucella melitensis ATCC 23457 7677395 YP_002731932.1 CDS nth NC_012441.1 179817 180563 D endonuclease III 179817..180563 Brucella melitensis ATCC 23457 7677396 YP_002731933.1 CDS BMEA_A0173 NC_012441.1 180604 181317 R putative role in sulfur assimilation; CysZ-like protein complement(180604..181317) Brucella melitensis ATCC 23457 7677397 YP_002731934.1 CDS BMEA_A0174 NC_012441.1 181314 181574 R hypothetical protein complement(181314..181574) Brucella melitensis ATCC 23457 7677398 YP_002731935.1 CDS BMEA_A0175 NC_012441.1 181577 182569 D fructokinase-2 181577..182569 Brucella melitensis ATCC 23457 7677399 YP_002731936.1 CDS BMEA_A0176 NC_012441.1 182588 183244 R hypothetical protein complement(182588..183244) Brucella melitensis ATCC 23457 7677400 YP_002731937.1 CDS BMEA_A0177 NC_012441.1 183377 184069 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(183377..184069) Brucella melitensis ATCC 23457 7677401 YP_002731938.1 CDS hrcA NC_012441.1 184175 185245 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(184175..185245) Brucella melitensis ATCC 23457 7677402 YP_002731939.1 CDS rph NC_012441.1 185467 186183 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 185467..186183 Brucella melitensis ATCC 23457 7677403 YP_002731940.1 CDS rdgB NC_012441.1 186763 187425 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 186763..187425 Brucella melitensis ATCC 23457 7677405 YP_002731941.1 CDS BMEA_A0183 NC_012441.1 187422 188636 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 187422..188636 Brucella melitensis ATCC 23457 7677406 YP_002731942.1 CDS BMEA_A0184 NC_012441.1 188648 189559 D hypothetical protein 188648..189559 Brucella melitensis ATCC 23457 7677407 YP_002731943.1 CDS BMEA_A0185 NC_012441.1 189556 189936 D hypothetical protein 189556..189936 Brucella melitensis ATCC 23457 7677408 YP_002731944.1 CDS cobA NC_012441.1 190162 191568 D uroporphyrin-III C-methyltransferase 190162..191568 Brucella melitensis ATCC 23457 7677409 YP_002731945.1 CDS BMEA_A0187 NC_012441.1 191586 191888 D hypothetical protein 191586..191888 Brucella melitensis ATCC 23457 7677410 YP_002731946.1 CDS BMEA_A0188 NC_012441.1 191909 193579 D sulfite reductase ferredoxin 191909..193579 Brucella melitensis ATCC 23457 7677411 YP_002731947.1 CDS cysH NC_012441.1 193569 194327 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 193569..194327 Brucella melitensis ATCC 23457 7677412 YP_002731948.1 CDS BMEA_A0190 NC_012441.1 194380 194904 D hypothetical protein 194380..194904 Brucella melitensis ATCC 23457 7677413 YP_002731949.1 CDS BMEA_A0191 NC_012441.1 194972 195265 D stress responsive alpha-beta barrel domain-containing protein 194972..195265 Brucella melitensis ATCC 23457 7677414 YP_002731950.1 CDS BMEA_A0192 NC_012441.1 195266 195844 R methylated-DNA--protein-cysteine methyltransferase complement(195266..195844) Brucella melitensis ATCC 23457 7677415 YP_002731951.1 CDS BMEA_A0194 NC_012441.1 196102 196347 D hypothetical protein 196102..196347 Brucella melitensis ATCC 23457 7677416 YP_002731952.1 CDS BMEA_A0195 NC_012441.1 196400 196789 R BA14K family protein complement(196400..196789) Brucella melitensis ATCC 23457 7677417 YP_002731953.1 CDS metH NC_012441.1 197103 200888 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 197103..200888 Brucella melitensis ATCC 23457 7677418 YP_002731954.1 CDS BMEA_A0198 NC_012441.1 201200 201916 D transcriptional activator protein solR 201200..201916 Brucella melitensis ATCC 23457 7677419 YP_002731955.1 CDS BMEA_A0199 NC_012441.1 202031 203401 D aminotransferase 202031..203401 Brucella melitensis ATCC 23457 7677420 YP_002731956.1 CDS BMEA_A0200 NC_012441.1 203483 203791 R hypothetical protein complement(203483..203791) Brucella melitensis ATCC 23457 7677421 YP_002731957.1 CDS cysD NC_012441.1 203804 204706 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 203804..204706 Brucella melitensis ATCC 23457 7677422 YP_002731958.1 CDS cysN NC_012441.1 204706 206640 D in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 204706..206640 Brucella melitensis ATCC 23457 7677423 YP_002731959.1 CDS cysQ NC_012441.1 206643 207488 D 3'(2'),5'-bisphosphate nucleotidase 206643..207488 Brucella melitensis ATCC 23457 7677424 YP_002731960.1 CDS BMEA_A0205 NC_012441.1 207750 208556 R fumarate nitrate reduction regulatory protein complement(207750..208556) Brucella melitensis ATCC 23457 7677426 YP_002731961.1 CDS BMEA_A0206 NC_012441.1 208754 209491 D monoamine regulon transcriptional regulator 208754..209491 Brucella melitensis ATCC 23457 7677427 YP_002731962.1 CDS BMEA_A0207 NC_012441.1 209466 209597 D hypothetical protein 209466..209597 Brucella melitensis ATCC 23457 7677428 YP_002731963.1 CDS BMEA_A0208 NC_012441.1 209819 210610 D DeoR family transcriptional regulator 209819..210610 Brucella melitensis ATCC 23457 7677429 YP_002731964.1 CDS BMEA_A0209 NC_012441.1 210692 212194 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 210692..212194 Brucella melitensis ATCC 23457 7677430 YP_002731965.1 CDS BMEA_A0210 NC_012441.1 212080 213381 D Fis family transcriptional regulator 212080..213381 Brucella melitensis ATCC 23457 7677431 YP_002731966.1 CDS BMEA_A0211 NC_012441.1 213530 215047 D EPTC-inducible aldehyde dehydrogenase 213530..215047 Brucella melitensis ATCC 23457 7677432 YP_002731967.1 CDS BMEA_A0212 NC_012441.1 215528 216562 D alcohol dehydrogenase 215528..216562 Brucella melitensis ATCC 23457 7677433 YP_002731968.1 CDS BMEA_A0213 NC_012441.1 216584 216985 D hypothetical protein 216584..216985 Brucella melitensis ATCC 23457 7677434 YP_002731969.1 CDS BMEA_A0214 NC_012441.1 217047 218069 D alanine racemase 217047..218069 Brucella melitensis ATCC 23457 7677435 YP_002731970.1 CDS BMEA_A0216 NC_012441.1 220427 220591 R hypothetical protein complement(220427..220591) Brucella melitensis ATCC 23457 7677437 YP_002731971.1 CDS BMEA_A0217 NC_012441.1 220580 222013 D aldehyde dehydrogenase family protein 220580..222013 Brucella melitensis ATCC 23457 7677438 YP_002731972.1 CDS BMEA_A0219 NC_012441.1 222830 223528 R transcriptional activator, TenA family protein complement(222830..223528) Brucella melitensis ATCC 23457 7677440 YP_002731973.1 CDS BMEA_A0220 NC_012441.1 223525 224493 R NMT1/THI5 like domain-containing protein complement(223525..224493) Brucella melitensis ATCC 23457 7677441 YP_002731974.1 CDS BMEA_A0221 NC_012441.1 224517 225128 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase complement(224517..225128) Brucella melitensis ATCC 23457 7677442 YP_002731975.1 CDS BMEA_A0222 NC_012441.1 225125 225895 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(225125..225895) Brucella melitensis ATCC 23457 7677443 YP_002731976.1 CDS thiS NC_012441.1 225897 226094 R thiamine biosynthesis protein ThiS complement(225897..226094) Brucella melitensis ATCC 23457 7677444 YP_002731977.1 CDS thiO NC_012441.1 226091 227095 R glycine oxidase ThiO complement(226091..227095) Brucella melitensis ATCC 23457 7677445 YP_002731978.1 CDS thiD NC_012441.1 227095 227970 R phosphomethylpyrimidine kinase complement(227095..227970) Brucella melitensis ATCC 23457 7677446 YP_002731979.1 CDS BMEA_A0227 NC_012441.1 228399 230510 D diguanylate cyclase GGDEF domain-containing protein 228399..230510 Brucella melitensis ATCC 23457 7677447 YP_002731980.1 CDS BMEA_A0228 NC_012441.1 230609 233089 D heavy metal translocating P-type ATPase 230609..233089 Brucella melitensis ATCC 23457 7677448 YP_002731981.1 CDS cueR NC_012441.1 233069 233518 R Cu (I) responsive transcriptional regulator complement(233069..233518) Brucella melitensis ATCC 23457 7677449 YP_002731982.1 CDS BMEA_A0230 NC_012441.1 233624 234370 R binding-protein-dependent transport systems inner membrane protein complement(233624..234370) Brucella melitensis ATCC 23457 7677450 YP_002731983.1 CDS BMEA_A0231 NC_012441.1 234367 235305 R ABC transporter complement(234367..235305) Brucella melitensis ATCC 23457 7677451 YP_002731984.1 CDS BMEA_A0232 NC_012441.1 235302 236462 R binding-protein-dependent transport systems inner membrane protein complement(235302..236462) Brucella melitensis ATCC 23457 7677452 YP_002731985.1 CDS BMEA_A0233 NC_012441.1 236535 237602 R glycine/betaine ABC transporter substrate-binding protein complement(236535..237602) Brucella melitensis ATCC 23457 7677453 YP_002731986.1 CDS BMEA_A0234 NC_012441.1 237635 238300 R hypothetical protein complement(237635..238300) Brucella melitensis ATCC 23457 7677454 YP_002731987.1 CDS BMEA_A0235 NC_012441.1 238589 239854 R glutamate dehydrogenase complement(238589..239854) Brucella melitensis ATCC 23457 7677455 YP_002731988.1 CDS BMEA_A0236 NC_012441.1 240045 240212 D hypothetical protein 240045..240212 Brucella melitensis ATCC 23457 7677456 YP_002731989.1 CDS BMEA_A0237 NC_012441.1 240181 241434 D sarcosine oxidase subunit beta 240181..241434 Brucella melitensis ATCC 23457 7677457 YP_002731990.1 CDS BMEA_A0238 NC_012441.1 241453 241758 D sarcosine oxidase subunit delta 241453..241758 Brucella melitensis ATCC 23457 7677458 YP_002731991.1 CDS BMEA_A0239 NC_012441.1 241758 244757 D sarcosine oxidase subunit alpha 241758..244757 Brucella melitensis ATCC 23457 7677459 YP_002731992.1 CDS BMEA_A0240 NC_012441.1 244768 245322 D sarcosine oxidase gamma subunit 244768..245322 Brucella melitensis ATCC 23457 7677460 YP_002731993.1 CDS BMEA_A0241 NC_012441.1 245375 246223 R amidohydrolase 2 complement(245375..246223) Brucella melitensis ATCC 23457 7677461 YP_002731994.1 CDS BMEA_A0242 NC_012441.1 246281 247075 R HTH-type transcriptional repressor AllR complement(246281..247075) Brucella melitensis ATCC 23457 7677462 YP_002731995.1 CDS BMEA_A0243 NC_012441.1 247233 248552 D extracellular solute-binding protein 247233..248552 Brucella melitensis ATCC 23457 7677463 YP_002731996.1 CDS BMEA_A0244 NC_012441.1 248613 249536 D binding-protein-dependent transport systems inner membrane protein 248613..249536 Brucella melitensis ATCC 23457 7677464 YP_002731997.1 CDS BMEA_A0245 NC_012441.1 249539 250414 D binding-protein-dependent transport systems inner membrane protein 249539..250414 Brucella melitensis ATCC 23457 7677465 YP_002731998.1 CDS BMEA_A0246 NC_012441.1 250422 251513 D lactose transport ATP-binding protein lacK 250422..251513 Brucella melitensis ATCC 23457 7677466 YP_002731999.1 CDS BMEA_A0247 NC_012441.1 251516 252634 D mandelate racemase 251516..252634 Brucella melitensis ATCC 23457 7677467 YP_002732000.1 CDS BMEA_A0248 NC_012441.1 252631 252975 D hypothetical protein 252631..252975 Brucella melitensis ATCC 23457 7677468 YP_002732001.1 CDS BMEA_A0249 NC_012441.1 252968 254047 D trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 252968..254047 Brucella melitensis ATCC 23457 7677469 YP_002732002.1 CDS BMEA_A0250 NC_012441.1 254050 254148 D hypothetical protein 254050..254148 Brucella melitensis ATCC 23457 7677470 YP_002732003.1 CDS BMEA_A0251 NC_012441.1 254152 254886 D short-chain dehydrogenase/reductase SDR 254152..254886 Brucella melitensis ATCC 23457 7677471 YP_002732004.1 CDS BMEA_A0252 NC_012441.1 254927 255772 D fumarylacetoacetate hydrolase domain-containing protein 2 254927..255772 Brucella melitensis ATCC 23457 7677472 YP_002732005.1 CDS BMEA_A0253 NC_012441.1 255786 257063 D mandelate racemase/muconate lactonizing enzyme domain-containing protein 255786..257063 Brucella melitensis ATCC 23457 7677473 YP_002732006.1 CDS BMEA_A0254 NC_012441.1 257224 257307 R hypothetical protein complement(257224..257307) Brucella melitensis ATCC 23457 7677474 YP_002732007.1 CDS BMEA_A0255 NC_012441.1 257462 258013 R hypothetical protein complement(257462..258013) Brucella melitensis ATCC 23457 7677475 YP_002732008.1 CDS BMEA_A0256 NC_012441.1 258842 258967 R hypothetical protein complement(258842..258967) Brucella melitensis ATCC 23457 7677964 YP_002732009.1 CDS BMEA_A0257 NC_012441.1 259204 260400 D putative integrase DNA protein 259204..260400 Brucella melitensis ATCC 23457 7677965 YP_002732010.1 CDS BMEA_A0258 NC_012441.1 260538 260810 R hypothetical protein complement(260538..260810) Brucella melitensis ATCC 23457 7677966 YP_002732011.1 CDS BMEA_A0259 NC_012441.1 260911 261129 D hypothetical protein 260911..261129 Brucella melitensis ATCC 23457 7677967 YP_002732012.1 CDS BMEA_A0260 NC_012441.1 261336 261650 D hypothetical protein 261336..261650 Brucella melitensis ATCC 23457 7677968 YP_002732013.1 CDS BMEA_A0261 NC_012441.1 261647 262528 D hypothetical protein 261647..262528 Brucella melitensis ATCC 23457 7677969 YP_002732014.1 CDS BMEA_A0262 NC_012441.1 262525 264027 D hypothetical protein 262525..264027 Brucella melitensis ATCC 23457 7677970 YP_002732015.1 CDS BMEA_A0263 NC_012441.1 264054 264641 D hypothetical protein 264054..264641 Brucella melitensis ATCC 23457 7677971 YP_002732016.1 CDS BMEA_A0264 NC_012441.1 264634 264798 D hypothetical protein 264634..264798 Brucella melitensis ATCC 23457 7677972 YP_002732017.1 CDS BMEA_A0265 NC_012441.1 264795 265811 D hypothetical protein 264795..265811 Brucella melitensis ATCC 23457 7677973 YP_002732018.1 CDS BMEA_A0266 NC_012441.1 265913 266122 D hypothetical protein 265913..266122 Brucella melitensis ATCC 23457 7677974 YP_002732019.1 CDS BMEA_A0268 NC_012441.1 268236 270281 D elastin 268236..270281 Brucella melitensis ATCC 23457 7677976 YP_002732020.1 CDS BMEA_A0269 NC_012441.1 270264 270446 R hypothetical protein complement(270264..270446) Brucella melitensis ATCC 23457 7677977 YP_002732021.1 CDS BMEA_A0270 NC_012441.1 270482 270787 D hypothetical protein 270482..270787 Brucella melitensis ATCC 23457 7677978 YP_002732022.1 CDS BMEA_A0271 NC_012441.1 271886 272092 D hypothetical protein 271886..272092 Brucella melitensis ATCC 23457 7677979 YP_002732023.1 CDS BMEA_A0272 NC_012441.1 273999 274178 R hypothetical protein complement(273999..274178) Brucella melitensis ATCC 23457 7677980 YP_002732024.1 CDS BMEA_A0273 NC_012441.1 275310 275555 R helix-turn-helix domain-containing protein complement(275310..275555) Brucella melitensis ATCC 23457 7677981 YP_002732025.1 CDS BMEA_A0274 NC_012441.1 275633 275878 D hypothetical protein 275633..275878 Brucella melitensis ATCC 23457 7677982 YP_002732026.1 CDS BMEA_A0275 NC_012441.1 275944 276234 D hypothetical protein 275944..276234 Brucella melitensis ATCC 23457 7677983 YP_002732027.1 CDS BMEA_A0276 NC_012441.1 276231 276770 D hypothetical protein 276231..276770 Brucella melitensis ATCC 23457 7677984 YP_002732028.1 CDS BMEA_A0277 NC_012441.1 276871 277044 D hypothetical protein 276871..277044 Brucella melitensis ATCC 23457 7677985 YP_002732029.1 CDS BMEA_A0278 NC_012441.1 277041 277649 D hypothetical protein 277041..277649 Brucella melitensis ATCC 23457 7677986 YP_002732030.1 CDS BMEA_A0279 NC_012441.1 278349 279176 R hypothetical protein complement(278349..279176) Brucella melitensis ATCC 23457 7677987 YP_002732031.1 CDS BMEA_A0280 NC_012441.1 279415 279549 D hypothetical protein 279415..279549 Brucella melitensis ATCC 23457 7677988 YP_002732032.1 CDS BMEA_A0282 NC_012441.1 280156 280371 R zinc-binding protein complement(280156..280371) Brucella melitensis ATCC 23457 7677990 YP_002732033.1 CDS maf NC_012441.1 280381 281007 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(280381..281007) Brucella melitensis ATCC 23457 7677991 YP_002732034.1 CDS infA NC_012441.1 281041 281259 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(281041..281259) Brucella melitensis ATCC 23457 7677992 YP_002732035.1 CDS BMEA_A0285 NC_012441.1 281371 281844 R protein tyrosine phosphatase complement(281371..281844) Brucella melitensis ATCC 23457 7677993 YP_002732036.1 CDS BMEA_A0286 NC_012441.1 281851 282333 R hypothetical protein complement(281851..282333) Brucella melitensis ATCC 23457 7677994 YP_002732037.1 CDS hisD NC_012441.1 282340 283632 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(282340..283632) Brucella melitensis ATCC 23457 7677995 YP_002732038.1 CDS BMEA_A0288 NC_012441.1 283707 284147 R hypothetical protein complement(283707..284147) Brucella melitensis ATCC 23457 7677996 YP_002732039.1 CDS murA NC_012441.1 284418 285707 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(284418..285707) Brucella melitensis ATCC 23457 7677997 YP_002732040.1 CDS BMEA_A0290 NC_012441.1 285930 286109 R hypothetical protein complement(285930..286109) Brucella melitensis ATCC 23457 7677998 YP_002732041.1 CDS BMEA_A0292 NC_012441.1 286412 288178 D hypothetical protein 286412..288178 Brucella melitensis ATCC 23457 7678000 YP_002732042.1 CDS BMEA_A0293 NC_012441.1 288273 288695 D BRO family protein 288273..288695 Brucella melitensis ATCC 23457 7678001 YP_002732043.1 CDS BMEA_A0294 NC_012441.1 289064 289213 D hypothetical protein 289064..289213 Brucella melitensis ATCC 23457 7678002 YP_002732044.1 CDS BMEA_A0295 NC_012441.1 289493 290110 D DNA-invertase 289493..290110 Brucella melitensis ATCC 23457 7678003 YP_002732045.1 CDS BMEA_A0296 NC_012441.1 290668 292032 D hypothetical protein 290668..292032 Brucella melitensis ATCC 23457 7678004 YP_002732046.1 CDS BMEA_A0297 NC_012441.1 293335 293619 R hypothetical protein complement(293335..293619) Brucella melitensis ATCC 23457 7678005 YP_002732047.1 CDS BMEA_A0298 NC_012441.1 293733 293996 R hypothetical protein complement(293733..293996) Brucella melitensis ATCC 23457 7678006 YP_002732048.1 CDS BMEA_A0299 NC_012441.1 294080 294469 D hypothetical protein 294080..294469 Brucella melitensis ATCC 23457 7678007 YP_002732049.1 CDS BMEA_A0300 NC_012441.1 295061 295903 D urease accessory protein UreD 295061..295903 Brucella melitensis ATCC 23457 7678008 YP_002732050.1 CDS ureA NC_012441.1 296056 296358 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 296056..296358 Brucella melitensis ATCC 23457 7678009 YP_002732051.1 CDS ureB NC_012441.1 296525 296830 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 296525..296830 Brucella melitensis ATCC 23457 7678010 YP_002732052.1 CDS ureC NC_012441.1 296849 298561 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 296849..298561 Brucella melitensis ATCC 23457 7678011 YP_002732053.1 CDS BMEA_A0304 NC_012441.1 298577 299065 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 298577..299065 Brucella melitensis ATCC 23457 7678012 YP_002732054.1 CDS BMEA_A0305 NC_012441.1 299037 299723 D urease accessory protein UreF 299037..299723 Brucella melitensis ATCC 23457 7678013 YP_002732055.1 CDS ureG NC_012441.1 299720 300346 D urease accessory protein UreG 299720..300346 Brucella melitensis ATCC 23457 7678014 YP_002732056.1 CDS BMEA_A0308 NC_012441.1 300703 302328 R integral membrane sensor signal transduction histidine kinase complement(300703..302328) Brucella melitensis ATCC 23457 7678016 YP_002732057.1 CDS BMEA_A0310 NC_012441.1 302613 303764 D RND family efflux transporter 302613..303764 Brucella melitensis ATCC 23457 7678017 YP_002732058.1 CDS BMEA_A0311 NC_012441.1 303779 306910 D acriflavin resistance protein 303779..306910 Brucella melitensis ATCC 23457 7678018 YP_002732059.1 CDS hydA NC_012441.1 307033 308502 R catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase complement(307033..308502) Brucella melitensis ATCC 23457 7678019 YP_002732060.1 CDS BMEA_A0313 NC_012441.1 308554 309801 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(308554..309801) Brucella melitensis ATCC 23457 7678020 YP_002732061.1 CDS BMEA_A0315 NC_012441.1 310700 311089 D nudix domain-containing protein 310700..311089 Brucella melitensis ATCC 23457 7678022 YP_002732062.1 CDS BMEA_A0316 NC_012441.1 311134 312444 R catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase complement(311134..312444) Brucella melitensis ATCC 23457 7678023 YP_002732063.1 CDS BMEA_A0317 NC_012441.1 312448 313944 R function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase complement(312448..313944) Brucella melitensis ATCC 23457 7678024 YP_002732064.1 CDS BMEA_A0319 NC_012441.1 314132 314584 R carbon monoxide dehydrogenase subunit G complement(314132..314584) Brucella melitensis ATCC 23457 7678025 YP_002732065.1 CDS BMEA_A0320 NC_012441.1 314735 316384 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 314735..316384 Brucella melitensis ATCC 23457 7678026 YP_002732066.1 CDS BMEA_A0321 NC_012441.1 316518 317579 D succinylglutamate desuccinylase/aspartoacylase 316518..317579 Brucella melitensis ATCC 23457 7678027 YP_002732067.1 CDS BMEA_A0322 NC_012441.1 317576 318325 D HAD-superfamily hydrolase 317576..318325 Brucella melitensis ATCC 23457 7678028 YP_002732068.1 CDS BMEA_A0323 NC_012441.1 318298 319170 R hypothetical protein complement(318298..319170) Brucella melitensis ATCC 23457 7678029 YP_002732069.1 CDS BMEA_A0324 NC_012441.1 319196 320941 R activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(319196..320941) Brucella melitensis ATCC 23457 7678030 YP_002732070.1 CDS BMEA_A0325 NC_012441.1 321292 321921 R HTH-type transcriptional regulator TtgR complement(321292..321921) Brucella melitensis ATCC 23457 7678031 YP_002732071.1 CDS BMEA_A0327 NC_012441.1 322094 323287 D RND family efflux transporter 322094..323287 Brucella melitensis ATCC 23457 7678032 YP_002732072.1 CDS BMEA_A0328 NC_012441.1 323284 326439 D hydrophobe/amphiphile efflux protein 323284..326439 Brucella melitensis ATCC 23457 7678033 YP_002732073.1 CDS BMEA_A0329 NC_012441.1 326550 326717 R hypothetical protein complement(326550..326717) Brucella melitensis ATCC 23457 7678034 YP_002732074.1 CDS BMEA_A0330 NC_012441.1 326938 327078 R hypothetical protein complement(326938..327078) Brucella melitensis ATCC 23457 7678035 YP_002732075.1 CDS BMEA_A0331 NC_012441.1 327147 327989 R family 3 extracellular solute-binding protein complement(327147..327989) Brucella melitensis ATCC 23457 7678036 YP_002732076.1 CDS BMEA_A0332 NC_012441.1 328255 330147 D xyloglucan glycosyltransferase 1 328255..330147 Brucella melitensis ATCC 23457 7678037 YP_002732077.1 CDS BMEA_A0333 NC_012441.1 330075 331034 R hypothetical protein complement(330075..331034) Brucella melitensis ATCC 23457 7678038 YP_002732078.1 CDS BMEA_A0334 NC_012441.1 331167 332483 D histidine kinase 331167..332483 Brucella melitensis ATCC 23457 7678039 YP_002732079.1 CDS BMEA_A0335 NC_012441.1 332613 333155 R GcrA cell cycle regulator complement(332613..333155) Brucella melitensis ATCC 23457 7678040 YP_002732080.1 CDS argD NC_012441.1 333759 334970 D DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase protein 333759..334970 Brucella melitensis ATCC 23457 7678041 YP_002732081.1 CDS argF NC_012441.1 334975 335913 D catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 334975..335913 Brucella melitensis ATCC 23457 7678042 YP_002732082.1 CDS BMEA_A0338 NC_012441.1 335915 336937 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 335915..336937 Brucella melitensis ATCC 23457 7678043 YP_002732083.1 CDS BMEA_A0339 NC_012441.1 336978 337370 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(336978..337370) Brucella melitensis ATCC 23457 7678044 YP_002732084.1 CDS metZ NC_012441.1 337739 338935 R catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; O-succinylhomoserine sulfhydrylase complement(337739..338935) Brucella melitensis ATCC 23457 7677478 YP_002732085.1 CDS BMEA_A0343 NC_012441.1 339362 340453 D Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 339362..340453 Brucella melitensis ATCC 23457 7677479 YP_002732086.1 CDS BMEA_A0344 NC_012441.1 340544 341560 D AraC family transcriptional regulator 340544..341560 Brucella melitensis ATCC 23457 7677480 YP_002732087.1 CDS BMEA_A0345 NC_012441.1 341647 341913 D hypothetical protein 341647..341913 Brucella melitensis ATCC 23457 7677481 YP_002732088.1 CDS BMEA_A0346 NC_012441.1 341950 342432 D hypothetical protein 341950..342432 Brucella melitensis ATCC 23457 7677482 YP_002732089.1 CDS BMEA_A0347 NC_012441.1 342607 343974 D MATE efflux family protein 342607..343974 Brucella melitensis ATCC 23457 7677483 YP_002732090.1 CDS pyrD NC_012441.1 343976 345070 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(343976..345070) Brucella melitensis ATCC 23457 7677484 YP_002732091.1 CDS BMEA_A0349 NC_012441.1 345067 345420 R hypothetical protein complement(345067..345420) Brucella melitensis ATCC 23457 7677485 YP_002732092.1 CDS BMEA_A0351 NC_012441.1 345674 346129 D hypothetical protein 345674..346129 Brucella melitensis ATCC 23457 7677486 YP_002732093.1 CDS pip NC_012441.1 346220 347170 R proline iminopeptidase complement(346220..347170) Brucella melitensis ATCC 23457 7677487 YP_002732094.1 CDS BMEA_A0353 NC_012441.1 347400 348041 D LuxR family two component transcriptional regulator 347400..348041 Brucella melitensis ATCC 23457 7677488 YP_002732095.1 CDS BMEA_A0354 NC_012441.1 348078 351602 R integral membrane sensor hybrid histidine kinase complement(348078..351602) Brucella melitensis ATCC 23457 7677489 YP_002732096.1 CDS BMEA_A0355 NC_012441.1 351887 352033 R hypothetical protein complement(351887..352033) Brucella melitensis ATCC 23457 7677490 YP_002732097.1 CDS mscL NC_012441.1 352115 352531 D homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 352115..352531 Brucella melitensis ATCC 23457 7677491 YP_002732098.1 CDS hemA NC_012441.1 352607 353884 R catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase complement(352607..353884) Brucella melitensis ATCC 23457 7677492 YP_002732099.1 CDS BMEA_A0358 NC_012441.1 354030 354731 R polysaccharide deacetylase complement(354030..354731) Brucella melitensis ATCC 23457 7677493 YP_002732100.1 CDS BMEA_A0359 NC_012441.1 354740 355459 R glycosyltransferase 25 family protein complement(354740..355459) Brucella melitensis ATCC 23457 7677494 YP_002732101.1 CDS BMEA_A0361 NC_012441.1 356354 356587 R hypothetical protein complement(356354..356587) Brucella melitensis ATCC 23457 7677496 YP_002732102.1 CDS BMEA_A0362 NC_012441.1 356630 357520 R LysR family transcriptional regulator complement(356630..357520) Brucella melitensis ATCC 23457 7677497 YP_002732103.1 CDS BMEA_A0363 NC_012441.1 357642 358061 D LrgA family protein 357642..358061 Brucella melitensis ATCC 23457 7677498 YP_002732104.1 CDS BMEA_A0364 NC_012441.1 358048 358755 D LrgB family protein 358048..358755 Brucella melitensis ATCC 23457 7677499 YP_002732105.1 CDS BMEA_A0365 NC_012441.1 358929 359264 D hypothetical protein 358929..359264 Brucella melitensis ATCC 23457 7677500 YP_002732106.1 CDS BMEA_A0366 NC_012441.1 359302 360543 D hypothetical protein 359302..360543 Brucella melitensis ATCC 23457 7677501 YP_002732107.1 CDS panC NC_012441.1 360630 361511 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 360630..361511 Brucella melitensis ATCC 23457 7677502 YP_002732108.1 CDS panB NC_012441.1 361513 362340 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 361513..362340 Brucella melitensis ATCC 23457 7677503 YP_002732109.1 CDS BMEA_A0369 NC_012441.1 362537 363313 R oxidoreductase FAD-binding domain-containing protein complement(362537..363313) Brucella melitensis ATCC 23457 7677504 YP_002732110.1 CDS BMEA_A0370 NC_012441.1 363717 364070 D hypothetical protein 363717..364070 Brucella melitensis ATCC 23457 7677505 YP_002732111.1 CDS nspC NC_012441.1 364109 365206 D carboxynorspermidine decarboxylase 364109..365206 Brucella melitensis ATCC 23457 7677506 YP_002732112.1 CDS BMEA_A0372 NC_012441.1 365387 366628 D hypothetical protein 365387..366628 Brucella melitensis ATCC 23457 7677507 YP_002732113.1 CDS BMEA_A0373 NC_012441.1 366644 366859 R hypothetical protein complement(366644..366859) Brucella melitensis ATCC 23457 7677508 YP_002732114.1 CDS BMEA_A0374 NC_012441.1 366884 367912 R proline racemase A complement(366884..367912) Brucella melitensis ATCC 23457 7677509 YP_002732115.1 CDS BMEA_A0375 NC_012441.1 368365 369780 D MATE efflux family protein 368365..369780 Brucella melitensis ATCC 23457 7677510 YP_002732116.1 CDS BMEA_A0376 NC_012441.1 369826 370380 R invasion associated locus B family protein complement(369826..370380) Brucella melitensis ATCC 23457 7677511 YP_002732117.1 CDS BMEA_A0377 NC_012441.1 370589 371962 D integral membrane sensor signal transduction histidine kinase 370589..371962 Brucella melitensis ATCC 23457 7677512 YP_002732118.1 CDS BMEA_A0378 NC_012441.1 371959 372600 D LuxR family two component transcriptional regulator 371959..372600 Brucella melitensis ATCC 23457 7677513 YP_002732119.1 CDS BMEA_A0379 NC_012441.1 372751 372861 D hypothetical protein 372751..372861 Brucella melitensis ATCC 23457 7677514 YP_002732120.1 CDS BMEA_A0380 NC_012441.1 372888 373436 D hypothetical protein 372888..373436 Brucella melitensis ATCC 23457 7677515 YP_002732121.1 CDS BMEA_A0381 NC_012441.1 373448 375016 D TRAP C4-dicarboxylate transport system permease DctM 373448..375016 Brucella melitensis ATCC 23457 7677516 YP_002732122.1 CDS BMEA_A0382 NC_012441.1 375078 376187 D RAP dicarboxylate transporter subunit DctP 375078..376187 Brucella melitensis ATCC 23457 7677517 YP_002732123.1 CDS BMEA_A0383 NC_012441.1 376270 377088 R hypothetical protein complement(376270..377088) Brucella melitensis ATCC 23457 7677518 YP_002732124.1 CDS BMEA_A0384 NC_012441.1 377101 378528 R urate catabolism protein complement(377101..378528) Brucella melitensis ATCC 23457 7677519 YP_002732125.1 CDS BMEA_A0385 NC_012441.1 378795 379070 D hypothetical protein 378795..379070 Brucella melitensis ATCC 23457 7677520 YP_002732126.1 CDS xdhA NC_012441.1 379076 380551 D xanthine dehydrogenase small subunit 379076..380551 Brucella melitensis ATCC 23457 7677521 YP_002732127.1 CDS xdhB NC_012441.1 380564 382909 D xanthine dehydrogenase molybdopterin binding subunit 380564..382909 Brucella melitensis ATCC 23457 7677522 YP_002732128.1 CDS xdhC NC_012441.1 382914 383786 D xanthine dehydrogenase accessory protein XdhC 382914..383786 Brucella melitensis ATCC 23457 7677523 YP_002732129.1 CDS BMEA_A0389 NC_012441.1 383867 384769 R LysR family transcriptional regulator complement(383867..384769) Brucella melitensis ATCC 23457 7677524 YP_002732130.1 CDS BMEA_A0390 NC_012441.1 384950 386203 D hypothetical protein 384950..386203 Brucella melitensis ATCC 23457 7677525 YP_002732131.1 CDS guaD NC_012441.1 386200 387504 D Catalyzes the deamination of guanine; guanine deaminase 386200..387504 Brucella melitensis ATCC 23457 7677526 YP_002732132.1 CDS BMEA_A0392 NC_012441.1 387584 388870 D hydroxypyruvate reductase 387584..388870 Brucella melitensis ATCC 23457 7677527 YP_002732133.1 CDS ccoS NC_012441.1 388851 389009 R cbb3-type cytochrome maturation protein complement(388851..389009) Brucella melitensis ATCC 23457 7677528 YP_002732134.1 CDS BMEA_A0394 NC_012441.1 389006 391264 R heavy metal translocating P-type ATPase complement(389006..391264) Brucella melitensis ATCC 23457 7677529 YP_002732135.1 CDS BMEA_A0395 NC_012441.1 391261 391758 R FixH family protein complement(391261..391758) Brucella melitensis ATCC 23457 7677530 YP_002732136.1 CDS ccoG NC_012441.1 391758 393308 R cytochrome c oxidase accessory protein CcoG complement(391758..393308) Brucella melitensis ATCC 23457 7677531 YP_002732137.1 CDS ccoP NC_012441.1 393476 394339 R cbb3-type cytochrome c oxidase subunit III complement(393476..394339) Brucella melitensis ATCC 23457 7677532 YP_002732138.1 CDS BMEA_A0398 NC_012441.1 394332 394490 R cbb3-type cytochrome oxidase subunit complement(394332..394490) Brucella melitensis ATCC 23457 7677533 YP_002732139.1 CDS ccoO NC_012441.1 394505 395236 R CcoO; FixO; cbb3-type cytochrome c oxidase subunit II complement(394505..395236) Brucella melitensis ATCC 23457 7677534 YP_002732140.1 CDS ccoN NC_012441.1 395251 396876 R CcoN; FixN; cbb3-type cytochrome c oxidase subunit I complement(395251..396876) Brucella melitensis ATCC 23457 7677535 YP_002732141.1 CDS BMEA_A0401 NC_012441.1 397094 397552 R ferric uptake regulation protein complement(397094..397552) Brucella melitensis ATCC 23457 7677536 YP_002732142.1 CDS BMEA_A0402 NC_012441.1 397551 397871 D hypothetical protein 397551..397871 Brucella melitensis ATCC 23457 7677537 YP_002732143.1 CDS BMEA_A0403 NC_012441.1 397983 398597 D DSBA oxidoreductase 397983..398597 Brucella melitensis ATCC 23457 7677538 YP_002732144.1 CDS BMEA_A0405 NC_012441.1 400289 401374 D methylated-DNA--protein-cysteine methyltransferase 400289..401374 Brucella melitensis ATCC 23457 7677540 YP_002732145.1 CDS BMEA_A0406 NC_012441.1 401556 401906 D hypothetical protein 401556..401906 Brucella melitensis ATCC 23457 7677541 YP_002732146.1 CDS BMEA_A0407 NC_012441.1 402243 403286 D hypothetical protein 402243..403286 Brucella melitensis ATCC 23457 7677542 YP_002732147.1 CDS BMEA_A0408 NC_012441.1 403436 404620 D hypothetical protein 403436..404620 Brucella melitensis ATCC 23457 7677543 YP_002732148.1 CDS BMEA_A0409 NC_012441.1 404842 406203 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 404842..406203 Brucella melitensis ATCC 23457 7677544 YP_002732149.1 CDS BMEA_A0410 NC_012441.1 406127 407125 R polysaccharide deacetylase complement(406127..407125) Brucella melitensis ATCC 23457 7677545 YP_002732150.1 CDS BMEA_A0411 NC_012441.1 407371 408042 D hypothetical protein 407371..408042 Brucella melitensis ATCC 23457 7677546 YP_002732151.1 CDS BMEA_A0412 NC_012441.1 408064 409515 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 408064..409515 Brucella melitensis ATCC 23457 7677547 YP_002732152.1 CDS BMEA_A0413 NC_012441.1 409674 410990 D Hsp70 family protein 409674..410990 Brucella melitensis ATCC 23457 7677548 YP_002732153.1 CDS BMEA_A0414 NC_012441.1 411427 412716 D cell wall hydrolase SleB 411427..412716 Brucella melitensis ATCC 23457 7677549 YP_002732154.1 CDS BMEA_A0415 NC_012441.1 412987 413385 D hypothetical protein 412987..413385 Brucella melitensis ATCC 23457 7677550 YP_002732155.1 CDS atpB NC_012441.1 413493 414242 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 413493..414242 Brucella melitensis ATCC 23457 7677551 YP_002732156.1 CDS BMEA_A0417 NC_012441.1 414310 414537 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 414310..414537 Brucella melitensis ATCC 23457 7677552 YP_002732157.1 CDS BMEA_A0418 NC_012441.1 414709 415335 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 414709..415335 Brucella melitensis ATCC 23457 7677553 YP_002732158.1 CDS atpF NC_012441.1 415346 415825 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 415346..415825 Brucella melitensis ATCC 23457 7677554 YP_002732159.1 CDS BMEA_A0420 NC_012441.1 415948 416610 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(415948..416610) Brucella melitensis ATCC 23457 7677555 YP_002732160.1 CDS BMEA_A0421 NC_012441.1 416787 417953 R radical SAM domain-containing protein complement(416787..417953) Brucella melitensis ATCC 23457 7677556 YP_002732161.1 CDS BMEA_A0422 NC_012441.1 418089 418595 D hypothetical protein 418089..418595 Brucella melitensis ATCC 23457 7677557 YP_002732162.1 CDS BMEA_A0423 NC_012441.1 418675 418941 R hypothetical protein complement(418675..418941) Brucella melitensis ATCC 23457 7677558 YP_002732163.1 CDS BMEA_A0424 NC_012441.1 419013 419225 R hypothetical protein complement(419013..419225) Brucella melitensis ATCC 23457 7676282 YP_002732164.1 CDS ispE NC_012441.1 419300 420199 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(419300..420199) Brucella melitensis ATCC 23457 7676283 YP_002732165.1 CDS BMEA_A0427 NC_012441.1 420229 420450 R hypothetical protein complement(420229..420450) Brucella melitensis ATCC 23457 7676730 YP_002732166.1 CDS nhaA NC_012441.1 420881 423172 R Na+/H+ antiporter NhaA complement(420881..423172) Brucella melitensis ATCC 23457 7676731 YP_002732167.1 CDS BMEA_A0429 NC_012441.1 423111 423326 R hypothetical protein complement(423111..423326) Brucella melitensis ATCC 23457 7676732 YP_002732168.1 CDS BMEA_A0430 NC_012441.1 423381 424163 R methyltransferase small complement(423381..424163) Brucella melitensis ATCC 23457 7676733 YP_002732169.1 CDS BMEA_A0431 NC_012441.1 424160 424387 R hypothetical protein complement(424160..424387) Brucella melitensis ATCC 23457 7676734 YP_002732170.1 CDS BMEA_A0432 NC_012441.1 424650 425672 D hypothetical protein 424650..425672 Brucella melitensis ATCC 23457 7676735 YP_002732171.1 CDS BMEA_A0433 NC_012441.1 425976 427841 D hypothetical protein 425976..427841 Brucella melitensis ATCC 23457 7676736 YP_002732172.1 CDS glyQ NC_012441.1 427993 428919 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 427993..428919 Brucella melitensis ATCC 23457 7676737 YP_002732173.1 CDS glyS NC_012441.1 428925 431258 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 428925..431258 Brucella melitensis ATCC 23457 7676738 YP_002732174.1 CDS BMEA_A0436 NC_012441.1 431397 432368 D Sua5/YciO/YrdC/YwlC family protein 431397..432368 Brucella melitensis ATCC 23457 7676739 YP_002732175.1 CDS BMEA_A0437 NC_012441.1 432394 433806 D hypothetical protein 432394..433806 Brucella melitensis ATCC 23457 7676740 YP_002732176.1 CDS BMEA_A0438 NC_012441.1 433844 434161 R plasmid stabilization system complement(433844..434161) Brucella melitensis ATCC 23457 7676741 YP_002732177.1 CDS BMEA_A0439 NC_012441.1 434158 434418 R CopG-like DNA-binding protein complement(434158..434418) Brucella melitensis ATCC 23457 7676742 YP_002732178.1 CDS BMEA_A0440 NC_012441.1 434527 434739 R hypothetical protein complement(434527..434739) Brucella melitensis ATCC 23457 7676743 YP_002732179.1 CDS BMEA_A0441 NC_012441.1 434729 435295 D hypothetical protein 434729..435295 Brucella melitensis ATCC 23457 7676744 YP_002732180.1 CDS BMEA_A0442 NC_012441.1 435438 436190 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(435438..436190) Brucella melitensis ATCC 23457 7676745 YP_002732181.1 CDS BMEA_A0443 NC_012441.1 436193 437971 R acyl-CoA dehydrogenase domain-containing protein complement(436193..437971) Brucella melitensis ATCC 23457 7676746 YP_002732182.1 CDS BMEA_A0444 NC_012441.1 438289 439434 D diguanylate cyclase GGDEF domain-containing protein 438289..439434 Brucella melitensis ATCC 23457 7676747 YP_002732183.1 CDS purD NC_012441.1 439452 440735 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(439452..440735) Brucella melitensis ATCC 23457 7676748 YP_002732184.1 CDS ubiA NC_012441.1 440880 441881 D UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 440880..441881 Brucella melitensis ATCC 23457 7676749 YP_002732185.1 CDS pdxH NC_012441.1 441921 442532 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(441921..442532) Brucella melitensis ATCC 23457 7676750 YP_002732186.1 CDS BMEA_A0449 NC_012441.1 443420 444361 D chaperone protein DnaJ 443420..444361 Brucella melitensis ATCC 23457 7676752 YP_002732187.1 CDS BMEA_A0450 NC_012441.1 444365 444472 R hypothetical protein complement(444365..444472) Brucella melitensis ATCC 23457 7676753 YP_002732188.1 CDS BMEA_A0451 NC_012441.1 444505 445323 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 444505..445323 Brucella melitensis ATCC 23457 7676754 YP_002732189.1 CDS BMEA_A0452 NC_012441.1 445837 446028 D phosphoglycerate mutase 445837..446028 Brucella melitensis ATCC 23457 7676755 YP_002732190.1 CDS BMEA_A0454 NC_012441.1 446290 446499 D ATP/GTP-binding domain-containing protein 446290..446499 Brucella melitensis ATCC 23457 7676756 YP_002732191.1 CDS BMEA_A0455 NC_012441.1 446597 446746 R hypothetical protein complement(446597..446746) Brucella melitensis ATCC 23457 7676757 YP_002732192.1 CDS BMEA_A0456 NC_012441.1 446969 447181 D hypothetical protein 446969..447181 Brucella melitensis ATCC 23457 7676758 YP_002732193.1 CDS BMEA_A0457 NC_012441.1 447258 447935 D hypothetical protein 447258..447935 Brucella melitensis ATCC 23457 7676759 YP_002732194.1 CDS BMEA_A0458 NC_012441.1 447971 448105 D hypothetical protein 447971..448105 Brucella melitensis ATCC 23457 7676760 YP_002732195.1 CDS BMEA_A0459 NC_012441.1 448080 448331 R hypothetical protein complement(448080..448331) Brucella melitensis ATCC 23457 7676761 YP_002732196.1 CDS BMEA_A0460 NC_012441.1 448455 448556 D hypothetical protein 448455..448556 Brucella melitensis ATCC 23457 7676762 YP_002732197.1 CDS aroC NC_012441.1 448605 449699 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 448605..449699 Brucella melitensis ATCC 23457 7676763 YP_002732198.1 CDS ribB NC_012441.1 449835 450950 D 3,4-dihydroxy-2-butanone 4-phosphate synthase 449835..450950 Brucella melitensis ATCC 23457 7676764 YP_002732199.1 CDS BMEA_A0463 NC_012441.1 451166 452116 D histone deacetylase superfamily protein 451166..452116 Brucella melitensis ATCC 23457 7676765 YP_002732200.1 CDS xseB NC_012441.1 452121 452375 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 452121..452375 Brucella melitensis ATCC 23457 7676766 YP_002732201.1 CDS BMEA_A0465 NC_012441.1 452382 452900 R hypothetical protein complement(452382..452900) Brucella melitensis ATCC 23457 7676767 YP_002732202.1 CDS BMEA_A0466 NC_012441.1 453142 453402 R transglycosylase-associated protein complement(453142..453402) Brucella melitensis ATCC 23457 7676768 YP_002732203.1 CDS BMEA_A0467 NC_012441.1 453565 454116 D hypothetical protein 453565..454116 Brucella melitensis ATCC 23457 7676769 YP_002732204.1 CDS BMEA_A0468 NC_012441.1 454320 455192 D Pirin domain-containing protein 454320..455192 Brucella melitensis ATCC 23457 7676770 YP_002732205.1 CDS dxs NC_012441.1 455335 457266 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 455335..457266 Brucella melitensis ATCC 23457 7676771 YP_002732206.1 CDS BMEA_A0470 NC_012441.1 457272 458033 D hemolysin A 457272..458033 Brucella melitensis ATCC 23457 7676772 YP_002732207.1 CDS BMEA_A0471 NC_012441.1 458030 459277 D tRNA (Uracil-5-)-methyltransferase 458030..459277 Brucella melitensis ATCC 23457 7676773 YP_002732208.1 CDS BMEA_A0472 NC_012441.1 459429 460031 R hypothetical protein complement(459429..460031) Brucella melitensis ATCC 23457 7676774 YP_002732209.1 CDS BMEA_A0473 NC_012441.1 460161 460526 D hypothetical protein 460161..460526 Brucella melitensis ATCC 23457 7676775 YP_002732210.1 CDS BMEA_A0474 NC_012441.1 460713 461927 D peptidoglycan-binding LysM 460713..461927 Brucella melitensis ATCC 23457 7676776 YP_002732211.1 CDS BMEA_A0475 NC_012441.1 462130 464016 D ABC transporter 462130..464016 Brucella melitensis ATCC 23457 7676777 YP_002732212.1 CDS BMEA_A0476 NC_012441.1 464121 464819 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 464121..464819 Brucella melitensis ATCC 23457 7676778 YP_002732213.1 CDS pssA NC_012441.1 464824 465660 D CDP-diacylglycerol--serine O-phosphatidyltransferase 464824..465660 Brucella melitensis ATCC 23457 7676779 YP_002732214.1 CDS BMEA_A0479 NC_012441.1 465745 466485 R short-chain dehydrogenase/reductase SDR complement(465745..466485) Brucella melitensis ATCC 23457 7676780 YP_002732215.1 CDS purF NC_012441.1 466554 468011 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(466554..468011) Brucella melitensis ATCC 23457 7676781 YP_002732216.1 CDS BMEA_A0481 NC_012441.1 468033 468230 D hypothetical protein 468033..468230 Brucella melitensis ATCC 23457 7676782 YP_002732217.1 CDS BMEA_A0482 NC_012441.1 468326 468904 R colicin V production protein complement(468326..468904) Brucella melitensis ATCC 23457 7676783 YP_002732218.1 CDS radA NC_012441.1 469030 470433 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(469030..470433) Brucella melitensis ATCC 23457 7676784 YP_002732219.1 CDS dnaB NC_012441.1 470461 471966 R unwinds double stranded DNA; replicative DNA helicase complement(470461..471966) Brucella melitensis ATCC 23457 7676785 YP_002732220.1 CDS BMEA_A0485 NC_012441.1 472165 473445 R cyclopropane-fatty-acyl-phospholipid synthase complement(472165..473445) Brucella melitensis ATCC 23457 7676786 YP_002732221.1 CDS rplI NC_012441.1 473819 474388 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(473819..474388) Brucella melitensis ATCC 23457 7676787 YP_002732222.1 CDS BMEA_A0487 NC_012441.1 474418 475389 R hypothetical protein complement(474418..475389) Brucella melitensis ATCC 23457 7676788 YP_002732223.1 CDS rpsR NC_012441.1 475540 475788 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(475540..475788) Brucella melitensis ATCC 23457 7676789 YP_002732224.1 CDS rpsF NC_012441.1 475791 476237 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(475791..476237) Brucella melitensis ATCC 23457 7676790 YP_002732225.1 CDS BMEA_A0491 NC_012441.1 476262 476621 R hypothetical protein complement(476262..476621) Brucella melitensis ATCC 23457 7676791 YP_002732226.1 CDS fabD NC_012441.1 476643 477587 D malonyl CoA-acyl carrier protein transacylase 476643..477587 Brucella melitensis ATCC 23457 7676792 YP_002732227.1 CDS fabG NC_012441.1 477657 478394 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 477657..478394 Brucella melitensis ATCC 23457 7676793 YP_002732228.1 CDS BMEA_A0494 NC_012441.1 478596 478967 R acyl carrier protein complement(478596..478967) Brucella melitensis ATCC 23457 7676794 YP_002732229.1 CDS acpP NC_012441.1 478668 478904 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 478668..478904 Brucella melitensis ATCC 23457 7676795 YP_002732230.1 CDS BMEA_A0496 NC_012441.1 478908 479171 D hypothetical protein 478908..479171 Brucella melitensis ATCC 23457 7676796 YP_002732231.1 CDS fabF NC_012441.1 479228 480490 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 479228..480490 Brucella melitensis ATCC 23457 7676797 YP_002732232.1 CDS BMEA_A0498 NC_012441.1 480715 481953 D hypothetical protein 480715..481953 Brucella melitensis ATCC 23457 7676798 YP_002732233.1 CDS gmk NC_012441.1 483045 483707 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 483045..483707 Brucella melitensis ATCC 23457 7676800 YP_002732234.1 CDS BMEA_A0501 NC_012441.1 483734 485146 R peptidase U62 complement(483734..485146) Brucella melitensis ATCC 23457 7676801 YP_002732235.1 CDS BMEA_A0502 NC_012441.1 485287 485913 R invasion associated locus B family protein complement(485287..485913) Brucella melitensis ATCC 23457 7676802 YP_002732236.1 CDS coxB NC_012441.1 486347 487201 D cytochrome c oxidase subunit II 486347..487201 Brucella melitensis ATCC 23457 7676803 YP_002732237.1 CDS ctaD NC_012441.1 487339 488997 D cytochrome c oxidase subunit I 487339..488997 Brucella melitensis ATCC 23457 7676804 YP_002732238.1 CDS cyoE NC_012441.1 489225 490172 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 489225..490172 Brucella melitensis ATCC 23457 7676805 YP_002732239.1 CDS BMEA_A0506 NC_012441.1 490172 490357 D hypothetical protein 490172..490357 Brucella melitensis ATCC 23457 7676806 YP_002732240.1 CDS BMEA_A0507 NC_012441.1 490377 490982 D involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 490377..490982 Brucella melitensis ATCC 23457 7676807 YP_002732241.1 CDS BMEA_A0508 NC_012441.1 491191 492069 D cytochrome c oxidase subunit 3 491191..492069 Brucella melitensis ATCC 23457 7676808 YP_002732242.1 CDS BMEA_A0509 NC_012441.1 492183 492566 D hypothetical protein 492183..492566 Brucella melitensis ATCC 23457 7676809 YP_002732243.1 CDS BMEA_A0510 NC_012441.1 492563 493312 D surfeit locus protein 1 492563..493312 Brucella melitensis ATCC 23457 7676810 YP_002732244.1 CDS ispH NC_012441.1 493343 494461 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 493343..494461 Brucella melitensis ATCC 23457 7676811 YP_002732245.1 CDS thrB NC_012441.1 494467 495447 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 494467..495447 Brucella melitensis ATCC 23457 7676812 YP_002732246.1 CDS BMEA_A0513 NC_012441.1 495444 495908 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 495444..495908 Brucella melitensis ATCC 23457 7676813 YP_002732247.1 CDS BMEA_A0514 NC_012441.1 495938 496423 R redoxin domain-containing protein complement(495938..496423) Brucella melitensis ATCC 23457 7676814 YP_002732248.1 CDS BMEA_A0515 NC_012441.1 496603 497403 R hypothetical protein complement(496603..497403) Brucella melitensis ATCC 23457 7676815 YP_002732249.1 CDS BMEA_A0516 NC_012441.1 497538 498140 D hypothetical protein 497538..498140 Brucella melitensis ATCC 23457 7676816 YP_002732250.1 CDS BMEA_A0517 NC_012441.1 498246 501140 R diguanylate cyclase complement(498246..501140) Brucella melitensis ATCC 23457 7676817 YP_002732251.1 CDS BMEA_A0518 NC_012441.1 501137 501757 R N-acetyltransferase GCN5 complement(501137..501757) Brucella melitensis ATCC 23457 7676818 YP_002732252.1 CDS BMEA_A0519 NC_012441.1 501928 503220 R processing protease complement(501928..503220) Brucella melitensis ATCC 23457 7676819 YP_002732253.1 CDS thrC NC_012441.1 503274 504665 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(503274..504665) Brucella melitensis ATCC 23457 7676820 YP_002732254.1 CDS BMEA_A0521 NC_012441.1 505026 505604 D lipoprotein 505026..505604 Brucella melitensis ATCC 23457 7676821 YP_002732255.1 CDS BMEA_A0522 NC_012441.1 505918 507552 D hypothetical protein 505918..507552 Brucella melitensis ATCC 23457 7676822 YP_002732256.1 CDS BMEA_A0524 NC_012441.1 507681 507866 D hypothetical protein 507681..507866 Brucella melitensis ATCC 23457 7676823 YP_002732257.1 CDS BMEA_A0525 NC_012441.1 507908 508594 R HAD-superfamily hydrolase complement(507908..508594) Brucella melitensis ATCC 23457 7676824 YP_002732258.1 CDS BMEA_A0526 NC_012441.1 508742 510280 R chloride channel core protein complement(508742..510280) Brucella melitensis ATCC 23457 7676825 YP_002732259.1 CDS BMEA_A0527 NC_012441.1 510259 510399 R hypothetical protein complement(510259..510399) Brucella melitensis ATCC 23457 7676826 YP_002732260.1 CDS BMEA_A0528 NC_012441.1 510593 511726 D modification methylase HinfI 510593..511726 Brucella melitensis ATCC 23457 7676827 YP_002732261.1 CDS BMEA_A0529 NC_012441.1 511809 512426 R HAD-superfamily hydrolase complement(511809..512426) Brucella melitensis ATCC 23457 7676828 YP_002732262.1 CDS mutY NC_012441.1 512423 513499 R A/G-specific adenine glycosylase complement(512423..513499) Brucella melitensis ATCC 23457 7676829 YP_002732263.1 CDS BMEA_A0531 NC_012441.1 513773 514300 D hypothetical protein 513773..514300 Brucella melitensis ATCC 23457 7676830 YP_002732264.1 CDS BMEA_A0532 NC_012441.1 514318 514491 D hypothetical protein 514318..514491 Brucella melitensis ATCC 23457 7676831 YP_002732265.1 CDS BMEA_A0533 NC_012441.1 514538 515191 D DSBA oxidoreductase 514538..515191 Brucella melitensis ATCC 23457 7676832 YP_002732266.1 CDS smc NC_012441.1 515270 518728 D chromosome segregation protein SMC 515270..518728 Brucella melitensis ATCC 23457 7676833 YP_002732267.1 CDS BMEA_A0535 NC_012441.1 518751 519644 D cation diffusion facilitator family transporter 518751..519644 Brucella melitensis ATCC 23457 7676834 YP_002732268.1 CDS BMEA_A0536 NC_012441.1 519754 520119 R hypothetical protein complement(519754..520119) Brucella melitensis ATCC 23457 7676835 YP_002732269.1 CDS ppdK NC_012441.1 520359 523022 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 520359..523022 Brucella melitensis ATCC 23457 7676836 YP_002732270.1 CDS BMEA_A0538 NC_012441.1 523236 524054 D polysaccharide deacetylase 523236..524054 Brucella melitensis ATCC 23457 7676837 YP_002732271.1 CDS BMEA_A0539 NC_012441.1 524257 524403 R hypothetical protein complement(524257..524403) Brucella melitensis ATCC 23457 7676838 YP_002732272.1 CDS BMEA_A0540 NC_012441.1 525015 525803 D hypothetical protein 525015..525803 Brucella melitensis ATCC 23457 7676839 YP_002732273.1 CDS BMEA_A0541 NC_012441.1 525804 526709 R beta-lactamase domain-containing protein complement(525804..526709) Brucella melitensis ATCC 23457 7676840 YP_002732274.1 CDS BMEA_A0542 NC_012441.1 526910 527509 D protein BioY 526910..527509 Brucella melitensis ATCC 23457 7676841 YP_002732275.1 CDS BMEA_A0543 NC_012441.1 527645 528154 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 527645..528154 Brucella melitensis ATCC 23457 7676842 YP_002732276.1 CDS pucM NC_012441.1 528166 528522 D hydroxyisourate hydrolase 528166..528522 Brucella melitensis ATCC 23457 7676843 YP_002732277.1 CDS BMEA_A0545 NC_012441.1 528593 529429 D hypothetical protein 528593..529429 Brucella melitensis ATCC 23457 7676844 YP_002732278.1 CDS BMEA_A0546 NC_012441.1 529966 531834 D polysaccharide biosynthesis protein CapD 529966..531834 Brucella melitensis ATCC 23457 7676845 YP_002732279.1 CDS BMEA_A0547 NC_012441.1 531821 532828 R family 4 glycosyl transferase complement(531821..532828) Brucella melitensis ATCC 23457 7676846 YP_002732280.1 CDS BMEA_A0549 NC_012441.1 533487 534305 D transposase and inactivated derivatives-like protein 533487..534305 Brucella melitensis ATCC 23457 7676848 YP_002732281.1 CDS BMEA_A0550 NC_012441.1 534037 534624 D insertion sequence transposase protein 534037..534624 Brucella melitensis ATCC 23457 7676849 YP_002732282.1 CDS BMEA_A0551 NC_012441.1 534681 534980 D insertion sequence transposase protein 534681..534980 Brucella melitensis ATCC 23457 7678309 YP_002732283.1 CDS BMEA_A0552 NC_012441.1 535037 535267 D transposase 535037..535267 Brucella melitensis ATCC 23457 7678310 YP_002732284.1 CDS BMEA_A0553 NC_012441.1 535518 535643 D transposase IS3/IS911 family protein 535518..535643 Brucella melitensis ATCC 23457 7678311 YP_002732285.1 CDS BMEA_A0554 NC_012441.1 535637 536359 D Is511 transposase orfB 535637..536359 Brucella melitensis ATCC 23457 7678312 YP_002732286.1 CDS BMEA_A0555 NC_012441.1 536695 537474 R bifunctional polymyxin resistance protein ArnA complement(536695..537474) Brucella melitensis ATCC 23457 7678313 YP_002732287.1 CDS BMEA_A0556 NC_012441.1 537501 538355 R WbcT protein complement(537501..538355) Brucella melitensis ATCC 23457 7678314 YP_002732288.1 CDS BMEA_A0557 NC_012441.1 538352 539110 R O-antigen export system ATP-binding protein rfbB complement(538352..539110) Brucella melitensis ATCC 23457 7678315 YP_002732289.1 CDS BMEA_A0558 NC_012441.1 539107 539889 R O-antigen export system permease rfbD complement(539107..539889) Brucella melitensis ATCC 23457 7678316 YP_002732290.1 CDS BMEA_A0559 NC_012441.1 539904 541007 R L-glutamine:2-deoxy-scyllo-inosose aminotransferase complement(539904..541007) Brucella melitensis ATCC 23457 7678317 YP_002732291.1 CDS gmd NC_012441.1 541015 542103 R GDP-mannose 4,6-dehydratase complement(541015..542103) Brucella melitensis ATCC 23457 7678318 YP_002732292.1 CDS BMEA_A0561 NC_012441.1 542741 543049 D ISBm1 transposase orfA 542741..543049 Brucella melitensis ATCC 23457 7678319 YP_002732293.1 CDS BMEA_A0562 NC_012441.1 542968 543342 D transposase and inactivated derivatives-like protein 542968..543342 Brucella melitensis ATCC 23457 7678320 YP_002732294.1 CDS BMEA_A0564 NC_012441.1 544235 544567 D transposase 544235..544567 Brucella melitensis ATCC 23457 7678322 YP_002732295.1 CDS BMEA_A0565 NC_012441.1 544993 545232 D transposase and inactivated derivatives-like protein 544993..545232 Brucella melitensis ATCC 23457 7678323 YP_002732296.1 CDS BMEA_A0566 NC_012441.1 545363 546481 D mannosyltransferase 545363..546481 Brucella melitensis ATCC 23457 7678324 YP_002732297.1 CDS BMEA_A0567 NC_012441.1 546539 546907 D transposase orfA IS5 family protein 546539..546907 Brucella melitensis ATCC 23457 7678325 YP_002732298.1 CDS BMEA_A0568 NC_012441.1 547003 547344 D transposase 547003..547344 Brucella melitensis ATCC 23457 7678326 YP_002732299.1 CDS BMEA_A0570 NC_012441.1 547808 547945 R Integrase, catalytic domain-containing protein complement(547808..547945) Brucella melitensis ATCC 23457 7678328 YP_002732300.1 CDS BMEA_A0571 NC_012441.1 548152 548580 D ISBm1 transposase orfA 548152..548580 Brucella melitensis ATCC 23457 7678329 YP_002732301.1 CDS BMEA_A0572 NC_012441.1 548499 548915 D transposase and inactivated derivatives-like protein 548499..548915 Brucella melitensis ATCC 23457 7678330 YP_002732302.1 CDS BMEA_A0573 NC_012441.1 549275 549574 D hypothetical protein 549275..549574 Brucella melitensis ATCC 23457 7678331 YP_002732303.1 CDS BMEA_A0574 NC_012441.1 549806 551095 D phosphomannomutase 549806..551095 Brucella melitensis ATCC 23457 7678332 YP_002732304.1 CDS BMEA_A0575 NC_012441.1 551166 552590 D mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 551166..552590 Brucella melitensis ATCC 23457 7678333 YP_002732305.1 CDS BMEA_A0576 NC_012441.1 552623 553795 D phosphomannose isomerase 552623..553795 Brucella melitensis ATCC 23457 7678334 YP_002732306.1 CDS BMEA_A0577 NC_012441.1 553878 554987 D glycosyltransferase protein 553878..554987 Brucella melitensis ATCC 23457 7678335 YP_002732307.1 CDS BMEA_A0578 NC_012441.1 555468 555647 R hypothetical protein complement(555468..555647) Brucella melitensis ATCC 23457 7678336 YP_002732308.1 CDS BMEA_A0580 NC_012441.1 557233 558234 D monosaccharide-transporting ATPase 557233..558234 Brucella melitensis ATCC 23457 7678338 YP_002732309.1 CDS BMEA_A0582 NC_012441.1 558313 559275 D hypothetical protein 558313..559275 Brucella melitensis ATCC 23457 7678339 YP_002732310.1 CDS BMEA_A0583 NC_012441.1 559333 560385 D hypothetical protein 559333..560385 Brucella melitensis ATCC 23457 7678340 YP_002732311.1 CDS BMEA_A0584 NC_012441.1 560393 561565 D oxidoreductase domain-containing protein 560393..561565 Brucella melitensis ATCC 23457 7678341 YP_002732312.1 CDS xylA NC_012441.1 561607 562914 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(561607..562914) Brucella melitensis ATCC 23457 7678342 YP_002732313.1 CDS xylB NC_012441.1 562961 564412 R xylulokinase complement(562961..564412) Brucella melitensis ATCC 23457 7678343 YP_002732314.1 CDS BMEA_A0587 NC_012441.1 564445 565476 R HTH-type transcriptional regulator DegA complement(564445..565476) Brucella melitensis ATCC 23457 7678344 YP_002732315.1 CDS betB NC_012441.1 567272 568735 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(567272..568735) Brucella melitensis ATCC 23457 7678346 YP_002732316.1 CDS betI NC_012441.1 570572 571168 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(570572..571168) Brucella melitensis ATCC 23457 7678348 YP_002732317.1 CDS BMEA_A0592 NC_012441.1 571359 572381 D L-asparaginase II protein 571359..572381 Brucella melitensis ATCC 23457 7678349 YP_002732318.1 CDS BMEA_A0593 NC_012441.1 572426 572896 D Transcription elongation factor greA 572426..572896 Brucella melitensis ATCC 23457 7678350 YP_002732319.1 CDS BMEA_A0594 NC_012441.1 572893 573282 R death-on-curing family protein complement(572893..573282) Brucella melitensis ATCC 23457 7678351 YP_002732320.1 CDS BMEA_A0595 NC_012441.1 573279 573509 R addiction module antidote complement(573279..573509) Brucella melitensis ATCC 23457 7678352 YP_002732321.1 CDS BMEA_A0596 NC_012441.1 573570 574562 R Mg2 transporter protein CorA family protein complement(573570..574562) Brucella melitensis ATCC 23457 7678353 YP_002732322.1 CDS BMEA_A0597 NC_012441.1 574718 575395 D GntR family transcriptional regulator 574718..575395 Brucella melitensis ATCC 23457 7678354 YP_002732323.1 CDS BMEA_A0598 NC_012441.1 575392 576690 D major facilitator superfamily protein 575392..576690 Brucella melitensis ATCC 23457 7678355 YP_002732324.1 CDS BMEA_A0599 NC_012441.1 576747 577109 R hypothetical protein complement(576747..577109) Brucella melitensis ATCC 23457 7678356 YP_002732325.1 CDS BMEA_A0600 NC_012441.1 577445 578956 D hypothetical protein 577445..578956 Brucella melitensis ATCC 23457 7678357 YP_002732326.1 CDS BMEA_A0601 NC_012441.1 578998 579096 D hypothetical protein 578998..579096 Brucella melitensis ATCC 23457 7678358 YP_002732327.1 CDS BMEA_A0602 NC_012441.1 579154 579870 R ErfK/YbiS/YcfS/YnhG family protein complement(579154..579870) Brucella melitensis ATCC 23457 7678359 YP_002732328.1 CDS BMEA_A0604 NC_012441.1 581048 581647 D superoxide dismutase 581048..581647 Brucella melitensis ATCC 23457 7678361 YP_002732329.1 CDS BMEA_A0606 NC_012441.1 581819 582205 R hypothetical protein complement(581819..582205) Brucella melitensis ATCC 23457 7678362 YP_002732330.1 CDS BMEA_A0607 NC_012441.1 582272 584380 R protease 2 complement(582272..584380) Brucella melitensis ATCC 23457 7678363 YP_002732331.1 CDS BMEA_A0608 NC_012441.1 584804 584965 D hypothetical protein 584804..584965 Brucella melitensis ATCC 23457 7678364 YP_002732332.1 CDS BMEA_A0609 NC_012441.1 584953 585381 D transcriptional regulator RosAr 584953..585381 Brucella melitensis ATCC 23457 7678365 YP_002732333.1 CDS BMEA_A0610 NC_012441.1 585589 585900 R hypothetical protein complement(585589..585900) Brucella melitensis ATCC 23457 7678366 YP_002732334.1 CDS BMEA_A0611 NC_012441.1 586082 586537 D hypothetical protein 586082..586537 Brucella melitensis ATCC 23457 7678367 YP_002732335.1 CDS BMEA_A0612 NC_012441.1 586534 587307 D hypothetical protein 586534..587307 Brucella melitensis ATCC 23457 7678368 YP_002732336.1 CDS BMEA_A0613 NC_012441.1 587420 588757 D catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 587420..588757 Brucella melitensis ATCC 23457 7678369 YP_002732337.1 CDS BMEA_A0614 NC_012441.1 588798 589223 R hypothetical protein complement(588798..589223) Brucella melitensis ATCC 23457 7678370 YP_002732338.1 CDS BMEA_A0615 NC_012441.1 589303 589752 R hypothetical protein complement(589303..589752) Brucella melitensis ATCC 23457 7678371 YP_002732339.1 CDS BMEA_A0616 NC_012441.1 590043 591872 D integral membrane sensor signal transduction histidine kinase 590043..591872 Brucella melitensis ATCC 23457 7678372 YP_002732340.1 CDS BMEA_A0617 NC_012441.1 591799 592815 D peptidoglycan-binding domain 1 protein 591799..592815 Brucella melitensis ATCC 23457 7678373 YP_002732341.1 CDS BMEA_A0618 NC_012441.1 592829 593176 D hypothetical protein 592829..593176 Brucella melitensis ATCC 23457 7678374 YP_002732342.1 CDS BMEA_A0619 NC_012441.1 593187 594245 R hypothetical protein complement(593187..594245) Brucella melitensis ATCC 23457 7678375 YP_002732343.1 CDS BMEA_A0620 NC_012441.1 594443 594985 R hypothetical protein complement(594443..594985) Brucella melitensis ATCC 23457 7678376 YP_002732344.1 CDS BMEA_A0621 NC_012441.1 594978 595589 R hypothetical protein complement(594978..595589) Brucella melitensis ATCC 23457 7678377 YP_002732345.1 CDS BMEA_A0622 NC_012441.1 595596 597752 R 1A family penicillin-binding protein complement(595596..597752) Brucella melitensis ATCC 23457 7678378 YP_002732346.1 CDS BMEA_A0624 NC_012441.1 598585 599820 D hypothetical protein 598585..599820 Brucella melitensis ATCC 23457 7678379 YP_002732347.1 CDS BMEA_A0625 NC_012441.1 599852 601045 D phage portal protein 599852..601045 Brucella melitensis ATCC 23457 7678380 YP_002732348.1 CDS BMEA_A0626 NC_012441.1 601042 601419 D hypothetical protein 601042..601419 Brucella melitensis ATCC 23457 7678381 YP_002732349.1 CDS BMEA_A0628 NC_012441.1 602097 603371 D phage major capsid protein 602097..603371 Brucella melitensis ATCC 23457 7676284 YP_002732350.1 CDS BMEA_A0629 NC_012441.1 603536 604102 D hypothetical protein 603536..604102 Brucella melitensis ATCC 23457 7676285 YP_002732351.1 CDS BMEA_A0630 NC_012441.1 604099 604437 D phage head-tail adaptor 604099..604437 Brucella melitensis ATCC 23457 7676286 YP_002732352.1 CDS BMEA_A0631 NC_012441.1 604559 604966 D hypothetical protein 604559..604966 Brucella melitensis ATCC 23457 7676287 YP_002732353.1 CDS BMEA_A0632 NC_012441.1 605007 605420 D phage major tail protein 605007..605420 Brucella melitensis ATCC 23457 7676288 YP_002732354.1 CDS BMEA_A0633 NC_012441.1 605417 605758 D hypothetical protein 605417..605758 Brucella melitensis ATCC 23457 7676289 YP_002732355.1 CDS BMEA_A0634 NC_012441.1 605802 605972 D hypothetical protein 605802..605972 Brucella melitensis ATCC 23457 7676290 YP_002732356.1 CDS BMEA_A0635 NC_012441.1 605977 606522 D hypothetical protein 605977..606522 Brucella melitensis ATCC 23457 7676291 YP_002732357.1 CDS BMEA_A0636 NC_012441.1 606525 607157 D hypothetical protein 606525..607157 Brucella melitensis ATCC 23457 7676292 YP_002732358.1 CDS BMEA_A0637 NC_012441.1 607154 608029 D hypothetical protein 607154..608029 Brucella melitensis ATCC 23457 7676293 YP_002732359.1 CDS BMEA_A0638 NC_012441.1 608026 608460 D phage cell wall peptidase NlpC/P60 family protein 608026..608460 Brucella melitensis ATCC 23457 7676294 YP_002732360.1 CDS BMEA_A0640 NC_012441.1 612390 612596 D hypothetical protein 612390..612596 Brucella melitensis ATCC 23457 7676296 YP_002732361.1 CDS BMEA_A0641 NC_012441.1 612758 613054 D hypothetical protein 612758..613054 Brucella melitensis ATCC 23457 7676297 YP_002732362.1 CDS BMEA_A0642 NC_012441.1 613133 613822 D winged helix family two component transcriptional regulator 613133..613822 Brucella melitensis ATCC 23457 7676298 YP_002732363.1 CDS BMEA_A0643 NC_012441.1 613972 615207 D histidine kinase 613972..615207 Brucella melitensis ATCC 23457 7676299 YP_002732364.1 CDS BMEA_A0644 NC_012441.1 615268 615753 D outer membrane lipoprotein-related protein 615268..615753 Brucella melitensis ATCC 23457 7676300 YP_002732365.1 CDS ccmI NC_012441.1 615854 616993 D cytochrome c-type biogenesis protein CcmI 615854..616993 Brucella melitensis ATCC 23457 7676301 YP_002732366.1 CDS BMEA_A0646 NC_012441.1 616990 617487 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 616990..617487 Brucella melitensis ATCC 23457 7676302 YP_002732367.1 CDS ccmF NC_012441.1 617507 619498 D cytochrome c-type biogenesis protein CcmF 617507..619498 Brucella melitensis ATCC 23457 7676303 YP_002732368.1 CDS BMEA_A0648 NC_012441.1 619495 619971 D cytochrome c-type biogenesis protein ccl2 619495..619971 Brucella melitensis ATCC 23457 7676304 YP_002732369.1 CDS degP NC_012441.1 620113 621654 D protease Do 620113..621654 Brucella melitensis ATCC 23457 7676305 YP_002732370.1 CDS BMEA_A0650 NC_012441.1 621748 622455 D transcriptional activator protein copR 621748..622455 Brucella melitensis ATCC 23457 7676306 YP_002732371.1 CDS BMEA_A0651 NC_012441.1 622455 623858 D integral membrane sensor signal transduction histidine kinase 622455..623858 Brucella melitensis ATCC 23457 7676307 YP_002732372.1 CDS BMEA_A0652 NC_012441.1 623981 626932 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 623981..626932 Brucella melitensis ATCC 23457 7676308 YP_002732373.1 CDS BMEA_A0653 NC_012441.1 626977 629088 R glycosyltransferase 25 family protein complement(626977..629088) Brucella melitensis ATCC 23457 7676309 YP_002732374.1 CDS BMEA_A0654 NC_012441.1 629359 631710 R PAS domain S-box-containing protein complement(629359..631710) Brucella melitensis ATCC 23457 7676310 YP_002732375.1 CDS pepN NC_012441.1 632101 634752 R aminopeptidase N complement(632101..634752) Brucella melitensis ATCC 23457 7676311 YP_002732376.1 CDS BMEA_A0656 NC_012441.1 634921 635937 D hypothetical protein 634921..635937 Brucella melitensis ATCC 23457 7676312 YP_002732377.1 CDS BMEA_A0657 NC_012441.1 635942 637198 R major facilitator superfamily protein complement(635942..637198) Brucella melitensis ATCC 23457 7676313 YP_002732378.1 CDS BMEA_A0658 NC_012441.1 637360 638232 R uracil-DNA glycosylase complement(637360..638232) Brucella melitensis ATCC 23457 7676314 YP_002732379.1 CDS BMEA_A0659 NC_012441.1 638621 640312 D electron-transferring-flavoprotein dehydrogenase 638621..640312 Brucella melitensis ATCC 23457 7676315 YP_002732380.1 CDS BMEA_A0660 NC_012441.1 640428 641504 R hypothetical protein complement(640428..641504) Brucella melitensis ATCC 23457 7676316 YP_002732381.1 CDS amn NC_012441.1 641557 643059 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(641557..643059) Brucella melitensis ATCC 23457 7676317 YP_002732382.1 CDS BMEA_A0663 NC_012441.1 643112 643270 D hypothetical protein 643112..643270 Brucella melitensis ATCC 23457 7676318 YP_002732383.1 CDS BMEA_A0664 NC_012441.1 643267 643548 D hypothetical protein 643267..643548 Brucella melitensis ATCC 23457 7676319 YP_002732384.1 CDS BMEA_A0665 NC_012441.1 643626 644336 D glutathione S-transferase domain-containing protein 643626..644336 Brucella melitensis ATCC 23457 7676320 YP_002732385.1 CDS BMEA_A0666 NC_012441.1 644395 644742 R hypothetical protein complement(644395..644742) Brucella melitensis ATCC 23457 7676321 YP_002732386.1 CDS BMEA_A0667 NC_012441.1 644739 645029 R hypothetical protein complement(644739..645029) Brucella melitensis ATCC 23457 7676322 YP_002732387.1 CDS BMEA_A0668 NC_012441.1 645248 645505 D hypothetical protein 645248..645505 Brucella melitensis ATCC 23457 7676323 YP_002732388.1 CDS BMEA_A0669 NC_012441.1 645565 646338 R hypothetical protein complement(645565..646338) Brucella melitensis ATCC 23457 7676324 YP_002732389.1 CDS BMEA_A0670 NC_012441.1 646601 646696 D hypothetical protein 646601..646696 Brucella melitensis ATCC 23457 7676325 YP_002732390.1 CDS BMEA_A0671 NC_012441.1 646990 647640 D hypothetical protein 646990..647640 Brucella melitensis ATCC 23457 7676326 YP_002732391.1 CDS BMEA_A0672 NC_012441.1 647685 648059 R oxidoreductase Gfo/Idh/MocA family protein complement(647685..648059) Brucella melitensis ATCC 23457 7676327 YP_002732392.1 CDS BMEA_A0673 NC_012441.1 648077 649210 R catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; histidinol-phosphate aminotransferase complement(648077..649210) Brucella melitensis ATCC 23457 7676328 YP_002732393.1 CDS BMEA_A0674 NC_012441.1 649573 650499 R tyrosine recombinase XerC complement(649573..650499) Brucella melitensis ATCC 23457 7676329 YP_002732394.1 CDS BMEA_A0675 NC_012441.1 650774 651877 R outer membrane protein IIIA precursor complement(650774..651877) Brucella melitensis ATCC 23457 7676330 YP_002732395.1 CDS BMEA_A0677 NC_012441.1 652678 653805 D outer membrane protein IIIA precursor 652678..653805 Brucella melitensis ATCC 23457 7676332 YP_002732396.1 CDS BMEA_A0678 NC_012441.1 653949 654590 D hypothetical protein 653949..654590 Brucella melitensis ATCC 23457 7676333 YP_002732397.1 CDS BMEA_A0679 NC_012441.1 654646 654828 D hypothetical protein 654646..654828 Brucella melitensis ATCC 23457 7676334 YP_002732398.1 CDS BMEA_A0680 NC_012441.1 654889 655563 D 50S ribosomal protein L21 654889..655563 Brucella melitensis ATCC 23457 7676335 YP_002732399.1 CDS BMEA_A0681 NC_012441.1 655626 657683 R lytic transglycosylase complement(655626..657683) Brucella melitensis ATCC 23457 7676336 YP_002732400.1 CDS dapA NC_012441.1 658159 659040 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 658159..659040 Brucella melitensis ATCC 23457 7676337 YP_002732401.1 CDS smpB NC_012441.1 659131 659607 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 659131..659607 Brucella melitensis ATCC 23457 7676338 YP_002732402.1 CDS BMEA_A0685 NC_012441.1 659744 660415 R uracil-DNA glycosylase superfamily protein complement(659744..660415) Brucella melitensis ATCC 23457 7676339 YP_002732403.1 CDS BMEA_A0686 NC_012441.1 660446 661021 R hypothetical protein complement(660446..661021) Brucella melitensis ATCC 23457 7676340 YP_002732404.1 CDS BMEA_A0687 NC_012441.1 661221 661376 R hypothetical protein complement(661221..661376) Brucella melitensis ATCC 23457 7676341 YP_002732405.1 CDS rpoZ NC_012441.1 661418 661819 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 661418..661819 Brucella melitensis ATCC 23457 7676342 YP_002732406.1 CDS BMEA_A0689 NC_012441.1 662060 664312 D RelA/SpoT family protein 662060..664312 Brucella melitensis ATCC 23457 7676343 YP_002732407.1 CDS pyrE NC_012441.1 664320 664898 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 664320..664898 Brucella melitensis ATCC 23457 7676344 YP_002732408.1 CDS BMEA_A0691 NC_012441.1 665058 665813 D transcriptional activator protein fnrA 665058..665813 Brucella melitensis ATCC 23457 7676345 YP_002732409.1 CDS hemN NC_012441.1 666194 667528 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 666194..667528 Brucella melitensis ATCC 23457 7676346 YP_002732410.1 CDS BMEA_A0693 NC_012441.1 667712 668923 R major facilitator superfamily protein complement(667712..668923) Brucella melitensis ATCC 23457 7676347 YP_002732411.1 CDS BMEA_A0694 NC_012441.1 669175 670014 D AraC family transcriptional regulator 669175..670014 Brucella melitensis ATCC 23457 7676348 YP_002732412.1 CDS BMEA_A0695 NC_012441.1 670064 670639 D hypothetical protein 670064..670639 Brucella melitensis ATCC 23457 7676349 YP_002732413.1 CDS acpS NC_012441.1 670636 671040 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 670636..671040 Brucella melitensis ATCC 23457 7676350 YP_002732414.1 CDS lepB NC_012441.1 671151 671933 D signal peptidase I 671151..671933 Brucella melitensis ATCC 23457 7676351 YP_002732415.1 CDS rnc NC_012441.1 671902 672639 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 671902..672639 Brucella melitensis ATCC 23457 7676352 YP_002732416.1 CDS BMEA_A0699 NC_012441.1 672682 672780 D hypothetical protein 672682..672780 Brucella melitensis ATCC 23457 7676353 YP_002732417.1 CDS era NC_012441.1 672784 673719 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 672784..673719 Brucella melitensis ATCC 23457 7676354 YP_002732418.1 CDS recO NC_012441.1 673746 674489 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 673746..674489 Brucella melitensis ATCC 23457 7676355 YP_002732419.1 CDS BMEA_A0702 NC_012441.1 674467 674976 R hypothetical protein complement(674467..674976) Brucella melitensis ATCC 23457 7676356 YP_002732420.1 CDS BMEA_A0703 NC_012441.1 674973 675593 R hypothetical protein complement(674973..675593) Brucella melitensis ATCC 23457 7676357 YP_002732421.1 CDS ygfZ NC_012441.1 675593 676456 R folate-binding protein YgfZ complement(675593..676456) Brucella melitensis ATCC 23457 7676358 YP_002732422.1 CDS pyrC NC_012441.1 676542 677876 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 676542..677876 Brucella melitensis ATCC 23457 7676359 YP_002732423.1 CDS BMEA_A0706 NC_012441.1 677925 678689 R hypothetical protein complement(677925..678689) Brucella melitensis ATCC 23457 7676360 YP_002732424.1 CDS BMEA_A0707 NC_012441.1 678738 679004 R hypothetical protein complement(678738..679004) Brucella melitensis ATCC 23457 7676361 YP_002732425.1 CDS BMEA_A0708 NC_012441.1 679161 679544 R hypothetical protein complement(679161..679544) Brucella melitensis ATCC 23457 7676362 YP_002732426.1 CDS BMEA_A0709 NC_012441.1 679624 680067 R NUDIX hydrolase complement(679624..680067) Brucella melitensis ATCC 23457 7676363 YP_002732427.1 CDS BMEA_A0710 NC_012441.1 680153 680932 D hypothetical protein 680153..680932 Brucella melitensis ATCC 23457 7676364 YP_002732428.1 CDS BMEA_A0711 NC_012441.1 680987 681601 D amino-acid transporter yggA 680987..681601 Brucella melitensis ATCC 23457 7677394 YP_002732429.1 CDS BMEA_A0712 NC_012441.1 681578 681745 R hypothetical protein complement(681578..681745) Brucella melitensis ATCC 23457 7676850 YP_002732430.1 CDS BMEA_A0713 NC_012441.1 681750 681965 R hypothetical protein complement(681750..681965) Brucella melitensis ATCC 23457 7676851 YP_002732431.1 CDS cysS NC_012441.1 682112 683632 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 682112..683632 Brucella melitensis ATCC 23457 7676852 YP_002732432.1 CDS BMEA_A0715 NC_012441.1 683651 685264 D putative alpha-isopropylmalate/homocitrate synthase family transferase 683651..685264 Brucella melitensis ATCC 23457 7676853 YP_002732433.1 CDS rarD NC_012441.1 685515 686435 D RarD protein 685515..686435 Brucella melitensis ATCC 23457 7676854 YP_002732434.1 CDS BMEA_A0717 NC_012441.1 686568 688301 D peptidase M23B 686568..688301 Brucella melitensis ATCC 23457 7676855 YP_002732435.1 CDS ksgA NC_012441.1 688369 689199 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(688369..689199) Brucella melitensis ATCC 23457 7676856 YP_002732436.1 CDS pdxA NC_012441.1 689196 690227 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(689196..690227) Brucella melitensis ATCC 23457 7676857 YP_002732437.1 CDS BMEA_A0720 NC_012441.1 690292 691248 R chaperone SurA complement(690292..691248) Brucella melitensis ATCC 23457 7676858 YP_002732438.1 CDS BMEA_A0721 NC_012441.1 691576 693954 R LPS-assembly protein complement(691576..693954) Brucella melitensis ATCC 23457 7676859 YP_002732439.1 CDS BMEA_A0722 NC_012441.1 693975 695063 R YjgP/YjgQ family permease complement(693975..695063) Brucella melitensis ATCC 23457 7676860 YP_002732440.1 CDS BMEA_A0723 NC_012441.1 695060 696268 R YjgP/YjgQ family permease complement(695060..696268) Brucella melitensis ATCC 23457 7676861 YP_002732441.1 CDS BMEA_A0724 NC_012441.1 696441 696605 R hypothetical protein complement(696441..696605) Brucella melitensis ATCC 23457 7676862 YP_002732442.1 CDS BMEA_A0725 NC_012441.1 696678 698171 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 696678..698171 Brucella melitensis ATCC 23457 7676863 YP_002732443.1 CDS BMEA_A0726 NC_012441.1 698243 698692 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 698243..698692 Brucella melitensis ATCC 23457 7676864 YP_002732444.1 CDS BMEA_A0727 NC_012441.1 698692 699255 D hypothetical protein 698692..699255 Brucella melitensis ATCC 23457 7676865 YP_002732445.1 CDS BMEA_A0728 NC_012441.1 699315 701255 R ATP-binding protein complement(699315..701255) Brucella melitensis ATCC 23457 7676866 YP_002732446.1 CDS BMEA_A0729 NC_012441.1 701259 701771 R DinB family protein complement(701259..701771) Brucella melitensis ATCC 23457 7676867 YP_002732447.1 CDS BMEA_A0730 NC_012441.1 702000 702422 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 702000..702422 Brucella melitensis ATCC 23457 7676868 YP_002732448.1 CDS BMEA_A0731 NC_012441.1 702532 703335 R hypothetical protein complement(702532..703335) Brucella melitensis ATCC 23457 7676869 YP_002732449.1 CDS BMEA_A0732 NC_012441.1 703573 704064 R molybdopterin biosynthesis MoaE protein complement(703573..704064) Brucella melitensis ATCC 23457 7676870 YP_002732450.1 CDS moaD NC_012441.1 704066 704323 R molybdopterin converting factor subunit 1 complement(704066..704323) Brucella melitensis ATCC 23457 7676871 YP_002732451.1 CDS pgsA NC_012441.1 704328 704912 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(704328..704912) Brucella melitensis ATCC 23457 7676872 YP_002732452.1 CDS uvrC NC_012441.1 705031 707088 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(705031..707088) Brucella melitensis ATCC 23457 7676873 YP_002732453.1 CDS BMEA_A0736 NC_012441.1 707088 707843 R short chain dehydrogenase complement(707088..707843) Brucella melitensis ATCC 23457 7676874 YP_002732454.1 CDS BMEA_A0737 NC_012441.1 708048 708206 D hypothetical protein 708048..708206 Brucella melitensis ATCC 23457 7676875 YP_002732455.1 CDS BMEA_A0738 NC_012441.1 708245 708886 D OmpA-like transmembrane domain-containing protein 708245..708886 Brucella melitensis ATCC 23457 7676876 YP_002732456.1 CDS BMEA_A0739 NC_012441.1 708983 709582 R glutathione S-transferase domain-containing protein complement(708983..709582) Brucella melitensis ATCC 23457 7676877 YP_002732457.1 CDS BMEA_A0741 NC_012441.1 709637 710326 R ribonuclease complement(709637..710326) Brucella melitensis ATCC 23457 7676878 YP_002732458.1 CDS BMEA_A0742 NC_012441.1 710339 710809 R hypothetical protein complement(710339..710809) Brucella melitensis ATCC 23457 7676879 YP_002732459.1 CDS BMEA_A0743 NC_012441.1 710892 711764 R hypothetical protein complement(710892..711764) Brucella melitensis ATCC 23457 7676880 YP_002732460.1 CDS BMEA_A0744 NC_012441.1 711920 712765 D hypothetical protein 711920..712765 Brucella melitensis ATCC 23457 7676881 YP_002732461.1 CDS BMEA_A0745 NC_012441.1 712843 714969 D nitrate reductase 712843..714969 Brucella melitensis ATCC 23457 7676882 YP_002732462.1 CDS BMEA_A0746 NC_012441.1 715095 715619 R hypothetical protein complement(715095..715619) Brucella melitensis ATCC 23457 7676883 YP_002732463.1 CDS purN NC_012441.1 715795 716412 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(715795..716412) Brucella melitensis ATCC 23457 7676884 YP_002732464.1 CDS purM NC_012441.1 716409 717488 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(716409..717488) Brucella melitensis ATCC 23457 7676885 YP_002732465.1 CDS BMEA_A0749 NC_012441.1 717530 717709 R hypothetical protein complement(717530..717709) Brucella melitensis ATCC 23457 7676886 YP_002732466.1 CDS BMEA_A0750 NC_012441.1 717978 719126 D hypothetical protein 717978..719126 Brucella melitensis ATCC 23457 7676887 YP_002732467.1 CDS BMEA_A0751 NC_012441.1 719166 719861 D hypothetical protein 719166..719861 Brucella melitensis ATCC 23457 7676888 YP_002732468.1 CDS BMEA_A0752 NC_012441.1 719858 720727 D UDP-glucose 4-epimerase 719858..720727 Brucella melitensis ATCC 23457 7676889 YP_002732469.1 CDS BMEA_A0753 NC_012441.1 720724 721509 R hypothetical protein complement(720724..721509) Brucella melitensis ATCC 23457 7676890 YP_002732470.1 CDS BMEA_A0754 NC_012441.1 721582 722286 R oxidoreductase, short-chain dehydrogenase/reductase family protein complement(721582..722286) Brucella melitensis ATCC 23457 7676891 YP_002732471.1 CDS BMEA_A0755 NC_012441.1 722448 722663 R hypothetical protein complement(722448..722663) Brucella melitensis ATCC 23457 7676892 YP_002732472.1 CDS BMEA_A0756 NC_012441.1 722677 722832 D hypothetical protein 722677..722832 Brucella melitensis ATCC 23457 7676893 YP_002732473.1 CDS BMEA_A0759 NC_012441.1 725203 725508 D ETC complex I subunit protein 725203..725508 Brucella melitensis ATCC 23457 7676896 YP_002732474.1 CDS BMEA_A0761 NC_012441.1 726074 726664 D hypothetical protein 726074..726664 Brucella melitensis ATCC 23457 7676898 YP_002732475.1 CDS BMEA_A0762 NC_012441.1 726885 727496 R exonuclease complement(726885..727496) Brucella melitensis ATCC 23457 7676899 YP_002732476.1 CDS BMEA_A0763 NC_012441.1 727807 728139 D transposase 727807..728139 Brucella melitensis ATCC 23457 7676900 YP_002732477.1 CDS BMEA_A0764 NC_012441.1 728665 729210 R ATP synthase subunit beta complement(728665..729210) Brucella melitensis ATCC 23457 7676901 YP_002732478.1 CDS BMEA_A0765 NC_012441.1 729207 730742 R N-acetyltransferase GCN5 complement(729207..730742) Brucella melitensis ATCC 23457 7676902 YP_002732479.1 CDS BMEA_A0766 NC_012441.1 730717 731511 R helix-turn-helix domain-containing protein complement(730717..731511) Brucella melitensis ATCC 23457 7676903 YP_002732480.1 CDS BMEA_A0767 NC_012441.1 731536 731955 R hypothetical protein complement(731536..731955) Brucella melitensis ATCC 23457 7676904 YP_002732481.1 CDS BMEA_A0768 NC_012441.1 732335 733231 D hypothetical protein 732335..733231 Brucella melitensis ATCC 23457 7676905 YP_002732482.1 CDS BMEA_A0769 NC_012441.1 733231 735345 D integrase catalytic domain-containing protein 733231..735345 Brucella melitensis ATCC 23457 7676906 YP_002732483.1 CDS BMEA_A0772 NC_012441.1 738159 738356 R hypothetical protein complement(738159..738356) Brucella melitensis ATCC 23457 7676909 YP_002732484.1 CDS BMEA_A0773 NC_012441.1 738597 739904 D hypothetical protein 738597..739904 Brucella melitensis ATCC 23457 7676910 YP_002732485.1 CDS BMEA_A0774 NC_012441.1 740358 741731 D hypothetical protein 740358..741731 Brucella melitensis ATCC 23457 7676911 YP_002732486.1 CDS BMEA_A0775 NC_012441.1 741820 742698 D hypothetical protein 741820..742698 Brucella melitensis ATCC 23457 7676912 YP_002732487.1 CDS BMEA_A0776 NC_012441.1 743082 743594 R SH3 type 3 domain-containing protein complement(743082..743594) Brucella melitensis ATCC 23457 7676913 YP_002732488.1 CDS BMEA_A0777 NC_012441.1 743754 744002 R lipoprotein complement(743754..744002) Brucella melitensis ATCC 23457 7676914 YP_002732489.1 CDS BMEA_A0778 NC_012441.1 744105 744260 R hypothetical protein complement(744105..744260) Brucella melitensis ATCC 23457 7676915 YP_002732490.1 CDS metC NC_012441.1 744247 745416 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(744247..745416) Brucella melitensis ATCC 23457 7676916 YP_002732491.1 CDS BMEA_A0780 NC_012441.1 745627 746394 D bacitracin transport permease BcrC 745627..746394 Brucella melitensis ATCC 23457 7676917 YP_002732492.1 CDS BMEA_A0781 NC_012441.1 746849 747880 D lysine-arginine-ornithine-binding periplasmic protein 746849..747880 Brucella melitensis ATCC 23457 7676918 YP_002732493.1 CDS BMEA_A0782 NC_012441.1 747914 748141 D hypothetical protein 747914..748141 Brucella melitensis ATCC 23457 7676919 YP_002732494.1 CDS BMEA_A0783 NC_012441.1 748177 749370 D His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 748177..749370 Brucella melitensis ATCC 23457 7676920 YP_002732495.1 CDS BMEA_A0785 NC_012441.1 750544 751359 D glutamate/glutamine/aspartate/asparagine transport ATP-binding protein BztD 750544..751359 Brucella melitensis ATCC 23457 7676922 YP_002732496.1 CDS BMEA_A0786 NC_012441.1 751407 752612 R catalyzes the formation of catechol from salicylate; salicylate hydroxylase complement(751407..752612) Brucella melitensis ATCC 23457 7676923 YP_002732497.1 CDS BMEA_A0787 NC_012441.1 752642 752896 R hypothetical protein complement(752642..752896) Brucella melitensis ATCC 23457 7676924 YP_002732498.1 CDS BMEA_A0788 NC_012441.1 753182 755422 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 753182..755422 Brucella melitensis ATCC 23457 7676925 YP_002732499.1 CDS BMEA_A0789 NC_012441.1 755419 756957 D Ppx/GppA phosphatase 755419..756957 Brucella melitensis ATCC 23457 7676926 YP_002732500.1 CDS rnd NC_012441.1 757055 758212 R ribonuclease D complement(757055..758212) Brucella melitensis ATCC 23457 7676927 YP_002732501.1 CDS aspS NC_012441.1 758439 760226 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 758439..760226 Brucella melitensis ATCC 23457 7676928 YP_002732502.1 CDS BMEA_A0792 NC_012441.1 760267 761463 R hypothetical protein complement(760267..761463) Brucella melitensis ATCC 23457 7676929 YP_002732503.1 CDS BMEA_A0793 NC_012441.1 761518 761757 D hypothetical protein 761518..761757 Brucella melitensis ATCC 23457 7676930 YP_002732504.1 CDS parC NC_012441.1 761863 764175 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 761863..764175 Brucella melitensis ATCC 23457 7677883 YP_002732505.1 CDS BMEA_A0795 NC_012441.1 764354 765103 R Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase complement(764354..765103) Brucella melitensis ATCC 23457 7677884 YP_002732506.1 CDS BMEA_A0796 NC_012441.1 765224 765694 R RDD domain-containing protein complement(765224..765694) Brucella melitensis ATCC 23457 7677885 YP_002732507.1 CDS BMEA_A0797 NC_012441.1 765841 766878 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(765841..766878) Brucella melitensis ATCC 23457 7677886 YP_002732508.1 CDS BMEA_A0798 NC_012441.1 767046 768095 D catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 767046..768095 Brucella melitensis ATCC 23457 7677887 YP_002732509.1 CDS BMEA_A0799 NC_012441.1 768109 768543 D hypothetical protein 768109..768543 Brucella melitensis ATCC 23457 7677888 YP_002732510.1 CDS BMEA_A0800 NC_012441.1 768774 769373 D MarR family transcriptional regulator 768774..769373 Brucella melitensis ATCC 23457 7677889 YP_002732511.1 CDS BMEA_A0801 NC_012441.1 769460 769600 R hypothetical protein complement(769460..769600) Brucella melitensis ATCC 23457 7677890 YP_002732512.1 CDS BMEA_A0802 NC_012441.1 769735 771036 D peptidoglycan-binding domain 1 protein 769735..771036 Brucella melitensis ATCC 23457 7677891 YP_002732513.1 CDS BMEA_A0803 NC_012441.1 771129 771263 D hypothetical protein 771129..771263 Brucella melitensis ATCC 23457 7677892 YP_002732514.1 CDS BMEA_A0804 NC_012441.1 771267 772583 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 771267..772583 Brucella melitensis ATCC 23457 7677893 YP_002732515.1 CDS BMEA_A0805 NC_012441.1 772840 773316 D transcriptional regulator NrdR 772840..773316 Brucella melitensis ATCC 23457 7677894 YP_002732516.1 CDS ribD NC_012441.1 773318 774439 D Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; riboflavin biosynthesis protein RibD 773318..774439 Brucella melitensis ATCC 23457 7677895 YP_002732517.1 CDS ribE NC_012441.1 774439 775047 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 774439..775047 Brucella melitensis ATCC 23457 7677896 YP_002732518.1 CDS ribH NC_012441.1 775142 775603 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 775142..775603 Brucella melitensis ATCC 23457 7677897 YP_002732519.1 CDS nusB NC_012441.1 775609 776124 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 775609..776124 Brucella melitensis ATCC 23457 7677898 YP_002732520.1 CDS BMEA_A0810 NC_012441.1 776575 778731 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 776575..778731 Brucella melitensis ATCC 23457 7677899 YP_002732521.1 CDS BMEA_A0811 NC_012441.1 778803 779309 R SmpA/OmlA domain-containing protein complement(778803..779309) Brucella melitensis ATCC 23457 7677900 YP_002732522.1 CDS BMEA_A0812 NC_012441.1 779411 779965 D ubiquinol-cytochrome C chaperone 779411..779965 Brucella melitensis ATCC 23457 7677901 YP_002732523.1 CDS BMEA_A0813 NC_012441.1 780085 780642 D hypothetical protein 780085..780642 Brucella melitensis ATCC 23457 7677902 YP_002732524.1 CDS plsX NC_012441.1 780760 781800 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 780760..781800 Brucella melitensis ATCC 23457 7677903 YP_002732525.1 CDS fabH NC_012441.1 782048 783019 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 782048..783019 Brucella melitensis ATCC 23457 7677904 YP_002732526.1 CDS ihfA NC_012441.1 783138 783461 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 783138..783461 Brucella melitensis ATCC 23457 7677905 YP_002732527.1 CDS BMEA_A0817 NC_012441.1 783995 784537 D MerR family transcriptional regulator 783995..784537 Brucella melitensis ATCC 23457 7677906 YP_002732528.1 CDS BMEA_A0818 NC_012441.1 784587 784904 R quaternary ammonium compound-resistance protein SugE complement(784587..784904) Brucella melitensis ATCC 23457 7677907 YP_002732529.1 CDS BMEA_A0820 NC_012441.1 785250 786788 R exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase complement(785250..786788) Brucella melitensis ATCC 23457 7677909 YP_002732530.1 CDS BMEA_A0821 NC_012441.1 786918 787133 R group 1 glycosyl transferase complement(786918..787133) Brucella melitensis ATCC 23457 7677910 YP_002732531.1 CDS BMEA_A0822 NC_012441.1 787142 787729 R polysaccharide export protein complement(787142..787729) Brucella melitensis ATCC 23457 7677911 YP_002732532.1 CDS BMEA_A0823 NC_012441.1 787853 788515 D exopolysaccharide transport protein family protein 787853..788515 Brucella melitensis ATCC 23457 7677912 YP_002732533.1 CDS BMEA_A0824 NC_012441.1 788583 788801 R hypothetical protein complement(788583..788801) Brucella melitensis ATCC 23457 7677913 YP_002732534.1 CDS BMEA_A0825 NC_012441.1 789153 790229 D cytochrome oxidase assembly 789153..790229 Brucella melitensis ATCC 23457 7677914 YP_002732535.1 CDS argC NC_012441.1 790382 791314 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase complement(790382..791314) Brucella melitensis ATCC 23457 7677915 YP_002732536.1 CDS speB NC_012441.1 791404 792354 R catalyzes the formation of putrescine from agmatine; agmatinase complement(791404..792354) Brucella melitensis ATCC 23457 7677916 YP_002732537.1 CDS BMEA_A0828 NC_012441.1 792445 792921 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(792445..792921) Brucella melitensis ATCC 23457 7677917 YP_002732538.1 CDS rplM NC_012441.1 792924 793388 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(792924..793388) Brucella melitensis ATCC 23457 7677918 YP_002732539.1 CDS BMEA_A0830 NC_012441.1 793624 794070 R thioesterase superfamily protein complement(793624..794070) Brucella melitensis ATCC 23457 7677919 YP_002732540.1 CDS BMEA_A0831 NC_012441.1 794304 795587 D catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 794304..795587 Brucella melitensis ATCC 23457 7677920 YP_002732541.1 CDS BMEA_A0832 NC_012441.1 795659 796048 R hypothetical protein complement(795659..796048) Brucella melitensis ATCC 23457 7677921 YP_002732542.1 CDS BMEA_A0833 NC_012441.1 796288 796419 D hypothetical protein 796288..796419 Brucella melitensis ATCC 23457 7677922 YP_002732543.1 CDS BMEA_A0834 NC_012441.1 796740 797108 D transposase 796740..797108 Brucella melitensis ATCC 23457 7677923 YP_002732544.1 CDS BMEA_A0835 NC_012441.1 797105 797497 D IS4 transposase 797105..797497 Brucella melitensis ATCC 23457 7677924 YP_002732545.1 CDS BMEA_A0836 NC_012441.1 797517 798026 D hypothetical protein 797517..798026 Brucella melitensis ATCC 23457 7677925 YP_002732546.1 CDS BMEA_A0837 NC_012441.1 798023 798418 D hypothetical protein 798023..798418 Brucella melitensis ATCC 23457 7677926 YP_002732547.1 CDS BMEA_A0838 NC_012441.1 798472 798807 D hypothetical protein 798472..798807 Brucella melitensis ATCC 23457 7677927 YP_002732548.1 CDS BMEA_A0839 NC_012441.1 798864 799265 R hypothetical protein complement(798864..799265) Brucella melitensis ATCC 23457 7677928 YP_002732549.1 CDS BMEA_A0841 NC_012441.1 799562 799744 D hypothetical protein 799562..799744 Brucella melitensis ATCC 23457 7677930 YP_002732550.1 CDS BMEA_A0843 NC_012441.1 800129 800332 R hypothetical protein complement(800129..800332) Brucella melitensis ATCC 23457 7677932 YP_002732551.1 CDS BMEA_A0844 NC_012441.1 800840 801205 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 800840..801205 Brucella melitensis ATCC 23457 7677933 YP_002732552.1 CDS BMEA_A0845 NC_012441.1 801196 801777 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 801196..801777 Brucella melitensis ATCC 23457 7677934 YP_002732553.1 CDS nuoC NC_012441.1 801890 802498 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 801890..802498 Brucella melitensis ATCC 23457 7677935 YP_002732554.1 CDS nuoD NC_012441.1 802516 803706 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 802516..803706 Brucella melitensis ATCC 23457 7677936 YP_002732555.1 CDS nuoE NC_012441.1 803706 804419 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 803706..804419 Brucella melitensis ATCC 23457 7677937 YP_002732556.1 CDS nuoF NC_012441.1 804423 805730 D part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 804423..805730 Brucella melitensis ATCC 23457 7677938 YP_002732557.1 CDS BMEA_A0850 NC_012441.1 805865 807949 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 805865..807949 Brucella melitensis ATCC 23457 7677939 YP_002732558.1 CDS BMEA_A0851 NC_012441.1 807969 809012 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 807969..809012 Brucella melitensis ATCC 23457 7677940 YP_002732559.1 CDS BMEA_A0852 NC_012441.1 809025 809516 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 809025..809516 Brucella melitensis ATCC 23457 7677941 YP_002732560.1 CDS BMEA_A0853 NC_012441.1 809690 810307 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 809690..810307 Brucella melitensis ATCC 23457 7677942 YP_002732561.1 CDS BMEA_A0854 NC_012441.1 810318 810626 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 810318..810626 Brucella melitensis ATCC 23457 7677943 YP_002732562.1 CDS BMEA_A0855 NC_012441.1 810634 812619 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 810634..812619 Brucella melitensis ATCC 23457 7677944 YP_002732563.1 CDS BMEA_A0856 NC_012441.1 812619 814127 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 812619..814127 Brucella melitensis ATCC 23457 7677945 YP_002732564.1 CDS BMEA_A0857 NC_012441.1 814149 815585 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 814149..815585 Brucella melitensis ATCC 23457 7677946 YP_002732565.1 CDS BMEA_A0858 NC_012441.1 815611 816408 D biotin--acetyl-CoA-carboxylase ligase 815611..816408 Brucella melitensis ATCC 23457 7677947 YP_002732566.1 CDS BMEA_A0859 NC_012441.1 816602 818278 D hypothetical protein 816602..818278 Brucella melitensis ATCC 23457 7677948 YP_002732567.1 CDS mce NC_012441.1 818318 818722 D methylmalonyl-CoA epimerase 818318..818722 Brucella melitensis ATCC 23457 7677949 YP_002732568.1 CDS BMEA_A0861 NC_012441.1 818725 818994 D hypothetical protein 818725..818994 Brucella melitensis ATCC 23457 7677950 YP_002732569.1 CDS proS NC_012441.1 819842 821170 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 819842..821170 Brucella melitensis ATCC 23457 7677951 YP_002732570.1 CDS BMEA_A0863 NC_012441.1 821212 822480 D lipoprotein releasing system, transmembrane protein, LolC/E family protein 821212..822480 Brucella melitensis ATCC 23457 7677952 YP_002732571.1 CDS BMEA_A0864 NC_012441.1 822480 823163 D lipoprotein-releasing system ATP-binding protein lolD 822480..823163 Brucella melitensis ATCC 23457 7677953 YP_002732572.1 CDS dnaE NC_012441.1 823822 827313 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 823822..827313 Brucella melitensis ATCC 23457 7677954 YP_002732573.1 CDS BMEA_A0866 NC_012441.1 827354 827551 D hypothetical protein 827354..827551 Brucella melitensis ATCC 23457 7677955 YP_002732574.1 CDS BMEA_A0867 NC_012441.1 827596 828009 R hypothetical protein complement(827596..828009) Brucella melitensis ATCC 23457 7677956 YP_002732575.1 CDS BMEA_A0868 NC_012441.1 828281 829303 R extensin family protein complement(828281..829303) Brucella melitensis ATCC 23457 7677957 YP_002732576.1 CDS rpsD NC_012441.1 829587 830204 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 829587..830204 Brucella melitensis ATCC 23457 7677958 YP_002732577.1 CDS BMEA_A0870 NC_012441.1 830734 831615 D PP-loop domain-containing protein 830734..831615 Brucella melitensis ATCC 23457 7677959 YP_002732578.1 CDS BMEA_A0871 NC_012441.1 831602 832429 D inositol monophosphatase family protein 831602..832429 Brucella melitensis ATCC 23457 7677960 YP_002732579.1 CDS BMEA_A0872 NC_012441.1 832644 833909 R drug resistance transporter, Bcr/CflA subfamily protein complement(832644..833909) Brucella melitensis ATCC 23457 7677961 YP_002732580.1 CDS BMEA_A0873 NC_012441.1 833908 834093 D hypothetical protein 833908..834093 Brucella melitensis ATCC 23457 7677962 YP_002732581.1 CDS BMEA_A0874 NC_012441.1 834180 834512 R glutaredoxin-like protein complement(834180..834512) Brucella melitensis ATCC 23457 7677963 YP_002732582.1 CDS BMEA_A0875 NC_012441.1 834697 834930 R hypothetical protein complement(834697..834930) Brucella melitensis ATCC 23457 7677640 YP_002732583.1 CDS purL NC_012441.1 835200 837422 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(835200..837422) Brucella melitensis ATCC 23457 7677641 YP_002732584.1 CDS BMEA_A0877 NC_012441.1 837609 838010 R hypothetical protein complement(837609..838010) Brucella melitensis ATCC 23457 7677642 YP_002732585.1 CDS BMEA_A0878 NC_012441.1 838070 838717 R glutathione S-transferase domain-containing protein complement(838070..838717) Brucella melitensis ATCC 23457 7677643 YP_002732586.1 CDS purQ NC_012441.1 838969 839640 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I complement(838969..839640) Brucella melitensis ATCC 23457 7677644 YP_002732587.1 CDS purS NC_012441.1 839663 839905 R With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS complement(839663..839905) Brucella melitensis ATCC 23457 7677645 YP_002732588.1 CDS purC NC_012441.1 840021 840785 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(840021..840785) Brucella melitensis ATCC 23457 7677646 YP_002732589.1 CDS BMEA_A0882 NC_012441.1 841041 841364 D hypothetical protein 841041..841364 Brucella melitensis ATCC 23457 7677647 YP_002732590.1 CDS BMEA_A0883 NC_012441.1 841429 842196 D 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 841429..842196 Brucella melitensis ATCC 23457 7677648 YP_002732591.1 CDS BMEA_A0884 NC_012441.1 842245 842811 R hypothetical protein complement(842245..842811) Brucella melitensis ATCC 23457 7677649 YP_002732592.1 CDS BMEA_A0885 NC_012441.1 842834 842935 D hypothetical protein 842834..842935 Brucella melitensis ATCC 23457 7677650 YP_002732593.1 CDS BMEA_A0886 NC_012441.1 843080 843955 D biphenyl-2,3-diol 1,2-dioxygenase 3 843080..843955 Brucella melitensis ATCC 23457 7677651 YP_002732594.1 CDS purB NC_012441.1 844181 845482 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(844181..845482) Brucella melitensis ATCC 23457 7677652 YP_002732595.1 CDS rpe NC_012441.1 845509 846186 R ribulose-phosphate 3-epimerase complement(845509..846186) Brucella melitensis ATCC 23457 7677653 YP_002732596.1 CDS BMEA_A0889 NC_012441.1 846344 847270 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(846344..847270) Brucella melitensis ATCC 23457 7677654 YP_002732597.1 CDS BMEA_A0890 NC_012441.1 847284 848312 R hypothetical protein complement(847284..848312) Brucella melitensis ATCC 23457 7677655 YP_002732598.1 CDS BMEA_A0891 NC_012441.1 848394 849671 R FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-(acyl carrier protein) synthase II complement(848394..849671) Brucella melitensis ATCC 23457 7677656 YP_002732599.1 CDS BMEA_A0892 NC_012441.1 849673 850854 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(849673..850854) Brucella melitensis ATCC 23457 7677657 YP_002732600.1 CDS BMEA_A0893 NC_012441.1 851002 851283 R Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein complement(851002..851283) Brucella melitensis ATCC 23457 7677658 YP_002732601.1 CDS BMEA_A0894 NC_012441.1 851484 852245 R hypothetical protein complement(851484..852245) Brucella melitensis ATCC 23457 7677659 YP_002732602.1 CDS BMEA_A0895 NC_012441.1 852461 853483 D aldose 1-epimerase 852461..853483 Brucella melitensis ATCC 23457 7677660 YP_002732603.1 CDS BMEA_A0896 NC_012441.1 853480 854397 R 2-dehydro-3-deoxygluconokinase complement(853480..854397) Brucella melitensis ATCC 23457 7677661 YP_002732604.1 CDS BMEA_A0897 NC_012441.1 854586 855317 D phosphonate metabolism protein 854586..855317 Brucella melitensis ATCC 23457 7677662 YP_002732605.1 CDS phnM NC_012441.1 855321 856460 D phosphonate metabolism protein PhnM 855321..856460 Brucella melitensis ATCC 23457 7677663 YP_002732606.1 CDS BMEA_A0899 NC_012441.1 856457 857140 R HAD-superfamily hydrolase complement(856457..857140) Brucella melitensis ATCC 23457 7677664 YP_002732607.1 CDS BMEA_A0900 NC_012441.1 857397 858185 D family 3 extracellular solute-binding protein 857397..858185 Brucella melitensis ATCC 23457 7677665 YP_002732608.1 CDS BMEA_A0901 NC_012441.1 858377 859399 D tRNA-dihydrouridine synthase A 858377..859399 Brucella melitensis ATCC 23457 7677666 YP_002732609.1 CDS BMEA_A0902 NC_012441.1 859396 860100 R hypothetical protein complement(859396..860100) Brucella melitensis ATCC 23457 7677667 YP_002732610.1 CDS BMEA_A0903 NC_012441.1 860100 860249 R hypothetical protein complement(860100..860249) Brucella melitensis ATCC 23457 7677668 YP_002732611.1 CDS cobS NC_012441.1 860314 861096 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(860314..861096) Brucella melitensis ATCC 23457 7677669 YP_002732612.1 CDS cobT NC_012441.1 861250 862269 D catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 861250..862269 Brucella melitensis ATCC 23457 7677670 YP_002732613.1 CDS BMEA_A0906 NC_012441.1 862377 862856 R hypothetical protein complement(862377..862856) Brucella melitensis ATCC 23457 7677671 YP_002732614.1 CDS BMEA_A0907 NC_012441.1 862985 863626 R hypothetical protein complement(862985..863626) Brucella melitensis ATCC 23457 7677672 YP_002732615.1 CDS BMEA_A0908 NC_012441.1 863723 864292 R nuclease, SNase domain-containing protein complement(863723..864292) Brucella melitensis ATCC 23457 7677673 YP_002732616.1 CDS BMEA_A0909 NC_012441.1 864263 864541 D hypothetical protein 864263..864541 Brucella melitensis ATCC 23457 7677674 YP_002732617.1 CDS BMEA_A0910 NC_012441.1 864913 865716 D exopolysaccharide production negative regulator 864913..865716 Brucella melitensis ATCC 23457 7677675 YP_002732618.1 CDS BMEA_A0911 NC_012441.1 865775 866557 R exodeoxyribonuclease III Xth complement(865775..866557) Brucella melitensis ATCC 23457 7677676 YP_002732619.1 CDS BMEA_A0912 NC_012441.1 866726 867433 D hypothetical protein 866726..867433 Brucella melitensis ATCC 23457 7677677 YP_002732620.1 CDS BMEA_A0913 NC_012441.1 867514 867840 R iron-sulfur cluster assembly accessory protein complement(867514..867840) Brucella melitensis ATCC 23457 7677678 YP_002732621.1 CDS dgt NC_012441.1 868007 869215 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 868007..869215 Brucella melitensis ATCC 23457 7677679 YP_002732622.1 CDS argS NC_012441.1 869437 871194 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 869437..871194 Brucella melitensis ATCC 23457 7677680 YP_002732623.1 CDS BMEA_A0916 NC_012441.1 871406 874378 D oleosin-B6 871406..874378 Brucella melitensis ATCC 23457 7677681 YP_002732624.1 CDS BMEA_A0917 NC_012441.1 874579 875598 D beta-hexosaminidase A 874579..875598 Brucella melitensis ATCC 23457 7677682 YP_002732625.1 CDS BMEA_A0918 NC_012441.1 875671 876522 D chromosome segregation and condensation protein ScpA 875671..876522 Brucella melitensis ATCC 23457 7677683 YP_002732626.1 CDS scpB NC_012441.1 876515 877240 D segregation and condensation protein B 876515..877240 Brucella melitensis ATCC 23457 7677684 YP_002732627.1 CDS tatA NC_012441.1 877386 877604 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 877386..877604 Brucella melitensis ATCC 23457 7677685 YP_002732628.1 CDS tatB NC_012441.1 877685 878281 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 877685..878281 Brucella melitensis ATCC 23457 7677686 YP_002732629.1 CDS tatC NC_012441.1 878278 879102 D Sec-independent protein translocase TatC 878278..879102 Brucella melitensis ATCC 23457 7677687 YP_002732630.1 CDS serS NC_012441.1 879179 880462 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 879179..880462 Brucella melitensis ATCC 23457 7677688 YP_002732631.1 CDS surE NC_012441.1 880611 881378 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 880611..881378 Brucella melitensis ATCC 23457 7677689 YP_002732632.1 CDS BMEA_A0925 NC_012441.1 881375 882043 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 881375..882043 Brucella melitensis ATCC 23457 7677690 YP_002732633.1 CDS BMEA_A0926 NC_012441.1 882188 882373 D hypothetical protein 882188..882373 Brucella melitensis ATCC 23457 7677691 YP_002732634.1 CDS BMEA_A0927 NC_012441.1 882422 883720 D peptidase M23B 882422..883720 Brucella melitensis ATCC 23457 7677692 YP_002732635.1 CDS BMEA_A0928 NC_012441.1 883769 884635 R hypothetical protein complement(883769..884635) Brucella melitensis ATCC 23457 7677693 YP_002732636.1 CDS yajC NC_012441.1 884795 885136 D preprotein translocase subunit YajC 884795..885136 Brucella melitensis ATCC 23457 7677694 YP_002732637.1 CDS secD NC_012441.1 885255 887582 D part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 885255..887582 Brucella melitensis ATCC 23457 7677695 YP_002732638.1 CDS BMEA_A0931 NC_012441.1 887585 887974 D hypothetical protein 887585..887974 Brucella melitensis ATCC 23457 7677696 YP_002732639.1 CDS BMEA_A0932 NC_012441.1 887980 888813 D phytoene synthase 887980..888813 Brucella melitensis ATCC 23457 7677697 YP_002732640.1 CDS gid NC_012441.1 888865 890265 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(888865..890265) Brucella melitensis ATCC 23457 7677698 YP_002732641.1 CDS BMEA_A0934 NC_012441.1 890507 890653 R hypothetical protein complement(890507..890653) Brucella melitensis ATCC 23457 7677699 YP_002732642.1 CDS BMEA_A0935 NC_012441.1 890927 892063 D hypothetical protein 890927..892063 Brucella melitensis ATCC 23457 7677700 YP_002732643.1 CDS BMEA_A0936 NC_012441.1 892060 892629 D hypothetical protein 892060..892629 Brucella melitensis ATCC 23457 7677701 YP_002732644.1 CDS tig NC_012441.1 893009 894466 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 893009..894466 Brucella melitensis ATCC 23457 7677703 YP_002732645.1 CDS gatB NC_012441.1 894616 896118 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 894616..896118 Brucella melitensis ATCC 23457 7677704 YP_002732646.1 CDS BMEA_A0940 NC_012441.1 896118 896621 D N-acetyltransferase GCN5 896118..896621 Brucella melitensis ATCC 23457 7677705 YP_002732647.1 CDS BMEA_A0941 NC_012441.1 896781 897191 D Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 896781..897191 Brucella melitensis ATCC 23457 7677706 YP_002732648.1 CDS BMEA_A0942 NC_012441.1 897251 897376 D hypothetical protein 897251..897376 Brucella melitensis ATCC 23457 7677707 YP_002732649.1 CDS BMEA_A0943 NC_012441.1 897385 897855 D hypothetical protein 897385..897855 Brucella melitensis ATCC 23457 7677708 YP_002732650.1 CDS aat NC_012441.1 897899 898513 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(897899..898513) Brucella melitensis ATCC 23457 7677709 YP_002732651.1 CDS accC NC_012441.1 898519 899877 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit complement(898519..899877) Brucella melitensis ATCC 23457 7677710 YP_002732652.1 CDS accB NC_012441.1 899927 900397 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(899927..900397) Brucella melitensis ATCC 23457 7677711 YP_002732653.1 CDS aroQ NC_012441.1 900399 900872 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(900399..900872) Brucella melitensis ATCC 23457 7677712 YP_002732654.1 CDS BMEA_A0948 NC_012441.1 901116 901913 R DSBA oxidoreductase complement(901116..901913) Brucella melitensis ATCC 23457 7677713 YP_002732655.1 CDS BMEA_A0949 NC_012441.1 901961 903376 R peptidase M48 Ste24p complement(901961..903376) Brucella melitensis ATCC 23457 7677714 YP_002732656.1 CDS BMEA_A0950 NC_012441.1 903568 904731 D class I and II aminotransferase 903568..904731 Brucella melitensis ATCC 23457 7677715 YP_002732657.1 CDS BMEA_A0951 NC_012441.1 904850 907525 R ribonuclease, Rne/Rng family protein complement(904850..907525) Brucella melitensis ATCC 23457 7677716 YP_002732658.1 CDS BMEA_A0952 NC_012441.1 907528 907713 D hypothetical protein 907528..907713 Brucella melitensis ATCC 23457 7677717 YP_002732659.1 CDS BMEA_A0953 NC_012441.1 908204 909472 D N-acetylmuramoyl-L-alanine amidase 908204..909472 Brucella melitensis ATCC 23457 7677718 YP_002732660.1 CDS BMEA_A0954 NC_012441.1 909752 912211 D 1A family penicillin-binding protein 909752..912211 Brucella melitensis ATCC 23457 7677719 YP_002732661.1 CDS BMEA_A0955 NC_012441.1 912267 912398 R hypothetical protein complement(912267..912398) Brucella melitensis ATCC 23457 7677720 YP_002732662.1 CDS prfB NC_012441.1 912515 913480 D catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; peptide chain release factor 2 912515..913480 Brucella melitensis ATCC 23457 7677017 YP_002732663.1 CDS BMEA_A0957 NC_012441.1 913539 913703 R hypothetical protein complement(913539..913703) Brucella melitensis ATCC 23457 7677251 YP_002732664.1 CDS BMEA_A0958 NC_012441.1 913674 914042 D transposase 913674..914042 Brucella melitensis ATCC 23457 7677252 YP_002732665.1 CDS BMEA_A0959 NC_012441.1 914039 914317 D IS6501 transposase 914039..914317 Brucella melitensis ATCC 23457 7677253 YP_002732666.1 CDS BMEA_A0960 NC_012441.1 914584 914946 R peptidase M23B complement(914584..914946) Brucella melitensis ATCC 23457 7677254 YP_002732667.1 CDS BMEA_A0961 NC_012441.1 915117 915944 R hypothetical protein complement(915117..915944) Brucella melitensis ATCC 23457 7677255 YP_002732668.1 CDS BMEA_A0962 NC_012441.1 915966 916430 R alkyl hydroperoxide reductase complement(915966..916430) Brucella melitensis ATCC 23457 7677256 YP_002732669.1 CDS BMEA_A0963 NC_012441.1 916675 920115 D hypothetical protein 916675..920115 Brucella melitensis ATCC 23457 7677257 YP_002732670.1 CDS tyrS NC_012441.1 920174 921427 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(920174..921427) Brucella melitensis ATCC 23457 7677258 YP_002732671.1 CDS BMEA_A0965 NC_012441.1 921543 922664 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 921543..922664 Brucella melitensis ATCC 23457 7677259 YP_002732672.1 CDS BMEA_A0966 NC_012441.1 922661 922993 R quaternary ammonium compound-resistance protein QacF complement(922661..922993) Brucella melitensis ATCC 23457 7677260 YP_002732673.1 CDS BMEA_A0967 NC_012441.1 923105 923779 R hypothetical protein complement(923105..923779) Brucella melitensis ATCC 23457 7677261 YP_002732674.1 CDS BMEA_A0968 NC_012441.1 923983 925161 D cysteine desulfurase 923983..925161 Brucella melitensis ATCC 23457 7677262 YP_002732675.1 CDS sufB NC_012441.1 925342 926865 D with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 925342..926865 Brucella melitensis ATCC 23457 7677263 YP_002732676.1 CDS sufC NC_012441.1 926933 927688 D FeS assembly ATPase SufC 926933..927688 Brucella melitensis ATCC 23457 7677264 YP_002732677.1 CDS sufD NC_012441.1 927702 928979 D FeS assembly protein SufD 927702..928979 Brucella melitensis ATCC 23457 7677265 YP_002732678.1 CDS sufS NC_012441.1 929061 930305 D cysteine desulfurase 929061..930305 Brucella melitensis ATCC 23457 7677266 YP_002732679.1 CDS BMEA_A0973 NC_012441.1 930302 930721 D FeS assembly SUF system protein 930302..930721 Brucella melitensis ATCC 23457 7677267 YP_002732680.1 CDS BMEA_A0974 NC_012441.1 930755 931726 R group 2 family glycosyl transferase complement(930755..931726) Brucella melitensis ATCC 23457 7677268 YP_002732681.1 CDS BMEA_A0976 NC_012441.1 932153 932926 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 932153..932926 Brucella melitensis ATCC 23457 7677270 YP_002732682.1 CDS BMEA_A0977 NC_012441.1 933254 934702 D ATP-dependent RNA helicase Dbp2 933254..934702 Brucella melitensis ATCC 23457 7677271 YP_002732683.1 CDS sufA NC_012441.1 934939 935319 R FeS assembly scaffold SufA complement(934939..935319) Brucella melitensis ATCC 23457 7677272 YP_002732684.1 CDS BMEA_A0979 NC_012441.1 935512 936135 D hypothetical protein 935512..936135 Brucella melitensis ATCC 23457 7677273 YP_002732685.1 CDS BMEA_A0980 NC_012441.1 936120 936212 D hypothetical protein 936120..936212 Brucella melitensis ATCC 23457 7677274 YP_002732686.1 CDS BMEA_A0981 NC_012441.1 936216 936416 D heavy metal transport/detoxification protein 936216..936416 Brucella melitensis ATCC 23457 7677275 YP_002732687.1 CDS BMEA_A0983 NC_012441.1 936745 937413 D protein-L-isoaspartate O-methyltransferase 936745..937413 Brucella melitensis ATCC 23457 7677277 YP_002732688.1 CDS BMEA_A0984 NC_012441.1 937552 938922 D type I secretion outer membrane protein 937552..938922 Brucella melitensis ATCC 23457 7677278 YP_002732689.1 CDS BMEA_A0985 NC_012441.1 939172 939903 D hypothetical protein 939172..939903 Brucella melitensis ATCC 23457 7677279 YP_002732690.1 CDS valS NC_012441.1 940194 942926 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 940194..942926 Brucella melitensis ATCC 23457 7677280 YP_002732691.1 CDS BMEA_A0987 NC_012441.1 943290 943619 D hypothetical protein 943290..943619 Brucella melitensis ATCC 23457 7677281 YP_002732692.1 CDS BMEA_A0988 NC_012441.1 943728 944618 D outer membrane protein E 943728..944618 Brucella melitensis ATCC 23457 7677282 YP_002732693.1 CDS BMEA_A0989 NC_012441.1 944684 945559 R 6-phosphogluconate dehydrogenase complement(944684..945559) Brucella melitensis ATCC 23457 7677283 YP_002732694.1 CDS mobB NC_012441.1 946679 947152 R molybdopterin-guanine dinucleotide biosynthesis protein B complement(946679..947152) Brucella melitensis ATCC 23457 7677284 YP_002732695.1 CDS mobA NC_012441.1 947178 947843 R molybdopterin-guanine dinucleotide biosynthesis protein A complement(947178..947843) Brucella melitensis ATCC 23457 7677285 YP_002732696.1 CDS moaA NC_012441.1 948019 949053 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(948019..949053) Brucella melitensis ATCC 23457 7677286 YP_002732697.1 CDS BMEA_A0993 NC_012441.1 949240 949599 D hypothetical protein 949240..949599 Brucella melitensis ATCC 23457 7677287 YP_002732698.1 CDS BMEA_A0994 NC_012441.1 949667 950773 R monooxygenase FAD-binding complement(949667..950773) Brucella melitensis ATCC 23457 7677288 YP_002732699.1 CDS BMEA_A0995 NC_012441.1 951119 952738 R Fe-S type, tartrate/fumarate subfamily hydro-lyase subunit alpha complement(951119..952738) Brucella melitensis ATCC 23457 7677289 YP_002732700.1 CDS BMEA_A0996 NC_012441.1 953144 953431 D peptidoglycan-binding domain 1 protein 953144..953431 Brucella melitensis ATCC 23457 7677290 YP_002732701.1 CDS BMEA_A0997 NC_012441.1 953516 955048 D peptidoglycan-binding domain 1 protein 953516..955048 Brucella melitensis ATCC 23457 7677291 YP_002732702.1 CDS BMEA_A1000 NC_012441.1 955849 956100 R transglycosylase-associated protein complement(955849..956100) Brucella melitensis ATCC 23457 7677294 YP_002732703.1 CDS BMEA_A1001 NC_012441.1 956255 956416 D hypothetical protein 956255..956416 Brucella melitensis ATCC 23457 7677295 YP_002732704.1 CDS BMEA_A1003 NC_012441.1 956609 957634 R phage-related integrase complement(956609..957634) Brucella melitensis ATCC 23457 7677297 YP_002732705.1 CDS BMEA_A1004 NC_012441.1 958039 958242 R hypothetical protein complement(958039..958242) Brucella melitensis ATCC 23457 7677298 YP_002732706.1 CDS BMEA_A1005 NC_012441.1 958428 958997 D hypothetical protein 958428..958997 Brucella melitensis ATCC 23457 7677299 YP_002732707.1 CDS BMEA_A1006 NC_012441.1 958994 959224 D hypothetical protein 958994..959224 Brucella melitensis ATCC 23457 7677300 YP_002732708.1 CDS BMEA_A1007 NC_012441.1 959221 959496 D hypothetical protein 959221..959496 Brucella melitensis ATCC 23457 7677301 YP_002732709.1 CDS BMEA_A1008 NC_012441.1 959519 959995 D hypothetical protein 959519..959995 Brucella melitensis ATCC 23457 7677302 YP_002732710.1 CDS BMEA_A1009 NC_012441.1 960341 961051 D porin 960341..961051 Brucella melitensis ATCC 23457 7677303 YP_002732711.1 CDS BMEA_A1010 NC_012441.1 961399 961569 R hypothetical protein complement(961399..961569) Brucella melitensis ATCC 23457 7677304 YP_002732712.1 CDS BMEA_A1011 NC_012441.1 961587 961766 D hypothetical protein 961587..961766 Brucella melitensis ATCC 23457 7677305 YP_002732713.1 CDS BMEA_A1012 NC_012441.1 961917 962231 R hypothetical protein complement(961917..962231) Brucella melitensis ATCC 23457 7677306 YP_002732714.1 CDS BMEA_A1013 NC_012441.1 962231 962551 R hypothetical protein complement(962231..962551) Brucella melitensis ATCC 23457 7677307 YP_002732715.1 CDS BMEA_A1014 NC_012441.1 962639 963247 D queuine tRNA-ribosyltransferase 962639..963247 Brucella melitensis ATCC 23457 7677308 YP_002732716.1 CDS BMEA_A1015 NC_012441.1 963317 963685 D transposase 963317..963685 Brucella melitensis ATCC 23457 7677309 YP_002732717.1 CDS BMEA_A1016 NC_012441.1 963682 963960 D IS6501 transposase 963682..963960 Brucella melitensis ATCC 23457 7677310 YP_002732718.1 CDS BMEA_A1017 NC_012441.1 964076 964768 D hypothetical protein 964076..964768 Brucella melitensis ATCC 23457 7677311 YP_002732719.1 CDS BMEA_A1018 NC_012441.1 964966 965088 D hypothetical protein 964966..965088 Brucella melitensis ATCC 23457 7677312 YP_002732720.1 CDS BMEA_A1020 NC_012441.1 966957 968189 D hypothetical protein 966957..968189 Brucella melitensis ATCC 23457 7677314 YP_002732721.1 CDS BMEA_A1021 NC_012441.1 968186 969745 D hypothetical protein 968186..969745 Brucella melitensis ATCC 23457 7677315 YP_002732722.1 CDS BMEA_A1022 NC_012441.1 969726 969947 R hypothetical protein complement(969726..969947) Brucella melitensis ATCC 23457 7677316 YP_002732723.1 CDS BMEA_A1023 NC_012441.1 970092 970850 D hypothetical protein 970092..970850 Brucella melitensis ATCC 23457 7677317 YP_002732724.1 CDS BMEA_A1025 NC_012441.1 971240 971482 D hypothetical protein 971240..971482 Brucella melitensis ATCC 23457 7677318 YP_002732725.1 CDS BMEA_A1027 NC_012441.1 971584 971685 D hypothetical protein 971584..971685 Brucella melitensis ATCC 23457 7677319 YP_002732726.1 CDS BMEA_A1028 NC_012441.1 971694 971831 D hypothetical protein 971694..971831 Brucella melitensis ATCC 23457 7677320 YP_002732727.1 CDS arsC NC_012441.1 971822 972169 D arsenate reductase 971822..972169 Brucella melitensis ATCC 23457 7677321 YP_002732728.1 CDS rlpA NC_012441.1 972540 973805 D rare lipoprotein A 972540..973805 Brucella melitensis ATCC 23457 7677322 YP_002732729.1 CDS BMEA_A1032 NC_012441.1 973916 975106 D serine-type D-Ala-D-Ala carboxypeptidase 973916..975106 Brucella melitensis ATCC 23457 7677323 YP_002732730.1 CDS tmk NC_012441.1 975188 975832 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 975188..975832 Brucella melitensis ATCC 23457 7677324 YP_002732731.1 CDS holB NC_012441.1 975829 976911 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 975829..976911 Brucella melitensis ATCC 23457 7677325 YP_002732732.1 CDS BMEA_A1035 NC_012441.1 976931 977080 D hypothetical protein 976931..977080 Brucella melitensis ATCC 23457 7677326 YP_002732733.1 CDS metG NC_012441.1 977080 978627 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 977080..978627 Brucella melitensis ATCC 23457 7677327 YP_002732734.1 CDS BMEA_A1037 NC_012441.1 978636 979427 D TatD family hydrolase 978636..979427 Brucella melitensis ATCC 23457 7677328 YP_002732735.1 CDS BMEA_A1038 NC_012441.1 979430 980248 D beta-lactamase domain-containing protein 979430..980248 Brucella melitensis ATCC 23457 7677329 YP_002732736.1 CDS BMEA_A1039 NC_012441.1 980298 982097 R responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABc transporter complement(980298..982097) Brucella melitensis ATCC 23457 7677330 YP_002732737.1 CDS BMEA_A1040 NC_012441.1 982232 982366 D hypothetical protein 982232..982366 Brucella melitensis ATCC 23457 7676201 YP_002732738.1 CDS BMEA_A1041 NC_012441.1 982410 983390 D RluA family pseudouridine synthase 982410..983390 Brucella melitensis ATCC 23457 7677802 YP_002732739.1 CDS BMEA_A1042 NC_012441.1 983393 984316 D hypothetical protein 983393..984316 Brucella melitensis ATCC 23457 7677803 YP_002732740.1 CDS BMEA_A1043 NC_012441.1 984313 984963 D HAD-superfamily hydrolase 984313..984963 Brucella melitensis ATCC 23457 7677804 YP_002732741.1 CDS BMEA_A1044 NC_012441.1 985005 985787 D ATPase 985005..985787 Brucella melitensis ATCC 23457 7677805 YP_002732742.1 CDS glnA NC_012441.1 985913 987322 R glutamine synthetase, type I complement(985913..987322) Brucella melitensis ATCC 23457 7677806 YP_002732743.1 CDS BMEA_A1046 NC_012441.1 987470 987808 R nitrogen regulatory protein P-II complement(987470..987808) Brucella melitensis ATCC 23457 7677807 YP_002732744.1 CDS BMEA_A1047 NC_012441.1 988115 989620 D YjeF family protein 988115..989620 Brucella melitensis ATCC 23457 7677808 YP_002732745.1 CDS BMEA_A1048 NC_012441.1 989651 989842 R hypothetical protein complement(989651..989842) Brucella melitensis ATCC 23457 7677809 YP_002732746.1 CDS gph NC_012441.1 989920 990624 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(989920..990624) Brucella melitensis ATCC 23457 7677810 YP_002732747.1 CDS BMEA_A1050 NC_012441.1 990679 990792 D hypothetical protein 990679..990792 Brucella melitensis ATCC 23457 7677811 YP_002732748.1 CDS rpiA NC_012441.1 990971 991669 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 990971..991669 Brucella melitensis ATCC 23457 7677812 YP_002732749.1 CDS BMEA_A1052 NC_012441.1 991695 992231 D hypothetical protein 991695..992231 Brucella melitensis ATCC 23457 7677813 YP_002732750.1 CDS gor NC_012441.1 992385 993779 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 992385..993779 Brucella melitensis ATCC 23457 7677814 YP_002732751.1 CDS BMEA_A1054 NC_012441.1 993988 995367 D 3-deoxy-7-phosphoheptulonate synthase 993988..995367 Brucella melitensis ATCC 23457 7677815 YP_002732752.1 CDS BMEA_A1055 NC_012441.1 995481 995831 D diacylglycerol kinase 995481..995831 Brucella melitensis ATCC 23457 7677816 YP_002732753.1 CDS nadE NC_012441.1 995896 997575 D NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 995896..997575 Brucella melitensis ATCC 23457 7677817 YP_002732754.1 CDS gltX NC_012441.1 997587 998960 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 997587..998960 Brucella melitensis ATCC 23457 7677818 YP_002732755.1 CDS BMEA_A1058 NC_012441.1 999774 1002098 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(999774..1002098) Brucella melitensis ATCC 23457 7677819 YP_002732756.1 CDS BMEA_A1059 NC_012441.1 1002316 1003296 R mandelate racemase/muconate lactonizing protein complement(1002316..1003296) Brucella melitensis ATCC 23457 7677820 YP_002732757.1 CDS BMEA_A1060 NC_012441.1 1003357 1004532 D hypothetical protein 1003357..1004532 Brucella melitensis ATCC 23457 7677821 YP_002732758.1 CDS BMEA_A1061 NC_012441.1 1004748 1005605 D ABC transporter 1004748..1005605 Brucella melitensis ATCC 23457 7677822 YP_002732759.1 CDS BMEA_A1062 NC_012441.1 1005609 1006604 D mammalian cell entry related domain-containing protein 1005609..1006604 Brucella melitensis ATCC 23457 7677823 YP_002732760.1 CDS BMEA_A1063 NC_012441.1 1006628 1007230 D hypothetical protein 1006628..1007230 Brucella melitensis ATCC 23457 7677824 YP_002732761.1 CDS BMEA_A1064 NC_012441.1 1007470 1012143 R hypothetical protein complement(1007470..1012143) Brucella melitensis ATCC 23457 7677825 YP_002732762.1 CDS BMEA_A1065 NC_012441.1 1012358 1012639 D hypothetical protein 1012358..1012639 Brucella melitensis ATCC 23457 7677826 YP_002732763.1 CDS BMEA_A1066 NC_012441.1 1012758 1013081 D ferredoxin 1012758..1013081 Brucella melitensis ATCC 23457 7677827 YP_002732764.1 CDS BMEA_A1067 NC_012441.1 1013399 1013722 D FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1013399..1013722 Brucella melitensis ATCC 23457 7677828 YP_002732765.1 CDS BMEA_A1068 NC_012441.1 1013727 1014347 R hypothetical protein complement(1013727..1014347) Brucella melitensis ATCC 23457 7677829 YP_002732766.1 CDS folP NC_012441.1 1014505 1015344 D dihydropteroate synthase 1014505..1015344 Brucella melitensis ATCC 23457 7677830 YP_002732767.1 CDS folB NC_012441.1 1015363 1015722 D dihydroneopterin aldolase 1015363..1015722 Brucella melitensis ATCC 23457 7677831 YP_002732768.1 CDS folK NC_012441.1 1015719 1016252 D 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1015719..1016252 Brucella melitensis ATCC 23457 7677832 YP_002732769.1 CDS BMEA_A1073 NC_012441.1 1016367 1016924 R hypothetical protein complement(1016367..1016924) Brucella melitensis ATCC 23457 7677833 YP_002732770.1 CDS BMEA_A1074 NC_012441.1 1017176 1018249 R hypothetical protein complement(1017176..1018249) Brucella melitensis ATCC 23457 7677834 YP_002732771.1 CDS BMEA_A1075 NC_012441.1 1018266 1019705 R hypothetical protein complement(1018266..1019705) Brucella melitensis ATCC 23457 7677835 YP_002732772.1 CDS BMEA_A1076 NC_012441.1 1019798 1020298 R phosphohistidine phosphatase SixA complement(1019798..1020298) Brucella melitensis ATCC 23457 7677836 YP_002732773.1 CDS dksA NC_012441.1 1020695 1021111 D RNA polymerase-binding protein DksA 1020695..1021111 Brucella melitensis ATCC 23457 7677837 YP_002732774.1 CDS BMEA_A1078 NC_012441.1 1021257 1022513 R hypothetical protein complement(1021257..1022513) Brucella melitensis ATCC 23457 7677838 YP_002732775.1 CDS BMEA_A1079 NC_012441.1 1022880 1025576 D PAS domain S-box-containing protein 1022880..1025576 Brucella melitensis ATCC 23457 7677839 YP_002732776.1 CDS BMEA_A1080 NC_012441.1 1025601 1026809 D hypothetical protein 1025601..1026809 Brucella melitensis ATCC 23457 7677840 YP_002732777.1 CDS BMEA_A1081 NC_012441.1 1026840 1028162 D beta-lactamase 1026840..1028162 Brucella melitensis ATCC 23457 7677841 YP_002732778.1 CDS BMEA_A1082 NC_012441.1 1028143 1029369 R mechanosensitive ion channel protein MscS complement(1028143..1029369) Brucella melitensis ATCC 23457 7677842 YP_002732779.1 CDS BMEA_A1083 NC_012441.1 1029459 1033253 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1029459..1033253) Brucella melitensis ATCC 23457 7677843 YP_002732780.1 CDS BMEA_A1084 NC_012441.1 1033306 1033545 D hypothetical protein 1033306..1033545 Brucella melitensis ATCC 23457 7677844 YP_002732781.1 CDS BMEA_A1085 NC_012441.1 1033955 1034443 R diphosphoinositol polyphosphate phosphohydrolase 3 beta complement(1033955..1034443) Brucella melitensis ATCC 23457 7677845 YP_002732782.1 CDS BMEA_A1086 NC_012441.1 1034539 1034673 R hypothetical protein complement(1034539..1034673) Brucella melitensis ATCC 23457 7677846 YP_002732783.1 CDS BMEA_A1087 NC_012441.1 1035571 1036416 R UspA domain-containing protein complement(1035571..1036416) Brucella melitensis ATCC 23457 7677847 YP_002732784.1 CDS BMEA_A1088 NC_012441.1 1036494 1037252 R CinA-like protein complement(1036494..1037252) Brucella melitensis ATCC 23457 7677848 YP_002732785.1 CDS wrbA NC_012441.1 1037413 1038012 D stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1037413..1038012 Brucella melitensis ATCC 23457 7677849 YP_002732786.1 CDS BMEA_A1090 NC_012441.1 1037990 1038139 R hypothetical protein complement(1037990..1038139) Brucella melitensis ATCC 23457 7677850 YP_002732787.1 CDS ilvA NC_012441.1 1038314 1039573 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1038314..1039573 Brucella melitensis ATCC 23457 7677852 YP_002732788.1 CDS BMEA_A1093 NC_012441.1 1039640 1041247 D DEAD/DEAH box helicase 1039640..1041247 Brucella melitensis ATCC 23457 7677853 YP_002732789.1 CDS BMEA_A1094 NC_012441.1 1041418 1042446 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1041418..1042446 Brucella melitensis ATCC 23457 7677854 YP_002732790.1 CDS BMEA_A1095 NC_012441.1 1042449 1043192 D alanyl-tRNA synthetase 1042449..1043192 Brucella melitensis ATCC 23457 7677855 YP_002732791.1 CDS BMEA_A1096 NC_012441.1 1043219 1044073 D 3-mercaptopyruvate sulfurtransferase 1043219..1044073 Brucella melitensis ATCC 23457 7677856 YP_002732792.1 CDS BMEA_A1097 NC_012441.1 1044075 1044596 D N-acetyltransferase GCN5 1044075..1044596 Brucella melitensis ATCC 23457 7677857 YP_002732793.1 CDS BMEA_A1098 NC_012441.1 1044635 1045429 R diguanylate cyclase complement(1044635..1045429) Brucella melitensis ATCC 23457 7677858 YP_002732794.1 CDS BMEA_A1099 NC_012441.1 1045994 1047484 R succinate CoA transferase complement(1045994..1047484) Brucella melitensis ATCC 23457 7677859 YP_002732795.1 CDS BMEA_A1100 NC_012441.1 1047749 1049290 R drug resistance transporter, EmrB/QacA subfamily protein complement(1047749..1049290) Brucella melitensis ATCC 23457 7677860 YP_002732796.1 CDS BMEA_A1101 NC_012441.1 1049290 1050390 R secretion protein HlyD family protein complement(1049290..1050390) Brucella melitensis ATCC 23457 7677861 YP_002732797.1 CDS BMEA_A1102 NC_012441.1 1050784 1051767 D zinc-binding alcohol dehydrogenase family protein 1050784..1051767 Brucella melitensis ATCC 23457 7677862 YP_002732798.1 CDS BMEA_A1103 NC_012441.1 1051811 1052953 R Xaa-Pro dipeptidase complement(1051811..1052953) Brucella melitensis ATCC 23457 7677863 YP_002732799.1 CDS BMEA_A1104 NC_012441.1 1053212 1054042 R methyltransferase type 12 complement(1053212..1054042) Brucella melitensis ATCC 23457 7677864 YP_002732800.1 CDS BMEA_A1105 NC_012441.1 1054151 1055116 R bile acid:sodium symporter complement(1054151..1055116) Brucella melitensis ATCC 23457 7677865 YP_002732801.1 CDS galE NC_012441.1 1055245 1056252 R UDP-glucose 4-epimerase complement(1055245..1056252) Brucella melitensis ATCC 23457 7677866 YP_002732802.1 CDS BMEA_A1108 NC_012441.1 1056397 1057221 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1056397..1057221 Brucella melitensis ATCC 23457 7677867 YP_002732803.1 CDS BMEA_A1109 NC_012441.1 1057230 1057841 R hypothetical protein complement(1057230..1057841) Brucella melitensis ATCC 23457 7677868 YP_002732804.1 CDS BMEA_A1110 NC_012441.1 1057884 1058468 R nitroreductase complement(1057884..1058468) Brucella melitensis ATCC 23457 7677869 YP_002732805.1 CDS BMEA_A1111 NC_012441.1 1058688 1059698 D hypothetical protein 1058688..1059698 Brucella melitensis ATCC 23457 7677870 YP_002732806.1 CDS thrS NC_012441.1 1059753 1061729 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1059753..1061729) Brucella melitensis ATCC 23457 7677871 YP_002732807.1 CDS BMEA_A1114 NC_012441.1 1063283 1063762 R hypothetical protein complement(1063283..1063762) Brucella melitensis ATCC 23457 7677873 YP_002732808.1 CDS BMEA_A1115 NC_012441.1 1063656 1064096 R nitrogen-fixing NifU domain-containing protein complement(1063656..1064096) Brucella melitensis ATCC 23457 7677874 YP_002732809.1 CDS folE NC_012441.1 1064360 1065001 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1064360..1065001 Brucella melitensis ATCC 23457 7677875 YP_002732810.1 CDS BMEA_A1117 NC_012441.1 1065024 1065443 D PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1065024..1065443 Brucella melitensis ATCC 23457 7677876 YP_002732811.1 CDS BMEA_A1118 NC_012441.1 1065660 1066607 D patatin 1065660..1066607 Brucella melitensis ATCC 23457 7677877 YP_002732812.1 CDS BMEA_A1119 NC_012441.1 1066694 1066873 D hypothetical protein 1066694..1066873 Brucella melitensis ATCC 23457 7677878 YP_002732813.1 CDS BMEA_A1121 NC_012441.1 1067081 1068388 D site-specific recombinase, phage integrase family protein 1067081..1068388 Brucella melitensis ATCC 23457 7677880 YP_002732814.1 CDS BMEA_A1122 NC_012441.1 1068463 1068867 D hypothetical protein 1068463..1068867 Brucella melitensis ATCC 23457 7677881 YP_002732815.1 CDS BMEA_A1123 NC_012441.1 1070613 1072010 R hypothetical protein complement(1070613..1072010) Brucella melitensis ATCC 23457 7677882 YP_002732816.1 CDS BMEA_A1124 NC_012441.1 1072535 1073164 R DNA-invertase complement(1072535..1073164) Brucella melitensis ATCC 23457 7676931 YP_002732817.1 CDS BMEA_A1125 NC_012441.1 1073432 1073581 R hypothetical protein complement(1073432..1073581) Brucella melitensis ATCC 23457 7676202 YP_002732818.1 CDS BMEA_A1126 NC_012441.1 1073660 1073995 R hypothetical protein complement(1073660..1073995) Brucella melitensis ATCC 23457 7676203 YP_002732819.1 CDS BMEA_A1127 NC_012441.1 1074279 1074854 R BRO family protein complement(1074279..1074854) Brucella melitensis ATCC 23457 7676204 YP_002732820.1 CDS BMEA_A1129 NC_012441.1 1075381 1076526 R acyl-CoA transferase/carnitine dehydratase complement(1075381..1076526) Brucella melitensis ATCC 23457 7676206 YP_002732821.1 CDS BMEA_A1130 NC_012441.1 1076605 1077789 R glutaryl-CoA dehydrogenase complement(1076605..1077789) Brucella melitensis ATCC 23457 7676207 YP_002732822.1 CDS BMEA_A1132 NC_012441.1 1078792 1079775 R luciferase family protein complement(1078792..1079775) Brucella melitensis ATCC 23457 7676209 YP_002732823.1 CDS BMEA_A1133 NC_012441.1 1079856 1082945 R acriflavin resistance protein complement(1079856..1082945) Brucella melitensis ATCC 23457 7676210 YP_002732824.1 CDS BMEA_A1134 NC_012441.1 1082955 1084136 R RND family efflux transporter complement(1082955..1084136) Brucella melitensis ATCC 23457 7676211 YP_002732825.1 CDS BMEA_A1135 NC_012441.1 1084244 1084810 D TetR family transcriptional regulator 1084244..1084810 Brucella melitensis ATCC 23457 7676212 YP_002732826.1 CDS tgt NC_012441.1 1084847 1085980 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1084847..1085980) Brucella melitensis ATCC 23457 7676213 YP_002732827.1 CDS BMEA_A1137 NC_012441.1 1085977 1087068 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(1085977..1087068) Brucella melitensis ATCC 23457 7676214 YP_002732828.1 CDS BMEA_A1138 NC_012441.1 1087190 1087696 R cyclophilin type peptidyl-prolyl cis-trans isomerase complement(1087190..1087696) Brucella melitensis ATCC 23457 7676215 YP_002732829.1 CDS BMEA_A1139 NC_012441.1 1087759 1088349 R cyclophilin type peptidyl-prolyl cis-trans isomerase complement(1087759..1088349) Brucella melitensis ATCC 23457 7676216 YP_002732830.1 CDS coaD NC_012441.1 1088370 1088864 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1088370..1088864) Brucella melitensis ATCC 23457 7676217 YP_002732831.1 CDS BMEA_A1142 NC_012441.1 1089059 1089208 D hypothetical protein 1089059..1089208 Brucella melitensis ATCC 23457 7676218 YP_002732832.1 CDS BMEA_A1143 NC_012441.1 1089080 1089319 R hypothetical protein complement(1089080..1089319) Brucella melitensis ATCC 23457 7676219 YP_002732833.1 CDS gyrA NC_012441.1 1089375 1092143 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1089375..1092143) Brucella melitensis ATCC 23457 7676220 YP_002732834.1 CDS BMEA_A1145 NC_012441.1 1092431 1093060 D hypothetical protein 1092431..1093060 Brucella melitensis ATCC 23457 7676221 YP_002732835.1 CDS phnN NC_012441.1 1093151 1093729 R phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN complement(1093151..1093729) Brucella melitensis ATCC 23457 7676222 YP_002732836.1 CDS phnF NC_012441.1 1093916 1094677 D phosphonates metabolism transcriptional regulator PhnF 1093916..1094677 Brucella melitensis ATCC 23457 7676223 YP_002732837.1 CDS ssb NC_012441.1 1095363 1095869 R single-strand binding protein complement(1095363..1095869) Brucella melitensis ATCC 23457 7676224 YP_002732838.1 CDS BMEA_A1149 NC_012441.1 1096437 1096637 D hypothetical protein 1096437..1096637 Brucella melitensis ATCC 23457 7676225 YP_002732839.1 CDS uvrA NC_012441.1 1096768 1099692 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1096768..1099692 Brucella melitensis ATCC 23457 7676226 YP_002732840.1 CDS BMEA_A1151 NC_012441.1 1099879 1100154 R DNA-binding protein HRL18 complement(1099879..1100154) Brucella melitensis ATCC 23457 7676227 YP_002732841.1 CDS lon NC_012441.1 1100335 1102773 R ATP-dependent protease La complement(1100335..1102773) Brucella melitensis ATCC 23457 7676228 YP_002732842.1 CDS clpX NC_012441.1 1103205 1104479 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1103205..1104479) Brucella melitensis ATCC 23457 7676229 YP_002732843.1 CDS BMEA_A1154 NC_012441.1 1104861 1105490 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1104861..1105490) Brucella melitensis ATCC 23457 7676230 YP_002732844.1 CDS hflX NC_012441.1 1105595 1107013 R GTP-binding proten HflX complement(1105595..1107013) Brucella melitensis ATCC 23457 7676231 YP_002732845.1 CDS hfq NC_012441.1 1107204 1107440 R Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq complement(1107204..1107440) Brucella melitensis ATCC 23457 7676232 YP_002732846.1 CDS BMEA_A1157 NC_012441.1 1107446 1107685 R hypothetical protein complement(1107446..1107685) Brucella melitensis ATCC 23457 7676233 YP_002732847.1 CDS BMEA_A1158 NC_012441.1 1107669 1108499 R hypothetical protein complement(1107669..1108499) Brucella melitensis ATCC 23457 7676234 YP_002732848.1 CDS BMEA_A1159 NC_012441.1 1108548 1109924 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(1108548..1109924) Brucella melitensis ATCC 23457 7676235 YP_002732849.1 CDS BMEA_A1160 NC_012441.1 1109949 1111310 R nitrogen assimilation regulatory protein complement(1109949..1111310) Brucella melitensis ATCC 23457 7676236 YP_002732850.1 CDS BMEA_A1161 NC_012441.1 1111312 1113636 R PAS domain S-box-containing protein complement(1111312..1113636) Brucella melitensis ATCC 23457 7676237 YP_002732851.1 CDS ntrC NC_012441.1 1113727 1115202 R nitrogen regulation protein NR(I) complement(1113727..1115202) Brucella melitensis ATCC 23457 7676238 YP_002732852.1 CDS BMEA_A1163 NC_012441.1 1115199 1116341 R nitrogen regulation protein ntrB complement(1115199..1116341) Brucella melitensis ATCC 23457 7676239 YP_002732853.1 CDS BMEA_A1164 NC_012441.1 1116341 1117342 R TIM-barrel protein nifR3 family protein complement(1116341..1117342) Brucella melitensis ATCC 23457 7676240 YP_002732854.1 CDS ispF NC_012441.1 1117354 1118709 D bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 1117354..1118709 Brucella melitensis ATCC 23457 7676241 YP_002732855.1 CDS BMEA_A1166 NC_012441.1 1118706 1119203 D CinA domain-containing protein 1118706..1119203 Brucella melitensis ATCC 23457 7676242 YP_002732856.1 CDS BMEA_A1168 NC_012441.1 1120080 1120538 R cyclase/dehydrase complement(1120080..1120538) Brucella melitensis ATCC 23457 7676244 YP_002732857.1 CDS lipA NC_012441.1 1120544 1121512 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1120544..1121512) Brucella melitensis ATCC 23457 7676245 YP_002732858.1 CDS BMEA_A1170 NC_012441.1 1121622 1121783 R hypothetical protein complement(1121622..1121783) Brucella melitensis ATCC 23457 7676246 YP_002732859.1 CDS lpdA NC_012441.1 1121902 1123365 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1121902..1123365) Brucella melitensis ATCC 23457 7676247 YP_002732860.1 CDS BMEA_A1172 NC_012441.1 1123448 1124791 R branched-chain alpha-keto acid dehydrogenase subunit E2 complement(1123448..1124791) Brucella melitensis ATCC 23457 7676248 YP_002732861.1 CDS BMEA_A1173 NC_012441.1 1124809 1126194 R catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta complement(1124809..1126194) Brucella melitensis ATCC 23457 7676249 YP_002732862.1 CDS pdhA NC_012441.1 1126213 1127253 R dehydrogenase E1 component complement(1126213..1127253) Brucella melitensis ATCC 23457 7676250 YP_002732863.1 CDS BMEA_A1175 NC_012441.1 1127392 1127721 R septum formation initiator complement(1127392..1127721) Brucella melitensis ATCC 23457 7676251 YP_002732864.1 CDS BMEA_A1176 NC_012441.1 1127993 1128574 R hypothetical protein complement(1127993..1128574) Brucella melitensis ATCC 23457 7676252 YP_002732865.1 CDS eno NC_012441.1 1128911 1130188 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1128911..1130188) Brucella melitensis ATCC 23457 7676253 YP_002732866.1 CDS kdsA NC_012441.1 1130375 1131208 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1130375..1131208) Brucella melitensis ATCC 23457 7676254 YP_002732867.1 CDS pyrG NC_012441.1 1131314 1132942 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1131314..1132942) Brucella melitensis ATCC 23457 7676255 YP_002732868.1 CDS BMEA_A1180 NC_012441.1 1133212 1133904 R ErfK/YbiS/YcfS/YnhG family protein complement(1133212..1133904) Brucella melitensis ATCC 23457 7676256 YP_002732869.1 CDS secG NC_012441.1 1134158 1134604 R preprotein translocase subunit SecG complement(1134158..1134604) Brucella melitensis ATCC 23457 7676257 YP_002732870.1 CDS tpiA NC_012441.1 1134704 1135468 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1134704..1135468) Brucella melitensis ATCC 23457 7676258 YP_002732871.1 CDS BMEA_A1183 NC_012441.1 1135687 1137573 D rotamase family protein 1135687..1137573 Brucella melitensis ATCC 23457 7676259 YP_002732872.1 CDS trpD NC_012441.1 1137588 1138607 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1137588..1138607 Brucella melitensis ATCC 23457 7676260 YP_002732873.1 CDS BMEA_A1185 NC_012441.1 1138624 1139430 D involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1138624..1139430 Brucella melitensis ATCC 23457 7676261 YP_002732874.1 CDS moaC NC_012441.1 1139427 1139924 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1139427..1139924 Brucella melitensis ATCC 23457 7676262 YP_002732875.1 CDS BMEA_A1187 NC_012441.1 1140020 1141234 D molybdenum cofactor synthesis domain-containing protein 1140020..1141234 Brucella melitensis ATCC 23457 7676263 YP_002732876.1 CDS lexA NC_012441.1 1141482 1142204 D Represses a number of genes involved in the response to DNA damage; LexA repressor 1141482..1142204 Brucella melitensis ATCC 23457 7676264 YP_002732877.1 CDS BMEA_A1190 NC_012441.1 1144760 1144936 R hypothetical protein complement(1144760..1144936) Brucella melitensis ATCC 23457 7676266 YP_002732878.1 CDS gltX NC_012441.1 1144949 1146370 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1144949..1146370 Brucella melitensis ATCC 23457 7676267 YP_002732879.1 CDS gltA NC_012441.1 1146599 1147891 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1146599..1147891 Brucella melitensis ATCC 23457 7676268 YP_002732880.1 CDS lpxB NC_012441.1 1148064 1149251 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(1148064..1149251) Brucella melitensis ATCC 23457 7676269 YP_002732881.1 CDS BMEA_A1194 NC_012441.1 1149248 1150150 R hypothetical protein complement(1149248..1150150) Brucella melitensis ATCC 23457 7676270 YP_002732882.1 CDS lpxA NC_012441.1 1150131 1150967 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1150131..1150967) Brucella melitensis ATCC 23457 7676271 YP_002732883.1 CDS fabZ NC_012441.1 1150976 1151449 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1150976..1151449) Brucella melitensis ATCC 23457 7676272 YP_002732884.1 CDS lpxD NC_012441.1 1151442 1152497 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1151442..1152497) Brucella melitensis ATCC 23457 7676273 YP_002732885.1 CDS yaeT NC_012441.1 1152551 1154896 R outer membrane protein assembly complex protein YaeT complement(1152551..1154896) Brucella melitensis ATCC 23457 7676274 YP_002732886.1 CDS BMEA_A1199 NC_012441.1 1155232 1156371 R membrane-associated zinc metalloprotease complement(1155232..1156371) Brucella melitensis ATCC 23457 7676275 YP_002732887.1 CDS BMEA_A1200 NC_012441.1 1156438 1157250 R phosphatidate cytidylyltransferase complement(1156438..1157250) Brucella melitensis ATCC 23457 7676276 YP_002732888.1 CDS uppS NC_012441.1 1157355 1158119 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(1157355..1158119) Brucella melitensis ATCC 23457 7676277 YP_002732889.1 CDS frr NC_012441.1 1158164 1158724 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1158164..1158724) Brucella melitensis ATCC 23457 7676278 YP_002732890.1 CDS pyrH NC_012441.1 1158760 1159731 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1158760..1159731) Brucella melitensis ATCC 23457 7676279 YP_002732891.1 CDS tsf NC_012441.1 1159649 1160566 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1159649..1160566) Brucella melitensis ATCC 23457 7676280 YP_002732892.1 CDS rpsB NC_012441.1 1160756 1161526 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1160756..1161526) Brucella melitensis ATCC 23457 7676932 YP_002732893.1 CDS BMEA_A1206 NC_012441.1 1161749 1162243 R hypothetical protein complement(1161749..1162243) Brucella melitensis ATCC 23457 7676933 YP_002732894.1 CDS BMEA_A1207 NC_012441.1 1162355 1163197 R hypothetical protein complement(1162355..1163197) Brucella melitensis ATCC 23457 7676934 YP_002732895.1 CDS BMEA_A1208 NC_012441.1 1163342 1163806 D endoribonuclease L-PSP 1163342..1163806 Brucella melitensis ATCC 23457 7677091 YP_002732896.1 CDS BMEA_A1209 NC_012441.1 1163808 1164548 D glycerophosphoryl diester phosphodiesterase 1163808..1164548 Brucella melitensis ATCC 23457 7677092 YP_002732897.1 CDS BMEA_A1210 NC_012441.1 1164603 1165790 D hypothetical protein 1164603..1165790 Brucella melitensis ATCC 23457 7677093 YP_002732898.1 CDS BMEA_A1211 NC_012441.1 1165862 1166284 D histidine triad protein 1165862..1166284 Brucella melitensis ATCC 23457 7677094 YP_002732899.1 CDS clpA NC_012441.1 1166391 1168865 R ATP-dependent Clp protease ATP-binding subunit ClpA complement(1166391..1168865) Brucella melitensis ATCC 23457 7677095 YP_002732900.1 CDS BMEA_A1213 NC_012441.1 1168872 1169222 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(1168872..1169222) Brucella melitensis ATCC 23457 7677096 YP_002732901.1 CDS BMEA_A1214 NC_012441.1 1169283 1169474 D hypothetical protein 1169283..1169474 Brucella melitensis ATCC 23457 7677097 YP_002732902.1 CDS BMEA_A1215 NC_012441.1 1169708 1171126 D serine-type D-Ala-D-Ala carboxypeptidase 1169708..1171126 Brucella melitensis ATCC 23457 7677098 YP_002732903.1 CDS BMEA_A1216 NC_012441.1 1171158 1171499 D hypothetical protein 1171158..1171499 Brucella melitensis ATCC 23457 7677099 YP_002732904.1 CDS BMEA_A1218 NC_012441.1 1171613 1172050 R hypothetical protein complement(1171613..1172050) Brucella melitensis ATCC 23457 7677100 YP_002732905.1 CDS sdaA NC_012441.1 1172139 1173542 R L-serine ammonia-lyase complement(1172139..1173542) Brucella melitensis ATCC 23457 7677101 YP_002732906.1 CDS BMEA_A1221 NC_012441.1 1173740 1173865 R hypothetical protein complement(1173740..1173865) Brucella melitensis ATCC 23457 7677102 YP_002732907.1 CDS BMEA_A1222 NC_012441.1 1174064 1174858 R hypothetical protein complement(1174064..1174858) Brucella melitensis ATCC 23457 7677103 YP_002732908.1 CDS BMEA_A1223 NC_012441.1 1176029 1176415 R MerR family transcriptional regulator complement(1176029..1176415) Brucella melitensis ATCC 23457 7677104 YP_002732909.1 CDS BMEA_A1224 NC_012441.1 1176653 1177018 D hypothetical protein 1176653..1177018 Brucella melitensis ATCC 23457 7677105 YP_002732910.1 CDS BMEA_A1225 NC_012441.1 1177033 1177380 D hypothetical protein 1177033..1177380 Brucella melitensis ATCC 23457 7677106 YP_002732911.1 CDS BMEA_A1226 NC_012441.1 1177451 1177765 D hypothetical protein 1177451..1177765 Brucella melitensis ATCC 23457 7677107 YP_002732912.1 CDS queF NC_012441.1 1178061 1178528 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1178061..1178528 Brucella melitensis ATCC 23457 7677108 YP_002732913.1 CDS BMEA_A1228 NC_012441.1 1178532 1178681 R hypothetical protein complement(1178532..1178681) Brucella melitensis ATCC 23457 7677109 YP_002732914.1 CDS BMEA_A1229 NC_012441.1 1178659 1178835 D hypothetical protein 1178659..1178835 Brucella melitensis ATCC 23457 7677110 YP_002732915.1 CDS BMEA_A1230 NC_012441.1 1178867 1179409 D hypothetical protein 1178867..1179409 Brucella melitensis ATCC 23457 7677111 YP_002732916.1 CDS BMEA_A1231 NC_012441.1 1179412 1180824 R hypothetical protein complement(1179412..1180824) Brucella melitensis ATCC 23457 7677112 YP_002732917.1 CDS BMEA_A1232 NC_012441.1 1181773 1182507 D propionyl-CoA carboxylase subunit beta 1181773..1182507 Brucella melitensis ATCC 23457 7677113 YP_002732918.1 CDS BMEA_A1233 NC_012441.1 1182592 1184595 D propionyl-coenzyme A carboxylase subunit alpha 1182592..1184595 Brucella melitensis ATCC 23457 7677114 YP_002732919.1 CDS BMEA_A1234 NC_012441.1 1184656 1186794 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1184656..1186794 Brucella melitensis ATCC 23457 7677115 YP_002732920.1 CDS BMEA_A1235 NC_012441.1 1186901 1187263 R hypothetical protein complement(1186901..1187263) Brucella melitensis ATCC 23457 7677116 YP_002732921.1 CDS BMEA_A1236 NC_012441.1 1187450 1189498 R TRAP transporter transmembrane protein complement(1187450..1189498) Brucella melitensis ATCC 23457 7677117 YP_002732922.1 CDS BMEA_A1237 NC_012441.1 1189539 1189685 R hypothetical protein complement(1189539..1189685) Brucella melitensis ATCC 23457 7677118 YP_002732923.1 CDS BMEA_A1238 NC_012441.1 1189735 1190724 R TRAP transporter solute receptor complement(1189735..1190724) Brucella melitensis ATCC 23457 7677119 YP_002732924.1 CDS murI NC_012441.1 1190870 1191703 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1190870..1191703) Brucella melitensis ATCC 23457 7677120 YP_002732925.1 CDS BMEA_A1240 NC_012441.1 1191700 1192530 R TrmH family RNA methyltransferase complement(1191700..1192530) Brucella melitensis ATCC 23457 7677121 YP_002732926.1 CDS BMEA_A1241 NC_012441.1 1192710 1193294 D Pfpi family intracellular protease 1192710..1193294 Brucella melitensis ATCC 23457 7677122 YP_002732927.1 CDS BMEA_A1242 NC_012441.1 1193383 1193793 D hypothetical protein 1193383..1193793 Brucella melitensis ATCC 23457 7677123 YP_002732928.1 CDS BMEA_A1243 NC_012441.1 1193921 1195135 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1193921..1195135 Brucella melitensis ATCC 23457 7677124 YP_002732929.1 CDS BMEA_A1244 NC_012441.1 1195357 1196802 D alkaline phosphatase 1195357..1196802 Brucella melitensis ATCC 23457 7677125 YP_002732930.1 CDS alaS NC_012441.1 1196954 1199611 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1196954..1199611) Brucella melitensis ATCC 23457 7677126 YP_002732931.1 CDS recA NC_012441.1 1200004 1201089 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1200004..1201089) Brucella melitensis ATCC 23457 7677127 YP_002732932.1 CDS BMEA_A1247 NC_012441.1 1201259 1201384 R hypothetical protein complement(1201259..1201384) Brucella melitensis ATCC 23457 7677128 YP_002732933.1 CDS BMEA_A1248 NC_012441.1 1201420 1202082 R OmpA/MotB domain-containing protein complement(1201420..1202082) Brucella melitensis ATCC 23457 7677129 YP_002732934.1 CDS BMEA_A1249 NC_012441.1 1202169 1202753 R lytic transglycosylase complement(1202169..1202753) Brucella melitensis ATCC 23457 7677130 YP_002732935.1 CDS BMEA_A1250 NC_012441.1 1202877 1204190 R recombination factor protein RarA complement(1202877..1204190) Brucella melitensis ATCC 23457 7677131 YP_002732936.1 CDS degP NC_012441.1 1204337 1205761 R protease Do complement(1204337..1205761) Brucella melitensis ATCC 23457 7677132 YP_002732937.1 CDS rplQ NC_012441.1 1206041 1206469 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1206041..1206469) Brucella melitensis ATCC 23457 7677133 YP_002732938.1 CDS rpoA NC_012441.1 1206631 1207644 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1206631..1207644) Brucella melitensis ATCC 23457 7677134 YP_002732939.1 CDS BMEA_A1254 NC_012441.1 1207760 1208149 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1207760..1208149) Brucella melitensis ATCC 23457 7677135 YP_002732940.1 CDS BMEA_A1255 NC_012441.1 1208277 1208645 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1208277..1208645) Brucella melitensis ATCC 23457 7677136 YP_002732941.1 CDS BMEA_A1256 NC_012441.1 1208639 1208812 D hypothetical protein 1208639..1208812 Brucella melitensis ATCC 23457 7677137 YP_002732942.1 CDS BMEA_A1257 NC_012441.1 1208955 1209539 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(1208955..1209539) Brucella melitensis ATCC 23457 7677138 YP_002732943.1 CDS secY NC_012441.1 1209536 1210876 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1209536..1210876) Brucella melitensis ATCC 23457 7677139 YP_002732944.1 CDS rplO NC_012441.1 1211037 1211507 R late assembly protein; 50S ribosomal protein L15 complement(1211037..1211507) Brucella melitensis ATCC 23457 7677140 YP_002732945.1 CDS rpmD NC_012441.1 1211528 1211725 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(1211528..1211725) Brucella melitensis ATCC 23457 7677141 YP_002732946.1 CDS rpsE NC_012441.1 1211843 1212403 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1211843..1212403) Brucella melitensis ATCC 23457 7677142 YP_002732947.1 CDS rplR NC_012441.1 1212445 1212807 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1212445..1212807) Brucella melitensis ATCC 23457 7677143 YP_002732948.1 CDS BMEA_A1263 NC_012441.1 1212820 1213353 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1212820..1213353) Brucella melitensis ATCC 23457 7677144 YP_002732949.1 CDS BMEA_A1264 NC_012441.1 1213392 1213790 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1213392..1213790) Brucella melitensis ATCC 23457 7677145 YP_002732950.1 CDS BMEA_A1265 NC_012441.1 1213801 1214106 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(1213801..1214106) Brucella melitensis ATCC 23457 7677146 YP_002732951.1 CDS BMEA_A1266 NC_012441.1 1214134 1214691 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1214134..1214691) Brucella melitensis ATCC 23457 7677147 YP_002732952.1 CDS rplX NC_012441.1 1214684 1214995 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1214684..1214995) Brucella melitensis ATCC 23457 7677148 YP_002732953.1 CDS rplN NC_012441.1 1215008 1215376 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1215008..1215376) Brucella melitensis ATCC 23457 7677149 YP_002732954.1 CDS BMEA_A1269 NC_012441.1 1215445 1215687 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1215445..1215687) Brucella melitensis ATCC 23457 7677150 YP_002732955.1 CDS rpmC NC_012441.1 1215700 1215900 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1215700..1215900) Brucella melitensis ATCC 23457 7677151 YP_002732956.1 CDS rplP NC_012441.1 1215913 1216326 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1215913..1216326) Brucella melitensis ATCC 23457 7677152 YP_002732957.1 CDS rpsC NC_012441.1 1216365 1217075 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1216365..1217075) Brucella melitensis ATCC 23457 7677153 YP_002732958.1 CDS rplV NC_012441.1 1217075 1217464 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1217075..1217464) Brucella melitensis ATCC 23457 7677154 YP_002732959.1 CDS rpsS NC_012441.1 1217467 1217745 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1217467..1217745) Brucella melitensis ATCC 23457 7677155 YP_002732960.1 CDS rplB NC_012441.1 1217761 1218594 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1217761..1218594) Brucella melitensis ATCC 23457 7677156 YP_002732961.1 CDS BMEA_A1276 NC_012441.1 1218616 1218909 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1218616..1218909) Brucella melitensis ATCC 23457 7677157 YP_002732962.1 CDS BMEA_A1277 NC_012441.1 1218906 1219526 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1218906..1219526) Brucella melitensis ATCC 23457 7677158 YP_002732963.1 CDS BMEA_A1278 NC_012441.1 1219526 1220239 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1219526..1220239) Brucella melitensis ATCC 23457 7677159 YP_002732964.1 CDS rpsJ NC_012441.1 1220269 1220577 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1220269..1220577) Brucella melitensis ATCC 23457 7677160 YP_002732965.1 CDS tuf NC_012441.1 1220638 1221813 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1220638..1221813) Brucella melitensis ATCC 23457 7677161 YP_002732966.1 CDS fusA NC_012441.1 1221877 1223961 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1221877..1223961) Brucella melitensis ATCC 23457 7677162 YP_002732967.1 CDS rpsG NC_012441.1 1223992 1224462 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1223992..1224462) Brucella melitensis ATCC 23457 7677163 YP_002732968.1 CDS rpsL NC_012441.1 1224529 1224900 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1224529..1224900) Brucella melitensis ATCC 23457 7677164 YP_002732969.1 CDS BMEA_A1284 NC_012441.1 1224990 1225124 R hypothetical protein complement(1224990..1225124) Brucella melitensis ATCC 23457 7677165 YP_002732970.1 CDS BMEA_A1285 NC_012441.1 1225332 1225691 D hypothetical protein 1225332..1225691 Brucella melitensis ATCC 23457 7677166 YP_002732971.1 CDS rpoC NC_012441.1 1225798 1230000 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1225798..1230000) Brucella melitensis ATCC 23457 7677167 YP_002732972.1 CDS BMEA_A1287 NC_012441.1 1229997 1230122 R hypothetical protein complement(1229997..1230122) Brucella melitensis ATCC 23457 7677168 YP_002732973.1 CDS rpoB NC_012441.1 1230149 1234282 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1230149..1234282) Brucella melitensis ATCC 23457 7677169 YP_002732974.1 CDS rplL NC_012441.1 1234490 1234864 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1234490..1234864) Brucella melitensis ATCC 23457 7677639 YP_002732975.1 CDS BMEA_A1290 NC_012441.1 1234916 1235434 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1234916..1235434) Brucella melitensis ATCC 23457 7677018 YP_002732976.1 CDS rplA NC_012441.1 1235825 1236526 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1235825..1236526) Brucella melitensis ATCC 23457 7677019 YP_002732977.1 CDS rplK NC_012441.1 1236531 1236959 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1236531..1236959) Brucella melitensis ATCC 23457 7677020 YP_002732978.1 CDS nusG NC_012441.1 1237162 1237689 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1237162..1237689) Brucella melitensis ATCC 23457 7677021 YP_002732979.1 CDS secE NC_012441.1 1237713 1237913 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1237713..1237913) Brucella melitensis ATCC 23457 7677022 YP_002732980.1 CDS tuf NC_012441.1 1238587 1239762 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1238587..1239762) Brucella melitensis ATCC 23457 7677024 YP_002732981.1 CDS BMEA_A1297 NC_012441.1 1239713 1239913 D hypothetical protein 1239713..1239913 Brucella melitensis ATCC 23457 7677025 YP_002732982.1 CDS BMEA_A1300 NC_012441.1 1240393 1241253 D TrmH family RNA methyltransferase 1240393..1241253 Brucella melitensis ATCC 23457 7677028 YP_002732983.1 CDS BMEA_A1301 NC_012441.1 1241314 1241787 R hypothetical protein complement(1241314..1241787) Brucella melitensis ATCC 23457 7677029 YP_002732984.1 CDS BMEA_A1302 NC_012441.1 1241916 1242677 R rhomboid family protein complement(1241916..1242677) Brucella melitensis ATCC 23457 7677030 YP_002732985.1 CDS BMEA_A1303 NC_012441.1 1243036 1243677 D hypothetical protein 1243036..1243677 Brucella melitensis ATCC 23457 7677031 YP_002732986.1 CDS BMEA_A1304 NC_012441.1 1243921 1244526 D transglutaminase 1243921..1244526 Brucella melitensis ATCC 23457 7677032 YP_002732987.1 CDS BMEA_A1305 NC_012441.1 1244605 1245132 R hypothetical protein complement(1244605..1245132) Brucella melitensis ATCC 23457 7677033 YP_002732988.1 CDS BMEA_A1306 NC_012441.1 1245196 1245588 R IS4 transposase complement(1245196..1245588) Brucella melitensis ATCC 23457 7677034 YP_002732989.1 CDS BMEA_A1307 NC_012441.1 1245585 1245953 R transposase complement(1245585..1245953) Brucella melitensis ATCC 23457 7677035 YP_002732990.1 CDS BMEA_A1309 NC_012441.1 1246247 1246501 R hypothetical protein complement(1246247..1246501) Brucella melitensis ATCC 23457 7677036 YP_002732991.1 CDS cysE NC_012441.1 1246749 1247573 R serine O-acetyltransferase complement(1246749..1247573) Brucella melitensis ATCC 23457 7677037 YP_002732992.1 CDS BMEA_A1311 NC_012441.1 1247748 1248518 R alpha/beta hydrolase complement(1247748..1248518) Brucella melitensis ATCC 23457 7677038 YP_002732993.1 CDS BMEA_A1312 NC_012441.1 1248552 1249031 R hypothetical protein complement(1248552..1249031) Brucella melitensis ATCC 23457 7677039 YP_002732994.1 CDS BMEA_A1313 NC_012441.1 1249405 1249986 R cold shock-like protein CspG complement(1249405..1249986) Brucella melitensis ATCC 23457 7677040 YP_002732995.1 CDS BMEA_A1314 NC_012441.1 1250110 1250247 R hypothetical protein complement(1250110..1250247) Brucella melitensis ATCC 23457 7677041 YP_002732996.1 CDS BMEA_A1315 NC_012441.1 1250348 1251376 R import inner membrane translocase subunit Tim44 complement(1250348..1251376) Brucella melitensis ATCC 23457 7677042 YP_002732997.1 CDS recJ NC_012441.1 1251538 1253322 R single-stranded-DNA-specific exonuclease RecJ complement(1251538..1253322) Brucella melitensis ATCC 23457 7677043 YP_002732998.1 CDS BMEA_A1317 NC_012441.1 1253372 1254433 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1253372..1254433) Brucella melitensis ATCC 23457 7677044 YP_002732999.1 CDS BMEA_A1318 NC_012441.1 1254462 1254602 D hypothetical protein 1254462..1254602 Brucella melitensis ATCC 23457 7677045 YP_002733000.1 CDS glpX NC_012441.1 1254736 1255722 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(1254736..1255722) Brucella melitensis ATCC 23457 7677046 YP_002733001.1 CDS BMEA_A1320 NC_012441.1 1256115 1257434 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1256115..1257434) Brucella melitensis ATCC 23457 7677047 YP_002733002.1 CDS BMEA_A1321 NC_012441.1 1257570 1258790 R aminotransferase complement(1257570..1258790) Brucella melitensis ATCC 23457 7677048 YP_002733003.1 CDS BMEA_A1322 NC_012441.1 1258921 1259268 R hypothetical protein complement(1258921..1259268) Brucella melitensis ATCC 23457 7677049 YP_002733004.1 CDS BMEA_A1323 NC_012441.1 1259696 1259899 R hypothetical protein complement(1259696..1259899) Brucella melitensis ATCC 23457 7677050 YP_002733005.1 CDS BMEA_A1327 NC_012441.1 1261648 1261932 D hypothetical protein 1261648..1261932 Brucella melitensis ATCC 23457 7677054 YP_002733006.1 CDS sfsA NC_012441.1 1262255 1262971 D Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1262255..1262971 Brucella melitensis ATCC 23457 7677055 YP_002733007.1 CDS map NC_012441.1 1262971 1263798 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1262971..1263798 Brucella melitensis ATCC 23457 7677056 YP_002733008.1 CDS BMEA_A1330 NC_012441.1 1263854 1264603 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1263854..1264603 Brucella melitensis ATCC 23457 7677057 YP_002733009.1 CDS BMEA_A1331 NC_012441.1 1264805 1265443 D hypothetical protein 1264805..1265443 Brucella melitensis ATCC 23457 7677058 YP_002733010.1 CDS cbiE NC_012441.1 1265732 1266937 R precorrin-6y C5,15-methyltransferase subunit CbiE complement(1265732..1266937) Brucella melitensis ATCC 23457 7677059 YP_002733011.1 CDS cobG NC_012441.1 1267011 1268306 D precorrin-3B synthase 1267011..1268306 Brucella melitensis ATCC 23457 7677060 YP_002733012.1 CDS BMEA_A1334 NC_012441.1 1268316 1268942 D catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 1268316..1268942 Brucella melitensis ATCC 23457 7677061 YP_002733013.1 CDS cobI NC_012441.1 1268942 1269676 D catalyzes the formation of precorrin-3 from precorrin-2; precorrin-2 C(20)-methyltransferase 1268942..1269676 Brucella melitensis ATCC 23457 7677062 YP_002733014.1 CDS cobJ NC_012441.1 1269622 1271367 D precorrin-3B C(17)-methyltransferase 1269622..1271367 Brucella melitensis ATCC 23457 7677063 YP_002733015.1 CDS BMEA_A1337 NC_012441.1 1271405 1271890 R hypothetical protein complement(1271405..1271890) Brucella melitensis ATCC 23457 7677064 YP_002733016.1 CDS BMEA_A1339 NC_012441.1 1272915 1273436 R 4-hydroxyphenylacetate 3-monooxygenase reductase subunit complement(1272915..1273436) Brucella melitensis ATCC 23457 7677066 YP_002733017.1 CDS BMEA_A1340 NC_012441.1 1273485 1274672 D extracellular ligand-binding receptor 1273485..1274672 Brucella melitensis ATCC 23457 7677067 YP_002733018.1 CDS BMEA_A1341 NC_012441.1 1274658 1275641 R CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein complement(1274658..1275641) Brucella melitensis ATCC 23457 7677068 YP_002733019.1 CDS BMEA_A1342 NC_012441.1 1275678 1276676 R L-threonine-O-3-phosphate decarboxylase complement(1275678..1276676) Brucella melitensis ATCC 23457 7677069 YP_002733020.1 CDS cobB NC_012441.1 1276673 1277983 R responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase complement(1276673..1277983) Brucella melitensis ATCC 23457 7677070 YP_002733021.1 CDS cobA NC_012441.1 1277980 1278858 R uroporphyrin-III C-methyltransferase complement(1277980..1278858) Brucella melitensis ATCC 23457 7677071 YP_002733022.1 CDS cbiD NC_012441.1 1278919 1280028 D Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1278919..1280028 Brucella melitensis ATCC 23457 7677072 YP_002733023.1 CDS BMEA_A1346 NC_012441.1 1280015 1280761 D CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1280015..1280761 Brucella melitensis ATCC 23457 7677073 YP_002733024.1 CDS cobM NC_012441.1 1280750 1281508 R precorrin-4 C(11)-methyltransferase complement(1280750..1281508) Brucella melitensis ATCC 23457 7677074 YP_002733025.1 CDS BMEA_A1348 NC_012441.1 1281568 1281963 R protein CobE complement(1281568..1281963) Brucella melitensis ATCC 23457 7677075 YP_002733026.1 CDS BMEA_A1349 NC_012441.1 1281956 1282402 R hypothetical protein complement(1281956..1282402) Brucella melitensis ATCC 23457 7677076 YP_002733027.1 CDS BMEA_A1350 NC_012441.1 1282562 1283347 D hypothetical protein 1282562..1283347 Brucella melitensis ATCC 23457 7677077 YP_002733028.1 CDS BMEA_A1351 NC_012441.1 1283344 1283772 R hypothetical protein complement(1283344..1283772) Brucella melitensis ATCC 23457 7677078 YP_002733029.1 CDS cobO NC_012441.1 1283772 1284410 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1283772..1284410) Brucella melitensis ATCC 23457 7677079 YP_002733030.1 CDS cobN NC_012441.1 1284403 1288194 R with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN complement(1284403..1288194) Brucella melitensis ATCC 23457 7677080 YP_002733031.1 CDS cobW NC_012441.1 1288194 1289243 R cobalamin biosynthesis protein CobW complement(1288194..1289243) Brucella melitensis ATCC 23457 7677081 YP_002733032.1 CDS BMEA_A1355 NC_012441.1 1289247 1289768 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase complement(1289247..1289768) Brucella melitensis ATCC 23457 7677082 YP_002733033.1 CDS cbtA NC_012441.1 1289774 1290490 R cobalt transporter subunit CbtB complement(1289774..1290490) Brucella melitensis ATCC 23457 7677083 YP_002733034.1 CDS cbtB NC_012441.1 1290579 1290767 R cobalt transporter subunit CbtB complement(1290579..1290767) Brucella melitensis ATCC 23457 7677084 YP_002733035.1 CDS cobQ NC_012441.1 1291081 1292532 R catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase complement(1291081..1292532) Brucella melitensis ATCC 23457 7677085 YP_002733036.1 CDS BMEA_A1360 NC_012441.1 1292543 1292728 R hypothetical protein complement(1292543..1292728) Brucella melitensis ATCC 23457 7677086 YP_002733037.1 CDS BMEA_A1361 NC_012441.1 1292808 1293965 D acyl-CoA dehydrogenase 1292808..1293965 Brucella melitensis ATCC 23457 7677087 YP_002733038.1 CDS mmsB NC_012441.1 1293997 1294887 D 3-hydroxyisobutyrate dehydrogenase 1293997..1294887 Brucella melitensis ATCC 23457 7677088 YP_002733039.1 CDS BMEA_A1363 NC_012441.1 1295123 1295290 R hypothetical protein complement(1295123..1295290) Brucella melitensis ATCC 23457 7677089 YP_002733040.1 CDS BMEA_A1364 NC_012441.1 1295597 1296547 R HTH-type transcriptional regulator PecT complement(1295597..1296547) Brucella melitensis ATCC 23457 7677090 YP_002733041.1 CDS BMEA_A1365 NC_012441.1 1296963 1297961 D hypothetical protein 1296963..1297961 Brucella melitensis ATCC 23457 7676281 YP_002733042.1 CDS BMEA_A1367 NC_012441.1 1300875 1301165 R hypothetical protein complement(1300875..1301165) Brucella melitensis ATCC 23457 7676435 YP_002733043.1 CDS BMEA_A1368 NC_012441.1 1301272 1303854 R mechanosensitive ion channel protein MscS complement(1301272..1303854) Brucella melitensis ATCC 23457 7676436 YP_002733044.1 CDS BMEA_A1369 NC_012441.1 1303978 1304562 R hypothetical protein complement(1303978..1304562) Brucella melitensis ATCC 23457 7676437 YP_002733045.1 CDS secD NC_012441.1 1304614 1307151 D part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1304614..1307151 Brucella melitensis ATCC 23457 7676438 YP_002733046.1 CDS BMEA_A1371 NC_012441.1 1307229 1309088 D potassium efflux system protein 1307229..1309088 Brucella melitensis ATCC 23457 7676439 YP_002733047.1 CDS BMEA_A1372 NC_012441.1 1309088 1310059 D hypothetical protein 1309088..1310059 Brucella melitensis ATCC 23457 7676440 YP_002733048.1 CDS cysW NC_012441.1 1310937 1311767 R sulfate ABC transporter permease CysW complement(1310937..1311767) Brucella melitensis ATCC 23457 7676442 YP_002733049.1 CDS cysT NC_012441.1 1311754 1312620 R sulfate ABC transporter permease CysT complement(1311754..1312620) Brucella melitensis ATCC 23457 7676443 YP_002733050.1 CDS BMEA_A1376 NC_012441.1 1312747 1313751 R sulfate ABC transporter substrate-binding protein complement(1312747..1313751) Brucella melitensis ATCC 23457 7676444 YP_002733051.1 CDS BMEA_A1378 NC_012441.1 1314017 1314202 R hypothetical protein complement(1314017..1314202) Brucella melitensis ATCC 23457 7676445 YP_002733052.1 CDS BMEA_A1379 NC_012441.1 1314382 1315950 R integral membrane protein TerC complement(1314382..1315950) Brucella melitensis ATCC 23457 7676446 YP_002733053.1 CDS BMEA_A1380 NC_012441.1 1316368 1317030 R hypothetical protein complement(1316368..1317030) Brucella melitensis ATCC 23457 7676447 YP_002733054.1 CDS BMEA_A1381 NC_012441.1 1317020 1317133 D hypothetical protein 1317020..1317133 Brucella melitensis ATCC 23457 7676448 YP_002733055.1 CDS BMEA_A1384 NC_012441.1 1317927 1318466 D hypothetical protein 1317927..1318466 Brucella melitensis ATCC 23457 7676450 YP_002733056.1 CDS BMEA_A1385 NC_012441.1 1318600 1319022 R transporter complement(1318600..1319022) Brucella melitensis ATCC 23457 7676451 YP_002733057.1 CDS BMEA_A1386 NC_012441.1 1319116 1319925 R short chain dehydrogenase complement(1319116..1319925) Brucella melitensis ATCC 23457 7676452 YP_002733058.1 CDS BMEA_A1387 NC_012441.1 1319940 1320719 R hypothetical protein complement(1319940..1320719) Brucella melitensis ATCC 23457 7676453 YP_002733059.1 CDS BMEA_A1388 NC_012441.1 1320733 1321860 R monosaccharide-transporting ATPase complement(1320733..1321860) Brucella melitensis ATCC 23457 7676454 YP_002733060.1 CDS BMEA_A1389 NC_012441.1 1322147 1323076 R periplasmic binding protein/LacI transcriptional regulator complement(1322147..1323076) Brucella melitensis ATCC 23457 7676455 YP_002733061.1 CDS BMEA_A1390 NC_012441.1 1323455 1324570 D 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase 1323455..1324570 Brucella melitensis ATCC 23457 7676456 YP_002733062.1 CDS BMEA_A1391 NC_012441.1 1324567 1325343 R achromobactin transport ATP-binding protein cbrD complement(1324567..1325343) Brucella melitensis ATCC 23457 7676457 YP_002733063.1 CDS BMEA_A1392 NC_012441.1 1325340 1326341 R transport system permease complement(1325340..1326341) Brucella melitensis ATCC 23457 7676458 YP_002733064.1 CDS BMEA_A1393 NC_012441.1 1326334 1327173 R periplasmic binding protein complement(1326334..1327173) Brucella melitensis ATCC 23457 7676459 YP_002733065.1 CDS BMEA_A1394 NC_012441.1 1327187 1329049 R TonB-dependent receptor complement(1327187..1329049) Brucella melitensis ATCC 23457 7676460 YP_002733066.1 CDS BMEA_A1396 NC_012441.1 1329338 1329493 R hypothetical protein complement(1329338..1329493) Brucella melitensis ATCC 23457 7676461 YP_002733067.1 CDS BMEA_A1397 NC_012441.1 1329543 1330655 R ABC transporter complement(1329543..1330655) Brucella melitensis ATCC 23457 7676462 YP_002733068.1 CDS BMEA_A1399 NC_012441.1 1333423 1334490 R HlyD family secretion protein complement(1333423..1334490) Brucella melitensis ATCC 23457 7676464 YP_002733069.1 CDS BMEA_A1400 NC_012441.1 1334470 1334649 D hypothetical protein 1334470..1334649 Brucella melitensis ATCC 23457 7676465 YP_002733070.1 CDS BMEA_A1401 NC_012441.1 1335036 1336331 R hypothetical protein complement(1335036..1336331) Brucella melitensis ATCC 23457 7676466 YP_002733071.1 CDS BMEA_A1402 NC_012441.1 1336910 1337086 R hypothetical protein complement(1336910..1337086) Brucella melitensis ATCC 23457 7676467 YP_002733072.1 CDS ureA NC_012441.1 1337146 1337448 D UreA, with UreB and UreC, catalyzes the hydrolysis of urea to ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1337146..1337448 Brucella melitensis ATCC 23457 7676468 YP_002733073.1 CDS ureB NC_012441.1 1337445 1337978 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) does not seem to be involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo; urease subunit beta 1337445..1337978 Brucella melitensis ATCC 23457 7676469 YP_002733074.1 CDS ureC NC_012441.1 1338018 1339739 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1338018..1339739 Brucella melitensis ATCC 23457 7676470 YP_002733075.1 CDS BMEA_A1406 NC_012441.1 1339787 1340392 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1339787..1340392 Brucella melitensis ATCC 23457 7676471 YP_002733076.1 CDS BMEA_A1407 NC_012441.1 1340364 1341095 D urease accessory protein UreF 1340364..1341095 Brucella melitensis ATCC 23457 7676472 YP_002733077.1 CDS ureG NC_012441.1 1341111 1341749 D urease accessory protein UreG 1341111..1341749 Brucella melitensis ATCC 23457 7676473 YP_002733078.1 CDS BMEA_A1409 NC_012441.1 1341749 1342657 D urease accessory protein UreD 1341749..1342657 Brucella melitensis ATCC 23457 7676474 YP_002733079.1 CDS yut NC_012441.1 1342667 1343716 D urea transporter 1342667..1343716 Brucella melitensis ATCC 23457 7676475 YP_002733080.1 CDS BMEA_A1411 NC_012441.1 1343743 1344501 D cobalt ABC transporter periplasmic binding protein CbiN 1343743..1344501 Brucella melitensis ATCC 23457 7676476 YP_002733081.1 CDS BMEA_A1412 NC_012441.1 1344521 1345156 D catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1344521..1345156 Brucella melitensis ATCC 23457 7676477 YP_002733082.1 CDS BMEA_A1413 NC_012441.1 1345153 1345779 D CbiL protein 1345153..1345779 Brucella melitensis ATCC 23457 7676478 YP_002733083.1 CDS cbiQ NC_012441.1 1345776 1346540 D cobalt ABC transporter permease CbiQ 1345776..1346540 Brucella melitensis ATCC 23457 7676479 YP_002733084.1 CDS BMEA_A1415 NC_012441.1 1346537 1347256 D cobalt ABC transporter ATP-binding protein 1346537..1347256 Brucella melitensis ATCC 23457 7676480 YP_002733085.1 CDS BMEA_A1416 NC_012441.1 1347277 1348089 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1347277..1348089) Brucella melitensis ATCC 23457 7676481 YP_002733086.1 CDS crcB NC_012441.1 1348102 1348491 R CrcB protein complement(1348102..1348491) Brucella melitensis ATCC 23457 7676482 YP_002733087.1 CDS BMEA_A1418 NC_012441.1 1348760 1349776 D hypothetical protein 1348760..1349776 Brucella melitensis ATCC 23457 7676483 YP_002733088.1 CDS BMEA_A1419 NC_012441.1 1349909 1350343 R pyridoxamine 5'-phosphate oxidase-like FMN-binding protein complement(1349909..1350343) Brucella melitensis ATCC 23457 7676484 YP_002733089.1 CDS BMEA_A1420 NC_012441.1 1350345 1350482 D hypothetical protein 1350345..1350482 Brucella melitensis ATCC 23457 7676485 YP_002733090.1 CDS BMEA_A1421 NC_012441.1 1350495 1351421 R phenazine biosynthesis protein PhzF family protein complement(1350495..1351421) Brucella melitensis ATCC 23457 7676486 YP_002733091.1 CDS BMEA_A1422 NC_012441.1 1351526 1352257 R NUDIX hydrolase complement(1351526..1352257) Brucella melitensis ATCC 23457 7676487 YP_002733092.1 CDS BMEA_A1423 NC_012441.1 1352277 1353386 R endonuclease/exonuclease/phosphatase complement(1352277..1353386) Brucella melitensis ATCC 23457 7676488 YP_002733093.1 CDS BMEA_A1424 NC_012441.1 1353463 1353978 D BA14K family protein 1353463..1353978 Brucella melitensis ATCC 23457 7676489 YP_002733094.1 CDS BMEA_A1425 NC_012441.1 1354025 1355257 R GntR family transcriptional regulator complement(1354025..1355257) Brucella melitensis ATCC 23457 7676490 YP_002733095.1 CDS BMEA_A1426 NC_012441.1 1355390 1355671 R hypothetical protein complement(1355390..1355671) Brucella melitensis ATCC 23457 7676491 YP_002733096.1 CDS ilvC NC_012441.1 1355693 1356712 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(1355693..1356712) Brucella melitensis ATCC 23457 7676492 YP_002733097.1 CDS BMEA_A1428 NC_012441.1 1356768 1357409 R TetR family transcriptional regulator complement(1356768..1357409) Brucella melitensis ATCC 23457 7676493 YP_002733098.1 CDS BMEA_A1429 NC_012441.1 1357467 1357622 D hypothetical protein 1357467..1357622 Brucella melitensis ATCC 23457 7676494 YP_002733099.1 CDS BMEA_A1430 NC_012441.1 1357619 1359574 R potassium transport system protein kup complement(1357619..1359574) Brucella melitensis ATCC 23457 7676495 YP_002733100.1 CDS BMEA_A1431 NC_012441.1 1359717 1359875 R hypothetical protein complement(1359717..1359875) Brucella melitensis ATCC 23457 7676496 YP_002733101.1 CDS BMEA_A1432 NC_012441.1 1359944 1360684 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(1359944..1360684) Brucella melitensis ATCC 23457 7676497 YP_002733102.1 CDS BMEA_A1433 NC_012441.1 1360981 1361382 D hypothetical protein 1360981..1361382 Brucella melitensis ATCC 23457 7676498 YP_002733103.1 CDS BMEA_A1434 NC_012441.1 1361383 1362549 R hypothetical protein complement(1361383..1362549) Brucella melitensis ATCC 23457 7676499 YP_002733104.1 CDS ilvN NC_012441.1 1362688 1363260 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1362688..1363260) Brucella melitensis ATCC 23457 7676500 YP_002733105.1 CDS ilvB NC_012441.1 1363279 1365102 R acetolactate synthase 3 catalytic subunit complement(1363279..1365102) Brucella melitensis ATCC 23457 7676501 YP_002733106.1 CDS miaA NC_012441.1 1365350 1366282 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1365350..1366282) Brucella melitensis ATCC 23457 7676502 YP_002733107.1 CDS serB NC_012441.1 1366300 1367199 D phosphoserine phosphatase SerB 1366300..1367199 Brucella melitensis ATCC 23457 7676503 YP_002733108.1 CDS BMEA_A1440 NC_012441.1 1368397 1368540 R hypothetical protein complement(1368397..1368540) Brucella melitensis ATCC 23457 7676505 YP_002733109.1 CDS degP NC_012441.1 1368551 1370125 R protease Do complement(1368551..1370125) Brucella melitensis ATCC 23457 7676506 YP_002733110.1 CDS BMEA_A1442 NC_012441.1 1370349 1370534 R hypothetical protein complement(1370349..1370534) Brucella melitensis ATCC 23457 7676507 YP_002733111.1 CDS hflC NC_012441.1 1370554 1371456 R HflC protein complement(1370554..1371456) Brucella melitensis ATCC 23457 7676508 YP_002733112.1 CDS hflK NC_012441.1 1371456 1372658 R HflK protein complement(1371456..1372658) Brucella melitensis ATCC 23457 7676509 YP_002733113.1 CDS BMEA_A1445 NC_012441.1 1372735 1373253 R dihydrofolate reductase type 3 complement(1372735..1373253) Brucella melitensis ATCC 23457 7676510 YP_002733114.1 CDS thyA NC_012441.1 1373256 1374050 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1373256..1374050) Brucella melitensis ATCC 23457 7676511 YP_002733115.1 CDS BMEA_A1447 NC_012441.1 1374151 1374462 R hypothetical protein complement(1374151..1374462) Brucella melitensis ATCC 23457 7676512 YP_002733117.1 CDS BMEA_A1450 NC_012441.1 1376249 1376395 R hypothetical protein complement(1376249..1376395) Brucella melitensis ATCC 23457 7676663 YP_002733118.1 CDS BMEA_A1451 NC_012441.1 1376626 1377252 D TetR family transcriptional regulator 1376626..1377252 Brucella melitensis ATCC 23457 7678146 YP_002733119.1 CDS BMEA_A1452 NC_012441.1 1377333 1377902 D hypothetical protein 1377333..1377902 Brucella melitensis ATCC 23457 7678147 YP_002733120.1 CDS BMEA_A1453 NC_012441.1 1378015 1378191 D hypothetical protein 1378015..1378191 Brucella melitensis ATCC 23457 7678148 YP_002733121.1 CDS BMEA_A1454 NC_012441.1 1378283 1378483 D hypothetical protein 1378283..1378483 Brucella melitensis ATCC 23457 7678149 YP_002733122.1 CDS BMEA_A1455 NC_012441.1 1378480 1378731 D hypothetical protein 1378480..1378731 Brucella melitensis ATCC 23457 7678150 YP_002733123.1 CDS BMEA_A1456 NC_012441.1 1378759 1382502 R AsmA family protein complement(1378759..1382502) Brucella melitensis ATCC 23457 7678151 YP_002733124.1 CDS BMEA_A1457 NC_012441.1 1382557 1382697 R hypothetical protein complement(1382557..1382697) Brucella melitensis ATCC 23457 7678152 YP_002733125.1 CDS BMEA_A1458 NC_012441.1 1382694 1384100 R hypothetical protein complement(1382694..1384100) Brucella melitensis ATCC 23457 7678153 YP_002733126.1 CDS BMEA_A1459 NC_012441.1 1384125 1384634 R hypothetical protein complement(1384125..1384634) Brucella melitensis ATCC 23457 7678154 YP_002733127.1 CDS BMEA_A1460 NC_012441.1 1384754 1385830 D serine/threonine protein kinase 1384754..1385830 Brucella melitensis ATCC 23457 7678155 YP_002733128.1 CDS BMEA_A1461 NC_012441.1 1385889 1388465 D ATP-dependent DNA helicase PcrA 1385889..1388465 Brucella melitensis ATCC 23457 7678156 YP_002733129.1 CDS BMEA_A1462 NC_012441.1 1388539 1389036 R CreA family protein complement(1388539..1389036) Brucella melitensis ATCC 23457 7678157 YP_002733130.1 CDS BMEA_A1463 NC_012441.1 1389101 1389790 R phosphonate metabolism protein complement(1389101..1389790) Brucella melitensis ATCC 23457 7678158 YP_002733131.1 CDS BMEA_A1464 NC_012441.1 1389899 1390489 D electron transport protein SCO1/SenC 1389899..1390489 Brucella melitensis ATCC 23457 7678159 YP_002733132.1 CDS BMEA_A1465 NC_012441.1 1390527 1391384 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1390527..1391384 Brucella melitensis ATCC 23457 7678160 YP_002733133.1 CDS BMEA_A1466 NC_012441.1 1391461 1393287 D peptidase M24 1391461..1393287 Brucella melitensis ATCC 23457 7678161 YP_002733134.1 CDS BMEA_A1467 NC_012441.1 1393288 1393992 R hypothetical protein complement(1393288..1393992) Brucella melitensis ATCC 23457 7678162 YP_002733135.1 CDS ligA NC_012441.1 1393992 1396151 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1393992..1396151) Brucella melitensis ATCC 23457 7678163 YP_002733136.1 CDS recN NC_012441.1 1396337 1398016 R DNA repair protein RecN complement(1396337..1398016) Brucella melitensis ATCC 23457 7678164 YP_002733137.1 CDS yfiO NC_012441.1 1398029 1398892 R outer membrane assembly lipoprotein YfiO complement(1398029..1398892) Brucella melitensis ATCC 23457 7678165 YP_002733138.1 CDS BMEA_A1471 NC_012441.1 1398994 1399239 D hypothetical protein 1398994..1399239 Brucella melitensis ATCC 23457 7678166 YP_002733139.1 CDS lpxC NC_012441.1 1399299 1400159 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(1399299..1400159) Brucella melitensis ATCC 23457 7678167 YP_002733140.1 CDS ftsZ NC_012441.1 1400699 1402399 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1400699..1402399) Brucella melitensis ATCC 23457 7678168 YP_002733141.1 CDS ftsA NC_012441.1 1402496 1403818 R cell division protein FtsA complement(1402496..1403818) Brucella melitensis ATCC 23457 7678169 YP_002733142.1 CDS BMEA_A1475 NC_012441.1 1403815 1404681 R cell division protein FtsQ complement(1403815..1404681) Brucella melitensis ATCC 23457 7678170 YP_002733143.1 CDS BMEA_A1476 NC_012441.1 1404738 1405664 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase complement(1404738..1405664) Brucella melitensis ATCC 23457 7678171 YP_002733144.1 CDS murB NC_012441.1 1405907 1406875 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1405907..1406875) Brucella melitensis ATCC 23457 7678172 YP_002733145.1 CDS murC NC_012441.1 1406875 1408290 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1406875..1408290) Brucella melitensis ATCC 23457 7678173 YP_002733146.1 CDS murG NC_012441.1 1408287 1409426 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase complement(1408287..1409426) Brucella melitensis ATCC 23457 7678174 YP_002733147.1 CDS ftsW NC_012441.1 1409653 1410810 R cell division protein FtsW complement(1409653..1410810) Brucella melitensis ATCC 23457 7678175 YP_002733148.1 CDS murD NC_012441.1 1410810 1412213 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(1410810..1412213) Brucella melitensis ATCC 23457 7678176 YP_002733149.1 CDS mraY NC_012441.1 1412226 1413308 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1412226..1413308) Brucella melitensis ATCC 23457 7678177 YP_002733150.1 CDS murF NC_012441.1 1413335 1414780 R UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(1413335..1414780) Brucella melitensis ATCC 23457 7678178 YP_002733151.1 CDS murE NC_012441.1 1414777 1416243 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(1414777..1416243) Brucella melitensis ATCC 23457 7678179 YP_002733152.1 CDS BMEA_A1485 NC_012441.1 1416304 1418127 R penicillin-binding protein 2 complement(1416304..1418127) Brucella melitensis ATCC 23457 7678180 YP_002733153.1 CDS BMEA_A1486 NC_012441.1 1418118 1418531 R hypothetical protein complement(1418118..1418531) Brucella melitensis ATCC 23457 7678181 YP_002733154.1 CDS mraW NC_012441.1 1418536 1419576 R S-adenosyl-methyltransferase MraW complement(1418536..1419576) Brucella melitensis ATCC 23457 7678182 YP_002733155.1 CDS BMEA_A1488 NC_012441.1 1419554 1419823 D hypothetical protein 1419554..1419823 Brucella melitensis ATCC 23457 7678183 YP_002733156.1 CDS BMEA_A1489 NC_012441.1 1420018 1421388 D manganese transport protein MntH 1420018..1421388 Brucella melitensis ATCC 23457 7678184 YP_002733157.1 CDS BMEA_A1493 NC_012441.1 1422090 1422734 R lytic transglycosylase complement(1422090..1422734) Brucella melitensis ATCC 23457 7678186 YP_002733158.1 CDS BMEA_A1494 NC_012441.1 1423075 1423881 R N-acetylmuramoyl-L-alanine amidase family 2 protein complement(1423075..1423881) Brucella melitensis ATCC 23457 7678187 YP_002733159.1 CDS BMEA_A1495 NC_012441.1 1423878 1424588 R DnaJ-like protein djlA complement(1423878..1424588) Brucella melitensis ATCC 23457 7678188 YP_002733160.1 CDS BMEA_A1496 NC_012441.1 1424708 1425112 R hypothetical protein complement(1424708..1425112) Brucella melitensis ATCC 23457 7678189 YP_002733161.1 CDS BMEA_A1497 NC_012441.1 1425416 1426249 D family 25 glycosyl hydrolase 1425416..1426249 Brucella melitensis ATCC 23457 7678190 YP_002733162.1 CDS BMEA_A1498 NC_012441.1 1426361 1427602 D lytic murein transglycosylase 1426361..1427602 Brucella melitensis ATCC 23457 7678191 YP_002733163.1 CDS BMEA_A1499 NC_012441.1 1427664 1428599 D auxin efflux carrier protein 1427664..1428599 Brucella melitensis ATCC 23457 7678192 YP_002733164.1 CDS metF NC_012441.1 1429034 1429945 R 5,10-methylenetetrahydrofolate reductase complement(1429034..1429945) Brucella melitensis ATCC 23457 7678193 YP_002733165.1 CDS BMEA_A1501 NC_012441.1 1429991 1431016 R methyltransferase type 11 complement(1429991..1431016) Brucella melitensis ATCC 23457 7678194 YP_002733166.1 CDS BMEA_A1502 NC_012441.1 1431136 1431459 D hypothetical protein 1431136..1431459 Brucella melitensis ATCC 23457 7678195 YP_002733167.1 CDS cit NC_012441.1 1431514 1432839 R metabolite:proton symporter family protein complement(1431514..1432839) Brucella melitensis ATCC 23457 7678196 YP_002733168.1 CDS BMEA_A1504 NC_012441.1 1432847 1433101 D hypothetical protein 1432847..1433101 Brucella melitensis ATCC 23457 7678197 YP_002733169.1 CDS BMEA_A1505 NC_012441.1 1433275 1433940 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(1433275..1433940) Brucella melitensis ATCC 23457 7678198 YP_002733170.1 CDS BMEA_A1506 NC_012441.1 1434114 1435763 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(1434114..1435763) Brucella melitensis ATCC 23457 7678199 YP_002733171.1 CDS BMEA_A1507 NC_012441.1 1435843 1436022 R hypothetical protein complement(1435843..1436022) Brucella melitensis ATCC 23457 7678200 YP_002733172.1 CDS BMEA_A1508 NC_012441.1 1436259 1437203 D lysophospholipase L2 1436259..1437203 Brucella melitensis ATCC 23457 7678201 YP_002733173.1 CDS BMEA_A1510 NC_012441.1 1438000 1438686 R hypothetical protein complement(1438000..1438686) Brucella melitensis ATCC 23457 7678203 YP_002733174.1 CDS BMEA_A1511 NC_012441.1 1439037 1440284 D biphenyl dioxygenase subunit alpha 1439037..1440284 Brucella melitensis ATCC 23457 7678204 YP_002733175.1 CDS BMEA_A1512 NC_012441.1 1440318 1441436 D ferredoxin 1440318..1441436 Brucella melitensis ATCC 23457 7678205 YP_002733176.1 CDS BMEA_A1513 NC_012441.1 1441439 1441660 R PhnA protein complement(1441439..1441660) Brucella melitensis ATCC 23457 7678206 YP_002733177.1 CDS BMEA_A1514 NC_012441.1 1441798 1442427 D nicotinamidase 1441798..1442427 Brucella melitensis ATCC 23457 7678207 YP_002733178.1 CDS BMEA_A1515 NC_012441.1 1442424 1443485 R hypothetical protein complement(1442424..1443485) Brucella melitensis ATCC 23457 7678208 YP_002733179.1 CDS BMEA_A1516 NC_012441.1 1443832 1444098 D hypothetical protein 1443832..1444098 Brucella melitensis ATCC 23457 7678209 YP_002733180.1 CDS BMEA_A1517 NC_012441.1 1444054 1444233 R hypothetical protein complement(1444054..1444233) Brucella melitensis ATCC 23457 7678210 YP_002733181.1 CDS BMEA_A1518 NC_012441.1 1444296 1445399 R penicillin acylase complement(1444296..1445399) Brucella melitensis ATCC 23457 7678211 YP_002733182.1 CDS BMEA_A1519 NC_012441.1 1445675 1446478 D hypothetical protein 1445675..1446478 Brucella melitensis ATCC 23457 7678212 YP_002733183.1 CDS BMEA_A1520 NC_012441.1 1446682 1446801 R hypothetical protein complement(1446682..1446801) Brucella melitensis ATCC 23457 7678213 YP_002733184.1 CDS BMEA_A1521 NC_012441.1 1447085 1447270 D hypothetical protein 1447085..1447270 Brucella melitensis ATCC 23457 7678214 YP_002733185.1 CDS BMEA_A1522 NC_012441.1 1447324 1447551 R hypothetical protein complement(1447324..1447551) Brucella melitensis ATCC 23457 7678215 YP_002733186.1 CDS BMEA_A1523 NC_012441.1 1447678 1448031 D hypothetical protein 1447678..1448031 Brucella melitensis ATCC 23457 7678216 YP_002733187.1 CDS BMEA_A1524 NC_012441.1 1448192 1448764 R hypothetical protein complement(1448192..1448764) Brucella melitensis ATCC 23457 7678217 YP_002733188.1 CDS BMEA_A1525 NC_012441.1 1449000 1449494 D phage integrase 1449000..1449494 Brucella melitensis ATCC 23457 7678218 YP_002733189.1 CDS BMEA_A1527 NC_012441.1 1449912 1450664 D hypothetical protein 1449912..1450664 Brucella melitensis ATCC 23457 7678220 YP_002733190.1 CDS BMEA_A1528 NC_012441.1 1450838 1451182 R hypothetical protein complement(1450838..1451182) Brucella melitensis ATCC 23457 7678221 YP_002733191.1 CDS BMEA_A1529 NC_012441.1 1451426 1451884 R hypothetical protein complement(1451426..1451884) Brucella melitensis ATCC 23457 7678222 YP_002733192.1 CDS BMEA_A1530 NC_012441.1 1452076 1452366 R hypothetical protein complement(1452076..1452366) Brucella melitensis ATCC 23457 7678223 YP_002733193.1 CDS rpoD NC_012441.1 1452390 1454408 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(1452390..1454408) Brucella melitensis ATCC 23457 7678224 YP_002733194.1 CDS BMEA_A1532 NC_012441.1 1454439 1454594 R hypothetical protein complement(1454439..1454594) Brucella melitensis ATCC 23457 7678225 YP_002733195.1 CDS dnaG NC_012441.1 1454876 1456843 R synthesizes RNA primers at the replication forks; DNA primase complement(1454876..1456843) Brucella melitensis ATCC 23457 7678226 YP_002733196.1 CDS BMEA_A1534 NC_012441.1 1457213 1458889 D Na+ cotransporter 1457213..1458889 Brucella melitensis ATCC 23457 7678308 YP_002733197.1 CDS BMEA_A1535 NC_012441.1 1458956 1459408 R GatB/Yqey domain-containing protein complement(1458956..1459408) Brucella melitensis ATCC 23457 7677170 YP_002733198.1 CDS carA NC_012441.1 1459788 1461011 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1459788..1461011 Brucella melitensis ATCC 23457 7677171 YP_002733199.1 CDS BMEA_A1538 NC_012441.1 1461183 1462109 R hypothetical protein complement(1461183..1462109) Brucella melitensis ATCC 23457 7677172 YP_002733200.1 CDS BMEA_A1539 NC_012441.1 1462226 1462744 R hypothetical protein complement(1462226..1462744) Brucella melitensis ATCC 23457 7677173 YP_002733201.1 CDS BMEA_A1540 NC_012441.1 1462830 1463534 D response regulator receiver protein 1462830..1463534 Brucella melitensis ATCC 23457 7677174 YP_002733202.1 CDS carB NC_012441.1 1463864 1467352 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1463864..1467352 Brucella melitensis ATCC 23457 7677175 YP_002733203.1 CDS BMEA_A1542 NC_012441.1 1467673 1468011 D hypothetical protein 1467673..1468011 Brucella melitensis ATCC 23457 7677176 YP_002733204.1 CDS BMEA_A1543 NC_012441.1 1468069 1469934 R ABC transporter complement(1468069..1469934) Brucella melitensis ATCC 23457 7677177 YP_002733205.1 CDS BMEA_A1544 NC_012441.1 1470124 1470585 D NUDIX hydrolase 1470124..1470585 Brucella melitensis ATCC 23457 7677178 YP_002733206.1 CDS BMEA_A1545 NC_012441.1 1470778 1470987 D hypothetical protein 1470778..1470987 Brucella melitensis ATCC 23457 7677179 YP_002733207.1 CDS BMEA_A1546 NC_012441.1 1471116 1471727 R protein GstA complement(1471116..1471727) Brucella melitensis ATCC 23457 7677180 YP_002733208.1 CDS BMEA_A1547 NC_012441.1 1471977 1473179 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1471977..1473179 Brucella melitensis ATCC 23457 7677181 YP_002733209.1 CDS BMEA_A1548 NC_012441.1 1473381 1473596 D hypothetical protein 1473381..1473596 Brucella melitensis ATCC 23457 7677182 YP_002733210.1 CDS BMEA_A1549 NC_012441.1 1473648 1474553 R hypothetical protein complement(1473648..1474553) Brucella melitensis ATCC 23457 7677183 YP_002733211.1 CDS trxB NC_012441.1 1474624 1475598 R thioredoxin-disulfide reductase complement(1474624..1475598) Brucella melitensis ATCC 23457 7677184 YP_002733212.1 CDS BMEA_A1551 NC_012441.1 1475920 1477320 D cation transporter 1475920..1477320 Brucella melitensis ATCC 23457 7677185 YP_002733213.1 CDS BMEA_A1552 NC_012441.1 1477327 1477491 D hypothetical protein 1477327..1477491 Brucella melitensis ATCC 23457 7677186 YP_002733214.1 CDS BMEA_A1553 NC_012441.1 1477578 1478048 D leucine-responsive regulatory protein 1477578..1478048 Brucella melitensis ATCC 23457 7677187 YP_002733215.1 CDS BMEA_A1554 NC_012441.1 1478055 1479119 R lipopolysaccharide core biosynthesis mannosyltransferase lpcC complement(1478055..1479119) Brucella melitensis ATCC 23457 7677188 YP_002733216.1 CDS greA NC_012441.1 1479126 1479599 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1479126..1479599) Brucella melitensis ATCC 23457 7677189 YP_002733217.1 CDS BMEA_A1556 NC_012441.1 1479868 1480923 R hypothetical protein complement(1479868..1480923) Brucella melitensis ATCC 23457 7677190 YP_002733218.1 CDS BMEA_A1557 NC_012441.1 1480913 1481101 R hypothetical protein complement(1480913..1481101) Brucella melitensis ATCC 23457 7677191 YP_002733219.1 CDS BMEA_A1558 NC_012441.1 1481079 1481990 D hypothetical protein 1481079..1481990 Brucella melitensis ATCC 23457 7677192 YP_002733220.1 CDS BMEA_A1559 NC_012441.1 1481995 1482345 R hypothetical protein complement(1481995..1482345) Brucella melitensis ATCC 23457 7677193 YP_002733221.1 CDS BMEA_A1560 NC_012441.1 1482623 1483534 D extensin family protein 1482623..1483534 Brucella melitensis ATCC 23457 7677194 YP_002733222.1 CDS BMEA_A1561 NC_012441.1 1483667 1484056 R thioesterase superfamily protein complement(1483667..1484056) Brucella melitensis ATCC 23457 7677195 YP_002733223.1 CDS uvrB NC_012441.1 1484984 1487806 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1484984..1487806 Brucella melitensis ATCC 23457 7677197 YP_002733224.1 CDS BMEA_A1565 NC_012441.1 1489236 1489451 D hypothetical protein 1489236..1489451 Brucella melitensis ATCC 23457 7677199 YP_002733225.1 CDS BMEA_A1566 NC_012441.1 1489467 1489790 D hypothetical protein 1489467..1489790 Brucella melitensis ATCC 23457 7677200 YP_002733226.1 CDS BMEA_A1567 NC_012441.1 1489868 1490374 D hypothetical protein 1489868..1490374 Brucella melitensis ATCC 23457 7677201 YP_002733227.1 CDS BMEA_A1568 NC_012441.1 1490433 1491089 R beta-lactamase domain-containing protein complement(1490433..1491089) Brucella melitensis ATCC 23457 7677202 YP_002733228.1 CDS BMEA_A1569 NC_012441.1 1491303 1491584 R hypothetical protein complement(1491303..1491584) Brucella melitensis ATCC 23457 7677203 YP_002733229.1 CDS BMEA_A1570 NC_012441.1 1491759 1492067 D hypothetical protein 1491759..1492067 Brucella melitensis ATCC 23457 7677204 YP_002733230.1 CDS BMEA_A1572 NC_012441.1 1492051 1492644 D HTH-type transcriptional regulator PetP 1492051..1492644 Brucella melitensis ATCC 23457 7677205 YP_002733231.1 CDS BMEA_A1573 NC_012441.1 1492726 1493451 D protein PetR 1492726..1493451 Brucella melitensis ATCC 23457 7677206 YP_002733232.1 CDS BMEA_A1574 NC_012441.1 1493595 1494938 D integral membrane sensor signal transduction histidine kinase 1493595..1494938 Brucella melitensis ATCC 23457 7677207 YP_002733233.1 CDS BMEA_A1575 NC_012441.1 1494942 1495070 D hypothetical protein 1494942..1495070 Brucella melitensis ATCC 23457 7677208 YP_002733234.1 CDS csaA NC_012441.1 1495370 1495717 R export-related chaperone CsaA complement(1495370..1495717) Brucella melitensis ATCC 23457 7677209 YP_002733235.1 CDS BMEA_A1578 NC_012441.1 1495857 1496357 R hypothetical protein complement(1495857..1496357) Brucella melitensis ATCC 23457 7677210 YP_002733236.1 CDS BMEA_A1579 NC_012441.1 1496419 1496511 R hypothetical protein complement(1496419..1496511) Brucella melitensis ATCC 23457 7677211 YP_002733237.1 CDS BMEA_A1580 NC_012441.1 1496786 1497106 R hypothetical protein complement(1496786..1497106) Brucella melitensis ATCC 23457 7677212 YP_002733238.1 CDS BMEA_A1581 NC_012441.1 1497124 1497264 R hypothetical protein complement(1497124..1497264) Brucella melitensis ATCC 23457 7677213 YP_002733239.1 CDS lgt NC_012441.1 1497291 1498136 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1497291..1498136 Brucella melitensis ATCC 23457 7677214 YP_002733240.1 CDS BMEA_A1583 NC_012441.1 1498129 1499226 D hypothetical protein 1498129..1499226 Brucella melitensis ATCC 23457 7677215 YP_002733241.1 CDS BMEA_A1584 NC_012441.1 1499406 1500257 D hypothetical protein 1499406..1500257 Brucella melitensis ATCC 23457 7677216 YP_002733242.1 CDS BMEA_A1585 NC_012441.1 1500370 1501521 D Xaa-Pro dipeptidase 1500370..1501521 Brucella melitensis ATCC 23457 7677217 YP_002733243.1 CDS BMEA_A1586 NC_012441.1 1501575 1502129 D hypothetical protein 1501575..1502129 Brucella melitensis ATCC 23457 7677218 YP_002733244.1 CDS prs NC_012441.1 1502468 1503400 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1502468..1503400 Brucella melitensis ATCC 23457 7677219 YP_002733245.1 CDS BMEA_A1588 NC_012441.1 1503548 1505089 R hypothetical protein complement(1503548..1505089) Brucella melitensis ATCC 23457 7677220 YP_002733246.1 CDS BMEA_A1589 NC_012441.1 1505523 1505693 D hypothetical protein 1505523..1505693 Brucella melitensis ATCC 23457 7677221 YP_002733247.1 CDS BMEA_A1590 NC_012441.1 1505781 1506404 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1505781..1506404 Brucella melitensis ATCC 23457 7677222 YP_002733248.1 CDS pth NC_012441.1 1506433 1507185 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1506433..1507185 Brucella melitensis ATCC 23457 7677223 YP_002733249.1 CDS ychF NC_012441.1 1507273 1508376 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1507273..1508376 Brucella melitensis ATCC 23457 7677224 YP_002733250.1 CDS BMEA_A1593 NC_012441.1 1508438 1508938 D MaoC domain-containing protein dehydratase 1508438..1508938 Brucella melitensis ATCC 23457 7677225 YP_002733251.1 CDS BMEA_A1594 NC_012441.1 1508935 1509417 D MaoC domain-containing protein dehydratase 1508935..1509417 Brucella melitensis ATCC 23457 7677226 YP_002733252.1 CDS apt NC_012441.1 1509459 1510019 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1509459..1510019) Brucella melitensis ATCC 23457 7677227 YP_002733253.1 CDS BMEA_A1596 NC_012441.1 1510064 1510180 D hypothetical protein 1510064..1510180 Brucella melitensis ATCC 23457 7677228 YP_002733254.1 CDS BMEA_A1597 NC_012441.1 1510327 1511214 R cytochrome c1 complement(1510327..1511214) Brucella melitensis ATCC 23457 7677229 YP_002733255.1 CDS BMEA_A1598 NC_012441.1 1511228 1512526 R cytochrome b complement(1511228..1512526) Brucella melitensis ATCC 23457 7677230 YP_002733256.1 CDS petA NC_012441.1 1512548 1513111 R ubiquinol-cytochrome c reductase iron-sulfur subunit complement(1512548..1513111) Brucella melitensis ATCC 23457 7677231 YP_002733257.1 CDS BMEA_A1600 NC_012441.1 1513363 1515231 R ABC transporter complement(1513363..1515231) Brucella melitensis ATCC 23457 7677232 YP_002733258.1 CDS BMEA_A1601 NC_012441.1 1515385 1517277 R ABC transporter complement(1515385..1517277) Brucella melitensis ATCC 23457 7677233 YP_002733259.1 CDS BMEA_A1602 NC_012441.1 1517398 1517877 D tRNA/rRNA methyltransferase SpoU 1517398..1517877 Brucella melitensis ATCC 23457 7677234 YP_002733260.1 CDS BMEA_A1603 NC_012441.1 1517912 1519024 D purine nucleoside permease 1517912..1519024 Brucella melitensis ATCC 23457 7677235 YP_002733261.1 CDS BMEA_A1604 NC_012441.1 1519136 1519396 R hypothetical protein complement(1519136..1519396) Brucella melitensis ATCC 23457 7677236 YP_002733262.1 CDS BMEA_A1605 NC_012441.1 1519690 1520601 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1519690..1520601 Brucella melitensis ATCC 23457 7677237 YP_002733263.1 CDS BMEA_A1606 NC_012441.1 1520635 1521129 R N-acetyltransferase GCN5 complement(1520635..1521129) Brucella melitensis ATCC 23457 7677238 YP_002733264.1 CDS BMEA_A1608 NC_012441.1 1522162 1523433 R CCA-adding protein complement(1522162..1523433) Brucella melitensis ATCC 23457 7677240 YP_002733265.1 CDS BMEA_A1609 NC_012441.1 1523430 1524053 R NUDIX hydrolase complement(1523430..1524053) Brucella melitensis ATCC 23457 7677241 YP_002733266.1 CDS BMEA_A1610 NC_012441.1 1524050 1524715 R hypothetical protein complement(1524050..1524715) Brucella melitensis ATCC 23457 7677242 YP_002733267.1 CDS BMEA_A1611 NC_012441.1 1524835 1525842 D hypothetical protein 1524835..1525842 Brucella melitensis ATCC 23457 7677243 YP_002733268.1 CDS BMEA_A1612 NC_012441.1 1525842 1526774 D hypothetical protein 1525842..1526774 Brucella melitensis ATCC 23457 7677244 YP_002733269.1 CDS BMEA_A1613 NC_012441.1 1526771 1529620 D hypothetical protein 1526771..1529620 Brucella melitensis ATCC 23457 7677245 YP_002733270.1 CDS BMEA_A1614 NC_012441.1 1529684 1531753 D hypothetical protein 1529684..1531753 Brucella melitensis ATCC 23457 7677246 YP_002733271.1 CDS BMEA_A1615 NC_012441.1 1531821 1532327 R N-acetyltransferase GCN5 complement(1531821..1532327) Brucella melitensis ATCC 23457 7677247 YP_002733272.1 CDS BMEA_A1616 NC_012441.1 1532631 1533614 D glutathione S-transferase 1532631..1533614 Brucella melitensis ATCC 23457 7677248 YP_002733273.1 CDS BMEA_A1617 NC_012441.1 1533762 1534445 D outer membrane protein alkL precursor 1533762..1534445 Brucella melitensis ATCC 23457 7677249 YP_002733274.1 CDS BMEA_A1618 NC_012441.1 1534479 1534934 R NUDIX hydrolase complement(1534479..1534934) Brucella melitensis ATCC 23457 7677250 YP_002733275.1 CDS BMEA_A1619 NC_012441.1 1535043 1535945 D metallophosphoesterase 1535043..1535945 Brucella melitensis ATCC 23457 7676366 YP_002733276.1 CDS leuA NC_012441.1 1536146 1537873 R 2-isopropylmalate synthase complement(1536146..1537873) Brucella melitensis ATCC 23457 7676367 YP_002733277.1 CDS BMEA_A1621 NC_012441.1 1538005 1538163 R hypothetical protein complement(1538005..1538163) Brucella melitensis ATCC 23457 7676368 YP_002733278.1 CDS BMEA_A1622 NC_012441.1 1538178 1539086 R cation diffusion facilitator family transporter complement(1538178..1539086) Brucella melitensis ATCC 23457 7676369 YP_002733279.1 CDS BMEA_A1623 NC_012441.1 1539096 1539377 D hypothetical protein 1539096..1539377 Brucella melitensis ATCC 23457 7676370 YP_002733280.1 CDS BMEA_A1624 NC_012441.1 1539555 1541750 R trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase complement(1539555..1541750) Brucella melitensis ATCC 23457 7676371 YP_002733281.1 CDS BMEA_A1626 NC_012441.1 1542429 1542890 D leucine-responsive regulatory protein 1542429..1542890 Brucella melitensis ATCC 23457 7676372 YP_002733282.1 CDS BMEA_A1627 NC_012441.1 1543031 1543441 D MarR family transcriptional regulator 1543031..1543441 Brucella melitensis ATCC 23457 7676373 YP_002733283.1 CDS BMEA_A1628 NC_012441.1 1543536 1544828 D major facilitator superfamily protein 1543536..1544828 Brucella melitensis ATCC 23457 7676374 YP_002733284.1 CDS BMEA_A1629 NC_012441.1 1544823 1545788 R hypothetical protein complement(1544823..1545788) Brucella melitensis ATCC 23457 7676375 YP_002733285.1 CDS BMEA_A1630 NC_012441.1 1545794 1546990 R hypothetical protein complement(1545794..1546990) Brucella melitensis ATCC 23457 7676376 YP_002733286.1 CDS BMEA_A1631 NC_012441.1 1546987 1547223 R hypothetical protein complement(1546987..1547223) Brucella melitensis ATCC 23457 7676377 YP_002733287.1 CDS choX NC_012441.1 1547426 1548394 D choline ABC transporter periplasmic binding protein 1547426..1548394 Brucella melitensis ATCC 23457 7676378 YP_002733288.1 CDS choW NC_012441.1 1548483 1549319 D choline ABC transporter permease 1548483..1549319 Brucella melitensis ATCC 23457 7676379 YP_002733289.1 CDS choV NC_012441.1 1549489 1550535 D choline ABC transporter ATP-binding protein 1549489..1550535 Brucella melitensis ATCC 23457 7676380 YP_002733290.1 CDS BMEA_A1635 NC_012441.1 1550809 1551657 R hypothetical protein complement(1550809..1551657) Brucella melitensis ATCC 23457 7676381 YP_002733291.1 CDS BMEA_A1636 NC_012441.1 1551654 1552502 R ABC transporter complement(1551654..1552502) Brucella melitensis ATCC 23457 7676382 YP_002733292.1 CDS BMEA_A1637 NC_012441.1 1552508 1553416 R dipeptide transport system permease DppC complement(1552508..1553416) Brucella melitensis ATCC 23457 7676383 YP_002733293.1 CDS BMEA_A1638 NC_012441.1 1553424 1554431 R dipeptide transport system permease DppB complement(1553424..1554431) Brucella melitensis ATCC 23457 7676384 YP_002733294.1 CDS BMEA_A1640 NC_012441.1 1556596 1556772 D pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 1556596..1556772 Brucella melitensis ATCC 23457 7676386 YP_002733295.1 CDS BMEA_A1641 NC_012441.1 1557013 1557240 R hypothetical protein complement(1557013..1557240) Brucella melitensis ATCC 23457 7676387 YP_002733296.1 CDS BMEA_A1642 NC_012441.1 1557230 1557577 D nodulation protein nolR 1557230..1557577 Brucella melitensis ATCC 23457 7676388 YP_002733297.1 CDS BMEA_A1643 NC_012441.1 1557607 1558437 D tRNA/rRNA methyltransferase SpoU 1557607..1558437 Brucella melitensis ATCC 23457 7676389 YP_002733298.1 CDS trmU NC_012441.1 1558659 1559855 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1558659..1559855) Brucella melitensis ATCC 23457 7676390 YP_002733299.1 CDS BMEA_A1645 NC_012441.1 1559893 1560051 R hypothetical protein complement(1559893..1560051) Brucella melitensis ATCC 23457 7676391 YP_002733300.1 CDS BMEA_A1646 NC_012441.1 1560160 1560435 D hypothetical protein 1560160..1560435 Brucella melitensis ATCC 23457 7676392 YP_002733301.1 CDS BMEA_A1647 NC_012441.1 1560978 1561913 R myosin-14 complement(1560978..1561913) Brucella melitensis ATCC 23457 7676393 YP_002733302.1 CDS BMEA_A1648 NC_012441.1 1562143 1562739 R hypothetical protein complement(1562143..1562739) Brucella melitensis ATCC 23457 7676394 YP_002733303.1 CDS BMEA_A1649 NC_012441.1 1563009 1563152 R hypothetical protein complement(1563009..1563152) Brucella melitensis ATCC 23457 7676395 YP_002733304.1 CDS BMEA_A1650 NC_012441.1 1563151 1563780 D hypothetical protein 1563151..1563780 Brucella melitensis ATCC 23457 7676396 YP_002733305.1 CDS BMEA_A1651 NC_012441.1 1563893 1564591 R hypothetical protein complement(1563893..1564591) Brucella melitensis ATCC 23457 7676397 YP_002733306.1 CDS BMEA_A1652 NC_012441.1 1565123 1565515 D hypothetical protein 1565123..1565515 Brucella melitensis ATCC 23457 7676398 YP_002733307.1 CDS BMEA_A1653 NC_012441.1 1565599 1566723 R pleiotropic regulatory protein complement(1565599..1566723) Brucella melitensis ATCC 23457 7676399 YP_002733308.1 CDS BMEA_A1654 NC_012441.1 1566883 1567839 R oxidoreductase domain-containing protein complement(1566883..1567839) Brucella melitensis ATCC 23457 7676400 YP_002733309.1 CDS BMEA_A1656 NC_012441.1 1568241 1568495 D hypothetical protein 1568241..1568495 Brucella melitensis ATCC 23457 7676402 YP_002733310.1 CDS BMEA_A1657 NC_012441.1 1568671 1569453 R lacto-N-neotetraose biosynthesis glycosyl transferase complement(1568671..1569453) Brucella melitensis ATCC 23457 7676403 YP_002733311.1 CDS BMEA_A1659 NC_012441.1 1570198 1573305 D PAS domain S-box-containing protein 1570198..1573305 Brucella melitensis ATCC 23457 7676405 YP_002733312.1 CDS BMEA_A1660 NC_012441.1 1573525 1573656 R hypothetical protein complement(1573525..1573656) Brucella melitensis ATCC 23457 7676406 YP_002733313.1 CDS BMEA_A1661 NC_012441.1 1574046 1575983 D AsmA family protein 1574046..1575983 Brucella melitensis ATCC 23457 7676407 YP_002733314.1 CDS BMEA_A1662 NC_012441.1 1575991 1576812 R Spermidine/putrescine transport system permease potC complement(1575991..1576812) Brucella melitensis ATCC 23457 7676408 YP_002733315.1 CDS BMEA_A1663 NC_012441.1 1576814 1577725 R binding-protein-dependent transport systems inner membrane protein complement(1576814..1577725) Brucella melitensis ATCC 23457 7676409 YP_002733316.1 CDS BMEA_A1664 NC_012441.1 1577741 1578886 R polyamine ABC transporter ATP-binding protein complement(1577741..1578886) Brucella melitensis ATCC 23457 7676410 YP_002733317.1 CDS BMEA_A1665 NC_012441.1 1579128 1580231 R hypothetical protein complement(1579128..1580231) Brucella melitensis ATCC 23457 7676411 YP_002733318.1 CDS aceA NC_012441.1 1582114 1583403 D isocitrate lyase 1582114..1583403 Brucella melitensis ATCC 23457 7676413 YP_002733319.1 CDS BMEA_A1668 NC_012441.1 1583438 1583674 D hypothetical protein 1583438..1583674 Brucella melitensis ATCC 23457 7676414 YP_002733320.1 CDS BMEA_A1670 NC_012441.1 1584387 1585154 D Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1584387..1585154 Brucella melitensis ATCC 23457 7676416 YP_002733321.1 CDS BMEA_A1671 NC_012441.1 1585220 1586014 D hypothetical protein 1585220..1586014 Brucella melitensis ATCC 23457 7676417 YP_002733322.1 CDS BMEA_A1672 NC_012441.1 1586021 1587781 D hypothetical protein 1586021..1587781 Brucella melitensis ATCC 23457 7676418 YP_002733323.1 CDS BMEA_A1673 NC_012441.1 1587797 1588411 D hypothetical protein 1587797..1588411 Brucella melitensis ATCC 23457 7676419 YP_002733324.1 CDS BMEA_A1674 NC_012441.1 1588635 1589243 D outer membrane protein Omp31 1588635..1589243 Brucella melitensis ATCC 23457 7676420 YP_002733325.1 CDS BMEA_A1675 NC_012441.1 1589380 1590930 R patatin complement(1589380..1590930) Brucella melitensis ATCC 23457 7676421 YP_002733326.1 CDS BMEA_A1676 NC_012441.1 1591483 1591764 D hypothetical protein 1591483..1591764 Brucella melitensis ATCC 23457 7676422 YP_002733327.1 CDS BMEA_A1677 NC_012441.1 1592041 1592784 R dihydroxyacetone kinase subunit L complement(1592041..1592784) Brucella melitensis ATCC 23457 7676423 YP_002733328.1 CDS BMEA_A1678 NC_012441.1 1592754 1594838 R glycerone kinase complement(1592754..1594838) Brucella melitensis ATCC 23457 7676424 YP_002733329.1 CDS BMEA_A1679 NC_012441.1 1594997 1595653 R dihydroxyacetone kinase subunit L complement(1594997..1595653) Brucella melitensis ATCC 23457 7676425 YP_002733330.1 CDS BMEA_A1680 NC_012441.1 1595650 1596678 R glycerone kinase complement(1595650..1596678) Brucella melitensis ATCC 23457 7676426 YP_002733331.1 CDS BMEA_A1682 NC_012441.1 1597541 1598530 R rhizopine-binding protein complement(1597541..1598530) Brucella melitensis ATCC 23457 7676428 YP_002733332.1 CDS BMEA_A1683 NC_012441.1 1598706 1599710 R hypothetical protein complement(1598706..1599710) Brucella melitensis ATCC 23457 7676429 YP_002733333.1 CDS BMEA_A1684 NC_012441.1 1599806 1601227 R ribose/galactose/methyl galactoside import ATP-binding protein 2 complement(1599806..1601227) Brucella melitensis ATCC 23457 7676430 YP_002733334.1 CDS BMEA_A1685 NC_012441.1 1601579 1601896 D hypothetical protein 1601579..1601896 Brucella melitensis ATCC 23457 7676431 YP_002733335.1 CDS BMEA_A1686 NC_012441.1 1602026 1602154 R hypothetical protein complement(1602026..1602154) Brucella melitensis ATCC 23457 7676432 YP_002733336.1 CDS BMEA_A1687 NC_012441.1 1602253 1603914 D choline dehydrogenase 1602253..1603914 Brucella melitensis ATCC 23457 7676596 YP_002733337.1 CDS BMEA_A1690 NC_012441.1 1604563 1604715 D hypothetical protein 1604563..1604715 Brucella melitensis ATCC 23457 7676599 YP_002733338.1 CDS BMEA_A1692 NC_012441.1 1607670 1607912 D hypothetical protein 1607670..1607912 Brucella melitensis ATCC 23457 7676601 YP_002733339.1 CDS BMEA_A1696 NC_012441.1 1610613 1611434 R regulatory protein IclR complement(1610613..1611434) Brucella melitensis ATCC 23457 7676605 YP_002733340.1 CDS BMEA_A1697 NC_012441.1 1611552 1613003 D succinate-semialdehyde dehydrogenase 1611552..1613003 Brucella melitensis ATCC 23457 7676606 YP_002733341.1 CDS BMEA_A1698 NC_012441.1 1613120 1613710 D hypothetical protein 1613120..1613710 Brucella melitensis ATCC 23457 7676607 YP_002733342.1 CDS BMEA_A1699 NC_012441.1 1613823 1614341 D disulfide bond formation protein B 1613823..1614341 Brucella melitensis ATCC 23457 7676608 YP_002733343.1 CDS BMEA_A1700 NC_012441.1 1614358 1614930 R HNH endonuclease complement(1614358..1614930) Brucella melitensis ATCC 23457 7676609 YP_002733344.1 CDS BMEA_A1701 NC_012441.1 1615204 1615902 R HhH-GPD family protein complement(1615204..1615902) Brucella melitensis ATCC 23457 7676610 YP_002733345.1 CDS BMEA_A1702 NC_012441.1 1615924 1616799 D this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1615924..1616799 Brucella melitensis ATCC 23457 7676611 YP_002733346.1 CDS glcB NC_012441.1 1616942 1619128 D catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 1616942..1619128 Brucella melitensis ATCC 23457 7676612 YP_002733347.1 CDS BMEA_A1704 NC_012441.1 1619203 1619304 D hypothetical protein 1619203..1619304 Brucella melitensis ATCC 23457 7676613 YP_002733348.1 CDS BMEA_A1705 NC_012441.1 1619433 1619927 D N-acetyltransferase GCN5 1619433..1619927 Brucella melitensis ATCC 23457 7676614 YP_002733349.1 CDS rpoH NC_012441.1 1619986 1620897 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(1619986..1620897) Brucella melitensis ATCC 23457 7676615 YP_002733350.1 CDS BMEA_A1707 NC_012441.1 1621328 1622371 R pseudouridine synthase complement(1621328..1622371) Brucella melitensis ATCC 23457 7676616 YP_002733351.1 CDS BMEA_A1708 NC_012441.1 1622388 1622864 D hypothetical protein 1622388..1622864 Brucella melitensis ATCC 23457 7676617 YP_002733352.1 CDS BMEA_A1709 NC_012441.1 1622898 1623071 D hypothetical protein 1622898..1623071 Brucella melitensis ATCC 23457 7676618 YP_002733353.1 CDS BMEA_A1711 NC_012441.1 1623243 1623668 D ferric uptake regulation protein 1623243..1623668 Brucella melitensis ATCC 23457 7676620 YP_002733354.1 CDS BMEA_A1712 NC_012441.1 1623904 1624839 R signal transduction histidine kinase complement(1623904..1624839) Brucella melitensis ATCC 23457 7676621 YP_002733355.1 CDS BMEA_A1713 NC_012441.1 1625107 1625316 R hypothetical protein complement(1625107..1625316) Brucella melitensis ATCC 23457 7676622 YP_002733356.1 CDS BMEA_A1714 NC_012441.1 1625421 1626215 R in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator complement(1625421..1626215) Brucella melitensis ATCC 23457 7676623 YP_002733357.1 CDS BMEA_A1715 NC_012441.1 1626661 1627233 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1626661..1627233 Brucella melitensis ATCC 23457 7676624 YP_002733358.1 CDS BMEA_A1716 NC_012441.1 1627433 1628875 D signal transduction histidine kinase 1627433..1628875 Brucella melitensis ATCC 23457 7676625 YP_002733359.1 CDS BMEA_A1717 NC_012441.1 1628936 1629367 R hypothetical protein complement(1628936..1629367) Brucella melitensis ATCC 23457 7676626 YP_002733360.1 CDS BMEA_A1718 NC_012441.1 1629376 1629729 R hypothetical protein complement(1629376..1629729) Brucella melitensis ATCC 23457 7676627 YP_002733361.1 CDS BMEA_A1720 NC_012441.1 1630908 1631066 R hypothetical protein complement(1630908..1631066) Brucella melitensis ATCC 23457 7676629 YP_002733362.1 CDS BMEA_A1721 NC_012441.1 1631197 1631400 D hypothetical protein 1631197..1631400 Brucella melitensis ATCC 23457 7676630 YP_002733363.1 CDS exbB NC_012441.1 1631517 1632440 D TonB-system energizer ExbB 1631517..1632440 Brucella melitensis ATCC 23457 7676631 YP_002733364.1 CDS exbD NC_012441.1 1632446 1632970 D TonB system transport protein ExbD 1632446..1632970 Brucella melitensis ATCC 23457 7676632 YP_002733365.1 CDS BMEA_A1724 NC_012441.1 1632937 1633788 D TonB family C-terminal domain-containing protein 1632937..1633788 Brucella melitensis ATCC 23457 7676633 YP_002733366.1 CDS BMEA_A1725 NC_012441.1 1633831 1634601 R hypothetical protein complement(1633831..1634601) Brucella melitensis ATCC 23457 7676634 YP_002733367.1 CDS BMEA_A1727 NC_012441.1 1636574 1637800 R RND family efflux transporter complement(1636574..1637800) Brucella melitensis ATCC 23457 7676636 YP_002733368.1 CDS dut NC_012441.1 1638035 1638508 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1638035..1638508) Brucella melitensis ATCC 23457 7676637 YP_002733369.1 CDS BMEA_A1729 NC_012441.1 1638730 1639200 R AsnC family transcriptional regulator complement(1638730..1639200) Brucella melitensis ATCC 23457 7676638 YP_002733370.1 CDS BMEA_A1730 NC_012441.1 1639346 1639561 D hypothetical protein 1639346..1639561 Brucella melitensis ATCC 23457 7676639 YP_002733371.1 CDS BMEA_A1734 NC_012441.1 1641670 1643022 D hypothetical protein 1641670..1643022 Brucella melitensis ATCC 23457 7676643 YP_002733372.1 CDS BMEA_A1735 NC_012441.1 1643131 1644528 R hypothetical protein complement(1643131..1644528) Brucella melitensis ATCC 23457 7676644 YP_002733373.1 CDS purA NC_012441.1 1644841 1646130 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1644841..1646130) Brucella melitensis ATCC 23457 7676645 YP_002733374.1 CDS BMEA_A1737 NC_012441.1 1646448 1646957 R N-acetyltransferase GCN5 complement(1646448..1646957) Brucella melitensis ATCC 23457 7676646 YP_002733375.1 CDS serA NC_012441.1 1646962 1648563 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(1646962..1648563) Brucella melitensis ATCC 23457 7676647 YP_002733376.1 CDS BMEA_A1739 NC_012441.1 1648706 1649881 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase complement(1648706..1649881) Brucella melitensis ATCC 23457 7676648 YP_002733377.1 CDS BMEA_A1741 NC_012441.1 1650032 1650988 R bile acid:sodium symporter complement(1650032..1650988) Brucella melitensis ATCC 23457 7676649 YP_002733378.1 CDS BMEA_A1742 NC_012441.1 1651169 1651993 R opacity type porin complement(1651169..1651993) Brucella melitensis ATCC 23457 7676650 YP_002733379.1 CDS glmM NC_012441.1 1652178 1653557 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1652178..1653557) Brucella melitensis ATCC 23457 7676651 YP_002733380.1 CDS ftsH NC_012441.1 1653838 1655772 R ATP-dependent metalloprotease FtsH complement(1653838..1655772) Brucella melitensis ATCC 23457 7676652 YP_002733381.1 CDS tilS NC_012441.1 1655908 1657254 R tRNA(Ile)-lysidine synthetase complement(1655908..1657254) Brucella melitensis ATCC 23457 7676653 YP_002733382.1 CDS ygbF NC_012441.1 1657270 1658736 R Tol-Pal system protein YbgF complement(1657270..1658736) Brucella melitensis ATCC 23457 7676654 YP_002733383.1 CDS pal NC_012441.1 1659133 1659639 R peptidoglycan-associated lipoprotein complement(1659133..1659639) Brucella melitensis ATCC 23457 7676655 YP_002733384.1 CDS BMEA_A1748 NC_012441.1 1659688 1659867 R hypothetical protein complement(1659688..1659867) Brucella melitensis ATCC 23457 7676656 YP_002733385.1 CDS tolB NC_012441.1 1659927 1661258 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1659927..1661258) Brucella melitensis ATCC 23457 7676657 YP_002733386.1 CDS BMEA_A1750 NC_012441.1 1661314 1662384 R hypothetical protein complement(1661314..1662384) Brucella melitensis ATCC 23457 7676658 YP_002733387.1 CDS tolR NC_012441.1 1662392 1662844 R protein TolR complement(1662392..1662844) Brucella melitensis ATCC 23457 7676659 YP_002733388.1 CDS tolQ NC_012441.1 1662891 1663601 R protein TolQ complement(1662891..1663601) Brucella melitensis ATCC 23457 7676660 YP_002733389.1 CDS BMEA_A1753 NC_012441.1 1663637 1663804 D hypothetical protein 1663637..1663804 Brucella melitensis ATCC 23457 7676661 YP_002733390.1 CDS BMEA_A1754 NC_012441.1 1663976 1664257 R thioesterase superfamily protein complement(1663976..1664257) Brucella melitensis ATCC 23457 7676662 YP_002733391.1 CDS ruvB NC_012441.1 1664422 1665462 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1664422..1665462) Brucella melitensis ATCC 23457 7677476 YP_002733392.1 CDS ruvA NC_012441.1 1665503 1666120 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1665503..1666120) Brucella melitensis ATCC 23457 7676936 YP_002733393.1 CDS ruvC NC_012441.1 1666125 1666646 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1666125..1666646) Brucella melitensis ATCC 23457 7676937 YP_002733394.1 CDS BMEA_A1758 NC_012441.1 1666748 1667254 R hypothetical protein complement(1666748..1667254) Brucella melitensis ATCC 23457 7676938 YP_002733395.1 CDS BMEA_A1759 NC_012441.1 1667742 1668923 R hypothetical protein complement(1667742..1668923) Brucella melitensis ATCC 23457 7676939 YP_002733396.1 CDS BMEA_A1760 NC_012441.1 1669168 1669833 D catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1669168..1669833 Brucella melitensis ATCC 23457 7676940 YP_002733397.1 CDS BMEA_A1761 NC_012441.1 1669834 1670922 D Sel1 domain-containing protein repeat-containing protein 1669834..1670922 Brucella melitensis ATCC 23457 7676941 YP_002733398.1 CDS efp NC_012441.1 1671187 1671747 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1671187..1671747 Brucella melitensis ATCC 23457 7676942 YP_002733399.1 CDS BMEA_A1763 NC_012441.1 1671933 1672724 D inositol-phosphate phosphatase 1671933..1672724 Brucella melitensis ATCC 23457 7676943 YP_002733400.1 CDS BMEA_A1764 NC_012441.1 1672729 1672839 D hypothetical protein 1672729..1672839 Brucella melitensis ATCC 23457 7676944 YP_002733401.1 CDS BMEA_A1765 NC_012441.1 1672979 1674028 D hypothetical protein 1672979..1674028 Brucella melitensis ATCC 23457 7676945 YP_002733402.1 CDS BMEA_A1766 NC_012441.1 1674035 1675066 D hypothetical protein 1674035..1675066 Brucella melitensis ATCC 23457 7676946 YP_002733403.1 CDS BMEA_A1767 NC_012441.1 1675100 1676899 R ABC transporter ATP-binding protein/permease complement(1675100..1676899) Brucella melitensis ATCC 23457 7676947 YP_002733404.1 CDS rpmE NC_012441.1 1677215 1677436 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1677215..1677436 Brucella melitensis ATCC 23457 7676948 YP_002733405.1 CDS BMEA_A1769 NC_012441.1 1677664 1678410 R hypothetical protein complement(1677664..1678410) Brucella melitensis ATCC 23457 7676949 YP_002733406.1 CDS BMEA_A1770 NC_012441.1 1678631 1679323 D GntR family transcriptional regulator 1678631..1679323 Brucella melitensis ATCC 23457 7676950 YP_002733407.1 CDS BMEA_A1771 NC_012441.1 1679485 1680060 D BioY protein 1679485..1680060 Brucella melitensis ATCC 23457 7676951 YP_002733408.1 CDS BMEA_A1772 NC_012441.1 1680071 1680499 D hypothetical protein 1680071..1680499 Brucella melitensis ATCC 23457 7676952 YP_002733409.1 CDS BMEA_A1773 NC_012441.1 1680512 1681255 R integral membrane protein TerC complement(1680512..1681255) Brucella melitensis ATCC 23457 7676953 YP_002733410.1 CDS BMEA_A1774 NC_012441.1 1681466 1682290 R hypothetical protein complement(1681466..1682290) Brucella melitensis ATCC 23457 7676954 YP_002733411.1 CDS BMEA_A1775 NC_012441.1 1682399 1682995 R 5,10-methenyltetrahydrofolate synthetase complement(1682399..1682995) Brucella melitensis ATCC 23457 7676955 YP_002733412.1 CDS BMEA_A1778 NC_012441.1 1683383 1683748 R hypothetical protein complement(1683383..1683748) Brucella melitensis ATCC 23457 7676957 YP_002733413.1 CDS BMEA_A1779 NC_012441.1 1683758 1684030 R hypothetical protein complement(1683758..1684030) Brucella melitensis ATCC 23457 7676958 YP_002733414.1 CDS tkt NC_012441.1 1684447 1686438 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1684447..1686438 Brucella melitensis ATCC 23457 7676959 YP_002733415.1 CDS gap NC_012441.1 1686579 1687586 D glyceraldehyde-3-phosphate dehydrogenase 1686579..1687586 Brucella melitensis ATCC 23457 7676960 YP_002733416.1 CDS BMEA_A1782 NC_012441.1 1687654 1688844 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1687654..1688844 Brucella melitensis ATCC 23457 7676961 YP_002733417.1 CDS BMEA_A1783 NC_012441.1 1689135 1689299 R hypothetical protein complement(1689135..1689299) Brucella melitensis ATCC 23457 7676962 YP_002733418.1 CDS BMEA_A1784 NC_012441.1 1689573 1691483 D propionate--CoA ligase 1689573..1691483 Brucella melitensis ATCC 23457 7676963 YP_002733419.1 CDS BMEA_A1786 NC_012441.1 1691867 1692052 D hypothetical protein 1691867..1692052 Brucella melitensis ATCC 23457 7676964 YP_002733420.1 CDS BMEA_A1787 NC_012441.1 1692059 1692760 D hypothetical protein 1692059..1692760 Brucella melitensis ATCC 23457 7676965 YP_002733421.1 CDS BMEA_A1788 NC_012441.1 1693163 1693570 D hypothetical protein 1693163..1693570 Brucella melitensis ATCC 23457 7676966 YP_002733422.1 CDS BMEA_A1789 NC_012441.1 1693648 1694337 R hypothetical protein complement(1693648..1694337) Brucella melitensis ATCC 23457 7676967 YP_002733423.1 CDS BMEA_A1790 NC_012441.1 1694465 1695469 R quinone oxidoreductase, PIG3 family protein complement(1694465..1695469) Brucella melitensis ATCC 23457 7676968 YP_002733424.1 CDS BMEA_A1791 NC_012441.1 1695662 1695853 D hypothetical protein 1695662..1695853 Brucella melitensis ATCC 23457 7676969 YP_002733425.1 CDS BMEA_A1792 NC_012441.1 1695951 1697189 D major facilitator superfamily protein 1695951..1697189 Brucella melitensis ATCC 23457 7676970 YP_002733426.1 CDS BMEA_A1793 NC_012441.1 1697332 1697511 R hypothetical protein complement(1697332..1697511) Brucella melitensis ATCC 23457 7676971 YP_002733427.1 CDS BMEA_A1794 NC_012441.1 1697570 1697791 R hypothetical protein complement(1697570..1697791) Brucella melitensis ATCC 23457 7676972 YP_002733428.1 CDS BMEA_A1795 NC_012441.1 1697905 1698108 D hypothetical protein 1697905..1698108 Brucella melitensis ATCC 23457 7676973 YP_002733429.1 CDS purE NC_012441.1 1698206 1698694 D phosphoribosylaminoimidazole carboxylase catalytic subunit 1698206..1698694 Brucella melitensis ATCC 23457 7676974 YP_002733430.1 CDS purK NC_012441.1 1698711 1699799 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1698711..1699799 Brucella melitensis ATCC 23457 7676975 YP_002733431.1 CDS BMEA_A1798 NC_012441.1 1699966 1700160 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1699966..1700160 Brucella melitensis ATCC 23457 7676976 YP_002733432.1 CDS BMEA_A1799 NC_012441.1 1700198 1700887 D hypothetical protein 1700198..1700887 Brucella melitensis ATCC 23457 7676977 YP_002733433.1 CDS pyk NC_012441.1 1701139 1702575 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1701139..1702575) Brucella melitensis ATCC 23457 7676978 YP_002733434.1 CDS BMEA_A1801 NC_012441.1 1702572 1703033 R hypothetical protein complement(1702572..1703033) Brucella melitensis ATCC 23457 7676979 YP_002733435.1 CDS BMEA_A1802 NC_012441.1 1703274 1704092 D N-formylglutamate amidohydrolase 1703274..1704092 Brucella melitensis ATCC 23457 7676980 YP_002733436.1 CDS BMEA_A1803 NC_012441.1 1704089 1704250 D hypothetical protein 1704089..1704250 Brucella melitensis ATCC 23457 7676981 YP_002733437.1 CDS BMEA_A1804 NC_012441.1 1704265 1704525 D hypothetical protein 1704265..1704525 Brucella melitensis ATCC 23457 7676982 YP_002733438.1 CDS BMEA_A1805 NC_012441.1 1704617 1706434 R ABC transporter complement(1704617..1706434) Brucella melitensis ATCC 23457 7676983 YP_002733439.1 CDS BMEA_A1807 NC_012441.1 1706582 1706866 R hypothetical protein complement(1706582..1706866) Brucella melitensis ATCC 23457 7676984 YP_002733440.1 CDS BMEA_A1808 NC_012441.1 1707000 1707656 R thiamine pyrophosphokinase complement(1707000..1707656) Brucella melitensis ATCC 23457 7676985 YP_002733441.1 CDS thiB NC_012441.1 1707963 1708967 D part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 1707963..1708967 Brucella melitensis ATCC 23457 7676986 YP_002733442.1 CDS thiP NC_012441.1 1708943 1710595 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1708943..1710595 Brucella melitensis ATCC 23457 7676987 YP_002733443.1 CDS BMEA_A1812 NC_012441.1 1710592 1711317 D thiamine ABC transporter ATP-binding protein 1710592..1711317 Brucella melitensis ATCC 23457 7676988 YP_002733444.1 CDS BMEA_A1813 NC_012441.1 1711584 1713065 D peptidase M48 Ste24p 1711584..1713065 Brucella melitensis ATCC 23457 7676989 YP_002733445.1 CDS BMEA_A1814 NC_012441.1 1713092 1713820 D MOSC domain-containing protein 1713092..1713820 Brucella melitensis ATCC 23457 7676990 YP_002733446.1 CDS BMEA_A1815 NC_012441.1 1713908 1714843 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 complement(1713908..1714843) Brucella melitensis ATCC 23457 7676991 YP_002733447.1 CDS BMEA_A1816 NC_012441.1 1714884 1715087 D hypothetical protein 1714884..1715087 Brucella melitensis ATCC 23457 7676992 YP_002733448.1 CDS BMEA_A1817 NC_012441.1 1715007 1715216 R hypothetical protein complement(1715007..1715216) Brucella melitensis ATCC 23457 7676993 YP_002733449.1 CDS BMEA_A1818 NC_012441.1 1715188 1715763 R hypothetical protein complement(1715188..1715763) Brucella melitensis ATCC 23457 7676994 YP_002733450.1 CDS BMEA_A1819 NC_012441.1 1716281 1716619 R ferredoxin-2 complement(1716281..1716619) Brucella melitensis ATCC 23457 7676995 YP_002733451.1 CDS BMEA_A1820 NC_012441.1 1716983 1717384 R RNA-binding S4 domain-containing protein complement(1716983..1717384) Brucella melitensis ATCC 23457 7676996 YP_002733452.1 CDS BMEA_A1821 NC_012441.1 1717420 1720506 R ATP-dependent helicase complement(1717420..1720506) Brucella melitensis ATCC 23457 7676997 YP_002733453.1 CDS BMEA_A1822 NC_012441.1 1720599 1722113 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(1720599..1722113) Brucella melitensis ATCC 23457 7676998 YP_002733454.1 CDS BMEA_A1824 NC_012441.1 1722259 1722690 D hypothetical protein 1722259..1722690 Brucella melitensis ATCC 23457 7676999 YP_002733455.1 CDS rpmF NC_012441.1 1722822 1723001 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1722822..1723001) Brucella melitensis ATCC 23457 7677000 YP_002733456.1 CDS mtgA NC_012441.1 1723161 1723958 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(1723161..1723958) Brucella melitensis ATCC 23457 7677001 YP_002733457.1 CDS BMEA_A1827 NC_012441.1 1724082 1724996 D polyprenyl synthetase 1724082..1724996 Brucella melitensis ATCC 23457 7677002 YP_002733458.1 CDS ispG NC_012441.1 1725004 1726266 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(1725004..1726266) Brucella melitensis ATCC 23457 7677003 YP_002733459.1 CDS BMEA_A1829 NC_012441.1 1726434 1727225 D 3-hydroxybutyrate dehydrogenase 1726434..1727225 Brucella melitensis ATCC 23457 7677004 YP_002733460.1 CDS BMEA_A1830 NC_012441.1 1727243 1728436 R membrane protein MosC complement(1727243..1728436) Brucella melitensis ATCC 23457 7677005 YP_002733461.1 CDS pyc NC_012441.1 1728498 1731974 R biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase complement(1728498..1731974) Brucella melitensis ATCC 23457 7677006 YP_002733462.1 CDS BMEA_A1832 NC_012441.1 1732240 1733355 R Leu/Ile/Val-binding protein complement(1732240..1733355) Brucella melitensis ATCC 23457 7677007 YP_002733463.1 CDS BMEA_A1833 NC_012441.1 1733498 1733629 R hypothetical protein complement(1733498..1733629) Brucella melitensis ATCC 23457 7677008 YP_002733464.1 CDS BMEA_A1835 NC_012441.1 1733648 1733785 D hypothetical protein 1733648..1733785 Brucella melitensis ATCC 23457 7677009 YP_002733465.1 CDS BMEA_A1836 NC_012441.1 1733976 1735091 R Leu/Ile/Val-binding protein precursor complement(1733976..1735091) Brucella melitensis ATCC 23457 7677010 YP_002733466.1 CDS BMEA_A1837 NC_012441.1 1735243 1735587 R hypothetical protein complement(1735243..1735587) Brucella melitensis ATCC 23457 7677011 YP_002733467.1 CDS BMEA_A1838 NC_012441.1 1735597 1736346 R hypothetical protein complement(1735597..1736346) Brucella melitensis ATCC 23457 7677012 YP_002733468.1 CDS BMEA_A1839 NC_012441.1 1736343 1737683 R ABC transporter complement(1736343..1737683) Brucella melitensis ATCC 23457 7677013 YP_002733469.1 CDS BMEA_A1840 NC_012441.1 1737683 1739062 R inner-membrane translocator complement(1737683..1739062) Brucella melitensis ATCC 23457 7677014 YP_002733470.1 CDS BMEA_A1841 NC_012441.1 1739065 1739988 R hypothetical protein complement(1739065..1739988) Brucella melitensis ATCC 23457 7677015 YP_002733471.1 CDS BMEA_A1842 NC_012441.1 1740267 1741268 R hydroxyproline-2-epimerase complement(1740267..1741268) Brucella melitensis ATCC 23457 7677016 YP_002733472.1 CDS BMEA_A1844 NC_012441.1 1742574 1742759 D hypothetical protein 1742574..1742759 Brucella melitensis ATCC 23457 7677331 YP_002733473.1 CDS BMEA_A1845 NC_012441.1 1742815 1743510 D GntR family transcriptional regulator 1742815..1743510 Brucella melitensis ATCC 23457 7677332 YP_002733474.1 CDS BMEA_A1846 NC_012441.1 1743583 1744020 R transcriptional regulator slyA complement(1743583..1744020) Brucella melitensis ATCC 23457 7677333 YP_002733475.1 CDS atpC NC_012441.1 1744363 1744770 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1744363..1744770) Brucella melitensis ATCC 23457 7677334 YP_002733476.1 CDS atpD NC_012441.1 1744895 1746460 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1744895..1746460) Brucella melitensis ATCC 23457 7677335 YP_002733477.1 CDS atpG NC_012441.1 1746588 1747466 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1746588..1747466) Brucella melitensis ATCC 23457 7677336 YP_002733478.1 CDS atpA NC_012441.1 1747488 1749017 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1747488..1749017) Brucella melitensis ATCC 23457 7677337 YP_002733479.1 CDS atpH NC_012441.1 1749017 1749577 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1749017..1749577) Brucella melitensis ATCC 23457 7677338 YP_002733480.1 CDS BMEA_A1853 NC_012441.1 1749859 1750272 R hypothetical protein complement(1749859..1750272) Brucella melitensis ATCC 23457 7677339 YP_002733481.1 CDS priA NC_012441.1 1750339 1752573 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1750339..1752573) Brucella melitensis ATCC 23457 7677340 YP_002733482.1 CDS talC NC_012441.1 1752683 1753336 D similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; putative translaldolase 1752683..1753336 Brucella melitensis ATCC 23457 7677341 YP_002733483.1 CDS BMEA_A1856 NC_012441.1 1753479 1754060 R hypothetical protein complement(1753479..1754060) Brucella melitensis ATCC 23457 7677342 YP_002733484.1 CDS leuS NC_012441.1 1754047 1756680 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1754047..1756680) Brucella melitensis ATCC 23457 7677343 YP_002733485.1 CDS BMEA_A1858 NC_012441.1 1756803 1757483 D hypothetical protein 1756803..1757483 Brucella melitensis ATCC 23457 7677344 YP_002733486.1 CDS BMEA_A1859 NC_012441.1 1757496 1758026 R hypothetical protein complement(1757496..1758026) Brucella melitensis ATCC 23457 7677345 YP_002733487.1 CDS BMEA_A1860 NC_012441.1 1758097 1758384 R Usg family protein complement(1758097..1758384) Brucella melitensis ATCC 23457 7677346 YP_002733488.1 CDS acsA NC_012441.1 1758725 1760680 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1758725..1760680 Brucella melitensis ATCC 23457 7677347 YP_002733489.1 CDS BMEA_A1862 NC_012441.1 1760836 1761054 R hypothetical protein complement(1760836..1761054) Brucella melitensis ATCC 23457 7677348 YP_002733490.1 CDS BMEA_A1863 NC_012441.1 1761186 1762163 D putative metalloprotease; heat shock protein HtpX 1761186..1762163 Brucella melitensis ATCC 23457 7677349 YP_002733491.1 CDS BMEA_A1864 NC_012441.1 1762179 1763576 D Fmu domain-containing protein, Sun 1762179..1763576 Brucella melitensis ATCC 23457 7677350 YP_002733492.1 CDS BMEA_A1865 NC_012441.1 1763697 1765439 D hypothetical protein 1763697..1765439 Brucella melitensis ATCC 23457 7677351 YP_002733493.1 CDS purH NC_012441.1 1765546 1767162 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1765546..1767162 Brucella melitensis ATCC 23457 7677352 YP_002733494.1 CDS BMEA_A1868 NC_012441.1 1768668 1768820 D hypothetical protein 1768668..1768820 Brucella melitensis ATCC 23457 7677354 YP_002733495.1 CDS BMEA_A1869 NC_012441.1 1768798 1773600 R NAD-glutamate dehydrogenase complement(1768798..1773600) Brucella melitensis ATCC 23457 7677355 YP_002733496.1 CDS BMEA_A1870 NC_012441.1 1773865 1774506 R hypothetical protein complement(1773865..1774506) Brucella melitensis ATCC 23457 7677356 YP_002733497.1 CDS BMEA_A1871 NC_012441.1 1774519 1775286 R hypothetical protein complement(1774519..1775286) Brucella melitensis ATCC 23457 7677357 YP_002733498.1 CDS BMEA_A1872 NC_012441.1 1775367 1775990 R LemA family protein complement(1775367..1775990) Brucella melitensis ATCC 23457 7677358 YP_002733499.1 CDS BMEA_A1873 NC_012441.1 1775987 1776160 R hypothetical protein complement(1775987..1776160) Brucella melitensis ATCC 23457 7677359 YP_002733500.1 CDS rpsP NC_012441.1 1776260 1776631 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1776260..1776631) Brucella melitensis ATCC 23457 7677360 YP_002733501.1 CDS BMEA_A1875 NC_012441.1 1776698 1777012 R catalyzes the interconversion of chorismate to prephenate; chorismate mutase complement(1776698..1777012) Brucella melitensis ATCC 23457 7677361 YP_002733502.1 CDS ffh NC_012441.1 1777018 1778589 R signal recognition particle protein complement(1777018..1778589) Brucella melitensis ATCC 23457 7677362 YP_002733503.1 CDS BMEA_A1877 NC_012441.1 1779024 1779851 D lytic murein transglycosylase 1779024..1779851 Brucella melitensis ATCC 23457 7677363 YP_002733504.1 CDS BMEA_A1878 NC_012441.1 1779915 1780556 R carbonic anhydrase complement(1779915..1780556) Brucella melitensis ATCC 23457 7677364 YP_002733505.1 CDS BMEA_A1879 NC_012441.1 1780730 1781626 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1780730..1781626) Brucella melitensis ATCC 23457 7677365 YP_002733506.1 CDS BMEA_A1880 NC_012441.1 1781628 1781915 R hypothetical protein complement(1781628..1781915) Brucella melitensis ATCC 23457 7677366 YP_002733507.1 CDS mmsA NC_012441.1 1782189 1783685 R methylmalonate-semialdehyde dehydrogenase complement(1782189..1783685) Brucella melitensis ATCC 23457 7677367 YP_002733508.1 CDS BMEA_A1882 NC_012441.1 1783792 1784718 D LysR family transcriptional regulator 1783792..1784718 Brucella melitensis ATCC 23457 7677368 YP_002733509.1 CDS BMEA_A1883 NC_012441.1 1784929 1785573 R hypothetical protein complement(1784929..1785573) Brucella melitensis ATCC 23457 7677369 YP_002733510.1 CDS BMEA_A1885 NC_012441.1 1785641 1785895 R hypothetical protein complement(1785641..1785895) Brucella melitensis ATCC 23457 7677370 YP_002733511.1 CDS BMEA_A1886 NC_012441.1 1786011 1786547 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1786011..1786547) Brucella melitensis ATCC 23457 7677371 YP_002733512.1 CDS BMEA_A1887 NC_012441.1 1786765 1788093 R carboxyl-terminal protease complement(1786765..1788093) Brucella melitensis ATCC 23457 7677372 YP_002733513.1 CDS BMEA_A1888 NC_012441.1 1788083 1789432 R leucine zipper protein 1 complement(1788083..1789432) Brucella melitensis ATCC 23457 7677373 YP_002733514.1 CDS BMEA_A1889 NC_012441.1 1789545 1790444 R hypothetical protein complement(1789545..1790444) Brucella melitensis ATCC 23457 7677374 YP_002733515.1 CDS BMEA_A1890 NC_012441.1 1790562 1791086 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(1790562..1791086) Brucella melitensis ATCC 23457 7677375 YP_002733516.1 CDS BMEA_A1891 NC_012441.1 1791105 1791476 R iojap-like protein complement(1791105..1791476) Brucella melitensis ATCC 23457 7677376 YP_002733517.1 CDS nadD NC_012441.1 1791639 1792313 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1791639..1792313) Brucella melitensis ATCC 23457 7677377 YP_002733518.1 CDS proA NC_012441.1 1792313 1793596 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1792313..1793596) Brucella melitensis ATCC 23457 7677378 YP_002733519.1 CDS proB NC_012441.1 1793606 1794742 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1793606..1794742) Brucella melitensis ATCC 23457 7677379 YP_002733520.1 CDS BMEA_A1895 NC_012441.1 1794770 1795795 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1794770..1795795) Brucella melitensis ATCC 23457 7677380 YP_002733521.1 CDS BMEA_A1896 NC_012441.1 1797104 1797661 R N-acetyltransferase GCN5 complement(1797104..1797661) Brucella melitensis ATCC 23457 7677381 YP_002733522.1 CDS BMEA_A1897 NC_012441.1 1797924 1798406 R N-acetyltransferase GCN5 complement(1797924..1798406) Brucella melitensis ATCC 23457 7677382 YP_002733523.1 CDS rpmA NC_012441.1 1798485 1798754 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1798485..1798754) Brucella melitensis ATCC 23457 7677383 YP_002733524.1 CDS rplU NC_012441.1 1798780 1799208 R 50S ribosomal protein L21 complement(1798780..1799208) Brucella melitensis ATCC 23457 7677384 YP_002733525.1 CDS BMEA_A1901 NC_012441.1 1799726 1800604 D transposase and inactivated derivatives-like protein 1799726..1800604 Brucella melitensis ATCC 23457 7677386 YP_002733526.1 CDS BMEA_A1902 NC_012441.1 1800821 1802773 D hypothetical protein 1800821..1802773 Brucella melitensis ATCC 23457 7677387 YP_002733527.1 CDS BMEA_A1903 NC_012441.1 1802770 1803444 D hypothetical protein 1802770..1803444 Brucella melitensis ATCC 23457 7677388 YP_002733528.1 CDS BMEA_A1904 NC_012441.1 1803857 1803970 D hypothetical protein 1803857..1803970 Brucella melitensis ATCC 23457 7677389 YP_002733529.1 CDS BMEA_A1905 NC_012441.1 1804003 1804689 R transposase and inactivated derivatives-like protein complement(1804003..1804689) Brucella melitensis ATCC 23457 7677390 YP_002733530.1 CDS BMEA_A1906 NC_012441.1 1804800 1806239 R hypothetical protein complement(1804800..1806239) Brucella melitensis ATCC 23457 7677391 YP_002733531.1 CDS BMEA_A1907 NC_012441.1 1806415 1807089 R hypothetical protein complement(1806415..1807089) Brucella melitensis ATCC 23457 7677392 YP_002733532.1 CDS BMEA_A1908 NC_012441.1 1807407 1807574 D hypothetical protein 1807407..1807574 Brucella melitensis ATCC 23457 7677393 YP_002733533.1 CDS BMEA_A1911 NC_012441.1 1807962 1808114 D hypothetical protein 1807962..1808114 Brucella melitensis ATCC 23457 7677560 YP_002733534.1 CDS BMEA_A1916 NC_012441.1 1814227 1816182 D peptidase M23B 1814227..1816182 Brucella melitensis ATCC 23457 7677565 YP_002733535.1 CDS BMEA_A1917 NC_012441.1 1816250 1817476 R ErfK/YbiS/YcfS/YnhG family protein complement(1816250..1817476) Brucella melitensis ATCC 23457 7677566 YP_002733536.1 CDS clpB NC_012441.1 1818149 1820773 R ATP-dependent chaperone ClpB complement(1818149..1820773) Brucella melitensis ATCC 23457 7677567 YP_002733537.1 CDS BMEA_A1919 NC_012441.1 1820972 1821730 R hypothetical protein complement(1820972..1821730) Brucella melitensis ATCC 23457 7677568 YP_002733538.1 CDS BMEA_A1920 NC_012441.1 1821711 1821983 R hypothetical protein complement(1821711..1821983) Brucella melitensis ATCC 23457 7677569 YP_002733539.1 CDS BMEA_A1921 NC_012441.1 1822045 1822191 D hypothetical protein 1822045..1822191 Brucella melitensis ATCC 23457 7677570 YP_002733540.1 CDS hemK NC_012441.1 1822175 1823062 R methyltransferase, HemK family protein complement(1822175..1823062) Brucella melitensis ATCC 23457 7677571 YP_002733541.1 CDS prfA NC_012441.1 1823059 1824138 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1823059..1824138) Brucella melitensis ATCC 23457 7677572 YP_002733542.1 CDS ptsI NC_012441.1 1824335 1826605 R phosphoenolpyruvate-protein phosphotransferase complement(1824335..1826605) Brucella melitensis ATCC 23457 7677573 YP_002733543.1 CDS BMEA_A1925 NC_012441.1 1826933 1828204 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1826933..1828204) Brucella melitensis ATCC 23457 7677574 YP_002733544.1 CDS ubiG NC_012441.1 1828422 1829168 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1828422..1829168 Brucella melitensis ATCC 23457 7677575 YP_002733545.1 CDS BMEA_A1927 NC_012441.1 1829174 1830067 R hypothetical protein complement(1829174..1830067) Brucella melitensis ATCC 23457 7677576 YP_002733546.1 CDS BMEA_A1928 NC_012441.1 1830095 1830520 R hypothetical protein complement(1830095..1830520) Brucella melitensis ATCC 23457 7677577 YP_002733547.1 CDS BMEA_A1929 NC_012441.1 1830526 1831380 R nitrilase/cyanide hydratase and apolipoprotein n-acyltransferase complement(1830526..1831380) Brucella melitensis ATCC 23457 7677578 YP_002733548.1 CDS grxC NC_012441.1 1831391 1831657 R glutaredoxin 3 complement(1831391..1831657) Brucella melitensis ATCC 23457 7677579 YP_002733549.1 CDS BMEA_A1931 NC_012441.1 1831641 1831763 D hypothetical protein 1831641..1831763 Brucella melitensis ATCC 23457 7677580 YP_002733550.1 CDS BMEA_A1932 NC_012441.1 1831741 1832529 R competence protein F complement(1831741..1832529) Brucella melitensis ATCC 23457 7677581 YP_002733551.1 CDS BMEA_A1933 NC_012441.1 1832712 1833605 D methyltransferase type 11 1832712..1833605 Brucella melitensis ATCC 23457 7677582 YP_002733552.1 CDS BMEA_A1935 NC_012441.1 1833744 1834982 D major facilitator superfamily protein 1833744..1834982 Brucella melitensis ATCC 23457 7677583 YP_002733553.1 CDS BMEA_A1936 NC_012441.1 1835008 1835487 R hypothetical protein complement(1835008..1835487) Brucella melitensis ATCC 23457 7677584 YP_002733554.1 CDS BMEA_A1937 NC_012441.1 1835903 1837474 R HemY domain-containing protein complement(1835903..1837474) Brucella melitensis ATCC 23457 7677585 YP_002733555.1 CDS BMEA_A1938 NC_012441.1 1837487 1838863 R hypothetical protein complement(1837487..1838863) Brucella melitensis ATCC 23457 7677586 YP_002733556.1 CDS BMEA_A1939 NC_012441.1 1838946 1839653 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; uroporphyrinogen-III synthase complement(1838946..1839653) Brucella melitensis ATCC 23457 7677587 YP_002733557.1 CDS hemC NC_012441.1 1839677 1840621 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(1839677..1840621) Brucella melitensis ATCC 23457 7677588 YP_002733558.1 CDS BMEA_A1941 NC_012441.1 1840740 1841819 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1840740..1841819 Brucella melitensis ATCC 23457 7677589 YP_002733559.1 CDS BMEA_A1942 NC_012441.1 1841816 1842796 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1841816..1842796 Brucella melitensis ATCC 23457 7677590 YP_002733560.1 CDS BMEA_A1943 NC_012441.1 1842798 1843088 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1842798..1843088 Brucella melitensis ATCC 23457 7677591 YP_002733561.1 CDS BMEA_A1944 NC_012441.1 1843101 1843529 D hypothetical protein 1843101..1843529 Brucella melitensis ATCC 23457 7677592 YP_002733562.1 CDS BMEA_A1945 NC_012441.1 1843481 1844185 D hypothetical protein 1843481..1844185 Brucella melitensis ATCC 23457 7677593 YP_002733563.1 CDS BMEA_A1946 NC_012441.1 1844231 1845088 R hypothetical protein complement(1844231..1845088) Brucella melitensis ATCC 23457 7677594 YP_002733564.1 CDS BMEA_A1947 NC_012441.1 1845204 1846697 D GntR family transcriptional regulator 1845204..1846697 Brucella melitensis ATCC 23457 7677595 YP_002733565.1 CDS BMEA_A1948 NC_012441.1 1846759 1849212 R DNA translocase ftsK complement(1846759..1849212) Brucella melitensis ATCC 23457 7677596 YP_002733566.1 CDS amt NC_012441.1 1849422 1850723 R ammonium transporter complement(1849422..1850723) Brucella melitensis ATCC 23457 7677597 YP_002733567.1 CDS BMEA_A1950 NC_012441.1 1850697 1850855 D hypothetical protein 1850697..1850855 Brucella melitensis ATCC 23457 7677598 YP_002733568.1 CDS tesB NC_012441.1 1850946 1851899 R acyl-CoA thioesterase II complement(1850946..1851899) Brucella melitensis ATCC 23457 7677599 YP_002733569.1 CDS BMEA_A1952 NC_012441.1 1852068 1853312 D 2-octaprenyl-6-methoxyphenyl hydroxylase 1852068..1853312 Brucella melitensis ATCC 23457 7677600 YP_002733570.1 CDS BMEA_A1953 NC_012441.1 1853398 1853769 R glyoxalase/bleomycin resistance protein/dioxygenase complement(1853398..1853769) Brucella melitensis ATCC 23457 7677601 YP_002733571.1 CDS BMEA_A1955 NC_012441.1 1854138 1854917 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(1854138..1854917) Brucella melitensis ATCC 23457 7677602 YP_002733572.1 CDS sdhA NC_012441.1 1854933 1856774 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(1854933..1856774) Brucella melitensis ATCC 23457 7677603 YP_002733573.1 CDS sdhD NC_012441.1 1856782 1857177 R succinate dehydrogenase hydrophobic membrane anchor protein complement(1856782..1857177) Brucella melitensis ATCC 23457 7677604 YP_002733574.1 CDS sdhC NC_012441.1 1857191 1857589 R succinate dehydrogenase cytochrome b556 subunit complement(1857191..1857589) Brucella melitensis ATCC 23457 7677605 YP_002733575.1 CDS BMEA_A1959 NC_012441.1 1857631 1857825 D hypothetical protein 1857631..1857825 Brucella melitensis ATCC 23457 7677606 YP_002733576.1 CDS BMEA_A1960 NC_012441.1 1857934 1858392 R hypothetical protein complement(1857934..1858392) Brucella melitensis ATCC 23457 7677607 YP_002733577.1 CDS leuC NC_012441.1 1858649 1860058 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(1858649..1860058) Brucella melitensis ATCC 23457 7677608 YP_002733578.1 CDS rplS NC_012441.1 1860269 1860706 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1860269..1860706) Brucella melitensis ATCC 23457 7677609 YP_002733579.1 CDS BMEA_A1965 NC_012441.1 1862612 1862863 R hypothetical protein complement(1862612..1862863) Brucella melitensis ATCC 23457 7677611 YP_002733580.1 CDS BMEA_A1966 NC_012441.1 1862860 1863270 R hypothetical protein complement(1862860..1863270) Brucella melitensis ATCC 23457 7677612 YP_002733581.1 CDS BMEA_A1967 NC_012441.1 1863263 1863625 R hypothetical protein complement(1863263..1863625) Brucella melitensis ATCC 23457 7677613 YP_002733582.1 CDS BMEA_A1968 NC_012441.1 1863622 1863945 R NIPSNAP family protein complement(1863622..1863945) Brucella melitensis ATCC 23457 7677614 YP_002733583.1 CDS BMEA_A1969 NC_012441.1 1864016 1864681 D ArsR family transcriptional regulator 1864016..1864681 Brucella melitensis ATCC 23457 7677615 YP_002733584.1 CDS trmD NC_012441.1 1864816 1865550 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1864816..1865550) Brucella melitensis ATCC 23457 7677616 YP_002733585.1 CDS rimM NC_012441.1 1865547 1866116 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1865547..1866116) Brucella melitensis ATCC 23457 7677617 YP_002733586.1 CDS BMEA_A1972 NC_012441.1 1866153 1866278 R hypothetical protein complement(1866153..1866278) Brucella melitensis ATCC 23457 7677618 YP_002733587.1 CDS xerC NC_012441.1 1866340 1867287 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1866340..1867287 Brucella melitensis ATCC 23457 7677619 YP_002733588.1 CDS BMEA_A1974 NC_012441.1 1867341 1868342 D GumN family protein 1867341..1868342 Brucella melitensis ATCC 23457 7677620 YP_002733589.1 CDS lpdA NC_012441.1 1868546 1869949 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1868546..1869949) Brucella melitensis ATCC 23457 7677621 YP_002733590.1 CDS BMEA_A1976 NC_012441.1 1870118 1870660 R hypothetical protein complement(1870118..1870660) Brucella melitensis ATCC 23457 7677622 YP_002733591.1 CDS BMEA_A1977 NC_012441.1 1870731 1871369 R lysine exporter protein lYSE/YGGA complement(1870731..1871369) Brucella melitensis ATCC 23457 7677623 YP_002733592.1 CDS BMEA_A1978 NC_012441.1 1871411 1871824 R hypothetical protein complement(1871411..1871824) Brucella melitensis ATCC 23457 7677624 YP_002733593.1 CDS sucB NC_012441.1 1871834 1873060 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(1871834..1873060) Brucella melitensis ATCC 23457 7677625 YP_002733594.1 CDS sucA NC_012441.1 1873122 1876136 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(1873122..1876136) Brucella melitensis ATCC 23457 7677626 YP_002733595.1 CDS BMEA_A1981 NC_012441.1 1876273 1876422 D hypothetical protein 1876273..1876422 Brucella melitensis ATCC 23457 7677627 YP_002733596.1 CDS BMEA_A1982 NC_012441.1 1876412 1877314 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(1876412..1877314) Brucella melitensis ATCC 23457 7677628 YP_002733597.1 CDS BMEA_A1983 NC_012441.1 1877318 1878514 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(1877318..1878514) Brucella melitensis ATCC 23457 7677629 YP_002733598.1 CDS mdh NC_012441.1 1878621 1879583 R Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase complement(1878621..1879583) Brucella melitensis ATCC 23457 7677630 YP_002733599.1 CDS BMEA_A1985 NC_012441.1 1879703 1879945 R hypothetical protein complement(1879703..1879945) Brucella melitensis ATCC 23457 7677631 YP_002733600.1 CDS BMEA_A1986 NC_012441.1 1880022 1881185 R AFG1 family ATPase complement(1880022..1881185) Brucella melitensis ATCC 23457 7677632 YP_002733601.1 CDS BMEA_A1987 NC_012441.1 1881305 1881838 R hypothetical protein complement(1881305..1881838) Brucella melitensis ATCC 23457 7677633 YP_002733602.1 CDS BMEA_A1988 NC_012441.1 1881967 1882170 R hypothetical protein complement(1881967..1882170) Brucella melitensis ATCC 23457 7677634 YP_002733603.1 CDS dapF NC_012441.1 1882201 1883112 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1882201..1883112 Brucella melitensis ATCC 23457 7677635 YP_002733604.1 CDS BMEA_A1990 NC_012441.1 1883112 1884395 D MiaB-like tRNA modifying enzyme 1883112..1884395 Brucella melitensis ATCC 23457 7677636 YP_002733605.1 CDS ftsY NC_012441.1 1884417 1885814 D signal recognition particle-docking protein FtsY 1884417..1885814 Brucella melitensis ATCC 23457 7677637 YP_002733606.1 CDS ispZ NC_012441.1 1885814 1886476 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1885814..1886476 Brucella melitensis ATCC 23457 7677638 YP_002733607.1 CDS gloB NC_012441.1 1886500 1887282 D hydroxyacylglutathione hydrolase 1886500..1887282 Brucella melitensis ATCC 23457 7677721 YP_002733608.1 CDS BMEA_A1994 NC_012441.1 1887329 1887820 D hypothetical protein 1887329..1887820 Brucella melitensis ATCC 23457 7677722 YP_002733609.1 CDS BMEA_A1995 NC_012441.1 1887885 1888190 R hypothetical protein complement(1887885..1888190) Brucella melitensis ATCC 23457 7677723 YP_002733610.1 CDS BMEA_A1996 NC_012441.1 1888302 1888718 R mutator MutT protein complement(1888302..1888718) Brucella melitensis ATCC 23457 7677724 YP_002733611.1 CDS BMEA_A1997 NC_012441.1 1888715 1889506 R N-acetyltransferase GCN5 complement(1888715..1889506) Brucella melitensis ATCC 23457 7677725 YP_002733612.1 CDS argJ NC_012441.1 1889564 1890805 R bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase complement(1889564..1890805) Brucella melitensis ATCC 23457 7677726 YP_002733613.1 CDS BMEA_A1999 NC_012441.1 1891039 1891182 R hypothetical protein complement(1891039..1891182) Brucella melitensis ATCC 23457 7677727 YP_002733614.1 CDS BMEA_A2000 NC_012441.1 1891243 1892238 R PpiC-type peptidyl-prolyl cis-trans isomerase complement(1891243..1892238) Brucella melitensis ATCC 23457 7677728 YP_002733615.1 CDS BMEA_A2001 NC_012441.1 1892366 1892533 R hypothetical protein complement(1892366..1892533) Brucella melitensis ATCC 23457 7677729 YP_002733616.1 CDS secA NC_012441.1 1892577 1895297 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1892577..1895297 Brucella melitensis ATCC 23457 7677730 YP_002733617.1 CDS BMEA_A2003 NC_012441.1 1895325 1895465 D hypothetical protein 1895325..1895465 Brucella melitensis ATCC 23457 7677731 YP_002733618.1 CDS BMEA_A2004 NC_012441.1 1896074 1897360 D hypothetical protein 1896074..1897360 Brucella melitensis ATCC 23457 7677732 YP_002733619.1 CDS BMEA_A2005 NC_012441.1 1897529 1899163 D sulfatase 1897529..1899163 Brucella melitensis ATCC 23457 7677733 YP_002733620.1 CDS BMEA_A2006 NC_012441.1 1899517 1899618 D hypothetical protein 1899517..1899618 Brucella melitensis ATCC 23457 7677734 YP_002733621.1 CDS BMEA_A2008 NC_012441.1 1900359 1901315 R regulatory protein complement(1900359..1901315) Brucella melitensis ATCC 23457 7677736 YP_002733622.1 CDS BMEA_A2009 NC_012441.1 1901355 1901540 R hypothetical protein complement(1901355..1901540) Brucella melitensis ATCC 23457 7677737 YP_002733623.1 CDS BMEA_A2011 NC_012441.1 1902538 1903236 D His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 1902538..1903236 Brucella melitensis ATCC 23457 7677739 YP_002733624.1 CDS BMEA_A2012 NC_012441.1 1903241 1903963 D His/Glu/Gln/Arg/opine family amino acid ABC transporter permease 1903241..1903963 Brucella melitensis ATCC 23457 7677740 YP_002733625.1 CDS BMEA_A2013 NC_012441.1 1903960 1904775 D octopine permease ATP-binding protein P 1903960..1904775 Brucella melitensis ATCC 23457 7677741 YP_002733626.1 CDS BMEA_A2014 NC_012441.1 1904796 1905809 D proclavaminate amidinohydrolase 1904796..1905809 Brucella melitensis ATCC 23457 7677742 YP_002733627.1 CDS BMEA_A2015 NC_012441.1 1905818 1907269 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1905818..1907269 Brucella melitensis ATCC 23457 7677743 YP_002733628.1 CDS BMEA_A2016 NC_012441.1 1907253 1908008 D glutamate/glutamine/aspartate/asparagine transport ATP-binding protein bztD 1907253..1908008 Brucella melitensis ATCC 23457 7677744 YP_002733629.1 CDS BMEA_A2017 NC_012441.1 1908017 1909015 D L-asparaginase 1908017..1909015 Brucella melitensis ATCC 23457 7677745 YP_002733630.1 CDS BMEA_A2018 NC_012441.1 1909152 1909835 R GntR family transcriptional regulator complement(1909152..1909835) Brucella melitensis ATCC 23457 7677746 YP_002733631.1 CDS BMEA_A2019 NC_012441.1 1909905 1910849 R L-asparaginase complement(1909905..1910849) Brucella melitensis ATCC 23457 7677747 YP_002733632.1 CDS BMEA_A2020 NC_012441.1 1910927 1912234 D major facilitator superfamily protein 1910927..1912234 Brucella melitensis ATCC 23457 7677748 YP_002733633.1 CDS BMEA_A2021 NC_012441.1 1912721 1912873 R hypothetical protein complement(1912721..1912873) Brucella melitensis ATCC 23457 7677749 YP_002733634.1 CDS BMEA_A2022 NC_012441.1 1912920 1914203 R catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase complement(1912920..1914203) Brucella melitensis ATCC 23457 7677750 YP_002733635.1 CDS BMEA_A2023 NC_012441.1 1914383 1914832 R UspA domain-containing protein complement(1914383..1914832) Brucella melitensis ATCC 23457 7677751 YP_002733636.1 CDS cysK NC_012441.1 1915052 1916062 D cysteine synthase A 1915052..1916062 Brucella melitensis ATCC 23457 7677752 YP_002733637.1 CDS BMEA_A2025 NC_012441.1 1916144 1916392 R hypothetical protein complement(1916144..1916392) Brucella melitensis ATCC 23457 7677753 YP_002733638.1 CDS BMEA_A2026 NC_012441.1 1916552 1917427 R converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase complement(1916552..1917427) Brucella melitensis ATCC 23457 7677754 YP_002733639.1 CDS BMEA_A2027 NC_012441.1 1917911 1918840 R hypothetical protein complement(1917911..1918840) Brucella melitensis ATCC 23457 7677755 YP_002733640.1 CDS BMEA_A2028 NC_012441.1 1918993 1919739 R electron transfer flavoprotein subunit beta complement(1918993..1919739) Brucella melitensis ATCC 23457 7677756 YP_002733641.1 CDS BMEA_A2029 NC_012441.1 1920075 1920773 D ExsB protein 1920075..1920773 Brucella melitensis ATCC 23457 7677757 YP_002733642.1 CDS queD NC_012441.1 1920773 1921138 D queuosine biosynthesis protein QueD 1920773..1921138 Brucella melitensis ATCC 23457 7677758 YP_002733643.1 CDS queE NC_012441.1 1921138 1921893 D radical SAM domain-containing protein 1921138..1921893 Brucella melitensis ATCC 23457 7677759 YP_002733644.1 CDS BMEA_A2032 NC_012441.1 1922030 1922617 R ATP:cobalamin adenosyltransferase complement(1922030..1922617) Brucella melitensis ATCC 23457 7677760 YP_002733645.1 CDS BMEA_A2033 NC_012441.1 1922619 1922822 R hypothetical protein complement(1922619..1922822) Brucella melitensis ATCC 23457 7677761 YP_002733646.1 CDS BMEA_A2034 NC_012441.1 1922852 1923694 R short chain dehydrogenase complement(1922852..1923694) Brucella melitensis ATCC 23457 7677762 YP_002733647.1 CDS yihY NC_012441.1 1923852 1924712 D YihY family protein 1923852..1924712 Brucella melitensis ATCC 23457 7677763 YP_002733648.1 CDS BMEA_A2036 NC_012441.1 1924730 1925215 D hypothetical protein 1924730..1925215 Brucella melitensis ATCC 23457 7677764 YP_002733649.1 CDS BMEA_A2037 NC_012441.1 1925223 1925939 R redoxin domain-containing protein complement(1925223..1925939) Brucella melitensis ATCC 23457 7677765 YP_002733650.1 CDS argH NC_012441.1 1925993 1927393 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1925993..1927393 Brucella melitensis ATCC 23457 7677766 YP_002733651.1 CDS BMEA_A2039 NC_012441.1 1927498 1927686 D hypothetical protein 1927498..1927686 Brucella melitensis ATCC 23457 7677767 YP_002733652.1 CDS lysA NC_012441.1 1927714 1928979 D diaminopimelate decarboxylase 1927714..1928979 Brucella melitensis ATCC 23457 7677768 YP_002733653.1 CDS BMEA_A2041 NC_012441.1 1929078 1931723 D hypothetical protein 1929078..1931723 Brucella melitensis ATCC 23457 7677769 YP_002733654.1 CDS hpt NC_012441.1 1931763 1932299 R hypoxanthine phosphoribosyltransferase complement(1931763..1932299) Brucella melitensis ATCC 23457 7677770 YP_002733655.1 CDS BMEA_A2043 NC_012441.1 1932448 1933227 D methyltransferase domain-containing protein 1932448..1933227 Brucella melitensis ATCC 23457 7677771 YP_002733656.1 CDS hisC NC_012441.1 1933372 1934478 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1933372..1934478 Brucella melitensis ATCC 23457 7677772 YP_002733657.1 CDS BMEA_A2045 NC_012441.1 1934483 1935448 D dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1934483..1935448 Brucella melitensis ATCC 23457 7677773 YP_002733658.1 CDS BMEA_A2047 NC_012441.1 1936456 1936659 R hypothetical protein complement(1936456..1936659) Brucella melitensis ATCC 23457 7677774 YP_002733659.1 CDS BMEA_A2048 NC_012441.1 1936648 1937208 D ChaC family protein 1936648..1937208 Brucella melitensis ATCC 23457 7677775 YP_002733660.1 CDS BMEA_A2050 NC_012441.1 1937370 1937486 R hypothetical protein complement(1937370..1937486) Brucella melitensis ATCC 23457 7677777 YP_002733661.1 CDS BMEA_A2051 NC_012441.1 1937541 1937831 D hypothetical protein 1937541..1937831 Brucella melitensis ATCC 23457 7677778 YP_002733662.1 CDS BMEA_A2052 NC_012441.1 1938002 1938532 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(1938002..1938532) Brucella melitensis ATCC 23457 7677779 YP_002733663.1 CDS BMEA_A2053 NC_012441.1 1938685 1939467 R phospholipid/glycerol acyltransferase complement(1938685..1939467) Brucella melitensis ATCC 23457 7677780 YP_002733664.1 CDS BMEA_A2054 NC_012441.1 1939646 1940179 R hypothetical protein complement(1939646..1940179) Brucella melitensis ATCC 23457 7677781 YP_002733665.1 CDS BMEA_A2055 NC_012441.1 1940545 1941546 R hypothetical protein complement(1940545..1941546) Brucella melitensis ATCC 23457 7677782 YP_002733666.1 CDS ftsE NC_012441.1 1941539 1942198 R cell division ATP-binding protein FtsE complement(1941539..1942198) Brucella melitensis ATCC 23457 7677783 YP_002733667.1 CDS BMEA_A2057 NC_012441.1 1942203 1942379 R hypothetical protein complement(1942203..1942379) Brucella melitensis ATCC 23457 7677784 YP_002733668.1 CDS BMEA_A2058 NC_012441.1 1942507 1942779 R hypothetical protein complement(1942507..1942779) Brucella melitensis ATCC 23457 7677785 YP_002733669.1 CDS BMEA_A2059 NC_012441.1 1942556 1942873 D hypothetical protein 1942556..1942873 Brucella melitensis ATCC 23457 7677786 YP_002733670.1 CDS BMEA_A2060 NC_012441.1 1943257 1943943 D porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1943257..1943943 Brucella melitensis ATCC 23457 7677787 YP_002733671.1 CDS BMEA_A2061 NC_012441.1 1944324 1945019 D outer membrane lipoprotein carrier protein LolA 1944324..1945019 Brucella melitensis ATCC 23457 7677788 YP_002733672.1 CDS BMEA_A2062 NC_012441.1 1945122 1945928 D exodeoxyribonuclease III 1945122..1945928 Brucella melitensis ATCC 23457 7677789 YP_002733673.1 CDS BMEA_A2063 NC_012441.1 1945934 1946395 R lysophospholipase nte-1 complement(1945934..1946395) Brucella melitensis ATCC 23457 7677790 YP_002733674.1 CDS BMEA_A2064 NC_012441.1 1946430 1947113 R transcriptional regulator BasR/PmrA complement(1946430..1947113) Brucella melitensis ATCC 23457 7677791 YP_002733675.1 CDS BMEA_A2066 NC_012441.1 1947321 1947866 D hypothetical protein 1947321..1947866 Brucella melitensis ATCC 23457 7677792 YP_002733676.1 CDS BMEA_A2067 NC_012441.1 1947927 1948226 D hypothetical protein 1947927..1948226 Brucella melitensis ATCC 23457 7677793 YP_002733677.1 CDS BMEA_A2069 NC_012441.1 1948255 1949403 R sulfated surface glycoprotein 185 precursor complement(1948255..1949403) Brucella melitensis ATCC 23457 7677794 YP_002733678.1 CDS BMEA_A2070 NC_012441.1 1949774 1950853 R hypothetical protein complement(1949774..1950853) Brucella melitensis ATCC 23457 7677795 YP_002733679.1 CDS BMEA_A2071 NC_012441.1 1951180 1951569 D hypothetical protein 1951180..1951569 Brucella melitensis ATCC 23457 7677796 YP_002733680.1 CDS BMEA_A2072 NC_012441.1 1951656 1953212 R glycoprotein X complement(1951656..1953212) Brucella melitensis ATCC 23457 7677797 YP_002733681.1 CDS BMEA_A2074 NC_012441.1 1958313 1958984 R hypothetical protein complement(1958313..1958984) Brucella melitensis ATCC 23457 7677799 YP_002733682.1 CDS rpmB NC_012441.1 1959064 1959357 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1959064..1959357) Brucella melitensis ATCC 23457 7677800 YP_002733683.1 CDS BMEA_A2076 NC_012441.1 1959719 1960534 D hypothetical protein 1959719..1960534 Brucella melitensis ATCC 23457 7677801 YP_002733684.1 CDS BMEA_A2077 NC_012441.1 1960646 1961068 R MerR family transcriptional regulator complement(1960646..1961068) Brucella melitensis ATCC 23457 7676365 YP_002733685.1 CDS BMEA_A2078 NC_012441.1 1961157 1963571 D heavy metal translocating P-type ATPase 1961157..1963571 Brucella melitensis ATCC 23457 7678045 YP_002733686.1 CDS BMEA_A2079 NC_012441.1 1963978 1964727 D hypothetical protein 1963978..1964727 Brucella melitensis ATCC 23457 7678046 YP_002733687.1 CDS BMEA_A2080 NC_012441.1 1964754 1965839 D hypothetical protein 1964754..1965839 Brucella melitensis ATCC 23457 7678047 YP_002733688.1 CDS BMEA_A2081 NC_012441.1 1966012 1967913 R cobaltochelatase subunit CobT complement(1966012..1967913) Brucella melitensis ATCC 23457 7678048 YP_002733689.1 CDS BMEA_A2082 NC_012441.1 1968021 1969007 R cobaltochelatase subunit CobS complement(1968021..1969007) Brucella melitensis ATCC 23457 7678049 YP_002733690.1 CDS BMEA_A2083 NC_012441.1 1969086 1969316 D hypothetical protein 1969086..1969316 Brucella melitensis ATCC 23457 7678050 YP_002733691.1 CDS BMEA_A2084 NC_012441.1 1969294 1969923 R DnaJ domain-containing protein complement(1969294..1969923) Brucella melitensis ATCC 23457 7678051 YP_002733692.1 CDS BMEA_A2085 NC_012441.1 1969920 1970117 R hypothetical protein complement(1969920..1970117) Brucella melitensis ATCC 23457 7678052 YP_002733693.1 CDS BMEA_A2086 NC_012441.1 1970110 1970424 D BolA protein 1970110..1970424 Brucella melitensis ATCC 23457 7678053 YP_002733694.1 CDS BMEA_A2087 NC_012441.1 1970449 1971756 R hypothetical protein complement(1970449..1971756) Brucella melitensis ATCC 23457 7678054 YP_002733695.1 CDS aroB NC_012441.1 1971820 1972956 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1971820..1972956) Brucella melitensis ATCC 23457 7678055 YP_002733696.1 CDS BMEA_A2089 NC_012441.1 1973049 1973651 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(1973049..1973651) Brucella melitensis ATCC 23457 7678056 YP_002733697.1 CDS BMEA_A2090 NC_012441.1 1973797 1973982 D hypothetical protein 1973797..1973982 Brucella melitensis ATCC 23457 7678057 YP_002733698.1 CDS xerD NC_012441.1 1973985 1974908 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1973985..1974908 Brucella melitensis ATCC 23457 7678058 YP_002733699.1 CDS accA NC_012441.1 1975047 1976000 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1975047..1976000 Brucella melitensis ATCC 23457 7678059 YP_002733700.1 CDS BMEA_A2093 NC_012441.1 1976222 1977433 D hypothetical protein 1976222..1977433 Brucella melitensis ATCC 23457 7678060 YP_002733701.1 CDS BMEA_A2094 NC_012441.1 1977412 1977669 D SirA family protein 1977412..1977669 Brucella melitensis ATCC 23457 7678061 YP_002733702.1 CDS BMEA_A2095 NC_012441.1 1977687 1978859 R cobalamin synthesis protein P47K complement(1977687..1978859) Brucella melitensis ATCC 23457 7678062 YP_002733703.1 CDS BMEA_A2096 NC_012441.1 1978861 1979973 R serine-type D-Ala-D-Ala carboxypeptidase complement(1978861..1979973) Brucella melitensis ATCC 23457 7678063 YP_002733704.1 CDS BMEA_A2098 NC_012441.1 1981431 1981565 D hypothetical protein 1981431..1981565 Brucella melitensis ATCC 23457 7678065 YP_002733705.1 CDS BMEA_A2100 NC_012441.1 1981633 1982397 R glucose 1-dehydrogenase complement(1981633..1982397) Brucella melitensis ATCC 23457 7678067 YP_002733706.1 CDS BMEA_A2102 NC_012441.1 1983037 1983432 D hypothetical protein 1983037..1983432 Brucella melitensis ATCC 23457 7678069 YP_002733707.1 CDS BMEA_A2104 NC_012441.1 1985134 1985898 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1985134..1985898) Brucella melitensis ATCC 23457 7678071 YP_002733708.1 CDS BMEA_A2105 NC_012441.1 1985895 1987379 R glucose-methanol-choline oxidoreductase complement(1985895..1987379) Brucella melitensis ATCC 23457 7678072 YP_002733709.1 CDS BMEA_A2106 NC_012441.1 1987392 1988912 R aldehyde dehydrogenase complement(1987392..1988912) Brucella melitensis ATCC 23457 7678073 YP_002733710.1 CDS BMEA_A2107 NC_012441.1 1988906 1989682 R enoyl-CoA hydratase/isomerase complement(1988906..1989682) Brucella melitensis ATCC 23457 7678074 YP_002733711.1 CDS BMEA_A2108 NC_012441.1 1989684 1991174 R coenzyme A transferase complement(1989684..1991174) Brucella melitensis ATCC 23457 7678075 YP_002733712.1 CDS BMEA_A2109 NC_012441.1 1991180 1992181 R hypothetical protein complement(1991180..1992181) Brucella melitensis ATCC 23457 7678076 YP_002733713.1 CDS BMEA_A2110 NC_012441.1 1992160 1993218 R alanine racemase complement(1992160..1993218) Brucella melitensis ATCC 23457 7678077 YP_002733714.1 CDS BMEA_A2111 NC_012441.1 1993469 1994638 D hypothetical protein 1993469..1994638 Brucella melitensis ATCC 23457 7678078 YP_002733715.1 CDS BMEA_A2112 NC_012441.1 1994672 1995694 R alkanal monooxygenase subunit alpha complement(1994672..1995694) Brucella melitensis ATCC 23457 7678079 YP_002733716.1 CDS BMEA_A2113 NC_012441.1 1995691 1995900 R hypothetical protein complement(1995691..1995900) Brucella melitensis ATCC 23457 7678080 YP_002733717.1 CDS BMEA_A2114 NC_012441.1 1995963 1996928 D hypothetical protein 1995963..1996928 Brucella melitensis ATCC 23457 7678081 YP_002733718.1 CDS BMEA_A2115 NC_012441.1 1997436 1997570 R hypothetical protein complement(1997436..1997570) Brucella melitensis ATCC 23457 7678082 YP_002733719.1 CDS BMEA_A2116 NC_012441.1 1997572 1998456 D hypothetical protein 1997572..1998456 Brucella melitensis ATCC 23457 7678083 YP_002733720.1 CDS BMEA_A2117 NC_012441.1 1998453 1999247 D ABC transporter 1998453..1999247 Brucella melitensis ATCC 23457 7678084 YP_002733721.1 CDS holA NC_012441.1 1999409 2000452 D required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1999409..2000452 Brucella melitensis ATCC 23457 7678085 YP_002733722.1 CDS BMEA_A2119 NC_012441.1 2000546 2001427 R ParB-like partition protein complement(2000546..2001427) Brucella melitensis ATCC 23457 7678086 YP_002733723.1 CDS BMEA_A2120 NC_012441.1 2001471 2002268 R hypothetical protein complement(2001471..2002268) Brucella melitensis ATCC 23457 7678087 YP_002733724.1 CDS gidB NC_012441.1 2002321 2002962 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(2002321..2002962) Brucella melitensis ATCC 23457 7678088 YP_002733725.1 CDS gidA NC_012441.1 2002959 2004869 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(2002959..2004869) Brucella melitensis ATCC 23457 7678089 YP_002733726.1 CDS trmE NC_012441.1 2005096 2006424 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(2005096..2006424) Brucella melitensis ATCC 23457 7678090 YP_002733727.1 CDS rho NC_012441.1 2008553 2009818 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(2008553..2009818) Brucella melitensis ATCC 23457 7678092 YP_002733728.1 CDS BMEA_A2126 NC_012441.1 2010200 2010736 R hypothetical protein complement(2010200..2010736) Brucella melitensis ATCC 23457 7678093 YP_002733729.1 CDS hemE NC_012441.1 2010733 2011758 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(2010733..2011758) Brucella melitensis ATCC 23457 7678094 YP_002733730.1 CDS BMEA_A2128 NC_012441.1 2011991 2012104 R hypothetical protein complement(2011991..2012104) Brucella melitensis ATCC 23457 7678095 YP_002733731.1 CDS BMEA_A2129 NC_012441.1 2012211 2013050 D hypothetical protein 2012211..2013050 Brucella melitensis ATCC 23457 7678096 YP_002733732.1 CDS maf NC_012441.1 2013047 2013646 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2013047..2013646 Brucella melitensis ATCC 23457 7678097 YP_002733733.1 CDS aroE NC_012441.1 2013639 2014508 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 2013639..2014508 Brucella melitensis ATCC 23457 7678098 YP_002733734.1 CDS coaE NC_012441.1 2014505 2015107 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2014505..2015107 Brucella melitensis ATCC 23457 7678099 YP_002733735.1 CDS dnaQ NC_012441.1 2015149 2015853 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 2015149..2015853 Brucella melitensis ATCC 23457 7678100 YP_002733736.1 CDS secB NC_012441.1 2015912 2016403 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(2015912..2016403) Brucella melitensis ATCC 23457 7678101 YP_002733737.1 CDS BMEA_A2135 NC_012441.1 2016523 2017020 R F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein complement(2016523..2017020) Brucella melitensis ATCC 23457 7678102 YP_002733738.1 CDS BMEA_A2136 NC_012441.1 2017237 2017932 D import inner membrane translocase subunit Tim44 2017237..2017932 Brucella melitensis ATCC 23457 7678103 YP_002733739.1 CDS BMEA_A2137 NC_012441.1 2017996 2019105 D MltA domain-containing protein 2017996..2019105 Brucella melitensis ATCC 23457 7678104 YP_002733740.1 CDS BMEA_A2138 NC_012441.1 2019111 2019713 D Smr protein/MutS2 2019111..2019713 Brucella melitensis ATCC 23457 7678105 YP_002733741.1 CDS BMEA_A2139 NC_012441.1 2019710 2020090 D XRE family transcriptional regulator 2019710..2020090 Brucella melitensis ATCC 23457 7678106 YP_002733742.1 CDS BMEA_A2140 NC_012441.1 2020099 2021118 R hypothetical protein complement(2020099..2021118) Brucella melitensis ATCC 23457 7678107 YP_002733743.1 CDS hslU NC_012441.1 2021265 2022569 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(2021265..2022569) Brucella melitensis ATCC 23457 7678108 YP_002733744.1 CDS BMEA_A2142 NC_012441.1 2022643 2023197 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(2022643..2023197) Brucella melitensis ATCC 23457 7678109 YP_002733745.1 CDS BMEA_A2143 NC_012441.1 2023494 2024102 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2023494..2024102 Brucella melitensis ATCC 23457 7678110 YP_002733746.1 CDS BMEA_A2144 NC_012441.1 2024214 2024723 D hypothetical protein 2024214..2024723 Brucella melitensis ATCC 23457 7678111 YP_002733747.1 CDS hisH NC_012441.1 2024726 2025376 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2024726..2025376 Brucella melitensis ATCC 23457 7678112 YP_002733748.1 CDS hisA NC_012441.1 2025381 2026112 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2025381..2026112 Brucella melitensis ATCC 23457 7678113 YP_002733749.1 CDS hisF NC_012441.1 2026109 2026894 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2026109..2026894 Brucella melitensis ATCC 23457 7678114 YP_002733750.1 CDS hisE NC_012441.1 2027030 2027353 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2027030..2027353 Brucella melitensis ATCC 23457 7678115 YP_002733751.1 CDS coaA NC_012441.1 2027368 2028336 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2027368..2028336 Brucella melitensis ATCC 23457 7678116 YP_002733752.1 CDS BMEA_A2150 NC_012441.1 2028399 2028836 R peptidyl-tRNA hydrolase domain-containing protein complement(2028399..2028836) Brucella melitensis ATCC 23457 7678117 YP_002733753.1 CDS BMEA_A2153 NC_012441.1 2030959 2031678 D transcriptional regulator ChvI 2030959..2031678 Brucella melitensis ATCC 23457 7678119 YP_002733754.1 CDS BMEA_A2154 NC_012441.1 2031789 2033594 D sensor protein chvG 2031789..2033594 Brucella melitensis ATCC 23457 7678120 YP_002733755.1 CDS BMEA_A2155 NC_012441.1 2033620 2034099 D HPr kinase 2033620..2034099 Brucella melitensis ATCC 23457 7678121 YP_002733756.1 CDS BMEA_A2156 NC_012441.1 2034351 2034752 D PTS system fructose subfamily transporter subunit IIA 2034351..2034752 Brucella melitensis ATCC 23457 7678122 YP_002733757.1 CDS BMEA_A2157 NC_012441.1 2034756 2035070 D HPr family phosphocarrier 2034756..2035070 Brucella melitensis ATCC 23457 7678123 YP_002733758.1 CDS BMEA_A2158 NC_012441.1 2035134 2035451 D hypothetical protein 2035134..2035451 Brucella melitensis ATCC 23457 7678124 YP_002733759.1 CDS ahcY NC_012441.1 2035448 2036848 D catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2035448..2036848 Brucella melitensis ATCC 23457 7678125 YP_002733760.1 CDS BMEA_A2160 NC_012441.1 2037233 2039812 D histidine kinase 2037233..2039812 Brucella melitensis ATCC 23457 7678126 YP_002733761.1 CDS BMEA_A2161 NC_012441.1 2039821 2041362 D hypothetical protein 2039821..2041362 Brucella melitensis ATCC 23457 7678127 YP_002733762.1 CDS BMEA_A2162 NC_012441.1 2041349 2042068 D nucleotidyl transferase 2041349..2042068 Brucella melitensis ATCC 23457 7678128 YP_002733763.1 CDS addB NC_012441.1 2042083 2045241 D double-strand break repair protein AddB 2042083..2045241 Brucella melitensis ATCC 23457 7678129 YP_002733764.1 CDS addA NC_012441.1 2045238 2048780 D double-strand break repair helicase AddA 2045238..2048780 Brucella melitensis ATCC 23457 7678130 YP_002733765.1 CDS trx NC_012441.1 2048962 2049285 D thioredoxin 2048962..2049285 Brucella melitensis ATCC 23457 7678131 YP_002733766.1 CDS folC NC_012441.1 2049499 2050827 R bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC complement(2049499..2050827) Brucella melitensis ATCC 23457 7678132 YP_002733767.1 CDS accD NC_012441.1 2050830 2051735 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2050830..2051735) Brucella melitensis ATCC 23457 7678133 YP_002733768.1 CDS trpA NC_012441.1 2051796 2052635 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(2051796..2052635) Brucella melitensis ATCC 23457 7678134 YP_002733769.1 CDS BMEA_A2169 NC_012441.1 2052632 2053099 R hypothetical protein complement(2052632..2053099) Brucella melitensis ATCC 23457 7678135 YP_002733770.1 CDS trpB NC_012441.1 2053102 2054322 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(2053102..2054322) Brucella melitensis ATCC 23457 7678136 YP_002733771.1 CDS BMEA_A2171 NC_012441.1 2054342 2055010 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(2054342..2055010) Brucella melitensis ATCC 23457 7678137 YP_002733772.1 CDS BMEA_A2172 NC_012441.1 2055049 2055684 R hypothetical protein complement(2055049..2055684) Brucella melitensis ATCC 23457 7678138 YP_002733773.1 CDS BMEA_A2173 NC_012441.1 2055681 2056442 R hypothetical protein complement(2055681..2056442) Brucella melitensis ATCC 23457 7678139 YP_002733774.1 CDS BMEA_A2174 NC_012441.1 2056551 2056913 R hypothetical protein complement(2056551..2056913) Brucella melitensis ATCC 23457 7678140 YP_002733775.1 CDS BMEA_A2175 NC_012441.1 2057180 2058331 R benzoate transporter complement(2057180..2058331) Brucella melitensis ATCC 23457 7678141 YP_002733776.1 CDS BMEA_A2176 NC_012441.1 2058345 2059136 R hypothetical protein complement(2058345..2059136) Brucella melitensis ATCC 23457 7678142 YP_002733777.1 CDS BMEA_A2177 NC_012441.1 2059568 2059972 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2059568..2059972 Brucella melitensis ATCC 23457 7678143 YP_002733778.1 CDS BMEA_A2178 NC_012441.1 2060101 2060715 D nickel-cobalt-cadmium resistance protein NccN 2060101..2060715 Brucella melitensis ATCC 23457 7678144 YP_002733779.1 CDS rpmI NC_012441.1 2060982 2061182 D 50S ribosomal protein L35 2060982..2061182 Brucella melitensis ATCC 23457 7678145 YP_002733780.1 CDS rplT NC_012441.1 2061210 2061614 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2061210..2061614 Brucella melitensis ATCC 23457 7676664 YP_002733781.1 CDS BMEA_A2181 NC_012441.1 2061713 2062555 D hypothetical protein 2061713..2062555 Brucella melitensis ATCC 23457 7676665 YP_002733782.1 CDS pheS NC_012441.1 2062643 2063752 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2062643..2063752 Brucella melitensis ATCC 23457 7676666 YP_002733783.1 CDS pheT NC_012441.1 2063774 2066188 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2063774..2066188 Brucella melitensis ATCC 23457 7676667 YP_002733784.1 CDS BMEA_A2184 NC_012441.1 2066258 2067244 D oxidoreductase 2066258..2067244 Brucella melitensis ATCC 23457 7676668 YP_002733785.1 CDS dnaK NC_012441.1 2067470 2069383 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2067470..2069383 Brucella melitensis ATCC 23457 7676669 YP_002733786.1 CDS BMEA_A2187 NC_012441.1 2069401 2069595 R hypothetical protein complement(2069401..2069595) Brucella melitensis ATCC 23457 7676670 YP_002733787.1 CDS dnaJ NC_012441.1 2069629 2070762 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2069629..2070762 Brucella melitensis ATCC 23457 7676671 YP_002733788.1 CDS BMEA_A2189 NC_012441.1 2070883 2071482 D phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamine N-methyltransferase 2070883..2071482 Brucella melitensis ATCC 23457 7676672 YP_002733789.1 CDS pyrF NC_012441.1 2071692 2072408 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2071692..2072408 Brucella melitensis ATCC 23457 7676673 YP_002733790.1 CDS BMEA_A2191 NC_012441.1 2072457 2072744 D hypothetical protein 2072457..2072744 Brucella melitensis ATCC 23457 7676674 YP_002733791.1 CDS BMEA_A2192 NC_012441.1 2072782 2073969 R regucalcin complement(2072782..2073969) Brucella melitensis ATCC 23457 7676675 YP_002733792.1 CDS gshB NC_012441.1 2073905 2074843 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2073905..2074843 Brucella melitensis ATCC 23457 7676676 YP_002733793.1 CDS BMEA_A2194 NC_012441.1 2074929 2076485 D Mg chelatase-like protein 2074929..2076485 Brucella melitensis ATCC 23457 7676677 YP_002733794.1 CDS BMEA_A2195 NC_012441.1 2076534 2077154 R transglutaminase complement(2076534..2077154) Brucella melitensis ATCC 23457 7676678 YP_002733795.1 CDS rlpA NC_012441.1 2077602 2077958 R rare lipoprotein A complement(2077602..2077958) Brucella melitensis ATCC 23457 7676679 YP_002733796.1 CDS BMEA_A2197 NC_012441.1 2078117 2078335 D hypothetical protein 2078117..2078335 Brucella melitensis ATCC 23457 7676680 YP_002733797.1 CDS BMEA_A2198 NC_012441.1 2078568 2078918 D hypothetical protein 2078568..2078918 Brucella melitensis ATCC 23457 7676681 YP_002733798.1 CDS BMEA_A2199 NC_012441.1 2079073 2080119 D hypothetical protein 2079073..2080119 Brucella melitensis ATCC 23457 7676682 YP_002733799.1 CDS pstC NC_012441.1 2080261 2081751 D phosphate ABC transporter permease 2080261..2081751 Brucella melitensis ATCC 23457 7676683 YP_002733800.1 CDS pstA NC_012441.1 2081751 2083061 D phosphate ABC transporter permease 2081751..2083061 Brucella melitensis ATCC 23457 7676684 YP_002733801.1 CDS pstB NC_012441.1 2083078 2083899 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2083078..2083899 Brucella melitensis ATCC 23457 7676685 YP_002733802.1 CDS phoU NC_012441.1 2083965 2084687 D phosphate transport system regulatory protein PhoU 2083965..2084687 Brucella melitensis ATCC 23457 7676686 YP_002733803.1 CDS phoB NC_012441.1 2084805 2085491 D phosphate regulon transcriptional regulatory protein PhoB 2084805..2085491 Brucella melitensis ATCC 23457 7676687 YP_002733804.1 CDS BMEA_A2205 NC_012441.1 2085847 2086005 R hypothetical protein complement(2085847..2086005) Brucella melitensis ATCC 23457 7676688 YP_002733805.1 CDS BMEA_A2206 NC_012441.1 2086077 2087057 D cell wall hydrolase SleB 2086077..2087057 Brucella melitensis ATCC 23457 7676689 YP_002733806.1 CDS BMEA_A2207 NC_012441.1 2087167 2087490 R lipoprotein complement(2087167..2087490) Brucella melitensis ATCC 23457 7676690 YP_002733807.1 CDS BMEA_A2208 NC_012441.1 2087567 2088820 D aminopeptidase T 2087567..2088820 Brucella melitensis ATCC 23457 7676691 YP_002733808.1 CDS BMEA_A2209 NC_012441.1 2088981 2089478 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(2088981..2089478) Brucella melitensis ATCC 23457 7676692 YP_002733809.1 CDS BMEA_A2210 NC_012441.1 2089761 2090450 D peptidase M22 glycoprotease 2089761..2090450 Brucella melitensis ATCC 23457 7676693 YP_002733810.1 CDS BMEA_A2211 NC_012441.1 2090455 2090955 D ribosomal-protein-alanine acetyltransferase 2090455..2090955 Brucella melitensis ATCC 23457 7676694 YP_002733811.1 CDS BMEA_A2212 NC_012441.1 2090952 2091755 D 1-acyl-sn-glycerol-3-phosphate acyltransferase 2090952..2091755 Brucella melitensis ATCC 23457 7676695 YP_002733812.1 CDS BMEA_A2213 NC_012441.1 2091813 2093216 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2091813..2093216 Brucella melitensis ATCC 23457 7676696 YP_002733813.1 CDS BMEA_A2214 NC_012441.1 2093453 2094436 D hypothetical protein 2093453..2094436 Brucella melitensis ATCC 23457 7676697 YP_002733814.1 CDS BMEA_A2215 NC_012441.1 2094572 2095078 D hypothetical protein 2094572..2095078 Brucella melitensis ATCC 23457 7676698 YP_002733815.1 CDS BMEA_A2216 NC_012441.1 2095081 2096199 D hemolysin C 2095081..2096199 Brucella melitensis ATCC 23457 7676699 YP_002733816.1 CDS lnt NC_012441.1 2096196 2097794 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2096196..2097794 Brucella melitensis ATCC 23457 7676700 YP_002733817.1 CDS BMEA_A2219 NC_012441.1 2097941 2098354 D XRE family transcriptional regulator 2097941..2098354 Brucella melitensis ATCC 23457 7676701 YP_002733818.1 CDS metK NC_012441.1 2098581 2099846 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2098581..2099846 Brucella melitensis ATCC 23457 7676702 YP_002733819.1 CDS BMEA_A2221 NC_012441.1 2099855 2100556 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2099855..2100556 Brucella melitensis ATCC 23457 7676703 YP_002733820.1 CDS BMEA_A2222 NC_012441.1 2100736 2101395 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2100736..2101395 Brucella melitensis ATCC 23457 7676704 YP_002733821.1 CDS nusA NC_012441.1 2101448 2103061 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2101448..2103061 Brucella melitensis ATCC 23457 7676705 YP_002733822.1 CDS BMEA_A2224 NC_012441.1 2103444 2104046 D hypothetical protein 2103444..2104046 Brucella melitensis ATCC 23457 7676706 YP_002733823.1 CDS infB NC_012441.1 2104184 2107063 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2104184..2107063 Brucella melitensis ATCC 23457 7676707 YP_002733824.1 CDS rbfA NC_012441.1 2107329 2107781 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2107329..2107781 Brucella melitensis ATCC 23457 7676708 YP_002733825.1 CDS truB NC_012441.1 2107785 2108759 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2107785..2108759 Brucella melitensis ATCC 23457 7676709 YP_002733826.1 CDS rpsO NC_012441.1 2108930 2109199 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2108930..2109199 Brucella melitensis ATCC 23457 7676710 YP_002733827.1 CDS BMEA_A2229 NC_012441.1 2109483 2111627 D polynucleotide phosphorylase/polyadenylase 2109483..2111627 Brucella melitensis ATCC 23457 7676711 YP_002733828.1 CDS BMEA_A2231 NC_012441.1 2112809 2113627 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(2112809..2113627) Brucella melitensis ATCC 23457 7676713 YP_002733829.1 CDS BMEA_A2232 NC_012441.1 2113642 2114865 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2113642..2114865) Brucella melitensis ATCC 23457 7676714 YP_002733830.1 CDS fabA NC_012441.1 2115031 2115549 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(2115031..2115549) Brucella melitensis ATCC 23457 7676715 YP_002733831.1 CDS BMEA_A2234 NC_012441.1 2115796 2116239 D ferric uptake regulation protein 2115796..2116239 Brucella melitensis ATCC 23457 7676716 YP_002733832.1 CDS BMEA_A2235 NC_012441.1 2116405 2117184 D lipoprotein, YaeC family protein 2116405..2117184 Brucella melitensis ATCC 23457 7676717 YP_002733833.1 CDS BMEA_A2236 NC_012441.1 2117229 2117774 R hypothetical protein complement(2117229..2117774) Brucella melitensis ATCC 23457 7676718 YP_002733834.1 CDS BMEA_A2237 NC_012441.1 2118125 2119129 D glycerate dehydrogenase 2118125..2119129 Brucella melitensis ATCC 23457 7676719 YP_002733835.1 CDS BMEA_A2238 NC_012441.1 2119154 2119855 R dihydrolipoyllysine-residue acetyltransferase complement(2119154..2119855) Brucella melitensis ATCC 23457 7676720 YP_002733836.1 CDS BMEA_A2239 NC_012441.1 2119877 2120749 R dipeptidyl-peptidase 6 complement(2119877..2120749) Brucella melitensis ATCC 23457 7676721 YP_002733837.1 CDS BMEA_A2240 NC_012441.1 2120746 2121096 R MarR family transcriptional regulator complement(2120746..2121096) Brucella melitensis ATCC 23457 7676722 YP_002733838.1 CDS BMEA_A2241 NC_012441.1 2121171 2122553 R cytosol aminopeptidase complement(2121171..2122553) Brucella melitensis ATCC 23457 7676723 YP_002733839.1 CDS BMEA_A2242 NC_012441.1 2122657 2122956 D hypothetical protein 2122657..2122956 Brucella melitensis ATCC 23457 7676724 YP_002733840.1 CDS BMEA_A2243 NC_012441.1 2122713 2122892 R hypothetical protein complement(2122713..2122892) Brucella melitensis ATCC 23457 7676725 YP_002733841.1 CDS mutM NC_012441.1 2123112 2123993 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2123112..2123993 Brucella melitensis ATCC 23457 7676726 YP_002733842.1 CDS BMEA_A2245 NC_012441.1 2124120 2124893 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2124120..2124893 Brucella melitensis ATCC 23457 7676727 YP_002733843.1 CDS rpsT NC_012441.1 2125229 2125495 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2125229..2125495 Brucella melitensis ATCC 23457 7676728 YP_002733844.1 CDS BMEA_B0004 NC_012442.1 155 1348 D replication initiation protein RepC 155..1348 Brucella melitensis ATCC 23457 7670527 YP_002733845.1 CDS BMEA_B0005 NC_012442.1 1413 1562 R hypothetical protein complement(1413..1562) Brucella melitensis ATCC 23457 7670528 YP_002733846.1 CDS BMEA_B0006 NC_012442.1 1551 1814 D hypothetical protein 1551..1814 Brucella melitensis ATCC 23457 7670529 YP_002733847.1 CDS rbsK NC_012442.1 2092 3033 D ribokinase 2092..3033 Brucella melitensis ATCC 23457 7670530 YP_002733848.1 CDS BMEA_B0008 NC_012442.1 3110 4108 R Inosine-uridine preferring nucleoside hydrolase complement(3110..4108) Brucella melitensis ATCC 23457 7670531 YP_002733849.1 CDS BMEA_B0009 NC_012442.1 4131 5042 R inner-membrane translocator complement(4131..5042) Brucella melitensis ATCC 23457 7670532 YP_002733850.1 CDS BMEA_B0010 NC_012442.1 5039 6118 R hypothetical protein complement(5039..6118) Brucella melitensis ATCC 23457 7670533 YP_002733851.1 CDS BMEA_B0011 NC_012442.1 6180 7751 R Galactose/methyl galactoside import ATP-binding protein mglA complement(6180..7751) Brucella melitensis ATCC 23457 7670534 YP_002733852.1 CDS BMEA_B0013 NC_012442.1 9104 9712 D hypothetical protein 9104..9712 Brucella melitensis ATCC 23457 7670536 YP_002733853.1 CDS BMEA_B0015 NC_012442.1 10398 11174 R catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(10398..11174) Brucella melitensis ATCC 23457 7670538 YP_002733854.1 CDS BMEA_B0016 NC_012442.1 11174 12046 R putative isochorismatase complement(11174..12046) Brucella melitensis ATCC 23457 7670539 YP_002733855.1 CDS entE NC_012442.1 12098 13717 R bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E complement(12098..13717) Brucella melitensis ATCC 23457 7670540 YP_002733856.1 CDS BMEA_B0018 NC_012442.1 13824 14999 R isochorismate synthase complement(13824..14999) Brucella melitensis ATCC 23457 7670541 YP_002733857.1 CDS BMEA_B0019 NC_012442.1 15071 16480 D Linear gramicidin synthetase subunit B 15071..16480 Brucella melitensis ATCC 23457 7670542 YP_002733858.1 CDS BMEA_B0020 NC_012442.1 16528 17316 R oxidoreductase, molybdopterin-binding complement(16528..17316) Brucella melitensis ATCC 23457 7670543 YP_002733859.1 CDS BMEA_B0021 NC_012442.1 17313 18122 R HupC/HyaC/HydC family protein complement(17313..18122) Brucella melitensis ATCC 23457 7670544 YP_002733860.1 CDS BMEA_B0022 NC_012442.1 18185 18454 R pentapeptide MXKDX repeat protein complement(18185..18454) Brucella melitensis ATCC 23457 7670545 YP_002733861.1 CDS BMEA_B0023 NC_012442.1 18639 19163 D RNA polymerase sigma factor, sigma-70 family protein 18639..19163 Brucella melitensis ATCC 23457 7670546 YP_002733862.1 CDS BMEA_B0024 NC_012442.1 19138 19788 D hypothetical protein 19138..19788 Brucella melitensis ATCC 23457 7670547 YP_002733863.1 CDS BMEA_B0025 NC_012442.1 19834 20574 R GntR family transcriptional regulator complement(19834..20574) Brucella melitensis ATCC 23457 7670548 YP_002733864.1 CDS BMEA_B0026 NC_012442.1 20692 22107 D Leu/Ile/Val-binding protein family protein 20692..22107 Brucella melitensis ATCC 23457 7670549 YP_002733865.1 CDS BMEA_B0027 NC_012442.1 22149 23138 D inner-membrane translocator 22149..23138 Brucella melitensis ATCC 23457 7670550 YP_002733866.1 CDS BMEA_B0028 NC_012442.1 23142 24362 D inner-membrane translocator 23142..24362 Brucella melitensis ATCC 23457 7670551 YP_002733867.1 CDS BMEA_B0029 NC_012442.1 24362 25114 D ABC transporter 24362..25114 Brucella melitensis ATCC 23457 7670552 YP_002733868.1 CDS BMEA_B0030 NC_012442.1 25114 25830 D ABC transporter 25114..25830 Brucella melitensis ATCC 23457 7670553 YP_002733869.1 CDS BMEA_B0031 NC_012442.1 25882 26364 D hypothetical protein 25882..26364 Brucella melitensis ATCC 23457 7670554 YP_002733870.1 CDS BMEA_B0032 NC_012442.1 26368 27105 D short-chain dehydrogenase/reductase SDR 26368..27105 Brucella melitensis ATCC 23457 7670555 YP_002733871.1 CDS BMEA_B0033 NC_012442.1 27354 27875 D cyclopentanol dehydrogenase 27354..27875 Brucella melitensis ATCC 23457 7670556 YP_002733872.1 CDS BMEA_B0035 NC_012442.1 30192 31457 D branched-chain alpha-keto acid dehydrogenase subunit E2 30192..31457 Brucella melitensis ATCC 23457 7670558 YP_002733873.1 CDS BMEA_B0036 NC_012442.1 31558 32343 D Shikimate dehydrogenase 31558..32343 Brucella melitensis ATCC 23457 7670559 YP_002733874.1 CDS BMEA_B0037 NC_012442.1 32623 32916 D hypothetical protein 32623..32916 Brucella melitensis ATCC 23457 7670560 YP_002733875.1 CDS BMEA_B0038 NC_012442.1 32870 33151 R hypothetical protein complement(32870..33151) Brucella melitensis ATCC 23457 7670561 YP_002733876.1 CDS mgtA NC_012442.1 33269 35986 D magnesium-translocating P-type ATPase 33269..35986 Brucella melitensis ATCC 23457 7670562 YP_002733877.1 CDS BMEA_B0040 NC_012442.1 36071 36421 D hypothetical protein 36071..36421 Brucella melitensis ATCC 23457 7670563 YP_002733878.1 CDS BMEA_B0041 NC_012442.1 36552 36755 D hypothetical protein 36552..36755 Brucella melitensis ATCC 23457 7670564 YP_002733879.1 CDS BMEA_B0042 NC_012442.1 36757 37473 D MgtC-magnesium transport family protein 36757..37473 Brucella melitensis ATCC 23457 7670565 YP_002733880.1 CDS BMEA_B0043 NC_012442.1 37548 38618 D sensor nodulation protein 37548..38618 Brucella melitensis ATCC 23457 7670566 YP_002733881.1 CDS BMEA_B0044 NC_012442.1 38615 39253 D C4-dicarboxylate transport transcriptional regulatory protein dctR 38615..39253 Brucella melitensis ATCC 23457 7670567 YP_002733882.1 CDS BMEA_B0046 NC_012442.1 39639 40001 R hypothetical protein complement(39639..40001) Brucella melitensis ATCC 23457 7670569 YP_002733883.1 CDS BMEA_B0047 NC_012442.1 40320 41210 D N-formylglutamate amidohydrolase 40320..41210 Brucella melitensis ATCC 23457 7670570 YP_002733884.1 CDS BMEA_B0048 NC_012442.1 41372 42148 D histidinol-phosphate phosphatase 41372..42148 Brucella melitensis ATCC 23457 7670571 YP_002733885.1 CDS BMEA_B0049 NC_012442.1 42199 43194 R Lysophospholipase complement(42199..43194) Brucella melitensis ATCC 23457 7670572 YP_002733886.1 CDS BMEA_B0050 NC_012442.1 43234 43449 R hypothetical protein complement(43234..43449) Brucella melitensis ATCC 23457 7670573 YP_002733887.1 CDS BMEA_B0051 NC_012442.1 43544 43942 R hypothetical protein complement(43544..43942) Brucella melitensis ATCC 23457 7670574 YP_002733888.1 CDS BMEA_B0053 NC_012442.1 43994 44203 D hypothetical protein 43994..44203 Brucella melitensis ATCC 23457 7670575 YP_002733889.1 CDS BMEA_B0054 NC_012442.1 44176 44427 D hypothetical protein 44176..44427 Brucella melitensis ATCC 23457 7670576 YP_002733890.1 CDS BMEA_B0055 NC_012442.1 44506 44976 D Small heat shock protein hspD 44506..44976 Brucella melitensis ATCC 23457 7670577 YP_002733891.1 CDS BMEA_B0056 NC_012442.1 45114 46163 R Low specificity L-threonine aldolase complement(45114..46163) Brucella melitensis ATCC 23457 7670578 YP_002733892.1 CDS BMEA_B0057 NC_012442.1 46432 46716 R hypothetical protein complement(46432..46716) Brucella melitensis ATCC 23457 7670579 YP_002733893.1 CDS BMEA_B0058 NC_012442.1 46806 51557 D glutamate synthase, large subunit 46806..51557 Brucella melitensis ATCC 23457 7670580 YP_002733894.1 CDS gltD NC_012442.1 51639 53093 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 51639..53093 Brucella melitensis ATCC 23457 7670581 YP_002733895.1 CDS BMEA_B0060 NC_012442.1 53138 54541 R amino acid permease-associated protein complement(53138..54541) Brucella melitensis ATCC 23457 7670582 YP_002733896.1 CDS BMEA_B0061 NC_012442.1 54759 55910 R hypothetical protein complement(54759..55910) Brucella melitensis ATCC 23457 7670583 YP_002733897.1 CDS BMEA_B0062 NC_012442.1 56161 56679 R TraQ protein complement(56161..56679) Brucella melitensis ATCC 23457 7670584 YP_002733898.1 CDS BMEA_B0063 NC_012442.1 56825 57913 R P-type DNA transfer ATPase VirB11 complement(56825..57913) Brucella melitensis ATCC 23457 7670585 YP_002733899.1 CDS BMEA_B0064 NC_012442.1 57894 59045 R type IV secretion system protein virB10 complement(57894..59045) Brucella melitensis ATCC 23457 7670586 YP_002733900.1 CDS BMEA_B0065 NC_012442.1 59042 59911 R P-type conjugative transfer protein VirB9 complement(59042..59911) Brucella melitensis ATCC 23457 7670587 YP_002733901.1 CDS BMEA_B0066 NC_012442.1 59908 60627 R type IV secretion system protein virB8 complement(59908..60627) Brucella melitensis ATCC 23457 7670588 YP_002733902.1 CDS BMEA_B0067 NC_012442.1 60630 60803 R TraI protein complement(60630..60803) Brucella melitensis ATCC 23457 7670589 YP_002733903.1 CDS BMEA_B0068 NC_012442.1 60967 62010 R protein virB6 complement(60967..62010) Brucella melitensis ATCC 23457 7670590 YP_002733904.1 CDS BMEA_B0069 NC_012442.1 62194 62910 R P-type DNA transfer protein VirB5 complement(62194..62910) Brucella melitensis ATCC 23457 7670591 YP_002733905.1 CDS BMEA_B0070 NC_012442.1 62915 65410 R type IV secretion/conjugal transfer ATPase, VirB4 family protein complement(62915..65410) Brucella melitensis ATCC 23457 7670592 YP_002733906.1 CDS BMEA_B0071 NC_012442.1 65410 65760 R type IV secretory pathway VirB3 family protein complement(65410..65760) Brucella melitensis ATCC 23457 7670593 YP_002733907.1 CDS BMEA_B0072 NC_012442.1 65774 66091 R conjugal transfer protein TrbC complement(65774..66091) Brucella melitensis ATCC 23457 7670594 YP_002733908.1 CDS BMEA_B0073 NC_012442.1 66527 67243 R Lytic transglycosylase catalytic complement(66527..67243) Brucella melitensis ATCC 23457 7670595 YP_002733909.1 CDS BMEA_B0074 NC_012442.1 67747 68985 R lytic murein transglycosylase complement(67747..68985) Brucella melitensis ATCC 23457 7670596 YP_002733910.1 CDS galU NC_012442.1 69385 70278 D UTP-glucose-1-phosphate uridylyltransferase 69385..70278 Brucella melitensis ATCC 23457 7670597 YP_002733911.1 CDS BMEA_B0076 NC_012442.1 70331 71869 R hypothetical protein complement(70331..71869) Brucella melitensis ATCC 23457 7670598 YP_002733912.1 CDS BMEA_B0077 NC_012442.1 72010 73011 D sugar isomerase, KpsF/GutQ family protein 72010..73011 Brucella melitensis ATCC 23457 7670599 YP_002733913.1 CDS BMEA_B0078 NC_012442.1 73150 73617 R hypothetical protein complement(73150..73617) Brucella melitensis ATCC 23457 7670600 YP_002733914.1 CDS BMEA_B0079 NC_012442.1 73638 74624 R band 7 protein complement(73638..74624) Brucella melitensis ATCC 23457 7670601 YP_002733915.1 CDS hemH NC_012442.1 74757 75815 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(74757..75815) Brucella melitensis ATCC 23457 7670602 YP_002733916.1 CDS BMEA_B0081 NC_012442.1 75953 76333 R hypothetical protein complement(75953..76333) Brucella melitensis ATCC 23457 7670603 YP_002733917.1 CDS BMEA_B0083 NC_012442.1 78032 78712 R hypothetical protein complement(78032..78712) Brucella melitensis ATCC 23457 7670605 YP_002733918.1 CDS pabB NC_012442.1 78646 79815 R catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase complement(78646..79815) Brucella melitensis ATCC 23457 7670606 YP_002733919.1 CDS BMEA_B0085 NC_012442.1 79825 81687 R oligoendopeptidase, pepF/M3 family protein complement(79825..81687) Brucella melitensis ATCC 23457 7670607 YP_002733920.1 CDS BMEA_B0086 NC_012442.1 82035 83525 D two component, sigma54 specific, transcriptional regulator, Fis family protein 82035..83525 Brucella melitensis ATCC 23457 7670608 YP_002733921.1 CDS BMEA_B0087 NC_012442.1 83866 85779 D hypothetical protein 83866..85779 Brucella melitensis ATCC 23457 7670609 YP_002733922.1 CDS eda NC_012442.1 85845 86483 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(85845..86483) Brucella melitensis ATCC 23457 7670610 YP_002733923.1 CDS BMEA_B0089 NC_012442.1 86642 87253 R hypothetical protein complement(86642..87253) Brucella melitensis ATCC 23457 7670611 YP_002733924.1 CDS BMEA_B0090 NC_012442.1 87384 88301 D rhodanese family protein 87384..88301 Brucella melitensis ATCC 23457 7670612 YP_002733925.1 CDS BMEA_B0091 NC_012442.1 88336 88542 D hypothetical protein 88336..88542 Brucella melitensis ATCC 23457 7670613 YP_002733926.1 CDS modA NC_012442.1 88582 89337 D molybdate ABC transporter substrate-binding protein 88582..89337 Brucella melitensis ATCC 23457 7670614 YP_002733927.1 CDS modB NC_012442.1 89348 90034 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 89348..90034 Brucella melitensis ATCC 23457 7670615 YP_002733928.1 CDS modC NC_012442.1 90031 91110 D molybdate ABC transporter ATP-binding protein 90031..91110 Brucella melitensis ATCC 23457 7670616 YP_002733929.1 CDS BMEA_B0095 NC_012442.1 91180 91857 D GCN5-related N-acetyltransferase 91180..91857 Brucella melitensis ATCC 23457 7670617 YP_002733930.1 CDS BMEA_B0096 NC_012442.1 91850 92053 D hypothetical protein 91850..92053 Brucella melitensis ATCC 23457 7670618 YP_002733931.1 CDS BMEA_B0097 NC_012442.1 92145 92300 D hypothetical protein 92145..92300 Brucella melitensis ATCC 23457 7670619 YP_002733932.1 CDS BMEA_B0098 NC_012442.1 92995 94098 R high-affinity nickel-transporter complement(92995..94098) Brucella melitensis ATCC 23457 7670620 YP_002733933.1 CDS BMEA_B0099 NC_012442.1 94098 94802 R hypothetical protein complement(94098..94802) Brucella melitensis ATCC 23457 7670621 YP_002733934.1 CDS BMEA_B0100 NC_012442.1 94842 95735 R LysR family transcriptional regulator complement(94842..95735) Brucella melitensis ATCC 23457 7670622 YP_002733935.1 CDS BMEA_B0101 NC_012442.1 95739 96944 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(95739..96944) Brucella melitensis ATCC 23457 7670623 YP_002733936.1 CDS BMEA_B0103 NC_012442.1 97529 98662 D Lysine/ornithine decarboxylase 97529..98662 Brucella melitensis ATCC 23457 7670624 YP_002733937.1 CDS BMEA_B0104 NC_012442.1 98738 100456 R lipopolysaccharide biosynthesis protein complement(98738..100456) Brucella melitensis ATCC 23457 7670625 YP_002733938.1 CDS BMEA_B0105 NC_012442.1 100473 100610 R hypothetical protein complement(100473..100610) Brucella melitensis ATCC 23457 7670626 YP_002733939.1 CDS BMEA_B0106 NC_012442.1 100582 101484 R hypothetical protein complement(100582..101484) Brucella melitensis ATCC 23457 7670627 YP_002733940.1 CDS BMEA_B0107 NC_012442.1 101442 102203 R WecB/TagA/CpsF family protein glycosyl transferase complement(101442..102203) Brucella melitensis ATCC 23457 7670628 YP_002733941.1 CDS BMEA_B0108 NC_012442.1 102204 103394 R hypothetical protein complement(102204..103394) Brucella melitensis ATCC 23457 7670629 YP_002733942.1 CDS BMEA_B0110 NC_012442.1 103530 104522 D glycosyl transferase family 2 protein 103530..104522 Brucella melitensis ATCC 23457 7670630 YP_002733943.1 CDS BMEA_B0111 NC_012442.1 104491 105816 D O-antigen polymerase 104491..105816 Brucella melitensis ATCC 23457 7670631 YP_002733944.1 CDS BMEA_B0113 NC_012442.1 106963 108012 R trans-1,2-dihydrobenzene-1,2-diol dehydrogenase complement(106963..108012) Brucella melitensis ATCC 23457 7670633 YP_002733945.1 CDS gnd NC_012442.1 108329 109738 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 108329..109738 Brucella melitensis ATCC 23457 7670634 YP_002733946.1 CDS BMEA_B0115 NC_012442.1 109834 110895 R polyamine ABC transporter ATP-binding protein complement(109834..110895) Brucella melitensis ATCC 23457 7670635 YP_002733947.1 CDS BMEA_B0116 NC_012442.1 110901 111719 R hypothetical protein complement(110901..111719) Brucella melitensis ATCC 23457 7670636 YP_002733948.1 CDS BMEA_B0117 NC_012442.1 111716 112609 R hypothetical protein complement(111716..112609) Brucella melitensis ATCC 23457 7670637 YP_002733949.1 CDS BMEA_B0118 NC_012442.1 112818 113921 R family 1 extracellular solute-binding protein complement(112818..113921) Brucella melitensis ATCC 23457 7670638 YP_002733950.1 CDS BMEA_B0119 NC_012442.1 114330 115907 R drug resistance transporter, EmrB/QacA subfamily protein complement(114330..115907) Brucella melitensis ATCC 23457 7670639 YP_002733951.1 CDS BMEA_B0120 NC_012442.1 116000 117241 R secretion protein HlyD family protein complement(116000..117241) Brucella melitensis ATCC 23457 7670640 YP_002733952.1 CDS BMEA_B0121 NC_012442.1 117342 118085 D TetR family transcriptional regulator 117342..118085 Brucella melitensis ATCC 23457 7670641 YP_002733953.1 CDS BMEA_B0122 NC_012442.1 118359 119138 D regulatory protein LuxR 118359..119138 Brucella melitensis ATCC 23457 7670642 YP_002733954.1 CDS BMEA_B0123 NC_012442.1 119207 119626 R hypothetical protein complement(119207..119626) Brucella melitensis ATCC 23457 7670643 YP_002733955.1 CDS flhB NC_012442.1 119746 120816 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(119746..120816) Brucella melitensis ATCC 23457 7670644 YP_002733956.1 CDS fliN NC_012442.1 121822 122142 R flagellar motor switch protein FliN complement(121822..122142) Brucella melitensis ATCC 23457 7670646 YP_002733957.1 CDS BMEA_B0127 NC_012442.1 122166 122627 R hypothetical protein complement(122166..122627) Brucella melitensis ATCC 23457 7670647 YP_002733958.1 CDS BMEA_B0128 NC_012442.1 122608 123558 R Flagellar motor switch protein fliM complement(122608..123558) Brucella melitensis ATCC 23457 7670648 YP_002733959.1 CDS BMEA_B0129 NC_012442.1 123560 124432 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(123560..124432) Brucella melitensis ATCC 23457 7670649 YP_002733960.1 CDS BMEA_B0130 NC_012442.1 124578 125366 D hypothetical protein 124578..125366 Brucella melitensis ATCC 23457 7670650 YP_002733961.1 CDS flgF NC_012442.1 125366 126097 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgF 125366..126097 Brucella melitensis ATCC 23457 7670651 YP_002733962.1 CDS fliI NC_012442.1 126094 127455 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 126094..127455 Brucella melitensis ATCC 23457 7670652 YP_002733963.1 CDS BMEA_B0134 NC_012442.1 127779 128057 D hypothetical protein 127779..128057 Brucella melitensis ATCC 23457 7670653 YP_002733964.1 CDS BMEA_B0135 NC_012442.1 128082 129059 R bacitracin transport permease BCRC complement(128082..129059) Brucella melitensis ATCC 23457 7670654 YP_002733965.1 CDS BMEA_B0136 NC_012442.1 129047 129202 D hypothetical protein 129047..129202 Brucella melitensis ATCC 23457 7670655 YP_002733966.1 CDS BMEA_B0137 NC_012442.1 129357 129575 R hypothetical protein complement(129357..129575) Brucella melitensis ATCC 23457 7670656 YP_002733967.1 CDS BMEA_B0138 NC_012442.1 129603 129992 D hypothetical protein 129603..129992 Brucella melitensis ATCC 23457 7670657 YP_002733968.1 CDS BMEA_B0139 NC_012442.1 129989 130969 D glycosyl transferase family 2 protein 129989..130969 Brucella melitensis ATCC 23457 7670658 YP_002733969.1 CDS BMEA_B0140 NC_012442.1 130950 131702 D YdjC family protein 130950..131702 Brucella melitensis ATCC 23457 7670659 YP_002733970.1 CDS BMEA_B0141 NC_012442.1 131699 133135 D dolichyl-phosphate-mannose-protein mannosyltransferase family protein 131699..133135 Brucella melitensis ATCC 23457 7670660 YP_002733971.1 CDS BMEA_B0142 NC_012442.1 133337 134335 D helix-turn-helix- domain containing protein 133337..134335 Brucella melitensis ATCC 23457 7670661 YP_002733972.1 CDS BMEA_B0143 NC_012442.1 134691 135128 D putative transcriptional regulator protein 134691..135128 Brucella melitensis ATCC 23457 7670662 YP_002733973.1 CDS BMEA_B0144 NC_012442.1 135322 136623 R tartrate transporter complement(135322..136623) Brucella melitensis ATCC 23457 7670663 YP_002733974.1 CDS BMEA_B0145 NC_012442.1 136649 137281 R putative aldolase complement(136649..137281) Brucella melitensis ATCC 23457 7670664 YP_002733975.1 CDS BMEA_B0146 NC_012442.1 137307 138272 R NAD-dependent epimerase/dehydratase complement(137307..138272) Brucella melitensis ATCC 23457 7670665 YP_002733976.1 CDS BMEA_B0147 NC_012442.1 138272 139063 R DeoR family transcriptional regulator complement(138272..139063) Brucella melitensis ATCC 23457 7670666 YP_002733977.1 CDS BMEA_B0148 NC_012442.1 139060 139845 R AP endonuclease, family 2 complement(139060..139845) Brucella melitensis ATCC 23457 7670667 YP_002733978.1 CDS BMEA_B0149 NC_012442.1 139845 141119 R hypothetical protein complement(139845..141119) Brucella melitensis ATCC 23457 7670668 YP_002733979.1 CDS BMEA_B0150 NC_012442.1 141121 142029 R 2-hydroxy-3-oxopropionate reductase complement(141121..142029) Brucella melitensis ATCC 23457 7670669 YP_002733980.1 CDS BMEA_B0151 NC_012442.1 142179 142316 D hypothetical protein 142179..142316 Brucella melitensis ATCC 23457 7670670 YP_002733981.1 CDS flgB NC_012442.1 142393 142773 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal body rod protein FlgB 142393..142773 Brucella melitensis ATCC 23457 7670671 YP_002733982.1 CDS flgC NC_012442.1 142776 143198 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 142776..143198 Brucella melitensis ATCC 23457 7670672 YP_002733983.1 CDS fliE NC_012442.1 143198 143533 D forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar hook-basal body protein FliE 143198..143533 Brucella melitensis ATCC 23457 7670673 YP_002733984.1 CDS flgG NC_012442.1 143619 144407 D makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; flagellar basal body rod protein FlgG 143619..144407 Brucella melitensis ATCC 23457 7670674 YP_002733985.1 CDS flgA NC_012442.1 144419 144901 D required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body P-ring biosynthesis protein FlgA 144419..144901 Brucella melitensis ATCC 23457 7670675 YP_002733986.1 CDS flgI NC_012442.1 144937 146271 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 144937..146271 Brucella melitensis ATCC 23457 7670676 YP_002733987.1 CDS BMEA_B0158 NC_012442.1 146268 146828 D hypothetical protein 146268..146828 Brucella melitensis ATCC 23457 7670677 YP_002733988.1 CDS flgH NC_012442.1 146837 147553 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 146837..147553 Brucella melitensis ATCC 23457 7670678 YP_002733989.1 CDS BMEA_B0160 NC_012442.1 147566 148057 D flagellar basal body-associated protein FliL 147566..148057 Brucella melitensis ATCC 23457 7670679 YP_002733990.1 CDS fliP NC_012442.1 148054 148794 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 148054..148794 Brucella melitensis ATCC 23457 7670680 YP_002733991.1 CDS BMEA_B0162 NC_012442.1 148889 149368 D hypothetical protein 148889..149368 Brucella melitensis ATCC 23457 7670681 YP_002733992.1 CDS BMEA_B0163 NC_012442.1 149313 149696 D hypothetical protein 149313..149696 Brucella melitensis ATCC 23457 7670682 YP_002733993.1 CDS BMEA_B0164 NC_012442.1 149892 150776 R putative transcription regulator protein complement(149892..150776) Brucella melitensis ATCC 23457 7670683 YP_002733994.1 CDS BMEA_B0165 NC_012442.1 150828 150959 D hypothetical protein 150828..150959 Brucella melitensis ATCC 23457 7670684 YP_002733995.1 CDS BMEA_B0167 NC_012442.1 150956 152173 D L-carnitine dehydratase/bile acid-inducible protein F 150956..152173 Brucella melitensis ATCC 23457 7670685 YP_002733996.1 CDS BMEA_B0168 NC_012442.1 152241 153077 D hypothetical protein 152241..153077 Brucella melitensis ATCC 23457 7670686 YP_002733997.1 CDS BMEA_B0169 NC_012442.1 153071 153895 D HpcH/HpaI aldolase 153071..153895 Brucella melitensis ATCC 23457 7670687 YP_002733998.1 CDS BMEA_B0170 NC_012442.1 153928 154080 D hypothetical protein 153928..154080 Brucella melitensis ATCC 23457 7670688 YP_002733999.1 CDS BMEA_B0171 NC_012442.1 154345 154923 D cytochrome B561 154345..154923 Brucella melitensis ATCC 23457 7670689 YP_002734000.1 CDS BMEA_B0172 NC_012442.1 155713 156117 D arylsulfatase 155713..156117 Brucella melitensis ATCC 23457 7670690 YP_002734001.1 CDS BMEA_B0174 NC_012442.1 159475 159870 D cytochrome c2 159475..159870 Brucella melitensis ATCC 23457 7670692 YP_002734002.1 CDS BMEA_B0175 NC_012442.1 160094 160333 R hypothetical protein complement(160094..160333) Brucella melitensis ATCC 23457 7670693 YP_002734003.1 CDS BMEA_B0176 NC_012442.1 160763 160900 D hypothetical protein 160763..160900 Brucella melitensis ATCC 23457 7670694 YP_002734004.1 CDS BMEA_B0177 NC_012442.1 160978 161790 R GntR family transcriptional regulator complement(160978..161790) Brucella melitensis ATCC 23457 7670695 YP_002734005.1 CDS BMEA_B0178 NC_012442.1 161912 162832 R hypothetical protein complement(161912..162832) Brucella melitensis ATCC 23457 7670696 YP_002734006.1 CDS BMEA_B0179 NC_012442.1 162992 163111 R hypothetical protein complement(162992..163111) Brucella melitensis ATCC 23457 7670697 YP_002734007.1 CDS BMEA_B0180 NC_012442.1 163183 164679 D FAD binding domain-containing protein 163183..164679 Brucella melitensis ATCC 23457 7670698 YP_002734008.1 CDS BMEA_B0181 NC_012442.1 164695 165927 D FAD linked oxidase domain-containing protein 164695..165927 Brucella melitensis ATCC 23457 7670699 YP_002734009.1 CDS BMEA_B0182 NC_012442.1 165932 167221 D hypothetical protein 165932..167221 Brucella melitensis ATCC 23457 7670700 YP_002734010.1 CDS BMEA_B0183 NC_012442.1 167444 168271 R 2,5-diketo-D-gluconic acid reductase A complement(167444..168271) Brucella melitensis ATCC 23457 7670701 YP_002734011.1 CDS BMEA_B0184 NC_012442.1 168547 169281 R ErfK/YbiS/YcfS/YnhG family protein complement(168547..169281) Brucella melitensis ATCC 23457 7670702 YP_002734012.1 CDS BMEA_B0185 NC_012442.1 169521 170177 D DNA-3-methyladenine glycosylase I 169521..170177 Brucella melitensis ATCC 23457 7670703 YP_002734013.1 CDS BMEA_B0186 NC_012442.1 170296 170913 D Lysine exporter protein LYSE/YGGA 170296..170913 Brucella melitensis ATCC 23457 7670704 YP_002734014.1 CDS hisS NC_012442.1 171024 172532 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 171024..172532 Brucella melitensis ATCC 23457 7670705 YP_002734015.1 CDS hisZ NC_012442.1 172541 173671 D May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 172541..173671 Brucella melitensis ATCC 23457 7670706 YP_002734016.1 CDS hisG NC_012442.1 173668 174363 D short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 173668..174363 Brucella melitensis ATCC 23457 7670707 YP_002734017.1 CDS gluP NC_012442.1 174436 175674 R glucose/galactose transporter complement(174436..175674) Brucella melitensis ATCC 23457 7670708 YP_002734018.1 CDS BMEA_B0191 NC_012442.1 175960 176361 R DoxX family protein complement(175960..176361) Brucella melitensis ATCC 23457 7670709 YP_002734019.1 CDS fumC NC_012442.1 176464 177855 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(176464..177855) Brucella melitensis ATCC 23457 7670710 YP_002734020.1 CDS BMEA_B0193 NC_012442.1 178006 178293 R hypothetical protein complement(178006..178293) Brucella melitensis ATCC 23457 7670711 YP_002734021.1 CDS BMEA_B0194 NC_012442.1 178590 178796 R hypothetical protein complement(178590..178796) Brucella melitensis ATCC 23457 7670712 YP_002734022.1 CDS groEL NC_012442.1 178940 180580 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(178940..180580) Brucella melitensis ATCC 23457 7670713 YP_002734023.1 CDS groES NC_012442.1 180671 180967 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(180671..180967) Brucella melitensis ATCC 23457 7670714 YP_002734024.1 CDS BMEA_B0197 NC_012442.1 181087 181227 D hypothetical protein 181087..181227 Brucella melitensis ATCC 23457 7670715 YP_002734025.1 CDS BMEA_B0198 NC_012442.1 181280 181384 R hypothetical protein complement(181280..181384) Brucella melitensis ATCC 23457 7670716 YP_002734026.1 CDS BMEA_B0199 NC_012442.1 181445 182296 D HAD-superfamily hydrolase 181445..182296 Brucella melitensis ATCC 23457 7670717 YP_002734027.1 CDS ribF NC_012442.1 182384 183373 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 182384..183373 Brucella melitensis ATCC 23457 7670718 YP_002734028.1 CDS ileS NC_012442.1 183717 186635 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 183717..186635 Brucella melitensis ATCC 23457 7670719 YP_002734029.1 CDS BMEA_B0202 NC_012442.1 186827 187498 D hypothetical protein 186827..187498 Brucella melitensis ATCC 23457 7670720 YP_002734030.1 CDS BMEA_B0203 NC_012442.1 187843 188403 D cytochrome B561 187843..188403 Brucella melitensis ATCC 23457 7670721 YP_002734031.1 CDS BMEA_B0204 NC_012442.1 188457 188930 R cytidine and deoxycytidylate deaminase family protein complement(188457..188930) Brucella melitensis ATCC 23457 7670722 YP_002734032.1 CDS BMEA_B0205 NC_012442.1 189020 190816 D hypothetical protein 189020..190816 Brucella melitensis ATCC 23457 7670723 YP_002734033.1 CDS BMEA_B0207 NC_012442.1 190797 191360 D methyltransferase 190797..191360 Brucella melitensis ATCC 23457 7670724 YP_002734034.1 CDS BMEA_B0209 NC_012442.1 194366 195247 D patatin 194366..195247 Brucella melitensis ATCC 23457 7670726 YP_002734035.1 CDS BMEA_B0210 NC_012442.1 195260 197167 R potassium efflux system protein complement(195260..197167) Brucella melitensis ATCC 23457 7670727 YP_002734036.1 CDS BMEA_B0211 NC_012442.1 197306 198649 D peptidase U62 modulator of DNA gyrase 197306..198649 Brucella melitensis ATCC 23457 7670728 YP_002734037.1 CDS BMEA_B0212 NC_012442.1 198636 199445 D inositol monophosphatase 198636..199445 Brucella melitensis ATCC 23457 7670729 YP_002734038.1 CDS BMEA_B0213 NC_012442.1 199484 199735 D hypothetical protein 199484..199735 Brucella melitensis ATCC 23457 7670730 YP_002734039.1 CDS BMEA_B0214 NC_012442.1 199766 200542 D hypothetical protein 199766..200542 Brucella melitensis ATCC 23457 7670731 YP_002734040.1 CDS BMEA_B0215 NC_012442.1 200539 201879 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 200539..201879 Brucella melitensis ATCC 23457 7670732 YP_002734041.1 CDS lpxK NC_012442.1 201882 202907 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 201882..202907 Brucella melitensis ATCC 23457 7670733 YP_002734042.1 CDS BMEA_B0217 NC_012442.1 202921 203157 R hypothetical protein complement(202921..203157) Brucella melitensis ATCC 23457 7670734 YP_002734043.1 CDS mutL NC_012442.1 203255 205126 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(203255..205126) Brucella melitensis ATCC 23457 7670735 YP_002734044.1 CDS BMEA_B0220 NC_012442.1 206690 207844 R acyl-CoA dehydrogenase complement(206690..207844) Brucella melitensis ATCC 23457 7670737 YP_002734045.1 CDS BMEA_B0221 NC_012442.1 207901 208755 R putative transcriptional regulator complement(207901..208755) Brucella melitensis ATCC 23457 7670738 YP_002734046.1 CDS BMEA_B0222 NC_012442.1 209015 209776 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 209015..209776 Brucella melitensis ATCC 23457 7670739 YP_002734047.1 CDS BMEA_B0224 NC_012442.1 211522 212763 D L-carnitine dehydrogenase 211522..212763 Brucella melitensis ATCC 23457 7670741 YP_002734048.1 CDS BMEA_B0225 NC_012442.1 212747 214021 R NADH oxidase complement(212747..214021) Brucella melitensis ATCC 23457 7670742 YP_002734049.1 CDS BMEA_B0226 NC_012442.1 214107 214571 D mercuric resistance operon regulatory protein 214107..214571 Brucella melitensis ATCC 23457 7670743 YP_002734050.1 CDS BMEA_B0227 NC_012442.1 214617 215324 R ThiJ/PfpI family protein complement(214617..215324) Brucella melitensis ATCC 23457 7670744 YP_002734051.1 CDS BMEA_B0228 NC_012442.1 215555 216895 R sensor histidine kinase complement(215555..216895) Brucella melitensis ATCC 23457 7670745 YP_002734052.1 CDS BMEA_B0229 NC_012442.1 216895 217572 R DNA-binding response regulator complement(216895..217572) Brucella melitensis ATCC 23457 7670746 YP_002734053.1 CDS BMEA_B0230 NC_012442.1 217700 217864 R hypothetical protein complement(217700..217864) Brucella melitensis ATCC 23457 7670747 YP_002734054.1 CDS BMEA_B0231 NC_012442.1 217836 218108 D hypothetical protein 217836..218108 Brucella melitensis ATCC 23457 7670748 YP_002734055.1 CDS BMEA_B0232 NC_012442.1 218276 218746 D hypothetical protein 218276..218746 Brucella melitensis ATCC 23457 7670749 YP_002734056.1 CDS BMEA_B0233 NC_012442.1 218757 220961 D oxidoreductase FAD-binding 218757..220961 Brucella melitensis ATCC 23457 7670750 YP_002734057.1 CDS BMEA_B0234 NC_012442.1 220942 221919 D thiamine biosynthesis lipoprotein ApbE 220942..221919 Brucella melitensis ATCC 23457 7670751 YP_002734058.1 CDS BMEA_B0235 NC_012442.1 221962 223137 R GAF/GGDEF domain-containing protein complement(221962..223137) Brucella melitensis ATCC 23457 7670752 YP_002734059.1 CDS BMEA_B0238 NC_012442.1 224287 224427 D hypothetical protein 224287..224427 Brucella melitensis ATCC 23457 7670754 YP_002734060.1 CDS BMEA_B0239 NC_012442.1 224527 225228 D GntR family transcriptional regulator 224527..225228 Brucella melitensis ATCC 23457 7670755 YP_002734061.1 CDS BMEA_B0240 NC_012442.1 225329 226291 D dihydrodipicolinate synthetase 225329..226291 Brucella melitensis ATCC 23457 7670756 YP_002734062.1 CDS BMEA_B0241 NC_012442.1 226354 227391 R malate/L-sulfolactate dehydrogenase complement(226354..227391) Brucella melitensis ATCC 23457 7670757 YP_002734063.1 CDS BMEA_B0242 NC_012442.1 227510 227608 R hypothetical protein complement(227510..227608) Brucella melitensis ATCC 23457 7670758 YP_002734064.1 CDS BMEA_B0243 NC_012442.1 227628 228896 D hypothetical protein 227628..228896 Brucella melitensis ATCC 23457 7670759 YP_002734065.1 CDS BMEA_B0245 NC_012442.1 229434 229589 R hypothetical protein complement(229434..229589) Brucella melitensis ATCC 23457 7670761 YP_002734066.1 CDS BMEA_B0247 NC_012442.1 229693 230262 D cytochrome c oxidase subunit 3 229693..230262 Brucella melitensis ATCC 23457 7670762 YP_002734067.1 CDS BMEA_B0248 NC_012442.1 230270 230548 D hypothetical protein 230270..230548 Brucella melitensis ATCC 23457 7670763 YP_002734068.1 CDS BMEA_B0249 NC_012442.1 230708 231160 D Nitric oxide reductase subunit C 230708..231160 Brucella melitensis ATCC 23457 7670764 YP_002734069.1 CDS BMEA_B0250 NC_012442.1 231186 232535 D Nitric oxide reductase subunit B 231186..232535 Brucella melitensis ATCC 23457 7670765 YP_002734070.1 CDS BMEA_B0251 NC_012442.1 232626 233438 D denitrification regulatory protein NirQ 232626..233438 Brucella melitensis ATCC 23457 7670766 YP_002734071.1 CDS BMEA_B0252 NC_012442.1 233450 235351 D protein norD 233450..235351 Brucella melitensis ATCC 23457 7670767 YP_002734072.1 CDS BMEA_B0253 NC_012442.1 235464 235826 D hypothetical protein 235464..235826 Brucella melitensis ATCC 23457 7670768 YP_002734073.1 CDS BMEA_B0254 NC_012442.1 235862 237229 D hypothetical protein 235862..237229 Brucella melitensis ATCC 23457 7670769 YP_002734074.1 CDS BMEA_B0255 NC_012442.1 237226 237753 D hypothetical protein 237226..237753 Brucella melitensis ATCC 23457 7670770 YP_002734075.1 CDS BMEA_B0256 NC_012442.1 237760 238086 D hypothetical protein 237760..238086 Brucella melitensis ATCC 23457 7670771 YP_002734076.1 CDS BMEA_B0257 NC_012442.1 238210 239385 D hypothetical protein 238210..239385 Brucella melitensis ATCC 23457 7670772 YP_002734077.1 CDS BMEA_B0258 NC_012442.1 239382 239966 D Isoprenylcysteine carboxyl methyltransferase 239382..239966 Brucella melitensis ATCC 23457 7670773 YP_002734078.1 CDS BMEA_B0259 NC_012442.1 239917 240615 D hypothetical protein 239917..240615 Brucella melitensis ATCC 23457 7670774 YP_002734079.1 CDS BMEA_B0260 NC_012442.1 240691 240840 D hypothetical protein 240691..240840 Brucella melitensis ATCC 23457 7670775 YP_002734080.1 CDS nirK NC_012442.1 240971 242101 D nitrite reductase, copper-containing 240971..242101 Brucella melitensis ATCC 23457 7670776 YP_002734081.1 CDS BMEA_B0262 NC_012442.1 242235 243155 D hypothetical protein 242235..243155 Brucella melitensis ATCC 23457 7670777 YP_002734082.1 CDS BMEA_B0263 NC_012442.1 243256 243951 D transcriptional activator protein fnrA 243256..243951 Brucella melitensis ATCC 23457 7670778 YP_002734083.1 CDS BMEA_B0264 NC_012442.1 244034 245089 D Ribitol operon repressor 244034..245089 Brucella melitensis ATCC 23457 7670779 YP_002734084.1 CDS BMEA_B0265 NC_012442.1 245270 245491 R hypothetical protein complement(245270..245491) Brucella melitensis ATCC 23457 7670780 YP_002734085.1 CDS BMEA_B0266 NC_012442.1 245490 246542 D multiple sugar-binding periplasmic receptor chvE 245490..246542 Brucella melitensis ATCC 23457 7670781 YP_002734086.1 CDS BMEA_B0267 NC_012442.1 246847 247713 D Ribose import ATP-binding protein rbsA 2 246847..247713 Brucella melitensis ATCC 23457 7670782 YP_002734087.1 CDS BMEA_B0268 NC_012442.1 247753 248949 D inner-membrane translocator 247753..248949 Brucella melitensis ATCC 23457 7670783 YP_002734088.1 CDS BMEA_B0269 NC_012442.1 249237 249965 D Ribitol 2-dehydrogenase 249237..249965 Brucella melitensis ATCC 23457 7670784 YP_002734089.1 CDS BMEA_B0270 NC_012442.1 249978 251582 D FGGY-family pentulose kinase 249978..251582 Brucella melitensis ATCC 23457 7670785 YP_002734090.1 CDS BMEA_B0271 NC_012442.1 251719 252384 R RES domain-containing protein complement(251719..252384) Brucella melitensis ATCC 23457 7670786 YP_002734091.1 CDS BMEA_B0272 NC_012442.1 252381 252857 R hypothetical protein complement(252381..252857) Brucella melitensis ATCC 23457 7670787 YP_002734092.1 CDS BMEA_B0273 NC_012442.1 253005 254912 R microcin-J25 export ATP-binding/permease mcjD complement(253005..254912) Brucella melitensis ATCC 23457 7670788 YP_002734093.1 CDS BMEA_B0274 NC_012442.1 255066 255224 R hypothetical protein complement(255066..255224) Brucella melitensis ATCC 23457 7670789 YP_002734094.1 CDS BMEA_B0275 NC_012442.1 255406 257769 D Regulatory protein nosR 255406..257769 Brucella melitensis ATCC 23457 7670790 YP_002734095.1 CDS BMEA_B0277 NC_012442.1 259715 261109 D copper-binding periplasmic protein 259715..261109 Brucella melitensis ATCC 23457 7670792 YP_002734096.1 CDS BMEA_B0278 NC_012442.1 261147 262097 D copper transport ATP-binding protein NosF 261147..262097 Brucella melitensis ATCC 23457 7670793 YP_002734097.1 CDS BMEA_B0279 NC_012442.1 262094 262924 D membrane protein NosY 262094..262924 Brucella melitensis ATCC 23457 7670794 YP_002734098.1 CDS BMEA_B0280 NC_012442.1 262921 263460 D NosL family protein 262921..263460 Brucella melitensis ATCC 23457 7670795 YP_002734099.1 CDS BMEA_B0282 NC_012442.1 264577 265275 D transcriptional regulator Crp/Fnr family protein 264577..265275 Brucella melitensis ATCC 23457 7670797 YP_002734100.1 CDS BMEA_B0283 NC_012442.1 265256 265855 D pseudoazurin 265256..265855 Brucella melitensis ATCC 23457 7670798 YP_002734101.1 CDS BMEA_B0284 NC_012442.1 265906 267147 D NnrS family protein 265906..267147 Brucella melitensis ATCC 23457 7670799 YP_002734102.1 CDS BMEA_B0285 NC_012442.1 267221 268261 R NMT1/THI5 like domain-containing protein complement(267221..268261) Brucella melitensis ATCC 23457 7670800 YP_002734103.1 CDS BMEA_B0286 NC_012442.1 268287 269078 R binding-protein-dependent transport systems inner membrane component complement(268287..269078) Brucella melitensis ATCC 23457 7670801 YP_002734104.1 CDS BMEA_B0288 NC_012442.1 269999 270250 D hypothetical protein 269999..270250 Brucella melitensis ATCC 23457 7670803 YP_002734105.1 CDS BMEA_B0289 NC_012442.1 270156 270299 R hypothetical protein complement(270156..270299) Brucella melitensis ATCC 23457 7670804 YP_002734106.1 CDS BMEA_B0290 NC_012442.1 270348 271280 R peptidase U32 complement(270348..271280) Brucella melitensis ATCC 23457 7670805 YP_002734107.1 CDS BMEA_B0291 NC_012442.1 271283 272260 R peptidase U32 complement(271283..272260) Brucella melitensis ATCC 23457 7670806 YP_002734108.1 CDS BMEA_B0292 NC_012442.1 272251 272775 R hypothetical protein complement(272251..272775) Brucella melitensis ATCC 23457 7670807 YP_002734109.1 CDS ubiD NC_012442.1 272889 274226 D UbiD family decarboxylase 272889..274226 Brucella melitensis ATCC 23457 7670808 YP_002734110.1 CDS BMEA_B0294 NC_012442.1 274223 274813 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 274223..274813 Brucella melitensis ATCC 23457 7670809 YP_002734111.1 CDS BMEA_B0295 NC_012442.1 274823 275359 R hypothetical protein complement(274823..275359) Brucella melitensis ATCC 23457 7670810 YP_002734112.1 CDS BMEA_B0296 NC_012442.1 275356 276291 R chaperone SurA complement(275356..276291) Brucella melitensis ATCC 23457 7670811 YP_002734113.1 CDS narI NC_012442.1 276297 277022 R respiratory nitrate reductase subunit gamma complement(276297..277022) Brucella melitensis ATCC 23457 7670812 YP_002734114.1 CDS narJ NC_012442.1 277033 277740 R nitrate reductase molybdenum cofactor assembly chaperone complement(277033..277740) Brucella melitensis ATCC 23457 7670813 YP_002734115.1 CDS narH NC_012442.1 277740 279278 R nitrate reductase subunit beta complement(277740..279278) Brucella melitensis ATCC 23457 7670814 YP_002734116.1 CDS BMEA_B0300 NC_012442.1 279275 283039 R nitrate reductase subunit alpha complement(279275..283039) Brucella melitensis ATCC 23457 7670815 YP_002734117.1 CDS narK NC_012442.1 282954 285758 R nitrite transporter complement(282954..285758) Brucella melitensis ATCC 23457 7670816 YP_002734118.1 CDS ftrB NC_012442.1 286048 286758 D upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrB 286048..286758 Brucella melitensis ATCC 23457 7670817 YP_002734119.1 CDS BMEA_B0303 NC_012442.1 286813 287829 R HTH-type transcriptional regulator RafR complement(286813..287829) Brucella melitensis ATCC 23457 7670818 YP_002734120.1 CDS BMEA_B0304 NC_012442.1 288180 289445 D family 1 extracellular solute-binding protein 288180..289445 Brucella melitensis ATCC 23457 7670819 YP_002734121.1 CDS BMEA_B0305 NC_012442.1 289522 290499 D binding-protein-dependent transport systems inner membrane component 289522..290499 Brucella melitensis ATCC 23457 7670820 YP_002734122.1 CDS BMEA_B0306 NC_012442.1 290502 291314 D binding-protein-dependent transport systems inner membrane component 290502..291314 Brucella melitensis ATCC 23457 7670821 YP_002734123.1 CDS BMEA_B0307 NC_012442.1 291321 292322 D ATP-binding transport protein SmoK 291321..292322 Brucella melitensis ATCC 23457 7670822 YP_002734124.1 CDS BMEA_B0308 NC_012442.1 292385 293170 D hypothetical protein 292385..293170 Brucella melitensis ATCC 23457 7670823 YP_002734125.1 CDS BMEA_B0309 NC_012442.1 293179 294225 D oxidoreductase domain-containing protein 293179..294225 Brucella melitensis ATCC 23457 7670824 YP_002734126.1 CDS BMEA_B0313 NC_012442.1 297025 297351 R hypothetical protein complement(297025..297351) Brucella melitensis ATCC 23457 7670827 YP_002734127.1 CDS nrdH NC_012442.1 297545 297766 D glutaredoxin-like protein NrdH 297545..297766 Brucella melitensis ATCC 23457 7670828 YP_002734128.1 CDS nrdI NC_012442.1 297780 298187 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 297780..298187 Brucella melitensis ATCC 23457 7670829 YP_002734129.1 CDS BMEA_B0316 NC_012442.1 298238 300379 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 298238..300379 Brucella melitensis ATCC 23457 7670830 YP_002734130.1 CDS nrdF NC_012442.1 300394 301383 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 300394..301383 Brucella melitensis ATCC 23457 7670831 YP_002734131.1 CDS BMEA_B0318 NC_012442.1 301552 301776 R hypothetical protein complement(301552..301776) Brucella melitensis ATCC 23457 7670832 YP_002734132.1 CDS BMEA_B0319 NC_012442.1 301987 302118 D hypothetical protein 301987..302118 Brucella melitensis ATCC 23457 7670833 YP_002734133.1 CDS minC NC_012442.1 302248 303009 D blocks the formation of polar Z-ring septums; septum formation inhibitor 302248..303009 Brucella melitensis ATCC 23457 7670834 YP_002734134.1 CDS minD NC_012442.1 303037 303852 D septum site-determining protein MinD 303037..303852 Brucella melitensis ATCC 23457 7670835 YP_002734135.1 CDS minE NC_012442.1 303849 304121 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 303849..304121 Brucella melitensis ATCC 23457 7670836 YP_002734136.1 CDS BMEA_B0323 NC_012442.1 304165 304332 D hypothetical protein 304165..304332 Brucella melitensis ATCC 23457 7670837 YP_002734137.1 CDS BMEA_B0325 NC_012442.1 304661 305053 R hypothetical protein complement(304661..305053) Brucella melitensis ATCC 23457 7670839 YP_002734138.1 CDS BMEA_B0327 NC_012442.1 306547 307614 D polyamine ABC transporter ATP-binding protein 306547..307614 Brucella melitensis ATCC 23457 7670841 YP_002734139.1 CDS BMEA_B0328 NC_012442.1 307548 308786 D binding-protein-dependent transport systems inner membrane component 307548..308786 Brucella melitensis ATCC 23457 7670842 YP_002734140.1 CDS BMEA_B0329 NC_012442.1 308789 309565 D binding-protein-dependent transport systems inner membrane component 308789..309565 Brucella melitensis ATCC 23457 7670843 YP_002734141.1 CDS BMEA_B0330 NC_012442.1 309877 310056 D hypothetical protein 309877..310056 Brucella melitensis ATCC 23457 7670844 YP_002734142.1 CDS BMEA_B0331 NC_012442.1 310053 310277 D hypothetical protein 310053..310277 Brucella melitensis ATCC 23457 7670845 YP_002734143.1 CDS BMEA_B0332 NC_012442.1 310514 311041 D hypothetical protein 310514..311041 Brucella melitensis ATCC 23457 7670846 YP_002734144.1 CDS BMEA_B0333 NC_012442.1 311184 311684 R hypothetical protein complement(311184..311684) Brucella melitensis ATCC 23457 7670847 YP_002734145.1 CDS BMEA_B0334 NC_012442.1 311681 314905 R hydrophobe/amphiphile efflux-1 family protein complement(311681..314905) Brucella melitensis ATCC 23457 7670848 YP_002734146.1 CDS BMEA_B0335 NC_012442.1 314909 316132 R RND family efflux transporter MFP subunit complement(314909..316132) Brucella melitensis ATCC 23457 7670849 YP_002734147.1 CDS BMEA_B0336 NC_012442.1 316318 316851 R membrane protein complement(316318..316851) Brucella melitensis ATCC 23457 7670850 YP_002734148.1 CDS BMEA_B0337 NC_012442.1 316926 317099 R hypothetical protein complement(316926..317099) Brucella melitensis ATCC 23457 7670851 YP_002734149.1 CDS BMEA_B0339 NC_012442.1 318874 320439 D glutamate/gamma-aminobutyrate antiporter 318874..320439 Brucella melitensis ATCC 23457 7670853 YP_002734150.1 CDS BMEA_B0341 NC_012442.1 321575 321919 D inactive form; acid-resistance protein 321575..321919 Brucella melitensis ATCC 23457 7670855 YP_002734151.1 CDS BMEA_B0342 NC_012442.1 322431 322682 D hypothetical protein 322431..322682 Brucella melitensis ATCC 23457 7670856 YP_002734152.1 CDS BMEA_B0343 NC_012442.1 322759 324351 R EAL complement(322759..324351) Brucella melitensis ATCC 23457 7670857 YP_002734153.1 CDS BMEA_B0344 NC_012442.1 324646 324912 R hypothetical protein complement(324646..324912) Brucella melitensis ATCC 23457 7670858 YP_002734154.1 CDS BMEA_B0346 NC_012442.1 326148 327563 R mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase complement(326148..327563) Brucella melitensis ATCC 23457 7670860 YP_002734155.1 CDS BMEA_B0347 NC_012442.1 327560 328993 R phosphomannomutase complement(327560..328993) Brucella melitensis ATCC 23457 7670861 YP_002734156.1 CDS BMEA_B0348 NC_012442.1 329113 330219 R peptidase S58 DmpA complement(329113..330219) Brucella melitensis ATCC 23457 7670862 YP_002734157.1 CDS BMEA_B0349 NC_012442.1 330243 331598 R chloride channel core protein complement(330243..331598) Brucella melitensis ATCC 23457 7670863 YP_002734158.1 CDS BMEA_B0350 NC_012442.1 331657 331818 R hypothetical protein complement(331657..331818) Brucella melitensis ATCC 23457 7670864 YP_002734159.1 CDS guaB NC_012442.1 331793 333286 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 331793..333286 Brucella melitensis ATCC 23457 7670865 YP_002734160.1 CDS BMEA_B0352 NC_012442.1 333446 334576 R cytochrome c class I complement(333446..334576) Brucella melitensis ATCC 23457 7670866 YP_002734161.1 CDS BMEA_B0353 NC_012442.1 334633 335586 R LysR family transcriptional regulator complement(334633..335586) Brucella melitensis ATCC 23457 7670867 YP_002734162.1 CDS BMEA_B0354 NC_012442.1 335756 337255 D catalase 335756..337255 Brucella melitensis ATCC 23457 7670868 YP_002734163.1 CDS BMEA_B0355 NC_012442.1 337350 337559 D hypothetical protein 337350..337559 Brucella melitensis ATCC 23457 7670869 YP_002734164.1 CDS BMEA_B0358 NC_012442.1 339968 340423 D hypothetical protein 339968..340423 Brucella melitensis ATCC 23457 7670872 YP_002734165.1 CDS BMEA_B0359 NC_012442.1 340420 341052 D Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 340420..341052 Brucella melitensis ATCC 23457 7670873 YP_002734166.1 CDS guaA NC_012442.1 341161 342723 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 341161..342723 Brucella melitensis ATCC 23457 7670874 YP_002734167.1 CDS BMEA_B0361 NC_012442.1 342809 342994 D hypothetical protein 342809..342994 Brucella melitensis ATCC 23457 7670875 YP_002734168.1 CDS BMEA_B0362 NC_012442.1 343106 343654 D hypothetical protein 343106..343654 Brucella melitensis ATCC 23457 7670876 YP_002734169.1 CDS BMEA_B0363 NC_012442.1 343658 344056 D hypothetical protein 343658..344056 Brucella melitensis ATCC 23457 7670877 YP_002734170.1 CDS BMEA_B0364 NC_012442.1 344063 344899 D Ferrous iron permease efeU 344063..344899 Brucella melitensis ATCC 23457 7670878 YP_002734171.1 CDS BMEA_B0365 NC_012442.1 344860 346293 D hypothetical protein 344860..346293 Brucella melitensis ATCC 23457 7670879 YP_002734172.1 CDS BMEA_B0366 NC_012442.1 346551 348929 R putative phosphoketolase complement(346551..348929) Brucella melitensis ATCC 23457 7670880 YP_002734173.1 CDS ackA NC_012442.1 348950 350155 R Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase complement(348950..350155) Brucella melitensis ATCC 23457 7670881 YP_002734174.1 CDS BMEA_B0368 NC_012442.1 350394 350555 D hypothetical protein 350394..350555 Brucella melitensis ATCC 23457 7670882 YP_002734175.1 CDS BMEA_B0369 NC_012442.1 350598 351761 D cytochrome P450 109 350598..351761 Brucella melitensis ATCC 23457 7670883 YP_002734176.1 CDS BMEA_B0370 NC_012442.1 351832 352509 R GntR family transcriptional regulator complement(351832..352509) Brucella melitensis ATCC 23457 7670884 YP_002734177.1 CDS BMEA_B0371 NC_012442.1 352567 352788 D hypothetical protein 352567..352788 Brucella melitensis ATCC 23457 7670885 YP_002734178.1 CDS BMEA_B0372 NC_012442.1 352781 353788 D quinone oxidoreductase, PIG3 family protein 352781..353788 Brucella melitensis ATCC 23457 7670886 YP_002734179.1 CDS BMEA_B0373 NC_012442.1 353872 355083 D Leu/Ile/Val-binding protein family protein 353872..355083 Brucella melitensis ATCC 23457 7670887 YP_002734180.1 CDS fabG NC_012442.1 358549 359346 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 358549..359346 Brucella melitensis ATCC 23457 7670889 YP_002734181.1 CDS BMEA_B0376 NC_012442.1 359351 360169 D Shikimate dehydrogenase 359351..360169 Brucella melitensis ATCC 23457 7670890 YP_002734182.1 CDS BMEA_B0377 NC_012442.1 360174 361808 D oxidoreductase, GMC family protein 360174..361808 Brucella melitensis ATCC 23457 7670891 YP_002734183.1 CDS BMEA_B0378 NC_012442.1 361833 363266 D Succinate-semialdehyde dehydrogenase NAD(P)+ 361833..363266 Brucella melitensis ATCC 23457 7670892 YP_002734184.1 CDS BMEA_B0379 NC_012442.1 363358 364521 D Leu/Ile/Val-binding protein family protein 363358..364521 Brucella melitensis ATCC 23457 7670893 YP_002734185.1 CDS BMEA_B0380 NC_012442.1 364584 365711 D alcohol dehydrogenase 1 364584..365711 Brucella melitensis ATCC 23457 7670894 YP_002734186.1 CDS BMEA_B0382 NC_012442.1 367961 368914 R oligopeptide ABC transporter ATP-binding protein complement(367961..368914) Brucella melitensis ATCC 23457 7670896 YP_002734187.1 CDS BMEA_B0383 NC_012442.1 368911 369927 R peptide ABC transporter ATPase complement(368911..369927) Brucella melitensis ATCC 23457 7670897 YP_002734188.1 CDS BMEA_B0384 NC_012442.1 369938 370855 R Dihydrodipicolinate synthase complement(369938..370855) Brucella melitensis ATCC 23457 7670898 YP_002734189.1 CDS BMEA_B0385 NC_012442.1 370875 371783 R binding-protein-dependent transport systems inner membrane component complement(370875..371783) Brucella melitensis ATCC 23457 7670899 YP_002734190.1 CDS BMEA_B0386 NC_012442.1 371749 372708 R ABC transporter permease complement(371749..372708) Brucella melitensis ATCC 23457 7670900 YP_002734191.1 CDS BMEA_B0387 NC_012442.1 372808 374391 R extracellular solute-binding protein complement(372808..374391) Brucella melitensis ATCC 23457 7670901 YP_002734192.1 CDS BMEA_B0388 NC_012442.1 374388 375116 R GntR family transcriptional regulator complement(374388..375116) Brucella melitensis ATCC 23457 7670902 YP_002734193.1 CDS BMEA_B0389 NC_012442.1 375276 376853 D N-acetylmannosamine-6-phosphate 2-epimerase 375276..376853 Brucella melitensis ATCC 23457 7670903 YP_002734194.1 CDS BMEA_B0390 NC_012442.1 376859 378043 D N-acetylneuraminic acid mutarotase 376859..378043 Brucella melitensis ATCC 23457 7670904 YP_002734195.1 CDS BMEA_B0391 NC_012442.1 378159 378419 D hypothetical protein 378159..378419 Brucella melitensis ATCC 23457 7670905 YP_002734196.1 CDS BMEA_B0392 NC_012442.1 378420 379178 R transcriptional regulator Crp/Fnr family protein complement(378420..379178) Brucella melitensis ATCC 23457 7670906 YP_002734197.1 CDS BMEA_B0393 NC_012442.1 379541 380308 D two component transcriptional regulator, LuxR family protein 379541..380308 Brucella melitensis ATCC 23457 7670907 YP_002734198.1 CDS BMEA_B0394 NC_012442.1 380345 382534 D lipopolysaccharide biosynthesis protein 380345..382534 Brucella melitensis ATCC 23457 7670908 YP_002734199.1 CDS BMEA_B0395 NC_012442.1 382544 383791 D plectin-1 382544..383791 Brucella melitensis ATCC 23457 7670909 YP_002734200.1 CDS gmd NC_012442.1 384859 385929 R GDP-mannose 4,6-dehydratase complement(384859..385929) Brucella melitensis ATCC 23457 7670911 YP_002734201.1 CDS BMEA_B0398 NC_012442.1 386103 387443 D putative glycosyltransferase wbjE 386103..387443 Brucella melitensis ATCC 23457 7670912 YP_002734202.1 CDS BMEA_B0399 NC_012442.1 387464 388699 D glycosyl transferase group 1 protein 387464..388699 Brucella melitensis ATCC 23457 7670913 YP_002734203.1 CDS BMEA_B0400 NC_012442.1 388696 389892 D glycosyl transferase group 1 protein 388696..389892 Brucella melitensis ATCC 23457 7670914 YP_002734204.1 CDS BMEA_B0401 NC_012442.1 389963 390685 R outer membrane protein Omp31 complement(389963..390685) Brucella melitensis ATCC 23457 7670915 YP_002734205.1 CDS BMEA_B0402 NC_012442.1 391082 391696 R chloramphenicol acetyltransferase complement(391082..391696) Brucella melitensis ATCC 23457 7670916 YP_002734206.1 CDS BMEA_B0403 NC_012442.1 391708 392970 R hypothetical protein complement(391708..392970) Brucella melitensis ATCC 23457 7670917 YP_002734207.1 CDS BMEA_B0404 NC_012442.1 392967 393584 R hypothetical protein complement(392967..393584) Brucella melitensis ATCC 23457 7670918 YP_002734208.1 CDS BMEA_B0405 NC_012442.1 393581 394462 R Lipopolysaccharide core biosynthesis glycosyltransferase kdtX complement(393581..394462) Brucella melitensis ATCC 23457 7670919 YP_002734209.1 CDS BMEA_B0406 NC_012442.1 394459 395580 R phospho-N-acetylmuramoyl-pentapeptide- transferase complement(394459..395580) Brucella melitensis ATCC 23457 7670920 YP_002734210.1 CDS BMEA_B0407 NC_012442.1 395684 395791 R hypothetical protein complement(395684..395791) Brucella melitensis ATCC 23457 7670921 YP_002734211.1 CDS BMEA_B0408 NC_012442.1 395873 397366 D polysaccharide biosynthesis protein 395873..397366 Brucella melitensis ATCC 23457 7670922 YP_002734212.1 CDS BMEA_B0410 NC_012442.1 398351 399592 R polysaccharide pyruvyl transferase complement(398351..399592) Brucella melitensis ATCC 23457 7670923 YP_002734213.1 CDS BMEA_B0412 NC_012442.1 401125 402486 D catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; glutamate-1-semialdehyde 2,1-aminomutase 401125..402486 Brucella melitensis ATCC 23457 7670925 YP_002734214.1 CDS BMEA_B0413 NC_012442.1 402465 403799 D hypothetical protein 402465..403799 Brucella melitensis ATCC 23457 7670926 YP_002734215.1 CDS BMEA_B0414 NC_012442.1 403920 404981 D NAD-dependent epimerase/dehydratase 403920..404981 Brucella melitensis ATCC 23457 7670927 YP_002734216.1 CDS BMEA_B0415 NC_012442.1 405020 406333 D hypothetical protein 405020..406333 Brucella melitensis ATCC 23457 7670928 YP_002734217.1 CDS BMEA_B0416 NC_012442.1 406296 406787 R dTDP-4-dehydrorhamnose 3,5-epimerase complement(406296..406787) Brucella melitensis ATCC 23457 7670929 YP_002734218.1 CDS BMEA_B0417 NC_012442.1 407140 408441 D C-methyltransferase 407140..408441 Brucella melitensis ATCC 23457 7670930 YP_002734219.1 CDS BMEA_B0418 NC_012442.1 408444 409253 D glucose-1-phosphate cytidylyltransferase 408444..409253 Brucella melitensis ATCC 23457 7670931 YP_002734220.1 CDS BMEA_B0419 NC_012442.1 409250 409906 D LmbE family protein 409250..409906 Brucella melitensis ATCC 23457 7670932 YP_002734221.1 CDS BMEA_B0420 NC_012442.1 409974 410105 D hypothetical protein 409974..410105 Brucella melitensis ATCC 23457 7670933 YP_002734222.1 CDS BMEA_B0421 NC_012442.1 410102 411382 R uracil-xanthine permease complement(410102..411382) Brucella melitensis ATCC 23457 7670934 YP_002734223.1 CDS BMEA_B0424 NC_012442.1 414527 415414 D HTH-type transcriptional regulator BudR 414527..415414 Brucella melitensis ATCC 23457 7670937 YP_002734224.1 CDS msrB NC_012442.1 415499 415939 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 415499..415939 Brucella melitensis ATCC 23457 7670938 YP_002734225.1 CDS BMEA_B0426 NC_012442.1 415924 417066 R acyl-CoA dehydrogenase complement(415924..417066) Brucella melitensis ATCC 23457 7670939 YP_002734226.1 CDS BMEA_B0427 NC_012442.1 417066 418256 R acetyl-CoA acetyltransferase complement(417066..418256) Brucella melitensis ATCC 23457 7670940 YP_002734227.1 CDS BMEA_B0428 NC_012442.1 418325 419092 R 3-hydroxyacyl-CoA dehydrogenase type-2 complement(418325..419092) Brucella melitensis ATCC 23457 7670941 YP_002734228.1 CDS BMEA_B0431 NC_012442.1 421932 422111 D hypothetical protein 421932..422111 Brucella melitensis ATCC 23457 7670944 YP_002734229.1 CDS BMEA_B0432 NC_012442.1 422108 423352 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 422108..423352 Brucella melitensis ATCC 23457 7670945 YP_002734230.1 CDS def NC_012442.1 423405 423899 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(423405..423899) Brucella melitensis ATCC 23457 7670946 YP_002734231.1 CDS BMEA_B0434 NC_012442.1 424645 425586 R hypothetical protein complement(424645..425586) Brucella melitensis ATCC 23457 7670947 YP_002734232.1 CDS BMEA_B0435 NC_012442.1 425899 426222 D regulatory protein ArsR 425899..426222 Brucella melitensis ATCC 23457 7670948 YP_002734233.1 CDS BMEA_B0436 NC_012442.1 426219 426629 D hypothetical protein 426219..426629 Brucella melitensis ATCC 23457 7670949 YP_002734234.1 CDS BMEA_B0437 NC_012442.1 426626 427063 D hypothetical protein 426626..427063 Brucella melitensis ATCC 23457 7670950 YP_002734235.1 CDS BMEA_B0438 NC_012442.1 427086 427793 R GntR family transcriptional regulator complement(427086..427793) Brucella melitensis ATCC 23457 7670951 YP_002734236.1 CDS BMEA_B0439 NC_012442.1 428039 429097 D hypothetical protein 428039..429097 Brucella melitensis ATCC 23457 7670952 YP_002734237.1 CDS BMEA_B0440 NC_012442.1 429640 430359 D TetR family transcriptional regulator 429640..430359 Brucella melitensis ATCC 23457 7670953 YP_002734238.1 CDS BMEA_B0441 NC_012442.1 430364 431308 D secretion protein HlyD family protein 430364..431308 Brucella melitensis ATCC 23457 7670954 YP_002734239.1 CDS BMEA_B0442 NC_012442.1 431220 432239 D ABC transporter 431220..432239 Brucella melitensis ATCC 23457 7670955 YP_002734240.1 CDS BMEA_B0443 NC_012442.1 432236 433375 D ABC transporter 432236..433375 Brucella melitensis ATCC 23457 7670956 YP_002734241.1 CDS BMEA_B0444 NC_012442.1 433413 433811 D cupin 2 conserved barrel domain-containing protein 433413..433811 Brucella melitensis ATCC 23457 7670957 YP_002734242.1 CDS BMEA_B0445 NC_012442.1 433818 434636 R binding-protein-dependent transport systems inner membrane component complement(433818..434636) Brucella melitensis ATCC 23457 7670958 YP_002734243.1 CDS BMEA_B0446 NC_012442.1 434629 435396 R ABC transporter complement(434629..435396) Brucella melitensis ATCC 23457 7670959 YP_002734244.1 CDS BMEA_B0447 NC_012442.1 435442 436464 R NMT1/THI5 like domain-containing protein complement(435442..436464) Brucella melitensis ATCC 23457 7670960 YP_002734245.1 CDS BMEA_B0448 NC_012442.1 436811 437299 D transcriptional regulator slyA 436811..437299 Brucella melitensis ATCC 23457 7670961 YP_002734246.1 CDS BMEA_B0450 NC_012442.1 438946 439995 D secretion protein HlyD family protein 438946..439995 Brucella melitensis ATCC 23457 7670963 YP_002734247.1 CDS BMEA_B0451 NC_012442.1 440067 441491 R two-component sensor histidine kinase complement(440067..441491) Brucella melitensis ATCC 23457 7670964 YP_002734248.1 CDS BMEA_B0452 NC_012442.1 441488 442204 R putative transcriptional regulator ycf27 complement(441488..442204) Brucella melitensis ATCC 23457 7670965 YP_002734249.1 CDS BMEA_B0454 NC_012442.1 442528 442893 D hypothetical protein 442528..442893 Brucella melitensis ATCC 23457 7670966 YP_002734250.1 CDS BMEA_B0455 NC_012442.1 442890 443123 D hypothetical protein 442890..443123 Brucella melitensis ATCC 23457 7670967 YP_002734251.1 CDS BMEA_B0456 NC_012442.1 443318 443668 D hypothetical protein 443318..443668 Brucella melitensis ATCC 23457 7670968 YP_002734252.1 CDS BMEA_B0457 NC_012442.1 443791 445065 R FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(443791..445065) Brucella melitensis ATCC 23457 7670969 YP_002734253.1 CDS BMEA_B0458 NC_012442.1 445148 445597 R transcriptional regulator hosA complement(445148..445597) Brucella melitensis ATCC 23457 7670970 YP_002734254.1 CDS BMEA_B0459 NC_012442.1 445879 446658 D glyoxalase/bleomycin resistance protein/dioxygenase 445879..446658 Brucella melitensis ATCC 23457 7670971 YP_002734255.1 CDS BMEA_B0460 NC_012442.1 446722 446892 R hypothetical protein complement(446722..446892) Brucella melitensis ATCC 23457 7670972 YP_002734256.1 CDS agcS NC_012442.1 446939 448372 R amino acid carrier protein complement(446939..448372) Brucella melitensis ATCC 23457 7670973 YP_002734257.1 CDS metA NC_012442.1 449366 450286 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(449366..450286) Brucella melitensis ATCC 23457 7670975 YP_002734258.1 CDS BMEA_B0464 NC_012442.1 450401 450901 D hypothetical protein 450401..450901 Brucella melitensis ATCC 23457 7670976 YP_002734259.1 CDS BMEA_B0465 NC_012442.1 451130 452110 R FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(451130..452110) Brucella melitensis ATCC 23457 7670977 YP_002734260.1 CDS bioA NC_012442.1 452107 453381 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(452107..453381) Brucella melitensis ATCC 23457 7670978 YP_002734261.1 CDS bioD NC_012442.1 453378 454016 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(453378..454016) Brucella melitensis ATCC 23457 7670979 YP_002734262.1 CDS BMEA_B0468 NC_012442.1 454013 455149 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(454013..455149) Brucella melitensis ATCC 23457 7670980 YP_002734263.1 CDS bioB NC_012442.1 455146 456186 R biotin synthase complement(455146..456186) Brucella melitensis ATCC 23457 7670981 YP_002734264.1 CDS BMEA_B0470 NC_012442.1 456425 456565 D hypothetical protein 456425..456565 Brucella melitensis ATCC 23457 7670982 YP_002734265.1 CDS BMEA_B0471 NC_012442.1 456543 456824 R hypothetical protein complement(456543..456824) Brucella melitensis ATCC 23457 7670983 YP_002734266.1 CDS mogA NC_012442.1 457087 457605 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 457087..457605 Brucella melitensis ATCC 23457 7670984 YP_002734267.1 CDS BMEA_B0473 NC_012442.1 457657 458256 R hypothetical protein complement(457657..458256) Brucella melitensis ATCC 23457 7670985 YP_002734268.1 CDS BMEA_B0475 NC_012442.1 460349 463267 D subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; putative monovalent cation/H+ antiporter subunit A 460349..463267 Brucella melitensis ATCC 23457 7670987 YP_002734269.1 CDS BMEA_B0476 NC_012442.1 463267 463605 D subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C 463267..463605 Brucella melitensis ATCC 23457 7670988 YP_002734270.1 CDS BMEA_B0477 NC_012442.1 463608 465236 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 463608..465236 Brucella melitensis ATCC 23457 7670989 YP_002734271.1 CDS BMEA_B0478 NC_012442.1 465233 465748 D subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit E 465233..465748 Brucella melitensis ATCC 23457 7670990 YP_002734272.1 CDS BMEA_B0479 NC_012442.1 465745 466026 D subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F 465745..466026 Brucella melitensis ATCC 23457 7670991 YP_002734273.1 CDS BMEA_B0480 NC_012442.1 466023 466385 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit G 466023..466385 Brucella melitensis ATCC 23457 7670992 YP_002734274.1 CDS BMEA_B0481 NC_012442.1 466810 467346 D hypothetical protein 466810..467346 Brucella melitensis ATCC 23457 7670993 YP_002734275.1 CDS cydD NC_012442.1 467454 469079 D cysteine ABC transporter permease/ATP-binding protein CydC 467454..469079 Brucella melitensis ATCC 23457 7670994 YP_002734276.1 CDS BMEA_B0483 NC_012442.1 469076 470746 D cysteine ABC transporter permease/ATP-binding protein CydC 469076..470746 Brucella melitensis ATCC 23457 7670995 YP_002734277.1 CDS BMEA_B0484 NC_012442.1 470889 472466 D cytochrome d ubiquinol oxidase subunit 1 470889..472466 Brucella melitensis ATCC 23457 7670996 YP_002734278.1 CDS cydB NC_012442.1 472472 473626 D cytochrome d ubiquinol oxidase subunit II 472472..473626 Brucella melitensis ATCC 23457 7670997 YP_002734279.1 CDS BMEA_B0486 NC_012442.1 473604 473798 D cyd operon protein YbgT 473604..473798 Brucella melitensis ATCC 23457 7670998 YP_002734280.1 CDS BMEA_B0487 NC_012442.1 473849 474622 R GntR family transcriptional regulator complement(473849..474622) Brucella melitensis ATCC 23457 7670999 YP_002734281.1 CDS BMEA_B0488 NC_012442.1 474619 475506 R BadF/BadG/BcrA/BcrD type ATPase complement(474619..475506) Brucella melitensis ATCC 23457 7671000 YP_002734282.1 CDS BMEA_B0489 NC_012442.1 475670 475858 D hypothetical protein 475670..475858 Brucella melitensis ATCC 23457 7671001 YP_002734283.1 CDS BMEA_B0492 NC_012442.1 477412 478431 D binding-protein-dependent transport systems inner membrane component 477412..478431 Brucella melitensis ATCC 23457 7671003 YP_002734284.1 CDS BMEA_B0493 NC_012442.1 478444 479283 D binding-protein-dependent transport systems inner membrane component 478444..479283 Brucella melitensis ATCC 23457 7671004 YP_002734285.1 CDS BMEA_B0494 NC_012442.1 479280 480350 D oxidoreductase domain-containing protein 479280..480350 Brucella melitensis ATCC 23457 7671005 YP_002734286.1 CDS BMEA_B0495 NC_012442.1 480380 481381 D ATP-binding transport protein SmoK 480380..481381 Brucella melitensis ATCC 23457 7671006 YP_002734287.1 CDS BMEA_B0496 NC_012442.1 481434 481685 D hypothetical protein 481434..481685 Brucella melitensis ATCC 23457 7671007 YP_002734288.1 CDS BMEA_B0497 NC_012442.1 481982 483214 D 2-oxoisovalerate dehydrogenase subunit alpha 481982..483214 Brucella melitensis ATCC 23457 7671008 YP_002734289.1 CDS BMEA_B0498 NC_012442.1 483318 484331 D 2-oxoisovalerate dehydrogenase subunit beta 483318..484331 Brucella melitensis ATCC 23457 7671009 YP_002734290.1 CDS BMEA_B0499 NC_012442.1 484332 485627 D branched-chain alpha-keto acid dehydrogenase subunit E2 484332..485627 Brucella melitensis ATCC 23457 7671010 YP_002734291.1 CDS lpdA NC_012442.1 485725 487026 D E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 485725..487026 Brucella melitensis ATCC 23457 7671011 YP_002734292.1 CDS BMEA_B0501 NC_012442.1 487015 487776 R Surfeit locus 1 family protein complement(487015..487776) Brucella melitensis ATCC 23457 7671012 YP_002734293.1 CDS BMEA_B0503 NC_012442.1 488035 488289 D hypothetical protein 488035..488289 Brucella melitensis ATCC 23457 7671013 YP_002734294.1 CDS BMEA_B0504 NC_012442.1 488470 490935 R DNA translocase ftsK complement(488470..490935) Brucella melitensis ATCC 23457 7671014 YP_002734295.1 CDS BMEA_B0505 NC_012442.1 491230 492252 R peptidase S58 DmpA complement(491230..492252) Brucella melitensis ATCC 23457 7671015 YP_002734296.1 CDS BMEA_B0506 NC_012442.1 492499 493809 D major facilitator superfamily protein 492499..493809 Brucella melitensis ATCC 23457 7671016 YP_002734297.1 CDS BMEA_B0507 NC_012442.1 493968 494606 R alkylated DNA repair protein AlkB complement(493968..494606) Brucella melitensis ATCC 23457 7671017 YP_002734298.1 CDS BMEA_B0508 NC_012442.1 494688 496298 R ABC transporter complement(494688..496298) Brucella melitensis ATCC 23457 7671018 YP_002734299.1 CDS BMEA_B0509 NC_012442.1 496300 497433 R binding-protein-dependent transport systems inner membrane component complement(496300..497433) Brucella melitensis ATCC 23457 7671019 YP_002734300.1 CDS BMEA_B0510 NC_012442.1 497426 498349 R hypothetical protein complement(497426..498349) Brucella melitensis ATCC 23457 7671020 YP_002734301.1 CDS BMEA_B0511 NC_012442.1 498564 500141 R oligopeptide-binding protein oppA complement(498564..500141) Brucella melitensis ATCC 23457 7671021 YP_002734302.1 CDS BMEA_B0512 NC_012442.1 500252 501829 R oligopeptide-binding protein oppA complement(500252..501829) Brucella melitensis ATCC 23457 7671022 YP_002734303.1 CDS BMEA_B0513 NC_012442.1 501923 502093 R hypothetical protein complement(501923..502093) Brucella melitensis ATCC 23457 7671023 YP_002734304.1 CDS BMEA_B0514 NC_012442.1 502256 502603 R hypothetical protein complement(502256..502603) Brucella melitensis ATCC 23457 7671024 YP_002734305.1 CDS BMEA_B0515 NC_012442.1 502845 503441 D NAD-dependent epimerase/dehydratase 502845..503441 Brucella melitensis ATCC 23457 7671025 YP_002734306.1 CDS galE NC_012442.1 503441 504427 D UDP-glucose 4-epimerase 503441..504427 Brucella melitensis ATCC 23457 7671026 YP_002734307.1 CDS BMEA_B0518 NC_012442.1 506275 507699 D nucleotide sugar dehydrogenase 506275..507699 Brucella melitensis ATCC 23457 7671028 YP_002734308.1 CDS BMEA_B0519 NC_012442.1 507689 508234 D hypothetical protein 507689..508234 Brucella melitensis ATCC 23457 7671029 YP_002734309.1 CDS BMEA_B0520 NC_012442.1 508284 509228 D mannan endo-1,4-beta-mannosidase A and B 508284..509228 Brucella melitensis ATCC 23457 7671030 YP_002734310.1 CDS BMEA_B0521 NC_012442.1 509348 509842 D hypothetical protein 509348..509842 Brucella melitensis ATCC 23457 7671031 YP_002734311.1 CDS BMEA_B0522 NC_012442.1 509959 510285 R hypothetical protein complement(509959..510285) Brucella melitensis ATCC 23457 7671032 YP_002734312.1 CDS BMEA_B0524 NC_012442.1 512023 512667 R hypothetical protein complement(512023..512667) Brucella melitensis ATCC 23457 7671034 YP_002734313.1 CDS BMEA_B0525 NC_012442.1 512642 514666 R glycoprotein X complement(512642..514666) Brucella melitensis ATCC 23457 7671035 YP_002734314.1 CDS BMEA_B0527 NC_012442.1 515242 515847 R yecA family protein complement(515242..515847) Brucella melitensis ATCC 23457 7671036 YP_002734315.1 CDS BMEA_B0528 NC_012442.1 515844 517415 R transposase IS66 complement(515844..517415) Brucella melitensis ATCC 23457 7671037 YP_002734316.1 CDS BMEA_B0529 NC_012442.1 517465 517851 R IS66 family element complement(517465..517851) Brucella melitensis ATCC 23457 7671038 YP_002734317.1 CDS BMEA_B0530 NC_012442.1 517815 518282 R transposase IS3/IS911 family protein complement(517815..518282) Brucella melitensis ATCC 23457 7671039 YP_002734318.1 CDS BMEA_B0531 NC_012442.1 518363 518725 R ISBm1, transposase orfA complement(518363..518725) Brucella melitensis ATCC 23457 7671040 YP_002734319.1 CDS BMEA_B0532 NC_012442.1 519491 519898 D hypothetical protein 519491..519898 Brucella melitensis ATCC 23457 7671041 YP_002734320.1 CDS BMEA_B0534 NC_012442.1 520371 520829 D YbaK/prolyl-tRNA synthetase associated protein 520371..520829 Brucella melitensis ATCC 23457 7671043 YP_002734321.1 CDS rirA NC_012442.1 521075 521536 D rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 521075..521536 Brucella melitensis ATCC 23457 7671044 YP_002734322.1 CDS BMEA_B0536 NC_012442.1 521653 521967 D antibiotic biosynthesis monooxygenase 521653..521967 Brucella melitensis ATCC 23457 7671045 YP_002734323.1 CDS BMEA_B0537 NC_012442.1 522423 522734 D hypothetical protein 522423..522734 Brucella melitensis ATCC 23457 7671046 YP_002734324.1 CDS bfr NC_012442.1 522700 523185 D bacterioferritin 522700..523185 Brucella melitensis ATCC 23457 7671047 YP_002734325.1 CDS rimO NC_012442.1 523349 524662 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 523349..524662 Brucella melitensis ATCC 23457 7671048 YP_002734326.1 CDS BMEA_B0540 NC_012442.1 524802 525869 R basic membrane lipoprotein complement(524802..525869) Brucella melitensis ATCC 23457 7671049 YP_002734327.1 CDS BMEA_B0541 NC_012442.1 525952 526872 R inner-membrane translocator complement(525952..526872) Brucella melitensis ATCC 23457 7671050 YP_002734328.1 CDS BMEA_B0543 NC_012442.1 527958 529520 R ABC transporter complement(527958..529520) Brucella melitensis ATCC 23457 7671052 YP_002734329.1 CDS BMEA_B0545 NC_012442.1 530595 531395 R phosphatidylcholine synthase complement(530595..531395) Brucella melitensis ATCC 23457 7671054 YP_002734330.1 CDS BMEA_B0546 NC_012442.1 531611 532969 D 2-octaprenyl-6-methoxyphenyl hydroxylase 531611..532969 Brucella melitensis ATCC 23457 7671055 YP_002734331.1 CDS BMEA_B0547 NC_012442.1 533042 533380 D hemimethylated DNA binding domain-containing protein 533042..533380 Brucella melitensis ATCC 23457 7671056 YP_002734332.1 CDS BMEA_B0548 NC_012442.1 533513 534130 R hypothetical protein complement(533513..534130) Brucella melitensis ATCC 23457 7671057 YP_002734333.1 CDS BMEA_B0549 NC_012442.1 534475 536322 D family 5 extracellular solute-binding protein 534475..536322 Brucella melitensis ATCC 23457 7671058 YP_002734334.1 CDS BMEA_B0550 NC_012442.1 536394 536504 D hypothetical protein 536394..536504 Brucella melitensis ATCC 23457 7671059 YP_002734335.1 CDS BMEA_B0551 NC_012442.1 536501 537175 D DSBA oxidoreductase 536501..537175 Brucella melitensis ATCC 23457 7671060 YP_002734336.1 CDS BMEA_B0552 NC_012442.1 537353 537751 R metallothiol transferase FosB complement(537353..537751) Brucella melitensis ATCC 23457 7671061 YP_002734337.1 CDS mfd NC_012442.1 537844 541356 R transcription-repair coupling factor complement(537844..541356) Brucella melitensis ATCC 23457 7671062 YP_002734338.1 CDS BMEA_B0554 NC_012442.1 541367 541654 R hypothetical protein complement(541367..541654) Brucella melitensis ATCC 23457 7671063 YP_002734339.1 CDS recG NC_012442.1 541793 543913 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 541793..543913 Brucella melitensis ATCC 23457 7671064 YP_002734340.1 CDS glmS NC_012442.1 544068 545891 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(544068..545891) Brucella melitensis ATCC 23457 7671065 YP_002734341.1 CDS glmU NC_012442.1 545995 547359 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(545995..547359) Brucella melitensis ATCC 23457 7671066 YP_002734342.1 CDS BMEA_B0558 NC_012442.1 547441 548202 R cytochrome c biogenesis protein complement(547441..548202) Brucella melitensis ATCC 23457 7671067 YP_002734343.1 CDS BMEA_B0559 NC_012442.1 548351 550993 D putative lysylphosphatidylglycerol synthetase 548351..550993 Brucella melitensis ATCC 23457 7671068 YP_002734344.1 CDS BMEA_B0560 NC_012442.1 551242 552402 D virulence factor family protein 551242..552402 Brucella melitensis ATCC 23457 7671069 YP_002734345.1 CDS BMEA_B0562 NC_012442.1 552906 553406 R BA14K family protein complement(552906..553406) Brucella melitensis ATCC 23457 7671071 YP_002734346.1 CDS BMEA_B0563 NC_012442.1 553724 555115 D PAS domain S-box-containing protein 553724..555115 Brucella melitensis ATCC 23457 7671072 YP_002734347.1 CDS lipB NC_012442.1 555243 556037 D lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 555243..556037 Brucella melitensis ATCC 23457 7671073 YP_002734348.1 CDS BMEA_B0565 NC_012442.1 556041 556970 R hypothetical protein complement(556041..556970) Brucella melitensis ATCC 23457 7671074 YP_002734349.1 CDS parE NC_012442.1 557275 559374 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 557275..559374 Brucella melitensis ATCC 23457 7671075 YP_002734350.1 CDS BMEA_B0567 NC_012442.1 559380 559553 R hypothetical protein complement(559380..559553) Brucella melitensis ATCC 23457 7671076 YP_002734351.1 CDS BMEA_B0568 NC_012442.1 559547 559771 R hypothetical protein complement(559547..559771) Brucella melitensis ATCC 23457 7671077 YP_002734352.1 CDS gatA NC_012442.1 559796 561277 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(559796..561277) Brucella melitensis ATCC 23457 7671078 YP_002734353.1 CDS gatC NC_012442.1 561336 561623 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(561336..561623) Brucella melitensis ATCC 23457 7671079 YP_002734354.1 CDS BMEA_B0571 NC_012442.1 561718 562431 R catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase complement(561718..562431) Brucella melitensis ATCC 23457 7671080 YP_002734355.1 CDS BMEA_B0572 NC_012442.1 562531 563019 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 562531..563019 Brucella melitensis ATCC 23457 7671081 YP_002734356.1 CDS BMEA_B0573 NC_012442.1 563004 564659 R acyl-CoA dehydrogenase domain-containing protein complement(563004..564659) Brucella melitensis ATCC 23457 7671082 YP_002734357.1 CDS pyrB NC_012442.1 564816 565784 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 564816..565784 Brucella melitensis ATCC 23457 7671083 YP_002734358.1 CDS pyrC NC_012442.1 565781 567067 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 565781..567067 Brucella melitensis ATCC 23457 7671084 YP_002734359.1 CDS BMEA_B0576 NC_012442.1 567142 567747 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 567142..567747 Brucella melitensis ATCC 23457 7671085 YP_002734360.1 CDS dprA NC_012442.1 567744 568925 D DNA protecting protein DprA 567744..568925 Brucella melitensis ATCC 23457 7671086 YP_002734361.1 CDS BMEA_B0578 NC_012442.1 568935 569102 R hypothetical protein complement(568935..569102) Brucella melitensis ATCC 23457 7671087 YP_002734362.1 CDS topA NC_012442.1 569358 571991 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 569358..571991 Brucella melitensis ATCC 23457 7671088 YP_002734363.1 CDS rnr NC_012442.1 571995 574346 D ribonuclease R 571995..574346 Brucella melitensis ATCC 23457 7671089 YP_002734364.1 CDS BMEA_B0581 NC_012442.1 574346 574807 D hypothetical protein 574346..574807 Brucella melitensis ATCC 23457 7671090 YP_002734365.1 CDS BMEA_B0582 NC_012442.1 574816 575547 D NUDIX hydrolase 574816..575547 Brucella melitensis ATCC 23457 7671091 YP_002734366.1 CDS BMEA_B0583 NC_012442.1 575622 576764 D major facilitator superfamily protein 575622..576764 Brucella melitensis ATCC 23457 7671092 YP_002734367.1 CDS rpmG NC_012442.1 576923 577090 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 576923..577090 Brucella melitensis ATCC 23457 7671093 YP_002734368.1 CDS pleD NC_012442.1 577197 578582 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(577197..578582) Brucella melitensis ATCC 23457 7671094 YP_002734369.1 CDS BMEA_B0586 NC_012442.1 578579 578710 R hypothetical protein complement(578579..578710) Brucella melitensis ATCC 23457 7671095 YP_002734370.1 CDS BMEA_B0587 NC_012442.1 578703 579074 R hypothetical protein complement(578703..579074) Brucella melitensis ATCC 23457 7671096 YP_002734371.1 CDS BMEA_B0588 NC_012442.1 579177 579542 D hypothetical protein 579177..579542 Brucella melitensis ATCC 23457 7671097 YP_002734372.1 CDS BMEA_B0590 NC_012442.1 580557 581894 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 580557..581894 Brucella melitensis ATCC 23457 7671099 YP_002734373.1 CDS BMEA_B0591 NC_012442.1 582064 584253 D hypothetical protein 582064..584253 Brucella melitensis ATCC 23457 7671100 YP_002734374.1 CDS BMEA_B0592 NC_012442.1 584233 584355 R hypothetical protein complement(584233..584355) Brucella melitensis ATCC 23457 7671101 YP_002734375.1 CDS BMEA_B0594 NC_012442.1 584782 585495 R GGDEF domain-containing protein complement(584782..585495) Brucella melitensis ATCC 23457 7671103 YP_002734376.1 CDS BMEA_B0595 NC_012442.1 586403 586780 R Pyrimidine dimer DNA glycosylase complement(586403..586780) Brucella melitensis ATCC 23457 7671104 YP_002734377.1 CDS BMEA_B0596 NC_012442.1 586921 587226 D hypothetical protein 586921..587226 Brucella melitensis ATCC 23457 7671105 YP_002734378.1 CDS BMEA_B0597 NC_012442.1 587371 587559 D hypothetical protein 587371..587559 Brucella melitensis ATCC 23457 7671106 YP_002734379.1 CDS BMEA_B0598 NC_012442.1 587610 587903 D hypothetical protein 587610..587903 Brucella melitensis ATCC 23457 7671107 YP_002734380.1 CDS BMEA_B0599 NC_012442.1 587997 588671 D exonuclease, DNA polymerase III, epsilon subunit family protein 587997..588671 Brucella melitensis ATCC 23457 7671108 YP_002734381.1 CDS BMEA_B0601 NC_012442.1 589047 589328 D hypothetical protein 589047..589328 Brucella melitensis ATCC 23457 7671110 YP_002734382.1 CDS BMEA_B0602 NC_012442.1 589429 590388 R putative transcriptional regulator lumQ complement(589429..590388) Brucella melitensis ATCC 23457 7671111 YP_002734383.1 CDS BMEA_B0603 NC_012442.1 590556 590717 R hypothetical protein complement(590556..590717) Brucella melitensis ATCC 23457 7671112 YP_002734384.1 CDS BMEA_B0604 NC_012442.1 590743 591993 R FAD dependent oxidoreductase complement(590743..591993) Brucella melitensis ATCC 23457 7671113 YP_002734385.1 CDS BMEA_B0606 NC_012442.1 593033 594136 R hypothetical protein complement(593033..594136) Brucella melitensis ATCC 23457 7671115 YP_002734386.1 CDS BMEA_B0607 NC_012442.1 594239 594688 D hypothetical protein 594239..594688 Brucella melitensis ATCC 23457 7671116 YP_002734387.1 CDS BMEA_B0608 NC_012442.1 594866 596695 D amidohydrolase 3 594866..596695 Brucella melitensis ATCC 23457 7671117 YP_002734388.1 CDS pcaF NC_012442.1 596806 598008 R catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase complement(596806..598008) Brucella melitensis ATCC 23457 7671118 YP_002734389.1 CDS BMEA_B0610 NC_012442.1 598017 598706 R 3-oxoacid CoA-transferase, B subunit complement(598017..598706) Brucella melitensis ATCC 23457 7671119 YP_002734390.1 CDS BMEA_B0611 NC_012442.1 598703 599410 R 3-oxoacid CoA-transferase, A subunit complement(598703..599410) Brucella melitensis ATCC 23457 7671120 YP_002734391.1 CDS BMEA_B0612 NC_012442.1 599594 600364 D beta-ketoadipate pathway transcriptional regulator 599594..600364 Brucella melitensis ATCC 23457 7671121 YP_002734392.1 CDS BMEA_B0613 NC_012442.1 600371 601288 R helix-turn-helix- domain containing protein complement(600371..601288) Brucella melitensis ATCC 23457 7671122 YP_002734393.1 CDS pobA NC_012442.1 601401 602570 D catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 601401..602570 Brucella melitensis ATCC 23457 7671123 YP_002734394.1 CDS pcaQ NC_012442.1 602980 603888 R pca operon transcription factor PcaQ complement(602980..603888) Brucella melitensis ATCC 23457 7671124 YP_002734395.1 CDS pcaD NC_012442.1 603982 604785 D 3-oxoadipate enol-lactonase 603982..604785 Brucella melitensis ATCC 23457 7671125 YP_002734396.1 CDS pcaC NC_012442.1 604789 605205 D 4-carboxymuconolactone decarboxylase 604789..605205 Brucella melitensis ATCC 23457 7671126 YP_002734397.1 CDS pcaG NC_012442.1 605944 606561 D protocatechuate 3,4-dioxygenase subunit alpha 605944..606561 Brucella melitensis ATCC 23457 7671128 YP_002734398.1 CDS pcaB NC_012442.1 606565 607629 D Catalyzes the cycloisomerization of cis,cis-muconate; 3-carboxy-cis,cis-muconate cycloisomerase 606565..607629 Brucella melitensis ATCC 23457 7671129 YP_002734399.1 CDS BMEA_B0621 NC_012442.1 607765 608937 D amino acid ABC transporter substrate-binding portion 607765..608937 Brucella melitensis ATCC 23457 7671130 YP_002734400.1 CDS BMEA_B0622 NC_012442.1 609109 609978 D hypothetical protein 609109..609978 Brucella melitensis ATCC 23457 7671131 YP_002734401.1 CDS BMEA_B0624 NC_012442.1 610957 611706 D ABC transporter 610957..611706 Brucella melitensis ATCC 23457 7671133 YP_002734402.1 CDS BMEA_B0625 NC_012442.1 611703 612419 D ABC transporter 611703..612419 Brucella melitensis ATCC 23457 7671134 YP_002734403.1 CDS ade NC_012442.1 612420 614261 R adenine deaminase complement(612420..614261) Brucella melitensis ATCC 23457 7671135 YP_002734404.1 CDS BMEA_B0627 NC_012442.1 614324 615364 D dipeptidase 614324..615364 Brucella melitensis ATCC 23457 7671136 YP_002734405.1 CDS BMEA_B0628 NC_012442.1 615697 616998 D sn-glycerol-3-phosphate-binding periplasmic protein UgpB 615697..616998 Brucella melitensis ATCC 23457 7671137 YP_002734406.1 CDS BMEA_B0629 NC_012442.1 617071 617943 D sn-glycerol-3-phosphate transport system permease UgpA 617071..617943 Brucella melitensis ATCC 23457 7671138 YP_002734407.1 CDS BMEA_B0630 NC_012442.1 617955 618803 D sn-glycerol-3-phosphate transport system permease UgpE 617955..618803 Brucella melitensis ATCC 23457 7671139 YP_002734408.1 CDS ugpC NC_012442.1 618803 619858 D part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 618803..619858 Brucella melitensis ATCC 23457 7671140 YP_002734409.1 CDS BMEA_B0633 NC_012442.1 621970 622569 R CMP/dCMP deaminase zinc-binding complement(621970..622569) Brucella melitensis ATCC 23457 7671142 YP_002734410.1 CDS BMEA_B0634 NC_012442.1 622630 623922 R Xanthine/uracil/vitamin C permease complement(622630..623922) Brucella melitensis ATCC 23457 7671143 YP_002734411.1 CDS BMEA_B0635 NC_012442.1 624191 624355 R hypothetical protein complement(624191..624355) Brucella melitensis ATCC 23457 7671144 YP_002734412.1 CDS BMEA_B0636 NC_012442.1 624360 624848 R hypothetical protein complement(624360..624848) Brucella melitensis ATCC 23457 7671145 YP_002734413.1 CDS BMEA_B0637 NC_012442.1 625031 625195 D hypothetical protein 625031..625195 Brucella melitensis ATCC 23457 7671146 YP_002734414.1 CDS BMEA_B0638 NC_012442.1 625199 625336 R hypothetical protein complement(625199..625336) Brucella melitensis ATCC 23457 7671147 YP_002734415.1 CDS BMEA_B0639 NC_012442.1 625595 626512 D hypothetical protein 625595..626512 Brucella melitensis ATCC 23457 7671148 YP_002734416.1 CDS BMEA_B0640 NC_012442.1 626594 627484 D aminotransferase 626594..627484 Brucella melitensis ATCC 23457 7671149 YP_002734417.1 CDS BMEA_B0641 NC_012442.1 627469 627660 D hypothetical protein 627469..627660 Brucella melitensis ATCC 23457 7671150 YP_002734418.1 CDS BMEA_B0642 NC_012442.1 627657 628418 D hypothetical protein 627657..628418 Brucella melitensis ATCC 23457 7671151 YP_002734419.1 CDS BMEA_B0644 NC_012442.1 630239 630724 R hypothetical protein complement(630239..630724) Brucella melitensis ATCC 23457 7671153 YP_002734420.1 CDS BMEA_B0645 NC_012442.1 630275 630679 D hypothetical protein 630275..630679 Brucella melitensis ATCC 23457 7671154 YP_002734421.1 CDS BMEA_B0646 NC_012442.1 630892 632250 D aldehyde dehydrogenase family protein 630892..632250 Brucella melitensis ATCC 23457 7671155 YP_002734422.1 CDS BMEA_B0647 NC_012442.1 632728 633675 D periplasmic binding protein 632728..633675 Brucella melitensis ATCC 23457 7671156 YP_002734423.1 CDS BMEA_B0648 NC_012442.1 633732 634694 D transport system permease 633732..634694 Brucella melitensis ATCC 23457 7671157 YP_002734424.1 CDS BMEA_B0649 NC_012442.1 634687 635640 D transport system permease 634687..635640 Brucella melitensis ATCC 23457 7671158 YP_002734425.1 CDS BMEA_B0650 NC_012442.1 635637 636395 D ABC transporter 635637..636395 Brucella melitensis ATCC 23457 7671159 YP_002734426.1 CDS BMEA_B0651 NC_012442.1 636448 637047 R transcriptional regulator complement(636448..637047) Brucella melitensis ATCC 23457 7671160 YP_002734427.1 CDS BMEA_B0652 NC_012442.1 637185 640796 D 5-oxoprolinase 637185..640796 Brucella melitensis ATCC 23457 7671161 YP_002734428.1 CDS BMEA_B0653 NC_012442.1 641082 641855 D family 3 extracellular solute-binding protein 641082..641855 Brucella melitensis ATCC 23457 7671162 YP_002734429.1 CDS BMEA_B0654 NC_012442.1 642035 642715 D amino acid ABC transporter permease 642035..642715 Brucella melitensis ATCC 23457 7671163 YP_002734430.1 CDS BMEA_B0655 NC_012442.1 642712 643473 D ABC transporter 642712..643473 Brucella melitensis ATCC 23457 7671164 YP_002734431.1 CDS BMEA_B0656 NC_012442.1 643625 645211 D Ppx/GppA phosphatase 643625..645211 Brucella melitensis ATCC 23457 7671165 YP_002734432.1 CDS BMEA_B0657 NC_012442.1 645213 645935 D Ribosomal RNA large subunit methyltransferase J 645213..645935 Brucella melitensis ATCC 23457 7671166 YP_002734433.1 CDS BMEA_B0658 NC_012442.1 646134 647543 R drug resistance transporter, EmrB/QacA subfamily protein complement(646134..647543) Brucella melitensis ATCC 23457 7671167 YP_002734434.1 CDS BMEA_B0659 NC_012442.1 647587 647871 R hypothetical protein complement(647587..647871) Brucella melitensis ATCC 23457 7671168 YP_002734435.1 CDS BMEA_B0660 NC_012442.1 648105 649220 R ABC transporter complement(648105..649220) Brucella melitensis ATCC 23457 7671169 YP_002734436.1 CDS BMEA_B0661 NC_012442.1 649239 650120 R hypothetical protein complement(649239..650120) Brucella melitensis ATCC 23457 7671170 YP_002734437.1 CDS BMEA_B0662 NC_012442.1 650117 651166 R putative starch degradation products transport system permease amyD complement(650117..651166) Brucella melitensis ATCC 23457 7671171 YP_002734438.1 CDS BMEA_B0663 NC_012442.1 651274 652539 R putative sugar-binding periplasmic protein complement(651274..652539) Brucella melitensis ATCC 23457 7671172 YP_002734439.1 CDS BMEA_B0664 NC_012442.1 653034 653282 R hypothetical protein complement(653034..653282) Brucella melitensis ATCC 23457 7671173 YP_002734440.1 CDS BMEA_B0667 NC_012442.1 653426 653902 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; riboflavin synthase subunit beta 653426..653902 Brucella melitensis ATCC 23457 7671174 YP_002734441.1 CDS fdhD NC_012442.1 653903 654712 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(653903..654712) Brucella melitensis ATCC 23457 7671175 YP_002734442.1 CDS BMEA_B0669 NC_012442.1 654822 655166 D hypothetical protein 654822..655166 Brucella melitensis ATCC 23457 7671176 YP_002734443.1 CDS BMEA_B0671 NC_012442.1 655236 655637 R hypothetical protein complement(655236..655637) Brucella melitensis ATCC 23457 7671177 YP_002734444.1 CDS BMEA_B0672 NC_012442.1 655815 657584 R binding-protein-dependent transport systems inner membrane component complement(655815..657584) Brucella melitensis ATCC 23457 7671178 YP_002734445.1 CDS BMEA_B0673 NC_012442.1 657605 658621 R family 1 extracellular solute-binding protein complement(657605..658621) Brucella melitensis ATCC 23457 7671179 YP_002734446.1 CDS BMEA_B0674 NC_012442.1 658747 659850 R ABC transporter complement(658747..659850) Brucella melitensis ATCC 23457 7671180 YP_002734447.1 CDS BMEA_B0675 NC_012442.1 659901 660071 D hypothetical protein 659901..660071 Brucella melitensis ATCC 23457 7671181 YP_002734448.1 CDS BMEA_B0677 NC_012442.1 661671 662192 R Superoxide dismutase, copper/zinc binding complement(661671..662192) Brucella melitensis ATCC 23457 7671183 YP_002734449.1 CDS BMEA_B0678 NC_012442.1 662465 664069 R laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase complement(662465..664069) Brucella melitensis ATCC 23457 7671184 YP_002734450.1 CDS BMEA_B0679 NC_012442.1 664129 664524 R hypothetical protein complement(664129..664524) Brucella melitensis ATCC 23457 7671185 YP_002734451.1 CDS BMEA_B0680 NC_012442.1 664777 666057 D major facilitator superfamily protein 664777..666057 Brucella melitensis ATCC 23457 7671186 YP_002734452.1 CDS ahpD NC_012442.1 666032 666661 R alkylhydroperoxidase complement(666032..666661) Brucella melitensis ATCC 23457 7671187 YP_002734453.1 CDS BMEA_B0682 NC_012442.1 666741 667295 R Thioredoxin peroxidase 2 complement(666741..667295) Brucella melitensis ATCC 23457 7671188 YP_002734454.1 CDS BMEA_B0684 NC_012442.1 667421 668326 D LysR family transcriptional regulator 667421..668326 Brucella melitensis ATCC 23457 7671189 YP_002734455.1 CDS BMEA_B0685 NC_012442.1 668356 669423 R hypothetical protein complement(668356..669423) Brucella melitensis ATCC 23457 7671190 YP_002734456.1 CDS BMEA_B0686 NC_012442.1 669521 670525 R Rhizopine catabolism protein mocA complement(669521..670525) Brucella melitensis ATCC 23457 7671191 YP_002734457.1 CDS BMEA_B0687 NC_012442.1 670699 671529 D RpiR family transcriptional regulator 670699..671529 Brucella melitensis ATCC 23457 7671192 YP_002734458.1 CDS BMEA_B0688 NC_012442.1 671621 673525 D Fructokinase-1 671621..673525 Brucella melitensis ATCC 23457 7671193 YP_002734459.1 CDS BMEA_B0689 NC_012442.1 673558 675381 D thiamine pyrophosphate protein 673558..675381 Brucella melitensis ATCC 23457 7671194 YP_002734460.1 CDS BMEA_B0690 NC_012442.1 675385 676287 D Rhizopine catabolism protein mocC 675385..676287 Brucella melitensis ATCC 23457 7671195 YP_002734461.1 CDS BMEA_B0691 NC_012442.1 676291 677100 D Myo-inositol catabolism IolB domain-containing protein 676291..677100 Brucella melitensis ATCC 23457 7671196 YP_002734462.1 CDS BMEA_B0692 NC_012442.1 677132 677932 R inositol monophosphatase family protein complement(677132..677932) Brucella melitensis ATCC 23457 7671197 YP_002734463.1 CDS BMEA_B0693 NC_012442.1 677953 679014 R ABC transporter complement(677953..679014) Brucella melitensis ATCC 23457 7671198 YP_002734464.1 CDS BMEA_B0694 NC_012442.1 679011 681236 R ferric transport system permease FbpB complement(679011..681236) Brucella melitensis ATCC 23457 7671199 YP_002734465.1 CDS BMEA_B0695 NC_012442.1 681371 682396 R iron ABC transporter substrate-binding protein complement(681371..682396) Brucella melitensis ATCC 23457 7671200 YP_002734466.1 CDS BMEA_B0697 NC_012442.1 682626 686309 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(682626..686309) Brucella melitensis ATCC 23457 7671201 YP_002734467.1 CDS BMEA_B0698 NC_012442.1 686472 686966 D proline dehydrogenase transcriptional activator 686472..686966 Brucella melitensis ATCC 23457 7671202 YP_002734468.1 CDS gcvP NC_012442.1 687996 690794 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(687996..690794) Brucella melitensis ATCC 23457 7671204 YP_002734469.1 CDS gcvH NC_012442.1 690799 691167 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(690799..691167) Brucella melitensis ATCC 23457 7671205 YP_002734470.1 CDS gcvT NC_012442.1 691173 692276 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(691173..692276) Brucella melitensis ATCC 23457 7671206 YP_002734471.1 CDS BMEA_B0706 NC_012442.1 692918 693076 D hypothetical protein 692918..693076 Brucella melitensis ATCC 23457 7671207 YP_002734472.1 CDS BMEA_B0708 NC_012442.1 694594 695436 R RpiR family transcriptional regulator complement(694594..695436) Brucella melitensis ATCC 23457 7671209 YP_002734473.1 CDS BMEA_B0709 NC_012442.1 695565 696362 D N-formylglutamate amidohydrolase 695565..696362 Brucella melitensis ATCC 23457 7671210 YP_002734474.1 CDS BMEA_B0710 NC_012442.1 696426 697793 D glutamate--ammonia ligase 696426..697793 Brucella melitensis ATCC 23457 7671211 YP_002734475.1 CDS BMEA_B0711 NC_012442.1 697787 697903 R hypothetical protein complement(697787..697903) Brucella melitensis ATCC 23457 7671212 YP_002734476.1 CDS BMEA_B0712 NC_012442.1 697894 699063 D 1,3-propanediol dehydrogenase 697894..699063 Brucella melitensis ATCC 23457 7671213 YP_002734477.1 CDS BMEA_B0713 NC_012442.1 699245 699688 D BA14K family protein 699245..699688 Brucella melitensis ATCC 23457 7671214 YP_002734478.1 CDS BMEA_B0714 NC_012442.1 699818 700015 D hypothetical protein 699818..700015 Brucella melitensis ATCC 23457 7671215 YP_002734479.1 CDS BMEA_B0715 NC_012442.1 700097 700996 D hypothetical protein 700097..700996 Brucella melitensis ATCC 23457 7671216 YP_002734480.1 CDS BMEA_B0716 NC_012442.1 701042 701908 R glycine/betaine ABC transporter substrate-binding protein complement(701042..701908) Brucella melitensis ATCC 23457 7671217 YP_002734481.1 CDS BMEA_B0717 NC_012442.1 701962 702867 R binding-protein-dependent transport systems inner membrane component complement(701962..702867) Brucella melitensis ATCC 23457 7671218 YP_002734482.1 CDS proV NC_012442.1 702930 704096 R glycine betaine/L-proline transporter ATP binding subunit complement(702930..704096) Brucella melitensis ATCC 23457 7671219 YP_002734483.1 CDS BMEA_B0719 NC_012442.1 704309 704494 R hypothetical protein complement(704309..704494) Brucella melitensis ATCC 23457 7671220 YP_002734484.1 CDS BMEA_B0720 NC_012442.1 704657 705130 R hypothetical protein complement(704657..705130) Brucella melitensis ATCC 23457 7671221 YP_002734485.1 CDS BMEA_B0721 NC_012442.1 705144 706211 R alanine racemase domain-containing protein complement(705144..706211) Brucella melitensis ATCC 23457 7671222 YP_002734486.1 CDS BMEA_B0722 NC_012442.1 706216 707097 R RpiR family transcriptional regulator complement(706216..707097) Brucella melitensis ATCC 23457 7671223 YP_002734487.1 CDS BMEA_B0723 NC_012442.1 707105 708157 R ATP-binding transport protein SmoK complement(707105..708157) Brucella melitensis ATCC 23457 7671224 YP_002734488.1 CDS BMEA_B0724 NC_012442.1 708162 708935 R Peroxisomal 2,4-dienoyl-CoA reductase complement(708162..708935) Brucella melitensis ATCC 23457 7671225 YP_002734489.1 CDS BMEA_B0725 NC_012442.1 709115 710350 D family 1 extracellular solute-binding protein 709115..710350 Brucella melitensis ATCC 23457 7671226 YP_002734490.1 CDS BMEA_B0726 NC_012442.1 710422 711291 D binding-protein-dependent transport systems inner membrane component 710422..711291 Brucella melitensis ATCC 23457 7671227 YP_002734491.1 CDS BMEA_B0727 NC_012442.1 711288 712115 D binding-protein-dependent transport systems inner membrane component 711288..712115 Brucella melitensis ATCC 23457 7671228 YP_002734492.1 CDS BMEA_B0728 NC_012442.1 712128 712499 D endoribonuclease L-PSP 712128..712499 Brucella melitensis ATCC 23457 7671229 YP_002734493.1 CDS BMEA_B0729 NC_012442.1 712526 713995 D hypothetical protein 712526..713995 Brucella melitensis ATCC 23457 7671230 YP_002734494.1 CDS BMEA_B0730 NC_012442.1 714154 714396 R hypothetical protein complement(714154..714396) Brucella melitensis ATCC 23457 7671231 YP_002734495.1 CDS BMEA_B0731 NC_012442.1 714454 715248 R ABC transporter complement(714454..715248) Brucella melitensis ATCC 23457 7671232 YP_002734496.1 CDS BMEA_B0732 NC_012442.1 715245 716288 R transport system permease complement(715245..716288) Brucella melitensis ATCC 23457 7671233 YP_002734497.1 CDS BMEA_B0733 NC_012442.1 716285 717319 R periplasmic binding protein complement(716285..717319) Brucella melitensis ATCC 23457 7671234 YP_002734498.1 CDS BMEA_B0736 NC_012442.1 717870 718736 R p-hydroxybenzoic acid efflux pump subunit aaeA complement(717870..718736) Brucella melitensis ATCC 23457 7671235 YP_002734499.1 CDS BMEA_B0737 NC_012442.1 718733 718942 R hypothetical protein complement(718733..718942) Brucella melitensis ATCC 23457 7671236 YP_002734500.1 CDS BMEA_B0738 NC_012442.1 718969 721065 R Fusaric acid resistance protein conserved protein complement(718969..721065) Brucella melitensis ATCC 23457 7671237 YP_002734501.1 CDS BMEA_B0739 NC_012442.1 721108 721545 R MarR family transcriptional regulator complement(721108..721545) Brucella melitensis ATCC 23457 7671238 YP_002734502.1 CDS BMEA_B0740 NC_012442.1 721813 722541 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 721813..722541 Brucella melitensis ATCC 23457 7671239 YP_002734503.1 CDS BMEA_B0741 NC_012442.1 722641 724014 D glutamate--cysteine ligase 722641..724014 Brucella melitensis ATCC 23457 7671240 YP_002734504.1 CDS xseA NC_012442.1 724080 725615 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(724080..725615) Brucella melitensis ATCC 23457 7671241 YP_002734505.1 CDS BMEA_B0744 NC_012442.1 726818 727120 D hypothetical protein 726818..727120 Brucella melitensis ATCC 23457 7671243 YP_002734506.1 CDS BMEA_B0745 NC_012442.1 727114 727368 D hypothetical protein 727114..727368 Brucella melitensis ATCC 23457 7671244 YP_002734507.1 CDS BMEA_B0746 NC_012442.1 727372 728802 D glutamine synthetase 727372..728802 Brucella melitensis ATCC 23457 7671245 YP_002734508.1 CDS BMEA_B0747 NC_012442.1 728899 729216 D crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 728899..729216 Brucella melitensis ATCC 23457 7671246 YP_002734509.1 CDS BMEA_B0748 NC_012442.1 729270 730556 D FAD dependent oxidoreductase 729270..730556 Brucella melitensis ATCC 23457 7671247 YP_002734510.1 CDS BMEA_B0749 NC_012442.1 730567 730983 R MarR family transcriptional regulator complement(730567..730983) Brucella melitensis ATCC 23457 7671248 YP_002734511.1 CDS BMEA_B0750 NC_012442.1 731293 732093 R hypothetical protein complement(731293..732093) Brucella melitensis ATCC 23457 7671249 YP_002734512.1 CDS BMEA_B0751 NC_012442.1 732352 732816 R Leucine-responsive regulatory protein complement(732352..732816) Brucella melitensis ATCC 23457 7671250 YP_002734513.1 CDS BMEA_B0752 NC_012442.1 733192 733932 D AzlC family protein 733192..733932 Brucella melitensis ATCC 23457 7671251 YP_002734514.1 CDS BMEA_B0753 NC_012442.1 733929 734228 D branched-chain amino acid transport 733929..734228 Brucella melitensis ATCC 23457 7671252 YP_002734515.1 CDS BMEA_B0754 NC_012442.1 734251 735726 D major facilitator superfamily protein 734251..735726 Brucella melitensis ATCC 23457 7671253 YP_002734516.1 CDS fabG NC_012442.1 735815 736564 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(735815..736564) Brucella melitensis ATCC 23457 7671254 YP_002734517.1 CDS zwf NC_012442.1 736835 738310 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 736835..738310 Brucella melitensis ATCC 23457 7671255 YP_002734518.1 CDS pgl NC_012442.1 738439 739137 D 6-phosphogluconolactonase 738439..739137 Brucella melitensis ATCC 23457 7671256 YP_002734519.1 CDS edd NC_012442.1 739155 740996 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 739155..740996 Brucella melitensis ATCC 23457 7671257 YP_002734520.1 CDS BMEA_B0759 NC_012442.1 741088 741987 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(741088..741987) Brucella melitensis ATCC 23457 7671258 YP_002734521.1 CDS proC NC_012442.1 742308 743123 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 742308..743123 Brucella melitensis ATCC 23457 7671259 YP_002734522.1 CDS BMEA_B0761 NC_012442.1 743214 743966 R glutathione import ATP-binding protein GsiA complement(743214..743966) Brucella melitensis ATCC 23457 7671260 YP_002734523.1 CDS BMEA_B0763 NC_012442.1 744710 745540 R binding-protein-dependent transport systems inner membrane component complement(744710..745540) Brucella melitensis ATCC 23457 7671262 YP_002734524.1 CDS BMEA_B0764 NC_012442.1 745537 746535 R binding-protein-dependent transport systems inner membrane component complement(745537..746535) Brucella melitensis ATCC 23457 7671263 YP_002734525.1 CDS BMEA_B0765 NC_012442.1 746553 748166 R family 5 extracellular solute-binding protein complement(746553..748166) Brucella melitensis ATCC 23457 7671264 YP_002734526.1 CDS BMEA_B0766 NC_012442.1 748521 748865 D hypothetical protein 748521..748865 Brucella melitensis ATCC 23457 7671265 YP_002734527.1 CDS BMEA_B0767 NC_012442.1 749014 749673 D carbonate dehydratase 749014..749673 Brucella melitensis ATCC 23457 7671266 YP_002734528.1 CDS BMEA_B0768 NC_012442.1 749735 750145 R hypothetical protein complement(749735..750145) Brucella melitensis ATCC 23457 7671267 YP_002734529.1 CDS lysK NC_012442.1 750340 751995 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 750340..751995 Brucella melitensis ATCC 23457 7671268 YP_002734530.1 CDS BMEA_B0770 NC_012442.1 752083 753042 R hypothetical protein complement(752083..753042) Brucella melitensis ATCC 23457 7671269 YP_002734531.1 CDS BMEA_B0771 NC_012442.1 753043 753699 R Repressor protein C complement(753043..753699) Brucella melitensis ATCC 23457 7671270 YP_002734532.1 CDS BMEA_B0772 NC_012442.1 753937 756153 R Fatty acid oxidation complex subunit alpha complement(753937..756153) Brucella melitensis ATCC 23457 7671271 YP_002734533.1 CDS BMEA_B0773 NC_012442.1 756169 757377 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(756169..757377) Brucella melitensis ATCC 23457 7671272 YP_002734534.1 CDS BMEA_B0774 NC_012442.1 757442 759235 R acyl-CoA dehydrogenase domain-containing protein complement(757442..759235) Brucella melitensis ATCC 23457 7671273 YP_002734535.1 CDS BMEA_B0775 NC_012442.1 759210 759413 R hypothetical protein complement(759210..759413) Brucella melitensis ATCC 23457 7671274 YP_002734536.1 CDS BMEA_B0776 NC_012442.1 759545 759832 D hypothetical protein 759545..759832 Brucella melitensis ATCC 23457 7671275 YP_002734537.1 CDS BMEA_B0777 NC_012442.1 760136 760576 D LysR family transcriptional regulator 760136..760576 Brucella melitensis ATCC 23457 7671276 YP_002734538.1 CDS BMEA_B0778 NC_012442.1 761172 762338 D acyl-CoA dehydrogenase 761172..762338 Brucella melitensis ATCC 23457 7671277 YP_002734539.1 CDS nikE NC_012442.1 762471 763271 R with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE complement(762471..763271) Brucella melitensis ATCC 23457 7671278 YP_002734540.1 CDS nikD NC_012442.1 763268 764056 R with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD complement(763268..764056) Brucella melitensis ATCC 23457 7671279 YP_002734541.1 CDS nikC NC_012442.1 764053 764925 R with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC complement(764053..764925) Brucella melitensis ATCC 23457 7671280 YP_002734542.1 CDS nikB NC_012442.1 764922 765866 R with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB complement(764922..765866) Brucella melitensis ATCC 23457 7671281 YP_002734543.1 CDS nikA NC_012442.1 765868 767448 R nickel ABC transporter periplasmic nickel-binding protein complement(765868..767448) Brucella melitensis ATCC 23457 7671282 YP_002734544.1 CDS nikR NC_012442.1 767715 768113 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 767715..768113 Brucella melitensis ATCC 23457 7671283 YP_002734545.1 CDS BMEA_B0786 NC_012442.1 769745 770587 R ABC transporter permease complement(769745..770587) Brucella melitensis ATCC 23457 7671285 YP_002734546.1 CDS BMEA_B0789 NC_012442.1 772626 773807 R ABC transporter substrate-binding protein complement(772626..773807) Brucella melitensis ATCC 23457 7671288 YP_002734547.1 CDS BMEA_B0790 NC_012442.1 773967 775469 R mannitol dehydrogenase domain -containing protein complement(773967..775469) Brucella melitensis ATCC 23457 7671289 YP_002734548.1 CDS BMEA_B0792 NC_012442.1 777200 777973 D GntR family transcriptional regulator 777200..777973 Brucella melitensis ATCC 23457 7671291 YP_002734549.1 CDS uxuA NC_012442.1 778034 779239 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 778034..779239 Brucella melitensis ATCC 23457 7671292 YP_002734550.1 CDS BMEA_B0794 NC_012442.1 779423 782503 R putative multidrug efflux transporter protein complement(779423..782503) Brucella melitensis ATCC 23457 7671293 YP_002734551.1 CDS BMEA_B0795 NC_012442.1 782526 783512 R RND family efflux transporter MFP subunit complement(782526..783512) Brucella melitensis ATCC 23457 7671294 YP_002734552.1 CDS BMEA_B0796 NC_012442.1 783968 784369 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 783968..784369 Brucella melitensis ATCC 23457 7671295 YP_002734553.1 CDS BMEA_B0797 NC_012442.1 784357 784779 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 784357..784779 Brucella melitensis ATCC 23457 7671296 YP_002734554.1 CDS BMEA_B0798 NC_012442.1 784795 785154 D hypothetical protein 784795..785154 Brucella melitensis ATCC 23457 7671297 YP_002734555.1 CDS BMEA_B0799 NC_012442.1 785209 785637 R transcriptional regulator MerR family protein complement(785209..785637) Brucella melitensis ATCC 23457 7671298 YP_002734556.1 CDS BMEA_B0800 NC_012442.1 785898 786035 R hypothetical protein complement(785898..786035) Brucella melitensis ATCC 23457 7671299 YP_002734557.1 CDS BMEA_B0801 NC_012442.1 786034 788883 D peptidoglycan-binding domain 1 protein 786034..788883 Brucella melitensis ATCC 23457 7671300 YP_002734558.1 CDS BMEA_B0802 NC_012442.1 789120 790070 D hypothetical protein 789120..790070 Brucella melitensis ATCC 23457 7671301 YP_002734559.1 CDS BMEA_B0803 NC_012442.1 790105 790896 D hypothetical protein 790105..790896 Brucella melitensis ATCC 23457 7671302 YP_002734560.1 CDS BMEA_B0804 NC_012442.1 790994 791710 R hypothetical protein complement(790994..791710) Brucella melitensis ATCC 23457 7671303 YP_002734561.1 CDS BMEA_B0805 NC_012442.1 791707 794262 R hypothetical protein complement(791707..794262) Brucella melitensis ATCC 23457 7671304 YP_002734562.1 CDS BMEA_B0806 NC_012442.1 794272 794418 R hypothetical protein complement(794272..794418) Brucella melitensis ATCC 23457 7671305 YP_002734563.1 CDS BMEA_B0807 NC_012442.1 794514 795536 R hypothetical protein complement(794514..795536) Brucella melitensis ATCC 23457 7671306 YP_002734564.1 CDS BMEA_B0808 NC_012442.1 795735 795896 R hypothetical protein complement(795735..795896) Brucella melitensis ATCC 23457 7671307 YP_002734565.1 CDS BMEA_B0809 NC_012442.1 796043 797011 D 2-nitropropane dioxygenase NPD 796043..797011 Brucella melitensis ATCC 23457 7671308 YP_002734566.1 CDS BMEA_B0810 NC_012442.1 797070 797207 D hypothetical protein 797070..797207 Brucella melitensis ATCC 23457 7671309 YP_002734567.1 CDS BMEA_B0812 NC_012442.1 798066 798788 D hypothetical protein 798066..798788 Brucella melitensis ATCC 23457 7671311 YP_002734568.1 CDS BMEA_B0813 NC_012442.1 798795 799295 R hypothetical protein complement(798795..799295) Brucella melitensis ATCC 23457 7671312 YP_002734569.1 CDS BMEA_B0814 NC_012442.1 799434 799550 D hypothetical protein 799434..799550 Brucella melitensis ATCC 23457 7671313 YP_002734570.1 CDS BMEA_B0815 NC_012442.1 799846 800043 R hypothetical protein complement(799846..800043) Brucella melitensis ATCC 23457 7671314 YP_002734571.1 CDS BMEA_B0816 NC_012442.1 800112 800267 D hypothetical protein 800112..800267 Brucella melitensis ATCC 23457 7671315 YP_002734572.1 CDS BMEA_B0817 NC_012442.1 801061 801201 R hypothetical protein complement(801061..801201) Brucella melitensis ATCC 23457 7671316 YP_002734573.1 CDS BMEA_B0818 NC_012442.1 801362 801994 D hypothetical protein 801362..801994 Brucella melitensis ATCC 23457 7671317 YP_002734574.1 CDS hsdM NC_012442.1 802002 803528 D type I restriction-modification system, M subunit 802002..803528 Brucella melitensis ATCC 23457 7671318 YP_002734575.1 CDS BMEA_B0820 NC_012442.1 803518 804741 D type I restriction enzyme specificity protein 803518..804741 Brucella melitensis ATCC 23457 7671319 YP_002734576.1 CDS hsdR NC_012442.1 804738 807707 D type I site-specific deoxyribonuclease, HsdR family protein 804738..807707 Brucella melitensis ATCC 23457 7671320 YP_002734577.1 CDS BMEA_B0822 NC_012442.1 807704 808444 D hypothetical protein 807704..808444 Brucella melitensis ATCC 23457 7671321 YP_002734578.1 CDS BMEA_B0823 NC_012442.1 808452 809381 D hypothetical protein 808452..809381 Brucella melitensis ATCC 23457 7671322 YP_002734579.1 CDS BMEA_B0824 NC_012442.1 809368 811263 D hypothetical protein 809368..811263 Brucella melitensis ATCC 23457 7671323 YP_002734580.1 CDS BMEA_B0825 NC_012442.1 811777 812145 D transposase 811777..812145 Brucella melitensis ATCC 23457 7671324 YP_002734581.1 CDS BMEA_B0826 NC_012442.1 812142 812534 D transposase, IS4 812142..812534 Brucella melitensis ATCC 23457 7671325 YP_002734582.1 CDS BMEA_B0827 NC_012442.1 812548 812682 R hypothetical protein complement(812548..812682) Brucella melitensis ATCC 23457 7671326 YP_002734583.1 CDS BMEA_B0828 NC_012442.1 812944 813390 D hypothetical protein 812944..813390 Brucella melitensis ATCC 23457 7671327 YP_002734584.1 CDS BMEA_B0829 NC_012442.1 813501 815186 D hypothetical protein 813501..815186 Brucella melitensis ATCC 23457 7671328 YP_002734585.1 CDS BMEA_B0830 NC_012442.1 815350 816804 R Putrescine aminotransferase complement(815350..816804) Brucella melitensis ATCC 23457 7671329 YP_002734586.1 CDS BMEA_B0831 NC_012442.1 816815 817825 R UDP-glucuronic acid decarboxylase 1 complement(816815..817825) Brucella melitensis ATCC 23457 7671330 YP_002734587.1 CDS BMEA_B0832 NC_012442.1 817874 818293 R hypothetical protein complement(817874..818293) Brucella melitensis ATCC 23457 7671331 YP_002734588.1 CDS BMEA_B0833 NC_012442.1 818325 819659 R FAD linked oxidase domain-containing protein complement(818325..819659) Brucella melitensis ATCC 23457 7671332 YP_002734589.1 CDS BMEA_B0834 NC_012442.1 819659 821098 R hypothetical protein complement(819659..821098) Brucella melitensis ATCC 23457 7671333 YP_002734590.1 CDS BMEA_B0835 NC_012442.1 821721 822542 R Lactose phosphotransferase system repressor complement(821721..822542) Brucella melitensis ATCC 23457 7671334 YP_002734591.1 CDS BMEA_B0836 NC_012442.1 822750 823697 R rhizopine-binding protein complement(822750..823697) Brucella melitensis ATCC 23457 7671335 YP_002734592.1 CDS BMEA_B0837 NC_012442.1 823864 824904 R hypothetical protein complement(823864..824904) Brucella melitensis ATCC 23457 7671336 YP_002734593.1 CDS BMEA_B0838 NC_012442.1 824928 826472 R Xylose import ATP-binding protein xylG complement(824928..826472) Brucella melitensis ATCC 23457 7671337 YP_002734594.1 CDS BMEA_B0839 NC_012442.1 826469 827125 R hypothetical protein complement(826469..827125) Brucella melitensis ATCC 23457 7671338 YP_002734595.1 CDS BMEA_B0840 NC_012442.1 827105 827272 D hypothetical protein 827105..827272 Brucella melitensis ATCC 23457 7671339 YP_002734596.1 CDS BMEA_B0841 NC_012442.1 827225 827401 R hypothetical protein complement(827225..827401) Brucella melitensis ATCC 23457 7671340 YP_002734597.1 CDS BMEA_B0842 NC_012442.1 827724 827876 D hypothetical protein 827724..827876 Brucella melitensis ATCC 23457 7671341 YP_002734598.1 CDS BMEA_B0843 NC_012442.1 827869 829422 D carbohydrate kinase FGGY 827869..829422 Brucella melitensis ATCC 23457 7671342 YP_002734599.1 CDS BMEA_B0844 NC_012442.1 829435 830943 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 829435..830943 Brucella melitensis ATCC 23457 7671343 YP_002734600.1 CDS BMEA_B0845 NC_012442.1 830951 831883 D hypothetical protein 830951..831883 Brucella melitensis ATCC 23457 7671344 YP_002734601.1 CDS BMEA_B0846 NC_012442.1 831911 832861 D DeoR family transcriptional regulator 831911..832861 Brucella melitensis ATCC 23457 7671345 YP_002734602.1 CDS BMEA_B0847 NC_012442.1 832949 833713 D DeoR family transcriptional regulator 832949..833713 Brucella melitensis ATCC 23457 7671346 YP_002734603.1 CDS tpiA NC_012442.1 833726 834496 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 833726..834496 Brucella melitensis ATCC 23457 7671347 YP_002734604.1 CDS BMEA_B0849 NC_012442.1 834508 834963 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 834508..834963 Brucella melitensis ATCC 23457 7671348 YP_002734605.1 CDS fba NC_012442.1 835030 836094 R class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase complement(835030..836094) Brucella melitensis ATCC 23457 7671349 YP_002734606.1 CDS BMEA_B0851 NC_012442.1 836125 837147 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(836125..837147) Brucella melitensis ATCC 23457 7671350 YP_002734607.1 CDS BMEA_B0852 NC_012442.1 837144 837383 R hypothetical protein complement(837144..837383) Brucella melitensis ATCC 23457 7671351 YP_002734608.1 CDS BMEA_B0853 NC_012442.1 837581 838198 R hypothetical protein complement(837581..838198) Brucella melitensis ATCC 23457 7671352 YP_002734609.1 CDS typA NC_012442.1 838320 840146 R GTP-binding protein TypA complement(838320..840146) Brucella melitensis ATCC 23457 7671353 YP_002734610.1 CDS mgtE NC_012442.1 840389 841786 R magnesium transporter complement(840389..841786) Brucella melitensis ATCC 23457 7671354 YP_002734611.1 CDS BMEA_B0856 NC_012442.1 841853 842017 R hypothetical protein complement(841853..842017) Brucella melitensis ATCC 23457 7671355 YP_002734612.1 CDS BMEA_B0857 NC_012442.1 842112 844160 D peptidyl-dipeptidase Dcp 842112..844160 Brucella melitensis ATCC 23457 7671356 YP_002734613.1 CDS BMEA_B0858 NC_012442.1 844190 844543 R glyoxalase/bleomycin resistance protein/dioxygenase complement(844190..844543) Brucella melitensis ATCC 23457 7671357 YP_002734614.1 CDS BMEA_B0859 NC_012442.1 844543 844749 R hypothetical protein complement(844543..844749) Brucella melitensis ATCC 23457 7671358 YP_002734615.1 CDS BMEA_B0860 NC_012442.1 844767 845765 R citrate lyase subunit beta complement(844767..845765) Brucella melitensis ATCC 23457 7671359 YP_002734616.1 CDS BMEA_B0861 NC_012442.1 845796 846002 D hypothetical protein 845796..846002 Brucella melitensis ATCC 23457 7671360 YP_002734617.1 CDS leuD NC_012442.1 846067 846672 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 846067..846672 Brucella melitensis ATCC 23457 7671361 YP_002734618.1 CDS BMEA_B0863 NC_012442.1 846758 847180 D hypothetical protein 846758..847180 Brucella melitensis ATCC 23457 7671362 YP_002734619.1 CDS BMEA_B0864 NC_012442.1 847231 847653 R OsmC family protein complement(847231..847653) Brucella melitensis ATCC 23457 7671363 YP_002734620.1 CDS BMEA_B0865 NC_012442.1 847859 848314 D MarR family transcriptional regulator 847859..848314 Brucella melitensis ATCC 23457 7671364 YP_002734621.1 CDS asd NC_012442.1 848378 849412 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(848378..849412) Brucella melitensis ATCC 23457 7671365 YP_002734622.1 CDS BMEA_B0867 NC_012442.1 849935 851833 D major facilitator superfamily protein 849935..851833 Brucella melitensis ATCC 23457 7671366 YP_002734623.1 CDS BMEA_B0868 NC_012442.1 851891 852943 R methylated-DNA-protein-cysteine methyltransferase complement(851891..852943) Brucella melitensis ATCC 23457 7671367 YP_002734624.1 CDS leuB NC_012442.1 853084 854196 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(853084..854196) Brucella melitensis ATCC 23457 7671368 YP_002734625.1 CDS BMEA_B0871 NC_012442.1 854496 854690 R hypothetical protein complement(854496..854690) Brucella melitensis ATCC 23457 7671369 YP_002734626.1 CDS BMEA_B0872 NC_012442.1 854867 855571 R peptidase S16 lon domain-containing protein complement(854867..855571) Brucella melitensis ATCC 23457 7671370 YP_002734627.1 CDS trx NC_012442.1 855635 856609 R thioredoxin complement(855635..856609) Brucella melitensis ATCC 23457 7671371 YP_002734628.1 CDS BMEA_B0874 NC_012442.1 856857 857399 R YbaK/prolyl-tRNA synthetase associated protein complement(856857..857399) Brucella melitensis ATCC 23457 7671372 YP_002734629.1 CDS BMEA_B0875 NC_012442.1 857407 857598 R hypothetical protein complement(857407..857598) Brucella melitensis ATCC 23457 7671373 YP_002734630.1 CDS BMEA_B0877 NC_012442.1 857814 858323 R hypothetical protein complement(857814..858323) Brucella melitensis ATCC 23457 7671375 YP_002734631.1 CDS BMEA_B0879 NC_012442.1 858395 858820 D SEC-independent protein translocase protein TatC 858395..858820 Brucella melitensis ATCC 23457 7671376 YP_002734632.1 CDS BMEA_B0880 NC_012442.1 858833 859909 R catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase complement(858833..859909) Brucella melitensis ATCC 23457 7671377 YP_002734633.1 CDS rocF NC_012442.1 859948 860868 R arginase complement(859948..860868) Brucella melitensis ATCC 23457 7671378 YP_002734634.1 CDS BMEA_B0882 NC_012442.1 860999 861436 D hypothetical protein 860999..861436 Brucella melitensis ATCC 23457 7671379 YP_002734635.1 CDS BMEA_B0883 NC_012442.1 861474 862589 R NADH:flavin oxidoreductase/NADH oxidase complement(861474..862589) Brucella melitensis ATCC 23457 7671380 YP_002734636.1 CDS BMEA_B0884 NC_012442.1 862633 862941 R regulatory protein ArsR complement(862633..862941) Brucella melitensis ATCC 23457 7671381 YP_002734637.1 CDS BMEA_B0886 NC_012442.1 865557 866840 R FAD dependent oxidoreductase complement(865557..866840) Brucella melitensis ATCC 23457 7671383 YP_002734638.1 CDS BMEA_B0887 NC_012442.1 866940 867872 R hypothetical protein complement(866940..867872) Brucella melitensis ATCC 23457 7671384 YP_002734639.1 CDS BMEA_B0890 NC_012442.1 868796 870328 D aldehyde dehydrogenase family 7 member a1 868796..870328 Brucella melitensis ATCC 23457 7671386 YP_002734640.1 CDS purU NC_012442.1 870552 871436 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(870552..871436) Brucella melitensis ATCC 23457 7671387 YP_002734641.1 CDS BMEA_B0892 NC_012442.1 871580 872308 R hypothetical protein complement(871580..872308) Brucella melitensis ATCC 23457 7671388 YP_002734642.1 CDS nagA NC_012442.1 872316 873482 R N-acetylglucosamine-6-phosphate deacetylase complement(872316..873482) Brucella melitensis ATCC 23457 7671389 YP_002734643.1 CDS BMEA_B0894 NC_012442.1 873479 874510 R Sugar isomerase SIS complement(873479..874510) Brucella melitensis ATCC 23457 7671390 YP_002734644.1 CDS BMEA_B0895 NC_012442.1 874513 875280 R GntR family transcriptional regulator complement(874513..875280) Brucella melitensis ATCC 23457 7671391 YP_002734645.1 CDS BMEA_B0896 NC_012442.1 875383 878457 R acriflavin resistance protein complement(875383..878457) Brucella melitensis ATCC 23457 7671392 YP_002734646.1 CDS BMEA_B0897 NC_012442.1 878454 879560 R RND family efflux transporter MFP subunit complement(878454..879560) Brucella melitensis ATCC 23457 7671393 YP_002734647.1 CDS BMEA_B0898 NC_012442.1 879557 880675 R RND family efflux transporter MFP subunit complement(879557..880675) Brucella melitensis ATCC 23457 7671394 YP_002734648.1 CDS BMEA_B0899 NC_012442.1 880806 880922 R hypothetical protein complement(880806..880922) Brucella melitensis ATCC 23457 7671395 YP_002734649.1 CDS BMEA_B0900 NC_012442.1 880961 881260 R hypothetical protein complement(880961..881260) Brucella melitensis ATCC 23457 7671396 YP_002734650.1 CDS BMEA_B0901 NC_012442.1 881257 883569 R oxidoreductase alpha, molybdopterin subunit complement(881257..883569) Brucella melitensis ATCC 23457 7671397 YP_002734651.1 CDS BMEA_B0902 NC_012442.1 883774 884919 D FMN-dependent dehydrogenase 883774..884919 Brucella melitensis ATCC 23457 7671398 YP_002734652.1 CDS BMEA_B0903 NC_012442.1 885198 886052 D outer surface protein 885198..886052 Brucella melitensis ATCC 23457 7671399 YP_002734653.1 CDS BMEA_B0904 NC_012442.1 886200 886667 R Leucine-responsive regulatory protein complement(886200..886667) Brucella melitensis ATCC 23457 7671400 YP_002734654.1 CDS alr NC_012442.1 886917 888107 D alanine racemase 886917..888107 Brucella melitensis ATCC 23457 7671401 YP_002734655.1 CDS BMEA_B0906 NC_012442.1 888123 889373 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 888123..889373 Brucella melitensis ATCC 23457 7671402 YP_002734656.1 CDS BMEA_B0907 NC_012442.1 889416 889964 R hypothetical protein complement(889416..889964) Brucella melitensis ATCC 23457 7671403 YP_002734657.1 CDS BMEA_B0908 NC_012442.1 890091 890216 R hypothetical protein complement(890091..890216) Brucella melitensis ATCC 23457 7671404 YP_002734658.1 CDS BMEA_B0909 NC_012442.1 890534 891439 D Omega-amino acid--pyruvate aminotransferase 890534..891439 Brucella melitensis ATCC 23457 7671405 YP_002734659.1 CDS hutC NC_012442.1 891510 892253 R histidine utilization repressor complement(891510..892253) Brucella melitensis ATCC 23457 7671406 YP_002734660.1 CDS hutF NC_012442.1 892265 893629 R catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase complement(892265..893629) Brucella melitensis ATCC 23457 7671407 YP_002734661.1 CDS BMEA_B0912 NC_012442.1 893642 893800 R hypothetical protein complement(893642..893800) Brucella melitensis ATCC 23457 7671408 YP_002734662.1 CDS hutI NC_012442.1 893760 895931 D catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 893760..895931 Brucella melitensis ATCC 23457 7671409 YP_002734663.1 CDS hutG NC_012442.1 896538 897338 D N-formylglutamate amidohydrolase 896538..897338 Brucella melitensis ATCC 23457 7671411 YP_002734664.1 CDS hutU NC_012442.1 897349 899022 D catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 897349..899022 Brucella melitensis ATCC 23457 7671412 YP_002734665.1 CDS BMEA_B0917 NC_012442.1 899029 899652 D hypothetical protein 899029..899652 Brucella melitensis ATCC 23457 7671413 YP_002734666.1 CDS BMEA_B0918 NC_012442.1 899740 900621 D catalyzes the transamination of D-amino acids and their alpha-keto acids; D-amino acid aminotransferase 899740..900621 Brucella melitensis ATCC 23457 7671414 YP_002734667.1 CDS BMEA_B0919 NC_012442.1 900772 901962 R monosaccharide-transporting ATPase complement(900772..901962) Brucella melitensis ATCC 23457 7671415 YP_002734668.1 CDS BMEA_B0920 NC_012442.1 901962 903551 R L-arabinose transport ATP-binding protein araG complement(901962..903551) Brucella melitensis ATCC 23457 7671416 YP_002734669.1 CDS BMEA_B0921 NC_012442.1 903564 903704 D hypothetical protein 903564..903704 Brucella melitensis ATCC 23457 7671417 YP_002734670.1 CDS BMEA_B0923 NC_012442.1 904906 905538 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(904906..905538) Brucella melitensis ATCC 23457 7671419 YP_002734671.1 CDS BMEA_B0924 NC_012442.1 905535 906464 R 2-keto-3-deoxy-galactonokinase complement(905535..906464) Brucella melitensis ATCC 23457 7671420 YP_002734672.1 CDS BMEA_B0925 NC_012442.1 906479 908284 R catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase complement(906479..908284) Brucella melitensis ATCC 23457 7671421 YP_002734673.1 CDS BMEA_B0926 NC_012442.1 908381 909316 R Galactose 1-dehydrogenase complement(908381..909316) Brucella melitensis ATCC 23457 7671422 YP_002734674.1 CDS BMEA_B0927 NC_012442.1 909325 910317 R hypothetical protein complement(909325..910317) Brucella melitensis ATCC 23457 7671423 YP_002734675.1 CDS BMEA_B0928 NC_012442.1 910587 910880 D inner membrane ABC transporter permease YjfF 910587..910880 Brucella melitensis ATCC 23457 7671424 YP_002734676.1 CDS BMEA_B0929 NC_012442.1 910905 911630 D hypothetical protein 910905..911630 Brucella melitensis ATCC 23457 7671425 YP_002734677.1 CDS BMEA_B0930 NC_012442.1 911643 913337 R thiamine pyrophosphate protein complement(911643..913337) Brucella melitensis ATCC 23457 7671426 YP_002734678.1 CDS BMEA_B0931 NC_012442.1 913454 913582 R hypothetical protein complement(913454..913582) Brucella melitensis ATCC 23457 7671427 YP_002734679.1 CDS BMEA_B0932 NC_012442.1 913586 913699 D hypothetical protein 913586..913699 Brucella melitensis ATCC 23457 7671428 YP_002734680.1 CDS BMEA_B0933 NC_012442.1 913744 915300 D intracellular enzymes acting on low molecular weight D-amino acid amides, esters and oligopeptides containing D-amino acids; these proteases release the N-terminal D-amino acid from a peptide, and show higher affinity for D-Ala, D-Ser or D-Thr; no preference for the stereochemistry of the second amino acid; D-aminopeptidase 913744..915300 Brucella melitensis ATCC 23457 7671429 YP_002734681.1 CDS BMEA_B0934 NC_012442.1 915331 916350 R amino acid ABC transporter substrate-binding protein complement(915331..916350) Brucella melitensis ATCC 23457 7671430 YP_002734682.1 CDS BMEA_B0936 NC_012442.1 919621 919779 R hypothetical protein complement(919621..919779) Brucella melitensis ATCC 23457 7671432 YP_002734683.1 CDS BMEA_B0937 NC_012442.1 919778 920218 D hypothetical protein 919778..920218 Brucella melitensis ATCC 23457 7671433 YP_002734684.1 CDS BMEA_B0938 NC_012442.1 920434 921348 R LysR family transcriptional regulator complement(920434..921348) Brucella melitensis ATCC 23457 7671434 YP_002734685.1 CDS BMEA_B0939 NC_012442.1 921613 922770 D hypothetical protein 921613..922770 Brucella melitensis ATCC 23457 7671435 YP_002734686.1 CDS BMEA_B0940 NC_012442.1 922783 923598 D ABC transporter 922783..923598 Brucella melitensis ATCC 23457 7671436 YP_002734687.1 CDS BMEA_B0941 NC_012442.1 923591 924316 D ABC transporter 923591..924316 Brucella melitensis ATCC 23457 7671437 YP_002734688.1 CDS BMEA_B0942 NC_012442.1 924321 925208 D hypothetical protein 924321..925208 Brucella melitensis ATCC 23457 7671438 YP_002734689.1 CDS BMEA_B0943 NC_012442.1 925210 926205 D inner-membrane translocator 925210..926205 Brucella melitensis ATCC 23457 7671439 YP_002734690.1 CDS BMEA_B0944 NC_012442.1 926269 927867 D choline dehydrogenase 926269..927867 Brucella melitensis ATCC 23457 7671440 YP_002734691.1 CDS BMEA_B0945 NC_012442.1 927864 928007 D hypothetical protein 927864..928007 Brucella melitensis ATCC 23457 7671441 YP_002734692.1 CDS BMEA_B0946 NC_012442.1 928101 928937 D lipoprotein, YaeC family protein 928101..928937 Brucella melitensis ATCC 23457 7671442 YP_002734693.1 CDS BMEA_B0947 NC_012442.1 929402 930460 D methionine import ATP-binding protein MetN 929402..930460 Brucella melitensis ATCC 23457 7671443 YP_002734694.1 CDS BMEA_B0948 NC_012442.1 930441 931106 D D-methionine transport system permease metI 930441..931106 Brucella melitensis ATCC 23457 7671444 YP_002734695.1 CDS BMEA_B0949 NC_012442.1 931119 931526 R glyoxalase/bleomycin resistance protein/dioxygenase complement(931119..931526) Brucella melitensis ATCC 23457 7671445 YP_002734696.1 CDS BMEA_B0950 NC_012442.1 931618 932505 R TPR repeat-containing protein complement(931618..932505) Brucella melitensis ATCC 23457 7671446 YP_002734697.1 CDS BMEA_B0951 NC_012442.1 932497 932760 D hypothetical protein 932497..932760 Brucella melitensis ATCC 23457 7671447 YP_002734698.1 CDS rpsU NC_012442.1 933044 933271 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(933044..933271) Brucella melitensis ATCC 23457 7671448 YP_002734699.1 CDS BMEA_B0954 NC_012442.1 934894 935370 R MaoC domain-containing protein dehydratase complement(934894..935370) Brucella melitensis ATCC 23457 7671450 YP_002734700.1 CDS BMEA_B0955 NC_012442.1 935445 936116 R HAD-superfamily hydrolase complement(935445..936116) Brucella melitensis ATCC 23457 7671451 YP_002734701.1 CDS BMEA_B0956 NC_012442.1 936312 937628 D homoserine dehydrogenase NAD-binding 936312..937628 Brucella melitensis ATCC 23457 7671452 YP_002734702.1 CDS BMEA_B0957 NC_012442.1 937714 939114 R hypothetical protein complement(937714..939114) Brucella melitensis ATCC 23457 7671453 YP_002734703.1 CDS BMEA_B0958 NC_012442.1 939127 939546 R hypothetical protein complement(939127..939546) Brucella melitensis ATCC 23457 7671454 YP_002734704.1 CDS BMEA_B0959 NC_012442.1 939546 940847 R alanine dehydrogenase/PNT domain-containing protein complement(939546..940847) Brucella melitensis ATCC 23457 7671455 YP_002734705.1 CDS BMEA_B0960 NC_012442.1 941071 941295 R aa3 type cytochrome c oxidase subunit IV complement(941071..941295) Brucella melitensis ATCC 23457 7671456 YP_002734706.1 CDS BMEA_B0962 NC_012442.1 942516 943733 R 6-aminohexanoate-dimer hydrolase complement(942516..943733) Brucella melitensis ATCC 23457 7671458 YP_002734707.1 CDS BMEA_B0963 NC_012442.1 943985 946282 R GGDEF domain-containing protein complement(943985..946282) Brucella melitensis ATCC 23457 7671459 YP_002734708.1 CDS BMEA_B0964 NC_012442.1 946527 946667 R hypothetical protein complement(946527..946667) Brucella melitensis ATCC 23457 7671460 YP_002734709.1 CDS BMEA_B0965 NC_012442.1 946648 947397 R glucose 1-dehydrogenase 3 complement(946648..947397) Brucella melitensis ATCC 23457 7671461 YP_002734710.1 CDS BMEA_B0966 NC_012442.1 947632 948405 D peptidase C26 947632..948405 Brucella melitensis ATCC 23457 7671462 YP_002734711.1 CDS BMEA_B0967 NC_012442.1 948555 949529 R D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding complement(948555..949529) Brucella melitensis ATCC 23457 7671463 YP_002734712.1 CDS BMEA_B0968 NC_012442.1 949615 950634 R HTH-type transcriptional repressor PurR complement(949615..950634) Brucella melitensis ATCC 23457 7671464 YP_002734713.1 CDS BMEA_B0969 NC_012442.1 950781 951038 R MarR family transcriptional regulator complement(950781..951038) Brucella melitensis ATCC 23457 7671465 YP_002734714.1 CDS BMEA_B0970 NC_012442.1 951045 951272 R MarR family transcriptional regulator complement(951045..951272) Brucella melitensis ATCC 23457 7671466 YP_002734715.1 CDS BMEA_B0971 NC_012442.1 951451 952221 D creatininase 951451..952221 Brucella melitensis ATCC 23457 7671467 YP_002734716.1 CDS BMEA_B0972 NC_012442.1 952457 953590 D cobalamin synthesis protein P47K 952457..953590 Brucella melitensis ATCC 23457 7671468 YP_002734717.1 CDS BMEA_B0973 NC_012442.1 953709 954683 D WD-repeat family protein 953709..954683 Brucella melitensis ATCC 23457 7671469 YP_002734718.1 CDS BMEA_B0974 NC_012442.1 954888 955754 R hypothetical protein complement(954888..955754) Brucella melitensis ATCC 23457 7671470 YP_002734719.1 CDS BMEA_B0975 NC_012442.1 956177 957136 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 956177..957136 Brucella melitensis ATCC 23457 7671471 YP_002734720.1 CDS BMEA_B0976 NC_012442.1 957138 957800 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 957138..957800 Brucella melitensis ATCC 23457 7671472 YP_002734721.1 CDS BMEA_B0977 NC_012442.1 958008 958352 R hypothetical protein complement(958008..958352) Brucella melitensis ATCC 23457 7671473 YP_002734722.1 CDS BMEA_B0978 NC_012442.1 958427 959380 R monosaccharide-transporting ATPase complement(958427..959380) Brucella melitensis ATCC 23457 7671474 YP_002734723.1 CDS BMEA_B0979 NC_012442.1 959377 960336 R inner-membrane translocator complement(959377..960336) Brucella melitensis ATCC 23457 7671475 YP_002734724.1 CDS BMEA_B0981 NC_012442.1 961774 962943 R rhizopine-binding protein complement(961774..962943) Brucella melitensis ATCC 23457 7671477 YP_002734725.1 CDS BMEA_B0982 NC_012442.1 963245 964039 D Pectin degradation repressor protein kdgR 963245..964039 Brucella melitensis ATCC 23457 7671478 YP_002734726.1 CDS BMEA_B0983 NC_012442.1 964133 965314 R hypothetical protein complement(964133..965314) Brucella melitensis ATCC 23457 7671479 YP_002734727.1 CDS BMEA_B0984 NC_012442.1 965482 967512 R TonB-dependent copper receptor complement(965482..967512) Brucella melitensis ATCC 23457 7671480 YP_002734728.1 CDS BMEA_B0985 NC_012442.1 967609 968016 R hypothetical protein complement(967609..968016) Brucella melitensis ATCC 23457 7671481 YP_002734729.1 CDS BMEA_B0986 NC_012442.1 968169 968555 R glyoxalase domain-containing protein 5 complement(968169..968555) Brucella melitensis ATCC 23457 7671482 YP_002734730.1 CDS BMEA_B0987 NC_012442.1 968738 969343 R glutathione S-transferase complement(968738..969343) Brucella melitensis ATCC 23457 7671483 YP_002734731.1 CDS BMEA_B0988 NC_012442.1 969447 970748 R hypothetical protein complement(969447..970748) Brucella melitensis ATCC 23457 7671484 YP_002734732.1 CDS BMEA_B0990 NC_012442.1 972232 973464 R catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase complement(972232..973464) Brucella melitensis ATCC 23457 7671486 YP_002734733.1 CDS BMEA_B0991 NC_012442.1 973620 974618 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 973620..974618 Brucella melitensis ATCC 23457 7671487 YP_002734734.1 CDS BMEA_B0992 NC_012442.1 974694 976082 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(974694..976082) Brucella melitensis ATCC 23457 7671488 YP_002734735.1 CDS BMEA_B0993 NC_012442.1 976096 976944 R oligopeptide transport ATP-binding protein oppF complement(976096..976944) Brucella melitensis ATCC 23457 7671489 YP_002734736.1 CDS BMEA_B0994 NC_012442.1 976941 977966 R peptide ABC transporter ATPase complement(976941..977966) Brucella melitensis ATCC 23457 7671490 YP_002734737.1 CDS BMEA_B0995 NC_012442.1 977963 978823 R dipeptide transport system permease DppC complement(977963..978823) Brucella melitensis ATCC 23457 7671491 YP_002734738.1 CDS BMEA_B0996 NC_012442.1 978820 979773 R hypothetical protein complement(978820..979773) Brucella melitensis ATCC 23457 7671492 YP_002734739.1 CDS BMEA_B0997 NC_012442.1 979871 981349 R glutathione-binding protein GsiB complement(979871..981349) Brucella melitensis ATCC 23457 7671493 YP_002734740.1 CDS fabG NC_012442.1 981372 982130 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(981372..982130) Brucella melitensis ATCC 23457 7671494 YP_002734741.1 CDS BMEA_B0999 NC_012442.1 982165 983652 R aldehyde dehydrogenase complement(982165..983652) Brucella melitensis ATCC 23457 7671495 YP_002734742.1 CDS BMEA_B1000 NC_012442.1 983636 984322 R GntR family transcriptional regulator complement(983636..984322) Brucella melitensis ATCC 23457 7671496 YP_002734743.1 CDS BMEA_B1001 NC_012442.1 984422 984568 R hypothetical protein complement(984422..984568) Brucella melitensis ATCC 23457 7671497 YP_002734744.1 CDS BMEA_B1002 NC_012442.1 984692 986071 D drug resistance transporter, EmrB/QacA subfamily protein 984692..986071 Brucella melitensis ATCC 23457 7671498 YP_002734745.1 CDS BMEA_B1004 NC_012442.1 986465 987532 D hypothetical protein 986465..987532 Brucella melitensis ATCC 23457 7671500 YP_002734746.1 CDS BMEA_B1005 NC_012442.1 987586 987930 R endoribonuclease L-PSP complement(987586..987930) Brucella melitensis ATCC 23457 7671501 YP_002734747.1 CDS BMEA_B1006 NC_012442.1 988013 988237 D hypothetical protein 988013..988237 Brucella melitensis ATCC 23457 7671502 YP_002734748.1 CDS rpmH NC_012442.1 988238 988372 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 988238..988372 Brucella melitensis ATCC 23457 7671503 YP_002734749.1 CDS rnpA NC_012442.1 988422 988847 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 988422..988847 Brucella melitensis ATCC 23457 7671504 YP_002734750.1 CDS BMEA_B1009 NC_012442.1 988837 990669 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 988837..990669 Brucella melitensis ATCC 23457 7671505 YP_002734751.1 CDS engB NC_012442.1 990711 991514 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 990711..991514 Brucella melitensis ATCC 23457 7671506 YP_002734752.1 CDS argB NC_012442.1 991685 992575 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 991685..992575 Brucella melitensis ATCC 23457 7671507 YP_002734753.1 CDS BMEA_B1012 NC_012442.1 992649 993353 D pyrimidine 5'-nucleotidase 992649..993353 Brucella melitensis ATCC 23457 7671508 YP_002734754.1 CDS BMEA_B1013 NC_012442.1 993415 994245 R hypothetical protein complement(993415..994245) Brucella melitensis ATCC 23457 7671509 YP_002734755.1 CDS dapD NC_012442.1 994462 995316 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 994462..995316 Brucella melitensis ATCC 23457 7671510 YP_002734756.1 CDS BMEA_B1015 NC_012442.1 995460 996014 R transglutaminase family protein cysteine peptidase BTLCP complement(995460..996014) Brucella melitensis ATCC 23457 7671511 YP_002734757.1 CDS dapE NC_012442.1 996299 997486 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 996299..997486 Brucella melitensis ATCC 23457 7671512 YP_002734758.1 CDS BMEA_B1017 NC_012442.1 997549 998154 D hypothetical protein 997549..998154 Brucella melitensis ATCC 23457 7671513 YP_002734759.1 CDS truA NC_012442.1 998329 999084 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(998329..999084) Brucella melitensis ATCC 23457 7671514 YP_002734760.1 CDS fmt NC_012442.1 999088 1000008 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(999088..1000008) Brucella melitensis ATCC 23457 7671515 YP_002734761.1 CDS def NC_012442.1 1000008 1000571 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1000008..1000571) Brucella melitensis ATCC 23457 7671516 YP_002734762.1 CDS BMEA_B1021 NC_012442.1 1000638 1001861 D hypothetical protein 1000638..1001861 Brucella melitensis ATCC 23457 7671517 YP_002734763.1 CDS BMEA_B1022 NC_012442.1 1002082 1002387 R Selenoprotein W-related family protein complement(1002082..1002387) Brucella melitensis ATCC 23457 7671518 YP_002734764.1 CDS BMEA_B1023 NC_012442.1 1002496 1002777 D GIY-YIG catalytic domain-containing protein 1002496..1002777 Brucella melitensis ATCC 23457 7671519 YP_002734765.1 CDS lepA NC_012442.1 1003025 1004833 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1003025..1004833) Brucella melitensis ATCC 23457 7671520 YP_002734766.1 CDS BMEA_B1025 NC_012442.1 1004830 1004961 R hypothetical protein complement(1004830..1004961) Brucella melitensis ATCC 23457 7671521 YP_002734767.1 CDS BMEA_B1026 NC_012442.1 1004997 1005983 D NADH-ubiquinone oxidoreductase 1004997..1005983 Brucella melitensis ATCC 23457 7671522 YP_002734768.1 CDS BMEA_B1027 NC_012442.1 1006084 1006890 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(1006084..1006890) Brucella melitensis ATCC 23457 7671523 YP_002734769.1 CDS BMEA_B1028 NC_012442.1 1006895 1007098 R hypothetical protein complement(1006895..1007098) Brucella melitensis ATCC 23457 7671524 YP_002734770.1 CDS BMEA_B1029 NC_012442.1 1007146 1007838 D hypothetical protein 1007146..1007838 Brucella melitensis ATCC 23457 7671525 YP_002734771.1 CDS BMEA_B1030 NC_012442.1 1007819 1009015 D hypothetical protein 1007819..1009015 Brucella melitensis ATCC 23457 7671526 YP_002734772.1 CDS BMEA_B1031 NC_012442.1 1009017 1009886 D NAD-dependent epimerase/dehydratase 1009017..1009886 Brucella melitensis ATCC 23457 7671527 YP_002734773.1 CDS mepA NC_012442.1 1009887 1010909 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1009887..1010909 Brucella melitensis ATCC 23457 7671528 YP_002734774.1 CDS mgsA NC_012442.1 1011062 1011439 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1011062..1011439 Brucella melitensis ATCC 23457 7671529 YP_002734775.1 CDS glk NC_012442.1 1011520 1012551 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1011520..1012551 Brucella melitensis ATCC 23457 7671530 YP_002734776.1 CDS BMEA_B1035 NC_012442.1 1012778 1014607 D ABC transporter 1012778..1014607 Brucella melitensis ATCC 23457 7671531 YP_002734777.1 CDS dapB NC_012442.1 1014604 1015443 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1014604..1015443 Brucella melitensis ATCC 23457 7671532 YP_002734778.1 CDS BMEA_B1037 NC_012442.1 1015480 1016100 D catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1015480..1016100 Brucella melitensis ATCC 23457 7671533 YP_002734779.1 CDS bluB NC_012442.1 1018780 1019403 D cob(II)yrinic acid a,c-diamide reductase 1018780..1019403 Brucella melitensis ATCC 23457 7671536 YP_002734780.1 CDS BMEA_B1041 NC_012442.1 1019600 1020046 D universal stress protein 1019600..1020046 Brucella melitensis ATCC 23457 7671537 YP_002734781.1 CDS BMEA_B1043 NC_012442.1 1020163 1020381 R hypothetical protein complement(1020163..1020381) Brucella melitensis ATCC 23457 7671538 YP_002734782.1 CDS BMEA_B1044 NC_012442.1 1020535 1020966 D YhhN family protein 1020535..1020966 Brucella melitensis ATCC 23457 7671539 YP_002734783.1 CDS BMEA_B1046 NC_012442.1 1022526 1023383 D endonuclease/exonuclease/phosphatase 1022526..1023383 Brucella melitensis ATCC 23457 7671541 YP_002734784.1 CDS BMEA_B1047 NC_012442.1 1023393 1024853 R cardiolipin synthetase complement(1023393..1024853) Brucella melitensis ATCC 23457 7671542 YP_002734785.1 CDS BMEA_B1048 NC_012442.1 1025025 1025588 D hypothetical protein 1025025..1025588 Brucella melitensis ATCC 23457 7671543 YP_002734786.1 CDS BMEA_B1049 NC_012442.1 1025600 1025713 R hypothetical protein complement(1025600..1025713) Brucella melitensis ATCC 23457 7671544 YP_002734787.1 CDS prfC NC_012442.1 1025749 1027326 D peptide chain release factor 3 1025749..1027326 Brucella melitensis ATCC 23457 7671545 YP_002734788.1 CDS coaBC NC_012442.1 1027323 1028543 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(1027323..1028543) Brucella melitensis ATCC 23457 7671546 YP_002734789.1 CDS ubiB NC_012442.1 1028574 1030157 R 2-polyprenylphenol 6-hydroxylase complement(1028574..1030157) Brucella melitensis ATCC 23457 7671547 YP_002734790.1 CDS ubiE NC_012442.1 1030206 1031015 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1030206..1031015) Brucella melitensis ATCC 23457 7671548 YP_002734791.1 CDS upp NC_012442.1 1031326 1031952 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1031326..1031952 Brucella melitensis ATCC 23457 7671549 YP_002734792.1 CDS BMEA_B1055 NC_012442.1 1032063 1032269 D hypothetical protein 1032063..1032269 Brucella melitensis ATCC 23457 7671550 YP_002734793.1 CDS msrA NC_012442.1 1032282 1032938 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(1032282..1032938) Brucella melitensis ATCC 23457 7671551 YP_002734794.1 CDS BMEA_B1057 NC_012442.1 1032961 1033284 R hypothetical protein complement(1032961..1033284) Brucella melitensis ATCC 23457 7671552 YP_002734795.1 CDS BMEA_B1058 NC_012442.1 1033262 1033414 R hypothetical protein complement(1033262..1033414) Brucella melitensis ATCC 23457 7671553 YP_002734796.1 CDS BMEA_B1060 NC_012442.1 1033955 1034863 R transposase orfB, IS3 family element complement(1033955..1034863) Brucella melitensis ATCC 23457 7671555 YP_002734797.1 CDS BMEA_B1061 NC_012442.1 1034860 1035141 R transposase insN for insertion sequence element IS911 complement(1034860..1035141) Brucella melitensis ATCC 23457 7671556 YP_002734798.1 CDS BMEA_B1063 NC_012442.1 1035559 1036077 D D-lactate dehydrogenase 1035559..1036077 Brucella melitensis ATCC 23457 7671557 YP_002734799.1 CDS BMEA_B1064 NC_012442.1 1036508 1036792 D transcriptional modulator of MazE/toxin, MazF 1036508..1036792 Brucella melitensis ATCC 23457 7671558 YP_002734800.1 CDS BMEA_B1065 NC_012442.1 1036801 1037118 R hypothetical protein complement(1036801..1037118) Brucella melitensis ATCC 23457 7671559 YP_002734801.1 CDS BMEA_B1066 NC_012442.1 1037291 1038547 R hypothetical protein complement(1037291..1038547) Brucella melitensis ATCC 23457 7671560 YP_002734802.1 CDS BMEA_B1067 NC_012442.1 1038642 1039301 R putative L-fuculose-1-phosphate aldolase subunit P complement(1038642..1039301) Brucella melitensis ATCC 23457 7671561 YP_002734803.1 CDS BMEA_B1069 NC_012442.1 1041326 1042531 R glutamate-1-semialdehyde 2,1-aminomutase complement(1041326..1042531) Brucella melitensis ATCC 23457 7671563 YP_002734804.1 CDS BMEA_B1070 NC_012442.1 1042647 1043936 D ABC transporter ATP-binding protein 1042647..1043936 Brucella melitensis ATCC 23457 7671564 YP_002734805.1 CDS BMEA_B1071 NC_012442.1 1043992 1044807 D ABC transporter permease 1043992..1044807 Brucella melitensis ATCC 23457 7671565 YP_002734806.1 CDS BMEA_B1072 NC_012442.1 1044804 1045607 D ABC transporter permease 1044804..1045607 Brucella melitensis ATCC 23457 7671566 YP_002734807.1 CDS BMEA_B1073 NC_012442.1 1045600 1046682 D ABC transporter substrate-binding protein 1045600..1046682 Brucella melitensis ATCC 23457 7671567 YP_002734808.1 CDS BMEA_B1074 NC_012442.1 1046728 1048146 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(1046728..1048146) Brucella melitensis ATCC 23457 7671568 YP_002734809.1 CDS BMEA_B1075 NC_012442.1 1048161 1049033 R hypothetical protein complement(1048161..1049033) Brucella melitensis ATCC 23457 7671569 YP_002734810.1 CDS BMEA_B1076 NC_012442.1 1049033 1050010 R peptide ABC transporter ATPase complement(1049033..1050010) Brucella melitensis ATCC 23457 7671570 YP_002734811.1 CDS BMEA_B1077 NC_012442.1 1050007 1050999 R ABC transporter complement(1050007..1050999) Brucella melitensis ATCC 23457 7671571 YP_002734812.1 CDS BMEA_B1079 NC_012442.1 1051828 1052838 R binding-protein-dependent transport systems inner membrane component complement(1051828..1052838) Brucella melitensis ATCC 23457 7671573 YP_002734813.1 CDS BMEA_B1080 NC_012442.1 1052874 1054430 R glutathione-binding protein GsiB complement(1052874..1054430) Brucella melitensis ATCC 23457 7671574 YP_002734814.1 CDS BMEA_B1081 NC_012442.1 1054496 1054978 R GntR family transcriptional regulator complement(1054496..1054978) Brucella melitensis ATCC 23457 7671575 YP_002734815.1 CDS BMEA_B1082 NC_012442.1 1055202 1056206 R ABC transporter complement(1055202..1056206) Brucella melitensis ATCC 23457 7671576 YP_002734816.1 CDS BMEA_B1083 NC_012442.1 1056203 1057201 R ABC transporter complement(1056203..1057201) Brucella melitensis ATCC 23457 7671577 YP_002734817.1 CDS BMEA_B1084 NC_012442.1 1057204 1058094 R peptide ABC transporter permease complement(1057204..1058094) Brucella melitensis ATCC 23457 7671578 YP_002734818.1 CDS BMEA_B1085 NC_012442.1 1058087 1059031 R peptide ABC transporter permease complement(1058087..1059031) Brucella melitensis ATCC 23457 7671579 YP_002734819.1 CDS BMEA_B1086 NC_012442.1 1059184 1060728 R extracellular solute-binding protein complement(1059184..1060728) Brucella melitensis ATCC 23457 7671580 YP_002734820.1 CDS BMEA_B1088 NC_012442.1 1063361 1064503 R acyl-CoA dehydrogenase complement(1063361..1064503) Brucella melitensis ATCC 23457 7671582 YP_002734821.1 CDS BMEA_B1089 NC_012442.1 1064620 1065468 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1064620..1065468 Brucella melitensis ATCC 23457 7671583 YP_002734822.1 CDS BMEA_B1090 NC_012442.1 1065470 1066990 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxy-acyl-CoA dehydrogenase 1065470..1066990 Brucella melitensis ATCC 23457 7671584 YP_002734823.1 CDS BMEA_B1091 NC_012442.1 1067005 1069182 D 2-oxoisovalerate dehydrogenase subunit beta 1067005..1069182 Brucella melitensis ATCC 23457 7671585 YP_002734824.1 CDS BMEA_B1092 NC_012442.1 1069212 1070831 D glutathione-binding protein GsiB 1069212..1070831 Brucella melitensis ATCC 23457 7671586 YP_002734825.1 CDS BMEA_B1093 NC_012442.1 1070915 1072201 R branched-chain alpha-keto acid dehydrogenase subunit E2 complement(1070915..1072201) Brucella melitensis ATCC 23457 7671587 YP_002734826.1 CDS BMEA_B1094 NC_012442.1 1072261 1073067 R transcriptional regulator complement(1072261..1073067) Brucella melitensis ATCC 23457 7671588 YP_002734827.1 CDS BMEA_B1095 NC_012442.1 1073253 1074266 D dipeptide transport system permease DppB 1073253..1074266 Brucella melitensis ATCC 23457 7671589 YP_002734828.1 CDS BMEA_B1096 NC_012442.1 1074278 1074934 D binding-protein-dependent transport systems inner membrane component 1074278..1074934 Brucella melitensis ATCC 23457 7671590 YP_002734829.1 CDS BMEA_B1097 NC_012442.1 1074947 1075984 D ABC transporter 1074947..1075984 Brucella melitensis ATCC 23457 7671591 YP_002734830.1 CDS BMEA_B1098 NC_012442.1 1075977 1076981 D ABC transporter 1075977..1076981 Brucella melitensis ATCC 23457 7671592 YP_002734831.1 CDS BMEA_B1099 NC_012442.1 1077037 1078299 D L-carnitine dehydratase/bile acid-inducible protein F 1077037..1078299 Brucella melitensis ATCC 23457 7671593 YP_002734832.1 CDS BMEA_B1101 NC_012442.1 1079825 1079953 R hypothetical protein complement(1079825..1079953) Brucella melitensis ATCC 23457 7671595 YP_002734833.1 CDS BMEA_B1102 NC_012442.1 1079950 1080681 R transcriptional regulatory protein complement(1079950..1080681) Brucella melitensis ATCC 23457 7671596 YP_002734834.1 CDS BMEA_B1103 NC_012442.1 1081201 1082082 D Integrase, catalytic domain-containing protein 1081201..1082082 Brucella melitensis ATCC 23457 7671597 YP_002734835.1 CDS BMEA_B1106 NC_012442.1 1082549 1082701 D hypothetical protein 1082549..1082701 Brucella melitensis ATCC 23457 7671600 YP_002734836.1 CDS BMEA_B1108 NC_012442.1 1085656 1085898 D hypothetical protein 1085656..1085898 Brucella melitensis ATCC 23457 7671602 YP_002734837.1 CDS BMEA_B1112 NC_012442.1 1088574 1089440 D BadF/BadG/BcrA/BcrD type ATPase 1088574..1089440 Brucella melitensis ATCC 23457 7671606 YP_002734838.1 CDS BMEA_B1113 NC_012442.1 1089651 1090151 D Rrf2 family transcriptional regulator 1089651..1090151 Brucella melitensis ATCC 23457 7671607 YP_002734839.1 CDS BMEA_B1114 NC_012442.1 1090212 1091414 R cobalamin synthesis protein/P47K family protein complement(1090212..1091414) Brucella melitensis ATCC 23457 7671608 YP_002734840.1 CDS BMEA_B1115 NC_012442.1 1091439 1091579 D hypothetical protein 1091439..1091579 Brucella melitensis ATCC 23457 7671609 YP_002734841.1 CDS BMEA_B1116 NC_012442.1 1091581 1092585 R zinc uptake ABC transporter substrate-binding protein complement(1091581..1092585) Brucella melitensis ATCC 23457 7671610 YP_002734842.1 CDS BMEA_B1117 NC_012442.1 1092812 1093708 D Zinc import ATP-binding protein znuC 1092812..1093708 Brucella melitensis ATCC 23457 7671611 YP_002734843.1 CDS BMEA_B1118 NC_012442.1 1093662 1094522 D zinc ABC transporter permease 1093662..1094522 Brucella melitensis ATCC 23457 7671612 YP_002734844.1 CDS BMEA_B1119 NC_012442.1 1094519 1094956 D ferric uptake regulator Fur family protein 1094519..1094956 Brucella melitensis ATCC 23457 7671613 YP_002734845.1 CDS BMEA_B1120 NC_012442.1 1095083 1095418 D type IV pilus assembly PilZ 1095083..1095418 Brucella melitensis ATCC 23457 7671614 YP_002734846.1 CDS BMEA_B1121 NC_012442.1 1095406 1095933 R hypothetical protein complement(1095406..1095933) Brucella melitensis ATCC 23457 7671615 YP_002734847.1 CDS BMEA_B1122 NC_012442.1 1095930 1096406 R hypothetical protein complement(1095930..1096406) Brucella melitensis ATCC 23457 7671616 YP_002734848.1 CDS BMEA_B1123 NC_012442.1 1096533 1097123 R hypothetical protein complement(1096533..1097123) Brucella melitensis ATCC 23457 7671617 YP_002734849.1 CDS BMEA_B1124 NC_012442.1 1097191 1097598 R hypothetical protein complement(1097191..1097598) Brucella melitensis ATCC 23457 7671618 YP_002734850.1 CDS fliR NC_012442.1 1097606 1098373 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(1097606..1098373) Brucella melitensis ATCC 23457 7671619 YP_002734851.1 CDS fliQ NC_012442.1 1100640 1100906 R FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ complement(1100640..1100906) Brucella melitensis ATCC 23457 7671621 YP_002734852.1 CDS flgD NC_012442.1 1100918 1101331 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein complement(1100918..1101331) Brucella melitensis ATCC 23457 7671622 YP_002734853.1 CDS flbT NC_012442.1 1101328 1101786 R post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT complement(1101328..1101786) Brucella melitensis ATCC 23457 7671623 YP_002734854.1 CDS flaF NC_012442.1 1101788 1102132 R acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF complement(1101788..1102132) Brucella melitensis ATCC 23457 7671624 YP_002734855.1 CDS flgL NC_012442.1 1102264 1103310 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL complement(1102264..1103310) Brucella melitensis ATCC 23457 7671625 YP_002734856.1 CDS flgK NC_012442.1 1103316 1104770 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1103316..1104770) Brucella melitensis ATCC 23457 7671626 YP_002734857.1 CDS flgE NC_012442.1 1104895 1106085 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(1104895..1106085) Brucella melitensis ATCC 23457 7671627 YP_002734858.1 CDS BMEA_B1134 NC_012442.1 1106496 1107179 R protein petR complement(1106496..1107179) Brucella melitensis ATCC 23457 7671628 YP_002734859.1 CDS BMEA_B1135 NC_012442.1 1107507 1108079 R Lytic transglycosylase catalytic complement(1107507..1108079) Brucella melitensis ATCC 23457 7671629 YP_002734860.1 CDS BMEA_B1136 NC_012442.1 1108033 1109307 R flagellar hook-length control protein complement(1108033..1109307) Brucella melitensis ATCC 23457 7671630 YP_002734861.1 CDS BMEA_B1137 NC_012442.1 1109304 1110596 R a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation; chemotaxis protein complement(1109304..1110596) Brucella melitensis ATCC 23457 7671631 YP_002734862.1 CDS motB NC_012442.1 1110593 1111693 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1110593..1111693) Brucella melitensis ATCC 23457 7671632 YP_002734863.1 CDS BMEA_B1139 NC_012442.1 1111690 1112370 R hypothetical protein complement(1111690..1112370) Brucella melitensis ATCC 23457 7671633 YP_002734864.1 CDS BMEA_B1141 NC_012442.1 1114318 1115166 R Flagellin A complement(1114318..1115166) Brucella melitensis ATCC 23457 7671635 YP_002734865.1 CDS BMEA_B1143 NC_012442.1 1126187 1127242 R hypothetical protein complement(1126187..1127242) Brucella melitensis ATCC 23457 7671637 YP_002734866.1 CDS xylF NC_012442.1 1127816 1128835 D D-xylose ABC transporter substrate-binding protein 1127816..1128835 Brucella melitensis ATCC 23457 7671638 YP_002734867.1 CDS xylG NC_012442.1 1128997 1130532 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 1128997..1130532 Brucella melitensis ATCC 23457 7671639 YP_002734868.1 CDS BMEA_B1146 NC_012442.1 1130675 1131844 D monosaccharide-transporting ATPase 1130675..1131844 Brucella melitensis ATCC 23457 7671640 YP_002734869.1 CDS BMEA_B1147 NC_012442.1 1131888 1132091 D hypothetical protein 1131888..1132091 Brucella melitensis ATCC 23457 7671641 YP_002734870.1 CDS BMEA_B1148 NC_012442.1 1132402 1133370 D AraC family transcriptional regulator 1132402..1133370 Brucella melitensis ATCC 23457 7671642 YP_002734871.1 CDS BMEA_B1150 NC_012442.1 1134876 1135013 D hypothetical protein 1134876..1135013 Brucella melitensis ATCC 23457 7671644 YP_002734872.1 CDS hpaI NC_012442.1 1135033 1135842 R 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase complement(1135033..1135842) Brucella melitensis ATCC 23457 7671645 YP_002734873.1 CDS hpaH NC_012442.1 1136060 1136863 R 2-oxo-hepta-3-ene-1,7-dioic acid hydratase complement(1136060..1136863) Brucella melitensis ATCC 23457 7671646 YP_002734874.1 CDS BMEA_B1154 NC_012442.1 1136867 1137733 R Fumarylacetoacetate hydrolase domain-containing protein 2 complement(1136867..1137733) Brucella melitensis ATCC 23457 7671647 YP_002734875.1 CDS hpaD NC_012442.1 1137802 1138782 R 3,4-dihydroxyphenylacetate 2,3-dioxygenase complement(1137802..1138782) Brucella melitensis ATCC 23457 7671648 YP_002734876.1 CDS hpaE NC_012442.1 1138837 1140351 R 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase complement(1138837..1140351) Brucella melitensis ATCC 23457 7671649 YP_002734877.1 CDS BMEA_B1157 NC_012442.1 1140421 1140813 R 5-carboxymethyl-2-hydroxymuconate Delta-isomerase complement(1140421..1140813) Brucella melitensis ATCC 23457 7671650 YP_002734878.1 CDS hpaR NC_012442.1 1140979 1141470 D homoprotocatechuate degradation operon regulator HpaR 1140979..1141470 Brucella melitensis ATCC 23457 7671651 YP_002734879.1 CDS BMEA_B1159 NC_012442.1 1141460 1142452 R Homoserine kinase complement(1141460..1142452) Brucella melitensis ATCC 23457 7671652 YP_002734880.1 CDS BMEA_B1160 NC_012442.1 1142457 1143740 R aminotransferase class-III protein complement(1142457..1143740) Brucella melitensis ATCC 23457 7671653 YP_002734881.1 CDS BMEA_B1161 NC_012442.1 1143742 1145100 R hypothetical protein complement(1143742..1145100) Brucella melitensis ATCC 23457 7671654 YP_002734882.1 CDS BMEA_B1162 NC_012442.1 1145113 1145757 R HAD-superfamily hydrolase complement(1145113..1145757) Brucella melitensis ATCC 23457 7671655 YP_002734883.1 CDS BMEA_B1163 NC_012442.1 1145754 1147010 R hypothetical protein complement(1145754..1147010) Brucella melitensis ATCC 23457 7671656 YP_002734884.1 CDS BMEA_B1164 NC_012442.1 1147010 1147792 R HTH-type transcriptional repressor AllR complement(1147010..1147792) Brucella melitensis ATCC 23457 7671657 YP_002734885.1 CDS BMEA_B1165 NC_012442.1 1148042 1149535 D amino acid permease-associated protein 1148042..1149535 Brucella melitensis ATCC 23457 7671658 YP_002734886.1 CDS BMEA_B1166 NC_012442.1 1149607 1151085 D aldehyde dehydrogenase 1149607..1151085 Brucella melitensis ATCC 23457 7671659 YP_002734887.1 CDS BMEA_B1167 NC_012442.1 1151244 1152926 D exoenzymes regulatory protein AepA 1151244..1152926 Brucella melitensis ATCC 23457 7671660 YP_002734888.1 CDS BMEA_B1168 NC_012442.1 1152993 1154174 D hypothetical protein 1152993..1154174 Brucella melitensis ATCC 23457 7671661 YP_002734889.1 CDS BMEA_B1169 NC_012442.1 1154247 1155116 D hypothetical protein 1154247..1155116 Brucella melitensis ATCC 23457 7671662 YP_002734890.1 CDS BMEA_B1171 NC_012442.1 1156812 1157516 D branched-chain amino acid transport ATP-binding protein livF 1156812..1157516 Brucella melitensis ATCC 23457 7671664 YP_002734891.1 CDS BMEA_B1172 NC_012442.1 1157611 1157934 R hypothetical protein complement(1157611..1157934) Brucella melitensis ATCC 23457 7671665 YP_002734892.1 CDS BMEA_B1174 NC_012442.1 1158824 1159558 R GntR family transcriptional regulator complement(1158824..1159558) Brucella melitensis ATCC 23457 7671667 YP_002734893.1 CDS BMEA_B1175 NC_012442.1 1159703 1160968 R sn-glycerol-3-phosphate-binding periplasmic protein UgpB complement(1159703..1160968) Brucella melitensis ATCC 23457 7671668 YP_002734894.1 CDS BMEA_B1176 NC_012442.1 1161003 1161824 R hypothetical protein complement(1161003..1161824) Brucella melitensis ATCC 23457 7671669 YP_002734895.1 CDS BMEA_B1177 NC_012442.1 1161835 1162794 R hypothetical protein complement(1161835..1162794) Brucella melitensis ATCC 23457 7671670 YP_002734896.1 CDS BMEA_B1178 NC_012442.1 1162760 1163932 R sn-glycerol-3-phosphate import ATP-binding protein UgpC complement(1162760..1163932) Brucella melitensis ATCC 23457 7671671 YP_002734897.1 CDS BMEA_B1179 NC_012442.1 1163929 1164774 R metallophosphoesterase complement(1163929..1164774) Brucella melitensis ATCC 23457 7671672 YP_002734898.1 CDS BMEA_B1180 NC_012442.1 1165049 1166536 R arylsulfatase D complement(1165049..1166536) Brucella melitensis ATCC 23457 7671673 YP_002734899.1 CDS BMEA_B1181 NC_012442.1 1166679 1167638 R aliphatic sulfonate ABC transporter substrate-binding protein complement(1166679..1167638) Brucella melitensis ATCC 23457 7671674 YP_002734900.1 CDS BMEA_B1182 NC_012442.1 1167654 1168367 R ABC transporter complement(1167654..1168367) Brucella melitensis ATCC 23457 7671675 YP_002734901.1 CDS BMEA_B1183 NC_012442.1 1168376 1169116 R binding-protein-dependent transport systems inner membrane component complement(1168376..1169116) Brucella melitensis ATCC 23457 7671676 YP_002734902.1 CDS BMEA_B1184 NC_012442.1 1169113 1170237 R ROK family protein complement(1169113..1170237) Brucella melitensis ATCC 23457 7671677 YP_002734903.1 CDS BMEA_B1185 NC_012442.1 1170493 1172478 R Heme transporter bhuA complement(1170493..1172478) Brucella melitensis ATCC 23457 7671678 YP_002734904.1 CDS BMEA_B1186 NC_012442.1 1172921 1173724 D hypothetical protein 1172921..1173724 Brucella melitensis ATCC 23457 7671679 YP_002734905.1 CDS BMEA_B1187 NC_012442.1 1173703 1173882 D hypothetical protein 1173703..1173882 Brucella melitensis ATCC 23457 7671680 YP_002734906.1 CDS BMEA_B1188 NC_012442.1 1173889 1175094 D extracellular ligand-binding receptor 1173889..1175094 Brucella melitensis ATCC 23457 7671681 YP_002734907.1 CDS BMEA_B1189 NC_012442.1 1175296 1176159 D high-affinity branched-chain amino acid transporter membrane protein 1175296..1176159 Brucella melitensis ATCC 23457 7671682 YP_002734908.1 CDS BMEA_B1190 NC_012442.1 1176156 1177103 D high-affinity branched-chain amino acid transporter membrane protein 1176156..1177103 Brucella melitensis ATCC 23457 7671683 YP_002734909.1 CDS BMEA_B1192 NC_012442.1 1177829 1178557 D high-affinity branched-chain amino acid transporter ATP-binding protein 1177829..1178557 Brucella melitensis ATCC 23457 7671685 YP_002734910.1 CDS BMEA_B1193 NC_012442.1 1178586 1180526 R heavy metal translocating P-type ATPase complement(1178586..1180526) Brucella melitensis ATCC 23457 7671686 YP_002734911.1 CDS hemN NC_012442.1 1180806 1182158 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1180806..1182158) Brucella melitensis ATCC 23457 7671687 YP_002734912.1 CDS BMEA_B1195 NC_012442.1 1182251 1182475 R hypothetical protein complement(1182251..1182475) Brucella melitensis ATCC 23457 7671688 YP_002734913.1 CDS BMEA_B1196 NC_012442.1 1182442 1182846 R hypothetical protein complement(1182442..1182846) Brucella melitensis ATCC 23457 7671689 YP_002734914.1 CDS repA NC_012442.1 1183060 1184253 D plasmid partitioning protein RepA 1183060..1184253 Brucella melitensis ATCC 23457 7671690 YP_002734915.1 CDS repB NC_012442.1 1184318 1185304 D plasmid partitioning protein RepB 1184318..1185304 Brucella melitensis ATCC 23457 7671691 BMEA_A0024 tRNA BMEA_A0024 NC_012441.1 28309 28381 R tRNA-Ala complement(28309..28381) Brucella melitensis ATCC 23457 7678249 BMEA_A0204 tRNA BMEA_A0204 NC_012441.1 207621 207694 D tRNA-Pro 207621..207694 Brucella melitensis ATCC 23457 7677425 BMEA_A0281 tRNA BMEA_A0281 NC_012441.1 279899 279971 R tRNA-Phe complement(279899..279971) Brucella melitensis ATCC 23457 7677989 BMEA_A0291 tRNA BMEA_A0291 NC_012441.1 286258 286329 D tRNA-Thr 286258..286329 Brucella melitensis ATCC 23457 7677999 BMEA_A0307 tRNA BMEA_A0307 NC_012441.1 300470 300543 R tRNA-Arg complement(300470..300543) Brucella melitensis ATCC 23457 7678015 BMEA_A0548 tRNA BMEA_A0548 NC_012441.1 533206 533277 D tRNA-Gln 533206..533277 Brucella melitensis ATCC 23457 7676847 BMEA_A0676 tRNA BMEA_A0676 NC_012441.1 652061 652148 R tRNA-Ser complement(652061..652148) Brucella melitensis ATCC 23457 7676331 BMEA_A0758 tRNA BMEA_A0758 NC_012441.1 724968 725041 D tRNA-Pro 724968..725041 Brucella melitensis ATCC 23457 7676895 BMEA_A0760 tRNA BMEA_A0760 NC_012441.1 725606 725679 D tRNA-Arg 725606..725679 Brucella melitensis ATCC 23457 7676897 BMEA_A0819 tRNA BMEA_A0819 NC_012441.1 784967 785040 R tRNA-Pro complement(784967..785040) Brucella melitensis ATCC 23457 7677908 BMEA_A0840 tRNA BMEA_A0840 NC_012441.1 799457 799529 R tRNA-Val complement(799457..799529) Brucella melitensis ATCC 23457 7677929 BMEA_A0842 tRNA BMEA_A0842 NC_012441.1 799940 800013 D tRNA-Asp 799940..800013 Brucella melitensis ATCC 23457 7677931 BMEA_A0937 tRNA BMEA_A0937 NC_012441.1 892863 892942 D tRNA-Leu 892863..892942 Brucella melitensis ATCC 23457 7677702 BMEA_A0975 tRNA BMEA_A0975 NC_012441.1 931936 932008 R tRNA-Thr complement(931936..932008) Brucella melitensis ATCC 23457 7677269 BMEA_A0998 tRNA BMEA_A0998 NC_012441.1 955191 955262 R tRNA-Val complement(955191..955262) Brucella melitensis ATCC 23457 7677292 BMEA_A0999 tRNA BMEA_A0999 NC_012441.1 955679 955752 D tRNA-Arg 955679..955752 Brucella melitensis ATCC 23457 7677293 BMEA_A1002 tRNA BMEA_A1002 NC_012441.1 956460 956530 R tRNA-Gly complement(956460..956530) Brucella melitensis ATCC 23457 7677296 BMEA_A1091 tRNA BMEA_A1091 NC_012441.1 1038161 1038243 D tRNA-Leu 1038161..1038243 Brucella melitensis ATCC 23457 7677851 BMEA_A1120 tRNA BMEA_A1120 NC_012441.1 1066911 1066992 D tRNA-Leu 1066911..1066992 Brucella melitensis ATCC 23457 7677879 BMEA_A1128 tRNA BMEA_A1128 NC_012441.1 1075156 1075237 D tRNA-Leu 1075156..1075237 Brucella melitensis ATCC 23457 7676205 BMEA_A1295 tRNA BMEA_A1295 NC_012441.1 1238407 1238479 R tRNA-Trp complement(1238407..1238479) Brucella melitensis ATCC 23457 7677023 BMEA_A1298 tRNA BMEA_A1298 NC_012441.1 1239905 1239975 R tRNA-Gly complement(1239905..1239975) Brucella melitensis ATCC 23457 7677026 BMEA_A1299 tRNA BMEA_A1299 NC_012441.1 1240003 1240084 R tRNA-Tyr complement(1240003..1240084) Brucella melitensis ATCC 23457 7677027 BMEA_A1325 tRNA BMEA_A1325 NC_012441.1 1261240 1261311 D tRNA-Glu 1261240..1261311 Brucella melitensis ATCC 23457 7677052 BMEA_A1326 tRNA BMEA_A1326 NC_012441.1 1261462 1261533 D tRNA-Glu 1261462..1261533 Brucella melitensis ATCC 23457 7677053 BMEA_A1383 tRNA BMEA_A1383 NC_012441.1 1317606 1317678 D tRNA-Lys 1317606..1317678 Brucella melitensis ATCC 23457 7676449 BMEA_A1526 tRNA BMEA_A1526 NC_012441.1 1449562 1449635 R tRNA-Ile complement(1449562..1449635) Brucella melitensis ATCC 23457 7678219 BMEA_A1655 tRNA BMEA_A1655 NC_012441.1 1568023 1568096 D tRNA-Met 1568023..1568096 Brucella melitensis ATCC 23457 7676401 BMEA_A1658 tRNA BMEA_A1658 NC_012441.1 1569782 1569855 R tRNA-His complement(1569782..1569855) Brucella melitensis ATCC 23457 7676404 BMEA_A1669 tRNA BMEA_A1669 NC_012441.1 1584033 1584103 D tRNA-Gln 1584033..1584103 Brucella melitensis ATCC 23457 7676415 BMEA_A1688 tRNA BMEA_A1688 NC_012441.1 1604204 1604277 R tRNA-Met complement(1604204..1604277) Brucella melitensis ATCC 23457 7676597 BMEA_A1693 tRNA BMEA_A1693 NC_012441.1 1607946 1608018 R tRNA-Ala complement(1607946..1608018) Brucella melitensis ATCC 23457 7676602 BMEA_A1694 tRNA BMEA_A1694 NC_012441.1 1608035 1608108 R tRNA-Ile complement(1608035..1608108) Brucella melitensis ATCC 23457 7676603 BMEA_A1710 tRNA BMEA_A1710 NC_012441.1 1623057 1623128 D tRNA-Glu 1623057..1623128 Brucella melitensis ATCC 23457 7676619 BMEA_A1900 tRNA BMEA_A1900 NC_012441.1 1799561 1799647 D tRNA-Ser 1799561..1799647 Brucella melitensis ATCC 23457 7677385 BMEA_A1909 tRNA BMEA_A1909 NC_012441.1 1807603 1807676 R tRNA-Met complement(1807603..1807676) Brucella melitensis ATCC 23457 7676935 BMEA_A1913 tRNA BMEA_A1913 NC_012441.1 1811345 1811417 R tRNA-Ala complement(1811345..1811417) Brucella melitensis ATCC 23457 7677562 BMEA_A1914 tRNA BMEA_A1914 NC_012441.1 1811434 1811507 R tRNA-Ile complement(1811434..1811507) Brucella melitensis ATCC 23457 7677563 BMEA_A2007 tRNA BMEA_A2007 NC_012441.1 1899812 1899893 D tRNA-Leu 1899812..1899893 Brucella melitensis ATCC 23457 7677735 BMEA_A2049 tRNA BMEA_A2049 NC_012441.1 1937267 1937339 R tRNA-Ala complement(1937267..1937339) Brucella melitensis ATCC 23457 7677776 BMEA_A2099 tRNA BMEA_A2099 NC_012441.1 1981548 1981621 D tRNA-Arg 1981548..1981621 Brucella melitensis ATCC 23457 7678066 BMEA_B0045 tRNA BMEA_B0045 NC_012442.1 39454 39525 R tRNA-Val complement(39454..39525) Brucella melitensis ATCC 23457 7670568 BMEA_B0324 tRNA BMEA_B0324 NC_012442.1 304452 304525 R tRNA-Asp complement(304452..304525) Brucella melitensis ATCC 23457 7670838 BMEA_B0533 tRNA BMEA_B0533 NC_012442.1 520026 520112 R tRNA-Ser complement(520026..520112) Brucella melitensis ATCC 23457 7671042 BMEA_B0561 tRNA BMEA_B0561 NC_012442.1 552490 552562 R tRNA-Lys complement(552490..552562) Brucella melitensis ATCC 23457 7671070 BMEA_B0593 tRNA BMEA_B0593 NC_012442.1 584443 584513 D tRNA-Cys 584443..584513 Brucella melitensis ATCC 23457 7671102 BMEA_B0600 tRNA BMEA_B0600 NC_012442.1 588808 588879 R tRNA-Asn complement(588808..588879) Brucella melitensis ATCC 23457 7671109 BMEA_B0811 tRNA BMEA_B0811 NC_012442.1 797437 797509 D tRNA-Thr 797437..797509 Brucella melitensis ATCC 23457 7671310 BMEA_B0876 tRNA BMEA_B0876 NC_012442.1 857731 857802 D tRNA-Gly 857731..857802 Brucella melitensis ATCC 23457 7671374 BMEA_B1003 tRNA BMEA_B1003 NC_012442.1 986217 986288 D tRNA-Gly 986217..986288 Brucella melitensis ATCC 23457 7671499 BMEA_B1038 tRNA BMEA_B1038 NC_012442.1 1016249 1016332 D tRNA-Leu 1016249..1016332 Brucella melitensis ATCC 23457 7671534 BMEA_B1059 tRNA BMEA_B1059 NC_012442.1 1033657 1033743 D tRNA-Ser 1033657..1033743 Brucella melitensis ATCC 23457 7671554 BMEA_B1104 tRNA BMEA_B1104 NC_012442.1 1082190 1082263 R tRNA-Met complement(1082190..1082263) Brucella melitensis ATCC 23457 7671598 BMEA_B1109 tRNA BMEA_B1109 NC_012442.1 1085932 1086004 R tRNA-Ala complement(1085932..1086004) Brucella melitensis ATCC 23457 7671603 BMEA_B1110 tRNA BMEA_B1110 NC_012442.1 1086021 1086094 R tRNA-Ile complement(1086021..1086094) Brucella melitensis ATCC 23457 7671604 BMEA_A1689 rRNA BMEA_A1689 NC_012441.1 1604382 1604500 R 5S ribosomal RNA complement(1604382..1604500) Brucella melitensis ATCC 23457 7676598 BMEA_A1691 rRNA BMEA_A1691 NC_012441.1 1604716 1607619 R 23S ribosomal RNA complement(join(1604716..1607332,1607448..1607619)) Brucella melitensis ATCC 23457 7676600 BMEA_A1695 rRNA BMEA_A1695 NC_012441.1 1608389 1609873 R 16S ribosomal RNA complement(1608389..1609873) Brucella melitensis ATCC 23457 7676604 BMEA_A1910 rRNA BMEA_A1910 NC_012441.1 1807781 1807899 R 5S ribosomal RNA complement(1807781..1807899) Brucella melitensis ATCC 23457 7677559 BMEA_A1912 rRNA BMEA_A1912 NC_012441.1 1808115 1811018 R 23S ribosomal RNA complement(join(1808115..1810731,1810847..1811018)) Brucella melitensis ATCC 23457 7677561 BMEA_A1915 rRNA BMEA_A1915 NC_012441.1 1811788 1813272 R 16S ribosomal RNA complement(1811788..1813272) Brucella melitensis ATCC 23457 7677564 BMEA_B1105 rRNA BMEA_B1105 NC_012442.1 1082368 1082486 R 5S ribosomal RNA complement(1082368..1082486) Brucella melitensis ATCC 23457 7671599 BMEA_B1107 rRNA BMEA_B1107 NC_012442.1 1082702 1085605 R 23S ribosomal RNA complement(join(1082702..1085318,1085434..1085605)) Brucella melitensis ATCC 23457 7671601 BMEA_B1111 rRNA BMEA_B1111 NC_012442.1 1086375 1087859 R 16S ribosomal RNA complement(1086375..1087859) Brucella melitensis ATCC 23457 7671605